LOCUS       DACCVZ010000001        88533 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.001, whole genome shotgun sequence.
ACCESSION   DACCVZ010000001 DACCVZ010000000
VERSION     DACCVZ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 88533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.001"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            1..519
                     /locus_tag="IVW63_000001"
     CDS             1..519
                     /locus_tag="IVW63_000001"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP7858310.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            647..1330
                     /locus_tag="IVW63_000002"
     CDS             647..1330
                     /locus_tag="IVW63_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAP7858311.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1639..1712
                     /locus_tag="IVW63_000003"
     tRNA            1639..1712
                     /locus_tag="IVW63_000003"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1673..1675,aa:Arg,seq:tct)
     gene            1871..2229
                     /locus_tag="IVW63_000004"
                     /pseudo
     CDS             1871..2229
                     /locus_tag="IVW63_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
     gene            2352..3983
                     /locus_tag="IVW63_000005"
     CDS             2352..3983
                     /locus_tag="IVW63_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HAP7858312.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4045..4686)
                     /locus_tag="IVW63_000006"
     CDS             complement(4045..4686)
                     /locus_tag="IVW63_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAP7858313.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            4968..5276
                     /gene="rplU"
                     /locus_tag="IVW63_000007"
     CDS             4968..5276
                     /gene="rplU"
                     /locus_tag="IVW63_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAP7858314.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5303..5647
                     /locus_tag="IVW63_000008"
     CDS             5303..5647
                     /locus_tag="IVW63_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAP7858315.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5660..5953
                     /gene="rpmA"
                     /locus_tag="IVW63_000009"
     CDS             5660..5953
                     /gene="rpmA"
                     /locus_tag="IVW63_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAP7858316.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6360..9194
                     /locus_tag="IVW63_000010"
     CDS             6360..9194
                     /locus_tag="IVW63_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7858317.1"
                     /translation="MAKRIDRIYMYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNS
                     SKDLNQLVREGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDT
                     KDIFAKIIGANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAH
                     HVIDEETELIVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLD
                     EIHRLPPEGQEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRI
                     PINIKLPAFEKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQL
                     KSNIQLVCARGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKIT
                     VAPNDTIMKIQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFY
                     KDHGFSFNADSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKK
                     INLGEERHTNDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLR
                     ANQASGRIGVVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNV
                     QEVDEGSGVILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDL
                     DMLHESLKNFRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNK
                     RQETELEVLALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVI
                     LDQLLMESELEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTT
                     GIGDEEYGFKINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLED
                     QIKVKVPIEEMYYLLRLVHNQLDKKEYTVP"
     gene            9385..9876
                     /locus_tag="IVW63_000011"
     CDS             9385..9876
                     /locus_tag="IVW63_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIB"
                     /protein_id="HAP7858318.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            9979..10968
                     /gene="manX"
                     /locus_tag="IVW63_000012"
     CDS             9979..10968
                     /gene="manX"
                     /locus_tag="IVW63_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAP7858319.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11001..11804
                     /locus_tag="IVW63_000013"
     CDS             11001..11804
                     /locus_tag="IVW63_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAP7858320.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11825..12739
                     /locus_tag="IVW63_000014"
     CDS             11825..12739
                     /locus_tag="IVW63_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAP7858321.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12822..13196
                     /locus_tag="IVW63_000015"
     CDS             12822..13196
                     /locus_tag="IVW63_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HAP7858322.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13335..13580
                     /locus_tag="IVW63_000016"
     CDS             13335..13580
                     /locus_tag="IVW63_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP7858323.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13752..14816
                     /locus_tag="IVW63_000017"
     CDS             13752..14816
                     /locus_tag="IVW63_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAP7858324.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15062..15487
                     /locus_tag="IVW63_000018"
     CDS             15062..15487
                     /locus_tag="IVW63_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP7858325.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15480..15929
                     /gene="nusB"
                     /locus_tag="IVW63_000019"
     CDS             15480..15929
                     /gene="nusB"
                     /locus_tag="IVW63_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAP7858326.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16026..16880
                     /locus_tag="IVW63_000020"
     CDS             16026..16880
                     /locus_tag="IVW63_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HAP7858327.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            16881..18218
                     /locus_tag="IVW63_000021"
     CDS             16881..18218
                     /locus_tag="IVW63_000021"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAP7858328.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18223..18447
                     /locus_tag="IVW63_000022"
     CDS             18223..18447
                     /locus_tag="IVW63_000022"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAP7858329.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18449..19339
                     /locus_tag="IVW63_000023"
     CDS             18449..19339
                     /locus_tag="IVW63_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAP7858330.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19348..20166
                     /locus_tag="IVW63_000024"
     CDS             19348..20166
                     /locus_tag="IVW63_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HAP7858331.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20273..20722
                     /locus_tag="IVW63_000025"
     CDS             20273..20722
                     /locus_tag="IVW63_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAP7858332.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20740..22422
                     /gene="recN"
                     /locus_tag="IVW63_000026"
     CDS             20740..22422
                     /gene="recN"
                     /locus_tag="IVW63_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAP7858333.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22477..22593)
                     /locus_tag="IVW63_000027"
     CDS             complement(22477..22593)
                     /locus_tag="IVW63_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HAP7858334.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22666..23622)
                     /locus_tag="IVW63_000028"
     CDS             complement(22666..23622)
                     /locus_tag="IVW63_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP7858335.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFTKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23793..24161
                     /locus_tag="IVW63_000029"
     CDS             23793..24161
                     /locus_tag="IVW63_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HAP7858336.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24331..24762
                     /gene="mraZ"
                     /locus_tag="IVW63_000030"
     CDS             24331..24762
                     /gene="mraZ"
                     /locus_tag="IVW63_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAP7858337.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24783..25742
                     /gene="rsmH"
                     /locus_tag="IVW63_000031"
     CDS             24783..25742
                     /gene="rsmH"
                     /locus_tag="IVW63_000031"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAP7858338.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25747..26148
                     /gene="ftsL"
                     /locus_tag="IVW63_000032"
     CDS             25747..26148
                     /gene="ftsL"
                     /locus_tag="IVW63_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAP7858339.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26149..28341
                     /locus_tag="IVW63_000033"
     CDS             26149..28341
                     /locus_tag="IVW63_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAP7858340.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28367..29329
                     /locus_tag="IVW63_000034"
     CDS             28367..29329
                     /locus_tag="IVW63_000034"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAP7858341.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29343..30704
                     /locus_tag="IVW63_000035"
     CDS             29343..30704
                     /locus_tag="IVW63_000035"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAP7858342.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30730..31818
                     /gene="murG"
                     /locus_tag="IVW63_000036"
     CDS             30730..31818
                     /gene="murG"
                     /locus_tag="IVW63_000036"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAP7858343.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            31833..33053
                     /locus_tag="IVW63_000037"
     CDS             31833..33053
                     /locus_tag="IVW63_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAP7858344.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33209..34534
                     /gene="ftsA"
                     /locus_tag="IVW63_000038"
     CDS             33209..34534
                     /gene="ftsA"
                     /locus_tag="IVW63_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAP7858345.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34557..35798
                     /gene="ftsZ"
                     /locus_tag="IVW63_000039"
     CDS             34557..35798
                     /gene="ftsZ"
                     /locus_tag="IVW63_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAP7858346.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35815..36492
                     /locus_tag="IVW63_000040"
     CDS             35815..36492
                     /locus_tag="IVW63_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAP7858347.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36506..37105
                     /locus_tag="IVW63_000041"
     CDS             36506..37105
                     /locus_tag="IVW63_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAP7858348.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37120..37407
                     /locus_tag="IVW63_000042"
     CDS             37120..37407
                     /locus_tag="IVW63_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAP7858349.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37456..38238
                     /locus_tag="IVW63_000043"
     CDS             37456..38238
                     /locus_tag="IVW63_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAP7858350.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38259..38966
                     /locus_tag="IVW63_000044"
     CDS             38259..38966
                     /locus_tag="IVW63_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAP7858351.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39228..42026
                     /gene="ileS"
                     /locus_tag="IVW63_000045"
     CDS             39228..42026
                     /gene="ileS"
                     /locus_tag="IVW63_000045"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAP7858352.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42075..43601)
                     /locus_tag="IVW63_000046"
     CDS             complement(42075..43601)
                     /locus_tag="IVW63_000046"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAP7858353.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43616..44263)
                     /locus_tag="IVW63_000047"
     CDS             complement(43616..44263)
                     /locus_tag="IVW63_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HAP7858354.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44447..44776)
                     /locus_tag="IVW63_000048"
     CDS             complement(44447..44776)
                     /locus_tag="IVW63_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HAP7858355.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            44953..45681
                     /gene="sfsA"
                     /locus_tag="IVW63_000049"
     CDS             44953..45681
                     /gene="sfsA"
                     /locus_tag="IVW63_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAP7858356.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45697..46710
                     /locus_tag="IVW63_000050"
     CDS             45697..46710
                     /locus_tag="IVW63_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP7858357.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46710..47987
                     /locus_tag="IVW63_000051"
     CDS             46710..47987
                     /locus_tag="IVW63_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP7858358.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48050..50752
                     /locus_tag="IVW63_000052"
     CDS             48050..50752
                     /locus_tag="IVW63_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7858359.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            50904..51221
                     /locus_tag="IVW63_000053"
     CDS             50904..51221
                     /locus_tag="IVW63_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7858360.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51251..51571
                     /locus_tag="IVW63_000054"
     CDS             51251..51571
                     /locus_tag="IVW63_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP7858361.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51679..53139
                     /locus_tag="IVW63_000055"
     CDS             51679..53139
                     /locus_tag="IVW63_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7858362.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53207..53428
                     /locus_tag="IVW63_000056"
     CDS             53207..53428
                     /locus_tag="IVW63_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858363.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53459..53641
                     /locus_tag="IVW63_000057"
     CDS             53459..53641
                     /locus_tag="IVW63_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HAP7858364.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53641..54054
                     /locus_tag="IVW63_000058"
     CDS             53641..54054
                     /locus_tag="IVW63_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAP7858365.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54177..55358
                     /locus_tag="IVW63_000059"
     CDS             54177..55358
                     /locus_tag="IVW63_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7858366.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            55747..55820
                     /locus_tag="IVW63_000060"
     tRNA            55747..55820
                     /locus_tag="IVW63_000060"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55781..55783,aa:Arg,seq:cct)
     gene            complement(55889..57028)
                     /locus_tag="IVW63_000061"
     CDS             complement(55889..57028)
                     /locus_tag="IVW63_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7858367.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(57142..57726)
                     /locus_tag="IVW63_000062"
     CDS             complement(57142..57726)
                     /locus_tag="IVW63_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HAP7858368.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            complement(57853..58284)
                     /locus_tag="IVW63_000063"
     CDS             complement(57853..58284)
                     /locus_tag="IVW63_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP7858369.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFTASHFEYSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(58302..58622)
                     /locus_tag="IVW63_000064"
     CDS             complement(58302..58622)
                     /locus_tag="IVW63_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7858370.1"
                     /translation="MITFERIKELAKKQGKSLNKVEEDLGYGKNVLYRLKNSNPSTER
                     LQEIADYFDVSVDYLLGREEKETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            complement(59053..59232)
                     /locus_tag="IVW63_000065"
     CDS             complement(59053..59232)
                     /locus_tag="IVW63_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858371.1"
                     /translation="MNKKTDEIAADLVVAWLNHESQVSTKGESISPKEIAQAYLDIHY
                     AVIYGQLPEDRKNDD"
     gene            59313..60059
                     /locus_tag="IVW63_000066"
     CDS             59313..60059
                     /locus_tag="IVW63_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAP7858372.1"
                     /translation="MNTPQIFSFEQHEVRTFLENDIPYFVANDVAKTLGYKNPSKATN
                     DHCKKSIETWGNDSLGRRQKFKVIPESDVYRLIIKSNLPSAEKFEAWVMEEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            60074..60277
                     /locus_tag="IVW63_000067"
     CDS             60074..60277
                     /locus_tag="IVW63_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7858373.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            60293..60631
                     /locus_tag="IVW63_000068"
     CDS             60293..60631
                     /locus_tag="IVW63_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HAP7858374.1"
                     /translation="MQYLEAKIPVPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            60618..60797
                     /locus_tag="IVW63_000069"
     CDS             60618..60797
                     /locus_tag="IVW63_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858375.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(60840..61310)
                     /locus_tag="IVW63_000070"
     CDS             complement(60840..61310)
                     /locus_tag="IVW63_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858376.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            61397..62095
                     /locus_tag="IVW63_000071"
     CDS             61397..62095
                     /locus_tag="IVW63_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAP7858377.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            62273..62614
                     /locus_tag="IVW63_000072"
     CDS             62273..62614
                     /locus_tag="IVW63_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858378.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            62607..63278
                     /locus_tag="IVW63_000073"
     CDS             62607..63278
                     /locus_tag="IVW63_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAP7858379.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            63284..63970
                     /locus_tag="IVW63_000074"
     CDS             63284..63970
                     /locus_tag="IVW63_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858380.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            63973..64803
                     /locus_tag="IVW63_000075"
     CDS             63973..64803
                     /locus_tag="IVW63_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAP7858381.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            64820..65671
                     /locus_tag="IVW63_000076"
     CDS             64820..65671
                     /locus_tag="IVW63_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP7858382.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALEKAKSYTNEVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNTELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            65668..66027
                     /locus_tag="IVW63_000077"
     CDS             65668..66027
                     /locus_tag="IVW63_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HAP7858383.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANDWKVKLQER
                     FELMPKFELEGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            66042..66203
                     /locus_tag="IVW63_000078"
     CDS             66042..66203
                     /locus_tag="IVW63_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAP7858384.1"
                     /translation="MTTEEVIQMRIRSIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            66200..66505
                     /locus_tag="IVW63_000079"
     CDS             66200..66505
                     /locus_tag="IVW63_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858385.1"
                     /translation="MSVDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKTR
                     RRMPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            66505..66822
                     /locus_tag="IVW63_000080"
     CDS             66505..66822
                     /locus_tag="IVW63_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAP7858386.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILDEYME
                     GSK"
     gene            66819..67205
                     /locus_tag="IVW63_000081"
     CDS             66819..67205
                     /locus_tag="IVW63_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858387.1"
                     /translation="MIPRFRSWYTPFKGKTIGQEMKYGQAGRLITHAEMAPDKYVLMQ
                     STGLKDKNGVEIFEGDVVLVNVSNGFDHLVNEKTVVQESEFHSGLVCKSLISGMEYRI
                     FSHQKMGYEYEVTGNIHENSELLEVE"
     gene            67202..67537
                     /locus_tag="IVW63_000082"
     CDS             67202..67537
                     /locus_tag="IVW63_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858388.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDIHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEQ"
     gene            67683..68252
                     /locus_tag="IVW63_000083"
     CDS             67683..68252
                     /locus_tag="IVW63_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAP7858389.1"
                     /translation="MNKQEAIKKLESIKVIGNDALAACYNESINAGITLMKKIDEPKK
                     LVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLYSVIIAGEYLVKEISCSNEVKLVSTAYLPQYLAH
                     HYQLTEKQIKAIDERYWPFAVPVEEVAEG"
     gene            68419..68724
                     /locus_tag="IVW63_000084"
     CDS             68419..68724
                     /locus_tag="IVW63_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858390.1"
                     /translation="MNVQVYLKRDLARFPRSWDTNSHPSEAEEEGYLMSANMIEITRD
                     DADEFDKKRSWYSVPNPMYTAVIEDYHISDRFILIDLERPKKRIKQYRRCGFSTKKW"
     gene            68748..68945
                     /locus_tag="IVW63_000085"
     CDS             68748..68945
                     /locus_tag="IVW63_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HAP7858391.1"
                     /translation="MNNRHRRVAKLRNQELNVAKVKFEREYGVSAEETYKVASQCVAD
                     ASDAIRKFGISILDIKWEDTE"
     gene            68942..69148
                     /locus_tag="IVW63_000086"
     CDS             68942..69148
                     /locus_tag="IVW63_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858392.1"
                     /translation="MKIYVVKFGNQFYRSDERSIGANTLSIVDILQSARWFDNLEEAN
                     QVSRRLGGLTQVYELVTVDHEGVE"
     gene            69148..69444
                     /locus_tag="IVW63_000087"
     CDS             69148..69444
                     /locus_tag="IVW63_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858393.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTREKPKFKVGDMVRCEA
                     EGFIYPFRGYVEKVLSNSAIIRIENTMECDKWLAKSKENLAVARLVDMEVIESK"
     gene            69520..69933
                     /locus_tag="IVW63_000088"
     CDS             69520..69933
                     /locus_tag="IVW63_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAP7858394.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            70810..71154
                     /locus_tag="IVW63_000089"
     CDS             70810..71154
                     /locus_tag="IVW63_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAP7858395.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            71159..71440
                     /locus_tag="IVW63_000090"
     CDS             71159..71440
                     /locus_tag="IVW63_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858396.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVDIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNIFGYSIEEINYYIDFAEAFIPMVR"
     gene            71543..71857
                     /locus_tag="IVW63_000091"
     CDS             71543..71857
                     /locus_tag="IVW63_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HAP7858397.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            71835..73529
                     /locus_tag="IVW63_000092"
     CDS             71835..73529
                     /locus_tag="IVW63_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAP7858398.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYNIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            73549..74727
                     /locus_tag="IVW63_000093"
     CDS             73549..74727
                     /locus_tag="IVW63_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP7858399.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            74690..75376
                     /locus_tag="IVW63_000094"
     CDS             74690..75376
                     /locus_tag="IVW63_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HAP7858400.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            75376..76536
                     /locus_tag="IVW63_000095"
     CDS             75376..76536
                     /locus_tag="IVW63_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAP7858401.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKEAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YRFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            76546..77421
                     /locus_tag="IVW63_000096"
     CDS             76546..77421
                     /locus_tag="IVW63_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858402.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNTGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            77418..77729
                     /locus_tag="IVW63_000097"
     CDS             77418..77729
                     /locus_tag="IVW63_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858403.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            77719..78072
                     /locus_tag="IVW63_000098"
     CDS             77719..78072
                     /locus_tag="IVW63_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAP7858404.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            78062..78463
                     /locus_tag="IVW63_000099"
     CDS             78062..78463
                     /locus_tag="IVW63_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858405.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            78456..78860
                     /locus_tag="IVW63_000100"
     CDS             78456..78860
                     /locus_tag="IVW63_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858406.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            78872..79477
                     /locus_tag="IVW63_000101"
     CDS             78872..79477
                     /locus_tag="IVW63_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP7858407.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            79497..79859
                     /locus_tag="IVW63_000102"
     CDS             79497..79859
                     /locus_tag="IVW63_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858408.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            79862..80044
                     /locus_tag="IVW63_000103"
     CDS             79862..80044
                     /locus_tag="IVW63_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858409.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            80061..83492
                     /locus_tag="IVW63_000104"
     CDS             80061..83492
                     /locus_tag="IVW63_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAP7858410.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITAIAGVIAIIKNWGAITDWFSDLWKKFTDWLGDTWESIKESASSVWDGVKET
                     WSGFVDWVQEIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            83543..84280
                     /locus_tag="IVW63_000105"
     CDS             83543..84280
                     /locus_tag="IVW63_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP7858411.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            84290..86581
                     /locus_tag="IVW63_000106"
     CDS             84290..86581
                     /locus_tag="IVW63_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858412.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYDTAWTLDGGFNASFITAGEIVGITIRGTTLISDGTDYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYINDGDGNSLGIDGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDVDHFIIETSKPNVLVRWNLVAHRL
                     GYEDVRLKEDTAYDSTVLDQKRF"
     gene            86605..88287
                     /locus_tag="IVW63_000107"
                     /pseudo
     CDS             86605..88287
                     /locus_tag="IVW63_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737855.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        30039 a        14410 c        18771 g        25313 t
ORIGIN      
        1 atacctgatt acaaaaaaat aacttttata agttctataa cgttgattat atttttaatt
       61 cttattcttc tcgtcgtctt ggttccccga atttttggtt tgactcctta tattattgag
      121 gacaaagaaa tgagtccata ttatgcacaa ggaaatctga tatatgtacg accgaaaaat
      181 acaaatgaga ttttagtcgg agatattatt acatattatg aaaattcagg aaaaaaaatc
      241 tcgacgcgtc gcgtaatagc cgttgaaaac aaccacgaag atttttatac aaaagctgat
      301 acaaagactt atattgagcc tggagtagta aaaaagagaa atattatcgg tagtcccatc
      361 tttcagattc catatattgg actagtcctt tcaaaaacgg catttgcatg gattcagggg
      421 ttattcttta cgattgcttt ttgcctaaca ggaatcacag catggaatac ctttgtagag
      481 ttgaaaaaga agcggagacg aacacagaaa tttttgtaag aatgttaaaa acataaatgt
      541 attccagaga tccaacgact cttctgaaca tgaaacacga gaaaacactc atgcagcttg
      601 tagatttagt cagttgttcg tataatgtgt gaagaggagg agtagtatgc gcaatgaaat
      661 gatgcatcgt cctgtagtca aagaagaact attggatttt atgcgtaccc agcaaaaaaa
      721 attaccgggt gagctaggca aactggaaga agaagctcat gtagcagaag taccagttat
      781 tccccatgaa acagttgtat ttttgaaatt tttacttgga cagcttcagc ctgaacgaat
      841 cttggagatc ggagcagcta tcggtttttc atcaagtgtc atggccacga caatcggaga
      901 aaacgctcat gttacgacaa ttgatcgttt cgatgtcatg atcgagaaag ctaaaaaaaa
      961 ctatgaacgt ctaggactga cagataaagt gactttgctt gaaggtcaag cagcagatat
     1021 cttgccggag ttgtctggtc cgtatgactt tatttttatg gatagtgcaa aatcaaaata
     1081 tattgaattt ttacctgaat gcttacgttt gttaagaaaa ggtggcgttt tgatggtaga
     1141 tgacatcttc caaggaggaa cgatcttgct cccagatgaa gagattcccc gtggcaaacg
     1201 agctatccat cgtaaattaa atgaatttct tcgtgttgtg atggatcatc ccgatttgac
     1261 atcgacaatc ttgccattag gtgatggtgt gatcttaatg acaaaggaat cagaaacaat
     1321 cgagttgtga tacatgatta tggcagcctg tagataatcg attgaatcga gggctcaatt
     1381 cgaacttgat gtaaaagttt ctatatttgt aagtcaatta aaggatacag gaaatctaaa
     1441 taaacaggag tagcatgaag tcaatgtagc tcctgttttc aattgataac cttagaacag
     1501 ctgaaggaga atgtctcgtt ttaaaagatt gatttagtag ttgggccaaa ataattcatt
     1561 atttgctaat taaataacta tttcgtattg acagaagcaa tttaattatc tataattatt
     1621 gatgttccgc tgattcttgt catagtagct cagctggata gagcatccgc cttctaagcg
     1681 gacggtcggg ggttcgaatc cctcctgtga cgctaaaaaa ccgttagaaa ctgaggtttc
     1741 taacggtttt tctttgtttt ttgtgccaat attgtttgtt ttcaaaggca aataaaataa
     1801 aaaaacatcc ttatcgagta caattataag gagcaaaaaa ataaaactca tcagaaaaga
     1861 ggaagaagat atgacgatac tatctagaat tttagtgact ctagttgcaa ttgaattttt
     1921 ttatatcatg tatatcgaaa cggtgagaac tgattctgac acgacaagta gggtttttaa
     1981 aatgagtaaa gaagagttaa gcagaaaatc tgttcaaaca ttgtttaaga accaaggagt
     2041 gtacaatgga ctattaggag tgggactact ttatggagct tatctttctt ccgcatctaa
     2101 agaaatcaca agtatgctat taatatctat ttttttgttg cattatatgg cagtttgact
     2161 agcgatcgtt ggattttact caaacaaggt gggctagctc tgttggcatt gctttctatt
     2221 ttcttataaa tatagaaaaa ataagaattt atctaacagg aaactttgtg aaaaatatta
     2281 ctttatctca tgaaatatga tattctaatg aatggtattt tagaaaattt catgaaaaag
     2341 gagttagata ggtgttcaaa aattatgttt cctcactaaa aaaagaattt tcaggttatg
     2401 atctttcaag atttcagaaa gatcttttgg ctgggatcac agtagctgct gtagcattgc
     2461 ctttagcctt ggcttttggg gtatcaagcg gagctgatgc ggccgcaggt ttgattacgg
     2521 ctatcattgc cggtatcgtt attggcggtt tatcaggcgg tttttatcaa atatcaggtc
     2581 cgacaggtgc gatggcagct atcttgatgt ctattgcggc aacaaaggga atgcaaggtg
     2641 tattgcttgc tactttttta gcgggtctat ttttacttgc agcaggactt ttccgattag
     2701 gaacactgac ttcttttatc ccagcacccg taattacggg gtttacttca ggtattgcta
     2761 tcattattgc attaggtcag atcgataatt tatttggtgt tcactcggaa ggtacaaacg
     2821 ttattgaaaa actaagtagt tatcaaacga taggatttcc gataaacaca gcctctttga
     2881 tcatgggagg gctagtcatt ttagggatgt ttatctatcc aaaaaaatgg gcgaaacgaa
     2941 tgcctagttc gctgctggct atcattttgg caacagcagt tatgctattg ttccatttac
     3001 cagtagcaac tgtgggtaag attccacaaa cattgatcag tagtaatcgt ttgaatatgg
     3061 gagattttag cttttctgcc ttgcaacaag tggcagttcc agctattagc attgctttat
     3121 taggaatgat tgaaagcttg ctatgtggtg cttcggctgg ccgaatggca aataagccct
     3181 tagatagcaa tcaagaatta atggcgcaag gaattggaaa tctgttgctt cctttctttg
     3241 gcgggattcc tgctactgcg gccatcgccc gtacaagcgt ggccatcaaa tctggtgcac
     3301 aaactagatt agctggtatg atacatgcag ttgtcttact gctctccatg cttgtttttg
     3361 cgccagtgat gtcacagatt ccaatgccag cacttgcagg tgttttgatt gtgacggctt
     3421 ggcgtatgaa tgaatgggaa acgatcaagg agctatttac taataaatat tggtcagcag
     3481 ttctattgtt tatccttacg atgatttgta cagttatctt tgatttaagt attgctatcg
     3541 tgatcggggt gatcggcggc tgtgtatttt ttgttgtcaa aagcgctgct atcacgattt
     3601 cattagaaac gatcgattgg caaagaatgg ggctgccaga aacggaaaag ctgaataact
     3661 ggacagtagt gtatattagt ggtccactgt tttttatgtc ttcagaaaaa ctcaaaaata
     3721 aattggaaga actaaatcat cacgatggtg tcattttctc catgcgaggc gtaccaagta
     3781 ttgatttgac ggcacgtgca gtttttgatg aatttcaaga aaaagcagag caaagaggac
     3841 aaacgattat ctatacttcc ttgcagccag aagtagaaaa acaactttct cacttgtggg
     3901 aacatacatt cacgcatcaa catcaaacag ttgctcatgc gttgacagct ttacatgcga
     3961 aatatactgc aattagccat taaaacaatg aaaaagaaca gacaagactg taaactgaag
     4021 attttatggt cttgtctgtt ctttttaata ttgctgtaaa agtgaagcta gtacttgcca
     4081 gtcttgatgg ataacaggta caagggagcg attgtagaaa atagctgctg gatgaaaaag
     4141 tggaagaatt cgatagtttt tttctgacca ttcgtaggca tccttttgtt ctgttaattg
     4201 taagacaggc cctgtataga gttgaccatg atttttggta accgtatatt ctttgccaag
     4261 taaacgttga agaccaatgt ttccaagtgt cgcaattaat tttggctgga ccttcatcag
     4321 ttcgtaatcc aatattggtg catgcgcaaa tacttcggaa cgagtaggtg tccgatttgg
     4381 ataaacagtt tctgactgtt gtgtccgttt attgatccga tgagtcacgc gatacgggcg
     4441 gctccttaca gcactggtga tatacacctc ttctcgtgtt aagccagttg aagaaagtgc
     4501 ctgcatcaat tcttttccag cttgaccgct aaaaggaaca tgcgtatcaa tctctgtttt
     4561 ccctggggct tctcccacga gcatcagttt aggatgaaga ggtccttgcc cagcgataaa
     4621 tccttctaca ggacggccgt tcattcttaa agaagcttct tgtatcagtt cttttgggta
     4681 ttccatttat gctcctcctt tttcttttat tataagaata aaagaaacac aatgcgacta
     4741 ttttatttgg tagaactgtg aggatagaaa agcagaagta ttgcttgaat ttttgtttta
     4801 ctttttgatt ttaaatttag ttgactaacg gttgctgttc tggtaagcta gtactgttgt
     4861 aattgtggac tccacagcta caaccgctca gaacaagtaa taagcacagc atatgctgtc
     4921 acttcggatg gcgagtctaa gtatatcaga aggaggtgct ttatagcatg tacgcaatta
     4981 ttaaaactgg tggtaaacaa gtaaaagttg aagtgggaca agcaatctat gttgaaaaac
     5041 ttgacgttga agcaggagaa aaagttgttt ttgacgaagt tatcttagta ggcggagaat
     5101 ctacaaaagt aggcgctcca actgttgcag gtgcaactgt tgaaggtact gttgaaaaac
     5161 acggcaaaca aaagaaagtc gttactttca aatacaaacc taaaaaacat tcacaccgta
     5221 aacaaggtca tcgtcaacca tatacaaaag tggttatcga cgcgatcaac gcttaatagc
     5281 gtttgagaaa gaaggcctat atatgatcaa aggaacattt aagcgaaatg acgcaggtca
     5341 gatcgtttca ttcactttga ccgggcatgc tgatgctggt ccttatggaa gtgatatcgt
     5401 ttgtgcgggt gtttctgcgt tagcgatcag cactgtcaac gggattgcct cattagccgg
     5461 ttttgagccg attgttgaaa tgaatgaaga agaaggcggt tatctttata ccgaagtcac
     5521 ttcaggaatg acacaagaac aaaacaatat tgctgagatt ctattagaaa atcttttatt
     5581 aggattacaa tcgatagaag ctgaaaactc agaatatatc caaattaaaa caattaatga
     5641 taaataggag gtgcagacca tgttgttatc tatgaatcta caattatttg cccacaaaaa
     5701 aggtggcggt tctacatcta acggccgtga ctcagaatca aaacgtctag gtgctaaacg
     5761 tgctgatgga caaacagtta caggtggatc aattctttac cgtcaacgcg gtacaaaaat
     5821 ctatccaggt gtaaacgtgg gtatcggtgg agacgacact ttatttgcaa aagttgatgg
     5881 cgtagtacgt ttcgaacgta aaggccgtaa caaaaaacaa gtgtctgttt atccagtagc
     5941 tcaagaagct taattgaatc ttatgattaa agaggttgtg acaagacttt tgtcacagcc
     6001 ttttttgttt ataaaaataa aagttgtagt ggaggctacg aagtttactt tgtcttttta
     6061 cacttaatat ttttttgcca atttggaatc aggatgtttt gataactatc gttttcaatt
     6121 gatggaagct atattgtttg ctatcagtga aataattata tggtaaacag tgttcttttt
     6181 cttgtttcca ttataaaaat cgtatcggga tttttcgttc ttttaaattg aacatttcta
     6241 tctatccgcg tgttatcaac aaaacaaaat caggtaaata gttgacgaaa cagaaataaa
     6301 tacatagtat tatgttttga agcctaagta caatagtcta tagaaaagga gcgataccat
     6361 tggcaaaacg cattgaccga atttatatgt atgtcaaaga aaaaaccgct catttaacaa
     6421 aggcagaata tgatcaagga gtaacaacac aggaaattgc tgaagtgtta gggattcagc
     6481 gaacaaatag cagtaaagat ctgaatcagc tagtgcgcga aggaaaactg ataaagacag
     6541 acggacgacc agtacgttac atatatcaaa cactcgttac gcacgtaaag ccagttacaa
     6601 aacatgtagt cagttacaaa gaaacgccgg tctctgaaga aaaaaataca ctccaaatag
     6661 atactaagga tatctttgca aaaatcattg gagctaacgg cagcatgaaa aattcagtgg
     6721 aacaggcaaa agctgcgatt ttgtatccgc caagaggatt aaattgtttg attacaggac
     6781 ctaccggatc aggaaagact tattttgcac acgcgatgta tcattttgca aaagcgcatc
     6841 atgtaataga tgaggaaacg gaactgattg ttttcaattg tgctgattat gccaataacc
     6901 ctgagctttt gatgagtcat ttatttgggt acgcaaaagg tgcttttaca ggcgcagatg
     6961 aagaaaaaat ggggattatc gatcaagcgg atggcggtat gctgtttttg gatgagattc
     7021 accggttgcc gcctgaaggt caagaaatga tcttttactt tatggatcat ggaacttaca
     7081 gtcgtcttgg ggaaacaacg aaatcccatg aagcaaatgt acggatcgta ggtgcgacca
     7141 cagaagaccc aggttcttct ctattagaaa cttttgttcg gcgtatccca atcaatatca
     7201 aacttccggc ttttgaaaaa cgtcctgcaa atgagaaagt cgatttagta aaaatcatga
     7261 ttgcccacga agcaaaccgc acgcagcgaa agatttcttt gacagaagat gtagcaaaag
     7321 cattgatcgg cagtgtgacc tatggaaata taggacaatt gaagtcaaat atccagttag
     7381 tatgtgcacg aggatttcta aatcatatgc aatcacccga aatctcgatc acaatcgatg
     7441 atttgacaga agggattcgt agcggattga ttcaattagc aagcaaccgc agtgcaatgg
     7501 cagagctttc taaaatattg gagccaaaga taactgtagc accaaatgat acgatcatga
     7561 aaatccaatc ggactcctat gagttacctt ataatctata tgatatcatc ggagataaag
     7621 cagctttact gaagtcggat ggtttggatc aagaagcaat caatcatttc atttctacag
     7681 atatcaacat ccatctgaag tctttctata aagaccatgg tttttctttt aatgcagaca
     7741 gcaaattagc agaatttgta gatccgaaaa tcatagaagt gaccaatcag atttatgtaa
     7801 tggtcaaaag atctttacca tatgagtttc agcaaaactt tatttatgct atgagcttgc
     7861 atatcagttc ttttttgaaa aaaatcaact taggagaaga acggcatacg aatgataaca
     7921 tccgtgagat ggcttttgat tttccagatg aatatgctgt tgcgaaagaa gtgcgtagtt
     7981 atatcgaaac gtattttcaa gtggagattc cagaaagtga agactattac ttgaccgttc
     8041 tactcgtctc gttacgggca aatcaagcaa gcggcagaat cggtgtagtc gttgcagctc
     8101 acggaaacag cacagcaagc agtatggtcc aagttgtcca acagttgtta gatgcagaga
     8161 acgtacgagc agtagacatg cctttggata tggatccgaa aacagcattg gaccgaattg
     8221 aacgcaatgt acaagaagta gatgaaggaa gcggggtcat actcttagta gatatggggt
     8281 cccttgcgtc gtttaattcg caaattcaaa gagacactgg aattccagta cgtactgttg
     8341 atatggtaac aacttctcta gttttggaaa ctgtacgaaa ggtctcagta ttagggacag
     8401 atctagatat gttgcatgaa tcattgaaaa attttcgagg ttacgcagaa atatcttctg
     8461 tagaatctgt tcaggaagca aaacctattc ataagaaaaa agctgttttg gctatctgcg
     8521 catctggcga aggtacagca caaagaatca aagaattgat cgaacgagcg gtaaacaagc
     8581 gtcaagaaac agaattagaa gttctagctt tgtcgattgt ggaagtgaaa gaagaactgc
     8641 cagttatcca aaaagaatat cagatcatag ctactactgg gattactgat ttgaatatcc
     8701 aagccccatt tattccttta gaacgtttta ttgatcaaaa tatcgaagtc attttggatc
     8761 agttgctgat ggaatcagaa ttggaggaaa ctgaattcat ctccctagat gaagagtcag
     8821 ctaaaaatac gtgtgttgag tttatctctg ataacttcat ctttattaat ggtagtaagt
     8881 taatcgatcc aatgtggcaa ttttctacac aaatctctca gacgacggga atcggcgatg
     8941 aagaatatgg attcaaaatc aacctagtga tgcacacagc aggaatgatc gaacgtatta
     9001 ttcggaatga accattgact gtggaagaaa acgaattgac aaatacaacg aatgatcctc
     9061 tttatagcca attggcagcc tcagttgttc tgttggaaga tcagataaaa gtaaaagtgc
     9121 cgatagaaga aatgtattat ctgctacgtc tagtccataa tcagttagat aaaaaagaat
     9181 acactgtgcc atgaatacac aaaaacgata cacttttata gtgtatcgtt tttgtgtatt
     9241 ggttaagaat cctttaaatt caattagtgt atcgtaaaaa agttggcacg ctttttgctt
     9301 atagtagtgt gtgctaggag gtggttgttc acacagaaat gataggggtt tctgtgaagt
     9361 agtgaggaag aaggagtttt gcagatggat attcgattgg cacgtataga tgatcgttta
     9421 atccacgggc aagtcgcaac agtttggtcg aagcaaacag gtgttgaacg tatcattgtg
     9481 atcagcgatg tagtcgctca agataaattg agaaagtttc tactaaaaga agctgcaccg
     9541 ccggggatca cagcaaatgt aataaccgtg cagaaaatga ttcaaatcta tcatagtgga
     9601 ttattatcac gagcaaaagt gatgctttta ttcaccaatc cccaagatgt tgaagcggtt
     9661 gtccgctgcg gtgtacagtt gaagtcgttg aatatcggcg gtatgagttt tactgaaggc
     9721 aaatcaatga ttaccaattt tgtttcagta aatcaacaag atattgattc ctttcgttac
     9781 ttgaacagtc aagaagtgga gttagagatt cgaaaagtac ctgctgacag gaaaatcctt
     9841 ttgatggaac tactagcgaa aatcaaaaag gtgtagcaag aatggttgtt ggaaaaggtc
     9901 aaataattct gttgtaatgg ttagcaatta ttaatatttt tgaatttgtt acaacaaaag
     9961 taaataggag gtataaatat ggtagggatt atcctagcaa gtcatggaca atttgctgaa
    10021 ggaatcttac aatccggttc aatgatcttt ggcgaacaag aaaacgtcaa agccgtgatt
    10081 ttgaaaccaa gtgaaggtcc agatgacttg agagccaaat tggaagaagc ggttgcttct
    10141 tttgataatc aagacgaagt gttattctta gttgatttat ggggcggaac accgttcaat
    10201 caatcaaaca cattattcga agagcacaaa gataaatggg caatcgtcag cggtttgaat
    10261 ttaccaatgt tgattgaagc ctacgcatca cgcttttcaa tggaatctgc tcatgaaatt
    10321 gcagcacaca tcattgaaac agcaaaagac ggtgtaaaag taaaaccgga agaattagaa
    10381 ccggcagaag caccgaaagc agcagttgaa gacgcacaac ctaaaggagc acttccagaa
    10441 ggaactgtgg tcggagacgg aaaaatcaaa tatgtattag cacgtgttga ctcacgtctg
    10501 ttacatggac aagttgcgac agcttggaca aaagcagtgc aaccaaaccg tattatcgtt
    10561 gtttcagatg cagtatcaaa ggatgatctg cgtaagagac taatcgaaca agctgctcct
    10621 ccaggtgtaa aagcaaatgt tattcctatt agcaaaatga tcgaagtagc aaaagaccct
    10681 cgttttggaa ataccaaagc attgctttta tttgaaaatc ctgaagacgt attgacagct
    10741 gttgaaggtg gcgtagacat caaagaatta aatgttgggt caatggcgca ttcggtcggt
    10801 aaagtcgttg taagtaaagt attgtctatg ggacaagaag acgttgaagc gtttgagaag
    10861 cttgaacaaa aaggtgtgaa attcgatgta cgtaaagtac ctaatgattc acgcgataac
    10921 atggatgata ttttgaaaaa agcaaaagct gaattagcaa aagcgtaata aataatatta
    10981 aaatttatag gaggcttatc atgtctatta tttcaataat tttagtcgta ttagttgcct
    11041 ttctagctgg tatggaaggt attcttgatg aatttcaatt tcatcaacca ctagtggcat
    11101 gtacattgat cggtttagtt accggtaacc tcgaagctgg tatcgtactt ggcggtacgc
    11161 ttcagatgat cgctttaggt tgggcaaata tcggtgccgc tgtagcacca gatgctgcat
    11221 tagcatcagt agcatcagca attattttag ttttaggtgg acaaggtgtt aaaggtgttc
    11281 cttctgcgat cgcgattgcc gttcctttgg ctgttgcagg gttgttctta acaatgatcg
    11341 tacgtacaat cgctgttcca atcgttcatt tgatggatgc ggctgctgaa gaaggaaaca
    11401 tccgtaaggt tgaaatgtgg cacatcattg ctgtatgttt acaaggggtt cgtatcgcgg
    11461 tcccagcagc agcgttgcta tttatcccag cacaaactgt gcaatcattc cttgaatcaa
    11521 tgccagcatg gttaacagat ggtatggcta tcggtggggg aatggtcgta gctgtaggtt
    11581 acgctttggt aatcaacatg atggctacaa aagaagtatg gccattcttc gttattggtt
    11641 tcgttgtagc tgcaatttct caattaacat tgattgctct aggtgcttta ggtgttgcat
    11701 tagctcttat ttacttgaac ctttctaaaa tgggtggttc atcaaataat ggaggcggaa
    11761 gcaactctgg tgacccttta ggcgacattt tgaatgacta ttaatcttga aggaggaaaa
    11821 taaaatggca gaagaaaaaa tcaaattatc aaaaaaagat cgtttagctg ttgcgtggcg
    11881 ctctaccttc attcaaggtt catggaacta cgaacgtatg caaaacggtg gctgggcatt
    11941 ttctatgatt ccagcaatca aaaaattata caaaacaaaa gaagaacgtt ctgcagcatt
    12001 aaaacgtcac ttggaattct ttaatacaca cccatacatt gcttctccaa ttttaggggt
    12061 tacattggct ctggaagaag aacgtgcgaa tggcgcgcct gttgatgatg tagcgattca
    12121 aggggttaaa gtaggtatga tgggtccttt agctggtgtt ggtgacccag tgttctggtt
    12181 tacagtacgt ccaatgctag gtgcactagg tgcttcatta gctatgggag gaaatatcct
    12241 tggaccaatc atcttcttct taggttggaa cattattcgt tgggcattca tgtggtatac
    12301 acaagaattt ggctacaaag ctggttctaa aattactgat gacctttctg gcggattgtt
    12361 acaagacgta acaaaaggtg cttcaatttt agggatgttc gtattagctg cccttgtaca
    12421 aagatgggta tcaatcaaat tcttaccagt tgtatcaact gtaaaattag ataaaggtgc
    12481 ttacatcgaa tgggataaat tgccttcagg tggtgaagga atcaagagtg catttgaaca
    12541 agttaataat ggcttagccc tttctcctga aaaggtaaca acattacaag acaacttaga
    12601 ccaattgatt cctggtttag ctgcattagg attaacattg ttatgtatgt ggttgcttaa
    12661 gaaaaaggtt tctccaatcg ttatcatcct tggtttattc gtagtcggtg ttgttggaca
    12721 cgtcatcgga cttttataat ccataaaaat atagctcggg cgttgtcccg agcttttttt
    12781 atatagtata ctgttcataa acaaatatct ggagggagaa aatggttcaa tcaatcaata
    12841 caaaagtaga cttggtaatt gatgctactt cgtttacggg tctgacagat tacgggcaaa
    12901 tcatgatagg taataatggt tttgagtttt accatgcgcg agatagacgc aaatatatcc
    12961 aaattccatg ggaagaagtg gattatgtac tagcatcagt catgctaaag ggaaaatgga
    13021 ttcctcgata tgccattcaa acgaaaaaaa atggtacata cacattttct tccaaagaac
    13081 ctaaaaaagt gcttcgtgcg atcagagaat atgtagatga agatagaatg gtacaatcat
    13141 tgagtttctt tgatgtagtg aaacgtggta ttcgtagtat gtttaaacgc aagtaaaaaa
    13201 taaagaaaac ttctaagagg aggttttctt tattttttta ctttgcagaa gaaaatatga
    13261 aatagcaaaa ccaattattt gtccccttta aatcccatat gctaaaattg attagcaaag
    13321 aaggaggtta tattatgagt tggttatgga cattgattgt tggagccgtg atcggagcaa
    13381 ttgcaggtgc gatcaccagt aaaggaaatt cgatgggctg tgtaacgaat atcattgctg
    13441 gactagtcgg ttcaagtatt ggacaagcga ttttcggcga atggggacca aaagctgcag
    13501 gtatggcact tattccatct attttaggcg cagtgatttt ggtagcagtt gtctcatttt
    13561 tctttggaaa acgatcataa gtttttacaa aatagtaaac taaaaggagt tgcagcgaga
    13621 ctgtgactcc tttttggctt tatttattta aaataaaaag aagttttccg gaaattttta
    13681 tttaactgtc gtgtacgaag aaaagtttgc tataatggaa aaaagcgtgc aaagaaagag
    13741 ggagtttcat tatgatgcta cgtgtagaaa aattgcgcaa aaaaatgcaa gaagaaaatt
    13801 tggattcatt tttggttacc agtccgtaca atcttcgtta cttaacgaac tttacaggta
    13861 cgacaggatt agctgttatt actttggaaa aagcattttt tattactgat tttcgttata
    13921 ccgagcaggc ggcagcgcag gctcaagggt ttgaaattat taaaaatgtc ggacctattt
    13981 ttgatgaggt agcaaactta gtacgcaaag aagaactgca ctcattagct tttgaggaaa
    14041 caacagtctc atttttagaa tattcggttt tagaagaaat catcgatgcg gaattagtac
    14101 ctgtttcaca gatgatcgaa gaactcagag aagtgaaaga tgaagaagaa atcgctatta
    14161 tcgaaaaagc atgtcatatt gcggatatgg catatgatca catcctgaaa atgatccaac
    14221 cgggcatgac tgagattgaa gtcgcaaatc aactagactt ttatatgcgt tctcttggcg
    14281 cttcaggtgt ttcttttgat acgatcgttg ctagcggatt gcgttcggct atgccgcatg
    14341 gtgtagcaag caaaaaaatc atcgaacaag gtgacttgat cacattggac tttggttgct
    14401 attacgaagg gtacgtttcc gatatgacac gtacattcgc tattggtgat cctggggaaa
    14461 aattaaaaga aatttatcaa atagtcttag atgctcaatt agcagttatt gatgctgcaa
    14521 aaccaggaat gactggtgtc caattagatg cagttgctag agattatatt tcaaaacatg
    14581 gttacgggga agcatttgga cattctacag gacatgggat cggtttagag atccacgaag
    14641 gaccaaacgt ttcttctcgt gcagaaaagc aatttgtacc aggaaatgtg atcactgatg
    14701 aaccagggat ctacttacca ggaatcggtg gagtacgtat tgaggatgac ttgttgatca
    14761 cagaagatgg aaatcgtgtg ttgactcgtt caccaaaaga attgatcatc ttatagtttc
    14821 atcaatagaa gaagtaagcg taaaaatcag tgttcacaga ctttgttata gaaaatcact
    14881 cgatttaatg atacactata gaagaacttt taagctgtaa gagataataa agttgggtgt
    14941 tttctccaat tcatagcagt ttgcagctga tcggcggcag ttttcttacc acgtgatcac
    15001 tatgccgcat catagagaat tcggatgtat ctcgtgctta ggcaaaggga ggaataaata
    15061 aatggcagat gaaaaaaatt tgattttaaa cgcaaaccaa gatttaggag agatcgtgat
    15121 cgctcctgaa gtcatcgaag taattatcgg gattgcagct tctaaagtag aaggcgtata
    15181 cggaatgcgc ggaacttttg ccagcaatgt cactgaatta ttaggacgtg cagctcacgg
    15241 aaaaggtgtt tacttagcaa acgaggaaga tggcttgaaa gtagatcttt actgttatct
    15301 agaatatggt gtttcagttc ctaaagtagc aatggaaatg caggaacggg tcagccagca
    15361 agtccttttc atgacggata tcgatttatc tgaagtcaat atccatgtag tagctgttgt
    15421 tcctgaaaaa ttagaacaac caacaatcga agaacttttt gaagacgaag aggaagagaa
    15481 tgaataaaga attatcaaga cacgagattc gggaaatggc attgcaggct ttatttccat
    15541 tagacttcaa tgcagaccta acaaaagaag atgcgatttt caacgcaatc gaattagacc
    15601 accgcgacat gatcaacgaa gatgaatcag agtttgttcc tgtttatctt gatacgctag
    15661 ttggcggtgt ctgtgcaaaa aaagatgaat tggataaagt gattgaaaaa catttaaaaa
    15721 acaattggca catcaatcgg atctcaaaaa tggatttggt gatcttgcgt atcgcgattt
    15781 ttgaaatgac ttatgtgaca gatgtaccag cggctgttgc tttaaatgaa gcaatcgagt
    15841 tggcaaaaac atttagtgat gaccgttcac gtaaattcgt caacggtgtt ttatccaatg
    15901 tattgaaaga attagaagct ggggcgtaag tcctagcttt tttctatgaa tcatcataaa
    15961 cctgttataa atcgggaaaa ttctatggta gaatgaaaac acaaaaaata tctgggagtg
    16021 gttagatggc agaattgatt aacggaaaag aattagctga aaaaatgcag gcagagattg
    16081 ctgaaaaaat ccaaaaattg aaagataatg gtatccatcc cggattagtc gttttattgg
    16141 taggggaaaa tccagccagc caaatctatg taagaaataa agaacgtgta gcaaaagaaa
    16201 tcggaatcca ttcattggta gagcgttatc ctgagacgat ttctgaagac gaactacttg
    16261 cagaaattga aaaatacaat caagatccta gttttcatgg tatattggtc caattaccat
    16321 tgccaaagca tatagatgaa gaaaagatcc tgttagctat ccgccctgaa aaagacgtag
    16381 acggttttca tccgatgaat ttaggcagac tccttgcggg taaaccggac aagattcctt
    16441 gtactccata cggcatcatg aaaatgtttg aagcttattc tatcgatccg gcgggtaaac
    16501 gagcagtagt tatcggacga agcaatatcg tcggtaaacc gatggctcag ctactcttga
    16561 tggcagatgc aactgttact gttgctcatt ctaaaaccga aaatctggct gaactggcac
    16621 aagaagcaga tattttagtc gtagcaatag gacgtggaca ttttgtcaca aaagaattcg
    16681 taaaaccagg tgctgtagtg atagatgtag ggatgaatcg tgatgctaac ggtaagctga
    16741 tcggtgatgt gaaatttgat gaagtggagc ctattgcagg ctggatcact cctgtgccaa
    16801 agggtgtagg gccaatgact atcacgatgc tgatgtatca aaccgtaaaa tctgccgaag
    16861 cttttggagc aggtgaatag atggcacaag aatatttaac tgtcactaca ttaacgaagt
    16921 atttgaaaag aaaatttgat gccgatcctt atttagaacg cgtatattta acaggcgaaa
    16981 tatcgaattt ccgtttacgt gccaatgccc atcaatattt cagcttaaaa gatgaccatg
    17041 caaaaatatc tgctattatg ttcaaaggag cattccaaaa attacgattc cagccaaaag
    17101 aaggaatgaa agtccttgtc gttgggcgta tttcattata tgaagcggga ggttcttatc
    17161 aaatctatgt agagcacatg gagcctgatg gaataggtgc tttatatcaa gaattggaag
    17221 aacgaaaaga aaagctgatg aaggaaggcc tttttcaagg gcctaaaaaa atgctgccac
    17281 gtttcccaaa gcgaatcgcg gtccttacca gtccaagcgg agcggttatc cgcgatatca
    17341 tcacgacggt gaaaagaaga tatccaattg tccaattggt tttgttccca acagttgtac
    17401 aaggaaacca agcagcggac aatgttgtca ggaatatcca gagagtagaa gagatgggca
    17461 atttcgatac aatgatcatc ggtcgtgggg gtggttcgat tgaggattta tggccgttta
    17521 atgaagagcg ggttgctcgg gcgatttatc aagctaatac gccggtgatt tcatctgtag
    17581 gacatgaaac agataccacg atcgctgatt tagtagcaga tgttcgggct gccactccaa
    17641 cagcagctgc agaattagct gttcctgttt tgtcagaaga gttgatgcgc attcaagaac
    17701 ggcaagctag attgcagcag gcgtttgtac gccagatcca gcgcaaacaa gaacggttcg
    17761 agcgtgctcg acgttcctat gtatttcggc agcctgaaag attgtatgaa ggtcagacca
    17821 tcaaattaga ccagttgaaa cagcgattat atcaagctac acagcaaatt tatcatgcga
    17881 aagaaaaaca aacgatcgca ttaagccacc aattggaaca agtggctccg ctttatcgag
    17941 ttaaagcagc tcgccaagaa actgcttatc tagaaaaacg cttagaagag aaaatccaac
    18001 aatatatgaa acaacagcag cagcgttttg ctcaagctgt tcaatctctt gatttgttga
    18061 gtccattgaa aatcatggga agaggctaca gctatacgac gttaaatgat caagtagtaa
    18121 aaagtgtcac cgagattcat caaggggatt tgctgacgat ccattatcaa gatggaatcg
    18181 ttaaaggaca agtacaagag atagacaaag gagaataaaa atatggaaaa tccaactttt
    18241 gaagagtcac tgcaagaatt agaaaaaatt gtcatgcagt tagaacaagg agacgttcca
    18301 ttagaatcag ctctagattc gtttaaacga ggaatggaat taagcaaaca ttgccaagat
    18361 acattagcta aagcagaaga gaccttgacg aaaatgatga cagaatcaaa tgaagaagtt
    18421 gattttgacg gaaacgagga aagctgagat gagattaact gacttttcag ctattcatct
    18481 acctgctgta gaaaaagaaa tcttgtcttt tttagatgag catacaacgg atagaggact
    18541 ctatgatgcg atgagttatt cagtgaaagc aggcgggaaa agaatacgtc ccttattact
    18601 tttaacggcc gttgcttcct ttgatgagcc tattgatgtt cccgtctatc aagtagcagc
    18661 tgctttagaa atggtgcata cgtattcctt gatccacgat gatttgcctg cgatggacaa
    18721 tgatgatctt cgtagaggaa aacctaccaa tcataaagta ttcggcgaag cattagctat
    18781 attggccgga gatggtttgc ttacaggagc attccagcta atcagtatgg cacacttagg
    18841 taattctcct aagcttctgc tgcttcagca attagctgtt tgtgcgggat cacaaggtat
    18901 ggttgctggg caagctgcag atatcgaggg cgaatcgaaa aagctttctt tagaagaatt
    18961 agcatttatt catgaaagaa agacagggca tttgattcgt tatgccttgc tggctggtgg
    19021 catattagcg aagcaacctg aagaaatctt attgctactt caacgattag ccgaacattt
    19081 aggtttagct tttcagataa gagatgatct actcgatgtg attggtacaa cgaaaacatt
    19141 agggaaaaca gctggtaaag atgaacgtat ggaaaaaaat acttacccgc gtttattagg
    19201 cctagaaaag acacgtgagg cgttggagat tgagctgtta tccgccaaca agatcataga
    19261 caaattagaa gaggacgttt tttcttttga tggcgggctg atgcgccaga tgatcaagca
    19321 atttgatgtg gagaaatgag ggaaagaatg gaaaaagaac gcgtagatgt attagcggtc
    19381 aaacaaggat tatttgaaac aagagaacaa gccaaacgtt cagtgatggc tggtttgatt
    19441 tacaacgaaa aaaacgagcg gtttgataaa ccgggagaaa aaattccagt gagtagtgaa
    19501 ttaagagtca aaggtaaaaa acttccttat gtttctcgag ggggattaaa attagaaaaa
    19561 gcactcaaag catttgatct atctgttgaa ggaaaaacat tgttagatat tggtgcatcc
    19621 actggcggat ttactgatgc agctttgcaa aatggcgcaa aaatgagtta tgctttagac
    19681 gttggctaca atcagctagc ttggaaaata agacaagatc ctagagtcgt cgtaatggaa
    19741 agagtgaatt ttcgttatgc aaaacccgaa gactttacct taggaattcc agaagttgct
    19801 gttatcgatg tttcttttat ttcactaaaa ctgatgctgc ctccattaca tgctatttta
    19861 aaagaagagg gagaagtgat tgctttaatc aaaccccaat tcgaagcagg cagagaagct
    19921 gtagggaaaa acggaattgt tcgtgaccct cagacccatc aaaaagtttt agaagacatt
    19981 ttgtcatttg cggcacaagg tggatatgat gtgctggaat taagttattc tccgatcacg
    20041 gggggagaag gaaatatcga gttcttggct cacttgagga aagtacccga aagcggaaca
    20101 atcaattcag ctattaatat ggcagaagtg gtttcaaatg cacacgaaca gtttgaccat
    20161 aaataaattg taactgtgaa aatcaagtga gaagtatgcg gattcttctt tattatacca
    20221 aggaaataag ctatcattga ttaagaagaa tatgctaagg agcgaagacg taatgagaaa
    20281 aaaagatcgg catcgtttga ttactcgatt gttgagtgag caagatatcc gaaagcagga
    20341 agaatttgtt gaaatcctga aaagcaaagg aatatctgtt actcaagcta cgatttccag
    20401 agatataaag gaactgaaac tgatcaaggt accggcttca gatggcggct accgttatag
    20461 cataccagct gaaacaaacg aagatgtaaa tactaaattg gaaaaactat taaaagacgc
    20521 tttcgtggca gttgaccaaa tggaaaaatt tgttattttg aaaacattgc cgggaaatgc
    20581 ttcggcagca gcaaatttga ttgataaacg ttacaagaaa gaattatttt cgattatcaa
    20641 tgatgacgat aatgttttga tgattacacg aactgaagac caggcagttt tattgaagaa
    20701 agacttcctg cattaccttt aagttgagga gcgaatgtga tgctacaaga aatcagtatt
    20761 actaactttg cgattattcc ggaattgcgg ctttcttttc acgaaggaat gaccgcgctg
    20821 accggagaga ctggtgcggg taaatccatt attatcgatg ctttaggtct gttagcagga
    20881 ggaagaggtt caagcgatta tatacgtcaa ggagcagaaa aatgtgtgct tgaagggttg
    20941 tttgaactac caaaacaaga aggattctct gaactgatgg ttgaattagg gatcgaaaca
    21001 gatgaggaca atctgattgt tcgacgggat atgtccttaa ctggaaaaaa tgtttgtcga
    21061 gtgaatggtc atattatcac attagctaat ctgagaagaa tcggcagtta tttagtagat
    21121 atccaaggac aaaacgaaca tcaggaactg ctccagcctg aatcacatct tgctttattg
    21181 gatcgttttg gagatgtagc tttccaacag aagaaaaaga gttatcagca agaatatatc
    21241 tcttatcgtg agctggaaaa aagggtacga aaagtgcagc aaaatgaaaa atcctatgtt
    21301 cagagaatag atatgctcca tttccagcaa gaagaaatag ctgctgctga tttgcaagtc
    21361 ggagaagaag agaaattaaa agaagaaaga gaaaaactta gcaattatca aaaaattgct
    21421 gatggattag ctgcaggtta cggagcactg acgaataatg aacaaaacag tgtagatggt
    21481 gttggcttgg ccgtttcaga actgcaaggg atcgcccatc tagatgtgga gtatgaagca
    21541 atttatgaaa atatccaaag tgcttactat ttgctgcaag atgcaatcgg cgatatgagt
    21601 cgtcagattg atttattgga gttagatgag agtcgtttag aagaagttac gcaacgttta
    21661 gaattaatcc gacagttgaa acgtaaatac ggcgaatcca ttgagtcaat attggcttac
    21721 tatgacgaaa tcaccgaaga gctagcttct tctgattttt cagaaggtca attggacaaa
    21781 atgaaagagg aactagagca aaaagagctt ctacttcagc aacaagccgc agatcttcat
    21841 gaagcgcgta aaaaaatcgc aaaagaattg gaaaaatcca ttctgcatga attgaaaagt
    21901 ctgtatatgg aaaacactga gtttgaggta cgtttcttaa aagaagaaaa tagacaattg
    21961 aatcatgatg gatttgacca aatcgaattt tacattacga ccaatccagg agagccactg
    22021 aagcctttgg tgaaagtcgc ttctggtggc gaactgtctc ggatgttgct tgctttgaaa
    22081 actatttttt cttctgagca aggtgtgaca agtattattt ttgatgaagt ggatacaggt
    22141 gtgagcggaa gagttgcaca ggccatcgca gataaaattt ctcaaatatc gaaatactct
    22201 caagttttgt gcatcactca tctgcctcaa gttgctgcag tcgccgacta tcaatattat
    22261 attgtgaaag cagtgattga tggacgtacg caaacttctg tttcagagtt gaaaacaaaa
    22321 gaaagagaag aagaaattgc acgtatgctg gctggaagtg agattacaaa actcacactc
    22381 gaacatgcaa aagaactatt gaaactcgca aaaaggacct gagccacctc gcagtggttc
    22441 aggtcctttt cagcagctga tagctatatt ttatttttac atgacactca ttacagcagt
    22501 caatacaaca gatccaatcg ttaaaatcag cattgtccaa atgacaaatt ttgttacttt
    22561 agcaaaagta cttgtttgtt ttttttcacg cattgttttc aacctcgtca ttaattagtt
    22621 gattcaagtg tacaatcttt tttccatttc cacaagaggg cttttttata aaaacttccc
    22681 tttttttaaa taataggtag ttacgataca aataaataat gttaatagaa ctagccatat
    22741 aaaggcatca tccctttcag caataggtaa cttaatgttc attccataga tactgccgac
    22801 gattgtcggt atagttaaaa taatcgttaa agaagttaaa attttcataa tattattcag
    22861 attattcgat acgattgctg aaaaagtctg attcatttgt tctactagtt ttaattgaat
    22921 gcgagaagta gtcattgcct gctctgtttc caccaataca tcacgtaaat gatttttcaa
    22981 agcatgattt tcttggaaaa gtttattttg cgctagttct ttcaatgcat ctaaattagc
    23041 agaagtcgct tctctgaaat aaacgaggct tttttggata tccatgattt gataaagttg
    23101 tttgttttca gtggatactt gaagtttggc ttccaaagta tcgcattgag attgaagcgt
    23161 agctaaataa ctgttgtaag agagtgtgac ctgccaaatg aattgaaaga agatattgag
    23221 attaggcgaa atatcacttt ttgtaaaggt ctggctaaag actttcttta aaaacagtgg
    23281 ttcatgattc gtaattgtga taagcttctt tttgggcgtc aaaataatag agagcgggta
    23341 tgtatccact tgaaaataac cgctaggact tgttttagca aaaggatatt gtaacaataa
    23401 taacgctggc tttgtcaact ttgattgatt gaattcttct gtacgggaat tttctgcatc
    23461 gtccaatatg gaagtgatgt aatctgacgg aatttcaaat tgatgtgtca gctgatgaat
    23521 ctcttcttga ttaggacgtt ctacacaata ccagatcgtt tggtcagttt cctttccggt
    23581 attacgcagt ttctcattat ctaatgtaaa atatttgatc atgattttcc tcctgttgcc
    23641 tgtttctttt attataacgg atagggaatt ggaatacatg gaatgtgttt gtaagatata
    23701 gaatataact gcataaattt aaataaaatg aaacagttgt gtaaagtata tacagtatac
    23761 ttgaagcaac gataaaaaag gagtttacgt tcatgggcac attcacacca cttatcttgt
    23821 tttggtatat ttacccggta atcgttttgt ttggttgcca atttcttgta aaattatttt
    23881 cgttaaatcg tcgttttaaa ataaaagccc ctgatttggc gattcctttt ttgtggggcg
    23941 gtatgcatgc attgtctaga aatacaggga caatttctat cttaccgttt ttctttattt
    24001 ctgttttgct aatgggaatt tgtattgctg ttttccaagc atattattat gaagaaatta
    24061 tttatccgcg ttatttcaag atgacttggc gtttggtttt tctgttgaca atcgtcttgt
    24121 acgctgtctt gatcattgtg aacatacttt cttacctatg aaaaaaatag aaaagctgta
    24181 aaaagtcttt taaaaggctt tttgcagctt gatttttaaa aaaatgttta tgaataaaaa
    24241 aagttgttcc cggatttccc agaaaaggtg gtagaaagtg ggggattgtg gtagactaat
    24301 tttagttagt ggaggaatgg ggggctttca atgttgatgg gtgaattcca acataatatt
    24361 gatgcaaaag gacgtttaat cgtgccctca aaacttcgtg aagaacttgg cgaaaagttt
    24421 gttctgacac gcggattgga tggctgtctt ttcggctatc cgatgagcga atgggaaaat
    24481 ctggaagcta aactgaacga aatgccgttg gctaaaaaag acgcacgtac ttttgtgcga
    24541 ttcttctatt cggctgccac tgaatgcgaa cttgataaac aaggacgaat caatataccc
    24601 agcacgttaa gaaattatgc agctttgaca aaaggttgcg tagtcatcgg tgtatctaac
    24661 cgaattgaaa tttgggatga gacacgatgg caagattttt ctgcagcagc agaagagaac
    24721 tttgacgaaa ttgctgaaag tatgattgat ttcggactat aagaatagga agaggctgac
    24781 taatgactga aacatttcaa cactatacag tcatgttgaa agaaacggta gatggattga
    24841 acatcaaacc ggatggcgtt tatgtagact gtacactcgg cggtgccgga catagtgaat
    24901 atttattaag ccaactaagt tctaaagggc atctgtatgc gtttgaccaa gatcaaaaag
    24961 caatcgatca cgccaagctg cgtttagctt cttatgtcga acaaggtatg gtcacattta
    25021 tcaaagcgaa cttcagagaa ttagaagaac gcttgagtga gcatgtagat aaggtagacg
    25081 gcattttgta tgatctaggg gtttcctctc ctcagctaga tgaagcagaa cgtggattta
    25141 gttatcatca agatgcaccg ttggatatgc gcatggatca gtcagctcct ttatccgctt
    25201 atcacgtaat taatgaatat tcctaccatg aattagtaaa gattttcttc cgctatggcg
    25261 aggagaaatt ttccaaacaa attgctcgtg aaatcgaacg agtacgaaaa acaaaaccaa
    25321 tccaaacaac tggtgagctt gtcgaaatca ttaaacaagt catcccagct cccgcaagaa
    25381 gaaaaggcgg gcatcctgca aaaagaattt ttcaagctgt gcggattgca gtaaatgacg
    25441 aactcggtgc cgaagaggcc tctttagaac aggcaatccg gttattgaaa gtcaatggaa
    25501 gaatcagcgt aatcacattc cattcattgg aagacagaat tgtcaaaagt atgtttaaag
    25561 aatatagtac ggtacaagat ctaccaccgg gacttcctgt catacctgac gaattccaac
    25621 cagaactgaa agtcattact cgtaaaccaa tccttccttc agaggaagag ctaacagaaa
    25681 acaatcgatc acgcagtgca aagttacgta ttgcagaaaa aataagaatg aaagaggagt
    25741 agaatgatgg cagaattaaa gaaaatgcaa gattacgaat atgatttacc tgaattggtg
    25801 gatcagccgg aacaacaaat gcctgattct tcttcgaatc aagaaatcat tcttccacaa
    25861 tcaccggcaa aacgattaaa gcagatttct gctttggaaa aaattgctgt ggcaagcgtg
    25921 gcgattgcta ttgttgcttt atgtgtttta acagttatgc tgcgcacaaa tatcagcgga
    25981 gctgaaaaag aaatcacgtc aatacaaaca gaaatcaatg ataaaaagca agaaaaaacg
    26041 agtttagaac aagaaaaaaa cgaactttct cgtactgaac ggattaaaca aatcgcagaa
    26101 gaaaaaggat tgtctattaa tgacgacaat ttaaggaaag tgaagtaaat gagtcttaaa
    26161 aataaaattc ggcggtttat ggaaaagaaa aatctaaatc cgatgaacaa tcgcaaaaaa
    26221 gtaggtatca ttttatttgc tacgagtatt ggattgttct ttttatttgc cgtccgtttc
    26281 tcgtatatcg ttattggagg tcatgttgct ggtacctcat tagctgaaaa aacaaaacag
    26341 ttgtaccaag gaagtgaagt agtaaaagca aaaagaggaa cgatttatga tcgtaacggt
    26401 gtggcgctcg cagaagatgc ctcctcttat tcaattaaag cgatactctc aaaaacatat
    26461 acctctgggg ataaaaaact gtatgttgaa gaaaagaatt ttgataaaat agcagaaatc
    26521 ctgcataaga atctttctat agacaaaaaa gatgcactga atattttaga ggacggcgca
    26581 aaaaaagagc tgtatcaagt tgaatttggt agctatggga aaaatatctc ccaagaaacc
    26641 aagcaaaaca tcgaagcgga catgaaaaaa gaaggtgtcg ctggtcttta ttttgtcgac
    26701 catcaggctc ggatgtatcc aaatggcgtc ttttcttctc attttattgg atacgcagtt
    26761 ccagacaaag atgagaatgg cttagttggt aaactaggtt tggagtctgc ttacaatgat
    26821 atcttgagcg gtaaagatgg taagattatt tatcaaaaag ataattttca aaatcctctg
    26881 ccaggtacag tggcagaaga agaaaaagct gtcgacggac aagatatcta cacgacttta
    26941 gacagcagac tacaaagtta tttagaaaca ctgatggatc aagtaaatga agaatatcag
    27001 ccagaagaat tgacagcagt cctgatgaaa gcaaaaaccg gagaaatctt ggcaatggga
    27061 caacgaccta ctttcaatcc tgaaacaatg gaaggattga ctggaaaaga tgctatctgg
    27121 cgtaatttct tggtacaaga tagttatgaa ccaggatcaa ccatgaaagt tttcactact
    27181 gcagctgcta tcgaagaagg agaattcaac gagaatgaaa ccttccaatc tggaaaaatc
    27241 caagtagaag atgctacgat caatgaccat gactttggtg aaaaaggtgt gctgaccatg
    27301 cgtcaagctc tttcatggtc aagtaacgtc gggatggtca tactggaaca gcgattaggc
    27361 ggacgatggt ataactattt acaaaaactg ggatttggac aaagtactca ttctggatta
    27421 gatgatgaag taaacggtgc tttacctaca ttaaatattg tcgaccgagc aatgagtgct
    27481 tatggacaag cggtaggtgt gacgaatttc caaatgatga aagctttcac ttctattgcg
    27541 aataacggta caatgattca acctcgatat atcagcaaag tggtggatcc ccaaactgga
    27601 gaagagcgaa caactcaaac agaagttcta gggcaacctt tttcaaaaga aacaacagaa
    27661 aaagtccgtg aatatatgag agatgttgtc gaaagcgaaa actacggtag tgcttatggt
    27721 gtatatagtg tacctggata caatgtatcg gcaaaaaacg gaacagccca aatcgcttct
    27781 gatacagggg gatatcaaac aggagataca gcctacctgt attcgattgt ggagatggtt
    27841 ccttctgaag atccagacta tgtcttgtat ctaacaatga aacaccctaa gacatatgat
    27901 cgaatggcat tggctaaaat cgcaaatcca ttgatgaaac gggcaatgga ttttaaagaa
    27961 actgaagaag attcagatac agaaacaaaa acagaaaaag tatccgtagc cgattatcgt
    28021 aatcttgaag cggacgttgc agcagctgat gctcaaaaaa gtggactgca acctgtagtg
    28081 atcggtaatg gtaaaaaagt acaaaaacaa tctactgcca acggtgatca gttgatctct
    28141 ggagaaaaac tgatcctata tactggtggt gataagctga tgcctgacgt aacaggatgg
    28201 tcaaaagcag atatcatgaa gctggggaaa atcctcggta ttgaagttag ttttgatgga
    28261 gatggttatt gtgtcaaaca agaacttgct ccatatgaaa aaatcactga agacaaactt
    28321 agttttactt tagaagaata agaagagaaa taggagagaa aagagcatgg aatggacaca
    28381 agcattgatt cccattgtca gcagttgtgc aatgacaatt gccgcaatgc cgctatttat
    28441 tggttatttt caaatgaaaa agcaaggtca ggcgattcgt gaggagggac caaagtggca
    28501 caatagcaaa gccggaactc ctacaatggg cggcttagtg tttctgatcg gctctatttt
    28561 gacaggaatt tgggttggag cttggcaaaa acagctaact cctactcttt tcatcttgct
    28621 ttttgtatta gcgttatacg gagtaatcgg ctttcttgat gattttataa aaatattcaa
    28681 gaaaagaaac atgggactga actcgaagca gaaattgatt ggacagattc tagggggaat
    28741 catcttttat cttgtttacc gttctgaagg ttatccaggt gtattgaatt tcttcggact
    28801 agatctacct ttaggaatca tttatggtat tttcgctctc ttctggcttg ttggattttc
    28861 aaatgcagta aatctgacag atggcatcga tggattagtt gctggcttag gaagtatctc
    28921 ttttgcagct tacggtctaa ttgcttggca tcagcatcag tatgatgtat taatcatttg
    28981 cttaagtgtt ttaggaggtt tactgggttt cttcgtctac aacagaaaac ctgccaagat
    29041 ttttatggga gatgtcggtt cattagcgtt gggcggactt ttagcggcaa tttctataat
    29101 gctaaaccaa gaatggacat tgcttttgat tggtttgatc tatgttatgg aaacagcaag
    29161 tgtgatgctt caagttactt cctttaagct tacaggaaaa cgaattttta aaatgtctcc
    29221 aattcatcat cactttgaaa tgtgcggatg gtcggagtgg aagattgata cagttttttg
    29281 gttgatcagc attgtgactt cgttgatcac attatggatc gtttggtagg agatgacggg
    29341 aaatgaaaaa aatatcaaca tatgaaaata agaaagtgct tgtcttagga ctcgcaaaaa
    29401 gcggagtaag tgcggccaaa ttattacatg aattgggcgc acttgtcacc gttaatgatg
    29461 gaaaaccttt tgacgaaaat ccggaagcac aagagctgct ttctttaggg ataaaagtaa
    29521 taacaggtag tcatccaatc gaattgttgg atgaagaatt ttcattgatg gtcaaaaatc
    29581 cagggattcc ctacagtcat cctttagtag caaaagccca agaaatgggt attccggtaa
    29641 ttacggaagt tgagctagct tacgaagtag cggaatgccc aattattggg attacaggaa
    29701 cgaacggaaa aacaacgaca acaacgatga caggactact actgaatgca ggagcagatc
    29761 aaggaattgc acgtttagcg ggtaatattg ggtatccagc aagtggtgta gcgcaagaag
    29821 caaaatcaga agataaaatt gtgatggaat tgtctagctt ccaactcatg ggaatcacag
    29881 atttccgccc tcatatagcg gtgattacca atatctatga agcacatatt gattatcatg
    29941 gtacaagaaa agaatatgtc aaagctaaat ggaaccttca aaaaaacatg acagaaaaag
    30001 attatctgat ccttaactgg aatcagtcag aactacaaga attagcgcaa agaacaaaag
    30061 cacgcgtact gcctttctcg acaaaagaag tgttggaaga cggtgtgtat gctgacgatt
    30121 actcaatata ctataaaaaa gaaaaaataa tggaaatatc tgaacttggc gtaccaggta
    30181 agcataatgt agaaaatgca ctagctgcta tttctgtagc aaaattgtat ggtatatcaa
    30241 atgaagctat acgagaaacg ttgcattttt tccatggcgt accacatcgt acgcaatatg
    30301 taggagaaat ccaaggcaga aaattttata atgattcaaa agcaaccaat attttagcga
    30361 ctaaaatggc tctaagtgga tttgaaacgt ctaaggtcgt gttattggct ggcggattag
    30421 acagaggaaa tacatttgat gaattaattc cttcattaaa aggaatcaaa gcaatggtcg
    30481 tatttggcca aacaaaagaa aagttgatgg atgctggaaa aaaagcaggc atcgagacaa
    30541 tagtaacagc cgattctgta gaacaagcag ttcctttagc attagaaaac agtacagatg
    30601 gtgatgtagt tttattatca ccagcgaatg ccagctggga tcaataccca aattttgaaa
    30661 ctagaggaaa cagattcatg gaagctgtga accgattaaa atagaaaaag tagaagcgag
    30721 cgataaaaaa tgaaaatttt ggttacaggc ggaggaacag ggggacatat ttatccagct
    30781 cttgcctttg tcaattatgt aaagactcaa gaaccgaatg ctgaattcat gtatgtggga
    30841 gcaaaacgag gtctagaaaa caaaatcgtc cctgatacag gaatgccttt ccataccttg
    30901 gagattcaag gatttaaacg aaaaatttcc atgcataaca tcaagacggt ccgattgttt
    30961 cttaagagta tccgtcaagc aaaaaaaatc ctcagtgatt ttcaaccaga tatcgttatc
    31021 ggtactggag gatatgtttc cggagcggta gtgtacgctg cagccaaaat gggtattcca
    31081 acagttatcc atgaacaaaa cagtgtacca ggtgttacca ataaattttt aagccgatat
    31141 gtggatcgga tcgctctttc atttaaagat gcggcttcct tttttcctga aaacaaagca
    31201 gttcttgtag gtaatcctcg agcacaagaa gtagcagata ctaaaaaatc agatattttg
    31261 aaaacatttg atttggatcc agaaaagaaa acagtcttga tttttggcgg tagtcaagga
    31321 gcacttaaaa tcaatcaagc agtatcagtt tttttaagtg aatatattcc ttcttcttac
    31381 caagttttgt atgcttcagg agatagatat tatgaagaga tcctaaataa aataaatcct
    31441 gaaatacaaa atattagtgt ccagccttat atcaaaaata tggcagaggt catggcttcc
    31501 agtgatctgc tggtggggcg tgctggtgca acttcgatcg cagaattcac agctctgggg
    31561 ttaccggcag tgttggttcc cagcccatat gttacgaatg atcatcagac taaaaatgca
    31621 atgagtcttg ttcacgcagg agcagcaaaa atgattgcag ataatgaact aacaggtgaa
    31681 tcactaagtc agacagtcaa cgaaatcatg ggtgatgaag aattgcaaaa gcaaatgtgc
    31741 cgagcttcta aagaacaagg aatccctgat gcttcaaaac gtctttatga cttagtaaaa
    31801 caaataatca aaaaataaag gcggtggtct tagtgagtaa gaaaaaagaa ccaaaaaaat
    31861 tgtctcatcc gtcttctgat gaaaacaatt tgactccttg gcaaaaggct aaccgaaaat
    31921 atctggcaga acaagagatg aaaaaccaag agccaaaaaa agaagacata acattagata
    31981 cacccctttc agattctgaa gaagaaaaaa cggttcaaga ggaacagcaa gaagaaagcc
    32041 agtccgagaa aaaaatcgaa ttttttgaag agatcaagca aaagaaaaac ggtggaccat
    32101 ataacggttc ttttttgaac cggctgccca atttaaaaag tcaacggcac aaagtactat
    32161 ttcgtcggtt agctttgatc atcactgtat tgggtatacc gctgattttt ttgatctatt
    32221 atgtttctcc ttatagcaaa ttacaagcag ttgcagtatc aggcaataag acagtcaaca
    32281 gccaagaaat catctctgat acaaaattgt cattaggaga aaatgtttgg ggacagtatt
    32341 ttcatcgatc tacttatatc gatcgcctta aaaaagcaca gccaagaatc gaaacagcaa
    32401 atatacattt caaagggatg aatgaattcg atttggatgt aacagaatat aaagagattg
    32461 ctttgatcgc aaaaaacaat caatactacc cagtgattga aaatggaaca gtattagatg
    32521 aaaaagtagc aaatcctaca aaaaatctcc ctatcttgga agagttcaaa gactctgcaa
    32581 aaatcaaaga attaacaaag caatacaatc agttatcatc agaattacaa aaagcaattt
    32641 ctgaaatcaa gtacacgcca agagcaagca ataaaaatct gatccaattg aatatgaatg
    32701 acggcaatca agttattgta aatatcaata atcttgcgaa ccaaatgaaa tattattcgc
    32761 aagtagccaa agatatggat gaaaaaggtg tgatcgacat ggaagttggt atcttctcgc
    32821 atccttacgg tagcactcaa gaaacggaag aatcgggcca atcggaagaa acaactgaaa
    32881 gtgaagaaaa tgcggatcaa acaaacgaat caagtgaaga ggcagaaacg caaaaagcac
    32941 aaacacctgg atcgtctagc acaaacggat catctgattc aaatgattca agtgaaacaa
    33001 gtcaaataga agataatcca agtacaactc cgtcaagttt aaatgaaaat tgataaaaca
    33061 actttaaaaa gtaagaatgt actttctaaa aaccagtaat ttatggtaga attggaagca
    33121 gtgaatatat ctattaataa gtatatttta aaacggacgc tagttgttcg cttgtatatg
    33181 gaatagtaag taggagggaa tcccattcat ggcaaaaaca ggaatgtatg taggccttga
    33241 tattggaacg acatctgtta aagttgtcgt ggctgaatat atcgacagcc aaatgaatat
    33301 tattggagta ggaaacgcaa aatcagaagg gattaaccga ggcattatcg ttgatatcga
    33361 taaaacggtc caagcgatac aacgagcagt acgacaagca gaagaaaaag caggtatcca
    33421 gatcaaaggc gtaagtgtcg gtttgccagc aaacatgctt gaagtagaaa attgccaggg
    33481 aatgattgca gttaacggag attcaaagga aatcaccgat gaagatgtca gaaatgtggc
    33541 ttcagctgcc cttgttcgtt caatacctcc tgaacgtcaa atcgtgtcaa tattgccaca
    33601 agattttact gtcgatgggt tcgagggaat caaagatcct cgtggaatga tcggcgtaag
    33661 attagaaatg tacggtctgt tgtttacagg acctaaaacg atcatccata acatacgtaa
    33721 atgcgtggaa aatgccggat taatcgtcaa cgaaatggtg attactcctt tagcgctgac
    33781 tgaatcaatt ctttctgacg gagaaaaaga ttttggtacg atcgtcattg atatgggtgg
    33841 cggccaaaca acaacggctg ttatgcatga taagcaattg aagtttacca atcttgacca
    33901 agaaggtggc gaatttgtca ctaaagatat ctctattgta ttaaatacgt catttaacaa
    33961 tgcagaagcg ttgaaaataa actacgggga tgcataccca gaacggacat caccagatga
    34021 agaatttcca gtagatgtga ttggtcagtc agaaccagtg aaagtcgatg aacgctactt
    34081 gtcagaaatt atttcagctc gaatggaaca gattttcaac aaagcaaaag atgcattgga
    34141 ccaaatcgaa gcattagagt tgccaggtgg cgtcgtattg acaggcggag ctgctagtct
    34201 tcctggtgtt gtggacttgg cacaagaaat cttcggcgta aatgtaaaat tgtatgttcc
    34261 aaatcacatg gggctgagaa acccggtatt tacaaatgta ataagtatcg tggattattc
    34321 agcaaacttg agtgaagtgt atcaattggc aaaaattgct gttacgggtg aaacctcagc
    34381 agctcgtcaa atggtagttg aacaagaaac aacaaacaca tatgagagct atgaagcacc
    34441 tgaagaaaca atctacgatg agccggaacc aaaagagtcc ggagaaaatg taaaaaataa
    34501 aatcaagggt ttctttacaa atatttttga ttaattcatc ctgggaggaa taagatatgg
    34561 aattctcaat tgataataat atcaatgacg gcgcagtaat caaagtcatc ggagtcggtg
    34621 gtggcggtgg aaatgctgta aaccgaatga ttgaagaaaa cgttaaaggt gttgaattca
    34681 ttacagccaa cacagacgtg caagcattaa aaaattcaaa agctgaaaca gttatccaat
    34741 taggccccaa atatactcgt ggtttaggtg ctggttctca gccagaagtt ggacaaaaag
    34801 cggcagaaga aagtgaacaa tccttacgcg aagctttaga cggtgcagat atgattttca
    34861 tcactgcagg aatgggtgga ggaaccggta caggtgctgc accaatcgtt gcaggtatcg
    34921 cgaaagaatt gggcgcattg actgttggtg tcgtgacacg tccattcact tttgaaggac
    34981 cgaaacgtgg ccgttttgct gcagaaggta tcgctcgttt gaaagaaaat gtggatacat
    35041 tattaattat ctcaaataac cgtttattag aagttgtaga taaaaagaca ccgatgcttg
    35101 aagctttccg tgaagcagat aatgttttac gacaaggtgt acaaggtatc tctgatttga
    35161 tcacagcgcc aggttacgtt aaccttgact ttgctgacgt gaaaacagtg atggaaaacc
    35221 aaggtacagc attgatgggg atcggtgtgg ctagtggaga agatcgcgta gtagaagcaa
    35281 cgaaaaaagc aatctcctct ccattgcttg aaacatctat tgatggagct gaacaagtac
    35341 ttcttaacat cacaggcggt ttggatatga cattgttcga agcacaagat gcttcagata
    35401 tcgtagcaaa tgcagcaact ggcgatgtaa atatcattct aggtacatct atcaatgaag
    35461 aaatgggcga tgaaatccgt gtgacggtca tcgcaacagg tatcgatgaa tcaaaaaagg
    35521 aacgcaagtc tagccgacca gctagacaag cacaaatgca atcacctgct caaaagactg
    35581 tattagatat ggatcaagct aaaccaactt cttcagaaga agaaaacagt tttggcgatt
    35641 gggatatcag acgtgaacaa aatgttcgtc ctagagttga tgattccaat tttgacaata
    35701 tcgaaaaaaa agaatttgat acattcaacc gcgaagaaac aaaatctcat ggcgatgatg
    35761 aattaaatac gccaccgttt ttccgtcgta aaaaataaag gagaggaaga gcacatgatt
    35821 gctgacaact tgcagaaaat caagcaagaa attcaggatt cgtgtgctct tgttcatcgt
    35881 gatccgaaag aagttacatt agtagctgta acaaaatctg ttgaatccgc tcaagctgaa
    35941 gaattggtta gagctggcgt tatgaattgt gcagaaaacc gagtagataa attattagaa
    36001 aagaaacaag atttatttga ttttcctgaa ataaagtggc atttaattgg taatttacag
    36061 cgcagaaagg taaaattgat tgtaaatgaa attgattact ttcatgcgtt ggacagttta
    36121 agattagcag aagaaatcca gaagcggtta gagaaagaat tatcctgttt tattgaagta
    36181 aatgtttctg gtgaggaatc aaaacatgga atttcaccag atgagctttt accgtttgtg
    36241 gaatctttag ctgcctgcac aaaaatcaag gttgttgggt tgatgactat ggcgcctaaa
    36301 gaagcttctg atgagcaaat ccataaagtg tttggtacgc tgaaagaatt gcgtgatctt
    36361 gttcaagcaa aaggttatgc ccatgcacca tgtagtgaat taagtatggg gatgagtcaa
    36421 gactttcaaa ttgcgattga agaaggtgca acatttatcc gtgtaggaac agcgctattc
    36481 aaagacgaat aaaggaggaa caaaaatgcc gcttttaaac agaggagcaa ttgctaattt
    36541 tttcggatta gctgatgagg aagagtacga ataccaagat tatcctgaaa caacaaaaaa
    36601 ggctgtacag ccaactaaaa aaaatacaac acagaatcaa tcaactcatt ctgtatctgc
    36661 tgcgaatact catgaaaaac aaaaaacggc gacttcacgt cctgtaacgc atgaaagtat
    36721 tcagccggct gaaaagaaaa aagtaattga actacatcaa tcacctacaa aaactgtagc
    36781 gaaagaaaga acagcttcaa gaacctctac acaacctaaa gcaaatcttg ctggaaaaat
    36841 cactgtaatg gaaccaagag cttattctga agctatggcg attgctaaac gaatcattgc
    36901 tggagaagca accttagtga attttcattt agtagaagaa aaacaagcga gaagaatcgt
    36961 tgattttcta acaggaacag tttatgcact agatggagat atcaaacgtg ttggagatga
    37021 gatttttctt tgtacaccga ctgggatgga gattgacagt tcaaccgctc aatcttttgc
    37081 agatgcgaat ttgtttgatc tgtaagagga ggaactacga tttatactat tgcactatta
    37141 cttcatttac ttcaacgggc agcctatttc tatagcatta tcttgatggt atatgcattg
    37201 ctctcttggt ttccaggcgg gtatcaatca gggctaggac gattattagc taagatctgc
    37261 gaaccgtata tcagtttgtt cgatcgtctg cctttgagga ttggaccctt ggatttcaca
    37321 attttagggg caatcctgat cttgaactta gccgtacaag gtttagcaca gatcgttata
    37381 tggataactg tccatttagt ttattgattg aagcaacaaa atctttattc tcagaataga
    37441 taggagggga aaattttgga tgcaaatgta taccagcact ttcgggcaga tgaacgtaca
    37501 tttatcgatt cggtaggcga ttggattgaa caggttcaag gacaatatgc accctatctg
    37561 accgaatttc ttgacccaag acaatcctat attttagaaa cactgattcg acaaagcagt
    37621 gatttgcgtt tcatgtttta tggcggatat gaacaggcag aaagaaaaag atgtttgatt
    37681 ttccccgatt attacgaacc tgtagaggaa gattttgaaa cagcattgta tgaaatccat
    37741 tatcctagca aatttgccag cctaagtcat gggaaaatcc ttggaacttt agtgggaacg
    37801 gggatcaaac gctcttactt tggcgatatc atctcggacg gtgatcgctg gcaagtattt
    37861 attgcaaatg aggtggatca ttttgttgct gcacaagtaa caaagattgg aaaggttgct
    37921 gtacgcttgg aaccaatcaa atacacagaa atgattatgc cgaaagatag ctggacacaa
    37981 gaaagaggaa cagttagttc catgcgacta gacagtgtga tctctgagat ttataatatt
    38041 tccagacagc ggtccaagca gctgatcgaa gctggtaaag taaaagtgaa ctggacagaa
    38101 aatacaagac ctgattttgt acttgaacta ttagatatta tttcagtcag aggttatggc
    38161 agagtccaga tccaagaact tgaggggaag acgaaaaaag aaaagtacag ggtactgttc
    38221 ggtgtattac gtaaataaaa taaaaaggtg gtttactcat ggctttaact ccattagata
    38281 tccaaaataa gacattcccg acaaaaatgc ggggatataa tcaagacgaa gtagatgatt
    38341 tcttagattt agttgttcgt gactatgagg aattgactca aagaaatcga gaattagaaa
    38401 aagcagtcaa acattctgaa gaaaaacttg agtacttcaa tgaattaaaa gatgctttga
    38461 accaatcaat catcgtagct caagatacgg ctgataaagt aaaaacaagt gcaagcaagg
    38521 aatccgaagt gatcgttact tctgcacaaa acaaagcaga tgagttagtt gcgaacgctg
    38581 aaaaacgtgc acatcaatta acaactgatg cagaagaaaa agcaagaaaa atcttgacag
    38641 atgcaacaga aaaagcaaga cagcttgcga cagaaactga agatcttaag aaaaaaacac
    38701 gagtattcca tcaacgtatc agcttgatgc ttgagtctca attagaacaa gtgaaaagtc
    38761 cggaatggga tgaaatttta caaccattct ccagctacgt gactgacagc catgaagtga
    38821 tcaaagaagt tttagcaaaa cagcttgaca atgaaaatga tactgatgta aactcagaca
    38881 caggagtcat agaagcacct atgacggcat ttgatacaca ggctattgat atctcgatcg
    38941 tgcctggtga aaatgaaaac gagtagaaca gaaaagcact ttgttattct taaagcgagc
    39001 cgatgagagt ggaagttcgg taagacactg catggtgaaa gatcctctac ttgagacctg
    39061 cttttccgaa attagagtaa gaagcagcgg ctgacctcgt tattggtcac agagagtttg
    39121 cactagatag atgcaactaa atttgggtgg taccacggca tgttcgtccc ttgcggctga
    39181 acatgctttt ttgtgtccgg aaaacaaata aaggagtgta tggttgaatg aaaatgaaag
    39241 aaaccttgca attaggaaaa acaaaattcc ctatgcgtgg taatttgcca aaccgagaag
    39301 gcgagtggca aaaagaatgg gaagaaaatc gaatctacca aaaaagacaa gagttgaacg
    39361 aaggaaaacc tagctttgtt cttcatgatg gacctccata tgccaatggt aatatccatt
    39421 taggacattc attgaataaa atcagtaaag acattatcat tcgttcaaaa tcaatgtctg
    39481 gctatcgtgc accatatgtt ccaggatggg atacacatgg attgccgatt gaacaagtat
    39541 tggctaataa aggcgtgaaa cgtaaagaaa tgtccatggc agaatacttg gaaaaatgtc
    39601 gtgaatatgc actttcccaa gtagataagc aacgagcaga tttcaaacgc ctaggagttg
    39661 caggagattg ggaacatcct tatgttacat tagatccttc ttatgaagct gcacaagtac
    39721 gcgtatttgg taaaatggct gaaaaaggct atatttacaa aggattgaaa ccaatttact
    39781 ggtctccgtc aagtgagtct tctttagcgg aagctgaaat tgaatataaa gatgtaaaat
    39841 ctccatctat ttttgtagct ttcaatgtca aagacggcaa agatattctt gatgaagata
    39901 cagcttttgt catttggacg acaacaccat ggacattgcc agcaaaccaa ggtattgctg
    39961 taaatccaaa atttacgtat gtattggtgg aagccgatgg ccgtaagttt gtcgtagcga
    40021 aagatttgct agaaacagtc caatcagaaa tcggttggga aaatgtaaca gttctaaaag
    40081 aatttgctgg acaagaaatg gaatatatga ctgcaagtca tccattctat gaacgtgaat
    40141 cacttgtgat tttaggcgat catgttactt tagacgctgg tactggatta gtccatactg
    40201 ctccaggaca tggggaagat gactatatcg ctggtagcaa atataaacta tctgtagtgt
    40261 cacctgtaga ctcaaaagga ttgtttacag aagaagcacc tggatttgaa ggtatctttt
    40321 atgacaaagc aaatcctatg atcactgatc tattaaaaga aaaaggagct ttgctgaagc
    40381 tagatttctt tactcatagt tatcctcacg attggcggac gaaaaagcct gtgatctatc
    40441 gggcaactcc acaatggttt gcatctatcg ataaattccg tcagaatatt ttggatgaag
    40501 tagaaaaagt agagtgggtt atcccatggg gtaaaacacg tttgtataat atgatccgtg
    40561 accgcggcga ttgggtaatt tcccgtcagc gtgcatgggg agtaccactt ccgattttct
    40621 atgctgaaaa tggagaagca atcatcacac cagaaacaat cgaacatgtg gcaaaattat
    40681 ttgctgaaca tggatcaatt atctggtttg aaaaagaagc gaaagaactt cttcctgaag
    40741 gatttaccca cccaggttct cctaatggcg aatttacaaa agaaaaagat atcatggatg
    40801 tctggtttga ttctggttct tctcatgaag ctgttttacg tcagcgacca gaattatcat
    40861 tcccagcaga tatgtattta gaaggatcag accaatatcg tggctggttc aactcaagta
    40921 tcacgactag tgtggctatc aatggtgtag caccatacaa atcagttatt tctcaaggat
    40981 ttgctttaga tggtgaaggc cgtaagatga gtaaatcttt aggaaacatc attgcaccag
    41041 aaaaagtgat caaacaattt ggtgcagata tccttcgctt atgggtatct agtgtagatt
    41101 atgaagcaga tgttcgtgtt tctatggata tcttaagtca agtggcagaa gtatatcgta
    41161 aaatcagaaa tacgatgcgt ttcttattag cgaatacaga agatttcgat cctaaaaaag
    41221 atactgtttc gtacaatgat ttacgttctg tagacaaata tatgaccgtt cgattgaacc
    41281 aagtaatcaa agaaatccga gaagaagggt acgacaaata taacttcatg catatttacc
    41341 gtacagttat gaacttcttg acggttgatc tatcgtcatt ctacctggat tttgctaaag
    41401 atgtagttta tattgaagca gaagatgatt atcaacgtcg ttgcatgcaa actgttttct
    41461 atcaaacagc tgtagctttg acaaaattat tgactcctat cattccgcat acagcagaag
    41521 aaatctggtc attcctgaaa gaagaagagg agtacgttca gttaagcgag tttcctggtt
    41581 atgaagagtt tgcaaaccaa gaagaattga tggatacctg gactgctttc atggacttcc
    41641 gtgataatgt cttaaaagca ttggaagaag caagaaacag caaattgatt ggtaaatctt
    41701 tggaagcaaa actaactgtt tatccaaaac aacaagttcg tgaaatgtta aaagctttgg
    41761 atgcagatat tgcacaatta ttgatcgttt caccagacta ctttgaagtt atggcagcag
    41821 atgaacaagt gccagataac gctatggtat ttgatgatgt tgctattaca gtggaaaaag
    41881 cagacgggga aacttgcgat cgctgtcgcc aagttcgtaa agatgtagga gtagatgaaa
    41941 aacttcctca tctatgcggt cgttgtgcaa aaatcgttga agacttctat cctgaagctg
    42001 tagctgaagg attcgaagaa aagtaaaagg gaaaaggggg tgtgacatgt tctttgtcac
    42061 accccctttt gttatcaatc gtttaatttt ccacgttcac gataccagtt atctggttgc
    42121 cagatccatt cgaatccgtc tttttcaagt agttcgaaag ctgctttagg tcccattgat
    42181 ccagctttgt agttgggaaa atccggttgt gtttggtccc aagcttttcg aatgacatcc
    42241 acgatatgcc aagattgagc gacttcttcc caatgagaga agttcgttcc atcaccattc
    42301 aacgcatcta atagtaattt ttcgtaagct tctgggctat tttcaaccat ttctgcacta
    42361 tttctaaatt ccaatttgat tggttccgtt tcaaatcctt gccctacttc tttcccattc
    42421 aaggataaag aaaatccttc agttggctga atatagatcg ttagaacatt aggtggaagt
    42481 gtcgtatcgt cacatggttc atcgacagat gttttgaata cattaacagg aacttgtttg
    42541 aatacgatgt tgatccgagt ccctttttca gtcaaacgtt tgcctgtacg tacatagaaa
    42601 ggaacacctg accaacggaa gttatcgata gtgaatttgc ctgcgacgaa tgtttcagtc
    42661 tctgattgag catccacttt gtcttcttcg cgatagccct tgaattgtac accatccaat
    42721 tcaccttgag catattgccc gcgaacgaag ttttctaaca cttcttcttc gttataaatg
    42781 cggatagctt tcaatgcttt gatcttttct gtacggattt ctttttcgga aaatgctact
    42841 ggcggttcca ttgcaagtaa tgctacaacc tgtaaaatat gattttgcac catgtcttta
    42901 agtgcgccac tatgatcgta gtagcccccg cgatcttcta caccgaggtt ttcgccaaaa
    42961 gtaatttgga tattgtcgat atagcgattg ttccattgag cctcaaaaat attattggca
    43021 aaacggatag ctgagatgtt ttggatcatt tcttttccta aataatgatc aatcctgaaa
    43081 atatcttgtt ctgggaatac ttctctgatt tgctggttca attcaaaagc agactggtaa
    43141 tcagaaccga acggtttttc tatgatcaaa cgattgaagc cattttttgt cataatattt
    43201 tgtgatttca aatgagaaac gatcgttcca aaaaattgag gtgccatagc caaataatag
    43261 acacggttac cgtttaattg atagtgtcca tctaatcggt cagacaattc ttttaatgtc
    43321 tgataatgcg ttgaatcatt tacatcatgg gattgatagt aaaaatggct tgcaaaggta
    43381 gttgcttctt catctgaagg attcaatgca cggattgttt ctttgacaac ttcacggtag
    43441 tgctcatcgc tccagggacg gcgagcggtt ccgattacag caaaatgctc gcctaaattt
    43501 ccttttctgt aaaggcggaa caaagacggg tacaatttac gctgggctag gtcacctgta
    43561 ccgccgaata tcgtaaacaa tacatttttt tcattagaca tgtggataca ctcctttata
    43621 ttttatcgac aaaaatcgtg ctggccgcct taaagctgac ggggattttc tttctatcat
    43681 tttggatagt gatcggtcct tcataagctg cgatgtcaac gatctcatat tcttcgttga
    43741 tattcaggtc aatagtgact aagtaatcca acaattcttt ttcatcaagc actcgtgcga
    43801 tacgcacttt tgtaccgaca ggataggact ccaatgtttg tcggcgttct tcatggacaa
    43861 cttcctcttt tttaggaatc gatcctccat gaggacaatg ttcaggatga ttcaaatagt
    43921 tttctaaatg atctgcaaga tgttccgaag tcacatgttc caatacttca gcatcatcat
    43981 ggacttcatt ccagctatag tctaaatgtt caactaaaaa aacttcccat aagcgatgtt
    44041 tgcgaatcag actgctagct ttttgcagtc cgcttgcagt caattgtaca ccttgataag
    44101 gggaatgttc tacaagctct tctttcacaa gtttagaaat catttcactg acagatgcag
    44161 ctgagacatc tagactagat acgatttgtt tattgttgac tttcgttgta tctccaccta
    44221 gttctaaaat gattttcaaa taatcttctc gatttggtgt catattcgat catcctttca
    44281 tggtaaaaaa ccatcattag taagtgtaac aaaaaaaacg ttaattgact atttttctaa
    44341 ataaaaaaca aaggattttt agacgttttt acaacaaaaa acgaaagatg atagagaaga
    44401 ctcattcttt cgtttataaa ggatatatat atacattggg agggatctat ttttcagata
    44461 acaacttata tgaagtgtct gcagattcgt cataaagagt ttgttcggga taagaaaaga
    44521 taagataaaa accatactga tcacgtacga ctaaacgata ttcatctatt tctaccacag
    44581 atgtgccaag agactgaccg ttgatcaaaa acgtgtaatc agatgtaatc tgtaattgtt
    44641 gtttttgctg gctatcacta aagaaccatg taccttgata ctttgagagt ccttctgact
    44701 tttccgcttg ttttttcttt ttcaagtaaa taaaacttga gagaacggta atgagtgaac
    44761 caagaaaata gatcattttt tttatcacca aatcactcct ttatgagaaa ataatcgcat
    44821 agacatattc tttcttcttt atttcattgt accgaataaa agctaaaatt tctctaagac
    44881 tttcgactgg tttttttact gtttttctac aaattatgat aggatacata gtaggaagaa
    44941 aggtgacata atttgaagta tcagcaagtg gaaatagctt tttttattga ccgcccgaat
    45001 cggtttatag cacattgtat gaaaaaagac ggagaaataa ttattgcgca tgtcaaaaat
    45061 acaggtagag gaaaagaggt cctgatacca ggcgctgaag tggctattgt atttgctcct
    45121 ggacctaaac ggaaaaccgc ctatgatctg attgctgtaa aaaagaaggg tgactggttt
    45181 aatatcgata gtcaattgcc taatcggctg gcaattgatg gtattttaga cggcacgatc
    45241 cttttaccag gattaactgg tccatttacg gtatacaagc gtgaagtaac ttatcttcac
    45301 tccaaatttg atatttattt agagacggtg gtcggacaaa aagcatttgt tgaagtcaaa
    45361 ggtatgacac ttgaaaataa agcgattggt gcttttcctg atgcgcccac actcagagga
    45421 ttgaaacata taggagaatt aacgtatgcc gcacaagatg gttatgccgc ttatgtcttg
    45481 tttattgctc agttcgaaca tcttcatctg gcaacgatcc atgaagaaat gcaaccagca
    45541 ctagctgata tggttcgaca tgcgcagcaa agcggagttc aaatcctcgc ctataattgt
    45601 caagtatcgg cagatgaggt aactgtcaag caggccattc catttgatgt agatatccct
    45661 tttgaagatc ctatacaata gaaagaaggt aaaataatga tcaacttagg tattatcgga
    45721 acaaattgga ttactcatca atttgtccaa gcagctttaa gcacaaaaaa atatgaattg
    45781 acagcggtat attctagaca tttggaaaaa gcacaggaat ttggttctca ttatgaaggg
    45841 gatatcgaat tcgcaacaga tttgaagact tttttcaata ttactcatat ggacaccatt
    45901 tatattgctt ctccgaatag tcttcacttt agtcaagcta agcaagcaat tttggcagga
    45961 aaaaatgtga tagttgaaaa gccagctttt tcgacgccaa aagaaatgga tgaaatcatc
    46021 catttggcaa atgaacacaa tgtgtatttt tttgaagcag caagaaatat ccatgaatca
    46081 ggttttaaaa agattgccga ttacttacca ttaaaagacg agataatcgg tgcaaatttc
    46141 agctatatga aatattcttc gcgctatgac caagtattag atggagaaga accgaatatc
    46201 ttctcgactc atttctcagg tggtgcattg atggatttag gtgtttacct tgtatatgca
    46261 gctgttgctt ggtttggaat gccaaaagaa gtccattatt tcccaagaaa gatttctact
    46321 ggtgtagatg gtcttggatg ggggatctta cgttatgaga attttgatgt atcgatccag
    46381 ccaggtaaaa tcggtgattc ttatttaccg tcagagattt attttgactc aggaacgcta
    46441 gtgatgaatg gagtcaatgc aattgaacaa gcacaatttc atgatcgcgc gcataaagaa
    46501 atcattgatt tggcggtaac agctgcagaa aatccaatgg cagatgaagc agaggatttt
    46561 gccaatgtca tggctcatcc gaaagatcca gcttggggat tgttgtatga agagtggatc
    46621 gagctagcta gaaatgtgaa ccaagtgatt tatgatttaa gaaaaaatgg cggcatcaaa
    46681 ttcgatgcag ataatgagga agatttttaa tgaacgaatt tgtacaagta tttcccgaaa
    46741 attggcagaa aaaatatgag gataaagggt ttatctcacc ttctcttatt caacgagcag
    46801 tttttcagcc actaagtaat aaacaaagta tagtagcggt ttctcctaca ggttcaggta
    46861 aaacactggc ttatctttgg cctctactac taaacgtgga accaggtgaa gcaagtgcgt
    46921 tggtcatttt tgcttcttct caagaactag ctattcaagt agcagatgtt gcacgtgaat
    46981 ggggaaaaga caaagagttg aaagtccaat ctttggtggg cggagccaac gtcaaacgtc
    47041 agattgaggg tttgaaggaa aaaccagaaa tcttgattgg tacaccagga agaatattgg
    47101 aattgatgaa agcaaaaaaa ataaaagcac atcaagtgaa aacaatggta tttgatgaag
    47161 cagaccagct atttgacgct gggaacagcc aaatcattga tcaaattctt catcaagctc
    47221 caacagagta tcagctagct tttttttcag cgacagcaga tcgttccctt gaaagcattg
    47281 aaaaaatcac tgggaaaacg tttgagacaa ttgacgtgac agcagaggac gattctcgaa
    47341 aaggactgag acattacttt ttacgtgtac cgatacgaaa gaaagatgac tacttgagac
    47401 gtctcacgca tatagaagat tttcatggtc tgattttctt taatcaactg actgaattag
    47461 gcgtaatgga agaaaaattg ctgtatagag gtgtaccggt aggaagtctg gcctctgatc
    47521 agaacaagct actccgaaaa gcagcgctag aacaattcaa aaagaaaatg gtcagagcac
    47581 ttttgaccac agatgtggcg gctagaggtt tagatattac aggtcttcct tatgtagtga
    47641 atgcagaagt tccgttaagt gaagaagctt atttgcatcg ttcgggaaga actggtcgaa
    47701 tgggtaatga aggaatagta attacactcg tacaagataa taatctaaga gatttaaaac
    47761 ggcttttacg tccatcaaat ataacacttg aagagatttt tttatacgga ggtaagctgc
    47821 aaactgagca gccaaccaaa gaagatgcag ctcctgcagt aaataaaaag tatgcgaaaa
    47881 ctttttctgg aaaggagcag aacccagaat ataacaaaga aaaaataaga aaaaaagtta
    47941 aaaataaatc aaaaaaagag agaaataaag gagcaaggcg caaataagcg cctttttatg
    48001 ctatgattat gaaaacggga acaaaattgg ttgccagagg aggggttatg tgaaagaacg
    48061 tcaagaagag atcttgcagc tattgacaga aaaccaacaa ggattgacag caagtgatgt
    48121 agctgagcgc ttaactatcg atcgaagcaa tgcaagccga tatttaagtg aactatacaa
    48181 ggcccatcat attgtaaaaa ccgctggccg accagtcgtt tactctttgc caacggaaaa
    48241 gtcaaaatct gatgaagtgc atgtcgactc ttctacgcaa gtgacttttg aaacactcgt
    48301 tggagaaaat gattctttaa aagtcagcat acagcaggca aaagctgcga ttctttatcc
    48361 accgcggggg ttgcatacga ttatttttgg agaaactggt acagggaagt cgatgtttgc
    48421 tgaatgtatg tatcattttg caatcgattc agagatgctt tctgcagatg cgccatttgt
    48481 ttctttcaat tgtgcggatt atgctcaaaa tccgcaactg ctctttggac acatctttgg
    48541 gatcaaaaaa ggggcttaca caggagcagc tcaagatagt cccggtctaa tagccaaagc
    48601 agacggcggt atattgtttt tagatgagat ccaccgttta ccgccggaag ggcaggaaat
    48661 gctgtttact ttcattgata aaggtattta ccgtccgctt ggagaaagtg cacaagtaca
    48721 tgaagcatct gttcagatca ttggggcgac gactgaatct tcagaaagtt tcttatctac
    48781 gttcaatcga cggattccta tggcaatcac cttgccgaat cttgcttcac gttcactgga
    48841 tgagcgttat gaaatcatct ctctttttat caaacaagaa gcgaatcgtt tgaatcaacg
    48901 tatcgatatc gaaaaagaag cgattcttgc cttcatgctt tatgatgcgg aaggaaatat
    48961 cggtcaagtg aaacgagact tgaaactagt ctgtgcaaaa tcttttttac attaccgtac
    49021 tcatcatgag aaaaagctaa tcattcgaaa agaagaactt tcccttcaag tacaaaaagg
    49081 attactgaaa atcaaggaaa taccggaacg tctcgaccga ttcatggaca gcaaaagtca
    49141 gtatttgaca tttgaaccag gatttgctga tgttgtctgg tcacaagatc cagaacgaaa
    49201 catgcaggtc tataacgata ttgaggaaaa agtcacttct ctttccgaaa ccggtgtgga
    49261 gaacattgat ctagagaccc tcatttcaaa agatgtggat gcttatttcc agacatatgt
    49321 caaagaattg actaaaagtt cgattcccaa agatcttttg ccagatgaaa tctggcggtt
    49381 aaccaatcaa ttgtatgatg tggctgaaaa acggttagac cgtatttata atgaaaaagc
    49441 tcgttttgct tttgctttgc atctgcaaag tacattggat cgtgtgagag aaggtcatat
    49501 gatcgtccac ccagatttga ataacgtacg gaaaaatttt aagagggaat tccaggtagc
    49561 aatcgatctt tcaacgatca ttgaagaaga agaacaagtt gagattcctt ttgatgaaat
    49621 cggctttatt agtatgtttc tttctatcaa tctaggagaa agtgagcctg ttaaagaaaa
    49681 caaagtagat gttctcatat tgatgcacgg cagacagact gcttcaagca tgttggagat
    49741 ggcacaagaa ctattaggaa caaaagtagg gaaagctttt aatatgccac tggttatgga
    49801 agttcaaaca atgtatgaag aagtgttaca atatgtcaaa aactatcaag agcatttgac
    49861 gaatggccta ctcttgttaa cagatatggg atcattaaac accttcagtg atttgattta
    49921 tgaagagact ggcattcgga cgaaagctat cacgatgaca agtaccatga ttgtgataga
    49981 agcgatacgg atggcaagtg ttggaagaag cttagaagat atttatcaaa atatccagct
    50041 ttcctttgaa tcgatcgtac gtgatcagtt caaagcggaa aagtctgaaa ctttacagcg
    50101 taaaaaagcc gtaatcgtga catgctttac tggtgaagga gtagctgcca aattatatca
    50161 gcgtattatg ccagtgatta atcaaaataa ggtagaactg atccagatgc agtttttaga
    50221 acgtgaatca ttcaaaaaac acatcgatgc cttattggaa gaatatgaga tcaaagcaat
    50281 tgcgggaaca gttgatgttg attatcaaaa tatcccattt ttttcagcct atgacgtttt
    50341 tgatgatgaa aaactaaata ttttaaagcg tatagctgat gatgagatcc cgacagctaa
    50401 aattgtcgat tcacttgctg gatcattaag cgatgtcttt tctattgatg aactgatccg
    50461 ttcattgcaa aagacagttc agcagatcca gaccgatttg tcgattatcg tggaacctgg
    50521 agtagatact ggaatcgtta tccatttagc cttcatgtta gacggattga tcaaacaaga
    50581 aagccatcgg caatttgaga aactgtctat tttctcaaaa atttatcgtt tggaaatgga
    50641 tatcgttcgg gcaaacttga tggcactaga acgaaaatat caggtaaaaa ttccagaaga
    50701 tgatatcgca tttcttacac aaatgtttct tgaaaataaa ataaaaaaat gaacacacta
    50761 atcatactgt ttacacacta aacatctgtg tgcgcactat aaaaaagagc taaaaagcat
    50821 gaaaacgcta tttcagctct tttttttatt ggcatgcttc ttgcgttata taaaagtgta
    50881 aaaaaataaa aggagtgtta aaaatggcaa aaaaaacaat catgttagtt tgttcagcag
    50941 ggatgagtac gagtttattg gtcacaaaaa tgcaaaaagc agcagaagaa aaagggatgg
    51001 aagccgatat ttttgcggtc tctgcctcag atgcagataa taatttagaa tctaagaatg
    51061 tcgatgtatt attattaggt cctcaagtac gtttcatgaa agctcaattt gaacaaaaac
    51121 ttgcgcctaa aggtattcca ttagatgtca tcaatatgca agactatggc atgatgaacg
    51181 gagaaaaagt tcttgcacaa gcagaaaatc taatgaaata aatcaagtat gcagttgggg
    51241 gtataacaac gtggaagatc aacaaaatct agaagccatc atggggttaa tcatgtttgg
    51301 cggtaatgca aagagcgatg caatggaagc gattgcggct gctaaaatcg gtgattttga
    51361 gttagcggat aggaaaatcg ctgatgcaga agaatcactt atacaagcgc atcatgcaca
    51421 aacagacatg ttgacacaag aagcacaagg aaatcatatg caagtgacat tattgactgt
    51481 tcacagtcaa gatcacttaa tgacatctat tgcgtttact gatttagcaa aagaaatcat
    51541 cgaactttat cgtcgcgtat acagcgaata aatacaactt cttttttgaa cggaagaaga
    51601 aaaatttttg aacggatttt ttattttgtt ataaggagaa ctctctttat ataaaaaact
    51661 tataggagga agtaaaaaat gaacggacta tcaagttgga tggagaaata catcctgccg
    51721 gttgccgcaa aaatcggagc gcaaaaacat ttagttgctt tgcgtgatgc ttttatcggc
    51781 atactgcccg caacaatggc gggatcagtc gctgtaatga tcaatgcaat tattcgtgat
    51841 ttaccgcaac agtttaacag tacctatgct gacagtttag cagcagacaa aggaatcttt
    51901 gccgtattga atgtcatcat cggaatcaat ggttttgtct ggaacggtac actagcaatc
    51961 gccggattga tctttgcctt ttcttggggg tataatcttg cccgagctta tggagtaaat
    52021 gatctagctg gggggatcgt tggtttagct accttgattc aaggtatttc ctttggtcca
    52081 gcattatcag cagcattaga tgtgaatgtt ccttcaaatg tcgcagatgc aatcaatagt
    52141 tctgagattg gtgcaacgat tgcagatggc acactgtcag ttggattatg gggttggcta
    52201 aaactagatc atttgaatgg aaacgcttat tttacagtta tgatcatggg agctatttca
    52261 gtcattattt tttgtaaatt gatgcttgcc aacattacga tcaaaatgcc tgattcagta
    52321 ccaccagcag tatctaaagc atttgcagcc attttaccag cgacgatcgc tttatacgtc
    52381 attgctatta tcaattatat cgtaggtcgt gtagctgatg ggcaactgat cattgatttg
    52441 gtgcaaaaat atattgcaga accattccta ggattatctc aagggttggg agcagtattg
    52501 atcgtcacag tatttgttca agtattctgg ttctttggta ttcatggatc aaatgtattg
    52561 gcaccagtgc tagagggaat ctggggacaa gcacaactaa tcaatattga tattttccaa
    52621 aaaggttata acggaaaaac tggtacacca gccgtgttag atgcaatcga agatggaaaa
    52681 gcttatatgt gggtccgcgg atcgttcgat gcttttgcat ggtttggcgg atcaggcgga
    52741 acgatcgtct tactgatagc tatcttgatt ttctctaaac gtgcagatta tctaacagta
    52801 gctaaattat ccattgggcc tggtatcttc aatatcaacg aaccagtgat gtttggtctg
    52861 ccaatcgtat tgaatgcaat catgtttatc ccattcttga ttgctccagt agtagcaaca
    52921 gcaattggat ggacagctac ttatcttggc ctagtcgctc cggtatcgca gcaagtcaca
    52981 tgggtagtac cgccgttctt attgtcattc ttagcaacag gagcggattg gcgggcaccg
    53041 atcgtaacat tagtatgtat ggtcgtgact ttcttgattt gggcaccatt tgtcatctct
    53101 gcaaacaaaa tggaccctgc cgcaggcgaa caacaataag atgaacgtga ggagcgggac
    53161 gctttaagtt tcgttcctca taatgaattt tcgaggagga actgaaatga ttacaattgc
    53221 cagtgcaatg caacaagatg aaatcaaaga attgttagaa ggatacaatg aagaaggaat
    53281 gacttttaca tttaaagaaa aacaaggaat caagctgttc tttgaaacaa gtgcagaaga
    53341 tccggaagtt gcggctaaaa aagcaaagga actaatcaaa gcacagcctt ggggaacagt
    53401 cctttatttt caatcaacag ctgtttagaa aatggtttaa aaagatagga tggttgagat
    53461 gataaaaaac ggtttatttt tatgtagtat tggttctttg atcgtgttgt atagtttgaa
    53521 tccacattcg caaaggtatg atttgtatag tatggtcaca ggtctttttc taacaggatt
    53581 aggaatctat ttcttcatga aggggaaaaa aagagaagaa gcaaaggaga aaaataacta
    53641 atggaaatca cgaaaaaatt aaatattcca gcatcgtttt tttacgataa agttatggac
    53701 tctgtccttt tcgatgtacg taaagcgacc ggcaaatcag taactagaaa acagctgaaa
    53761 aatttggagt acgtcaaaca attctcgcaa aataaccggg ctcgcataaa aatcgaagaa
    53821 gtcattgaaa accagtctta taagtttcgt acatcgacaa cgaagaatga attcgtcgtt
    53881 cattatcaaa tcaaaccatt ggacgattcg acctgtgagg ttcattacac agaaaaaatg
    53941 gagtcttatg gcatgcttca aaagttgaat gatatgcttt taggaacaat cttgatgtat
    54001 tttaaacgga gacgtttcaa aaaaatgcta gatatgatcg aagcaacgta ttaaatcaat
    54061 gaaacatggt actatttagt tattgaaaaa tgaagtaagc tagaaggaat ttttcatagg
    54121 aagatagatc tttcctgcga atcctcacta gcttttttgt aggaaggggc agcaaaatga
    54181 caaacaaagt aagagagcta ggtgtatctt cgattgagga aatgtttgat ttagccactt
    54241 atgcatttaa tggggcagat acacctgaaa ggcgagaacg ttttcgtaca cttgcggaga
    54301 attcttggaa ttacggattt tttgatgagg aggatcggct aacaagtcaa gtcatggcga
    54361 ccccttttcc agtgaatttt tacggacaag agtacctaat ggccggcatt ggctatgttg
    54421 cttcttatcc agaagcaagg ggacaaggcg ggatcaatca gatcatggaa aagatccttg
    54481 aagattgccg tgatcgtaaa gtaagcttat cttatctggc gccattctcc tatcccttct
    54541 atcggcgcta tggctatgaa caatcatttg ataaaatcag ttatcaacta aacagtcgtg
    54601 atgtgccgtt tatcaaaaaa aaatctggaa aaataaagcg tatggatttt gaagatgcaa
    54661 aagctgcaat cagaagaatt tatgaacaga tgccggaaaa ccaacgagct ggtctgaagc
    54721 gcgaagactg gtggtatacg tataaattca agcaaaaagg caattaccag tttgctttgc
    54781 attttgatga taatgaggaa gcaacgggat atatcgttta tcagcttgca acgtcttcct
    54841 ttattattgc ggagtgggga tttttggatc atgatgcttt ttgcagcctt gttcgcttcg
    54901 taagttctca caatggtgct tttgaaacat ttgaatattc atgcggctac ggcggtaatg
    54961 atcaaaatta tctattagaa aatccatttg cttctgtaat gatcacacct tatatgatgg
    55021 cgaggatcgt agatatttct ttgtttttgg aaaattatcc atttaaaaag agacaagctg
    55081 catttgccct acaaatagaa gaagatcatt atgcgaaatg gaatgaagga atcgtggaag
    55141 taacaatcga aaatggaaaa aatcatctct caaaagtaga acaaacaaaa ctcccaatcg
    55201 ttcgaggaag tatccaacat atcacgcagc tattattagg gtatcgtaaa gtggaagagt
    55261 tggtattcca agaaagaata caggtgacaa aagaatatga agaaacgtta agctcaatct
    55321 tgccacagca acagccaatt cttaatgact atttttgata aaaaacgggt gatgacaata
    55381 tttttgtcac cacccttttg tttttcattt ggcatttgaa ggaaaatgtt aaagtaaatc
    55441 ctcttttttc gtaaatttga attttttgtt ttcttttgtt ttagggtttt cttttttgtg
    55501 gtcttggatt gcttctttcg taatcttttc ccgatttttt ttagatgaat ctaagcgttc
    55561 tgcgtatact ttttcttttg gcttatcatt cattggaaag gacctcccta cattatttca
    55621 ttctacctct agtttatcat ctgttaagga ctagtggaaa cgttttgcct aacttataag
    55681 ctgatttttt tagcagataa gcttgcaagt aaaaaacaaa caagctacaa ttgatttatt
    55741 gaaattgttc ctgtagctca gtaggataga gcaatcgcct cctaagcgat aggtcgctgg
    55801 ttcaattcca gtcaggaacg tataaataac ccctgtatcc tttgcggtac aggggtttgt
    55861 tttgtatttg tgccaaaaat gtgccaaact agttatcatt tttatataaa ctatcgaaca
    55921 cagtattgat tttttcttta tcctgatctt caagctctcg aacaatatga agataagtag
    55981 acattgtagt ttctaaactg ctatgtccta aacgtttcga tacgctaagt atatttactc
    56041 cttgataaag taaaatagat gcatgtgtat gccttagtcc atgcaaagta aattgctttt
    56101 caatccctaa ttcttttaat tttttgcgca aatatttgct gacggcgttt gatgaaacta
    56161 atccattttt taagttgaaa aaaacaaaat tatgagggtt tttgatttca aaattctcga
    56221 ataattcttt ttgattgatt ttaaactttt ttaagagatc aatcgtatgt ttatcaatgg
    56281 aaattttcct atttgaagtt tcgttttttg tttttcccca ttcatttaat ttataattcc
    56341 atgttttatt aatagtgatg atttgatctt cgaaatcgat atcttcccat gttaatccta
    56401 gaagttcagc aaatcgcatt ccagtggcac cagcaactaa cacgagcata ggagaagagt
    56461 actgcgcaga aaggttttct tctacgagtt tcattaaaga tttaaattga tcataatcta
    56521 aatatttatc ttcttttggc ttcaatgaat cttttccttt gattactgct tttctagttg
    56581 gatcaaacgg aattaatcct tcttctacgg catctttcaa cgacgctcta atatggttat
    56641 taaacttaat aacggtagat tttacatggt ctttagcata cttatttaaa aagcgttgat
    56701 atcccactct atctaaatca gaaatcaata ccgctggcat atatttcttt atgttcatta
    56761 acgtatcttc gtattttcta taagtgatag gagatactgt tccttcttta taaagttgca
    56821 tccaatcctc aaagtaatct gataataata gatttttgcg atccccttta aggcctttgt
    56881 tcaagttata ttctaattcg ttggcggcat cttttgcttc gccttttgtc ttaaatcctg
    56941 attttcttat cttcgtgtat tttccgtcat cttttttgta tgaaatttcg tattgccaac
    57001 tatttccacg tttgactaat cttgccataa ttgaatctac tctctttctc tgatacaata
    57061 ggcactataa agaagcctac tgtataggtt tgtttttctt agaacacgct tgctttggac
    57121 ggtgggcgtg ttttttattt attatacagt tgctttaaaa atagctgctt tttcaaatga
    57181 tactaaagga gagaagtgga tttctatttc tcccttttgg tttaacgtga aatgagcagt
    57241 tacatccatt tgttttcctg gagcaacaga tcccattgta ttttcgttgg catatgtctc
    57301 tgattttttg tcatctggtc catatacttc cacatctgta cctacaggga tatctgaatc
    57361 gccatcattt tttacggtat aagtaatttt tactacttgt gcaggttggt tttcttcaaa
    57421 ttgatttctt tcatcagtta gttctacact atttagtgta tattcagcat caccaacttt
    57481 tacagtgtca ccaatcttat agaaggtatc gcttttttct tctttagaag atgaagcaga
    57541 ggttgaagat ttagttactt tttcgccacc attatcactt gctttattac tatctgatcc
    57601 accatttaaa gcagaaccaa taattataat taaaattact gctaataccc aaaaccatac
    57661 ttttttgtaa aaaggtttac taactttata catttttccg tcttgaccca taactttttt
    57721 tgccatttaa atattcctca cttcttgtta taatatattt gcgatctcag aaatgaggta
    57781 tgagtccgtg tgccagcacg ggctttttta atgttttgct gaaatcggtt tttttaataa
    57841 ttcttgatgt attcatacat attgccttgc gtaagaatat tttttcttaa aatagcattg
    57901 gcagacagca taacaagtgt atctgagctt attctgaata gaataatact ccataaattt
    57961 ttcgagatta aactgagatt catcagtcag ttcgttctca atatagatat ttaataaaat
    58021 tagaatagct attttatctg cttctgtttc aaattttgag tgaaaagttg tagaagtatc
    58081 gtacaaaact gaatattcaa aatgagaagc ggtgaaatgc gcaagttcat gagataaatg
    58141 aaaggcttct gcagtttcgc catatagatt ttcattcaaa aaaatgattc taggcttcgg
    58201 ataatagaag ccaggctctt tcatttccat gtaaactact ttcaaattgt attcgctcaa
    58261 catttctttc aatttcaaat acatacaacc catcactcca actattcatt ttcctctaaa
    58321 gctttagcaa ttgcaatcgc tttacgcatt gtctccttag atatttcttt tccatcaaaa
    58381 gaaaaaacag tatcgttttc tgataaatcc acatgtttag gggtttcttt ttcttcgcgc
    58441 cccagaagat agtctacaga gacatcgaaa tagtcagcaa tttcttgcaa acgttctgta
    58501 gaggggtttg agttcttaag tctatataag acgtttttac catagcctag gtcttcttca
    58561 actttattta atgattttcc ctgttttttc gctaactctt ttattctctc aaacgttatc
    58621 atatcaatat tcctttcgtt caagaaaaaa tatttaactt tatttgttaa aattcgttga
    58681 ctattttaac aaaaggtgtt aatatcattc ttgtaaacaa gtttaacaac taaaaagaca
    58741 acaaaaaaca ctatcgatta ataaatgcca accgccaaga aagcttttaa aatcaatgtt
    58801 tatatgtctt atttaactat gttctgattt taacactgta tgttaattta gtcaacgcag
    58861 tttttttaaa agttgttaaa tttgtttacg aatataaaag aaaggagaga agaatatgga
    58921 aaaaacagtc tcggcaaaaa tcgaagattt gaaattagac atactgaaac aagcaaaagt
    58981 ggcgatggaa cacgcggtag ataaagaaga ctctgccatg gttgcagcca tagcagagat
    59041 tttagctcac gtttagtcat cgtttttacg gtcttctgga agctgaccat agataacagc
    59101 ataatgaata tctaaataag cttgagcaat ttcttttggc gaaattgatt cgcctttagt
    59161 agatacttgt gattcgtgat ttagccatgc aacaactaaa tccgcagcga tttcatcagt
    59221 ttttttattc atacttattc accaccttat gcattatttc agtagaccac ttactgataa
    59281 gaaaattata tcaaagaaag gaatgaacaa aaatgaacac accacaaatt tttagttttg
    59341 aacaacatga agtaagaacg tttctagaaa atgacattcc gtatttcgta gcaaacgatg
    59401 ttgccaaaac tttgggatac aaaaatccca gtaaagccac caatgatcat tgtaaaaaat
    59461 caattgaaac atggggtaac gattcgttag gtcgtcgtca aaaattcaaa gttattccag
    59521 aatcagatgt ttaccgcttg attattaaat cgaacttacc aagcgctgaa aaatttgagg
    59581 cctgggtaat ggaagaagtc cttccaacaa tcagaaaaac aggtagctat tcaaacgtac
    59641 ctcaaagttt tgcacaagca ttgcgtttag cagcagattt agaagaaaag aaccaattac
    59701 tcgaacaaca aattgccgag tacgaaccaa agattagcta cttagatacg attctttcat
    59761 cgacagatac ggtagctact tctcaaattg cagctgatta cggaatgtcg gcaattgctc
    59821 taaacaaatt gctaaacgag ttaggtgttc aacataaagt tagcggacaa tggatacttt
    59881 accgaaaaca tatgaaccaa ggatacacaa aatcgcacac aagtgagatt ccgaaagccg
    59941 atggcggcac taaagttgta atgaatacca aatggacaca gaaagggcga gtgtttattt
    60001 acaacttatt aatcgcagag ggctattacc ctcaaatgga tttagaggaa attggttaga
    60061 aaggagtttt agtatgactg acattgcaga aatcactcaa cgagatagag aaaaaatcaa
    60121 agaatatgtc gaaagttcga agttcttaac ttacaccatg cttgctgaaa gatttggaat
    60181 tagcaaaagc tacttatctt taattttaaa cggtaaaaag acttctgcag aagcaaatag
    60241 aatcatagat tcgattatta ctatgtacga attgtaaagg gaggaacagc taatgcaata
    60301 tctagaagcg aaaatcccag ttccagaagg ctatgtaatt atctcccaag tggattatga
    60361 ggagttaaaa aaagctgatg atactggtag atggatgacg ttgccagaag tgctagaacg
    60421 gattaacaga aaatatgatt ggtttacttc tagagtttta aagaacccaa gatatagaaa
    60481 tattatcgat atcgagaaaa acaaaaatgg atttgtctat tatccagttg aaggaagaga
    60541 cacatatcta tttttaagaa gtaaaacact tgaattttta gaaacaaatt tttcggaaat
    60601 cttaaggagg caagcggatg ggaaaattta atagagcgct agtgttcagc gcaccgctaa
    60661 tcatctacgc tttaggactt tggggaagca ggcaagcgtt gataggaacg attgtttaca
    60721 tggtttggat ttttatgggg cttgatgaag ctgaagctga gtacagagcg aaaaagccaa
    60781 ccgagggggc tgactaaaaa tgaatagaaa agagaaacta gaatgtatat tactattact
    60841 cagtttaatt ctttcactaa tttctctatt gggaagtttg tatttttgat atcaacaatt
    60901 ttgtggattt gggttctatt tagagtaaat atcatttttg tttggtgatt aaggagttta
    60961 ttaaaattaa ttttccctac ttcaaatgca aggtaacaag atatagcact tttaggagga
    61021 atatttagcg gtacagcttc agagtatatt ctattatcat cgactgatcc tcctttagca
    61081 attaatttct taaatggagt agctgaccat ctgcggttta agttagcgga tgaaagttct
    61141 aaattaacta acatagctgg ttctgttgaa tagttagaaa tgattacttt tgtataaatc
    61201 atatctgcag cgaagtaaga agcattaagt tcaacttcta gttgagggcg cattcctttt
    61261 atttttatcc ctgttaaaaa cgtactcaat ataaaactta ttattgacat ccattgaaaa
    61321 attgttaagt gaaaaaaatt caaaataaac accaccagtt tttaactaaa ttataccaaa
    61381 aaggagagaa gaaataatgc aagaattagt aattttgaaa aataaagaag ctgtgactac
    61441 gagcttacaa gtggcagaaa gcttcgagaa aaaacatcaa catgttttaa gagatattga
    61501 tgcactaaaa aaagatgtgt ccaattttgg acagatgttt gtagaaggta atgaaccaga
    61561 ttcatatggc agaaatcgac gagttttctt cattagtaga gatggatttt tcttgctggc
    61621 tatggggttt acaggaaaga aagctatcta cttcaaacaa aaatacattg aagcattcaa
    61681 cgaaatggaa gatgttattc gcaagaatac tgttcctcaa acaattgaag atatgatgat
    61741 ctatcaatta gaagaaatga aagatgttaa aaaagatgtt tccatgctta aagatactat
    61801 gcgaattagc ggacaacaag agtttgaaat taagcaaaaa ggaaatatga aagttatggg
    61861 agttctaggg ggaaaagaaa gccgagctta tgaagaaatc agcaaaaaag tattctcaaa
    61921 attttggtct gaatttaaac gtaccttttc aatcccaaga tatggcgagt tacctcgtaa
    61981 gagattcgat gatgctgttt catttattga aatgtggttg ccagaaactg cgatccgtat
    62041 ggaaattgat caactgaaca gacaacagag actttttggt gatgacaatg aatagagctg
    62101 aagcgctaag aatagggacg gcaattgcta attgctggtg gaaatactat aaaccaatca
    62161 tcctaagcca acaacatatt gacaagcaaa aagcatggca acaaataaaa aagtgactcc
    62221 gccggcaagc aaagagtcac aaagaaaaca catcataagg agattttagc atatggaaaa
    62281 agaactttcc actctagatc aatatttgat tgatcctgat tggggcaagc cgaaaattga
    62341 ggaaacaagt ggtcgaaaaa tcagacgaaa tcttttgacg aatgaagaac tagcttggga
    62401 tcaagatgat ttaggcaacc atgtaactat ttgggatcat gtttatctta tccatctatc
    62461 gaagcattcg aataaacctg aatatattta cgtcatcgaa gatggcttga ttgatgcgct
    62521 agaagagtac gacagagata acttgattga tatctcttat tacggaccag gtaagaaata
    62581 cattgctgaa atggaggcag aatttgatga gtgaaatcaa agggacaacg aactttgaaa
    62641 aactttttag tcgtaagtta aataaaattc tcaagaaaaa aggaaatttt gattatttat
    62701 cttgggctca cgcgtgggag attatgaaaa agaatgatcc acaggcaacg gtaactatta
    62761 atgagtacaa acactacagg gttgtttctg gaactcatca agactttctt gttgaggaat
    62821 ataaaccttt tcttatggat gaaactggga cttatgtatc tgtctcagta acggttaaag
    62881 gacacacgga aaccgaatta tttcctgttt tagattatcg aaaccaacca gttgttaaac
    62941 caaatgcaat gcaaatcaat aactcattga agcgatgctt tgtgaaagca ttggctctac
    63001 acggactggg attatatgta tttcaagggg aagatattcc aacaccacct agaatcgata
    63061 caaagaaatt aaacatgcta gagacgattc tagaagcttt caatgagcag atgggtaaag
    63121 atatgaccaa aaccttaatc gaatatgtta atgagcagac agataaatta gggctcttag
    63181 ctgataacgt tgaaactatt gaacagttaa gctatgagca atgtgccttg atggagcgag
    63241 caatagcagc taagagaaaa gaattagata agaagtgata tgagtgttta aaccattaat
    63301 cgattcatat tcagcggttc tgaaaaagtt caaaggaaaa gacataagcg caaccatcaa
    63361 tgaggaagtg aacattgatc gactaaagac gatgtatgac ggctacgatg gtgatcgagt
    63421 cattgaaatt cgttttattg atcctagacg tttcaccgta cagcaacgaa acttcatcta
    63481 tgcgctgata ggcgatattt ttatcgatac aggcatgcca acggacttct ggaaggaatt
    63541 cttctacttt cgttttgaag gtgtcacagg gcgcaaaata agcctgaaag acgaatcgaa
    63601 tacaactgtg agtgatgcca atgtcttagc aaatatcatc ttagatttca tctttgaaca
    63661 tcatattcct ttcaaagaag gctatgagat tttacctgcg aatcaagaat attacttcta
    63721 caaatgcatc acaaaaagag tctgctgcat ctgtggcaaa acaggagctg acatcgatca
    63781 ctttgacaaa gcgctaggaa gacgaaagcg caaagaagtt gatcattcag agtacacatt
    63841 tgcagcactc tgcagaatcc atcacacaga gaaacacaaa ataggtgtga tcaatttcaa
    63901 aaataaatat caaatcaaag ggatcaagtt aaaccaggaa acaattaaaa agttaaggat
    63961 aggaggataa atttggctga gataagttgg atcaaactta aaactactat gtttgacgat
    64021 gaaaaaatac gattaatcca agctgttcct gagtcggatg ccatcatcgt tatatggatt
    64081 cgattactag ttttagcagg aaagactaac gacgatggtc tgatatatat ccagaggaac
    64141 atgccttata ccgaagaaat gcttgctaca ttgtttggca aaaacgtaaa tacggttcgc
    64201 ttagcgctaa ctacattggc aaatttcaac atgattgatc taagcagtga tggactaatt
    64261 gccatcagta attgggaaaa acatcaaaat atcgagggta tggataaagt aaggctaaaa
    64321 aatgctgaaa gaaaccgtaa atacagggaa agaaagagac aggaacgtct caaattggaa
    64381 aatgacgtta gcgtgacgtc acgtgacggt acagataaag atatagaaga agataaagat
    64441 atagataaag aagaaaagaa aggtaagtat tctgacgaac acttacgcct tgctaaaaag
    64501 ttgcaaagta atttaactga agattttcca aaagaaatga acaaagtaga tatcgaaaaa
    64561 tgggcagaca caatcaggtt gatggaagaa agagataaag catctataga agcgattgag
    64621 tatgtgatca attggctacc tacaaatgaa ttttggtttg gaaatattag aagtgctaag
    64681 aaattgagag aaaaatttga gaagctcaaa ttcgaaatca aagcagacaa gaagaatcat
    64741 aaaaagcaaa gtcaaaaact acagtacagc aatcctagtg aatatgacga cttgccaatt
    64801 taaaaaggag atgcatcaca tggaaagcct agcaaatgct atggagaaac taataagaag
    64861 agtattagtg caaagcggaa aatgtccaga atgtagcgaa cctttgtata gttggcgagc
    64921 taaaaataag gatggttcag aacgttgtaa accaacatgc atgagttgtg gttataaagc
    64981 gttacgtgtg aaagaggata tacagaccga acggatatat aacgatagct taaaagcacg
    65041 agcgttgagt ttttttcaaa atggttcggt attaacagat aaaactttgt ttaaatgcaa
    65101 aatggaaaat tatcacgtag tggatcaaga aacaaaaatc gctttagaaa aagcaaaaag
    65161 ctatacgaat gaggttctgc tgaaccatcc tgcacatttc attctatcag ggaaatcagg
    65221 aagcggaaaa agccacttat caatggccac agcttgggaa atacttgagc gctcaaatta
    65281 tgacaagaaa atacttttta taagctatca agaattatta gagcaaataa agttttctta
    65341 taacaatact gaactgagaa aagaaattga aggatcgctt atagccgata ttaaaacaac
    65401 tgatttggtg gtttttgacg atattggagc tgaattaggt agtggggtat caaatagtag
    65461 gcagtttaca aacaacacgt taaacacgct cttagaagcc agacagaaca aggcaacgat
    65521 tatcacaaca aacttatctg gtcccgaact aagagaagcc tacggcgaaa gaattgtttc
    65581 taggatattt aagaattcag aaggttatgc gctgaaattc caacaaacag cagacaagcg
    65641 cataaaacca gtgaaaggta gtatcgcatg aataaatacc gtaataagaa aactgttcat
    65701 cgaggtatca agttcgattc tatcgcggaa gcagagtact acgatctagc cttgtggcaa
    65761 gcggaagcga atgactggaa agtaaagctt caagaaagat ttgagctgat gccgaaattt
    65821 gaactcgaag gcaaaaagta tcgcaaaatc gagtatattc ccgacttcac attttataaa
    65881 aatggcaaac ttgtaaaagt cgtagatgtc aaaggaatgc agacaaaaga ctttaagatc
    65941 aaggcgaaat tgttttgtca tcaatatcaa gttccattga tattagctaa aaaatatcgg
    66001 aatacgttca aggaagagcg tttttaaaga ggtggtccat catgacaaca gaagaagtga
    66061 ttcaaatgcg tattcgaagc attcaacgtg aaattgacga tctggaacga acaaaggcag
    66121 tgatggtcaa tgaaacggct agaaaggcaa ttgatttgca catagagaac ttaagaaggg
    66181 aaattcgtag attggaggaa tgagcgtgga taagaaagca gcaatgaaac gaatcatcga
    66241 actgacacat tctgagaatt ggcaagaaga caaagaaata gttgcagaag tccaaaagct
    66301 cggtaaatca atgtggactg aaaaaaccag acggagaatg ccgagaaaaa ttgcaatctg
    66361 gcacggtgac cgaattctag taacaggtac cgctgaacag ttatctgaaa ttactggtct
    66421 gagcaaaaac atcatctggg atagagctag gagcttatgg attgattcaa aaggacgaca
    66481 gtttaggtat gtggaggaga aataatggat ctcattacac aatatagtga tatcatcctc
    66541 aagaaaatca tgatgaagat tcagaaagac aaaaaatcaa aagaacgagc ggaattagtt
    66601 aagttggaaa tggctgaaac aggagcagga gtgcgaagta gcaggcattg gaaagcagca
    66661 gcaaacattg aattttatta caacgaaatt caaaaagggt tcgatcagat gcgtgagctg
    66721 gatcggcaaa caaattggag caagaaactt catcaagatc gtttcaaatt tgtagagaag
    66781 tataaagaga tattagacga atacatggag ggcagcaaat gataccgaga tttcgatcgt
    66841 ggtacacacc atttaaaggt aaaacaattg gacaagaaat gaaatatggg caagcaggaa
    66901 ggttgatcac tcatgctgaa atggctccag ataaatatgt gcttatgcaa tccacaggac
    66961 tgaaagataa gaatggcgta gaaatatttg aaggggatgt agttctggtt aatgtaagta
    67021 atggttttga tcatttagtt aatgaaaaaa cggttgtaca agaatccgag tttcattccg
    67081 gattagtttg taaatcatta attagtggaa tggaatatag aatattcagc caccaaaaga
    67141 tgggatacga atatgaagtc accggaaata tacacgagaa tagcgagtta ttggaggtag
    67201 agtgattatc ttagctactg actacatcga ttctttaaaa gatgaaaatg ggaatgtccc
    67261 agcattgcta aattgtggaa ttaaaagtaa gaatagaatc attttgttac ggatatcggc
    67321 tgatttagca aaatatcttt atctgagcaa gacagcagta tattacactg cggctacacg
    67381 ttatcagtac aagggaaaaa caatcagtca ggattattat gatcgtttaa tcagtcctga
    67441 catacatgga aaatcaaaat cagcgatcaa gttatttggc gcaatagaga tatatgccga
    67501 tgattttcca aatttatggt tgaaggagga acagtaatga aagactggtt agaagaagca
    67561 agcgccttag ttggctgttt cataaactgt gcgtttatat ctgtaattat tgcactggtg
    67621 ggatttgtat cattgaaagt gattatattg ctttggcagt taatttttta ggaggaacag
    67681 cgatgaataa acaggaagca atcaaaaagt tagaaagtat taaagtgata ggaaatgatg
    67741 cactagctgc ttgctataac gagagtataa atgcaggtat tacgttaatg aaaaaaatag
    67801 acgaaccgaa gaagctagtt attccacaac tcgtggccgg ttggcttgag aaatctacgg
    67861 acccttttac gaaagctgaa aaaatagcgt atttaatcaa atctaaagat ggtgattcat
    67921 attatttctg tgattggttt gtacgagatg gcatagtgac gcaagaacaa ggagaagaat
    67981 tactcgcttg ggcaacgaga caatcatatg aaacactatt gagcttgtac aacggctacg
    68041 aggtcgagaa agagccgttg tacagtgtaa taattgctgg cgagtacctt gtcaaggaga
    68101 tcagttgcag taatgaagtt aaactagtat caacagctta cctgccacaa taccttgcac
    68161 accactacca actgaccgaa aaacagatca aagcaattga tgaaagatac tggccatttg
    68221 ctgtgccagt ggaagaggtg gcggaaggat gagtagacag ataatgctcc atataccaga
    68281 cggaacaaag gcaatgacga ttaccattgt tgctgcacaa aaagacggtg ggttggcgtt
    68341 gaaaacaaaa agcattgata ccaaacagat tttagaaggc agagatgtcg agatagagat
    68401 cgatgaggag gaagcggaat gaatgttcaa gtttatttaa aaagagattt ggccaggttt
    68461 cctcgaagct gggatacaaa ttcccaccca tccgaggcag aagaagaggg ctatctaatg
    68521 tctgctaaca tgatagaaat tacaagagat gatgcggatg agtttgataa aaaaagatca
    68581 tggtactcgg ttccgaatcc aatgtatacg gctgtaatag aagattatca tatatccgac
    68641 agatttattc tgattgatct agaaaggcct aagaaacgaa ttaaacagta tagacgttgt
    68701 ggattttcaa caaagaaatg gtgataacaa aacagaggtg aagaaaaatg aacaacagac
    68761 accgcagagt agcaaaacta agaaatcaag aactgaatgt agcgaaagta aagttcgaac
    68821 gggagtatgg tgtttctgca gaagaaacat ataaagtggc aagtcagtgt gttgctgatg
    68881 caagtgatgc tattcgtaag tttggaattt cgatactaga tattaaatgg gaggatacag
    68941 aatgaagatt tatgtagtaa agtttggaaa tcaattttac agaagcgatg aacgttctat
    69001 aggggctaac acattatcca ttgtagacat actccaaagc gcaagatggt ttgataatct
    69061 cgaagaagct aaccaagttt cacgacgact tggtggatta acgcaagtat atgaactggt
    69121 cactgtcgat catgaggggg tagagtaatg aaactaaaag acggatttta cgctagtagt
    69181 catggtatcg gcggtttgat gctagatatg ccgacaaaga accctaaaac acgtgagaaa
    69241 ccaaaattca aagtcggtga catggttcgc tgtgaagcag aaggatttat ctatccattt
    69301 cgtggatatg tagaaaaggt attgtcgaac tcagcaatca ttcgtattga aaacacgatg
    69361 gaatgtgaca agtggttagc gaaaagcaaa gagaatttag ctgtagcgag attagttgac
    69421 atggaagtaa tcgagagcaa ataaaaaagc cggatcgctc cgactaacat aataaaacag
    69481 acaagtttat tatatcacat aaaggagagg tttgacttga tgcaattgtt acgagaggta
    69541 gatttcaaac agacaagatg taatgcgaga gatgtgctga agaactttcg gcgtttggag
    69601 cggatggcag gtcgctcttt gatagatatt aagtctccaa ttattacgga tatgccgaag
    69661 gcgccgaagc acggcaataa ggcagaggac gcgatcattc agatgatgga tatagaagca
    69721 gagagagatg cgattttagc ggctttgatg gctcttagtc tgattagccg tcagatactc
    69781 tactacagct tttgtgtgcc agatagcttc tcaaactaca gaattagccg tgaagtgggt
    69841 tattcagaaa gaagtataca acggatgaag tcggaagctc taatagagtt tgcagaagca
    69901 tataaacacg gaagaataat tgcttataaa taatttggcg gttttttggc ggaatgatgg
    69961 cggtttttag ctatttacca gtgatattat ggtagtgtcg aaagattagt gataggtctg
    70021 agacaaaata ataataaaag gaacatcgtt ttattattgt ttcacaatta agcttcgata
    70081 gacagcaacg gaaatattaa gaataaggat gtgaatttca actccttcta aattgttctt
    70141 attatctatc atccgttgct gtctattgtt tttttaatta ttcacacgat aactaaaggt
    70201 gagtgaagag aaatgattcc attaataatt tcaatttttg cgctctgtct taatgtctat
    70261 atgattggat ttaaaaatgg gcaaaataaa aaatagtagc agccaagaat aattttatag
    70321 tgtcactgtg gcggaaaggg tagacgctta aaaataaggt caatacgtcg agggatagcc
    70381 ttaacgtttt atgatttgac catgcaatgt tcgattcatt gccagtgact ttggcaaccg
    70441 agggttggaa atgggcgctc aaagtacacg agcaaggcga ggtcgatagt aatcgatgga
    70501 atcggtgtag gttgcttgat agagctataa ctgcatctcg tttatgaggt gtagttttta
    70561 cagattagat cactctttga gtggtctttt tattttacac aaaggaggta acaagaatgt
    70621 atagaccaca atacttagaa cagaagtatg aagtaatcac tgtgcaaaac ggtaacggtg
    70681 agatagtacg aaagtataga agaccaataa agagcgatac atacaaacga aaggaaagca
    70741 atgaagttat tccattgtat ggcaaaagaa tagctaagca ttaaataaga ttgcgaaagg
    70801 agacggaata tgaccgagga attctataga tggctattac agttgataag agaagatcgt
    70861 ttagttaagt tctatcagtc tcctaaatgg cgcaggctta gagagaaagc gatgaaacga
    70921 gatcactatg aatgccaaga gtgtagaaga ctaggtaagt atcatagagt agaaaacgtt
    70981 catcatataa aggaagtcaa ggatagacct gacttagctt tagatttaga taatcttatt
    71041 tgtttatgtg ttgaacatca taatgaagtt catggcagat atcttacagc attagataaa
    71101 caagagaaga agatagaaag ctttgctaac ttcgatgcaa gtgaaaggtg gtaagtgcat
    71161 gatcatcaat gataatggca gagagtatga tacagaaaag attgaagagt attcatctta
    71221 tactcaggga ttaattaaac gtttgatata cgttcgctat gtagatatta gggatctgtt
    71281 atcagataac tgttgtagta aatacaaagt gaatcaagta agagaagcgt tgaataaaga
    71341 taataacgtt gaaagaataa aaaatatttt tggatatagc attgaagaga ttaattatta
    71401 cattgacttc gctgaagctt tcattccgat ggtgagataa ccccccctta aaataaatcg
    71461 caaatttttt gggggtgatg aaacggaggg ggctgtcagg aaaagagatt ttttcgaact
    71521 ttatcatgaa aggagggcta aaatgtttaa aaacgaattg tctcaaaatc gctacagaga
    71581 aaaattacgc cgctctttaa taagccaatt ggaaagtcag aaaacaaata ttgagccatt
    71641 cttagataat gttgatcgtt atatcagttt atgggaaacg gcgatatcac tggaagaaga
    71701 tatatccgag aacggcatta gactggagaa tggtaaaaag aatgaatcag tagcgttgct
    71761 tgtttctgtc aacaaacaaa tgggattgat gttggataaa cttgccatta ctcctgaatt
    71821 ggtaggtgaa gcaaatgaat caattcctga gttataagca tattgaaaat tggttcaaag
    71881 ctatagaaga aggcactatc aaggtatgca aagagcaatt attgctaaaa aattatctag
    71941 aagaaagagt ctttactaga gaagatattt acttcgataa gcagatggta gaggattcaa
    72001 tcaatatacc agcacaatac tttccattcg aattaattcc gtgggaaaaa tttctacaat
    72061 gttttattta tggtgttcga tggaaaaaag ataaaacact agtgttcaat agatatcttt
    72121 cattaatggg acgtggtaat ggtaaaactg gttttgcttc ttggaacaac ttctttctac
    72181 taaccgctaa acacggtatt aaaaattata atattgatat ctatgccaat aatgaaagcc
    72241 aagcaaagac tagttttgat gatgtattta aagtaattaa agatcatcct gatttagata
    72301 aaaaagtatt taaagctacg aaggaagtta ttcaaaatat cgctacaaac agcaaacttc
    72361 gttataacac ggcaaatgct agaacaaaag atgggaagcg accaggtgca aaccgctttg
    72421 atgaaattca cgaaaatgaa gattattcaa tgataaatgt ggctacttct ggtggtggta
    72481 aaattcgaga ttatagagaa ttttatgata caactaatgg tcatgttcgt ggtggtccgc
    72541 ttgatgacat tatagaagaa tcaaaaatga ttctttctgg agaacttgga attgacaagg
    72601 atggagcaga attttctagt ttgtttccat ttatttgtcg cttggataac gataatgaag
    72661 ttgatgatcc cgacatgtgg gaaaaagctt gtccaactat taattacaat gcagatttaa
    72721 aacggaaaat gtttcaagaa tactctcaaa tgcaacgtaa tgctggttta agacttacgt
    72781 tcatgaccaa acgaatgaac agacctatgg aagatacacg atttgctgtt gcttcatatg
    72841 atgatgttct gcatacgaaa gaaaaagaat ttcctgaaaa aatggatgaa gtgataggaa
    72901 cagtcgattt tgctgataga cgagattttg ccagcgttgg gttgctagga aaatacgata
    72961 aagatgttta ttttacacaa catactttta tccacgaatc agcccttcga ttacaaaaca
    73021 tcaaacgaga ggttatagat atttctatag atcaaggaaa atcacagatc gttcatggaa
    73081 aaaatataga agctgattat attgtaggtt ggtttcttga aatgagtaat aaatattata
    73141 ttaaaaaaat cgctatggat atgtaccgtg caaaaatatt gaagcccgct ttagaagaag
    73201 caggttttac tgtggaaatt gttcgaagcg gatctgttac acatggtatg ttaaaagatc
    73261 tggttgatga cctttttatt aatcaacgtt tattttttgg tgacgatgcg attatgcgtt
    73321 ggtattgcat gaatgtatat gaagagcata tttctaatgg aaatatacgc tatgaaaaaa
    73381 tagaacctga aactagaaaa acggatggct ttttttcatt ccttcatggt ttgaattttt
    73441 tagatgatat ttatgattct gctcctgtaa cagtcacaaa tagctcagta gaaaatacag
    73501 gaactggatt tactcctcta gtattctaac ttgaaaggag gtgagaaagt ggggattttt
    73561 caaaaggcgg taggatactt cacaaaaaaa gcaacggttc ctttagaaga atacttttgt
    73621 aaattgcaag ttgattttgt gtatcgaaaa tttgcgattg aaacttgtat tgatttgatt
    73681 gcaaatgcga tgagtaaagc ggaattcaag tcatatgaag atggaaaaaa taaaaagaat
    73741 gatctttact ataggctgaa tgtagctcct aataagaaaa ataatgcaac agaatttaga
    73801 aaaaaactga tcaggagatt aatattctac aatgaagtat tgatcgtttc tccgtctaat
    73861 aattctagcg aaatatttat tgcggatagt tgggatgtca cagaatatgc attgaaagat
    73921 gatgtgtttt ctcaagtgca aattaacaac atagtccttg atagagaatt tctagaaagt
    73981 gatgttatct atataaaata cgcagatcaa caaattaggc aactagtcga tgcgtattat
    74041 caagcgtatg ggaaactcat ttctagtgcc atgaatgttt acaagcgctc taacgctcgt
    74101 agatacgtac tgaaagggaa tttattccga ccgcaagaca atacaacaca agatcaaatc
    74161 aataaaatga tgacatcaca atttaaggct tttatggaag ctgataatgc aggtgcggta
    74221 tttcaattac aaaatgagta cacattagaa gatttcagcg gaaacttcca aagcaattca
    74281 agagatataa aaaacttaat agacgacatc tttgagatga cagcagcagc gtttcacgtt
    74341 ccgaaaaacc tactaaaggg agacatgagt gggttatcgg atcaagtgga cgctttttta
    74401 atgttcgaaa tcataccgat tgctgaactt attcaggatg cgtttaacgc tagtctctat
    74461 gaagtagaag aatacttgtc agggaatttt gtacgtgtgg atacaactat gatcaagatt
    74521 actagcttca aagatttggt tgacgctatt gatgtaggca ttagaaatgg agtatttaca
    74581 atcaacgaag gaagagaacg cgttggaaat gatcgctctg ataaggcgat ggcagatgaa
    74641 atatttataa ctaaaaacaa tcaacaagta tcgaaaggag gtgaggcgaa tgacgacaat
    74701 gaaaacattt ctagcagtaa agaatgaagg cgcagtaccg caaattttta ttcagggatt
    74761 tattggttct agttggttct ttgaagggaa tactgacaag ggaatcaaaa atattttgga
    74821 tagtctaggt gatcaagaag aaattgaagt agtaattaat tcaaacggtg gagacgtatt
    74881 tcaagggatt gctattggga acttacttaa gtcaaataaa gcaaaagtta acgttgtgat
    74941 taacggctta gccgctagtg ctgcttcaat tatcgcaatg gctggcgata ctataaaaat
    75001 ctacaacaat gcacaattga tgattcaccg cgcttccaca tacggagaag gaaatgtcga
    75061 tgacttccgt acgattgctg accaactgga atcaattgat aaatcggtaa aggcttcata
    75121 taaaacacga ttcaatggca cagatgaagc attgcaagaa cttcttgaaa aagaatcgtt
    75181 tatggatgca gaaacagctt tgagttatgg attggtcgat gaaattatcg atgcagaaaa
    75241 tagctcaggt actgaagcta aaaaagaaca aagcgttgaa gaaattttga atgacgttaa
    75301 agaaaaaaga gcagaaaaaa ttgctgcatt tacagcagca ttaaataaaa catttggaca
    75361 aggagatgta aaataatgac agttaaaaat ttaaaaggtg taacagctgc aagcgaccaa
    75421 ttgatgaaag cttttaaaga tggtaacgaa gaatctttta gcgcagctat ggtaagctta
    75481 tctaaggaaa ttcaggataa aattttagaa gaagcaacag caaaaaatca agatcaatta
    75541 gtattaatga accgtggtca gcgtgtatta actacacaag aaacaaaatt ctataacgaa
    75601 gtagtgaaaa acgaaggttt tgcaggggtc gaagaattag tgccagctac tgtatttgaa
    75661 cgtgtatttg aagatttaga acaatctcat ccactattgc aaaaaattac ttttgttaac
    75721 acaactggtg taacagaatg gattgtgtca cgtggagtca atccagcatg gtggggtaaa
    75781 ctttgcgaag ctgttaaaaa agttttagat aatggctttg atgtaattaa catgaagcag
    75841 ttcaagctat caggttatat tcctgtatgt aaggcaatgc ttgatttagg tccagtatgg
    75901 ttagatcgtt atgtccgtac tgttttagta gaatcattga gaattgcatt agaacaagca
    75961 attgttgatg gtactggtaa agatatgcca gtcggaatga tgcgtgacat gagcaaacaa
    76021 actagcggag aatatgctga aaaagaagca gaacctatta cagctttaga tgctgtaact
    76081 atgggcggtt tgatggcgcg actatcaaaa ttcaatatcg aaggtgtgaa tgatccgatt
    76141 tatcgtaatg tgaatccttc tgatgtggtc ctaattgtga atccaactga ttactggtct
    76201 aaagtattcc cagctaagac tgtactaact gctaatggag aatacgtaca agtattgcca
    76261 gtaccagttt cagatttgca gtcaacggct gtgccagaag gaaaagcagt tattggggta
    76321 gcctcagatt acttcatggg tgtaggatct acactaaaaa ttgaagcttc agatgaatac
    76381 cgttttgttg aagacgaacg catttatcta gctaaacaat atgcaaacgg tcaacctaaa
    76441 cgtaacgata gtttcattgt attagatatt agcgctttgg gaactactac tacaactaca
    76501 aaaccaacaa ccacaacaac tacaacacaa gcgtaggtga tcagaatgaa gtatattctt
    76561 tgtcagccgg caatcaatcg gtttaaatgg gagcttgaag tttgtttaac taatctgaag
    76621 aaactaggaa tcaaagatat cgtattgctt ttcagcagac acgatgatca gattcctatt
    76681 ttttttgaga aggaatatgg tgttgaagtt catgtgtacg atgatctgcg ggacgacaaa
    76741 gagtatattc cttcgattaa accatattta tggtggaaat atttagaaga agatcattcg
    76801 cgtgaggacg accgatattt ctatatcgat tcggatgtca ttttcaataa aagaattaat
    76861 ttgcgcaaat tgccttctaa agatgatgtt tggtattgta gcgactgctg tagttatcta
    76921 agtcttgatt atattagaag ctgtgaaaac ggagaaaata ttctaaaaga tatggcaaac
    76981 attgtaaatg ttacagtaga atctttggaa actataaaca ctaattcagg aggcgcacag
    77041 tgggttatta accgtcctaa agcgaattat tggaaaaagg tttatctgga ttctaatcgg
    77101 ctatatcgct accttagagg gcaaaaaaca aatatacaaa tctggacagc cgagatgtgg
    77161 gcacagcttt ggaacatgat gtatttcaat attggtccta aagttcacga ggaattagac
    77221 ttttgttttg ctactgatcc aatagaaaaa gttaaagaag taaaaatctt acacaatact
    77281 ggagtaacaa caaacgatga agatttattt ttcaaaggga gatacgtgac ttctacgcct
    77341 tttgatgaag atttatcatt tgtaaacaag aaaaaatgct cttacgcata tgttaaagca
    77401 attaaggcgg tggttagatg acgcctgaac aagtgactga agaattgcta atagctgtga
    77461 aggataatat ttacgttacc tggaacgaag aagatgagtc aattaaaaag atgatagcta
    77521 aaaatgctgt ttatcttcaa agtaaagtga gtacaacact ttctttttct cctgaaagct
    77581 tagaatacgg attgctaatc gaaagatgta gatacgactg gaatcgtgct ttagatgagt
    77641 ttgaacaaaa tttcgctagt gagttattag gtttcattca acattatgcg ctacaagaat
    77701 atattgcagg tgatgtgaat ggcgaataat cgtagactcg aagaaacatt caacgatggt
    77761 tggttaaaga ttttgacgca aactaccaaa agaaatgaac taggaaaaaa gattggtgta
    77821 gaagatacag aaatcacttc tttaaaattt agaaatcttt ccatgagaga tagtgatata
    77881 acagctatgg atgcgatggg atcgaaatta actaagaaag taaagactcc atttcatcca
    77941 atcgccaaga aatttaataa agatcaatat tttatcgtaa tcgatagtat gcgttacaac
    78001 gttatctatg ccgattacga taatttttat atctattttt atcttgaaag tgtgggtgaa
    78061 tatggtgatt gataattcta aagaaaaaga acgtttaaat aagcaaattt ctgctatcaa
    78121 aacttcctta gaagagcatt ttggcctcaa actctttcaa gactccgtag gcgaggatga
    78181 gctacctgat gattttaatt acttcattct cgaaacagga gaaatagaaa tgatcactga
    78241 gccaaaatat agcgtgggtc aaaatctata tctaactttc tattcagaaa atagagaaga
    78301 tttaacagga gattcactag atattatttc attgattcaa aatcgttcga ttcgttttca
    78361 gagaatggat cccaatcatt taaaactaga gaaccaagat cgctatatcg atcaattggt
    78421 atttacgttt agacgattat tgaagagtga ttgtcatggc taaaaatagt tgggagctaa
    78481 aaataaatgg acatgatgaa cttcttgtgc ggatggaacg ctattcaagc gagagcgaac
    78541 gactgattaa cgaagcattg aaatcaaaag gttcggctat tgcagtggat aggattacag
    78601 aaaaaattcc tgtttctgaa gcagatttaa gaagagggca ccaacacgca aaaaatagtc
    78661 gtccacttaa gactcaatac attaatttgg gtttcatcat tagacctaca agaaaatttg
    78721 agtatttaaa atatcctgat ttggggatag gtacttctaa aagaaatcag ccggacgaat
    78781 ttatgagaag aggattaggt cttgcacttg atccaattac agaacttctg attcgtcaat
    78841 tcgataaatt aaataaatag gaggaacaac aatggctaaa acaacaacag taacaacttt
    78901 tgacaatata agtattaaaa gaatttcttt taattttaag aatgcaacaa atgcaatttc
    78961 aactgattgt aatggacaat tagatggcga aacagaaatg cagagaattg taaaaaaatg
    79021 cggttcaaca gaagtaaaat cgaaatctaa accaatcaat atgacggtaa caattactgc
    79081 acatgtaccg atggaagttt atcgacgctt caatgggttg aaacaagatg aacgtattaa
    79141 atcgggaatt tactcttatg gtcctgattc cgtaggggaa gatttctcac ttgctgcaga
    79201 gatcgtggat gacttcgaag aaaatagaaa gttagttggt atgttagcat gcacttcgaa
    79261 tacaggatta acattctcta ttgaaaatgg tgcggatgaa gtagctgcgt tagaactaga
    79321 aacaaaagtt atgcaagatg aatttggtaa attttatcat gaagcaattg ttgcagaact
    79381 tgaagaagac ttaacagatc aatggatgac gaatctatct gctgatgtga ttaaaaaaac
    79441 ttcagttgtg acaactacgg ccactcaatc acagtaaaaa aaacggaggt agcgaaatga
    79501 acgaagatta ctcaaaaatt gaactaaacg atggaacaat tttgaattta gaacctaaac
    79561 tgaatatcaa gaaattattg atgatcaata gagattttaa cacagacgag tttgcaaaaa
    79621 tgactgtggg aaaaggatcc atggatattt ctgttattca aggtgcaaag gctgtgtata
    79681 ttgcttaccg ccaagcgaac atgactgatt atatttcatt cgatgaattt atcgataaat
    79741 gggattttga tatggctact gccagctata tttatcaatt gatgatgttc aaacaagcac
    79801 gcgatgctta tcaaaaagaa tttgaaaaag caaataagga aaaaaagctt caaaagtaaa
    79861 aattccaaag ctcttagttg aaacgtgggt cgatgtctat tcgatgttga ccgacgtttt
    79921 ttctatgcct tcagatttgg ttttaagcga tatctgttta gatgacattt tgcaaatggc
    79981 ttacaacaag agtgcttatg aaggatggaa aaactatgca ataaaccaat cccagaaaaa
    80041 ctaaagaaag gaggtaaaaa atggctaaaa agagaacaga agcagaagta actttcatag
    80101 ctaacgatga cggattgaaa tctacgttaa aagaaatcag tgctgaatta actaaaaata
    80161 gagcagaatt aaaactagaa caagctcaat tacaacagac tggttctgaa tcagacaagt
    80221 taggaagtaa attatcttct ttagaaaagc agtatgaatt acaaagtcaa aaagttgaag
    80281 taactagcca acgtttagcc aatgcgaaaa aatattatgg agaaaattcc accgaagttc
    80341 agaaacttga aagagaactg attaatcaac aaacagcgca acaacgtttg tcaaacgaaa
    80401 ttgataaaac gagtaatgca ctagctcaag caaaaggcga aatacagacg tacgagtcta
    80461 caatgcaaca gttggatagc gaacaaaaaa atgttcaagc tagtgcttct ctgattgaat
    80521 ccgaatacaa aaaatggcaa gcaactgctg gtcaatcagc ttctgaagcc gagaaattag
    80581 cgaaagccca agaatatgtt tctcaacaat ctgaaaatgc ggagaaaacg atagatatcc
    80641 taagacgaca gttagaagct acacagtctg aatttggcgc tacatccaca gaagcaatgc
    80701 agatggaagc gaagcttaat gatgctgaac gtgaatttga agagttagga caagctgcta
    80761 aaaatgtaga tacaactaac ttggacgata tcggaagcaa aatagatatg aataatttaa
    80821 tggaagcttc tgacgtttta agcgacattg gcgataagct tacagaatta gggaaacaag
    80881 cagtggactc tgctaacagt gtaggtagtt cccagagtaa gatacaagct aattttggtt
    80941 tgtctaaaca agaggctgaa gaattaacga atgtagccag agacatttat tataaaggtt
    81001 ttggagaatc gttagatcag tccacagatg cattgatttt ggtaaagcgt aatttaggag
    81061 atttaaataa tcaagattta caaaatatca cggaacaagc tatggtccta gaaaacacca
    81121 tgggcgctga tatggatgaa acgttacgtg gtgtaaatgg cttaatggtc aatttcggct
    81181 tgagtgctca agatgcaatg gatttaatgg tttcgggtac tcaaaacggt ttagataaaa
    81241 cgcacgaatt aggcgacaat atggcagaat atagccaatt atggagtcaa atgggatatt
    81301 cagctgatga aacgttcgga atgcttcaaa atggtttaga tgcgggtgct tataaccttg
    81361 ataaagtcaa tgacttagtt aaggaaatgg gaatatcgtt aacagatggt cgatttgagc
    81421 aaaacatgga tatgtttagt gaaagtacta gaaaagcttt tgaagagtgg aaaaatggcg
    81481 gaggaacaca aaaagacgtt attaattcca tgattcaaga ttttagcaat atggatggtc
    81541 aatacgacca attaaataaa gcttcgacaa tttggtctgc gcttggcgaa gataatgcga
    81601 tgaaagttgt ccaatcttta actgatgtta accatacatt tgatgatgtt agtggatctg
    81661 cacaaaaaat gaatgaagat tctactactc cgttacaaga attaaacgga aaaatagctg
    81721 aattaaagga ttcattagct cctataggca acacaatcat agatgcactc gaaccagtaa
    81781 ttgattttct aggaaagatg gctgatgcgt ttaataatct tccacaacca gtacaggatt
    81841 atgccgtagc gattggcgga ttgactgctg catttacttt attaatgcca ataatagttg
    81901 gcttcatggc tctaggtggt cctactacat taataatagg agcagttatt actgctattg
    81961 ctggagttat agcaattata aaaaactggg gcgcaatcac tgactggttt agtgatttat
    82021 ggaaaaaatt taccgattgg ttaggtgata cctgggaaag tataaaagaa agtgcctcat
    82081 cagtttggga tggagtcaaa gaaacctggt ctggatttgt agattgggtt caagaaattt
    82141 ggcaaggagt ttctgattgg tttggagagt tatggagcgg attagttgaa ggagcttcca
    82201 acatctggca aggagtccaa gagacttggc aagcattcgt tgattgggtt tcaaatattt
    82261 ggaacggagt caaagaagta tggtcgatta tttgggcaga cattgtagga attgttcaaa
    82321 taccatggac attaataacg tcattgattc aagctggtat taatattatc gtgggtatct
    82381 ttgatgtagc tggacagtta ttaggcgcag cttggcaagc tgtttggaca cctatttctg
    82441 atttccttaa aaatacttgg gatactatga cacaatggat aagcatcgct tggaatggaa
    82501 ttgtaactac attccatact atatttgatc cagtagtggc atggtggaat ggtatatgga
    82561 catctattag tactacggct tcaaatattt ggaattcaat tagtgcaaca gcttctagta
    82621 tttggaacag tatcaagaat acaatcacta gcttggtaca agcagctgct acagtaattc
    82681 aaaatatttg gtcaactgta tctagttggt taggtggaat ttggaattca atcagctcta
    82741 cagcatcaaa tatctggaat agtgtgacta gtagtataag caatgctata aacgcagcta
    82801 aaagtgccat tcaaagtgtt tggaatagta tatcttcgtg gatcagcgga atttggaacg
    82861 gtatcaaaaa tactgctttg aatctttgga atggaattac aagcactatt agctctaaag
    82921 taaacgatgg aaaaaatgca atttcaagcg gttggtccaa tctaacaggt attgtttccg
    82981 acatattcaa taatgttaaa agtacaattg ctaacatatg ggaaggcatc aaaaagactg
    83041 ttagcgctcc aattgattgg attagagaca aaatcagtgg catttttgat aatttgaata
    83101 tttctatacc acatattccg ttaccggaat ttatcatgga aggcagcttt aacccgctaa
    83161 aaggtcaaat cccccatttg cgtgtaaaat ggcatgctaa aggaggtatc tttactaaac
    83221 caactttact aggtggaatg aacggtgtcg gtgaagcagg acctgaagca gttttacctt
    83281 tgaaaagatc tgttttgcaa gaaattggtg atcgtatctt gagtagcaca tcagtttcat
    83341 ctagggcaca aacgattcaa cctgtgaata actacgaatt caatttcaca attgatggta
    83401 acgcagatga ggttactatg aagcaaacaa ctcaacaaat cattgatagc attacaaaaa
    83461 ttcaaaatga taatgcttcg gcatggcgtt aaacaggaga gtatttctcc tgttttttta
    83521 gtattaaaaa ggatgtgaaa aaatgactga ttgtatacat tctataatcg atggatttcc
    83581 tgattatttg cataaattgg ctttagctga aagaccaacc ataccttctc caaaaagaca
    83641 gagagttgaa acttctgttt taggtaggtt aggtggctta gtacaagatt actcgtttga
    83701 agatatgtcg tttacattgc actataacta tttagaggat gtggaagacc atcaagcgtt
    83761 caagcaatcg ttttatatca tgcgtcattg gttaaactat gcaaagaaat tagaattctc
    83821 tgacgatccc aacgtctatt acgttatcca gactatcgat attggggatg cagaaaacga
    83881 tattgttgaa tggggagagt tcgatgtaaa tattactgcg aaaccattcg caagagttca
    83941 agaagatgta cctataaccg tagataaacc acagtcattt aacttgctga ataatagttt
    84001 agaagaaagt tttccaaaga ttatcatcac tccttcagct acttcatgcc agttcatctt
    84061 aaatgattat gtgtttagtt tcgaaggctt agtagcagga actgatgtag tcattgatag
    84121 tgatttgatg ctttgctacg aagagcaatc ggacggagat attttagatc ggtccaacaa
    84181 aatgaagacc atgcaatatc caacgttgca agtggatatt aatcatttta attgtactgg
    84241 tttgagcaaa atacaaattt atcgtaacgg gttaaggtag gtgaaataga tgatcgataa
    84301 tttaataact atttacgata aaaatgacgc gaataattta gctgaacatt tatatgatac
    84361 gcaaggttta ggcgctttgt cagactggtt aacagctact gttagcaata aactaaacgg
    84421 agccgagata tttcagggta cttattcaat aaacggaact aatgcagatt tgattgtaga
    84481 aggacgtatt attcagtgtt atgtagatga aaatcgagca aaacagcgtc tacggattta
    84541 ttatgcaaaa acttctgtaa taggcaatac gatagaagta aaagctgaac ctattttcaa
    84601 tgatataaga aaatcggtgt tgaataaata tgacagcgga acagaaaaga tcactgctac
    84661 tcaggcatgg caaaacgcaa aagttttagc gaaaccagct atcccttcgc agttttcttt
    84721 ctcgtcatta gtagatacgc ttgctaatgt gaagatagaa aaggcgaatt ttttagaatt
    84781 ctttggtgga aaagagggat ctattctaga tcgatttcat ggtgagtttc taaaagataa
    84841 taacacatta cgtcatgaaa aaagtctagg tacggatcat aaaatcaaag cgatttatac
    84901 taaaaactta actggtcttg acttagagat tgatgctcaa agtgttttag ttggagttta
    84961 tccattcatt agcagctctt cagaaggaga agacgagatc actctaccag aagaagttat
    85021 tttcacggat tacgtggatg attatcctgc tggatatgtt tcttttgttg attttaaaga
    85081 caaagcgact gatgtagcca cattaaggga agctgctaaa gactggttga aaacaaacat
    85141 agataaacaa aaaccacaag tgagtggttc gattgaatta gtaccattga ggcatcaaag
    85201 aggctatgaa aaatttgttg atctagaaaa agtttcgatg ggtgacggag tagatgtgta
    85261 tcatccacag ttaaaagtga atatgtcagc gagaattgtg gaatatacgt ttaatgttct
    85321 aaccaattca tacgataaat tagttgtagg aaacgtcaaa acaaacttct tagaaaacac
    85381 agagaataat gtcagcaatt tgattaatga tgccattgat caattgaaaa atggtggcga
    85441 aatcagtgat ttaatcaatg atattgtaga tcatcaaact gatatgatta ctggtcaaaa
    85501 tggtggttac gttttattag atcctaaaga agcccctagt cgtattttga ttatggacac
    85561 accagataag aatactgcac ggaacgtttt gcaaatcaac aacgctggta ttggtttctc
    85621 taaaactggc attaatggaa cgtatgacac cgcatggacg ttagatggcg gattcaatgc
    85681 ctcgtttatt acagctggtg agatagtagg gattactatt agaggtacta cattaattag
    85741 tgatggcact gattatagaa caagtatagc taatggcaaa atgacttggt actcaaaaaa
    85801 agttaacaaa gatattatgg agctagaagc acgtgattat gtaagtgctg atgccggcat
    85861 tgtatcatac accatgaaaa ctggtggtgg tttcatgatt agaaatccac agggtaactt
    85921 ggtttttagt acgtgggata atggtaataa cagaccgttt ttatcttttg gtgcgccaaa
    85981 tttcagatac agtaatgcta gttatataaa tgatggtgac ggtaattctt taggtattga
    86041 tggtagtgca ggtaattcat gggaatttaa agtagctggt aggactatga aatttactag
    86101 tgacggtatg ctaacgttgc caggttgttt ttttggttca tgggaagatg ggaaacttgc
    86161 tagatttgaa caatcaacgg tacaagtata taaagatttt actgttagag gtactaaaaa
    86221 ctcaaccgta ccaacagaac attatggaca acgactattg aacgcttatg aaactccaga
    86281 atattatttc gctgattatg gggaagccgt tacaggtgat gatggtaaag ttcgtgttga
    86341 tattgacccc atgtttgctg agacagtaaa tctaagtcgg tatatgacac atgtgacacc
    86401 tacagaacta gttttgtgtg ctgttactca tgaagatgtt gaccatttca tcattgaaac
    86461 tagtaagcca aacgtattgg ttagatggaa tttagtggca catcgactag ggtatgaaga
    86521 tgttagatta aaagaggata cagcatatga tagcacagtg cttgaccaaa aacgttttta
    86581 aaacgaagac aaggaggtat ataaatggct agcagtttat ataatttggc tttagatttc
    86641 agcaaagaat taaactacac caaagctatt atggctcgtc aaggtgataa agggatcacg
    86701 gtgactgtta aaccgttttt aaatggcttg cagatggata cgagcggcgg aacatttact
    86761 ttaaaaggaa ctacgccatc taaccgttac gtagatagtg tcgctactag tgtaactagt
    86821 gaagaagtca cattttctct tgatggcaca tttatgagtg aagcagggta ttataaacac
    86881 tgctatgtag aatatagaaa agacgatcaa attttaacga cgcaagatat catttttttc
    86941 tcactaggag tgtctgacat ttcgcaaggc caagccgatg aatatgtttc gcaattagaa
    87001 gaattgattc gaaagtataa cgaaactttt gatgcttttc tggctgaaat taaaggtaga
    87061 atggatagct taaataaaca gattactgat ttaactggtc aagctaaaac actacaagac
    87121 aagttagatg ctctgaaaga agaaatttct aaattaggta acttacatgt gatgtactcc
    87181 aacagcatcg acttcggggg ctatgattat agtgggaatc cgaatttaat gtccaaacta
    87241 aaatcgagcg attttaacgt tggttaccac gggtcactaa ctaatgttaa cggaatgtta
    87301 cattttatgt ctgatggtac aggggacatt gatatgttta cgcgtattaa tacacctcag
    87361 cttgctagtg gcaaaacata tactctgagt gcaaaagttc gatttgatga aggaactaca
    87421 ggagctatta ataaattacg tttggtatat cgtacatcac caggagaaaa tatattattg
    87481 gaagcaaata atacaactat tacaatagat gatgtaggga aagaaataac aatcaaaggc
    87541 acagctaacg ttaattatca aatcacaaat ttagatcgtt tttatattag tgttagtttt
    87601 tctaacaggg ataaaataaa tggtggattt aaattgtacg acatcaaaat cgaagaaggc
    87661 tcaacagcca ctccgtatca gccaaactta ctagatgacc cttactgggt aggtaaaaca
    87721 tcgttgggta agaatattgc aaataaaggt acgacgttcc caattaaatc tagcgcgtac
    87781 gaaatatata aaggtaacac ggaagaagag cttataatag gtcaaacgta tactatcacg
    87841 cttaaaggaa caaaacccgc aagtcaaacc tttgtagcat ataattattg gaacgttaat
    87901 tttggagatc taaaaccagt tgagggattg acagacgtat ggtctctaac attcacacca
    87961 acgaaacttg aaccgggttt gcctaaagac cttcgcattt ttcagtcgcc taaagaaacg
    88021 gccggcgcat gccgaattga ctggctcaag atcgaaaaag gcgacacacg aaccccgaat
    88081 attgagcaat ataaataccg aggaatcggc atgcgagact caaacaatcc aaaagattat
    88141 gtatgggatc tagaacctag ctatgttgag aataacctag ctacagatat caaggttgct
    88201 gaaatcacag gtaaagcaaa caattatacc gatgggaaag tatcggagat taattcgcag
    88261 ttgactgctt caattaatga agtagacacc acagctaagg atgctcaaac aaaagcgaat
    88321 gctaatgcga ctgctataga tgaattagac aataagatcg atgaacgcat taatgataca
    88381 gctactacca cattaacagt tacaaacggg aataccggat cagcaaagct ttatcgtgaa
    88441 ggaaaaacag tttctatata ttttgtggct ttaaacggaa aaagcagtgg tggaaatgat
    88501 tcaacgatac taacaattcc agaaggctat cgg
//
LOCUS       DACCVZ010000002        76172 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.002, whole genome shotgun sequence.
ACCESSION   DACCVZ010000002 DACCVZ010000000
VERSION     DACCVZ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 76172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76172
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.002"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(68..1489)
                     /locus_tag="IVW63_000108"
     CDS             complement(68..1489)
                     /locus_tag="IVW63_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7858413.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1732..3609)
                     /gene="tdc"
                     /locus_tag="IVW63_000109"
     CDS             complement(1732..3609)
                     /gene="tdc"
                     /locus_tag="IVW63_000109"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAP7858414.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3900..5156)
                     /locus_tag="IVW63_000110"
     CDS             complement(3900..5156)
                     /locus_tag="IVW63_000110"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAP7858415.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     gene            5736..7037
                     /locus_tag="IVW63_000111"
     CDS             5736..7037
                     /locus_tag="IVW63_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAP7858416.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7106..7705)
                     /locus_tag="IVW63_000112"
     CDS             complement(7106..7705)
                     /locus_tag="IVW63_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7858417.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            7960..8841
                     /locus_tag="IVW63_000113"
     CDS             7960..8841
                     /locus_tag="IVW63_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7858418.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            8854..10464
                     /locus_tag="IVW63_000114"
     CDS             8854..10464
                     /locus_tag="IVW63_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HAP7858419.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(10541..11200)
                     /locus_tag="IVW63_000115"
     CDS             complement(10541..11200)
                     /locus_tag="IVW63_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP7858420.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(11483..12148)
                     /locus_tag="IVW63_000116"
     CDS             complement(11483..12148)
                     /locus_tag="IVW63_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858421.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(12295..12900)
                     /gene="dhaL"
                     /locus_tag="IVW63_000117"
     CDS             complement(12295..12900)
                     /gene="dhaL"
                     /locus_tag="IVW63_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HAP7858422.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(12928..13911)
                     /gene="dhaK"
                     /locus_tag="IVW63_000118"
     CDS             complement(12928..13911)
                     /gene="dhaK"
                     /locus_tag="IVW63_000118"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAP7858423.1"
                     /translation="MKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRVVAKNQKAEQ
                     VGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEADSGKGVLLIV
                     KNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAGTVLVHKIVG
                     DAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDEIEYGVGIHG
                     EPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQFVFMNDVLA
                     LLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTISW"
     gene            complement(13913..14308)
                     /gene="dhaM"
                     /locus_tag="IVW63_000119"
     CDS             complement(13913..14308)
                     /gene="dhaM"
                     /locus_tag="IVW63_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HAP7858424.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            14462..14782
                     /locus_tag="IVW63_000120"
     CDS             14462..14782
                     /locus_tag="IVW63_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAP7858425.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(14894..15763)
                     /locus_tag="IVW63_000121"
     CDS             complement(14894..15763)
                     /locus_tag="IVW63_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP7858426.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(15859..17163)
                     /locus_tag="IVW63_000122"
     CDS             complement(15859..17163)
                     /locus_tag="IVW63_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP7858427.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(17160..17669)
                     /locus_tag="IVW63_000123"
     CDS             complement(17160..17669)
                     /locus_tag="IVW63_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858428.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(17844..19979)
                     /locus_tag="IVW63_000124"
     CDS             complement(17844..19979)
                     /locus_tag="IVW63_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7858429.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(20062..21717)
                     /locus_tag="IVW63_000125"
     CDS             complement(20062..21717)
                     /locus_tag="IVW63_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP7858430.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(21719..22033)
                     /locus_tag="IVW63_000126"
     CDS             complement(21719..22033)
                     /locus_tag="IVW63_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP7858431.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            22203..22463
                     /locus_tag="IVW63_000127"
     CDS             22203..22463
                     /locus_tag="IVW63_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAP7858432.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            22477..22791
                     /locus_tag="IVW63_000128"
     CDS             22477..22791
                     /locus_tag="IVW63_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAP7858433.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(23521..24075)
                     /locus_tag="IVW63_000129"
     CDS             complement(23521..24075)
                     /locus_tag="IVW63_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAP7858434.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(24201..26130)
                     /locus_tag="IVW63_000130"
                     /pseudo
     CDS             complement(24201..26130)
                     /locus_tag="IVW63_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(26436..27152)
                     /locus_tag="IVW63_000131"
     CDS             complement(26436..27152)
                     /locus_tag="IVW63_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAP7858435.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(27153..28976)
                     /gene="glpO"
                     /locus_tag="IVW63_000132"
     CDS             complement(27153..28976)
                     /gene="glpO"
                     /locus_tag="IVW63_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HAP7858436.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(28990..30486)
                     /gene="glpK"
                     /locus_tag="IVW63_000133"
     CDS             complement(28990..30486)
                     /gene="glpK"
                     /locus_tag="IVW63_000133"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAP7858437.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(30622..32082)
                     /locus_tag="IVW63_000134"
     CDS             complement(30622..32082)
                     /locus_tag="IVW63_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7858438.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(32072..33367)
                     /locus_tag="IVW63_000135"
     CDS             complement(32072..33367)
                     /locus_tag="IVW63_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP7858439.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(33699..34376)
                     /locus_tag="IVW63_000136"
     CDS             complement(33699..34376)
                     /locus_tag="IVW63_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HAP7858440.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(34406..35497)
                     /locus_tag="IVW63_000137"
     CDS             complement(34406..35497)
                     /locus_tag="IVW63_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HAP7858441.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(35598..36032)
                     /locus_tag="IVW63_000138"
     CDS             complement(35598..36032)
                     /locus_tag="IVW63_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7858442.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(36616..38073)
                     /gene="ascB"
                     /locus_tag="IVW63_000139"
     CDS             complement(36616..38073)
                     /gene="ascB"
                     /locus_tag="IVW63_000139"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP7858443.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(38070..39965)
                     /locus_tag="IVW63_000140"
     CDS             complement(38070..39965)
                     /locus_tag="IVW63_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7858444.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(40023..41798)
                     /locus_tag="IVW63_000141"
     CDS             complement(40023..41798)
                     /locus_tag="IVW63_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP7858445.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(41848..43344)
                     /locus_tag="IVW63_000142"
     CDS             complement(41848..43344)
                     /locus_tag="IVW63_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP7858446.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(43538..45160)
                     /locus_tag="IVW63_000143"
     CDS             complement(43538..45160)
                     /locus_tag="IVW63_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAP7858447.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(45488..46801)
                     /locus_tag="IVW63_000144"
     CDS             complement(45488..46801)
                     /locus_tag="IVW63_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP7858448.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(47046..47270)
                     /locus_tag="IVW63_000145"
     CDS             complement(47046..47270)
                     /locus_tag="IVW63_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858449.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(47290..47658)
                     /locus_tag="IVW63_000146"
     CDS             complement(47290..47658)
                     /locus_tag="IVW63_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP7858450.1"
                     /translation="MIQKTRVMLYVNDVEMICRFFVEKIGAEISETIELPEEFKSIVL
                     SISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETIYENMEEPGEITDNNGILT
                     FNFSDPEGNYFVIGKAESSD"
     gene            complement(47854..48564)
                     /locus_tag="IVW63_000147"
     CDS             complement(47854..48564)
                     /locus_tag="IVW63_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858451.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(48582..49079)
                     /locus_tag="IVW63_000148"
     CDS             complement(48582..49079)
                     /locus_tag="IVW63_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7858452.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(49116..49568)
                     /locus_tag="IVW63_000149"
     CDS             complement(49116..49568)
                     /locus_tag="IVW63_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7858453.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(49703..50308)
                     /locus_tag="IVW63_000150"
     CDS             complement(49703..50308)
                     /locus_tag="IVW63_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAP7858454.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(50758..51378)
                     /locus_tag="IVW63_000151"
     CDS             complement(50758..51378)
                     /locus_tag="IVW63_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7858455.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(51380..52249)
                     /locus_tag="IVW63_000152"
     CDS             complement(51380..52249)
                     /locus_tag="IVW63_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HAP7858456.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(52272..52679)
                     /locus_tag="IVW63_000153"
     CDS             complement(52272..52679)
                     /locus_tag="IVW63_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAP7858457.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(52698..53987)
                     /locus_tag="IVW63_000154"
     CDS             complement(52698..53987)
                     /locus_tag="IVW63_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7858458.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(54014..54316)
                     /locus_tag="IVW63_000155"
     CDS             complement(54014..54316)
                     /locus_tag="IVW63_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7858459.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(54341..56434)
                     /locus_tag="IVW63_000156"
     CDS             complement(54341..56434)
                     /locus_tag="IVW63_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP7858460.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(56923..57687)
                     /locus_tag="IVW63_000157"
     CDS             complement(56923..57687)
                     /locus_tag="IVW63_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HAP7858461.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(57798..58667)
                     /gene="mdcB"
                     /locus_tag="IVW63_000158"
     CDS             complement(57798..58667)
                     /gene="mdcB"
                     /locus_tag="IVW63_000158"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HAP7858462.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(58692..59768)
                     /locus_tag="IVW63_000159"
     CDS             complement(58692..59768)
                     /locus_tag="IVW63_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAP7858463.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(59792..60385)
                     /locus_tag="IVW63_000160"
     CDS             complement(59792..60385)
                     /locus_tag="IVW63_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HAP7858464.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(60389..62065)
                     /gene="mdcD"
                     /locus_tag="IVW63_000161"
     CDS             complement(60389..62065)
                     /gene="mdcD"
                     /locus_tag="IVW63_000161"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HAP7858465.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(62055..62354)
                     /locus_tag="IVW63_000162"
     CDS             complement(62055..62354)
                     /locus_tag="IVW63_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HAP7858466.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(62456..64102)
                     /gene="mdcA"
                     /locus_tag="IVW63_000163"
     CDS             complement(62456..64102)
                     /gene="mdcA"
                     /locus_tag="IVW63_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HAP7858467.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(64109..65020)
                     /locus_tag="IVW63_000164"
     CDS             complement(64109..65020)
                     /locus_tag="IVW63_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAP7858468.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            65140..65997
                     /locus_tag="IVW63_000165"
     CDS             65140..65997
                     /locus_tag="IVW63_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP7858469.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(66184..66546)
                     /locus_tag="IVW63_000166"
     CDS             complement(66184..66546)
                     /locus_tag="IVW63_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858470.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            66892..68331
                     /locus_tag="IVW63_000167"
     CDS             66892..68331
                     /locus_tag="IVW63_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP7858471.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(68338..70890)
                     /locus_tag="IVW63_000168"
     CDS             complement(68338..70890)
                     /locus_tag="IVW63_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HAP7858472.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(71004..72335)
                     /locus_tag="IVW63_000169"
     CDS             complement(71004..72335)
                     /locus_tag="IVW63_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7858473.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(72301..73779)
                     /locus_tag="IVW63_000170"
     CDS             complement(72301..73779)
                     /locus_tag="IVW63_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7858474.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(74084..75919)
                     /gene="tdc"
                     /locus_tag="IVW63_000171"
     CDS             complement(74084..75919)
                     /gene="tdc"
                     /locus_tag="IVW63_000171"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAP7858475.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
BASE COUNT        21785 a        16167 c        13055 g        25165 t
ORIGIN      
        1 aaactattca cttggcagga cctcctacta aatcagcgac aaaacgtcgg ctgaaagact
       61 tattttttta tttttcttct aaactttttt ctacctcaat cccccaagaa tctttcttga
      121 agtgattgat gatcaatgga ataacgaaca tgaccactgt gatagctgct actaataatg
      181 catcactcaa tgtcgctgta cctaatgtag caaatacgac aacgatgata gagaagatca
      241 gcatgcagct gactacccaa gctaatccgt ttccgttttt accaattcgg taaggacgtt
      301 cgaattctgg atgtttctta cgcattttaa gcaatgaaac agcaatcaaa atgtacacga
      361 tacaataaat aacagttgta gcatttgtaa gtgtcaagaa tacagcactt acgtcatcca
      421 ttacaccata aagcaaagca aataatgaaa taacgattga ttgtgttaga acgacatttc
      481 tagatacgcc gtatttgttt tctttatgga atccgaattt tggtggaagg aatccttcac
      541 gagctacttg gatgattgtt tttgatggtc cagtaaccca agctgataat tgtaaaagca
      601 caccaataaa taccatgaag ctgaagatat ttccgatcac ttctggtaag cctaggattt
      661 gacagtcaat caagataggc tgcgtgatat ttgctaattc catttttcca tctggtacga
      721 catttgctac aagcatcgca ttgatgacat tcaataaaac taatccgatc aaagcgataa
      781 atacgccttt tgtataattt tttgttgcgt ctttcaaacg aggcatgtaa acagaactca
      841 tttcgatccc aacaaaaata aatgtgatac cagctaagta tttcaatgaa tcaatatgtt
      901 ccaagtcagg gaaagctttt gaccatgaaa agtcacctag atagccgttt gagactagtc
      961 cgactttgaa ggctgccaaa acacctaaaa cgaacatgat gactactggg atatataccc
     1021 ctagccatac accgatgttc ccgccgactt ttgccatatc gaatttcaag ttcaagatcg
     1081 tgatgatcca gtagataact aaaatacaac ctaaaacgaa ccagtgatta ttgccaagtt
     1141 ctacattacc aaatgtgttt cctaacaatg gtcctaaagt agaagcgacc attaccatac
     1201 ctgggaacat ttgcacccat aatagccatg caacgacaaa tccccatttg ctgcccagtg
     1261 ctgtttttac ccataactga ggaccgcctt cttgaggaag catcgtggaa agctcaccgg
     1321 aaaccattga tatcggaccg gcaaaaaaca aaactgcaaa aattgaataa aaaatcaatg
     1381 tccaaccgac tgcggctaac gtaggaatac tccgaaccgt tgcacacagt gccattgtca
     1441 gaccgataaa ggtcccaaga cccattttac ttacttcaga tttactcacc gttgacactc
     1501 tccttgattt tttggataaa ataacggtgt ctttgaagta gtttcagcaa taaacgaaac
     1561 aattcagcga atatttgagg ggattctttg agtttattgc ttgaagggtt tcttcaaaga
     1621 caacctcaaa acaaagggat cgaagagctt aggtctcccc ttgctcttca gatccaaaca
     1681 tgcgtcagaa acagttagta ttcaagctgt tttctaacat gattaccttg cttattttgc
     1741 ttcgcttgcc aataattggt ctgcgtagat tttttccaat ttttcttgaa gagctgcttt
     1801 gattttttca gcatattctt caaagtgttc ttctttgttc atgtatggtg tcattacgct
     1861 ggcacgcaat acagttactt ttccggcacg gttccattct tcatctgaga atcctagttg
     1921 gttcacaaat tgtaatgggc tgttgccata gtctgggata gcaaagtcag tatgtgaagt
     1981 taagaactca ttaccgtaaa tgcttccttt cacgtatgaa gaataatcat atacgtcatg
     2041 gttcaattta ttcattgcaa ctaagtcatc gttgcctttt tctttgaata catagtctac
     2101 catattgaaa tctggataag ttaatggatg aacttcgatt tctttgtctc ctactttaaa
     2161 tgacaagtca ttcaagaagt tgtagaaacg atgtgcacct tcgattgatg cacccattaa
     2221 tttaccatat cctgtgacat tcaaaggtaa gacatggtgt gctgcccaaa cgctggctgc
     2281 tgttgcccct gcttttgaac cttccaagat ataagcccca agtaatgctg ggatatctgc
     2341 gcctttttca aatacatatg tcgcaaagta agagataacg tctctcatgc ggatatcttt
     2401 gatgacgata ccaccggcag aatatggaac atagcccatt ttatgtgggt caatcgttac
     2461 agattctgct tcttcgattg ctttatatgc actgtgtact tcttctaaga tataatcttt
     2521 gttttctgta aagacattgt atttgtaatg aacatctttt aaatcttcaa atggaatgaa
     2581 gttgttgtct tcgtctaaga aaatcgcacg gccgtatccg ccataagcag catctacgtg
     2641 taagtagaag taaataccgt ctttttctaa tacgcgacgc aatgcaacga ttttatcgat
     2701 accgtcgatt gctccttctt ctgttgatcc tacaacaccg actacaccta ggattggtgt
     2761 tttttcagct gctagaccac gaacgatttt ttcaagttcg ttgatgtcca tgcgatagtt
     2821 gtggtcaact ggcactggaa tcacttggtc taaaccgata ccgatgatgt cggcagcttt
     2881 tagccatgaa tagtgtttag tttgtggaac caaccatttt cctaattttt ctaaatgttt
     2941 tccgctacgt gctgagtgag ctttgatttc gtcgattttt tctgggacgc tgtctaacag
     3001 attcatgatt tcttctgttg acaagttcat taattcccaa tcgctttttc cagcaactag
     3061 ttcaggtgtc acttctttca ttgcaagcgg caatgatttg atgttgcggg cataccaaag
     3121 tccttctaag tttgctaaag aaccatcagc aacgatgtgg ccccagccat ctttatagct
     3181 cattaatttt gcaaattcca ttcctacttc ttcttccatt tggcttgttg caggagaaga
     3241 ttcataggca acgttattac cattccatag catagcaaaa ttgtacgcta gtaaagatgg
     3301 catcaatgtt tcagagttca tatgacccca gtaacgtccg gcattatgcc aaggaacgga
     3361 atgggtacgc atccgcgctg aaatttctga tagaacatcc tttgttttat tcacagtgtg
     3421 ttcaaaacta gcactgcttt tttcttctgg cgtaataata ggcatgtctt gaggcatgta
     3481 gttttgacgc cagcctaaat gttcatccac caattcattc aacaaagctt tatagatttg
     3541 gccgttctca gctttgtccc caatgaatag ggcatttagg tttagatctt tcgacaatga
     3601 ttcactcata gtgaaaccct cctaaaaaaa tatttaaatt ttgtcgagcc ctacattaca
     3661 cctgttcttc tattctgtaa actaagtttt ggcctgattt ttaatcatat tttaatatgt
     3721 atcaattatc cgaattgttc acacttttga aataattaaa aaaaacgagg gaatttacaa
     3781 atgtaaactc cctcgcaaag attgtattaa cgacaaccag cgttctattt taggatgggt
     3841 ttcaaaattg gaatgttgta atagtatttc cctttttcaa ggtaaaaact tactaaattc
     3901 taatcaatta ctttggccaa aaagtaattt ttcttacctt ttcgaataac cacaaactta
     3961 ccatcgaatt catcggatgg atttatgaca aaatttaaat cggtaacgcg gtcaccgtta
     4021 atacttatag ctccgtttga aacatcttca cgtgcttgac gtttagatgg ttcaattttt
     4081 gtggaaacaa gcagttccac gatattttca ggtgtgcttg aaatttcaac gttcggcatt
     4141 ttaccgaatc cttgcgcgat ttcttccgca tttagttctt taatatttcc agagaacaat
     4201 gcttgcgtta ttttttgcgc ttctttcaag tcttcttcac tatgcacaaa tcttgtaact
     4261 tcttctgcca aacggcgttg tgcttcacgt ttctcaggtt ctgtctctac ttttttcgct
     4321 aagtcttcga tttcttcttg agacaagaaa gtaaagaatt tcaagtattt cactacatcg
     4381 cgatcatctt gattcaacca gaattggtag aactcaaatg gtgaagtttt cttcggatca
     4441 agccaaacgg caccgcctgc agtttttccg aatttcgttc cgtcagcctt cagcatcaat
     4501 gggatcgtta aaccgaacgc ttctgcttct ggtccttcta attttcggat taggtctaat
     4561 ccagctgtga tatttcccca ttggtctgct ccaccgattt gcaattgcac atcgtatgtt
     4621 ttatgcagat gcaaaaagtc gatagattgc aggatttggt aagtaaactc tgtaaatgag
     4681 attcctactt ccaaacggct ggcaacgata tcttttgcta acatcgtgtt gatgttgaag
     4741 tttttaccgt agtctctcaa aaattcaagt aaagagattt ttgacaacca gtcgtagttg
     4801 ttcacaaatg tgatatttgc atctttacca aacaattttc tcatttgatt ggaaagtgcg
     4861 tccacgttat gttgcacttg ttccatcgtt tgcaacacac gttctgtttt gcggccgctt
     4921 gggtcgccga tcgttcctgt tccgccgcca atcagaatat atggatgatg gcctgccaat
     4981 tggaatcttt tcatcatcat aaatggaatc aaatgtccga tatgcatcga atcaccagtt
     5041 ggatcaacgc cgcaataaag tgaaatgctc ttttcttcaa cgagctcgcg aagtctttct
     5101 tcgtttgttt gctgattaat ggcgtcgcgc caagttaatt catcaataat attcatttta
     5161 ctgacctccg tgtagttttt ttatgaaagc aggaacctgc tagcatgtgt aattaattat
     5221 ttcttcagga taggatagga aataaaaaaa gtcccttggc atataagcca agggacgaaa
     5281 tctcgcggta ccacccaatt tgtatgtcta gatatccaac atacctctcg aacatttaac
     5341 gctgtcgcgt ggcaatcact gccaaagact cctgaaatgt aattcgcttt aaagcatgta
     5401 ctggtttgca gcgaccacca gctttctgaa acattggctt taacaactac ttcgtttcga
     5461 tcttcgtctt gttattatta atatgtgtct atcatagagc gcaacttttt ctttgtcaac
     5521 agaaaaagga tatttttttt aaattcctca ttttttcttt tttgaatccg ctctaattcc
     5581 gaacatttta ttttcaatta ttgttaaaag aaataacttt ttctgtattt tttctgcaat
     5641 ttatcgagaa gtcactttac tttgcctctt attctttctt cgttacaata aggaatggga
     5701 caagtaaaaa aatgaaaaag caagggacga ggtatatgga aaaaaagcaa aaaattattt
     5761 taggagccac ttctgcttta actatcgtta ttttaattct aagtttgttt tttgtcatcc
     5821 gatcatctac aaaaaaagaa ccaatcattc ctgaaaaaaa aataacagaa aaagcaaaag
     5881 aaccgacaga tgataagcaa caactagtta ctcaagcaaa aaatctggct caaagctacg
     5941 attatgacca agcgattgcg ttattggaaa aagatagtaa gaacggatct actgaaacac
     6001 aacagcttct tcaaacacta aaaaaggaga aagaacaact gatcgactgg tctgatccta
     6061 ctcagatctc tcatgtcttt ttccacagct tgatcgtgga cccgcaaaaa gccttccact
     6121 ctcaacaggc acaaggatac aaagattata tggtgactgt tgaagaattc aaccgttcga
     6181 tcgaacaact ttatcaaaat gattttgttt tagttaattt gaatgatttg atccaaaaag
     6241 acgaacaagg aaatctttcc tttaacgggc ttgcgctacc tgaaggaaaa aaaccattgg
     6301 ttctttcaca agatgatgtc agctattatg aatatatgga taattccggt tttcctagcc
     6361 gattggtcgt atcaaataac aatgaaatca aaaatgtcta taaagagaaa gataaagaag
     6421 aaatcggtga ctttgacatg gttcctctga tcgatgcctt tgtcaagaaa catcctgatt
     6481 tttcttatcg aggcgcaaaa ggtaccttgg ccctgacagg ttacaacgga gttttaggtt
     6541 atcgaacatc aaaatctcaa tatggagaca atgaaaaaac aaaaaaagag attaaagaag
     6601 ctaaaaaagt ggcggaacag ttgaagaaag acggctggag ctttgcttcc catacatggg
     6661 gtcacttgaa tatgactcaa gcttcactag aagatgtaaa aaaagacaat gaattgtggc
     6721 agcaagaagt tgcacctatc ctaggaaaaa caaatattct gatttatcca tttggtgcag
     6781 acatcagcga ctggcagcct tattcagcag aaaatcaaaa atttgcttac ttgaagagtc
     6841 aaggtttcga tattttctgt aatgtcgatg cttctacacc agcttgggga caattaggta
     6901 cggatttcta tcgaaatgct cggatcaata tcgatggcat tcgttttcaa tctgatttag
     6961 acggaaaaaa tcctattctt gatccattca tcaatgtcca tgatgtctat gacaaagaag
     7021 cacgcgaatc tgcttgattt tacgtcattt atgaaccaaa aaagccgaac tgacatttta
     7081 tcgtcagttt cggctttttt atgctttatt tcttcttcgg tgcgattccc ttgatcagga
     7141 cttctgtcca ttctgctgta tatggaagca gttttgcgta tatctccggc ttagaaattc
     7201 cttctaccat tgcttgaaaa tagaggatca agaactcatc cgaatatttc aaatccactt
     7261 ttccttcttt ccgccctcga tggaaaagat caagcatgat actgaaactt tcttgcgtat
     7321 acgcatccat cgcgtcagaa aattcttttt tttctttttt tgtatagtat gtcatcaaat
     7381 cgatataaaa ttgtttgttc actcgattga gataacggat tttgttttca ctcatggcaa
     7441 tcagtgtttc ttcaaatgga agattttccg caatcaacgc tttcgcttct tgccctaaat
     7501 cattcataaa tgcaaaaaat acttcataaa tcagcccttc cttgctgcca aaatatttaa
     7561 aaatcgtcgc tttacttacc tgagcgttct cagctacctt atccattgtc actccagcgg
     7621 ttcctatgtc tgtgttcatc aagtcaaaag ctgcttgtaa aatctctttc tttttctctt
     7681 gtgctctctt ttcaaaaccg ttcatttgta gagcctcccg taattttaaa cttttataat
     7741 atatatagtt caaatttatt ctgaggttta ttataactat ctattgagaa agtatcaagc
     7801 tagcaattcc ttgtttatga attcattgac agaaatttat aaaaagaata ttatgtacta
     7861 aaataataaa aaaaagtttt ataaaaaggt ataaaacctt tttattaaac tatttaatct
     7921 tgtttagtat atatttttag aaaaaggagt ggggttttta tggcagaaat cgtcaaagtc
     7981 acacatttga aaaagagctt tggtcgtttc gaagctttaa aagatgtctc tttcaccgta
     8041 cattcaggtg aagtcgttgg atttatcgga ccaaatggtt ctggaaaatc cacgacgatt
     8101 cggacacttt tagggattat aaaaaaagac ggcggaacgg caacgatttt tgggcaagat
     8161 gtatgggaag atagtttatc tatccatgaa cgtctttctt atgttccagg cgatatctct
     8221 ttgtggggaa atttgactgg aggagcgatc atcgatctct tcatgaagct tcatggaaaa
     8281 gggagtgctc aaaaaaaaga tgaactgatt caacgtttct ctcttgatcc taagaaaaaa
     8341 gcaaaaaact attcaaaagg aaatcgccaa aaagtgggct tgattgctgc tttggctgtt
     8401 gattcggatc tctatttatt tgatgagcct acttctggtt tagatccttt gatggaaacg
     8461 attttccaag aagaagttga aaaattgaaa gaacagggca aatccatcct actttcttct
     8521 catattctca gtgaagtcga gcgactagcg gataaagtcg tgatcatacg cgaaggaaca
     8581 ctcgatgaag aaggaacact cgatgaattg cgtcatttga ctcgttcgac catcactata
     8641 gaaacagaag cagagaatag tcacttagca caattgaacg gtgtccatga ctttgtgcaa
     8701 aaaggtcacc tcgctcaatt tgctgctgat aacgaagctt tcgatgtgat tttagctgaa
     8761 gcgtccaaat taggtgtgaa aaaatttgaa tctattccac cgactcttga ggatttattc
     8821 atgagacatt atgaaggatg aggaggaagc gaaatgactg ataaattttc acgctggtcc
     8881 accctttttt ctcaaaacct tagccgtgac tggaaaaaga tcctgatatg gctagtcggt
     8941 gtcactgctt tttctggtgg ttttgtccct gcgtttgaag aattgacttc cggacaagga
     9001 ttagctggat tatacgaaac cttgcaaaac ccggcaatga ttgcaatggt cggaccaact
     9061 ccagcttcga atgctgctga gtatacttta ggagcgatgt atgcaaatga aatgttgctt
     9121 ttttgcagtt tgtttgctgc tgtgatctct gttttacacg tggtgagcca aacgagaaaa
     9181 aaagaagaac ttggtctgat tgaacttatt cgttcctttc gagtcggacg tcaagcaaac
     9241 tctttagctg tcatcgctga aagtattctg atcaatttgc ttttagcaat atcgatcagc
     9301 tgtacgatga tttttttcca agcggattcg atcactgcag aaggtgcttg gctttttggg
     9361 ctatctgtag gtagtatggg gattttgggg agtgccgttg cactgtttgc tgcacaactg
     9421 atgccaagtt cagccagttc gaatggtctg tctttagcgt ttttaggtgg actttacctt
     9481 ctacgagcaa taacagatgt agctgattcc tccctttcga tgtggaatcc tttaggctgg
     9541 tcttatttga cctatccatt tacaactaac aactggattc ctttgcttta tttgtttttg
     9601 ttcagtctaa tcttgataat cagttcattt gttttagagg aacatcgaga tttgaacacc
     9661 ggctatatcc ccgaacgtga aggaaaaccg tatgctaaac gttctctttt atccttgcgt
     9721 ggtttattat tctatctaaa taaagggatg acaatcagtt ggcttatcac ttttggtttg
     9781 atgggggcgg catacggctc tatctacggg aatatgcaac agtttttaga aagtaacgac
     9841 ttaatgaaac agatgtttat ccaatctggc gtctcaattg aaaaaaactt tacaagcacg
     9901 atcatggtag tcttgatttg tctagctgct attttaccaa ttgctagcat caatcgttta
     9961 tttacagaag aaacccacgg acgtatgaat cagctgttcg caacaaaaat ttctaggaac
    10021 caactttatt ggaccaatat gttactagct attctatttg ctatattggc aatcctgatt
    10081 agttctggtg cactagggct ttctgctttg gcttcgatga aggatgcgaa agacatggat
    10141 ctattgatgt ttcttaaagc cgggttcaat ttcctgcctg ccgttttagt gtttatcgga
    10201 attagtggct ttctattcgg atggcttcct cgaatcggta aacttgctta tatctactta
    10261 gcttactcct ttgcactcaa ttactttggc ggaattttgg atttaccaga atggttttcc
    10321 aaaacagctg tccctagctg ggttccacgg atgccaaacg attcttttga tctttccgtg
    10381 ttccttacgt tatcatgtat cagccttgca ctgttcgtcc ttggttctat tggttatagg
    10441 cgaagagact tactagaagg ataataaaaa agcatgtaca atttcatgct agcctccaaa
    10501 tctgggtcaa aaatccaaca tttggaggtc atttttttat ttacaagtct tctaactgct
    10561 ctttatcaat gatccagact tctcgattct ttctttttac ataaccattc tcctctaata
    10621 atttaaattt tctagataaa gtttcggggg tcgtaccgat aaatgcagca agttctttca
    10681 ttttcattgg caggaaaaag tgatccttcc ctgtcgcttt agctaagtca agcagataga
    10741 cagcgactcg ttcttctact ttttccatca tcaaaaaagt tgtctgctgc tgtacttttg
    10801 ttaatttctc aacgttgatt gctaaaagtt tcagactaag ggcgggataa tgcagtaaga
    10861 gttccgagaa atctttttgt ctcaatatgc aaatttccgt tttttctagt gcttcgccaa
    10921 ataaagactc atttggaacg cctagcaact ggctctctcc ctcatatccg cccggctcta
    10981 ttactcgtaa aagctgttcc tttccgctag cagataattg atacactttc atactgccgg
    11041 aggccacgat cactaattga ggttctccat tcggcgcaag aatctgttct cctttttcca
    11101 catagtgatg tttgacaagt gcgtgtactt tttcttgatc ttgctgtact aagtgattga
    11161 acaaaggaac aaatgaaaca cataaatgat catgactcat aatctctcct ccttctaaac
    11221 agctatttct aataaagaaa cataacttcc cttattccaa ctgataattt tcttttatca
    11281 tagcataaac gtcaagcgaa ccagatacca gcaaatagag tggatttctt tttgtccctt
    11341 gctttatttt ccttcttttg agaccttaag taattgattc ctatcaattt tttaaatatt
    11401 tactttttga ataatcaaaa acaaaccttc actcgcaagc cgagagtaag gtttgttttt
    11461 cgcattgctt atttcgtgtt gtctattgaa atttttccgc acctagcttt tgatatagtg
    11521 gtgctagttc ttgtaaggtt tcagcggtta tttgctcaac gtgttcgatt tcttgcggat
    11581 agaagaatag tttacccatt tgaaaggttc ggtctctcat cgcttttttc aactcttctt
    11641 gtttctttgt atcggacaaa tagtcagaca aagctaagtg gtcgtcaagt tcatgttctg
    11701 gttgcggcca tatgtaataa tccttgatat cgactgtttt gctccactct ttcagtatcg
    11761 caagcaactg gttatacgct gcaatgctac catatcgttc ttcgctttta taatgttggt
    11821 acatcaaata gatttggtat tgtttttgat tcaacaaaac tgctagacag gcattctcgt
    11881 cttgacgaga ttcgcttcgg tacgcgctcc aaaaatgact gcgtaaattc cagccattcg
    11941 tccagctttc gattttaggt ttgctcatgc cgtacatatc aggcaaaagt gcagctgtct
    12001 ggagctgaat ctctttccat ttttgccagt gttctttata ttctttcttg atttgttcaa
    12061 tcttatctgt tggatggctc tctttgagct gtttgaatgc gtagattggt cgatcaaaca
    12121 actgataatc tgattttcca agttccattg tttcgcctct ttccgttatc ttttgtattc
    12181 tacctgaatt ttgcgatatg gacaaataga ggttgtgaaa aagctgttct gcatcaagtc
    12241 ataagaacag ccaaacaaaa aactgcgatg agcatcaccg cagttttatt gaacttaagg
    12301 ttgattgatc acatctaaaa gcgttgaaaa taaaatggca ctagaagcag ctcctgggtc
    12361 gatatgtccg attgcacgct ctcctagata ggaagctcgt ccttttttag ctaccaagac
    12421 tttggtgtgt tcttttgcct ggtcaatgat ttcttttgtt aaattccctg ccttcaatgc
    12481 ctctgtgact ggcagccaaa catctaacat cgttttatcg tcagcttctg cctttcctcg
    12541 gctttgaata cccgctgttc cctgctcgat cacttcgcct aatttttctt gagaatcaat
    12601 agaatcgacc tcttttgtcg ctttcatcat gttcatgaat gcagatccgt ataacggacc
    12661 agaagcccca ccgactttcg atatcatcgc catagagaat actttgaatg tatcgctgat
    12721 tgtttcagga tgatcggctt gaaaagcttc ttcataagct gaaacccctc ttcccatgtt
    12781 atttccatgg tctccatcgc caatcggggt atctagatca ctgagatatt gtttgttctg
    12841 attgattgcc tctgcaaatt gcgtgagcca ttcttggatt tcttgaacgg ttagtttcat
    12901 attatcaccc ttttatcttg agatttttta ccatgaaatc gtctgtacat tgctttctaa
    12961 agaatctttc cattgtgtct ccgtcaagtc gatcagtgtt agagaaagac cttgcatatc
    13021 tagtgaggtc ataaaattac cgacttttcg gaaaactaca ttgacgcctc tttcttccaa
    13081 cagagctaaa acatcattca tgaacacgaa ctgttccatc aaaggcgtcc cgcccattcc
    13141 gttgactagt acacctgctt cttttggtaa attcgagtaa tcatctaaaa tcttagtaac
    13201 aagttccttt gccagtactt tagaaggctg catcttttct cgacgatagc ctggctcacc
    13261 gtggatacca acaccatact cgatctcatc ttctcctagt tcgaatcctg gtttccctac
    13321 ttctggtaca gttgctgctc gaagcgctag accgatcgtc ttagttgcct gtacgacctt
    13381 ttctcccagt tctttcaact cagctaggga agcaccgttt cttgctgcat cgcccacgat
    13441 tttgtgtaca aggacagtac ctgcaactcc gcgttttcca gcagtatacg tactattttc
    13501 aacggcgata tcatcatcta cgatcacact ttctacttca atatcgtcca tagcagctaa
    13561 ttcctttgcc atatcgaagt tcaatgcatc ccctgtataa ttcttaacga tcagcaaaac
    13621 tccttttcca ctatcggctt ccttaatagc cgtctgaatc tgatctggag ttggagaagt
    13681 aaacacatca ccaagcaccg ctgcacttaa catcccttcc cctacaaacc cggcatggga
    13741 tggttcatgt ccgcttcctc caccagaaac caaaccaact tgttccgctt tctgattctt
    13801 ggctacaaca cgggaagatt ctacacgatg aacaagttct ggatagcttt ttactaatcc
    13861 ttccagcatt tcttcgacaa tattgcttgg atcattcatg atttttttca atttattccc
    13921 atcctttctt tccggcattt tgtgcttctg ttaagatttg ctgagtatca tctgttatac
    13981 cggcagtgat ggctgctgca aaagctcctt ccactaaagg cgcatccacc agatgataac
    14041 gttgctgctg ctcttcttcc aacatgtctt ttgccagttc cgagttcaat accgcgctac
    14101 cgatatccgc aaaaacaaaa taactagctg catcgcttga ttcattgact gcttctacga
    14161 ttttcatcgg gtctgatccg atctcgccat ttattccgcc gagagaaaaa atttgcacct
    14221 cttcggattt ttgcatctgc tcaatcattt ctttaatacc atctgttact ttttgactat
    14281 gagaaataag caaaatactt tttttcacaa gaatcttcct ttcttttaca tagttgctaa
    14341 cgattggttt cgctttcatt aatgaacaat tcaagtatat aataaatttc taattttggg
    14401 aaaatatgtg tagtgcttct tgaagtttgt tatactttaa ttaaaagaga ggagtgatcg
    14461 aatgattaca acaacaacga acagtgtaga gggaaaagcc gtagtagctt ataaagggat
    14521 cgtttttggt gaggtcatta ctgggatcca tgcatttaaa gacttggagg cggggttgcg
    14581 aaatatcttt ggcggccgct caaaaagcta tgaaaacgaa ctaatgggtg caagagaaga
    14641 agcacttgcc gaaatggccg aacgtgcaaa agcattagga gctgatgcga tcattggcgt
    14701 aaaaatggac tatgaagtat taggcagcga caatggcatg ctgatggtca catgtagtgg
    14761 aacagctgtc tccacgagat aagtagggga catctgtttt aataactaaa gagagatggg
    14821 acatgtagtg gcactcaaga attagatttt tcagtctaac ttcgaggtac tctaccttcc
    14881 catcctctct tttttatttc tttttgcgga tgattccgta agctgctgcg actaacacac
    14941 ccgcccctgc taaggaataa ctgacagaag ctgttttttc atttgttttt ggcaaagtct
    15001 gacttgttga tttggatggc tctgtcgttt gctgaactgt ttctgtcgtg cttccagagg
    15061 tcactgattt ttctcctgcc gaatgcaaaa tatcttttat tcgttggaaa ctagctgcta
    15121 agtcagcttt ttttgcttca aaatcattag caactgtttg tgcttcgctg atctttccgt
    15181 ggattgcttg actggccgct gtgatatccg cttgagtttg acttagcttt ccagaagctg
    15241 tttgagcaac ctgatttaat tgctgattga attcttttgc ttgttggatc ttcccgtcaa
    15301 gatctgtttg gacagcttcc gcttttgctt tcgcttcggc aagctttttc tcaagttgtg
    15361 cacggtcatt tcccacttta tttttaagat cagctaaatc ttgatcgatt gctgcttggt
    15421 cttctttcaa tttgtttttt gcagcttcta atgcttcttc gagttctttt cttttatttt
    15481 ccaagtcttg caaatgatcg atttggtcag aagaggtaga actatttatt gatgtatctt
    15541 ctgaagatga aatcgtttct cctgaattat ctgtcggtac attggaagtc atttctgttt
    15601 ccgaggcacc gttttcagca ccagaagagc ttatggttgt tgaaggttct gtttgagcag
    15661 gttcagaagt ttccgcaaaa gctgtctgtc ccaataagaa aatactggaa acagcaattg
    15721 gccagattaa cggcttcatt ctttttttca tcacttttcc catccttact actttttaac
    15781 taatttctta ttataagcaa aaatgtttgg aagaaccata aacacaacag gctgtttgtc
    15841 taaaaaacgg tgcatctttt atttttttgt acgttccggg cttttccatg tcccgcttcc
    15901 ataacctaaa atcgttttga ctgctggaat gaaagtcgtc acgatcgtta tcgcgttcac
    15961 tatccagaac aaaagcatat atagtggtgc gaaaagaagg tatttcaatt ttcttcgtcg
    16021 atcatctaca atcagcgaag ctagcaactg gaaaaatcct gcgaccattt caaagcagat
    16081 gaacacaaaa ctgaatgtaa aagtaatata aatctgttcg tagtttcctt gatatacata
    16141 atgcccgatt aatccagcaa aaagaactac ggaaatacaa aagaatattg accagacaat
    16201 actcaatgtt tgatcaatga agatgatcgt tcttccaata tgtttaaaag gatggagcat
    16261 cacttttttg aaattcgtca gccagacttc tgttccacct tttgcccaac gttttctgtg
    16321 tcgatatagc atcttcaacg tcacaggtac ttccatgaaa aagataatct caggagcaaa
    16381 aacagataac cagtcattta actgatgatc ccaagcaata ctgatgtctt ctgtcgctcg
    16441 atcttgtctg aatccgccca catcgatcaa ggcttctttt cgatacatcg tatttgctcc
    16501 actgtacgca taaagaccac cgaaaacagc tgactgtgtt cgtttaatga tgcccacgat
    16561 acttgagaat tcaaccgttt gagattttgc aatcaatttg gtacgatttt ggacatccat
    16621 atttgcagtg accgcagcaa tatgtcttgc accagggcga atgaaataat tcacatacct
    16681 aatcagtgca tctggctccg gtaccgtgtc tgcatcattg cttaaaatca atttcccttt
    16741 tgcaaaggca agtccgatat taaacgcgtg ggcttttcct ttattttttt cgatccgaac
    16801 cacacgaaga ttagcgtatt ttttcatcag tctagctaat atttctggtg tttggtccgt
    16861 tgaaccatcg tctgtcacta atacctcata gttgtgataa ttcaatttcg tcatcaaata
    16921 ctcgattgta tattcgatca caatttcttc attatgggct ggcaccatga tcgtgatgaa
    16981 cggttcgaca ctcaagggaa catctaccca ttctttttgc ttatgtttgt ataaaaacac
    17041 ataacaccag acaccaataa accatacaaa tccgcctaaa atcggataag aaacgagaaa
    17101 aaaatacata atagacaaac aagtatctaa gaataaatta cctgtatggg tgattgagat
    17161 catttcagtt ccaccccatt ttctttatac aaatctgcaa tgaatgtcgt atctagattt
    17221 ttctcttcgg agacagaata aaaacggacc gtttctctct cttcttttgt tccaaaacgt
    17281 tccgtataca cttcttcaag taattcttgt ctttttttca atttttcatc ttcatattca
    17341 aaagatttat ttactttttt gtatagattt cgattgttcc acctagtcaa tacaaatgag
    17401 gtaatcagga aactgaaaaa aatcaataca aaaaagccga ttaagaaata cagcattttc
    17461 ttttctgata aaaaagcgta caaggaaaaa tccttggctc tttctggtct cgttaatggg
    17521 aaaaagaccc atataaaagg aagaacaacg atcatccatc ctaaaagagc cactaacgtt
    17581 tgccaaatct ttaaccagta attacctttt gaaaaatact tatctttcac caaaattgat
    17641 gcaacttctt ctcttgttac ttttttcata tcctcacctc acgttttttt gttacgacgt
    17701 aggagtttac catacatttc atttcttttc acataaagtg ttcctaaatt tttcctaaga
    17761 aaaagaacaa aacatttctc atcagcaaat gaaaaatatt ttgttctttt tatcagttgt
    17821 tctttttatt ttttatctct taattatgtt gctctttcca atacgacaat gcttttcatt
    17881 cctctagata tcgccgtgta catttgtctg cgtcttcttt gctcatctcc atcgttttca
    17941 aatggatata agattacatg atcaaattcc agtccttttg ctagactcaa aggaatgatt
    18001 tggcagtttt ctaatccata tgaatttttt ttaatcgatt cttgtagcgt ttgggtttcc
    18061 tcttctgttt gggtgataac tgccgctttt tctcctttta gagaaaccaa aatctcagct
    18121 agtattttca acaattcttc agaggatcga aaagagcggt attcgggttc ttttccttgc
    18181 ggtcggatcg atacgatgtc gatcttctct tgatccacag cataggtttt gaaaagctct
    18241 gtgattgctc cgctagaacg gtaactattt ctaagatcat accgatggat cggcagatgg
    18301 tagtcgtcga aacaacgcat aatatcagca aaagtagtgg aagaattaaa gattgcctga
    18361 ttctcgtcac ctactaaagt aaagtgagtt tttggaaata attcgatcaa tagacctaat
    18421 tgtgccaggg tataatcttg tacttcatca atcaatagat agcgaaatgc tggtacattt
    18481 accttttcaa caagtaaatg acgaatagct aatataatga ctgcttcatc aacagtacgt
    18541 gtgggttgcc aagcataagc tgagccatat cgtttttcat aaattctttc aaacaactga
    18601 tgctcatcca cccatgccat ttcttcgatt tgtctggtta tttttcgata ttttttttgt
    18661 aaaagtttcc ttgcataagc tacaatactt tgttccgaat catcagaaat caatttaccg
    18721 aataattcca actgcctatc ttctgtcaac gagagtacct gattctgcac agcaggactt
    18781 tttgcttgtt tcaaaagatg attcttccat tcgctcatca gtgccttttt cgttgcttga
    18841 agcctatcga tcaatttagg atgagcagga actttctcat atattttttc gatcgttttt
    18901 ttagaaagga ctgtttttcc atttttagta agtccacgga taaaattcgg atgatctaaa
    18961 aacaaaggat ctgattgttt tagattatcg ataaactttt tgctacgcaa acgttctgtc
    19021 tgctccgata cattttctcc cgtgatacgt ttgaaataag cctcttcacc ttctatttcc
    19081 tctgctgaaa gctgtgaaac cagctgtatg atggttagat tcagtggatt tctttcacct
    19141 aatgatggta ggacattcga aatatagtcg ataaaccgat gattaggtga tagaatcagc
    19201 aagtcatcgg atgtcatcgt atctcgatat aaatagagca gatacgcaat acgctgcatg
    19261 atagcagagg ttttaccact tcctgctacg ccatttacca agatattttg acttttcaca
    19321 tcccgaatga ttgtgttttg ttccgattgg atcgtagcag tgatagcctt catttcattg
    19381 gtctcatctt ggcctaagac ttctaataat acgtcatctt gaatagctac agacgtatca
    19441 aaaaacttga ccaaacgatc tctttccaaa agaaattgtc gtctttcttt aataaccgta
    19501 tcgattttat tttgacgaac cgtataagaa gatggaccaa tcatgttatt gtaaaaaagt
    19561 tcggcaattg gtgaacgcca atcataaaca agattttcat ctgcatcatc tgtgaaattt
    19621 gctgtaccga tataaaagga ttcttttggc tcattatcca gaaagtctac aacgactttt
    19681 ccaaagtagg gacttttcaa taaacgttcg atctttgcta gctgattttc tgcgtttttc
    19741 tgtttgatat tcatctgatc gatttctcta tttttcattt caatcatcga aaaagtatcc
    19801 aggttatcta agtaactgtc aaaattcaat cgaagctcgc cagccatttc tttcaacgac
    19861 tggtttcctt ctatttttgc cgtatccatc gattcccgca gttcgttttt tttatcaatt
    19921 agcttttgat acacgttctt cagatatgct tcttctaact gtttttgtgt gttgaccata
    19981 cacattctcc tcttttttta aagtggtgga accgattagt ttacctcttt taagagtcga
    20041 atgcaagctt tttaacgagt atcatttgtt aggatatatc agttcttcag gtcggacagt
    20101 ttgatataaa gaaaatgcac catcaaggtt ttttacgtgg tagccagact gcttcaagat
    20161 tctttccgct agatagctac gtaatccgct atgacagctg acgatatatt cttgttggct
    20221 gtctaattca tttaatcggt cccgaagttc attcaaaggg atatgtttgg cttccttgaa
    20281 tttgcccttt tccaattctt ctgctgttcg cacatctaat aaaatttttc cttttgctag
    20341 ttctgtcggc aattcatgcc attgtacggt ttcactaagc ccttctgcaa tgttcattgc
    20401 tgcatatcct agcatgttta ctggatcttt ggctgagcca aatggcggtg catacgtcaa
    20461 ttctaattcc ggtaaatcga agatcgtcaa atgccctttg attgctgttg ctaaaatatc
    20521 gatccgttta tccacacctt ttgccccaac accttgtgca ccataaatct cgccagtctc
    20581 tggatggaag atcaacttca gtaaaatatc tgttgcttct ggataatagc ttgcatgatc
    20641 ttttcctgat acatgaatga cttcaaaaga cagttcgttt tctttggctg ttctttcact
    20701 taaaccggtg gatgcggcag tcattccaaa cgttcgtata attgctgttc caataccgcc
    20761 ttgatttctt cgagaaattc cggaaatcgt gtccgcaact tgtctacctt gacgattggc
    20821 tggtgaagca agagaaataa gtgcatcttt tccagtgatt tgctgtttta caacgatagc
    20881 atcccccacc gcataaatat caggaatatt cgtttgataa cgttcgtcta ctaggatacc
    20941 cccgcgtatg cctaattcga ttccagcggt cactgctagc tggttatcag gacgaacacc
    21001 aatggataaa ataactaaat cagcagggat ggtacgccca tcatccagtc gcaatcgttt
    21061 cccgtggtct tcaaatccag cgacagcatg agaagtaatc acttctactc cttgatgaga
    21121 caattctttt tctataaaag ctgccatttc ttcatccagt gttggaagaa tatgtggtgc
    21181 ttgttcgatc accatgactt ctaaacctct tctttttagg ttttctgcca tttccaatcc
    21241 gatgaatcct gcaccaacga tcacggcacg ctttggctgt ttttctaatg catgcatcac
    21301 tttatcgata tctggtacat ttctaataga aaaaacattg tcggcttctg ttatccctgg
    21361 aatcgatgga acaactggtt ttgcaccagg agataaaacc aatgcatcgt actgttcaat
    21421 gtgtttttga ccctcatgta cgacttctac cgttttgttt tcgggaaaga tggctgtcac
    21481 ttcatgattt ggacgcacat ctaaacaaaa acgagcggat aatgattctg gcgtttggac
    21541 aagaagattt tcccgttcac tgatttctcc cgaaagataa taaggcaagc cgcaatttgc
    21601 aaaagaaaca tacggtcctt tttcaaaaac aacgatttct gcatcttcca ttaatcggcg
    21661 aagccgtgta gcagcagaca ttccacctgc tacacctccg acaataacga ttttcatctt
    21721 atttccctcc tactgttcga tcaaaccatt gattcatgcc accacgtaca ttcactacat
    21781 cataaccaga tttctttaat tctttagctg cttgtttact cctcatccct gattgacaaa
    21841 tcacatagac ggtcttttct ttgtctccat catatctgtt tatactttgt aatggaacat
    21901 ttttagctcc ttttatatgc ccgccccggt attctgcagg tgttctaaca tcaagtaacg
    21961 ctggattttc caaaagcttt tcctttaatt ctgggactgt tatcgatttt attgattgaa
    22021 atagcaaatt cattttctgc acctcattta catttttata aatacctcat ggggtatatt
    22081 aaacaggagc tttattaata tgtcaaccag aatgactctt catttttttc actacttttt
    22141 atatttgcat aaaataccga taaggggtat tatctaatta taaaaataga ggagaatgtg
    22201 ttatggagat tgataataaa aatatcctga accgtttgaa acgtacagag ggacaaattc
    22261 gtggtatcca aaaaatgatc gaagacgaaa aagaatgtat ggatgtcatc actcaattaa
    22321 gcgctgttcg ttctagtatt gatcgcgtaa tgggcatgat cgttgcagat aatctgaaaa
    22381 attgctttga gaaacctgat agtaatccag aagaacaagc ggctaaacta gaacaagcga
    22441 tcaagatgat tattaaaaag taaaggaatg atttcaatga aagtcgtttt ccatattgat
    22501 gaattagaaa aatggtcaga aacagggaaa aacgtaaaaa acctgataaa agcttctcca
    22561 gaaacgacga ttgtcgtatc tgtaaatggc atcgcgatta ccggttatct agactctgcc
    22621 aatgcagaat tcttagattt gcaaggagtc gtttttcacg cttgcgccaa tgctatgcgt
    22681 gctaatcata tttcagaaag ttctttacct gaacaagtaa tcgttgtacc agcaggtgtc
    22741 cttgatttag ttgaactgca atcccaaggt tatgcttata tcaagcctta gtcagtagag
    22801 gttgcgacag aagtgatcag cttcaagaaa tttcggctta tttttcgaag aagctacttc
    22861 tggaaaaccg tgaatcaaag gttgtgaaaa cgctgtcctg catcaagtaa taagaacagc
    22921 caaacaaaaa tagcttctca tatttttcgt ttggttgggc ttattaccgc agatgcaagc
    22981 ttttgaacac cgtttaagga agaggttgtg aaatcagcgg tttgacctaa gtattagaga
    23041 aaaaaacggg aaaatagctc ctcatatttt gccgtttttt gagctaatac cgaaggtcag
    23101 ctgattgaac accgtttaag gaagagattg tgaaaaagtc gcttagtttc gagtattaag
    23161 aaaaattttg tgaaaatgga tttctacatt tttgcataaa tttggcttaa taccgagaaa
    23221 ctggcttttg aataccgttt aaggaagagg ttgtaaaatc agcggtttga cctgagtatt
    23281 agagaaacaa acggaaaaat agctgctcat attttgccgt tttttgagct aataccgaag
    23341 gtcagctgat tgaacaccgt ttaccaagag gttgtgagcc taccatttaa ctccgaatca
    23401 caagaaataa tttcaaaaac aacttctcct gtttttggtt cggttggctt attatcgaga
    23461 agtagctact gggagtctat ttatcaaaaa aaggaatgcg acataggtca cacccctttt
    23521 ttattttctt tgaaacatct ttcggtactc gacagcatac aagacaaaag attgtaaaag
    23581 accgtaagtg atgacggcaa aaatgactct cacccacagc gttggtaatt ctgggaaaag
    23641 cagcaaaagg atcatgccaa catagatgac agcagtcgct actttgccat accacttcgc
    23701 tccacttaat ttgatatttt tagatagccc gattaatcca gctacaaaca taaagccttc
    23761 ttttatcaag aatagaccaa acaacagcca aagccacggt cgataccatg ccatagacaa
    23821 aatcagaaaa agttgtgtca atttatctgc aaacggatca agcaccttcc ctaagtctgt
    23881 tacctgatta tatctccgag caatgacccc gtctagataa tcagacaaac ctgagacaac
    23941 aatgaccgct cctgctatat aaaatgactg tctcagcaca aaataaagat aaatcggcag
    24001 caaaaaaata cggaatatcg ataaaagatt cggaatcgtt tgtatttctt tacgccagtc
    24061 tgtgcttaat ttcattttat cgccctacct cctcagcact cttttctttt tattttagct
    24121 tacacgggga ataaaaccaa tgatttcact gtttttattt ttctttacag acactgatat
    24181 tatgagctaa tttgagataa tcacttgctg ttttcatcgt ttactcttct ttcttcctgt
    24241 cgtttgcgca tttcttttac tagtacttta tgagcttttt ttgatcctcg ctctaggtca
    24301 cgctgccgtt tacgtgtttt ataatcgata aacagactgt ctaaatcgta acctgtcggg
    24361 tacagatctt ctgctgaacg caccagacga acacgctgac gaggcacgtg gattattttt
    24421 ttgtctaaat atacatcaat cgtatcttca cctatatctt cataaactaa cgcttctttt
    24481 tggtattcat tgacaaatat ccgatcacct tttgcaaaga gctgacgttc ttttttattc
    24541 tccttcctat ttgtaactgc tgtcttagga agaaattctt ttttctgtgt ccgataggct
    24601 ttttccgcca agtaacgctc tgcttgatgg atcaatttca tcgacatatc cattttatga
    24661 gcaatccaca aagcttggct ttctcctgtt tcttccaacc cgcaactgat atttaggacg
    24721 aagtgcttcc cgatcgaaag ccatagcagc cggcacaaaa tcttcatgat ctccggcgaa
    24781 tttcttgatt tctccataat gggtcgtggc aatgatcaat gccccttgct catacataga
    24841 ttccatgatt gcgatcgcta gtgcagcccc ttcatttggc tctgttccac tgccaatctc
    24901 atctaaaagt accaacgtat tcctttttat ctttttcaaa atagcagcga tgttttgcat
    24961 atgaccagaa aatgtactca acgcattttc taaattttgg tggtcaccga catcgacgaa
    25021 aatctcatca aagacagcaa gctctgtccc ttcttttgcc ggaacttgca taccgaacat
    25081 cgccatcaaa gtcaataaac cgactgtctt caacacgact gttttgcctc cggcatttgc
    25141 tccggtgata atcaagcctc gatagtcttt accgatttca acatccaatg gtaccgcatg
    25201 ctcaggtaaa aatggatgtc tgccttgctt gataatgata tgttccgatt tattgattct
    25261 aggtgtgctt ccattgattt ctcggctaaa ttttgcccga gcaaagatga tatctaacac
    25321 cgtgatcgtt tcgatcaata aatcgatcac ttcttcgttt tctgcgatag caccagtcaa
    25381 tgccgccagg acttgatatt cttcactgat ttcttcagct tttaacaact gatagtgttc
    25441 attcaattta gaaatcacag ttggttcaat aaaaaccgtc gttcttttat ttgattcatc
    25501 gataatcgtt ccatctattt tatttttata gctggctttg ataggaatcg tatagtattc
    25561 gcctttttga acaatcattg cttcttggat catttctttg tttttcggat gacgcaagaa
    25621 tttcagtaat tttgactgga tttctttttc gattagttgt aattgtttgc gtactttacg
    25681 caaattacgt gacgcgtcgt cactgacttt attatttttt attttctggt caatcaactc
    25741 ttctacattt atcaaatcag gaagatgttt gctataagca aacaacaagg gtgtctggta
    25801 ttgattctta tcaaaaaact ttgtgatcat ccgactgctt ctaagaaaat ccgcatattc
    25861 gatcaaatcg gttggctgca gaatcaaccc ttttttgact tgttctgtca gtgcatcgat
    25921 cctcggcaac cccataaatg gaacatgctg actgctttct aagatcaagc gtgcttctct
    25981 tgtttcttct tgacgatcca agacagtttg taggtttgtc gagaccgtca tatcgctgat
    26041 tcgttttttg ctatagtttc caattgctct tgcttggatt tcctttttga tccgatcaaa
    26101 ttgtaattga ctaatcattt cgttgtccat attctctcct tttcttgaag agatacctgt
    26161 cccaaaataa ataagggcct agagataaat aaaaggatag aacacagctt aaaaaagtca
    26221 tgtcctatcc ttattagaat acaaagatat tgttttcctg acaggtaccg tttcataagc
    26281 acaccaaata aactttgttt attggctatt cgacttactg attagatacc agctacactc
    26341 acaaaacata ccccattctt ctaggtctta tttattttcc acttaactat agcaagacac
    26401 attttggttg tcaaacttta gtatgtttta tagatttaca ccattaatga atagacacct
    26461 accgcgataa ttgctccgat cattggacct gcgattggta cccatgaata tgcccaatct
    26521 gaagttcctt tattagctat tggcaatacc gcatgtgcta atcgaggacc aaagtcccga
    26581 gcagggttga ttgcatatcc tgttggccct cctaatgaaa gaccgatggc taagatcaat
    26641 ccacctacag cgaatacgtt cgttccaggt gcaaattcgt tttgtccaaa agctagcaac
    26701 ccaagaacta atacaaatgt accaattaat tctgtgatca catttgctgg ataattccgt
    26761 atagcaggac ctgttgcaaa cgttcctaaa atcgcgcttt catctttcgt tgcattccaa
    26821 tgtggcaaat aagaaagcca aacaagaatg gcccctgcaa aagctcctaa aacttgcgca
    26881 atgatgaaag gaacgacaag attccaacta attgcccctg tcatcgccat agctagagag
    26941 actgcaggat tcaaatgagc tgggcccatg aatccagaaa tatagacagc cattgttaca
    27001 gcgagtcccc aaccaaatgc gatgacaatc cagccagaag cctgtgcttt acttttgttt
    27061 aaattcacag ccgcacacac accatctcca agcaaaacta ggatcagtgt cccaataaac
    27121 tcccccatga tttgagtcat atcactgttc atttatttct ccccctttag ttcccgcaga
    27181 tctgattctg caatcaatgc ttctaaacgt ttagtctgtt gcgccttctc ctcttctgtc
    27241 cattcaaaat atccagcaat tgcatcgatc acaggttgct tgatctcatc aagctgatct
    27301 cgttcaaaca acagatgatt tgtacgacga atgagataat cgcctggggc caaaaccatt
    27361 tcttcttcta aaccataacg taaccgagct gactcagcga gactcaaacc aggataaggt
    27421 gccatttctt ttgctaattc aaagatacgt cgggcattag tcccgtaaaa atcagcgata
    27481 taagtagcat cttcttcctc taaaccggct gctactcctt cttttgctaa ttctgtcact
    27541 gtttcttcta atttagttgg atcgaagttt ccacctgaaa tctgatattt tttagagtcg
    27601 atttctttcg tctctattcc gtattcttct tttaataatt ggcgtatcaa tcgcaaagct
    27661 ccttctgcca tcttacggta atcggtgatt ttcccaccag ataaagtcag caaaccatct
    27721 ggttctcttt ctaaagaact acctctggaa atcgtagaag gtgctttttc atcacggctg
    27781 ttttccaaat ggttcaacac gtcttctact tcagcacgag aaactttgtt ttccttatat
    27841 tcacttactg tatcgacaac tttattgaag ctcttgtctg aaatcgatcc attatctcca
    27901 ccattgtaat cagaaccaga attaccaatc aacagtggac gaagtcctgc ccagcttgct
    27961 tcgatatcat tcaatgtgat atttgcttct ggatagcgat gattgatcac atccaataga
    28021 taatctacat cttcttgtgt gactttcgga tccgtaaaat ctccttggta atccgtatct
    28081 gtcgtaccaa agtaagtctt gttttctctt ggaatagcaa aaaccatccg cccatcttgc
    28141 tttcctgtat cgaagtatgt gggttgcggt acaggcagtt ttttcgcatc tacaactaaa
    28201 tggatccctt tagttggacg cattttagga gagactggac gcgtaaaatt caagtttcgt
    28261 actttatcta cccaaggacc actcgtattg atcactaatt ttgctttgat ttcgatcact
    28321 tcatctgtca gcaggtcacg agctttgacg ccaacgattt gatcgccatc atataaaaag
    28381 ccaaccgctt tcattttact tactagataa gccccatctt cggcagcctt tttgatatta
    28441 tcaatcacta aacgggcatc attgttgcgg aaatctagat agacacccgc gccttttagc
    28501 ccttcttttt tcaaaaacgg ttctctttcc aatacttctt ctggtgtcag cgtataattc
    28561 tcatatttgg ttcctgtcac atttgccagt ttgtcataaa ggtccattgc tactttgacc
    28621 gagaacatat tgaaggttgt tgctccttcg ccctcataga ttggcaaaag cattggatct
    28681 ggttttggga tgtgtggggc aatactttgt acgactgcac gttcaccaac tgtgtcagct
    28741 actacttcca catcaaatgt cttcagataa cgaataccgc catgaacaag tttggtcgag
    28801 cgagaggaag tcccttctgc aaaatcctgc atttcgatca atcctgtttt gattcctgat
    28861 gctgctgact ggactgccac accggcacca gtgattccgc caccgatgat caacagatcc
    28921 aattcttctt gctgcatttt ttgaatgcta tcttgtcttg tcttgtttga aaacatatgg
    28981 atttcctcct tattcaaatg cttgggtagc ttttactgct tttttccaac cgttgtaaag
    29041 tttttctcgg cgctcttcct ccatttgaac ttcaaatagc ttgccagctt cataaaattc
    29101 gcggatctcg tctgtatctt tccaataacc gacagctaat cctgctaaaa atgctgcccc
    29161 tagcgccgtt gtttccaagt tttctgctcg ttggatcggt acattcaaga tatctgtttg
    29221 gaattgcatc agatattcat tgtttgctgc accgccatct actttcaata caggaatctt
    29281 gattccagtg tcatcttgca tcgtatcgat gatatctctc acttgataag caatcgactg
    29341 taaagtagct ttaatgatat cttcttttgt cgtaccacgt gtcaagccaa acatagcccc
    29401 tcgtgctgcc tgatcccaat aaggagcacc tagcccaacg aatgcaggaa caacataaac
    29461 ctcatcttcg cttgtagagc gtttcgctgc gtcttctgaa tcgctagctt tttgcaacat
    29521 ttgaagtcca tctctcagcc attgaatcga agaaccagcc acaaaaatac ttccttctaa
    29581 agcatagtaa acctttccat ttatgccgta accaattgtc gtcaataaat tatttttgga
    29641 taattgcggt ttttcaccgg tattcatgac aataaatgaa cctgtaccat aagtattctt
    29701 gaccatgcct ggttcgaatg ccatttgtcc gaataatgcg gcttgctggt ctcctgccat
    29761 ccctgaaatt ggtgcttcgc ttccataaaa atgataacct tgcgtataac cataaacttc
    29821 tgagttagaa gtgacttttg gtaacatcac tcgaggaata tttagtaaat ctaaaatctc
    29881 ctgatcccaa tctagctgat ggatattgaa caacatcgtc cgactggcat tcgagtaatc
    29941 agtaacatgt gcttgtccat cggtcagttt ccatactaac caagaatcga tcgttccaaa
    30001 catcaattcg cctttttcag ctcgttcttg cgcgccttct acatgatcaa gaatccagcg
    30061 tatcttcgtt gctgagaaat aggcatcgat cactaaccct gttttttcgt ggaaaaattc
    30121 ttgatagcct tcatttttta agttatctgc aattccagct gactgtctgg attgccaaac
    30181 aactgcatga tagattggac gtcctgtatc tttttcccat attactgttg tttcacgctg
    30241 gttcgttatg ccaatcccag caatctgatt tggtttgatc cctgattcga tgaacgctcc
    30301 ggcaataact gactgtacag aattccagat ttcatttgca tcatgttcca cccaactttc
    30361 ttgcgggaaa tattgcgtga actctttttg agaactgccg atgtgtcttc ctttcttgtc
    30421 aaagataatt gctcgtgagc tagttgtacc ttggtcaatc gccatgatat acgttgattc
    30481 tgtcattgtg attccctcca ttatatgcaa acgctttctt taactactct tatcatacta
    30541 ctgttttaaa aaaagaaact gtcaaaattt tattcttttt ttcttttttt gacagttttt
    30601 tattatgaag ctatttttta atcaattctt ttcttttttc agcgtctcta ttcttctttt
    30661 caatcgaata atgtcgtaag gtgacgcaaa ttctgacaga taatattcac actgtttttt
    30721 gtttctctgg caaaatgtga tcaccaaatc atattcttta ccttcttcat aacttccaat
    30781 ctcaataccg ccgattcccc tcagttctct gatcagatat tgttgaaaag caatacgata
    30841 aatcggcaga ctttctaaat cgattccaat cactactggt tttgcaatat aaaaatcgat
    30901 catcaaaaga acattggcat actggatcat caggtaacta agctcactat cttcagctct
    30961 tttcctcggc aattgctgca ccgctgtttc ctgtaatttc gccagtaact gtgttaagga
    31021 atgcccgagc attttctgct gctgttccaa aagccgatca cgctcataga cttcgatctt
    31081 tccaacaaag aaaaaccatt cattgttgat ctgggaaatt tggtagccta ctgccttttc
    31141 ttctttgatt ttcaaacgac gaggacgata atgccataac atcgtttccc gaatgtaagt
    31201 atctaaaaca gcggttggta actttttgct ccgtgtcaaa tcatactgat aaaatatttc
    31261 ttcgtctact atcgaaaaag aaacaaaaaa gctgtaaaac atcattgttt cgtatacatt
    31321 cagttctgct gctgttcgac taagatgcat cacgatgatt ggatcgattg cttgataaag
    31381 ccggtccgac tgatagagta atttcttttc tttcaaagtt gcgtacgtac ttttttcatt
    31441 caatagtctt tttttcgtaa tcccgagcca gcaagcaatc tgtgcttctg ctgatgccgt
    31501 aaacgttgtt tctaatacac ggtccaatcc tagaatgaac ggtctttttt ctggtgtatt
    31561 ttgcaaaaaa agcggtcgct gatcttccgg gatatattgg aatagttcat aataaaaata
    31621 tcgtatctgt agctcttctc cgtataattg accgtttttg atttgtaatc caaattcctc
    31681 taagagctgg ttcaattctt tgatctttcg aaaaacagaa gactcactga tattaaacgc
    31741 tgtcgctaat cgaacgatgg atacttgctg atgttctaat aaatagacga gcatcttaaa
    31801 cttcaagctt tcctgcaata aaaacaatag aattttttcc aaacttacat cttcgtccaa
    31861 cacaagcagc gcctgatact catttcgctg tacttctact tttttttcca tcattcggcc
    31921 aatcaattca atatcttcca aatattgatc aaacgaggct tttgacagtt ggacatgctc
    31981 tctcaaacca ttgatagagg ctgttccccc ttgcagaaca aggtttcgca aaatcaggat
    32041 ctgtaactgc tcttttcttt ctaataatgc ttcaatcttc ataggcagta ttcgccacct
    32101 ttgaccacac catatctggc acacggtatt ctggctggaa aaatagctca tgttcttcta
    32161 actgttcaaa cgtccatcct tcttctactg caattgtcag ttggtcaaga aggtggaaca
    32221 tctctttttt gctttggagc tgtgctccaa gaatcttttt ttcagaatca aatagaaatt
    32281 tgagtttaac tttgctttga tttattgctg taagcttgta gtctacgtat cctgtttcaa
    32341 ttttttgggg ataaaaaatg ctctcttctt ctgtcaaacc tacgcttcct aagaaatagc
    32401 caaaccactg attgccgact ggacgatagg ttccctgatc ctttgtctgt gagccactaa
    32461 ttgtcttgct gacatttcgt gctgtacgga cagcgttatt tactagagaa acatacattt
    32521 tttcatttgt tggacgaaaa gttacttgga tcgcatcgcc aatcgcataa acgtcttttt
    32581 gagacgtttg caagtagtca tctacccaga tcgttccatc atcattcaat gttaattgtt
    32641 cttcccacat ctgattgtcg ggacgagaat gattagccag caaaacaaga tcatagttct
    32701 cctttctttt ttccgtctct acaatagcgg tttcattttc ggtcaaagac acaacttgtt
    32761 cttctaaaaa aagtgaaagc ccttgatttt tcatttcctt tactaacggt tctgtcattt
    32821 caggatctag ataacgaaaa agaattgact ttcggctttc gtaaagatgg atttgttttt
    32881 ttcttgatgc caacccttca gctatttcga ttcctgcttg tcctgcacca ataattgcaa
    32941 ttttctttgc attcatgatc ttttgctgaa gagccgttac gttttgtatc tttttaactg
    33001 ggtgaataag cgttgattct gcagaaatat ttcgaaactt ttgatttgaa ccagtcgcta
    33061 gaatcaaacg atcaaaatcc aatttttttc ctcctgctaa aacgactttt ttttctttca
    33121 atcctattac tgtcttttct gtgtaaacat ggattcgata gcggtcagtc agttcttctt
    33181 tcgtgatcca agaaagttgt ttttcactgg taacctttcc ttttaatatc aaattgaacc
    33241 cgctgggaat ccatcctaac ttcgattgct tttcaatcaa atatatttca cttgttggca
    33301 tcaattggcg aagataaata gccgcatgaa tccctgcaaa cgacccgccg acaattacaa
    33361 tgttcatctg cattcctctt tcttataagg tgttctactg ctaacttctc aatcagaaaa
    33421 cacagtattc ataactcgct ttcaacctta tgatacatag cgatgcagca gaatcaaccc
    33481 tctccatcat accgtgttct aggtctgctt ctcaataatg tactagtgga cctaattgaa
    33541 gagtatcatt tctgaagaga tgtttcaaaa aatgtactct tataaaagaa aaaaactcgc
    33601 cttttacgta cctctgtcca aataggaaac agaaaagaac gaaaagacga gttttagcgt
    33661 gtgtaatgta atagttagaa tagacacatc atttattttt aattctttaa tgcttcaaca
    33721 actgcttcgc ctaattgatg agcagattga ggattttgcc ctgtaagaag ccgcccatca
    33781 atttgaacca cttctgaaaa agctgctcca gactgatagt ttgctccttt ttctttcaaa
    33841 gcatcttctg ctaagaatgg tacttcattc gttgtaccat ttgcttcctc ttcttcatta
    33901 ctgaacccag tcactgtacg tccagctaaa atagattttc cagactcatc tgtaactggc
    33961 aacaatccta caacaccgtg acaaacagct gagaccagcc cttcatttcg atagatttgt
    34021 gaagcgactt tcccaagatc tattgcttct ggaaaatccc acattgttcc gtggccacca
    34081 gcataataaa ccgctgcata atcatttgca tccacatcat caggacgtaa ggtatttccc
    34141 aaggcccgat ttctgaaatc ttcatcttca taataggccc aatcgatttc atccatattc
    34201 aaaacacttt gcggttctaa aggtacatat ccgcctttag gactgacaaa atctgcatcg
    34261 atcccatttt ttactaatac atcataaaaa tgagtcagtt cacttaacca caaacctgta
    34321 ggacgctcga tcttttcgta cttttctaca tttgttaata cgatcaatac tttcattttc
    34381 ccatcctctt tctataaaaa ttgcgttatt gataacgtgc tttcaagaaa ttatataatg
    34441 ggcttggcaa ataaagctct ttatatgctt cttcaaaagg tttcgttaca aattcatcct
    34501 cacggttttc caataatttc tctgcccagt caggatcgac gatcatttgc tgtccaattg
    34561 ctgcaagttc tgcatatttc aatacctgct ctacatcttc gcgattgcgg atcccaccga
    34621 caccaactaa agggatcttt ccttgaatcg tgttatggac cacttcaaga atcgatttat
    34681 cgttgtattt atcagaacga gctattcgat catacatatt taatgaaaca tgcagataat
    34741 ctagttttga ctcacgtaat cgttcaagaa gccagatcgt gtcttcaaaa cggatacctg
    34801 gtgtttcata ttcttctggt gagaaacgat accctacgat gaatggtttt ttagcatatt
    34861 gttcaaccgc tgagaaaacc gttgttaata attcttcaat aaaacgataa cgattttcca
    34921 agctaccgcc ccattgatcc tctcgtctat tcgaatgcgg agagaaaaat tgttggatca
    34981 aatacgtatt tgctccatgc aactcgattc catcaaatcc tgattcaatc gctctacgtg
    35041 tggctttgcc aaatgcttgg attgtttcaa cgatttcttc ttcactcatt gctcgtggtg
    35101 tttccgcatc aggacgtttt gctgcaactg cacttgcaga tacaggctgt tctccagata
    35161 aagttgctcg acttgtcatt cgtccaccgt ggaaaatctg aataatcgct tttgcgcctt
    35221 ctccttggat tgctttcgct agctcactta atcgaggaat catttcatca tgagcgatgc
    35281 tgagttcacc tggccagcct tttccgatat cttggacatt tgcagcacca gtaataacag
    35341 caccaagacc tttagaacgt tgtttataat aagtgatctc atcttcggtg atcactccat
    35401 tgaaaaagct gagttgtgtc gtcataggcg acagcatcaa tcggttcttc aattgaactc
    35461 ctgaaggtaa agtaattgat tgatcaaatt gtgacattgt cattcctccc ataattcgct
    35521 ctgattaacc tatcgagaat catctatcat taaaccactc gattagttgt acatgcaact
    35581 aatttgctta aaaaatttta ttttttttgt aacttatctg ttgcatcatt cattgtctgg
    35641 gctaattctt tacttgcttc atttcccaaa actgctttgt atgactgatg aagttcttcc
    35701 cagctaccat cgacttcctt agcaaattgg cgtccttgtt ctgtaagata aactaatgac
    35761 aagcgacctt cgctaactgt tttgacgtat cctttatatt ctaatttttc aacaaaacga
    35821 gcaatcgttg atggggcgga atagagcatt tgtgcaatat ctttttgtgg tattccatct
    35881 ttttctttta atatcaataa aataaaacca taagttggtg ccagacctgt ccttctaaac
    35941 gcttcatcag ctaatttatt caacatgcga tctagctttt tcacgctaaa gaaaagacat
    36001 tcatctaacg ctttttcaat tggcttttcc atttcatccc ctccattggc gtacatatca
    36061 tagtatgatt tttatttttt gtcaaaaaac acggaataat gtccgcctcc tctgtctaga
    36121 tttgaaaaaa agaagtagcc atcttcaaag aatttcggct tgttttcgac aaaactcctt
    36181 ctggaacacc gtgaatcaga ggttgtgaaa aagtcgttta gttttgagta tgaagaaaaa
    36241 ttttgtgaaa atggctttcc acatttttgc ataaatttgg cttaataccg aaaaactggc
    36301 ttttgaacac cgtttatatc agaggttgtg aaaaagccgt cctgcatcaa gtaataagaa
    36361 cagccaaaca aaaatagttc ctcatatttt gtcgtttttt gagctaatgc cgatggtcag
    36421 ctgattgtac accgtttatt gagaggtcgt gagcctgccg ttgaactccg agtcacaagg
    36481 agcaatttca aaaaacagct tctcatgttt tatgactatg gtgacttgtg atcgaggagt
    36541 tggcaggaga atactgttta ttcgtaaaga aggggctgtg acaagacttt tgtcacagtc
    36601 ccttatttcc ttttattata ggatttcgcc atttgattgg atgacttgtc tgtaccaatc
    36661 aaatgatttt ttctttaacc gtttctttgt gccattccct tcgtcatctt gatcaacata
    36721 gatatatcca taacgttttg acatttgtga agtagaagcg ctgacgatat caatgcagcc
    36781 ccacgacgta taaccaaata aatctactcc atctttgata gcttccttca tctgctcaat
    36841 atgctgcttc aaatagtcaa tgcggtaatc gtcttgaacg gttccatctt cttctacttt
    36901 gtctatagct ccgagtccgt tttcagctat gaacagtggt ttttgatacc tatcatataa
    36961 ttgattcaaa gcaattctca aacccttagg atcaatctgc cagccccatt cacttgatgg
    37021 aagatacgga tttttaattc ctccagttat taagtttcct tggacccctt cccaattttc
    37081 tggatgagca ctgactgcac tagacatgta gtagctaaaa gaaacaaaat caacagggta
    37141 ggctgctaag atttcttcat cacctacttc tatttttaag ttgacacctt tttcttcaaa
    37201 cattcgttgc gtatacgctg gataatatcc tcttgcttga acatcactaa agaacaaaga
    37261 agttctttgc tgctcaattg ttttttgaat atcatccgga tcacaagaat acggaacaag
    37321 aagctgatag ctgatcatac aaccgacttg tgaacctttg ataatttcat gacaagcttt
    37381 tgtagctaaa gcacttgcta taaactgatg gtgtgcacct tggtatttcg cttgttccaa
    37441 atggggatgg ttttcttcaa ttactcctac gctaacaaaa gggtgatgtt ttacacagtt
    37501 gatctcattg aaagtcatcc aatattttac tttattttta tagcgtttga atactgtttc
    37561 agcgaaacga acgtaaaact gaataagctt tcgattaggc catccaccat attctgtaac
    37621 caaatataac ggcatttcat aatgggaaag agaaacgact ggctcaatcc catattttag
    37681 acattcgtca aacacttgat cataaaaaaa taatcccgct tcattgggtg tttcttcatc
    37741 accatgagga aaaattcttg tccatgcgat agacatccga tagcatttaa aacccatttc
    37801 agcaaataaa cggatgtctt ctttaaagtg atgatagaaa tcatttccgt gtcttttagg
    37861 ataataatac ttgctgttgg gatcctgcgc cgcttttact tgctgatgcg tcatcatatg
    37921 ccattgatct gtccattttt ctttaggtaa atcgctgtcg aatgtataca catcagacac
    37981 agataatcct ttttcatcta catcccatgc accttcacat tgattggccg ctgtcgctcc
    38041 gccccataaa aatccttctg gaaatttttt catatcgatc cccctaaact tgctagtttt
    38101 cttgtttgat tatttttctt atgactagta atgatatttt tgaatctact actatttgta
    38161 acaataacca ttgtggtcgg atcatatccc tctttgatta attcttgcaa atctacttcc
    38221 atcaataaat cgcctttacg tacttttttt ccatcagata ctgcactttg aaagtatttg
    38281 ccatttaaat tcactgtatc aataccgata tggatcagta tctctgctcc ttcttcactg
    38341 actaccccaa ttgcatgttt cgttggaaaa actgttgaaa cttccccgtt tacagaactg
    38401 tagatttttc cgtccgttgg aatgatcgca aacccttctc ctaaagatcc actagcaaat
    38461 gttggatcgt ttacttcaga taaatcaatt atttcacctg ctgcaggagt acttaacact
    38521 atatcctttg aggattcttc ttcgatttca tccttgtagc cgaaaagaaa agttagcata
    38581 caggaactga tcatcgctaa gaaataacta gcaactagcc aaacaaatcc ttcaccaata
    38641 taaatcggga aagacaaaat acttcttgta gcaactgcca aagcaccggc tcctgcggca
    38701 ccagctactc caccaaatat agctccacat atacaagcaa tgtaaaatgg tcgtttatat
    38761 ttaagagtca caccataaac agcaggttca gtgattccaa ataatgctgt gataaatgca
    38821 gataaagata aactttttac tttcttattt ttcgttttca aaaatacccc aagtactgct
    38881 cctgcttgcg cagctacggc agtcatacat gctggaccta gcgtatcacg accgtagaaa
    38941 gaaagattgt tggtcattac tggtacaagt ccccaatgta acccaaaaat cactaacact
    39001 tgccaaaatc cgccgataac agcaccagat aaaacagggc taaagttata aacagctaaa
    39061 tatccagctg caatcagctg acttgcataa tctgcaattg gacctacaac taataaaata
    39121 attgggacca tcacgatgat acaaatgaat ggtgtcaata aatttcgaat actttcgtgc
    39181 aagcttttgc gaatcttagg ctcaatataa gaaagaaccc atacagctaa aattgctgga
    39241 ataaccgtac ttgtatacct tgctagaatc acgggcatcc ctagaaatcg caaggttatg
    39301 ctatcactat atgcactgac aatcgtagga taaacgagag ctgctgcaat aaccatagcg
    39361 atgaaacgat ctgtattgaa cttttttgca gcagtatatg ccaaaaatat aggcaagaaa
    39421 tagaaaaatg catcagctgc tgcattcaaa atgatataag ttcctgattc agtagttaat
    39481 aaattcaaac tcgtacataa ggcgagtact cctttgatca aaccacttcc tgccaagacg
    39541 cctaaagtcg gggcaaaaac agcggcgatc atgtctataa aagagtttaa aatgcctttt
    39601 ttctcagttc ctctctttcc actagatgca tcatcttcta gtttcatttg tttggataat
    39661 acgtcataca cttcatttac tgcatttcct actacgactt gaaacattcc tccagcttcg
    39721 actacagtga tcacaccttc tagttgctct accttctcct tatctgcctt cttattatct
    39781 tttagggtaa agcgtaacct tgttgcacaa tggtaaacat tgctgacatt ttcttcgcct
    39841 ccgacaaatc ggacaatatc tttcgctaat tgtgaatagt ccatttttac ttcccccttg
    39901 ttaattaatg ccgtagcaat ccttcttaca agataagtat agttcttaga aaacggtttc
    39961 tccattcaat tagtacccct tctaatagcg aacgaaactg tacaatagtg tgtatggttt
    40021 acttagccga gcaaatcact cactgcttga aagaaaacaa gtatatcgtt tctcttatag
    40081 tcaaaggaga caaaaaaaac acgcttgatc ttcctttgct gatgtataag tggtatctca
    40141 agctgatact ctgtgatttt tgtttctact tggcttttga taagacagca caacaaagtc
    40201 tcggcattta acggaagcat aactaggtca gaactaggag agattagttg ctgaatggaa
    40261 tctatctttt tatggatttt tatttgattt tcttctttgt agtaatgatc aagcagtttt
    40321 gttttctttt tttcttcaac tatggtcagc ttttcacgca aaatctgata aatctcccaa
    40381 gattcaaact catctagaac actaggtaga taaatcaaat catcccactc aaaaataagc
    40441 tcttgctcag tagtcaaaat tgcatcatat tccgttattt tgtttgattg atttttgaaa
    40501 agatacactg gttctatccg gcattctttg atccacatgt tcatactttg ttgaatctgt
    40561 ttttttagtg tattcaaaat actaattggc tggttactaa caatcagtat ctccccttgt
    40621 tttcgaaaag gattcaacgc ttcggcaaga tacaaaacaa aataagcgct ttcagctaaa
    40681 ttgggacgta attgaaaatg tattgggaag aaacgccgaa ttaaataaat ttctaaagga
    40741 taacgggaga tgatcttttg tacaaaatga ttcatggtat tatgtccggc atccatcctc
    40801 gttttcattt gtttgatatg ggttagcaaa aattctgttt catggaacaa taacgaaaca
    40861 ggaagatcta aaaaacgaat aatcgtttgc tcaaatgctc ttagattctt ctctatttct
    40921 ttgttttttt catcattaat catcaaataa tttaactcta atagtcgatt ttcaattgct
    40981 tgtttttctt gattggaaaa agaatagggt agttctgatg ataacttttt tgtgagggtc
    41041 tctaccatcg gaataaataa tgtatacctg tttgtttttt ctaaaagttc ttctcttcga
    41101 agaatggtca aaacgagata ccgagaaaat cgtatgaagt cctctcctga aacaatataa
    41161 ttatatgata taagaacctc ttttaatgtc ttttggacag tcggcatgat attggaaaaa
    41221 attgtactga tttgttgagg aaaccttgcg tgttggatca ccgtttctgt tccaacaaga
    41281 gataagaaaa ttctttttga attttcttca gcaatgattt ttagtccttt tgtcgacgaa
    41341 acttccagtt ctaatttagg attgcgctcg atccaacgca aaatcgtttt tatttgtaat
    41401 gatacggctg tttttgaaag aaagaaaatg tctgctatct tttgcatact gacataccct
    41461 ttttgaaaca ataagtacgt cacaatagtt gaagctcgga aatccatgct ggaatagatt
    41521 ttatgtttcg tcacctcttg tatgatttgc tgtttagttt cagattcaat tgattctaaa
    41581 aaataacctg aacgtttatt tgactggata atgattttct tctcgtagat agcaagcata
    41641 tttttgattt cagtttggat cgttttcttg ttggtaccta aagcttcagc taattcttcg
    41701 cttgttatcc aatgattctt atttcttaat actacaagaa tttggagttg tcgtttattt
    41761 aagtccattt gcttacacct cctctttgtt ataaacatac aggaaaaacc tctcaaatga
    41821 caatagtcac ttgcagaggt ttaaaaatca tttgaagaaa gatctatatt caaggttttt
    41881 accattagac tggataattt gtttataata ttcaaaacta tcttttttca atctcctaaa
    41941 gcttccgctc ccatcatttt gtctatccac ataaataaag ccatatcgct tcctcatttc
    42001 ccctgttcct gccgatacga tatcgattgg tccccaccat aagtaaccaa tgatttggca
    42061 accatctttt attgcctcag caatttcctg aagatgtatt tttagatact cacaacgttt
    42121 tggatcgtgg attcgattca attcatctgg tgcttcatct agtccaatgc cattttcaac
    42181 tatgaataat ggtaattcat aacggtctgt caattcattc atgacataac gaaaccctag
    42241 aggatcaatt ggccaactcc aaggttcggg agatttttcc ttcaaaaagg gattatcgaa
    42301 accatttgct ccgccagtat ctacgcgcat ttctgcttct tttttataga cagcgctacg
    42361 ataataacta aatgcaatat aatctgccgt gttagcttgc aagcactgtt cgtctccatc
    42421 taacattact ggtgcacagt cttcttcctt ccatgtcctg taaatataag ctggataatg
    42481 ccctcggcac atgacatcgg agaaaaacca tgaattgcgt ttaaattgca gtgaaccaaa
    42541 tacattctct ggatcacagt catatgcata agtcgctaat gcagaaaagc tacacataat
    42601 acccatctta gcatttggat cgattttctt taataattga gtagcacggg cgttcgctag
    42661 aaacatatga tgacaggctt gataaatcac tttttttgtt agtgtagcaa tgggttcaag
    42721 tttatctcta gcagggaatg taaccaatcc agcagctgca taaggcatac gaaaagcatt
    42781 attgatctca ttaaaggtca tccaatattt cactttccct tggtagcgtt caaagacggt
    42841 ctgcgcataa aattcaaaaa agtcgattaa ttttcgattt tgccaccccc catactctcc
    42901 taccaatgct aagggggttt cataatgact aagagtaatt actggctcga tatcatatcg
    42961 atttaatgta ttgattagtc tgtcataaaa tacgagacca gcctcatttg gcttctgttc
    43021 gtctcctctt ggaaatattc gtgcccatga gatgcttgtt cgaaaagctt ttaaacctaa
    43081 ctccttcagt aaacgaatat cctcttcaaa tcgatgataa aaatcaatcg cttcatgaga
    43141 aagataatgg agtgattcgt ctaaagcaat ctcccaaatc tttttttctt cattccactg
    43201 aatactagga tgctggttca tgatcccgat aagcgtatct gtcacattag gtaatttgcc
    43261 gtcttccaac catgcacctt cacattgatt agcagctact gctccgcccc ataaaaaatt
    43321 ttctggaaat atttcctgat ccataactat ctctcctcgc tatcaacaat ttcttacttg
    43381 aagtatagct cgattcatca aaacaagata ttctaactat ttcggcagaa gagaagaaaa
    43441 aaattgaatg ctactcttca tttttaatat ttatatataa caaatacata agacgatccc
    43501 cgaaagaaaa cactcgttaa ccatctaagc aaacgattta ttttacttcc aacacaaatg
    43561 cttcataagg tcgtaaatca actttgccgt ctggtaactg tttcagagga taatttgaca
    43621 caataaccct taaagcttca cgtggaatag tgaacgtctg cttttcactg gacatattac
    43681 aaataacgag ccattgctgg tcttcatata tgcgagaata ggcaaagaca tgctcaggcg
    43741 tcttttccac taattcatag tctccccaga cgatgatgtc atgttttcta cgcaaatcga
    43801 tcaatttctt gtacatataa aaaacagaat cttgatctgc taacgcttct tctgcattga
    43861 tttctttata atttggattg actcgaagcc atggaattcc agtagtaaac ccagcatgtt
    43921 cacgggcgtt ccattgcata ggcgtcctag cattgtctct tcctttcgcc ttgattgatt
    43981 ccaagatttc ctcttttgta aatccagaag aaatcctttc gttatacata ttgattgtct
    44041 caatatcttt tgcttccgcg atatcatcga ttgggcaatt cgtcatgcct aactcttctc
    44101 cttgatagat ataaggggtg cctttcatca tatggagcaa gatagcaaac atcttggcac
    44161 tttcttttcg atacacatcg tcatttcccc aacgagaaac aattcgcgga agatcgtgat
    44221 tattccaaaa taaactattc catccttcat cacctaaaga tgtttgccat ttggataata
    44281 cttttttcag ttcagagata ctcaagggtt tcaaatccca tttgtctttg ccttcttgct
    44341 gatctaatcc tatgtgttcg aattggaaga ccatggataa ttcatttctt ttaggattgg
    44401 aataaagttt agcgatttcg gtagttgctc cccatgtttc gccaacagtc atcagatttt
    44461 tgtcaccaaa agttgcttga ttcatttcct gaagatactc atgcagttta ggtccattac
    44521 ttgtgatttc tttatccggt tctttgccaa tcatatcgat cacgtccata cgaaagcccc
    44581 caataccttt atcgatccag aaattcatca tttgataaat ctcttggcga acctgtttat
    44641 ttttccaatt caaatcaggt tgacgcttgc tatacaagtg cagaaaatat tgccccgttt
    44701 tttcatccaa ctgccaagca gaaccactga atattgagcg caatctatta ggctcttttc
    44761 cattgaccgg atcacgccaa atataatagt cccgataagg attttcttta tttttacggg
    44821 cctcaatgaa ccacggatgt tcatcagaag tatgattcac caccagatcc atgatgatac
    44881 ggatatttct tttctttgct tcttcaatca gttcttccat ttcttccatc gtaccgaatt
    44941 ctgccatgat tgcttgataa ttactgatat catacccatt gtcatcattc ggagactcgt
    45001 atactggaga aagccaaatt gcatcaatac ctaaatacgc cagataatcc aacctggaaa
    45061 taatcccccg caaatctcca ataccatctt gatttgaatc ttgaaaactt cttggataga
    45121 tttgataaac aactgaatgg tgccaccatt tttgttccat gattttcctc ctataaatgg
    45181 atgtttctat tttttgctta atcatttatt ttagtctctc tcactaaaaa ttgtaacgct
    45241 ttcaaatagc tattgcacct tgttatcggt aacagaataa aacaaaaaaa cagctgagga
    45301 aattccctca actgtttttt gaaaggattg atttatgcag ggaagaatgc tgatttcaca
    45361 acttctttat aaacggtgtt cactcagctg tcccttggta ttagctcaaa aaacggcaaa
    45421 atataagaaa ctattttttc gtttttttct ctaatactca ggccagaacg ctgatttcac
    45481 aacctcttta tttcacattc aatatccaca tgaatcccac aaatacaaag aacagaccat
    45541 acatgattgg agatacttct tttcctcttt tagctgctaa catggtaatt ggatagaaga
    45601 taaaacctaa tgcaatccca tctgaaatac tataagtcaa aggcatgccg atcaagatca
    45661 agaatgaagg gatcgcaatc tctaagtttc cccattcgat ttgtcgcaaa gattgtgcca
    45721 tcaatactcc taccataatc aatgctggtg cagttacttg tgaagtaaca actgatagta
    45781 atggagaaaa gaacaagcct aacaagaaga aaatccctgt agtaatagct gtgatacctg
    45841 aacgtcctcc aacggcgata ccagctgatg attctacaaa tgcaccaaca ggagaagtac
    45901 caaataagga acccgcaagc atagctgttg aatcagaagc taaagctttc cctacacgag
    45961 gcatcttgtt gtctttcatg aaacctgctt ggtttgctaa tccaactaaa gttcctgctg
    46021 tatcaaagaa agtcacaagc aagaatgtca gcactacgac ccacatttga agagaattga
    46081 tgtcccctac atgttttaat gcaactaaaa atgttggttt caaacttggt gctgcggcaa
    46141 caatttcaga aggcattgga atcaaacctg tgaccagacc taaaatcgtt gtagctgcca
    46201 tcccgatgaa gatgccacct ggtacacgcc gaacaagcaa gatagcagtt acgactaatc
    46261 caaaaatcgt caaccaagta gaaccaacgt tgagtgatcc taatcctact aatgtagatt
    46321 cattcgaaac gatgatccca ccttcgctca gaccaaggaa agcgataaat agaccgatac
    46381 cgccagaaat cgcatatttc aaatctgctg ggatcgcatc aatgatcatt tcccgcagct
    46441 tgaagattgt gatcaaaata aaaatcaaag aagcaacgaa tacgccggct aatgctgttt
    46501 cccatggaat ccccattcct aaacaaacag aataagcaaa aaaagcattg atcccaagag
    46561 caggtgccgt tccaattgga taacgggcta atacccccat taaaacacag ccgatcgcac
    46621 tggctaatgc agtcgcagta aacactgctc cttcatccat tccagaagca cctaatacag
    46681 ttggatttac aaataagata taagccattg agataaatgt tgtaaatcct gccagtacct
    46741 cacgttttac cgtggtgttc aatttttcta tttcgaagta ggaaagtatt ttttccttca
    46801 tcttccatcc ccctaaatcc gaacattata aataaagtcc gttaaaattt cgatttatta
    46861 ataaaacaac gtgttttatc atatactaaa acaaaacata agtaaacaaa aaattcggat
    46921 tttaagcaaa atccgaacgt tccatctgat taaatccctt tatctcaaag ttcatgaaca
    46981 ttcactttgg attacaagaa tttctttatt gtgttaataa agtttcttca ttctagtctc
    47041 aaaaatcaat agtgtgattt gattttacca tttcgtttct gttcttcttt gatgaattct
    47101 tttgtatcga caggattcag attatttagt ccgccaaaac ctgtatcgac catttttccc
    47161 cagccttttg tcttcttttt tcctgatttg agattctttg ctcgaagctt ctcactatgt
    47221 tttgctcgcc gatacttcaa ataaccttct aatcttccca ttagatccac tgtttttcct
    47281 cctttttatt caatcagacg actcagcttt tcctataaca aaataattgc cttcagggtc
    47341 agaaaaattg aaagtcaaga tgccattgtt atctgtgatt tctcctggtt cttccatgtt
    47401 ctcgtagata gtttcaaatt catccgtaaa aaatactaaa gaaggcggtg gtcctaatac
    47461 ctctggtgaa aacttctgca caaatacttt tgggaatacg cctaattcta attcttttga
    47521 gatgctgagt acaatactct taaattcttc tggcaattcg attgtttcag aaatttctgc
    47581 accaattttt tctacaaaga atcggcaaat catctctacg tcattgacat aaagcatcac
    47641 acgtgttttt tgtatcatca tttgaccctt ctttctattt gattttcttt cctgtctata
    47701 aactgattcc attatatcac gaaagcgcaa acaccttgtg tttgatacta ttcaagaaaa
    47761 ataaagcaat agtttctagg attgctttcc tccacaaact ttttttacaa aaaaaaaacg
    47821 gcaatgaatg ccgctcttct tatttcgatt cttttataat tctgcttctg attcatcttt
    47881 ggttagtgtg tgtctaacac tagttacgcc aaatgtttga tcgatttttt ccttcaacgc
    47941 ttcgattgcc tgtgcgccac gtgccgcttg ttcagcattg atggattcaa tgaccagcac
    48001 cgctgcttgt gtttcttccg tcagcatcgt tctttgggct tcacgccagt tgagacagcg
    48061 acagatcgct ccttgttcat catagtagat gatttcttcc ggaagtgccg gagcatcgga
    48121 atctgcacct aaaggcagga atgattcgcc accttgggct tttcctaaat gcagatttcc
    48181 tgcgatcttt tcgatatctt ctccgccgca aggtacgcca aaagacaagg aaatactatt
    48241 atagatatct acaagcggat tgattgggaa aaattcccgt tcttgatttg cacgtttcag
    48301 taaagcttca atagaagaac gtgcaccttt tttagtcttg aatgtggtaa atgcctgacg
    48361 ccactgagca atgacttcgt tttggctgaa tgtttcttct gtaaggtaat ttcttgcttc
    48421 ttttgctgcc tcattcaata attgatgata cgtttcttca ctttcttttg ttacgtggtt
    48481 atcgatacca tttacggata agatttcgat ggttgcttca ggaaatactt cccagaaatt
    48541 ggtatccact attacttttt tcatctgttc acacctcttg attagaataa ttgcttgatg
    48601 aatagatagt ctgtttgggg atcatctccc atataaaaaa catgttcgct gtatttgata
    48661 aatccttttt tacgataaaa agcgagcgca acatcgttgt gttcccaaac accgagccaa
    48721 atggctgttt tttgcttttc ttttgctttt tcaatagctg tatctagtaa aaatgtaccg
    48781 ataccttgat gtttaaattt ttttcgtaca tagattcgct cgatttctaa aaaatgatca
    48841 gccatttcct cagattgact cgttcctgta tttagtttca ggtaacccgc aggctcttga
    48901 tcgatactca ctaggaaaaa atcggtttct ttatctttta gctcttctgt aagtttttct
    48961 agtgcataag cttgtgtcaa gtaatcagct aaatgctccg gtgaattatc ttttccaaat
    49021 gtatctgtaa atgtttcgat actaatttgt tgtagtaagt ctacatctga aggcgtcatt
    49081 tttcgaattt cgtatttatt cacggcttct tcctttcaat agatcctttt attgcctttt
    49141 ttgacaaaat tccaatcttc gctaacattc ttgcatactt tatttaaaag atattccaat
    49201 tgttttgctt cttcgtcaga aagaccattt aatgcgactg cattggagta gttgttttct
    49261 cgaatgatga aaggatagat ttctgctcct tttttagtcg gatagagttt cttgattttt
    49321 ttattttctt tatcttccaa acgttcgatc atcccattgg attctaattt cttgattgct
    49381 cgggcagtcg ttgtacgatc tactttgatc atttctgcta gtttttcttg gatgattcca
    49441 ggattttcgc aaatacgtac taaataaaga tactgtcctc ttgttaaatc gacttctttg
    49501 aattcgatat tgctaataga atctagcgct cgggcaatca ttccgatgtc tcgaaggatt
    49561 tcagccattt catcccacct ttattttgtt tgtaagacta gttcacctct ttttgttgca
    49621 aatgcaacta ttttcaataa aaaaatcaag ttctttttta ataactagta aagtatattc
    49681 ttttcttctt ttacgaaaaa gctcaatcac aatagatctg gtttttgttt tctaaaataa
    49741 gtaactgttt cttcgttgtt cgcttttctg atagctttgg caactcttct atactaaaaa
    49801 atcccatgtt ggaagtttca ttattctcaa taaacttggc ctcttcaccg tggatcgcac
    49861 aagcaaaaac aagtttataa tactgaaaaa gctgtggaat atctttttgt ttattcgtat
    49921 caaaaactgc tcgcaactga gtagtttcta ctgttaatcc tgtttcttca tagacttctt
    49981 tacgcacatt ttcttcagga gacaatccta tttcagcaaa tccaccagga agtgaccatt
    50041 ctttcgtccg tttatcttcg attagtagga ccttgccatc ttttttgata taggcacgaa
    50101 catctacttt tggtgttgga tgtccttctc caatcgttgt gagcgctttt atttcttcga
    50161 aagtttcttt tcctatttca ctgatcagtt ccaatgaaat cgtccggatc tcctcaaaac
    50221 gctctttatc aaatacatct tttccataat atagaccagc ttgagaaagt gcgagtagtc
    50281 ttttgtattg agccaacttc ttgttcattc tcttcccttc ttttttagca aatgtatgac
    50341 tatgtaatca agtatagaag actggtttaa ttacggcaaa taaatataat gaaatctgca
    50401 ataaataaaa gaatgttaaa aaactcgaga acaaaagaca ttcgacttct ctggggctgt
    50461 gaataaatgg cgttcaaaag cttgcatctg cggtaataag ccccaccaaa cgaaaaatat
    50521 gacgagctat tcttgtctgg ctgttcttat taattgaggc aggacagctt tttcacaacc
    50581 tccccactaa acggtgttct cctaccaact cctcggtcac aagtcacaat attcatcaaa
    50641 catgagaagc tgtttttttg aaattgctcc ttgtgactcg gagctgaacg acaggctcac
    50701 gacctctcgg taaacagcgt tcaaaagcca atttttcgat attaagccat ttctttgtta
    50761 cttattgtca ttgatttctt tttctaattt atccaatagt ggagtgtaat ccacttgagt
    50821 atagtctgtt acatcaaatt catatagtgt tcctaactgg aatttgtcat attttcggtc
    50881 ggcgatgatc tttttgaatg cttctttcgt aatatgattg gtccctttcg ttcgatcttc
    50941 caatacgtca ccatagtgat aatgatccat gatatagctc aaatgacgat ctgattcacg
    51001 atcacgtttg taccgacgtt gccataacac ttcaaagtct gctgttaggc gaatcgtgat
    51061 cacctgatat ccgtatctat ctgctaattc ttggagtcgt gctttttgct tatcactaaa
    51121 aggatactcg gacacaatca ctttctttcc tgcttccata tacaaatcaa gtgctttgta
    51181 atagaaagga taaactttcg tcctttcttg ttccgcccgt tcttccaaat tgttaaaccc
    51241 gatggattct gcatagtatt ccttgatttc atcgagcgtg atggcataca tatctggaaa
    51301 tcgttcccgt agtttattca taagatatgt ttttcctgta ccaggactac cagccagaag
    51361 aatgaaatac tttttcatct catttatttc ctaagttaat tggactttcc aagttcataa
    51421 acagtccaat cttatgcttg acaatttctt ttactgcttc atttgctgga atcacattat
    51481 ggcgaagaga cttgttgatt tctgtttcac taaaggtttc tttagctact ttcgtccagt
    51541 tgactaaaag ctccgttcca acattgaatt tgcggatccc gttattgatc aattcaggat
    51601 aatcttcttc tttcacacct gttcctccat ggataactag ggggacatca actactgcat
    51661 cgatttcttt cagcaaggga atgtttactt ctgtttttga tttgaattgt ccatgattcg
    51721 taccgatagc aatagctaat gcatccacgc ctgtagcttc tacaaatttc actgcgtctt
    51781 ccggtcttgt atataccttg tcattttcag cgacatggat tccttcttct gtaccgccga
    51841 ttgttccaag ttctccttct acggaaacac cgtgcgcatg ggcatattct actactgctt
    51901 ttgtcttcag gatattttct ttgaaaggca gatgggaccc atcatacatg acagaagtat
    51961 atccgctgtc gattgcttct ttgatatcat caaagtctcg ggcgtggtct aagtgcaaga
    52021 ctgcatcaac catttcttct tctgcaatag ctgtcattac attgactaac acatgcatgc
    52081 cgatatattt agcggtatcg acacttgttt gaataatgat cggcgaaccc atttcttttg
    52141 ctgcgcctag catagcagga agcatttcta ggttatgcgt attaaaagct ccaactgtaa
    52201 aattcaactc ttctgctgtt tttgttactt ctttcaatgt tgtatacatc ttttattgcc
    52261 accttatctt tttatttgtt tcctttgatc gttacttgtt ttgcaatttg tcgcatctca
    52321 tccattttgc ccatgtagta atcgatccct tgatcatcac cagcacgagc agcatctgca
    52381 cgcttctggt tatagaggct catcagtttt ttatacccat ctccgatcgt ctgtttattt
    52441 tccaaactct tttctaaata ttggatggct tgatcgttca catacaattc agaaaattta
    52501 agtccaactt gttcataaag tttcgctaat ttatgcttat cttgggtagt ggaaatctct
    52561 tgtttcaatt gtgtaatctc tgattgaatc ttttcggtcg cttctggcga tagggctttt
    52621 tcttcttttg ccagaacttt tttcggttct ttttcttttt tcttaaaaaa tccaaacatc
    52681 attttcccta ctttcaatta aaatgctttc aaaactgggc ttaagatcca ggcatataag
    52741 agtgctgcgg ctactgtatc tacatcggtt gctgtagcat tgttgaatcc catcgaatta
    52801 aagatcgtta ctagcaaagc gggcaataat gtaataaaga aaccatgagc aataccgcca
    52861 atgatcgctc ctcggcgtcc gccaactgcg ttgccaaata tccctgctgt ccctccggca
    52921 aagaaattgg ttagcatacc aggtaaaatc atcgctaagc cgaacatggg caaagtaaac
    52981 atggcaataa tcgtaccaat cgttgtcgta atgaaaccta aaatgacagc atttgggcta
    53041 taaggaaaga aaactggaca atctaaggca gggatcgcat caggaactaa tttcatagct
    53101 atccctcgaa atgccggcac gatttcacct aacagtagac gtacaccagc tagcaataca
    53161 tacacaccca ctacgaattg gatggcttgt aaaaaggcaa acatgatata gttttgatct
    53221 cctgataatt cagaagcgaa tggttcgcct gcaaataaaa cagtgatgat atatagcggg
    53281 accatcacga ccatgacaga caaataagta tcttgcagaa attcgaaatg tgtcggcaac
    53341 ttgatatctt cgatcgactt tttattttcg cctttctcac caaaaagctt agcaacaccg
    53401 gcttcaaata agtacccgat cgtacaaaaa tgacctaaag caatatcatt tgatccagtg
    53461 attttacgaa tgatcggttg cgctactgcc ggcatagcaa tggcgaaaca agctccgata
    53521 aaaccaccga ccaagatcaa tacgatccct cgcagaccgg caaaatagcc aaagactgtc
    53581 gtcatcgttg ccatccataa aattgcttga ccagttaaaa aaatgtactt ccattttgtg
    53641 aaacgagcca aaataatatt gaatacaaaa atggctaaga acgtcagtgc aatatctcta
    53701 cctaaaccca aatcattcat tgcttgacca ttgatagatt caatagaagg gatgatccct
    53761 tgcatatgaa atccttcagt aaagattttc ccgaaataag ttaaacttcc aacgatgatg
    53821 ctcgaaccgg cactcaacac ttgaaatcct aggagtgtct ttaacgtgcc agagatgact
    53881 tgtcctgctg atttcttctg cagtagtaga cccaacatag caatcaatgc aatggtgatc
    53941 gatgcctgag tcaaaatatt ttcgatgata aaattgataa cgcccatgtt tttaccctct
    54001 tttctttttg tatttagata actcccttat cttgcagaac tggggtgatt ttttcttcaa
    54061 tttcattttt tgaaacaata tttttcaaat agatcatcgc cgttttagga tcaactgcga
    54121 acttttcgaa ctgcgaacga aaattttctg ctgtgatgat cacatctggt ttcatggaaa
    54181 ctgcggaaga aatatcacaa tggtccagtt tggcttctac tcctaatttg ttcaaaacat
    54241 cctcagcaga catctgtgct gcaaaactac ttcctaaacc tgcaccgcat acgaataaaa
    54301 tgttcaattt gttcatcttt gttctccccc gtatcattta ttatttctca actactgaaa
    54361 aaagcagttg tttgaaatct tcgatatttg tgcattcaat caatcgatcc aacttctctt
    54421 cgttgttgat caattcaatt agttctttca tgatgttcag atgcgagtag gagtctactg
    54481 ctgccaaaca aaaaataatc tttactggat ccatttcagg attaccgaaa tcgattggtt
    54541 gctcaatcgt agctacgctg actcctaatt tattgacccc atcttctggt cgggcatggg
    54601 ctagtgccat gtgtttgcca atcacgatat acggtccgta atcattcact gcacgaatca
    54661 tcgcttcgac atagcgctct tcgacaatgt tttctttaac caatggtcta gcagctagtt
    54721 caatcgattc ctcccaagta gtggcttttt ctttgatcat gatattgctg tccgtcaaaa
    54781 tatcttttaa cataggctgg atctcccttt tgttgatttc taaattgttt gtttcgaata
    54841 atttttctaa cttgccatag atgattcgat ctactcggcc accactttct ttcatgacat
    54901 ctattatttg agtgaataac tccgtcgatt catgactgtt aggctctaac cgctgtagtt
    54961 cttcatttct tttcaaaaag tcttctataa ccaagatatt cgtctcagtt aaaatcggat
    55021 cgacaactaa aagcggctta tttcgataat tcaattgaaa ggtgctgaaa accagattga
    55081 catccaattt atctactaat tcgatttctt ttgaacttaa aactgcagta atctcgatct
    55141 gaggaaactt ttctttcaga ttctctgcta acagatttcc agtagccatc ccatggttac
    55201 agacaacgac tgatttataa acataattca agtctcgctt gattacactg gcgatcgtcg
    55261 aaaagtggat gacaagaaaa gctatctcgt cctccagtat cttgccacca attacttctt
    55321 cgatcgtagg aacaaaatga gtgactgcgc ggtagattgg gaaataattt gttcggatgt
    55381 tttctttcaa tggattcatg acttggatat gattcttgat tcttacaatc agtgcagcca
    55441 tgtgcttata gagattttcg aataaagctt cttcctttag atggaaaggt acgtgtgtct
    55501 cgttctctac aaattggatc aattggatcg ttagtaattg agcttgtacc cactcgattg
    55561 aattggagat atctctagca ttgaacgtct caatagtgaa acgaagataa tttctttcta
    55621 cttgcgggac attgtccaat tgaaattcct cgatcatgtg gtcaataaat gcagaaaagc
    55681 tactgtcttt tatttctgta tttttccaat taatggcaga gataaattca tgtttcctga
    55741 ttcgctggat ccagatcaat gtaaaaagca ggatttgttt tttataaata tcatcttctt
    55801 gtttcaacaa cttattggaa tagatctcct gtattttttt gatttccacc aaaggaaaat
    55861 aatggagaaa gattttttga gccggtgtta attgtgcatc ttgattcata aagaagtcgg
    55921 tcattcccag attctgattg ataaaatcat agatcatcgt acggatagat cgttctgaac
    55981 ctttataaac cagtccttgc tttccataac tgacgatctc tatcccataa ctgaccagtg
    56041 ttgctcgtaa ccgtctcata tcttcatcta atgtactttt agagatttga aattcttctt
    56101 cttttttgtt tagatggatc gggattcggc tgtaagcaac ggctaaaact agatcaaaaa
    56161 tacgttcgcg ccgattcaaa aagccgtctt tcacatcttt tatttcagtt tctaatcgag
    56221 cttgcttttc cttttccagc ttcaacaaaa aacctttgtt gcgaattgta cggatctccg
    56281 gaagcttttt actgctcaac cagatattcg cttcaagaac ttcctgacgg atcgtccgct
    56341 gactgacatt gaactcactt gctagatgtt ttgcttttac tggatattgg gctgtcatga
    56401 ttctgtgaag tatttcaatt gttcttgttt tcatagaaat gatctccttc tgatttcaag
    56461 tatatggttc cgcttacata ataaaaagta gatatttctg ccacttgaag tggaaagaaa
    56521 gtaagcaaag caaacaaaaa ataagccata tgctttttca tctcctcaac gaaaaagaca
    56581 tacgcctatt attacaaaaa ttttgcccat ctatacaaaa aagaggttgt gaaaaagctg
    56641 tcctgcatca agtaataaga acaactaaac taaaatagtg cttcctattt ttcgtttggt
    56701 tgttcttatt atcgcagatg caagctttta aacaccattt agtggagagg ttgtgacaga
    56761 gatgttcagc cttgagcgat aagaagcgat tttgaaaaat cgcttcccat attttacaaa
    56821 atcgtgcctt attgccgata ggctatctct ggcacaccgt ttattcagaa aaaggagctg
    56881 cgacaaggct tttgtcacaa ctccgttcat aaatatttcc tgtcaatcca gcataatcgg
    56941 ctgaataaaa tcggcttgcc atcttttttc tttctcagaa aaatcaaaat accatatctg
    57001 agaaaaatac tgtcgttgtg tcttacttcc tgagatcaat cgcccatctt ttcgatcgac
    57061 tgaataatca cagcatctga aatcaattcg gatggcaaaa ctattttcgt ggatctgtcg
    57121 ataatttcct acttcctgaa tagttatttt tttagtatga tttcttacac cgtctgcttt
    57181 gtttttttgc agaactttct gatgttcggc aaacagcttg tctgtataac agcttctggc
    57241 tttttcagga gtttcttctt cccaagcgga ttggatcttc atgaatatct tttggatttc
    57301 cagaaactgt gctttctttt ctttagccgt tcctgacatg cgggacaata tctccgcttt
    57361 cagccttttc ttttgtcttt tattcttgac gatagaaaaa gcagaaaccc ctcctactga
    57421 caaaacagct aatgcaagaa atcccgtttg ctcataacta gaaggacctg tacctggacc
    57481 ataataccca taagaatctc tgccgtaaga acgactgcca aaataactgc ccccatatga
    57541 acgaccacca aatgaacctc tgcccgaact tcgaccgcta gatgtacctc caccatgacc
    57601 acccgcgaca gcgaatcctt gggtcggcag agcaaacaaa cataggccca ctaacaaaat
    57661 gattgctaaa taattgattt ttttcattgt cttcctcgtt atcttttatt acaaaaaact
    57721 atttttatga tagccttgct aaaaggaaga gtcaataacc agatgcataa actgtttttt
    57781 tagcaatttt gtcttattta gtcattgagt aacatcggac aaatgtatgt gtcggcagtc
    57841 cataattcct ctatcttcag catgaacaag cttgcagaca agagatctgc gcttcctcca
    57901 ggagagattt ggttttcctg acaaaagtgc aacagtgctg taaatggacg atttggtaaa
    57961 gcactttgac tagcagcatg agcaagtttt tgcatttcca ctaacgtttt ctgatcactg
    58021 cgatgcaata cgcatgtgtc atctagcgaa ctcatcaaaa ctaacaacat atgcatttgt
    58081 ttctgtacat atgaatcatt atctagctcc ttagctgctt gaattgcaag cctgatatgc
    58141 ggatacccta atatcgcttc ttcatatgca ccatttacgc catatttttg cttcacccta
    58201 tgaccatgag tggttttttt atgacgatat tttgtatcag gaaaagcagc aagcttgctg
    58261 acatcatcaa gtattttcga taaagaaaaa ggctgttcca tactgatttt ttgtgcaatg
    58321 acactgatca atagccccat tgcccaaatc gctcctttat gggtattgat gccatttgta
    58381 gcaatcagca ttgccttttc cgcttttcgc ccaatctcag caattctttc tcttaactcc
    58441 tgatcaatag catgatgcca tgctatttga gccatttctt caaaaaaagg agttagcgtc
    58501 ttagcagact taagaaataa agcatagtcc atatcggaat gtgcacccgc atccagtgca
    58561 tccactaatc caggttttgg acttaatgtt acttctgcga tcaatgcttc ctctaccaac
    58621 gcagcgagtt gctgagtcac tgcttttttt cgttcgtcat ttatcatgac actcactcct
    58681 tcttcctact attacttgct gaaacctttt ttgatagcta cccaaatgat atgaagtaac
    58741 cagcttaaag caaatgcaca acttgccgtc attagataag ctacaagaat catgactcct
    58801 gaaggtaact gcagccaact atctttaaac aataataaca gtacttggaa aacaaataca
    58861 ttggctaaat acgtacgata agcataaaca gacaaccatt tgaacaatgg caattttggc
    58921 gaatcgttta caatcatttt ggaagcgcct atgaagacag caaagatgat gactaaactg
    58981 tataaacttt ggatcgtatt caagtaaggt gcattcgcaa agctcaagtc tcctggatgt
    59041 gcgagcaatg aacggacaga aaagaacgcg ataactaagg caacaggtaa gaaaagataa
    59101 cgtactctgt ccaaatattg atagactttt tcgtgataaa caaatgcggc taccccataa
    59161 atcatgaaac tagcaacaaa ccgatctaat aagtaccagc tgtcatgata aggcccagtc
    59221 aatacttgtg tttgatagaa cagataccat gcgacatata aaatcgttga accaatcaat
    59281 actggccata catatttttt attagcaaat actttgtaac cgagccaaac aaaaaacggc
    59341 atgaacaatt ggatctgcag catcataacg gtataccata aatgaggcgc tccatcacct
    59401 gtgacatatt tcagtaaaaa gcttgcagta tccgtatacg gagtttgttg ttggactgct
    59461 ggaaatagcc aaagataagc cgtcgtccat agaagatacg gaacgactag ttcaaaaaac
    59521 ttttctttca aaaattccca ataagacaaa tgctgacttg tttttaccat attataaaca
    59581 attgcaaaaa taaacattgg tgctgtgtat ttaacgatga cgtaaaaggt accaagaaaa
    59641 gctgtatttg ttgcgctgtg gctgtttgcc aaagcaaagc tcaatatcgt ttgcatcata
    59701 acagccgtta cagctgatac tttctggaag tcacttacgt tgattttgat ttttttgttt
    59761 tcaaacatct ctttctctct ctttttcttt attaccaaag ttctttggtt aatttaggtc
    59821 cttcgactgt tttcaataga atttttttct ctggctctct caaatactct tttagtgaaa
    59881 aaccgccttg ccgagtcact acttgggtat cgaattgctc aaaaaaagca ggatgcgatt
    59941 gaattacctg aattggcaat tcaatcggtg aatttgcgta cagcagcaaa tcaaaatcac
    60001 tggtttcttt tactgccgga atcccagtcg ataattcaaa tcctaagctg ccgccgattc
    60061 cccatttaca tcctgataat atgtttctag cagcatgaaa ttgctgataa acaggataat
    60121 ccatgatttt ctcttgtcta tacgattctt gttcgatgat gtcccacgga tgaatgactt
    60181 gtttgacggc atgttttgag atttctgttg accatctctg attgcgggca ggtccacgta
    60241 aaccaatcgg tagtatttct gcgtgatccg tcgacgcacg acgaactgtt ccgaacatct
    60301 tttcagttag aacgacccat tcaggcaagg tgaacccttc tatttcatgt ttatcaaaaa
    60361 ggacaatatc atgtgcttga atcatttttt atgcatccca ttcttcgtcc attttggcac
    60421 ggactttatt tgtttcgaca cgtccgaatg ttttggctgt ttcgtttgtg tatcgatttg
    60481 tcagcatcgt gtcatttgta ttgcggacat cttgaatggc ttcattgatt gcttcgatga
    60541 ctttgctgac attttgttct gaagcagctt ggtcggtgat atcttctagg aaatgataga
    60601 tcgctcctag ttttgtataa ttattgatat cgtaagcgat agctggaact ttttcagcag
    60661 ctgcttcgat ttcagcaacc gaacgttttg tcacacgtgc agcactttct ttagacatcg
    60721 cttggacggt aatttcttta ttgtttaaag caatcaagcg gcttgattgt aatccatgtg
    60781 ctaaaaatgc acctgaaata gcatttcctg caatcaatcc aataactgga tgtccagctt
    60841 gacggagttt tgcataagca gcagcactat tagccaaagc cacatggata ccgatcaatt
    60901 cttcgttata gccgtatgct tggcttggta catcgatcac aacgatgatt ggccgtttca
    60961 cttttttgtc tttatcttct tcgtaaacgt gatccaaaat ttgtcccatg cggaaacctt
    61021 caactaaacc aacttcaccg tttcgtacac ggtacatcgg gtttttagga tcaggtacga
    61081 ttgatgtcac gatggcttct tctatgaatt tacttgattt accataatac acagtactaa
    61141 tagaagaagt tggatttttc atgccagtta gtgccgcaaa ccaatcgtaa ccaacacttg
    61201 ctgcagctgg ttcatttcct tctgctactt ctggtaagtc aattgatttt gcttgatggt
    61261 tagcaattgc ttcattgtaa tcgtcaatgg ccattggttt tgaaagatct aaagaatcaa
    61321 gtaatgataa ataaaatgct gagctttcac tgcgatgcgt gtcttttcgt tcgtccattg
    61381 ctgcgatgac agcagctttg attgcttcta cactatcagt cactaattca tcaatgattt
    61441 ttgattctac ccgttgacga gatcctaatg tattccaaat caagtctttg tcactagaat
    61501 caaattctcg aacgcctgct tcttgttcaa taacttctgg tccattcaaa ccgactctcg
    61561 ctttttttgt tgcgattaaa taactcatta atgctgaagt aatcgacata ccgccaaatg
    61621 atcctacacg tcctggaatc aaaccgatga ctggtacata ttgttttaga gcaatgatta
    61681 catttccgat ttctgaaata gataacagtc cgtagtttgc ttcttgcaaa cgaacaccac
    61741 ctgtatctag tacaatgact ggaaagatct catttccttt tttattttct tctaacacat
    61801 gttcaagtgc agcaacgatt tttgcaccgg aaacttcacc gataccgcca ccttggaatt
    61861 ttccttccat agcgattact actgcttgtt tgccattgat cgtgccacgg ctgacaacga
    61921 tcccgtcatc actttcaggg acgattcctt gtgctggtaa acttggcgcg atgatttgat
    61981 cgaatggatc aatcaattca cgtccattgt caagtagagc gttcactcgt tctctggcgt
    62041 ttaattctac aaaactattt ttcatctgaa agttcctcca ttgcttgcgt caatcgtagg
    62101 tacacaactc ctggtgtagc accgaagtca ttgatcacga tatctgctga aattggataa
    62161 cgatcaaaaa atctcgttaa tacattgttc catacttcgc cgaagccatc gcttcctgta
    62221 caaattttta cagtagattc tgttttttct gttggaaaca tcaagatttc caaatctcct
    62281 gaaccgacca ctcctacatg gattttctta ttgatcggct gtttcgttgg atatttataa
    62341 gctaattgtt ccatggatct ctcccctttt tgtaaaacag agcatacacg ttctgcttat
    62401 tcgtctttct tcttccatct gggtaaatgg cgacaaaagg tttttctcgc caattttatg
    62461 accaagttct gaatttcatt ggtggttcat acaggccatc tgaccattcg atcaaatcat
    62521 cgatggtttg tgcagctaat aatgaacgtt tcgcttcact acgtttgatg cctagatctt
    62581 ctggtaattt cacgatgccg gctgcacgca agctatctag tgattctttc gtgctagtca
    62641 ttccaagagg tgtaacaccg ccaattgctg caattgctgc ttgtcgttct tcttttgttt
    62701 ttgctttgta caaataagca attccttctt ctgtcacgat atgtgtagta tcttcgctat
    62761 aaatcatcac tggtgcattg gctaagcctg cttgtttttg aacagctagt gcatctaatt
    62821 cttcgacaaa gactggtttt ttatttgaac catatgtttc aaccatttga acaactaatt
    62881 tttggccttt ccctaatgga tcatcattgt cgcgaagtga ttgccatgct ggtgtagaat
    62941 gacgacgacc gccaggatta tgtcccatgt taggcgcacc gccaaaacca gataaacgtc
    63001 cttttgttac ggtagaagag tttccttcgt aatctaattg caaggttgaa ccgataaaca
    63061 tatcgatggc atattgtcct gcagcttgtg ataatgttcg gttactgcgc atcgtgccgt
    63121 ctttaccgac aaaaaagaca tctgggcgag cagcaatata tttttccata ccaacttcgc
    63181 caccaaaact atggatgctt tcaacccaac ctgattcgat ggctggaatc atcgttggat
    63241 gtgggttcaa tacccagttc ttcgcgattt tcccttttaa ccctagtgat tcaccataag
    63301 ttggcagtaa caattcgata gctgctgtat tgaatccaat accgtgattc aaagattgta
    63361 cgccgtgttc tgcgtagatt cctttgattg ccatcattgc cattagaatt tgcaattctg
    63421 tgatgttttg aggatctcgt gtgaataaag cttctaattg ataaggttta tctgctttca
    63481 cgacaacgtc tacccagtca ccagggatat ctacacgtgg taaagaatcg acaacttcgt
    63541 taacttgaac gatcacgata ccatctttga aagctgcagc ttcgatgatt gttggtgttt
    63601 cttccgtatt gaaacctgtg tacaagttgc cgtctttatc tgctttatct gcagctacta
    63661 aaacaacatt tggaatcaaa tcgatgaata agcgtccata aagttccaaa taagtatgga
    63721 tatcacctaa tttcattgtg ccgtcttcaa tcatttgggc gacacgcaag ctttgtgcac
    63781 cagcataaga gaaatcgatc ttgcttgcga ttcctttttc aaaaatattc aaatgttctg
    63841 gtcgtgagat actagacatg atcaaatgca gatcattcac tttttctgca tctacttttt
    63901 caagactttc tgaaagaaaa cttgcttgtt tttgattgtc gccttctaat acaactttgt
    63961 cgccgggagc aatcagtttt tccattactt ctacgatttt ttcagtttct acatacttgc
    64021 cattgagcaa gttgctgatt ttttccaatc gctgcgcttt tttttcgcgt ttagaagccc
    64081 agttgcggtt tggtttttcc ataattagtc atctccattt ttgatataga aacgtggcgt
    64141 catcaatacc atgttggtct agattgatcg tacggatccc tttatctaca ccaaattttg
    64201 tatgaatcag ctttgtcaaa gtattgccgg ggggaaattc aatcgtcaga tccattccta
    64261 attcttttgc caagtccatc atttggttcc actgcacagg gaaagctagg ttttccaaca
    64321 aatctttacg aatctcttct gcgtcctgag tggctcttcc atccgtattt tttatataca
    64381 aacatctagc atcagataga tggacagact gcatatacgg cttgaatttc ttgaccgtat
    64441 cattcatcaa gagacagtga gatggcacag ggactttcag cagcttcgct gtttgcgctt
    64501 ggtgccgttt ggcttctgcc aacgtaacgg ataaaccttc gatactccca gataacgtat
    64561 gttgcatcgg acaattttca tttgacagat aaactggatg gtcaggatca aatgtttttg
    64621 ctacaatttc ctcagcttcg cttctcgtca cacctactac tacgcccatt gcataaccgc
    64681 ttggataagc ttctttcatt aagactgcgc ggtgatagac tagttccgct gcattctcaa
    64741 atctcaaaga tcgacaagca acagctgcac aaaaagcacc aatcgaatgt cctgctgcaa
    64801 tatcaggctg aataccgttt ttttccattt catctaaata aaatactgct tttgtcagta
    64861 atgctagctg gataaaaacc gtatcttgat agttttcttc tttatcaact aaccgatacc
    64921 ccgtcacatt ttctaaacgt tccatgtaca tttcagggat atccgctaac atccctaact
    64981 tctgactgcc ttgtccagga aataagaaac ctgtactcat gagcctcgcc tcctcagcac
    65041 ttactttttc cactgctatc ttagtcaatt tctgctataa taaaaaatgc caaaaaaaga
    65101 aaaaaccata acaaaaaggt atggatggga tggataatta tgaaattgct tcatctgcag
    65161 tattttaaaa aagtattcga aacaaaaaat gttacccaag cagccaaaga attatttatt
    65221 tctcaacctg ccttgagccg tgcgatcaaa catttggaaa acgaattagg tgtccctttg
    65281 ttttaccata gcggcagaaa cattgagacg accgtttatg cagaagaatt ttatccatat
    65341 gcagtcaaga cattagacac attagaagaa ggaatcaaat tattgtcttc ggtcaatgag
    65401 aagatcgtta cttccgtcat attgtattta gaggtagcct ctgtttctat tccgaacttg
    65461 gtccgaattt ttatggaaaa gcatcctgat atccaattaa cgatcatgca acatcattta
    65521 ccagatgata ttaccgatcc tgtactgtac atcacttcgg agatgaagcc tggcatgacc
    65581 aatattccta tcatgaaaga acctgtttat gtcgccattc ctaagaaaca tcctcttgct
    65641 aaaaaagaac atctgcaatt agaagatatc caacgcaccc ccatcttgat gctgtcaaag
    65701 agcaacgcct tccgtcatac actggatgca gcacttgaag cgaaaagtat cgaattgacg
    65761 atcagttcga cgacagatga tcctgcgaca ttacgttcta ttgtcaagca aggattagct
    65821 gttagctttt tcccaaaagt ttcttggtct tacgataaaa atgatccttt cgtcttgcgg
    65881 gaaatcaaag atttgccctt gacacgaaca atttatttat cttctagctt cacagaagat
    65941 catcctttga tcaaaatgat tgcaaaaacg atgcgggaat tttatttagg aaaataaaaa
    66001 aaaaagagct gggacaaaat tcttgtcgca gctctttttt cgaacaaacg gtgttccaga
    66061 agtaatttct tagaaaataa gccgaaattt cccaaaaatt tgagaagcaa ttttcgtaaa
    66121 ttccttctta tttcttgaag ctaaacattt ctgtcacaac ctcttctcta ttgtcctaga
    66181 cattcattgc gttgatttaa aacttccatc aatcaaatct gctagttcat ctagcttttc
    66241 tattttacgt agatcaatag agatccaatg ttctttattc atgtgatagg ctggaaaata
    66301 cccctctttt cctcgcaaaa ttccgccaag ttcaggatcg accttcaaat caagaatatt
    66361 gatgatccta tggtcacttg catcatcata gattttttct tctggaacag acatcaggac
    66421 cccaaaccat tttttgcttt tttgatgtct gaatacgcaa taatcaggaa attttttaaa
    66481 aatatattct ggagacaaat tgtatgtttc attgatgtga tcgattagtt cttttttcgt
    66541 tagcatctgc ttccatctct ttcttattga ttcgctttat tcaaagatac cacgtaagaa
    66601 tagaaaaatg aatacaagta gttgctaatc aaatacttcg atatttttct tttttatcaa
    66661 ctcttaaatg ttcaatccgc ctgtgttggt cttgctacca tctactatta aaatgtttat
    66721 tattgtttgc ccacctattt tttgatttta gtggtatcat ttttcaagtt catgatgaaa
    66781 ttcttatcat cagtaaatgc tccagaaaaa taaacaatga ttgaaaaatc agttgaaact
    66841 tgaccaccgt ttattttctc cgtattctta gaatagaagg gagtctgatt gatgtattca
    66901 ctaatgaaaa aaatcattac cgaaaaagat attcgacgtc atgtttcttt agtagaacaa
    66961 ttgctgaatc atacaaagat aaccgtaaat gaattagctg aaatcatagg gacaaccgaa
    67021 cgaacgattt tttctgacct tcaatctatt cgctctcagc tgcccgaagg ctgggacatc
    67081 atcagcgatc aagcaggaat cagtttgcaa aaccagcaaa atttattaac aaatgacctt
    67141 tgggagattt ttttcaaaca atcagtcagt gtcgaactgc tgaaaaatct gctttttaca
    67201 aaaaaagttg ctgtccctga ttttctagcc gaccatgggc tttcttatgg gacattgaaa
    67261 agacatgtga ctaaaatcaa tcagcgttta gcaagttacg acttgcagat cgatttgacg
    67321 aaatatacag cttgtattct tggaaaagag cgtgcgattc gtacttttta tcatcgattg
    67381 ctgattcctt tcactcataa caactatttt ttcgaggatt attcgatcca tgaatcccat
    67441 tattttcaat ttttaagaaa cctcagtcaa actgaactag cggttgaaac agaagagatt
    67501 ttcggaacat gttggttctt tatcaatacg atccgtataa aagcgaattg ccgattagat
    67561 tcttctatcc ataccaacag cacactctcc tccctgtatg actctgcatt gaaaaaattg
    67621 tatttaacgg aaggtattta tcttaaagac actgagcttt cttttgcttc tttctgcttt
    67681 ctggaaagtt ggaattacaa caataactat ggacaagaaa ccgctcgctg cctgcatcat
    67741 tctccatttt tagaggtcct cgaaacgttt gtagaggaac tagcttcaga gctgtctctt
    67801 gatcaactaa aaaaaacatc tctgactgat aacttggctc tcctcatatt aaaatatcat
    67861 gaatcgccga tattgattga agcattggac cgtcaatacc atcgtttttt agaaacatat
    67921 gatcagcaat atgcacactt gtatcaacag aaagagaatt tactgaacga tctaaaaaaa
    67981 gaaatagaaa tcaatgaacc aaattacttt ctccaactct tgtctctact gatccaacaa
    68041 acgatttttt ctatcaaacc gaatttgttc aatgtctatt ttattttcca aggagaacct
    68101 tcatggaagg cgttcttgca gcaggaatta aaagattact taggaaaacg tgtctgcttc
    68161 ttacctatcg aactaaccga tctttccact atttcttttg aaaaaacaga tatcttgatt
    68221 tccaatttcc ctctagattc tctagatatc cctattgtat acatttcttc tattccaacg
    68281 aaaaatgagc tcaatcgttt gactgaactc actttcaaaa cttttttata gtaacggcta
    68341 gcgactgtat tctctagctg ttttttcttt tttgcgaaac agtttgttca tgatcccttt
    68401 ttctatttct acaactaaga atagaagaat cacatttgct ccaatcaata actgttgtgt
    68461 catcgttaaa cttactgtac cgatcagctg ctggccgact ggtagaaaaa taaccatccc
    68521 ttgcaataaa gcaaggatac ctaatgaaag aaaaagcgct ttgttttgca aaagaccttg
    68581 gttcaatgac ggcttggaca actctctgca attgatcatg taaacagctt gagctaagac
    68641 gatattttgc agaagaatgg tttgctgtaa gctttgccct tcaaactgca tagccaataa
    68701 ataggcagga accatgatca gtagggagac atagatgatc cgaaacaaat gataaccaga
    68761 taggattcct tgctttggat ctcttggtgg gcgcttcatg atttctggat ctggcgactc
    68821 gaaccctagt gcataagata aagtgattgt cgttaccata ttgacccata aaatctgtac
    68881 tggggacaaa ggtagcgggc gattcagcat aagtgcccaa atcaagatca atccttgagc
    68941 taatgcagtt ggcaagaaga aattgatggt tttttgcaaa ttatccaaaa tccgccggcc
    69001 ctcttttacg gcttttgcaa tcgtatggaa attatcatct cctaaaacca tatcagctgc
    69061 ctgtttgctt acttcactac ctttgattcc catagcaatt cctacatcgg atcttttcaa
    69121 agcaggtgca tcatttacgc cgtctccggt cattccgacg atttctccat ttttctgcaa
    69181 agctttaaca attcgcagtt tatgttctgg tgtcgttcga gcaaagacat cgactattgg
    69241 cacttgctga atcaactctt catcagacat aagatccaaa tcgatccctt ctaaaacttt
    69301 ggcagtatgt tttaagccaa tttgttccgc aatcgctttt gctgtgtctt tgtgatcccc
    69361 tgtaatcatt ttcactgaga tccctgcttg ttggcattcc tttacagctt tgactgcact
    69421 ttcttttggc ggatcgatca atccggcgat ccctgcaaaa gttaattggg ttaaagtctc
    69481 atgcgtgagt tcctgtttcg aatctacttt tttataagca aatcctaaaa cacgctgacc
    69541 ttttctcgca aattctgcag ctgtctgact ccatgcttct tgttctgcag aagaaagagt
    69601 tgatttagca aataatactt ctggtgcacc tttgacgtaa atcaccgctc ctttttcctc
    69661 cgcatgcatc gttgccatat atttgtattc agaactgaac ggaatctttg cttctatttt
    69721 tttcaaaggt agattggctg tttctgtgtg tcgaatcagc gcaacttctg tcggattgcc
    69781 acttaaattt tctgttttct gttcttcttt tgtttttaat tcctgacagt ttttcataat
    69841 ggacaacacg caggcttctt cttttgcagc tacatccaca actgtcattt cattttttgt
    69901 caatgttcct gtcttatctg aacagatcac tgtcatagaa cctaatgttt ctaccgaagg
    69961 aagtcctttg atgatcgcct tttcttttgc catttcatgt actccaacgg atagaatcat
    70021 ggtcaaaaca gctggcaatc cttcgggtac cattgacacc accaaagcaa tcgtagccga
    70081 aagaagaata tgccaatcca taccatatcg aaatgtcgta aaaataacta agaataggct
    70141 caaacaaaga atgccttgaa aaatttgttt gtttaatcgg ttgatttttt taatcagagg
    70201 cgtcgtttgt tgttcgaccg attgcaatgc ttgattgatt ttaccgattt ctgtcgtgtt
    70261 tcctgtttct acaacgacac cgactgcaga accagattgt acaagcgttc ctgaaaaacc
    70321 catatttttc tggtcgccga tcgattcttc ttctgtcaaa acggcatgac ttttttcaga
    70381 tgcttctgat tctcccgtca aaatcgattc ttccactaat aaatcatgtg cttcgattaa
    70441 tcggatatct gctggaacga catctccggc acgtaagaca atgacatctc cttttaccag
    70501 ttctttcgca gggatttttt cttgcatccc gtttgatagt actatcgctt cttgtcccat
    70561 cagctgcttc aaaccattca atgattcttc cgcttttctt tcttgccagt aactaacgag
    70621 tccattgacg atcactacga ataaaataat acttccttca atatattcac tagaagcaaa
    70681 tttcaaaaaa gaggcaatga tcaacacgat catcagcaga tcagtaaaat gctttgctat
    70741 ttttttccat cgttttgtct gctgccttgc ttttatttca ttatatcctt gatcagtcag
    70801 gcgtttctgt cgttcttctt gcgacaagcc ttctgttgat gtttgatagt ttttcaatac
    70861 atcttctacc gtcaatctgt accagttcat cctatcccct cctgtttaat tgatactgtt
    70921 attatacgca gggaagtttt ttcaggcgta tcgattattt caggggggtc tgaaataatt
    70981 cgttttgcaa aatgtatctg ggcctaactg atatttctat tgcttattct tttatataca
    71041 aaatttaaga atacaaacca gataaccaat aaaaaaggaa taaagcgtgt cgtgctttcg
    71101 aataacaagc tgaaagcaat tgaagtaaaa aacaccaaca aagcaagatc tttatatctt
    71161 tgtgtagtgt tccgtttctt ttctttaata aattgaacat gtgcacacaa gatcgaagac
    71221 cacacaaata gaaaacaact cgttgtcatg cctgccaaaa gctgaaaaaa caatcgacta
    71281 tcagctacaa aaaaatgtag acaaagaccg gcaaaaaata acattcctgt aattaaaata
    71341 ccgtgtaaag gtacgccttt cttagaaagc gcacaaaacc aatggggcaa acttttttct
    71401 tttgctgttt gatataaaat cctgctagta ctgtagactg cactatttgc tgaggacaaa
    71461 gaagcaacca aaatcattag attgacaatt gctgctccgc cttggcaatg gatcacttgc
    71521 agcatagtca ctaaaggact ttcttttaaa tctaaacaat gccatggaac aacaaataaa
    71581 atcgacaaaa tcgttcctat atagaaaaag agaatacgcc aaggcagaca gttgattgct
    71641 tttttcaaat tcttttgcgg atcacttgtc tcgccaacgg ttaagccgat catttcaatt
    71701 ccagcaaaac tgaataaaac cataggaaat gagactacca ttccagcaaa gccaaacggt
    71761 agtaattcat cgatctgtcc aaaattttct ttgattccga tagactgggt atgaaaatct
    71821 gagacactca atcctatacc caataagata aaaaggaaaa tccccaagat cttgatgatt
    71881 gagaaaaaag attccaattc accaaaccac ttgactgcaa caaggttgac tgccattaag
    71941 atcattagtg cgctacctcc gcttatcaaa gctggtacat gtacaaacca gaaatggata
    72001 tacaatccta ttgctgttaa ttccgcaagt ccagctccaa gccagcaaag ccaataagtc
    72061 caattgacaa aaaatgccca ctttttgcct aaataatagt caacgaaatc actgatagag
    72121 ttaaatgtac tatttgctaa aaataaatca cccatggccc gcatcaaacc ataaatagcc
    72181 aaaccgcata tcaaataaac gagaataaca gctggccctg ctgatgcaat tgcctttgct
    72241 gaacctaaaa ataatcctgt tccaattgcg ccacctaatg cgattaactg gatatttcga
    72301 ttagttagag tccgtttcat tgccggtttt tccatcaagt tcaccttttt ctttttcaag
    72361 cagcatggcg acttcctgtt cccaagaagg tttctttatt ttttcaatac agagtggtac
    72421 tacaaacaaa atgacactga tggctgtgac tgcaattaga ttgatccatg ttccagcttt
    72481 catcgtcagt ccgacagaaa atccgattgc cgcaaataaa acaataacga cagtccaaac
    72541 tccaagattg ctctttttct ctttttttcc aattctaaat ggtcgattca actttgcatg
    72601 tgtataacgc aatctcaaaa ctgcgatccc catgatgaca tagacgatac agtagataac
    72661 agtagttgaa tttacgagca tcaaaaatgc ttgattgacg ccaggaatca gcaaataaaa
    72721 aagtgcaaag attgagataa tgacagactg agtcaaaata acggatttgg atacgtcaaa
    72781 ttgattcgtc ttccaaaaat tgaattttgg tggatacgca ccttttctag cactttctgt
    72841 cactgtcttt gctggtcctg aggcccaagc agataattgg actgctacac caatgaagac
    72901 aagtaaacta aacagattca caataagatg tggcaaacca agaatttggc aataaatcga
    72961 aatagattgc gcgatattat tcaattccat ttgtcctttt ggtacgacat ttgctacaac
    73021 taaagcattc aaaatattga cgaaaaatat aaaaattaac gcggcaaata ctccgcgaat
    73081 atacgtttta actggatttt ccaatcgagt gatatacaca gaggacattt cgataccagt
    73141 aaaaataaac atgatcggcg caaaataaac aaatgaggat gcagtcgtag tatctggtat
    73201 taatttgtcc catgaaaaac tgcctaatgt tccggttggt acgatcccaa ctttgatcca
    73261 cgcagcaaac cctaataaga gcatcatcgt caaaggcacg tacaatccta accaaacacc
    73321 gacttttccg ccgatttttg ccatatcaaa tttcaaattc aaaaaagtga tgatccaata
    73381 aacgactaaa atgacaacta atgtaaattt gctgttcaaa ccaagcggca cattatcgat
    73441 aatattacca aacaacggag cgagtgctga agcgaccatc accatcccag gaaacatttg
    73501 gacccataac agccatgaga caacgaaccc ccattttttt cctagagcat tcgataccca
    73561 aagttctgga ccaccttttt ggggaaacat tccagcaaat tcaccagaga tcaatgagat
    73621 tggaaaagcg tacaataata ctgcaaccag catgtaaaaa atcatcgtcc agctcgttgc
    73681 tgctacatct ggaatatttc gtacacttgc tacaagggcg caggtcattc cgataaaggt
    73741 catggtcgtg atttgctttg atgaaccagt atctttcatc tttattcctt ctttcaatag
    73801 cgacatatgt ttttgttttc ttttattttt gttcaagaac agaaatgaca aggtttcatc
    73861 gattcagtac aaaacccagt atcaccgaaa catccattga acgatcttag tgaactgggt
    73921 ttgatacatg aaacgaacga tccaacttat agaacgtttt ataaaaaaga atatcttggc
    73981 gaggaatata tgaaaaacag ggggaaatac aattgttttg atgaagcaaa taattgtctg
    74041 ttctccatat gtctcttgtt attctttcac acaaaaatca gttctattgg atgatttcgt
    74101 ttagtttctt ttccattgct ttggcgattt tttttgtata aaaattgaaa attcgatcat
    74161 cattcaaata aggagtcatg atagccgcac gtagcagagt gattttctgt tcttttttcc
    74221 attcttcttt cgttagaccc attctttcaa caaaacgaat cggagaatca ccgtaatctt
    74281 cttgtgtaaa tgtagtatga gaagtaataa accgttcacc ataaacatcg ccatccatat
    74341 aagaagaccg atcgaacatt ttttcattta attcattgat agcgttcaaa tctgtacagc
    74401 cttgttcttt gaatacccaa ttgaccatat taaaatcagg atgattcaat ggatagactt
    74461 cgattgtttt tcctttaaca gtaaaagtca gatgatcgag aaattctctg aatctttgag
    74521 ctgcctcgat tgaagcccca atcaattgac catatccggt cacattcaat ggcaatacac
    74581 gatgtgctgt ccagactgcg gcggcggttg ctccagcttt tgatccttcc aaaatataag
    74641 ctcctaacat atctggagcc tttactgatt tttcaaacac atatggcgcg aaataagaaa
    74701 tgatatttct catattttta tgtttgatta cgattcctcc agcagcataa gggacatagc
    74761 ccatcttatg aggatctatc gtgacagaat ccgcttctga aatagctctg aacccttcat
    74821 atacctcttt gtcaatcgtt acgcagtggt ggaaaacatg atgttcttca aagaattcag
    74881 ctaaggaagc atacggcaca aattctcctg cttcgtttag aaacagtgaa cgcgcatagc
    74941 cgccatatgc ggcatcaaca tgtaaataga aatagatccc ttcatctttt aacctttctc
    75001 ttaattggac gattttatct acactgtcta cttgaccttc ttctgtcgtt cctacgacag
    75061 caaccacacc tagaattggg attttttgtc cagctaattc acgaattgtt ttttccaaag
    75121 cattaatatc cattcgataa tcctcttgaa ctgggatagc aaccatctga tctaagccga
    75181 ctccgcaaat atctaacgcc ttcatccaag aatagtgttt tgtttgaggg accagccatt
    75241 tccctaatct ttggatattt tttccgctac gggaagaagc tgctttgacc tcatccattt
    75301 cttcgtccgt aaagctttcg gtcatttcca aaatttcttc aacagataaa ttcaaaagtt
    75361 cccactcaga catttttttc actttttcag gcagcacttc cttgacagct aaaggaatcg
    75421 atttgatgca acgggcgtac cataatcctt caagattagc aatagaacca tctgctgcaa
    75481 tgtgtcccca tccgtctgtc atattgaata atgaagcaaa atcctgtcct acttctgctt
    75541 ccatttgcga agttgccata gaagattcca atgcaacatt atttgggttc cacagcatcg
    75601 catagttgta agctaataaa gcaggcatca atgtttcagc attcatttgt ccccagtaac
    75661 ggcctgctga atgccatggg atcgatcctg cgcgtaatcg ctgactgact tcatccaaga
    75721 cctctatcat atggtcgcgg gtggctagat aatctggagt gagcttatct ccttcgctaa
    75781 ttgcaggcat atctgaagga atataatttt ctctccatcc aagatgttca tctaccatct
    75841 tgttcaacaa cattttataa actggtccat tttcagcttt gtcgcctata aagacggcct
    75901 tgatatccat atctttcatt tttcttccct ccatattttg ttggtcaatg tcttgcagat
    75961 acatgtgttt atctgtaaca cctcttcact atagcgccaa aaatgagaat ttttttttta
    76021 taacatcaaa tccacgtaga tttttacaaa caaaaataaa taaagtcgga tttttctgat
    76081 aattcaacgc aaaaaagcga acaatttttc aataaatcag tcttctaaaa tagataacct
    76141 aaaaaaagcg aacaaacaaa taaaatgact gt
//
LOCUS       DACCVZ010000003        73327 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.003, whole genome shotgun sequence.
ACCESSION   DACCVZ010000003 DACCVZ010000000
VERSION     DACCVZ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 73327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73327
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.003"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(90..1649)
                     /locus_tag="IVW63_000172"
     CDS             complement(90..1649)
                     /locus_tag="IVW63_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HAP7858476.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            1804..4038
                     /gene="pcrA"
                     /locus_tag="IVW63_000173"
     CDS             1804..4038
                     /gene="pcrA"
                     /locus_tag="IVW63_000173"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HAP7858477.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            4055..6091
                     /gene="ligA"
                     /locus_tag="IVW63_000174"
     CDS             4055..6091
                     /gene="ligA"
                     /locus_tag="IVW63_000174"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAP7858478.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            6197..6502
                     /gene="gatC"
                     /locus_tag="IVW63_000175"
     CDS             6197..6502
                     /gene="gatC"
                     /locus_tag="IVW63_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HAP7858479.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            6502..7974
                     /gene="gatA"
                     /locus_tag="IVW63_000176"
     CDS             6502..7974
                     /gene="gatA"
                     /locus_tag="IVW63_000176"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HAP7858480.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            7971..9401
                     /gene="gatB"
                     /locus_tag="IVW63_000177"
     CDS             7971..9401
                     /gene="gatB"
                     /locus_tag="IVW63_000177"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HAP7858481.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            9411..10466
                     /locus_tag="IVW63_000178"
     CDS             9411..10466
                     /locus_tag="IVW63_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAP7858482.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            10577..11950
                     /gene="rlmD"
                     /locus_tag="IVW63_000179"
     CDS             10577..11950
                     /gene="rlmD"
                     /locus_tag="IVW63_000179"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAP7858483.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            11953..12081
                     /locus_tag="IVW63_000180"
     CDS             11953..12081
                     /locus_tag="IVW63_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAP7858484.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            12521..12709
                     /locus_tag="IVW63_000181"
     CDS             12521..12709
                     /locus_tag="IVW63_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAP7858485.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            12787..13800
                     /locus_tag="IVW63_000182"
     CDS             12787..13800
                     /locus_tag="IVW63_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP7858486.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(13867..14901)
                     /locus_tag="IVW63_000183"
     CDS             complement(13867..14901)
                     /locus_tag="IVW63_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7858487.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            15016..17241
                     /locus_tag="IVW63_000184"
     CDS             15016..17241
                     /locus_tag="IVW63_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP7858488.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            17259..19142
                     /locus_tag="IVW63_000185"
     CDS             17259..19142
                     /locus_tag="IVW63_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HAP7858489.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            19123..20097
                     /locus_tag="IVW63_000186"
     CDS             19123..20097
                     /locus_tag="IVW63_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HAP7858490.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            20756..21778
                     /gene="aroF"
                     /locus_tag="IVW63_000187"
     CDS             20756..21778
                     /gene="aroF"
                     /locus_tag="IVW63_000187"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAP7858491.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            21811..22875
                     /gene="aroB"
                     /locus_tag="IVW63_000188"
     CDS             21811..22875
                     /gene="aroB"
                     /locus_tag="IVW63_000188"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAP7858492.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            22877..24043
                     /gene="aroC"
                     /locus_tag="IVW63_000189"
     CDS             22877..24043
                     /gene="aroC"
                     /locus_tag="IVW63_000189"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAP7858493.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            24060..25151
                     /locus_tag="IVW63_000190"
     CDS             24060..25151
                     /locus_tag="IVW63_000190"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAP7858494.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            25164..26459
                     /gene="aroA"
                     /locus_tag="IVW63_000191"
     CDS             25164..26459
                     /gene="aroA"
                     /locus_tag="IVW63_000191"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAP7858495.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            26452..26961
                     /locus_tag="IVW63_000192"
     CDS             26452..26961
                     /locus_tag="IVW63_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAP7858496.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            26958..27794
                     /gene="pheA"
                     /locus_tag="IVW63_000193"
     CDS             26958..27794
                     /gene="pheA"
                     /locus_tag="IVW63_000193"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAP7858497.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(27857..29593)
                     /locus_tag="IVW63_000194"
     CDS             complement(27857..29593)
                     /locus_tag="IVW63_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP7858498.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(29590..30519)
                     /locus_tag="IVW63_000195"
     CDS             complement(29590..30519)
                     /locus_tag="IVW63_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7858499.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            complement(30519..31097)
                     /locus_tag="IVW63_000196"
     CDS             complement(30519..31097)
                     /locus_tag="IVW63_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP7858500.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            31370..32656
                     /locus_tag="IVW63_000197"
     CDS             31370..32656
                     /locus_tag="IVW63_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7858501.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            32793..33662
                     /locus_tag="IVW63_000198"
     CDS             32793..33662
                     /locus_tag="IVW63_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7858502.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            33659..34546
                     /locus_tag="IVW63_000199"
     CDS             33659..34546
                     /locus_tag="IVW63_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7858503.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            34713..35396
                     /locus_tag="IVW63_000200"
     CDS             34713..35396
                     /locus_tag="IVW63_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAP7858504.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            35393..36166
                     /locus_tag="IVW63_000201"
     CDS             35393..36166
                     /locus_tag="IVW63_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAP7858505.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            36163..36561
                     /locus_tag="IVW63_000202"
     CDS             36163..36561
                     /locus_tag="IVW63_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HAP7858506.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            36746..37417
                     /locus_tag="IVW63_000203"
     CDS             36746..37417
                     /locus_tag="IVW63_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858507.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            37476..37916
                     /locus_tag="IVW63_000204"
     CDS             37476..37916
                     /locus_tag="IVW63_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858508.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            37928..38596
                     /locus_tag="IVW63_000205"
     CDS             37928..38596
                     /locus_tag="IVW63_000205"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAP7858509.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            38660..39283
                     /locus_tag="IVW63_000206"
     CDS             38660..39283
                     /locus_tag="IVW63_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAP7858510.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            39339..39725
                     /locus_tag="IVW63_000207"
     CDS             39339..39725
                     /locus_tag="IVW63_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HAP7858511.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            39938..41329
                     /locus_tag="IVW63_000208"
     CDS             39938..41329
                     /locus_tag="IVW63_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAP7858512.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            41940..42308
                     /locus_tag="IVW63_000209"
     CDS             41940..42308
                     /locus_tag="IVW63_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAP7858513.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            42488..43429
                     /locus_tag="IVW63_000210"
     CDS             42488..43429
                     /locus_tag="IVW63_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAP7858514.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            43498..44229
                     /locus_tag="IVW63_000211"
     CDS             43498..44229
                     /locus_tag="IVW63_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAP7858515.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            44373..46553
                     /locus_tag="IVW63_000212"
     CDS             44373..46553
                     /locus_tag="IVW63_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAP7858516.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            46573..47055
                     /locus_tag="IVW63_000213"
     CDS             46573..47055
                     /locus_tag="IVW63_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAP7858517.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            47071..47832
                     /locus_tag="IVW63_000214"
     CDS             47071..47832
                     /locus_tag="IVW63_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAP7858518.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            47963..49297
                     /locus_tag="IVW63_000215"
     CDS             47963..49297
                     /locus_tag="IVW63_000215"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAP7858519.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            49604..50089
                     /locus_tag="IVW63_000216"
     CDS             49604..50089
                     /locus_tag="IVW63_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HAP7858520.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            50082..50765
                     /locus_tag="IVW63_000217"
     CDS             50082..50765
                     /locus_tag="IVW63_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAP7858521.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            50891..53536
                     /gene="polA"
                     /locus_tag="IVW63_000218"
     CDS             50891..53536
                     /gene="polA"
                     /locus_tag="IVW63_000218"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAP7858522.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            53581..54417
                     /gene="mutM"
                     /locus_tag="IVW63_000219"
     CDS             53581..54417
                     /gene="mutM"
                     /locus_tag="IVW63_000219"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAP7858523.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            54381..55010
                     /locus_tag="IVW63_000220"
     CDS             54381..55010
                     /locus_tag="IVW63_000220"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAP7858524.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            55062..55394
                     /locus_tag="IVW63_000221"
     CDS             55062..55394
                     /locus_tag="IVW63_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAP7858525.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            55706..56197
                     /gene="nrdR"
                     /locus_tag="IVW63_000222"
     CDS             55706..56197
                     /gene="nrdR"
                     /locus_tag="IVW63_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAP7858526.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            56220..57593
                     /locus_tag="IVW63_000223"
     CDS             56220..57593
                     /locus_tag="IVW63_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiation and membrane attachment"
                     /protein_id="HAP7858527.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            57593..58519
                     /gene="dnaI"
                     /locus_tag="IVW63_000224"
     CDS             57593..58519
                     /gene="dnaI"
                     /locus_tag="IVW63_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HAP7858528.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            58648..59088
                     /locus_tag="IVW63_000225"
     CDS             58648..59088
                     /locus_tag="IVW63_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAP7858529.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            59232..59933
                     /locus_tag="IVW63_000226"
     CDS             59232..59933
                     /locus_tag="IVW63_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HAP7858530.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            59930..61051
                     /locus_tag="IVW63_000227"
     CDS             59930..61051
                     /locus_tag="IVW63_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAP7858531.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            61066..62298
                     /gene="pepT"
                     /locus_tag="IVW63_000228"
     CDS             61066..62298
                     /gene="pepT"
                     /locus_tag="IVW63_000228"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAP7858532.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            62430..63338
                     /locus_tag="IVW63_000229"
     CDS             62430..63338
                     /locus_tag="IVW63_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAP7858533.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            63373..63645
                     /locus_tag="IVW63_000230"
     CDS             63373..63645
                     /locus_tag="IVW63_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAP7858534.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            63656..64702
                     /locus_tag="IVW63_000231"
     CDS             63656..64702
                     /locus_tag="IVW63_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAP7858535.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            64953..67562
                     /gene="clpB"
                     /locus_tag="IVW63_000232"
     CDS             64953..67562
                     /gene="clpB"
                     /locus_tag="IVW63_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAP7858536.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(67713..68384)
                     /locus_tag="IVW63_000233"
     CDS             complement(67713..68384)
                     /locus_tag="IVW63_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858537.1"
                     /translation="MIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGITFIVES
                     LLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWDKILHA
                     VSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLCDQFLG
                     MNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFESYKLE
                     KVKNT"
     gene            complement(68377..68871)
                     /locus_tag="IVW63_000234"
     CDS             complement(68377..68871)
                     /locus_tag="IVW63_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAP7858538.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(68891..70111)
                     /locus_tag="IVW63_000235"
     CDS             complement(68891..70111)
                     /locus_tag="IVW63_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7858539.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            70258..72093
                     /gene="lepA"
                     /locus_tag="IVW63_000236"
     CDS             70258..72093
                     /gene="lepA"
                     /locus_tag="IVW63_000236"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAP7858540.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(72187..73314)
                     /locus_tag="IVW63_000237"
     CDS             complement(72187..73314)
                     /locus_tag="IVW63_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7858541.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNTVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT        24160 a        13110 c        15797 g        20260 t
ORIGIN      
        1 gttttcccag cctcttcttt ttttatagaa tcatatagaa tcaagtagtg tagatgaata
       61 gttgttgtaa aatagttttt ccatgttcgt taaaatgatt gcttcaaatt tgtgatagaa
      121 gatttagcct cgatttcctg cttgattctt ggcaagtttg cttcatcagt caagataacc
      181 aaaatatctc ctacattcat gatcgtatca ccgtgagtca agatttcctg atttcctctg
      241 cgtatagaga ttagcagcat atttttaggc caattgaagt ctcgtaccat taatccgtct
      301 aaagaactct ctgccgttac tggaaaatca aaagttgtcc ttgcaccttt tagtgaggcg
      361 gtctgagtat ttccaagtag acgttccaat aatgattcgt aaattggatt accgccgaga
      421 aggtcattga cgatataagc aacaagagca gccaatccta aaggcatcag atgattaaga
      481 gagccaacca tttctgtcac taaaataatt gctgtcagcg gtgcttttcc aatcgctgtg
      541 aaataaccag ccatggcaat aacgacaaaa tccttgatgt agattggatc catcccgaaa
      601 tcaaccataa tgtttccata aaagctaccg attaaagccc ccaatgtcaa tatcggaagg
      661 aaaatccccc ctggaagacc cccaccgtaa gaaatcatgg aaaaaacgaa tcgaagaaca
      721 aacaaaccga taatcataat gattggcaag gaagcatgtc caaaagctaa aacgatttga
      781 ttgcctccgc ctagagtact aggccataaa taaccaattg gcaaaatcag caagaaagga
      841 acgaacccgt gaaaataagc tggtaaaggc aatcggttgt aaaattttgg caaagccagc
      901 aagacattct gataaataaa acctaagatg cctagaagta ctcctaagat cactaaggaa
      961 ccataatatt tcaacggcaa agaaggaagg tcacctagat ataaaacagg tctcaagccg
     1021 aaaaagtaaa gagagacgaa gttagcagtg attgctgaag caaatgatgt cagccaaaca
     1081 agtggagaaa aggagtgatg gatttcttct aaaacaaaga gtaatcctgc gataggagca
     1141 ttgaatgctg ctgcaagtcc gctacttgca ccgctagaaa ttaaaatctt ttcttctgaa
     1201 gatggactcc gaaacaattg tccagctcct tgtccaatgg atgcgccaag ctgtatagaa
     1261 ggtccttctc tacctagaaa aaggcccgca ccaactgaaa gtacaccgcc aatgaacttt
     1321 ttccataaaa cagagaacca gttcattgat aattccccgc gaagctgtcc ctctacttgt
     1381 ggaatcccgc ttcccttgat atccggttca tttttgacca gataacccac gaaaaatgct
     1441 gcaaggatgc agcaaatagc taggccaatt aagtaaatcg gctgttcccg actcatttca
     1501 tagatacttc gaactaaatc gcttagcttt tcgatagata atcgaaacag gctaacgacg
     1561 attcctgtca gcagtccaac aaatattcct tttagaataa aatatatctg agtcttatct
     1621 aatttcttga tttttccttt tttttccatt caaacgcctc gctttctttt aatttagcgc
     1681 gaaatcaacg aattgacaag gaaaaatcca taaaaagaaa caaatgattt tgaactagct
     1741 agtttaatga aagccaagaa aatgctataa ttaacaagat tgataaaaga aaggatgttg
     1801 ttaatgtcat ccaaagctga attattaaac gggatgaacc cccgtcagaa agaagctgtt
     1861 cttcacactg acggaccatt actgctaatg gcaggtgcag gaagtggaaa gacgagagtg
     1921 ctgacacacc gcattgccta tttgattgag gaaaaagaag tcaatccttg gaacatccta
     1981 gcgattactt ttaccaataa ggctgcaaaa gaaatgaaag aacgtgtcaa tgcgattctc
     2041 gcatctggag gcgaagatgt ctgggtatcg acttttcact cgatgtgtgt gcgtatttta
     2101 agaagagatg ttgattttat cgggtataac cggaacttta caatcatcga ttcttctgaa
     2161 cagctgacct tgatgaaacg gatactaaaa gaactgaaca ttgatccgaa aaaatatgat
     2221 cctcgaagta tattaggaac aatctctcaa gcaaaaaaca gcctgcagac ccctcaggat
     2281 tttgcaaaaa tgcaaggcag ttattacgaa gagattgcgg caaaatgtta tgctgcttac
     2341 caaaaagagc ttcaatataa tcaatgtatg gactttgacg acctgatcat gaatacgatt
     2401 cgattatttg aagaacatcc tgattcactc acgtattatc aaaacaaatt ccattatatt
     2461 catgtagatg agtaccaaga tacaaatcac gcacagtata cgctagtcaa tttattggca
     2521 ggtagattta ggaacctgtg cgtcgtggga gatgcagatc aaagtattta cggctggcgc
     2581 ggtgcagata tgcagaacat cttggatttt gaaaaagatt atccagatgc tgcagtaatt
     2641 ttgctagaac aaaactatcg ctccacgaaa aacatcctta gcgcagcaaa ccaagtcatt
     2701 gaaaacaata gcaatcgaaa accaaaaaac ttgtggacag aaaacaaaga aggaaacaag
     2761 atcacttact accgtgcaga taatgaacga gacgaaaccc gttttatcgt agaccggatg
     2821 caagaagaga ttcgaagcaa tcatcggaat tacggcgact ttgccatctt gtaccggacg
     2881 aacgcacaat ctcgtgtaat ggaagaaact ctgttgaaag caaatattcc ttataaaatg
     2941 gttggagggc acaagttcta cgatcgtaaa gaaatcaaag atattttagc gtatttgaat
     3001 gtgctggtaa atcctcaaga ttcaatcagt tttgagcgta tcgttaattc gcccaaacga
     3061 ggcatcggac caggatctat cgaaaaacta cgcagttttg cttctcttca tgaatggcca
     3121 ctgcttgaag cagcgcaaaa tgtggatctg gcaaatatcg gtggaaaagc aggacagcaa
     3181 ttaggtgcat ttggagagat gatccaagaa gtcactcaga tgatcccata cttgacagtg
     3241 acagaattga cgaaagaggt tttggatcgt agcggatatc tagaagactt aaaaatccaa
     3301 aatacattag aagcacaagc acgcatcgaa aacttggagg aatttttaac ggtcacacaa
     3361 gaattcgaca aacaattcga acagcaaaat gaagaagacg ctgatgcacc agaagaaaaa
     3421 ctaacggtct tcttaaatga tctggcactt gtttccgaca ttgacaattt agaagaagat
     3481 gcttcccaag tgacattgat gactttgcat gcagccaaag gattagaatt tccagttgta
     3541 ttcctgattg gtctagaaga gggggttttt cctttatctc gagcattgat ggaagaaagc
     3601 gaactggagg aagaacgccg tctcgcatat gtggggatca cgcgagcaga agaagcgttg
     3661 tatttaacaa atgctttctc cagaacatta tatggacgga cgcaatataa ccgaccttct
     3721 cgttttgtag aagaaatcga tcaggagtta ctggaaatcg aaggcatgcg tcctacgcct
     3781 aaaaaaacgc ctgtattcgc taaaaaaaca gcatatagct ataaacagcc agagacagcg
     3841 gttgttccct ctaaaagtgc tactggaggg gaaaataaca gctggaaacc tggagataaa
     3901 gtcaaacaca aaaaatgggg tctaggaaca gtcgtccgag taagcgggac gtcgaaggat
     3961 ctagaactag atgtggcttt cccaagtcaa ggagtaaaac gtcttttggc tgcctttgcg
     4021 ccaattgaaa aagcttagta gtggagggta aatgatggaa catgaaatga cgattgacga
     4081 agctgctaaa cgagcagaag aacttcgtac aagactgaac caatggtctc gcgaatacta
     4141 cgtagaagat aaaccaacag tggaagacta tgtttatgat aaagaatacg cagaattagt
     4201 agcaatcgag gaacaatatc ctgatttgat cacgtctgat tctcccactc aacgagtagg
     4261 cggaaaagta ttagaaggtt ttgaaaaagt cactcatgat attccgcttt acagtttgaa
     4321 cgacgttttc agcaaagaag agctgatagc ttttgatcaa cgtgtacaaa aagcagtggg
     4381 acgtgtagtt gactattgct gtgaactaaa aatagatgga ctttccgttt ctttgcgtta
     4441 tgaagatgga aatttcgtga gaggtgcgac tcgcggggat ggaactgtag gagaaaacat
     4501 cactgaaaac ctaaaaactg tccggtcggt cccaatcaaa ttaaaagaac caatgaacat
     4561 cgaagtaaga ggcgaatgtt tcatgccaaa acggtcattt gtccaattga accaagacag
     4621 agaagcagag ggaaaagata tctttgcgaa tcctcggaac gccgcagctg gttctttgcg
     4681 tcagttagat tctaaaatca cagcgaaaag aaatctggac acttttttat acacagtagc
     4741 tgatttcggt cctatgcaag caaaaaccca gtatgatgcg ctagaagagc tagaaaaaat
     4801 tggattccac acgaatcggg aaaaacgtct atgtcattcg attgatgaag tgtggtcata
     4861 cattgaagaa tatcatgaca aacgtgtgga tttgccctat gaaatcgatg gaatcgtcat
     4921 caaagtgaat gaattctcgc tacaagatca acttggtttt actatcaaag caccgagatg
     4981 ggcagcagct tacaagtttc cgccagaaga agttgaaacg ctaatcgaaa acatcgaatg
     5041 gacagtcggt cgaacagggg tagtaacgcc aacagctatc atgacaccag tccgagtagc
     5101 aggaacgaca gtaagccgtg ccagcctgca taacggtgat tatattaagt tgaaggatat
     5161 ccgcttgaaa gatacagttc tgatttataa agcgggagac atcatcccag aagtttcgca
     5221 agtcgtgtta gataaacgac ctaaagacag cgaagaatac caattgccta cacattgtcc
     5281 agtttgtgga agtgaacttg tccatttgga tgaagaagta gccttacggt gcatcaatcc
     5341 taaatgccct gctcaaatga aagaaggttt gaaccacttt gtttcaagaa atgcgatgaa
     5401 tatcgatggg ttggggccgc gcgtactaga acagatgtat gataaaaaac tagtagcaga
     5461 tgttgctgat ctttacaaat tgacagaaga agagttattg acgttggaca aaataaaaga
     5521 aaaatcagca aataatattt tgacagcaat cgacaacagc aaagataatt cggtcgagcg
     5581 gttgattttc gggttaggaa tccgacatgt cggagcgaaa gcagcaaaaa ttttagcaga
     5641 acatttcggt gatctagaaa cattgagtaa aagtgactat gagtcgatta ttgcgcttga
     5701 tacgatcggt gatatcattg ccgacagtgt agtcacttat ttcagtaacg aagaagtcca
     5761 tgaattgatg aatgaattaa aacaagcagg cgtcaatttc gaatacaaag ggcttcgaaa
     5821 tgcccaattg caagaagtcg agtctccttt taaagaaaaa acagtagtcc ttactggtaa
     5881 actaacacga tttactcgtg aagaagcaaa agagacgatc gaaaatcttg gcgggaaagt
     5941 gactggtagc gtatcgaaaa aaacggatat cgtggtagca ggagaagatg ctggcagcaa
     6001 gctgaccaaa gcacaagaat taggaatcga agtttggaca gaagatcaaa tggcagatgc
     6061 attggctaaa agtcgctcag tagaagaatg aaaaatgagt tttttcagac aaatttcaat
     6121 aaacaatttc agacacggca ctcttgtgtt aaaatagaga gcaaagtttt taactcgttt
     6181 agaaagaagg ggtagtatgg cgattagtga agaacaagtg aaacacgttg ccaaattagc
     6241 aaaacttgcg ttcgcagatg aagaacttgc aagttttacc gaccaattag gtaaaatcat
     6301 cgatatggtt gaaatgctgg aagaagtaga tacggaaggt gttccattta cgtcgaatgt
     6361 ggttgaaaca gtaaacgtga tgcgacaaga tcgggcgcaa gctggatgga accgcgatga
     6421 attattgaaa aatgtgccgg aaacagaaga cggctttatc aaagtacccg caatcatcga
     6481 taatggggag gctggcgcat aatgacagaa ttacacaatc gttctctaga agaactgcat
     6541 catatgcttg tatcgaaaga aatcactgta caagatttga caaaaacaac atttgaacga
     6601 atcaaagaaa cagagcctga ggtcgaggca ttcattacat tgaacgaaga aaaagcattg
     6661 gaacaggcaa aagctttaga tgaaaaaggg attgatgaaa gcaacgtcct tgctggtatt
     6721 ccaattggta tcaaggataa tatcgtaaca aaagatatct tgacaaccgc tgcatctaag
     6781 atcctttaca attttgaacc aatttatgat gcaacggtca tggataaaat ctatcaagca
     6841 gatatgatcc ctgttggtaa gctaaacatg gatgaatttg ctatgggtgg aagtacagaa
     6901 acttcttatt tcaagaaaac aaaaaatgct tgggacccaa caaaagtacc tggtggctct
     6961 tctggtggtt ctgcagcagc agttgcagct ggacaaattc cagtttcttt aggtagtgat
     7021 actgggggaa gtatccgcca accagcagct tttaacggca tcgtagggat gaaacctact
     7081 tatggccgtg tctcacgttt tggtttgatt gcctttgctt catctcttga ccaaatcgga
     7141 ccaatgaccc gtacggtgaa agataatgca ttagcattga cagctatcag cggttatgac
     7201 gaaaaagacg gtacttcttc aggcgtttca gttcctgatt ttgcagaggg actgacaggc
     7261 gacatcaaag gaatgaagat tgctttacct aaagaatact taggcgaagg tgtggcccct
     7321 ggcgtaaaag aagctgtatt gaaagcagca gaaacattcc gttcattagg tgctgttgtg
     7381 gaagaagtca gcttgcctca ttcaaaatac ggtgtggctg tttattatat cattgcctca
     7441 tcagaagcaa gttccaattt gcaacgattc gatggtatcc gctacggtta tcgctctgaa
     7501 aatgtgaaat cattagatga tgtatatgtc aactcacgtt cagaaggatt cggtgaagaa
     7561 gtaaaacgcc gtatcatgtt aggtacattc tccttaagcg cgggttatta tgacgcttac
     7621 ttcaaaaaag caggacaagt ccgtacattg atcaaacgag attttgaaaa agtctttgca
     7681 gattatgact tgatcatcgg gccatcttca ccaacagttg cattcggaat cggtgagaac
     7741 attaacgatc caatcacaat gtacatgagt gacatcttaa cgatccctgt caacttggct
     7801 ggacttccag gtatgtctgt accggcaggt ttatcagaag gattaccagt tggattgcag
     7861 atcatcggta attattttga tgaaaaaacg atgtatcaag cggcatatgc gtttgaacaa
     7921 gcaacagaat tccataaaca acaaccagct attttaggag ggaaagacga atgaattttg
     7981 aaacagtcat tggactagaa gtccacgtcg agttaaaaac caactcaaaa attttctctc
     8041 cagcgccagc tcattttggt gcagaaccaa acagcaatac aaacgtgatc gactggggtt
     8101 atccaggcgt gctgccagta atgaataaag ctgcgctgga attcgggatg aaagcagctt
     8161 tggcattaaa ctgtgaaatc tctaaagata ctcattttga ccggaaaaat tacttttacc
     8221 cagataatcc aaaagcatat caaatttccc aatttgatca accaatcggt catgacggat
     8281 ggatcgaaat cgaagtagaa ggtaaaaaga aaaaaatccg gatcgaacgt gtccatttag
     8341 aagaagatgc tggaaaaaac atgcatggta ttggcggtta ttcttacgtt gatttgaacc
     8401 gacaaggcac gcctttgatc gaaatcgttt ctgaagctga tatgcgttca ccagaagaag
     8461 catacgctta tctagaagca ttgcgatcaa ttatccaatt tacagaagtc agcgatgtga
     8521 aaatggaaga aggctctatg cgctgtgatg ccaatatttc tcttcgccct tatggacaag
     8581 aagagttcgg tacgaaagca gaattgaaaa acttgaactc tttatctttc gtgaaaaaag
     8641 gtttagcttt tgaagaaaaa cgtcaagcaa aagttcttct ttcaggagga gaaatccaac
     8701 aagaaacacg ccgttttgac gaaacaacga ataaaacagt tttgatgcgt gtcaaagaag
     8761 ggtctagtga ttatcgttac ttcccagagc ctgatatccc gaaattcgtg atcgatgacg
     8821 aatggattca aaaagtaaaa gctagtttgc ctgagatgcc agcttctcgt cgcgaacgct
     8881 atatccgtga gtttggactt ccagagtatg acgcaatggt attgacactt acaaaagaaa
     8941 tgtctgattt ttttgaagct gttttggaaa atggtgcaga tgccaagcaa gcatctaact
     9001 ggttgatggg tgaagtttct gcttacttga acagtgagaa actggaatta gctgagacaa
     9061 aattgacacc tgagaactta gcaggaatga ttcgtttgat cgccgatgga acgatcagct
     9121 caaaaatcgc caaaaaagtc ttccgtgaat tgatcacaaa tggcggagaa gcccaagaag
     9181 tagttgaaaa aaatggttgg gtgcaattat ctgatccgaa caaactactg ccaatcatta
     9241 atgaaatttt ggataacaac caacaatctg tcgatgattt caaaaatgga aaagatcgtg
     9301 cggttggctt cctagtcggt caaatcatga aagcaactaa aggacaagca aatcctggtg
     9361 tcgtgaataa gctacttaaa gatgaattag cgaaacgata gaggctgaaa atgaaaaaag
     9421 cacgcgtaat ttataacccc acctcgggaa aagaattatt gaaaaaaaat ttggcggata
     9481 tcctacaggc attagaagaa gcaggatttg aagccagcgc ctatgcaact acaccagaac
     9541 cagattcagc caagaatgaa gcatgtagag tcgcagaact aggttttgat ctagtagtgg
     9601 cagctggtgg cgatggcaca atcaacgaag tggttaatgg aatcgctccg cttgaacacc
     9661 gtcctaaaat ggccatcatc ccagctggta caacgaacga ctatgctcga gcattaaaaa
     9721 ttcctagaga taatattaaa gcagcagcag aagtgataaa aaaacaccaa accgtaaaaa
     9781 tggacatcgg cctttctgat aacagttact tcatcaatat cgctgcaggt ggctatttga
     9841 cagaattgac ttatgaagtt ccatcagaac taaagagtat ttttggttat cttgcttatc
     9901 ttgcgaaagg agcagagatg ctccctcgag taaagccaat caaaatgcgc ttgaagtatg
     9961 atgaagggga atatatcgga aatgcttcga tgtttttcct agggctgacg aactctgttg
    10021 gaggattcga acagatcgcg ccagatgcca aattggatga tgggaagttt tctttaatca
    10081 ttgtgaagac agcaaatatc tttgagatct tgcatattgc agcactcatg ctgaatggcg
    10141 gtcgacatgt cgatgatcca agaataatct ataccaaaac aagcagtttg ttcgttgaaa
    10201 cagaagatga tatcaatcga ccagtaatga tcaacttaga tggtgaatac ggcggggaag
    10261 caccgatgca tttccaaaat cttcatcaac acattgagtt ctttgccaat accgatcaga
    10321 ttcctgatga agcaatcaca ggtacagatg aagaagaatt agaggttgtc agcaaagaat
    10381 tcgtaaaaga agtcgaacgt ttaacggatg aagatatcga cggtgacgga aaaatagcag
    10441 acgaaacacc taatcaaaag aattaatcaa aagccggtgc tgaacgtagt aaggtcagtg
    10501 ccggttttag ttgtgtaatt agctgattta tagtagagtt cagtaggatt gaaaaatagg
    10561 cttaaaggag caaaatatga cagaacagca aatagtaaag aaaaacgaac gatatacagt
    10621 cgaaatcgtc gacttgagtt atgaaggaat gggggtagca aaaatcgatg gttatccatt
    10681 atttatcgaa aatgcactcc ctggagaaga agtagaaata ctagtagtaa aagcaggcaa
    10741 taagtttgga tatggaaaag tcgaaacatt tattacacaa tcacctgatc gtcagcctgt
    10801 agaaaacaat gcattacttc gcataggtat cgcaccttta gcccatttga agtatgaaca
    10861 acagcttgtc ttcaaacaaa aacaagtaga gcatgtaatg gcgaagattg ctaagatgcc
    10921 agaagttcct gtacttccaa cggtcggaat ggcagaacca ttcggctacc gtaataaagc
    10981 acagatccct gttcgccgta tcgatggaca gttagccacc ggtttttaca aaaagaatag
    11041 ccatgatcta gtccctatcg aagattttta tatccaagat cctgtcatcg atcaagcaat
    11101 caaagtagtc agagatatct tgcaacggtt ccaagtacga ggatataatg aagaaaaaaa
    11161 tgaaggacag cttcgtcaca tcattatccg tcgtggtcat tattcccatg aaatgatggt
    11221 cgttttagtt actcgtaaag aaaaattctt taaatccaag gaaattgctg aagctattca
    11281 tgaagaattg ccagaagtgg tttcggtcat ccaaaatatc aatgaagaaa aaacaaatgt
    11341 gattttagga gacaaagaaa aagttttata tggcagagac tatatcgaag atcagctatt
    11401 aggaaaaacc tatcgaatct cagcaaagtc attttatcaa gtaaatactc aacaagcaga
    11461 gtatctgtac caaacagcca tcgagtttgc cgagttagat aaaaaagaca ttgtgatcga
    11521 cgcttattca ggaataggta cgattggctt gtctttagca gacagagtgg ataaggtgta
    11581 tgggatggaa gttattccag aagcaattga agatgcacag ttcaatgctt taaataataa
    11641 aatcgaaaat gttcattatg aagtcggaaa agcagaaaaa gttatgaaaa aatggcaaga
    11701 aaaagggatc aaaccatctg tgatcgtagt tgaccctcca cgaaaaggat tagatcatca
    11761 ttttattgaa tcagcaatcg aaatgtcacc agaacgaatc gtctatatct catgtaatcc
    11821 ggcaactttt gcaagagatg ctaagttatt tgcagaagca ggttatgccg tgaagaaagt
    11881 tcagcctgta gatcttttcc cgcaaaccca tcatatcgaa ttagtcgctt cattcgttaa
    11941 aggagaataa aaatggacca aaaagaaaaa atgaaagaat tgatcaaaaa gaaacaaggt
    12001 ggaggccgat ccaaacaaat ggaaacacct aagaatgatc gtaaaaacat gagaaaaggc
    12061 cctaaaatct ttaataaata gacgtgctaa agaaagacta agaagtgtta acttttgtta
    12121 ttgtttctta gtctttttag ttagtctaca ttattttggc gatttgccaa taaggactgt
    12181 tgagttgtgc aaaatcaaat ctgggtcaga atgaacgtca ttctgtctca gatttttcgt
    12241 tatttcaatt tgattaactg attgatcaaa aagattttta ttttcatatt ctcaaatgat
    12301 tcaacactaa atatacatgt ttgacgcgga aattattatt cgattttggc ggcatcaggg
    12361 gggatgacga cgtagcagac ccattatttt actcaagaaa atgtccgtgc ctattattta
    12421 gaatacgata gtgaacgtgc tgggagtttt gttcttttag agaaagtctc tgaagataaa
    12481 ttagttgtct tagattttga ctgtaacgaa aaatggcgaa atggaagagc accagcaagt
    12541 gattgaccgg atctacgaag cgacacgata tctgcctttg gatcgtttgt gcttaagtcc
    12601 tcaatgtgga tttgcttcaa cagaagaaga aaatgttttg tttgaagaac aatggaaaaa
    12661 atttcttttg tcaaaagcat tgcagaagaa gtttggggaa aatcattaaa tcatctagga
    12721 gagcttgata ggaaataaca ctatggtata atcagaatgc ttaatactaa ctactgaggg
    12781 agccttatga aaaagaaaat tcttaaattt atcggatggt tcttcggaat cattcttggg
    12841 atcgcgtttg caatctttct tgccttccag ctttccccca gacctggagc attcttgatc
    12901 aaccatatgt tttcaaatac tgttcaaatc actgataaaa aaacgttcga tcaagcagaa
    12961 aaaaacgtgg cgaaaaaaac agatttgacg tatgagtcca agtataaaga gaatacttat
    13021 gacatctact atccaaaaaa cagcaagggg cctgttcctg ttctattttg ggtacatggt
    13081 ggaggattcg tcggcggaga taaatcgggt gtcaaagaat ttgcgacaaa attagtttca
    13141 gacgccaaca tcgcagtggt tgcgatgaat tatgaattag cgcctgattc agaataccct
    13201 aatcaagttc ttcaagtgaa tgaactgatc aaagatttat tagctgaaga aaaagacgac
    13261 aaattgctag acatggaaca attatttttt ggtggagata gtgcaggttc acaaatcgca
    13321 ttgcaatatg cagctataca aacgaatgat gcgtatgcta aacaaatgaa aatcaaacag
    13381 ctacttccaa aagatagtct gaaaggaacc atttcttatt gcggacctgt tgatttgaag
    13441 ctaacagcac agcagcattc ggatgatcga tttatgaagt ttttcgtcaa aaccgttgcg
    13501 tggtcgttga ttggaacaaa agattggaaa acgagtgagc aattgaaaga agctagtgtg
    13561 gctgaccatg tttctaagga atttccgcca acgtatataa ctgacggaaa tgcatactca
    13621 ttccaggagc aaggtcaagc attagaaaat cggttgacag aattaaaggt acccgtgcaa
    13681 tccttgtttt atacagatac aaaaaaagag attacccatg aataccaatt tgattacacg
    13741 ctaaaagaat cgcaaaattg ttaccagcag acattggatt ttgtgaataa gtataagtaa
    13801 gaggttgtga aaaagccgtt tcgttttgag tatgaagaaa cgaagcggct tttcacaacc
    13861 tctctttcaa tacctttttg ttcttgggat aaaactttcc ctaacaatca atcgtgcagg
    13921 ataagtcaaa atgattggtt cgtcccgtat accgtcaatt cgctccaatg ccattcgaac
    13981 agctgcttgc ccaattgatt tcgcattgat ttgaacactg gtcaagccag gggagaggtt
    14041 tgcgattgtc tcgatattat caaagcttgc tacaacaatc tcttctccaa tttggatatt
    14101 tttttgtttc aatgcccgat agacaccaat tgccattgga tcgctcccga caagaatggc
    14161 agtaggaaga ggggattcat tttctaatag attagtcgca agtacctcac cttgtttttc
    14221 tgtccagcca cctagatgat aagacatata tttttctaag tgatgatcga tcataaaatg
    14281 ctgataggca cgcatcctct tttcatttat agaaatctgc ttcccaccga attcatccat
    14341 atcgacttta tatcccccga tataggctat tcttttatga ccattttcta agaacaattc
    14401 cagtacggtt ttagtcatcc gttcaagatc tgcatacacc atatcgacct cttgctggat
    14461 gtcagggtta tccacgacga ctatttgcat gttttgtttt aacaaggcgg taatcgattc
    14521 tttcgtaaca gtcccaacaa cgatcaccgc acctaactga tctagatctt cccattgttt
    14581 aggattatca gatagattat agattcgatt catccctaaa tgcagacgtc gagcttcttc
    14641 ttccatccct actcgcaaat gtttgtaata gatatcctgt tcttcgctcg ctttgccgat
    14701 cgtagagatc acaccaatcg aaggcattct ctttttgata tatttacgag tactgatgtc
    14761 ataatccaac gcagcagctg cctctactat ccgttgccga gtagtctgag ccacatggat
    14821 cgtctgatcg ttattcaaca cacgggaaac tgtagcagga gagacatttg cctttcgtgc
    14881 gacatctcta attccaacca tttttacaca ctcctcaaaa aaataaaaaa tttttattga
    14941 caaaattgtt tagtaaacag tatacaggaa ttataaaaaa aagtaaacgg tttccgtttt
    15001 gttgggagtg aaatgatgga tattacgcat agaaaaacag ataaaaattt catcttattt
    15061 gatgaaaaga gccgagtctt ccatttacga aatacatttc tttcttatct gataaagata
    15121 gaagaaagca atgtattggc gcatatttat tttggcaaac cagtcaagca gtacaaagac
    15181 aataaaaatt atccccgaag agatcgtgga ttttcaggaa atgttccctt aaatcctgac
    15241 cggtctctgt cgaaagatac actaccgcaa gaatactctt ctcatggcag catggacttt
    15301 cgaacgcccg catcgatcat tcagcgcaag aatggatcag acttactgga tctgagatat
    15361 gacagccatt atattacaga tgggaagcca gagatcgaag gcttgcctca aacttatgtg
    15421 atggacaagt cagaggcaca aacgttggtg atttcactta aggatagaga aacagcgatt
    15481 tatttcgatt tgttctatac catatttact gatagagcag tgatcacacg atctgtaaag
    15541 ataagaaatg aaaccggaga aacaatcaaa ctagaaaaag cggctagttt ccagctagac
    15601 tttgcccata ctaggcgatt tgatgaagtc attgctttgc caggagcaca tgtcaatgaa
    15661 agacagattt cacggcaatc tgttttatct ggaacaaaag tatttgaaag ccgtcgagga
    15721 acgagcagtc accatatgaa taactttatt gctttagttc atcatcatac gacagaaaat
    15781 actggagaag cgatcggact tcaatttgtt tattccggca accattcttt cgaacttgaa
    15841 aaagatcaga tcaatcaatt gagagtcgtc ggtgggatca acagccatcg tttttcgtgg
    15901 gaattgaatg caggccagtc ttttcaaaca cctgaaatga tcctttctta ctcaagtcag
    15961 ggattgaaca aaatgagtca gatccaccat gagttgctac gtgaaagaat cgcaagaggt
    16021 cgtcatcaat ttgctgaacg gccgattctg gtcaataact gggaagccac ttactttgac
    16081 ttcaatagtg aaaaaatcaa ggcgatcatt gatgaagcaa aggagctagg catcgaaatg
    16141 ttcgtattag atgatggctg gtttggaaaa agagatgcgg acaattcttc attaggagac
    16201 tggttcgagt atgaaggcaa gttgacaaat ggattacgtg aaatagcaga ttatgctcat
    16261 agcaaaggat tgaaatttgg tttatggttt gaacctgaaa tgatctcggt tgattctgaa
    16321 ctgtatcgaa cacatcctga ttttcttatg caggagccag gtagaatgcc ttctgcttcc
    16381 agatcacaac atgtactgga ttttacaagg ttagatgttc ggcagacgat tgagaaacaa
    16441 atgagaaaga ttttagatac gattcctctt gactacatca aatgggatat gaaccgttcg
    16501 ctttcagatg tctattcgat tacccttgac ccacagagac aaggagaagt agcgcatcgt
    16561 tatatgctcg ggctttatga actacttgaa catttgacaa ctgattatcc ggaaatctta
    16621 tgggaaggct gttctggtgg aggtggacgg tttgatgccg ggtttattta ttatatgccg
    16681 cagtcatgga caagtgataa cacggatgca gtggagcgta tgaaaatcca atatggaaca
    16741 agccttgctt atccgatttc gtccatcaca gctcatgtat cagctgtacc aaatcatcag
    16801 accgacagat ctacttcgtt gaaaacaaga ggagaaacag ctatgagcgc tgtttttggt
    16861 tatgaactgg atttgacaaa gctgtctcct gaagaaaaaa agcaagtaaa agaccaaatt
    16921 atatcctatc aaacgattcg tccggtgatc cagtatggcc attattatcg tttggcgagt
    16981 ccttttgaag aaaatattgc cgcatggatg tttgtgtctc ctaaacaaga tgaagctatt
    17041 gtgtttttag ggaggatact agcttcagct caaccagcgt tccatgaagt atatctgatg
    17101 gggttagatg atgaggcact ttatcaggaa cagacctcga agcggatatt ttcgggggcc
    17161 gaattgatga cagttggact ttacttcccc gattttcaag gtgatttcca aacagaactg
    17221 cttcatttca aaaagttatg agagagaagg aaaaaagtat gaaagcaaat ataaaatggt
    17281 tagatgatcc acaagttttt agagtgaacc aatcaaatgc acatagcgat catgtttgtt
    17341 atgcaacaag ggaagaagta gaaaccacat cctcccttaa acagtcttta aatggatcat
    17401 ggcgtttttg ttattcgcca aatccttcgg tacgaccaaa aacattttat aaaaaagatt
    17461 ttgatgcctg ttcttttgat gaaatcactg ttcctagtca tattgaatta gcaaattatg
    17521 acaagatcca ttacatcaat acgatgtatc cgtgggaggg acatgtattt cgccgtcccc
    17581 ctttcacgac aagccctgag aaagaggcgg aagggatctt ttcagctgct aaagacaatc
    17641 cggttggttc gtatttgacg acttttcgat tagaagaagg tctaaaggga aaacaaatct
    17701 cgattcattt tgctggtgta gaacaagcaa tgtttatttg gttgaatggt cattttatcg
    17761 ggtatgccga agattcgttc actccgtctg aatttgattt aacaccttat ttggaagaag
    17821 aaaatattct agctgtggag gtttacaaaa gaagtacagc tgcattcttg gaagatcagg
    17881 actttttccg attttttggg atcttcagag atgtcttctt agttgctcga ggacaaaacc
    17941 atttagaaga tctttggatc aaacctcgct tagatgacaa atgtcaaaat ggcaaacttg
    18001 aagtagattt gtcttttgag caagtagcca aaaacagtca gctgaatgta gcgatactag
    18061 atcctgatgg gaaggaaatc tatcaacagc aatatccgtt aaaagagcaa atgacgattc
    18121 gcatcgatgg atttgaaaat gtggcactgt gggggcattt tcagcccaat ttatataagc
    18181 ttgaattgga gacgatagac gaagaaaaaa gagtaacgga gtatattgac tattccttcg
    18241 gttttcgtaa aatcgaaatc aaagataaaa tcatctactt caatggaaaa cggatgatta
    18301 tcaacggggt aaatcgacat gagtggcatc cgaaaaaagg acgcgccatc actatagaag
    18361 atatggaaaa agatttggct atcataaaaa atgcaaagat caacggcgta cggacatctc
    18421 attaccccaa ccagatcact tggtattatt tatgcgacca agcaggaatc catgtgatgg
    18481 cggaaacgaa cctcgaatcc catggctcat ggcaaaaaat gggcgcattt gagccttctt
    18541 acaacgtacc aggtgcagta cctcagtggc aggcggctgt tcttgatcga gcaaaaacga
    18601 atttcgaaac attaaaaaac catccaagta ttcttttttg gtctcttgga aatgaatctt
    18661 atgcggaaga aaacattcga caaatgaacg attacttcaa aaaagtagac cccgatcgac
    18721 ttgtccatta tgaagggaat tttccaaatc cagcattcga agattcgatt tcagatgtaa
    18781 aaagctgcat gtatgcgcca ccagaagaga tcattgacta ccttgaaaat aaagcggaaa
    18841 aaccgttcat cttatgtgaa tatatgcatg acatggggaa ttcgttaggt ggaatggatt
    18901 cttacatgac gttgcttgat cgttatgaaa tgtaccaagg aggctatata tgggatttta
    18961 aagatcaggc gatccaagtg actgatccaa tcacaggcag agaagtgatg cgctatggcg
    19021 gtgactttga cgataaacca agtgactatg aattctcagg gaatgggatc gtttttgcag
    19081 atggacaaga aaaacccgcc atgcaggagg taagatatta ttatgaaaaa tacagtaaat
    19141 aaaagtcata tggatacgga aaaagttgca atcgtcttcg gcgactgtac attaggtgtc
    19201 aaatcgggga atacgcatta tattttttct tatacaagag gcggactgga atcgctcaat
    19261 aaaaacggaa aagaatggct ataccgggaa acacttccag ttttttggcg agcaacgacc
    19321 gataatgaca gaggtagcgg atttggattt aaatccggta tgtggttagg agccggattg
    19381 tatccaaaag tcaaagaaat agaagtactg gtggacaata aaaagatcga tttgccgatt
    19441 gctccagtaa ataatcaata ttcaagtaat gaatacgctg aaacggttga aatcattttt
    19501 acactggaaa tcaacacagt accaaaaacc caagtgacaa tttcctacca aatcgctgga
    19561 gagggtaaaa tgcttgtcaa tatgcattat tatggacaaa aaggattacc ggaattaccc
    19621 gcattgggtt taaggttcat tatgccaacg aaagcaaaat tttttgagta tgaaggccta
    19681 tcaggggaaa catatccgga tcggatggct ggtggtgtcg aaggtattta taaagtggca
    19741 ggactccccg tttccccata ccttgttccc caagaatgcg gcatgcatat ggaaacgaaa
    19801 tgggtagaac taacaagaaa tcaaacgttg gataatacgg ataaagatca agaagatttt
    19861 tcgttgcgat ttgaacagca ggatacgcca tttgcttttt ccgctttacc attcaaagca
    19921 gaagaactgg aacaggcaac acatatagaa gaactaccgc cagaaagacg aacggttctt
    19981 acgatttttg caaaagtaag aggagtcggg ggtatcaata gctggggagc ggatgttgag
    20041 tcaccttacc gaatcagcag cgaagaggac catgaaatcg gctttattat tcagtagcaa
    20101 tctttagatt attatttgaa aaacggagtt tacaagacaa agctgcttta ttctatatgt
    20161 catgaacaag agagtaaaaa agttctcaga tacttttgtt catgactatt ttcttcaata
    20221 aaaccaattg ttatttttct gaaaaacaaa gttaactatc agaaaattaa aaaaagtttc
    20281 ataaaaatga ttgacagtcg atttttttat gtctatacta ggtacaattc ttacatcagt
    20341 ttggagcgat tttttatgaa atctagaaaa cttacaaaac tgaatacgta ttactttagc
    20401 tattttagat aggtttgtat tcatgacttc gtgggtacaa acaaaccagg tttgtatcta
    20461 tgatggctaa agatttttaa acacgactta cagccacgta gagaaattca tctatagtgg
    20521 ctattttata tttttgcagc gctttttaag gctcgttgaa gatgttcact gtagaggcaa
    20581 tttcctacag ggacatcttt ttttgttgat tatctgggtc ataagtagga aagaaggagc
    20641 gaaaatgaga acaacaggac acggtcattt agtaggaatt aatgtaaaac caccttgaaa
    20701 aagtagagaa aatcagccaa gatagataag taaacaaaag aaagcgggaa aaacaatgat
    20761 agtaattatg aaaaaagaag caacggaaga acaaataaaa aaagtcgtcg atcatatcga
    20821 aaaagaagga ttcaaagtct caatcgatca aggaacagaa cgagtagtga ttggactaaa
    20881 aggtgatacg cgaagtttac aagaaggagc atttacacgc tatgaaggag tagaaaatgc
    20941 tgtgcgtatt ttaaacacat acaaattgac ttctcgagaa ttccatcctg gcaatacagt
    21001 cgtggatgta gacggagtaa aaattggtga cggcagtttc gtgacgatgg ctggtccttg
    21061 ttctatcgaa ggattagacc aaatcagaga atgtgcgcga atggccaaag ccgggggcgc
    21121 aaaaattctg cgaggtggtg ccttcaaacc acgtacttct ccatatgctt tccaaggttt
    21181 agaagaagaa ggattgaaat acatccgtca agcggctgat gaatttggaa tgaaagtgat
    21241 tactgaagtg atggatgaag ggcatatcga tatggtggct gagtacagcg atatcctaca
    21301 gattggcgca cgtaatatgc aaaattttaa actgctatct gctgtcggta aaacaggtaa
    21361 acctgttgga ttgaaacgtg gaatttccgg tacgatcaat gaatggctta atgctgcaga
    21421 atacattgca gtcgaagaca aatctcctgt catttttatc gaacgtggga ttcggactta
    21481 cgaaacagcg acacgtaata cgtttgattt aagtgctgtc ccattgatga aaaaattaac
    21541 tcatttccct gtgattgttg atccaagtca tggtacagga atttgggaac ttgtaccacc
    21601 aatggctcgt gcgggtgtgg caagcggagc agatggcatg atcgtagaga tccatcctga
    21661 tcctgcaaat gcttggtcag acggtcccca atcgttgaat gaaaagactt actcacgcat
    21721 gatgaaagaa gttgcgatca tgaaagaagc aatggaaaag attcagacac tcgattaatt
    21781 ccagcttttt aaaagaaaga agtgaaacga atgcttactg tacatgttga taaccaaaaa
    21841 tacgatattc atattgaaaa aggcgcacta gaacaggctg gatcatggct tcaaacgatt
    21901 tggagacctc aaaaagtagc tgtgatcact gatacaaacg ttgctccact atatgcagaa
    21961 aaaatcatgt tccaattgag acaagctaat tttgaaccag tcctttcaat cgtaccggcg
    22021 ggtgagacca gtaaatcttt agaacaagca gctgagttat acgatttttt agcagataat
    22081 gattttaccc gcagcgatgg gatacttgca cttggtggag gaatggtggg tgatctagca
    22141 gcattcgtgg cctcgacgtt catgcgtggg atccatttcg ttcaaattcc gactacgcta
    22201 cttgcacaag tagattctag tattggcggg aagacagcag tcaatacaaa caaagcgaaa
    22261 aaccttgtcg gaacatttag ccagccagct ggtgtattga ttgatcctga ggttctaaaa
    22321 actttgccgg tacgtcgttt acgagaagga atcgctgaaa tcatcaaatc agcagctata
    22381 gcagatgcaa cgctttggaa acagctgaac gagctgaaag acgaaaaaga tcttctggaa
    22441 catgctgttc caatcattac tgctacgttg gaaatcaaac gaaaagtagt ggaagaagat
    22501 gtctttgacc aaggaaatcg acttatttta aattttggtc atacaattgg ccatgcaatt
    22561 gaaaatacag caggatatgg ggtagtcagt catggagaag gagtagctat tggaatggta
    22621 gccatcactt ctcatgcaga aaaaatcggc ttgtctccaa ctggatcgac agctgcttta
    22681 gaaaggatac ttcaaaaatt ccatctgccg attacgtacg atctaagtca tccagatgaa
    22741 ttattccacg cgataaccca tgataagaaa gcaagaggaa gccaattgaa tatcatcttg
    22801 ctagaaaaga ttgggcaagc aaaaatcgtt cctgttccca cagagacatt caaagattac
    22861 ttaggaggac tgtaagatgc gttatatgac tgcgggagaa tcccatggac cagaattaac
    22921 agccattatt gaaggactac cagcaggatt acctctgtca gaagaagaaa tcaatcacga
    22981 actcgctcgc agacaagctg gttacggcag aggaggaagg atgaagatcg aaaaagatcg
    23041 tgttcggatc acgtctggca tccgtcacgg caaaacaatt ggttcacctg tcactttagt
    23101 ggtagaaaat aaagattgga aaaattggac aactgtcatg tctgtagcag aagtgcctga
    23161 aaaagaccaa tcactgcggc gagttgcacg tccgcgtcca ggacacgcgg atttggtagg
    23221 cggtatgaaa taccatcatc gagatcttcg gaatgtgctt gaacggtcct ctgcaagaga
    23281 gacgaccatg cgtgtagcaa tcggcgcaat tgccaagaaa attctggaag aacttgacat
    23341 catcgtagca ggacacgtga tttgtcttgg tggaatccaa gcagaaatac ctggaaatat
    23401 ctcgattcaa gaaatcaaag aaatttctga agcgtcagaa gtacgagttg ttgatccagc
    23461 agttgagcaa agaataaaag atttgatcga tcagacaaag aaaaatggag atacgatcgg
    23521 aggaattgta gaagtgctcg ttggaggcgt tccagctgga ttaggaagct acgtacaatg
    23581 ggacacgaag ctagatgcca aaatcgcaca agctgtggtt agtatcaatg cctttaaagg
    23641 cgtagaattt ggggtcggat tcacttctgg ttcattacca ggctcagaag tgatggatga
    23701 gatcctatgg gaagaagaaa gaggctattt ccgacgtacc aataatctag gcggcttcga
    23761 aggcggaatg accaatggcg aaccacttgt cattcgcggg gtcatgaaac ccattcctac
    23821 attgtacaag ccacttcaaa gtgttgatat cgatacaaaa gaaccttaca aagcaagtgt
    23881 agaacgttcg gatagtacag cagttcctgc agctagcgtc gttgcggaaa atgttgtagc
    23941 cactgtggta gcgacagagc tattgtcaaa attcccaagt gattcgcttg ttgagttgaa
    24001 agctgcagtg aaggagtacc gtgactactt gaaacattac taaaaagggg gcaaataaga
    24061 tggcacaaca tgtttttatc gtggggcttg gactgattgg tgcttctatg gcactttgta
    24121 ttcgtcagac caatccagaa ctgatagtag ttggttggga tagtcagtca aaaacccgtg
    24181 agcaagcagt agaacagcag atcgttgatt acgttgcaag tgattttgaa acaggtgcag
    24241 aacaagcaga cgttatctta ttagccgttc ccgtccgtac aaccttagct tatcttgatg
    24301 tccttgaaag aatcaacttg tctgatcacg tcatcattac ggatgtcagc agtacgaagc
    24361 agcaagtcgt gacatccgct gagcagaaaa atcttcggtt tgtcggtgga catccaatgg
    24421 ctggttctca taaatcaggt atacaggcag cagatgctaa actatttgaa aatgcctatt
    24481 acatctttac acctttggaa aagacgaaaa aagatgttga aaaactgcaa gaactatttt
    24541 gcggaaccaa agcaaaatat gtaactctta cagcaagaga acatgaccgt ataacaggaa
    24601 tgctaagtca ttttccacat attctggcag ctggcttagt caatcaggca gaacaattca
    24661 atcaagagta tccgcgagcc aaacaactgg cagcaggagg ctttcgagat atcactagga
    24721 tcgcttcctc agatcctgtc atgtggacag atattttgtt gagcaataag cagatattat
    24781 tggaacgatt ggcagattgg caacaagaaa tgacacaaat agcagaatgg atcatgactg
    24841 agaaccaatc ggaaatcttt tcttttttca atcgggcaaa agaaagtcga gaccagttgc
    24901 ctgtccataa gcaaggcgcg attcctgcct tttttgattt atttatcgat gtgccagatg
    24961 aacctggcgt tattgcagaa gtaactggac tgatcggaaa agcgggagtt tctttgatta
    25021 atttgaagat ccaagagacc agggaagata ttttaggaat actgcaaatc agttttaaaa
    25081 accaacagga tttgttacaa gcaaaaagaa tcattatgtc taataccagt tatcattgct
    25141 ggatcaaata ggaggctgga taaatgcaat tattacaaca aatacatgga ttaagaggga
    25201 ctgttaggat accagcagat aaatcaattt cccatcgcag catcatgttt ggagcaattg
    25261 ctgaaggaac gacgactata caaaattttt tgcgcgcaga agattgtctg agtactttac
    25321 atgccttcca acaattaggt gtcgagatcg aagaagagga agaggtgatc aagattcatg
    25381 gtcgcggtag ccactcattt gtccaaccaa ccgaatcaat tgacatggga aactccggta
    25441 cgaccatacg tttattgatg ggtattttgg ctggacagcc ttttacgact actctgttcg
    25501 gggatgcttc gttgtctaaa cgtccaatgg ggcgagtgat ggaaccttta cgcgagatgg
    25561 gcgctgactt gcaaggagaa gaaaatgacc agtatctacc aatcactgtg acaggaaccc
    25621 gctctttatc acctatccga tacaatatgc ctgtagccag tgcgcaagtc aaatctgctt
    25681 tgctgtttgc ggcattacaa gcagaaggca catccgtaat cgttgaaaaa gaacgttccc
    25741 gtaaccatac ggaagaaatg attcgtcaat ttggcggaag gatcacagtg gaagataaaa
    25801 cgatcatagt gaccggaccg caaaaattaa ctggtcaaca gataactgtt ccaggtgata
    25861 tttcatcagc tgctttcttt ctagcagcag gacttcttgt tccggaaagc caactgttgt
    25921 taaaaaatgt cggggtcaat ccaacaagaa ctggtatctt agatgtgttg gaggagatgg
    25981 gcgcagcgat tacccagacg aatcacaatg aacagaacca atcggctgat ttaagtgtca
    26041 agacgagtca tttgaagaaa gcaacgattg gtggagaaat cattccgcgt ctgattgatg
    26101 aattgcccat tctagcttta gtggctactc aagcagaagg aatcacgatc atcaaagacg
    26161 cagaagaatt aaaagtaaaa gaaaccaaca gaattgatgc ggtggcagaa gaattacaga
    26221 aaatgggagc aaagataaaa gcgacagcag acggtctgat catccatggg ccgacacctc
    26281 tgcatggcgc aaaagtgtcc agcagaggcg atcatcgaat cggtatgatg ctgcaagtag
    26341 ctgctttgat agctgatgga ccttgcgaac tagaaggagc tgaagctgtt tcaatctctt
    26401 atccggcatt ttttgacgat ttagcagaac ttgtgtcagg aggagaagct catggctagc
    26461 attttgctga ttggtttcat gggcgctgga aaaacaacaa tcggtaaagg gttagctcaa
    26521 tgtttacaaa aagagtatgt agatttagat acaaagattg aggaacatat ccaattgtcg
    26581 attgccgaat attttcacta ttacggtgaa aaaagctttc gaaaagtgga gtcagatatt
    26641 ttaagaaagc tgtcaaatga agacaaaatt atcgcgactg gtggagggat tgtccaaagt
    26701 gcagaaaatc ggcgtttttt aaaaacacag ccgattgttc tttacttaga ggcagaagcg
    26761 gactgtctag ttgatcgtat ccaacaagat gaaacgtcta ttcgaccttt agctcttgga
    26821 aaaacaagag aagaaataaa agcattattg gcacaacgac tttcttggta tgaagaaagt
    26881 gcgacacatc gaatcaacac gaccaatcaa acaccagaaa agatcatcga taccattata
    26941 gaaaggatca aaagcatatg aacgtcagct atctagggcc agaaagttca ttcacttatc
    27001 aggcggcttg tcagctattt cctacagaac aattgactgc gtatgcttcc atccctgttt
    27061 gtttgcgcgc tttgtttcgc aaacaagtcg atctggctgt cgttcctgta gagaattcat
    27121 tggaaggagc tgttcatcac acaatcgatc ttctttccaa acatccagaa gtcgaagtta
    27181 aaagtgaaat cgttcttcct atcaagcagc agcttttagg caatccagca acaaagatta
    27241 caaaaatcct ttcacatcca caagcactag cacaatcaca acagttttta gaaacgcatt
    27301 atcctaatgt tcctttagta gcaacagaat caacaactgc tgcagcaatg tatgtagcag
    27361 aacatccgaa agaagacgca gcagcgattg cttcattaga aacagcacag catgttggat
    27421 tggagatctt agctgagaat atccaagata atgagttgaa ccagacacgt ttttggatcg
    27481 tcggtgaccg aaagatgacc agccagcagt cagctccagt aaaaatgagt gtcatcttga
    27541 cactacctgc taatcggcca gggatgcttc ataaaatgct ggcagctttt ggctggcggg
    27601 aaatcaactt aagtaagatt gaatcccgac cattgaaaac tagcttggga gaatattttt
    27661 tcgtgatcga tttgttgttg gaccgtccaa tgacattagt agagaatgcg ctccaagaaa
    27721 tcaagatgct cggaggagaa agtcaaatat tgggctgtta tccagtgctg acagtagaag
    27781 agacgcgtag atgaaagtca agaatactga ttgatttatt taacttaaaa taaaaaaatc
    27841 agcgcttggc tattctttat ttttgatatt ctgattgatt tttaggaaga agcggtagac
    27901 aaatcgttac agtcgttcct gtcccaatca ctgattggat cgttaagcca tatgcatcgc
    27961 catacattag gcgtatccgc tcatctacat ggctgatgcc gattcctgaa aaatgatcat
    28021 ttttttgttt ggtattttca gtatcgaagc catcgccgtt atcaatcact tcgaataaaa
    28081 gaagctgatt ttttgttttg ccgtacaccg tgatgaatcc ttgcgtttta ttgtgaaaag
    28141 catgaagata ggcgttttcg ataattggtt gaaggatcat attcggcata gataatgact
    28201 gcagttcatc aggaatcatt attttagccg agattctttc gccatatcgc atactcaaaa
    28261 gatcgatgta actttgtacg cttttgattt cttccttgac tggaatcact tcttcttttt
    28321 tcccaatcgt acttcttagt aaagtaatga aactgtcgat tccttgaact gcttcatctg
    28381 tttttttctg ccaaatcaaa aatttcaagc tagtcagcgt attataaata aaatggggct
    28441 gtatctgtgc ttgcatagtt tggatttcaa gcgaacgttt cttcttttcg tcttggatcg
    28501 tctgttcata atgatgctga gcattactta gcaattgatt gatcgtattc cctagcaatt
    28561 ggacttcatg gcttccttgt acaggaacag tagcttttaa gccatcttcc tctagccgtt
    28621 ttagcgaatc aatcaagcgg tagatcgatt ttgtgtgtcg atccaaatac ataaatacca
    28681 atgagccagc aaaagcaagt gtcacgatat tatacaaaat aatcggaaaa atcacgccca
    28741 tttggttaga taaagaatga agatcgactt gactgagtaa tgtacaatcc tggcggtaca
    28801 gaggaagacg ggtcaactgc tgtccatttg aaatcgttgt ttcacctact gttagttttt
    28861 tgaaaatcat tgatcggctc ccaattgtat tttcttcatt tgatgcgatg atcgtctgtt
    28921 cttcgttcat gaaggagatc ttcgatatct caggatttac tacagattga aaaagattcg
    28981 ctagttgctt ggatgagatc gataaaacag catatccgta aacgtgattc aatgtatttt
    29041 tcagtttttt gacaaagaag acgctgggtg ctttcttatc gcgaagagtc aatccgtggt
    29101 gtgcaaaaag catttgtgta tcagcagcac gttcattcac tctctgagca atcgcagatt
    29161 gaaaaaaaga atcggcagat acggcagtga gcatgtcgtt tccgacaaaa gttcttccat
    29221 tttctccaaa gatcaataca tcgtaatcga tcattggatg gatttttgaa agagagtcat
    29281 tcattttttg gattgttctt agttgctgaa gctgttccat atgttgggct ggatcattgg
    29341 aaaaatagct tttgacagct ggattagaat caaaagcggc taatgtattc tcgattgtat
    29401 cattcaaact ttcaaattca gattgaatct tttttagtac cacatcattc gattgattga
    29461 acagctggat ataggcatcc cttgatcgat gataaataaa caaagaaatg acgatggctt
    29521 gcagaaaaag accgatgaac aaaatgaaca gaagtttggc aaagagttca tgctctttga
    29581 ttttttttct cattttacaa aagttccttt acggtattga gaaggtgtca ttcctgtctc
    29641 ttctttaaaa actctggaga aataacccag ttcggtatag ccgactttct cacagatttc
    29701 cgtcaaagta agccgtgttt ccgtcaaaaa gagcttggct ttactgatac ggactttttt
    29761 tagatatttt gaaaagttga taccaaattt ttcagtaaag atggctgaga gatagctata
    29821 tgaaaaatga tatttttcgg ataaaagttg taaattgatt tctttctcat aattttcctg
    29881 gacgaactcg tagatcaaag tcaagatatc gaaattgtct ttttttgcat ttgcagaaaa
    29941 gtgggtgagt ttctcaagtg tttctttgac aagaatagaa aaatcttcga aatactcagc
    30001 atcggctaat aaagaaggaa gggcgatctt gagcaaagaa agttcttcat tcccaacatg
    30061 ctcgtcagcc aaagcgttga gtaatgcata gaaacgattg attgcctcat gtttcaaata
    30121 agctggatca ataggctgtt ccaatatcgt cgtgaagaaa ttctcaagtt ctttgacagc
    30181 taaagcgtag tctttatgaa cgatttttgt taaataacta cttgcttgct gctcgtggtt
    30241 ggttaataac ggaagaagtt catgctgata agcaaggttc tttcccttat gatagaaacg
    30301 ttgtcctttg gtgcaatttc tgatctcttg gaatatttca ttgatatctt ggattgcaaa
    30361 agaatcagaa acaacaaaaa aatcacctgg aaaaacttct tgacgaaact tttgaacaaa
    30421 cttcctaagt gtatctttgg aatcagtatt gattacatag ccggattctt ccgaaaaggt
    30481 agaaacagga taaatagtaa acgaatcgtc gctatccatc aatgaatggg tgatcgactg
    30541 tttttgttta gagccttgtt ttgaactgaa tggccgtttt tcggtatata acagaaaaac
    30601 aaggtgtgtt caaaaagaag agggtcaagc aatggacgag tttgtccagc aatctgctgt
    30661 gaaagattct cgcagatctg ctcataacga ttggtgattg ggcttttgtt gggctttttt
    30721 ttgatttttt gtgaaacggc agttaaggaa tttagaaaaa aatcaggact caatcgaggc
    30781 tttaaaagat aatcagcgac gccttcttta aaagaatctt taaccatatc aaattcatca
    30841 tagctagaga ggataaggat ctgtgtttca ggttgttgct gttttaatag ccgcgataat
    30901 tcgattccat ttaattcagg catcattaca tctgtgacca cgatatcgat tgcatgtacc
    30961 aaagaaaaat caagcgcttt cagcggactg gaaaaagtcc ctattaattg aaacccgtgc
    31021 tcagaccaat tgatcaactg tttcattcca tctaaaatcg tctgttcatc atcgataaga
    31081 attacgcgta ttggcatttt tttacccgcc ttaagaatag tcttgtaatt taaaaatact
    31141 tatttctagg agaaaatgca aggatatttt tattttaaag aaacctcacc atttcgatct
    31201 ttggtctaga tgctaagatt attccttttg tcatagttga tttgtatttt tttattattt
    31261 taggagaaat ttttgaagta tctgaataat aaagaaaccg ttttcaaatt ttggtatgat
    31321 gaatgtagca aacgtaaaca actaatggat ggaaaaggag cggataaaaa tgaacatcag
    31381 aaagttaatt gctggagtcg tttgtttagc ggcagcatca ggtttcttaa caggatgcgg
    31441 aagtgctagt agtacagcag acaaagaaga aaaagtcact gtctgggcgt gggatgagac
    31501 attcaatatc aaagcagtga atgaagcaaa aaaagtttat gagaacgaag aaacagagat
    31561 agaagttgtt acgatgtctc aggatgatat cgttcagaaa ctgaacaccg ctttagcgag
    31621 cgggaataca gaaggattgc ccaatatcgt cttgattgaa gattatagga tacaaggcta
    31681 tttgacttct tatccagatg cattcgctaa tttgtctgct attgtaaagg aagatcattt
    31741 tgcaccgtat aaatttgcgg taaacaaagt aggagataaa atatacggtg ttcctttcga
    31801 ttcgggcgta acagcaaact tctatcgtac ggatctgatg gcagaagcag gttatacaga
    31861 agaggatatg gagaatctga agtgggacga gtatattcaa gtagcgcgag atgtcaaaga
    31921 aaagacggga aagaaaatcg ctgaagtcaa tccttctgac cttggtcgag taaggatgat
    31981 tatgcaacag gcaggagaat ggtatacatc tgaagatggg gagacagtca cgatccaaga
    32041 caatgcatct ttaaagtatg gtcttgaatt gtttgccact cttttgaaag aagatctagt
    32101 cgaacaaacc tctgactgga atgctggagt aactgcgata caatcaggag cagtagcttc
    32161 tagcccaact ggcgcttggt attcttcaac gatccaagga gcagaaaacc aatctggaaa
    32221 atggaagatt gcaccaatac ctgcacttcc agaaaatctg caaaaagcgc aagcttctaa
    32281 ccttggcggc gctggctggt atgtgatcaa aggagtagct ggagaagatt cagcgaaaga
    32341 tttcctagaa gcaacgtttg cttcgaatga agaactgatg ggcactcttg cgaaagaaat
    32401 cggactagta tctacgatgc ttagcgcgaa tgaacaagaa gcttatcaag aagcttctga
    32461 attttacagt ggtcaaaaga tctttgacga tttttcaaca tggacatctg aaataccaga
    32521 agtgaattac ggacatgaga cctatgcaat tgaagcagtc gtagctgaag ctcttcatcg
    32581 aatcatcaat ggagaagaga cagacaaggt actagcagat acacaaaaac aagtagaagc
    32641 acaattggct aattgatcgg tggtaaaaaa gtgaatttct tcgctttttc atcagacaaa
    32701 cgaaaagaca aaaaagatca cgtctgcctt acagatattg tctttcttgt cttttcatgt
    32761 agataatcaa tgatagaatt ggagggaaaa gaatgaagca gaaagattta ttcaaaaacg
    32821 ggcatgcttt tttaatcttg ccagtcattt tgatatcaat catggttttt attccgatgg
    32881 ttttggcttt gatcacgtct tttcaaagtg gtccccctgt caatatgaca tttaacgggt
    32941 taggtaatta tcagcggatg ttgacagatg caacttttaa aaaagctttt tttaatacat
    33001 tcctgtattt acttgtacaa gtaccgatca tgttgtttct agcacttttt atttccaacc
    33061 ttttaaatga taaaaagttg aaatataaag ggttgtttcg aaccgctatc tttcttccat
    33121 gtatcacttc gatggtcagt tattctctga tcatgaaaag tctattttct caatctggcc
    33181 ttgtaaacaa cttgttgttg ggcattggta tgattgacac accgattggc tggttgactc
    33241 atccaatttg ggcgagagtt ctgatcattc tttcgatcac ttggcgttgg actggataca
    33301 atatgatttt tttcctttca ggcatgcaaa atattgattc ggagatttat gaagcagcat
    33361 ctattgacgg tgcttctaaa tggcagcagt ttatcaaagt gacgatccca aatttaaaac
    33421 caatcatttt gtttacttcc attacttcga cgatcgggac attgcagctt tttgatgaag
    33481 tacaaaatat tactggcggg ggaccagcaa atgcaacgac caccctatct caatacatct
    33541 ataatttgag ttataaattc acgcctaatt ttggatatgc ggcagcagtt tcctttgtta
    33601 ttgtttcctt tattgtgata ttgtcgataa tccaaacgaa agtaggagga gaaagtcgat
    33661 gaaaaatatg gtagaaaaag aaacaatcga acgccccaac gtcaaaaaac aagcattaga
    33721 acttcgttcg acaattgggt cagtattaaa gtatacagca ttaagcatcc tatcatttat
    33781 ttccattttc ccttttgtct ggatggtttt gggaatgacg aatacacccg tggatatcac
    33841 atcgggaaaa ataaagattg gcagtaactt gatcatcaat tttcaaaatt tgttttccaa
    33901 tgagctgaat tttactcgtt ccctttggaa ttcagcgatg atcgctttgg tgaccactgt
    33961 gtttgcattg ctgatttcgt caatggcagg atatggattt gagatttatc aaagtaaacg
    34021 aaaagaccta attttcaata ttctactgct atcgatgatg gttccttttg cggcattgat
    34081 gatcccttta tatcgaatgt tttcacaatt gaacggaacg gttttgggaa tcaacagttt
    34141 cttggttgtc atcctgccat ctgttagcac tgcttttttg atcttcttct ttcgacaaaa
    34201 tgttaaatct tttccaaaag atctagtaga agccgctcga ttagacggtc taaaagaact
    34261 aagtattttt tttagagtgt atatgccgac ggctaaaaat acctatgccg cggctgcaat
    34321 catcacattc atgagtagct ggaacaatta tttatggccc ttagtagctt tgcaatctcc
    34381 tgataaacgg acggttccgc ttgttttatc tgctatgggt gcttcctata caccagacta
    34441 tggaatgatc atggctggat tagtcatcgc tactttacca actgccatcg tattttttgt
    34501 tttgcaaaag caattcgttc aaggaatgat cggctctgta aaataaaaaa acacaataag
    34561 cgcgttcctt caaagtcatt tttccaagta aaaagatact tttgggacgt gtgttatttt
    34621 atgttgagaa aaattaaatg ataacgtttt aagtttgtgc tcgaaaactc tttcatttta
    34681 aggtaaactt aaagagtaaa ggaggaggat acatgctaaa aaattttaaa gaagtgattg
    34741 ctgctatatt gccgatgact gtcctgattg tcattttaac gtttgttttt gcaccgttag
    34801 aaggagaaga cctcgcttca tttctggttg gtgcggcaat catgatgatc ggaatgacgc
    34861 tctttttgtt tggagcagat tattctatga tggaagtcgg agatctagta gggaaatata
    34921 tgatcaaaaa gaaaagtttg accgttttgg tcagtttggg atttgctatc gggatcgtga
    34981 tcacgattgc tgaaccttcc gtgcaagttt tgggacaaca agtatatgat atatctgacg
    35041 gagagattgg cagagtgttg ctgattggga tcgtcagcgt cggcactgga gtatttctag
    35101 cctttgcgct gcttcgggtc gtattcaagc tatcctatta tcaattgatg gctataggct
    35161 acataggcgt tttgatcgcc tcatttttca ccagttccga atttatgccg attgcttttg
    35221 attcgggggg agtgactact ggtccagtaa ctgttccatt tatcttggcc cttgccggag
    35281 ggatgactag tatgatcaaa caaaagaaaa atgaaaatga cagttttgga atggtcggta
    35341 ttgcttcgtt agggccgatt cttgccgtga tgattttggg ggtgatcttc caatgagttt
    35401 ctggcagcaa gtgatagatg gaatcgaaat cgttaccatg gaagtcattt tggcagtggc
    35461 acctatcgta atcctatttg ttttaatgaa tatcattagt tttcgtatgc gcaaaaagcg
    35521 tttctttgac attatgaaag gtttcttgat aacgactatt gggttgatcc ttttcctgca
    35581 cggagtcaat atggcttatg taccggtagg acagcattta ggcagtgcta ttgcgggatt
    35641 gccttacaat tatatactgg ttccccttgg ctttttaatg gggttcttag tagggtttgc
    35701 tgagccggcg attcatgtaa tgatcaaaca ggttgaagaa ttgagcgagg ggagaatccg
    35761 atcgaaaatc atgctgatgg taatttcaat tgggatcggc gcagcagtag gattgtctat
    35821 gtggcgtttg ctcgtcggat tctctcttta ttatttcttg atcccaggat acgggctagc
    35881 atttatttta ggacgaaaag tggacaagat ctttttagca atggcttttg ataacggtgg
    35941 agtagcaacg ggcccgatgt gttcgacatt tattttatca atgagcgtgg caatcgctgc
    36001 acaaattgaa ggaagagatc cgatcattga cgggtttggt gtggttgcaa tgattgcatt
    36061 gacaccaata ttatccactt tagtactagg atatatttat aaacgaaaag atgaaaaaga
    36121 cagaatcgaa aaagaaagat tgcaaaaatt gggggaaagc aaatgaaaga tcttgtagca
    36181 ttgaatcttc acatgattgt gacgatcgtt gacggaggaa tgggcgaaga tgttatcgac
    36241 ttttcaaaag aagcaggtgc agcaggcgga acgatcttac atggaagagg ttctggtgta
    36301 catgattcag ggaaattttt aggtttggac atttcgccag aaaaagatat tgtgttgaca
    36361 ttagtacccg atagtttgac gaataaagta atggatgcga ttggtcaagg catcaacatc
    36421 gatattccag gtaatggtat ttgttttagt attgatgtag acaaagtcat tggtatcact
    36481 aagattcatc aatatcgaga aattatcgga atgcaagaac ttttagatga aaataacgat
    36541 agagaaaagt ctgaatcata gacaagcgtt tgaagaggaa ataaacacaa acaagaaggc
    36601 ggatgagcgt tatttccgct tttttgtttg tatttttctc gtgaatactt atgaaatagt
    36661 aaatttttat gaaattctac tctaagcatc agactttctt ttcaaaatat gctattttaa
    36721 aaatgatgaa aaaaggggga gaaaaatgaa ttttttagtt gttttaaaag atactctgat
    36781 tgagcgattt acatttctat atgttcaatt gcaggaaaat aaaacattgc tgcatttttc
    36841 accagagttc catctagagg ggctaacatt aggagaaatc tatcaagcag aagggctgtc
    36901 ggctgttttg cactttttta aggtagaatt ggaattacca gtaaaagatt atatcgagct
    36961 ttctcttgaa tcttgggatc gagcagtggt tgaactgttt ccagaaggtt taatgatcga
    37021 tacaaacgat gggaagatcc atctgactgc agcagaactg caaaaacaaa tgcgttatca
    37081 aatagatgac gaaaattctt tttctatttt tagacgtcag caaaagattc taaaaagctt
    37141 tttaaaagtg atcagtaaaa aacggaatct gatcaaaacg acacagctgt tgaaaaaata
    37201 tccaggtctg cttcacacgt ctattcaatt tcctcaattg attacgatga tccatcgttt
    37261 tatacgtatg caacagctac catctaagaa gctgtttctt ccattgacgg acacatttcg
    37321 agtagtcaac agagaagata aaaagaaagt gattgtgatt gactttacca gaaatcggaa
    37381 tgtccttcac caagttgcaa tggaaaaggc caattaaggc tttttctttt tggatttttt
    37441 tgtcataata aatattagat gatggaggag ataatatgat gcaaacatgg ttagaaaggc
    37501 taatacgatt tcagcagaac tatcacaaac ttatgcaggg aagatatgcg aaatttgatc
    37561 agttgaatcg cggtctattg atcgctgcgc ttgtctttag tttgctaagt cgttggttgc
    37621 cctatagaat cggacaattg ttgttcatcg tctttttcgg atggatgata tttcgtttcc
    37681 tatcaaaaaa aatctacccc agactaaatg agaatcaacg ttatttgaaa tatcttgata
    37741 gagtcaaaga aaaatatcat cagataaaaa acaaaaagca agtcaaaatg gatcgaaaaa
    37801 gttatacttt ttttgagtgc ccgaattgtc atcaaaagca gcgtgcacct aaaggaaaag
    37861 gacgaatacg tgtgacatgc aaaacatgtg gtataaaatt cgaaacgaat gtttaaggga
    37921 gaaaagaatg aaattagtat tattacgtca tggcgaaagc gaagcaaatt ttgaaaatta
    37981 ctggacagga tggctagatg tcgccttaac agaaaaagga aaagaacaag cagcagttgc
    38041 cggtcaaaaa atgcttgaag ccggacttca attcgatgcc gtttatacct ctgttttgaa
    38101 acgtgcgatt cttaccggac aagtcgcact agaagaaatg ggtcagttat ggcttcctat
    38161 aataaaaaca tggcgtctaa atgaacggca ttatggggat cttgtgggta aaaacaaaga
    38221 taagatgaaa gaaatatacg gaaaagatca agtaaaaaca tggcgcagag gatatacgga
    38281 agttccgccg ttaaccgcag aaaatagatt tgaccgcaga tatgatcact tggatccgca
    38341 tttgatccca tacggagaaa gtctggaaat gacagtgaat cggatcattc ccttatggca
    38401 agatcatcta gcaccaaaac taaaagatcg gcaagattta ctagttgtgg gtcatggtaa
    38461 tagcatccga gcactgacaa aatatttaga agatgttcct gaagatcaaa tggatacgat
    38521 cgatatccca aatgcacaac caatccagta tacattagca gatgatttga caattctgga
    38581 caaaaaaata ctttaaagaa cacctttatc taaaagtgag agatagaaaa aagaagcaaa
    38641 ggaatggaac aaaaggaaca tgaaaaatta tatatgggac tttgatggta cattgtttga
    38701 tacgtatccc gcaatggtag atggtgcatg gcaagcacta aaagattttg gtatcagtat
    38761 ggacaaaaaa gaaatctact tcaaaatgaa aaagtattct actagttatt tgatcaatga
    38821 atcaaacttg aatgccagag agtttaatga attatttcac cgatatgaaa aagaaagtac
    38881 ggaagtttcc cgtccatttc cagaaacgaa acaagtactg gaaatgctaa aagacaacgg
    38941 cggtcgtcat ttcatcctga cccaccgttt gacagaatca acatggggcc tgttaaaaga
    39001 acatcgattg gcacatctga ttgaggaagt agtagggatc gatcaggact ttcctcgtaa
    39061 acctgatcca gcatctttaa attatttgat cgatactttt catttagaaa gaacagacac
    39121 gatgatgatc ggcgatcgtc gtttagatat cgaagcaggg aaaaatgcag gagtcgctac
    39181 ttgtctttac gacatcgatc attttctggg tgagatcccg gcagattatg tggtaggaaa
    39241 tctgaatgaa atccttacct tgcagagcat cattaaaaag tagtatcccc tttcaaagga
    39301 gatatgttat aattttcata aaggagtgat aaaattatat ggaaatcaga agacaaaaag
    39361 aagttgtaga agcatttcat tatgatatga gattgccgaa ccaagaagta gaaacagatt
    39421 tgaaagtagg cttctcgcct ttaaaagaaa cgatcgaaaa ctatccgaaa gaacatagca
    39481 tcgtaggagc acgcttagag ttccgtttag tgtttgatac atatgtttta tctggaagtg
    39541 tgagtcagat caatcatatc ctcaatcgga aaattgaagg tcaaaatgat gtcacacaag
    39601 aagaagtgga cgagctagta gcaccgttat tcgatatcgt acgccgaatg tcttatgagg
    39661 tgacagagat cgccttagat cagcctgggg taaaattgaa ttttcaatca gaaaaacaag
    39721 aatagacagt aaaaacatac ctgcgataga ttaaagctat cacaggtatg tttttttatt
    39781 actaattgta agcaaaaaga atgtcatttc gataaaaatc gtctaaaata taaaagtcac
    39841 tgaaaaaaat tttttcagga ggatggttga agaatcattc tcgggaacct ttacttcctt
    39901 cgatggactt gtcattaata atatgaggag gagaaaaatg acaacactca tcacagtttt
    39961 agtggttcta gtttttgcgg cattattata tgtgttctat cgtatgcaaa agcgccatac
    40021 aaaattttca acacgcgtct ttacagcatt aggagttggt atcgtctttg gcggtctgct
    40081 tcaattgatc tttggtgtag acgacaaagt cgttactcaa tcaatggaat ggatcgggat
    40141 tgtaggtcaa ggatatgtat cattcttgca aatgctagtt atgcctttag tgtttatttc
    40201 gatcattggt gcattcacaa aaatgaaagt ttctgaaaag ctagggaaaa ttagtgcgac
    40261 tgtattgact tctttacttg gaacaacagc tattgcagca ttgatcggaa ttggttcaac
    40321 aatgctgttc ggactccaag gagctaaatt cacacaagga gctgcagaaa cagcacgaat
    40381 ctctgaactg gcaacacgtc aggaaacagt tgaaaactta tcgattccac agcagatttt
    40441 atcctttatc cctaaaaacg tttttgctga tttagcaggt agtcgtgcaa caagtacgat
    40501 tggagtcgtt attttcgcgg catttgtcgg aatcgcttat ctaggcgtga aaagaaaagc
    40561 gccaaaagaa gcagcattct tttcagattt agtcgacagt ctgtataaaa tcattatgcg
    40621 gatcgtgacg cttgttttgc gtttgacacc ttatggagta tttgctttga tgacaaacgt
    40681 tttggcaaca agtgattttg cagctatcgt caatttaggt aaatttgtcg ttgcttctta
    40741 cgtagcattg cttgctgttt tgattgtcca ctcactgatt ttgattggtg caaaagtcaa
    40801 tccaatcaac tatttcaaaa aagcctttcc ggtattgagc tttgcgttta cttcacgttc
    40861 aagtgctgga gctttgccat tgaatatcga gactcagaca aaagctttag gagtagatga
    40921 tgcaacagct aatttctcag caagttttgg tttgtctatt ggacaaaacg gctgtgctgg
    40981 cgtttatcca gctatgttgg caacgatcgt cgcaccagca gctggagtga atgtctttag
    41041 tttggaattt attttgatgc ttgtggcaat tgtaacaatc agttcttttg gtgtagctgg
    41101 agtcggtggg ggcgcaacat ttgcttcact gatcgtttta ggggcaatga acttgccagt
    41161 agcaatcgtt gggttagtta tctctgttga accattaatc gatatggcac gtacagcagt
    41221 aaacgtcagc ggtagcatgg tagctggtat cgtgacaagt gcacgcatca aagatttaga
    41281 tcgcgatgtc atcaatgatg attctaaagt gatcgatgtg aatgcatagt caaaaagagg
    41341 ttgtgataga agtggtcagc tttaagaaat aagaagaagt ttcctaaaaa tagtttctca
    41401 aatttttgtg aaatttcggc ttatttccga gaagctactt ctgaaacacc gtgaataaga
    41461 ggttgtgaaa aagctgccct gcatcaagta ataagaacag ccaaacaaaa atagttcctc
    41521 atattttacg tttggttgag cttattaccg cagatgcaag cttttgaaca ccgtttaaga
    41581 aagaggtcgt gagcctgccg tttcactctg agtcacaaag agcaatttca aaaaatagct
    41641 tctcatgttt gttgaatatt gtgtcttgtg accgaggagt tgtcaggaga acaccgttta
    41701 ccagaggttg tgacttgttt ttagtcacga cctctttttt tatttattcc atataaatac
    41761 acattattta ttccgaaaag tgaaagcgca aataacaaaa acaaccaact tatttattat
    41821 taaagaaaag cgtatttaag taggacgatt ctgttgagag ctttcgtaga ttttcccatt
    41881 ttcctatggt aaactgacaa agttgagaat gttagaacag atcgtttagg aggaaacaga
    41941 tgtttacgaa tgaaataaaa atcatgcttt atgtggacga tgtagaaaaa aatgcaacgt
    42001 tttggagagc agttggcttt gcggaaaaag atcgtcaaga aatggatggg acgcttataa
    42061 ttgaagtagg agttgaggac agtcaaacct catttctgtt atatgatcga gcatttgttg
    42121 agtcccattc acctggcaca gctactagtg ccccatcttt gatgttttac agtaaagata
    42181 tctttggact atataaaaaa atgcagacgc aatcagtcac attaggtgat atggtacagc
    42241 ttggagaaga atatgtcttt aactttgctg atcccgatgg caactacttt gcggttacag
    42301 gtaaataata gaaataaaga ctttgttttt ctgtgcgaaa caggaaagcg aagtcttttt
    42361 aattcaaata ataatattat gtaaacaaaa aactttccat gcgtaattat acacaagcaa
    42421 ataaatcgtc aaatgcgaac gccttcttta tactgtttag gaacgaaaag aaggaaggaa
    42481 gaaatacatg gattatcaag tactgcttta ttacaattat acaaaaatcg aagaaccaga
    42541 ggaatttgcc aaaaatcatt tagccttttg caaatctttg gatcttaaag gtcgtattct
    42601 agtagctgaa gaaggaataa atggtactgt gtctggaacc gttgaaaaca cgactgccta
    42661 tatgaaagca atgaaagctg atcctcgatt tgctgatacg atgttcaaga tcgatccaag
    42721 cgaaggacat gcctttaaga agatgtttgt aagataccgt ccagagcttg taagtttaaa
    42781 gctagaagag gacattgatc caaaccaagt gacaggtgcc tatctttcac cgcaagaatt
    42841 taaagaagct attttagatg aacagacagt ggtgattgat gcacggaatg attatgaata
    42901 tgacttggga cattttcgag gggctgtacg cccagatata cgcagttttc gagagcttcc
    42961 agactggatc cgcgagcaca aagaagaatt tatggaaaaa cgggtagtga cctactgtac
    43021 tggtggcatt cgttgcgaga agttttctgg ttggcttgtc cgtgaaggat tcaaagatgt
    43081 cggacagctg catggcggta ttgctactta tggtaaggat cctgaagtcc aaggagaatt
    43141 atgggacggc aagatgtatg tgtttgatga acggatcgct gtcgatatca accaagtaga
    43201 taaacaaatc gtcggtcgcg actggtttga cggaacacca tgtgaacgat atatcaattg
    43261 tagcaatcct gagtgcaatc gtcagattct tgcttccatt gaaaatgaag aaaaacattt
    43321 aggagcatgt agcatagagt gtgcgaaaca tccgcgcaat cgctatgttc aagaccatgg
    43381 aatctctcca gaagaagcag aactgcggtt tacagcttta attaaataga aaacaatagt
    43441 tttgattgtc gaccatttcc aatatgcgct atactagcgt tgaggatggt gatccacatg
    43501 aaatcattga tttatgctat tggggatgtc catggcaaac atgagctttt tgaaaaactt
    43561 attcactatt atgatccaaa gatccatcag cttgttttat taggggatct caatgatcga
    43621 ggtcctcgta caaaagaatg ttttttatta ggaaagcaat tagtcgaaga aacaggagcc
    43681 atttacctcc ggggaaacca tgaagaatat tttttgcaat ttctgcaatc accggaggac
    43741 tggtatgcgc cttatatgag aaatggtgga aaagaaacgt ttgaaagcct gattcaccca
    43801 ggggcatcgg aggaatactc cccaactgaa atctcgatga tgatccaatc gagatattca
    43861 gaactgatta aatttttagt ccagcgcccc ttgtattatg aatgggaaaa ttatcttttt
    43921 gtccatgccg gtgtggattt gacaaagaaa gactggcgta agacaagtct aagagacttt
    43981 atttggataa gggaaccatt tcatgaaggg aaaaacaata caggtaagac aattgtattt
    44041 ggacatacga ttacaccaat gctccatgga gatatgcaga caacagacct ctggattcag
    44101 gatcataaaa tcggaatgga cggtggggct gtattcggag ggtcattgca tggggttgtt
    44161 tttgacaagg aaggtattct tcaagatatt gaatatcaga acaacgaagg accttggcat
    44221 ggaatctgac taatggaaag aatgaaggag ctgtgacttt gttgcggctc tttttatttt
    44281 tatagagaat attgtttctt tcagtagttt aacccaggat aaaaagtatg atagaataaa
    44341 gaagcaattt ttagcagaaa agaggcattt taatgacgga aaatttgaac cagacgatca
    44401 ttcagcttgt acaaaaagaa ctttcagact atcgtcctaa gcagttgact actgtactta
    44461 atttgttaaa tgaaggaaac actgttcctt ttatcgcgcg ttaccgaaaa gaaatgactg
    44521 gaagtcttga tgaagtccag attcgtgaaa tcgaagagcg gtatgcctat cttgaaaact
    44581 tagaaaaacg taaaactgaa gtgattcggc taatcgatga acaagggaaa ctgactcccg
    44641 agttagaagc agaaatcacc caagccgtga aaatgcaaca agtggaagat ttgtatcgtc
    44701 catacaaaca aaaacgacgg acaaaagcaa cgattgctaa agaaaaagga cttgaaccac
    44761 tcgcgaagtg gctgatgcag cttacagatg gagaggtgca atctgaagca gaaaaatata
    44821 ttgacaaaga aaaagaagtc tcttctgccg aagaagcgtt gcacggtgct catgagatta
    44881 ttgctgaaca agtcagcgat aatgcaaaat ttcggacttg gattcggtct tatacgtata
    44941 acaaaggtat gtatgtcagc aatgtcaagg atgagcaagc agatgaaaaa ggcgtatatg
    45001 aaatgtatta tgactttgca gaacccgtcc ataaaatggt ttctcatcga atattagcta
    45061 ctaatcgtgg agaaaaagaa gatattctga aagtattctt tcaagtagat gaagcagcaa
    45121 ttttagctta cttggatcgc caaatagtca aaaatcctgc ctctccttct tcttcattcg
    45181 tcagagaagc ctatcaggat agttataaac gctttattca gccagcaatc gagcgagaac
    45241 tgcgcaatga attgactgaa aaggcagatg agcaagcaat cgctattttc ggcgaaaacc
    45301 tccgtaatct tttgttgcaa ccgccactaa aaggtaaagt tgtcctggga tttgatccgg
    45361 cttatcgtac tggatgtaaa ctagcagtcg tagatgcgac agggaaagtt ttagcaatcg
    45421 aagttattta tcctcataaa cctgcagcgc aagcaaaaag agaagctgct ggaccagctt
    45481 ttatccaatt aattaataaa tatcaagtag atatggtagc tatcggaaat ggtacagcca
    45541 gtcgggaatc tgaacttttt gtggctgagc agttgaaatc cgccgaccat aaaacctatt
    45601 acgctatcgt caacgaagca ggcgcttctg tttactccgc tagcgaaatt gcacgaaaag
    45661 aatttccgca tctacaagtt gaagaaagaa gtgctgtttc tattgcccgt cgcctgcaag
    45721 atcctttagc tgaattagtc aaaatcgatc ctaaagctgt cggagtaggc cagtaccaac
    45781 atgacgtttc tcaaaaacgt ttggctgaac aattggattt tgttgtggaa acagcggtta
    45841 accaagtagg tgtggatgtg aatacagcaa gcccgcagct cttgcagcat atatcaggat
    45901 tgaataaaac aactgcccaa aacattgtca tttatcgtga agaaaacgga gaattcaccg
    45961 cacgaactca attgaaaaaa gtgccacgct taggaccaaa agcatatgaa caagcaatcg
    46021 gattcttgcg agtccctggt gggaaaaaca ttttggacaa cacaggtatc catcccgaaa
    46081 gttattctat tgcaaaagaa atattaactt cagtccaact ttcagaaaaa gagcttggta
    46141 cagaagaagc agtagaaaaa ttgacacgat tatccgtaga gaaactggct gaaagcctat
    46201 cagtcggaga agaaacgtta gccgatattt tagctgggct gacacaacct ggacgagata
    46261 tgcgtgatga gatgccagcg cccttattac gtacagatgt attgagtatg gaagacttga
    46321 aaccagggat ggaattgact ggaacggtcc gtaatgtcat tgacttcggc gcatttgttg
    46381 atatcggtgt gaagcaagac ggacttgtcc atatatcgaa actcagcaaa aaattcgtca
    46441 agcatcctac agatgtcgtg tcagtaggag atatcgtaac agtttggata gaacaagtcg
    46501 atacgaaaaa aggcagaatc agtttgacga tgctttcccc ttatgaagag taacaatgag
    46561 gagtaacaaa aattgacaca agaagaactg cagcagttag tagaagagat atcattaaaa
    46621 agcttccagc ttcctttcaa gcaccaagca atgttcaatc cacgcttacg tacaactggc
    46681 gggcgctatc atttaaacga tcatcattta gattttaatg cgaagctatt tgaagagtca
    46741 gacgaagaga cgattgcagg aatcatcaaa catgaacttt gccattatca tcttcatcta
    46801 gctggaagag ggtatcagca taaagatatg gatttcaagt atcttttgaa aaaaacagga
    46861 gggttgcgct atgcaccagc cttgacgaag aaacagataa agatggagta ttatcgatgc
    46921 caagattgtt ctgccacgat ctgccgcaag agaagaatcg atgtacgcaa atatcgttgt
    46981 ggaagatgtc atggagaaat caaatggatt gagacaaaaa gagaagactt taatgaagca
    47041 caaaaaatca gatgaaagga tagaaggcct ttggaaaaaa gtgagcagag gaatctaaaa
    47101 gactggaatc agctattaaa ttttttagcc gcacctgaag agggaaattt tgaggaactg
    47161 acggcaccta cacttatttt agctggaaac tgtcttccta tcttagctga taaagcagca
    47221 caaatgtatt taaatggcca agtagatcaa ttgtttttgg tcggaggggt ggggcatgcg
    47281 actagaatcc tttatgagaa ttttgaaaag caaggatttc attttgaaga tggcatgagt
    47341 gaaagtgaaa tctgtcgtca gtatctaaaa gaagtctatg atttgcccga taaggctttt
    47401 ctgatagaat cgaagtctac aaattctgga gagaacgcca ctttttcact ggagattctt
    47461 cattccttag gagctgtacc agaaaaaatc ttattgatga atgatccgac actgcaacgc
    47521 aggactcgag caacttttga gaaagtatgg caaaatgaac aaactatttt cgcgaatgct
    47581 gtgccatttg tgccggaaat ccttcacttt tctgaagaga tcatctttac agcaaaagaa
    47641 ctgaatcatc aatggcctaa ggaatatttc catgcgctag tattaggaga aatggaacgt
    47701 ctccatgacg atgagaacgg ctatggtccg aaaggaaaag attttattcc tcacattgat
    47761 atatcagagg aagtttggtc ttcttacacc agaattaaag agtcaataaa aacggatttt
    47821 tctcgtactt gaccatttta gcaagcgaat cctcctttcc aaataaattt ggttgaaatt
    47881 ttcaatcgtt tataagataa tgaggagcgt gttgaatgta atagctaaaa gaatggacgc
    47941 tagataagag aagaggattc aaatggaaaa tcaaaataaa ttgtatcatt ttgttggtat
    48001 caaaggttca ggaatgagct ccttggctct tgttttacat gaacaaggtc taaatgtcca
    48061 aggatcagac attgaaaaat atttctttac acaaagagat ttagaaaaag caaatatcac
    48121 gattctgcca tttaacgcag ataatgtaaa accagggatg acgatcattg caggaaatgc
    48181 atttcctgat tcacatgaag aaatccagcg agcaaaagaa ttaggtttgg aagtgattcg
    48241 ctatcacgac tttattggtc attttatcca aaattatacg agtatcgctg taacaggctc
    48301 tcacggaaaa acaagtacga ctggactgct ctctcatgta ttgagtggtg tccgtccaac
    48361 aagttatcta attggagatg gaacaggaca tggtgatccg caagcggaat tcttttcatt
    48421 tgaggcctgt gaatatcgcc gtcatttcct tgcctattca ccagactatg caatcatgac
    48481 caatatcgat tttgatcatc cggattatta tacaagtatc gacgatgtat ttacagcttt
    48541 ccaaacaatg gctggacaag tgaaaaaagc tatttttgcg tatggtgacg atgcttattt
    48601 acgcaaatta aaagcaaatg tgccgattta ttattatggt gtcacagaaa acgatgatat
    48661 ccaagcacga aacatcgaac gcacaacttc tggttctgct tttgatgtct atcatgggga
    48721 tgaatttgtt gggcacttca ctgtaccagc attcggtaaa cacaatatct taaatgcttt
    48781 aggtgttatt gcagtagctt atttcgaaaa actggatctg aaagaagttg cagaagaaat
    48841 gctgactttc ccaggagtaa aacgtcgatt cagtgaaaag atcgtagcag acatgaccgt
    48901 agtcgatgat tatgcgcatc accctgcaga gatcaaagca acgattgatg gcgcacgcca
    48961 aaaatatcca gataaagaaa taattgcagt tttccaaccc catacgttta cgcgtacgat
    49021 tgcattgatg gatgaatttg cagaagcact tgatttagct gataaagttt acttatgcga
    49081 tatttttggt tcggctcggg aagaacaagg aaacgttaag attgaagacc ttggagcgaa
    49141 aatcaaaaaa ggtggagaag tcatcaaaga aaataatgta tctccattgt tagattatca
    49201 tgatgcagta gtaatcttca tgggtgctgg agatgttcaa aaatttgaac aagcgtatga
    49261 aaaactttta agcagcacga cgaaaaatgt actgtaatac aattactgca gtgtccttat
    49321 aaaaatagaa agagggggag tggcaaaaat cttgccaagc cccctttttt gcaacttatg
    49381 ataaacggtg ttcaaaagct tgcatctgcg gtaataagcc caatcaaatc aaaaacatga
    49441 gaagctgttt tttcttggct gttcttatta tttgatgcag gacagctttt tcacgacctc
    49501 tgtaaactat aggaatctgt taaatcaagg gagcagaact tgccttttac gctacttttg
    49561 gtacaataat gtatgattaa aaataaactg gagggtttct atcttgaaca taggtaagcc
    49621 gagaaaacta ggaaaaacaa taaatgaaat cgaggaaggc gactcgttat ccttaacaga
    49681 atctattgaa gataaccagc ttttgctgta tttgggattg acgaatgatg caaatccttt
    49741 gtatatccaa catgactttg cacaaaaaac agaatatcaa cagccaatcg ttccatcagt
    49801 gatgctgatg gggatcatca caagtgcaat ttcaaagcat cttcctggac caggatcaca
    49861 tgttgtcaat ttttctgtca attttattga accggttttc cattatgaaa cactgacttt
    49921 tcagtttgag gtcataaaag tagataagat gaaggatgtg gtgacgattt ctgtagaagc
    49981 ggagaatacg aacgaagatc gtgtgttgga tgctgtcgtt atggtccaac cgccacaagt
    50041 tcctgaattg gaaatagcaa tcgaaagtga aggtgaattg aatgaataat ccaagtacat
    50101 caatgtcagg tatcaatcgt ttttatgcaa aagtttatgg atttttaggt atgggacttg
    50161 cccttagtgc agtcacttct tacttggctc tttgggtatt tcctttgcaa ttagcaactt
    50221 ttatcaataa ttttccacta ggctttgtgg gtctgtggat cgttgaactg attttagtaa
    50281 tggttctagg cgtaaaagca caaaagaatc cgagcttagc aatcggtgga tttattgcct
    50341 actctctttt gaatggcata acattagcgg ttactcttgc atactacgat attggaacag
    50401 taacgcaagc tttcttgaca gctactttga tgttcatggg gatgtctgtt gtcggagtaa
    50461 caacaaaaag agatcttagc ggggttggaa gagcaggaca ggcagcttta atcggagtga
    50521 tcattgcact agtcttgaac atcttcattt tgagaagtag cgtagttgag ctgttcatct
    50581 ccctactgtt agtcgtcatc tttgcaggga ttacagctta tgataaccaa agcatccgta
    50641 atatctatgt ccagacaaac ggaacagcac atagtggaat tgctgtattc atggcattga
    50701 agctgtattt ggactttatc aacttgttct tggcgtttct gagaatcttt ggacggaaca
    50761 actaaaaaag aaaaaaattc atcagttggg gctataccga attatttggt atggtcccgc
    50821 tttttctttt cgcattccgc aggattcttt gttagaatga ataagaactt tacagtaagg
    50881 agttaagaag atgacaaaaa ataaattatt actcgttgat gggaacagtg tggcttttcg
    50941 cgcattcttt gcgcttcaca attctcttga acgtttcaaa aatagaaacg gtcttcatac
    51001 aaatgcaatc tatgcattca atacgatgtt tgaaaatgtt atgcaaaaag agcaaccgac
    51061 tcatgttctg gttgcgttcg atgcaggaaa aacgactttt cggacagaaa tgtatgcgga
    51121 gtacaaaggt ggaagatcca aaacacctgg cgaattcaaa gaacaaatgc catatatacg
    51181 tgatttgttg acaggactag gggtacagta ttacgaattg cccaattatg aagcagatga
    51241 tattatcggt actttggcag aaaaagtaga caaagatcaa tttgatgtcg tcgtgctttc
    51301 aggtgatcgg gatttgactc aattagctag taaagaagta aaagtggata tcactgtaaa
    51361 aggtgtcagc gatatcgaaa gctatacacc agaacatgta gcggaaaaat atgatgggtt
    51421 gacgccaaaa cagattattg acatgaaggg actagccgga gatgcctctg acaatatccc
    51481 cggtgtgact aaaatcggtg aaaaaacagc tatcaagcta ttgaaacaat atggctcagt
    51541 cgaaggaatt tatgaacata tcgatgaaat gaagcaaagc aaaatgaaag aaaatctgat
    51601 aaatgacaaa gagcaggctt tcttatcgaa aaaattggcg accatcaata cttcagcgcc
    51661 tgtggatgtc tctatcgact cattgaagta tgaagggaaa aatctcgata aactcgttcc
    51721 gttttataaa gaaatggatt tcaatcagtt cctttctaaa ttgaatatcg tagaagaaga
    51781 agtaaaaatg gatgatattt tgtttgaagt cgttcatgaa ttcaaagagg aaatgtttac
    51841 tacggatatg gcgttgtacg tggaaatgat gggcgacaat tatcatacag aggaaatcgt
    51901 cggagtagcg tgggggacag aaaagaaaat ttatgtcacg aacgatctat ctgtattcga
    51961 aaaccgagcg ttccattctt ggatcactga tccgactcgg ctgaaaaaag tatatgatgc
    52021 gaaacgaact tatgttgctt taaaccgcta tactggaaaa acgaaaggaa tcgattttga
    52081 tgtcttgcta ggtgcatacc ttctcgatac gaatgaaaaa agcacagata tcgaaggaat
    52141 agctgctcat tacggataca acgatatcca atcagatgaa gctgtatacg gcaaaggggc
    52201 gaaaaaaggt ttaccagaag aagaggaact cttttttgct catttagcgc gaaaagtagc
    52261 tgcaatcaat gcgttgacac caaaattgag ccaagaactg gcagaaaaaa accaagaaga
    52321 tcttttccgg aaaatggaac tgccattgtc tatcattttg gcagagatgg aaataagcgg
    52381 gatcaaagta gatgcgactc gcttacaaga aatgaagggc gagttctctg ctcgcttaag
    52441 agagatcgaa caaaaaatct acgaagaagc cggcgaagaa ttcaatttga attcaccaaa
    52501 gcaattagga gtgatcttat ttgaaaaaat gggattaccc gttatcaaaa aaacaaaaac
    52561 tggatattcc acagccgtag atgtactgga acagcttcgt gaacaagcac caatcgtaga
    52621 ggatatcctc acctatcgtc aaattgcaaa aattcaatct acctatgtcg agggactgct
    52681 gaaagtgatc caatcagatg gaaaagtgca tacccgttat gtccagacat tgacccaaac
    52741 aggacgatta agctctgttg atcctaattt gcagaacatc ccgattcgat tagatgaagg
    52801 gagaaagata cgtcaggcat ttgttcctag agaaaaagac tggctgattt attcttctga
    52861 ctattcacaa atcgagttac gcgtacttgc gcatatctca aatgatgaac atttgaaagc
    52921 tgccttccta gaaggtcaag atatccatgc cagcacagcg atgcgtgtat ttggaatcga
    52981 aaaggcagag gatgtcacac caaatatgcg taggcaggca aaagcagtga attttggtat
    53041 cgtgtatggc atctctgatt acggactttc acaaaatcta ggaatcagcc gaaaagcagc
    53101 acagcaatac atcgatacgt actttgaaaa atacccaggt gtcaaagaat atatggaaag
    53161 aatcgtacgc gaagcaaaag accaaggcta cgtcgaaacg ctgtatcacc gccgtcgata
    53221 tctgccagac atcaattcaa gaaattacaa tatccgttct tttgcggaac gaacagctat
    53281 caatacacca atccaaggaa gtgctgctga tattttgaaa atcgcgatga tcgaattgga
    53341 taaacgatta aaagaaacag gtcttcaagc tacgatgctg ttacaagttc atgatgaact
    53401 tgtcttcgag gtaccggaaa aagaacttga atcattagat aaattggtga aggaagttat
    53461 ggaacaagct gtttctcttc atgtaccact gatcactgac agcagttggg gaaaaacgtg
    53521 gtacgaagca aaataaacat tgtttaagac agagcaatat aatgaaggtg aaaagaaaaa
    53581 atgccagaat taccagaagt agaaaccgtt cgtaaaggat tggaacggtt agtagtagga
    53641 aaaacgattc aaaaagttca ggtcttgtgg cccaagatca tcgagcaacc agagacaccc
    53701 atctttgagg cttctcttgt tggcgaaacc atccaatcca ttggacgtag agggaagttt
    53761 ttaatttttc atctcgatca ttgtgaactg atctcacact tgcgaatgga aggaaaatat
    53821 caatttacga aagaaaatac accaatcgat aaacatacgc atgtactttt cttttttgag
    53881 gatggaagcc aacttcgcta caacgatgta cgaaaatttg gtcgtatgac aatcgtcgaa
    53941 aaaggagcaa gtgcaactta ccgaggaatc atgaaattgg gacctgagcc tttgccagat
    54001 agcttcttat tagcagattt cgcaaatgga ctgaaaaagt cccacaaagc aatcaagcca
    54061 ttgctgctag accaacgtct agtgactggt ctaggtaata tttatgtaga tgaagcatta
    54121 tgggaagcga agatccatcc agaacaaccg gcgaacacac tgcgccccaa agaggtagaa
    54181 caattacgtc tatcgatcat tgatgttttg gatcgtgcaa tagaagccgg aggtaccacg
    54241 attcgcagtt atttgaatgc attaggagaa tcaggcggat ttcaagtagc actgcatgtc
    54301 tatcagcaaa ctggcaaacc atgtatacgt tgtggaacgc cgatcgtgaa aacaaaagtg
    54361 gcacaaaggg ggacgcacta ttgtccgaat tgtcaaaggc taaaaatcgc aaagtaggat
    54421 ttgttttagg tttgacgggt ggaatagcta ccggtaaaag tacggcagcc aaagtctttc
    54481 agtctcatgg atttcctttg atcgatggcg atgtgattgc cagagaaact gttgagcctg
    54541 gaacgcttgc tctgaggaaa attgtatcag tgtttggcca agaggtattg cagcctgatg
    54601 ggcaactaga tcgagggaaa cttgggatga ttgtttttcc atcaaaggaa aaacggcaaa
    54661 aacttgatca gctattagat ccgtttatcc gaaaagcgat aaaagatcaa atcgcctctc
    54721 taagttccaa tcatccttta gtaattgtag atatcccatt gctctacgaa ggtcattatg
    54781 accactatat ggatgcagta gctgtcgttt atactacgcc agaaactcag cttcagcgtt
    54841 tgatgaaacg taatcaactg acgctagaac aagcgcagca gagaattagt agtcaacttc
    54901 caatcgaaga aaaaaagcag cgtgcggata ttttgttcga caacaatgga acaaaagaaa
    54961 aacttgtggg acaaatcgaa aattggcttt ttgctaatcg ctttctttga gtatctgtgt
    55021 caattttgct atcctgagta tatagaaagt gagggatagc gatgggatca ttaaaaaatc
    55081 aaaaggataa agtcgtaggt aacgcaaaag aaaaaatcgg cgagatgctc aataaagaaa
    55141 atctaatcga tgaaggtcgt acgcaatcag aaacagcaga agaaaaagaa aagcagtacc
    55201 aagcaagaat cgatgaaata gaagaccagc aggcagaaga agaagcgaag cggcaagatt
    55261 tgactcaaga acgaaaaaat ccgacacctg atcgtagtaa aacaccgctc ccagaaagtg
    55321 accacattcc cgatgagcaa aaaatcgagg aacagcgaat gaaacactat acaggaatcg
    55381 aagagaagtt ataaaatagt aaaaaatcga gatgtgactt gaagcagatg agaaggtgtt
    55441 catctgcttc aagttttttg tgctagatga ctaaatcagc ttttgtgtaa gttatttctc
    55501 agtaatcaag gtgatcagta ttggaaaatt gaaatttagt aaggacaggg gacacaatta
    55561 cgcatgaaag tagaaaaaat tgttcttata tccgtgtttt ttgggtagga cagtcgcgtt
    55621 tgtgatttgt ttcgtgttat aatacaacta gttgtaaaga aagacacatc ctttatataa
    55681 aatgcgatgc aagaggtgag acaaaatgag atgtcccaga tgtcaacata ataattcacg
    55741 agtaatcgac agccgtcaag cagatgatgg acgtgcgatc cgtcgccgtc gcgaatgtga
    55801 gaattgttcg ttccgattca ctacatttga acgaattgaa gctgctccgt tattagtaat
    55861 caagaaaaac ggggaacgcg aagagttcaa tcgcgataaa attttaagag gactcatccg
    55921 ttcagcagaa aaaagacctg tagctatgga acaaatggaa caaatcgtca accatgtcga
    55981 aaaccgcgta cgcagtctcg gagaaaacga agtatcgacg aatctaattg gtgaatatgt
    56041 gatggaagat ttagttgatt tagacgaaat cgcttatatt cgttttgcaa gtgtttatcg
    56101 ccagttcaaa gatatgtctg ttttcttaaa agagttgcaa gatatcgtgg ataaagcaaa
    56161 agaaaataat aaagagaata ataaagaaaa caattaagaa acaaaaagga ggcatttcct
    56221 tggaaaatgc ttggaaagag cttcaaccaa aaaatattta ccaaggaaga aaagcggctc
    56281 cgctgagaga agacagcaag aacgccttgc tgtatcttta tcagccacta atcggcggag
    56341 aagccttgag tatctatttc accctgttat cagaaatctc tcaagaatct ggcaaaggtc
    56401 ctgaagggat gcatgcagat ctgcttagta gtctaggctg cggtatcccg caattttatg
    56461 atgcaagaaa aaagctagaa ggaatcggct tactggatgt ttattttaaa gaagatagtg
    56521 atctgggacc tcgttttatt tatgagctgt tagaaccact cattcctaaa gcatttttca
    56581 aagactctgt tctggctttt cttcttctgg aaaaagttgg tgaacgacga ttccagaagc
    56641 ttacccaatt ctttgaacct aaaaggcata cagcagaggg atatcaaaaa atcacaaaaa
    56701 aatttttaga tgtttatcgc ttcaatgaag cagtgtacgc tgctaatcaa gaaaacatcg
    56761 aatcgctgaa taaatctttt gaagaatctg aatcagtagc attacttgaa gcagattcga
    56821 cattcgattg gcagtttttg aatgattggc tggcaaaaaa acatattgca agtcttgatg
    56881 atccaatcat caaacaagtc gacatgtatc atcagcttta cggtttcgat gaattgacac
    56941 ttggcgaact gatcagtcaa tcttatgact ttagtgaaca aaaagtatct gaaaaagaac
    57001 tgcaaaaagc cattttggca atgcagagac gtccggtgaa gcaaacaaaa gaaacagttg
    57061 cggtttctga aaacagtaat gaaccctcgt caaacgaaca tttgacaaac gcagcgcttc
    57121 agctgataaa agaagcacag agcattccac cgatgaaata tctggaagca atcaagtcag
    57181 aaaaaggcgg atatgtttct aaacaagaaa actggttact gcaagatctt gtttctcaat
    57241 caggtctttc cagtagcgtg atcaatgttt tgctgaatta tgtactagtg atcaagaata
    57301 atgctagctt aaatgccagt tatgtaaata cagtggcaaa tgaatgggca caaaagaaaa
    57361 tcgccacagc agaagaagcg atccagcaca ttcggcaaat aagtaatcaa gcaaaacaat
    57421 caaaacaaaa gaagcaaaca aattatcaaa ctggcaagcg aaatgttcga cgggaaaagc
    57481 ttcctgattg ggtcaaccag ccaaaagatg aaaaacagat cagcagcgag aaaaaagcag
    57541 agattgaccg ccgttttaaa gaatacctgg caaaaaagga gggtgatatc tagtggaaga
    57601 cgtaggcaaa gaattgaaga ggatcatcag caaacgcaat tatcaagaaa agtatgctga
    57661 aatgatcgct gaagtcttaa atgatgcgga tgttcaagct tttctaagcg cacaccaaga
    57721 agaattgaca caagcggata ttgaaaaaag ttacgctaaa ttgtatgaat tcgtgcaaga
    57781 aaagcgtaaa tatcaaaaaa acgatccaac gatgatcgct cccggctatg agccgaagct
    57841 gacgttgaat tttcattatg tggatgtcac ttatgtacca acggaagcat tgttagcacg
    57901 gcaaagacaa gaagaaatca gaagccgagt aaaagcaatg gatatgccaa aagatattca
    57961 atcggcttct tttgaaaact ttgaacgtac agatggacga ggatatgcga gcttagaagc
    58021 cctagatttt gtagagaaat atactgctga tccaaaaggg tatcataaag gactgtatct
    58081 agtaggaagt tttggtattg gaaaaacata tttattagga gcaacagcga gagaattagc
    58141 gattgctgga ttcaccacga cgctagtcca ttttccgaca tttgccgttg agatgaaaca
    58201 ggcaatcgga aaagatcaag tggcagaaaa gttagatgca gtgaaacgtt cacctatttt
    58261 gatgatcgat gacattggtg cagatgcgat gagtagttgg atacgagacg aagtattcgg
    58321 tgttatcctt caatatcgga tgcaggaaca gttaccaacc ttcttctcat cgaattttac
    58381 aatggatgaa ttggaacagc atttgtccgt cactcaacgt ggagatgaag agccgctaaa
    58441 agcgaaacgg ataatggaac gcatacgtta tttgacaaaa gaaatcgaaa tgactggtcg
    58501 caaccgacgc aatggttgaa cagttgacaa gtccaactga catttgacct agtagtaaaa
    58561 gcaggtcagc gaatcattat atggacagaa atgaccggag acaatcaccg caacaagtaa
    58621 tgcagaaact taaacggagg attttttatg agggctattt tttctagtat atctgtagtt
    58681 ggtctatttt ttcttttagc aggctgcggt agcgcagata gcaacacagg ttctgttgat
    58741 tcgattgatg cgggtcaaac agtaaaaaca agcagtacga aaacggagag acaaagcata
    58801 tttgtcggaa cgattgaaag tatcactcaa gtagaagcag aagaagaaac gcttcagttg
    58861 aaactcgtcg atgtcatggc caaagaagat ccagcgaata tgggaacgtc attcagcaat
    58921 gacggagtga tcttaaatgc tactgctgaa aaaataagcg tggacataaa tgaattgaaa
    58981 atcggtgaca aagtccaatt tacattagtt gagatgccga tcatgacgat gtctatccca
    59041 ccgcaagttc ctggagattc gattattgat gtttcattga acaaataacc aataacattt
    59101 tttcaaaaat aagaaaatgt tgttttatag aacgaaaagg tatatttttt aaggagatat
    59161 gggaattttt ttattcctag tctccttatt ttatttggaa aatgctataa ttatctagaa
    59221 ggagtgaagc tatgaaccat ttagatttat ctcagcgctt agccgcagtg ggtgactttg
    59281 tccctgaatc cgctcgttta gcagacattg gatcagatca cgcttactta cccgttgcat
    59341 tgatattaag aggaaaaatc gaatatgcag ttgctggtga agtcgttcaa ggtccttatg
    59401 aatcagcacg taagcaagtc aaaaaagatg gattagaaga ccgtatcacc gtacgccttg
    59461 caaatggtct agatgctatc cagccacaag atggtattac agctgtcacg attgcgggta
    59521 tgggaggttc actgatccga gatatcctag aagctggcaa gttgaatcaa cgcttaagcg
    59581 gacaagaacg tttgatcctt cagccaaaca tcggagagcg tacattacga tcttggctgc
    59641 aagaaaatca gtataaaatc caatcagaaa aaatacttga agaaaataaa aaaatatatg
    59701 aaatcattgt agccgaaaaa gaacaaaaac cagttactta caatgaaatg gagctgatgt
    59761 tcgggccatt tctgcttgaa gagaaaagtg agatcttcaa atcaaaatgg acaagagagc
    59821 ttcaacaaag aaaagctatc cgtgaacagc tcaaacaagc agctaatcaa gaggcacgtc
    59881 aaaaacaaat cgagcaggaa atccaaatga ttgaggaggt tttaaagcca tgacaatcag
    59941 cggacgcact ttcatccaaa agtttgaaag ctattgtcct cagtggctag ctgaagaagg
    60001 agacccagtc ggactgcata tcggaacatt ggataagcca atccaacgag taatgatgac
    60061 attagacgtt cgtccagaag tggtcgaaga agcaatcaag aaaaaaatcg atttgctgat
    60121 tgctaaacat cctccaatct ttcgtcctgt aaaacggctg gttactgatc agccacaaga
    60181 aaaaatgtat gcagatttgt tgaaacatga tattgccgtc tatgcagcac acacgaacat
    60241 ggatattatt tgggatggac tgaatgactg gttttgtgaa cttctcggta ttgaagtgga
    60301 gagttattta gtaaagactc atgagattca ttataaaaaa ctggccgttt atgtacctgt
    60361 ggatcatgca cagaaaatgc gtgaagtatt agctgcagct ggtgctggta cacaaggtga
    60421 ttataccggt acaagtttta cctcgattgg acacggtcga tttactccgg aagctggtgc
    60481 acaaccagcg attgggaaag tagggaagac agaacaagtt caagaggcaa aagttgaggt
    60541 tattttgccg gaaactatcg aaaaacaagt gattcaagcc atgcggtcag ctcatcctta
    60601 tgaggaacct gcttatgatc ttttcgctat agatgaacca gtcgaaatgt ttgggttagg
    60661 acgagtaggt gaattgccgc aagaaatttc tatagaggca tttgtagaac aagtaaaaga
    60721 agcgttccaa ctagatggac tgagaatagt ccagccaaaa aatgcaaaat cctctgtgaa
    60781 gcgcattgcg atttgcggtg gaagcggtga aaaattttat ccgcaagcaa tcgcccaaag
    60841 agcagatgtc tatatcacgg gagatatcta ttatcatacg gctcatgata tgcaaagcgc
    60901 tgggttgatt gcaattgatc ccggtcatta tattgaatcg ttatgcaagc aacgatttat
    60961 cgagaaattt gaatcttgga aacaagaaga aaattgggat attaactttt tcgtttctga
    61021 aacaaataca aacccatttc aatttaatta aaaggagaga atactatgta cgaaaatctt
    61081 ttgccacgtt ttttacgata tgtcaaaaca gaaacacgct ccgatgcaac aagcaaaacg
    61141 actccatcga ctcagacaca agttgctttt gcgcaagaat tgaaaaaaga attagaagag
    61201 ttaggcttag ctgatgtttt ctataatgaa gataacggat tcgttatggg aacattacca
    61261 agcaatgttg atcatgaagt gcgttccatt ggatttattt cccacatgga tacagcagat
    61321 tttaatgcag taggagtcaa tccacaaatc attgaaaact atgatggcga gtctacgatc
    61381 gtactagatg cggaagaacg ctatacattg aatacaaaag attttccaaa tttgaaaaat
    61441 tatgaaggcc acacattgat cacaacagat ggcagtacat tactgggagc agatgacaaa
    61501 tcagggattg cggaaatcat gactgcaatg gagatcttga tcaataatcc ttctatccct
    61561 cacggtacca tcaaagtggc ttttggtcct gatgaagaaa tcggtgtcgg agcggataaa
    61621 ttcgatgttg agcaattcga tgtagatttt gcttatacag tcgatggtgg tcctttaggt
    61681 gagttgcagt atgaaacgtt tagtgctgct caagcaaata ttacgatcca agggaaaaat
    61741 gtacatccag ggacggcaaa agatacaatg atcaatgctc tacagttagc aatcgatttt
    61801 cataatcagc ttccagccga tgaagttcca gaaaaaacgg aaggatacga aggtttcttc
    61861 catttgatgg cattggatgg gaatcctgaa gaagcttcta tgagttatat cattcgcgat
    61921 catgatcgtg aaaaattcga agcacgcaaa gcacaaatca cacatatcca agaagagttg
    61981 aatcagcgat ttgatcaaga acgaatcaaa gtagatatgt atgatcaata ttacaacatg
    62041 aaagaaatca ttgaaaaaga tatgagcatc gtggaattag cgaaacaagc aatgatcgag
    62101 cttggtatct ctccagtgat cgaaccagtt cgtggaggaa cagatggttc aaaaatctct
    62161 tacatgggta ttccgacgcc aaatctattt gccggaggag aaaatatgca cggacgattc
    62221 gaatttgttt ctttacaagt aatggaaaaa gcaacagacg tgattgtaaa aattgcagaa
    62281 ttgaacacaa agagttaaaa tcgaaaaaga acagcttatg acaaggcgtt cgtcccaatg
    62341 atggaatgtc atctgtctaa ggctaaaggg caggacaatg gaattggttg tcccgccctc
    62401 ttttttgaag agtaaatagg aggtaaagaa tggaaaagct gctagttttt tataacaaaa
    62461 gttcagggaa agatgagggt gagaaattag cacgctggtt tcaagattat gtaaaagaaa
    62521 agcagccaga attatatgta gaactagctg aaactggccc atcgattgat gatgcggaat
    62581 tagtcaagaa agcagaagcc atagaagctg atactttagt aattataggt ggagacggca
    62641 cgattcatca tatcgtccaa gcgttccaaa aaacattatc tcaataccat gtcggattac
    62701 ttccaggtgg aactgtcaac aaccttgcac gtgttcttga gattcccctc aaaaaagaag
    62761 aagctgctga cgtgatcctg gaaggcaatg tacggaaaat agactatggt caagtcaatg
    62821 atgaagtcat tatctctaca ctgacaatcg gaatcttagc agatacagca gtttggatca
    62881 gtcaagaaga aaaacagcgt tacggctcgt ggatctttat caagaagttt tttaagttat
    62941 tgctgaagaa gaaaaaatat catttggatt tagaaacaga cgaggagcat tggaaaggaa
    63001 aatcccaact gttgacagtc acgatgtcta actccgtggg cggttttaca aattttgacg
    63061 actcagcgac cctagatgat ggaaaatttc atgtaacgat cgtaccttcc ttagatattt
    63121 tccgatttat tttttatttg cctagaatca tgagaggcaa attctatacg atccccggca
    63181 ttacttattt cacagccaaa cgcatgaaaa tccaagcgca ggaaaaatct gtgggcactc
    63241 gaacggatgg agacacgaca gatgatcttc cagttgaatt atctgttgta tcaaaaggat
    63301 taacagttta ttcaccaaag aaagaagaaa aagcttagaa atagtagtta acagaaagtt
    63361 ggaagaagag taatggatgt attgttacac aatcctttgt ggttttacct tttcattgtg
    63421 aatttttact tattttgtct gatggggtat gataaacatc aggctagaac tagcggctgg
    63481 cgtgttcctg agaataattt gatatttgtc agcctgttag gcggtggttt gggaggattg
    63541 atctctcgaa aagttttcca tcataaaact cggaaaaaga agtttactat aggattcgct
    63601 gcaggtgtac ttgttgattt gattctcatt tattttttcc attaaggagc aggagatgtc
    63661 gtctaaagga acgaaaacta aaatcattct gaatctgctt ttgctgattg tgatttttgc
    63721 cattatttat tatttaatca atcaatcatt tgcagatatc tttgccgaat tgctgtctac
    63781 cagtgttgtt gttttggcag cggctgttat attagggaca gtttaccaaa tcgctgaagg
    63841 gcgctcaatc aaagaaattg ctgaaccttt cgcgccgaat tttacaacga aagatgggtt
    63901 cttgacctct agctatattg cgttttaccg aatcgtttcg tttggtacag gaacgctgat
    63961 ctcggagatt tatttttata acaaaaaagg aatgaagcta tcccagggag caggggtgac
    64021 agcactccat atgattatgt acaaactggc agtgatcact tatgcattag ctggcttggt
    64081 catccaattc tctctttttt attctaatgg tccatcaatg atctggttta tcatcgctgg
    64141 tatccttttg acgatcgtga ttgttgcctt tttattggcg atgtccgtca gcttgaatgt
    64201 tcaaatattt tttgtcagct tatcgaataa gttatttaaa agtgagcgtt tgcggaaatg
    64261 ggtggataca tgcaatcagc agatctactc tttaagggaa acggtccaaa ccattatcca
    64321 agacaggact gcgctattgc ggatttatct atggaatatg ttaaaacttg tattttggta
    64381 tgtacttcct tatttgattc tgattgaaaa ccatcctaaa atagattttc tactgaccat
    64441 ttcgtttatc agctttgcag tagtgctttc aggggttatt cctacgcctg ctggtattgg
    64501 ttcctttgaa tttgtctatt tgttattatt cagaccagtt gttggaacag ttgacgcagt
    64561 ttcttcgctt ttactgtatc gtttcagttc ctttatcttg ccatttctct atggatttgt
    64621 gtatgtgatt gctgaacggc gaagagtgat caaagaagaa ataatagaag taaaaaaaga
    64681 gaataaagaa aatcaagggt aggtctttta taagatctac cctttttatc aaatcaaaga
    64741 aaaacgttat ggataagata attttacgtt tgtttggctc tttttttata tacatacaat
    64801 caattttgtt tttttaagat ttatataagt cgagaaaaaa agtcaaaaaa ctatgtgtat
    64861 attttgacca aaattgacca aagcgatata atagtttttg taaagatcaa agaaataagt
    64921 gatcttacct ttaattagga gggtatacct gtatgaatat tgagaaaatg actacgacgc
    64981 ttcaagaagc gattgctgaa gctcaacaga ttgcggtcac tcgaaaacat caagatatcg
    65041 acattgccca tgtatggaaa atctttttac aatctaatca ttttggtcga aatttctata
    65101 cggatgccgg attggatgtc gaatcttttg aacatgaaat tgatcgtcta ctggatgagt
    65161 atccagttgt ttctggtgga aacgtccaat atggacaaaa cctcagccag aatttctttc
    65221 gattattgaa tgaagcagac caaatacgtg aaagcttcgg cgacgagttt ctttcaacgg
    65281 aagtcgttat tttagcgttg atgaaattaa aaaattatcc gttaactgtt tatttgaata
    65341 aaaacggatt atctgaaaaa gaattgcgta aaaacatcga agagatgaga ggaggagaaa
    65401 gagtgacctc acaaaaccaa gaagaacaat acaaagcatt agaaaaatac ggcgttgatt
    65461 tagtacagca agtcaaaagc ggaaaaatgg atccaatcat cggtcgtgat gaagaaatcc
    65521 gtgatgtcat ccgtattctt tcacgaaaaa caaaaaataa tcctgttctg ataggagaac
    65581 ccggtgtagg gaaaacggca atcgttgaag ggcttgctca acgtatcgta cgcaaagatg
    65641 tgcctgaaaa tttaaaagat aaaacgattt tttcattaga tatgggtgca ttgatcgctg
    65701 gagcaaaatt ccgtggtgaa tttgaagaaa gactaaaagc agtcttgaaa gaagtcaaaa
    65761 aaagtgatgg acgtatcctc ttgttcatcg atgaaatcca caatatcgta ggggcaggaa
    65821 aaacagaagg aagtatggat gccggaaatc tgttgaaacc aatgcttgct cgcggtgaat
    65881 tacatttgat cggtgccaca actttagatg agtaccgtca atatatggaa aaagacaaag
    65941 cgttggaacg tcgctttcaa aaggtattag tcaaagaacc aacagtggaa gatacgatca
    66001 gtattctgcg tggattaaaa gaacgttttg agatccacca tggtgttaac atccatgaca
    66061 acgcattagt agcagcagct actttatctg accgttatat tactgatcgg ttcttaccgg
    66121 acaaagcaat cgatttgatc gatgaagcca gtgcaacgat tcgggtagaa atgaactcta
    66181 tgccaacgga attagatcaa gttactagac gtttgatgca gttggaaatc gaagaagctg
    66241 cactgaaaaa agaatcagat gatgcaagta aaaaacgctt gaaaaatttg caagaagaat
    66301 tagctgaact tcgtgaagaa gcaaatgcga tgaagatgca gtgggaaaca gaaaaagaag
    66361 aagtcaattc tgtttcagca aaacgtgctg aaatcgataa agcaaaacac gaattagaag
    66421 atgcagaaaa taactatgat ttagaacgcg ctgctgtatt gcgtcatggt acgatacctc
    66481 aattagaaaa agaattgaag gaattagaag ctaaagcaaa agacagcgag attaagatgg
    66541 ttcaagagtc cgttaccgaa aatgagattg ctcaagtcgt tggcagatta acgggtatcc
    66601 ccgtaacgaa acttgtagaa ggtgaacgag aaaaactaat taaattgaat gaaacacttc
    66661 ataaacgagt gattggtcaa gatgaagcag ttgatgcggt cagtgacgcg gtaattcgtt
    66721 cacgggctgg attgcaagac ccaaatcgtc ctctaggttc tttccttttc ctaggaccaa
    66781 ctggtgtcgg aaaaaccgaa ttagcgaaag cgttagctga gaacttgttt gactcagaag
    66841 atcatatggt acggatcgat atgagtgaat atatggaaaa acatgctgtg tctcgtctag
    66901 tcggagctcc tccaggctat gtaggttacg aagaaggtgg tcaattaacg gaagctgtca
    66961 gacgaaatcc ttatacaatc gtcttgttgg atgaaatcga aaaagcgcat cccgatgtct
    67021 tcaatatctt gttacaagtc ctagatgacg gacgcttgac tgattcaaaa gggcgagtag
    67081 tagatttcaa aaatacggtt ctgatcatga ccagcaatat cggttcacag ttactgctgg
    67141 aaggcgtgac tgctgatgga acgattccag aagcagtggc tgaacaagtc aacacgctat
    67201 tacgtggaaa cttcaaacca gaattcttga accgaatcga cgacacgatt ttatttacac
    67261 cattgagcct agacaacgtg aaaggaatcg ttgacaaaat ggtggcgcaa ttggcacaac
    67321 gtctggaaca tcaagaaatc ctgctgacaa tcagtgatga agccaaaacg tggattgctg
    67381 aaaatgctta tgaaccagca tatggtgcaa gaccattgaa acgatttatc actaaggaag
    67441 tagaaacacc actagctaaa gaaatcgttg caggacatgt tatgcctaaa tcaaaagtaa
    67501 cgattacttt acttgatgga caacttcatt tcaaaacaga agagctagaa gaaatcgtct
    67561 aatcttccat tgagactata aaagaaaaaa ggggtctgac acaactagtg tcagacctcc
    67621 ttttttcaaa taaacagtgt tccagaagta gtttcttcga aaaataagcc gaaatttctt
    67681 gaagctgccc gcttctgtca caacctcttt tattaggtat ttttcacttt ttctaattta
    67741 taactttcaa agtaacgctc atctttttta ctttgagacc atgcaaacaa tcccattaag
    67801 gcagcaccta tcgtatttgt cagcaagtcg cccatcgtat ccatcaatgc tgctcgtccg
    67861 acaaacagtg tgccatcaga agcagcaaaa cgttgaagat tcatgcctaa gaactggtcg
    67921 cataagaatt cccagaactc ccaaaacacg ccgcaaagtc cagcaaacgc aaagccgaat
    67981 aagaggaaca accaaggact ggtttttgat atctcagcat ctttcatcaa gtaaccaatc
    68041 aatccatagc caagagctgt caggaccatt ggactcaccg catgtaagat tttgtcccaa
    68101 aaagagatga tactgatcaa atgcatccct gtgcctaaaa agacagagat gaacaagaaa
    68161 aaccagtaaa acaaaacgat tgctgctggt attttaagtt tgaaaacttt caaaatgact
    68221 tgtggcatga aaatcaatgc aatccctaat aaagattcca cgataaatgt gattccttga
    68281 gaagtcgaat atttttgtgt gataaattca taaaaattat agcagacaac gaatacacca
    68341 aaagcaagta aagctatttg cacctttttg atttctttaa tcactgaaag tccctccatc
    68401 taaaaatctt tttacttctg aaagcaactc aatttctgaa gaaaccactt ttccgttcaa
    68461 tttgatcaaa cctattgtat ataagttcag gtagtgaaat tgattttcag ctgtttcttg
    68521 tagtgcagcg atttttttcg ggtgggttcc gccttgctgt cgagtatcag tatataagcc
    68581 gatcactggg atgcctttcg cataagccac accgatttcc gatgctaccc cggcatcgat
    68641 cgtcagccca tctagtaaag caatcattaa atcactagcc aacacttttt ctgtgtcagc
    68701 aagagcaatc attcgactgt ctgcataagc agttttgtca ttgattgctt cattttcttg
    68761 aggaagatag atcgaaagct cagaagagag ctctctgatt tctttaacta actgttggtt
    68821 atataacaaa tcacttttag caaacattgg tgcggcaaaa taaattttca tctaaacatc
    68881 atccttttta tcaaaaataa tcgctaaagt aagcttccat gtttggaatg atacgctcta
    68941 gtgacttcag tgtttcttca tctgtttcta accgttcgat tcttgccaaa taagaagcac
    69001 ggcgataatt catcatcaag caagtcaatg tttggatatc cagtcgaacg gattttccta
    69061 taggttcatt taagacacgg acttgtccct gttcatccca tgttaaagcg aagacaccat
    69121 tattccaagg agcgacagga tcttcaatga tgaaatgaaa agcatcagct gttccaacaa
    69181 acggaaaccg ttgaaggaat tcttttacat caacgatccg agccataaaa tatggttcga
    69241 tctgctcttt gatctgacta tcttcaatca aaaatgctaa aggctcattt ttataaatat
    69301 ctccatgtac ccagtagatc atggaaaaat gtgcggaaat aaagttccat aagccatttc
    69361 gagcttcttg atcaagatag aacatttctt ttacgtgaaa tatttcttca gctacccagt
    69421 agaacagaac acctcttggt tcatggttgc tatcgtagta gacagcggct gtgcgctcat
    69481 cttcattttc gaaacgccaa tactcttccc aatgaaaatc actgcggaat aaagcaccat
    69541 ggttttgttg ggcaaatttg tcataaacgg aaaatacgtc tggatgatca actggtaatc
    69601 gctcaaccat accacttact gggatttgtt taggtagctg tgtatctctg attttaaagg
    69661 aaagtttatc agacatgatt tcccatcctt tacgccgata gtaggggata ctgtaaggat
    69721 acaaataaga gatccattgc ttattcttgc gcatattatc caatgcaacg ataattagat
    69781 cttgcatcaa tccatggtta gcatattctg gataagttcc aactccagtc acaccaccca
    69841 ttttataacg tgcaccgtga atattgactt cacaaggata gatagcgatt tgagagatca
    69901 gtttattttc gtggaaccat ccgaacactt tcgatacttc caaaatcggt tttttggaac
    69961 ggataaaagc tcgtttattc tcaaacccgc tttcctcgat gtctgcttca gtcacttgga
    70021 acacatagga aagcaattca ttgaattgat cgatatgttc ttgagtgacc ggttttaatt
    70081 caagattttc tctaaaatct ttttgatcca ttttttcatc tccatttatt agcttgataa
    70141 cagtatagca aaattctaca aaaaaaactt ctatagctga ctaattaaaa actctttaaa
    70201 ttactgcttt tcgttggtat aatggaaagt gctgattata tgaaaagagg agacgctatg
    70261 gatataaaga aaatgaaaga acgccaagag cagattcgta atttttcgat catcgctcat
    70321 atcgaccatg ggaaatctac attggccgat cgtattttag aaatgacgca cactgtgacg
    70381 tctcgcgaaa tgcaagatca gctgttagac tcgatggatt tggaacgtga acgtggaatc
    70441 acgattaaat taaatgctgt agaactcaat tacacagcga aaaatggaga aacatatatc
    70501 tttcacttga ttgacacccc agggcacgtc gacttcacct atgaagtctc tcgaagcctt
    70561 gctgcctgtg agggtgccgt tttagtggtc gatgcagcac aaggaatcga agcacaaaca
    70621 ttggccaatg tttatttagc gttagacaat gatttggaga tcctgccagt catcaataaa
    70681 atcgacctac ccgcagcaga tcccgaacgt gtccgtcaag aaatcgaaga cgtaatcgga
    70741 atcgatgcta gtgaagctgt attagccagt gccaaatcag ggattgggat tgaagatatt
    70801 ctcgagcaga tcgtggaata tgttcctgca ccaagtggag acttagatgc accgctaaaa
    70861 gctttgatct ttgactctat ttatgatagt taccgcggtg ttgttctaaa tgtccggatc
    70921 acggacggta tggtcaaacc cggagacaaa atcaaactga tgagtaatgg caaaacattt
    70981 gatgttacag aggtcggggt cttctcgcca aaagcagttg ctagagactt tttgatggtc
    71041 ggtgatgtcg gttatatcac agcaagtatc aaaactgtcc aagatacacg agtaggggat
    71101 acagtaacgt tagcagacaa tcctgccgct gaagctttac caggttaccg aaaaatgaat
    71161 ccgatggttt attgtggtct ttatccaatt gatacttctc gttacaacga tttgcgggaa
    71221 gctttagaaa aactgcaatt gaatgatgct gctttacaat tcgaaccaga aacctctcaa
    71281 gcattaggtt ttgggttccg ctgtggattc ctcggacttc ttcatatgga tgtcgtccaa
    71341 gaacgcttgg aacgggaatt caatctagaa ttgatcacga ctgcaccatc cgttatttac
    71401 catgttaata aaacggatgg tacgactgct acagtagata acccggcaga ttttcctgaa
    71461 cctgtaacga ttcaggatgt agaagaacca ttcgtcaaag cacagatcat ggtcccaaat
    71521 gattttgtcg gtgcagtaat ggaactttct caacgaaaac ggggagaatt cattacgatg
    71581 gattatttag atgattaccg agtaaatgtc gtctataata ttccgctttc tgaaattgtc
    71641 tttgactttt tcgacaaatt gaaatcaagc acgaaaggct atgcctcatt ggattatgaa
    71701 atgtctggtt atcaaaaaag caagttagtg aagatggaca tcttgctgaa tggagaaaaa
    71761 gtcgatgcat taagctttat cgttcaccga gactttgcct atgaacgtgg aaaagcaatc
    71821 gttgaaaaac tgaaaaaact aatcccacgc caacaatttg aggtgccaat ccaagcagct
    71881 attggacaaa aaatcgttgc ccgttcagac atcaaagcct tgcgtaaaaa cgtcttggct
    71941 aaatgttatg gtggagatgt ttctcgtaaa cgtaaactct tagagaaaca aaaagaaggg
    72001 aagaagcgga tgaaacaaat cggctccgtc gaagttccgc aagaagcctt catggccgtt
    72061 ctgaaaatgg acgaggacga accgaagaaa tagcaagggt ttgtttgaaa acagtgtaaa
    72121 aaataaacca tgtttacatg gatttgccac cggtttgcca ccggtggttt ttttcggtgg
    72181 caaaaatcaa gaattctttc taagattttc catgatatcg accgtttcat ttctcatctt
    72241 atctgttaca tgcgagtaag tatccatcgt aattgaaatt ctgctgtggc ccaatcgttc
    72301 agagatttct ttcatttttg cgccattttc gagaagaagt gtagcatgag tatgtctgag
    72361 agaatggaag ttaaaagaga gggagagtgc attcgatatc ctcctagtat tccatttcac
    72421 tacacttggc gtaactagct caccgtcttc cttcgtacat actgtatttg aatcaatgta
    72481 gagctttcca tacttcattc gattttctaa ttgttgtttc ttatgttttt tcagaattgc
    72541 tagcaaggtt tgtccaataa aaatcgttcg attggaactg cttgtctttg gcgtaccata
    72601 tacccatgcg ccgtcattct ttaccatttg tttctctaca gtaattgttc catttgaaaa
    72661 atcgacatca tcccacgtca gaccacaaac ttcgccaacg cgcattcccg tataaaatcc
    72721 aatattcaaa ggaatataga aaggatgtcc ttcaggagta atttctagca tatgatcaaa
    72781 gtcctcaaga gaaatgattt ttagatcttt tttagtcgtt ggtcgtgctt catattttgg
    72841 tatttttaca tacagcatag gattttgctt gattaatccc caaggataaa ccgccatatt
    72901 cagcgcattc ttaaggacag agtgagtaat agtcattgtt ttcttcgagt aacccttttt
    72961 aaattcagca ttgatgaaat tttgtaaaag agcaggggag agatccgtaa gttttttctt
    73021 tcctaaataa ccgtttatat gatttttgat ggtaaatcgg tagttttcat aggtattgta
    73081 ttttagattt agtttaacgt attcctccat ccaaaaatca aggtattgtt ttactcgagt
    73141 atccgtacct aaaaagtatt gtcctgtttc gtcaatatct gataaaactt ttcgtaaagc
    73201 agcttcggcc tctggtcggg tgtctccgcc aactttctcc actttttttc ttgagccatc
    73261 atcattgata tcttcgccgt ttgtataatt aagcgagaca aataaaaaag ccatttatgt
    73321 tacactc
//
LOCUS       DACCVZ010000004        63821 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.004, whole genome shotgun sequence.
ACCESSION   DACCVZ010000004 DACCVZ010000000
VERSION     DACCVZ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 63821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63821
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.004"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(21..1643)
                     /locus_tag="IVW63_000238"
     CDS             complement(21..1643)
                     /locus_tag="IVW63_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7858542.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            1892..2413
                     /locus_tag="IVW63_000239"
     CDS             1892..2413
                     /locus_tag="IVW63_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858543.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(2599..4329)
                     /gene="spxB"
                     /locus_tag="IVW63_000240"
     CDS             complement(2599..4329)
                     /gene="spxB"
                     /locus_tag="IVW63_000240"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HAP7858544.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            4494..5312
                     /locus_tag="IVW63_000241"
     CDS             4494..5312
                     /locus_tag="IVW63_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAP7858545.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(5415..5612)
                     /locus_tag="IVW63_000242"
     CDS             complement(5415..5612)
                     /locus_tag="IVW63_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858546.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            5781..6359
                     /locus_tag="IVW63_000243"
     CDS             5781..6359
                     /locus_tag="IVW63_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAP7858547.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            complement(7404..7907)
                     /locus_tag="IVW63_000244"
     CDS             complement(7404..7907)
                     /locus_tag="IVW63_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP7858548.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            8266..9291
                     /locus_tag="IVW63_000245"
     CDS             8266..9291
                     /locus_tag="IVW63_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP7858549.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            9614..10492
                     /locus_tag="IVW63_000246"
     CDS             9614..10492
                     /locus_tag="IVW63_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858550.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            10968..11084
                     /locus_tag="IVW63_000247"
     CDS             10968..11084
                     /locus_tag="IVW63_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAP7858551.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            12012..12350
                     /locus_tag="IVW63_000248"
     CDS             12012..12350
                     /locus_tag="IVW63_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858552.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            12444..12674
                     /locus_tag="IVW63_000249"
     CDS             12444..12674
                     /locus_tag="IVW63_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858553.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            13074..13445
                     /locus_tag="IVW63_000250"
     CDS             13074..13445
                     /locus_tag="IVW63_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAP7858554.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(13719..14411)
                     /locus_tag="IVW63_000251"
     CDS             complement(13719..14411)
                     /locus_tag="IVW63_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP7858555.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(14414..15199)
                     /locus_tag="IVW63_000252"
     CDS             complement(14414..15199)
                     /locus_tag="IVW63_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP7858556.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            15436..16836
                     /gene="lacG"
                     /locus_tag="IVW63_000253"
     CDS             15436..16836
                     /gene="lacG"
                     /locus_tag="IVW63_000253"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAP7858557.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            16861..17178
                     /locus_tag="IVW63_000254"
     CDS             16861..17178
                     /locus_tag="IVW63_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP7858558.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            17191..18864
                     /locus_tag="IVW63_000255"
     CDS             17191..18864
                     /locus_tag="IVW63_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7858559.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            18878..20509
                     /locus_tag="IVW63_000256"
     CDS             18878..20509
                     /locus_tag="IVW63_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-1,4-beta-galactosidase"
                     /protein_id="HAP7858560.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(21000..22565)
                     /gene="guaA"
                     /locus_tag="IVW63_000257"
     CDS             complement(21000..22565)
                     /gene="guaA"
                     /locus_tag="IVW63_000257"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAP7858561.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(22624..23547)
                     /locus_tag="IVW63_000258"
     CDS             complement(22624..23547)
                     /locus_tag="IVW63_000258"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAP7858562.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            23743..24348
                     /locus_tag="IVW63_000259"
     CDS             23743..24348
                     /locus_tag="IVW63_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7858563.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            24656..25672
                     /locus_tag="IVW63_000260"
     CDS             24656..25672
                     /locus_tag="IVW63_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7858564.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            25813..27114
                     /locus_tag="IVW63_000261"
     CDS             25813..27114
                     /locus_tag="IVW63_000261"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAP7858565.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            27160..27822
                     /gene="deoC"
                     /locus_tag="IVW63_000262"
     CDS             27160..27822
                     /gene="deoC"
                     /locus_tag="IVW63_000262"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAP7858566.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            27843..28241
                     /locus_tag="IVW63_000263"
     CDS             27843..28241
                     /locus_tag="IVW63_000263"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAP7858567.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            28307..29389
                     /locus_tag="IVW63_000264"
     CDS             28307..29389
                     /locus_tag="IVW63_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7858568.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            29601..31163
                     /locus_tag="IVW63_000265"
     CDS             29601..31163
                     /locus_tag="IVW63_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7858569.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            31156..32289
                     /locus_tag="IVW63_000266"
     CDS             31156..32289
                     /locus_tag="IVW63_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7858570.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            32289..33245
                     /locus_tag="IVW63_000267"
     CDS             32289..33245
                     /locus_tag="IVW63_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7858571.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            33344..34510
                     /gene="deoB"
                     /locus_tag="IVW63_000268"
     CDS             33344..34510
                     /gene="deoB"
                     /locus_tag="IVW63_000268"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAP7858572.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            34534..35352
                     /locus_tag="IVW63_000269"
     CDS             34534..35352
                     /locus_tag="IVW63_000269"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAP7858573.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            35369..36076
                     /gene="deoD"
                     /locus_tag="IVW63_000270"
     CDS             35369..36076
                     /gene="deoD"
                     /locus_tag="IVW63_000270"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAP7858574.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(36374..37060)
                     /gene="gpmA"
                     /locus_tag="IVW63_000271"
     CDS             complement(36374..37060)
                     /gene="gpmA"
                     /locus_tag="IVW63_000271"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAP7858575.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(37232..37813)
                     /locus_tag="IVW63_000272"
     CDS             complement(37232..37813)
                     /locus_tag="IVW63_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7858576.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(37946..38629)
                     /gene="rpiA"
                     /locus_tag="IVW63_000273"
     CDS             complement(37946..38629)
                     /gene="rpiA"
                     /locus_tag="IVW63_000273"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAP7858577.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            38948..39361
                     /gene="rpsL"
                     /locus_tag="IVW63_000274"
     CDS             38948..39361
                     /gene="rpsL"
                     /locus_tag="IVW63_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAP7858578.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            39445..39915
                     /gene="rpsG"
                     /locus_tag="IVW63_000275"
     CDS             39445..39915
                     /gene="rpsG"
                     /locus_tag="IVW63_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAP7858579.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            40009..42096
                     /gene="fusA"
                     /locus_tag="IVW63_000276"
     CDS             40009..42096
                     /gene="fusA"
                     /locus_tag="IVW63_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAP7858580.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            42268..43455
                     /gene="tuf"
                     /locus_tag="IVW63_000277"
     CDS             42268..43455
                     /gene="tuf"
                     /locus_tag="IVW63_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP7858581.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            43862..44170
                     /gene="rpsJ"
                     /locus_tag="IVW63_000278"
     CDS             43862..44170
                     /gene="rpsJ"
                     /locus_tag="IVW63_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAP7858582.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            44201..44830
                     /gene="rplC"
                     /locus_tag="IVW63_000279"
     CDS             44201..44830
                     /gene="rplC"
                     /locus_tag="IVW63_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAP7858583.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            44858..45481
                     /gene="rplD"
                     /locus_tag="IVW63_000280"
     CDS             44858..45481
                     /gene="rplD"
                     /locus_tag="IVW63_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAP7858584.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            45481..45771
                     /gene="rplW"
                     /locus_tag="IVW63_000281"
     CDS             45481..45771
                     /gene="rplW"
                     /locus_tag="IVW63_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAP7858585.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            45810..46643
                     /gene="rplB"
                     /locus_tag="IVW63_000282"
     CDS             45810..46643
                     /gene="rplB"
                     /locus_tag="IVW63_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAP7858586.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            46686..46964
                     /gene="rpsS"
                     /locus_tag="IVW63_000283"
     CDS             46686..46964
                     /gene="rpsS"
                     /locus_tag="IVW63_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAP7858587.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            46987..47334
                     /gene="rplV"
                     /locus_tag="IVW63_000284"
     CDS             46987..47334
                     /gene="rplV"
                     /locus_tag="IVW63_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAP7858588.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            47348..48004
                     /gene="rpsC"
                     /locus_tag="IVW63_000285"
     CDS             47348..48004
                     /gene="rpsC"
                     /locus_tag="IVW63_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAP7858589.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            48007..48441
                     /gene="rplP"
                     /locus_tag="IVW63_000286"
     CDS             48007..48441
                     /gene="rplP"
                     /locus_tag="IVW63_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAP7858590.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            48431..48619
                     /gene="rpmC"
                     /locus_tag="IVW63_000287"
     CDS             48431..48619
                     /gene="rpmC"
                     /locus_tag="IVW63_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAP7858591.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            48644..48910
                     /gene="rpsQ"
                     /locus_tag="IVW63_000288"
     CDS             48644..48910
                     /gene="rpsQ"
                     /locus_tag="IVW63_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAP7858592.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            48968..49336
                     /gene="rplN"
                     /locus_tag="IVW63_000289"
     CDS             48968..49336
                     /gene="rplN"
                     /locus_tag="IVW63_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAP7858593.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            49373..49681
                     /gene="rplX"
                     /locus_tag="IVW63_000290"
     CDS             49373..49681
                     /gene="rplX"
                     /locus_tag="IVW63_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAP7858594.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            49709..50248
                     /gene="rplE"
                     /locus_tag="IVW63_000291"
     CDS             49709..50248
                     /gene="rplE"
                     /locus_tag="IVW63_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAP7858595.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            50267..50452
                     /locus_tag="IVW63_000292"
     CDS             50267..50452
                     /locus_tag="IVW63_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAP7858596.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            50488..50886
                     /gene="rpsH"
                     /locus_tag="IVW63_000293"
     CDS             50488..50886
                     /gene="rpsH"
                     /locus_tag="IVW63_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAP7858597.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            50918..51454
                     /gene="rplF"
                     /locus_tag="IVW63_000294"
     CDS             50918..51454
                     /gene="rplF"
                     /locus_tag="IVW63_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAP7858598.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            51615..51971
                     /gene="rplR"
                     /locus_tag="IVW63_000295"
     CDS             51615..51971
                     /gene="rplR"
                     /locus_tag="IVW63_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAP7858599.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            51992..52492
                     /gene="rpsE"
                     /locus_tag="IVW63_000296"
     CDS             51992..52492
                     /gene="rpsE"
                     /locus_tag="IVW63_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAP7858600.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            52507..52686
                     /gene="rpmD"
                     /locus_tag="IVW63_000297"
     CDS             52507..52686
                     /gene="rpmD"
                     /locus_tag="IVW63_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAP7858601.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            52730..53170
                     /gene="rplO"
                     /locus_tag="IVW63_000298"
     CDS             52730..53170
                     /gene="rplO"
                     /locus_tag="IVW63_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAP7858602.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            53170..54465
                     /gene="secY"
                     /locus_tag="IVW63_000299"
     CDS             53170..54465
                     /gene="secY"
                     /locus_tag="IVW63_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAP7858603.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            54527..55174
                     /locus_tag="IVW63_000300"
     CDS             54527..55174
                     /locus_tag="IVW63_000300"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAP7858604.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            55365..55583
                     /gene="infA"
                     /locus_tag="IVW63_000301"
     CDS             55365..55583
                     /gene="infA"
                     /locus_tag="IVW63_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAP7858605.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            55616..55732
                     /gene="rpmJ"
                     /locus_tag="IVW63_000302"
     CDS             55616..55732
                     /gene="rpmJ"
                     /locus_tag="IVW63_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAP7858606.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            55750..56115
                     /gene="rpsM"
                     /locus_tag="IVW63_000303"
     CDS             55750..56115
                     /gene="rpsM"
                     /locus_tag="IVW63_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAP7858607.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            56143..56532
                     /gene="rpsK"
                     /locus_tag="IVW63_000304"
     CDS             56143..56532
                     /gene="rpsK"
                     /locus_tag="IVW63_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAP7858608.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            56612..57550
                     /locus_tag="IVW63_000305"
     CDS             56612..57550
                     /locus_tag="IVW63_000305"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAP7858609.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            57578..57958
                     /gene="rplQ"
                     /locus_tag="IVW63_000306"
     CDS             57578..57958
                     /gene="rplQ"
                     /locus_tag="IVW63_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAP7858610.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            58230..59069
                     /locus_tag="IVW63_000307"
     CDS             58230..59069
                     /locus_tag="IVW63_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP7858611.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            59045..59914
                     /locus_tag="IVW63_000308"
     CDS             59045..59914
                     /locus_tag="IVW63_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP7858612.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            59904..60701
                     /locus_tag="IVW63_000309"
     CDS             59904..60701
                     /locus_tag="IVW63_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAP7858613.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYCVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            60904..61650
                     /gene="truA"
                     /locus_tag="IVW63_000310"
     CDS             60904..61650
                     /gene="truA"
                     /locus_tag="IVW63_000310"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAP7858614.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            62315..62552
                     /locus_tag="IVW63_000311"
                     /pseudo
     CDS             62315..62552
                     /locus_tag="IVW63_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(62696..63472)
                     /locus_tag="IVW63_000312"
     CDS             complement(62696..63472)
                     /locus_tag="IVW63_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP7858615.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            63595..>63821
                     /locus_tag="IVW63_000313"
     CDS             63595..>63821
                     /locus_tag="IVW63_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAP7858616.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNL"
BASE COUNT        20239 a        11400 c        13473 g        18709 t
ORIGIN      
        1 tttttaagct aaataggcca ttatgcccat aactcgttca attgtttttg aatatctgca
       61 ttttccaaaa attcatcata tgtcgtatca gctcgatcga tcacaccttt atccgaaacg
      121 gcaatgatgc ggtttgccaa tgtttggata aattgatggt catgtgacgc aaataagatt
      181 gagccagtaa atgccatcaa gccgtcattc aatgctgtga ttgattctaa gtctaaatgg
      241 ttcgttggat catctaatac aagtacgtta gctttcgaaa gcatcatttt tgaaagcatg
      301 caacggactt tctctccacc agataaaaca ttcactggtt tcaatacttc ttcaccagaa
      361 aacaacattc ttcctaagaa gcttcttaag aaggtgttat catcttcttc tttacttgca
      421 tattgacgca accagtctaa aatcgttaga tcagtatcga attctttcgt tgtatccttt
      481 ggtaaataag aattacttgt tgtcacaccc caacgtactg ttccagtatc tggcgtaatt
      541 tcacccatga taactttgaa tagcgttgtt gttgttatat cattttctgc gacgaaagcg
      601 accttgtctt ctttgctcaa attaaaagat atatcatcta aaattttctt tccatcaatc
      661 gttacactta cattttctac ctgcaataag tcgtttccaa tctcacgttc aggtttgaat
      721 ccaacgaatg gataacgtct agaagaaggt tggatatcgt ctaaagtaat tttttcaagc
      781 atttttttac gtgaagttgc ttgttttgat tttgatgcat tcgcactaaa gcgggcaata
      841 aattcttgga gttctttgat ttgttcttct tttttggcat ttgcgtttgc ttgaagttta
      901 gccgctagtt gactagattc caaccaaaaa tcataatttc ctacataaag tttgatttta
      961 ccaaaatcta gatccgccat atgtgtacat actttgttca aaaagtgacg gtcatgggat
     1021 acaacgatca cagtattttc aaaattgatc aaaaattctt ccagccaatt gatcgattgg
     1081 atatccagac cgtttgttgg ttcgtctagc aaaagaacat caggtttacc aaatagtgtt
     1141 tgtgctaata acacttttac cttttgtcca ccagttaatt cactcatttg ctgatggtgc
     1201 aattcttcag ggatgttcag accttgcagt aaaacagctg cttctggttc agcttcccat
     1261 ccattaagct cagcaaattc tccttctaat tcagctgctc gaataccatc ttcgtcagtg
     1321 aaatcctctt tcatgtaaat cgcatctttt tctttcagca cttcatacag acgcttgtgt
     1381 cccatgatga ctgtttcaag tacagtatag tcttcatagt cgtaatggtt ctgtttcaat
     1441 acggccatcc gttcatctgg tcccatagta acggaacctg tggaaggctg cagatcccct
     1501 gataacactt taaggaacgt tgatttacct gcaccatttg caccaatcaa gccatagcag
     1561 tttccggggg taaatttaat attcacatca tcaaatagtt tgcggtctga aaagtgcaaa
     1621 ctcacatcat ttacagtaat caattttttt cctcactttt atcattatta gttttgacaa
     1681 gtcttataga attatatagg ggaaaggtaa aagattcaag gcaatcgaac attctttgtg
     1741 tttcacgtga aacagaatga aaaaaataaa aataaaagcg gagcgaaaat agctactata
     1801 ggatttatta gtttgcaaca gcataatttt tgacgttatt tataagaggg agtactataa
     1861 aactgtaaaa gaaatgaaag aaggattgaa aatggatgaa aaaagaacca tcgactgggg
     1921 ctcattgatt ttgggaattt tatttgtact tgtctcattg ttatcatttc aagaccctgt
     1981 cggaaattta gttgcaattg tagtagtctt tgcgattttt gcctttatta aagggatatt
     2041 tgaactgttt gtacggaaca gattaaaaga gctaacagga tataaaggaa agatgccctt
     2101 aataatcggg atcatcgata ttctagttgg cgtctttttc ttattcaata ttggtgcagg
     2161 agtcgcagca ttgccttttg tttttgcagt atggtttatt gctgattcag ttttagcgtt
     2221 atttactgct gacttggcaa gaggagtaag tgaaggatat tattggttta cgatcatcgt
     2281 caatatttta ggaattttat taggaatttt cttattgttt aatccaattt cttctgcgtt
     2341 gacattaagc tttttagttg gattctattt tatgttattt ggtatcacac atatcgtcta
     2401 tgcatttaga taagtaaaat caaacaaata aaaaagccgg cttccgatta cagttttact
     2461 gttgtaattg gaagccggct tttttatcat ggacaaatat gcacgaggtg atttttaggt
     2521 gtcgagacaa atttatgcaa aaatgtgaga agctatatac acaaatttta tcttaatact
     2581 cgaagcatag cgcagttgtc acaacctctt ttcatataat tcattcaata ctggcaaatc
     2641 atggacttca tatttttctt tgaatgcttg gatttcttct tcagaatatt ttcttggatc
     2701 taaatgcaga tcttctactg gcaatgggcg cttgttattg atcttcacat cgattactac
     2761 aggacgatct gattttgcag ctgcatcaaa ggcaaatcga agttgcgagt attctgtgac
     2821 tgtaaagcta tttgccccga gcgcttctcc aactttaccg aaatctgcat cttctaaaaa
     2881 tacaccaaat ttcttttgtt ccgtatcttc ttgttctgct tcgatgaaac caaaagaatc
     2941 attcgaaaag acaacattaa taattggaag ctgatatttg acttgtgtaa tgatatcttg
     3001 catgaccata gcaaacccgc catcaccact taaggtaaat acttgttttt ctgggtagct
     3061 tagttgtgcg gcaattcctc ctggcacacc attacccata gttgcgaacc atccagatgt
     3121 cgtatgtttt tgtttaccgt tcatattcaa taaacgaata gaatggatag tcgtgttacc
     3181 gacatctgtg acgaaaatcg catcgtcttc agcaatacga ttgatttctt tatagacagc
     3241 ctctggacga atcggttctt cctctcgatc ttcaaaagat ttcaaccaat ttacccattt
     3301 ttctttattt tcttgatttg ctaggtacca gctatcagca gggcgagcat cccctaactc
     3361 gacaagtctt tgcaaagctg tgtttgcatc accgaggatc gacaaagatg tttcatggcg
     3421 tcgtccaaat tttgacgcat cgatatcgat ttggataaat tcagcagttg gattaaaaaa
     3481 tgcacgtcca aatgggaagt cgctaccgac aaataagatc agatcggctt ctgccaatgc
     3541 ttcatttccg ggtttagtag cgacacgtcc agcaaaacca agaaagtttt cataatcatc
     3601 aggaataatt ccttttgcta gaacggaagc gacaacagga actgaaaaat gttctgagaa
     3661 ttctttgatt tgcggaaatc cgtttcgcgt tccttgacca acataaagaa ctggtttttt
     3721 tgctttttca agataaggca aagcagctag caaatctttt tcttctggta atatcacact
     3781 tgttttgtga gtgtgagcgg tggagaaagg ttgttcgtca atttcttcaa aaccaagatc
     3841 aacagggata gtcacgatag ccacgccttt atgctcatag gcggctttaa tggcttcatc
     3901 tactacatgc ggaagacttt gtggtgtcat gactgtacga ttgtatacgc taacatctgc
     3961 gaaaatagga ttttcattta gttcctggaa agagttatag ttcatggatg tagaagcaac
     4021 ttgtcctaag aacgctacta gaggcacatg gtccatctgt gcatcataca aaccattgat
     4081 caaatgtgtc gcaccaggtc ctgcagagcc gaagacagcg ccgactttcc ccgttaattt
     4141 tgcatctgca gcggctgcga gtgcgccgac ttcttcatga cgaacttgaa tgtagttgat
     4201 ttcggttttt tcttgatata gcgcatccat aattgaattg aaagatcctc cgggaatgcc
     4261 gtaaatatgg tcgatacccc agctttcaag aacttttacc attgcgattc ctgcattgat
     4321 ttttgacatg gtgtttcact cctttagcaa tgatgataca taaatttttt gtatctagag
     4381 tatagaactt tttatcgaaa atcccaacta attcgtcttt tcacaaaaat gtagtcatgt
     4441 ttttgggaat atgctagagt agtacataga tagattcaag agaggggaat ggcatggttg
     4501 aatggctatt gagacttgaa ccttggcagc aagcacttgc tgggacagct tttacttatt
     4561 ttatgacagc tcttggtgcc gggttggttt ttttctttaa agaaatcaaa aaagaagtgc
     4621 taaacttgat gttaggattt gcttctggtg tcatgattgc tgcaagtttt tggtctttgt
     4681 tagatccggc tattacaaaa gcagaagaaa atggagatat tgcttggcta gttgtaagta
     4741 ttgggtttgg tttaggcggt gtgtttttat atatggcaga taaaacactg ccccatatgc
     4801 attttggacc acaacatgaa gcagaaggat tgcctaccca tttaaaacgg acgatcttgc
     4861 ttgttttttc tattacattg cataacattc ctgaaggttt agccgtgggg gtagcattcg
     4921 gtgcagcagc aactgcggat aatccgacag ccgctatatt agccgctgtt tcggtggcgc
     4981 taggtattgg tatccaaaac ttcccagaag gagcagctgt atcaatcccg ttgcgacaag
     5041 aaggtctgag tcgtaaaaag gcctttgttt acggacaagc ttctggaatc gttgaaccaa
     5101 ttgctggagt gattggagcg ctactagtaa cgaaagtgga gctgctgctt ccttatgcac
     5161 ttgcttttgc cgcaggagca atgatttatg tcgtggtgga agaattgatc cctgaagcac
     5221 agcagacatt gtccagcaaa catcattttg cagtttttgg cgtcatgagt ggatttatca
     5281 ttatgatgat tttggatgtg gcattaggat aaataaaaaa aatatatatg atatatcaaa
     5341 tagggccgcg aacttatatc gcgaccctat ttttttagta agttatatca taatgaagtg
     5401 aatggtatca tacattaata atagtttttt ctatgtgtat ttcctttgat ccagcgaaca
     5461 agccagatga taagtgcgat tgggattaga actttgaccg caaaccataa aagcccgctt
     5521 aggacactga caaaaagact gatgacgaag ctagctgcaa ttagcactaa aagaaccatg
     5581 aagatattta agaacatatt tttttgacgc atacaaaacc ctcctcttgt tcattcttta
     5641 ctatagaaaa agtataacag ggattgttta aaaacacctc caactgaaga ctgattttta
     5701 cttcatctac ttaaatgatc aaacaattgc tttttctctg gtttatcatc taaaatagag
     5761 cggaaaagga ggagaatatc atgcctaaaa atcgtcttga agcatttaca gatgctgtaa
     5821 tcgcgattat catgactatt ttagttttag aacttcatga acctaacgga gacacgtggg
     5881 aggcgctcgc tgcattaggt taccgatttt ttatctatat tgtcagtttt atcattttag
     5941 cgatttattg gaacaatcat catcatttat ttcaagttgt acataagata aatggacggg
     6001 tcttatgggc gaacagtttc tttgtttttg cgctttcgct ttttccgttt gcaacttcat
     6061 ggatcagtga gtacatcaat agcctggctc cagaaatgac ttatggtttt gttaccttga
     6121 ccgctaatat tgcgtattat atcttggcaa aagaacttgt caaagcaaat aaaggccacg
     6181 agaaagcatt gaaggcgatg ttgaataatt acaagaaatc gtatctatcg attggtttga
     6241 atgtgttagg aattgtctta gggtatttag tagcgccagt agccgtgctg atcgcaaaca
     6301 tcgtgattct agctgcttgg atcatcccaa gtcgtaccat cgaatcacaa tatcggtaaa
     6361 atgatccgtg tttaaaattt aagagaaaaa tatagaaaaa ataaataaac gatcaaatat
     6421 ccgagtgata ctagtattca aagagggatg cagatggatc aaaaaagaat tcatgtagga
     6481 ctgattacta gttttgtcac gatgcttatt tatttggatc aaggtcattt gacttggaca
     6541 gtagttggtg tcgtaggatt tttgacatta ttcacagcaa taaaaaaata aacatcttta
     6601 tgtaatctga tgttctatct atttaagaaa agcatgttta cagcagtatg attctgttgt
     6661 aaacgtgttt ttatttgtgg aaaatttaat ttttagaaaa gtgtatcgaa aaatagatag
     6721 ttagtttttc cacagtggat aacttcgtaa gagataaaaa taaaaaatta gtcaaagaag
     6781 ggcgtataga tttcttttga taggagatat acaacagaaa tgaataaata ttaacgtgtt
     6841 ttcaaacagt ataaaacggt gtggtttttg gaataaaaaa ataacatatc tcattttaca
     6901 cttttgttat tttatactta aaaaataacg acacagaaaa taccgtgtct cagatttctc
     6961 tactacttct aaaaactact gtttttttcc tttgaaatgc cttcaaaaag taggatcagg
     7021 cagaatatac tggcagaatc aaggagaagg gagcctaaat aaggagaaaa accatagaaa
     7081 atataaagta attacttata aaacaagctt tttatagaaa aataatatac ctgagtaggg
     7141 tataaattaa gacggaattc ctttctagat tgagatattg actaggaaga atgttaagat
     7201 tttaagcctt taagctaaaa aaaaaccctt tttgttaaat aaggggaata tagcctgtca
     7261 gtttcaaact gcaagtcgtc ctgctgcaat aatatagtag attagagatg aaaatagatt
     7321 tttttaaacc aatgactgaa taaaaagacc gtcatagata cacattggaa tgtgtctatt
     7381 acggtctttt tttacgaacg attttattga agacggacag ttcgggtcaa aaataaaaaa
     7441 gctacgatca gaaataagaa taaaatgtat cccaaaataa tggctagacg gtctaactta
     7501 tttgtcgata gatgtttgtt tagaagttga taggcccata aacctatcag tcctcctgtt
     7561 gtattagtta tcaaatcagt gatgtccgct acgccaatac cgaataggaa ttgaatcaat
     7621 tctgccaaga agcttacaag gaaaataatc cctaattttt tagaaaaaga aagtctcttg
     7681 aaattgacat tcaaaagcac cccaaaagga aaaaagacaa tcaagttata agtggtctca
     7741 cgtaataccg tcgtattttc aaaagaaaaa gtagaaaaag ggacgagatt gacattgctg
     7801 taagaataag tgagaaattg tggaagatta aatgatagct tgaataaaat caaccataat
     7861 agaaagaata aataaatccc taataaaaat tttgatacat accgcataga catctcctcc
     7921 atttaaaaag tataccatcg aaaaccgctg aaaaatcata aaaaagtatg aagtttaagg
     7981 accaacgtag ttatcgtacg aaaattagaa gctttttttt gttgggaatc cggtttcttt
     8041 aacaaagcta agatagcgag ttgcttggaa aagttgctat cttttttctg tcaaaacgac
     8101 tcggaatgtt cgttttttgt tctaatttct ccaagttgtt tactttttga tactaagttt
     8161 atgaaaaatc aagaaatagt tgttatacta ggtaatgctg acaaacggga ttggcatttc
     8221 atcttggttc agcttttttt ccaattacta ggaaggaggg atagattgtt caagacttat
     8281 tttcgtttca ataaaataca agataatcct tttcgtatca tgaatctgat gctacttatc
     8341 tttattgtat tatggttagg ttacataaat catgattttt tgatttcaag tttttcatca
     8401 ttagggatct ttactttttt ctattatcaa aacataccga tgaaatattt gctgaaacgt
     8461 atgtttctga tcggttgcgg actgttggtt gctttcgttt tggggatctt atcgacttat
     8521 gttttatggc ttgaaccatt tgccgtagct ttggttgctt tttccagcag attcgtgttg
     8581 cgattattcc atatttctaa accaggtggc ttgttttttg cgatgctttc tgccatggga
     8641 acgagcatgc agctgccaat cgctcaatta ccgatcgtct cactttattt ttttatgggt
     8701 gtcgtttttg ccctgattgc ggcagtgatt acaaaattac tggattcacg gcctgagcag
     8761 acaattgaaa aagcaacttt aaaagaaaga tttcacgaag agcctttagt gatcattgat
     8821 tctgttttct acagcgctgc cttatttctt tccgtttatg tcagtcacgg cttgaatctg
     8881 cataatcctt attggttgac cttgtcatgt gcatcgattt tgctagcaga aaacttggat
     8941 gcgatgaagc atcgacaagt ccaatatctg attggatcga tgggtgggtt atgtgtgtcg
     9001 gcattcttgt catttgtgcc gtttacgcag ttgcagacca tttttctgat cacttttcta
     9061 tatggaatcg cacaatttct agttgctaga aattatgcag ttgctaatat ttttcttaat
     9121 ccgatggcgt tgatgctatc tacacttatt cgtggagcat acttgatttc tttgatcgaa
     9181 tatcgttttt tagggatcgt cataggaagt ttcatcggtt taggtgttgc gtgggtaatg
     9241 acggttggtt tgcaacatta tttaacggtt gttcgtcaaa aattagaata gaaggacaaa
     9301 tatatgtgcc aaaagaggtt atgacaagat ttttgtcaca acctctaatt caaggtgttc
     9361 aaaagccaga ttctcagcat taagtcaaat tcacacaaaa atgtggaaag gaactttcaa
     9421 aaaaatttta tatttattct atcaaaaaat tttgtttatg atggtaactg aataaacttt
     9481 cctgagatgg tcaatgcttt ccttgaaagt cttacagata ttctttcttc atagaaagtt
     9541 taagttttat agttagtgta caataaaagt atgtttatac catatggtgt ccggataatc
     9601 agtcatttaa acaatgaggt tcaaagatat gaaaagggga aatttgatga agaaaataag
     9661 caatgaaatc caaattctgg cagaaacttt aactcttccc aaagtcgtta tagagcaaat
     9721 gattgtacaa gcaaaaaaca tccttgatga ggtgtttgag caatatagtc atgaactaat
     9781 ggatcctaat aaagcaaagg cgactgcaaa gaaaatagac aaagtctatg aagaggaacc
     9841 ttttgcagca ttagctattt atctatatgc agcttctcaa agttggaaaa aaatttatca
     9901 accattgaag attccaagaa ctatctattt ggcaacaatg aatgctttta ctagatttat
     9961 tcatgaacat ttccaagtaa caggaagcta tcgctttgac cgtggttttt ggatttggca
    10021 ttacactagt ggcttgatct ttcggattgg tgaattggag tacgaaatga catattttcc
    10081 gaaagggtac acggatctaa gattagaagg aaagcagtgc ctttctcttc atattccttc
    10141 cgatgcagat ttatctcaga ataagataag agatagttac gaaagtgcca ttcgtttttt
    10201 tgaactttat tttcctgatt accattacca agtgatgtac acagatactt ggttactatc
    10261 acccaatctt actaaatggt tgaaaaaaga gtcaaaaatc tgtctttttg cagccgatta
    10321 tcgattatta tcagttgatg aacaggacga tagtggagtc ccttggatct ttggacgagt
    10381 agatgcccaa atacatgatt atccagaaag tacgagttta cagcgacaag caaaagagca
    10441 attgcttgca ggcgagcaca ttggctctgg cttaggtatt cttacttcat aagtttagta
    10501 cttcgaaata gtttaaaaga gcgtgagaca aaagtaaaga acacttttgt ctcacgctct
    10561 aaacacgtat aaacggcgga agcagaagca actccttcgg aaataagctg aaattcacaa
    10621 aaatttgaaa agcaattttc gtgaatttct tcttatttct tggagttaaa cgcttctgtc
    10681 ccagcctctt ttttagtgtt ctatcgaaca cacagtacgt tcaataggta aactagctat
    10741 aacaatagat attaaagtta acggacaaga gggccttttt taggtagcta aaacgtaata
    10801 atgaaaattt atttccagag ataggagtca atcagctagt ctgatcgact gttttaacaa
    10861 gttgactttc attttaactt ttgataccat ttaaaacaca aatcgtaatt gtttcgattt
    10921 gtgtttttta gcatgactac aatcaaagaa gaaagtgggt cgtccatatg gaaaaaacag
    10981 atatctcaag tgcataccgc cgcttgaaaa gcccaaatat caaaacacga aaacgtgcgc
    11041 tgaagatcat caaagatgtg aaacggaata gtgggaaaag gtaagaagaa ggaaacttaa
    11101 ttaaaaaaat agccgaaaaa cgtttttcgg ctattttcaa taatcggttt ttgtgtaagg
    11161 tttccgaaag aactgctgtt gattttccat ttttaacata tgataaattg gtagaatctt
    11221 tcttttcaaa ttgataccat tccctaattc cagttatata gttaactaca gaaccacaaa
    11281 gcacgtacgt ttataaaagt attatctgta gttatttttc aattcccttt caacctctta
    11341 ttttgaccag tagtattgat cactttacct tttaacacct ttgttcgttt ttgaaacatt
    11401 tttagtcaag aatggaaacg taactacata atcaaaggtt ttgcgaaata tttcatgaaa
    11461 tatttcatgt agaagcgagc aatacggttg caaataacca ttatcgttta ataagcagtt
    11521 acgaaagctc ccaatatctc taacgttcag ctcactccat ttcttttctt caaaaaaatc
    11581 agtgattcgt atctctttct atttgtcgaa aaagttaact ttaaaaagta acgccgaaaa
    11641 aatatgcaaa aaaataaaaa agcagttact attgctagaa taacatcaag gaataataag
    11701 ttttggtttt cagataatag tcgataagtt gtgtattgga attttagata cagtaataaa
    11761 gtatttttca tgaaattttg tgagaatcac tattacaagt atctttaata aaattaatgg
    11821 ttaaggagga acttaaagta gaatgtaaat gaatagttgt agtcagtcga ttgtgatact
    11881 agactcaaag ttgcaggaat aagtttttca atttgtgatt ggaagataaa aaatgaaaaa
    11941 gaagggcttt tttttatact ttgttgattg tagtgtttat tttccctctg tttagccaag
    12001 taacattttc tatgactcaa ccagtttcaa gtgaggaaca tgataacctt tttcgtgcta
    12061 cagaagagtt taagaaatat caggaaaata ttgttccgga gactccatta gctagtgagc
    12121 caattactga tattgatgga aaccaaatag gatggtatat acagtacgaa gttatggtgg
    12181 taaataatga ctcaatagta aaaaatacag taggcttaga gctaacaccg attgaaaagg
    12241 tgagttcatt gttaacgtat atttatactg atgaaagtga cgagactgag atcattttaa
    12301 cggattactc aaaaattgct actgataaaa agtatatatt gtggatgtag acactagtga
    12361 aatactttat gatatagaaa ttgatgaaaa tttactagat gtagcacaag aaatcgatca
    12421 tcaaaagcag gaagctattc gatatgctgg tagaaaaggg aaaagaaaat atttattacg
    12481 tgaatgtagc aaaagttaga gaagatgaaa atgagtggaa agaattcaag agtcgctact
    12541 caattaactc gactccgaca tttacagttt acagagaagg atcgatagaa aaaactgttt
    12601 tttggactaa agaaagtgga atgtctttag ctgaagtaga agagtttttg gattatgtta
    12661 gtatgcaaca gtaagggagt tcttattatg aaaaattttg acacatatta tgttattgtt
    12721 ttttcgatat ctttgctgtt aatattacta actttaatgc agtataaaga gtatccagag
    12781 tattttattt taacttttgt atatttagta agtagctaca cacttctata taaattcaga
    12841 agttcttcta gagtttctaa agtttgtttc ttaattagct tattgattct ataatatttt
    12901 tgatttatat aggaaattaa aaatattata gaatcaacac tcagagaacg ggttggtttt
    12961 taatagattt aataagtact gataatgaaa tttctcctgg ttgggaaaac gaagttggtt
    13021 accctgtaga agaatttttt caagattact ttgcggagta tgccgatagg ataatgagag
    13081 attacgtaac agataaaact caagaagtca tcaatcaatc ccagtcatta aatgaattat
    13141 ctgataaggc gaaagaagaa gcagttgcca ttatttcttc agggattagt gactatattg
    13201 atatgagtgg tgaaatcaat tatggcgata aagacaaaat tgtacgcatg ataaaagctt
    13261 ttatcaaaac ttttgatgtg aaggcagatc ttaagtttaa tgatacttac ctagtaggaa
    13321 aattaattaa tatccttggg acagagaaag atacggaaac gtttatttcc tctttgtcta
    13381 tgttgtttac agataagcat ttttcaactc agcttggtgg agaggaacta gtggaaatct
    13441 tttaaccatt acgcccagca ttaataaaag tatatcaaaa aagtactcct gatgattttt
    13501 aagattggtt tgagaaataa tgtgaaaaca ctatttttaa tgttaattat agatagagat
    13561 gaacgcgtca tatggttaaa agaatgaaaa agtcaaagat acactgctat atttcactaa
    13621 ggatatagca gtgtatcttt catgtcgttt cactggcagt tttttataaa aggaggtgtg
    13681 catttcagtt gcttttcttt ggtagttagt tgaatcgttt aagaattaac ggatgtggca
    13741 gacaggtgct ctgtccaaaa accagtaaaa tctttgatgg ttccatcttt atttagctgt
    13801 gcctgttcaa atactgtttt gtttttaccg aatggatcaa ttgcaataat tgttccgatc
    13861 cccgcacgtt tggcagcaag taatcctgag taagcatctt cgataacaag acaatcagcc
    13921 ggagctaagc tcagtttgtc tgccgcttta agaaaaatat ccggttgcgg tttcccaggg
    13981 aaagagccgt cgtcatagac aatcttgtcc cagtcaaacc agcgggctaa atcgaaaata
    14041 tcaaaataaa aagcaacatt ctctttgaca gtagccgtgg caatcgttaa tggaatctgt
    14101 tggtcagtca gctggtcaag agtcgcttca agcccttttg tcaactgaag ctcgttttca
    14161 ttttgcaagc aaagcatacg ataatagctt tctttttctt ctgacaatac ggcgatctca
    14221 gaggcggtca aatgctctga aatgaaatgt ttcaaaatct ccgtattcgt ccgaccatga
    14281 atatttttta aaatatcctc gtctgataaa ccatcttttg tatgatcatg tatcatatgc
    14341 agccaagcag cttcatgcag atgagagtcc aaaaacattg ttccgttgaa atcaaatata
    14401 atccctttca tagttacgct cctatagtgg tattttcggt tgaatcagca atttgcagat
    14461 cgacatattg tgcatagtgc tcttgaacct cccgcgagat ctggcgatcc gtaatgagca
    14521 gatcgaaatc atgcaaatta taaaacacat aaaaatcatc tcgattgaat tttttattat
    14581 caacgagtag atatttctta cgggaattat ttagagcgat ctgctgtgct tctccttctt
    14641 cggtactgta agtagagatc gcttcgttgt gaacgccatt tgaactgata aatgcttttg
    14701 taaactttag tcttcttaaa ttgtcgttgg tgatcggtcc gacaaatgcg ccggtatttt
    14761 tccggaaatc accgccaatc agtagaattt ctggtccatc tgcttgagca agaatatcaa
    14821 aaactggata attatttgta atgatccgaa ttttcttgtt cagtaaatgc gtcgccaata
    14881 gttcgattgt tgtacctggt cctaagaaaa tcgtttctcc ctcgtgaatc aaggaggctg
    14941 ctgtggcagc aatttctttt ttttcttgaa tctgcagagt ggctttttca gtgtgagaaa
    15001 gttcttgatc taaagtgtag gaaagacttt gagcccctcc atggacacgc agcagcttgc
    15061 ccgatttttc taattcatct aaatctctgc gaacggtcat atcagaaaca tctaattgat
    15121 tgatgatttc attaacggta aggattcctt ttttattgac catttctacg atagtaagca
    15181 atctttcttt tttcaacatt gtcttcacct ctaatttaag gataatctat catataaacg
    15241 gacaacagtc aatctaattc gaacaaaagt aaacatttag ggtggttttt atgtttgtta
    15301 caatagattt tattgctgtt ttctggtttt tatgattatt tgtgtttgtt tttgttgaca
    15361 aatgttttgg atgcgtttac aatgcaatca gttagaaaga gcgaaaactg attatagatt
    15421 tgaggagaga tgtacatgct taaattacca gaagatttta tttttggcgg agccacagca
    15481 gcctatcagg ttgaaggagc cactaaggaa ggtggcaaag gcgctgttgc ttgggatgac
    15541 tttttagagg aacaagggcg attcagtccc gatccggcaa gtgattttta tcatcaatat
    15601 gcaaaggaca ttgaattgtg tgaacgtttt ggtgtaaatg gtctaagatt atccattgct
    15661 tggagccgca tttttcctga tggagctggg aaaccaaatc cagaaggaat cgctttttat
    15721 catcgtgtgt tcgaagaatg taagaaaaga aacgtaacgc cgtttgtgac gttgcatcat
    15781 tttgataccc ctaaacgttt gtttgaccat ggagattttt tgaatcgaga aacaatagaa
    15841 gcatttgttt cctatgccat tttttgtttt catgaattca aagaagtcaa ggtgtggagt
    15901 acctttaatg aaatctatcc agttgcaacc aatcaatatt tgttaggtgt tttcccacca
    15961 ggaatcaaat atgattttac aaagatcgtc gcctgtcttc ataatatgat ggttgctcat
    16021 gcccgtgtag tgaactattt caaagaaaac gaacttccgg gtgaaattgg tgtagttcac
    16081 tcattagaga cgaaatatgc ggcaacagac gcgccggaag ataagcatgc tgccttttta
    16141 gacgatgcat tgtcgatccg tttcttatta gatgctacct atttaggcta ttattcaact
    16201 gaaaccttga ctgctcttga tgagatatgt gaagcaaatc aggccagcta tcattttcct
    16261 gaagaagatt tcgttgaatt gaaaaaagca tccacgcgta atgactactt agggatcaat
    16321 cactaccaat gccattttgt caaagcttac gatggagaaa atgcaatcca tcataacggt
    16381 acgggtgaaa aagggacctc tgtttataaa gtgaagggaa tcggagaacg tatttataaa
    16441 gaaggaattc ctcgaactga ttgggactgg ctgatttatc cagaaggtct atatgacttg
    16501 ttgctgcgaa ttaaaagcga ttacccacat tacaacaaaa tctatatcac tgagaacggg
    16561 atggggtata aagatcagtt tgaagatggc attattatgg atcagccgag aatcgactat
    16621 ttgagagtct atttggaatc cttaagcaag gcgataacag ccggggtaaa tgtgaagggg
    16681 tattttttgt ggtcgcttat ggatcttttc tcatggacaa atgggtataa caaaaggtat
    16741 ggcttgtttt atgttgattt tgaaacccag aagcgttacc caaaagaatc agcttactgg
    16801 tacaagttgg tcagtgaaac caaaacgatt atttaataag tgataatgga ggaagaaaag
    16861 atgaataaag aggaattaca aatgcttggt tttgagatcg ttgcatattc aggcgacgct
    16921 cgcagtacat tattgaaatt attgaaagaa gtaagacaag gaaactttga acatgttgat
    16981 tcggcgttga aagaagccga cgaaaattta acccttgcac ataattcgca aacaaaaatt
    17041 ttagcggaag aagcatctgg gaaagagatg gagatgggat tcatttttat ccatgggcag
    17101 gatcatttaa tgaccacttt attgctgaga gatctgattc aagactttat tgtactgtac
    17161 agacagaatc aaggatagga gaagaacgct atggatggaa tcattaaaca aatcgaaaaa
    17221 gggaaaccat tttttgaaaa aatctcacgt aatagttatt taggagccgt tcgtgacgga
    17281 tttttaacag cgatgccagc tattttattt tcaagcattt tcattttgat tgctgcggtt
    17341 cctgagattt ttggttacca atggcctgaa tctgtctcca catggctatg gaaagtctat
    17401 aattattcga tgggtgttgt agggttactc gtttcagcaa ccactgctcg ctgcttggct
    17461 gattcgatga atcgtcgctt accgaaaaac aaagtaatca acaccacctc tgtgatgctg
    17521 gcctctgtgg taagtttcct gttgttaagc gtctctccga ttgaaggtgg attttcaacg
    17581 gaatatatgg ggacaaaggg actactggct tcctttgtcg ctgcattttt aacagttaat
    17641 ttatataagt tttgtgtgct gaaagatatt accattaaaa tgcctaaaga agttcctgga
    17701 acgatttcgc aaaccttccg agatattttt cctttctctt tttcagtatt tgcggccgtt
    17761 ttaattgatt taggcattcg acaaatcttc caaatctcat ttgcagaagc aatcattacg
    17821 gtgctgcagc cgctatttac agcagctgac gggtacttag gaatcgctat tatctgggga
    17881 gcgatggcgc tgttttggtt tgtcggtgtt catggaccgt cgatcgtgga gccggcaatt
    17941 gcggcaatta tctatgccaa tgtggaaacc aatctgcaat tgttcaattc cggtgaacaa
    18001 gcttctaaag tactgacggt gggtttaggg aattttgtag gaactatggg aggaactggg
    18061 gcaacattgg ttgttccttt tatcttccta ctctttgcta agtctaagca gttgaaggca
    18121 gttgggaaag cttcctttat tccagtaagt ttcgctgtca acgaaccatt gctatttgcg
    18181 gcacccatga ttttgaaccc ttattttttt attccatttt tgttaacacc tgttgtaaac
    18241 gtttgcctgt tcaagttttt tgtcgatgta ttgggcatga acagctttat gtacgttttg
    18301 ccttgggcaa ctccagcacc gatcggtttg gttctaggaa cgggcatggg tatcttagct
    18361 tttgttctag cagcggttct aatcgtcgtt gacttcctga tctatctacc attttgcaaa
    18421 gcatacgatg ctgtcttagt agagaaagaa gcacaaaaag cagaggtgat cgcaaccgag
    18481 gaaggtgctt ctgccgatgt acgtgaggaa gtacctgtgg cagcgagtca agttatcagc
    18541 gatgcaaata aagaaatcaa tgtgttggta ctttgtgctg gcgcagggac aagtgcgatg
    18601 ttagctaatg ctttaaaaaa aggtgcatct gaatcgaaag caccgatcag tgcaatggcg
    18661 ggtgcttatg gttctcatta cgaaatgctg caggattttg atatggtggt cttagcaccg
    18721 caagtcaatt cttactatga tgatatcaaa gaagacaccg atcgcttagg aatcaagctg
    18781 gttgcgacaa aaggagcaga atatatcgga ttaacgagag atcctgaaaa agctgttcag
    18841 tttattctga accaatttca ataaaggagg agccataatg aaaatgggaa tttggttgcg
    18901 taaagctgtt ttatttgcag ctgtgttagg ggctttgggg gctgtttcaa aaactgttga
    18961 agcatctgcc agcgaattta ttcgcggagc agatatttcg atcctgtcag atatggaaaa
    19021 atctggtgca aaatattatg aagacgatat ttcaaaagat gccttagaga ttttaaaaaa
    19081 taatggtgtc aactatgttc gactgcgttt gtggcaggat ccttataata gtaatggaga
    19141 aagttatgga gcagggacaa atgatctgga aacgacgatt gaccttgcaa aacgagcaaa
    19201 aaatctggga cttaaggtgc tgctggattt tcactacagt gatttttggg ttgatcctgg
    19261 gaaacagaat cttcctaaag catggcaagg tctgaccttt gaagaaatga atacggcatt
    19321 gtacgactat acaaagaacg ttctgtcgga aatgaagcag ctggacgttt atcctgatat
    19381 ggttcagatc ggcaatgaac tgaatagcgg aatgctctgg ccttatggca agtcttgggg
    19441 agaaggcggg ggagaatttg atcgattggc tgcttttttg aagtctggta tccaagctgt
    19501 tcgagacact caacctaaaa caactccagt aatgctccac ttagctgatg gtggcgatac
    19561 aggagcattt acttggtggt ttgatgaaat cacgagtcga ggtgtgtcat ttgatttaat
    19621 tggagtgtcg tattatccgt attggcacgg ttcaatgaat gaacttcaaa ccaatatgaa
    19681 tgcgatcagc caacggtatg gtaaagaagt gatcgtagtt gaaacagctt atgggcatac
    19741 aacagcgaat gccgatacta tgccaaatgc ttttggtgaa gccgaagcag ctgcgggggg
    19801 atatgaacca acaccgacag gacaagcaga gtatttgctg gatcttgccg atcggattca
    19861 ggcagtaccg aataatcgcg gggcgggctt cttctattgg gaacctcttt ggtacaacgg
    19921 aaatgtgagt tgggcaacac aagcaggtat gaattatctc agtgttcaat ccactatggg
    19981 aaacgaatgg gacaaccaag cgatgtttga ttttgctgga aacgccttgc caagcttgcg
    20041 tgcgtttaaa caagcagggg cgcaaataaa tctagttaaa aatgcaagtt tcgaaagcga
    20101 tggaccaacg accagtcctt ccaattggca aacctggttt caacaaggaa ccgctaaggg
    20161 tacgatcaaa acggaagcgg gcactttttt tggggactac aaactaactt tttggcagga
    20221 tcaagcatac gaggcatcag cttatcaaaa tgttagtggc ataagcaaag gaacttacac
    20281 attgagtgcc tatgtaatgt ctgggggaga gtttgatact aatcagttat atatcaaaaa
    20341 ttatggtgga gcggaactaa atactgcggt tgttaaaaca agtgaatgga caaaaattac
    20401 aatcaaagac attccaatta caacaggtgt ttgtgaaatt ggggtttata gcaaggcttc
    20461 aggaaatgct tggacgaacg ttgattttgt ttcattggtg aaacaataga ctgcggatcg
    20521 tttcgattca agatcggagg ttcccttcag ccacatcgtt agcgtagaag gcaggaatcg
    20581 aacctgcacc tcgcctttgc caaaaataac cagaaacgat ttccagtcat ttttaccaaa
    20641 acgagtaaag caccagactt catctacact ttgtattatg ctaaagagag ttcaacgatt
    20701 tcgtaagaag caatgaaaaa attgcaaaaa gttgtgcaga taacataaag tttgtttaag
    20761 aaagggtaac cttagaattc cgtcgtgaat atgatttgag cacttagatg gatagaaaaa
    20821 agttctcgga aaacagttcg tttttcgaga acttcttttt atgataagaa tgaaacaaat
    20881 taacttatat tatagtctct tttggtaggg aaccatctta tttttaatga aaatcaagca
    20941 ttttagctat tgaagaatgt tgatttatag ggattccccc tccatattat gttggctctt
    21001 tattcccact ccactgttgc tggtggttta gaagtgatgt catacacgat acggttgacg
    21061 tgggctactt cgtttacgat acgtacagag attttttgca agacttccca tgggatacgg
    21121 gcaaagtcag cggtcattcc gtcgattgaa gttacagcac ggataccgac tgtgtagtcg
    21181 taagtacgtc cgtcacccat aacaccgaca gagcggatcc ctggaagaac agtgaaatat
    21241 tgccagatat cacggtcaag tccagcagct gcgatttctt cacgcaagat agcatcagat
    21301 tcgcgtacga tttctagctt gtcttcagtg atttcgccaa gaacacgaat accaagacca
    21361 ggaccaggga atggctgacg ccaaacgatt gaatcaggca tgcctaactg agtccctaat
    21421 tcacggactt cgtctttgaa taatgtgttt aatggttcga tcaattcaaa ttgcatatct
    21481 tctggcagtc cacctacatt atggtgagat ttgatcgtct gtgctgtttc tgtaccagat
    21541 tcgataacgt cagtatacaa cgttccttgt gctaggaaag agacgccttc ttcaccagca
    21601 agttttgttg cttcgtcatc aaaaacatat acgaattcat tcccaatgat tttacgtttt
    21661 tgttctgggt cagatacacc tttcaacttg tctaagaagc gatctcttgc attgactttg
    21721 atgatgttca agccgaattt tccgcctaga ctttccatta cttgttccgc ttcgcctttg
    21781 cgtagcagac cgtggtcaac aaagatagat gtcaattggt caccgatcgc tttttgtaaa
    21841 agaaccccaa cgacactaga atcaacgcca cctgaaagac caagcaagac ttttttgtca
    21901 ccaacttgtt cacggatttt ttctacttgc atatcgataa agttatccat tgtccagtta
    21961 ccttcacagt gacaaacatc aaaggcaaag tggcgcagca attcgattcc gtattcggaa
    22021 tgacgtactt ctgcatggaa ttggatacca taaaaattac gtgttgtgtc ttggatagaa
    22081 gcaatcggac aatctttgct tgttccgact gtttcaaagc cttcaggaac tttagttacc
    22141 aagtcaccat ggctcatcca tactgtttgt tgttttggtg tttctttaaa caagacagct
    22201 tgatcgcttg ttacttctaa caaggctttc ccatattcgc ggtttttagc aggctctacg
    22261 gaaccgccaa gtttgtacgt gatcaattgc ataccatagc aaatccctaa tacaggaata
    22321 cctaaattga agatctcagg atcgatccca aatgcattct catcatatac actgtttggt
    22381 ccgccagaaa gaatgattcc ctttggattc atcgctttta cttcttctgc agtaatgcgg
    22441 tggctcaata attcggaaaa gactccaaga tcacgaatac gtcttgtgat caattggtta
    22501 tactgactac cgtagtctaa tacgataatc ttttcaacgt tcgtcatatc ggcaacgttt
    22561 gtcaaattta ttacccctat ccctttaaat tttatctcaa aatagtcaaa ctattttaaa
    22621 atgctaatat tttcgcatga aaatcgaatc gatgatatga ttttcagttt tatggagaat
    22681 tatatcggct cttcctcgtg taggcaagat atattcctgt aaatttttca aattcacatt
    22741 tttccataca tcttttgcca ttttaaaggc ttcttcacga tctccgatag caaaacgata
    22801 ataataattc tctggatttt ggaaagccgt atccagtaac gcaccaaaac gatccaaata
    22861 ccatttttcg atcagcacgg gatcggcatc gacatagaca gaaaaatcaa aaaagtcgct
    22921 gacgtagatt tgctgattcg caggtaattg aagcgtattg atcccctcaa cgatcaagat
    22981 atcaggctgc tggatcaatt cgtacttgtc tggaatgata tcatacacat catgtgagta
    23041 aacaggtact tttatctctt cctgaccaga ttttacacgg ttcaagaaat cgatcagcat
    23101 ctccatatca taactttcag gaaatccttt acggtccatg attccacgct cttttaatat
    23161 acgatttgga taaagaaatc cgtcagtcgt gatcagctga acgtttcttc gtttgaaggt
    23221 acgagacaaa atcgtctgca gcagtctggc tgttgtactt tttccaacgg ctacacttcc
    23281 ggcgatcccg ataataaaag gcggtacttc tacgtattta tgaagaaata aacctttact
    23341 caagaacaaa gattcaaatt ctttcatata aagataaatc agatgagcaa gaggtacata
    23401 gatatctcga acatcctgca tggaaatgcg gtcattcaaa cttttgatat tatctagttc
    23461 atcttgtgtc aaaggtgctt gcccattacg ataaaattct cgccattctt ctcttgccac
    23521 acggtagtag ttcattggat cattcatatt agcctcctgc gttctcccat caatggaact
    23581 attttaacac aaaataaacg caaaccccac cacttaagag agattgccga tctttttgta
    23641 taatctttat aatagaaaga aacggagtct tattcttgac ttgcgcacgg atacataaaa
    23701 ggatagactg ttgtcatgaa agaaatgaga aggatggaag acatgacaaa tcattactat
    23761 tctgaacgcc cagatacggc gcacgatttt gaacaatggg cttttgagtt aaaaggcaga
    23821 acctttcaat ttgtaacaga ttctggtgta ttttcacgtg aaacagtgga ttatggttca
    23881 cgtgtcctga ttgatgcttt cgattgggaa gagttacctg atgaaggaaa gatcttagat
    23941 gtgggatgcg ggtatggacc gattgggtta gctttggcat ttgcgacaca gcggtttgtt
    24001 gaaatggtcg acattaatga acgagcggta agtctagcgc aaggaaacgc aaagcgtaac
    24061 caaatcgaac atgttgatat ccatcaatcg aatatctatg aagcagttca tgaagaaacc
    24121 tatgcagcta tcgtaagcaa tccgccgatc cgtgctggaa aaaaagttgt acatgaaatt
    24181 ttgacaggcg catatcctcg gttgaagaag ggcggtacac tgacaattgt gatccagaag
    24241 aaacaaggag cgccgagtgc gcaaaagaaa atggaagaaa catttggtaa tgcagaaatc
    24301 gtcacaaaag ataaaggata ttatatcatc aaaagtgtga aagaataact agctgaaaaa
    24361 tagtggagcg acgaaagagt ggaactgggc gtgcatgtac gggtacgtat cagttctttt
    24421 tttgttgaga agtttttaaa aacaaagaac tattttttct tcaaaaagaa atagtaggaa
    24481 cagagtcgtt gttttttacg ataaaataaa taagatacag aacttgtata gaaggctgcc
    24541 aagtcggtag ataaaggagg tttttatcaa aaaacatact ttcctttttt ctctattctt
    24601 ttcttggggg ttttggtaca ctgataggga atttagatag aagggagcca ataggatgaa
    24661 gctgaccatc agagatatcg cagaaatggc aggcgtatca gtaacaactg tctcacagat
    24721 tttgaataac aaaggaagca gatttagtga taagacaaga aaaaaagtgt tgtcgatcgt
    24781 gaatgaacat cattataagc ccgattattt cgcttcaaat gtgatcaatc gacattcaaa
    24841 gaccatcgga atgatcgtcc ctgatgtcac tgatttcttc ttctccaaac tgatcgaagg
    24901 tgtagagagc tatttgaatc ctttgggcta tgtgatcatg ttatgcaatt ctcgtcatag
    24961 ccaagaaaat gagatcaagt atttacaaga gctttcccac cgctcagtgg acggaatctt
    25021 gctggccaca ccaaatattt tacctgagaa atatgcatta gacagcggtt tttatcaaaa
    25081 aatgccaatc attttaatcg atcgcggatt gaatcgtcgg gataacggac ggcttatcgt
    25141 aaaggaatat gagggcgcct atcaagctgt ttcgctgttt attgaaaatg gccatacgaa
    25201 gatcggcatg ctgaaggaaa ccactggata ctatcaatta gaagaacgtt tcaacggata
    25261 tcgtcatgcg ctgaaagatc atggcctgcc ttttaatggg aaatttgttg aacatggaga
    25321 gttgactgtc caaggtggat atactgcatc aaaaaaatta ctcaaacata aagatatcac
    25381 ggctattttt tgcgggaatg atgccatggc gatcggatgc tatcaggcga tcgatgaatt
    25441 gggcaaaaaa atcccagaag atatctcagt cataggattc gatggattaa agctgtcaga
    25501 atacatgatt ccgcaattga cgacagtgca gcagccaagt tttgatattg gattttatgc
    25561 tgcacgtttc ctgatcgata cgatcgaatt tcctcaaaga aaagttccga acaaagtgtt
    25621 cgaaacaaaa ttaattattc gtgagagcgt aaaagtattg acaaagggct aactcggcgg
    25681 tatattgctt atgtaagcat ttacaaaggc tagttagtgc tttttttatt tttagtaaac
    25741 cagtttacta aagtggttta cctttcctaa aaataatgta taataccgaa tgaagacaag
    25801 gaggatcagg caatgcgaat ggtggatctg attgaaaaaa agagggatgg aaacgagctg
    25861 tcgaaagagg aaatcgagta catcgtcacg aactatacga atggaaagat tccagattat
    25921 caagtcagtg cattattgat ggcaattttt tatcaagaca tgacaaatga agaaatcacg
    25981 aacttaacat tggcgattgc taattctggt gatgtcatcg atttgagttc tcttgaagga
    26041 ataaaggtag ataagcattc gacaggtggc gttggtgaca cgaccacatt gattttagcc
    26101 cccctagtag ctagtgtcgg agtgacagtg gctaaaatgt ctggacgcgg tctaggttac
    26161 acaggtggta cactagacaa gctagaagca attcccggat ttcagatcga gctttcggat
    26221 gaagaatttg tacgcattgt taatgaaagt aaagtagcgg taattggtca atcaggaaac
    26281 ttggcaccgg cggacaaaaa attgtatgcc ttgcgtgacg tcacagcgac cgttgattct
    26341 cttccgctga ttgccagttc gattatgagt aaaaaaatcg cggcaggagc agatgcaatc
    26401 gttttggatg tgaccactgg agacggtgct ttcatgaaga acatcgaaga tgcaagacgt
    26461 ctggcaaaga ccatgacgag cattgggaaa ctggctaacc gagaaacagt ggcggttatc
    26521 tcagatatgt cagaacctct tggcgaagct atcggaaata gtctagaagt tgtcgaggca
    26581 atcgaaacat tacaaggaaa tggtccagaa gatctagtag aaatgtgcta cgccttagga
    26641 agccaaatgg ttgttcttgc tggcaaagct aagacaaccg atgaagcaag aacgttgctt
    26701 caagaagctc tggaatcagg taaagcgtta gcaaaattca aagaaatgat ccaaaatcaa
    26761 gggggagacc cagcgatcgt ggaacatcca gaacgaattt tgactgcacg ctacacaatg
    26821 gagcttcctg ctaaacaaag cggagttgtg tcaaaaatcg tggcaaatga attaggaatt
    26881 gctgcaatga tgctaggtgc tgggcgtaaa accaaagaag aagatattga tcacgctgtt
    26941 ggattgaaac tgcataaaaa aattggtgac actgtgacaa aaggtgagtc actattgacg
    27001 atctatagta acgacgaaga aatcacttct gtcattgaat tattatataa aaatattgaa
    27061 attggtgaat cggcaatgaa gccaacgttg attcatgaca tcatcacaga ataaaggaaa
    27121 aaagcggact ttaccgtttt aaagaaaagg ggaaaagaaa tggaactaaa ccgaatgatc
    27181 gaccatacta ttttgaaagc agacgcatct aaagaagctg tgatgcaaat tatcgaagaa
    27241 gcaaaaaaat accattttta ttctgtctgc atcaatccag catgggttgc gctagcgaaa
    27301 gaacaattac aaggtgagcc agtagccgta tgtacagtaa tcgggtttcc tctaggagca
    27361 aacacacccg agacaaaagc atttgaaaca acagatgcca tcaataacgg tgcagatgaa
    27421 gtcgatatgg tcatcaatat cggtgctttg aaatcaaagg atgatcaaca agtccaaaaa
    27481 gatatcgaag cagttgttga agcagcaaaa gatcgtgcgc ttgtcaaagt tattattgaa
    27541 acatcgttat tagatagaga agaaatcatc cgagcttgcg aaatagcaaa agctgcaggc
    27601 gctgattttg tcaaaacatc aactggtttc tcaacaggcg gagcaaaggt agaggatgtc
    27661 cgtttgatgc gtgaaactgt aggaccagaa atgggtgtca aagcttccgg cggtatccat
    27721 aacgaagaag aagcaatggc aatgatcgaa gctggtgcta caagaatcgg aacaagcgca
    27781 ggagtagcaa tcgtatctgg ttcaactggt gaaggctatt aattttttca aaggagaagc
    27841 tcatggcaga actcaaacaa gaatggatca acacagctat tgaagcgtta gataaagcct
    27901 atgttcctta ttcccatttt ccggtaggcg cttgtctcgt aacggaatca ggcaagattt
    27961 atcaaggcat caacattgag aatgcatcat ttggattaac gaattgtgcc gagcgcacag
    28021 cttttttcaa agcagtatct gaaggagaaa aaacatttac gcatctagtc gtagcggggc
    28081 acacccccga tcctatctct ccttgtggtg catgtcgaca agtaatggca gaattctgtt
    28141 cccctgatat gccggttacg ctagtaggag acaatggtgt gacgaaggca acgaccgttc
    28201 gtgcactgct gccttatgca tttactgaaa aagatctata actcatgttc attcagtcag
    28261 ctgactgttg aaaaataaaa caattatttt aggaggcttt acagaaatga aaaaagcaaa
    28321 attatttggt ttaggtgctg tcgcactagc agcagggtta tttttaggtg catgcggcaa
    28381 caacggctct actgattcat ccggtggcaa aagctcatca gacacaacaa ctgcagcatt
    28441 gatcacagac acaggtggtg tagacgaccg ttcattcaac cagtcagctt gggaaggact
    28501 agaaaaatgg gggaaagatc aaggactttc acgaggaaat gatggcttcc aatatttcca
    28561 atcttcaaat gaatcagatt acatcccaaa tattgaccaa gcattgaatg ctggattcaa
    28621 aacgattttt ggtattggtt ataaactaaa accagcgatc caagaacaag caacaaacaa
    28681 tacaggtacg aactttgtta ttatcgatga tgtcatcgat ggattagata acgttgtatc
    28741 tgcaactttc aaagacaacg aagcttctta tcttgcaggt gttgcagcag cttatacgac
    28801 tgaaacaaac gtagtcggct ttatcggcgg tgtaaaaggt gaagtaatcg atcgttttga
    28861 tgctggattc aaagccggtg ttgatgcagg tgcgaaagaa ttaggaaaag aaatcaaagt
    28921 attgaatcaa tatgctggtg acttctctgc tccagataaa ggacgttcaa ttgctcaagg
    28981 tatgtatgca caaaacgcag atatcatctt ccatgcttca ggcggtacag gtaacggtgt
    29041 attccaagaa gcaaaatcat tgaacgaatc aggcgacaaa aaagtttggg ttatcggtgt
    29101 tgaccgcgac caatcagacg aaggcgaata cacattaaac ggcgaaaaga aaaacttcac
    29161 attgacatct acactgaaag cagttggaac agtagtagaa gatttggcac aaaaatcagc
    29221 ggacggtaaa ttccctggcg gcgaacacac tgtttatgga ttgaaagaag acggtgttgg
    29281 tctaacagaa ggacaacttt ctgacgaagc gaaaaaagca gttgatgaag caaaagaaaa
    29341 aatcatttca ggtgacgtaa aagttccaga aactcctgaa gaaaactaaa accatttcta
    29401 tagccttgtt agacacatgt ttgacaaggc tatggtttga ttagaacaag aattgttcat
    29461 ttatccaagc tgccttgtga cagtttggat aagggaacaa ctccctgaag taatgtttgt
    29521 ttcaaaagaa gaacgctcac taagcgtgaa tcttagtcaa tcgttgccct agatagaaat
    29581 cgttaggatg tgaaaaaaag gtggttcaag aaaatattgt catagaaatg cagaatatta
    29641 ccaaagaatt tggaacattc aaggcaaatg acaacatcaa tttacaagta aaggcaggag
    29701 aaattcatgc gttgcttgga gaaaacggtg ctggcaaatc tacattgatg aacgtgcttt
    29761 ccggattatt agagccgaca tcagggaaaa ttttgatgcg tgggaaagaa gtaaagatca
    29821 caagtccgac caaagccaac caattaggga ttgggatggt ccatcagcac tttatgcttg
    29881 ttgatgcctt tactgtaaca gaaaacatcg tgttgggaag cgagcctagt cgcgcaggga
    29941 tgcttgacca taaaaaagca cgaaaagaga tccaaaaagt ttctgaacag tatggattgt
    30001 cagtcaaccc agatgcttac gttcgtgata tttcagttgg aatggaacaa cgggtagaaa
    30061 ttttaaaaac actttaccga ggagcagatg tactgatttt tgatgagccg acagctgtat
    30121 tgacccctca agaaattgat gaattaatcg tgatcatgaa ggaattagtc aaagaaggca
    30181 agtcgatcat tttgattacg cataagttag atgaaatcaa agcagtagct gaccgctgta
    30241 cagttatccg ccgtggaaaa ggaatcggta cagtcaacgt taaagacgta acctcacaac
    30301 aattagccga tatgatggtt ggaagaacgg tttcattcaa aacgatgaaa aaagaagcga
    30361 agcctcaaga agtcgttttg tctattgaaa atctagtggt gaaagaaaat cgtggattag
    30421 aagccgtgaa aaacttgaac ttagaggttc gtgctggcga agtacttggt atcgctggaa
    30481 tcgatggaaa cgggcagtcg gagttgatcc aagctttgac tggtttgcga aaggcagaaa
    30541 gcggacatat caagctaaaa ggggaagaca tcactaataa aaaaccccga aaaatcactg
    30601 aacatggtgt aggacacgtg ccagaagacc gtcataaata cgggttagtc ctagatatga
    30661 cattatctga aaatatcgca ctacaaacct atcatcaaaa accttacagt aaaaacggca
    30721 tgctgaatta ttcagtaatg aatgaacatg ccagagaatt gatcgaagaa tatgatgttc
    30781 gaacaacgaa tgaacttgtt cccgcaaaag ctttatcagg cggaaatcag caaaaagcaa
    30841 ttatcgctcg tgaagtcgac cgagatcctg atctgttgat tgttgcaaat ccaactcgtg
    30901 gactggatgt aggtgcgatc gaatttattc ataaacgtct gatcgaacaa agggacaaat
    30961 acaaagcagt gttactgatc agtttcgaat tagaagaaat tttaaatgtt tcggatcgta
    31021 ttgctgttat ccatgaagga gaaattgtcg gtatcgttga tccgaaagaa acatctgaaa
    31081 atgaattagg tctattgatg gcgggctata ccttagaaga agcacgaaaa gagttagaaa
    31141 agggggctgg cgcacatgaa tgatcgcagc gaaaaattcc gtaatttatt agtgcctgta
    31201 ctttcagttg ttttaggatt gatcttaggc gcgatattga tggctgcttt tggttttcag
    31261 cccatccaag gttattcttc tatgctagat gcagcccttg gttcgcaaag agggataggt
    31321 gaaacgttaa ggcaagcaac gccgttgatt tttacagcat taggtttttc tgtagctaac
    31381 tcagctgggt ttttcaatat tgggctttct ggacaagcac tttgcgggtg gatcgtcagt
    31441 gtctgggtgg cacttgcgtt tccagatctg ccaaaagttg ttttgcttcc gttatgcgtg
    31501 atcttaggtg ccttagctgg tgcgatggca gcggctgttc caggtttact tcgagcattt
    31561 tttggaacaa gtgaagtgat cgtaacaatc atgatgaact atatcttatt atacgtaagc
    31621 acatttgctt tacatgaagt gatgcctgaa agctatcgct caagtttgga ctcttccaat
    31681 atgatcagtc aaaatgcctc actgcggtta ccatggttaa cacaagcttt tggcggctct
    31741 cgcgtaaact caggattatt tttagcaatc atcgcgctta ttttcgtttg gctgctgatg
    31801 aagaaaacga ctttaggatt tgaaatccgt tctgttggat tgaatccttt tgcttctgag
    31861 tatgcaggaa tgagtagtaa acgtacgatc gttttgtcga tggtcatttc tggcgctttg
    31921 gcagggcttg gcggtgtggt tgaaggatta ggaacgtatc aaaacttctt tgttcaaacg
    31981 acttcgctat ctattggatt tgacggaatg gctgtttcct tgcttggttc tggatcagca
    32041 atcggtattc ttttatcagc gatcttgttc agtattttga agatcggtgg acttggcatg
    32101 cagacaggag caggtgttcc gtttgagatc gtcaatgtat cgattgcttt gattatcttc
    32161 tttgtcggga tcaacttcct gattcgtttc gtcatggcta aagtcttcca agggaaaaaa
    32221 caagaagaga tcgttgcgac aatagaatcg aaaccaacga atcaaaacca tgaagggggc
    32281 gaactataat gtcgactatc gaattaattg ccttgatcct tacttctaca ctggtttatt
    32341 caacaccgct aattctaacg tcactaggcg gaactttttc tgaacgaagc gggatcgtaa
    32401 acgtagggct agagggaatc atggtcatgg gtgcttttag ttccatcgtt ttcaacttga
    32461 cgatgagtcc atcacttggt tctatgacac catggatcgc tattttagtg ggtggcgtcg
    32521 taggtatcct attttctctg attcacgcag tagcaacagt cagtttgcgt gctgaccata
    32581 ttatcagcgg gacagtaatt aatctgatgg cacctgcttt aggtgttttc ttgatcaaag
    32641 catggtatgg taaaggtcaa actgataaca tcacgcagaa tctggggtat ttttctttcc
    32701 caggattagc agatattccg gtcattggac caattttctt taaaaataca ttcttacctg
    32761 cttattgtgc tattttgatt gctgtcctag cttgggtgat catcttcaag acgaaattcg
    32821 gcttgcgcct ccgttcagtt ggtgaaaatc ctcaagctgc cgacacatta ggtatcaatg
    32881 tatatgctat gcgttattca ggcgtactga tttctggctt gttaggcggt atgggcggtg
    32941 ctgtttttgc tcagtcgatt tccggtaact tttcagctgg tacgatcgtt ggacaagggt
    33001 tcatctccat ggctgctatg atctttggta agtggaatcc tttaggggca atgggtgcct
    33061 cattgttctt tggttttgct caaagcttga gtatcattgg cgcacaatta ccagttattt
    33121 cttcgattcc gccagtattg ctgcaaattg ctccatattt gctgacaatc attgtgctgg
    33181 ttgttttctt agggaaagct tctggtccaa aagcaaacgg gaagaactat atcaaatcaa
    33241 aataatcttt tagcgaataa aaagggtggg ttacgggaag tgtttttcgt ctcgcccttt
    33301 ttgttttaaa ggcaataaaa ataaaaagaa agaaggaata atcatgttta aacgcgtaca
    33361 tctgatcgtc atggattcag taggaattgg agaagcacca gatgccgata agttcggtga
    33421 tgttggttct gatacattag gacacattgc gaaagaagca ggattgaacg ttccacattt
    33481 agagcagctt ggtttaggaa cgatccgtcc tcttgaaggt gtggaatcag tgaaagatca
    33541 tcaaggctat gcgacgaaat tagaagaagt ttctgtaggg aaagatacga tgacaggcca
    33601 ctgggaaatc atgggattga atatcaaaac tccatttcgt gtgtttccta atggattccc
    33661 tgatgatctg atcaaacaaa tcgaagaatt ttctggccgt aaagtcgtat gtaacaaacc
    33721 ttatagcgga acagctgtta ttgacgatta cggtgaacac caaatgaaaa caggcgattt
    33781 aattgtatat acttctgccg atcctgtcct tcagatcgcg gcacatgaag aaatcattcc
    33841 tttagaagaa ttatatcgga tttgccaatt cgttcgtgat ataacaaaag atgatccgta
    33901 tatgattggc cgaatcattg cacgtccgta cgtgggtgaa ccaggagact tcacacgaac
    33961 aagcaatcgc catgattatg cgttgaatcc attcggacac acagtccttg attctttgaa
    34021 agaagcagga aaggacgtga ttgctgttgg aaagatcaac gatattttca acggacaagg
    34081 aatcactgaa tctgtccgca cgaaaagcaa tatggatggc gttgaccagc tgctgaaagt
    34141 tatgaaaaac gatttttcag gaatcagctt taccaattta gtagattttg atgcattata
    34201 cggtcatcgt cgggatgtag tcggctatgc gcatgcgatt gaagaatttg acttacgaat
    34261 tccagaattg cttgaagcga tggaagaaga cgacttgcta atgattacag ccgatcacgg
    34321 aaacgatccg acgtttactg gtaccgatca tacgcgagaa tatgtaccgt tattggttta
    34381 cagtaaaaaa atgaaagaac aaggggcatt gcctcaagga tattattcag atatttcagc
    34441 aacgattgct gagaacttta gtgtttcttc gactgaaaat ggcgaaagct tcttgaaatt
    34501 attaaaataa tctttttaaa taggagaaag caaatgacca agttaagcga gatgttacaa
    34561 gaaacgaccc agtttatcct tgataaagga gtaaaagaaa ttgattttgg tttgattcta
    34621 ggttcaggat taggtgaatt agcagatgaa atcgaagatg ctgtaatgat ttcttatgat
    34681 gagatcccgt tctttcctgt ttcgacagta gttgggcatg caggaaagct agtttatggg
    34741 tctctggcag gcaagaaagt gttagccatg caagggagat tccactacta tgaaggtcat
    34801 tccatgcaaa cagtgaccta tccagtacgt gtgatggccg gactaggggc ccattcagtc
    34861 attgtgacta atgcatgtgg tggtgtcaac gaatcatttg taccaggaga tttgatgctg
    34921 attaccgatc atatcaattt tactggtgaa aatcctttga tcggtccgaa tgaagatgca
    34981 atgggcccta gatttccaga tatgagtcaa gcttatacgc ctgactatca agcaacagca
    35041 aaagcagcag cagaaaaact aggtttggat cttaaagaag gcgtatatat gggctattct
    35101 ggaccaactt atgaaacgcc tgcggagatc cgaatgtctc ggacaatagg agccgatgca
    35161 gtagggatgt cgactgttcc agaagtcatc gtagcagctc acagcggatt aaaagtgtta
    35221 ggaatctctt gtattaccaa cttagcagca ggtatgcaag cgaatctgag ccatgaagaa
    35281 gttgtagaaa caactcagag agtcaaacaa tcttttaaag cattggttaa agaaacattg
    35341 acattattgt aataggagga acaataaaat gagtgtgcat attgaagcga aagaaggcga
    35401 gatcgccgat aagattttac ttccgggaga tcctttgcga gctaaatata ttgcggagac
    35461 ttttttggaa gatccagttt gttacaatca ggtacgcggt atgttaggct ttaccggcaa
    35521 atataaagga gaacgtattt ctgttcaagg aacaggaatg ggaatgccat cagccaccat
    35581 ctatgcccat gaattgatcc agtcgtatgg tgtaaagaaa ttgattcgag taggtacatg
    35641 cggtgcattg tcaaaagacg tccatgttcg tgatttagta ctagcacaag gtgcagcgac
    35701 cagttcttcg atgatcgaaa aaaatttcca agcctttcat tttcctccaa tcagtgattt
    35761 caatctatta ctgaaagcat atgagatagc taaagaaaag ggctatacgg ttcatgtagg
    35821 aaatgttctt tcggaagatt ctttctacaa agatgatttg acagagacgt tccaattagc
    35881 tgaacttggc gttttaggag tggaaatgga agcagcggct ctttattact taggcgcgaa
    35941 ataccatgtg cagacattaa gtttgatgac cgttagcgac catttgatca ccggtgaaga
    36001 aacaacagct gcagaacgtc aatctacgtt caatgaaatg atcgaagtag gattggaaac
    36061 agcgatagca gaataagaag gaaatgaaaa agctgccctg cattaagtaa taagaacatc
    36121 caagcaaaaa tagctcctca tgtttttgac ttggctggac ttattattgc aaatgtaagc
    36181 ttttgaacac cgtttaccaa gaggttgtga atctgccgtt taactctgag tcacaaggaa
    36241 caatttcaaa aaacagcttt tcatgtttga tgaatattgt gacttgtgac cgagaagttg
    36301 gcaggagaaa accgtttata cgaaaaaagg gactgtgaca aatcgtgtca cagtcccttt
    36361 tttatagtgt tttttatagg tagtattttt tagcaactgt taagtcatca tttaattcat
    36421 aaacaagtgg ttgacctgtt ggaatttcaa gatccatgat gtcttcgtca gagatacctt
    36481 cgatatgttt agctagggcg cgtaatgagt taccatgtgc agctactaaa acagttttgt
    36541 tgtctagtaa tgctggagca atttcatctt gccagaatgg caaagcgcgt tctaatgtca
    36601 ctttcaagtt ttctccacca ggaatatcgc gtttgtctaa cattgcgtaa cgacggtcat
    36661 ttgctgcaga accttcgtca gtttcttcca ttaatggagg aagagtatcg taagaacgac
    36721 gccagatgtg cacttgttcg tcgccgtatt tttcagctgt ttcttttttg ttcaaacctt
    36781 gtaatttacc atagtgacgt tcgtttaagc gccatgattt gatttgtggt acccaaagtt
    36841 gatctgaata ttctaagatc aagttacatg ttttgattgc acgagttaaa acagaagtgt
    36901 aagcaacatc aaattcgatt ccagcttctt tgattttgcg tccgccttct tttgcttctt
    36961 cgattccttc tggtgctaga tttacatcag cccaaccagt aaattggttc aatgcattcc
    37021 attcactaag accgtgacga gaaaaaacta attttggcat gtttagctct ccttttaaga
    37081 taggtttata tttctgaaat tttcagttct gttttattgt acaatttttt ggaagagatt
    37141 tccatcgaaa aattagataa gattctatga gaaaacaagt agagaatata aaaaaacgaa
    37201 cagtgcccac gcaactgttc gtttttaggt attagatgca taattgctcg atttcttttt
    37261 caggtaaatt gatatattta taacatgttc caactgaaac accgcatttt gaagaaataa
    37321 attggatcgt ttcttttttt tcataataga gacgtcggat ttttttgatc gtttttgcat
    37381 cgatttttgg tcttccgccg atttttcctt ttttacgagc ttcatctaat ccaactaatg
    37441 tacgttcttt gatcaatgcg cactccatgt ttgctaggtt ttccattaat tggaaataga
    37501 tttttcccat ttcgcgcgta tcgattcctt catcaagact aatcaagtgc agcccgcgat
    37561 ctttgaataa ttgcgtgagt tctgttaatt gccgcgtaga tttgcctaat cgatgaagtt
    37621 ggcaaatgac tagtgcatcg ccttgttgca tgtcagcgat cactgactcc aaatgaacag
    37681 cagtagaatc attttgttcc acttcatatg tctcatggaa aatttcttga caaccaaagt
    37741 cagataattg atcaacctga gttgttaaat caacgtcatt tatggttgtg cgtgcataac
    37801 caataatttt catggtgatt cctttctagc agtgattttc taactggata taacagtaaa
    37861 aatgtagcat aaagtacgtc aaaaagatag ttttttcgca aattttccgc tgtctttttt
    37921 tattggatga tcaagcagtt tttctttatt tacgacggat tgcgtcaaga atctcaacgc
    37981 ctttttctga gccgacaact actttagaaa ccatgtttag gaaaagccca tgttctacta
    38041 ccccaacaag ttcatctaaa taggtagcta agctttctgg ctgttcgatg acttctagat
    38101 gcagatcaat gatgtaatga ccaccatctg tggttaagac ttctccgttt tcgtctgtac
    38161 gcaagacggg ttggaatctt ttttcttcaa aaatatgaag tagctgttgg gagccataag
    38221 ggatcacttc aactgggagt gggaacttcc caagtttatc gactaattta gaagaatcaa
    38281 cgatccaaat cgtttctttt gagtacgtag cgactatttt ctcgaaaagc aaagcagcgc
    38341 cgccgccttt gatcccttga aaatcagcac tgatttcatc agcaccgtct attgtcaaat
    38401 cgactacggg gacttcatca atactcttta acggtattcc taatttttcc gcttgttctt
    38461 ttgtcgcatt tgaagtagta actcctgtga tacgtaaacc ttcttcacgc atacggcgac
    38521 caatctcttc taccatataa taggcggttg aaccggtccc gagacctacg atcatcccgt
    38581 cctttacgaa tttcgcggct tcaatgccag ctaattgttt taaattcatc tttgcgtcca
    38641 ccttttttta gtttgagcat cgtgctttcc tcactatttt agcgtgattt acggtaaaaa
    38701 gataccattc ttttttattc caataaagct ttttcaaaaa aaattgcatc tcttgttgac
    38761 atgttttttc attcgtgata ttctaacaaa ggtgctttat ctacaggttt ctgtgaagaa
    38821 acgtgctgac tgtttatcaa agcatatttg ataaggatgc agacattgca tttatttttt
    38881 atcacaaaaa aagaaccacc tggatgtgtg gaactagacg caaatcgtgg gaaggaggaa
    38941 acaaggaatg cctacaatta accaattagt acgtaaacct cgtaaatcaa aggtggaaaa
    39001 atctaattca cctgctttga acaaaggata taacagcttt aagaaaactc aaactaacgt
    39061 aaactcacct caaaaacgtg gggtagcaac tcgtgtgggt acaatgacac ctaaaaaacc
    39121 gaactcagct ttacgtaaat atgcacgtgt tcgtttgtca aacttaattg aagttactgc
    39181 ttatatccca gggattggtc ataacttaca agaacacagt gttgtattat tacgcggtgg
    39241 tcgtgtaaaa gacttaccag gggtacgtta ccatatcgtt cgcggtgctt tagatactgc
    39301 tggtgttaac gaccgtaaac aaagccgttc taaatacgga actaaaaaac ctaaagctta
    39361 attttaatta ttaaacaaat gaaacttgct tctactatat agaagtaatt actatgaaca
    39421 atatttcgga aggaggagtt acggatgcca cgtaaaggtc ctgttgcaaa acgtgatgtt
    39481 ttaccagatc ctatttataa ctcaaaatta gtaactcgct tgatcaaccg tgtaatggtt
    39541 gacggaaaac gcgggattgc agctaacatt atctataatg cctttgactt gatcaaagaa
    39601 tctacaggta acgatccatt agaagtgttt gaacaagcaa tgaaaaacgt tcaacctgtt
    39661 cttgaagtta aagcacgtcg tgttgggggt tcaaactacc aagtaccagt tgaagttcgc
    39721 cctgaacgcc gcgttactct aggtcttcgt tgggtagtaa actacgctcg cttgcgcggt
    39781 gaacacacaa tggaagaacg cttagcaaaa gaaatcatgg atgctgcaaa caacacaggt
    39841 gcttctgtta aaaaacgtga agacactcat aaaatggctg atgccaaccg tgcgtttgct
    39901 cactatcgct ggtaagattc tctctgtttg gtcggctttt ataagtcgac ctcagatagt
    39961 gtccttattt ttagcaacta gatagtaaag agaggagaaa caaggagaat gaccagagaa
    40021 ttttctttac aaaacactcg taatatcggt atcatggccc acatcgatgc tggtaaaacg
    40081 actgctactg aacgtatctt gtactatact ggtaaaatcc ataaaattgg tgaaactcat
    40141 gaaggagctt cacaaatgga ctggatggaa caagaacaag aacgtggtat tacgatcact
    40201 tctgctgcta ctacagcaca atggaagggt caccgaatca acatcatcga cacaccagga
    40261 cacgtagact tcacagttga agttgaacgt tcattgcgtg tacttgatgg tgctgtaact
    40321 gttcttgatg cacaatcagg tgttgaacct caaactgaaa cagtttggcg tcaagcaaca
    40381 acttatggtg tacctcgtat cgtatttgca aacaaaatgg acaagatcgg tgctgacttc
    40441 ttatattcag tatcaacttt acatgaccgt ttgcaagcaa acgctcaccc aatccaatta
    40501 ccaattggtg cggaagacga cttcacagga attatcgacc ttgtaacaat gaaggctgaa
    40561 atgtatacaa acgatcttgg aacagagatc gaagaaacag aaattcctga agaataccgc
    40621 gaattagctg aagaatggcg cgaaaaattg gttgaagctg tagctgaaac tgatgaagaa
    40681 cttactttga aatacttaga aggtgaagaa atcactgaag ctgagttaaa agaaggtatc
    40741 cgccgcgcaa cagttaacgt agaattctac ccagtactat gtggttcagc atttaagaac
    40801 aaaggggttc aattactatt ggacgctgtt cttgattact tgccatcacc gttagatatc
    40861 ccagctatca aagggattga ccctaaaact gatgaagaag tagaacgtcc tgcagacgac
    40921 agcgctcctt tctcagcttt agcatttaaa gttatgactg acccattcgt aggtcgttta
    40981 actttcttcc gtgtgtactc tggtgtttta caatcaggtt catacgtaca aaacgcaaca
    41041 aaaggcaaac gtgaacgtgt tggtcgtatc ctacagatgc atgccaactc tcgttcagaa
    41101 atctctgaag tttacgctgg agatatcgct gctgctgttg gtttgaaaga cacaactact
    41161 ggggacacac tatgtgatga aaagagtcta gttattcttg aatccatgga attcccagaa
    41221 ccagttatcc aagtcgctat tgaacctaaa tcaaaagctg accaagataa aatgggtgtg
    41281 gctttacaaa aactatctga agaagatcct actttccgtg ctgaaacaaa cgtggaaaca
    41341 ggcgaaacaa tcatcgctgg tatgggtgaa cttcacttag atatcatcgt tgaccgtatg
    41401 cgtcgtgaat tcaaagttga agctaacgta ggtgcgcctc aagtatctta ccgtgaaact
    41461 ttccgtgctg gcactcaagc cgaaggtaag tttgtacgtc agtctggtgg taaaggtcaa
    41521 tacggtcacg tatggattga atttacacca aatgaagaag gtgctggttt cgaatttgaa
    41581 aatgcgatcg tcggtggggt tgttcctcgt gaatacattc cagctgttga aactggtttg
    41641 aaagatgcta tggaaaatgg tgtcttagct ggctatccat tagtagatat caaagctaaa
    41701 ctttacgatg gttcatacca tgatgtcgat tcaaatgaaa ctgccttccg tgttgctgct
    41761 tctatggcat tacgtgcagc agctaagaaa gctaatccag taatccttga accaatcatg
    41821 gctgtagaag ttgttatccc tgaagattat ttaggtgatg ttatgggtca cgtaactgct
    41881 cgtcgtggac gtgttgaagg tatggaagct cgcgctggcg gccaacaagt tgttcgtgcg
    41941 atggttccac ttgctgaaat gtttggttat gctacaactc ttcgttctgc tactcaaggt
    42001 cgtggtacat ttacaatgac atttgaccac tacgaagatg taccaaaatc agtacaagaa
    42061 gaaatcatta agaaaaacgg cggaaaagct gaataatttc ttaaaaccgg atagtcctgc
    42121 aaagagatta tccaaagaga ctatattttt aatatagttt cgtgtaaaat aattatcgat
    42181 gatatgggca tgtggtgtac cttgtgtaca tcatatacct atcagacaaa taaaaaatat
    42241 attgtatttt taggaggaca ttttaaaatg gcaaaagaaa aatttgaccg ttctaaacca
    42301 cacgttaaca ttggtactat cggacacgtt gaccatggta aaactacatt aacagctgca
    42361 atcacaactg tactatctaa gaaaaacggc ggccaagcta tggcttacga tcaaatcgat
    42421 ggtgctccag aagaacgcga acgcggaatc acaatctcaa cagctcacgt tgagtatgaa
    42481 acagatacac gccactacgc tcacgttgac tgcccaggac acgcggatta cgttaaaaac
    42541 atgatcactg gtgctgctca aatggacgga gctatcttgg tagtttctgc tgctgacggc
    42601 ccaatgcctc aaactcgtga acacatccta ttgtctcgtc aagttggtgt tccttacatc
    42661 gttgtattct tgaacaaagt agacatggtt gatgacgaag aattactaga attagttgaa
    42721 atggaagttc gtgacctatt aacagaatac gaattccctg gtgacgatgt tcctgtagtt
    42781 gctggatcag ctttgaaagc tctagaaggc gacgcttcat acgaagaaaa aattcttgaa
    42841 ttaatggctg cagttgacga atacatccca actccagaac gtgacaacga caaaccattc
    42901 atgatgccag ttgaagacgt gttctcaatt actggacgtg gtactgttgc tacaggtcgt
    42961 gttgaacgtg gacaagttcg cgttggtgac gaagttgaag ttgttggtat tgctgaagaa
    43021 acttcaaaaa caacagttac tggtgttgaa atgttccgta aattgttaga ctacgctgaa
    43081 gctggagaca acattggtgc tttactacgt ggtgttgcac gtgaagacat ccaacgtgga
    43141 caagttttag ctaaaccagg tacaatcaca cctcatacaa aattctctgc agaagtatac
    43201 gtgttgacaa aagaagaagg tggacgtcat actccattct tcactaacta ccgtccacaa
    43261 ttctacttcc gtacaactga cgtaacaggt gttgttgaat taccagaagg aactgaaatg
    43321 gttatgcctg gcgacaacgt aacaatggaa gttgaattaa tccacccaat cgctatcgaa
    43381 aacggtacta aattctcaat ccgtgaaggc ggacgtacag ttggtgccgg tgtcgttaca
    43441 gaaatcaaag cttaattcac ttaagtttta aagtaaagca acatttattc ggacgtaatc
    43501 gctcggaacg aaggtcttag gatctttgtt ccgagctttt ttatttattg caggatcagg
    43561 aaaaaagaca ggagtattat aaatagaaga aacacgaaat aaaagagtca gtattttcta
    43621 aatgaaactt tatgaaaaca aaatgttttt tacaagaaaa agccttgctt tgtgagttta
    43681 tatatattat aatgacaaag gtgcgtttac tttagtgaat tgcacagacg taatcagaat
    43741 gatttcgtcg gctaagaaac gagaggttgc gacacgcccg gacgctttgc cacgaacgag
    43801 cgtgacggaa attttcgtgg agctatgtct acttttcaaa ataggcgaag gagggaacaa
    43861 gatggcaaaa caaaaaattc gtatccgttt aaaagcgtat gaacaccgta ttttagatca
    43921 atcagcggat aaaatcgtgg aaactgcaaa aagaactgga gctagcgtgt ctggtccaat
    43981 tccattacca actgaacgca gtctttacac aatcatccgt gcgactcata aatacaaaga
    44041 ttcacgcgaa caattcgaaa tgcgtacaca caaacgtctt atcgacattg tgaacccaac
    44101 accaaaaact gttgatgctt tgatgaagct agacttacca tctggtgtaa acatcgaaat
    44161 caaattataa aactaaaaca aaaataatgg aggtgtactc atgaccaaag gaatcttagg
    44221 gaaaaaagtg ggaatgacac aaatcttcac tgaatctggt gaattaattc cagtaactgt
    44281 tgtagaagct actccaaacg tagtactaca agtgaaaaca atggaaacgg atggctacga
    44341 agctattcaa gttggttacc aagatatgcg tgaagtttta tcaaacaaac ctgcgaaagg
    44401 tcatgttgca aaagcaaaca cggctcctaa gcgcttcatt cgtgaattca aaaatgttga
    44461 gctaggagaa tatgaagtag gaaaagaaat tacagtagat gttttccaag caggagacat
    44521 tattgatgta acaggtacta cgaaaggtaa aggattccaa ggggttatca aacgccacgg
    44581 acaaagccgc ggaccaatgg ctcacggttc tcgttaccat cgtcgtcctg ggtcaatggg
    44641 tccagttgca cctaaccgtg tatttaaaaa caaacgtctt gctggccgta tgggtggcaa
    44701 ccgcgtaact atccaaaact tggaagttgt acgtgtcgat gcagaaagaa atgttatctt
    44761 gatcaaaggt aatgttcctg gagctaaaaa atctttaatt actatcaaat cagctgtgaa
    44821 agctaaataa ttgtaggaag aaaggaggaa ctaaggaatg ccgaatgtag cattattcaa
    44881 acaagatgga agccaaaacg gtgaaatcac acttaacgaa gaaatcttcg gaattgaacc
    44941 taatgaaagt gttgtttacg atgcaatcgt aatgcaacgt gcgtcattaa gacaaggaac
    45001 acacgcggtt aaaaaccgta gcgctgttcg cggcggcgga cgtaaaccat ggcgtcaaaa
    45061 aggaacaggt cgtgcacgtc aaggatctat ccgctcacca caatggcgtg gaggtggcgt
    45121 agtctttgga ccaacaccac gttcttacag ctacaaactt cctaaaaaag ttcgtcgttt
    45181 agcaatgaaa tctgtattgt cagaaaaagt tgctgaaaac aacttggtag caatcgaagg
    45241 cttgaacttc gacgcaccaa aaacaaaaga attcaaacaa gttcttgcta acttatctat
    45301 cgactctaaa gtattggttg ttctagaaaa aggtaacgac tttgctgctt tatcagcacg
    45361 taacttacca aacgtttctg tagtaacttc tgataatgtg agtgtgctag acgttgtatc
    45421 aaatacaaaa gtgttagcaa cacaaactgc tcttactcaa attgaggagg tgcttgcata
    45481 atgaacttac tagacgtaat caaacgccca gtgatcactg aaaaatcaat gcttgccatg
    45541 gatgacaaga aatacacttt tgaagtggac actcgcgcaa acaaaacttt agtaaaacaa
    45601 gcggtagaag ctgcttttga cgttaaagtc aaaaacgtga acatcgtgaa cgtacgtgcg
    45661 aaattcaaac gtatgggcaa atatgcagga tatacaaaaa aacgtcgcaa agcgatcgtt
    45721 acattgactg aagattcaaa agaaatccaa ttattcgaag ctgctgaata agcactaata
    45781 gataactcat taaattagga gggaaaaacg tggcgattaa aaagtacaaa cctacctcaa
    45841 atggtcgtcg taacatgaca ggttctgatt ttgctgaaat cacaacatca acacctgaaa
    45901 aatcattgtt acaaccattg aaaaaccatg ctggacgtaa caacaacggc cgcatcactg
    45961 tacgtcatca aggtggcgga cacaaacgcc aatatcgcgt gatcgacttc aaacgtaaca
    46021 aagataacgt tgttgcaact gttcaaacga tcgaatatga tccaaaccgt tcagctaaca
    46081 tcgcgttagt acactatgaa gatggagtga aagcttacat cttagcacct aaaggactag
    46141 aagtgggtat gaaacttgtt tcaggtccag aagcagatat caaagtcgga aatgctcttc
    46201 cattagaaaa cattccagtt ggtactgtta tccacaacat tgaaatgaaa cctggtaaag
    46261 gtggacaatt gatccgttct gctggtacaa gtgctcaagt acttggtaaa gaaggcaaat
    46321 acgtattgat ccgcttgaac tctggtgaag ttcgtatgat cttagctgca tgccgtgcta
    46381 caatcggttc tgtaggtaac gaacaacacg aattaatcaa catcggtaaa gctggacgct
    46441 ctcgttggat gcgtaaacgc ccaactgtac gtggtagcgt aatgaaccct aatgatcacc
    46501 cacacggtgg tggtgaaggt aaagctccta tcggacgtaa agcaccagtt tctccttggg
    46561 gtcaaccagc tcttggttac aaaactcgta acaaaaaagc taaatcagac aaacttattg
    46621 ttcgtcgtcg caaaaataaa taattacttt gaccatgtgt cgcacatttt gagaggaggt
    46681 tcaccatggg tcgtagttta aagaaaggac cttttgtcga tgagcattta atgaaaaaag
    46741 ttgaagctca agcaggggtt gaaaagaaaa aagttatcaa aacttggtca cgccgttcaa
    46801 cagttttccc aagttttgtt ggatatacca tcgcagttta tgatggacgt aaacatgtac
    46861 cagtttacat ccaagaagac atggtaggac acaaattagg tgaatttgca cctacaagaa
    46921 cttatcgtgg acatgctgct gacgataaga aaacgaaacg ctaatttgag gggaggataa
    46981 atccaaatgg cagaacaaat cacatcagct aaagcaactg caaaaacagt tcgcacttca
    47041 cctcgaaaag cccgtttagt aattgacctt atcagaggta aaagtgtcgc agatgcaatt
    47101 tcaatcttga aattcacacc aaacaaatct gctggaatca ttgaaaaagt attgatgtca
    47161 gcagttgcga atgcagaaaa taactttgac ttagatgttg aaaacttggt agtaagcgaa
    47221 gcttttgtta acgaaggacc tacaatgaaa cgtttccgtc ctcgtgcaaa aggatcagct
    47281 tctccaatca acaaacgtac aagtcatatc acggtagtcg tatcagaaaa ataaggaggg
    47341 ataatcagtg ggtcaaaaag tacatccaat tggaatgcgt gtaggcatca tccgcgactg
    47401 ggatgctaaa tggtatgctg aaaaagagta tgctgagttc ttacacgaag atttaagaat
    47461 ccgtaaattt atttcaacta aacttgctga tgctgctgta tcaacagttg aaatcgaacg
    47521 cgcaacaggt cgcgtaaaca tttcaattca cacagctaaa ccaggtatgg ttattggtaa
    47581 aggcggttct gaagtcgaaa gcctaagaaa agaattaaac aaattaactg gtaaaagaat
    47641 ccatatcaat atcgtggaaa tcaaaaaacc agatctagat gcaaaattag taggtgaagg
    47701 aatcgcacgt caattagaaa accgtgttgc tttccgtcgc gctcaaaaac aagccatcca
    47761 acgctcaatg cgtgctggcg ctcaagggat caaaactcaa gtatctggtc gtctaaacgg
    47821 agcagatatc gctcgttcag aaggatactc agaaggaact gttcctcttc atactttacg
    47881 tgcggacatt gattacgcat gggaagaagc agatacaaca tacggaaaac taggagttaa
    47941 agtgtggatc tatcgtggag aaattcttcc aactaaaaaa aacactgaga aaggagggaa
    48001 ataatcatgt tagtacctaa acgtgtaaaa caccgtcgtg aattccgcgg aaaaatgcgc
    48061 ggggaagcta aaggcggaaa agaagtagca ttcggtgaat acggtttgca agctgttgat
    48121 tcacattgga tcacaaaccg ccaaatcgaa gctgctcgta tcgcaatgac tcgttacatg
    48181 aaacgtggtg ggaaagtatg gattaaaatt ttccctcaca aatcttatac tgccaaagca
    48241 attggggtac gtatgggttc tggtaaaggg gcacctgaag gatgggttgc accagtaaaa
    48301 cgtggtaaaa tcatgtttga aatcgcaggc gttcctgaag aagtagctcg tgaagcgtta
    48361 cgtctagctt ctcacaaatt accaatgaaa actaagatcg taaaacgtga ggaaatgggt
    48421 ggtgaatcga atgaaggtta aagaaatcag agaattaacc actgccgaaa tgcttgatca
    48481 agaaaaacaa ttaaaagaag aattgtttaa tcttagattc caattagcaa caggtcaatt
    48541 agaaaacact gcacgtatta aagaagtacg taaatcgatt gcacgcatca aaactgtgtt
    48601 gcgtgaacaa gctaagtaat tatggaagga ggccattaag cgtatgactg aaggaagaaa
    48661 tcaacgcaaa gtttatcaag gtcgcgtggt ttcagacaaa atggataaaa caattaccgt
    48721 tgctgtcgaa acaaagaaaa accaccctat ctatggcaaa cgcatgaact attctaagaa
    48781 atacaaagtg catgatgaaa acaacacagc aaaagttggc gacatcgtga gaattatgga
    48841 aactcgtcca ttatcagcta caaaacgttt ccgtttgttg gaagtagtcg aagaagcagt
    48901 tattatctaa taacacgaga ttttcctata tagattgaat gcaaaatctg aaaggaggat
    48961 acacaacgtg atccaagcag aaagtcgttt aaaagtcgct gataactcag gcgcacgtga
    49021 aattttgacg atcaaagtcc ttggtggatc tggtcgtaaa actgctaaca tcggtgatgt
    49081 gatcgttgct acggttaaac aagcaacgcc aggtggggtt gtcaaaaaag gtgacgtcgt
    49141 taaagccgtt atcgttcgaa caaaatcagg agctcgtcgt acagacggtt catatattaa
    49201 atttgatgaa aatgctgcag tgattattcg tgatgataaa agccctcgtg gaacacgtat
    49261 ctttgggcca gttgcacgtg aactacgtga aaacaacttc atgaagatcg tttcactagc
    49321 accagaagtt ttataatctt gagacactta tcaaaggagg tgcgaaacag ttatgtttgt
    49381 taaaaaaggc gataaagtta aagttatcac tggaaaagac aaaaacaaag aaggcgttgt
    49441 actagcagcg ttcccgaaaa aagataaagt tattgtcgaa ggtgtaaatg tcgttaaaaa
    49501 acaccaaaaa ccttctcaag ctgctcctca aggtggaatt gttgagatgg aagcgccaat
    49561 tcatgtttct aacgtgatgg tggttgactc tactggtgta gctggccgag ttggctacaa
    49621 agaagtagac ggcaaaaaag tccgtgtttc taaaaaaacc ggtgaagttt tagataaata
    49681 aaagtttaag gaaggagggt cttactgaat gaaccgccta aaagaaaaat atcttaaaga
    49741 agtaactcca tcattgatgg aaaaatttaa ctatagctct gttatgcaaa cacctaaagt
    49801 tgaaaaaatc gtcatcaaca tgggtgttgg tgatgcggta tcaaacgcta aaaacttaga
    49861 taaagcagtt gaagaattaa ctttgatcac tggtcaaaaa ccaatgatta caaaagctaa
    49921 aaaatcaatc gctggattcc gtttacgtga aggaatgcca attggtgcaa aagttacatt
    49981 gcgcggagaa agaatgtacg aattcttaga caaattggtt tctgtttcac taccacgtgt
    50041 acgtgacttc catggtgtaa gtaaaaaagc ctttgacggt cgtggaaact atactttagg
    50101 tattaaagaa caattgatct tcccagaagt agattatgat ttagtagata aagtacgtgg
    50161 tatggacatc gttattgtaa caacagcaaa ctctgatgaa gaatctcgtg agttgttgac
    50221 acaattaggc atgccattcc aaaaataatt aaaggaggcg aactacgtgg ctaaaaaatc
    50281 aatgattgct aaaaacaaac gtcctgcaaa attttcaaca caagcttata ctcgttgcga
    50341 acgttgcgga cgtccacatt cagtttatcg taagttccat ctttgccgta tttgcttccg
    50401 cgaacttgcc tataaaggtc aaattcccgg cgtgaagaaa gctagctggt aaaaagtaaa
    50461 ttcgcataag aaggaggtaa aagatcaatg gtcatgacag atccaattgc agattttcta
    50521 actcgtatcc gtaacgcaaa catggttaaa catgagtctt tagaagtacc tgcatcaaaa
    50581 attaaacgtg acatcgctga aatcttgaaa cgtgaaggtt tcgttcgtga tgttgaatac
    50641 atcgaagatg acaaacaagg cgtgatccgt gttttcctaa aatttggtaa aaacggcgaa
    50701 cgtgttatca caaacttaaa acgtatctct aaaccaggtt tgcgtgctta tgtcaaagct
    50761 gacgaagtac caaaagtatt gaacggttta ggtatcgcaa tcatttcgac ttctgaaggt
    50821 gttgtcactg ataaagaagc tcgtgaaaaa aatatcggcg gcgaagttat cgcttacgta
    50881 tggtaatcaa gtagaatcta caaggaggtg tctttaagtg agccgtatcg gaaataaagt
    50941 cgttgttatc cctgaaggag taacagttac tcaagacgga aacaacgtta cagttaaagg
    51001 accaaaaggt gaattgactc gtactttttc agcagatatc aaaatgaata tcgaaggaaa
    51061 cgaagtaact ttcactcgtc caaacgacag taaagaaatg aaaacaattc atggaacaac
    51121 tcgtgcgaac ttcaacaaca tggttgtagg tgtcagcgaa ggtttccaaa aagcgttaga
    51181 actaatcggg gttgggtacc gtgcacaatt acaaggatca aaacttgtat tgaacgttgg
    51241 ttactcacat ccagtagaaa tcacaccacc agctggagta actgttgaag taccagctaa
    51301 cacacaagta attgttaaag gtgcgaacaa agaagaagtt ggcgaattag ctgcaaacat
    51361 tcgtggaact cgtcctccag aaccttataa aggtaaaggt attcgttatg ttggcgaata
    51421 tgtacgccgt aaagaaggta aaactggtaa ataatcgttt agaaaaattg catagaagcc
    51481 agcagcagga aaaaggcatt tggctgaagt ttaccttcaa aaaaatacat ttttacttgt
    51541 gccgcagctt ctatttttcg aaacgtattt actgcttgaa atagtagtac aataaaaata
    51601 aagaggtgac aattgtgatt acaaaaccag ataagaacaa aacacgtcaa aagagacatc
    51661 gtcgtgtacg taacaatatc tctggtactg ctgagcgccc acgcttgaac gtttttcgtt
    51721 ctaacaaaaa catctacgct caaattattg atgacgtagc gggtgtaacg ctagcaagtg
    51781 cctctacctt ggataaagaa atttcaggtg gaacaaaaac agaagcagca caagctgtcg
    51841 gtaaactagt tgctgaacgt gcagctgaaa aaggcattaa agtagtagtc tttgaccgtg
    51901 gtggatacct ttaccatggc cgtgtgcaag ctttagctga agctgctcgc gaaaatggac
    51961 tagaatttta gaagaaggag gaataccatt catggtttat atcgatccaa aacatttgga
    52021 attagaagac cgcgttgttg caattaaccg tgtaacaaaa gttgttaaag gtggacgtcg
    52081 tctacgtttt gctgctttag ttgttgtcgg tgacaaaaac ggacacgtag ggtttggtac
    52141 aggtaaagct caagaagttc ctgaagcaat ccgtaaagca attgaagatg cgaagaaaaa
    52201 cttagttgaa gtacctatgg ttggttcaac aatcccacac gaagtaatcg gtgcttttag
    52261 tggtggtaga atcctaatga aacctgctgt agaaggttct ggggttgctg ctggtggacc
    52321 agttcgtgcc gtattagaat tagctggggt agcagatatc acttctaaat ctttaggctc
    52381 aaatacacca atcaacgttg ttcgcgcaac agttgaaggt ttgaaacaat tgaaacgtgc
    52441 agaagaagtt gcagaacttc gcggcaaatc agttgaagaa ttaatcggat aaggaggaca
    52501 acaataatgg ctgaattaaa agttacttta aaacgcagta ttatcggacg tcctcaaaac
    52561 caacgcgata cagttaaagc gttaggtctt acaaagatta acagttcagt ggttaagcct
    52621 tctaatgaag caattaaagg catgatcaat actgtttctc acctagtgga cgttgaagaa
    52681 atttaattta gaaaaatcat aactagaaca ttaaggaggt gccaaaccta tgaaacttca
    52741 tgaattaaaa cctgctgaag gttcacgcca agtacgtaac cgtgttggtc gtggtacttc
    52801 atctggtaac ggaaaaactg ccggacgcgg acaaaaagga caaaaagctc gttcaggcgg
    52861 cggtgtgcgt ttaggatttg aagggggaca aacaccattg ttccgtcgtt taccaaaacg
    52921 aggattcaca aacgtgaacc gtaaagacta tgcagtcatt aatcttgatg tattgaaccg
    52981 ctttgaagac ggagctgaag taactcctgt tgctttagtt gaagctggaa tcgtgaaaaa
    53041 cgaaaaagct ggaatcaaag tattagctaa tggggaacta aacaagaaat taactgtgaa
    53101 agcagcaaaa ttctctaaag cagctcaaga agcaattgaa gcggctggtg gatcaatcga
    53161 ggtgatctaa tgtttagact attaaaagat gcttttaaag taaaagacat tagatcgaaa
    53221 atcctattta ctgtatttgt gttgtttgta tttcgcctag gtgcacatat tactgtacca
    53281 ggcgtaaatg ctgcttcatt gcaaaacctt tcttctttgc catttttcaa catgttgaac
    53341 ttggtaagtg gtagtgcgat gcaaaacttt tccattttct caatgggggt ttcaccatac
    53401 attactgctt ctatcgtcat tcagcttctt caaatggaca tcgtgcctcg atttgttgaa
    53461 tggtcgaaac aaggggaagt tggtcgtaaa aaactgaatc aagcgactcg atatctgaca
    53521 ttagtattgg catttatcca atctgtcggt atcactgctg gattcaatca atacgctcaa
    53581 ttaggtttcg tgaataatcc taacgtagca acttacgtaa cgatcggttt gattctaaca
    53641 gccggtacga tgtttgttac ttggctagga gaacagatca cagaaaaagg tatcggaaat
    53701 ggcgtatcaa tgatcatttt tgcaggtatc atttctagat tgcctgaaag tatcagagaa
    53761 atttatgaag attactttat aaatattgat ccttcagaca tatggaaatc tgctattttt
    53821 gtggccattt tactagtagc ggtcttgttg atcgtgacat tcgtaacatt tttccaacaa
    53881 gctgaacgca agatcccgat ccaatatacg aaacgcgtag ctggcgcgcc tacaagcagc
    53941 tatctgccgt tgaaagtaaa tgcagctgga gttattccag ttatctttgc tagttcgttt
    54001 attgctacgc caaatgctgt tttacaagca ttgagcggta gattcggttc tgaaaactgg
    54061 tacaaagtga tgatggagat ctttaactat aatacagcac ctggtgctac gatttatacg
    54121 attctgatcg ttgccttcac tttcttctac gcctttgttc aagtaaaccc tgagaaatta
    54181 gcggaaaact tgcaaaagca aggaagttat ataccaagcg tacgccctgg taaggggact
    54241 gaagagtatg tctcaagatt actgatgcgt ttaagtacag ttggtgcagt cttccttggt
    54301 ttagtggcat tgcttccaat cattgctcaa atggtttggg atcttccaca atcaatcgga
    54361 ttaggcggta caagcttact gatcgttatc ggtgtagctt tagaaactgc gaaacagtta
    54421 gaaggcttaa tgctgaaacg taaatatgtt ggattcattg agtaagaaag cgtgttgagg
    54481 tttcccctca acacacgttc tcacacattt attaggaggg aaaacaatga acctcatttt
    54541 aatggggctg ccaggcgcag gtaaaggaac acaagctgaa aaaatcattg atgcttatgg
    54601 tattccgcac atctcaacag gagatatgtt ccgcgcagcg atgcaaaacg aaacagctct
    54661 tggcctggaa gcaaagtctt atatggataa aggtgcatta gttcctgatg aagtaacaaa
    54721 tggaatcgtg aaagagcgac tagctgaacc agatacagag aaaggcttct tattagatgg
    54781 ctttccacgt acgctagatc aagcaaaagc tctggacgca atgctaaaag atttgaataa
    54841 aaaaattgat gctgtcatcg atatccatgt tggtgaagaa atcttggtcg aacgtctagc
    54901 cggccgattt atctgcagca attgtggagc aacttaccat aaaattttca accctacaaa
    54961 agttgaagac acatgtgatc gttgcggtgg gcatgaattc tatcaaagag aagatgataa
    55021 acctgagacg gttaaaaatc gtctggctat caacatcaaa aatagtgaac caatcttggc
    55081 ttattataaa gaacaaggtt tgctaaacac tattgatggt gctcgtgaaa tcgatgctgt
    55141 atttgcagat gtacaaaaaa tcattgaaaa atagcacgat tgcccgtagc cgacttgcat
    55201 tatgcagtta ctcttgtcaa gttcaataaa ttatgataga atatgtcagt ccgacttcta
    55261 gagaatcctc tagatgatcc attttgagaa ttttgaggtg ggaactgcag tttccgccat
    55321 tttatcgtgt gaaaatgcga aacaagtaca aggaggtact gtgcgtggca aaagaagata
    55381 tgattgaagt cgaaggtaca gtcgtcgaaa ctttgccgaa tgcaatgttt aaagttgaac
    55441 tagaaaacgg acaccaagtt cttgctactg tttcaggtaa aattcgtatg cattacatcc
    55501 gtatcttacc tggtgacaaa gtaacggttg aattgtctcc atacgatctt aaccgtggcc
    55561 gtattactta tcgctttaaa taattgtact ccgtaaaact acaggaggta ttatcatgaa
    55621 agtaagacca tcagtaaaac caatgtgcga acattgtaaa gtaattcgtc gtaaaggacg
    55681 cgttatggtg atttgcccag caaatccaaa acataaacaa cgtcaaggat aattggaggt
    55741 gctataaata tggctcgtat tgcaggagta gatattcctc gtgataaacg tgtagtagtt
    55801 tcacttactt atatctatgg tattggtaac actactgcta aaaagatctt agctgatgct
    55861 ggtgtatctg aagatgttcg cgttcgtgaa ttaacgaatg aacaaacaga tgctatccgt
    55921 gcagaagtag ataaattaaa agttgaaggg gatcttcgtc gtgaagtgaa cttgaacatc
    55981 aaacgtttga tggaaatcgg ttcttaccgt ggaatccgtc atcgccgtgg attgcctgtt
    56041 cgtggacaaa acacgaaaaa caatgcacgt actcgtaaag gcccagctcg cgctatcgct
    56101 ggcaagaaaa aataattctt aagtgaagga ggttaaaact tcatggcagc aaaaaaagtg
    56161 aatcgtaaac gccgtgtgaa gaagaatata gaagcaggta ttgcacatat ccattctaca
    56221 ttcaataaca ctatcatcat gatcactgat actcacggaa atgcattagc gtggtcatca
    56281 gctggttcat taggtttcaa aggaagcaaa aaatcaactc cttttgccgc tcaaatggca
    56341 gcagaaactg ctacaaaagc agcaatggaa cacggattaa agactgttga agtaacagtt
    56401 aaaggacctg gttctggacg tgaagcagca attcgttcat tacaagctac aggtttagaa
    56461 gtgactgcaa ttcgtgacgt gactccagtt cctcataatg gtgcccgccc tccaaaacgc
    56521 cgtcgtgttt aatgagtgcc gctcattttg agttttatca gtaacgtcat tgaacaagac
    56581 acttttcgtt ttgaaagggg taaagataag aatgattgag ttcgaaaaac caagaatcgc
    56641 aaaaattgat gaagaaaaag attatggcaa gttcatcgtt gaacctcttg aaagagggta
    56701 tgggactact ttagggaatt ccctacgtcg tattttatta tcttctttgc caggtgctgc
    56761 catcactaat attcaaatcg atggtgtact gcatgaattc tctaccatca aaggtgttag
    56821 agaagacgtc actcaaatca tcttgaacat taaaggctta gcgctgaaaa tgtatggcca
    56881 agaagaaaaa acccttgaaa tcgatattac cggacctgct acagtaactg ctggcgatat
    56941 tatcgttgat agtgatgtag aaattcttaa caaagatatg tacatctgta gtgtctctga
    57001 aggagctacg ttccatgctc gcttaacagt gaaacctgga cgtggttatg ttcaagcaga
    57061 tgaaaataaa aaagaagata tgccaattgg cgttcttcca gtcgattcaa tctacacacc
    57121 tgttcgtcgt gtgaactatc aagttgagaa cacacgtgtt ggacaccgtg aagattttga
    57181 taaattgacg atggagattt ggacagatgg ttcaattgaa ccgttggaag caatgagttt
    57241 gtctgcgaaa atcatgactg aacatttgga tatttttgtg aacttaactg atgaagcaaa
    57301 aaatgctgaa atcatggtcg aaaaagaaga aacacaaaaa gaaaaaatgt tggaaatgac
    57361 gatcgaagag ttagacttgt ctgttcgctc ttacaattgt ttgaaacgtg caggaatcaa
    57421 tactgtacaa gaacttacaa ataaatctga gcctgaaatg atcaaagtcc gtaacttagg
    57481 acgtaaatca ttagaagaag ttaaagcaaa attgcacgac ttaggtttag gtttacgtaa
    57541 agaagattaa aaccttttac gaaggaggga aaccaacgtg agttatcgta aactaggacg
    57601 cacatctagc caacgtaaag cgatgttgcg tgatttaaca actgatttat taatcaacga
    57661 acgtattgtg actactgaag ctcgtgcgaa agaagttcgc tcaactgcag aaaaaatgat
    57721 cactttaggt aaacgcggag atttgcatgc acgtcgtcaa gctgcggctt tcgtacgtaa
    57781 tgaagttgcc agcgtgcgtg aagaaaatga ggacatcgtc attgaatcag ctttacaaaa
    57841 actgttcaac gatattgcac ctcgttacgc agaacgtcaa ggcggataca cacgcatttt
    57901 gaagacagaa ccaagacgcg gtgatggtgc accaatggtt gtcttagaac ttgtctaaaa
    57961 tcacactaat aacatcactt tatagatgat tcttttagag tgttatgatg ttggaagata
    58021 tttttccgag tctagctcag cgctgctcct caagcgaata tcgcttgggg agtaagcact
    58081 catcataaag tgttttttta taccttcaat tacctgtcat gacagatatg tttgaaggca
    58141 taaaaaaaca ttttaagcga gaaataattg aaaattttgt ctttttttga tagtgttagt
    58201 aggaacttta ggatgaagaa ggagtaatca tggagccaat tattgaatta gaaaagataa
    58261 attataaata ccagccagat gatcttcgcc ccgcattgaa agatgtctcc tttacaattg
    58321 ataaaggtga gtggatcgct attattggac acaatggttc aggaaaatcg acacttgcca
    58381 aaacgatcaa tggattgctt ctgccagaat cagggatcgt gaaagtggga aatcaaatat
    58441 tggatgaaga aaatatttgg acgatccgac agatggttgg aatggttttt caaaatccag
    58501 acaatcagtt tgttggttcg acagtagaag atgacgttgc ttttggtctt gaaaatcaag
    58561 ggattcccag agaagaaatg ctagtgcgtg tgaaagatgc acttgagaaa gttagaatgg
    58621 ctgagtttgc ttcacgcgag cctgctcgtt tatcaggagg gcaaaaacaa cgtgttgcca
    58681 ttgccggcgt ggttgcctta cgacctgata tcattatttt agatgaagca accagtatgc
    58741 tagatccaga aggtcgtgaa gaagtgatct ctacgatcaa gaagatcaaa gaagaaagtc
    58801 aattgaccgt tatatctatc actcatgata ttgatgaagc agctaatgcc aatcggatac
    58861 tagtgatgag acaaggcgaa cttgtccgtg aaggtacacc aaaagaaatt ttttctgctg
    58921 gtcctgaact gatcgactta ggtctagatc taccatttcc tgaaaaactg aagagcgcac
    58981 tgaaagaacg tggggttgat gtgcccagtg aatatatgac agaagaaagg atggtggatt
    59041 ggttatggac atccgttttg aacaagtaga cttcacttat cagccgaata caccatttga
    59101 acaaagagcc ttatttgaca tcaatatgac gatcaaagaa aacagttata ctgcattagt
    59161 agggcatacc ggaagcggga aatcaacctt acttcagcat ttgaatgcgc ttgttaagcc
    59221 aacaagcggt acagtccata ttggagaacg agatattcag ccggatacgg ataataagaa
    59281 tttaaagccc atccgaaaaa aagttggcat cgtctttcag tttccagaag cacagctatt
    59341 cgaagaaacg gtagcaaaag acattgcttt cggtcctaaa aactttggtg tcagcgaaga
    59401 agaagcacta gtcctagcaa aagaaacatt agaacaagtt gggctggatg aaagctattt
    59461 ggaacgttcg ccatttgaac tttcaggagg gcaaatgcgt agagtagcaa tcgctggtgt
    59521 gcttgccatg aggccggaag tacttgtatt ggatgaacca acggcaggac ttgatcccca
    59581 gggtagaaaa gaaatgatgg agatgttttg gcgtcttcat aaggaacagc agatcactat
    59641 tgtattagtt acgcatttaa tggatgatgt agccaatttt gcagattatg tctatgtgtt
    59701 ggaaaaggga cgaatcgtta atagcgggga gccgcaagag gtctttcaaa acattgaatg
    59761 gctaaaagaa aaacaactag gcgtacctac tgccaccgag tttgcagaag aattaatggc
    59821 taaagggatg aactttgcta ccttgccttt gacagctgaa gaattagcag acgctatcgt
    59881 ccattatgct ggaggaaatg cccatgatga ataaattgat atttggtcgt tatatgcctg
    59941 gagattcctt gatccatcga ttggatcccc gagctaaatt attagccagt ttttatttta
    60001 tcggaatcat ttttttagca aataattggg aaacgtacct tttgttggca tttttcacat
    60061 tactttctgt cttcttgtca aaagtagatt tgaaattttt tatccgaggc attcgcccat
    60121 tgatctggct aatcctcttc actgtagctt tgcaggtctt gtttacaagt ggcggagaaa
    60181 cttattggag ttggggtgtt ttccatatca ctgaatttgg tgtgatgaac ggcctcttta
    60241 ttttctgtcg attcgtgttg atcattttta tgtcgactct actcacgctt actacaccgc
    60301 ctttggaatt atcggatgcg attgagtact tgcttcgtcc attgaaagcc gtacggttcc
    60361 cagtccacga aatttcattg atgctgtcga ttgctcttcg ttttgtgcct acattgatgg
    60421 acgaaacaga aaagatcatg aacgctcagc gcgctcgcgg tgttgatttt ggtgaaggaa
    60481 acctagttca gaaaatgaaa gcagtcattc ctttgctgat tcctttattt gtcagcagct
    60541 tcaaccgtgc ggaagatctt gcgactgcta tggaagcaag aggctacaaa ggtggggaag
    60601 gaagaacgaa atattgtgta ttgcattggc ataatagaga cacgatggtt atcattgctt
    60661 ttgtattatt aactgtgcta ctgatctttt tgagaggata aacgttcagt gggccgctat
    60721 ctattctttt cttgctgatc tgtttgcaag aaaggatgcg agcagtgtat gacaagaaat
    60781 attagggtct gtggcagact aaggtcacag gcctctttct tttatctgaa aagaaagaac
    60841 gaaaaaattt tataaaaaaa tcattattcc agataacctt ttaggaacaa aggagagaaa
    60901 aacatggtac gttacaaagc aatcattgca tacgacggaa caaattttaa tggattccaa
    60961 aaacagccaa atgggcgtac tgttcaagaa gaagtagaaa aaacattaca aaaaatggca
    61021 aatggaaaag aaatcacggt ctttggttcg ggaaggacag atgccggagt acatgcgatt
    61081 gggcaagtaa tccattttga ttatccagag gagcgtccgt tagaacgaat gcgtttcgcg
    61141 ctagataccc agtcaccaga ggatattgct gtaagacaag tagaaattgt ttcagaagac
    61201 ttccacgcaa gatatttggt caaagaaaag acgtatcaat ttcgagtgga tatagggaaa
    61261 ccacgcagtc cttttcgacg ccattatgca agttattttc cttaccctct tgatttggaa
    61321 aaaattcagc gggcgcttcc tgatttatta gggactcacg atttcacctc tttttgtgca
    61381 tcaggaagct cgatagagga taaagtacgt acgatctacg aggctaagat ggaggtaaat
    61441 gaaacaaaag acgaattgtt gtttacattt aggggaaatg gcttcttgta taagatgata
    61501 cggatcttag taggaacgct tttgaaaatt ggcaatggcc gattgcctga agatagtatc
    61561 ccagatatta ttgcgaaaaa agatcgtaat gcagcaggac ctacagcaca tcctgaagga
    61621 ctttatttgt atgaagtgaa atatgaataa gaggttgtga cagaagtggt cagcttcaag
    61681 aaataagaag gaatttacga aaattacttc tcaaaatttt gcaaaatttc ggcttatttt
    61741 cgaaggagct acttctggaa caccgtgaat cagaggttgt gaaaaagctg ccctgcatca
    61801 agtaataaga acaaccaaac aaaaatagct cgtcatattt ttcgtttggt tgggcttatt
    61861 accgcagatg caagcttttg aacaccgttt aaggaagagg ttgtgaaatc agcgttttga
    61921 cctgagtatt agagaaacaa acggaaaaat agttcctcat attttgccgt ttgttgagct
    61981 aataccgaag gtcagctgat tgaacaccgt ttaagaaaga ggtcgtgagc ctgtcattta
    62041 actctgagtc acaagtaaca atttcaaaaa acagcttctc atctttgatg aatatcgtga
    62101 cttgtggacg aggcgttgat aagtgaatca tctttttgtt acctattttt tctgtaacca
    62161 aaaaacgatg gaacgttgtt ttgattgccc ttaatgagga cagtcggaac aggtttgtca
    62221 tttttatatt taaatggcac aaatttttct aattatttgt catttagcgc tgaaaatttt
    62281 tgctatttat ctaaaaaagt gataactact taagatgaag cagaatattt acgccatacg
    62341 gcatacaacc gcgaaaaata taaaaaaaag aaaacgattg aacgcgtttt tgcagtcgca
    62401 aaggaaaagc atggaatgcg ctacatcaag tatcgagact tggaaaacaa tcaggtgtat
    62461 acgctgattg tttttgctgc aatgaatctg aaaaagttgt ccacttggca gttggaacat
    62521 atgtcttcat atcttttatt atacaaaaat agcaaaagca ccagtctaca ctcttagtaa
    62581 agaggaaact gatccttttg tctacattct taaagtactt aaactaagta ctttatttta
    62641 ctctttagga ttgatacagt agcatctatc cctttattaa taatctttta tttttttaaa
    62701 taaagatgtt gtctccatct tcaggcacta aaactttttc ggaaattcct ttttctttat
    62761 tgaaagactt taattcttct cttgacagtc cccaatggtt tacagcttcc atatgaacgg
    62821 caataattgt ggaatctggt attgctttat gcaattcata taaatcgtct ttccccataa
    62881 taagagattc tccaactaaa aaatgattat ctccagcatt tgctactatg atttctggat
    62941 tatactgatc aatagtttgt ttaacagctt cataccaaac tgtatctcct gtaaagtata
    63001 gtgtcttctc agtcgaatgt ttgaaaacaa taccgcaaac attacctaca taattcaaga
    63061 tttctcctct gccatgtttg ccttttgttt taaccaattg tatagattca aaaactgtgt
    63121 cttctcgtag tacctccaca tttttaaaac catatagtcg aatttcattc gcatcatttt
    63181 catcttgcac aaataatttt atttctttag gtaggacctc tttcgctata tcgtcccaat
    63241 gatctagatg taaatgtgtt acaataacag catcaatacc gttgataata tcttcgactg
    63301 gcattggcaa atcaactaga ggattcattt gatcttttct tggtgatgga aaaggacctt
    63361 tcgaaataaa tggtggaagt gttccttttt ccgctaacat tggatcaatt aaaaattttt
    63421 tacctccata gtctaagata gctgttgcat tacgaatgtg atgtatattc ataaacgttg
    63481 tctccttttt gttgatatga aatattttta gtataattca attccataca ataaataaac
    63541 cgaacaaaaa aagtctttta ctatttttac ttaatttatg aaaggttgtt taccatgtta
    63601 gaccaaacag atataaatat cattgaggaa ctatcaaaaa atagtcgaat cacaatgaaa
    63661 gaacttggag aaaaagtaca tttgactgga cccgctgtct cggcgagagt gacaaaacta
    63721 gaggaaagtg gagttattga aaattataca gtaaaattaa atatggaaaa gctagggttt
    63781 tcgattcacg cttttttaat tataattacg caaaatttaa a
//
LOCUS       DACCVZ010000005        61642 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.005, whole genome shotgun sequence.
ACCESSION   DACCVZ010000005 DACCVZ010000000
VERSION     DACCVZ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.005"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(56..1444)
                     /gene="ltrA"
                     /locus_tag="IVW63_000314"
     CDS             complement(56..1444)
                     /gene="ltrA"
                     /locus_tag="IVW63_000314"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP7858617.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
     gene            complement(2013..2390)
                     /locus_tag="IVW63_000315"
     CDS             complement(2013..2390)
                     /locus_tag="IVW63_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858618.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            2646..3374
                     /locus_tag="IVW63_000316"
     CDS             2646..3374
                     /locus_tag="IVW63_000316"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAP7858619.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            3374..3628
                     /gene="purS"
                     /locus_tag="IVW63_000317"
     CDS             3374..3628
                     /gene="purS"
                     /locus_tag="IVW63_000317"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HAP7858620.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            3630..4301
                     /gene="purQ"
                     /locus_tag="IVW63_000318"
     CDS             3630..4301
                     /gene="purQ"
                     /locus_tag="IVW63_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HAP7858621.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            4302..6524
                     /gene="purL"
                     /locus_tag="IVW63_000319"
     CDS             4302..6524
                     /gene="purL"
                     /locus_tag="IVW63_000319"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HAP7858622.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            6509..7948
                     /locus_tag="IVW63_000320"
     CDS             6509..7948
                     /locus_tag="IVW63_000320"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAP7858623.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            7980..9023
                     /locus_tag="IVW63_000321"
     CDS             7980..9023
                     /locus_tag="IVW63_000321"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAP7858624.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     LDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFAVGI
                     AEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLG
                     EELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPIL
                     PIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGKVIA
                     KEKHRVVFIGEER"
     gene            9020..9598
                     /gene="purN"
                     /locus_tag="IVW63_000322"
     CDS             9020..9598
                     /gene="purN"
                     /locus_tag="IVW63_000322"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAP7858625.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            9595..11130
                     /gene="purH"
                     /locus_tag="IVW63_000323"
     CDS             9595..11130
                     /gene="purH"
                     /locus_tag="IVW63_000323"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAP7858626.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            11146..12420
                     /gene="purD"
                     /locus_tag="IVW63_000324"
     CDS             11146..12420
                     /gene="purD"
                     /locus_tag="IVW63_000324"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAP7858627.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            12542..13456
                     /locus_tag="IVW63_000325"
     CDS             12542..13456
                     /locus_tag="IVW63_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAP7858628.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(13589..15154)
                     /locus_tag="IVW63_000326"
     CDS             complement(13589..15154)
                     /locus_tag="IVW63_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP7858629.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(15147..16598)
                     /locus_tag="IVW63_000327"
     CDS             complement(15147..16598)
                     /locus_tag="IVW63_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP7858630.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(16612..17628)
                     /locus_tag="IVW63_000328"
     CDS             complement(16612..17628)
                     /locus_tag="IVW63_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7858631.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            17848..18936
                     /locus_tag="IVW63_000329"
     CDS             17848..18936
                     /locus_tag="IVW63_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP7858632.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            18990..20516
                     /locus_tag="IVW63_000330"
     CDS             18990..20516
                     /locus_tag="IVW63_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAP7858633.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            20518..21723
                     /locus_tag="IVW63_000331"
     CDS             20518..21723
                     /locus_tag="IVW63_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7858634.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            21980..22957
                     /gene="guaC"
                     /locus_tag="IVW63_000332"
     CDS             21980..22957
                     /gene="guaC"
                     /locus_tag="IVW63_000332"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAP7858635.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            23221..24645
                     /locus_tag="IVW63_000333"
     CDS             23221..24645
                     /locus_tag="IVW63_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAP7858636.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            25106..26215
                     /gene="pdhA"
                     /locus_tag="IVW63_000334"
     CDS             25106..26215
                     /gene="pdhA"
                     /locus_tag="IVW63_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HAP7858637.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            26218..27195
                     /locus_tag="IVW63_000335"
     CDS             26218..27195
                     /locus_tag="IVW63_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAP7858638.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            27220..28863
                     /locus_tag="IVW63_000336"
     CDS             27220..28863
                     /locus_tag="IVW63_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005236379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HAP7858639.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            28871..30277
                     /gene="lpdA"
                     /locus_tag="IVW63_000337"
     CDS             28871..30277
                     /gene="lpdA"
                     /locus_tag="IVW63_000337"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAP7858640.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            30439..30714
                     /locus_tag="IVW63_000338"
     CDS             30439..30714
                     /locus_tag="IVW63_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HAP7858641.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            30720..31487
                     /locus_tag="IVW63_000339"
     CDS             30720..31487
                     /locus_tag="IVW63_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HAP7858642.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            31655..33484
                     /gene="typA"
                     /locus_tag="IVW63_000340"
     CDS             31655..33484
                     /gene="typA"
                     /locus_tag="IVW63_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAP7858643.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            33745..35517
                     /gene="recQ"
                     /locus_tag="IVW63_000341"
     CDS             33745..35517
                     /gene="recQ"
                     /locus_tag="IVW63_000341"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HAP7858644.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            35631..35933
                     /locus_tag="IVW63_000342"
     CDS             35631..35933
                     /locus_tag="IVW63_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HAP7858645.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            35936..37099
                     /locus_tag="IVW63_000343"
     CDS             35936..37099
                     /locus_tag="IVW63_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP7858646.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            37125..40553
                     /locus_tag="IVW63_000344"
     CDS             37125..40553
                     /locus_tag="IVW63_000344"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAP7858647.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            40574..41698
                     /locus_tag="IVW63_000345"
     CDS             40574..41698
                     /locus_tag="IVW63_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858648.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            41688..42125
                     /locus_tag="IVW63_000346"
     CDS             41688..42125
                     /locus_tag="IVW63_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAP7858649.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            42109..42447
                     /locus_tag="IVW63_000347"
     CDS             42109..42447
                     /locus_tag="IVW63_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HAP7858650.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            42566..43126
                     /gene="rsmD"
                     /locus_tag="IVW63_000348"
     CDS             42566..43126
                     /gene="rsmD"
                     /locus_tag="IVW63_000348"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAP7858651.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            43123..43614
                     /gene="coaD"
                     /locus_tag="IVW63_000349"
     CDS             43123..43614
                     /gene="coaD"
                     /locus_tag="IVW63_000349"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAP7858652.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            43604..44647
                     /locus_tag="IVW63_000350"
     CDS             43604..44647
                     /locus_tag="IVW63_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAP7858653.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            44806..45534
                     /locus_tag="IVW63_000351"
     CDS             44806..45534
                     /locus_tag="IVW63_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HAP7858654.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            45650..45895
                     /locus_tag="IVW63_000352"
     CDS             45650..45895
                     /locus_tag="IVW63_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP7858655.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            45892..46110
                     /locus_tag="IVW63_000353"
     CDS             45892..46110
                     /locus_tag="IVW63_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAP7858656.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            46246..46785
                     /locus_tag="IVW63_000354"
     CDS             46246..46785
                     /locus_tag="IVW63_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HAP7858657.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            46778..49051
                     /locus_tag="IVW63_000355"
     CDS             46778..49051
                     /locus_tag="IVW63_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HAP7858658.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            49089..50135
                     /gene="holA"
                     /locus_tag="IVW63_000356"
     CDS             49089..50135
                     /gene="holA"
                     /locus_tag="IVW63_000356"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAP7858659.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(50224..50478)
                     /locus_tag="IVW63_000357"
     CDS             complement(50224..50478)
                     /locus_tag="IVW63_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAP7858660.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(50878..51147)
                     /locus_tag="IVW63_000358"
     CDS             complement(50878..51147)
                     /locus_tag="IVW63_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858661.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(51617..52072)
                     /locus_tag="IVW63_000359"
     CDS             complement(51617..52072)
                     /locus_tag="IVW63_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAP7858662.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(52210..54138)
                     /locus_tag="IVW63_000360"
     CDS             complement(52210..54138)
                     /locus_tag="IVW63_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAP7858663.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(54335..55168)
                     /locus_tag="IVW63_000361"
     CDS             complement(54335..55168)
                     /locus_tag="IVW63_000361"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAP7858664.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(55360..56064)
                     /locus_tag="IVW63_000362"
     CDS             complement(55360..56064)
                     /locus_tag="IVW63_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP7858665.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(56087..56713)
                     /locus_tag="IVW63_000363"
     CDS             complement(56087..56713)
                     /locus_tag="IVW63_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP7858666.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            57039..59414
                     /locus_tag="IVW63_000364"
     CDS             57039..59414
                     /locus_tag="IVW63_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HAP7858667.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(59438..59929)
                     /locus_tag="IVW63_000365"
     CDS             complement(59438..59929)
                     /locus_tag="IVW63_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HAP7858668.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            60116..61036
                     /locus_tag="IVW63_000366"
     CDS             60116..61036
                     /locus_tag="IVW63_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP7858669.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            61190..61534
                     /locus_tag="IVW63_000367"
     CDS             61190..61534
                     /locus_tag="IVW63_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HAP7858670.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
BASE COUNT        20044 a        10786 c        13198 g        17614 t
ORIGIN      
        1 aactgacctt ccgcccctct cacaccaccg tacgtacgga cccgtatacg gcggttcaat
       61 aagttgagtg tacgaactgg tacttcaagg agatgtcctc atatccttgg cgggccagtt
      121 ctttgtctgt taatgatcga tgaagaatat gacttttgga gactgaccaa ataccttttc
      181 ttgtatttga ccattcatac gctttcgctt tatcgatccc taaacgaatc agattttttc
      241 ttttggttct tggattcttc cattgtttcc aaatatattg tctgattctt cgcttcaacc
      301 aaccgtttaa ctccctcatg aattctttca tctcaccaat tccatagtag ttgatccaac
      361 cagtcattag ttgcttgatt tcttttaaaa taagttggat acttcttcca cggtttcttt
      421 tagtgagttg tttgagcttg cttttcacac gctgttttgc ttttgcgtga gggcgaattt
      481 taataccttt ctttgttggc agaatgcaga atccaagaaa ctttcgtttc aatggacttc
      541 ctaccgcact cttttctcga tttaccgtca actttagttg ttcttcgaga aattgaatgg
      601 atttcttcat cacacgctgt cctgctcgtt tgcttctaac atagatattg cagtcatcgg
      661 cgtatcgaac aaatttatgt cctagatttt ctagcacttg atcaaattcg ttcaggtaga
      721 tgttacttaa caggggagag agattgcctc cttggggcgt tccttcttca gttgttgtga
      781 tgagtccatt ttccattaca ccactcatta agtattgacg gatcagtttt aggacttgtt
      841 tgtcctttac tttccgctca atgaaataca tcagcttatc gtgatttacg gtgtcaaagt
      901 aggctttcat atcaatgtcc accacatatc ggtaaccttg ttcataataa gattttgctt
      961 tcttcactgc gtcatgtgcg ctgcgatttg ggcgaaaccc ataactatta tctgagaatt
     1021 ctggttcaaa tagcggttgt aacacttgat tgattgcctg ttgaagcata cgatcaataa
     1081 ccgtgggaat tcctagtttt cttacaccgc cgtttggttt cggtatttct actcgcaaaa
     1141 caggctgagg tttatagttc ccttggcgta aattggatag taattcctcg cggtgctctt
     1201 tcaagtaagg aagcagttga tcgacggtca tcccatctgc accagccgcc cctttatttc
     1261 tgactacttg aagatacgct tgattgagat tattccgatc tagaattctc ccaaacagat
     1321 tttctacacc atcttgtttc ctctgttcac cgcaagaagt gctgcgcact tcatcatacc
     1381 cttcgtgttc cacactagct ctttgatgat agccaagttt tcttgttttc tgcggtcgtc
     1441 gcatcttctc acacctccta aattattcaa gattcttatt gttcagtcct tcgtaacggt
     1501 cagtgtcgtt actactatga cctcggctga cttctcatga ttcaccatca tgtcgccatg
     1561 atcgttgtgc tggtttgttt tcattcaacg cccacaacac cctcatgaga tctcccccgg
     1621 taagagtgaa aactttcctc ccatgtaact gctagattta ctgtataggt ttcgggcagt
     1681 attggacttt gtcttgtgat gaagacttat ccgacctaat tcagccttgt atctagtttc
     1741 tgttcgtcag ttcaggagtt tgcgtccgac ttccttcagc cacaacctca cgattgccgc
     1801 cttgtctttc gctaacagtt cctactgcca agcctgtagt ggactttcac caccaagttt
     1861 tcacccatgc agggcgcaca ccaaaaaaga agcagatccg ttagcggttc tgcttctttt
     1921 agtttattat attttcttat caataatagg aacctgattt taaaagcggc tacctcttta
     1981 ccgtgcctct ttacatacaa aaaatagagg aattaagcgt aaatggcttg gctattataa
     2041 ctaaaatgct ggttatggag atgttgcagc aagttttcga gaaaagcgta ttccatctct
     2101 tgtccattga ataagatctg gatacgataa tgatttttga aacgcttctg ttcatgaatc
     2161 tgactgattg aaagttcgcc tttgtgttct gtctgataaa gaaaagtcct tttacggcat
     2221 tcagcacagc gcttggttgc tcggcggatt tttcggaatg tataaaaact agtatcttta
     2281 ttgcataaat aaacgtcttt gatcgacagc aaatcattat atagacagga acgttcttca
     2341 gctgttaatt ctgataaaaa aagctgacct tgttttattg catcttccat cggcaagtgc
     2401 ctcctcgaac ccattatcca aatttttagt taattctaat ataccatcat taagtataaa
     2461 tgtaaacgct tgttgatggt ataagatttt cgtttctgat aaaacacgaa cattaaaaga
     2521 atctaatgcc ttaaatgtac atatttttgt tgatttataa aaagatgatt gctaaaattt
     2581 aaagtgaaaa aacgaacaaa aaacgatgta tttgctttta atgtaaataa aaaggagaga
     2641 cgtacatgga gaagaaagaa cttttgtatg aaggaaaagc caaaaaaata tatcttactt
     2701 ctgatgagaa cttgatttgg atagaatatt tagatcaagc aactgcgttg aatggcgcga
     2761 ggaaagacca gataagtgga aaaggagaat tgaataatca aatcacaagt gcaattttcc
     2821 gttatctgac tcaaagagga ataaaaaatc attttattga acaattgtct aaaaccgaac
     2881 aattagcaaa aaaagtacaa attatccctc tggaagtggt tatccgaaat attgcagcag
     2941 gaagtttctc aaaacgtcta ggtgttcccg aaggtaaaga attcatcaaa ccaatcattg
     3001 aattctacta taaggatgac cagttggatg atccatttat caatgaagag catatctatt
     3061 tcttacaact tgcaaagccg gaagaaatca gtgagctgaa agcccaagcg ttggctatta
     3121 atgaaatttt gaccgaatta tttgctaagg tcggtttggt tttagtagat ttcaagctag
     3181 aatttggccg gtcgaatgga caaattttgc ttgcggatga agtaacaccg gatacttgcc
     3241 gattatggga tgaacgtacg aatgaacata tggacaaaga cgtttaccgc agagatctag
     3301 gtgatttgat cccagtctat caagaagtat ataaccgtct atcggaacta actgaagaaa
     3361 aggagcgagt atgatgtatt tcgtaaaagt atatgtaacc tataaagatt cagtgttaga
     3421 tcctcaaggg gaggcagtaa aaaaagcagt ccatcgtatg ggatatgaaa caatcgaaga
     3481 tatccgaata ggaaaatact ttgagataca acttgctgat gcagaagaac caatcgatac
     3541 agtgattgaa acgatttgtg acaagctgct tgcaaatgta aatatggaaa cataccgata
     3601 tgaaatcaaa aaaatggagg aagtataaca tgaaatttgc ggtcatcgtt tttccaggtt
     3661 caaattgtga cgcagatatg ttatgggcag ttcgcgagat catgggcgct gatgccgaat
     3721 ttgtacggca tgatgagtcc tctttagaag gatttgatgg ggttttactg ccgggaggat
     3781 tctcctatgg tgactatttg agatgcggtg cgattgctcg gttttctaca atcatggaag
     3841 aagtgattcg ttttgctgaa gaagggaaac cagtattcgg tacatgcaat ggattccaga
     3901 tattgacaga agcaggactt ttgccaggtg tactgagacg aaatgagtct ttgcatttta
     3961 tttgcaaaac tgtaccattg aaagtcaacc ccaagacggc ctttacttca gagtatgaag
     4021 ccgacgaaat aatctatctt ccagttgctc atggggaagg aaattatttc tgtgacgaag
     4081 aaacacttca agaactaaaa aaaaataatc agattgcctt tacttataat gacaacatca
     4141 acggcagcgt ggaaaacatt gcagggatta cgaacaaagc agggaatgtg ttaggaatga
     4201 tgcctcatcc agaacgtgca gtagaagact tgctaggatc agaagatggg aaacggttct
     4261 ttgcttccat tttaaaaaac ttcggaaagg tgaccgtata gatgaaaaca ttgaaagaac
     4321 cgacagctga agagatcaag aaaaaaagaa tctatgccga atggggattg actgatgaag
     4381 aatatcgaat gatcgaagaa gatatcttag gaagaatgcc taattatacg gaaactggac
     4441 tgttttctgt tatgtggagc gaacattgtt cctataaaaa ttctaaaccg gttctacgca
     4501 aatttcctac tagtggacct catgtgttgc aaggccctgg agaaggcgca ggcatcgtcg
     4561 acatcggtga tggactagca gttgtcttca aagcagaaag tcacaatcat ccttcagccg
     4621 tggagcctta tgaaggagct gcgacaggag ttggcggaat catcagagat attttcagca
     4681 tgggggctcg tccaattgcg ttgctagatt cattgaggtt cggcgaatta gataatccaa
     4741 gaacgaaata tttactagaa gaagtagttg caggtatcgg cggatacggc aattgtatcg
     4801 gcataccgac tgtaggcggc gaaattgcat ttgatccttg ttatgaagga aacccattag
     4861 tcaatgcaat gtgcgtaggt ttgattgaac acaaacatat ccagaaaggg caagccgctg
     4921 gcgtcggtaa ttcgatcatg tatgtaggtg caaaaacagg tcgcgacggt atccacggag
     4981 caacttttgc ctcagaagaa tttaatcaag aagaagaaca gcaacgttct gctgtacaag
     5041 taggcgatcc ttttatggaa aagctgctgc ttgaagcgtg tttggaatta atcttgcatc
     5101 attcggattc tctaataggt atacaggata tgggagcagc aggacttgtt tcatctagtg
     5161 cggaaatggc ttcaaaagct ggctcaggac ttatattgac attagatgaa gtcccacaaa
     5221 gagaaactgg gatgacacct tatgaaatga tgttatcgga atcacaagaa cggatgttga
     5281 tttgtgttaa atcaggagag gaagaaaaaa tccaagaact atttcagaag tatgatctag
     5341 atgcagtcac tatcggtaaa gtaacagacg acgggcaata tcggctatat catcaaggag
     5401 aagaagtagc aaatctgcca gtcgatgcat tagctgaaga tgcaccagtt tatcataaag
     5461 aaatgaaaga accagctcga atcgtagaat ttcagcagtt agctccttat cagccagtta
     5521 tcgaagaacc tggacaagta ttgcttgatc tgctgcagca accgacgatt gcttcaaaac
     5581 gttcaatcta cgaaacttat gattcacaag tacaaaccaa tacagttgtc cgtccaggaa
     5641 gcgatgctgc tgtgatgagg gttagaggga cgaataaagc gttagctatg accacagact
     5701 gcaacgcgcg ctatctgtat ttggatccaa aaatcggagg acaaatagca gtggcagaag
     5761 ctgctagaaa tattattgct agcggtggta agcccttggc gatcaccgac tgcctgaact
     5821 atggttctcc tgataaacca gaagtttttt gggaattatc gacttcagct gacggaattg
     5881 ctgctgcgtg tgaaacgtta ggaactcctg ttatttcagg aaatgtctct ttatataatg
     5941 aaacggatgg tcaagcaatc tatccaacac caatgattgg tatggtcgga ttgattgagg
     6001 atcataaaca tatcactact caggaattca aaaaatcagg ggatctaatc tatatattag
     6061 gtaagacgtt tgcagatttt gatggcagtg aattacaaaa gatgcagctt ggaagaatcg
     6121 aaggtgtgat ccgaaacttt gatctatcca ttgaaaagag aaaccaagag ttagtattga
     6181 cagccatcca aaacggattg attgaaagtg ctcatgactg ttcagaaggt ggcttggcaa
     6241 ttgcactggc agaatcagct ttcaaacatc agctagggat atctgtacag tttgaattgt
     6301 cctctgctca attatttgca gaaactcaat caagatttgt gttgacagtc gcaccggaaa
     6361 ataagacacg attcgaagaa atgatgggag atgctgctgt tttagcaggt aaggtgacgg
     6421 atgaagcgat aatcgaaatt tcagcaactg acggtcagat caaaatagaa actgcagtag
     6481 caagaaagtg ctgggaggat gcaatcgtat gtcttatgaa gtgaagagtt taaatgaaga
     6541 atgcgggatc ttcggtgttt ggggtcatcc agacgccgct agtgtggcat acttcgggct
     6601 ccatagtctt cagcatcgag gacaagaagg tgcaggtatc gtgtccaatg atcgaggaaa
     6661 gcttaagggg catcgagatt tggggctgct ttctgaggta ttcaaagatc aaagaaaatt
     6721 gcagcagtta acaggagaag ctgcaatcgg acatgtacgt tatgcaacag caggcaatgg
     6781 aagtgtggac aatattcagc cttttctatt caaatttcat gatcagtcga tcggcttagc
     6841 gcataatggt aacttgatca atgctcgttc ccttagaaaa gagttagagg aaaatggggc
     6901 gatcttccat tctaactccg atacggagat attgatgcat ttgatccgac gaagtgaaga
     6961 aacagatttt ttaaataaat taaaaagtgc tttgaatgaa gtcaaaggtg gctttgccta
     7021 tttattaatg acagaaacgg caatgattgc cgctttggac ccaaatggtt ttcgtccatt
     7081 agcaatcgga caaatgaaaa acggagcata cgtgattgcc tcggaaactt gtgcattaga
     7141 agttattggg gcacgtttta taagagatgt ccagcctggt gagatagtga tcatcaatga
     7201 cgaaggaatc cagattgatt gctttacgaa ggacacgcag ctttctattt gttcgatgga
     7261 atatatctat tttgccagac cagattcaaa catcgcaggg atcaatgtgc atactgcacg
     7321 gaaaaatatg ggacggaatt tagcgaaaga atcgccagta aaagcagata tggtcgttgg
     7381 cgtacctaat tcttctttgt cagccgcaag cggttatgcg gaagctagtg gaatccctta
     7441 tgaaatcgga ttagtaaaaa atcaatacat tgcccgaaca tttatccagc caacgcctga
     7501 gctaagagag caaggtgttc gaatgaaatt atctgctgta cgaggagtag tggaaggtaa
     7561 aaaggtgatt atggtcgatg attcaattgt tcggggtacg acaagcagac ggatcgtcca
     7621 tcttttgaaa gaagcagggg caaaagaagt ccatgtgagg attgcttctc ctcctttgaa
     7681 atatccatgt ttttacggga ttgatattca aacgcgtaaa gaactcattg cggcaaatca
     7741 cacgattgat gaaatcaaag aatgtatcgg tgcagattct ttaggttttt taagtgaaga
     7801 gggtctgatc gaatcgatcg gtctggaaaa agatgctccg tattcaggat tgtgtatggc
     7861 ttatttcaac ggagattatc cgacgccgtt atatgactat gaagaaaaat atcaggaatc
     7921 actaaaagaa aaagtatcgt tcttttaaaa gcagaccaag aagggagtat atgaattcaa
     7981 tggcaaatgc atacgcaaaa gctggcgtag atgtcgaagc tggatatgaa gtagtagaac
     8041 ggatcaagaa gcatgtcaaa aaaacggaac gtttaggtat gatgggcgct ataggaggat
     8101 tcggcggttg ttttgattta tcggtctttc aattaaaaga gccagtcctt gtctcgggga
     8161 ccgatggcgt ggggacgaaa ttagcagtag caatcgaagc agacaaacac gatacaatcg
     8221 ggatcgactg cgtagcgatg tgtgtcaatg atatcttagc acaaggcgca gagccgttat
     8281 atttcttaga ctacttagca acggggaaaa atgatccgtt acgtttggaa aatgtagtaa
     8341 aaggtgtagc agatggatgt gttcaaggaa atatggcgct gattggcgga gaaacagctg
     8401 aaatgcctgg tatgtactca ggtaatgatt atgatctagc cggatttgct gtagggatag
     8461 ctgaaaaatc tcaattattg acaggagaaa cgatcaaccc aggagatgtg ttgcttggaa
     8521 tagcatctag cgggattcat tcaaatgggt actctcttgt tcgcaaaatt ttctttgagc
     8581 agcagcagtt ttctttatca tcaaaactgc cagaattgaa aaaaacactt ggcgaagaat
     8641 tgcttgagcc aacgaaaatc tatgtttctt ccttgcttcc gctgatcaaa gaaaagaaaa
     8701 taaaaggagc tgcacatatc actggtggag ggtttgtaga aaatatcccg cgaatgttac
     8761 cagaatctat ggctgcacaa atcaaacttg gctcatggcc gattcttcca atattcggct
     8821 gtttacaaaa atatggtgaa attcctgaga tggagatgta tgaaatcttc aatatgggca
     8881 tcggtatggt cctggcagtc caagaatcga aagtaaaaga aatagtacac gaaattgagc
     8941 aagctggcga aaaagtttat gaaatcggga aagtgatcgc caaagaaaaa catcgtgtgg
     9001 tgtttatagg agaagaacga tgagaatcgc tgtttttgct tctggaaacg gaagcaactt
     9061 tcaagcgcta gccgattatc tatcgaaaaa aggattggaa tcttcgattg actggttgtt
     9121 ttgtgatcag cctgaagcat atgttttgaa acgtgcaact gcgttgagtg taccggcaga
     9181 ttgtttttca cctaaagaat ttgattcaaa aaaagagtat gaagaagcaa ttttgcataa
     9241 attgaaagaa aaaaagatcg atttgatcgt attagctgga tatatgcgaa tcattggacc
     9301 ggtattgctg aaaaattatg ataaaagaat catcaatatc catccgtctc ttttacctgc
     9361 cttccctggt ttgcatggca tacgtgatgc ctttgaagct ggagtaaaag aaacgggtgt
     9421 cacaattcat tatatcgacc aaggtgtaga tactggacca atcatccggc aggaaaaagt
     9481 gagaattgaa caggaggaca cgttcgattc tttagaagaa aaaatccata gagtagagca
     9541 tcgaatctat ccagaagtga ttagtgaaat tattgaaaat ggaggctatc tgaaatgaca
     9601 agagcattga tcagtgtatc agataaaact gggattgtag cattcgccca aggtttgatt
     9661 gaacaaggag tagaaatcat ttcaacagga ggaacaaagc atgcgttgga taaagctggg
     9721 atcaaaacgc tttcgatcga agaagtgaca gggtttcctg aaatgatgga tggccgtgtc
     9781 aaaacacttc atcctaaaat ccatggtggt cttttaggaa gacgcgatct ccctagccat
     9841 atggaggcaa tggaaacgga aaatatccaa ccaatcgact ttgtttgtgt caatttatat
     9901 cctttcaaag aaacgattat gaaaccagat gtcgaaatag cagaagctat tgaaaacatt
     9961 gatatcggtg gtcctagtat gctccgtagt gcagcaaaaa accatgaatt tgtcacctct
    10021 gttgttgatc catctgacta tgaagaagta ctttcagaat tacgtcagta tgggcatact
    10081 tcactttctt tcagacaaaa actagcggca aaagtctttc gtcatactgc ggcatatgat
    10141 gcactgatcg ctcaatactt aacggattgg gtggaagaaa aagaaccgga aaaattgaca
    10201 cttacgtatg aacgaaaaca aacgcttcgt tacggtgaaa atagccatca agccgctgcc
    10261 ttttatcagt ccgctcttct ggaaaaatat tcgatcgcag cagcaaaaca actccatggg
    10321 aaagaacttt cttataataa tatccgagat gcagatgctg cgctacggat catgaaggaa
    10381 tatgacgagc caacggtagt cgccttgaaa cacatgaatc cttgtggtat tgggacagca
    10441 tctacgattt tagaagcgtg ggaagcagcg tatgaagcag atcctgtttc aatctttggt
    10501 gggatcatcg ttttgaatcg agaagtagat ctgccaacag cagaacagat gcataagctg
    10561 tttctagaaa tcatcattgc cccttcttat acacaagaag ctttggaatt actgcaaaaa
    10621 aagaaaaaca tccgattact gacagtagac tttgcgcagg aagaaaatca aaatcgagaa
    10681 gaaacggtct cagtcttagg tggacttctt gtacaagatc aagatctggc aatagaaaat
    10741 gaagaagagt ggaaagtcgt gacaaaacgt aagccgactc cagcagaagc aaaagcatta
    10801 gcgtttgctt ggagagctgt caaacatgtg aaatctaatg cgatcgtact ggcaaacgaa
    10861 cgtcagacag taggaatcgg agccgggcag atgaatcgag tcggttcagt aaaaattgcg
    10921 attgaacaag cgcaagagaa aatggaaggt gcagttttag ctagcgatgc ttattttcca
    10981 atggatgatt cggttgaata tgcagccaaa catggtataa aagcaatcat tcagccagga
    11041 ggaagcatca aagaccaaga ttctattgat atggcgaata aatacgatct agcaatggtc
    11101 tttactgatg ttcggcattt tagacattag agaggagtcg gataaatgaa cattttggtg
    11161 atcggtgcag gtggtcgtga acatgcaata agtaaaaaac ttttagccag tccgaaggtg
    11221 gatacggtgt attgtgcgcc aggaaatccg gggatgacaa aagatggtat caattgtgtc
    11281 gctatcagtg agcgagatca ttcagcgtta atccattttg ttaagaaaga ggctattgat
    11341 tggagtatcg ttggtcctga agttcctttg ttaaatggga tcgtcgatga ttttatggcg
    11401 gaaggattga aaatcttcgg tccgacaaaa gcagcagctc tgatcgaagg ttcgaaaagt
    11461 tttgctaaac aattaatgga tacttatcaa atcccgacag ctaaatccag aagttttgaa
    11521 tgttacgaaa aagcagcagc gtatatcaaa gaaaatggtg cgccaatcgt agtgaaagcg
    11581 gacggcttag cagctgggaa aggtgtagtc gtggctacca cagtgaagga agcgctggat
    11641 gcggcagaac aaatgttgaa ccagcatcga tttggggata gtagcaaaaa aatcgtcgta
    11701 gaagagtttt tggcaggaga agaattctcc cttttggcgt ttgtccgtaa taccaaggtg
    11761 tatccgatgg tcatttcgca agatcataag cgggcatttg ataacgataa agggccaaat
    11821 acaggcggaa tgggtgctta ttcaccagta ccgcaaattt caaaaaagat gattgaaaaa
    11881 gctgtggaag aagttttaaa accagcggct ttgggaatga aagaactagg acgctctttc
    11941 acgggtgttt tatatgcggg tttgattgct acgaaggaag gaccaaaagt gatcgaattc
    12001 aatgcgcgtt tcggtgatcc tgaaacgcaa gtcgttcttt ctcggttgaa gagtgacttt
    12061 gcgcaagtaa tcgatgattt attagagaat cgtacagtag agttaaagtg gcagcaagaa
    12121 ggatacaatg taggcgttgt ggttgcagct gccggttacc ccgaagaata tgagacagga
    12181 atggttctac cagattttct ggaagaagag ctttctgttt actatgctgg agtttcctca
    12241 aataacggca aactagttgg agcaggagga cgtctttatt tagtagaagc atacggtgag
    12301 acgatcaaag aagcacagaa aaaaatttac accgcgttaa tggataaaac gacagatgga
    12361 acattttatc gtacagatat tggagaaaaa gctgccaata gcgaactgat cgtgaagtaa
    12421 atcagctgct tccatttata aaaaatacaa caaacataat cggaagcgcc gattttagtg
    12481 aagccttttc ataaagagtg tggtacactt ttgttgtgta tataaataag gaggagttca
    12541 gatgaaaaaa attcaattag gtacttctga tcagaaagca gctgcagtga tcttaggctg
    12601 tatgcgtatc aacaatgcgg aagatccagt aaaagtgatt gagacagctt atgaaaacgg
    12661 cattgatttt tttgaccatg cagatattta tggaaacggt gaatgtgaag aaatctttgc
    12721 agatgctcta gcaaaaacat caatcaaacg agaagatctt tttattcaaa caaaatgtgg
    12781 aatcgttcca ggtgtgatgt ttgatttttc taaaaaacat atcattgaat ctgtagaaaa
    12841 aagtttgacc cgtctgaaaa tggattatgt ggatgcttta cttcttcatc gtccagatac
    12901 attggtagaa ccagaggaag tagctgaagc gtttgatgaa ttggaacggt caggaaaagt
    12961 tcgttatttt ggcgtcagca atcaaaaacc aatgcaaatc gaattgctga aaaaatatgt
    13021 tcgtcaacca ttagtagcta atcagctgca atttggcttg aaacatactg gaatgatcga
    13081 tcaagggatt catgtcaata tgacagatga agcaagtatc gatcatgacg gtagtgtact
    13141 tgattattcc cgattgcatg atatgacgat ccaagcatgg tcaccatacc agtatggatt
    13201 ttttgaaggt gtatttatcg ggaacgaaaa attccctgaa ttaaaccaaa cattagaaga
    13261 actagcagct aaatatcaaa cgacaccaac tggcttggct tctgcttgga ttttacgcca
    13321 tccagccaat atgcaagtga tcgccggtac gatgaacgta gggcgaatca aggaaatcgc
    13381 tcaagcttca gaaattaata tgtctcggga agattggtac gaattgtacc gtgctgctgg
    13441 aaacatttta ccttaaagat tgtcataagc aggtcaaaag ggctataaat taaaaagaca
    13501 gaataacttg aaagctgttt tcagcttcga gatattctgt ctttttttat tgcaaatgga
    13561 aagagtatca ttgtacggat ttcgtttatt agttattttt gtttttaagg aaaagctgtg
    13621 tccgatattc ttttggagaa atcccttgtt ttttcttaaa taaataactg aaatagttag
    13681 ggtcattata accaatttca aaagcaatat ctgaaatacg atagtctgat tgctgcaata
    13741 atttttttgc taattcgatt ctttgttctg tcagataatc gatgaatgtt tggttaaacg
    13801 attgagaaaa aatcgtactg aaatgagagg gacttaatgc aacttgttga gcgacccaag
    13861 ttaaggacat atctggatcg gtaaaatttt ctttgataaa atccaatgca tggttcaaaa
    13921 ttggctgata tttgttcctt gaaggctgtg agggcagagc agttaagaaa gaaatgaaca
    13981 tataaactgt cgaacggtaa agcgagtcgt cggcgctgat tgctaagcgt tgactggtgg
    14041 atgtgcaatg aaccatttct tgcgggattt tcttttcttt caggcagaca tgctggagta
    14101 gcttagtcaa gacaaataaa cgatataatc gtgttcgagt tggtgtgcct tgtggtttcg
    14161 tcaagtgttc gatgtactta gatacttcgt ttttcgataa tgaagacaaa tcaagtgaga
    14221 ggtcaaagta aaagacagaa tcaactggaa gtttcgcttc ttgaatcaaa tcctcatagc
    14281 tgataatttg ttctttaagg gaactggcgg tttcaagtat catctgcgtg atctcaaaag
    14341 atgcaggtaa ttcgctgatt ctttctgcga caggaccaat ggcgacagaa aaattatttt
    14401 tttgtccctt ttctaattca tggaccaacg tttgggctac ctgataactg gtctcgatca
    14461 cattttcttc aagagaatca actattaaaa atttgatgaa tcgagaggaa acagcagaga
    14521 agatcacttg ttgattctcc ctaaataaaa acttcaaata atcactgaga tgagcgtaat
    14581 cttcaaagtc tgtactgact tggtttgctg ctaataatac ggtcattttt ttccctgcta
    14641 aagagcgatt gaaagattca gcaagtttca atgtttcact gatcgtaagt gagcctttga
    14701 acaaaccgtt caagaaatga ttttttttca attcgaaaac aagatcagaa gaagtgtgcg
    14761 tttctttttg ctgcaaatct aaagcagtta ctgctttttc tattgcttgt ttcaattcgc
    14821 tacttttaat cggtttaagc agataatcat ctgcctgtac ctggattgct cctttcatat
    14881 aatcgaaatc gtcgaatcca ctaataaata tgagacgagt ccaaggaagt agtttccttg
    14941 cttcttttga aaaagtcaac ccgtccatga aaggcatttg gatatcagtc agaatgatgt
    15001 cgggctgtaa gtcgataatt gaagacagtg ccatctcacc atctccagct tcgccgacat
    15061 aagtgattgg ataataagaa ccaaggacag ttatttgttc ccgcaagtta ttgcgaatga
    15121 ggtattcgtc ttcgatgata aaaactttat acatgtttgt ttcctccaat tgttttggga
    15181 gatagaggga tcatcagtgt gacagttgtt ccttctcggt atttgctgtc aatcgtgata
    15241 ggtttttgat catttccgta ataaagaagg agacgcttgt ttacgttgta aagtccgtag
    15301 ccgatactga aatctgaatc gatccctttg gctaactctt tacgtatttc tgccagtttt
    15361 tctgcaggga tgccaatccc gttgtctata actttgaatt ggatcatctc atcaattttg
    15421 catgtggtaa tacgaataaa tcctttgtga cggacgtact tcgttccatg gtatacagca
    15481 ttttcaatca atggctgcaa gatcattttt aaaatagaaa caggaaaaag tgtttctggt
    15541 atatcgatct tatagtcaag catatggccg tatcttattt ttaagatgac tagataatca
    15601 ttgatatggc taatttcttt ttcaagagga atccagtctt gtcctttgct taaagacgta
    15661 cgaaaaaagc cggaaagtgc atgggtcata gtcagagctt cttcaaagca gtcttgttcg
    15721 atcaaagaaa taatggcatc caaactgtta taaataaaat ggggagtaat ctgagcttgc
    15781 aatacacgaa cttcactttg tgctaaatgg tattgtttca aagcgttctc ccgtaaagac
    15841 tggtttagat cttccgccat tttattcatg ctagcggtaa gtgtttgtaa ttccagtgtt
    15901 tccggcaggg ttaaacgaaa gccaaggttc cctgaagaaa gttgttctga catctcgatc
    15961 agctgattga tcggttcttg gacctttctc tctaaaaagc gacgattctt tttcgcatag
    16021 aaaaaaatgg tactaagaac tccaagttcc actattgtta atagaatgag cgagcggaca
    16081 agtgtcgtat tttttttgct tgctaagtcg atctccacac gaacaaaatc ttgtaagata
    16141 tctgacagca gttgagtgac agaatctacc tgattgatga tctcttcatt ggtatccata
    16201 aaatcttttg ccaagatatt attgatcagc tcgttttgat aatcttccag tgtatcgatc
    16261 gtacgtagcg atacatctaa cgtactaatt tctttaagtg tatttgtatt atttttgatc
    16321 tctcgaatat cattcctaag ttcttctagg atattttcct cattgaactc atctacggtt
    16381 acttggccag aaatcaagtc ccacatactt tccaaaactt tttgatcaac cttcaaagca
    16441 attgcatctg ctttttggat atttgcgatc gtctgttgat aaatcaaaag ctgttgcgaa
    16501 tataacagta tgctcagtag caaagggata acagcaaata gaagcatggc tttgtttgct
    16561 tgggcaaaaa tctgttttat gcttaaattt tttgtcatga tacttctcca gtcaataatt
    16621 tctggttggg atgttagcta tattctgctg ggaaaagaca gtctcggaaa taaaaatatc
    16681 tttaggtaat gtttttcctg tttgaatatt tccaaaataa cgagtaacgg tattggctac
    16741 ataccagccg acatcaggtt tacactcgac tacacaattg acgattcctg agcgtagctt
    16801 ctcgatcata tcttcttgtc catcaatagt tacaatgatc aaatcttctc caggtttgat
    16861 tgatgtttct tttatcgcag ctaaagcacc gtgagtcatt tcatcactat ggctgtataa
    16921 tacatcgatt tcggataaat catttgtttc taaatatcgt ttcatctggt cttttccttt
    16981 catccgaata aaatcaccga caattcggtg aacaatagtc atcggaggtt tatggtcgat
    17041 ggttccatct ttttttaggg ttggtttacg attgattgat tccaaaaatc cttcggagcg
    17101 tagcttggtc ggtgtggagt tctctgaacc agcaagttct aggattctga tttcctgttt
    17161 ctttgaattt gtgaagtgat tgctgacaaa taaacccgcc cgatttcctt ctgctttgaa
    17221 actggggcca atgtgggtga cgaaaagctc gggatcattc gtttgaatat gtctgtcgac
    17281 aagtatgaca gggatccctg ctcgctttgc ttcttttaat acagagtccc acccggattc
    17341 ttgcaaagga gtaaaaatga tcatatccac tttataggca atgaacgtcc gtatatcttg
    17401 gatttgccgt tcctgattca tgtagccatt tcggtagaga acttggtaat cttctttttc
    17461 aagcgcagtg ataattgatt cagtatgctt tttccgccag ctactctccg ttcctgattg
    17521 cgaaaaacca acgactagtg ggtcaggtgc ttcctttgta ttaggtgtac accccatcat
    17581 ttggtaagcg attacaacaa gggctaaaaa aaataaaaca cgtttcactt taaatcactc
    17641 catctggatt tgttagtact atcttatcag ataaaaggga aaatcaaagt caaaaggaat
    17701 caatcgaaaa aaatccaaga aacttaaaaa aatccaagac aaaaaaagta cacctaaaaa
    17761 atttaaagta aatcccataa aaaaatcaat gttaacgctt tctttattag ctatactcgg
    17821 tgtatcaatt gaaatggggg ataaaaaatg aaaaacaaat ttagaaagat tgttgggact
    17881 atcgctattt tgaccgcaag cattctatta agtgcgtgtg gcaattcagg atctgcagat
    17941 gatagtacgg ggtatgtagg aatcgctatg ccgaccaaat cagcagaaag atggatcgct
    18001 gatgggaaca acatggtctc ggaattagaa aaactgggtt ataaaacaga tcttcaatat
    18061 ggagaagata aagtagaaaa tcaagtagca caaatagaaa atatgattac aaaaggggta
    18121 gatacacttg tgattgcttc tatcgatggt tcggctttaa ctgatgtgtt agctaaagca
    18181 aaagaagcag atatcaaggt gatcgcctat gatcgtttac tgatgaattc agaaaatgtc
    18241 gattattacg cgacttttga taattttgga gtaggtgtat cgcaagcagc ttatattgaa
    18301 gagcacttag gattgaaaga aggaaaagga ccattcacga ttgaattatt tggtggctcg
    18361 cctgacgaca acaacgcact aatcaattac aacggagtga tgtctgtttt acaaccatat
    18421 atggacaacg gtcagttggt cgtgccatct ggacagacga gtttcagtca aatcgctacg
    18481 cttcgctggg atggttctac ggcgcaagca aggatggata atctgttaag cgcaaattat
    18541 actgaccaaa cattggatgc tgttttgtcg ccatatgatc caataagttt aggaatcatt
    18601 tcgtcattaa aaggcgtggg gtatgggagt gaaagtaaac ctttacctgt gattactgga
    18661 caagatgcga cagttgctgg cgttaaatcg atcattgccg gggaacaaac acaaacgatc
    18721 tttaaagaca cacgtatctt agcaaaaaat acgattgaaa tgatcaaagc aatcagtgat
    18781 ggagaagagg ttccggtcaa tgatactgaa acttatgata atggggtgaa aactgtccct
    18841 acgtatttag caaatacagt atctgtcgat aaagataatt atcaagcaga gctgatcgac
    18901 accgattatt ataaagaatc cgatctgaaa aattaagagg aaccaaacaa ggaactaaag
    18961 agatctaagt cagagagagg ataagaatta tggcggattg tattttaaaa atggcagata
    19021 tcaccaaaaa attttctgga atccgagcgt tagattgcgt gaatctgatg attgaacgtg
    19081 gggaaatcca tgcattgtgc ggagaaaacg gagcgggaaa atcaacattg atgaatgtct
    19141 tgagcggctt gtatccatat ggctcctatg acggggaaat cttttatgat ggaaagctgt
    19201 gtcaatttaa agatttgaaa gatagtgaag aaaaaggcat cgtcatcatt catcaagaat
    19261 tagcactaag tccttatctt tcaataaaag agaatatttt tctcggaaat gaacaagcag
    19321 aaagaggcgt gattgattgg gaactgacag aaaagaaaac atatgaactg ctgaataaag
    19381 tcggtttgtc tatcgacccg aatcttctag tatcccagat tggcgtaggg caacagcaac
    19441 tagttgaaat agctaaagca ttatcaaaat ccgtccgtct gttgattttg gatgagccta
    19501 ccgctgcatt gaatgaagaa gaaagcgcga atttgctgag attgatccga gagttgaaag
    19561 agcaaggtgt aacctccatc attatttcac ataagctgaa tgaaatcgtg gatatcgcag
    19621 atcgaatcac cattttacgg gatggacaga cgattgagac actagaaaat gaaatgatca
    19681 gcgaagagca tattattcgc ggaatggtgg gcagagattt agttgatcgt tatcctgaaa
    19741 gaaaaccgga tattggagaa gtttatttta aagtagaaga ctggacggtc tatcaccctc
    19801 ttgatcacga gcgaatcata aacgaccaca tcaacttgca tttgaaaaaa ggagagattg
    19861 taggaatagc tggactgatg ggagcgggca gaactgaatt cgctatgagt ctatttggac
    19921 attcttatgg aagcaagata tccggacgta tattaaagga aggggcagag atatcagtta
    19981 agaccgttcc ttcagccatt gcaaacggac tcgcttatgt ctcggaggac cgaaaatctt
    20041 taggactgaa tctgctgatg gatattcggg aaaacgtgac gctgagcagt ttggataaaa
    20101 taagtcaaaa aggagtatta gataaagaaa aagaagtaac tgaggcagaa aatttccgga
    20161 aaaagatgcg tataaaaaca aactccatcc atcaaattgt cagtagtctt agtggtggga
    20221 atcaacaaaa agtcgtttta tccaagtggc tgatgacaca acccgatatt ctttttttgg
    20281 atgagccaac ccgtgggata gatgttgggg caaaatatga gatctacacg attatcgaag
    20341 aaatggcagc aaatggcaaa gctgtctgtc ttatctcttc tgaacttcct gaaatattag
    20401 ggatgtgtga tcgaatctat acgatgaacg aaggacgtat tacaggagaa gtctcgcgag
    20461 aagatgcaga tcaggaagtc ttgatgaaat taatgacgaa agaagaggtg ggttaagttg
    20521 gaacaggcaa aaaatcttac ggataaaaaa gagaaaaaac taaatttgaa aagtagagca
    20581 gctgatcttt ttggtcgcta cagcatggtg atcattttag cgggactact tattgcgttt
    20641 caattgatga cggatggtat tttctggcgt ccattgaata taactaacct tgttctgcaa
    20701 aatagccata tattagtact agctgcaggg atgttattag ttgtgctctt aggtcatgtg
    20761 gatttgtcgg tagggtcagt gatggcgttt gttggtgcaa ttgcgggcat gatgatggtc
    20821 aatcgccaaa tgaacccgtg gatgacagtt atcgcatgtc ttgcagtagg cgggctgatc
    20881 ggcgcatggc aaggtttttg ggtagcttat gcagggatac cggcgtttat cgtgacttta
    20941 gcaggattgc tgatgtttcg tggactgaca caagttgttc taggaggcca atctctagca
    21001 ccttttccag ctgttttcca aaaaatgtct acgggttatt taccagactt aagcgaagga
    21061 agcagccttc acttcttgac attgatttta ggaatgatca tcacgatcgt gttagttgtt
    21121 ggtcaatggc gaacaagaaa tcgtcggaaa aatcatttat ttgaagtgga atctccaaca
    21181 gctttcttgg taaaggcggt atttacagca gtcgttgtac taggaataac ttatatcttt
    21241 gcctcttatc aagggtatcc gattattttg atcattcttg gtttgatcgt tgcagcatat
    21301 gggtttttga caaataaaac agtagcaggt cgacagattt atgcgacggg cggaaatcga
    21361 aaagcggctg aactatcagg gatcaaaaca aagcgaatca cgttctgggt attcgtcaac
    21421 atgggagtca tggcagcttt agctggatta gttttagctg ctcgattgaa tgcggcaaca
    21481 cctcaagcag gtacatcgat ggaactggat gcaatggcgg cagtatattt tggtggtgct
    21541 tcgacttccg gcggcattgg aacaatcatg ggtgcgattg tcggtggctt ggtcatgggt
    21601 gtattgaaca atggcatgtc gattttaggc gtcggggtag actggcagca ggcaatcaaa
    21661 ggattgatct tgcttttagc cgttgtgcta gacttgtata ataagaaaaa acgaacaacg
    21721 taggagaacg ccggttattc agaaaaaaga ctgtgacaag acatttgtca cagtcttttt
    21781 ttcgctaaaa gcgaacattc attgtttcgt ttgtatagac taaaaataat atatgttttt
    21841 ttaccattcg tataaattct ctttttgctc ttgatttttt tgcttaattg agttaaatta
    21901 catagggcgc taaaaaaagc cttgattaaa ttaataatgt tcgtgttttg ctggatgtga
    21961 acatcaggag gataatgtaa tgaaagtatt tgattacgaa gatattcaat taattcctaa
    22021 taaatgtatc gtaaatagcc gttctgaatg tgatacaacg gtcacattag gtaaacatac
    22081 attcaaaatg ccagtagtgc ctgccaacat gcagacgatt attgatgaaa caatcgcaga
    22141 attcttagcg gaaaatggtt atttctatat catgcatcgg tttgatgaag cagctcgaat
    22201 tccgtttatc aaaaaaatga aaaagcgtgg attgattacc tcgatcagtg ttggcgtcaa
    22261 gaaagaggaa tattccttta tagagaagtt ggcagaagaa tcgctaaatc ctgattatat
    22321 cactatcgac atcgcgcatg gacatgctaa ctcagttatt gatatgattc agcatattaa
    22381 aaaatatttg cctgaaactt ttgtgattgc cggtaatgtt ggtacaccgg aagccgtccg
    22441 tgaattggaa aatgcgggcg cagatgcaac aaaagtcggg attggtccag gaaaagtatg
    22501 tattacaaaa atcaagacag gctttgggac tggaggctgg caactggcag ctcttagatg
    22561 gtgtgcgaaa gcagctcgca agccgatcat cgctgacggt gggatcagaa cacatggcga
    22621 tattgcaaaa tctgtccgtt ttggtgcgac aatggtcatg attggttcat tgtttgccgg
    22681 tcacgaggaa tctcctggcg aaacaaaagt cgaaaatgga atcgtgtata aagaatactt
    22741 tggttctgct tcagaattcc aaaaaggcga aaaacgaaat gttgaaggaa agaaaatctg
    22801 gatccaacac aaaggatctt tgaaagatac actagtggaa atgcaacaag accttcaatc
    22861 atctatttct tatgctggag gaagagatct ggaagccatt cgaaaagttg actatgtcat
    22921 cgtgaaaaat tcgattttta atggagacac aatctaaaaa ataaataaaa tattaggatg
    22981 ttgtgaaaaa gttgtcctgc attaagtaat aagaacagcc aaacaaaaat agttctttat
    23041 atgttttgtt tggctggaat tattatcgca gatacaagct tttgaacatc attattcaga
    23101 ataagggact gtgataagat ttttgtcaca gtcccttatg ttttgcaaaa aaagtttttc
    23161 ttttttctcg taaattcggt aaaatcaaaa gaaaaaatag acaatagaaa agagaagctt
    23221 atgtgggaaa aagtagagaa aaaacaagga ccgatttatc gtcaaattat ggaacagatt
    23281 atgagagaaa tcgaaaacgg aaggatcaat cctggaagtc aacttgaatc agaacgaaaa
    23341 ctagggcaac tttttggtgt gaatcgttcc accgttgtcc atgcattgga agagcttagg
    23401 gagcttgggg tactaacgag caaacgtggc agcggatggt ttgttaatca gactgaatgg
    23461 gggaaattcg ctgttccaag aatcgattgg cggcaaatga tctctcctcg ttatgagcag
    23521 acggactggt atgagcaaaa aataagagaa gcaaagcaga tccaaaaaac atcgtttctt
    23581 gatttatacg ctagcgagat gccagatgag cttttgccga attttgagtt tccttcttat
    23641 tctcttgaag aaatcttagc ggaagaaaaa gaaatggatc ttttaggcta tactccgtta
    23701 cgtaacaaaa tcaaacggta tttggaaagt aaatttgaat tggcattttc ccccaaccag
    23761 cttcttgtga ctggtggcgg tcagcaagca atctttttga ttttacaaac gattctttca
    23821 gctggagagg ggatagctgt agagtcacct tctttttttt accgattacc tcttttcaaa
    23881 gcttcaggaa cgcgtttatt tgggataccg atggatgaag aagggatcga cttagaaaaa
    23941 ctgaaagaat cgatccataa aaataaattg aaagcagtgc ttatcaaccc gaattttcaa
    24001 aaccctacag gaaaagtgat gagtcaaaaa cgacgagaaa agctagtaga attgtgtcga
    24061 cagtatcggc ttccaattat tgaagacgat gtatttacgg atctttcatt tctaaaccaa
    24121 gaagaagtcc ttcctatacg aacgattgat ccggataatg tgttatacgt cggttcgtta
    24181 tctagggttt taggaaaaac aacgaaaatc ggttgggtga taggacctga gacttttatc
    24241 tcgcaactag ctcaagcgca agaaatgatg gagttttcga tgaatatcct tacacaaatc
    24301 acagtggcta atgtatttaa tgaagcaatt gatttgaaaa tgcaagatgt aagaaaaaag
    24361 ttgaaagaaa aaagccgact gataagcgct tggggagatt cacaatcgtt tttcaagctt
    24421 cattcaattt taggtggtta ctatgcctgg attacttggg atgggaaaaa actagacccc
    24481 gaactagcag aaaaagtagt agatatgggt cttggaattg caccaagtct actttttggg
    24541 caagatataa atggaatcag aatcaattac agtaggctgg atgaaaacca aataccgttg
    24601 ttttattcaa agatgaaaat tctagaaaag tggttaacag aataatttca caaagtaaat
    24661 agattaaaga atataacagc ttggatttaa atttcaagct gtttcttttt tttcggaaaa
    24721 agaatacgat ataaagaaac taagaaaaaa ccattatttg tacgtccgtt cacgatgtgt
    24781 aaataaaata aatgtttgca acaaaactgt ataacaccaa cgtttttaaa tagaaacaga
    24841 tggttgtaag tttgattaga aaatagaaaa aatgcagatg aaatataaaa cgctttcctt
    24901 attgtgattt tattcactaa tgctgttaat atgcggattg gcataatttc ctttcatcgt
    24961 gaaaatttgt gcttttagct tgtatttctc ataaatccat gataatttat taatgaagac
    25021 ggttaaatag tgatacagtt ttattcactg tttcaatcgc agaatgaaga gattttctta
    25081 tagatgagag aggaatgtgt gacaaatggc aaacaaaaaa gcaccgatcg acttccaagc
    25141 actgctagat gaagtcaatg cagatttccc agtatatcaa gcacttgatc aagatggaaa
    25201 cgtagttaac aaagatttag tacctgattt atccgatgat gaactcgttg aattaatgac
    25261 tcatatggta tggtctcgtg tattagacca acgttcaaca gcgctgaacc gccaaggacg
    25321 cctaggcttt tttgcaccaa ctgctggaca agaggcaagt cagctggcta gtgcttacgc
    25381 atttgataaa gaagatgttc ttcttccagg ttatcgggat gtacctcaac tagtaaaaca
    25441 tggtttacct ttatctcaag cttttttatg gtctcgagga catgctgcag gtaattctta
    25501 tccggaagaa ttgaaagctc taccaccaca aattatcatc ggtgcacaat atgtacaagc
    25561 agccggtgtt gcattaggtt tgaagaaacg aaacaagaaa aatgtcgtct tcacttatac
    25621 tggtgatggc ggttcatcac aaggtgattt ttacgaagca atcaatttcg ctggcgctta
    25681 ccatgcaaat gccgtatttt atatccaaaa caacgggtat gcgatctcta cacctcgtga
    25741 aaaacaaact gcagcaaaaa cacttgcaca aaaagctgtc gcagctggga ttcctggtat
    25801 tcaagtcgat ggaatggatc cgcttgcagt atatactgta tctaaaatgg cacgggaatg
    25861 ggcgatcagt ggaaatggac cagtcctaat cgaaacactg acttatcgtt atggaccaca
    25921 tacactatct ggtgacgatc caacccgcta ccgtacaaaa gacacagatg acgattggca
    25981 gaaaaaagat ccattgatcc gcttccgtaa atatttgacg gaaaaaggac tttggtctga
    26041 agaaaaagaa gaacaagtca tcgaagcaac taaagaagaa atcaaagcag ctattgctga
    26101 agccgacaaa gtaccaaaac aaaaggtttc agatttcttg aaaaacatgt tcgaagtatc
    26161 tccacaatca atcaaagaac aaattgcaat ttatgaagcg aaggagtcga aataatcatg
    26221 gcacaaaaaa caatgatcca agcaatcaca gatgccttag cacttgaact agaaaatgac
    26281 gagaatgtcg ttgtttttgg tgaagatgtt gggaaaaacg gaggagtttt ccgggcaact
    26341 gaaggattgc aggaaaagtt cggagaagac cgagtattcg atactccttt agctgaatct
    26401 ggaatcgcag gattgagttt cggtcttgcg ttagaaggat ttcgtccagt tcctgaaatc
    26461 caattctttg gttttatttt cgaagcaatg gacgaagtag tagctcaaat ggctcgtaca
    26521 agatatcgaa tgagcggcac tagaaatcta cccatcacaa ttcgttcgcc atttggtggc
    26581 ggtgttcata caccagaatt gcattcggat aatttagaag gtttgatcgc tcagtctcct
    26641 ggtattcgag tagtgattcc ttccaaccct tatgatgcaa aaggactatt gatttcttct
    26701 attagaagta acgatccggt tgttttccta gaacacatga aactatatcg ctcattccga
    26761 gaagaagtgc cggatgaagc ttacgaagtt cctttggata aagcagcagt tactcgtgag
    26821 ggaacagatg tatctattat cacatacgga gcaatggtgc gtgaagcaat caaagcagca
    26881 gacaatcttg caaaagaaaa tatatctgtt gaaatcattg atcttcgtac agttgcgcca
    26941 ttagatgtag aaacgatcat tcaatccgtg gaaaaaactg gtcgcgtagt tgttgtccaa
    27001 gaagcacaac gacaagcggg cgttgccgcg caagtagttt ctgagatctc agaacgcgct
    27061 atcctttcat tagaagcccc aatcggacga gtttctgcac ctgatacagt cttcccattt
    27121 ggacaagcag aaaatgtctg gttgccaaat gcaaaagata tcgaagacaa agtaaaagaa
    27181 atcgcggaat tttaagaaaa gaagggacga aacaaagtca tggcttatca atttaaattg
    27241 ccggatatcg gtgaaggaat cgcagaaggt gaaatcgtca aatggttcgt caaaccagga
    27301 gatacgatca atgaagatga tacattacta gaagttcaaa atgacaaatc agtagaagaa
    27361 atcccgtcac ctgttacagg aacggttaaa aatgtgattg ttccagaagg taccgtagca
    27421 aatgttgggg atgtattagt agaaatcgat gcaccaggac acgaagacaa tgaaggggac
    27481 agtggtgtag ccgcagaatc ccaaactcca gctaaaccgg ctgctgaacc cactgttgat
    27541 acagaatcag ctggatcgtc aagcgaagga gtcttccaat ttaagttacc ggatatcggt
    27601 gaaggaatcg cagaaggtga aatcgtcaaa tggttcgtca aaccaggaga tacgatcaat
    27661 gaagatgata cattactaga agttcaaaat gacaaatcag tagaagaaat tccgtcacct
    27721 gtcacaggga cagttaaaaa cgtgattgtt ccagaaggca ctgtagcaaa tgttggggat
    27781 gtattagtag aaatcgatgc tcctggacac aatagtgcac cgtcaactag tgcgccatca
    27841 gctgaagcac caaaagaaaa agtggaaaca tcaggttcag caagtgtcgt tgaagctgcc
    27901 gatccaaata aacgtgtatt ggctatgcca tctgttcgtc aatttgcccg tgaaaaagat
    27961 gtagatatct cacaagtaac tgcaactgga aaaggtggca gagtaacaaa agaggacatc
    28021 gaaaacttct tggcaggtgg tccaagcagt gcaccagcga aatcagaagc gccagaagcg
    28081 gcagcaccga aagaagcagc tcctgcagca gaaagcaaac cagctgcacc agcaaaacca
    28141 ttcaagtcca acttaggaga cttggaagaa cgtgtagcaa tgacgccaac acgtaaagct
    28201 atcgctaaag caatggtcaa cagtaagcat acagctccac acgtgacatt gcatgatgaa
    28261 gtagaagtgt ctaaactatg ggataatcgg aaacgattta aagaagttgc tgctgcaaat
    28321 ggtacgaaac ttactttctt gccatatgtc gtgaaagctt taacagcgac tgttaagaaa
    28381 tacccagtat tgaatgcatc tatcgacgat gcaaaccaag aaatcgttta taaacattac
    28441 tacaatatcg gtattgcaac tgatacggat cacggactat atgtaccaaa tgtgaaagat
    28501 gcagaccgca aaggaatgtt tgctattgca gacgaaatca atgagaaagc aaaattagct
    28561 catgacggca aactatctgc agaagatatg cgcaatggaa caattacgat cagcaatatc
    28621 ggatctgtag gtggcggttg gtttacacca gtcatcaact atccagaagt agctatttta
    28681 ggtgtaggaa cgattgcaca acaaccaatc gtaaatgctg aaggcgaaat cgttgtcggt
    28741 cgtgtgatga aactgtcatt aagtttcgat caccgtatcg tagatggagc aactgcgcaa
    28801 caagcaatga ataatatcaa acgtctttta gctgatccag agctattaat gatggaagga
    28861 tgataaacaa atggtagttg gagattttgc tgtagaatta gatacagttg taattggtgc
    28921 gggacctggt ggctatgtag ctgccatccg cgctgctgaa atgggacaaa aagtagcaat
    28981 cattgaaaga gagtatattg gcggtgtttg tttgaatgtc ggctgtattc cttcaaaagc
    29041 actgatagct gcaggacacc attatcaaga gtcactagat tctgaaatgt ttggagtaac
    29101 tagtgaaaac gtcaaactag attttgcaaa aacacaagaa tggaaagaaa acaaagttgt
    29161 ccatacgttg acttctggtg ttggtttcct attaaaaaaa cataaggttg aaacaatcga
    29221 aggagaagcg ttcttcgtag atgatcacac actacgcgtc attcatccag attcagctca
    29281 aacttattcg ttcaataacg caatcatcgc aacaggttcc cgtccaatcg agattccagg
    29341 atttaaattc ggaggacgtg tgttagattc tactggcgga ttagcattga aagaagtacc
    29401 taagaaattt gtgatcatcg gtggcggtgt gattggtgcc gaattgggcg gagcgtacgc
    29461 aaacttagga gcagaagtaa cgattcttga aggctcacca caaattttac caacttacga
    29521 aaaagatcta gtaaaattag tagaagatga tttcaagaaa aaaggcgtaa cagtcgtaac
    29581 gaatgcaatg gcgaaagaag cagtcgataa cggtgacagc gtgacagtga aatatgcagt
    29641 ggacgggaaa gaagaatccg ttactgctga ttatgtgatg gtcactgtag gtcgtcgtcc
    29701 gaatacagat gatatgggct tagaacaagc gggtgtcgaa gtaggagaac gaggattgat
    29761 cacggtggat aaacaaggac gtacgaacgt acctaacatc tatgccatcg gtgatatcgt
    29821 tccaggggcg gcattagcac acaaagccag ttatgaagca aaaatcgctg ctgaagcaat
    29881 ctctggcaaa aaagtagctg tagattataa agcaatgccg gcagtagcct tcactgatcc
    29941 tgaattggct tctgtaggta tgacgatcaa agaagcaaaa gatgctggta tcgaagcaaa
    30001 agcatataaa ttcccatttt cagggaacgg tcgggcatta tcgcttggta aaacagaagg
    30061 attcatccgt ctagttacga cgatcgaaga taacgtgctt attggcgcgc aaatcggtgg
    30121 agtcggcgca agtgatatgg tctctgaatt agctttagca atcgaatcag gaatgaatgc
    30181 tgaagatatc gccttgacga ttcatcctca tccatctctt ggcgaaatcg tcatggatgc
    30241 ttcggaatta gcattaggtt taccaatcca tatttgattt gaataataca ggcgaaacgc
    30301 aactgaaaaa tcagttgcgt tttgtttttt agaattatca ataatattat tatgtaaact
    30361 taaaaatatg acaacttctt ggtttattac cacttcctat gctacactga agaggaatat
    30421 gaaataggag agttgaagat gcaagaatat cagtatccac ttgatttaga ttggacaaca
    30481 gacgaaatgg tcattgtaat gaagatgtgg gaagatctgg aacgtgcgaa tgaaaaaggg
    30541 ataaacaatg aagctttttt gaagacttat cagcagttta aaactgttgt caaatccatt
    30601 ggtgaggaaa aacgattggg acgggaattt gaaaaagctt ccggttattc tttatatcgt
    30661 acagtgcagc aagcaaaaaa aaatccaaac aaaactttga gaatgaacgg gtgagataaa
    30721 tggaacagat gattgatcat atcaagtcct ggcttgaaga agctggtgag aaaatcaaat
    30781 cttctcaaca aacattaaca atctcgcaaa aatcaaatcg aacggatcta gtaacaaatg
    30841 tcgatcgaaa catccagaat tttctaatcg aaaaaatcca ttcctttgat ccagaggcga
    30901 aaatattggc agaagaagaa gggtgtaatc aattatcgga tctcgatgga agagtcttta
    30961 tcatcgatcc tattgatggc accttgaatt ttgtgattga aggggaaaat ttttgtatta
    31021 tgctcgctgt ttatgaatcc ggcgttggaa agcttggttt catttatgac gtgatgagaa
    31081 atgaactttt ttggggtgga aaaggaatag gcgtgtataa aaatgatgag ccattgccta
    31141 gaccagcaaa taaatcctta tcggaaggct tacttggtgt gaatagttat cttttcggtc
    31201 ataataaata tggaatccga gaaattgcgg aaagcagcat ggggacacgt atgtacggat
    31261 gcgctggtct tgaactagtg gcaatcttga aaggaaacca cattgcttat atttcaaacc
    31321 ttagcccttg ggattatgca gcgggaaatg tcttattgga agagtttggt atggtaacaa
    31381 gcggtctttt tggtactcct ttgacatttg aaaaaaggga atactattta gcagggactt
    31441 cttgtgcata tgcagaaatc gcagaccttt tgaaaaaaga aggctgaaaa aaaggtagaa
    31501 atcattcaca aaaatgataa aaacgagcaa aagattaatt ttctcgaaaa aatgaaaaca
    31561 ttttactata tttcatgaaa aaagtctgct ataattagca gtcgagtaaa atttgccctg
    31621 tcataaagaa ccaataaaaa aggagttagt tacattgaat tatagaaacg atatccgtaa
    31681 cgtcgcaatt attgcccacg ttgaccacgg aaaaacaaca ttagttgatg aactattaaa
    31741 acaatcagat acattagacg cacatacgca attgcaagaa cgtgcgatgg actcaaatgc
    31801 gctagaaaaa gaacgtggta tcacgatttt agccaaaaac acagctgtag actataaagg
    31861 tattcgcgta aacatcatgg atactccagg acacgcggac ttcggtggcg aagtagaacg
    31921 gatcatgaaa atggttgacg gcgttgtgtt ggtcgtagat gcgtatgaag gaacaatgcc
    31981 tcaaacacgt tttgtattga aaaaagcact ggaacaacat atcacaccaa tcgttgtcgt
    32041 aaacaagatt gacaaacctt ctgctcgtcc tgagcatgtc gtagatgaag ttcttgaact
    32101 attcatcgaa ttaggagcag atgatgatca gttagacttt cctgtgattt atgcatctgc
    32161 actaaatggt acgtcaagct tgtcagatga tccagcagat caagaaccaa ccatggcacc
    32221 tatttttgat acaattattg aaaaaatccc tgctcctgtc gataacagcg acgaaccatt
    32281 acaattccaa gtttcattac ttgactacaa cgattatgta ggtcgtatcg gaatcggacg
    32341 tgtatttaga ggaacaatca aagtaggaga ccaagtagca ttaattaaat tagacggaac
    32401 agttaagaaa ttccgtgtaa cgaaattatt tggtttcttt ggactaaaac gtctagagat
    32461 tcaagaagca aaagctggag acttgattgc tgtctcaggt atggaagata tctttgtcgg
    32521 tgaaacagtt actcctgtgg atcatcaaga tgcgttacct atccttcaca ttgacgaacc
    32581 aacattgcaa atgactttct tagttaataa ttcaccattt gccggtcgag aaggtaaatt
    32641 cgtaaccgct cgtaagattg aagaacgttt gatggcagaa cttcaaacag atgtatcctt
    32701 acgagttgaa ccaacaaact ctccagatgc atggacagtt tctggtcgtg gagaattgca
    32761 tttgtctatc ttgattgaaa acatgcgccg tgagggatac gaattgcaag tatctcgtcc
    32821 agaagttatt gaaaaagaaa tcgacggtgt aaaatgcgaa ccgtttgaac gcgtgcaaat
    32881 cgatacacca gaagaatata tgggtagtgt tatcgagtcc ttgagcttac gtaaaggtga
    32941 aatgcaagat atggtccata caggaaacgg acaaatccgt ttgacattct taacacctgc
    33001 ccgcggtttg attggttatt caactgaatt cctttcaatg acacgtggtt acggaatcat
    33061 gaaccatact tttgaccaat atctgccaat gcttcctggt caaattggcg gacgtcacca
    33121 aggggcgctt gtttcgatcg atacaggaaa agcaacgact tattctatca tgagtatcga
    33181 agaacgcggt acagtcttcg tagaaccagg tacagaagta tatgaaggaa tgattatcgg
    33241 ggaaaacagc cgtgataatg atttgactgt caacatcacg aaagcaaaac aaatgacaaa
    33301 cgtacggtct gctactaaag accaaacatc tgtcatcaaa aaaccaaaac aattgacgtt
    33361 ggaagaatct ttggaattct tgaatgatga tgaatattgc gaagtaacac cagaaagcat
    33421 tcgcttgaga aaacaaattt tagagaaaaa tgctcgtgaa aaagcatcta aaaagaaaaa
    33481 ataatctgta aaaggatgaa gagagaaacc agcttgttat aaaaaatagc tggtttcttt
    33541 ttttgtccaa ctcttttctg tggagaagtc atctttgtca atggacataa attcagaaaa
    33601 tacgccgaaa gacgtttaaa agacttttaa aaaacttatt tctagagagt ttttgtttca
    33661 taataagata atgtttcacg aaaggagatc aacttgtcct tcgaagaaaa tcgaagtaaa
    33721 atggcaagag aaaggagcgg gaagatgaac gacttattaa aacaatactt tggctatgat
    33781 gagtttagac ctggtcaaaa agaaattatc cagaaagtca ttgatcagga aaatgtatta
    33841 ggaatcatgc ctaccggaag tgggaaatca atctgttacc agcttccagc tttactatta
    33901 gatgggctta ctgtggttgt gtccccttta atctctttga tgaaggatca ggtggacgcg
    33961 gcgaatcaat taggtatacc cgccactttt atcaatagct cgttagatgg ttacgaaaca
    34021 gctagacgct tccaagaaat cgatagacag cagtaccgtt tactttatat cgctcctgaa
    34081 cgttttatca tgccggattt tatccaagca atgaagcgat ggaacgtccg tatgatcgct
    34141 attgacgagg cacattgtat ctctcagtgg gggcatgatt tccgcccaag ttatttacag
    34201 atggcgaacc agctagatca actgccaaat cgtcctgtaa ttgttgcttt gacagctaca
    34261 gcgactgtgc aagtagctgc tgacataaaa agacttttaa aaattccaga aaacaaccat
    34321 attcagactg gttttgaacg agaaaatcta cgatttcaag taattaaaga tcaaaaaaaa
    34381 gaacaatatc taatcgaata tttaaagatc aacaaaaatc aatctggtat catttatgca
    34441 gcaacgagaa aagaagtaga ccgtctctat catttgctta aaaaattcga tttttccgtg
    34501 ggtagatatc atggtggtct aaatgagaat gagcgaacag aaatgcaaga agccttttta
    34561 tacgatcgct tgcagctgat tgtagcgaca aatgcatttg gtatgggtat aaataaaagc
    34621 aatgtccgtt ttgttatcca ttatcaaatt cctggctctc tagaagcata ctatcaggaa
    34681 gctggtcggg cgggaagaga tggtctttcc agtgaagcca tcctgctttt ctctcctcaa
    34741 gatatccaag tccaaaagtt ttttatccag cagtcccaaa gagaagaagg gcaaaagcaa
    34801 aaagaatatg aaaaattaaa agcgatgaca gaatacgtgt atattgagtc ctgtcttcag
    34861 caatacatcc taaactattt tggcgagaca agcagtccgt gcaaccgttg tggtaactgt
    34921 ttagatgaca gagaaatagt agaagtaacg acagaagcac agatggttct ttcttgctta
    34981 aaacgtatgg gtgagaacta tggtaaacaa atgctgatga aagtcttagc aggatcgaaa
    35041 gaacaaaagc tgcaagcttt aggttttgga catttatcta cctatggact gatgaaaaac
    35101 caatcgcaaa aagaaacgat gcagttaatt gaatatttga tatcgaatgg ctatcttctg
    35161 accatcaatg gtgagtatcc tgttttgaaa gtaacagaaa gagggataca agtattgaaa
    35221 ggacaagaat ctgtttatcg aaaggaaccc aagaaagtcc agcagctatc ggatgaagaa
    35281 accgatacac tatttgaagt gctgcgggaa ctgcgaacgg atctagcatc agaagcaggc
    35341 gttcccccgt atgtcgtatt ttcagattcc acattgaaag aaatgagccg aatacgtcca
    35401 tcaagcagat tggagatgct tcagataaaa ggagttggcc aaagcaagct tgataaatat
    35461 ggcgaagcct ttttatctcg gataaaaaat gcggactcta acgttctgga taagtagaaa
    35521 gaacgaatac gtaaaaatga ataaaaacaa ctggttaaat ctgttttttt tgctccttat
    35581 gaaaatcaaa tatgttataa ttaaggaatt agaatgggag gtaagcacag atggattctt
    35641 tgtcgaaaaa acttgcgatc caagtattaa atgatgaagc agaacggatc aaacgattaa
    35701 tccgaaatca aaacaacagt ctctgtatct cacaatgcaa agccttcgaa gaagtggtag
    35761 atacacagat gtacggcttt tcccggcaag tcggttttgc tgtccgtata ggagtaatcg
    35821 gaaagaacga gggccagctg atgttaagtg agctagaacg agaattgaat cagttatata
    35881 gtgaggttta ccaagaaatt tatgataaaa aagaagttgg caaggaggaa tagacttgcc
    35941 taagaaagtg aaaaaaaggc atctattaga ctatagcatc ttgattccct atttaatttt
    36001 atgtgtattg ggattgatca tggtatatag ttctacgtcg tatctattat tagaaaacgg
    36061 acaaaatccg tccgcatcag tcattaacca gagtattttt tgggtgctta gcttgattgc
    36121 tatcgcacta ctttataaaa tgaaaacaga tgttttgaaa aaccagcgtt tgatcatggc
    36181 agccatcgca gttttgacga ttttgctgct gattgttgtg ttttttggta aggagatcaa
    36241 tggggcgaaa ggttggctgc aaattgcagg attctcgatc caacctgccg aatacctaaa
    36301 aatcatttct atctggtacc tgtctctgac tttatctaaa agacaaaaca gtgtacaaaa
    36361 agattttctt gggactgtga aacgtccact tgcaatggtt atcggactta ctgcattagt
    36421 cgctattctt cccgattttg gtaatgcggc agttatcttt ttgattattt tggttctgct
    36481 tttagccagc ggagtcaatt atgtgtatac tttgattgta ggagtaggag gcttttgtct
    36541 aagtactttt acgatctggc tgatcaatat cacaaacgga aagatcttac ccggacgttt
    36601 acagtatatc tataatcgat ttgctattta ccaaaatcct ttctcagacg aattaaataa
    36661 agggcatcaa ctagtcaacg gctactatgc catgttcaac ggaggactat ttggcagggg
    36721 attaggtaac agtatccaga aaaaaggatt tttacaagaa gcacaaaccg attttattta
    36781 tgcaatcgta gtggaagaac tgggagtgat tatggggatt ttgatattag cgttgctatt
    36841 ctttatgatt gtgcgcattg tccttgtagg tatccgttca aaagatccgt tcaattcgct
    36901 tttgtgcatt gggatcggcg caatgttttt gatccaagta tttgtcaatc ttggaggaat
    36961 tactggcgtt attcctttga cagggatcac gttcccattt ttaagtcaag gaggctccag
    37021 tttgctgatg ctttcgattt gtgtcggctt tgtcctcaac atcagtgcgg atgaaaaacg
    37081 caagagctta ggtttataat aaaaaaagat gtaggagtgg ttcgatgaaa aaagttttag
    37141 ttgctaacag gggtgaaatc gctgtacgtg tatttcgtgc ttgtacagaa ttaggaatta
    37201 aaactgttgg aatctatgca gaagaagatg aatattccgt acaccgtttc aaagcggatg
    37261 aagcatattt agtaggacaa ggaaaaaaac cgattgatgc gtatctagat attgaaggga
    37321 tcatttctat cgcgaaagaa tgcggagctg acgctattca tccgggttac ggtcttttgt
    37381 cggaaaactt gaattttgcg caacggtgcg aagaagaagg catcattttt gttggaccca
    37441 aactgcatca tttagatatt tttggagata aaatcaaagc aaaagctgca gctatcgaag
    37501 cggggattgc ttcgattcca ggcacagatg gaccaatcgc ttctatagac gatgccttgg
    37561 agtttgcgaa acaatacggt tatccgatta tgatcaaggc agctctaggc ggcggcggac
    37621 gcggcatgcg tgtagctcac gatgaaaaga gtgcaagaga gggctacgaa cgtgcgaaaa
    37681 gcgaagcaaa agcagccttt ggtagtgatg aagtgtatgt tgaaaaatac atcgctaatc
    37741 ctaagcatat cgaagtacag attctcgggg atacgcatgg aaacgtcatc catctttttg
    37801 aaagagattg ttctgttcag cgccgtcacc aaaaagtagt agaagtagcg ccttgtgtct
    37861 ctatgaatga acagcaacgt caaaaaatct gccaggcagc tgtccaattg atgaaatatg
    37921 tcgggtatgt caacgcaggt acagtagaat ttcttgttga aggagatgat ttttacttta
    37981 tcgaagtcaa ccctcgcgtc caagtggaac atacgatcac agaaatgatt acagatattg
    38041 atatcgtaac aacgcaactg ttgattgctc aaggtttgga tctgcataaa gaaatcggat
    38101 tgcctcagca agaaggaatt aaattaaatg gttcagccat tcaatgccga atcactacag
    38161 aagacccgtt gaataacttt ttaccagaca cagggaaaat cgatacgtat cgttcacctg
    38221 gtggttttgg cgtacgtctg gatgtcggaa atgcttacgc gggctatgta gtgacaccgt
    38281 attttgattc attgctagta aaagtatgta cgcatggtgc tacctttgaa acagccattc
    38341 agaaaatgga acgttgcttg aaagaattta gaatccgtgg agtgaaaaca aacattccat
    38401 ttatgctcaa tgtcatcaca catcctgaat tccaatcagg aaatgcaaaa acaaccttca
    38461 ttgatagtac agcaacatta tttgaatttc ctcgactacg agaccgcgga aacaaaacga
    38521 tgaaatatat cggtgaaatt actgtgaatg gttttccagg tatcgaaagt ggcgaaaaac
    38581 cattttatga agaaccacgt atgcctaaag atctaatcac aagaactgat tacgtaacgg
    38641 ctaagaatgt attagatgcg aagggtgccg atgctttggt cgaatggatc aaaggacagg
    38701 aaaatttgtt gttgacggat acgacattta gagacgccca tcaaagtctg ctagcaactc
    38761 gtgttcggac aaaggatttc aagcagattg cacgtttgac tggagaaggt cttcctgaac
    38821 tcttttcaag tgagatgtgg gggggagcaa catttgatgt ggcttaccgc tttttgaatg
    38881 aagatccttg gcaacggttg agaaaaattc gttctttaat gcctaatacg ttgctgcaaa
    38941 tgcttttcag aggttcaaat gccgttgggt attctaatta tcctgacaat gtattggtgg
    39001 aatttgtcaa agaagcagca gcgcaaggaa tcgatgtatt tcgaatcttt gatagtttga
    39061 actggactcc acaaatggaa aaaagtatcc aagctgtacg ggatactggt aaaatcgcag
    39121 aggcagctat ttgctatact ggcgatatca acgatccaag tcgggcaaaa tacaatgttc
    39181 agtattataa agacatggca aaggaactag aacaactggg tgcgcatatc attgcaatca
    39241 aagatatggc tgggctgctt aaaccgcagg cagcttatcg tttgattagt gaattgaaag
    39301 aaacgacaga tctgccaatc catctgcata ctcatgatac cagcgggaat ggaatcatca
    39361 cttattctgc tgcttcaaaa gcaggagtag acatcgttga cgtggcaatg agtgcaatga
    39421 gtgggaatac tagtcagcct agcatgagca gcttgtatta tgcactggtc aatggtccac
    39481 ggctgccaga aatcacgatt gaaaatgcac agaaattaaa ccattattgg gaagatgtgc
    39541 gcatgtatta caaaccgttt gaaaacggct tgaatgctcc tgaaacagaa gtatatatgc
    39601 atgaaatgcc aggaggacag tattcgaatc tacagcaaca ggcaaaagct gtcggattag
    39661 gtcatcgctg ggatgaaatc aaacaaatgt atcatactgt caacttgatg tttggcgata
    39721 tcgttaaagt aactccatca tctaaagtag ttggagatat ggcactattt atggtccaaa
    39781 atgatcttac agaagaagat atttatgaaa aaggcgaaac actaagtttc cctgaatctg
    39841 ttgtgacttt cttccaagga gaactagggc aacccgttgg cggatttcct aaaaaattgc
    39901 aaaagattat tcttaaaggc agacctgcat tgaatgaacg tccaggtctt ttggctgaat
    39961 cagtcgactt caacgaagta aaaaaagaat tggcagaaaa aattggctat gaaccaaaac
    40021 aagacgaagt attaagctat ttgatgtatc cgcaagtctt tttggactat caaaaagcat
    40081 ataatcaatt tggcgatgtt acattactgg acacaccaac atttttccaa ggtatacgtt
    40141 tgggtgaaac aatcaatgta caaatcgaac gcggaaaaac gcttatcatt cgtttagatg
    40201 aaatcggaga acccgatatc gaagggaatc gcgtactgtt cttcaatttg aatggacaaa
    40261 gacgtgaaat cactatcaaa gataattcga tcatcagtac ggtccaaacc cgattgaaag
    40321 ctgaaccgac aaaccgagaa caaattggag caacgatgtc tggttctgtt ttggatgtat
    40381 tagtgaaaaa aggcgataac gttaaaaaag gtgatacgtt gatgattact gaagcgatga
    40441 aaatggaaac ggccatcgaa gcacgttttg acggagaagt cgcacatgta tatgtgtctt
    40501 caggagacac tatttcgtct ggtgaccttt tgattgaagt gactgagaaa taataagcga
    40561 aaggtgggga aacatgaaaa gactgggttt gttttggctg attctgctat tagttattgt
    40621 ggcattctac atggaaccag tcttgtttcc gccaaaactt gaagtgaagg aaaactctga
    40681 tcaacaaata tcaaaccaaa tgacaacgtg gaaataccag gagcttaaag caactggttt
    40741 ttctacttat atcggaaaac cgatcgatca gctggaaaag gattttggcc aagcctatga
    40801 tcgattaact agcggatttg gttttgaaac aagatattat gaaaataaag ctagtcatct
    40861 cacatttgaa gcgaacatcc aagacagcag agtcacaact gttaaagtac tgcaaacagg
    40921 gcctgctgat atcgcgccgt tttatttagg gatgacgatg caagatctta cgaaaatcac
    40981 tactatctat actaatttca cttttgagta ccatgataca gaagttggaa tcgaactaat
    41041 ggaagaggat atgaattatc gtccgctaat tgcttttgat aacgacactt ttgctatttt
    41101 attttttgat caaacaacaa acggcctatt ttcagttgtg tatttagata aagatagtct
    41161 tttgaaacta ttgccatatc aagtgtttgg tgaaggcctt ccacattatc aagcagataa
    41221 atcggctgat tgggaatcaa tcaatcgcgt taaagaacga aaaagtacga ctttattaaa
    41281 tatgcttaga agagaagacg aacttcccat atacaatcaa acacttgcct ttcaaaacca
    41341 cagtcagctg ctactacatg attttttgac aaggcctgag gaaatattgt cagaggaacg
    41401 tatggctgat tggcaaaaat cgctaggcag tgctcaaacg acagtgaaat tctcactgac
    41461 gaatgatgaa ttggagaagt taatcagtaa acaaaaatta gaaaatacta gtgggctatt
    41521 tattcatccg gcgattgacg ctactttttc gtttttatat tggtacagcg atccttacaa
    41581 ccatgaccgt ttcatggacc cgggaacgga ttctgtaggc attgcttttt ctaaagaaaa
    41641 tatgttagtc ttattgcaag aagaaaacgg agaaagtagt gatagcagtg atcgttaacg
    41701 aagagctgtt tcaactggag gatcaatgcc tccaagtcgc tgaaatgata aaaaagagta
    41761 aaacgatggc ttcttatctt gaacataaac agtcaatgga agaatctgca aaagtttgcc
    41821 agttgaaaga agcgttcttg tctaagaaag aagcatttga aaatgtagcg gcatatggtg
    41881 agtatgcacc tgattatcgt gaaaaaaaac gagctgttcg aaaagcaaaa agacagcttg
    41941 atatggatga gcatgttgca gctttccgat atagtgaaac acagctgcaa agtctgttgg
    42001 atcaaattgt ccaagtactt gccgaagaag tttctaatga aatcaaagta gatgcaggta
    42061 gcccgttttt tgaaacgaaa aaacactttg gatgcggagg taattgtcat gcaattagac
    42121 aatagtgaat ttgaaataac aaaacgacgc gggctgatcg tatgggtcta cagcttaaaa
    42181 caattaaaga atctgaaaaa gttcggcttg ttgcattatg tctcaagaag aatgaaatat
    42241 gtcgtgcttt acttaaatga agagacattg gaagaaacag aagaacgaat ccgtaaatta
    42301 cattttgttc gaaacgtaga acgttcttac cgaccggata tcgaaatgaa ttttgccgaa
    42361 aaaataggaa acaaaacagt attaaaagac gaaggtttcg aaattgaaga gctaaataca
    42421 gaaatccgat tagctgaaca tctttaaaaa tctcttatga gcagttttta aataaaaaat
    42481 aacttggata acgatcgatt tttgatcatt gtccaagtat ttttttggta tactagtacc
    42541 agtaccattt ctaaggagtg agtagatgcg gataatatca ggaaattatg gcgggcgccg
    42601 tttaaaaagt ttagcagggg cgaacaccag accaactaca gataaagtaa aagaatccat
    42661 attcaatatg attggaccat attttgatgg agagacagta ttggatctgt ttgcaggaag
    42721 cggtggttta gctatcgaag cagtatctag aggctgcagt catgcggtat gcgtagacaa
    42781 aaattaccaa gcgctaaaaa tcatcaaaga aaacatcgaa attacgaaag aaccagagaa
    42841 atttaccaca ataaaacttg atgcggacaa agcaatcgaa cggctagcag cggagaaaca
    42901 acaattcgac tacttgtttc ttgatccgcc atatgcaaaa caaaaaataa tcgatcaaat
    42961 ccataaaatg gaagaactgg gacttttttc taaaaccgca gttatcgtat gcgaaacgga
    43021 taaaacagtc gaattgccag aaactgtggc tggattccat caaataagaa aacagattta
    43081 tggcataacg gccgtaacta tctatagaaa agagggaaat caatgaaacg tgcattattc
    43141 ccaggaagtt ttgatccttt tacaaaaggt cacttagata cggtggaacg tgcggctaaa
    43201 ttattcgatg aggtagtaat tggtgttttt atcaatactt caaagaaaag tttgtttccc
    43261 ccagaagaaa gaatgacatt gatcacaaaa gctgtttctc atcttcctaa tgtaaaagtc
    43321 atgcatcaag aaaatcaatt gacggtagaa acagcaaaag agattggtgc agatgcgttg
    43381 atcagaggca tacgaagtat caaagacttt gaatatgaac gagagattgc tcagatgaat
    43441 catcatctat atgatgaatt ggaaactgtc ttcttattag caaaaccaga atatagtcac
    43501 gtgagttcca gtattttaaa agaagtactg cactttggcg gagatgtgag cagctactta
    43561 ccgccagtga tcaacgaagc tttagctgga aagcgtgaat caaatgaaag ctaaacaatg
    43621 gttgaaaaca gtactgatta tcatatttgg aatgttgatc attggatttg tagtagttcc
    43681 cttgccgtat tatgtagaat caccgggagc cacgatcgat ctgaaagaac taattacggt
    43741 caatgataag gaagataaag gttctgggtc tttctctctt acctctgttg gtatcaggca
    43801 agctacaggt ttcttagctt taaaagctaa aatgacccct tttgaagaat tgatcagtga
    43861 agaagaattg actggtgggg cgacaaatga agaatataat caaatgcaac agtattatat
    43921 ggattcttcc caaaatgcag caatcgaaca agcgttaaaa cttgcagaca agccttataa
    43981 aatggaattc aaaggcgtat atgtcatgag tgtagagaaa acatcgaatt tctttggcaa
    44041 gctttcagtt ggagatacag taacaaaagt agacgggaaa agctttcaaa gtacagaagc
    44101 atttatggat tatgtaaaaa gccaaaaagt tggacaaaca atcgaaatca gttatttgca
    44161 taatggtgaa gaaaaaacag cttctggtga tctgatcgag ttaccaacag ataaaaaggc
    44221 aggaataggt atcacgctta ctgaccatac cgagatcgaa tcagatacag atgttcgtat
    44281 taattctggc tctatcggtg ggccatcagc gggattgatg ttcactttag aaatctatga
    44341 acaagtcact ggtaaaaact tgcgacatgg taagcaaatt gcaggaactg gaacgatcaa
    44401 cagtgaagga gaagttggcc gaatcggagg aatcgataaa aaagtggcaa gtgcggataa
    44461 agctggcgta gagattttct ttgcaccaga tgatacgatt tcagacgatg ttaagaaaga
    44521 atatcctgaa ataaaaacca actacgaaga agcaaaagct gccgctaaaa aattgaattc
    44581 ctcaatgaaa atcgtaccag taaaaacagt acaagaagcg cttgactatc tagagaaaat
    44641 gaaatgaaac taaataatta aagaggggtt gtgacacgag ttctgtcaca acccctcttt
    44701 ttcgtcaaaa atcttcacga taaaaataaa aacaaaagaa aaaattgacg taattagatg
    44761 ttgaagggac gattttgcca gagctcactg tttcttcaat tttaaatgaa aggagtaatg
    44821 aatgattttt actggtcatt ctttgaaaaa agaacaatga tagaaaaaat cagcaagaaa
    44881 atactagctt cacccaaatt gatcatttgg atgtctatga tagttcttat cttttgtatc
    44941 gcaagtggtt ttttattatc aaatttgcta ttttatagag aaacagaaga gactgctgca
    45001 aaagaaatac tttcttcgtt tagttccagt ggagaagatc catcagctga aggaaacgat
    45061 gtagaagagg atgctcgtcc aaaggtcatg tacaccgata tcaaaggaag tgtgaaggag
    45121 cctggtatct attccttttc ttcagaagaa cgggtctatg atgtactaaa gcgtgcaggt
    45181 ggattattag aagaagcgga tagcgatcga atcaactttt ctgcgaagat agaagatcag
    45241 caagtcctat atatccctgc tgtaggtgaa gagctgccag aacatcttga tcagttggca
    45301 tcctcggaag gaaaacagcc tacagcagat tccgagcctc ccaaaataaa tatcaataca
    45361 gccactccat cagaacttca gcagattcct gggatcggat cagtcaaagc gcaagaaatc
    45421 attcgattta gagaagaaaa cggatccttc cagaaagtgg aagacctgca ggagatttct
    45481 ggtatcggtg aaaagacagt tgaaaaacta aaaaacttcg ttacaattaa atagaatgat
    45541 tcaaaatcga ctggcacgag caataaatgg acgctaatgg atactaagaa taatccaatt
    45601 ctaagagctt ggcaggacga ggaggtagta tttttggata ggaaatagct tgattgttcg
    45661 caaagaaaca ttaaaaaaac caatgctgaa tgtctatctc caaaataaaa tatctgggat
    45721 tcatattatg aatacggctg tcagcggcaa taacagtcaa gctctacgag aacgctttgc
    45781 caaagatgta cttagctata cagcagataa agtatttatt ctcattggga cgaatgatct
    45841 agcagagcat aaacaacttt ctaaagaaac gtaccaaaaa atctgcagtg gatgatagtt
    45901 cagctgaaaa aagactatag ttctgatcat gctttcttta tcacgccacc agcagtcgat
    45961 gagacaaaac aaaaatatcg gaataacaag ttgatcaaag aatatatctc tgttctcaca
    46021 gaagtagcaa aacgccatga ttgtgaagta tcgattttta tacggaattt cttgaacaaa
    46081 tggattcgaa gaatttttat aatgggctaa tggatgacgg acttcatttc ggcagtgaag
    46141 ggtaggatct tttgtcagac aggatgattc gttatattta aagaatattt tgtttaagca
    46201 atgagtactt tttaatcaac ttgaaaaaac ggaggaatat aaaacatgtt agaaaaatct
    46261 tcaaaagcat gcgatacgaa taaagaaaaa gttactgata agtcacataa tgaacgcatt
    46321 ccttgggacc agtactttat ggctcaggca gtactgttat ctttacgtag tacgtgtaca
    46381 cgtttagaag taggagcgac actcgttcga gaaaaaagga tcattgctgg cggctataat
    46441 ggagcagtca gtggagatgt ccactgcata gatgaagggt gttacgtcgt ggatggacac
    46501 tgcttgcgaa cgatccatgc agagatgaat gcactcctac agtgtgcaaa acttggtatc
    46561 ccgacggaag gttcagaaat ctatgtcaca cattttccat gtttggcctg tacaaaggct
    46621 ttgttgcaag ctggtgtgaa agggatcaat tatctccatg actatcgaaa tgatccttat
    46681 gcccaagcgt tgatcgaaca attaggtgta tctgtacacc aagttgcttt agactcacag
    46741 catttttcaa aacttcaaaa tgaattaaca ggaaaacatg tctagcgttt tagaaaggca
    46801 tgttcgaaat cggttgattt ttccggcaat tacgtcgatg attatctgtt tgttgtatta
    46861 cactgacaat tggggttatc gtttgcttct tgccggaatt tttttatggt tttcgctaaa
    46921 agaaggacgt tttatcgcgt acttgtgtat tttgtgtagc ataacggtat ccatttctta
    46981 taggctacaa gagtattcat ttttagagga aaaaacaaca tctgcgcaaa ttactgtatt
    47041 tacagatacg attcgtgcaa atggtaattt tttgacaatg gaaggaaggt tatcagagaa
    47101 taaacaaaag ctccagcttt cttatcaagt aaacacagaa gcagaattga aaacatggct
    47161 taacttccga ggaaagggaa tagaattgac tgctgaaggc gagttcatct ctccagcaaa
    47221 aaagcggaat ctttataatt ttgaccaaga agcttacttc aggaaccata gaatttctgg
    47281 acggttccaa attcaaaaga ttgaacagat caccatgcaa aatcactggc gaaactggct
    47341 tcagagaaaa agaggatctt ttatctcctt tgtccaatct gaatttccgc aaaaaacaag
    47401 tgtatatatt aattctttat tatggggcta taaagatgca ggattcagag aaccagaaga
    47461 aatttttagg gagagtggtt tgctgcatct gttcagtcta tcgggtctac acatccaatt
    47521 ttatttaggg tggctgtatt atttgtttcg acgtatcgga tggccactac acgtcagtat
    47581 tattccgttg agtctactaa ctatctgtta tgtttctatt gcaggaagtt ctatttctgt
    47641 tttgcgtgct agtttgctgt ttttattgcg attgctagtc aaattgctga ataagcatta
    47701 ttccaccatg gacttatttg cagttgtctt ttggcttctt ttactatttg atcctcgatt
    47761 tctttttcat gcgggtggac agcttagttt tttcatgagt tttttgttta tcctgatttc
    47821 ttttgatgga gattggttga aaaaaacggc ctctcacgtc ctgtttacta tgatcacgat
    47881 gccgttgatt gtatggcatt tttatgagtg gcctatttta ggtagtcttt ttacattact
    47941 gattgcaccg gtattcaagt ttctttttct tcctggtgtg ttatttctca cactcttcaa
    48001 tcgctggctg ccggaaactt tacttttgct gatagaagag ggattaatct tatttgagcg
    48061 aataatcgat ttttcttcag ggtcgtctct cattatagga cgtttgcccc ttgtgctatc
    48121 tgggatgtat attttcggat tactgatttg tatggatagg ttgaaagaac aacctgtgaa
    48181 acacttgttt tatgttggtc ttttttcttt tatttttttg actttgccat ttttacgctt
    48241 ttcttcaacg atcgctttta tcgatgtcgg tcaaggagac agtatctttt tgcaaagtcc
    48301 ttttcgaaaa gaaacgattt tgatcgatac tggaggtcag ttacactttg aaagagaaaa
    48361 gtgggcgcaa ggtatgatac gtcctcctgc tgaaagaaat atcgttccat atctaaaagg
    48421 tcaggggata agtgtaatcg ataaactcat cttgacacac gacgatacgg atcatgtggg
    48481 agaattaccc acgttatctc agcattttac tatcaaaaaa atttatatcg gttggggcgc
    48541 tggacgaaat gagccattac aaaggcattt atctgaagct caaaaaaatg gtactgagat
    48601 cattgaaatc aaacatgggg acaggatcag cggttattat gatctttatg tattgactcc
    48661 ttttgaaaag ggagagggaa gaaatgaaga ttcgattggt ctatggatgg aatataacaa
    48721 taggcgcttt ttatttttag gagatttgaa tcaagcaatg gaaaaacaat tgcttttgat
    48781 ttatcctaat ctgaaagccg atgtagtcaa attaggtcat cacggtagcc gtacgtcaag
    48841 taacacagat tttctttccc atattgaagc aaaacatggg attatatcct gcggcgtaaa
    48901 taatcgttat ggtcacccgc acagcgaagt attggagaca ctagaagaaa atcagataaa
    48961 aacatggcga acggatcaac aaggaatgat cacctatcgc tggcatccag tttttcatcc
    49021 tcatgggcta gtggaaacaa tgatagacta gtaattctca tctgctcatg gtaggataat
    49081 ttttgaaagt ggtgagtaat ttgagtatac aagcagagtt acaaaaaata cgtaaagaaa
    49141 aacttgcatc ttgttacttg attttaggaa cagaaaagtt tctccaagat caagttcgga
    49201 cagaaattgt caaaaaaatc caattagagg gcgaagatga cttaaatttt ttaagttttg
    49261 acatggaaaa tgcaagttta gatgaggtag tagctgaagc agagacgttg ccgtttttcg
    49321 gagatcaacg gttagtattc gtagagaatc cttatttttt aacaggtgaa aaagtaaaca
    49381 atggaatcga acaaaatact gatttattga cggcttattt gaaagaacca ttagaatcga
    49441 ctgtattagt attctttgcg ccatatgaaa agttggatga acggaaaaaa gtaacgaaac
    49501 aattgaaaaa aacagcaatt atcatcaatg tccaacagtt gaatgaaaaa gaagtacgtc
    49561 aatatctgat gaatacctta gagaattcct caatcaaaat ggaacgaagt gcaattgatt
    49621 tattcttgag gttgaccgac ttagatttat ccaaaatgat gagagagtta cagaaattgg
    49681 tcctttatgg acaaaatcaa cagcaaatca cggtaagaga agtagaagaa ttagttccta
    49741 aaacgttaga acataatatt tttgacatga cccaatatat tttaaaaggg aagacggaac
    49801 aagctttgcg tttatacgaa gatttagtta tgcaagggga agaaacaatc aaaattaatg
    49861 cgattttgct ttctcaatta cgtttatttt tacagacaaa atttcttgta aagattggtt
    49921 atcagcaggc aaatattgct gaaacattga aaatccatcc atatcgtgta aaacttgcca
    49981 tgcaggaagt aaaaaaattc gatgaacatt tgctggtaca gttgtttgat caattagttg
    50041 agatggatta tcaaatcaaa acgggacaaa tcgaaaaaga attaagtttt caactattcg
    50101 ttttgcgcac agggcagttg ttaagaaatc gataagaaga aagacgaggg caaagcatgc
    50161 gggaaggtcg tttgtttttg tccttttttt gacaaataaa aaaatcggcc gaagccgatt
    50221 cttttattta gcgatttttt tgcttaaacg agatttgtcg cggttagctt tgtttttgtg
    50281 gattagacct tttgattcag ccatatcaat agctttaaca gcttctttat ataacgcatc
    50341 tacgttgtca gcacctgaag ctacagcatc ttcaaatttt ttgattgcag tacgcatagc
    50401 gcttgtttga gatgaatttt tcacattagc gttttcgctt gtacgaacac gtttgattgc
    50461 agattcaatg tttggcatta gtttcacctc cgataactta agttcttacg cgtgttaccg
    50521 cataattcaa cattcattat tatacctaaa ggcagcgtgc tttgcaatat gaacatgaca
    50581 agtttttttc cttaacagtc ttttattagg attttttttc agtaaaaacg gatagtacaa
    50641 gctgaaaaaa atcaaaaaga cgctattgtg ggaggcaata gcgtcaaacc aaactagatt
    50701 tttatttatc tatttaaaca aagtttgaat gggaatgttt ggtactaagt tattatataa
    50761 caaagagaac cgtttgcaaa gttttttttg aaaagggata cgattccctg ttgttctttg
    50821 tttttctatt aagaaactgc agttatttta taaccagtat cctttgatca gtaaaggcta
    50881 ttctggtgta ccgattattt taatgtattc atcgatattt tttatcaaca ttttttttat
    50941 gaccaactgg ttccgacggt tccatttgcc acttacttcc agcacatatt tatttagggg
    51001 caaacgtaag atatattttg ccaaatagcg atctttaagc aggccattga tcacacggtc
    51061 ctcaagctgc aagttgatcc cagtcagcat cattggctgt tcttgtaaaa cgtacgtatc
    51121 aattaaaaga ccttcaaaag tttccacaag cgtcttcctt tcttttcaaa gtaacctgaa
    51181 aacaggcact aattcttcca ttttgatatt cgttgaagtg gatgcgatca ttctttcttt
    51241 tgtccactgt aatctagtat aacaaaaaag agcagaagag ccaaaaagaa aaaagagcat
    51301 cgaattctat aggaagtctc attggcacgg cctaaattat tacaaaacat tgattaaaaa
    51361 aagcccctgc atcgcaggag catcccctat atcgttttaa taggtcaatc aaaaagcagt
    51421 atcaaacaca ttttgtatca aatcaggaaa taatagataa gctaagccca gaatcaaaag
    51481 taccgctaga agaaaccagc cgattgttcc tatgaaatac tttaattttt cgaacattgt
    51541 atcacctcgt tgtcagtata tcacggatca gtaaattggg ggtgttaaga atctcctaaa
    51601 atagacaaaa tttgttctat tttcctaaag caaatacttg taagatacag taagtgatac
    51661 cagaagcaat gaccggtccg gcggcgattc ctcttaagaa gacaacacct aaaatcgtgc
    51721 cgaaaacaag tgcaacagtg atttgtggat cagaagcaat caatcctaca cccttggaag
    51781 ataagacagc cactagccca ccgcaaaaaa cagctaccca gccaataggg gatttaaagg
    51841 cttctaatag atcacgtaga ccgatttctc ctgttgcgat agggattaga atagccgctg
    51901 tgatgatcgt caccccaata ttgattcctt tgccttgaag ccaagggaaa aaggaacggg
    51961 aggctggtat gagcttcata atcaaaacaa aagctgccgc tatcatcaga ctttgatttt
    52021 tagctaaaat tgctacaagt aaaataattc ctaaaaaaag ccaactttcc atgaaatata
    52081 ttcctcactt tcttcgaaac aatcataaca tgtttttaga aagttacaaa agtaggaatt
    52141 catccttcaa gacctattca taagctgttt ttttcataaa ataaacaaaa tcataaaaaa
    52201 acactttgct tatttgacag aagacagccg cgctttgtat agtggacaag acttacattt
    52261 ttttgaagaa tcagaaagat caggtaaagg tcttagtaaa cgcaagccat tcagaataac
    52321 caatattgtg cttccttcgt gtcctacaac tccaagaggt agatttaaaa attgcaggaa
    52381 gttagaagca atcaacaaga gaataacaag aatcgaaaaa ataatatttt gtttgatgat
    52441 ccgccgcatt tttaaagata gccgatgact gtagacaaat ttatttaagt cgcttttcat
    52501 taagacgatg tctgcgatat ccatagcggc atctgtccct tgccccatag cgacacctaa
    52561 agaagcggct gctaaagcag gcgcatcatt gactccatca ccaaccatcg catttacttg
    52621 gtaaagttca ttctcttttt tgactagttg tgttttttct tccggagtac agcttgcata
    52681 gtaatgttca atccctactt gttcagcaat ggcctttgct gtgccagaat ggtcgccggt
    52741 tatcatactt gtatggatgt tttgggattt aaagtaggaa attacttgtt gggtatttgc
    52801 ttttggaata tctagcagac ctaaaacagc aattaactgc tgatctttag aaagataaat
    52861 cacggttttg ccttgatttt ccaaacgttc gatcatttcc gcaatctctt tgctgattat
    52921 catcgtctca ggatcatatg cgtgcttgcc aactttccat tgcgcaccta aataggtagt
    52981 ttgtaatcca aaaccagtaa tttcttctat tggtaagtat tggatttctt caggtattgt
    53041 gcaatcgaaa tattgcaaaa tcgcatgagc aagtggatgc gtcgtttttt gttccatagc
    53101 aacaagaagt tgttgtgcca aatccttttc atcaaagaaa aagctgtcag ttacaactgg
    53161 ttttccttta gtgagcgttc ctgttttatc aaaggcaatc gcttttaatt cagaaagctt
    53221 ttctaaatgg ataccgcctt tgattaaaat cccatttttt gcagaatttg aaagagcagc
    53281 tagagaagct ggtgtagcag atgcgacaag cgcacaagga gaagccacaa ctaataatac
    53341 cattcctcga taaaagcttt catcccaact ccaacctagg aaaaagtggg ggagaaggat
    53401 cattagagga acagcaagca aaatcaattt tacataatta ttttcgattc gttcgataaa
    53461 tgaagctgtt tgagttggcg tattctgcgc ttcttctact aattggataa tcttagcaaa
    53521 gacagtttcg gaactcgttt ttgttactcg aatcgtgatg ggatttcctt gattcagcgt
    53581 tcctgcatac atctcatcgc ctaaatattt ttctacaggc acagattcac cgcttaatgc
    53641 agactcatcg atcgttgcct gtgtgctttc taaaaagcca tctatcggaa cagctgctcc
    53701 tttagcgaca aataccaagt tatccacctt tagttgagaa acatctactt cttgcatttg
    53761 tccattttct tttaataatt gggctttttg tggttgaaga ttcatcaaag cagtaatttc
    53821 tttttgactt ttattagttg tgtattcctc taatgcaccg cttaaacaaa agatgaatgt
    53881 caacattgct ccttcaaagt aattaccgat caaacaggca ccaatagcag ctaaagccat
    53941 caataaatcc acattcagtg tccgatcatt ccacaattct ttcaagcctt ccgatgtttg
    54001 tttatatcca ccgatgataa tggcactgat ataaaaaagt ggggtgatgg taagagagaa
    54061 tcggtcgaag ataaaaccga agatcataaa taaaaggcag ccgattgttg ctgcaaaagc
    54121 ttttttctga ttagtcatcg ttattagacc tccttgtcaa aacaaggata gcataataaa
    54181 aatgtaattg ataataataa cagctaaatg agaacgataa tggttatcat ttggtgatta
    54241 agcttgatgt tgtttttatt atttataatg attattatta aagaaaataa aaaaccagaa
    54301 catttctcaa ataagagaag tgttctggtt ttttctacat tgcaataaac caataaccaa
    54361 tcaaaatgat accaaggata atacgatacc agccaaaagc ggtaaagtcg tttttcttca
    54421 aatagcttag taagaatttg atagctaaga cggaaaccac aaaagatacg aatgttccta
    54481 caagaagaac aacagtttct tccattttga atgaattccc ttcagctaaa tatttgacga
    54541 tcttcaagcc gcttgcgcca aacatgacag gaatccctaa gaaaaatgaa aactctgtag
    54601 cgacaaaacg cgaagcacca atcaagatag atcctaggat cgttgcgcca gaacgggatg
    54661 ttccgggaac aagtgccaag acttggaata acccaacaag aagagctgct tggtacgtaa
    54721 agtcattcag agaagtccaa cgaggtgttt tgtttttgtt gcgtttttcg acaataataa
    54781 aggcaatacc gtaaacgatc aaaacaatgg caactggtaa gaacttgtgg aaatttgctt
    54841 ctaaccaatc atccaaaggc aaaccaatga tgatggctgg tatgcaagca acgatcactt
    54901 taaaccaaag tgtccacgta tctttttttt ctaccgttga tttacttgga gaaaatgggt
    54961 ttaacttgtg aaaataaaga acgacgacag ccaagatcgc ccctaattgg ataacgacat
    55021 tgaacatcga cataaattgt gaactggcat ccagtttgat gaattcatct gctaggatca
    55081 aatgaccagt actactgatg ggcagccatt ccgttattcc ttcaataata ccgagaatca
    55141 ctgctttgat aatatttgca aaaaacataa attccttcct tcccaattaa gatacatctt
    55201 atagtatacc gttatttttt gagaaaccca atctgttttt taatattaag aaaaacttga
    55261 gaaataaagc agataagtac acgaagagaa aaaagaagac aaagccctcg ttcagacttt
    55321 gccttttatg attctctggt aaaaattaaa atatccccat tatagaaacg agtcgcgact
    55381 atgtgttttc ccgttatcga tataagacgt atcattgatg ccgtggatag aaaatcgacc
    55441 gtttgcataa gtgacctttg ttacgctgcc atttaaaagc ccagcacgaa caggctgttt
    55501 aggatcgatc agattaagca aaaaggcgat cgtcaaacca tgagatacga ctaaaacatt
    55561 tccaccacca tttttttcgc agtgatgggc gatatcttca aatcctgtcc atacacggtc
    55621 tcgcaatgtt tcataagttt ccgcccaccc agcggtatct aagttgtata cagcattagc
    55681 aatttgttca aaagaaactt ctgtggtaaa catttcatca tatgttttaa aattcaatac
    55741 acgagggatc acaccccaca tttccatgtc atatccacct tcaagagacc cgaaacacca
    55801 ttctctaatc cttttttcaa taaaataagg aatttctttt cccttagaat gttctcctag
    55861 aataatacgg gcagtttcga ttgcacgacc actgtcacta gaataagcaa atgaaaagtc
    55921 gacatttttt aacccgcgac ctaaataatg aatgccttct tgtccttgct ttgtgagggg
    55981 tgtatcacac cagccttgta ctcgttcaat tgtattgaac atcgtttttc cgtgtcgtac
    56041 gatataaagt gtagtttctg tcattttatt ctcctcctaa gtcgttttaa cgattgaaaa
    56101 aaggatttgt ccttttttcc tgttcaatcg tcgttgcatc gccatgtcct ggatagactg
    56161 caaattcatc aggtaataca aacagctggg tccgaatact atgaagtaat tgttctaaat
    56221 tccctgtata cagatcggtt ctaccgatac ttcctctaaa cagggcgtcg ccagaaacga
    56281 caaaatcatc aaaaataaag ctgacgcttc ctatagaatg ccctggggta gggacgacgc
    56341 gaaaagacat gtttcctaaa gtataagttt tcatttcaaa ttcatattct gcaggcgaga
    56401 caataacatc agcaatatca tcatgtctac cgagtccaga aagattcaaa atcggatcac
    56461 ctagccattt ttgctctagt gggctgacat aaactgggat ttgataatac gcgcgtaaag
    56521 gttccactgc accgatatga tcgtagtgag tatgggtaag caaaatcgct accggctgtt
    56581 ggtttgtttt tttgatttct tgtttgattc gttccgcatc ttctccaggg tcaatgatca
    56641 aaagtgcttc ttcgttgtag accaaataac agttttcttc aatcattcct gtttttaatc
    56701 tttcgatatg catgtgcatt cctccttgat agccaaaact tctttcatcc attagtataa
    56761 cgcattcatt gctaggaaac aaaaacaggt acttatttct ctttacttat ctgaattatc
    56821 agactatatg aaaagtattt ggatattcta aagagaagga aagtaagttt tcatagcatt
    56881 ttaatatgtc cttgttacat tagattcatc caaaaatcca aattctatat cctatatccc
    56941 tgcctaatca gcagggtgtt tttttatgtt tggaaagaga gctctttttg ctaaactagg
    57001 ttttttcagg taatcttaga gagaaagagg tggtggaaat gatcaaacag tcaaaaatat
    57061 ctgtgcggca cttagtagaa tttattttgc gacgtggaag tatcgacaat cgtaaaaaaa
    57121 gtaaccatac tgcattagaa ggagcgagaa tccaccgcaa gctccaaaaa gatgcgggag
    57181 aaaactatga aaaagaagtc tttttaaaaa caacagttca attagatgaa tattacctga
    57241 tcgttgaagg ccgtgcagac ggtattttca aaagagacgg tatttattat atagatgaaa
    57301 tcaaaacctc cgaaccacga tttgaagatt tagaaccaga acaagtggaa cttttctttc
    57361 atcaagcaag ggtgtatgcc tatatctata gtcaagaaca tgatttacaa gaaataaatc
    57421 tgcaattgac ttacttccag acggcagaag aagtgatcac gagaaaggtt gaacatcaga
    57481 caagagagca gttagaaact ttttttaaaa agctgactga agattataaa gaatggcttg
    57541 tttttcaaga aaactggcgc actgtacgca atgcctcttt gatggctttg aaattccccc
    57601 atgatgagta taggaaaggt cagcgtgaac tagcggtagc tgcttataaa acgatccgta
    57661 cgaaacagaa attgtttgta gaagcaccta ccggaacagg aaaaacaatc tctacgttat
    57721 tccccgcttt gaaagctgta ggggaagaag agggagaaaa gatcttttat ctaacggcta
    57781 aaacaataac tagacaagta gctgaagatg ctatgacagc attaaaagat acaggagctg
    57841 aagtaaaaag tgtcactttg acggcgaaag acaagatctg ctttttagat gagacgacct
    57901 gtaatccaga tcagtgccca tatgccaatg gttattacaa tcggattaat gaaggtttat
    57961 gggatctttt gaatcatgag aatcagatca ctcgtgaagt catcgaaact tatgcaagaa
    58021 agcatacact ttgtcctttc gaactatcat tagatgtcag tatctggtgt gacgtaatca
    58081 ttggggatta caattattta tttgatccaa ctgtttattt aagacgtttt tttgaagatg
    58141 aaaaaaacga ggactatctg tttttgattg acgaagcaca taatttggtg aatcgttccc
    58201 gagagatgta ttcggcagaa ctatcttatg aaaaaacgaa acgaagtaag gaagctatac
    58261 caaaggaatt caaaaaactt catcgccgtt tcaacaaact attaaaagaa tttgattcga
    58321 tccgagaaat agcaaaagaa gatcattggg attatcatca tcaaaaagca ccggctgaat
    58381 ctttagtaaa ggcaggttat caattaagcg aaaaaattaa agaatggctg gcagaatttc
    58441 ctgagcaccc atcacaagaa caattgcttc cttattattt tgatttgctt cattttttga
    58501 aggtcagtga attttatgat gatcactacg aaacaacagt cgaaaaaacg tatcgcgatc
    58561 tgatagtaaa agagttttgt attgatccaa gcttgtttct tgagcagtcg ttggataaag
    58621 gaaaaagcag tattcttttt tctgctagtt tttcaccact ctcttattat caggaaacac
    58681 tggggggaca aaaaagtctg gcttacaaac tgccgagtcc tttcccagaa ggaaaccagc
    58741 aagttttcat cgcaaattac ctagagacga cttatcgaaa aagggaacac agtctggcaa
    58801 aattagtaga gacgattcat gcttttgctg atggaaaggt cgggaattat ttcgttttct
    58861 ttccttctta tcaatattta gatcttgcgg tggaagcatt cagacagcaa tatcccgaca
    58921 gcaatgtgct aatccaagaa acggacatga atgaggaaga acgcgaacga tttttaacaa
    58981 aatttcaaac aaatcccgct gaaacattga ttggattttg cgtacttggc gggatttttt
    59041 cagaaggaat cgatttgaga ggggaccgat tgatcggcag tatgatcgta ggtgtaggtt
    59101 tgccgcagat gaatcatgag caggaactga tcaaatcata ttatgatgag aaggaacacc
    59161 ttggatttgc ttacgcttat cagcttcctg gaatgaacaa agtcttgcaa gctggtggtc
    59221 gagtgattcg tggcatggcg gatcaaggaa tcgttgtatt ggcagatcaa cgattttcta
    59281 gtttttctta tcgacgttta ttcccacaac attggcaaac agcaagagaa gtacgaagtg
    59341 ttggggaatt ggaagaagga atacagcgtt tttggttatc aaaagaagca gtaaatcaaa
    59401 aaaacgagga atgacagacg tcagcctcgt tttttgatta acgatagtta gtgaattgca
    59461 actcgattgg taagtcaagt ttacgtaata aagcaatcac agcttgtaga tcatcacggt
    59521 tcttacctgt cactctaatc tgatcttctt ggatttgtgc ttttactttc agtttttcat
    59581 ttttgatagc tgtagtgatt ttcttcgcgt tttcacgatc gattccgttg accaaatcgg
    59641 cagtttgtcg agctttgcca cctagagcgt gttctgattc ggaaaaatgg atatttttga
    59701 ttggcacatt tcttttgatc agcttaccaa ataatacatc tttgatctgt tcgattttga
    59761 aatcatcatc gctcaataca actagattgc tgttctctaa tttgatttct actgtagaat
    59821 ccttgaagtc aaagcgattg gacaattctt ttgttgtttg ctgaatcgca ttttttactt
    59881 cttctgtatt gacttctgat acaatgtcga agctagcatc ttttgccata ggaaccctcc
    59941 tgatatacat ataaatattt accatacatc tatcttatca taggattagg gcagattctt
    60001 acctgtttgc taaaattctt ctcatttgag ttcgaagtat tttattttaa tagataaact
    60061 gttattctta catttggaat accaaagtag gggagaggtg cttgtgagta aaattatgac
    60121 tgcgtatcat aaaaatgaaa gattaaagaa aatagtggtt attttgataa ccggattgac
    60181 cgctgcggtc gctttaaatt attttttgat tccagccaat gtcttttctg cagggatgaa
    60241 tgggatcgct caaatcattt cctcgctttt atatgaatgg tttcatatca agatagacac
    60301 aggaacattt atttttcttt tgaatatccc tgtgtttgta ttagggtttc tcaaagtagg
    60361 aaaacgagca acgatcctta gttttgtgaa tgttgtatgt gtatcggtga tgacgatgct
    60421 gcttccagtc ggacagatca ctgataatat tttgatgaat gccctagtag gcggtgtttt
    60481 attaggtctt ggcgtaggat tatctttaaa aatgggcttt acaactggtg ggatggatat
    60541 catctctctt gtactttcac aaacaactgg aaaaacagtc ggaaactaca tgctgattct
    60601 aaatggtatc attgtagtca tcgcaggctt cttctttaac tgggaaagtg ccttgtatac
    60661 gattatttcc atttatgcaa tgactcaagt aattgatgcc atccacacga gtcatcaaaa
    60721 agtaacagca atgatcgtta ccgtcaagcc agaagaggta acagaagaac tagcaaaacg
    60781 gatggtacgt ggaatgacat tactgccgtc tgtcggtggc tattcaaaaa aacaagggaa
    60841 catgatcatg atggtcatca cccgctacga aatgtatgat cttgatcaga tcgttcatga
    60901 aatcgacgac gatgcattta tcaatatttt accaactcat tcagtatttg gccggtttgc
    60961 aaatgaaaac gaacaaaaaa tgtatcgaac aactggcgta ttgccagaaa taaaaaatcg
    61021 ttcacaaaaa aaatgaggaa tcaggtttat tttagaataa atttaatcta ttacatctaa
    61081 taagaacatt tttataaatt taaacgagaa tcttacttct aaattctcat ttacaagcag
    61141 ctaaaaaaag agtatgataa ataaaaatcg tgttaaggag tgtcgtacga tgagcgaagc
    61201 aaaccaagaa cggtctggac aagaaataga actaatcaaa gaacgtattc ttgctgcctt
    61261 ggaaatggtg attgatcctg aattaggaat cgacatcgtc aatttaggct tgatttatga
    61321 tatagaattc aatcctgaaa atggagaaac agtcattaag atgactctaa caactatggg
    61381 ctgtccatta gcagatattt taacagaatc tatccatgac gcattaaaag aagtgccaga
    61441 agtaacgaaa gcagaagtca aactagtctg gtatccagca tggacgacag ataagatgag
    61501 ccgttatgca cggattgcgt tggggatacg atagaaatct tggctgacta gctatgagaa
    61561 gcaaatagga aaaacaaaaa agccttttat cctttctaga agaaaagaga taaaaggttt
    61621 ctttgtttat aaaattttgt ct
//
LOCUS       DACCVZ010000006        61485 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.006, whole genome shotgun sequence.
ACCESSION   DACCVZ010000006 DACCVZ010000000
VERSION     DACCVZ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61485
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.006"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..831)
                     /locus_tag="IVW63_000368"
     CDS             complement(<1..831)
                     /locus_tag="IVW63_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP7858671.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     Y"
     gene            complement(1055..2995)
                     /gene="thrS"
                     /locus_tag="IVW63_000369"
     CDS             complement(1055..2995)
                     /gene="thrS"
                     /locus_tag="IVW63_000369"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAP7858672.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3332..3511)
                     /locus_tag="IVW63_000370"
     CDS             complement(3332..3511)
                     /locus_tag="IVW63_000370"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HAP7858673.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3558..5381)
                     /gene="cadA"
                     /locus_tag="IVW63_000371"
     CDS             complement(3558..5381)
                     /gene="cadA"
                     /locus_tag="IVW63_000371"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAP7858674.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5659..7938
                     /locus_tag="IVW63_000372"
     CDS             5659..7938
                     /locus_tag="IVW63_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7858675.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8031..8678)
                     /locus_tag="IVW63_000373"
     CDS             complement(8031..8678)
                     /locus_tag="IVW63_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858676.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8857..9576)
                     /locus_tag="IVW63_000374"
     CDS             complement(8857..9576)
                     /locus_tag="IVW63_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP7858677.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9707..10858)
                     /locus_tag="IVW63_000375"
     CDS             complement(9707..10858)
                     /locus_tag="IVW63_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAP7858678.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11075..11815)
                     /locus_tag="IVW63_000376"
     CDS             complement(11075..11815)
                     /locus_tag="IVW63_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7858679.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11819..12142)
                     /gene="rsfS"
                     /locus_tag="IVW63_000377"
     CDS             complement(11819..12142)
                     /gene="rsfS"
                     /locus_tag="IVW63_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAP7858680.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12199..12792)
                     /locus_tag="IVW63_000378"
     CDS             complement(12199..12792)
                     /locus_tag="IVW63_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP7858681.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12776..13423)
                     /locus_tag="IVW63_000379"
     CDS             complement(12776..13423)
                     /locus_tag="IVW63_000379"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAP7858682.1"
                     /translation="MNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLV
                     MAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELA
                     RGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGY
                     TTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13436..13747)
                     /gene="yhbY"
                     /locus_tag="IVW63_000380"
     CDS             complement(13436..13747)
                     /gene="yhbY"
                     /locus_tag="IVW63_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAP7858683.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13763..14872)
                     /gene="yqeH"
                     /locus_tag="IVW63_000381"
     CDS             complement(13763..14872)
                     /gene="yqeH"
                     /locus_tag="IVW63_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HAP7858684.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14869..15396)
                     /locus_tag="IVW63_000382"
     CDS             complement(14869..15396)
                     /locus_tag="IVW63_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HAP7858685.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15576..16361)
                     /locus_tag="IVW63_000383"
     CDS             complement(15576..16361)
                     /locus_tag="IVW63_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAP7858686.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16354..17223)
                     /locus_tag="IVW63_000384"
     CDS             complement(16354..17223)
                     /locus_tag="IVW63_000384"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAP7858687.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17224..18603)
                     /locus_tag="IVW63_000385"
     CDS             complement(17224..18603)
                     /locus_tag="IVW63_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAP7858688.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18611..19030)
                     /gene="fabZ"
                     /locus_tag="IVW63_000386"
     CDS             complement(18611..19030)
                     /gene="fabZ"
                     /locus_tag="IVW63_000386"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAP7858689.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19055..19531)
                     /gene="accB"
                     /locus_tag="IVW63_000387"
     CDS             complement(19055..19531)
                     /gene="accB"
                     /locus_tag="IVW63_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAP7858690.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19534..20769)
                     /gene="fabF"
                     /locus_tag="IVW63_000388"
     CDS             complement(19534..20769)
                     /gene="fabF"
                     /locus_tag="IVW63_000388"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAP7858691.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20788..21525)
                     /gene="fabG"
                     /locus_tag="IVW63_000389"
     CDS             complement(20788..21525)
                     /gene="fabG"
                     /locus_tag="IVW63_000389"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAP7858692.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21537..22454)
                     /gene="fabD"
                     /locus_tag="IVW63_000390"
     CDS             complement(21537..22454)
                     /gene="fabD"
                     /locus_tag="IVW63_000390"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAP7858693.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22561..22785)
                     /locus_tag="IVW63_000391"
     CDS             complement(22561..22785)
                     /locus_tag="IVW63_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAP7858694.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22838..23800)
                     /locus_tag="IVW63_000392"
     CDS             complement(22838..23800)
                     /locus_tag="IVW63_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAP7858695.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23810..24250)
                     /locus_tag="IVW63_000393"
     CDS             complement(23810..24250)
                     /locus_tag="IVW63_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7858696.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24556..25521
                     /locus_tag="IVW63_000394"
     CDS             24556..25521
                     /locus_tag="IVW63_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAP7858697.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25578..25808)
                     /locus_tag="IVW63_000395"
     CDS             complement(25578..25808)
                     /locus_tag="IVW63_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HAP7858698.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(25894..26781)
                     /locus_tag="IVW63_000396"
     CDS             complement(25894..26781)
                     /locus_tag="IVW63_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAP7858699.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(26870..28093)
                     /locus_tag="IVW63_000397"
     CDS             complement(26870..28093)
                     /locus_tag="IVW63_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP7858700.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28110..29189)
                     /locus_tag="IVW63_000398"
     CDS             complement(28110..29189)
                     /locus_tag="IVW63_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP7858701.1"
                     /translation="MLYYISEGGRKVKVLLYFESEKMLAKSGIGRALDHQKRALTEVG
                     ISYTLDEKEDYDILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQL
                     SPIVKKYLVGLYQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQ
                     KFREYFKLSPDQKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIR
                     KIVKEDHPENVLFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVR
                     DIPVYNGWLEDSKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEE
                     LKNVYESVLNEKVSSKLKKVNQVKD"
     gene            complement(29320..31047)
                     /gene="ptsP"
                     /locus_tag="IVW63_000399"
     CDS             complement(29320..31047)
                     /gene="ptsP"
                     /locus_tag="IVW63_000399"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAP7858702.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(31047..31313)
                     /locus_tag="IVW63_000400"
     CDS             complement(31047..31313)
                     /locus_tag="IVW63_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HAP7858703.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            31792..34026
                     /locus_tag="IVW63_000401"
     CDS             31792..34026
                     /locus_tag="IVW63_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAP7858704.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34174..34494
                     /locus_tag="IVW63_000402"
     CDS             34174..34494
                     /locus_tag="IVW63_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAP7858705.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(34699..34923)
                     /locus_tag="IVW63_000403"
     CDS             complement(34699..34923)
                     /locus_tag="IVW63_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HAP7858706.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(35121..36701)
                     /locus_tag="IVW63_000404"
     CDS             complement(35121..36701)
                     /locus_tag="IVW63_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAP7858707.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(37102..38478)
                     /locus_tag="IVW63_000405"
     CDS             complement(37102..38478)
                     /locus_tag="IVW63_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAP7858708.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(38606..39724)
                     /locus_tag="IVW63_000406"
     CDS             complement(38606..39724)
                     /locus_tag="IVW63_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP7858709.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            39866..40300
                     /locus_tag="IVW63_000407"
     CDS             39866..40300
                     /locus_tag="IVW63_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7858710.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(40378..40911)
                     /locus_tag="IVW63_000408"
     CDS             complement(40378..40911)
                     /locus_tag="IVW63_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HAP7858711.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(41005..42183)
                     /gene="mutY"
                     /locus_tag="IVW63_000409"
     CDS             complement(41005..42183)
                     /gene="mutY"
                     /locus_tag="IVW63_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAP7858712.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(42176..42973)
                     /gene="recX"
                     /locus_tag="IVW63_000410"
     CDS             complement(42176..42973)
                     /gene="recX"
                     /locus_tag="IVW63_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAP7858713.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            43080..44462
                     /gene="rlmD"
                     /locus_tag="IVW63_000411"
     CDS             43080..44462
                     /gene="rlmD"
                     /locus_tag="IVW63_000411"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAP7858714.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(44636..45214)
                     /locus_tag="IVW63_000412"
     CDS             complement(44636..45214)
                     /locus_tag="IVW63_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin-binding protein"
                     /protein_id="HAP7858715.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            45536..46006
                     /locus_tag="IVW63_000413"
     CDS             45536..46006
                     /locus_tag="IVW63_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAP7858716.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(46114..47340)
                     /locus_tag="IVW63_000414"
     CDS             complement(46114..47340)
                     /locus_tag="IVW63_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HAP7858717.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(48094..48294)
                     /locus_tag="IVW63_000415"
     CDS             complement(48094..48294)
                     /locus_tag="IVW63_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP7858718.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(48428..49036)
                     /locus_tag="IVW63_000416"
     CDS             complement(48428..49036)
                     /locus_tag="IVW63_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAP7858719.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(49121..49591)
                     /locus_tag="IVW63_000417"
     CDS             complement(49121..49591)
                     /locus_tag="IVW63_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAP7858720.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(49639..50553)
                     /locus_tag="IVW63_000418"
     CDS             complement(49639..50553)
                     /locus_tag="IVW63_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAP7858721.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            50699..51502
                     /locus_tag="IVW63_000419"
     CDS             50699..51502
                     /locus_tag="IVW63_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HAP7858722.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            51680..52627
                     /locus_tag="IVW63_000420"
     CDS             51680..52627
                     /locus_tag="IVW63_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAP7858723.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(52695..52988)
                     /locus_tag="IVW63_000421"
     CDS             complement(52695..52988)
                     /locus_tag="IVW63_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HAP7858724.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(53016..53681)
                     /locus_tag="IVW63_000422"
     CDS             complement(53016..53681)
                     /locus_tag="IVW63_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAP7858725.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(53821..54453)
                     /locus_tag="IVW63_000423"
     CDS             complement(53821..54453)
                     /locus_tag="IVW63_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7858726.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(54460..55527)
                     /locus_tag="IVW63_000424"
     CDS             complement(54460..55527)
                     /locus_tag="IVW63_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP7858727.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(55524..56255)
                     /locus_tag="IVW63_000425"
     CDS             complement(55524..56255)
                     /locus_tag="IVW63_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAP7858728.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(56424..56903)
                     /gene="greA"
                     /locus_tag="IVW63_000426"
     CDS             complement(56424..56903)
                     /gene="greA"
                     /locus_tag="IVW63_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAP7858729.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(57039..58214)
                     /gene="mltG"
                     /locus_tag="IVW63_000427"
     CDS             complement(57039..58214)
                     /gene="mltG"
                     /locus_tag="IVW63_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAP7858730.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            58418..59587
                     /locus_tag="IVW63_000428"
     CDS             58418..59587
                     /locus_tag="IVW63_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAP7858731.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(59854..61476)
                     /locus_tag="IVW63_000429"
     CDS             complement(59854..61476)
                     /locus_tag="IVW63_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858732.1"
                     /translation="MNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAFHINR
                     ALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLYIVTL
                     ITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPLILLG
                     FIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIFLIIK
                     LIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDSELLS
                     FGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLNIIQA
                     PWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNMVKEM
                     NFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPNKDEI
                     TFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTIRYSY
                     TFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT        17992 a        12802 c        10320 g        20371 t
ORIGIN      
        1 atattcttgg attgcttctc gtgttttttt cactttttcg ctaagctttt cgtttttagc
       61 catatagaaa taaaaaatga tatcgatcgt agcaaattgg gccaaaagtg aattagttgc
      121 cgcacttcga ttcgtgattt cttttggtct agatgtttgt acgagtacat cggctatctt
      181 gctaagcggg ttatttccaa attgcgtcaa cgcaatgatt tcgatattca tgcttttcgc
      241 cagctcggct aatgcgacta catctgcact tctacctgag tttgaaacaa gccaaagcac
      301 tttctttttc tcattgctga caagttgcgg gagcaagacg tggatatctt tttcaaaaat
      361 gattggctta ccgacacgag accatttttg cagaatatct tctactacta aagaagaggc
      421 gccaacccca tataaaaaaa cagtctctgc cgattccaaa cactctacga ctttttggat
      481 cgtttcttct tctagaatat ctactgtttc ttttatcgct acttgtgcat tgttaccaag
      541 tttgtttttg atagagtaaa aggactcatt tgcttctata tcactaaaac cttcatcgat
      601 tccagtctgt agttctgttg aaatcgtgat tttgaagtcc gtcagacttt gaaaaccgat
      661 ttttttggaa aaacgtacaa ctgtcggcgc actcaacccg gaagcttctg ctaattcatt
      721 agctgtcatt gtagggacct tctcaatatt accgataatg tagttggcca actttttttc
      781 tgctgaagaa taatcttcca tcatactttc aatacgacta attacgctca taagttcctc
      841 caccctttta atgatagtct atgtaagtat accatatcag acccttattc acggtcgtat
      901 actggataaa aaacaaaaaa acaatccgcc caacagaata tcttatccca tcaatcccac
      961 agattctatt gagcatctgt gtctttgagg aatacctgtt atctattgtt cggattgctt
     1021 tctatctact acttttttac aggaaattta cctattagtt ttctctgctg taatttttga
     1081 cttctgcttc catagcatca ataaagatat tcaaatcttc tacagctgtt tctttacttc
     1141 cataacgacg tacgttcact gttgcatctt ccaattcctt gtctccaaca actaattggt
     1201 aagggatctt ttgtgtttga gaggcacgta tcttatagcc cattttttca ttacgatcat
     1261 caacttctac acgcaacccc ttcatttgca aacgttcttt gatttcataa gcataatcgc
     1321 catgtgcatc aacagaaaca gggatgattg ttgcttgtat aggtgccaac catgttggaa
     1381 aagcgccttt gtatacttct gttaaataag cgacaaaacg ttccattgta gaaacaattc
     1441 cgcggtggat aactactgga cgatgcgtat tttccccgtc ttctccaaca tatgtcaaat
     1501 caaagcgctc tggcaataag aagtctaatt gtatagttga taatgtttct tctgtaccaa
     1561 gagctgtttt gacttgaaca tctagttttg gtccgtaaaa ggctgcctcg ccttctgctt
     1621 caaagtaatc tagttctaat tcatccatag cggctttcag cattgcttgg gctttttccc
     1681 acattgcgtc atcatcaaaa tatttatctg tattgtttgg atcgcgatag ctcaagcgga
     1741 aacgataatc tgtaatattg aagtcagcat atactgccac catcaattca agcgtacgtt
     1801 taaattcatc tttgatttga tcaggacgaa caaatgtatg accatcattc aacgtcattt
     1861 ctcgtacacg ttgtaaacct gacaaagcac ctgatttttc atagcgatgc atcattccta
     1921 attcagcgat acgaattggt aattcacgat aagaatggat cgtgtttttg tagaccatca
     1981 tgtgatgagg gcagttcatt gggcgaagaa caagcatttc gccatctccc atatccattg
     2041 gcgggaacat gtcttcttga taatgatccc agtgtccaga tgttttgtac aactcaacat
     2101 ctcccattat tggtgtatat acatgttggt aacctagact aacttctttg tctacgatat
     2161 aacgttcgat cgtgcgtcgg attgttgccc cttttggaag ccagaatggc aaaccagaac
     2221 ctacttctgg ggaaaccatg aacaagtcaa gttcttttcc tagtttacga tggtctcttt
     2281 cttttgcttc ttcacggaga cggatatatt ctttcaaagc tttcttgtca aaaaaggctg
     2341 tcccgtatac acgttgcatc atttgattgt ttgagtttcc acgccaataa gcacctgcca
     2401 ctgataataa tttaaatact tgtatacggc cagtggatgg aacatgtggt ccacgacaca
     2461 aatcgatgaa ttcgccttgt tgataagcag taatcacttc ttcttctggc aattcactaa
     2521 tcagttctac tttgtacgga tcacttgcaa aaatttctaa tgcttcctgt tttgaaagaa
     2581 cacggcgttc gatcggcaga ttttctttga cgattttcat catttctgct tcgattgccg
     2641 gcaaatcttc tgcagttact tggttttgtc cattatctgt atcgtagtaa aaccctgaat
     2701 cgatagctgg tccaacgcca aagtggatat ttggatagag gcgacgcatg gcttgggcca
     2761 tcaaatgagc tgctgaatga cggactaagc caagtgcatc ttcatggtct ggtgtgatga
     2821 tctcaatact tgcatcttcc tcgattggac gagtcaaatc aacgagtttt ccgttcactt
     2881 taccagctaa agcttttttt gctaagcttt ttgaaatgct ttcagcaatt gccaatgttg
     2941 ttgttccaga ctcaaattct ttgactgcac catctggaaa agtaattttt atcataatag
     3001 tttcctcctt gaaatgtttt gattgatcag atcatcaagc tgaaaaacaa aaaaatccta
     3061 gcatctcttg aaaagagata ctaggacgaa aagttcgtgg ttccacctaa tgttcaaacg
     3121 caaatgcgtt cctcaagcgt tgtaacggtc cgaccgccct tgcttcaaca agggtttcga
     3181 aagtggtcat cctttggttt tctcctggaa aagtttcagc ctagcttttc ctctcttatc
     3241 gaagactctc aaattcagtt ggctttctca tcaatcaatt atgtgtttat ttaaccacta
     3301 ataaatagaa aaatcaagtg ggaaactaaa cttatttttt ccattcccca tttacaccgt
     3361 atgttccttt tttcatctca ttgatgatga catggatgtg ttcttttggt gcctgcgtgt
     3421 ttttatgaac agcttccgtg atatctttca tcatattttc taattgttcc ggactgcgac
     3481 cttctactaa ttcgacatgt acgaatggca taatgctctc tcctctttct gatcgttctt
     3541 ttttcaactc gattctatca tactatgttt gtcttgggta ctgaatcagg aaaaatggct
     3601 ggatcttttt ttgctctcaa ggcactcaaa atagagaccg tatccacgac ttcttgcaaa
     3661 acagctccga ataatgcggg gattagtccc gtacttgcaa ttaacatcaa aaaaatacaa
     3721 ataaagatgc caatcagtac agactgtttc gctattctca tcgtatctct tgaaatcact
     3781 actgcttttg ctacacgcaa gagatcatct ttcaagatga ccgcatctgc actttcacta
     3841 gcagctgtag aaccatgagc ccccattgca ataccgatat ctgcagcagc aagtgctggt
     3901 gcgtcattca cgccgtctcc taccatcgca acaggtcttt gatctttagg gatactttct
     3961 aaaatggtca gtttatcttg aggcaagcta cgggcatgta cagaatctaa ttggactttt
     4021 tctgcaatcg tttgagcaat ggcagatcca tccccggtga tcatcatcaa atttttcaca
     4081 tcaagttttc ttagctcctt gattgtcttt gctgcttctg ggcgaatctg atccgaaaat
     4141 aggatcgttc ctgcaaaaga tcgatcaatt gttacataga ttgctgtatt ggacgtttct
     4201 atttcttcag ctgaaacaaa agaggcacgt ccaatcttta cttcatgatt attgactact
     4261 gcttggattc cttgaccggt cacttctttc agttgactaa caggatacag ttggctgttt
     4321 ttcacgttgt tcactaacga acgagctaag atatggctag attcctgttc tgcactagct
     4381 gcatacagaa gtagctcttc tttttttatt ccattgactg gctgaatcgc ctctacttcc
     4441 aatatccctt tggtaagcgt tcctgtttta tcaaaagcaa tcgtttttgt acgtgcgagc
     4501 ttttcaatcg ttgttccagt ttttacaacg atcccgtttt tacttgaacg gctcattcct
     4561 gcaactaaag caatgggcgc agctagaatc agtggacaag gtgatgccac taccagtacc
     4621 tcagcaaatc gtaaagggtc ttttgagaac caccaagaaa taccaccgat caaataagca
     4681 atcaacgtga aagggactgc ataacgatca gctaaacgga caaatcgggc aggcttttct
     4741 tttgattctt cgactagttt aataatcatt tgatactggc tgtctgcggc acgtttttca
     4801 gcgatcattt ggatcgatcc gtctccattt aaagaccctg acataatctg atctccaggt
     4861 ttcttggttt ccgggcggga ctcacctgtc aaagaagatt catcgaccga agattctcct
     4921 ttggtcactc gaccatctgc gggtacaagt tcgccaggct tgactagtaa ctggtcatca
     4981 atatttattt catcgattac tatatcctgc aattttcctt ctttgaatcg atgggcaatt
     5041 cttggggtgt tatctaacaa agactgcagt tctttacccg ctcgtttatt cgcgtaatcc
     5101 tctagactat ctccgcccgt aagcatgatc aatatcatca aactagccca gtattctttg
     5161 acggctaatg ttgcaaggat tgcggtaatc gctaatacat ctacgccata tcttcctgaa
     5221 cgtaacgtct tgatcatttc caaaaacatc aagaaggcga gaatccctcc agtaaatgcg
     5281 acaatcgcaa atgcaagggc cggctggtga aaaacaaatt cacttaataa agctatccca
     5341 ccaataagca aagtaagtaa aaattttttg aaatgtgtca ttgttttttc tcctctttta
     5401 tgtgacttag agaggttagt aataaatttc cagctgcctc tttcatctta agcatagtcc
     5461 ttgactagca ctttttaaaa caataggcct taattgaaaa caactatcac tatcagcgtt
     5521 tccaaaattc atcagttcta caaacaaaaa tattcagcaa ggattacttt ttcgattcat
     5581 cagttaaaaa gtaccttttt tcgaaaaact atgctatact tttaattcgt tatttacggc
     5641 ggaaggagca aacatgcgat gaatgagaaa caactagaac aaacgcacgt ggatgaaacg
     5701 atcgaactaa tccagatcga acaaaatatg ctggatacaa aacaacaaga attgactcag
     5761 gaaatgaatc attcgacaaa agacacagct aatcacaaga ttcgagctgg ttccaatgaa
     5821 gctttttatg aatctgctgt tgaatatcgc caacatgagc aggaattgct tttgaaatac
     5881 catactcttg aagcacagca aaaacgcctg caaacgttgt ctgtcatgaa agatagtcct
     5941 tattttgccc gtatcgactt taaagaagac cgtgaaacag aaacattata tctaggtatc
     6001 gcttctttaa gagatctggc agaagaaaca atcgttattg actggcgcgc accaattgcc
     6061 aatctttatt atgaaggtga gattggtccc gcattttatg aaactgaaac agatagaata
     6121 gatgtcgatc tgcagttgaa acgacaattt aaaatccaag aaggacgtat tttatctatg
     6181 gtagatacgt cggaagtaat caatgatgac tttttgctag agatattgga tgaatcatca
     6241 agcaaccata tgaaaaacat cgtctctacg atacaaaaag cacaaaatgc aatcattcgg
     6301 gacacaacaa gtaaagtaat gctgattgaa ggaatcgccg gaagtggaaa gacatccgct
     6361 ttgcttcaac gtattgcttt tctgttgtat cataatcgca agtggctcga ggctgaaaac
     6421 gttcttctat tttcacccaa ccatttgttt tctgattaca tctcgactgt attgccttca
     6481 ttaggtgaaa gcggcgtgcc tacacagaca ttcaaaaatt atttggtgca gctgctgcca
     6541 gagttttctt tactagatga acagcaacaa gaaagtggtt ttttgctagg ggaaaaagat
     6601 ccgatacaag tgatgaaaag cggattgacc ttagtcgatc agattgatcg ctatatccaa
     6661 ggcatcacaa actacggtcc cttgttccgt gatatgaaaa taaatggccg tacgatccta
     6721 tcaaaggaat cgattcgcca atggtataaa gaaacaaatg aacaattacc tttacatcat
     6781 agactttctc tattacaaac gaagctcctg aaaaaattag gcggtctgca aaaagacgaa
     6841 acacgtcagc aatgggtcaa agatctggcg gaagaacagc tccaagaact atacgcaaca
     6901 gatccaaatc ttgaatatac agaacaaaag gagcgttcat tacgtaaaaa actggccaac
     6961 caaatcgtac gtaaaagatt ccgtcgaatc catcgaggga tcatgaatta tcaatttgtc
     7021 aatataacga aacaatatct ccactttcta caaactgtgc cactttctct tctaacacga
     7081 cataaaatca gcgagaccag gtggcaggaa catttgacaa ctgttcgtac acacttgcgt
     7141 caaagagaat tgcgtcaaga ggatgctgta ctattctttt tactgatgcg ccgaacatat
     7201 ccagtgacgg ttacacacaa agctcgctat atctttattg atgaaatgca ggatttcgca
     7261 ccatcacaag tggcattgct gcaagccttg ttcccaaaag caaatttgac tttctgtgga
     7321 gatctaaatc aaaatgtctt tggaaatgaa acgatcgttg gatcattgga agaccttttc
     7381 gtggaccgtg aagtcactcg tttccaatta acgacaagct atcgctccac aaaagaaatc
     7441 actgattttg ctaatcattt tattgtgaaa gaacatcaag tagaaacaac agcaagaaaa
     7501 ggagaccttc ctttgctcat ccaaggaaca acagatgata tcaaattgaa ttggttagca
     7561 gataccattc gaacgactca gggaaaagcc cggtattggc gtacagcaat catagctaaa
     7621 acacaagaag aatgcgaagc tctttatgct caactgccag acgagttgaa acaacaagtc
     7681 cagctgattt taaatgagag tgactttatg aagcgttcca ttattttact tccagccttt
     7741 ttagcaaaag gtctggagtt tgaccgagtt ttcttgtggg atgtagatgc agaacatttt
     7801 tcttctcagc aagacaaatt gatcctttac accatgtgta cacgtgcgat gcatgaattg
     7861 acccttttta cctccaataa tgaaagtcct ttgttaaaca atatggatat ttcatcttat
     7921 gagaaaaaag tactgtaagt aaaaagacaa ctgctatcat taatgttagc agttgtcttt
     7981 ttatttacaa taataattgc agaaaaagta attcaatcat ttaaggtcat ttattctata
     8041 tataaatcca aatctgtttc aggatatttt aatttgacaa gcgaaataat cattttcagt
     8101 tcttccatgt tttctggata ttctgggtca aataccttgc tatgacggcc aatcccgcca
     8161 ttgtcgatca atcggtaaat tcgattccat tcaatgaatt ggtcaattga ttggaaattg
     8221 ctgattggat agccgccaca atccaaaatc tctgatacac gaaatgctag gtatgcacta
     8281 tcgatcactt tatttttttt cgtgtctatc ttctcatttc tttcgataag aattttttca
     8341 ggacgatgtt tcaagctcca ctctaatagt agaaagaaag cctccatccg atactcttct
     8401 tcaaataacc gaaaggctga atcagaacga cgaaaaagca gcggaatcag ataattttgt
     8461 ctataaatca gcattggtgc gcggtccacc atacactcta aataacggtt cagataccct
     8521 gtaccgacat agtttcctaa tcgatagcct tcaacgccga atcttgcgta tttttgcgct
     8581 aattttgaac aatcagttac gttcacagct aactcttcta ctttgcggta accgcttaag
     8641 atacgttcaa aaggttctaa agtgattttt gcttccatat tcttccccgt ccatcttcca
     8701 catacttcat atcatttcac atgatactta tgctctcatc ataccacagg ttgaattaga
     8761 aaagaaaata aatcacacaa aaaagcaaga caatctgtta gtgagattgt cttgcttttc
     8821 gaaaaagact gaatactttt cgttaaaact ggttgcttag tcttctaatg ccacattatg
     8881 gaacacatgc tgtacatctt ctagatcttc cagtgcatca atcatttttt caaatgtttc
     8941 ttgatcttct ggagatagtg ttacctcgtt ttgagggatc atttggatct cagcgattga
     9001 aaaatcagtg attccttttt cttttaatgc ttcttgtata ctatggaaat ccgctacttc
     9061 accgtaaacg atgatttgtc cttcttcttc cattacatcg cgaacatcga tgtctttttc
     9121 cattaggtat tcaaggatct cgtcagcgtc ttctcctgca aaagcaaaga ttgctgtatt
     9181 gtcaaacatg taagaaaccg ctccggaaac acccatgttc ccgccatttt tcccaaatgc
     9241 tgcccgtacg tctgctgctg ttcgattcac attgttcgtc aatgtatcaa caatcaccat
     9301 tgagccgctt ggtccaaatc cttcatagcg caattcagag tatgtttcat ctcctgcacc
     9361 ttttgctttt tcgattgctc ggtcaataat atgttttggt acattataag ttttagcgcg
     9421 atcaatgacg aaacgtagtt tttggtttgc atgcggatca ggatcacctg attttgctgc
     9481 cgcgtagatt tcaatcccaa attttgcata aatccggcta ttattagcat ctttagcagt
     9541 tttctttgct acgatatttg cccatttacg tcccatattt tcacttcgct ttctgatttg
     9601 atagtttcat aacgcaaaaa cgtcctgttc cattatactt gtgaatcacg attctgtgaa
     9661 gctttttttc tttcttcctt cattcttctc atttttagtc aattatctat actcggattg
     9721 ggatttgccc gaaattctgt tccggaatat tgcctcccaa ttgatagatt tgatcacttc
     9781 taactaacag ttccgcttct tgtgcctctt tttttccgat tcgggaataa atagaaatct
     9841 cttttttttc ttttaagaat cttcttccag catcggtaaa tccaagtagt cgaagataat
     9901 ttttattttg ttggacagga atctcttgct ttttgatatt cagcaagaca taacaagata
     9961 atcgttggat ccgtgtccat gtatatcttt ttgtttttac ctttgacaca aaatcctcaa
    10021 aactatcagc agttgcagct gctgttttca tgcgcgattc tattccttcg gtcatctgat
    10081 agatatctgt cagttccagc aaagtagaag ataacaaccg ataacgcaaa tacggccaat
    10141 aagattccca agtctgcagc gaacaagttg aaagatcttc ttctgtctga ggcggcacaa
    10201 gtccagctat tctttttcct tcttctaacg catggcgaat ggctgttgca ctggctatcc
    10261 tctgatctgt gatgattttt tcatgatagc ctgcactttt acgtcggatc ggatgtaatt
    10321 ccatagggtg gacatacttg gcattttcct ttgcataact taatcccaag atatgatttg
    10381 gcgaagaaaa atcaagcgta atatcgggat acagactgcg aaaaacctca gtcatttttt
    10441 gcggataact atacgtttga tcagacagtt cttgaaatgc ctcttctatc ctatcttgat
    10501 tctcttggac aaagcgtccg aaactgctgt aatcaaacga agtctcttct tctgttccaa
    10561 aacacaaact gtcacagtcc agtgtttgca agatttttac tgcaccttta gcaaaatagt
    10621 cagctgactg aaccgcccat tcgacgggaa gctccactac taaatccaca ccattttgta
    10681 aagcttcatt cgcgcgatgc catttatcga tgatagccgg ttcgcctctt tgcaaaaaat
    10741 tcccgctcat tacagcaatg acgacctctg ctcctgttat ttttcgtgcc atttccacat
    10801 gatagcgatg tccattgtga aaaggattgt actctacgat aatcccgcag cttttcatgc
    10861 gcatcctcct tcatagttat cgataaaaaa gaaatagaga caagtaaaaa aaggcaaaaa
    10921 tcggaaaaaa tacccgaact atataaacta ttctcgcaaa cacaatactt ctgcgacgaa
    10981 aagctgcact gcaagagcaa tgcctatatc gttcggatat ataatttatg ttgaagattt
    11041 attcttttct tgttaactcg agcaggcaaa accgctagtc tttgtatgct acaaagaacc
    11101 agcgctttga tttctctgat gctgcttcgt ctgtaaaatc agaaaatgct tcgactttcg
    11161 aaaagccgct gttttccagc attcttaaat aactttccaa tggataggta cgctcttgat
    11221 gtagttcatc ttcacgaata aatcgaccag acccttcttg ttcttcaacg aaaaaggtaa
    11281 gaaaatgttc gatgctgtgt ttctcgcttc ctggataact atcccacaaa aaagcaaaat
    11341 tatccccttg ataatgatag ctatattctg gaaaaacctc atctacttga taggtggagt
    11401 gtacgtcaaa taaaaatcgg ccattttctt ctaacgcttg atagacttca tcaaacactt
    11461 gctgtacctc ttgtctattt ttcatatagc acagcgaatc agaaaaacag gtaattgcct
    11521 gatattgtcc gatttctgat aaatcgagca tattgccttc cacaaattgg atcgatgcgt
    11581 cttcttcata tgctcgctgg ctggcaatca tcaacatctc ttctgaaagg tctaaccctg
    11641 tcactttata tccatctttt gcaaaggcaa ccgctaatgc tccagtaccg catgccagtt
    11701 ccaaaatatt ttttgtgtct tcttgtaaat gacgtttcga aaaagctaac cattgctgat
    11761 aaagtgtttc gtccatcact tcatcgtaaa tgaaagcaaa tgtttcataa gccatatgtt
    11821 aatccaacca ttcactaaga tcgactagcg gagcatctga ccatagtttt tccagattat
    11881 agaaatttcg ttctggcgca tggaaaacat gtacgatcac atctccaaga tcgatcaata
    11941 cccattttcc gccttctttt ccttcaatac gttttacttc atatttgttt tcttcttctt
    12001 tatcaatgat ttcttctgta attgcgttga tttgacgttc gctatttgct gaacagatca
    12061 tgaaataatc tgccaacaag gaaacatttc gaacgtctaa agcgataatg tcttctgccc
    12121 gttttgaatc tgctgcttca atcgcaattt ttaattgttc tttactatct atgatgattt
    12181 cctcctaata tgagcagctt atttttttgc tacccagtaa ttatatgttt cgattgtttt
    12241 tggataaatc tgttgttctt gcgcaagcaa atgggccaat gtatgttttg tttcaaatgc
    12301 tacagcttcg tctagatcag cccatgcaat ggctcgtgca tcttgtaccc caggaaaatc
    12361 tcgacctggt tcaatatagt ctgctacata aatgattttg tcaaggagac tcatcttagc
    12421 agccccagtc gtatgcaccc ggattgcatg aagaatctct gcatcggtga ttcctaattc
    12481 ccgctctaca aacgaagcgc caacaagacc atgccagatt gcattattat aattcaataa
    12541 ctccggatca aaaccgtctc ttacgattac cattttgaac tcctcatctg gtcgttcttt
    12601 tgcataatca tgtgtcaatg cagcaatact agctttttca ggagaagcac cgtatttttt
    12661 ggcaagagcc acggctgttt cttctactcc aagcacatgc ttgaagcgtt gttcgctcat
    12721 tctcatctgt attttttgca tcaggttttc tctagaataa gcagtatatt cattactata
    12781 gtccatattc atacaaccct tcattttgaa tataatcaat tactttatct ggaacaaggt
    12841 agcggataga acagccttct ttgatctttt gacgtatttt cgtggaactg atgtcgatct
    12901 caggtacatc tacccaaatt acaggatatg gagtatccgt tgtgtatcct ggtcgacgta
    12961 tacccacaaa gttgaccata gaagtcagct catcgatttt ataccatttt ggcaaatatt
    13021 ctaccatatc cccaccgata ataaagtaat aatctgtatc cggattgttt tgcgtcaatt
    13081 ccttcatagt atcataggtg taacttttcc caccacgagc taattcaatc gtttcaatct
    13141 gcaaaaaagg attgtcttcc accgctaatt ccaacatgtt gagtcgatgt tttgcatcaa
    13201 tcgtctgttt ctcatcaaca tgaggtggct gataagaagg catcaaaaat acgcggtcaa
    13261 gacctaaatt ccggccagct tgttcagcca tcactaaatg tgcaaggtga acgggattga
    13321 atgttccgcc caagatccct acttgctttt tcttctctaa gaattgaggc atttcttcag
    13381 gaaataattg tgaacgaaca aatgtcttag cttgcgtatt catcatggtc actccttata
    13441 ttgcttttac ttcttttgat agcctttgat acttttcttt tgtggaaggt ttgtataata
    13501 caataacacg tccaatgatt tggacgattt cgcaatctat ttctttttct aatacttgag
    13561 ctgcttcttc tgcaatctca tctgtatttt gaagtaacga tactttgatc agttctcttt
    13621 tttctaaagc ttcttcaatt tgaacgatca ttgctgaatt gatcccacct tttccgattt
    13681 gaaaaatcgg ctgaagatga tgcgctttgc tacgtaaaaa acgcttttgt tttcctctta
    13741 aactcataat tttccttctt ccttaaatca atgctttgcg tttcaataca tctacaccct
    13801 ttggcgccca gcccgcaatt actactggcg ctgttacagt gatccagcct agaccggcaa
    13861 aaacgatgtc tgttttttct ttcacagaaa actcaaaacg aacaagctcc ggaaatgcct
    13921 cgacttcatc aggacgagga ggctgtaata atccacctac atgtttttga taaaattcgt
    13981 ctgctttttc cagtttcgtt cgatgaatat ttacatcatt tgacacataa gcaataaatg
    14041 aagcacgatt gccgctgata aaatcaaatc ttgcaagtcc gcccaagaaa agtgtttgcc
    14101 cttcattcag ctgataaact ttaggtttga tttcttttaa cggtgcaatg atccgcaaat
    14161 cttttttacc taagtagtgc gccatttgat ggcgatggat aattcccggt gtatcaatca
    14221 aaaaatgccc gtcatctaaa ggaatctcga ttttatccaa ggtcgttcct ggaaactgcg
    14281 aagttgtgat tacatcttgt actcccgctg tatttttgat gatttgattg ataagcgtcg
    14341 attttccgac atttgttact ccgacgatat agacatcccg tccatcgcgg tattcttcga
    14401 ttttttctaa tagttccgtc atctcatgag atttcttagc actagttaat aatacatcta
    14461 ctggacgaat tcctgcttcg taagcacgtt ccttcatcca ttgtgttaat ttagtttttt
    14521 tcaatgattt aggtaatata tccactttgt tcccaactaa aagtactgga ttgtcaccga
    14581 caaaacggtg tagtcctggg attagtgaac cattgaagtc aaaaatatcc accacattga
    14641 cgatcaatgc atctttttgc cctaattcat tcagtaagcg caaaaagtcg tcatccgtca
    14701 atgagacatc ttgggtctca ttataatggc gtaatctgaa acaacgctga caatagactt
    14761 ccccggaagc taaacctttt tccaaagccg tttgcggcgt gtatcctaat tcaccgggtt
    14821 tgtttgtttg tataacggca ccacagccga tacattgtaa ttcttctgtc attcgattcc
    14881 acctcgccag cccatatcag ggtgttttgc taatagatag gccataattc ttttttccca
    14941 aaaacgatta aattgtgtct tccaactatc tgttgcgata atgggtttta caaggatgct
    15001 acgtatccct gcacgattgg ctccacgtat atcagtcata atctgatcgc ctaccattac
    15061 tatctcatca tctgctaaat ccaattgttt ctttgctatg ttgatccctc ttgctaaagg
    15121 tttcattgct cgtgcaacat acaaaagatc aaatttttca atcgctcgcg cgacacgttt
    15181 tgaattattg tttgaaacaa caacaacagg gattcctgca tttttcattt ctaaaatcca
    15241 agtaagcaac tcttctgttc catctggatt attccatgca atcaacgtat tgtctaaatc
    15301 ggtcaatact gctttgatgc ctagattctt taattgggca ggtgtaatct gatagatggc
    15361 ttctaccatc catgttggtt tgtaatttga aaacatgctg tctcctcatc tgcaaaaaat
    15421 gaaggagcac ataaagtact cctcaacccc gtattatact gcatatcagc aaaaaaaact
    15481 acctctatac tcgttcgtct ttcagaaaaa gcatttcttt acaaaatgac caaaaataaa
    15541 gattgatcac agaaaaattt agaaacaaaa aacaactaat attggcggaa cctcttgtat
    15601 cgtttttcca gtaatttatg ctgatctaat cgaacaagtt ccgtcaatct ttcaatcaac
    15661 gcttttttca taatgtgtgc gactttatat cgtggcaact gctcgccgtt gaacgtttca
    15721 ggaataactc gatcaacgat tcctaactcg cgtagttctg gcgcagtaat tttcatcaac
    15781 tcagctgctt ctgcggcgcg actaccgtct ttccacaaaa tcgacgcaaa tccttctgga
    15841 gaaagcacag cataaatcgt ttcttccagc atccagactt catccgctaa acctagagca
    15901 agggcaccgc cacttccacc ttcaccaatg atgatggcga tgatcggtac ctttaaatca
    15961 gacatttcga gcagatttct ggcaatagcc tctccttcgc cgcgctcttc tgctcctaca
    16021 ccgcaatatg cacctgctgt attgatcaag gtaatcaccg gtctattgaa cttttccgct
    16081 tgtttcatca gtcgtaaagc ttttcgatag ccttcaggat ggggagaacc aaaatttctg
    16141 cggatatttt cctgcagatc ccgtcctttt tgaataccga tcactgttac cggtttgcca
    16201 tctaatcgag cgattccacc aacaatcgct tcgtcatctg caaataaacg atcaccatgg
    16261 cattcctcga aagaatcgaa gatctcttca aaaaaatcca agcttgtcca tcgttcttta
    16321 gctcttgcta actgaacgac atcatgtgct gtcttatcca cgatctatcc atcctttctg
    16381 tgtatgcaat tcaagaagcg tatggatttt ctgtttcaat tccatgcggg gaacaatctg
    16441 atcgacaaaa ccatgagata ataagaattc agccttttgg aaatcttctg gaagttcctg
    16501 cttgatcgtc tgttcgatga cgcgtcttcc agcaaaaccg atcaagcttt ggggttctgc
    16561 tagaataata tcgccttcca ttgcaaaact ggcagttact cctccggtcg tcgggtccgt
    16621 taaaacagtt agataaaaaa gaccttcatt gctatgccgt ttgacagcag cagagatttt
    16681 tgccatctgc attagagaaa agattccttc ttgcatccgt gcgccacctg aagctgtgaa
    16741 caagacgact ggaagacttt cctttgttgc tcgttcgaat aatctggtga tcttttctcc
    16801 gacaatcgtt cccatacttc ccatgataaa attaggatcc atcactccaa taatgaaggg
    16861 aatcccctga atggttgctt taccagtgag gactgcttca tgaagtcctg ttttatcttg
    16921 cattttttta attttttccg tatattcggg aaatgctagc ggatctttgg ttacaagatc
    16981 cgtatcccat tcttcaaaac ttttttcatc aataatcaaa gctagacgct gccatgcacc
    17041 gattcgaaaa gcgtatccgc aatgagggca tactttttct tcaccgatgt ctttcgtata
    17101 aaggatatgt ttgcaatttg gacactttgc ccacatgtta tcaggaacag atggcgagtt
    17161 agcaggtttg ctctctctat taggattgat ccgaatatat ttctttttct taaacagagc
    17221 catctatgcg cctcctatct ccgtttctgg tgtccaattc ggtaaaaatt cttcttgtaa
    17281 aaatgctgtg ctgtaatcac ctgctatgac tgcaggatga ctaatcaaat ccatctgaaa
    17341 ttctgcgttc gtgatgattc cttctgtgat aaattcactt aaggctcgct gcatcttcat
    17401 taatgcttca aaacgcgtat ttccatggac gattattttt gcaatcattg aatcataata
    17461 tggcgggatc gtatatcccg ggtaaactgc actgtctact cgcagtccca tcccacctgc
    17521 tggaagcagt aagttttgga tcttccctgg agaaggagca aaatggaaag caggattttc
    17581 tgcattaatc cggcattcga ttgcgtgtcc ttggaatact acttcttctt gacacacatt
    17641 caaaggctca ccggctgcta tctccacctg tttttttact aaatcgattc ctgtgaccat
    17701 ttctgttact ggatgttcca cttggattcg agtattcatt tccatgaaat aaaaatcgcc
    17761 ttcttcatcc atcagaaact cgatcgttcc ggcattttca taattgactg ctttagctgc
    17821 tcgaacagca gcgtctccta gtgcttctct ttttgtttgt gagatcacta cagaaggaga
    17881 ttcttccagt actttttgat tgttgcgttg taaagaacaa tctcgctcgc ctaaatgaat
    17941 gacatgacca aatcgatcac ctaagatctg aacttctata tggcgagcag gataaatgat
    18001 tttttccaaa tacatatcat catttccaaa tgccgctgct gcttcttgct gagctgaaga
    18061 aaaatgctgt gggagctctt cttttgattg aactttccga atgcctttcc cgccaccacc
    18121 tgcagctgct ttcagcatca ctggataacc aattctgtct gctatttcca atgcttcttc
    18181 tactgtagat aatacaccag tacttcctgg aatgactggg acatttgctt cttgcatcaa
    18241 ttgacgcgca ttgatcttat ttcccattgc atcgatcgtt gcacttttag gaccaataaa
    18301 tgtgatattg cactcttcac acatggaggc aaatcggcta ttttcagata aaaaaccaaa
    18361 tcctggatga attgcttcgg cttttgtcac gattgcagcg ctcagtactt cctgaacatt
    18421 cagatatgaa tcaacggctt ttgccgggcc aatgcagatt gcttcatctg ctaactgtgt
    18481 atgaagtgct tcggcatctg cttctgaata tatcgctacg gtttggatcc ctagttcgcg
    18541 gcatgcacga atgatacgta cagcgatttc accgcggtta gctatcaata ctttagaaaa
    18601 catatttcac ctatccaatc ataaaggtta attccgcttc ggctactttt ttaccgtcta
    18661 ctttagcgat tcctttgcct attccggctg aagctttcac tttcaatatc tcaacttcaa
    18721 ggtataaggt atctcccggt gtaactttct tacggaattt tgctttgtcc aatccgccga
    18781 aataagccgt ctttcccttg aattgttcaa gagaaagtaa tgcaactgct cctgcttgag
    18841 ccattgcttc aacaatcaat acccctggca taacaggttc ttctggaaaa tgtccttgaa
    18901 aaaagggctc attgatcgtt acatttttct tagcaacgat ccgttctcct tcaaccattt
    18961 cttccactcg atcaatcaaa agcattggat aacgatgtgg aatgatttct tttatttctt
    19021 gtatgttcat tgttttccct ctttcctgct ttgcttattt ttgctgaatc ctaaagagtg
    19081 gctgtccata ttcgacaact gactcgtttt ctacaaggat ttctgtgatc actccgtcgg
    19141 cctcactagt tatctcattc atcagtttca tcgcttcaat aatgcagata acttctcctt
    19201 tggcaacttg atcacctact tttttgaaag ctggtttgtc gggcgctggt tgcagataaa
    19261 cgattcccac gattggcgaa acaacctcga ttccatcaaa tactgccgat tctttttctt
    19321 tcattatttc tggagcagtt gttgcttgtt caggtatgac attgactggc tccgaaactg
    19381 gcaacgtttc gtttgtttga accatattca tgcctcgact tgttttattt ttattcatat
    19441 acaattcaaa ttgaccttca cgcaaatcga attccgttag cgaggattga tcaaattgac
    19501 tgactaattc tctgatttca ttgatatcca aaattattcc tcccagcgtt tcatgcacag
    19561 aaccgcatta tgtccgccaa accctaatga attactcatt gcataagtaa aacttgcagg
    19621 tttgctttcg tttttgacaa ctgtcaagtc aatctcagga tcttgttttt ctacattgat
    19681 cgtaggtggg ataaattgat gttctaatgc cagcaaagtt gccaaggctt cgatcccgcc
    19741 ggctgctccc aataaatgtc cagtcatcga tttcgtgctg ctgacgtaag tatctctgaa
    19801 attttcacct aatgcgattt ggattgcttt tgcttctgcc tggtcattgg ctggtgtact
    19861 tgttccgtga gcattgatat atccgacttg ttccggctgt acaccagctt cttccatcgc
    19921 aagcttcatt gctttagatg caccagaacc atctggagta ggagctgtca tatggtaagc
    19981 gtcacagttt gcaccgtatc caacgatttc tccatagatt ttggcaccgc gagcttgtgc
    20041 atgttctaaa gattcaagaa ctagaacgcc tgctccttca cccatcacaa aaccattccg
    20101 attttcgtca aacggaatcg aaccacgatt aggatcagtt gattctgaga gtgctgttaa
    20161 agctgcaaat ccagcaatcc ccatctcaca aatcgttgct tctgttcctc cagcaagaat
    20221 gacatcagaa tagccatgtt tgatgttacg gaatgcttcc ccaattgaat tcgttccgct
    20281 agcacaagct gttacgatag ctgtacaaat accttttgca cctacacgca aagcaatatt
    20341 tccagctgcc atgttggcaa tcgccattgg tacgaacatt ggagaaactc gttttgcacc
    20401 tttttcatgt agacgaataa cttggttttc gattgttgga agaccaccga tcccagatcc
    20461 gatgatgacg ccaaaccggt cttgattcat tttttcttta tctaaaccgc tcatctccat
    20521 tgcttctaaa gcagcgtaga ttccatagat cgaaaacata tccattcgtt tgctatcttt
    20581 tttaataaaa tatttatcgt aagggaaatc tttgacttca cccgctaagg taatccctgt
    20641 ttctgaagca tcaaatttag tgatcggtgc gatgccattc gtcccctctt ttaagctatt
    20701 caaaaagctg tctgcgtcat ttccaatagg tgaagtgact ccatagccag taattaccac
    20761 tcgattcatt tgtttgctct ccttttctta tccgtgcatg accaatccgc catcgacatt
    20821 gatgacttgt ccggtgatat atggattttg tgctaagaaa actgctgttt gtgcaatatc
    20881 ttctacttgt ccgaaacgct gcatcggaat ttgcttttcc gcttgttcct tgactttgtc
    20941 tgctaaaact tccgtcatat cagttgtgat gaatcctggc gcaatggcat tacatgtaat
    21001 gcctctagtt gcagcttctc gtgccacaga ttttgttaat cctactacgc cagctttact
    21061 agctgcataa tttgcttgac caatatttcc aatcaaccca gatacactag agagattaat
    21121 gatggcccct tctcgctgct tcatcatttt tttcaatacg tgctgcgtca tattgaaggt
    21181 tccaatcaaa ttgatatcca gacatttttt gaaatcttct gcatccattc gcatcacaag
    21241 tttgtcattt gtgattccgg cattgtttac taacacatgg atcgatccaa gcttttcttc
    21301 tgcttctttg atcatttgtc ccgctttctc ataatcagag atgtcaccgg aaactcctac
    21361 gcattttaca ccgaatgctt cgatttcttc tatcttttct tttggaatct ctccgcgacc
    21421 attcaaaatg atatttgctc cagcttttgc aaaagctaag gccatcgctt tgccgattcc
    21481 tcttgtacta cctgtgataa atacattttt tccttttaca tccataacgt tcctccttat
    21541 agtattgcta ttgtttcatc aaatgtctgc ttattctcaa cacgcagaac tggtattgtt
    21601 ttatcgattt ttttcataaa tccgcttaat acttttccgg ggccgacttc gatgacttgt
    21661 tcgatgccga ttgtttttaa cttatggata ctctcataga aacgaacagg ttgcatgact
    21721 tgctgttcaa gtagtcccgc gattgtttct ttcttcatta tttccgttgt tgtgttgctt
    21781 atgataggaa aagaaggttc agagaattga atctgactta ggtccttcgc cagttttttt
    21841 gctgccggtt ctaaaatagc tgtatgaaaa ggcccgctga catttagagg gatcattctt
    21901 ttgaaccctt tttcttttaa tagtaaaaca gcttcgtcta ctgctttttc ttcgccacca
    21961 atcacgatct gctgaggtgt attataattt gcaggagata cgatgccgta cttgctagct
    22021 tcatgacagc tttcctcgat cgtttcaatc ggcgcattca tcactgcaac cattttcccg
    22081 cttccagctg gggcagcttc tgtcatataa gcgcctcttt ttgctactaa cgcaactgct
    22141 tcagtgaagg atagcgcatt actagctact aatgccgaat attctcctaa actcagtcct
    22201 aaagctgcat ctgggatgat tccatgctcc ttcaataagc gataatacgc gatgctgact
    22261 gttagaatag ctggctgtgt atattgcgtc tgatccaaac gttcattttc tgtaaagcaa
    22321 agttcagcca tatcgtagcc gagaatctca cttgcttcat caaatgtctg ctttacaacg
    22381 gcttcttcat ataaatcttt tcccatacct tgatattgtg caccttggcc actaaataag
    22441 aatgctgttt tcatgttttt ctccaatata tccagaatat atgtttgatt cttcctattc
    22501 aaaaaggccg agacattcct atttcaggaa atgtcccagc ccccaaccta attttaatga
    22561 ttatgcagtt tgtttttcta cgtaagtcac taaatcttga accgttttga ttccgtcttc
    22621 tgtttcgatt ttcacgtcaa attcatcttc aatttcattg atgatttgga ataaatccaa
    22681 gctgtcagct tctaagtctt cttggatgtc agtagtcaat ttgatttctt cagtttcttt
    22741 tcctaattct tctgcgatga tttcttgaat tttttcgaat accataataa tatattcctc
    22801 cgatattgtt tgctttttat ttttataatt taacagtcta caactccatg agaatacttc
    22861 cccatgttaa acctccgcca tagcctgtaa atattacttt ctgctgtttt cctaaggtga
    22921 tctttccact agaaactgct tcatccaata agatagggat gcttgcagca gatgtattcc
    22981 catatttatc catattggtc aggaactttt cttgcggcat ctttactttt cgggcaattt
    23041 tctcaataat tctgaggttt gcctgatgca aaagcagata atcaactggt ttgtctttca
    23101 tgacttcttg gatattgttt gcaacgtctc gtacggcaaa atcaaaaata tctctgccag
    23161 tcatttgcaa ataatacgaa ccttctgaat cttctgaata gaacggattt ttattttgct
    23221 ggtagccagc ggtcaatgag ctacttctgg taccgtcagc tgctaatttt tctttcagca
    23281 attttttctg tggattcgct tctaagagaa tcccacctgc tccatcgcca aacaacacag
    23341 cagtcgtacg atcagaccaa tcgattagct tagatagtgt ttcaccacca atcaccagtc
    23401 ccttagttga gccgcagcgg atcatttttt cagccatgct taacgcataa acaaatcctg
    23461 agcacgcagc actgatatca aaagcgatag catgagttgc tcccaatttc ccttgtactt
    23521 gtgctgctac agatggtgtc gtgtaatcgg gcgacattgt tgctactaaa ataaaatcca
    23581 aatctttagg gtttagattt ttctgtttta tcaatttttc cgccactaaa atgcataaat
    23641 cagaagtctc ctgatttgtt acacatcttc gttcacgaat acccgtcctt gacgaaatcc
    23701 attcatcaga ggtatccatc atcttggaaa gatcattatt agtaataatc ttttcaggaa
    23761 ggacgctggc tgttgcagta atcattccaa attgttccat taaatatcct cacttatagt
    23821 cttgcaagaa gtcgtgcaag tttttcagtg catccagcaa ggcatgctgt tcctccgtag
    23881 ccattccgtc taagatgttc ttgaccattt cacgatgaaa atgctgatgg acccgaaata
    23941 gtaactttcc ttttttcgtt agtcccaact ttacaacgcg gcggtcatct tcactgcgga
    24001 tacgttcgac atagcctttt tttactaact tgttaatagc agtggtcaag gtcccaacag
    24061 taattgatag ttctttggct acttctgaag ttgttttttt cttgtacatc ccgattgcct
    24121 cgatcgtgtg catctctgtg attgacagat ctttgaattg agattttttc agctcagact
    24181 cttcgattgt caaaatatca ttgaagacac taacaagata atcatttact gtttttaaat
    24241 ctggttccat gttccaccgt ccactaatta gtttgattat caaatctttt gatgttcaaa
    24301 ctatatctta acttttttca aaatgcaacc ttaaaagatc atttttttac tatatgagct
    24361 ttttttaaga ttttactcat ttaaaacaac tgataaatca gcatttataa tttcttttat
    24421 tagaaaaatc atctatctca catattttga ttatcaaagt attttctgtg aacagaacta
    24481 tagaattccc taaaacttgt ccattatttc aaaatttgtt atagtctttt tattcaaagc
    24541 gtaaaaggag atcctatgtt aaaagaaaaa atgaaaactc tccccatgct gccgggtgtc
    24601 tatcttatga aagaccgaga tggtaaggtc atctatgttg gtaaagcaaa acggctcaaa
    24661 aatagagtaa gcagctattt tcatcagaat aaacagcatt caaaaaaagt attacgtatg
    24721 attcatcata taacagattt tgatttcgtc gtagtagaca cggaattaga tgctttattg
    24781 ctcgagtgtc aattgatcca acattaccgt cctttttata accgacaaat gaattatttc
    24841 agtaattata attatgtaca tattaccaat aagggatttg tattaacaga tactcctacg
    24901 gctcgaacat acgggccttt tcgtctctat aaaaaaatgc cgtctatttt gcgtataatg
    24961 gaagaaactt atcaaatgcc ttggttgtct gaaattagtt tgttagcttt gcgagtccag
    25021 cttcctgacc tacaggaaat gacttttgaa cagaaaaaaa aggaactcca agggctgttt
    25081 caaggccgaa ataaaaagct actgacttac ttgaaaaaaa gacaacaaca tttcatctat
    25141 cagttgaatt tcgaaaaagc cggtatgctt caaaaagata tcgaattagt tacttatttt
    25201 attagacgga tccaggaaca aaagcagttt ttaagaacac catcgctcac cttcagcatg
    25261 ccattagcag cagatgagag tcagaaaaag cactacctcg tttgttatgg tcaacttgca
    25321 gaaacaatga ttacctctgg tgacgtttct cctgacttct attatgaaaa gaaagaagct
    25381 catttatctt tgaaacgtca attgtcaaaa gaagaaatcg atcctgtaca aatcttgatc
    25441 agttaccgca aaaaattaga aaaagaacag tttgaaattg aactgttaaa caaaaaagaa
    25501 gctgaaaagc aactaaatta gttgcttctc ggcttctttt aggcatcttc aacttcaaat
    25561 gtcaattatc ctaaaattta ttggattaag tcatagattt ccatcgctac gatatcgata
    25621 ttatcaaatt cgtattgctg atgagtatct gtttcagtta attcaaatgt atcggtcgct
    25681 ttatcataag ttactgtaca cttctctacg ccttcttttt caaaacggcg aacttgcagt
    25741 tcattatctg ctgactcgac catagcctcc agtcgtttta tgattgcgac taattgtgaa
    25801 tgtgtcatcg gaggtcctcc ttttcttatt tctgttatat tgtatcaaaa gcatagccta
    25861 cttgcattga ttttctctaa aaaaactcgt tttttatgat tttttttctg gtatttttcc
    25921 ttcaggccac caaagtttga tcaaagcttg ggttccgtca ttctcaaaac ctttatctgc
    25981 caactcttca tatagtttca atgcttgggt agttgctggc aatacaagat ccattttttc
    26041 tgcttcttct aatgcaatct ttaaatcttt gataaaatgt ttgacaaaaa aaccaggtgt
    26101 gtaatcttct tttaaaatac gaggagaata attgcttaaa gaccagttag ctgcacttcc
    26161 acctgaaagc gtctcaatca ctttctttaa atcaagtccg tttttttgtg catagacaag
    26221 catttccgtc attcctgtca tcgtacctgc aatcatgatc tgattagcca tttttgtatg
    26281 ctgacctttc ccagcagaac catgcaatgt aaatgtcgta ccaaattctt tgaataaagg
    26341 cagtacttga tcataaacgg cttcttctcc accgaccatg atcgtcagtg taccattctt
    26401 tgctcctaag tcaccaccgg ataccggtgc atctaacgca tctgcgcctt tttcttttgc
    26461 tgtttttgca attttttctg ccaggcttgg tgtacttgta gtcaaatcaa ctaaaatatg
    26521 tcctgagata tctgcagaaa aaatccccga ctgtccatag tagatttctt ctacatcttt
    26581 ggggtaacct accattgtaa agagaatatt actttgttct gctaccgctt ttggtgtatc
    26641 tgcccagata gctccttctg ttactaaagg atcagctttt gcttttgtcc gattatagac
    26701 agctacttcg tgtcctgctt ctagtagatg gcgtgcgaca gcacttccca tgacgcctgt
    26761 tccgataaaa ccaagtttca ttttttcgac ctcctaaaaa tcaaaaatcc ttgcttctat
    26821 gctagtatac gctagaaaca aggatttttt cataaaaaat gtttgaattt tatcttttaa
    26881 atgaatttaa ttttattttg attcgttcaa tcgagtcttc ttcttctttt cttcgcatct
    26941 cttcttcatg ataaacaacc atgtcttgat aaaattcgat catagcttcg ccgaaatgtg
    27001 tagatgaaat atcataaagt ttagcttcta aaacttttgg atctttagga acttcactgg
    27061 aaatataatc aataagtgct ggtgcaaagt cttcgtcggt ttcaaaagtt ttccctaatg
    27121 aaggatgatc gaacaatcgg ttcaaataag catttccttc cacgacacaa ggtgttccgg
    27181 ctgccatcgc ttctgtataa gtaagccctt gtgtttctga agtagaagca ctgacaaaat
    27241 aatctgccgc tttataataa agtgctacat cattgttgtc cacttctcct gtgaactgca
    27301 caaattcttc taactgcagt tctgagatca attcctctaa ctcttctaca taaggtcctt
    27361 ttcctacgat aactaatctg gcgttaggat aagcggagat gacctgagga aacccattaa
    27421 tcaaggcttg gatatttttc tcataagaaa tcctgcttaa agaaagaatc atcaaatggt
    27481 tttcctgaag acctagtgac tcccttaatt tgctgatatc ctgctgagtg atatcagaac
    27541 gtttgaattt ttcaatgtcg ataccagtag gaatcacgcg aagcggtgct attacaccat
    27601 agctgcgtaa tgtatcaata acacgttcac ttggacaaac tacacctgtc gtatgatttg
    27661 caaataatct agacaagtat tttacatggg attgcctgat cacttttcct ttaccgatat
    27721 aatgaaggta gtcttcatac atcgtatggt aagtatggat cagaggtatt ttcaacttct
    27781 tagctaccat cttcccaagt atccctgctc cgaattctgt atgggtatga ataagatcta
    27841 gttctagttc tttggcaacc aaataagcat accacatgcc tctaacaaca actcttcgat
    27901 ccttgaaaga aataaatggt acacttggca ttcgaatcac atctttttcc aacttatccg
    27961 cattaggatc ggtcgttgta aaaatataga cttcatgccc atgtctttct aattcttgtt
    28021 ttaatgtttt gatcgatgta gcaactccgc tgacttgcgg aaagtaggta tcggtaaaaa
    28081 agccgatttt catgtttttc gcctccaaac tagtccttga cctgatttac tttttttaat
    28141 ttgctagaga ctttttcatt cagtacactt tcgtatacat ttttaagttc ttcaccgatt
    28201 ttattgatac ttcgctcttt tgctgtttga taaccggctt gtgtcgtact cggtagttct
    28261 tgattggtaa tctgttggat cagtcggata aattcttcgt ttgtcttccc catatagcag
    28321 ttcttgctat cttctaacca gccattatac actggaatat ctcgaacaag tacgttttgt
    28381 ttgcttgcta aagcttctaa aacaacgatc ccttctgtct cttcataaga agggaaaaag
    28441 aatagatctg cacctgaata cgcaccttct atgatctctc cacgaatgta accaggaaac
    28501 aggacatttt caggatgatc ttcttttaca attttccgga tgttccgagg aatcgagtac
    28561 atgggaacat gaccaaacca aataaatgtg tattcgggca tcttcttagc aatttctacg
    28621 aaatcaatga ttcctttacg ttcgaaaaac aaaccgacac aaatgattac tttttgatcc
    28681 ggagacagtt tgaaatattc tctgaacttt tgttctttca ttggatcagg gtgatatttc
    28741 tctaagtcga tcccattgga aatagcttga atcggcacac ggataccata gctttccaac
    28801 aactgttttg aataaggtgt tggcgtgatc agatagtccg ctttttggta caatcctacc
    28861 agatattttt ttacgatagg agaaagctgg ttcgatctga taaaggaatt tcggaaatct
    28921 tcctctgtag aatgcgcatg atagacaact ttttttcctt ctcttctggc tttattgacc
    28981 atattatgac tattgattcc gtatgtattg atgtgcagga tgtcataatc ttctttttca
    29041 tctagtgtat aagagatacc gacttccgtc agagcacgtt tttgatgatc aagcgcacgc
    29101 ccgattccag attttgcaag catcttttca ctttcaaaat ataataatac cttcacctta
    29161 cgtccccctt cacttatata gtataacata gcctacaaac tgtcactcaa acttaagccc
    29221 tatttttgtc tattcttact gacaaaaacg ttttcttaaa aaagaacaaa aaaactggcg
    29281 tagctctttt acaagccaca ccagcttttg atacgttgtt tattttacat attcatgaac
    29341 aagttcaacg acttcttcca tcatatcgca ttctttcaat gcacgatcag caagttcagc
    29401 cattttcgct gtgtccaagc gtttcattaa actacgcgtt ttaagaatag atgtcgcact
    29461 cattgagaac tcatctagac ccatacctac tagcaatgga acagctgttt gatctccagc
    29521 catttctcca cacatacctg cccattttcc ttcagcgtgt gctgcatcaa ttacattttt
    29581 gatcaaacgt aaaattgatg ggttatatgg ttggtacaag taagaaacgc gttcgttcat
    29641 acggtctgct gccattgtgt attgaatcaa atcgttcgta cctacagaga agaaatctac
    29701 ttcttttgca aacttgtctg ctaagactgc tgctgctgga atctcgatca tgatgccgac
    29761 ttggatcgta tcagatactt ccttgccttc acttatcaat ttttgttttt cttcttcaaa
    29821 gatcgctttt gctgcgcgga attctttgag tgtagctacc atagggaaca tgatacgtaa
    29881 attaccatga acagatgcac gaagcaatgc acgcatttgt gtacggaaca tttcgtcgcc
    29941 ttgttcagat aaactgatac gcaatgcacg atatcctaag aatggattca tttcatgagg
    30001 taattgcaga tatggtagtt ctttatctcc accgatgtcc attgtacgaa caactacagg
    30061 ttttccttcc ataccttcta atacagcttt gtaagcttca tattggtcat cttctgttgg
    30121 gaagtctgga gaatccatat acaggaattc agtacggtac agaccaactg cttctccacc
    30181 attattatgg acaccaacta gatcttttgg tgttccgatg tttgcagcta attcaaaatg
    30241 cttgccgtca gctgtgacag tttctgcatt ttttaatttt tcccattctg ctttttgtgc
    30301 tgcgtaatct gcacctgctt tttcaaattc agctttttgt tcatctgtag gatcgatgat
    30361 tacatcgcct tcgatcccgt tgacagccaa aatatcgcct tctttgactt tagcagtaat
    30421 ttcttttgtc ccaacgattg ctggaatttc taaagaacgt gccatgatag cagaatgtga
    30481 agtacgtcca ccaatgtctg ttacaaacgc ttttacaaaa ttgcgatcta attgtgctgt
    30541 atcacttgga gtcaagtcat gtgcaacaac gaccacttct tcgttgatca ttgatggatt
    30601 tggtaaagta acgcctaata agtgcgctaa aatacgttta gcaacgtcac gaatatctgc
    30661 agcacgctct tgcatataag cattatcttc cattgcttcg aacataccga tatacatatc
    30721 cgttacttct tttagcgctg attcagcatt tacgctgttg tctttaatat tttgcttgat
    30781 ttgacctacc atttctggat ctgaaagaac catcaaatgg gcatcaaata cttgcgcttc
    30841 tgcttcacct aagctttgcg ctgctttttc acgaatttgc tgcaattctt cagtagattt
    30901 agctaatgca gcatccaaac gagcttcttc agccgcagta tcttctactg ttgccttact
    30961 gaatgttaaa tccggttgaa ctagcaggta agcttttgca acggctacac cgtcactagc
    31021 ggcaatccct tttagcattt caaccattat tcagataagc cttctttctt cattgtttca
    31081 acgattgctg ccattgcatc agcttcgtca gcaccttctg cagtaatagt aacatcagaa
    31141 ccttgaccta cacctaaaga cataacgccc atgattgatt tcaagtttac tgatttacct
    31201 ttatactcta agtttacatc agagttaaat ttgcttgctg tttgtactaa tagtgtagct
    31261 ggacgagcgt ggatcccagt ttctgctact acgtgaaatt ctttcttttc catattaatc
    31321 ggtctccttt aagtgagtgt tgtttttatg tgagggtttt cttttttagt aattcagaga
    31381 atcctaacaa atgccaccct ttcatctgta aagattaaca ttttttttcg ttagatacaa
    31441 cagttttcat tcaatttcag ataaaagtat tcaaattatt ccggattctt tttcatcctt
    31501 ttcttcacat tttataacaa acgtgtttat ttcctttttc ttgtcgcttt ctcttctcct
    31561 gacgtttatc attctttcct ttgaccctct ttgttttcat atgaaacgaa ttacttgctt
    31621 ccctttttat ttttagtata ataagagtca aaggtcagga atggtcaata gagatttcac
    31681 cttttctacc tcataaatct cttaaaaaac taggggttat tcttttacct catgaaaaac
    31741 gagatgtaaa atatggatgt acccattttt gtgaaaggac gtgaatgatt catgctttgt
    31801 caaaactgcg gcaagaatga ggcaacgatt cacttgtatg ccactgtcaa tggtcagcgg
    31861 acacaactcg attactgtca gagctgttat caaaaaatca aaaatcaaca aaatggaggt
    31921 ctgactaata tggcccaaaa tgatccattt ggatttggca gtttggacga tcttttccgt
    31981 tccatgtctc gccaaatgca acagcaagga aattatgagc aaacaccacc aacacaattt
    32041 ggcggaaaca acaacttcaa tggtggtcag ccacctcaag gcaatacaga aggtttattg
    32101 ggagaatacg gaatcaatat cacagaacaa gcacgacaag gtgatatcga tcctgtgatc
    32161 ggacgcgatg acgaaatcaa acgagtcatt gaaattttaa atcgccgaac caagaacaat
    32221 cctgtcttga ttggagaacc aggtgttggt aaaacagcag ttgttgaagg tttagcacaa
    32281 aaaatcgtag atggtgatgt accgcaaaaa ttaatggaca aagaagtcat tcgtttagat
    32341 gtcgtatctt tagtccaagg tactggtata cgaggacaat ttgaagaacg tatgcaaaaa
    32401 ttgattgaag agatccgtca agcagaaaat gtgatcctat tcatagatga agttcacgaa
    32461 atcgtcggtg ctggttctgc tggtgatgga aatatggatg ctggtaatat tttaaaacca
    32521 gctttagctc gaggagaatt gcaaatggtt ggtgctacta ccttaaatga gtaccgcatc
    32581 atcgaaaaag acgctgcttt agaacgtcgt atgcaacctg tacgggtaga tgaaccaact
    32641 gtcgaagaaa cgatcagtat tttgaaaggt ttgcaaaaac gttatgaaga ctatcatcat
    32701 gtaaaatata ctgatgaggc catcgaagca gccgcaactt tatccaatcg ttacgtccaa
    32761 gatcgcttct tgccggataa agccatcgat ttgctagatg aaacaggttc taagaaaaac
    32821 ttgacgatcc aaatcgttga tcctaaaaca atcgagaaaa aactgcaaga agcagaagaa
    32881 caaaaagttt tagcttctcg agaagaagat ttcgaaaaag cagcttatta tcgcgatcag
    32941 atcaataaac ttcaaaaaat gaaagaacgt cagctcactg aagaggaaac acctgtgatt
    33001 accgaaaaag atatggaaaa aatcgttgaa caacggacag gtattccagt gggtgaatta
    33061 aaagaaaaag aacagacaca actgaaaaac ttagcagatg acttgaaagc tcatgtcatc
    33121 ggacaagata acgctgtaga tcgagtagcg aaagcgattc gccgaaaccg tgttggatta
    33181 aacaaacaga atcgtccaat cggctccttc ttatttgttg gaccaactgg tgtaggtaaa
    33241 acagagcttg cgaaacaact tgcctacgaa ctattcggtt cacaagattc aatgattcgt
    33301 ttcgatatgt ctgaatatat ggaaaaacat agtgtctcta aattgattgg ttctcctcca
    33361 ggttatgtcg gatacgaaga agctggtcaa ttaacagaaa aagtacggag aaatccttac
    33421 agtcttgtct tgttagatga agtagaaaaa gctcatccag atgttttgca tatgttcttg
    33481 caaatcttag atgatggtcg attgacagat gcacaaggaa gaacggtcag ctttaaagat
    33541 acgatcatca ttatgacaag taatgccgga actggtaaag tagaagcaaa cgttggtttt
    33601 ggtgcggcac gcgaaggtgt tactcgttct gtattgaacc aattaaacaa ctactttaca
    33661 ccagaatttc tgaaccgttt tgacgggatc atcgaattca gtgcattatc aaaagaaaac
    33721 ttgatgacaa tcgtcacact aatgctagac gatgtcaacc aaatgctggc agcacagcaa
    33781 cttcacatcg aagttcctac gaatgtcaaa gaaaaattag ttgacttagg ctatgatcca
    33841 tctatgggtg ctcgtcctct tcgacgcacg atccaagaac aaatcgaaga tggtatcgct
    33901 gaattttatc ttgatcaccc ttctatccat gagttgaaag caaaactgga taaagatgga
    33961 aaaatcatcg ttacttctaa accagaacgt ttggctaaag aatcagccga agaaacggct
    34021 gaataaatcc agttttatag cgtgagacgg tatttctttg agaaatgccg tctcattctt
    34081 ttttcagaaa agtcaaaata ctgttcattt tataaaaaag aaattataat aagagaaaca
    34141 agcaattaaa aatacataaa agaggtgagc gccatgaaat tggtaaatgt aacaaacagc
    34201 cattcccgtc ttgtattaaa ccagcttgaa aacactgatg cccatctagt caaggtctac
    34261 acagccggaa ataccactat tgtctacact gaagcccctg aacataatga aattctgctg
    34321 atcaatgaca aacgtaaaat ccagccgaaa gaaatcgaag atgctaaaaa ttatttctta
    34381 gataaaatca aagacgccgt ttaccacgag gatgaaatca aagtaatcga attggcaggc
    34441 cttgttgaaa tctcgattcc aaaacatgaa ttaggcgcta cattagccgt gtaaacaaat
    34501 tttgaacata ataattaaag agcgtgggac aaaagtaaag aacacttttg tctcacgctc
    34561 taaacacgta taaacggcga aagcagaagc aactccttcg gaaataagct gaaattcacg
    34621 aaaattgctt ttcaaatttt tgtgaattcc agcttatttc ttggagttaa acgcttctgt
    34681 ctcagcctct ttttctttct agctttttga tttttctctt ttcttttgta cttttctctt
    34741 ttcattttca gttctacgcg tgtctttatt tttaactttt tcctctttat ggatgattga
    34801 tcgtactttt tgtgcaattt gctcgttttt gtcccagtct tttacatcta ataatcgaca
    34861 taatcgtaac atctcttctt ttttctgttt ttttctttca cgtctttgcc attctgtttc
    34921 catgtgtcac actctccttt ctttaatcat atgtacgcaa aataattttt atattttttt
    34981 gattagacat ttctatgatt ttaatatagt aaaaagagcc gtcacggaaa atccgtcacg
    35041 gctctaaaca aaatatgaga ggctgttttt gtttggctat tcttattact tgatgcaggg
    35101 cagcttgtgt caagacttct ttacatcaaa ctttttaatt ttacattggg atatttatcc
    35161 gcaaaccagc gttctgcaaa ttggttctcg aataagaaca acggttggtc gaaacggtca
    35221 cgagccaaga tattgcgact tgaactcatc ttctcatcca aatcttctgg atcgatccag
    35281 cgagcgattt tgtgtcccat tggagacatg attacttcgg cgttatactc atttaacata
    35341 cgatattgga atacttcgaa ttgtagctga ccaacagctc caatgatata ttcttccgtt
    35401 agatatgttt tataaagctg aatcgctcct tcttgaacta attgatagat tcctttgtgg
    35461 aaggattttt gtttcatgac attttttgca gtcactttca taaacagctc tggagtaaat
    35521 gaagggagtt cttcataagc aacttttagt tttccttcga acaatgtatc cccaatctga
    35581 taattgcctg tatcatatac accgatgata tcgcctgcta ctgctttttc gacgttttct
    35641 ctcgaatctg ccataaattg tgtgacattg cttaatttca gttttttatt tgtacgttcc
    35701 aaccagacat ccattcctcg ttcgaatgtt ccagaacaga ttcggacaaa agcgattcgg
    35761 tcacgatggg ctggattcat atttgcttgg atcttgaata cgaaacctga aaattcttcc
    35821 tcataaggac ttaccatctg atcatcttgt gttttgtgtc cataaggagc tggtgccaat
    35881 tcaacgaaag tctctaaaaa agtctgtaca ccgaagttag tcaatgcaga accaaaaaat
    35941 actggtgtct gatcgccacg agcaattttt tcttgattaa atgcatctcc agcctctttg
    36001 attagttcta cttcttctaa gacttgttca tataaggaat tttcagttag aggatgattt
    36061 tcgggaagca gtccatcttc atccaattct actaatcgtt catcctgata attttccgga
    36121 cgataaaact ctacacgatt atggtagata tcataaagac cttctagccc tttacccata
    36181 ccgattggcc aattcatcgg ataagattcg atatctaata gctcttctaa ttcttctaac
    36241 aattccaatg gttcacgacc atcacgatct agtttgttga taaaagtaaa tatcgggatg
    36301 ccacgttttt ttacaacttg gaataatttc tttgtctgtg cttcgatccc ttttgcacta
    36361 tcgattacca tgaccgcact atccacggcc atcaaagtac gataagtatc ttcagaaaaa
    36421 tcttcatgtc ctggtgtatc caagatattt actcgtttcc cttgataatc aaactgcata
    36481 acagaactag taacagaaat cccacgttgt ttctcgattt ccatccagtc tgatttggca
    36541 aaattacctg tttttttgcc ttttacggtc ccggcttgac ggatagcccc accaaacaat
    36601 agtaattgtt ctgtaatcgt tgttttccca gcatccggat gggaaatgat cgcaaaagtt
    36661 ctgcgattgt ccacttgttg ctttaatttt ggattattca taacctaact ccatttcttc
    36721 cattcaatta tttatatttt ctctaggcac agattgtccg atctcttaaa gaaagacaat
    36781 ttcatatagg gctgtgacaa aagccgtgta gcagtctctt tttccgagta aacggcgttc
    36841 tagagacagc ctatcagcaa taagcccacc caagccaaaa atacgaaaag ctgtttttgc
    36901 ttggctgctc ttattactta atgcaggata gctttttcac aacctttgtc aactactaca
    36961 actgaatcag tatagcatgg attcagcgaa tgaaaaagcc accaaaccat aagagtcaaa
    37021 tatttttttg tcagctgact aaaagaaaag acgtgttgct tgtttattca agcaacacgt
    37081 ctttcataac caagtttcca attatcttct tggctcgtca tcttcgaatt cttttctgaa
    37141 gtatcttcgt tcttcttcag gttccgcttc tgtttcttcc ggatcatgaa aaatgacacg
    37201 gattttaagg attcgagaac cttccatttc ttcagaaacc agcgtaatat tatcgacatc
    37261 aaacgataac ttttcgcctt catccggaat catgcctaat gctgtaatca aataaccagc
    37321 catcgtatct acatcactca tatgcagatc actgtcaaaa gcttcattga actcatcaat
    37381 cagcatacgt ccttggatga tatattcgtg ttcatcgatt ttttcataaa gattctcaac
    37441 ttcatctgat tcatcatcga tttctccgac gatttcttct aaaaggtctt ctagtgttgc
    37501 taacccaacg acgccgccat attcatctaa taaaatagcc atctgattct gcgtcttttt
    37561 catttcatat aacagatcat caataaagac cgtttcagga acgaataaag gctcctgcat
    37621 gattttcttg atatctaaat tatcaaagcc gaatttatgg gcagctttta gtaaattctt
    37681 tgtatgaagg attccgacta ctttatcttt gtcttcgtta taaacaggga ttcttgaata
    37741 gttttcggat aaaacttcat tcacattttc ttccacagtg tcgttgatat caatcataaa
    37801 tgcatccgtt cgtgggacca tgacttctcg ggcaactttc gtatcaagag aaaaaacccc
    37861 ttggagcatt tctaattctt cattattcaa tacgccttcg ttttcaagca tataacgcat
    37921 ttcatctctg gtcatttttg aatcttcatc atcaaaagtc atcggcgtga tacgcgccaa
    37981 taaacttgtg gaagcagaaa gcagccagac gaagggctta gctactacac caatcaagcg
    38041 tatcagccct gaagtgaact ttgcgacttc ttctgattta tttaaagcaa tacgtttagg
    38101 gtacaattct ccaaaaacaa tcgatacata ggtcaaaata gccagcacaa tgatatttgc
    38161 aatatttttt gccgctgtgc cgccacctaa taccggagct aaccgttccg ataaagtatt
    38221 agctagtgaa gcaccagaca aaatgttgac caaagtgatt cctacttgga ttgtcgatag
    38281 gaaattattt ggattctgca atatttttaa aagcttttga gatttcacat ctccttcatc
    38341 agctttttgc tcgattcgat tcttattgat cgaaacaaca gcaatttcgg aagctgctaa
    38401 aaaagcattg atcaatgtca aaacgatcaa taataaaatc tgcgctaaca gcgactgact
    38461 ctcagggtca gcattcataa tcgcattctc tccttataaa attaattttt agtttacgat
    38521 agaaaaaaac gtggcactat agccacgtta aaatggtatc acaaagcaat tttctttgca
    38581 ataaaaacaa gtgtactaaa actacctacg aggtcgtagc aattttcttc ttgttttcat
    38641 tttgcttgtc ttctttgacg attttgatta tataggaaat gatcgtcttg cagattgcgt
    38701 aaaaaggaac acctaagaag ataccaagca atccggcaat atttccagct actagaagaa
    38761 cgataatgat cgttaatgga tggattttca gtgatttccc aattacatta ggataaatga
    38821 tattcccatc caactgttgg acgattagca caaccacaca acaaagtaat gcttttaccg
    38881 gatcattgaa gactgttact agaaatgcag gtgctagtcc tagataaggt cctaaatatg
    38941 gaattaggtt tgtcaatccc gcaatgaccc caaataagaa agcataatcc acaccaatta
    39001 ccatatatcc taaaaatgtg aaggtaccaa cgaataaaca ttcgattgct tgtccgctaa
    39061 tgtaattagc caatgtttta ttcagttgcc ccaataactc cacaatttgg tttcttcttt
    39121 tttctgggaa aaactgttgg atgtttggca ctagtttttc tccgtctttc aacatataga
    39181 acaagatgaa tggtgctgta atgattacta cggttgccga agcgatcgtt ccaacgatcg
    39241 aacctaaact attggatact ccactaagga attgctgaat gattgtcccg taagaaatgt
    39301 ctaattgctc aaaatattta ttgatatcta cttccttgaa caaaggcaat tcggctacct
    39361 cttttaacca gctttctacc tgtttgatga aatcaggcat attagatgcc aatgaggaaa
    39421 tttgctgtac tagacttggg atgacactaa gtaaaatcca aataattgct gcaactaaaa
    39481 ggagcagcac aattgcgaca gcccatattc ttttgatttt tgctttcatc aacagcttga
    39541 caataggatt caataaatag taaagaaagc ctgcaatcag tacaggtgca aataacgtgg
    39601 aaaaaaatgt cccgatcggt tcgaaaataa agtttatttc tgatgaaatc atgatcaatg
    39661 cagctatgat caataattca agcgaccaaa acattagttt agactgtcta agtttttcaa
    39721 acaatagatt tcctcctttc tttcttacta gtatatatta tattcgttaa aaattctttt
    39781 attctttttt tatttttgaa aacttgccat actttttatt tgttttattt tccagtatac
    39841 tatacgaaag gaaggtggct agaccatgaa agttgtacaa acaaaagata caatgagcaa
    39901 tatttactta gatgctgtac ggatcaggca tcaagttttt gtagtcgaac agggtgtgcc
    39961 tttgtctcga gaaatagaca aagatgaagc ccattgtatc cacttcgtcc tgtactcaga
    40021 taaaaaagaa ccgcaaggaa ctgtacgtct tttgccttta gaaaacggaa aaatgaaatt
    40081 acagcggatg gcgattcttt ctgaatacag acaccaaggg ttaggaaaaa tattgattga
    40141 agaagcagaa aactttgcta agaatcaagg ctataatacg attttattag gggcacagtc
    40201 cacagctgaa actttttacg aaaaactagg atatacagct tacggcgatc cttttgaaga
    40261 tgctggcatg cctcatattt atatgaaaaa gactttataa aaatttattt cgaaaaaagc
    40321 aaaaaacagc aagcttttga gaaaaatctc tcactggctt actgttcttt tttgtgttta
    40381 cttacgcgac aattgcttgt aacggttata ccaaatatca atatagcctt ccgagaacgg
    40441 gccatctcca ttattgatcc agtcaaccag aatcttcaca ttttctttta ggatgaagtc
    40501 aatatcgttc gggtaattca tcattttgct gtgcatctca tattcatcga catccaatag
    40561 tcgtttctcg ccgtcaggaa ataccttgat atccaagtca tagtcgatat atttcaaggc
    40621 ctcatcgtcc agcaaaaaag gtgaagctag attacaataa taggaaaccc ccttttctct
    40681 gatcattgct attacattga accagtattt tttatgaaaa taaacaatcg ctggttcgcg
    40741 cgttacccat cggcgtccat cagattcagt gactaatgtg tgatcattca cgccgatcat
    40801 agagtgttcg cttgttttta ataccatggt atctcgccac gttcgatgca atttgccgtc
    40861 gtgcttgtaa ctttggatcg tcacaaactc tccttctttt ggaactccca tagcaaccct
    40921 tccttaagca gcattttgtg ctttgtgttt gggtgttcat tacaccgaca tcataattat
    40981 tatatcaata aaaatgagct ttgcctagaa aggattccta ttgtttcgat ttttctctaa
    41041 ctgatctacc agtttcattt ggaccttagg aaaaacgacc gaatcaaatg catcaggctt
    41101 caaccacttc gaagttttgt tctcggtaaa ttcttgttct gctccctcgg ttgcccgtcc
    41161 gtaaaaaagg agaacatgcc atttcagatg actaaaaata tgagtaactt ctcctaaatg
    41221 tcgtgtctgc caaacaaaga gttcctgctt ttcaaatggg agattttgct cttcttctgc
    41281 tactaggtca tcaaacagat cgatttctgg ctttgtttcc cattcttttt tcaatcgctc
    41341 atactcctct tgtgtcactt ccatcattgg aaatgtccac atattcgcca gcaatttttg
    41401 gctatctctt tcttcaaaat aatacgctcc agaatgattt tgaagagctg cactgatata
    41461 ataaacgtct tttggctttg ctttttttgt ttttacagga aaactcgttt ggattcctcg
    41521 tttgttagct aaacaaaagg cttggatcgg acaagtctca cactttggag aagttggtgt
    41581 acagatagct gaacctagat ccatcattgc ttggttgaat tcacctggat gcttttcatc
    41641 aatgattttc cgcatcgctt catcaaagat tttcctgcta gaagcttttg cgatgtctgc
    41701 ttcaatgcaa aacaatctgc tgactactcg catcacgttg ccgtcaactg caggttctgg
    41761 aagtccaaat gcgatacttg caatcgcgcc tgtcgtatat ggtcctattc ccttcaatga
    41821 gctaatttct tcaggcgttt gcggcatttc cccatcaaat tctgacatga tctgtttagc
    41881 agcagcttgg atgttccggg ctcttgagta ataaccaagg ccctcccatg cttttaaaag
    41941 cttttcttct ggagcatttg ctagctcttc aattgtagga aaccattcca tgaaacgata
    42001 aaaataatcg atcactgtgt ctactctggt ttgctgaagc atgatctcag agatccagat
    42061 acgataagga tcacgattat agcgccaagg caggtttctt ttttcttgtt cataccattg
    42121 aatgaactga tcttgaaatt cttttgtttc tttatctgtc catttttccc attctttatt
    42181 cactttcctc ttccttttcc gtaatgaatc gctggatcat atccaaatca aatccttttt
    42241 gatataagct ttgctttact tttagatttc tttttttagg ttcaaacctt aaatttcttc
    42301 gccatagttt atctccttgt ttgactaaat aatcatattc tatttcttga tctgcttctt
    42361 gcggaagatc agctatcgct tgttggatca cttcttgaga aaagcctttc gtcatcaatg
    42421 tttgttggat ttttctcaat aattcttttt ggctttttcc gtgatttttt ccaaacgctt
    42481 tttcggctgt ctgatgtgca ttttgaactt ggtcttcaaa tgtatattgg ctgagcgctt
    42541 gttcaatgat ttcaggtttc aaaccttttt gctgcatctg ctgcgctaat ttctttggtc
    42601 ctttgtcact taagcgcata ttcgtgcgca cataactttc cccatagacc aaatcatcga
    42661 caaggtccaa ttcttttaag cgggctacga ttttatttcg atcttcttga aggatttcct
    42721 tttcttttaa gtatgttcgg atttcttttt ccgatcgcaa ctgataactt aagtaattca
    42781 ttgctaggtg aaaaccgaaa tcagctccgc tactcttctt gatctcttgg atagtttctt
    42841 cgtctaattc ccgtcctttt aataatcgat agcgtactaa tacatcttca gatacttgta
    42901 aagcttctcc ttcagataaa tctacgcgat agaaagggcc tttgccttta ctgattctcg
    42961 taacggttaa cataaacatc ctcctcgaac atatattctc tatcatacca cagaaaatcc
    43021 ccgtaatcag gtattatatg ttagaataaa ccacagaaaa aagaaaaagg gagatactta
    43081 tggcagaaac aattgtcaaa actggacaaa cggttccttt gaaaatcaag cgtttaggca
    43141 taaatggtga aggaatcggt tatttcaaac ggttgatcat atttgttcca tatgcactac
    43201 caaaagaaga agtactagtg aaaatcacga aagcaactcc tcgctatgca gaaggagaat
    43261 taataaaagt caaaaaaaca agcaaagatc gcgtagtggc accatgtcct gtttactatg
    43321 aatgcggtgg ctgtcaatta caacacttag cttatcaagc tcaattggat tttaaaaagg
    43381 atctgctttt gcaagcattg gaaaaattca aaccagcagg ctttcgatct tatcaacttt
    43441 tgccgacgat cgggatggat gagccttggc attatagaaa caaagcacaa tttcagttac
    43501 gaaaaaataa gcagactcaa aaaattgaag ctggtttata cgaagcaaac tctcatcagt
    43561 tagtccctat aacagactgc ttggttcaag aacctcgaac acaaaaagta atgaatactg
    43621 ttgttcaact attgaataaa tttgatgcac ccatctatga tgaacggaca aacagtggaa
    43681 tcttccgcac aatcatggtt agaatcggtg ttaaaactgg ggagttacaa gttgttttta
    43741 ttactcgcag taaaaaattc ccgcaaaaaa acgcaatgat ccgtgagatc aatgaacgac
    43801 tgcccgaagt tgtttcaatc atgcaaaatg tccaggcaca aaaaacgtct ctcgtgatgg
    43861 gggatgaaac gatccactta tggggaaaag aagccattga agaacaaatc aatgaagtga
    43921 ctttcgatct ttctcctcgt gccttctttc aactcaatcc tcagcagacc gaattgcttt
    43981 atggcgaagg aatcaaagca ttagatgtcc agcctaatga aacgatcgtg gatgcttatt
    44041 gcggagttgg gacgatcggc ttaagtgtag caaaacaagc caaagaagta cggggaatgg
    44101 ataccgttcc tcaagcaatc gctgatgcaa aaaaaaatgc ggaaagatta ggatatcaca
    44161 acactcgata tgaagtcggg acagcagagc aagttctgcc taaatggttg aatgaaggtt
    44221 ttcagcctga tggtatcatc gtagatccac cacgtacggg tttggataac gcattgatcc
    44281 aatcattatt gaaataccct ccaaaaaaac ttgtttatat ctcctgtaat gtttctacac
    44341 ttgccagaga tctggttaat ttaagtaaaa agttcaagat tgaatattta cagtccgtcg
    44401 acatgtttcc tcagactgca cgttgtgaag ttgtcgtgaa gatgacgaga ctcgctgact
    44461 aaatgaaaga ggttgtgaaa aagtctgccc tgtatcaagt aataagaaca gccaaacaaa
    44521 aatagctctt catgttttat gaatactgta cttgtgaccg aagagttaac aggaggacac
    44581 tatttattta aaaaaagggt tgtgacatag tttttgtcac agcccttttt gattattatt
    44641 ggatattcac gtctatcact tgataaaatg catttgtcgt atcgctgata ttccatactg
    44701 ctaaaatcac attatatcct tttcgatcct gcggaagtgt gatcgtttgg ttgactgttt
    44761 ttggtggaac agttgctttg tcgtctattt ttgtgatcaa ttcaaaatca ctaaatttca
    44821 aaggttgatt aggattccaa gttggtttgg taatgtagta atcccaagta cttgtccgat
    44881 gttgtgctgt taaattccaa gtaatattta atgttcctgg attaaccatg tttttatgcc
    44941 atctgttaga tgtctgttca tctaaaggct caaagccgct gactcctgca ctagcaattt
    45001 ttccatcaat gaatgtattt ttggtagctt cgatactttg cggttcccat tgtgctcttc
    45061 cgacattttg atttaagttt cctgctgctg atgttcctag gtatgcacgg cttcctggag
    45121 aagtaatata accatgcgca aaacctggaa tgctaaaacc gaacaaccct aaactaacta
    45181 acccaataaa caataacgta ctaatctttt tcatgtagaa acctccttca tttgataacc
    45241 acattgtaaa cgctttattg tattaacaca aacattatgc ttttataatt ttatgttgaa
    45301 gtaaaaaagg tgaaaaaagt aagatgcaga ttataacaga agtagacgag aaaagtacaa
    45361 atagaaaaca tgagaatcaa atcatatgat ctttttcaaa aacatcattc atataaacaa
    45421 atgttcaact ttttaataac aacaattatc aatttttttc ttacttcaca aactaaatac
    45481 aggtcttgct gtgagccttc atggtaaact aatattatag aaaggagtta gtaaaatgaa
    45541 gatgataaaa gatattcgtt tttgggtttg tgttatagga attgtcatat taggcttttt
    45601 atcagggttg cttagcggaa atcccggaaa atattactat tctttgcaac ttccaccatt
    45661 tgcaccacct agctggatat ttgggccgat gtggacctta ctgtatatat tgatgggtat
    45721 ttctctttat ttgttactta atcacaacaa caaaaaacag cgaaacaatc ttgtcggtct
    45781 ttttgtgatt cagttcattt ttaattttat atggtctgct ctatttttta atttaagaaa
    45841 tattttcatt gcagcaatcg atattacact tttagttatt ttcttgtcag tgcttatgta
    45901 tcagttgtgg ctgcatcatc gcctggcaat gtggctcatg attccttatt atttatgggt
    45961 actattcgca actctattga attattcaat ttatttttta aactaagcgc taaaaagaga
    46021 cgtcctgtaa tttaacacat agaaaaagtg ccacctaagt tagatttttt gtctaattta
    46081 ggtggcactc tttattaacc aaactatttt tttctagtac ccacttgttg ttccatactc
    46141 attattctgg tcataaccat aaccattttg ttcctgtcca gcgtaaggat cataactttg
    46201 agtatcttga cttggtgtat agtactgact tgtatcttct gtttgctgat aataggtatt
    46261 cggatcttgg tactgatcat atgtgttttc tgaataggaa gaataatcgg tgtacccttc
    46321 actattcgat ccatcaccgt ttgtcgaatc gccatcttcc gaatcatcaa agaacatcat
    46381 tgaagcattc tcatttttca aattaggtaa tgtatcgctt gtttttatat ttaattgttt
    46441 cttcagttca ttttggatcg aaagaagatc attttttcct aaaatttgat agtagatatc
    46501 attgatcatt tgtccttcgc cttgcaactg gtcttgtttg attgtttcaa acgccggggt
    46561 gtagttcgtc gctacatcaa gcatgtcatc ccaatctaag tccgtcgtca cattgttctc
    46621 aactgctttt aaaatttttc tataattgct tacgccatct aaacttaaaa ctttattgac
    46681 gattttcgtc actacttccc gctgacgacg ttgtcgaccg atatcgcctt ctggatcttc
    46741 gtgtcgcatt cgagaatagg ctaaaccttt ttctccattc aatgtttgtt cacctactgg
    46801 tacatggaca ccatccaaag taaagtcaat tttattattc actttgatgc caccgaccgc
    46861 attgatcaaa tcttccatgc catccaaatt gatcgttaca taatgatcaa taggaatatc
    46921 gagcagttgc tcaattgaat ccatggccat ttcgacacca ccaaatgcgt aggcatgatt
    46981 taatttatct accgttccat aacctacgat attcgtataa atatctcggt ccaaactgat
    47041 gatcgttgat tttttttgtt tcggattaac tgttactacc atcatcgtat cagaacgtcc
    47101 ttgttccgtt cttcctaatc caccggtatc taaacctaat agcaaaaccg aaaaaggttc
    47161 tttgtcatca atgcttactc tctcagaacg tttggaggat attcgattag agtttttaga
    47221 aattttgttt actgtttggc tcgcttctcc cataaatctg attccgtatg ctgataatcc
    47281 ggcaatcagc aaaacgaata cccctaacaa ggttaataga actttttgcc atcgcttcat
    47341 aatacacctc tgtttcacat tttctaaaat attgtctcat ataactgttc aatcagcaaa
    47401 ttcacttttt aatcataaga aaactttaaa aaacattttt gtgtaacgat tattattttt
    47461 taaaatttct caaaattctt aactatcata ccataccgtg aaaaagatcg aaagaccgaa
    47521 tacacgcagt tcgcaatcgt tttatctttt tttatgtatt ttttccagaa aaagcgaaca
    47581 acaaggtatt ttccaaataa tcgtgcagta aaatgatcgc acataccttt cccatctttt
    47641 taacagtctt tgcctaccgt tcagattatc attcgatttc acgacaattt cttcctatga
    47701 ctggtccttt tgttaaaccc atcttctatt cgttttattt ccagctcact gcatggctct
    47761 taaaatgact cgaactagtg attgcattac catcatcttt taatggatag atatgctcct
    47821 cttcaaagta aaacgatttt cttttaaagt aatagaattg acatggtaat gagtatgtat
    47881 actagtggtt tcacaaatgg tcttttattc aacatccaaa aactgaaatt tctttaaaat
    47941 ccattactaa cgaagaaaat gttccttgct tgataattag ttaggacatg tcaagtgaac
    48001 aaatgcattt acttagccaa aaaatctaaa aacttcataa atagacaaaa agacacgact
    48061 ctctaagaag tcgtgtcttt attcaacaaa ttattataat ttagtcactt cagcagcttg
    48121 aggtccgcgt gcaccttcaa caatcgtgaa ttctacttct tgaccttctt ctaggctctt
    48181 gaagccgtct ccttgaattg ctgagaaatg aacaaatacg tcatctccgc cgtctactgt
    48241 aataaaccca aatccttttt cattgttgaa ccatttaacc gttccgtgtt ccataaatgt
    48301 atatcctcca aaaaagttct tgcaagtaac cttgcaagaa cattataccc aatttagaaa
    48361 acgctagcaa gctttcgctc ttttattttc caaattattt ttaagactga tatgacggag
    48421 gaaatggtta ttttgctgct tcgaaacgtt tgtttacttc atcccaatta ataacattcc
    48481 agaatgctgc aatataatct ggtcggacat ttttatattt caaataataa gcatgttccc
    48541 aaacgtccaa acctagaatt ggtgtctttc cttccatcaa tggagaatct tgatttgcag
    48601 tagaggtaat agctaatttt ccattttcca ttacaagcca agcccatcca gaaccaaatc
    48661 gtccagcggc tgcttttttg aattcttctt taaaagaaga aaaatcacca aaagcttcat
    48721 taatcgcttc ttttatttct cctgtaggtt cgccaccagc atttggtgcc atgatttccc
    48781 agaaaaatga atggttagca tgtccgccac cattgttacg tacagctgtc ttgatatctg
    48841 ttggaatagc gtccatatca gataataatt cttctattgt tttttcgcct aattctgggt
    48901 atttctcaat tgctgaattt aaattcgtca cataagtatt gtgatgctta tcatgatgca
    48961 gatgcatcgt ttcttcgtca atataaggtt ccaatgcgtc atatgcataa ggtagatctg
    49021 gtaatgtgta agtcataaaa aaattcctcc tcaatgtttt cttaataatg tctacattac
    49081 aaagagtaac aaagagaagg aaattcttca attgttatgc ctagtcgtct ttttcacttt
    49141 gacctacttc ttcttcaaaa acctcagttt ctttaaaaat aaacaacttg ctgaaaatat
    49201 agttcgcaag gataacaata atttgagtga tgattttcgc cacatactca ttgctgttca
    49261 taacattgat caacaatacc attgccccca tgtccaatcc gtaagaaagg atacggtaga
    49321 agaagaactt accgcattca ataagtgcat gtgtaaaatt cggtgatttt gaatggaata
    49381 cccaaagttt gttcgttaca aaagcaaaca atacagaaca aaaccacgaa atagaattgg
    49441 ataaggccat acttaaatca aaatattggc gtgcgagagc aaaactaaca aaatttacaa
    49501 tcgtagccaa accaccaaaa aagagataga ctagtatctc ccaatatcct tttgcttcta
    49561 aatatccttt taactgtcga tactgcttca tgagccaacc taccttatta aaaattctta
    49621 tttatcatac tctatatttc aataactttc atctttattt aaaaaaatta attttttttg
    49681 atcctttgcc tttgtctctg cttggatcgt cacatgtgta ataccatatt ttaattttaa
    49741 taaagaaatt atacgaggat atatcttttc aatctcgctt agtagctgat cttcaaaatc
    49801 aatatgtccg tcgaaaataa ttatcttttc gctatactgc caaatatgga catgatgaac
    49861 atcctttacc ccatcgattg cttcaatttc ttgttccatt ttttcatagt cgatagcagg
    49921 tgcactttgt atcaaaatag cggcagcttt tttgatcacc attatcgctt ctatcaatat
    49981 atatatcgaa atgatcagtg taataactgg atcgatccag tagatatcga aaaaacggat
    50041 caaaattgct ccgataatca cacttaccga agacagtgta tcacttaaca aatgcaaata
    50101 actagatttt atattcaaac tttcatctgc ttcttgtcgt aataataata ctgagaacaa
    50161 attcgcgagc aatccaataa ctgctactgt tagcatcaaa tgactattta tcttttctgg
    50221 tgaagtgaac cgcttgaatg cttcaacggt taaaaacaag gataatatga tcaatatgaa
    50281 tgagttgatg aaagcactca atatttctaa acgctggtag ccatacgtac gttttttatt
    50341 tgcttctttt cgggccattt tttgtgcccc gtaagaaaaa ataattgcca atgtatcact
    50401 aaggttatgg aaagcatctg aaacaagaga caaactccct gacataatcc ctccaataaa
    50461 ttctgataaa gtgatcaccg cattcaaaac cactactcca aatagttttt ttgatgatct
    50521 ctgtggctgt gtaggcacta ttccttcctc cattttattt atattggata gtctttagac
    50581 aagaataaca tttttttgat atttcaccaa tcattcagct gtttccttaa agcacttgta
    50641 tttcacttga tacttcgcta gaattgcaag tgatgacact actagatgag gagtacttat
    50701 gacaacaaaa caattaatta tcagttcctt tatacgattc aaagacctaa aggaggcgag
    50761 aaatgtccca ttttggaaag ccattgtcta tcttttagtt ttgagtataa ttatggcttt
    50821 gccaatctct tttcaagttt ttcaagtctt aaacaacatt caattggatg ggcaaaagat
    50881 tgctactcgc attcctgatt ttacaatcca aaacgggcag cttcaaaccg aagaaaaaga
    50941 aggattcatt taccaaacaa actccattat cttcacattt gatccagagg gaaaacgaac
    51001 agaacaggac atctctactg atttgatggg gaattttgtt agtgtcggga tgttaaaaaa
    51061 caaacttatc atagctcttc ctaatacagg cacgacttct gctttgttga acaataacca
    51121 attagaactt ccctacacca atgaatcttt aaaaaactta acaggtaagc agctccgttc
    51181 ttttttaagt gaagcatcta taccactttg gataaaagtc ctgacattta tattttctat
    51241 ttatcctagt tttctgaatc tgctgatcac tttgctattt accaacattg ctgcttttct
    51301 ctatgcacgc tttcgactaa caaaagctac ttttcttgat tgtttaaaaa cattgatcta
    51361 ttcaatttca ttgcctacta taattgcaac aatcttgatg gtctttcttc cttcttttga
    51421 cactagcgcc ttcattgctt ttgcaggaat ctttattttt gctcaagctg tcaaaggatg
    51481 ggcaaaaata tcgatcaatt aagaaataaa gacaactcgt tatttctact tcaatagacc
    51541 cttttagagg ttgtgacatt tttttgtcac agcccctttt ttatttgaaa aatatttctt
    51601 tctcaaaaaa caagcaaggc gcttcaaagt tcttcttgta tgcgctacac ttagagtaaa
    51661 gaaaggcggg aaattaacta tgtcagaaag aatcatttat gcagatcgtc catttcgtga
    51721 tgaatttatc gaagaaatcc atactatagc gcctggttat atctttaaaa cagaattaca
    51781 accagaggat ctacaaaatg tagagatcag tttgggctgg aactcagact accaagaaaa
    51841 actattagcc tcttctacct tgaaatgggt ccaatctatc tcagctggtg ttgatcagct
    51901 accccttgag actttttcaa agaaacatat tttactttca aatggtagtg gcatccacag
    51961 tgaatcgatt acggagcatg tcttaggaat catccttggg tattctcgtg gtctttttca
    52021 agcacaaaag gcacagagtg acatgaaatg gttaggttca tcggtccatt accaatctat
    52081 ccaagggaaa aaaatactaa tcattggaac tggccatatt ggaaaaatga ttgcaaaaaa
    52141 atgcaaagca ttagacatga actgctatgg aatcaataca tccggtcatc cagcagaagg
    52201 aatggaaaag actttttctt taaatcaact aaaggaagtt cttcctgaag tagatttcgt
    52261 agtcaatatc ttacctctaa cggaggaaac aactgggctc tttgatcagc atatgtttga
    52321 acactttgat ccaaaatctg tattcatcaa tgttggccgt ggtgcttctg ttaagacaca
    52381 agatctggtg caggctttaa ataaccagca actttccttt gcagcattag acgtttttga
    52441 ggaagagcct cttccacaag atcatcctct ttggaaaatg gacaatgtac tgattacttc
    52501 ccacattgca ggtttgacac ctgattttca aaagaaatta atggctattt ttttaaccaa
    52561 tctgaaaagc tactttgcca cccatgagct tcaaaccaat caagtaaaat tgtctgcagg
    52621 atattaatag ctgaaaacaa tattttcaaa agaaaaaaga gaaggtgaca aaaattgtgt
    52681 caccctctct ttttttattg ttttttaaag tgataggttg gctcctccag gttgggatca
    52741 taatcaacaa gtaaatcata tcctttaaag aaccattcat ctgcttcctc gataaaaaaa
    52801 agtgtcccat caatttccac tttctttaca ggatgttctg gctgttcaac tgacattcca
    52861 atcgaaaaac catcatgaac ctctgttttg ccgtagactt ttccaaaaaa acgtattccg
    52921 taagtttctg gcagatcaat ttctgagtca aaccactttt gtgcttttgg cgttaccgtt
    52981 aatttcatcc caacaaccta ctttctcttt tctttctatt gattcatctt atcgtctaga
    53041 atatccacat cgcctgtctc tccaataacc agtagattat cattttcacg aacatattca
    53101 tctgctgcag gagaagcgat aaccgtttga tctactcttc gtatggcgac tactgttaag
    53161 tcaaaacgtt gcctgaaatt taattcagct aatgttttgt tgaaaaattt aggattggag
    53221 actcggattt ctgctaaaga atatttatct gacaactcta ggtaatctaa aatattcttt
    53281 gacactaaat tatgcgcaat ccttattccc atgtctcgct cgggatggac gacgcgatca
    53341 gctccgatct tttcaagtac tctggcatga tactcatttt gggcttttgc taaaatattt
    53401 ggtacgccca tttcctttac catcagagta actaagatac tggcttgaat atcttctcca
    53461 atagcgacaa ttacatgatc gaaatttctt atgcctaatg atcgaagtgt catttcatcc
    53521 tgtgcatttg ccacaacagc atgagtggct atattcatat attcattgac ccgatcttca
    53581 ttactatcaa tagccagtac ttcttgacca gcttcgatca gtgttcggca gatacttccg
    53641 ccaaatcgtc caagacctac aattgcaaaa ttttgtttca ccgttttcct cctttagtat
    53701 cttcttttct cagtataaca aagcctttac aaaaacaaaa gcaagcatca ttattgtaaa
    53761 aaagccaaga aaaataatag ttattttctc agcttttgat tatcctcttt atcatcgttt
    53821 ttatttcacc aaaccatgtt tgaatgcata gatagcggct tgtgtacggt cttccacttc
    53881 tagcttagcc aatatattgg aaacatgtgt ttttactgtt ttcagtgtaa taaacaattc
    53941 gtccgctatt tcctgattac tttttccttc agaaatcagc attaaaattt cattttcccg
    54001 attcgttagt tcttcatgta atacaggctc atttcgccga ctcatttttt ccatcatttt
    54061 tgttgtcact tctggttcta atactcgctc gccacgttgc gttgccctta tagcatcagc
    54121 aatttcatgt gcggtagagg tcttcaacaa ataccctgct gcacctgctt caatggcagg
    54181 ataaactttt tcgtcatcaa taaaactggt tacgataatg attttagctt ctggccaatc
    54241 ttttaagatt gcttttgttg attcgatacc atccatttct tccatgacta agtccattaa
    54301 aatgacgtcc ggtcgaagtg tcatcgcctt ctcatagcct tgtcgtccat tttcagcttc
    54361 tccaattact tcaatgtctt cttgaataga taaataaaaa gagacgccta agcgcaccat
    54421 ttcatggtca tctactaata aaacttttat catccttatc tatgcctcct tcatcaaagg
    54481 gaccttgatt tctacacttg taccttgacc tttaaaacta atgattttta ctgttccacc
    54541 aataccagct actcgttctt tgatattgtt caatccataa cttcccgttt tcgtttcatt
    54601 catattaaac cctgttccgt cgtcaataat acgtaacaaa agattattgt ctattttgtg
    54661 caaatatacc tctaattcat tggctttagc atgtcttaat gtatttgata acaattcttg
    54721 aacgattcgg aacaagtgat cctcaatgga actagatagt tttacatctt ctacatccca
    54781 tttcagcgaa atctggattt tattttgcaa ttccttcaat aactgctcga taccttgctt
    54841 taaacttttc tcttctaaat tgactggacg tagatgaaga agcagcgcac gcatctcaga
    54901 ctgggaagcg ttgatgatct ctgctaccat tttcaactgc ttgcgaaaca tttctggtgt
    54961 ctcgcttttt tctgcttgct ccgtcaatgc cgacatcatc atcattgctg caaacaattg
    55021 ttgcgaaact gaatcatgca gctcacgggc taatcgatgt ctttctaatt ctaaaatttc
    55081 ttctttggtt tgtccatcta catattgggg acggctcgtt acaatttgta attcactaga
    55141 tacttcaatc attttttctt ttatcttagt gatttcctta tcaatatctt tgatgtataa
    55201 atcgtccgat gcacttggga tcggaagaag caacaatttg gattcataat tgccagaaga
    55261 aagtgcacgc agcttttctt cgattttccc gtattttgtc ttttgaataa gtgataataa
    55321 tagaaagaca attaatccta cacctaagga aatggctaac aaatggaaga taagcggaac
    55381 atataataaa cgtgcacgca gtaattctcc ccaccaatga ctttgattgc tggcataaaa
    55441 ataagtgaaa agtgaaaata gaataataag gaaagccgca atccccgaat aaacagctag
    55501 catcgctctg gatatttttc ccatcatatt cgtatcacct cgacatctcc aatcaaggta
    55561 ttagtaataa tcttcaatct acgagggttt tcatcataat cactgctgta gattttgatt
    55621 tgttcatttt tcaaagaaaa ttgctcttct tcaaacaaga catttcctac taatgtcgca
    55681 tgctctaatc ggatggctac gcccaaaggt actaagatcc gtgttctgcc tatccctttt
    55741 cttacaatca caatattatc atcttttggc aaaagcgtat tgcccaaatc tatgatagta
    55801 tcaccagaaa tgacggcgat gttgatatcg tcccattcat agacgtcgtt tccaatacgt
    55861 tggttaccga ataattgctg tcttttccgc tcattattat gtgtttttaa ttgctctgtt
    55921 tggatcatca tgatctgttt ctttcgccaa aaagcatttt tggttaaatc tatccctgaa
    55981 atctctacac ctttcagacc aataaataaa acggcaaata cagccatcat ccataaagca
    56041 ggactgttga ctaagctaaa aaaaatgacc aaacttccta atatcaattg aaaattttga
    56101 aatttagtac gaggatgttt gcgcatagct agatatatat tgaaaatacc gaatatcact
    56161 aaaagcaaaa gtccagtatt gtttacgatt tgccaaacag caaataacag cagtagtgct
    56221 tcaactacca caaaaaaacg ccaagaacta ttcatcgctc tttctccctc ctgacacatt
    56281 ctcatttcat catacctatt tttttaactg ttggctatag gactttagat gtaagatcgt
    56341 ttgttgaaat ctaaaataca caaagagaaa aagatctaga gtgtatcatc agtaagatga
    56401 actctctaga tctttcagtc agactacgct tgttctactt tgacgatttt aactaacata
    56461 tcgccacctg gagtagcaat agttacttca tcatttttac gtttgccaat caatgcttgc
    56521 gcaataggag aatcattgga aattttgcca gaaaacggat ctgcttcagc gcttccgaca
    56581 atcgtgtact cttcttcttc tccatctggt agttcgatga atgtaactgt tttaccaatt
    56641 gatacctcat ctgcatctac accgtcgtta tcgatgattt gagcaaaacg aatcatattt
    56701 tcaattgttg tgattcttcc ttcaacaaat gcttgttcat ctttcgctga ttcatattca
    56761 gagttttcgg aaagatctcc gaaaccgcgg gcaattttga ttcgttcaat gatttctccg
    56821 cgtttgactg tttttagttc ttctaattct ttttctaatt tttctttacc ttctagagtc
    56881 attggataaa ctttctctac catgtgtaac gtctcctttt ttcgataaaa taccgcaaaa
    56941 ggtaatcttt tgaggaatat agtccaaaaa agattaccac gcttttcttc aaatgtaaat
    57001 gtttttctaa aaatgatcaa tgtctagagc ctgtttttct aagaattatt tacatatttt
    57061 tccactaatt ccatatgttc ttcataagtt ttagcgaaat aaacatttcc agtgctcgta
    57121 tctgctacga aataataata gtcattttct gctggttcta atactgcctt gattgcctct
    57181 tcgcttggat tgtcaaaagg tccaggtcca tagccggtat tggtatacaa attatatggt
    57241 gaatctacag ctgtatcttc atacgtcact aattctttgt gttcacctaa tgcgtataaa
    57301 acagagatat ctgactgaag tggcatattt gctttgattc ggttaaagaa gacttgtgca
    57361 atgtttttac gatcattttc ttttacgcct tctttttcaa ctagagaagc tagagttaaa
    57421 acttcttgta cagtcaaatt tttctgcttg atagctgaat aatagttttg catgaccgta
    57481 ttcgtcttgt tcaccatttc aatcactaga tccttaagcg aagtactcgt gtaataatca
    57541 tatgtggctg ggaataagta accttccaaa cggtattttg tgttctcagc tttagatgca
    57601 ctttccaaca gttctgggaa tttttggtgc aactcgttaa agaaagtctc atcattcact
    57661 aaatctaaaa attctttctt gtctttacca gttaccttcg ctacccgttc agcaatctga
    57721 tcgatatcgt acccttctgg aatggcaatt ttcccatctg caacttttgt tggctcagaa
    57781 gtaccgcctt cttgcaactg tttgccaatc tcgtcaagag tcatattagg cgctaactga
    57841 taatagccag cttgaaagcc agttaaattt ttaaattttg tataataatt gaaaacaatc
    57901 ccgcttttaa taatattgtc cttctccaaa atctcaccaa tctgcttgtt agaagagcca
    57961 ctcgggatct cgacttggac taattggtca tctgatttat ctaaaggctt caacccgcta
    58021 tctacataac gatacacggt aaatccaaga aatccgccaa taatcaataa tgtaagagca
    58081 atcactaaaa tgatcttcct cacaatctta tcttcttttt tacgcagatt tctccgcttg
    58141 tcgattatat ctgctgtagc tgccttactg gcttcttttt tatctttact tgggtgttgt
    58201 ttgtttcctg acaaaacaac tcctccttac tatcaagttc gtaactttat tcattataca
    58261 tgatatttga attggcgtga atgattttat ttaaatattc tatcaaaaat gtaagtagta
    58321 aatccattac tataagatta aaataaatgt tatcaagata caagctattt tagctttatt
    58381 ctttctgtaa aaaagaaagg agactaaata aactattatg aaaaaaggaa aacatgctaa
    58441 aaaaagaaaa tattcatttt taatgatcgt tgtcgtgttg tttagcctta gtgcgttctc
    58501 tacaggaact attcttggat ggcaatttta caataatgaa cactctcaga tagttgccca
    58561 tgctcaatca gctcaaaaaa agttgatact gactaccaat gaacaacagc tcgttgaaaa
    58621 aatcgatcaa ctattaagaa aaaatgatta tattggctca atttacgtaa agaaaaataa
    58681 tcgcatcatc atggaaaaag gctatggcta tgcgaataaa ctcacgcaac aaccaaatga
    58741 tccttctctt tattatcaga ttggttcggt tcaaaaagca ttgactactc ttttgatttt
    58801 aaaacaagtc gagcgtgggc acctttcttt agatactaag ctggctcaat tctatccaca
    58861 aattgctggc agccagcaaa ttactatccg tgacttgctg tatatgcgct caggcttgca
    58921 ccgaactgct tctccaacca taccgatgac tgatgaagaa gtcgttcaat ttgcgattca
    58981 gcacttaaaa tttacagatt atcagacctc tcattatgat tcattgaact ttaccatatt
    59041 gactggaatt ttgatcaaat taacaaatca accgtatgaa aaattattga ccgatgatat
    59101 catcgaacct ttaggattac agcatacaaa attttatgac caagtcaaaa attcatccaa
    59161 tcatgcacta tcctatcaaa tgtctaaaga ggatgattac tttaaaccac tgacagaatc
    59221 tgaaacagag atccataacg aattagggac tggtaatatc agtatgtccg tctatgattt
    59281 aaatacgctg tttacacaag ttttatctgg aaaactagtt tccaaagact tactcttctc
    59341 attatggcgt gaaaatgcga atggacatcc atatagtggt ggggtatata gcggagataa
    59401 ttatatcctg tcgcaaggaa atatcgactc ttttgataca tctgctatat ttagcaaaga
    59461 ttcacaggat gctatcatca tggaaagcaa tataaaagct gacaaaacta tcaaactgcc
    59521 tactgctgat ctaagaaacc aaatctatga cctgatggaa ggaactacta agttggcaaa
    59581 tagctgatat gatgaaaaga tagcaaatac tacttctttg aatagcattt gcttaaaaaa
    59641 agtactcgac taaacgtagg aaagagtgtg ggacaaatct aaaaatcaat ttttgctaca
    59701 gactttaatt ccaaataaac agaacagaaa gaggtgttct tctttctgtt ctgtccaaat
    59761 tattctaaga tttctcttta ccaacattat ttgacaaagg gcctattaaa tctaaaatag
    59821 tatctttaga ttgctaaaat atgtgctagc aaatcattca tggcttgttc ttatttttaa
    59881 ttttatgcaa taaaaaagaa gaacaattag cgtgattata gaaataaata atgagatttt
    59941 agaaaaaaat gtgtatgaat acctgattgt tactttattt attccacttt cactttttac
    60001 tgtaacaaaa ggacctcctt gttttagtac tgtagcattt tttgaattaa cagtaaccgt
    60061 taatccttta taccggaata caggtaaaac tattgttttg ccttttgaag atttaaacgt
    60121 aaatgtaatt tcatctttat ttggagaaaa gctactataa ataacttgac catcttctgt
    60181 aacttgatgg tttttcaaaa gcaattgatc ttttttatag cctataggta cataatcaaa
    60241 attctcaaat tcttcaagtt tattttccat ttgttcatta gaataagttc cttgaaaatt
    60301 catttctttc accatgttaa ctactgatga ataatttaaa attgaaatag ctaatattaa
    60361 taatagtata aaatttcttc tccttgtata agaaaatttt tccaactgtg gagaaataaa
    60421 tagagatact gaaaaagata tgaacaatgt tgaaaatatc ataaaacgcc aaggagcttg
    60481 aataatattt aaaggagtat tttgtaaggc aaaccatgga aatatttttg tacaaagtag
    60541 aatagatatt atacccatta tataagtgat tttagataag attcctaatt ttttaaagtt
    60601 aaatgttagt ataattaaac aaataagcaa agttaagcca ataccaaatg atagtaattc
    60661 tgaatctata cttccaatca aaaactcttt acccagataa attgctcttt tttgtaatat
    60721 atccacataa ggtctattca gatcttgata caatgtctgc tcaatcatag gacctataaa
    60781 cgctagtgaa agaagtaaag taactatagc agcttttatt aatttaataa ttaagaagat
    60841 ttctattttc tttttccgat aaaattgaat aattaaagca attataatca ttaccatagt
    60901 catagctaca gaaagaacat gagtgtaaat taataaagtc atgctaatcg ccaacataac
    60961 ccaagattct ttttttgagt cgtaaagctt tataaacccg agtaaaataa gaggaagtat
    61021 tgacattgcg agtaattccc ccattgcccc tcgaagaaat atttctacac tcctaaaaga
    61081 agatgttgta tatataatag cgaaaaagga gctagtaaca tgttttttgg taatttcata
    61141 cattacataa tgacatataa atagagtaat gagcgtaaca atataaagaa aaaggttata
    61201 gcctattgct aaattagtaa acttgatcaa taaaaataaa ggatatagag ttaaccatgg
    61261 gtaaaaatta tttacttgca tgccatatga tctaaacgtt tcaaaattaa taggggagct
    61321 aaaaatagat tctaaactta acgcacgatt aatgtgaaat gccgtatcat aaaagccaaa
    61381 tatttccatg tttttaaatg ctggaaataa atataataaa ctaacaaatg cataaactat
    61441 aaatattttt acagaaaaaa tttttttcaa attcatatac cacct
//
LOCUS       DACCVZ010000007        59668 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.007, whole genome shotgun sequence.
ACCESSION   DACCVZ010000007 DACCVZ010000000
VERSION     DACCVZ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59668
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.007"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(451..1761)
                     /locus_tag="IVW63_000430"
     CDS             complement(451..1761)
                     /locus_tag="IVW63_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAP7858733.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="IVW63_000431"
     CDS             complement(1773..3191)
                     /locus_tag="IVW63_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7858734.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="IVW63_000432"
     CDS             complement(3431..4999)
                     /locus_tag="IVW63_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HAP7858735.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="IVW63_000433"
     CDS             complement(5003..5413)
                     /locus_tag="IVW63_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAP7858736.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="IVW63_000434"
     CDS             complement(5410..6333)
                     /locus_tag="IVW63_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HAP7858737.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="IVW63_000435"
     CDS             complement(6330..7208)
                     /locus_tag="IVW63_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAP7858738.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="IVW63_000436"
     CDS             complement(7195..8532)
                     /locus_tag="IVW63_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAP7858739.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="IVW63_000437"
     CDS             complement(8535..9638)
                     /locus_tag="IVW63_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAP7858740.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="IVW63_000438"
     CDS             complement(9712..11220)
                     /locus_tag="IVW63_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP7858741.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="IVW63_000439"
     CDS             complement(11186..11878)
                     /locus_tag="IVW63_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP7858742.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="IVW63_000440"
     CDS             complement(11900..12874)
                     /locus_tag="IVW63_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7858743.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="IVW63_000441"
     CDS             13174..14046
                     /locus_tag="IVW63_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7858744.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14504..16702)
                     /locus_tag="IVW63_000442"
     CDS             complement(14504..16702)
                     /locus_tag="IVW63_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7858745.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16934..17926
                     /locus_tag="IVW63_000443"
     CDS             16934..17926
                     /locus_tag="IVW63_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7858746.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17986..19407
                     /locus_tag="IVW63_000444"
     CDS             17986..19407
                     /locus_tag="IVW63_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAP7858747.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19400..20899
                     /locus_tag="IVW63_000445"
     CDS             19400..20899
                     /locus_tag="IVW63_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAP7858748.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20938..22332
                     /gene="uxaC"
                     /locus_tag="IVW63_000446"
     CDS             20938..22332
                     /gene="uxaC"
                     /locus_tag="IVW63_000446"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAP7858749.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22491..23174
                     /locus_tag="IVW63_000447"
     CDS             22491..23174
                     /locus_tag="IVW63_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HAP7858750.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23176..24012
                     /locus_tag="IVW63_000448"
     CDS             23176..24012
                     /locus_tag="IVW63_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP7858751.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24023..25777
                     /locus_tag="IVW63_000449"
     CDS             24023..25777
                     /locus_tag="IVW63_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7858752.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26053..26394)
                     /locus_tag="IVW63_000450"
     CDS             complement(26053..26394)
                     /locus_tag="IVW63_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAP7858753.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26462..28633)
                     /locus_tag="IVW63_000451"
     CDS             complement(26462..28633)
                     /locus_tag="IVW63_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAP7858754.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28844..29701
                     /locus_tag="IVW63_000452"
     CDS             28844..29701
                     /locus_tag="IVW63_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP7858755.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(29772..30629)
                     /locus_tag="IVW63_000453"
     CDS             complement(29772..30629)
                     /locus_tag="IVW63_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP7858756.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30614..33316)
                     /locus_tag="IVW63_000454"
     CDS             complement(30614..33316)
                     /locus_tag="IVW63_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAP7858757.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33329..34618)
                     /locus_tag="IVW63_000455"
     CDS             complement(33329..34618)
                     /locus_tag="IVW63_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HAP7858758.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34768..35814
                     /locus_tag="IVW63_000456"
     CDS             34768..35814
                     /locus_tag="IVW63_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7858759.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35816..37969
                     /locus_tag="IVW63_000457"
     CDS             35816..37969
                     /locus_tag="IVW63_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAP7858760.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38442..39893)
                     /locus_tag="IVW63_000458"
     CDS             complement(38442..39893)
                     /locus_tag="IVW63_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7858761.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39890..41614)
                     /locus_tag="IVW63_000459"
     CDS             complement(39890..41614)
                     /locus_tag="IVW63_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP7858762.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41607..42221)
                     /locus_tag="IVW63_000460"
     CDS             complement(41607..42221)
                     /locus_tag="IVW63_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP7858763.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42566..44023)
                     /locus_tag="IVW63_000461"
     CDS             complement(42566..44023)
                     /locus_tag="IVW63_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7858764.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44064..44984)
                     /locus_tag="IVW63_000462"
     CDS             complement(44064..44984)
                     /locus_tag="IVW63_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7858765.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44996..45943)
                     /locus_tag="IVW63_000463"
     CDS             complement(44996..45943)
                     /locus_tag="IVW63_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7858766.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVSQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46422..47141)
                     /locus_tag="IVW63_000464"
     CDS             complement(46422..47141)
                     /locus_tag="IVW63_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAP7858767.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47190..48836)
                     /locus_tag="IVW63_000465"
     CDS             complement(47190..48836)
                     /locus_tag="IVW63_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP7858768.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49015..49605
                     /locus_tag="IVW63_000466"
     CDS             49015..49605
                     /locus_tag="IVW63_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP7858769.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49697..51202
                     /locus_tag="IVW63_000467"
     CDS             49697..51202
                     /locus_tag="IVW63_000467"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HAP7858770.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51286..52638)
                     /gene="celB"
                     /locus_tag="IVW63_000468"
     CDS             complement(51286..52638)
                     /gene="celB"
                     /locus_tag="IVW63_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAP7858771.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52638..53156)
                     /locus_tag="IVW63_000469"
     CDS             complement(52638..53156)
                     /locus_tag="IVW63_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858772.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53172..53498)
                     /locus_tag="IVW63_000470"
     CDS             complement(53172..53498)
                     /locus_tag="IVW63_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HAP7858773.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53511..55490)
                     /locus_tag="IVW63_000471"
     CDS             complement(53511..55490)
                     /locus_tag="IVW63_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP7858774.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55511..55825)
                     /locus_tag="IVW63_000472"
     CDS             complement(55511..55825)
                     /locus_tag="IVW63_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HAP7858775.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55993..56286
                     /locus_tag="IVW63_000473"
     CDS             55993..56286
                     /locus_tag="IVW63_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAP7858776.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56364..57476)
                     /locus_tag="IVW63_000474"
     CDS             complement(56364..57476)
                     /locus_tag="IVW63_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP7858777.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57863..58042
                     /locus_tag="IVW63_000475"
     CDS             57863..58042
                     /locus_tag="IVW63_000475"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858778.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58236..58406
                     /locus_tag="IVW63_000476"
     CDS             58236..58406
                     /locus_tag="IVW63_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7858779.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58830..>59668)
                     /locus_tag="IVW63_000477"
     CDS             complement(58830..>59668)
                     /locus_tag="IVW63_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP7858780.1"
                     /translation="YQLVETQAPTGYELDATPIEFEIERSQTAVVELTKANRLTPGGV
                     VLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAP
                     TGYELDATPIEFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDA
                     NGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIF
                     LTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKR
                     NI"
BASE COUNT        17833 a        12195 c        10433 g        19207 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgattt gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa tatttttttc
    14521 gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa ttttgcggat
    14581 ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct ttcaaccatt
    14641 tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct cctgtttcct
    14701 ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg atcacatcta
    14761 aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc gacaaatttt
    14821 taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact aattgttcta
    14881 aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca taaatttgtt
    14941 tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga acgagttcat
    15001 tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt gcaaacaatg
    15061 catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga atggcttcaa
    15121 acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga gcagcaggaa
    15181 cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa tacagggctt
    15241 cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg ttactgatgc
    15301 ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt cggcaatact
    15361 ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata gtggcttgca
    15421 tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt tccgtgatca
    15481 tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct tctaacagat
    15541 cgatttgaac caaagctgta taatagcagt cattttgaga actataacca aattgctgca
    15601 accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt acaaatagcg
    15661 tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt tctcctatga
    15721 tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct tttgatttaa
    15781 gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa aataagtagg
    15841 aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg attctcagat
    15901 tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc caattattat
    15961 aatctgattt cagtactata tacgttttat ctttttctct tatcactttc agctgattgt
    16021 aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact gtctgagtag
    16081 taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt tcaccaacaa
    16141 cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt tctttttcaa
    16201 acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa aataaattat
    16261 ttttgttatt tatgtacttc tgttgatact tttcaacttc ctcttcggtc agttgactca
    16321 acgatccatt gattactccc catttaccag ccaaactgac taaatcataa ttattatcat
    16381 ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa gtggagtaat
    16441 ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa ccatacgtag
    16501 aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact tgcctgagca
    16561 aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc tggtaaatga
    16621 ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa aatattttat
    16681 aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa aggctttcat
    16741 ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc aagaatagca
    16801 taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat atcaaagatc
    16861 tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt gaaaaagtaa
    16921 ggaaaatgat ggaatggtaa cgatcaaaga tatcgctaaa gcagctggcg tttctcatac
    16981 gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa aacaaaaaat
    17041 acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag gtttagtgaa
    17101 tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa cttcatcaaa
    17161 tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt acagtttatc
    17221 tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct acgatggact
    17281 gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca aagaaaaaga
    17341 atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca acgtcactgc
    17401 cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg gacatacgaa
    17461 gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg aaaaaggggt
    17521 attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt taacaggaga
    17581 ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt ctgacctgcc
    17641 tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag ctgtacattt
    17701 agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt ctccagtcgt
    17761 ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa tgtgtcaaga
    17821 aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat ctaaaattga
    17881 gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta caagtaattt
    17941 tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa aaaactgaca
    18001 aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg tgaaggcaat
    18061 tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca attgtttaaa
    18121 ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat gaaccagcaa
    18181 gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt tgatacttcc
    18241 gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga tgcttatcta
    18301 tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga ggcaggaatc
    18361 caattcgtgg agactgataa tttaacagat actcccccac agagcttccc gggcaaactg
    18421 acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat cattccttgc
    18481 gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta cgcagaaaaa
    18541 tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt ctgttgtagt
    18601 ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt caatcaacgg
    18661 cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg ggtgatcgaa
    18721 gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa tgtcatcatc
    18781 acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg accgcataca
    18841 gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt aatgaaagat
    18901 cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc tatgctttct
    18961 ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt cttgaatcct
    19021 tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt cagcacccgt
    19081 ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc gttaatcact
    19141 gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc acatgatgat
    19201 gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc tattcctcga
    19261 ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa tgtgacagat
    19321 acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt attacaagaa
    19381 atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat taaatcgacg
    19441 agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga cgattgatca
    19501 gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat tgggtgattt
    19561 gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga cgacagacgt
    19621 aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg gtgaattgga
    19681 ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc gaacatttca
    19741 aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt tagtacctac
    19801 cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg aaaaacatcc
    19861 agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct gttcgcagct
    19921 tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc atcccaatgc
    19981 cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg aattcaaaaa
    20041 aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag atgtttacga
    20101 tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg aaaatgacca
    20161 gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg gttctgatgg
    20221 tctatcggga ataactgcta atcctttact tggtgcattt tctgactact tgattgctca
    20281 aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac aagtattgat
    20341 ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca atgacttcaa
    20401 acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg gtaataaagc
    20461 aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat caggaagctc
    20521 tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc ttagtttatt
    20581 gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg attgccagtt
    20641 ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa cggtcaaggt
    20701 atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta atgcaggcgt
    20761 cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa tcatcgctgt
    20821 agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg ccatttttaa
    20881 aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg aagatttatg
    20941 tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta ccattcctac
    21001 gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga aatttacgaa
    21061 aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta caaatggcgc
    21121 ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc tgattttgaa
    21181 aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct ttacagttgg
    21241 tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga agaaaatgca
    21301 gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg ccgtcgggaa
    21361 atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc agacgacttg
    21421 cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc ttcattccgt
    21481 ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac actactggaa
    21541 gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt agggcagcgg
    21601 atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga catcttacgc
    21661 tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg agctaacaaa
    21721 ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca tttgacccac
    21781 ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg taactgtaat
    21841 acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa tgatctttct
    21901 ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca gttgccaaag
    21961 acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt gatgggctgt
    22021 ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta caacgatact
    22081 cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt ggggaatttt
    22141 gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga atatttccgt
    22201 cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc tgaagatgaa
    22261 caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa ttactttggc
    22321 ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata gtgaaataac
    22381 ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc gtcttcttct
    22441 cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac atgcctacta
    22501 tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt cccgagacag
    22561 gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat aaccaagcaa
    22621 agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt ctagcttcac
    22681 agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag aaaatccaag
    22741 aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata ttttttgaat
    22801 gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga cgagattact
    22861 tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg atgcgtgcat
    22921 ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa gaattgttcc
    22981 agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct gatacttgta
    23041 aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc gctgataaag
    23101 ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct aattatttac
    23161 aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga tttagatgtt
    23221 cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca tatccaattt
    23281 gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact tgggagtgct
    23341 gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt aggatgctat
    23401 atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac tttcaaacag
    23461 caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac cggtagtgtc
    23521 tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc cagaaattct
    23581 atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt tgaagcaggg
    23641 atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga agtagcttca
    23701 ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa tcatgctgat
    23761 caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac agcgcttcat
    23821 ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg caagggctgt
    23881 ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat gtacgccact
    23941 cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca gtttatttac
    24001 caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc aaaaatatca
    24061 tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc gttttgccat
    24121 gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga tcgctattgc
    24181 caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca tttatttcaa
    24241 cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt ttcatgtaaa
    24301 ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc ttatcaagaa
    24361 aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa tccagtcaaa
    24421 gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg tcagcggatt
    24481 aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa gtcctgttgt
    24541 tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct ttttccgtaa
    24601 aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt ctgcaaaagt
    24661 gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa aacacgaaac
    24721 aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact tagatatcct
    24781 gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc tgatttgttt
    24841 gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg tcgtgatgta
    24901 tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc tgattcctac
    24961 gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg ctggcgatgt
    25021 agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc gttttgagga
    25081 tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt ctctagaggt
    25141 gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat ctacactcct
    25201 taacttattg attggattta tccagccgac ttcaggaaaa atttttctag atgatcagcc
    25261 tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc ctcaaaccac
    25321 tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa acgtatcaaa
    25381 agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg accagcttcc
    25441 tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg gccaaaagca
    25501 acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc tagatgaagc
    25561 aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga attacctgac
    25621 agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag aggcagataa
    25681 aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa aactgttagc
    25741 tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag ctatgacaag
    25801 acttttgtcg tagctcctat ttctgaataa acggtgttct cctgccaact cctcggtcac
    25861 aagtcacaat agtcatcaaa catgagaagc tgttttttga aattgttcct tgtaactcag
    25921 agttaaacgg taggctcacg acctcttggt aaatggtgtt caagagacag cctatcggca
    25981 ataagaagca attttgtcat cgctcaaggc cgaacgtctc tttcacaccc tctgttgttt
    26041 cataaaatag ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga tacggttcaa
    26101 gtcattgatg attgtactga agccttgctc tttttgcatc aagtcattga ttacttcttc
    26161 tgattggatt ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc tgaactcttg
    26221 tccactcatt tgtttttctt gtaattcgat ttgcatcgct tggaagtctt tgaacagttt
    26281 gtgtgcttct tcgtttgctt gtactttctc gtacgcttct ttcaacgctt tgaattctgg
    26341 taattcacgg atctcacgtt cgatttgatt cgcgctatcg tagatgtttg acatgttatg
    26401 ccctcttttc ttttagtagt tactctctat tgtaacatgg ggttattcgt tttcaaaggg
    26461 gctactctcc ttgatatttc cgccagaggt ctttagccgc ttcaccaatt ccctgaacgc
    26521 cttctttcac catatcgccg aagtttttca gcccttcttt tgcttgttca ccatattgat
    26581 tcaagttatc ttgccaattt ccagactctc cattagaatt tcctgtgttt ccaacttgat
    26641 ctgcagctac cacttgtcct cctgtggcat aggcatctgc tacactaaat cctgtttttg
    26701 aagtatacgg aaggatgcct tctgccgctg atttgaagac tttcccgaca acatttccac
    26761 ttgtcccttc caaatagtgc agcttgctgg attcttcgta acccatccat gtcgaaatca
    26821 ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca tcgaaattag
    26881 tttctgtggt tcctgttttc cctgctatcg tataacctgc aggattcgca gcagccgctg
    26941 ttccatttga aaatgtacca agaagcatgc tggtcatttc atcggctgtt tcctttgata
    27001 tgacctgttt tggttttttg tttgtgttat cgacgatcac cgctccagtc gaatcaacga
    27061 ttttcgtgat aagatgcggc gtatacatct gaccatcatt ggcaaatgca ctgtaagcac
    27121 ccgccatgat caatggagat actccttttt ccagtccacc aagggctaag ccataatact
    27181 tatcagattt tgctaaaggc aggccgaatt cttctgcttt atcatatcct ttttgtaaac
    27241 cgatctcatg caaaagccat acagtaggca aattcaaact ttgtgcaaca gcttgataca
    27301 tcggtacttc tccttggtat gtcccgtcaa aattatgcgc atcgtaataa ctttgcggtt
    27361 cgtctttcaa gatactggaa ggcttgtatc cagcttccag tgctggtgta tatacgctta
    27421 atggtttgat cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg aatcctctaa
    27481 agacatgatc tcctcttcgt cctactagtg cttgtacacc acctgtattc ggatctaaag
    27541 ctactgaagc agattggacc atggcaccat ctgaagcatt tgctgggaat aatgcactgt
    27601 tttgataagt agcttctaat tgcttttgat aatcctgatc taaagctgta tagattttat
    27661 agcctttatt catgacatct tcttcatcaa gaccatactc gttaactgct tcatcgatca
    27721 ctgcatcaaa ataataagga taacgataac cagaatctga attatcgtat gtgtcattaa
    27781 gatacgcgct gatatctgtc tggctttctg cttgttcttg ttcttttgtg atttttccgt
    27841 tttcttccat tacacttagt actgtgtttt tccgatcatt cgcatttttt gggtgatcga
    27901 tcggattata aataccagga cctttcagca ttcctgccaa agtagcagcc tcagacagcg
    27961 taacattcgt tgcatctact ccaaaatact ttctggaagc gtcttggaca ccccataccc
    28021 cgttgccaaa ataggcattg ttaagataca tggtcaagat ttcttctttg ctgtacttct
    28081 tttcgatctc gattgccaaa aataattcct tcgcttttcg atcaaacgtt tggtctaatg
    28141 tcagatacgc atttttggca agctgctgag tgatcgtact tcctccgccc cctgatgttc
    28201 cgccagacaa gaccattcgg actgctgcac gggcaatccc tttgatatca aacccgtgat
    28261 gctcgtaaaa attcctatct tctgtcgaga ttactgcatc ttggatatag ggagaaatcg
    28321 cgtttaattc tacatatgtt cctttttggg cgtacagtgt gccagcttct tcgtttttct
    28381 tatcataaat gactgtcgat tggcttaatc ctgattttaa cgtttcgaca tttgcttgtt
    28441 ttgctaaaat aaagaggtag atacttgtca ctaagacaca gatcaaacca atcagcaaaa
    28501 tcaatttgtt cacatgatat tttttccaga tgcgctttcg ccatcgatgg aattgtccga
    28561 gatatggtct gatccaacgc caaaaactga tcaaagcagc ttttatcttt tctaaaatgc
    28621 tttgaaaatc catttgcttc ttctcctgtc tatttgattc aatcgtctta ttttaccata
    28681 gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat atgttttttt acgttagtgc
    28741 aagtagagta acataagaat gaacagaaaa atgtaagttt tttcttaaat atgttttaaa
    28801 aatggtacaa ttagtctgcg attgcactga aaggagtaca cttgtgaaaa tcacgatcac
    28861 tttacctatg aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg aatggttagt
    28921 tcctagaaag gttcgacact ttttgcgtat acgtaaaaac gtttggatca atcaacaacc
    28981 tgctttgttc catcatgaag taaagggcaa tgaccagatc acattgttat tcgaagaaac
    29041 agattataat tatcaagaag ttcaattagg agatgcgaag cacatccgtg ttttatatga
    29101 agatgagcat ttgattatag tggataagcc tgcaggaatg aagactcatc caaatgaacc
    29161 gacagaaaac agtaccttac tcaatcattt agctgcttat ctcgacacta aacagcaacg
    29221 accttacgtt gtccaccgct tggacaaaga aacaagcggt gccgttttat ttgcaaaaaa
    29281 tccatttgtc ttgccgatac ttggaagaat gttggaacaa aaaatgatct atcggagata
    29341 tcaagccatc gtatggggag aaattgccaa agatatgacc atcaccaata aaattggacg
    29401 agatcgccat gatcggagaa aaagggtcgt agatgataaa aatggtcaga gcgccttgac
    29461 acatgtcact gtcaacaaag tactttctga acaaacacaa gtctattgtg ttttggaaac
    29521 cggacgtaca caccagatca gagttcattt agctcataag ggacatccga tcgttggaga
    29581 ccctctctac caaaatagaa cagctgaacg actgatgctc catgcattag aactgcacat
    29641 gatccatcca tttactcaag aaaaaatagt cggtaaagct ttacctggat tatgggaata
    29701 gaaataaaaa agaacagagt cttatcagca gataatgata agactctgtt ctttttgtgt
    29761 aatttgtctg cttacttttg atgttcgtgt tctgctaaca gcaaactacc gataatccca
    29821 ctttcattcg gcagtcccca acgaacgata tattcactta cttgaggtgt ttccatataa
    29881 ccacccatca attcaacaaa ttgctgacgg attttttgaa ggagatgatc ctgattcatt
    29941 accccaccgc ctaaaataat cttttcaggt gctaacgtca acgtatagtt gatcagtgct
    30001 tgagcaatat aataagcctg aatagcccaa acaggatgat cttgcggcag atcttgccct
    30061 ttgatccctg tgcgtgcctc aatagacggt cctgctgcta atccttctaa acaatcttta
    30121 tgataaggac aagtaccttc ataatggtca tctggatggc gtttcaccca aatatgtccc
    30181 atttcaggat gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc tgcaccgatt
    30241 cctgttccca cggtaaggta aatacaacta ttttttcctt gtgctgctcc ttgcttcaat
    30301 tccccatatg cagcagcatt gacatccgtt gtccaagcag caggaatatt gtagcgttcc
    30361 ttgattgtgc caagaaaatc gaattgtgcc cacccttttt tgggagttgc caaaacgtat
    30421 ccgtaattat cttttgtttt gtcgatacca atcgggccga atgagccaat cccgattccc
    30481 ttcaattcat aacgatcaaa aaattcaaat acctgatcca atgtttcttc tggtgttgtg
    30541 gtagggatac ttaatttttc taaaatttct ccaccatctg aaaccgcaca cacaaatttt
    30601 gttccgcctg cttctattcc gccatacatt cgttttcctc ctcgaatccg attgtccgaa
    30661 tctcataagg ttggattatt gggacaaccg cttgcttcgt tggttcttca agcagattca
    30721 atatgacagt ttttccattg tctttagtta tttccaattt ttctaaatga ctagacatat
    30781 tgaaacctct tactactact ttatcactaa acttgctgcg tttcaaagct gtaattgcaa
    30841 acgtttcact ttttatcgtt aaatattgtt gttttgaaat caatgttcct tcatgatgtt
    30901 tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa gtagagaatt
    30961 tttcttctgg tccatgtagt tcaatgctgt aattgaaccg atgctcacct agacactgtg
    31021 cttctggtgt tggaaaatat ccccaatcgc ctagttctcc cacactgcga agtagcgtca
    31081 ctgcgatttg tccgtcttct gttacttcat attcattcaa accaaagttt ccgactgtta
    31141 caccgtactc ttcatcatga atattgacaa atgcttgctg atgttgcgga ttcgtggggt
    31201 tttcccaact tttagacaca tggtttgggc gcttcaccac ttcaaaaata ctatctgctt
    31261 cgtgatgttc cacatgtaac tttgtaggaa acaagacacg taagcgatga tctttcatct
    31321 gattgtcgag agtcgtttca aagtcgattt ttttactatc ttttctgatt gtcatgattg
    31381 tttttatttg aaggattcgt ttttctttgg atcgttctgc ttttcgataa cgaaattcca
    31441 caaccatctg ctgttctttt tctaaacgct cgtctgcaga aacagggatt tccatttcct
    31501 gtagaatact tatttttgct atttccggtg tatctactaa tacttttact tcagagtttt
    31561 ctttgttact ggataggatt ggctgatcac agaaaggttg tttaaagata tactcatttc
    31621 ctatatcgcc gatatcttca aaaatatgca gattattcaa ctttcgtttg tttttgcgat
    31681 cttccattgt aatggtacca tttttttcaa tcgtcaaatg tagagggccg ttttcgatga
    31741 ttcgtccact ctgatgaatc attgtttcct tttcttctgc tttcgcttcc ccttctacaa
    31801 gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa tggtaaagtc actttgatca
    31861 ttcttgccat atatggcaca cggaaacggt ctttcggcaa atcataacca aattggacag
    31921 tttcttcaga taaaatagct ggtatagtgg ccccactttt tgtttctaca tgatacttac
    31981 gtttaggcaa attttctaac tcttgatata gttgttcagg tattccttca gcgaatcttt
    32041 ttctttctaa ttcgatggtt atttctgctt caccagtttt atccattcct gcagtattta
    32101 caatgacaaa tggaaagctg tcttttggga atccggtcgt atcgattgct gcggtcagct
    32161 gttctaagga atcttgtgca agatactttc caacttcatc tgctttttca aaacgaggta
    32221 tcatttcccg atggacagaa tcgactgaac aaccgcaaat actgtcgtga ggatgatttt
    32281 gcattaatgt cttccaagca taatctaatt gatcatgggg atagtttcca ctaacttcat
    32341 aagccatcgt cgcaagtggt tctgtaatat tttctagctg tcgctggacc ttggtattcc
    32401 attgttttaa gtaaacccga gcagatgctg tattggctaa agtataccag ccatccgttt
    32461 cttgacttgt caattctcct tctactgagc ctaagtcttc tggcacatct ttttgaactg
    32521 cttccagata gtcagtaaaa ttagaatgaa taaactcgta atctggaaac agttcatttg
    32581 cgagatggat tgcttttgat atatcttttt gtaccggttg atgatcaaca ccattcatca
    32641 tcaataagtg gttcgtagag gcatattgtt ctgcatccgc taatttttgc ttccaaaagg
    32701 caagagctgc ttctttttct actggaatct cattcccgtt gctataccaa ttggcaaata
    32761 gcagaccaaa gattgctgtt tgatcaggtc ctttccacca catctctgag tattgggaag
    32821 aatagttttc tgcttccaaa acttgattat caaagccaat tggttttaca ccacggccaa
    32881 acgctgctgc tgaaatacca gcttgtttca ttaattgagg cgtctgtccc atatttccaa
    32941 atgtatcggg aaaatagcct aacatgacag gggttcccca tttacggctt tcttccatgc
    33001 caatcagcat atttctcacg ttcgattccg agctgataag aaaatcatct tgcaagatat
    33061 aaaatggtcc aattctcaat tttccttcat tgattgcttg ttggattgcc tgtctttttt
    33121 ctggccttac ttgaagatag tcatctaaaa taatcgtttg cccatccaaa tgaaaactgt
    33181 tgaaggacgg atcaacttca aatagctcta gtagatcgtc tatcaattca atcagtcgca
    33241 tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca gtggctatga gaaatgatat
    33301 atactttctt tttcatttac gatacctcct acttttctac tctaatatca aagtaatcca
    33361 tgactaattc gcaaaacatc atatttgccc aagaaaacca ttctctcgta taattttcag
    33421 gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt gctacaagta
    33481 aattcaatat ccgctctttt tcagatttgt ctgacgttgt cattccttcc atagctaatg
    33541 caatcggcca aacgtatttt tctggcgtat gggaggatcc aattcctttt gcgtactttc
    33601 cttcatagaa atatggattt tctttactca acaatgttct tcttgtttgc agataatctt
    33661 cctcttgttc agaacaatat cccaagtaag gtgcggcgat cagattgggc acattactgt
    33721 catccatgac tgtggcgttt cccattccat ctacttcata tgcataaatc gtttgccctt
    33781 tttgattaac cgttcgtccg tgattctgaa tcccctcttg gatctctttc ttcaatttct
    33841 gtgtttgctg tacaatttct ttatcatcga gtatcgtttg aaaaatttct tccacataac
    33901 ctaacacgac caccgcaaac atattggatg gtaccagata tccataacgg caagtatcat
    33961 cgctaggacg gaaaccagac catgtcattc ctgtaaaagc tgtttttgca cctcgcccgt
    34021 cattgatcag cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa ggagagtgtt
    34081 catgatcttg ctctgttttg aacacgtcca agattttttt gataccttca ataaaagatt
    34141 gattgaattg atcagttttt cctgtatttt tgtaaagaag ataggccaac tgtattgggt
    34201 agcataaaga atcaatttca tattttcttt cccagatcca atcgttcatt tttgtatgat
    34261 ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc attcgcatat ggatcgatat
    34321 tgatataaaa aaattgcttt ttgactaacc cgctgatcat gtcagctaat tcctcatctt
    34381 cttttgcaat cactaaataa ggacgaactt gtgcagtaga gtctcttaac cacatcgctg
    34441 gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg ctttttgact gttgtcaaca
    34501 gagtattggc aaatgctgct gtaaaattct ttgcccagtc cgcatggata tccccacatt
    34561 tttgtgtgat atcttccata aatttctgca ccgattttgg tatatcttta taagccacta
    34621 ataaaacctt ctttctattt gatatatctt taaagattat acttcataca gccaattatg
    34681 tctacgcttt caaaaaatat ctttttattt actttttcat ccattatggt attatttgaa
    34741 tatgatatat cattaagagg tgtttatatg aatcaaccat tgtaccagac aatatttaat
    34801 gatttgcaaa cggctatttt aactggtgaa ttacctgtag acagccaact accaactgaa
    34861 aaagaacttt cacgtaccta taaagtaagc agaatcactt ccaaacgtgc attgactgaa
    34921 ttagagcaat taggacttat ttatcgcgtt cgcgggaaag gcagtttcgt taaatccgct
    34981 tctccggaac agattcttgc ttctcctaca aaaacacgac ggattctgtt tcttcttcca
    35041 tatgtcgctg atttgtctgt tggtgatttt agcaagggat tgaaccctgt gatgcaagat
    35101 aaacagattg atgtcatgat gacgacgctt gactttctac aaaataaaac agcaaaagag
    35161 ctaatcaatg aatttgacgg attgatttat tatgctcttg atacagaaca acatcttgac
    35221 ttactttttg agctttcatt gaaagaattc cctgtcgtca tattagataa aaaaatctat
    35281 gagttacctt ttcctaccgt tctttccgat aatttccaag gcggtgcgct tgctgcctct
    35341 tatttgatcg aacagggaca ttcaaaaatc gcttatttgt ttggtacgca gactcatcca
    35401 caatccgttc gacagcgtta ccttggttac cttgaagcat tggacaaagc tggtttgact
    35461 ttccacactt cactggatga caaaagcgcg acattagatg aattgctttc ttatatcact
    35521 aagtatgaag taactgcttt tgtttgtgaa aacgatgttg tcgctatcca gaccatgaat
    35581 ctcttgagac agcatggtta tcatatccct gaagattttt caattatcgg atttgatgat
    35641 atccaagcag cagctcttgt tgacccgcca ctgacaacca tcgcacaaga ttttgaacag
    35701 ttaggtaagc ttgcgggaga tgctttggtc acttggttag agacaaaaga tcgaccatcc
    35761 gatagtaaat ttccagtttc attcatcaaa agacaatcaa caaaggagaa ataaaatgaa
    35821 tatcggtcaa atagatacta gacatgcaac agcgaatcag ccaaatttct ctaatgggaa
    35881 ctgccagcct tatactggcg ttccttttgg gatgaattat tttgcaccgc aaactacgga
    35941 tcaaaacggc agctggtggt ttcatcctga tgaccgcgtt tttcaaggct accgtcttac
    36001 ccatcaacca agtccttgga tgggtgattt cagtcatatg ctgtttacgc cgatcaatgg
    36061 aaaactacag gagaacaccc ttttccatgc tcaaagttct taccgcccag aagaaagtat
    36121 attttgcccg actcatctgt cgatctgtca attacgttat ggcatctgtt ctacattgat
    36181 acctagcatg tatggcggaa tcttatctat tgattacagc aaaaatgaca gcggtttact
    36241 tttatccttt ccgggacgcc atcagctctt tgttatagat ccttacacag tggaaggaaa
    36301 aatcacacat tttgctggtt cagaagatcc tgatttttct ttttatttta tattgagatt
    36361 tgaatatcct ttaacaattg atgagttagc tgtttccaac aaaaatagcg actcgatccc
    36421 gttgtatttt gaacagacaa aaaaacaaac tatccgattt gggacatctt ttatcagctc
    36481 ggaacaagca gcttataacc tggaactaga acaaaaccaa agcaaagaga cttaccttgc
    36541 tcacagtcaa gaacaatggc agtcctattt tgatcgtata cagctcacac accatgatca
    36601 acaacaattg cggacgtttt atcataattt atatcgggtg tttttatttc cacaaacatt
    36661 ttatgaaatt gatcctagtg ggcaaaaaat ccactatgat acgactagtc gatctataaa
    36721 acctggtgtt ctctatacaa ataatgggtt ttgggatacg tataaaacgg tttatcctct
    36781 ttattctttg attgctgtag aaaaatacga agaaatgctg gaaggttttt tgaacagcta
    36841 tagagaaagt ggctatttgc caaaatggct gtctcctgat gaacgtggac ttatgcctgg
    36901 gacattgatc gatgcggtca ttgcagatgc tgctgtaaaa gatatccgac gagacttgat
    36961 gcctgaattt ctaacggcaa tggaaaaagg tgctacggtt caaagcaaac atccaaatta
    37021 tggacgccaa ggaacagaag attacttgac atatggctat gttcctaatc actaccacga
    37081 atcagtcaat cacacattag actatgctta tagcgatttt tgtattagcc aagttgccaa
    37141 ggtactagaa gaagaggaaa tgacgaagaa atatcagcag caatcattga actatcaaaa
    37201 tatctttgac tatgagtcag gatttatgcg ttcaaaagat aaagatggca agttcagaga
    37261 accattttca gctaatcgtt ggggacaaga ttatgcagaa ggaagtgctt ggcaaagcag
    37321 ctttgctgtt tatcacgatt tttcaggact gatcggaaaa tatggtggca gtgagagata
    37381 taaagaaaaa ctcattgagc tgtgcaatca gcccccaacg tttgacccag gaggatatgg
    37441 ttttgagatc cacgaaatga gtgagatggc cgcgatagaa tttggacaat tagctatttc
    37501 aaaccagcca agttttcact atccttactt gttcagttat ataggacaac ctgaaatggc
    37561 acagccactg cttaaacagt tgatgactca gaccttcgac gattctccaa tgggttaccc
    37621 tggagatgag gacaatggaa gtatggccgc ttggtatatc ttcaatagtc tgggatttta
    37681 tcctgtcacg cctggaaccg gtgaatatgt tatcggtatg ccattaattg acaaggctgt
    37741 tttgcttttg tcaaatggaa aggaattgac gattgaagca acgcctaatc ggccgcagca
    37801 acaatttatc cataaaatca aacggatgga caaagaatat acgaaattat attttaccca
    37861 tcaagatttg ctgaaaggcg gcacgatctc ttaccaatta gggatcatcc ctcaccctaa
    37921 gaaatatcaa gcaaaagatt tgcctttttc cttatcaaac tataattaac aagaggttgt
    37981 gaaaaagctg tcctgcatca agtaataaga acagccaagc aaaaatagat cctcatattt
    38041 ttcgtttggt tggtcttatt accgcagatg caagcttttg aacaccgttt attgagaggt
    38101 tgtgaaatca gcgttctgac ctgagtatta gagagacaaa tggcaaaata gttcctcata
    38161 ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagag
    38221 gtcgtgaaaa agctgtttag tttcgagtat taagaaaaat tttgtgaaaa tggctttcca
    38281 catttttgca taaatttggc ttaataccga gaaactggct tttgaactcc gtttatcgag
    38341 aggtcatgaa aaagctgcct tgcctcaagt aataagaaca gcccaaaatt agatttctag
    38401 acaatttttt ataagttatt tcattacatt ggctttttct tttatgattc tccactgttt
    38461 tctcggtact ctttagggga tctgccgacg attttcttga ataatttaga gaaatacgtg
    38521 gtgttgttgt agccaatctc acttgctatc tcattgatgt tttgattact gtgcaaaagc
    38581 agttgtttcg ctttttccat acgtaaatgg ttcaaataag ctgaaaaact ttttttcgtt
    38641 tcttttttga acagctgtcc tagatacatg acatttaaat gcaggttttc tgacacttct
    38701 ttgagtgtaa gtggttcttg ataatgctgg tgcaggatta cgattacttt ttccacattg
    38761 tcactgtact ttttctgtct ctgatgcttt ttgatgaatg acagaagtag ctgctgaagt
    38821 tcttgcaccg tttttgcctg atggattttt tcgattcctt gtaaatattc ctcatcttcc
    38881 agatcaatca attcccgttg aatctccata aacagtaaaa aactggaata tcgtatatct
    38941 tccggcatca tggctgctaa ctgaaactgt tcaaaaaaat cagtgatcat tttttgagcg
    39001 acttccaatt gtttattttg cagcacgcgt ctgaaacttg aaaaatcgat ggtttgatct
    39061 tttgtttctg cttgtactgc gtaaaaaaca tgctcgtctt tatctccata aaattgatgc
    39121 aactgtagat tgtctttcgc ttgttggaat gtttcaggga ttttgtccaa agaatctgtc
    39181 tcttccccga tactgatcag ccattcctga tcaggaaagt tttcttgaac aaaacaacag
    39241 aagccatcaa cttcatctgc ctccaacaac aacgtgatca atacacggtc tccgtaattt
    39301 cgttgatagt aaaagatttg ttgccgttct tgcaaccatc tattgataag agtatcatga
    39361 gttcttgcca gttgaatcaa tactatccta tgctgcttct cacttatttg tcctattatt
    39421 tcttcttcac ttatttcatc caattcttca ttcaaccatt gactgaataa cagttcttga
    39481 tagatttctt gttgattttt ttgttcattt tgctgatcta accgtgtttt gattttcttg
    39541 aggctttcaa ccaattcgaa cttattcacg ggtttcatca aataattcac ggcgcctaat
    39601 tgcatacctc ctttcaaata atcgaattct tggtatcctg ataaaatcat aaattcaaaa
    39661 ttatgacgtt ctttttgagc cgcttcaata aattccagtc catttatttc tggcattgtc
    39721 acatccgtta ctactaaatc aatctgtcgc tgttcaagta cagctagtcc ttctttggca
    39781 ttctctgctg ttgctactat ttgaaagcct aaactttgcc aatcaattat cttttttaac
    39841 ccattcaaaa tcatgtattc atcatctacc aataacactt gatacacgct catccctcct
    39901 tgaatgtaat agaaacggtc agtccacctg tctcattatt ctcaagcgac atataataac
    39961 tactgccgaa gctggcacgt aaacgttcat tcacgttttg cagaccgata gaaccgtgaa
    40021 gttccacttt aggatgagac agtttttctt caatctgttt tagccgtttt tcagtcatcc
    40081 cttttccatt atctttgatg atgatcctta cccgtttgcc ttcctgcaag actttgacac
    40141 ttagcgcatt atcgaatcga gtaaaatcaa taccgtgttt aaaataattt tcaactaatg
    40201 gctggatcac aaatttaggt acttcgatct tttccaaatc aggatcgatc ataaaatgat
    40261 aggctactcg attaggataa cgcatttgat acaaatagac atatttttcg caaaagtcca
    40321 gttcttcttt taaagtgatc gttttctctt gattcgtatt gtttcgaagc aaagcggaaa
    40381 acgcatacac aacatctgct aattcttcac ttccttcgct gattgcatac attcggatat
    40441 attctaatgt attatataaa aagtgtggat tgatctgtgc ttgaagcgcc cgcatatgtg
    40501 cgtcttgctg tttgatttct aatttgtaga tgtcttctac aaactgattg atgctatcca
    40561 acatttcgtt gataccgatt gaaagttcct tcagttcata ttccgtgttt gttatgtcga
    40621 tccgcgtctc taaattccct gctgctgttt gatccatggc ctgcatgacg atagatactt
    40681 gctgtgaata tcgtttgaat gttttataaa gaaagataag cagtatattg tctaaaataa
    40741 tgataccaat gatcagcggg gcaagatttt ttcccgtttc gatttttaca ctttttttat
    40801 ctagtacagc taatatacga taatcatcag acagttcttg gtgttgaaca aaattgtttt
    40861 tttccagatc gtcaatcggc aattgtgaat ttttcttcag actctctgtg atgatcattt
    40921 cttgtctttc aaacgtttct ttagctattt tattatcatg gaatgtgtat agtcgatttg
    40981 tcgttccaga aatcatgtat aaagagagtc cattgaatga cgttagattt tctaaaatca
    41041 tatctagttc tttcttttga aaaccaataa aaatacttcc tgactcagct cctccttgtg
    41101 tgataggcaa cttgatataa aaggcgtcta gtaattttgg tgtccccttt tttatttccc
    41161 cacctttgtt ttctctagaa gattcataat actccggtag ttgattcaac acgatatata
    41221 tcgcacttag ttcttcataa tttgcgtaga gatctttgat ttgatttggg aaagaaacta
    41281 attcatcggt actgttttgc tgttcgtata catacatcag atactgatct atgggttttg
    41341 ttaagtaggt cgtcacattt tcgatctttt cggaattccc tacaagctgg tttttgatga
    41401 tcctactcaa ggttgtttta tcattcagca ttctgcttgt gctttgaacg gcatcacttg
    41461 tcatgttttc tgcctgtttt tgattttgtt cccaagtatg gatactaaaa ataacggtag
    41521 cagtcatcgt tacaccgatc atgataaccg cgtatttccg caacagacga tttagtaagg
    41581 ttccttttga aaatagaatc cgaaacttat tcataacttt ccaactgttt atctaattct
    41641 tcacgccaat gtgttgtcat cgtaccattc caaaccgtca aaagaccaat gacaccaaac
    41701 aggatcaatc ctttgaattg ccaagtcacg cctaaaatta taccgctacc aataattatt
    41761 tttagaaaag acgaaaagct ggaaaaaacc gaaataaaac ttagctttag cagattagga
    41821 acagagatcg tatattcact atctaaaatc atactgtatt gataagtagc aaataggcag
    41881 agcaaggcaa aaagtaaaat aaaatcaata gctaaaaaaa tgagcccttt gatttgaaca
    41941 gataaatata aattgtaact caataaagca gtaccagata aaaataaact aaatagcaga
    42001 ttgcctctta aaaaatttct tttatatata ttccagcctc tttttattgt gatttcttta
    42061 tactcgaatc cgtacaaata aaatagttca ttgactgttt tccatgccgc acctaatcca
    42121 aagatgatcc cgccggcaaa tgtatatatc cagaaataca aggttagttt tataatgacc
    42181 cagatccgga taaataactc ttccaaaacc ttccctaaca tatcttctcc tccaaacatt
    42241 aagtttatac tttctcatta tacaaaaaaa ggttgggcaa tcagcacctt gacctgatta
    42301 ttagagaaac aaacggaaaa atagttcctc atattttgtc gttttgtgag cgaataccga
    42361 gggttagctg attgaacacc gtttaccaag agtttgtgaa atagccgctt agtttcgagt
    42421 agtaagaaaa attttgtgaa tatggctttc cacattttta catatattta gcttaatacc
    42481 gagaaactgg cttttgaaca ccgtttattc ggaacaagag gttgtgacac gtcttttgtc
    42541 acaacccctt tgtctttatt cattattatt cttgtcggaa ctcatcatat tgtttttgca
    42601 tttctttcaa taccttatca tagccagcct tgtccaaagc gtctttcaat ttcggtaatg
    42661 tttcatctgg atcaacagtc cctgtattca atccatctaa atattgattc atgacattag
    42721 aaatattact taattctgtt ttgacactgt cagtgttgaa gctgaatcct aaaatcggtg
    42781 aagtttctgc atcagcaatc gattgatcac gtttggcaat catgtcatcc gtaatagact
    42841 cttgtgtata tagaatcttg ttgtttcctg tattccaagc agacatatgt gtatttggct
    42901 gataaccatc tagcaatttg attttatcat ctgaaccatc gactttttcc catgcttctc
    42961 cctcgatccc ccaaacaagc ccattcaata attctggatc actgttaagc agccctagaa
    43021 gttctactga tttttcttta ttttttgaag tatttgatac gacaaaattt gccatttgtg
    43081 cttgagctgt agattttagt ggaacagtaa ttgcttttga gacaagttct tgttttgctg
    43141 catttgtcaa aattgtatcg ccataatcat acggtccttg tgtttctcca cgcattagcc
    43201 aagtatttcc ttctagtgga taatccttat tgctcgttgc agcgtcactt ggaatgagtc
    43261 cttgtttgta ccagctatgc attgtacgta acagtccgat atacgtttca ttatcgtatt
    43321 ggttgatgat tttcgaatca tctccatcca gatcaatagc aaatggtaac gtattcccta
    43381 aaggataatc aaagttccct tggactttga agccttgtcc aatggcaaaa gctgccgtgt
    43441 ttggttcttt ttcatggaat tccttcaaga ctttttctgc atcagcgtaa gattggattc
    43501 catcaattga aagatcgtat ttatctagta aagctttgtt aaaagtaagt acttgttgag
    43561 caaagacatt tccattgact gggaaagcat ataattttcc attgaccaga tttcctttaa
    43621 tatatgcttc atctaaatca ttataagctt tttcagcgta cttaggcgct aattcagtca
    43681 aatcagcaaa ggctcctttt tgggcattgg aaacatagtt gttcgcaaag gcgatatcat
    43741 aattttcccc ggaagaaatg atgacgttca ttttcttttc gtaatcgccc cagccaatgt
    43801 aattgatatt gacttttaca ccgatctctt tttcgattcg tttgtttgct acttccatca
    43861 attgatcgaa attatctggt ttatctccga tttgatacat ctgcaaagtg tccgaattgc
    43921 tagcttctgc ctggtcttta gaaccagaac ctccgcatgc tgctaatgtt cccaacaaca
    43981 acgctgaaac acctgtaaag gctagtttct tccataactt catttttctt cctcctaatt
    44041 ttatgattta tatttttgtt tctttattct tttactccgc cgattgttag acctttgaca
    44101 aaatgcttct ggaaaaatgg atagctgatc gcaataggca acgtcgagat gactacgatc
    44161 gccattctgg cagattctcc tggaactgag gctaatccgc ctgtcaattg gcttcctgct
    44221 cctgaatttt gtgtcagata ttgaatatta ctttggattt tcatcaaaag atactgtagt
    44281 ggaactagct tatcatcttg gatgtatagt aaagcattga accagtcatt ccagtaaccc
    44341 aatgcggcaa ataaactgat tgtcgcaata cctggaacag ctaacggtaa aacgatctga
    44401 acaaatattc gcagttcgct agctccatcg atccgtgccg attcaataat cgaatcagag
    44461 accgaacgtt taaagaatgt gcgcatcaca ataatattga agggactgac agccattggc
    44521 aagatcaatg cccaaatcgt atcttttaac tgaagaagat ttgtcataac aagataattg
    44581 gccaccatcc ctggtgagaa caacatcgta atcaaacaaa aaacggtaaa aaaacgacgg
    44641 aatggaaagt ttgaccgtga aatcgcataa gcatataaag aagtagccgt gctattgatc
    44701 agtgtaccta aaacagtaac aagtacagtg acgaaaagcg cttggaaaat tttatcctgc
    44761 atctggtcga acaagtacgt ataaccaaat atactgaact tttctggcca aaaactgtac
    44821 ccgtgagtcg acaatatgga ctcatcggta aaagagatgg cgataacaaa tataaatggc
    44881 aaaatacagg aaatagcaaa gagtgcaatc attatattag agaaaaaatt agccgtctta
    44941 ttgaaagagc ggacttggac tctctccact ttcttttttt tcattttttt cctccttaga
    45001 ataatgcaga atcgctatca aaacgtcggg cgatcgtatt tgtgatcatc aacaagacaa
    45061 agccgacaac tgattggtaa agtcctgcag cagccgtcat accaaaatct cctgtggatg
    45121 tcaggccatt gtagatatac gtatccaaaa cttgagacac atcatataat gcaccggaat
    45181 tcctaggaat gttataaaac aggccaaaat cagctcggaa aatgtttcct acggctaaaa
    45241 tcgttaaaat cgtcattagt ggaataagtt gtggtatcgt cacatgtttg atctgctgcc
    45301 atttgctagc tccatcaacc atagcagctt cataataagt cggatcgatt cccataacag
    45361 atgcaaagta aataatgctg ttataaccaa tccctttcca tgtaccaatg aacaccaaga
    45421 taaacggcca atatttcggt tcattatacc aattgacagc ttctcctcca tgtccagtga
    45481 tccactgatt gaatattcct ttgtcaggac ttaaaaaagc gtaaacaaag taactgataa
    45541 tgacccaaga tagaaaataa ggtagtaagg acatcgtttg ataaacttta acgagtcgtt
    45601 tatttctcaa ctcgctcata atgattgcaa atacgactga gatcagcaga ttcaaaagga
    45661 taaatgctac attatataaa attgtatttt tagtgatgag aaatgcttga tccgaagaaa
    45721 ataaaaattt gaaattttcc caacccaccc aaggactttc cctcaagcta gccaagaacc
    45781 catctgctga aatatgaaaa tttttgaatg ctacgacatt cgccattaca ggtatgtaaa
    45841 agaaaaaaat catccaaagc atacccggta cagccatcag gacaagtgct ttataacgcc
    45901 atagattcat aaaaaaatga ttgaacccct ttcgtttttt catctaaaaa cccctttcga
    45961 ttcattcgca acgtaattat agcgctttca ataatgagaa taaataaaca aagtataggg
    46021 aaaatgaaac aaagtatagg agaggttgtg aaatcagcgt tttggcctga gtattagaga
    46081 aaaaaacggg aaaatagttc ctcatatttt gccgtttttt gagctaatac cgagggtcag
    46141 ctgattgaac accgtttatc agaggttgtg aattcagcgt tttggcctga gtattaggga
    46201 gatcgtgtcc ttactatcta actctgagtc acaaggaaca atggggactg taacaaaagt
    46261 cttgtcacag tcccttattc cgaacaaacg gtgttccaga agtagcttct acggaaataa
    46321 gccgaaattt cacaaaaaag ccatccgaaa gtcagacgga caagtctgct tttcagatgg
    46381 cgctacaact actctgctta ttcttttagc tatccattca attatttttc tctcacttgt
    46441 tctagctctt ctttggtcat gggtcgatat tgccctttat tcaaatcttt aggcagccaa
    46501 aattttccca tacggattct ttttaaatat aagacttctt ttcctactgc tttgaccatt
    46561 cgcttaactt ggtgaaactt tccttcatgc aaaatcagac ggataattga agtttctgtc
    46621 tcttgatcta cttgatcaat ttggagtttt gccggcaatg tctgctcatc gccatcaata
    46681 atcagtcctt ctgcaaataa acggatatct tcttctgtca ttataccgct aacctcagct
    46741 agatattctt tctccacatg ttttttaggt gatagtaact gatgggcaaa caccccgtca
    46801 ttcgttaaaa tcaagaggcc ctctgtgtct ttatctaatc ggccgactgg aaaaagatct
    46861 tcccgataat cctggtcttc caataaatcg attacggttt gatcatgatt atcctgagta
    46921 gcagaaatga ctcctgcagg tttatgcaaa atgtagtaaa aatctttttg atacgtaatg
    46981 atttctccta aataagtaac cgcatcttcg aattcattta cttgcgcttt atcgcttttc
    47041 accacttgtc cattgacttc gatcgttcct tttttgatta atcctttgac ttctttgcgg
    47101 ctgccaagtc ccatatctgc taaaaactta tctaaacgca tgcgtttccc ccatttcaaa
    47161 agagcatcaa tctagctctt ctgattcact tattttattt ttaatttatg tcgtaaacgc
    47221 gctattcctg gtcctagtag tctttctgcc aagcggattt tcaaagctaa ataaccatac
    47281 actaaagccc ctatacctgc tactacaaga atcaacaata gagactggaa tttgctatct
    47341 tcgtttaaaa aagcaccaaa aatcatcttt gtgatccacg aagccaaaag cataatcaag
    47401 gtaagaataa agatcagcaa tgtcctgcgc cagacaaaac ttggtttaaa gcgggctact
    47461 tcatggattc tctttaagat caaggtacaa gacacagcaa atccgatcat tgtcgccaat
    47521 aaagggccgt atacttcaaa taaacgaatg gctgggtatt gaagaaggag tttcactaga
    47581 aacccaataa ccaaataatt aattgccgcc ttgttttcaa acattccttg cagcatgttg
    47641 gaaactagca tatatagtcc taggaagagt cctacaaaac ttgcttggat cagtacatta
    47701 cttcctagag aatccggtgt ataaaataat gtatttagcg gataggcaag taacataaca
    47761 ccaaatgtcg ccggaaacat aaaaaatgaa aacaactgta aatttccgct tgtcaatttt
    47821 gccagaccta ctcgatcttt caacgtaaca gcttctgtaa tcaacggtaa cccagtagac
    47881 gcgatcgatg ttgccaatgc aataactacc atcgtcaact tatctggatt ggcactaaaa
    47941 atcgaaaaaa gatccagtaa ctgtgcattg gaatactcgg tggatgcaga catgatcttc
    48001 ataaaagtga actgatcgac taatttgaag atcgttaccc ctgaacccac aataataaac
    48061 ggaatcgctt ctttaacggt atctaacaac aattccttcg ttgcaatatt tattttgttt
    48121 tcgctgtagt gaataaacgc cgatgtatac gcttgatgtt tcttcaaaaa atacaaaagg
    48181 acaagaatac ttgctagcat accgataaat gccgcgaaag ttgattgcgt gaccgccgtc
    48241 acatagtcac catccatgac tttcatgatg atgaatgtag ccaatagcat ataaaaaata
    48301 cgtgccacct gttctacaat ctgcgacagc gcataaggca tcatttcttg attgccttgc
    48361 aaataccctc gtatcacact catacaagga aaaaccaata cagcgatact caaagaacgc
    48421 atcgttggaa tcagttcttc tccgccacca gaagcatgag ctagccaagg agaggcgatg
    48481 tacatgaaca aagcaaacaa caggcctaac ccgcccatca tctgtaatgc acggataaat
    48541 aatcgtcgtg aagtgccata ttcattcaat gaattatagc gtgcagtttg ttttgcaatc
    48601 gcagcaggta ttcctgctgt agagatcagt agaaacaatg catatatatt gtatcccata
    48661 ttgaataatc cattggcagc cttagcattt tcgcccatcc aagcatacca gggaatgata
    48721 tagacagcgc ctagcaatct tgaaatgata ttactggcgg tcatccaagc agagcctcgt
    48781 gccatttttt cttgcggtgt taattgatct aatgctggtt ttctttgatt atccatcggt
    48841 cagattccaa ctttctacaa aacattacta tcattttaat tggtaaaaca gaaactggca
    48901 atcgatttta tataactttt ataagaacaa ttgttttttt gaattcggtt tcgttttttt
    48961 ggtaaagtaa agaaatatac agccttttat ggctaacatt tataggagat atcaatgaca
    49021 caagaaataa aaaaactacc cgttatattt ttaggtcttt tctttatcac agttggattg
    49081 aattggttct tgctccctca cgatatagct tccgccggag tgggcgccat cggacattta
    49141 gttgaaacgg ccttttctat ccaacgctca gttactgttt ggagcatcaa tcttatgatg
    49201 ctgcttctag ccgctgtcct attaggaaaa tcagtatttt ttaagactgt agcgggaagt
    49261 ctgctttttc ctgttgtttt agagattgtt ccaaaagtgg aaatgatctc ctcacatttc
    49321 ttttcactga tttcaggaag tcttttgttc agtcttgggg tttacacatt gtacacagtc
    49381 ggggcctcaa atggcggtat aacgataccg ccgattattt tccacaaatt ttttcggctt
    49441 ccaatgccgc aaggactttt acttaccaat agtcttatcg tctttttgaa ttattatgtt
    49501 tttggattgt tggagacact attcgttctc ctatctatta cagtcagttc attgtttatg
    49561 aaaatactca tccgcttgtc ccctgtgtca agaaaatttg aataaagctg gattttgtca
    49621 tagcggaaac aaacgatata ttaaaaagag tgtgctataa taaaccaaga aattgaataa
    49681 agcgagggat caatcaatga gcttctcttt agaagacatc cgtcatttac tattaaaaga
    49741 aaatctatta aaagaatttg tttcaacaag aggctggcat cttgatgtac cagaaaaagc
    49801 tgaatttctt cagttaagtt atgattcaag aaaagctgat gcttctactt tgtttttctg
    49861 taaaggaatg aatttcaaag aagaatattt ggattcagca atcgaacagg gtattcaata
    49921 ttatgtatca gaacaaccat acgaaaattc agcagtagga atcatcgtaa cggatatccg
    49981 taaagcaatg gcgcttcttg ctatggcttt ttacgactat ccgcaaaata aattgaaagt
    50041 gatcggattc actggaacaa aaggtaaaac aactgctgcg tactttacaa aagcaatctt
    50101 ggatcacaca acaaataaaa aaacagcatt gctttctact atgaatacaa cgttagatgg
    50161 caaaacatat ttcaaatccc atttgacaac gcctgagtca ttagatttat atcgtatgat
    50221 gtcagaagca gttgaaaatg gtatgactca tctagtgatg gaagtttctt cacaagctta
    50281 caaaacacaa cgcgtatacg gcttgacttt agatgtcgga atcttcttga atatctcgcc
    50341 tgaccatatc agtccgatcg aacatccgac atttgatgac tatttctatt gcaagcgaca
    50401 attgatcttg aattcaaaaa cagttgtttt aaatcatgaa agtgactatt ttgatttact
    50461 tagggaaaca gccgatctat tccagattcc aacgatcact tatggtcgtt cggaagaaag
    50521 caattatcaa gtgatccgtt cagataaagg tactcacggt tttactttat cttctcatga
    50581 agatcgctta gctatctgcg atactgctta tgatattttg ctggctggag gattcaacca
    50641 agaaaatgca gccagtgcga tcattgccgc agcactaaca ggtgcctcca gtcaagatgc
    50701 acaagacgga ttaaaagaag ctcgtgtacc aggccgaatg gatcaattga tccaatccaa
    50761 tggagcgcat gtctatgtgg actatgcaca taattatcta agcttgaaaa cattgctgaa
    50821 atttgccaaa aatgaacatc cagatggccg tgtaattgtt gtattaggca gcccaggaaa
    50881 caaagcaatc tcccgtcgac atgattttgg aaaagtgcta tcagaaacag ctgacatcgc
    50941 ctttttgacg gcagatgacc cagcatttga agatccgaaa aaaatcgcgg aagaaatcaa
    51001 tgaagcaatt actaatccag atttgatcgt tcattatgaa atggatcgtc ctgaagcgat
    51061 tcgacgcgct ttagcagaaa gcgctccgca agattcagtc gttattgcgg gaaaaggcgt
    51121 ggatccctat caaaaaatca atggtgtaga tgaaccttat gaaggggatt atgcaatcgt
    51181 gaagcggttg attgaagaat aatggtattt atatactagt ggtttcccat ttctaagaaa
    51241 aaaagggact gtgatttttt gtcacagttc cttttttctt agaaatcatt ttaacttttc
    51301 actagctaat tctgctgcct tttctctttc ttcatttaat aatttattat catagaattt
    51361 gataaatggg aaccagataa tgaatgcgat gattgcacaa atgactgcta acacagcagc
    51421 tttccaatca ccaccactac caacaaatgc tccgatcccg actggtgaag gccacggcat
    51481 ctgtgcaagc atcggtttga cgatttccag ccgaatggca aaataagcga gtgtagcaga
    51541 agccatcgga gctaagaaaa acggaaccgc taaataggga ttgtagacga ttggcatccc
    51601 gaaaatgatt ggttcattga tattgaataa tcctggtaca agtgaggctt ttcctaacac
    51661 tttcagctga tcagatttcg cgaggaatgc aataaagatg atcaatccta aagtcgcacc
    51721 tgatccacca acggttacat aagaattgtt gaattctcct gccaacggat aatttgcgcc
    51781 ttgtgcgtta gctgccatat tagctaatac gatcggggtc aagaaagaag tgatgatatt
    51841 cgctccatgg atccctacga tccacaatgc atggatcaag aaataaatca ccatgacacc
    51901 aagccatgta ttcgtcaact gcgtaacaaa cccaaatggg atagcaatca ttttgaagat
    51961 atccgttcct agtgcaacta ataatccatt gatgatcatc accacaaacg caatgacaaa
    52021 tgttgggatc agagcagtga aagaacgaga aactcctggc ggaacaacat ctggcatttt
    52081 tatgacccaa tttctcttga cacacataca atacaattcg accgcaataa tcgacataat
    52141 aatagctgta aagattcctg aagttcctaa acgttcgaca aaagagccca tcctaatacc
    52201 atttactaca gtttctgtct cattgataga agcaatcaag ctgattttac catcagtcat
    52261 gatcaattca gggatacaca taaagaatgc aaaaacagat agtaatgccc ccgtgagcgg
    52321 attaacattt aatttttgtt catctcgttc aattgacgtt aattcataag caaacacaat
    52381 ggcaaagtaa atagataaaa tccccatcgt cattgtattg acgatcatgt acaagtcact
    52441 aactttgaaa aaagttgcat taaaaaatcc ttctaaaaat gggaacggta atggcaaaat
    52501 atttaaaacc aaaaacatcg agcctacaat cgtgaaagga atagaagcca tccccgctgc
    52561 catgacagcc cgaacgattt taagttgcgc aattttcccc ataggtccca tcaggtattt
    52621 ctgcaaaaaa tcaaacatta gttattctcc tttcctaaat ataacgcttt ttcatattgt
    52681 ttaatacgga tatactgttg gtcttggttg agtgaaattt tctttaaacg atactgtata
    52741 aatgcactgg caaaaatacc gcttacaaca agaatgaaaa caaataactg tcctccattg
    52801 ttatttgcca taaaaggata caagaatgta aatcctgagg taaacaacac tggaatcact
    52861 aataaattaa agacactctg gaacaaaaaa taccactttg tccatggaac gttcgtttgg
    52921 tgttttcgat aaagctttac ttgttctcct actgcaggca aaatagctaa aatcagaatc
    52981 atcggtaaac tacttcctaa acttttagct gatagaagca gaatcatcca ttgcatgttc
    53041 atgaaaaaga aaaaggcagt caggtaacgt acgattagat aacgattgaa atacatgttt
    53101 ttcaaactaa gttgcttttt ttctaattcg attttccttt ttactgtatc ctgcacaatg
    53161 atccttcctt tctatttatt tttttgatac aaataattca tttcctgtgc aacttccaat
    53221 aatgtcatcg tcgtcatcag atgatcttgt gcatggacca tgataatttc catttctatt
    53281 tttgtcccgc tggcatattc tttcagaagt tgagtttgtg actgatgcgc atgaagaatc
    53341 tcttcatttg cttgtcgcaa cttctcttct acttcttcaa acatctcttt acgcatcgag
    53401 cgaaatgctt catgtatcag tgtccgtgca tttccgctat ggaaaatgat atcaaaagaa
    53461 gtcacttgta gtgtttcact gtttattttt tcagccatct gttttcctcc ttattcgatc
    53521 agtttgataa atttactgct gaaattctca aaaataggtt cagctaagat ttcctgctgt
    53581 acttttagct ggtcaactaa cctaacgatt gctttagtca cgaccgtaat tccttcattt
    53641 tcgacataag aaggcgaaac taaaaaaaca aaatgaattt cttgatattg atcccactgc
    53701 atcccagaag gaatcaatgc aacggctacc tttgtttcga ttccaactgg aacagcggga
    53761 tgtgggactg ccactgtatc actgaatatg atttgtccca tattttcacg ttgctggatc
    53821 tgctttcgca tttctcttat atatccttct tcttcattta tgctcagctt ttgcagcaaa
    53881 tcatgaagaa tttcttcctt tttcggttcg tacgtataag tcttgaaaaa tttttcagac
    53941 aactgttcgg tgtaaatctg ctttttttgc tgtagagaaa atgctggtat cggtctatct
    54001 gaggaatgat agggtataga ttctccaact acctttcgta ttttacgaac atcatcttca
    54061 ttcaaaaaaa tactgacatg taaaactgga attttgaaaa acattgtcga aagatcaata
    54121 gaagaaataa tcaggtcgat tccttttaaa gttgtttcat tgatctcata atagcctttt
    54181 acacttacca ctgtaatatt tttaccgaat tcactgacta cgcgattctt taatagttgg
    54241 gcactgccgt aacccgttgc acagataatc aatgcatgta gtttatgcgc agctctttct
    54301 ttttccaatg ccgccatgag atgcaaagcc aaataggccc attcatcttc attgatggta
    54361 tagtttttca aagccggcat gttgctgaaa tgccttttta ctgcgtcaaa gactttggga
    54421 ttttctttct ttatctcctc agtcaatggg ttctcaatgc gaatacctcg gctcaatcga
    54481 atcatcatcg gtgacaaatg atcgagtagt ccattgaaaa gctggagatc ctctactaat
    54541 gaaaaatgaa attcctgaga caatcttttc agaactttcg ctaattcctt tgatagttcc
    54601 tgatcatttt gattttcttt gtgattcgac ttagccatga gatgtaatgt caaataagca
    54661 atttcttctt cgggaaacga tacacctgcg attacctcaa tacgttgaac gatccgctgc
    54721 gccacttgat actctactcg cttagaaact tcttgttcga tgcctaattc cttgatttca
    54781 aacccttctc ggagccgttt gatccccaaa gccaagtgta aagtcagatt ctgtatgata
    54841 aaatccgaaa cttttaactt agcttctctt gtttcatcga gaatgataat gactagctct
    54901 tcaaaactga tgtctgggaa aaaacggctt tgccctaaat attctttcaa tgaatttcca
    54961 taatggtttc caaaaaaagt atccatgata aaatgccgtc gatttctttc ttccccttcg
    55021 atccatgtcc cttgaccatg cttagaaacg atttttagtg aatatggaat caatcgctcc
    55081 ttgatttctt gcatgtcctt tgtcaaactg gaacgactga tataaagctc ttctgccaaa
    55141 tcatccataa aaagaatggc atcttccaaa agcaattggt tcaatatata cttttgtcga
    55201 tcttcggact cataaaatcc ttgcggttct ctagcatatc caggtactat ttcttgccga
    55261 ctcaaaaaca agtcaaatgt cagtctttgt aaaatatgca gttggtagcc ataacctggt
    55321 ttagcaatga tcttacctcc gtttttttct actaactctt tgatccgctg caagtaatta
    55381 cggattgtcc gatcagataa taacaattca gaagctaaac gttgactggt gacatactcc
    55441 ttcttgtgat caatcaaata tctcaacagc aatttttcct tctgtttcat tatcatccac
    55501 tcctattcca tcatatgttc tcttcgatca cctctgctaa cttctggatg cctgtaggga
    55561 ttgggacata cgcttggaaa gggatactaa caacaggctt tccaacagat tctcctaatt
    55621 ttttgaattt atccaaaaac atcgtcgttt gcgggctgat cagaaataaa tcaaaatcac
    55681 tattcttaat catattatcg ccttctgtag ctgaaactgc atctacgagt acctcttctc
    55741 ttttttgctt aaagaaatcc gttgtctttg aggccatcat cgaggatgac attcctgccg
    55801 cacaaataat caatgctttt ttcataaatc aatcactcct tttattttta taaaccaagc
    55861 atatcttgta agcgttttct attcaaaata tatatttccg tagcattgcg gaaaaaatgt
    55921 gtatcatatc ttgaataata atttctggca ccgtgatata ctagtgatag aattttttca
    55981 ggaggggatt tagtgagtat cacagtgaat attttgtata caagtacaaa tggacaagcc
    56041 agaaaatttg cagaagaaat ggtcgaaaga aacattgtca aagcgattcg tgcagaagaa
    56101 ggaaacgaga aatatgacta ttactttcca ctagaagatc cagaatctct tttactgatc
    56161 gaccgttgga aagatgaaga agcaatcgaa aagcatcaca aatccgaaat gatggctcaa
    56221 ataaacgaac tccgtaaaaa gtataaatta aaaatgaaag tcgaacgttt cactgattta
    56281 ccgtaaaaag atacacatgg aatgatagca atttatcatc catgtgtatc ttcacttttt
    56341 ccttattttt tattcgatct catctaatga ttcaaaccgt gtttttctct tatttttcgg
    56401 ataagtattt cagtcacccc aatatacatg attcctaaac ataccccaag gatattctca
    56461 aaaatgcgga tcgttactgc tcctggaacc ccgaataaac tggcagtgat tgccaaagca
    56521 ccaaaagaat taaaaactgt tttatatcta taggtagaac aaacacctaa agctagacca
    56581 cctaatatac cgacccagtt aaaaggaata aattggctga taccaataaa taaaacacat
    56641 ccaatcaatg agccaatgat tcggtctact gctcgttctt tgaaaccaat cgacatcaat
    56701 ccatagctag atacaataga agaaaatgca aaccctgccc acatcaatcg ctgaaaaggg
    56761 acatactctc ctgcaacgat caaaagacta atgccaaatg catagatgag catccaaatt
    56821 ttttcctgcg aatacatgcc tttcaaaaaa atctctttaa acaagctttt gtctttgttc
    56881 ttttctcgat gttttctgta aaggagaact gaaaaccaac aaaaaaacaa aaataataag
    56941 ctacttgttt gtgtaaagaa attcttgttc aacgaatctt taggtaacga ataaacaata
    57001 aagagatatg aaaagccgta caaagaagca ttccccattt tgggatcact agcggttgcc
    57061 attaatatgc tgcttagtaa aataaaatga atcaacatgc ccataactga ccatttgatc
    57121 agctggacat acggtgctac taatagtgag aacatgacga ttgctaaacc tatgatcgaa
    57181 tgggaaatct tataaccaaa gtcaacaaaa cgaatactca tcaacataca gaataaaacc
    57241 acagcgtatg gtttatgctt cgattcaaat aatgttgtaa ttataatgat aaaacaaatg
    57301 gcaaacaata cgatgaataa tgatcgtaaa aacaatgaac aaatatacat gcacttttct
    57361 tttttagaag ctgcttctcg tattttttgt tttaaaataa acggatctag ttgtagagac
    57421 tgataaaaat ccacctgttg tcgtcctttc tttttacttt tattttttac agtcatctat
    57481 gacaggttgt aaatactatg gaacatcata tggcgttgtc attttcttgt caactatttt
    57541 tcctattcat gtttttataa aaaaacatat cgttttcttg tatgattaaa tcaccacaaa
    57601 ataaacaact gagagaacga tatgctttat gaatggttct atcaaaaaaa ttctgagatc
    57661 aatagacaaa aatttgatga ttacagaggt ctcttacgaa accttacaga agaaaaaaac
    57721 attgatcgtt gctgcagttc tcttccctgc tccatgtgtc tgtagaaatt gtggttctgc
    57781 tgtggtagat ggaaatagga aattaatggt ggtgaaaaac aagaagaagg aaaccattgt
    57841 ccactttgaa taatataatc atatgccaat ggttatacgc ctaaaaaagc agcgctatac
    57901 ctgtaaaaac tgtcgaagcc attggaacgc tcaaagttat tttatccgtc caaggcactc
    57961 gatttcaaat catgtcagac ataaaatcac ttctttactg actgaaaaag tgtcgttatt
    58021 ttttatttcg aaaagttgtt aggtatcttt gacaaccgtt attcgcacat tgaaagagtt
    58081 gagaagctat ttaccaaagt cttccaaaag aattctgtct tgagtgttga gggttgtgaa
    58141 tttcgttctc acgtttccgt tgaggataaa ctgagtttta tttccgcgga tggcgagaca
    58201 gaaaaattaa tcgagaaaat ttacctacac aaaaaattcc tcgattaaca aactatttcc
    58261 ttagctgcac taatcctaaa gaaatagaat tcttagttac agacatgaac gccacctact
    58321 ttcagctcac caaacatgtt ctaccaaatg cgaaattggt gattgatcga ttacttggtt
    58381 tttccacgcc tttcaaggag gcgtaacctt tattcacgag ttggttgaag ctttccgaga
    58441 caaaagaccc gacttgtttt tctccttatt gacaaagagc cattaaaact agagaaaaaa
    58501 ttacaactga tcgctgatta tttgtagaaa gaaaatcaaa gtattaccca ataaacttga
    58561 gtcattaggc aaaaaacact gcgaaactca agaatgattt tcgcagtgtt tttgtatatt
    58621 ttttattaac tagtattact acaaaggttt atttttcact tctcaacgca gcacaaaatt
    58681 gtctttactt atttactggt tgggttcaac cttctctact ccgatactaa tatttgtttg
    58741 tatacccctt ctaaaatcgg tagtttccat tcaattgatg ggtactagtt gattttaaaa
    58801 actatgctta ttcaattttt tattttagct catatatttc gtttctttct aaattttata
    58861 ctgatgaaaa caagtagcac acccaatatt gacaatataa actggctaat gatggtttct
    58921 ccagtttttg gaagatgctt atttccactg cttgttggat tgtttcctct tatatctgag
    58981 ctatcagcaa cttttctatt ctcttttgtt aaaaagatcg ccacttcttg ttctttttcg
    59041 atcttgaaag ttactggtgt cgcatccaat tcataccccg ttggcgcttg agtttctacc
    59101 agctgatatg ctcctggtgc taagccatct atcgccagtt ttccatctgc tcctgtggtt
    59161 agacctgact gcagaacggt tccattggca tcttgtaact caaaaacagc tccttgcagg
    59221 acttctccgc tttggtcatc gatctttgtc aacacgacac cgcctggtgt aagtcgattt
    59281 tctttcgtca attctaccac cgctgtctga cttctttcga tctcaaactc gattggtgtc
    59341 gcatccaatt cataccccgt tggcgcttgg gtttctacca gctgatacac tcctggtgct
    59401 aagccgtcaa tcgccagttt tccatctgct cctgtggtta gacctgactg cagaacggtt
    59461 ccattggcat cttgtaactc aaaaacagct ccttgcagga cttccccgct ttggtcatcg
    59521 atctttgtca acacgacacc gcctggtgta agtcggtttg ctttcgtcaa ttctaccacc
    59581 gctgtctgac ttctttcgat ctcaaactcg atcggtgtcg catctaattc ataccccgtt
    59641 ggcgcttgag tttctaccag ctgatatg
//
LOCUS       DACCVZ010000008        58243 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.008, whole genome shotgun sequence.
ACCESSION   DACCVZ010000008 DACCVZ010000000
VERSION     DACCVZ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 58243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58243
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.008"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..420
                     /locus_tag="IVW63_000478"
     CDS             <1..420
                     /locus_tag="IVW63_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAP7858781.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(504..1226)
                     /locus_tag="IVW63_000479"
     CDS             complement(504..1226)
                     /locus_tag="IVW63_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAP7858782.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(1216..1953)
                     /locus_tag="IVW63_000480"
     CDS             complement(1216..1953)
                     /locus_tag="IVW63_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7858783.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            complement(1965..2957)
                     /locus_tag="IVW63_000481"
     CDS             complement(1965..2957)
                     /locus_tag="IVW63_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7858784.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            complement(2972..3715)
                     /locus_tag="IVW63_000482"
     CDS             complement(2972..3715)
                     /locus_tag="IVW63_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7858785.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     regulatory      complement(3789..3893)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(3956..5278)
                     /locus_tag="IVW63_000483"
     CDS             complement(3956..5278)
                     /locus_tag="IVW63_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP7858786.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     gene            complement(5265..6230)
                     /locus_tag="IVW63_000484"
     CDS             complement(5265..6230)
                     /locus_tag="IVW63_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7858787.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            complement(6227..7765)
                     /locus_tag="IVW63_000485"
     CDS             complement(6227..7765)
                     /locus_tag="IVW63_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HAP7858788.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            complement(8181..8468)
                     /locus_tag="IVW63_000486"
     CDS             complement(8181..8468)
                     /locus_tag="IVW63_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858789.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            8602..9270
                     /locus_tag="IVW63_000487"
     CDS             8602..9270
                     /locus_tag="IVW63_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP7858790.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(9561..10301)
                     /locus_tag="IVW63_000488"
     CDS             complement(9561..10301)
                     /locus_tag="IVW63_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858791.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(10431..11378)
                     /locus_tag="IVW63_000489"
     CDS             complement(10431..11378)
                     /locus_tag="IVW63_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7858792.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(11507..12271)
                     /locus_tag="IVW63_000490"
     CDS             complement(11507..12271)
                     /locus_tag="IVW63_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP7858793.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(12275..12664)
                     /locus_tag="IVW63_000491"
     CDS             complement(12275..12664)
                     /locus_tag="IVW63_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858794.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            12799..13341
                     /locus_tag="IVW63_000492"
     CDS             12799..13341
                     /locus_tag="IVW63_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HAP7858795.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13489..14121
                     /locus_tag="IVW63_000493"
     CDS             13489..14121
                     /locus_tag="IVW63_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858796.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(14255..14380)
                     /locus_tag="IVW63_000494"
     CDS             complement(14255..14380)
                     /locus_tag="IVW63_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7858797.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(14514..15407)
                     /locus_tag="IVW63_000495"
     CDS             complement(14514..15407)
                     /locus_tag="IVW63_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HAP7858798.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(15589..16515)
                     /locus_tag="IVW63_000496"
     CDS             complement(15589..16515)
                     /locus_tag="IVW63_000496"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HAP7858799.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(16600..17361)
                     /gene="pflA"
                     /locus_tag="IVW63_000497"
     CDS             complement(16600..17361)
                     /gene="pflA"
                     /locus_tag="IVW63_000497"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAP7858800.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(17605..19836)
                     /gene="pflB"
                     /locus_tag="IVW63_000498"
     CDS             complement(17605..19836)
                     /gene="pflB"
                     /locus_tag="IVW63_000498"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAP7858801.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(20113..22563)
                     /gene="parC"
                     /locus_tag="IVW63_000499"
     CDS             complement(20113..22563)
                     /gene="parC"
                     /locus_tag="IVW63_000499"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAP7858802.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(22575..24620)
                     /gene="parE"
                     /locus_tag="IVW63_000500"
     CDS             complement(22575..24620)
                     /gene="parE"
                     /locus_tag="IVW63_000500"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAP7858803.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(24786..25220)
                     /locus_tag="IVW63_000501"
     CDS             complement(24786..25220)
                     /locus_tag="IVW63_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAP7858804.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            25347..25985
                     /gene="plsY"
                     /locus_tag="IVW63_000502"
     CDS             25347..25985
                     /gene="plsY"
                     /locus_tag="IVW63_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAP7858805.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(26117..26992)
                     /locus_tag="IVW63_000503"
     CDS             complement(26117..26992)
                     /locus_tag="IVW63_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAP7858806.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(27074..27865)
                     /gene="codY"
                     /locus_tag="IVW63_000504"
     CDS             complement(27074..27865)
                     /gene="codY"
                     /locus_tag="IVW63_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAP7858807.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(27883..29283)
                     /gene="hslU"
                     /locus_tag="IVW63_000505"
     CDS             complement(27883..29283)
                     /gene="hslU"
                     /locus_tag="IVW63_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAP7858808.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(29297..29845)
                     /gene="hslV"
                     /locus_tag="IVW63_000506"
     CDS             complement(29297..29845)
                     /gene="hslV"
                     /locus_tag="IVW63_000506"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAP7858809.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(29882..30787)
                     /gene="xerC"
                     /locus_tag="IVW63_000507"
     CDS             complement(29882..30787)
                     /gene="xerC"
                     /locus_tag="IVW63_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAP7858810.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(30985..32361)
                     /gene="trmFO"
                     /locus_tag="IVW63_000508"
     CDS             complement(30985..32361)
                     /gene="trmFO"
                     /locus_tag="IVW63_000508"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAP7858811.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(32330..34408)
                     /gene="topA"
                     /locus_tag="IVW63_000509"
     CDS             complement(32330..34408)
                     /gene="topA"
                     /locus_tag="IVW63_000509"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAP7858812.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(34530..35387)
                     /gene="dprA"
                     /locus_tag="IVW63_000510"
     CDS             complement(34530..35387)
                     /gene="dprA"
                     /locus_tag="IVW63_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAP7858813.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(35443..36210)
                     /locus_tag="IVW63_000511"
     CDS             complement(35443..36210)
                     /locus_tag="IVW63_000511"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAP7858814.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(36203..37063)
                     /gene="ylqF"
                     /locus_tag="IVW63_000512"
     CDS             complement(36203..37063)
                     /gene="ylqF"
                     /locus_tag="IVW63_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAP7858815.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            37323..37721
                     /locus_tag="IVW63_000513"
     CDS             37323..37721
                     /locus_tag="IVW63_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP7858816.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            37958..38500
                     /locus_tag="IVW63_000514"
     CDS             37958..38500
                     /locus_tag="IVW63_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAP7858817.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(38583..39134)
                     /gene="lepB"
                     /locus_tag="IVW63_000515"
     CDS             complement(38583..39134)
                     /gene="lepB"
                     /locus_tag="IVW63_000515"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP7858818.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(39286..39513)
                     /locus_tag="IVW63_000516"
     CDS             complement(39286..39513)
                     /locus_tag="IVW63_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAP7858819.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(39510..40028)
                     /gene="msrA"
                     /locus_tag="IVW63_000517"
     CDS             complement(39510..40028)
                     /gene="msrA"
                     /locus_tag="IVW63_000517"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP7858820.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(40048..40761)
                     /locus_tag="IVW63_000518"
     CDS             complement(40048..40761)
                     /locus_tag="IVW63_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAP7858821.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(40764..41660)
                     /locus_tag="IVW63_000519"
     CDS             complement(40764..41660)
                     /locus_tag="IVW63_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP7858822.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(41818..42660)
                     /locus_tag="IVW63_000520"
     CDS             complement(41818..42660)
                     /locus_tag="IVW63_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP7858823.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            42792..43445
                     /locus_tag="IVW63_000521"
     CDS             42792..43445
                     /locus_tag="IVW63_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAP7858824.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(43508..44035)
                     /locus_tag="IVW63_000522"
     CDS             complement(43508..44035)
                     /locus_tag="IVW63_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP7858825.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(44055..45002)
                     /locus_tag="IVW63_000523"
     CDS             complement(44055..45002)
                     /locus_tag="IVW63_000523"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAP7858826.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(45014..46900)
                     /locus_tag="IVW63_000524"
     CDS             complement(45014..46900)
                     /locus_tag="IVW63_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP7858827.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(47060..49138)
                     /locus_tag="IVW63_000525"
     CDS             complement(47060..49138)
                     /locus_tag="IVW63_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAP7858828.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(49151..49426)
                     /locus_tag="IVW63_000526"
     CDS             complement(49151..49426)
                     /locus_tag="IVW63_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858829.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(49788..50243)
                     /locus_tag="IVW63_000527"
     CDS             complement(49788..50243)
                     /locus_tag="IVW63_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858830.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(50397..51605)
                     /locus_tag="IVW63_000528"
     CDS             complement(50397..51605)
                     /locus_tag="IVW63_000528"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAP7858831.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(51717..52049)
                     /locus_tag="IVW63_000529"
     CDS             complement(51717..52049)
                     /locus_tag="IVW63_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAP7858832.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            52197..53072
                     /locus_tag="IVW63_000530"
     CDS             52197..53072
                     /locus_tag="IVW63_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP7858833.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(53154..53735)
                     /locus_tag="IVW63_000531"
     CDS             complement(53154..53735)
                     /locus_tag="IVW63_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAP7858834.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(53741..55000)
                     /locus_tag="IVW63_000532"
     CDS             complement(53741..55000)
                     /locus_tag="IVW63_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAP7858835.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(55002..56048)
                     /locus_tag="IVW63_000533"
     CDS             complement(55002..56048)
                     /locus_tag="IVW63_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858836.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(56283..56558)
                     /locus_tag="IVW63_000534"
     CDS             complement(56283..56558)
                     /locus_tag="IVW63_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAP7858837.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(56801..58111)
                     /locus_tag="IVW63_000535"
     CDS             complement(56801..58111)
                     /locus_tag="IVW63_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAP7858838.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
BASE COUNT        16026 a        12204 c         9953 g        20060 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacaac ctgttgtaca agaaacggtt
      121 caaacggaaa aacaagcagc gcctgttgct gaaacacaac ctgctcctgc tgtaacagaa
      181 actgctgcta ctccagcaag cacaagctct gcaaaagaat ggatcgcaca aaaagaatca
      241 agcggttctt acacagcaac gaacggacgt tacatcggac gttaccaatt agattcttct
      301 tacttaaatg gtgactactc tgctgcaaac caagaaagag tagcagaaca atatgttact
      361 tcacgttatg gttcttggga agcggcgaaa gcattctggg aagcaaacgg ttggtactaa
      421 gattcattta ttaatcaaac agtttacttt tatacaaaga aagccaaaaa gaggtgcgac
      481 actagttgtg tcacatctct tttttattta cctaatctaa tgaaacgttc caagttttga
      541 taagtatttt ttttaacttc ttcaactgat agctctttga tctcagcgat tgtctttaac
      601 tgttcttcaa gcagtgagac ataatctttt tctgaaaaaa tcccccctaa agcccactct
      661 gctgcatgta gtccatccgt ttcaataagt aagtggtcga ttgggactgc tttagctagt
      721 tgccagactg ctggattctt tttcaaatca agaccaatgc tgaaataaca gcctaaatca
      781 atatagtctt gttgatagtc caaagaagaa taccaatgga tcaaatagtg attagggtaa
      841 gcttggatat aatttaagat ctctttttcg catccttttg tgtgcagtac aacaggtttc
      901 tcatttatgg ctgcaaaagc aagctgtcgc tcaaatactt ttttttgtgt agtcatcggt
      961 acattcgtcc aaatattatc taaccctatt tcaccgatga tccttgcttt tttcaaaaaa
     1021 ggctcaactt gttcaaacgt atagctatct gctttccaag gatggatacc gtaacttaag
     1081 gcttgagtct tacttgctgc aagctgtctg ttttccttcc attcttctgg cgaatcacaa
     1141 ttgatgatcg tcaaaatcgt gtgttcctgc tgaaggagtg ctaaactctg actcccatct
     1201 aaatgacaat gagcatcact taacatctaa ttcacctgcc aataactgat aaatcgtttg
     1261 cttcaactct gattgctgca gtagccattc acgtgaccgt cgtttttcag gcacttgaat
     1321 ctcagcaatc acatgtgccg gacgggcgga aagcacaaga atcctgtctg ataaataaat
     1381 tgcttcttcg atatcatgcg tcacaagtaa agtagtccgc tttgcttttt taggcagctt
     1441 caacatccag tcttgcatct gccctctggt catagcatct aacgctccaa atggttcatc
     1501 aagaagcaag taagaagaag gattcatgat tgttcgtaac aaggccgttc gctgcttcat
     1561 cccgccagat aattgttccg gcaaaaaatg ttcatagccg tttaacccaa agatatccag
     1621 ataatccctt acttgttctt cattgattgt tagatgattg attttttgat ataacgtaac
     1681 gttttgatag acgctcagcc aaggaagtaa catatcttct tgcggcatat aactaaatgc
     1741 tgtatggaga ccagttactt tttgatcgtc tactttgatc gttccagaag tcataggctg
     1801 gactcctgtt aaagttttca gcaatgttga cttaccggct ccgcttggcg cgacaatcga
     1861 tgtaaaggta tctttaggga tagtgaaatg gatgtcttct aatattttca ggttttcaat
     1921 gactacattc aagtggctga tttggattga catatctatc actcctattt tataaactga
     1981 ttagtgaata gttcttgcga aggtacatct tgcttgatca atccgttttc ctgcataaaa
     2041 gctgtataat tgcgccaaac tttttcttcc atcaatcccc aattctcagg atcatccgta
     2101 taattttttg acaagaatgc ttgtgattct tctaaaaacg tccgatcatt ttcttttgca
     2161 tatttttgca acagtttagc actgtcattt ggatccttaa tagcttcctg atagcctttt
     2221 ttcgtggcat ccataaaaga ctgtaccaat tctggatcac ttttgatcag ttgatcattc
     2281 gtaataatta ccggagtata gtaatctaac cgttcatcta attctttcaa tgggatatag
     2341 tttagttcaa tacccgcttc ttttgctttg atcatatccc aaccttcaaa gtaccattgg
     2401 atatctgagg attttcctaa gctttctggc ccttctccat tgcttcctac cattgtcagt
     2461 tttgaaaagt ccccgccgtc tttttccatc acagctttta agacagcttc ttcacttgga
     2521 ctttgccaac ctgcatatgt ttttccttca aaatcttttg gtgaatggat gttactgtct
     2581 gatagggtgg cgaatccaga agtattatgt ttgatcactg tagcaattgc tttgactggt
     2641 atattctgtc catctgcgtg agcataagtg acatcttctt gataacttac accaaattgt
     2701 gctttgtccg cacctactag accaatactt gtcgaattat ctcctggttc gatgatttgg
     2761 acatttaaac cagcctcttt ataatagcct ttttcttttg ctaggtagat gccagtatga
     2821 ttagtattcg gtacataatc caaaacaagt gtcacttttt tcaaatcctt tatttcttgt
     2881 ttgctacttg tttcttttgc agtgccacaa gcggataaaa gcaacagtag cggtaataaa
     2941 agccataatt ttttcatttg atccccttct cttaaaaaat ataaagcata cgataatacc
     3001 cttttttcaa taatgaacaa gcgccattca gcaataaact caatagaatg acacaaatga
     3061 tcgcagcaaa aactttatcg atctggtagc tgttttttac gcgtatcatg taatacccta
     3121 agcctgcttg agcgcttagc cattctccaa cgactgctcc gctgacacaa taagtagcag
     3181 ccacttttaa accggaaaag aagccggata aacccgctgg tattttatat attcgataaa
     3241 tcttccctgt atctgccccc atcgttttca aaaagatgat ttgctctttt gatactttcc
     3301 tcaatgtatc cgaaaaagaa actacgatcg gaaaatagct tatcaagaca acaaggatca
     3361 cttttggaag cataccgaaa ccaaaccata gggtaagtaa tggccctaac accatgattg
     3421 gcaacatttg tgaaatcact agtaacggat aaaaagacat ttctaaaaac ttccaataat
     3481 ccattgccaa ggcagtaata aaagaaagaa cgctagctat taccaaacca agcactgctt
     3541 catttaatgt cgtgacagaa tgggaaagta atacttgtgc atctgccgct aatgcagaaa
     3601 atacagcagc aggtccgggt aaaataaagg caggtatttt ccaaactatg acaacaatct
     3661 gccaaataat taaaatgaat gccatactga ctgctggata aagatttttc ttcattttgt
     3721 tacctccttt cttctaatat gaataacaaa aaacgcttga aatgggcacg acatagtaac
     3781 ccgcttcaag cgtctgctat gtttctccct tcaccagtat taactgacag gttcaatggg
     3841 tctaagttca caacttactc tcatgtcgtc tacgacatcc ccagaaacag gtattcattt
     3901 tttaaagtgt agcacaagaa ggaaaaagca acaagcgctt tagttatcat gctgattatt
     3961 tcaataaata ggagagatca cttgccaatg tcggataccc catgatatag ctatccaact
     4021 cttttttagt caatttttga ttgatgacga gtgtcaaatc atcgatcaat tcgtctgctt
     4081 gctcgctaat cactgcagca ccaatcaaat aattttgctg gtcaaaggtc aattcagcct
     4141 tagcaactgg ttcattgaca cgatgatagg tgaaccaact ggtaagatcc atctctacca
     4201 cttgatctga cgaagaggcg tgactttttg taactcctac ttcagcaagt ttaggactgg
     4261 cgtagacgat cgtaggtata atcggatatt tgataggttc gcttgttgca tccgttatcc
     4321 gcttagctac ataatttcct tcaaaagtgg cgactggtgt caattttggg gttttccttg
     4381 aaacaatatc tccacacgca aaaatttttg gattgctcgt ttgcagataa tcattgactg
     4441 caattccgtg tttatcaaag acgatattcg cttgctcaag tgctaaagat tctgtattcg
     4501 gctgtctccc agtcgcacaa aaaatcatat ctgctactaa ttccgtctct tttccgacta
     4561 aacgatagcg agtaccttct gaaatgatct tttgggtttc aacaccaaaa gcaaactgaa
     4621 tgccagatgc ttccatttga tggacggctt cctctaccaa agacgcctca aattctttta
     4681 atggccgttg attatgatgg acaatggtta ctttgctccc tgcagcattg gcaatcgtag
     4741 ctagctcaaa agcaatataa ccaccaccga taaaaatgat ttctttaggc agtacaggca
     4801 atgataaaaa gtctgcacta gttttcaagt attcctttcc ctccactggt aagatcgtag
     4861 gtctttgccc ggttgccaaa actaagtaat ccgcatggaa gacttcttcg ttgacttcaa
     4921 tagatgaatc atccaaaaaa cgagcggttc ctgaaagatg atcgatttca gcttctgcta
     4981 attgtttttt tcggctttct gggactggat ccgtaaatgt tcgtttgaat ttttgaagtt
     5041 cttcccagtt ggcagttggg atctcgttaa aaccttttcc actcaattgt tttacccgat
     5101 tacgtgcctc tactgcactt aacaagactt ttttaggatc acatccacgg ttaggacaag
     5161 tcccgcccca tagatcttct tcgaccacta gtactgtttt acctgcttct ttcaatccat
     5221 aagcagcact taagccgctc acacctgaac cgatgatgat tgcatcatat gttttcattt
     5281 ccttcctcct ctcgacttaa aaaagcaaag atttctttac ttgtcagcga cccaatactt
     5341 ctttgctttt ctactatcac aatgcttgga tacaccgaaa gaagcgaata tacttctttc
     5401 ataggcgtat caaagcaaac ttgttgacga gcattttctg gtatttcatt taagaaatat
     5461 ccattgacga ctaaatcttc tactcgccac tctttcgtct gtttcggttc atcaaagaaa
     5521 tgccgaacgt agtcgttttt aggattcatc aataactgct ctggtgtgtc acattggata
     5581 atttctccat ccttcataaa tgcaatacga tcacctagct tgattgcttc ttccatattg
     5641 tgcgtaacga aaacgatggt cgtgcccaat tcttcgtgta aggacaaaac caattcttgt
     5701 aatgagtttc ttgaaatcgg atctaatgcg ctaaatggct cgtccatcaa aatcacatct
     5761 gggcttgcag caatagctcg gatgatcccg atccgttgct gttctcctcc agacaactct
     5821 ctaggcatac gatctcgata aatatcagga gataagccaa ctttttgaag aagttcatct
     5881 acacggtctg ctcttttctg cttttcccaa cctaacattt cagggatgac ttcaatattt
     5941 tgcttgactg tcatggtcgg gaacaaagcg atttgctgca gcacatatcc catattccac
     6001 cgcattttct gcagattata ttcatttaac gattttcctt tgaagtagat gtctcctgct
     6061 gatggtttag ataatccatt gatcattttc aaagtagttg tttttccact accggaagga
     6121 ccaaccaaaa caaagatttc tccttttttg attgccagat ttaggtcatc gatgacatac
     6181 tttccatcat actttttttg cacatgtttg aactcgatta atttagtcac tgatcttcct
     6241 cctttactaa tccttcattt ttcaggaaga ttcgtgctac ttctgtcggc tttttctttt
     6301 cgacattgac ttggtaattc atatcaatca tttgatcctc tgttattttt ccgcttaatt
     6361 tattcagtgc tttaacgatt tcaggatgtt ctttagcaaa atcttttttc atcagcggtg
     6421 cgccttgata agctgggaat aaccctcgat catcttctag agtcactaga tcgtactcct
     6481 tgagctggct atctgtggaa taggcatcca caatattgac atctccatta ttgattgctt
     6541 ggtaacgcaa acttggctcc atgctttgta cacttgaaaa attcaagcca tatgcttctt
     6601 ggattccttt atatccatct gaacgatcaa taaattccag tgtgaatccc gctttgatct
     6661 gatcagagat agctgccaaa tcggaaatct ttttaagttg atgttcgttc gcaaaagatc
     6721 tcttgactgc caaggcatac gtattttggt aagccattgg ttttaataat gtcatatcga
     6781 attgcttatt caataattct tctgcttcgt catatgtttt ttcttttgtc aaatcagcac
     6841 ttttcattgc ttcaggtacc ttcaccaagc tttctaggac agtacctgtg aactcaggat
     6901 agatatcgat ttgaccttga tccagtgcat tgaacaaaaa actcgtcttg ccaaaattcg
     6961 gttttaattc aacttctgtt tttgtgttgt cttcaatcaa ttctttatac atttggatca
     7021 ggatttcagg ttccgctcct aattttccag caatcgtgat ggtttcattt ttaaacaagg
     7081 cagactgata taaagaaacg ccgccaaata aacacaccac tgctgctaaa gtaatgatgg
     7141 aatatcgagg tttcttatgc tgcaaccagc gaatcagtcc gctgaatata attgcaagca
     7201 aggcagaact gatcgcacca atcaatgtca aaacaggtgt atttcggtca atacctaaca
     7261 aaataaatgt ccctaatcca cctgctccga tcaatgctgc caaagtagcc gtaccgatga
     7321 ttaaaactaa ggcagttcgg atacctgaga taatgacagg taatgcgatg ggaagctcta
     7381 ctttcagcaa gcgtctcatt ctggacatac caaatgctac cgctgcttct tcaatagacg
     7441 ggtcaatttc agctagacca atatacgtgt tttggaaaat cggaagcaaa gcgtaaataa
     7501 caagtgcaat caatgctgga acagttccga tccctacaaa tgggataagt aaacctaata
     7561 aggcaagtga aggaatcgtt tggagcacac ccgtgatctg caataagact tctgccattt
     7621 ttttatgatt ggctgcccaa atcgctaaag gaatagcaat cagtgctgca atcagcaaag
     7681 aaatgagaga aatggacaga tgttgaaatg cagcttccag caactcgcct tttctttcac
     7741 ttaatgtttg tataaaatta ttcatgcgac cttcctttct gttattcttt aagtataaac
     7801 atttctttcc tttttcccaa ctaacttgtc ttgccttaac cttacagcac gaacaaaaaa
     7861 aagaaaaaaa tacctctaaa tatgctgaca aaaaaagaat ccaagcaaca aagtcggatc
     7921 aactttttgg ttctcgtttt ttcactacga ataccataaa aatctatacg aaattgtcac
     7981 ttggaatcag ctatatcttt tttacacaca caacttttat tttaataaaa agaaacagcc
     8041 aataaagtag aaatctcgtg ggggagaaca cctttattgg cctgttcaac gaatattata
     8101 ctgtatcatg acactttttt gccaaaaatg taaaaaatgg ttgttttgac atcataaacg
     8161 tcttgttttc ttatttttac ttatatcacc actttatttt ctatctcttt cactccataa
     8221 agaggaatga gttcttcttt tgactgataa taaacagctt tctcacggtt cttcatcaaa
     8281 aaaagaaaga tgtctttcat agcaagtggt gctttgccgt gttcaaataa aaagataaat
     8341 tgatttgctt tatttatctg gaccattgtc acaggcacca gtttttgttc ttgagccaaa
     8401 aaaactcctt gatactctgt ttttttgggt gattttgtaa gaattgtcaa taagtctgct
     8461 gctcgcattt ttccactcct tatttgataa ataaaaagaa acagccaaaa ataatttttt
     8521 ttcattttcc tcttgaagta agagtataag tcagtataat aaagaagttg ctgaaaattt
     8581 tcaaaagaaa agaggctaga aatgaaaaaa ttaaatttat ttacagaatt gtgcggaatc
     8641 attttaggcg caggaatcta cggattagct gtgacaggaa tcaatattcc atctaagctg
     8701 gcagatggtg gggttactgg tattgctttg cttttgcata atctttttgg attcgctcct
     8761 tctgtcactt cactgctttt taatttacct ttattgctta tctcattgtt tctttttgga
     8821 aaacacgctt ttctccggac gatcgtcgga acatttgcgc tagttttctt tttacattta
     8881 tgggagagcc ttcatataca ttttgctgta gatagtctac tgatcaatag tttgatgaca
     8941 ggtattcttt ctggcattgg ttgcggtctc gtctttcgat tcggcggaag cacaggcgga
     9001 acagatatca tttatcaagc cattgaaaaa tattttcata ttaagattgg caaaagtctt
     9061 ttcttgatta cttttggtat tttagttgtc tccttgcttt atttggatct cacacatttt
     9121 ctgtatacat tacttagctg ttctattcta tcttatacat tgaataaagt gaagtatctg
     9181 gaaattggat ctgttttgcc ccaattggaa gcaaaacaga ctacagaaac atttgaacca
     9241 cttgatcctc ttgaacagtt agagcactga ttcttatttt tcactacttt atttaattta
     9301 cagaaatatc attatgtaaa ctaaaatgat attattcagt aaaatcttct ttataaaaaa
     9361 ataaactatt tttgcaaacg atctgcgaaa atagtttgtt tttttatttt gccattattt
     9421 tcttacttat tgggagaaaa aattcgctta aactcaaaaa aatttgagga tacgatataa
     9481 actttcggat agagtataaa ataaggaaac gccgcagcgt ttcctttcca actgtagccg
     9541 aatataaatt tgtatatcac ttatttaaaa tagctatttt ctcccaaaga gtttccttga
     9601 tcatcgatca atccttgtaa tgagcgttct aagataccat ggcttttttt cgattttttt
     9661 tcttctgact gctttgtttc ctctaacgtt tttgttcgat tgaatgttcg tacagacggc
     9721 tcaccatttc ttttttcttg atacggcgtc ggttctgtat cgaacaacag ataagagtca
     9781 tccgtttttt tcatcgattc gattaaatga tcctcagaaa ttttgctttc tctagggtct
     9841 gggataatcg atgcgggtac atatttagga acaaaataag aacgctcccg caccttcgtg
     9901 tcaacagatg cgtttcgtgt agtatgcttg gactctgtcc ttgtttcact ttgtctgaca
     9961 gaacgagagg aatcaccaaa aagttttttt cgtcctgtcg atgtgatttc tgattggtaa
    10021 tggccggtat aatccggtaa ttttccttta tgcttttcca aattttcctt acgcggagct
    10081 gacttcaatc catttgttgc acgacgcttg cgacggattt tctcggtgtt cgtgttcgtg
    10141 aaatgaaatt ctttcatctg ttcaaacggg gactgattct gttcagtcaa aagatcttct
    10201 tgtccgtcaa ataatactcg cttcttgtcg ttggttaatt ttacgcctaa ctcatcatcg
    10261 tacgcaggaa aacggaaatg ttttcgtctg atttctttca ttcaaaccat ccttctcaaa
    10321 aatggaactt ttctcaataa tagcacagat tcattgtttt cagtagcaat gcgctgatta
    10381 ttttaagaaa atagcgatga atttcataaa tatatatata gtaataagac ttaattcgtt
    10441 gtctctctga taactagttc aggaaaaaaa cgacgataac cttgactcgc ccctttttct
    10501 tctatttttt ttaacaacat ttctccacat acttcaccca tacgtataat atcttgcttg
    10561 atcgttgtca atttaggtga actgatttgg tctaaaaata ccccatcaaa tccaatcaca
    10621 ccaaattctt cgggcaagtg tcctccagca tttataatcc ctcttactgc tcctagtgct
    10681 agccgatctg aactacatac aaaacaagtt ttatctgtaa aatctgccca gttttctgtc
    10741 atatatcttt ctacttctgt cgaatgattt ggaaaccgca agattttact aggaagatca
    10801 acttccttca tcacagataa ataaccagtt tcccttgaaa tttcaaaagg ctcgtccact
    10861 tcgataccga tataaataat cgtttgataa tctctttcta aggcatattg cgttgctttt
    10921 gctgtaccat attcattatc gctgtctaca taatcatatc cttcagaatt ttccccaaac
    10981 aagacaactg gtttttccaa acggtcgatc caatcgaagt ctttttttct gacacctgtg
    11041 atgatgtatc catcacaaga accgacgtcg aaggcatcat ttgtaactaa ttggagagaa
    11101 taatgcgctt taccgatccg tttagcgatt cccatcagca aattcatgta atagggctca
    11161 gttgtgtcga tttcttccag tataaataat ttgatgatct gcgaccgatt cgtgacaagt
    11221 gcttttgcag caatatttgg acggtaatcc agttcagcca ttgctgagaa aactaactct
    11281 ttcaattcgt cagtcacctg ttccggatga ttgatgactc gagagaccgt catttttgaa
    11341 acattggcac gttttgcaac atctgctaaa gtgggcatgc tctcttcctt tctaacatgt
    11401 tgtcattctt actatcaatt ataccaaatt ttcctaacag agtttattat agcccaaaat
    11461 aaaaaacgga aaatcctcta tcgtcatgag tgattttccg tttcaattat ttatactttt
    11521 ttatcaaatt ttttgctaaa aaagtggaag cttcttccat tagtggtatt tgtaccatat
    11581 gtcgctgtgt ttttgaggaa cgaaaaacaa tttcttttcc gtaagactta tgccgatttt
    11641 tttctacaaa tcgttccgtt tgtatataag ggattttttc gtcagcttgt ccatgccaaa
    11701 agaacagagg acgtccagct aacttttccg gctgcaatga caaatcatag ctcttaaccc
    11761 atgaaatcaa atcaaaatag tcttttggta cgacataatt atattccgat gcgcgcctta
    11821 cgatttcttt tccatattcc aaaggtgcag gggaacccat caaacacacg cccgctacta
    11881 tatgaggatg tttagccaac aaggcgcatg ttgtcattcc ccccatcgaa accccgccaa
    11941 ctgcaagctg atcatgtaga agacctcttt tttctaaatg cttgataagt gtgtcaaatt
    12001 caaacagatt tccgtagata ctatcccaaa atgtatagga tggaatagaa gaaaccggct
    12061 gtttgcgctc cccatgattc atcgcatctg gcaggatcac acgaatgccc tgctgcgcaa
    12121 tttttcttcc ttgcgtcaaa actaactcct tacttgtctg ccatccgtga taatagatga
    12181 caacgggaat acgttcctct cttaattctt tcagaacaac ttctaacact ggaatatgat
    12241 ggacagaacg tttcaatata attggattca attgttactc acctattttc attaaatttc
    12301 ctgatcgcca tagcaaccat gctccaacag ttgtctggaa caggttcagt gtaccaaata
    12361 atataaatgc aggactgaat ggctcgggaa ataagcacag agaacaaagt cccaccactc
    12421 ctaatgctag cgaaaggagt ggataaatag aaaaattcaa aaaactggca acgctaccga
    12481 aaatattacc aataaacagt atcaaaaaga aaaaaacgct taaaattaaa ccatctgtca
    12541 gcgacatctg aaaaacaatg ttctctacct caattggctg ttgaatcgaa tagacaccta
    12601 agtatatact gagaaggaga cttagcacgt ggctggcaca aaacacacga ttgaccgttt
    12661 tcattttaat cacctaacct atctttataa ttctattata atcattttat catttttttg
    12721 tatgtataaa gtttcaattt ttcttcactt acgatttttt ttgatattgt tgttatataa
    12781 atgaaaggag ttttacaaat gattgatcca aaaatgttgg ggatgatctt cctcattaat
    12841 tttgcttata tcactctgaa cacgttacgt ttcatgttga caatgaaagg ctatcgactg
    12901 attgctccac ttgtcagtat ggtcgagatc acgatttata tcgtcggctt atcccttgtt
    12961 ttagatcgtt tagataatcc actgaattta tttgtctatg cgttaggtta cgcagtaggt
    13021 atcagtgtcg gaattttgat tgaagacaaa ttggcattag gatacatcat ggtcacaacg
    13081 attttgccag caaatagcgc agaagataaa agtttgccgg gtatactgag agaacacggt
    13141 tatggtgtga cacagacttc tgcaatgggg ctggaaggtg agcggctagt tctcgaaata
    13201 ctttctccta gaaaaagcga acgtgaactg tatcgcctga tcaaagaaat cgaagagcgt
    13261 gcttttatca tttcttatga gccaaaatat atttcaggtg gtttctggac taaaaaagtg
    13321 agaaaacgac aaggaaaata actcacaaac ttaaaaactg tctaatatct aaattaaatt
    13381 ttaaatgtta gacagttttt atttattatt ttgattaaaa aacatcgaca tatactcatc
    13441 aatttgttat tatactttat atacttatca atttaatttg gagatattat ggaaattcaa
    13501 cgtagaacca ctaatttttt acatttaggc tctttttttg caactttgac gatcttattt
    13561 tttctatgtt attcatacct taagacctca catgcgcctt ctagtgcatt aggctggttg
    13621 cttttggatc attctgatat cacagaagcc gaagaaaatc cgtttttttt gattttgtct
    13681 tctctttgcg gcttactgtt ttctgtttat ttcggtgcct atttttttca tcgacatcct
    13741 ggtacgttaa acgaagcttc aagcgtattg attgcattta aaacgttttc ttttttagca
    13801 attctttttt attcgtttaa tcacaatacg cttttcttct ttatcatgaa tggtttagtc
    13861 gtgattttat ccatttttac ttattttatt ttttcactca tttttagcca attgaaatgt
    13921 ccgctcttct ttcgattagt tcctgtcacc tgttttattt acagcttgtt ttcctttttt
    13981 gtccttgctt taatgccact gaccaaccct tcgacgatcc aagtcgcagg aaatctgttg
    14041 gatatgctct tcatcgtcag tctaggtgta tttatgtggc aaagaaaaaa caaacaaaat
    14101 aaaaagcatt ttgaagcctg actattacga cttcataaat gcttttttag ttttaaacac
    14161 ttcaatctaa aagaataacc caagattgga taaattatta atgactcgcc attcgtttct
    14221 tagtgattct ggattatcaa atggacttcc taatctaatc agctagttct tcccataaaa
    14281 tgccatactt gactgaatca taatattgat tatttaaaaa tctaactttt cttatcacta
    14341 cttcctttgt cattccacat ttctcaccat ttttttgcat tcctttgttt ccagaccatg
    14401 tagtgaatct aataggtggt agataggcaa aatactcaaa taattctttt aaccataaag
    14461 gaagagaaag gctcctcctg caagagtcag tataattttt gcttactgct ctcttaggtt
    14521 ttactcacta aaactgttcc atattctttg atataagaaa atgcatgcgg tataaatttc
    14581 ttgctcagct cagaaaagat ttgtcgttta agaaaggcca tttcctccat tgtcaatgaa
    14641 ggatccaatg ttggtaattc aatctcaaaa ttgttttttt cgacaatagg taattctaat
    14701 gtgaatgatt cttcttcctt tatagtattc gtcacaagta gagactgatg gaaaatacta
    14761 ggccggcgat ttttatattt attcttacgt atcctgtcaa cgataacttc tatttgatca
    14821 aaaaagtacg attcatttac gtctccaata agttcggcta attctttgaa tgccttcgtt
    14881 acaggaagct gattcttctg tacaaaaaag taattagcca aagtaagcgg gaagtgttct
    14941 atagaggaaa gtgtgataaa acggtacttc tcatttcctg cagttgtcct cagcaattct
    15001 gtctctcggc tgtttcttac tccataaaaa tacgcttctt tccgttcatc ttcgaaacaa
    15061 tacgcccaaa taacttctcc catcgctaat ttttgttcat caacagagag tctcttcaat
    15121 tgttcagcta tggtttcagc agccgaagtg gcttgttgca agtaatcttt aggatcaaat
    15181 attggaaagt tcaaatgata tcttcgttct tccctcttga ttaatcctgc atcgatcaat
    15241 aaatcaagaa aatgggaaaa tttattttgc gaaaattctt ttttcaattc tcttagaatc
    15301 gtttcttgtt ctcgatgttc atatagataa tcggtcaatg aagaaaaaag cggatcatcg
    15361 gtcagttttt gataaaagtt ttccttattt tttgaataat agttcatata tgttctcttt
    15421 tctatccgtt ttattttact taaaaggctt ttacgtaaaa aggaggaaga acaagagtca
    15481 taattgactg ttattctcct ccatttcttc ggcctttagt atgttctatg tttcttttta
    15541 tatcaatcgc ttatccattc attttgaatg cttcatacta ccatttgatt agctaaatac
    15601 agccgtcaat tgaggtacga cttgtttttt acgtgaaacg acacctttaa gcaaagcacg
    15661 gttgttggtc aaagttgttt ggaaagcttc ttctactttt tcttttcctt taccagcaac
    15721 aagtaattct gaatcactgt ctaagatgtt tgtgacaact aatacgaaca gatcgtagcc
    15781 atttgctttc atttcatctt ccattgctgc ttctagctct gcttgtcgat ccatcacttc
    15841 attaaggtcc actgtattga cttgagcgat acgaacgttg gaactgccca ttgggaaact
    15901 ttttgcatcc aaatcaagaa gaaccgcagc tgatttatca cttagatttg ttcctgcttt
    15961 caacatttca agtccataag tgtttagatc gacttcagcg attgctgcaa gttcttttgc
    16021 agctgcttca tcttcaggcg tacatgttgg tgatttgaac aacaatgtat ctgaaatgat
    16081 agctgagagc atgattcctg cgatttcttt aggaattgtt acttggtttt ctttatatag
    16141 ttttaaaata atcgtacttg tacatccaac tggttctgca cgatagtaca atggattagc
    16201 tgtttcaaag tttgcaatac gatggtggtc tactacagct aaaatattta cttcgctgat
    16261 atctgaaata ctttgttgga attcattatg atccacaagc atgacatctg cattttctgc
    16321 tttagctgac tctactactc gtggtgcaga tagctgaaag tggtctaatg cgtattgtgt
    16381 ttcttcatta ggtgtaccta gagcaactgc ttctgtttct ttacctaatt cattttgcaa
    16441 gtgtgaaaac gcaatggctg ccccgattgc atctgtatct ggattttggt gaccaaaaac
    16501 taaaattttt gacatgtcat tcgctccttt gtgatttctc ctatttaata atagcaaaaa
    16561 aacggaaaga agcaatactt atcttctttc cgatgcgacc tatcgcgtta aatattttgt
    16621 atactcttct gtatgaagca atcgtttagc attttcgaca cgttcttttg taggtggttc
    16681 gatcccttct aatggatatt tcaaaccaag tgtttcccac ttgtattttc ccatcgtatg
    16741 ataaggaaga atctctactc tgtctacatt tgacaaggtt tgaataaagt tgtctagtcg
    16801 gatcaaatat tcatcataat cacttcgctc aggaactagt acatggcgaa tccaaaccgg
    16861 tttgttgatt tttgacaaat attgagccat ttctaaaata ttttcattgt cccaatgcgt
    16921 tagtttttta tgctcttcat tatcgatgtg tttgatgtca aataacagta aatctgtata
    16981 cttcatcaat tcttgaaaac gtgaaaagaa aggttcttca tacgtaaaag gttttccgca
    17041 tgtatccaat gtagtatgca tcttccgctc ttttgctttt ttaaatagtt cgatcaaaaa
    17101 atcgatctgc aatagaggtt ctccaccact aacagtaata ccacctttat ctccccagta
    17161 aggtctgaag cgttctgctt tatctaaaag ttcatctgct gtgtattctt tccctccgcc
    17221 aatattccaa gtatctggat tgtgacaaaa ttggcaacgc atgcggcatc cttgcataaa
    17281 cacgacaaag cgcagtccag gtccgtctac tgaaccgaaa gtttcgatag aatgaacata
    17341 gccgattgtt ttttcttcca tttaagttca catcttttct ttgatttcat tttaagtaca
    17401 agttagctgt cgaagcgaag ctttctgaac aaaatttttc gcaattgccg cttcgttatg
    17461 tgtaaaattt acagggacgg aacatacaag tcctgcccct gtaaatcgtt tctttcaaat
    17521 aagcatactg attattcgat tttgatgcga tggctattca acgtcctttc gacgctaagt
    17581 cgaaaaactt ttttcacgaa ctttttacat tctgtcgtgt gaagttctca tcaagacatc
    17641 taattgttgt tctcttgtca agtcacggaa tttaactgca taaccagata cccggatcgt
    17701 caagttcgga tatttcattg gattttccat tgcatcacgc aataaatcat tactgaatac
    17761 attgacattc aaatgataag ctccttttga gaagtatcca tctaagacat tacgcaagtt
    17821 ttcgattctt gtatcttgtt cttttccaag acctgaagga ttgattgttt gggtatttga
    17881 aattccatcc aatgcacagc cgtaattcat tttagctgtt gagttcaggc tagctaataa
    17941 cccactttgt tccgcattgt aacttggatt tgctcctggc gcaagtggtt ttccagcttc
    18001 acggccatca ggagtatttc ctgtattttt accgtaaaca acatttgaag taatcgtcaa
    18061 taatgaagtt gttggttttg agttgcggta agttttatga cgtttgattt gtcccatgaa
    18121 gtattccaag atccatgaaa ctaattcatc tgcacggtca tcatcatttc cgtatttagg
    18181 gaagtcgcca tccacttcaa aatcaactgc tattcctttt tcattacgga ttgcttttac
    18241 ttttgcatat ttgatcgctg acaagctgtc tgccgcatga gagatcccag caatacctgt
    18301 agcaaatgtg cgttgcaagt cagaatccat caaagccagc tgagctgctt cataagaata
    18361 tttatcatgc atataatgaa tgatgttcaa cgtattgaca tatagttctg ctaaccaatc
    18421 catcatattc atgaagttat gtttcacttc ttcaaagtct agtatttctg atgtgattgg
    18481 acgatattct ggtccaactt gggcgccagt cacttcatcg actccgccat tgatggcata
    18541 taatagtgtt ttagccaagt tagcacgagc gccaaagaat tgcatgtctt ttccgacaac
    18601 tgttcctgat acacagcaag caatcgcaca atcatcagaa ccccattgtt cacgaagctg
    18661 attatcattt tcgaattgaa tcgaagaact ttcgatagcg attctgctag catatgttct
    18721 gaatccttct ggaaggtgtt cagaatacaa aacagtcaag tttggttctg gtgaaggtcc
    18781 catatttgtt aatgtatgaa gcagacggaa atcattcttt gtaactaatg aacgaccatc
    18841 taatcccata cctgcaatgg ataaagtagc ccagataggg aatcctgaga ataattggtt
    18901 atattcaggt gtacgcgcga atttgaccat acgtaatttc attactaagt ggtcgatcaa
    18961 ttcttgtgct tctttttctg tgattactcc attatccaaa tcacgttgga tatagatatc
    19021 aaggaatgct gagatacgtc cgattgacat cgcagcacca ttttgtgatt tgattgctgc
    19081 taaatatccg aagtatagcc attggacagc ttcttttgca tttgcagctg gtttagaaat
    19141 atcatagcca tatttcgcag ccatttcttt catttgcgct aatgcacgat attgttcagt
    19201 gatttcttca cgtaaacgaa tcacttcttc actcattgta tgataaccag tcatatcatg
    19261 atcttttttc ttttgttcca tcaaatagtc gattccatac aatgccacac gacgatagtc
    19321 accgatgata cgtccgcgac cgtaagcgtc tggaagccct gtaatgattt tgtttttacg
    19381 agcagcacgc atttcagcag tataagcgtc aaatacacct tgattatgtg ttttgcgcca
    19441 gtcagtgaaa atatgtgtca attcatcgtt tggtgtatag ccattgcttt ttagcgcatt
    19501 gttagccata ttgattccgc cgaacggcat gaatgcttgt ttcaaaggtt tgtctgtctg
    19561 tagaccgacg attttttcca aatctttatc caaatagcct gcatcgtgtg aagtaatagt
    19621 tgatacgatt tctgtgtcca tatcatagac accgttacgc tcgaattgga tatcatttaa
    19681 cttttgcaat tcatcccata atttttctgt tgcttctgtt gggccttcca aaaagctgtc
    19741 atcaccgcga tattcagtgt agttattttg aataaagtct ctagtgtcta cgccttcttt
    19801 ccatttggta cctttaaatc cattccattg ctccattgta tggacctcct aaatttctgt
    19861 tttatgtaac agtttttacg tgattagtat aacacagcac cctatctttg caagggtttt
    19921 cttgtttttt atttaacaat ttttatgttt tatttacata tatttaaatc aacgttgaca
    19981 taccaacatt taagcattgt gaacactttc atcttttttt gcaaacgtat aaggatttat
    20041 taaaaatgaa tgaaaaagag acgccacctg tattaataca gatggcgtct cttcattaaa
    20101 atactacaac agttacgact cgatgaaaat ctcaggagca tcgataactt cgatgacttc
    20161 tccacctttt ttctcatcca tcgcaaatga tccattcgat gttcgatcac ctatagggaa
    20221 atcagttggg tcaatcgtta actgctgccc tttttgattc atcaaggtta tttcttttga
    20281 tcttccttcc gacatataga taatacggtg cggatttttt ttcagctcac gcatgaccgt
    20341 cactccccgc ttcgcacgtg aagtttggct gatttcttga gcaagcatgc gtttaacagc
    20401 tcctcgctga gtaacgatta cgatcggcgt atcaccttct gctaacacaa gcagcccgtt
    20461 gataatccta tctccatctt tcaaattcat agacttcact ccagctgcct ttgctccaac
    20521 aacgggaaca tctgttaaag gatagcgcaa acccattcct tgatgcgtta ctaagaaaac
    20581 atctaagcct ggctgatctt ctttcagata cacagcaatc agttcatctt cttccgcctt
    20641 tagcttcata cagctgagcg gacggctctt ataggtgcgc catggttcga actctgtcat
    20701 tcgtgtttgc ttgatcaatc cattcttgct gatgaataca aatgttttct ctgcttgaat
    20761 tttttgatat gggaaaacag ctaaaatcga ttcgtctaca gacagattgg agattgtttg
    20821 agaaatgtgc tcaccagcat ctttccattt caaatcgggt agttcatgga cagggcggta
    20881 gatcacattt gctttatttg tgatcagaag aacatggtcc aatgtactca attcacctga
    20941 gtatagcaag tagtcgcctt ctcgcatccc gatttcttct ggtttggaag cactataaga
    21001 acgaaggctt gttcgcttca catagccttc tcgcgtcaca ctgacaatta cgtcttcttg
    21061 tgccactaag acttgcgtat caattttgat ttcttcgatt tcgtcttcga ttgtcgttag
    21121 acgagcggaa gaataatttt ttttcacttc tcgcaattct tttttcataa cagagaaaag
    21181 ctctttgtca tttgaaagga ttttattcaa ctctgtgatt tgcgcaatca agctttcgga
    21241 ttccttttga agctctgtga tatccgtgtt cgtcaaacgg tataattgca atgtgacaat
    21301 tgcttctgct tgttcttctg taaattgaaa gacgtcgact aaattctttt tggcgtcttt
    21361 tttgtcttta ctttcacgaa tcgttgcgat tacttcatcc agaatcgata aagctttcat
    21421 caatccttct acgatatgct gtcttttttg agctttggct aaatcgaatt gactacgttt
    21481 tgttatgact tgctttcgat gctcgatata acttcttaaa atgtctttca gtccaacttg
    21541 atgcggagtc atatggtcga tagcgaccat attgaaattg taattgatct gtagctcagt
    21601 gtttttgaac aaataattca aaattccttg agcattggcg tcttttttca attcgacgac
    21661 aatttgcaga cctgttctat cactttcatc tcgtacttca gctattccat cgattttctt
    21721 attcaaacgg atctcatcca tttttttcac caaggtcgct ttatttactt catatgggat
    21781 ttctgtgatc acgatttgct gtttattacc cttcattgcc tctatctttg ttttcgaacg
    21841 aagaataact tttcctcgtc ctgtttcata agcttttttg atttcatctt ttccttgcaa
    21901 gatccctcct gttggaaagt caggtccagg aatatattcc atcaattttt caaggctcgc
    21961 ttgtggatga tcgatcatat agattgtgcc atcgatcact tcagctaagt tatgagtcgg
    22021 gatttctgtt gcatatccag cagatatacc tgtcgatcca ttgacgagaa ggtttgggta
    22081 tcgagctgga aggactgttg gttctttttc tgtatcatca aaattccaca cgagatcgac
    22141 tgtttctttc tcgatatctg ctagcatctc tccacttaac ttggataatc tggcttcagt
    22201 ataacgcatc gcagcaggtg gatcaccgtc catactcccg ttattcccgt gcatttcgat
    22261 cagtacttcc cgcaacttcc agtcttggct catgcggacc atcgcttcat aaatactgat
    22321 gtcaccatga ggatgataat tccccatgat atttccgaca gattttgctg atttacggaa
    22381 tcctttgtca tacgtattgc catctttgtt catggcaaat aatatccggc gttgcactgg
    22441 cttcaatcca tcacggatat caggcagtgc acgttcttgg ataatatatt tggaataacg
    22501 tccgaagcgg tcacccatca cttcttctaa agttaattct tgtacttctt gtcgattttc
    22561 catcaggtga cctcctattc tacttcaaat aactgattgt tttcattttt atctgctcgt
    22621 tcttcatcta ataaatcatt agaaactgaa ggagagattt cagtatcctc ttttttatct
    22681 aagatactgc catcttcttc gagcgtaaat tgcacgtgat tttcgatcca ttttcttcga
    22741 ggttctactt tgtcacccat cagtgtggtt actcgacgtt cagcttgcgc agcatcatcg
    22801 atacggacgc ggatcaacgt acgggaagtc ggatccatcg ttgtttccca caattgttcc
    22861 gcattcatct ctccaagtcc tttatatcgc tgcagcatat atcctttgcc gactttttta
    22921 atcattgctg ccaattcgtc atctgtccac gcatattcaa tgacttgctt ctttccttgt
    22981 cctttggata ctttatataa aggcggtaac gcgatatata ctttcccagc ttcaatcagc
    23041 ggtttcatat aacgataaaa gaaagtaagc agtaatactt gaatatgggc gccgtctgta
    23101 tccgcatcgg tcatgatgat tactttgtcg taattacagt cttcgataga aaactcagga
    23161 ccgactcctg caccaatcgt atagatcatc gtattgattt cttcattttt caagatatct
    23221 tgcattttag ctttttcggt attgatgact tttcctcgta aaggtagaat tgcttggaac
    23281 tttctgtctc ttccttgttt agcagatccg ccagcagaat ccccttcgac taaatacaat
    23341 tcatttttct tagggtttcg ggattgtgcg ggtgtcaatt ttcctgaaag aagagattcg
    23401 ccttttttac gcttcttccc atttcggctt tcttctctgg ctttacgtgc tgcttctctc
    23461 gcttctctgg ctttgattgc tttacggacc aacatctggc tcatttcgct attttcctgc
    23521 aaataaaagc ccatttgttc actgatgacg ttatctacta cggtacgagc aactggcgta
    23581 ccaagttttt cttttgtttg cccttcaaat tgcagaagat tttcaggtac acggatagaa
    23641 agtacagcag ctaacccttc tctgaaatca ctaccttcca gattcttgtc ccgttctttc
    23701 agcaaaccaa cttttctcgc atattcatta taagatttcg tcatcgccgc tttcatacca
    23761 gcttcatggg ttcccccatc ttttgtccga acgttattga caaaagataa aacattttct
    23821 gaataaccgt cattgtattg ataagcgacc tctacttcga taccttcttt ttctcctgaa
    23881 aaataaacaa ctggtgtcaa tgtatctttt tcttcattca gataatcaac aaattctttg
    23941 attccttctt cgtaatgaaa aatttccttg actggttctt ctccacgaag atcagaaaga
    24001 gagattttaa cgccttttag aagaaaggca gattctctta accgttcggc taaaatttca
    24061 tatgaaaatt tcgttgtact gaatattgta tcatctggta aaaaatggac agtcgtcccg
    24121 tttgcttttt ttgtttttcc tatctttttc aaagtaccgt caggtttacc gccgttttta
    24181 aatttctgct gatactctac gccatctcta acgatcgtta caattagcca tttcgataag
    24241 gcatttacca cactggctcc tacaccgtgc agtccaccag aagttttgta ccctccttga
    24301 ccaaactttc cgccagcatg cagcacagta aaaatcactt caactgttgg tattccggaa
    24361 gcatgcattc ctacaggcat cccacgtccg ctatctgcaa cagttatact attgtcttca
    24421 tggatggtca catcaatctc actgccataa cctgataatg cttcgtcaac tgcattatcg
    24481 acgatttcat agactaaatg atgcaagcct cggctgtcag tggatccaat gtacatccct
    24541 ggtctttttc taactgcctc taatccttcc aatacttgga tggacgagtc attgtattcg
    24601 ttgtttactt tttttgccaa ggcaaacgct ccttcaataa tactttgcgg caaaaccgca
    24661 ccacgattat catactagaa aaggtcgtga aaaaaaagag ggtagacgag aaatcaattt
    24721 taattatctc ctaaccgctt tttcgacatt cccctctatc gatcatctct tctttgtggt
    24781 catttttatt tttggttttc tttcaactta ccaagttcaa tcttaataca acgatccatt
    24841 acgatatctg tacgtcctgc ttttcttagc atctcagctg cttctttgtt ttcaatccct
    24901 aattgtgccc agaacacttt agcatcagtt ttcaaaaaat cacctgctat ttcaggtaaa
    24961 aattcactcc gtctaaatac atctacgata tcgattggat catcgatttc tgtcaaattc
    25021 gcatagactt tctcgcctag aatttcttca ccagccaata atggatttac tggtatgatt
    25081 ttatatccat tgtcttgcaa tacctgtgca accatgtaac ttgttcgttc tggtttattg
    25141 ctcaagccta cgacggcaat attttttgct tcttccaaat agttgaaaat cgtttcttgt
    25201 gttggatttt ttacagacat ttctgccacc ccttgctttt ctttttattc catctattat
    25261 acttgtatct ttcatttttt caattgttcc tgttacctat tcatgctaaa ataaaggata
    25321 gttttcaact tgaaagaggg taaaaaatga aattgatctt attacttatt ttagcatatc
    25381 ttttaggttc tattccttcc ggtgtctgga ttggcaaatt gtttttcaaa aaagatatcc
    25441 gacaacacgg gagcggtaat actggaacga ccaatacatt tcgtgtatta ggcaaaacag
    25501 ccgggattgt tgtcctgctt atggatattt taaaaggtac attggctact tgtttgccga
    25561 tgatcttcca cctttctggg attaaccctc tttggtttgg ggtatgcgcc attcttggcc
    25621 atacatttcc gatttttgct gggttcaaag gaggaaaagc tgttgcgaca agtgcaggaa
    25681 tgcttttagg atttaatcct gtattttttg tttattcttg tatcatcttt atcgttagtt
    25741 tattttgtac aagtatggtg agtttgagca gtatgatcag tgcagtattg atcactttat
    25801 ctacgatcgt ccttccttat gtagctcctg tgattttggc taagcccaat tggttactga
    25861 cgatcattgc ctttttagtt tcttccttta tcttttatcg gcataaagac aatatcaagc
    25921 gtatcagaaa ccatactgaa agtcgaatcc cgtttggttt gaatagcagc aagaaaaaat
    25981 cctgatactt tttcattcca aagagataaa acgggagtgt gacaaatcga tgtcacactc
    26041 ccttattact tacaggatag cttttttaca caccttggta aacggtgttc cctgctaact
    26101 tctcggtcac aacctcttac ttcactgtga tggaatattt tgtcttgaag atttcatggg
    26161 cacctagttg attgatccct actttttcca tcaagtttcc actactgttc accgtgtcag
    26221 cgattccgca ccacggttcg atacaaacga aaggcgcttc ttttggataa ggagaccaga
    26281 tccctacata aggcatatct ttatagctta aagttacgct atgggaagat ttttcacttc
    26341 gaatggcgta cgcatttaga ccccttgttt caaaaaccaa ggcatcttgc tcaaaaagtt
    26401 cacgattcaa agccagattc gtatttgtct gacctaacgt cttttgatcc atatcgatga
    26461 atgggccttt caatggtagg cgtaatcttg atttcaatgg agaaaatgcc agatagaaat
    26521 cttcaaatga caatccttct tcaagaggta cattgaaagc aggatgtcca ccgatagaaa
    26581 agaacatttc tttttcaccg gtatttgcca cttgataatg aaccgtgatg ccgtctcctc
    26641 ctaattcata gctgatcact aattcaaaat caaatggata cttttctaat gtctccggcg
    26701 tactccttaa gatgaaacta gccatttctt gtccatgttc aatgacttca aaatccatat
    26761 cccgagcaaa tccgtgttgc cccatttgat atgttttccc ttgataaaca tactgatcat
    26821 cttttaaacg tccaacaaaa gggaataaaa ccggtgcatg tctgccccaa tacgctggat
    26881 caccttgcca gatatactct aaaccatgtt cttttgattt cagactgatc aattccgcac
    26941 cgtgttcagc gatttcggcg atcagctggt cattttgaat aataacagtc attgccattc
    27001 ctccaacttc gacttacttt ttaaaatggg aaggctggaa caaacatttc tatctgcccc
    27061 agtcccctta cttctaataa ctgtgttttg ctaactcgtc tttaaaacgg gaattcaata
    27121 cttttaaata agttcccttc atgcctaacg aacgagattc aatgattcca gctgattcca
    27181 attttcgtaa agcattgacg atcacagaac gagtgatgcc gatactatcg gcaatattag
    27241 aagcagtcag acgaccttca tctccatcca atgcttcaaa gatagcttgt acagccttca
    27301 attcgctata agataatgtg ttgattgcca tttggacagc cgttgcactc cgtacatctg
    27361 cttcgatgct tcgagacttc tgataaagga tctgcatacc gacaaccgta gctccatatt
    27421 ctgctaagac tagatcgtca tctgcaaacg attgttccat acgagataag ataatcgtac
    27481 ccaaacgttc gccagctcca aagatcggaa cgacagtcgt cagaccaaat ggatatttct
    27541 ctcttgactc taccggaaat gcagtaatat cactagtaat tgggatatta gcttcagttt
    27601 tcatcaactg tgccactgta tcagtataag attcaggaaa ttgtttctca acaaacattg
    27661 ttttgattcg ttcattgttc acatcgtgac gttcattata acctagtaat actccgtcac
    27721 ttcctatgat ataggtgttg ctgtcaagaa taccacctag tgtgacagcc attttatcgt
    27781 aaggcaaatc tgcttgcatg tcaaaagtat tcttttgctg caaaagtgtg tttatcttgc
    27841 gggttttcgt tagcaagtct gtcattgtcg tcctccgatt ttttataaaa tatagcgact
    27901 taaatcttca tttgccgcaa ttgagccaag tttgtcatcc acatatgctt ctgtgatcgt
    27961 tatttctccc atttgcatat ctggtgcttc aaataataga tcttctagta gtttttccaa
    28021 aatggtatgc agtctgcgtg cgccgatatt atctgtgtca cggttgacat cgaaagcgat
    28081 ttgagcgatc cgttcaattg cttcttttgt aaacgtaact gacacatttt ctgtaccgat
    28141 caacgcgacg tattgtttta ctaaagcatt atttggttcg gtcagaatct tcacaaaatc
    28201 ttcagctgtc aaatcatcta attctacccg tatcgggaag cgtccttgaa gttctggaat
    28261 tagatcactt ggtttagaca aatggaaagc tcctgaagca atgaatagga cgtgatctgt
    28321 ttggatgatc ccgtattttg tgtttacttg tgaaccttcg acaattggca atatgtctct
    28381 ttggacgcct tctctggata cttctccaga ttgctgtgat ttagaagtga tcttatcgat
    28441 ttcatcgata aaaataattc cactttcttc cgctaatttg attgcctcac tatggatatc
    28501 agcatccttg actaattttg ctgattcttc cttgatcaat aactctaaag cttctttgac
    28561 tgttaccgtc cgttccactt ttttcttcgg tgtcaaagca cctagagttt catttaggtc
    28621 gatccccatt tgctccaatc cattgttcat cattggtgca ggtttctttt ggtcttcaac
    28681 ttcaatggtt acttcacgac tatccagtaa acccttttgt agttgttcca agactgtacg
    28741 gcgattgatt cgaatatctt ctgtcacttc ttcttgcggt tcagcggtat tttgctgact
    28801 agcattaaaa agattcatca tttgttcaaa ttgattagtg gattgtttct gttctttttt
    28861 gataccaggt accaagattt ttaccaaacg tttttctgca ttttttttag cacttgtgta
    28921 tacacggctg tactgctctt tttctacgat ttggatcgca ttttctacta aatcccgaac
    28981 cattgattct acatctcttc cgacataacc gacttcagta aattttgttg cttcgacttt
    29041 gacaaatggt gcattgacga tttttgccaa acgtcgtgcg atttctgttt taccgacccc
    29101 tgtaggtccg atcatcagca tattttttgg tgtaatatct tgttgcattt tttcatctaa
    29161 ctgcaaacgg cgatagcggt tacgcaaagc aacggcaaca gatttttttg ctgcgtgctg
    29221 tcctacgata tattcatcta attcacttac gatttgtctt ggtgtttgtt ttaattcata
    29281 catatctact cacctcttac agttcttcta cgataatatt atgattagta aagatacaga
    29341 tatctgcggc aatatttaac gcattttctg caatttcttt cgcactcatg tcgttttgag
    29401 catagttttt cattgctcgg gctgcagcca acgcaaaatt ccctcctgat ccgatagcta
    29461 agataccatc atctggtgtg ataacttctc ctgtacctga aacaagaagc atttctttat
    29521 cattcattac gatcagcatc gcttcaagtt tttgcataga ttgctgtgtc cgccattctt
    29581 gagctaattc gacagctgcg cgttgtagat tcccgttata ttcgtttagt ttgccttcaa
    29641 atttttcttc taaagtaaac gcatctgcaa cacttccggc gaaacctaca acaacttctc
    29701 cattgtagat acgtcgtact ttctttgcag tgcctttcat gacaacagat tcacccattg
    29761 ttacttggcc atctccagcc atagcaaatt tcccgtcttt ttcgacggca cagatagtgg
    29821 ttgaatgaaa tggtgattcg accatgtttg tttcctccta aatttgttct tttccttatt
    29881 tttacgctct tggatggaaa gaacgatagt ttttttgtaa actttctttt gttacatggg
    29941 catagatctg ggtagtcgat aaattggcat gtcctagcaa ttcttggact gtccgcaaat
    30001 ctgccccatt atttaataaa tgagtagcaa atgtatggcg cagcatgtga ggatggatat
    30061 cactatccaa actgcttttt ttgatcattt gattcaagac atattcaatt ccagtaggcg
    30121 tgattggttt tccatgatga ttcacaaaaa cgatatcatg ctcttcgtga tattttgtca
    30181 tcaatacctg gcggccttcc ctgaaatatt cttgcagagc atcttgagca aaagaaccta
    30241 gaggagcata tctctctttg ttccctttac catggatcaa catgacctct gaatcaaaat
    30301 caatgtctga taccgacaaa ctgctacact cacttaaacg gatgcctgac ccgtaaagga
    30361 cttccagtaa agcgcggttc ctcaaatcca aaggactatc tcctgctacg ctgtcaaaaa
    30421 gtgcttgcat ttcattttca taaaaaaaac gtggcagtct caaatttttc tttttgagat
    30481 gaacgtaaga aaatggattt tcttttatca cttcttcttt gagaagatac tgataaaacg
    30541 aacgtaggct ggctatcttg cgactgatag aatttctgct atagctagga cgatgatcag
    30601 ctaatgcact caaatagaca cgaaccgtaa aatattccgc cttcagcaga tcagcgtctc
    30661 cagattcctc caaaaaatgt ttgaaatgga gaatgtcttc ttcatatgct tctttcgttt
    30721 tttctgaata tcctctttcg acaatcaaat aacgcaaaaa tttttgttcc cacgtggctt
    30781 ctgtcatttt ctcaccttcc ttttgtccca gagaataatt tagcacagcg tttataaaaa
    30841 gacaaataaa ttgtcagaat ttaaccaata tttctaagtt tgttcacaat tggcgcaatt
    30901 cctcacattt tgtttgagaa attcttaaga aaaacgcaag aaaaagagcg agactatccg
    30961 tctcaccctc ttcatggagt ttccttactc atttgggatt gcagtttttt ctaattctgt
    31021 ttttattgcc tcattagctt ttaaagctcg ttgtgcaatt gcttcatatc ttgctttttt
    31081 gtctcgaatg cgctctggca gttcaggaaa cagaccatag ttggcattca tcggttggaa
    31141 atgttttcct tccgcatgag taatgtagta agccatactt ccaatagctg tttcttgtgg
    31201 aaactcgact ggttccattt cttttgctaa gcgtgcggcg ttgattccag caagtagtcc
    31261 gctcgctgca ctttcaacat agccttctac accagtcatc tgacctgcaa agaacagatc
    31321 ttcgcgtttc gttgattggt aagtcggttt cagcaattct ggcgaattca taaagctgtt
    31381 tcggtgcatc acaccatagc gaacgaattc agcattttct aacccaggaa tcatccggaa
    31441 aacacgtttt tgctcgcccc atttcaagtg agtctgaaag cccacgatgt tgtataaaga
    31501 agctgcagca ttgtcttgac gcagctggat aacagcataa ggacgtttgc cagttttagg
    31561 atcttccaat ccaactggtt tcataggtcc gaaaagcatc gttttgaatc ctcgctgtgc
    31621 cattacttca attggcatac atccttcaaa atatttttct ttctcaaaag atttaagttc
    31681 tgccacttcg gcattgatta gtgcctcatg gaaagctttg aattcctctt ctgtcatcgg
    31741 acagttcaag taagctgctt ctcctttgtc atagcgggac ttcaaatata ctttatccat
    31801 atcgatcgta gctttgtcta cgattggtgc agctgcatca tagaaataaa aaccatctga
    31861 accattgaat gctttgatgc tttctgctaa tggatgagaa gtcaaaggtc ctgttgctac
    31921 tacggtgatt ccttccggta tttcagtaat ttcttcgttt atcactgtta ctaatggatg
    31981 ctctttgact tttcgggtaa ttgtttcaga aaaagaatcg cggtcaacag ctaaggcacc
    32041 accagctggc actgctgttt catctgccga agtgattact accgaattca atcggcgcat
    32101 ttcttctttc aataacccta ctgcattagc caaactgttt cctcttaatg aattggaaca
    32161 tactagttca gcaaaattac ttgtgtgatg cgcctcagtc gatttgactg gacgcatttc
    32221 atataaacgg acagggactc ctgcttgtgc gatctgccaa gcagcttcac ttccggcaag
    32281 ccctgctcca acaacattta ccattttcaa tgaaagaacc tcttttctat tatttttgga
    32341 tgtcttcttc gtaatctcca tttacacaga ctacttgttt accgcctttg actttcttct
    32401 cgaccagata tccgtcacat tttggacaat ttctgcccac tggtttatcc caagaagtga
    32461 attcacattc tgggaaacgg gaacaaccat agaatagtct gtttttctta gattttcgtt
    32521 caatgacttg tccttcatga catactgggc aagtcacacc gatttctttt acgattggtt
    32581 tcgtattccg acaatcagga aaattactgc aagcataaaa cttcccatat ttccctaatt
    32641 ttatcaccat cggatgtcca cagacatcac aatcgaatcc tgctggttca tctttgattt
    32701 gaattttttc gattttttct tccgcattcg tcagttcttt ttcaaacggt ttatagaaac
    32761 gatcaaccac tttgacccac gcttccgtgc cttcttcaat tttatccaaa tctccttcca
    32821 tttctgctgt gaaatggata tcgacgattt gagggaagaa ttcacagatt aatgaattga
    32881 caatttctcc tagttcagtc ggctcaaatc ttttttgtgt caattttaca tagtagcgtc
    32941 tttggatcgt atcaagtgtt ggtgcataag tggaaggtcg ccctaccccg ttttcttcta
    33001 gtgcacgaat caacgtagcc tcactaaaac gtgctggtgg ttgagtaaaa tgttgttttg
    33061 gttcaatatc aacagattgg actacatcgc cttcttcaag ttctggaaga atattttctt
    33121 tctcttcttt gccgtcatct ctaccttcca catacacttg catgaatcct ttgaatttga
    33181 tttttgaacc gttcgcaatg aagatgacac cattttgttc taatgtcact ttcattgtat
    33241 ctaaaatagc tggtgtcatc tgactagcca caaaacgtga ccagatcaat gtataaagtt
    33301 tcaattgatc tttatctaaa tattgtttga gttcatctgg tgtacgaagc acactcgttg
    33361 gacgcacagc ttcatgggca tcttgtgcgc cttgagcatt tttgatcttt cggtgatcat
    33421 gtctagaaaa ttcttttcca tacgtatctt caataaatgc tgcggcctct gcttttgctg
    33481 tatcggcaat ccgggtagaa tcagtacgca tgtatgtaat caagccgact gttccttgtt
    33541 tacccaaagt gattccttca tataattgct gtgctaccat catggttttt cttgttcgaa
    33601 agtttaactt acgggcagct tcttgttgca ggctacttgt agtgaaagga ttcgcagggt
    33661 ttcttttgcg ctctttcttt tctacttttt taacttcgaa gtctgttcca tcaattctag
    33721 cagtgacttc ttttacactt tgtgcatctg gtaatttctt tttcttaccg tcgattcccc
    33781 agaaatttgc tttgaatttc ttgcgagctt ttttaaaatt accgtcgatg ctccaatatt
    33841 cttctggaac aaattctcgg atctcttttt cacggtcaat aataattttt aaagcgacag
    33901 attggacacg tcctgcactt aaccctttct tgaccttacg ccagagaata ggactgatcg
    33961 aataaccaac gattctgtct aaggtacgac gagcttgctg tgcatctact aaatctacat
    34021 cgatcgttct tggttcctta aaagctgctt tgactgcgtc ttttgtgatt tcattgaaga
    34081 ccacccgatt tttttctttc agatccaacc caagtaggta cgctaaatgc caagcaatcg
    34141 cttctccttc tctatccggg tcacttgcca agtaaacttt ttgagctttt tttgctgcgg
    34201 ctttcaggct tttgatgaca tcgccttttc cgcgtataga aatataatgg ggttcataat
    34261 tgttttcaaa atcgataccc attttacttt tcggtaaatc tcttatatgg ccaacactgg
    34321 ccattacttt atagtttcgt ccaagatatt tctcaattgt cttggctttt gcaggtgatt
    34381 ctacaatcac taaatattta tacgccatta ctgaatggac tcctttccat tgtcgtgttc
    34441 ctactattaa aagaggattc atacaaatcg tagctaatca tatccattca gaaaacgttt
    34501 gtcaagaaaa gcaaatgaaa agtatggtgt tattctttaa attctgccaa gatatcttca
    34561 cccgaaaccg tgcaaactgc accgtcttgg atcaaatgat gacatccggt agaatgttct
    34621 gttaaaatat ttcctggaac agaaaaaact gttcttccaa gatccaatgc ttgctgtgct
    34681 gttatcagag agccgctttt tttcttggct tcaaagacac atgttccttt agacaaagct
    34741 gcgataatcc gatttctcat tggaaaacaa tgctttttcg ggccggattg aggaggatat
    34801 tcactcaaaa gaagatgatc atttgcaatc acctcttgca agtcacgatt ttcagcagga
    34861 tagacttgct ctatccctgt tccaatgact gcgattgtcc gtccaccatg agagattgct
    34921 gcttggtgac cgtatgtatc tatccctttc gcgcagccac tgacgatcac atatccagct
    34981 tctatcactg gttttagtaa ataataaact gtttttttgg ctaaagcaga agtgtgtctt
    35041 ccaccaacaa cgcttaacat gttacaagaa agtaaagata gatcaccatt ataaaacagt
    35101 acaattggcg gataggtcaa gtgaagcagc tgagggggat atttgggatc aaagcaagtg
    35161 ataaacgact gtttcgattg gattttgccc cagttagcgt gaatttcctg ccaacttttg
    35221 cgaaacagct cccggtgttt ggttatttta cctatcttaa tgatgtcttc aaatccgatt
    35281 tctttataag gatactgcat catccagtta gcaagtgccc attttccttg actactgatt
    35341 ccttttgtat aagcaagttt caataaattt tcttctattt gatacatcat aaaaccgcct
    35401 ttcgtctctc tttctaataa gatacgtaaa agcggctgtt ttttattgta aatatttttt
    35461 tacaggtgca aaacttttac gatggattgg cgtaattcct tgtcgttcaa gtccttctaa
    35521 gtgttccttt gttccataac ctgcattatg cgagaaacca tatccaggat aaagcacgtc
    35581 atattctttc atcaattggt ctcgatatac tttagcaatg atacttgcag cagcaatcga
    35641 cacagatcgt gcatcccctt tgattatttt ttcctgctga ataggcaaat ccaaggtcat
    35701 cgcatcgatc aacaaatagc ttggtacaat ggacaatttt tctactgctt ggatcatcgc
    35761 taatttactt gcttcataaa tattcacatc atcgattgtc tgctgatcaa cgatcccgat
    35821 cccgattgcc agggcttttt cttgaacttg ttgataaaga agttctcgct ttttctctga
    35881 taattgtttg gagtcattca gccctaatat gatctcattt ttcggcaaga taactgcagc
    35941 tgccacgaca ggtccagcta atggtcctct tcctacttca tcaatgccgg caatccattg
    36001 gtgaccttgt gcgtaccctt gcttttcaaa gcaaaacatt tcttcatatt tttccttaat
    36061 taatgcttcc tttttcaatc gtcgttcaaa agaagccagt gcttgctgca cgcctttgcg
    36121 tggatcattt cttaatgatt ctagtgtagg atcatctatt ctctgtatgc ttttcaatcg
    36181 ttctttgata ctttggatgg attcagtcat cacttttttg ctccatttct tcgcaacgat
    36241 ccagtgtgta tcgtccaagt tttccttgac gaatatcatg cacgactaat tcgctgccac
    36301 gatcatagtc ttctttatac ccacgttttg ctgtaatatc catcagtaat tccggtgcca
    36361 atttttcttc ttgctcgatt gataaaccat aacgatcgct gattcttcct gaataatatc
    36421 gggcaaaaaa gtctaatccg taaatcgcta aatcatctaa atggacaagc tggtctttga
    36481 tcgcgcctgt cagcgctagt tttttgccga tttcttcatc ttcaaatttg ggccataaaa
    36541 tccctggtgt gtctaacaat tccaactcat tacctaaacg aagccactgc tgaccttttg
    36601 ttacgccagg cttatttcct gtctgtgcaa ttttcttgcc tactagtcga ttcatcaacg
    36661 tagatttccc aacatttgga atacctaaga ccattgcccg aatagcgcga ggcttgatcc
    36721 cccgagcagc atctcttgcc cgtttttctt tcaatgcttc tttagccgca ggtactagac
    36781 ctttaattcc tttactttct tgtgccgtga tagctaatgc aagatggcct tgtttacgaa
    36841 aatattcttg ccacagcttt gtctgttgtg gatctgccag atccgcttta ttcaataaaa
    36901 caaggcgagg tttttgctga atgatctgat ctagcattgg attacgagaa gataaaggta
    36961 atcgtgcgtc taccaattca aatacgatgt ccacatattt cattttttca gaaacttctc
    37021 gtcgggcttt tgccatatgt cccggaaacc attggatggt cattgttctc tccattcctt
    37081 tcataccgga atattccccg gctttacttg tttttttctt tttcaatata aattcacttt
    37141 tttattataa agaaattcca tctattagtt aagtgaaagt gaaccagtcc tcattctatc
    37201 acatcttcac ttttttgatg atgcaaattt ttattttggt ttctatatat gaatctaaat
    37261 ttttgacagc gtttcctaaa taagagatga tagacgaaca aaacagaaag gagacgaaac
    37321 aaatgaatag tatggttttt gttaattttc ctgttgctga tgtcaatcgt tccgttgctt
    37381 tttatgaaaa gctgggtttt aaaaaaaatg aagaattttc tactgaagaa gctggttcaa
    37441 tggtatggga tgacactttt tggataatgc ttctctctca tgatttttat aaaaaattta
    37501 taaaagataa agaaatagct gataataaaa aaacaagtgg tgctttgatt tcgtttagtg
    37561 ttgaaaatgc ggatgaagta aaaaaatttg ctcaaattgc aaaagaaaat ggtggtactt
    37621 tccacgaagt agatatggga atgcctgaag aagaaatgtt ttcattagaa gtccaagatc
    37681 tagacggaaa tacattagaa cccgtatgga tgaagatgta agcagataac taatctgacg
    37741 ttttttataa caaaaaaaca aaggcggatg atacgataag tattctccgc ctctattttt
    37801 tttattcgta caatctcttt tttacagttt ataaaagcag tcttctcacc ctttttttaa
    37861 ttgttagatg ccagtgtatg taaatcacca atgtgtcatg acacattggt gattttatgg
    37921 tatcctttta ttattaactg acaaaggaga gaatattttg aacactttga ttgcaaaaga
    37981 cgtttttaga ttgcccgaaa tgaatgcaag attgttgtcg acctctgctc ttttattagc
    38041 ccttgatgtc atcttataca agatagcgat tggtcctgct tattttcaaa tcacattcgg
    38101 atttttaagt atggcgctta tgggttatct atatggaccg atctgggctg gtttgcttga
    38161 aatgttgtcg aacactttaa atttcacgat atttggttca ggaacgtttc aagctgcttt
    38221 tcttatcacg gctttccttg gtggatttat taatggctta tttttatatc ataaaaagat
    38281 aaacctgcct tccgtcatcg ctgcccaatt attgattatg atcccagtca gcctttttat
    38341 caattcttgg ctgatgtctg ttttgtttgg tgcagatttc aaagtaattt ttctaggtag
    38401 attcatcagg aatatgatcc aaatccctat tcaaataatg gttgtttatt catttatcaa
    38461 aactttagag gctagaaaag tgtttaaacg agctgtttga ttttacgtac taaggtagta
    38521 aactgatttt ggattaaaca ataaagcgtg cagtctcaac agactgcacg ctttattgtt
    38581 tctcactgga tccattttat ttcatcaagt ggataataga caaatcttgc tttacctaga
    38641 atatcagttt tattgatcgt gccaaacgaa cgactatctt ttgaaactct tcgattatct
    38701 ccaagtacaa aataattatc ttccggaagc ttggattgtc ccgttagctc ttgtagtgta
    38761 aagtccgtcg tataggatgc atttgcatga tctgatttca ggtttttagt tagataaggt
    38821 tccttaacta ctttcccatt gatcttcaat tgatcatttt ggtagctgac attttctcct
    38881 ggaagaccga ttactcgttt gatataaatc gtgccatctg ctaattgaaa aacaacaata
    38941 tcaaatcgtc tgatctccga aaatttttcc atcacaacca tatcaccttg cttcaacacg
    39001 ttttccattg aattgccttc cactggtacc gggatgaata aaaatccccg caacatgaac
    39061 gcaaggaata cagaaacaag taagtatttg aatacaagcc agaagcgatt aatatagcgt
    39121 tgtttttttg tcaatctcta tcaatccatc cctctttttt tcattctttc tttattataa
    39181 gaaaaatatc aaaaaaatgc gactagatag ctgaaataaa aataattctt tcaattaggc
    39241 tattggacaa aaaacttttt tgatcataaa gtacaaaact atctcttata tgtcatgatt
    39301 attttctaaa tatttttccc atgcttcgtc aaagatatcc atggacggca aatagtcgac
    39361 attcagttcc agataattag aaatttcttc gtagctagag ctgtgcttag gaaattggat
    39421 gtctttaccg gcttctgtag cgaaaacaga taaagcatca tgtgtgccac cgcctcgcag
    39481 tgtcattaaa taatgaaaaa agcttcgatt cacccttcgt tcctccaatt ttcttcgata
    39541 aaggcagccc ggcgtgcatg gtttctttta aaattttcag gatgcttttt ataatactct
    39601 tgatggtctt cttctgctag ataaaatggt tgggctggtt cgatttttgt aacgattggc
    39661 tgttcgaaac gtccactttc agctaactgt ttcttacttt tttcagcaat gatccgctgt
    39721 tcttctgtca aataaaagat caccgggcga taattgtcac cgcgatcctc gaattgtccg
    39781 aaagcgtcag ttggatcagt ttgctgccag taaagttcta ctaattgttc atatgaaatc
    39841 aatgttggat catagataat ctccactgct tctgtatgtc cagtcgtttg gctttttact
    39901 tgttcataag tcggatctgg tacatgccct ccagtatatc ctgacatcac tgtatggata
    39961 ccaggaagcg tgtcgaaagg ctggatcata caccagaagc agcctcctgc aaatattgct
    40021 cgttccatta tgattccccc tctaatacta ctcatccgat gattttttat tttcttttgt
    40081 cttgctttca gtactgctgg tgctagtttt gttggtattt gagttgtttg aagcatcaga
    40141 ggtatctttt ggcaaatata gactaaaccg aatgtcatca tttactaagt cgattttatc
    40201 tgctttaata tacatcccgt tttgcattcg gaattgatcc aacctaagca tgatagtcag
    40261 atcatctgta ttgacttcga tccaatctgg taatttatag tttctcttga tcatattcat
    40321 cacatctttg attggcaaac tcaatgttcc gatagaaaga cttctagctt ttagttggac
    40381 atttccgttt tccatcacat acggatcaaa atataaatag aaatcgatag gaaaacctag
    40441 tacttcgaaa gtaccattga gtagtgcttc attttccaaa taaaatttat attcaatatc
    40501 actatctttt tgatactcac taaggaaaaa gctgatgatt tgattgactt tttctttatt
    40561 tgaattgatc gttaagacag gatctccttg tctttccgta agagctggta tttctgggag
    40621 ttctggttcc cgattagcaa aaatacggct gcctaaaaat acggtcgaac caagtactac
    40681 cccaagaagg ataaggaagg cgaatttcca gtaatttgtt ttctttgttt tgtttgaaga
    40741 tacgtcagat cttgttttca tgtttattga tcatcctcct tctctaacca ttggttttgt
    40801 gtctcgatca gctgatctct cactgcattt gccatcaatt gataacctaa attatttgga
    40861 tggaaatgat cttcttcata gagcacatta tttttgatgc catttagatt ttctgtcgtg
    40921 ctagttgttt gatctgttcc ttcttctgtg acacctactt cctgattcaa tccttgataa
    40981 agcaaatcat tgattgggat aaagtagcag ttcggcattt tttttgtcac cgtttctgtt
    41041 cctttgttcc aattgttaac aattgtctgc atgtcagtga tctcaggaaa gttcaaataa
    41101 aatggattgt agatgcctaa aatgtaaata ggtgcggttt tattgaggga tcgaaattct
    41161 tccaatagtt ctgtgacatt ttcctgatag tttttcagtg gctttttaaa ggaattgacc
    41221 gttaacccga ataaattatt ttggataact ttcatcaaat cattaccgcc aacagtcagt
    41281 gtgataaaat cagctgtttt gatattgttt cgaatttctt cttttgtttt tactcgcttt
    41341 aagatctggt cacttcgttc accatttaca ccatagtttt ctgtttcaac cgcggtcaaa
    41401 ttataacggt cttttagatc atttgcgaca aggggaacga atcctccttg cttggtttga
    41461 tctcctactc cttcagtcag cgaatctccg atagctatgt agtgaagttt ttctttttta
    41521 tttggatctt ctctcacagt agttactggt ttcattagtg ggccagcttt cggtatagaa
    41581 gcagctaaac ctgcatagat gatgatcgca attaataatg ggaacaaaac gaggatcaaa
    41641 tgtcgtttcg ttaatttcat tttttcacct cttgtattcg attggttcta atgttatcaa
    41701 aaattttatc aaaaaggtag tctttatgaa aaaagaaaac aattattttc ctaattttat
    41761 aaagaaaaag agaataagct gcaagccttt caggctgagg gcttatcctc ttttcgacta
    41821 atctacataa tacatgattg caaacgcgtc tttaccagta tgcgtagcga taaccggatt
    41881 cgtatgcagt acagggatat gcatgtccgg gaataattct tgcaaaccct ctttgaattc
    41941 ttgcgccaat tcttttgcat ccgcatgtga aataccgatt tgtcgcacat ttggcaattc
    42001 tttcagttca tttttcaaat tattaaacca tttatcgaac gttttctttc ctcgcccctt
    42061 agttacaggg attaattcag aatgggcgaa attcatcacc acgcgtatgt tcaaaacact
    42121 agacagcaaa ccagttgttc ggctgattct tccacctttt accaagttat ctagtgtgga
    42181 tattccgatg tataattttg tattgtcttg tacttttttg acttcttcaa ggattttctc
    42241 tactgtttta ccttcttttg ctaattcagc tgctcgaatt acctgaaaag ataatccttg
    42301 gtcagtggta tcactgtcga taaccgttac tttcgttttt gttagattac tggcttgtct
    42361 tgctgcttct actgttccac tcaagccttt tgtcatatgg atcgaaatca cttcactgcc
    42421 gtcttctcct agctcatcat acatcgagat gaattctcca attggtggtt ggcttgtttt
    42481 gggcagattt tttgctttcg ccatcatttc cataaatctt tcgccgtcta gttggtcatc
    42541 atcgggatat actgttccgt cgatcatgat ggatagcggc atgacacgaa tgcctaaagc
    42601 atcgcgtaca tttttttcca tcgtacatga agaatctgtt acgattttta catttgtcat
    42661 tattttctct ctctctttct ttaacaagat gccttattca tgttaaacta catgtaagac
    42721 aatttctatt tttagtataa cagacaaata atgatttttc attaattaca cctagtaaag
    42781 gagccgtttt catggaaaaa acgaaattta atcgaacgta tgaaatatta aatgaagtgt
    42841 ttaatgcagt cacccatgga attgggactg gattgagtat cgcgggacta gtggttcttt
    42901 tagtaaaagg tgcccacttg cattcctccc tccatattgt ctcttatgct atctatggat
    42961 cgatgatgat tcttttattt ttaacgtcta ctttgtttca ttcattgatt tttacaaaag
    43021 caaaaaaggt gttccaagta ttcgatcata gttcgatttt tcttttgatt gcaggaagtt
    43081 atactccttt ttgtttgctg agtatccgag gatggctagg ttggacttta tttgtattaa
    43141 tctggttgtt tgcgattctt ggcattatat ataaagcgtt gacgttgcat aaacgggaga
    43201 gagtatcaaa agtatctacg atcatctata tttttatggg gtggctctgt gtcgtggctg
    43261 ctgttcctct ttatcactct cttggaatga ctggtgttat tttgatggta gcaggcgggc
    43321 tttcttacac gataggcgca ttcttttata gcttgaattc tatccgctat atgcatgttg
    43381 tttggcattt gtttgttatg ttaggtgcag gttttatgta cttctctgtt ttattcttta
    43441 cttaataaaa aaaataaagc tatggatggg acagctctaa ataacagcta gtctatccat
    43501 agctttttta tatcgtcaat tcgcctgtcc cgctttttac aggattctca ttacgctgat
    43561 acgtttcaaa ttgatgcgga taacgatttt tttcatccat ttctccttga ctagtattga
    43621 tcagtgacca atcagaccag tcaacaggtg gaaaataagc atctccatcg aatacatgat
    43681 ggatgactgt acggtataat atcgtacaaa atggcagaaa ttcttgataa acagctgacc
    43741 ctccagcgat gaaaaagata ccgtctgttt ctttttccag agcaagcacg tcttccacac
    43801 tatgcatgac atgcacgcct tctgctttat aggaagaatc tctcgtcaaa acaatcgtct
    43861 gacgattcgg caacggacgg ctacccatcc cttcgaatgt ttttcgtccc atcactagtg
    43921 tatttgcttc tgtcatttgt ttgaagaatt tcagatcatt tggcaaacgc caaggaagac
    43981 ggtcttcttt tccaatcaat ccgttttcat cctgtgccca aattgcagct aacattttct
    44041 catcctttct gattctaaac agcgatagga gctttgatcg ccggatgtgg gtcatatcct
    44101 tctaattgga tatcttccat ctcaaaatca aatactgact gcttttcctg attcaaaact
    44161 aaagtcggaa atgcgcgtat ttctcggctc aattgttctt tcatttgttc gatatgattg
    44221 atataaagat gagcatctcc taatgtgtga acaaattcgc caaccgctaa acctgtttca
    44281 tgtgcaatta ggtgagtcag caacgcataa cttgcaatgt tgaacggaac gcctagaaac
    44341 acatccccac tgcgttgata caattggcag cttagccgtc cctcttgaac ataaaattga
    44401 aacatcgtat gacaaggagg caaagccatg ctaggaacat cttccggatt ccatgcagaa
    44461 acgatcaatc ttctagaatc aggagtcttt ttgattgctt cgatcacttg tttgatttga
    44521 tcgataaagc caccgtcttt tgtttcccag tgacgccatt gatagccgta gatgtgtcca
    44581 agatcgccgt atgtttcagc aaaggaatca tcggttagga tcttctcgca aaaaagcttg
    44641 ctctgctttt tatattcttc attgaattca ggatctgtca aacatctatg gccaaaatca
    44701 gtcatatctg gtccattata gtctggactt ttgatgtagc gttcaaatgc ccattcatcc
    44761 caaatatggt ttttattttg taatagatag cggatattcg tatctccttt taaaaaccaa
    44821 agcaattcgc ttttgatcaa tccaaaaggt actcgtttcg ttgttaacaa aggaaaccct
    44881 ttttgcagat caaaccgcat ttggtatccg aataagctta atgtgcctgt gcctgttctg
    44941 tcttctttac gatgcccttc ttccaacaat tttcttccta agtcaagata cgcttgttcc
    45001 atcctttttc ctcctaatct tctacccatt cactcaagta ttcccaccgt gccatttttt
    45061 cttcaagttg tgcttctgtt tcagatacgt cgttttgcaa ttcttgtaat cgagtgaaat
    45121 tatctccttg atgattcatc tcttcttgga gcaatgagat tttttcttca agttctgcaa
    45181 tctcatcttc aatcgtttcc cattcttttt gttccatgta agataatttc ttcttttcag
    45241 caggttcctt gctctgtatt tttggtttcg ctttttcagc aggctgctgg gtctcttttt
    45301 gcttcagtaa ataactggac atgtttccgt aataaagttc ttgttttccg tttccttgga
    45361 atactaataa cttatctgct accttgtcca agaaataacg gtcatgggaa acagtgatca
    45421 cagcacctgg aaaacttcta aaataatctt ccaaaatcgt caatgttgct atgtccaaat
    45481 cattggtcgg ttcatccaat aataaaacat taggttgctg aatcagcagt ttcaacaaaa
    45541 ataaccggcg tttttctccg cctgaaagtt tgcctatcag tgtcccatgc ataaatcttg
    45601 gaaataaaaa tcgttcaagt aattctgcta ctccgatttg actgccatct gctgtttttg
    45661 cttcttcagc agcttcttgt aagtaagcaa tcatccgttt atctggtgcc atttcttcat
    45721 tttcttgtgt ataatacgca agatgaaccg tttcaccgat agacattgta ccgctatcca
    45781 ggggaattct gccagctaga atattaagca atgtcgattt tcccgcacca tttttaccag
    45841 taatacctag tctttcccga gattgaatca ataaatctaa atgttctagc agtgtttggt
    45901 catttatacg gtaactgcca tctttgattt ccagtacttt tttccctaaa cgttgtgtcg
    45961 ctaggttcag ctctaaatca tcttcttggt ttacttggta caagttctcc tttagatctt
    46021 cgaaacggtt gatccgtgct tgctgcttgg tgccacgtgc ctgtacgcca gccctcatcc
    46081 aagctaattc ctgtttataa agccgcttgc gcttttcttc ttgttctact tctacacgat
    46141 cacgttctgc tttttctaag acgtaagctt cataatttcc tttatactcg tataattttc
    46201 caaatgaaag ttcgaagatt cggtttgcta ctctatctag aaaataacga tcgtgggtaa
    46261 ccatcaatag tgcgccacgg tattgtttca aatagttttc caaccactcg atcgcttcat
    46321 aatctaaatg gtttgttggt tcgtctagta atagtaaatc gggttcatca atcaacactt
    46381 gcgccagact aactcgtttt ttctgaccac ctgataaagt actgattttt ttatctaatt
    46441 cactgattcc taatttttgc aaaataatct ttgcgttggt atctgtagtc caagcatctt
    46501 ctttattcat ttgttcttct gctttagcat aacgtttttg cacatcaggg tcttctccgt
    46561 tttcccctag ttcgatcaat gcttcctcat atgctcgaac agtttggatc aaggggctgt
    46621 ttccttgaaa gactgcttgg agaacagtta attcatcgga aaattcagct gcttgagaaa
    46681 gataaccaat acggtaatca gttggataaa acactgtttg ccgatcaccg tcgctgctat
    46741 cgataccggc aataatattt aagagacttg ttttacccgt cccgttcgtc ccaatcaacc
    46801 cgatacggtc tttttcgtgg accaaaaaag aaatctggtc aaacaaatct ttttcaccat
    46861 aagttttttt gaggtcagtt acttttaatt ctttcaacat gttccctcct tatcttggat
    46921 attgtatcat aaaaatagtg aacttcagga aaattttttt ggtatttgtt ctttttgtgt
    46981 tctcaaaaaa agaacaggac cgattcgatc ctgttctgat atgttttgtt ttttataaaa
    47041 cttgaaaatt tttacctttt tattttattg gactcgtttt ttttgacttt gctcgaaacg
    47101 caaatcggaa agaaaagtta tcagatggtt tgttcatcgt ataagattct aacaaattga
    47161 tattcctgcg atagctgttc gcagaaaacg tcgtgatttt ttcagcaact tcgtattcat
    47221 caatgatttt tctttcaaga taataacctc ttagcatttt tttcgtaaac agactatctt
    47281 gctggatcat ccacgaagaa atcaaattcc ccgagttcat ttttattcct tcaagtttgc
    47341 gttgctggat aaaaaattga accatcgttt catcataaat atcagtcaag ttatctaaac
    47401 tttcaataat caactgagta tttttttgat atgtctctct gatttcttgg atatcttcat
    47461 cactaataaa tgtctgacga tcagcatatc ttctttgcca aaacattttc ggatggagaa
    47521 cgattcgcat taacctacgg acaacaatga accaaaagcc gataaaagac aaaatctggc
    47581 ttgtgataga atgttcgaat cgagaaagaa aacgggagta aaaacgataa ccattagaag
    47641 aaagcttgcc cgaacgataa ctttcatcca atccatcccg ttcgatcgac aaaatcagtg
    47701 cttgtatttc ttgtacttct tgcttttcat catcggttaa atcttccaag tacagatcac
    47761 gtatccgttc ttgataattt tctatcactg cttcagtggc taaaaattct tttgtattac
    47821 gatcaatttc ctttatttct tttcgcaaaa cttcaacgac ctcttctaaa atcatcaaag
    47881 cattcaaatc cgtgcttttc gcttcctctg tttccgtcag cataggcaag acaatgatcc
    47941 ctatgaccaa agtcactaag atgacacccg ccgtcagaaa caaaagcaaa gaccgctggt
    48001 aaaacatcat attattgatt gaaaatggca aaataaaaat cgtagccaaa ctgactgttc
    48061 cctttacacc gccaaatgtt aagatcaaga tctcgttcaa ctgttttttg aactttttac
    48121 tgccatcttt gaatacataa aaaagactga tagaaatgaa tctgatcaca aaaagcatga
    48181 cagagattaa tacgataatc gctaataaaa gaccgtttgg atataaaccg tctccccata
    48241 ctggcgagaa cacttgcgtc aattcgattc ctaaaaatat aaatactaat gcattcagtg
    48301 taaaagcaat agttgtccat gtactgtggg acaagctcga caattctgca tcaaacacag
    48361 agattttcct aaaaccagaa gcttggagaa tacctgctgc cactgcagca atgattccag
    48421 atacatcaaa tgcctctgcc aatacatagg ctagaaaagg aagcaaaagt tcgatcagca
    48481 gataccctgt gacatcttgt gctgatgctt tttcgatcaa atgaattatt ttttgtttga
    48541 accagacaag caaaaagccg atcaaagctc ccccaatact agaaactact agactcatcc
    48601 ccgcgtttac tgctgaaaaa gatccggtga tcagcgcacc aagagcaaac tggaaggcag
    48661 taacaccaga tgcatcattc aaaagacctt ctccttccaa aatatgcatc gcctttttag
    48721 ggatattcac tcgtccagaa agagaactga ctgctaccgc atctgtcgga cctaacgctg
    48781 ctccaaaagc aaagcaggca gcaagtggga cacttggcaa caggaatgat aacgtcgcac
    48841 ctaccccgac aagggtcaaa atgactcctc caaatgccaa gaacaaaatt gtcccgaaat
    48901 ttttgagaat cgaagaaata tctgcttttt ctccttctct aaataacaat ggtgcaataa
    48961 tcataactaa gaacaattca ggttcaaaat cgattgattg tccccactct gtcagaccta
    49021 ataccactcc aaggaaaatt tggatcagtg gagctggaat cattggcaaa atgcggctag
    49081 ctatgttcga taaggtgatc gttactgcaa atacaataac taactcagca aattccatcg
    49141 tccatcccct ttatttttta ttttgtgtaa gcatttttaa aaattgttct tttttcttta
    49201 aaattttggt ttcgactact tcaacctgtg tttggttccc ctctaattca cactgtacac
    49261 gttttgactc caaacgaagc agatcatgtt tcagacgttc caactgacga tacatcaata
    49321 tatttctttt acgcaactta caaagtattt gacggcggtc atccatcgaa agggcgccat
    49381 agcgatcatg caacagtttt ttttgttgtt caaaactctc tctcattttc cagatctcct
    49441 atacacaaac ttccatcatt atagcaaagt tctttttgga tgaaaaatat ttcattgttt
    49501 catcgtttat tgctagttag aaatttccat aaatttttca acgcctcatt ctattccaaa
    49561 tagtatcaga tatcaagtaa aacttaagaa agataaaagt ttctgacaaa aggatgttta
    49621 ctttcccatt cctgcctttc ttgttctttt atcacaacaa aaaaatgggg ctgcgacaaa
    49681 aatcttgtca cagtccctta ttctgaataa acggtgtgga agagacagcc tatcagtagt
    49741 aataagacac atctctttca cagcctcatt tttgcgtaaa aatcgattta ttcgaaaaat
    49801 tccccgtata catcttctac acgttgatct ggattgatca cgatatacaa gttacctgtt
    49861 ttttcgctga tttttgttga ttgatattga ttgtctaatc cttctgttcc tttatctaga
    49921 tatgggaagt acacaagatc aggtgtgcca tttcggtaaa ggatttccat tcgctcgata
    49981 tcttcgtatt tcaatgcgcg attaaacatg cccatttcca gtccgcctag gttgatatca
    50041 tgtgtcgcaa ctgcgtcccc ttcatggaag atttcgattt taaatccagc acacggatgg
    50101 atttcaacaa attcactgcc attgattcgt ccaaaacttg ttgtgatttg tttgatccaa
    50161 agatcgccga tatgacggcg gttgatcgtc caggtttctc catttctaaa ataaaatttt
    50221 agcgctgtca tttctttact cattaaaaag actcctttat gatgtaattt attcttgtac
    50281 tacctcagtt tagcacaaat ttatgtaagt ggtcacatct tatgtttttt cttctaatga
    50341 cgtatctgcc cactttaagt agccaacaaa gctgagcaga tacagtctag tgttttttaa
    50401 atcaattttt ctttcgataa aaaatccaaa acctgttttt tatcattttt tattctttgt
    50461 tctacgacgg ctttttcagc taattgcaaa gcttcactaa cccacttacc aggttttttt
    50521 ccagtttctt ctagcaagat tttaccatct actgctaatt cgcttaatga cttgataggt
    50581 aaacgatcat aggattctcc tacggcatcc atctgaggtg tttcgtcaaa atagatcatc
    50641 aattcttcta cttgcagtgc atgttttttg cctaagaagt acaattcgaa tggttccaaa
    50701 gctccagttt ctcgttgtcg tagtccttgg acaagtgctt gaacgtcttt aatcatttgg
    50761 ttagaacact tccacgattt caaaaaggaa cgaatctcat tttcttttag atccagttgg
    50821 ctgatcaata atgcccatgc ttggctctct tctttcaatg ggacggatgg taattcagca
    50881 aaacgtaaaa gtgcttcgcc ttcttctttc aaaccgggac agcaaatgta gcactctgtt
    50941 tcaataaatg catggattcc cgcggcccgt tcatttccca agagcatctt gatgaattcc
    51001 acatttatac gttctacaga tattttacct aatagctcgt ggttttcttt gatggcgtag
    51061 aaggtttctt cctctaattt gaaccctagt tgactgacaa aacgcaaccc gcgcatcatt
    51121 cgtaaggcat cttcatggaa ccgctcatga ggattgccta cagctcgcaa gatctgttct
    51181 tctagatctt gcagaccatc gaacaaatcg atgatttctc catcttcttt caaagcaaac
    51241 gcattgatcg taaaatctct tcttttcaaa tcttctgcca acgaacgaac gaattcgaca
    51301 tgatctggtc tacggtagtc ctgataagtt gattccgtcc gaaatgtggt gatctcatat
    51361 tgttcatcat tttctaatac caacacagtt ccatgttcga tcccaatatc tatcgttttt
    51421 ggaaaaagct gtttgatttc ttctggaaat gcgcttgttg cgatatccac atcatggatt
    51481 ggctggttca gcaagatatc acgaacactt ccacctacaa aataagcttc atatcctgca
    51541 ttctctaatt ttttcagaac tggaattgcc ttttggtatt ccagaggtaa ttgttttaat
    51601 ttcatttttc caacctttcc tgcgtgtttc ttgtcctgag ataaagactc agttgcatgg
    51661 tgactgtttg acaagtccgt ttcagagtct tcaaggccag gaccacttca tcttgtttac
    51721 tcgtccttac gctcaaagcg attatggtct ctttgattga atttttccat gtttttttca
    51781 aaaacttcag ttaagtcgat attcaatgaa ttagccatga tcatcgtaac gaataaaaca
    51841 tcaccaagtt cttctgctac cgagttaact ggttcagaag cctttttgct tttttctcca
    51901 taagtgtggt tgacttctct tgccaattca cctacttctt cagttaatcg agccatctga
    51961 gctaatggag agaaataccc caccttgaat tgctggatat attcatccac ttcctgctgc
    52021 atactgtata aagaacgctt tttatccatc tttttccctc caaaactatc ttaccaaaac
    52081 tttaacgcaa atcctagata agagcaattg agaaaatcga atttccatgc tacatttagg
    52141 aaggaatttc taaatggaaa ttctgtgaaa atacataatt gaaagctgga attcatatgg
    52201 tcaaacgaaa aacagtaaaa gaagttcttt ttatcattat aggaacaagt atttatgcat
    52261 ttggtcttgt ttacttgaac atcgctaatc atttagcaga agggggagtc tcagggatca
    52321 ccttgatctt aagagcttta tttggtattg atccagctta tacgacttta ttaatcaaca
    52381 tcccattgat tttactagga ggaaagatcc tcggtaaacg ttccttggcc tatactgttc
    52441 taggtacact ttctttgtca ttctttttat ggatctggca aagggttcca ctagaaatca
    52501 atttacagca tgatctactg atcgtttctc tacttgcggg tttagttgca ggtgtaggaa
    52561 gcgggatcgt ctaccgcatg ggtggaacaa caggcggcag tgatattatc gctcggattt
    52621 tagaacaaaa ttacggcatc actatggggc gttccctatt ggcatttgat atcatcgtct
    52681 tacttgcttc attaacctat atcgacttga aacgtatgat gtatacgttg attgtttcgt
    52741 atgttttcag tcgtgtgatt gattcgatct tagatggcgg atattctgca aaaggtctac
    52801 ttgtcgtctc caacaaaagc gaagagattg caccactact gatgaccggt ctgcaaagag
    52861 gtgtgacttt cctttctgga gaaggcgcat tctctggtaa ttcaaaaaaa atcatctata
    52921 tggtcgttag ctctagtgaa ttaactgaag ctaagaggat cgtccacgag attgacgaaa
    52981 aagctttcct ttcaatcatc aatgtgcatg aagtggaagg gcaaggcttt acttatttga
    53041 agccacagac aagattactg aaaaaactat aagaaaaaag acaaagatag gctatgagga
    53101 aagattccac atccagctga cctttgtctt ttttagtact atactatttt taactaattg
    53161 ttatgttcac ttacccggtt acttttcttt tgtgtctgca aaaggatctt tcggttaact
    53221 tcatcagata atttcaaaaa agcatcccta tctccatctt ctagtgcttg atcgatttga
    53281 gcataaagca tttttagttt tgcctcttct tctttttctt gaaaatatcg ttcaattaat
    53341 tcagtatctt cttcactgac tgaagaatcc caagaagaaa atggattgtc ttctaagata
    53401 gatagatatt ctcttgtctg ccaagcattt tcgaatatac attccacata taaaggcttt
    53461 ttccaattca aacggatttc atgaaaaatc tggtctgtgt ccgtaaattc ttttccctgc
    53521 aaaaacaatt tcatgggttc cccttcaaca gatagatcac tgatctgcag tcctcgatcc
    53581 gcaaaattcg ccccttcaac aaagtggaca ttgcttaaaa tcgcttcatg attggcaaga
    53641 taattcaaga tccaaaaaac ttctcttcgg ctaaaagata catgattgac catccacgtt
    53701 aaaaaattct tcttttcccg tacatcaatt agcatttttc tcacctctct gttaggtcat
    53761 ctaataatga cagtgcctcc atatctcctg gttcaagtgt taaataataa gtcaataatt
    53821 cttgcgctct tttcagctgc ccttcttctc ttaagaaaaa ggcatactct ttcaagaaat
    53881 ctggttcatg tgatagttca tgataagcct gttcatagtg tacagctgca acggtaaagt
    53941 cttctaattc attataagca tgggctaggt tccattctgc ataaggatta gcagtttctt
    54001 ccatctgatt gatcacttgt atcacatctt catatctttc atcatccaag taaagattac
    54061 ttaaagtaag taatgtttca tcttgtttgt ctcctacttc taaagctttc agtaaaagtt
    54121 cttctgctcg ctgtctatca tgcagacgga aagcattttc cgaggccagg tgataaagtt
    54181 cgacttggta aggattttct ttgattcctt cttctaacac tgtttgtgct tcttcaatca
    54241 tttcttcttc ttgaagagct tgtcctagat atagatataa cgattgataa tgcggattaa
    54301 cttctcgaag ttcttccaga tagttgattg cctgctgatt ttctttcaat tgaagattcg
    54361 taaaagctag ctggaacagt cgatcatctg tcctttcttc tttcagtgct tcttctaaag
    54421 gtacgatagc tgcttcgaat tctccttgca tacttaagga ttgtcctaaa cgttcctgca
    54481 tcgagattcc tgaaatttca tttatcccgc ttgccaacaa tgtttcataa accactgctg
    54541 cctctttgaa acgatcaact gaaaaataca attcagctag cgcaaactgg atcaatggtt
    54601 catcaggaag caacccagct gcttctttca attttgcttc actcacttca gggattccga
    54661 taacttggta caaatcagct atcgccaata agctttgcgg atagtaatca ctttgcttat
    54721 ccactttttc caggtattca aaagctaagt cgatctcatt atcttcgatt gcaatttctg
    54781 ctaacgggat gttcagtccg tcattttctg ggtattggtt gatcagttgt tcaaaaatct
    54841 gttttgcttc gatcaaaaag ccaatagcca gcaattcttc gcctagttca gctaatatat
    54901 ctgctgggtc ttcttttaat gctttttcta aaaagatttg tgcttgtgac aagtcttcat
    54961 ctgataaagc ttgcaacatt ttttcgctat ttgtattcat ttcaattccc tcttatctca
    55021 ctgacgattt gttgaaatac cgtcattgtt ctcaataatt ctttttcgtt tggatgttgg
    55081 tatccgtcta ttatacctat tttttctaaa acaagtattt ttttgctttt ttctgccaaa
    55141 aaaagaactt tttccaaata ctccatcttt gaaatctgtt ccagccagtg gattggatag
    55201 ccaagcaagt ccagccacac aaaaaagttt tttagttgga aatcaaaagg atatgcttgg
    55261 agattccaca cgaaatgaaa catcattcct aaaaattttt tcatactagc agaaagtaga
    55321 tggccatttt cggtcagata aaaagcttgt tcaaacagtt taccataatt tgacaggttt
    55381 tctgcctcta attgataaaa atagatcatt tcttcgatca tcccggcaaa cggccgagtc
    55441 gttaattgct ttttatttgg atagttttta tacagatttt gcaaaaaacg atgatcacaa
    55501 atcattccgc aacagataaa agtcaaaaag tcaatctgct ttccgtccac ctgccgctcg
    55561 ctgattgttt gatcataaac gatgcgttct ggcagattga tggtttgcag cactacacga
    55621 tttggtagct gcaaaatcgt ccgctgcggt gttaatgctc ggcttagaga acggatcgat
    55681 acagggatca tccatagtga tgaatcaagg gttgtatgtt tttgaaaaaa acctgccaga
    55741 tccatgatcc cttcatttcc aaatccgatg ataaacatgg attgattttc gggatagcgt
    55801 ttgacgaaat caagcaggtt ctttaattct gttaaatgat tgcattgagt gttggcacaa
    55861 atataccagt cattgtttgc ttgatttgca aataacgggt tgatcttatc tgcaaacaaa
    55921 tcataatagc gctgattcgt taaaaataag attggctgat caatggaaag ttctcttagc
    55981 tgactgacta gcgtttctcc gtaaaacact ttcgtcaacg catcttctac ttgataatca
    56041 agttccatac gcatccctcc tcttcttatt tttattttac cattagtaag caaattctag
    56101 aaaagataag agcaaagctc acctcataac ttgcaaataa ataaaaatta aataaaatac
    56161 atgtgttttc tatgtatgac atacggattc ggaatctctg tctcttattt attccttttc
    56221 tgctaggaaa taaaaagaaa agcacttgta gccctagagc cacaagcgct ttttcaactg
    56281 tcttatttaa cagcgtcttt taatgcttta cctggtttga atgcaggtac tttgctagct
    56341 ggaatttcga tttcttcacc agtttgtggg ttacgacctt tgcgagctgc gcgttcgcga
    56401 acttcaaagt taccaaaacc gattaattga actttttcgc cgttagctaa agcatcttga
    56461 atagttgaaa atacagcatc tactgctgca gttgcatctt ttttagttaa atcagtagct
    56521 gaagcaactt tttcgattaa ttctgctttg tttgccatgg atagattcac ctcctccaca
    56581 agagatatga tagaaatatc atttagttaa aactttctga gtggtccaga agtttaaaaa
    56641 gaaatattga ttaacttcaa tattctgtta tcacgatatc atatgaaccg cttaatagca
    56701 aggtttttac caattttcac atgctttttt tagtcataga aacgtaacaa acgaaactgt
    56761 ctttttcttt tgaaaaaaaa acgtcgatat ggtaaaatgc ctattttctc ctacgaggga
    56821 taattcggat ggacgtccct tcaaaagtaa atgcttttct gatttgattt tctaagaaac
    56881 gttcataaga aaaatgcatc aattcctctt cattgacaaa aacgacaaat gtaggtggtt
    56941 tgacagcgac ttgtgtagca taaaaaatct tcaggcgttt tcctttatct gttggtgttg
    57001 gattgattgc tacagcatcc ataatgatat cattcaacac agccgaagag atacgaagat
    57061 tctggttcat acttacttgt tcgatcattt caggcagacg ttccaaccgt tgtttagtca
    57121 ctgcagaaac aaaaacgatt ggagcgtaat caagataccg gaattcatca cgaatctctt
    57181 gttcgaaatc acgcattgta ttggtttctt tctttacaag atcccattta ttcacgacga
    57241 taataattcc acgaccagct tcatgggcgt aacccgctac tcgcttgtct tgttcccgaa
    57301 tcccttcttc agcattcagt accatcaaaa cgatatcaga acggtcaatg gcacgcattg
    57361 cacgcatcac gctgtatttt tcagtatttt cgtatacttt tccgcgttta cgcataccag
    57421 ctgtatctat cattaagaat ttctgaccac tttcagaaac gaagtgggtg tcgattgcgt
    57481 ctcgggtcgt tccttcaata tccgaaacaa ttacacgttc ttctcctaaa atcgcattga
    57541 tcaaagagga tttaccaaca tttgggcgac caatcaaact aaacttaatc gtgtcgtcgt
    57601 cctcttcttc agtctcttca gagaaatact tcactgcttc atctaaaata tcaccaatcc
    57661 ctagtccatg gcttcctgaa acaggataag gatcgcctag ccctaaggaa taaaattcat
    57721 agatatcgtt tctcatttct ggattatcta ctttattgac tgctaaaatc actggtttat
    57781 tacttctgta taaaattttc gcaaccatct catctgcgtc tgtcacgcct tcgcgtccgc
    57841 tgactacaca aatgattaca tctgcttctt caatcgcgat ttctgcttga tgcttgatct
    57901 gatccataaa aggttcatcg ccaagatcaa ttccgcctgt gtcgatcacg ctgaattctc
    57961 gacctaacca ttcacctttt gcataaatac gatcacgagt tactccagga gtatcttcga
    58021 caatcgagat acgctcacca gcgatgcggt taaaaatcgt agacttaccg acgttcgggc
    58081 ggccaacgat tgcaattgtt ggatttgcca tattatttcc tcctcacaag tttccaatct
    58141 cacttagttt aacgaatgca ttgccaactt tcaagcatag attgtcaatt aaacgaagta
    58201 tttttattcc ttattgaaat actaatcgct tttcaaaaga aaa
//
LOCUS       DACCVZ010000009        53720 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.009, whole genome shotgun sequence.
ACCESSION   DACCVZ010000009 DACCVZ010000000
VERSION     DACCVZ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.009"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            160..840
                     /locus_tag="IVW63_000536"
     CDS             160..840
                     /locus_tag="IVW63_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP7858839.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            930..1964
                     /locus_tag="IVW63_000537"
     CDS             930..1964
                     /locus_tag="IVW63_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAP7858840.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1978..2313
                     /locus_tag="IVW63_000538"
     CDS             1978..2313
                     /locus_tag="IVW63_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858841.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2297..4777
                     /locus_tag="IVW63_000539"
     CDS             2297..4777
                     /locus_tag="IVW63_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858842.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            4833..6392
                     /locus_tag="IVW63_000540"
     CDS             4833..6392
                     /locus_tag="IVW63_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7858843.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6389..7753
                     /locus_tag="IVW63_000541"
     CDS             6389..7753
                     /locus_tag="IVW63_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP7858844.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7924..8994
                     /locus_tag="IVW63_000542"
     CDS             7924..8994
                     /locus_tag="IVW63_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7858845.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            9009..9677
                     /locus_tag="IVW63_000543"
     CDS             9009..9677
                     /locus_tag="IVW63_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7858846.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9697..10275
                     /locus_tag="IVW63_000544"
     CDS             9697..10275
                     /locus_tag="IVW63_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7858847.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10676..11587
                     /locus_tag="IVW63_000545"
     CDS             10676..11587
                     /locus_tag="IVW63_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP7858848.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11965..12882)
                     /locus_tag="IVW63_000546"
     CDS             complement(11965..12882)
                     /locus_tag="IVW63_000546"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HAP7858849.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            13084..13521
                     /gene="zapA"
                     /locus_tag="IVW63_000547"
     CDS             13084..13521
                     /gene="zapA"
                     /locus_tag="IVW63_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAP7858850.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13579..14127
                     /locus_tag="IVW63_000548"
     CDS             13579..14127
                     /locus_tag="IVW63_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HAP7858851.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            14242..16602
                     /locus_tag="IVW63_000549"
     CDS             14242..16602
                     /locus_tag="IVW63_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAP7858852.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16689..17003
                     /gene="trxA"
                     /locus_tag="IVW63_000550"
     CDS             16689..17003
                     /gene="trxA"
                     /locus_tag="IVW63_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAP7858853.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            17185..18963
                     /gene="uvrC"
                     /locus_tag="IVW63_000551"
     CDS             17185..18963
                     /gene="uvrC"
                     /locus_tag="IVW63_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAP7858854.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            19108..20007
                     /locus_tag="IVW63_000552"
     CDS             19108..20007
                     /locus_tag="IVW63_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7858855.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            20000..21262
                     /locus_tag="IVW63_000553"
     CDS             20000..21262
                     /locus_tag="IVW63_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7858856.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21423..23321
                     /locus_tag="IVW63_000554"
     CDS             21423..23321
                     /locus_tag="IVW63_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAP7858857.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23651..24369)
                     /locus_tag="IVW63_000555"
                     /pseudo
     CDS             complement(23651..24369)
                     /locus_tag="IVW63_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
     gene            24706..25038
                     /locus_tag="IVW63_000556"
     CDS             24706..25038
                     /locus_tag="IVW63_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858858.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            25025..27028
                     /locus_tag="IVW63_000557"
     CDS             25025..27028
                     /locus_tag="IVW63_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAP7858859.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            27047..27517
                     /locus_tag="IVW63_000558"
     CDS             27047..27517
                     /locus_tag="IVW63_000558"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAP7858860.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27538..28122
                     /locus_tag="IVW63_000559"
     CDS             27538..28122
                     /locus_tag="IVW63_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HAP7858861.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            28137..29123
                     /locus_tag="IVW63_000560"
     CDS             28137..29123
                     /locus_tag="IVW63_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HAP7858862.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            29113..29424
                     /locus_tag="IVW63_000561"
     CDS             29113..29424
                     /locus_tag="IVW63_000561"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAP7858863.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29446..31227
                     /locus_tag="IVW63_000562"
     CDS             29446..31227
                     /locus_tag="IVW63_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HAP7858864.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            31220..32596
                     /locus_tag="IVW63_000563"
     CDS             31220..32596
                     /locus_tag="IVW63_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAP7858865.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32603..33238
                     /locus_tag="IVW63_000564"
     CDS             32603..33238
                     /locus_tag="IVW63_000564"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAP7858866.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            33268..34623
                     /locus_tag="IVW63_000565"
     CDS             33268..34623
                     /locus_tag="IVW63_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAP7858867.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(34815..36209)
                     /locus_tag="IVW63_000566"
     CDS             complement(34815..36209)
                     /locus_tag="IVW63_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAP7858868.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            36301..37272
                     /locus_tag="IVW63_000567"
     CDS             36301..37272
                     /locus_tag="IVW63_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAP7858869.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            37269..38051
                     /locus_tag="IVW63_000568"
     CDS             37269..38051
                     /locus_tag="IVW63_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HAP7858870.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(38220..38591)
                     /locus_tag="IVW63_000569"
     CDS             complement(38220..38591)
                     /locus_tag="IVW63_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAP7858871.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            38725..39168
                     /locus_tag="IVW63_000570"
     CDS             38725..39168
                     /locus_tag="IVW63_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAP7858872.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(39211..40020)
                     /gene="yidA"
                     /locus_tag="IVW63_000571"
     CDS             complement(39211..40020)
                     /gene="yidA"
                     /locus_tag="IVW63_000571"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAP7858873.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(40039..41406)
                     /locus_tag="IVW63_000572"
     CDS             complement(40039..41406)
                     /locus_tag="IVW63_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP7858874.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(41390..42220)
                     /locus_tag="IVW63_000573"
     CDS             complement(41390..42220)
                     /locus_tag="IVW63_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAP7858875.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            42383..42820
                     /locus_tag="IVW63_000574"
     CDS             42383..42820
                     /locus_tag="IVW63_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAP7858876.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            42896..43516
                     /locus_tag="IVW63_000575"
     CDS             42896..43516
                     /locus_tag="IVW63_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HAP7858877.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            43705..44211
                     /locus_tag="IVW63_000576"
     CDS             43705..44211
                     /locus_tag="IVW63_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HAP7858878.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            44228..45127
                     /locus_tag="IVW63_000577"
     CDS             44228..45127
                     /locus_tag="IVW63_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAP7858879.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            45214..46098
                     /locus_tag="IVW63_000578"
     CDS             45214..46098
                     /locus_tag="IVW63_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAP7858880.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(46290..46361)
                     /locus_tag="IVW63_000579"
     tRNA            complement(46290..46361)
                     /locus_tag="IVW63_000579"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46326..46328),aa:Arg,seq:ccg)
     gene            46421..47755
                     /gene="rpoN"
                     /locus_tag="IVW63_000580"
     CDS             46421..47755
                     /gene="rpoN"
                     /locus_tag="IVW63_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAP7858881.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            47958..48995
                     /locus_tag="IVW63_000581"
     CDS             47958..48995
                     /locus_tag="IVW63_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SorC family transcriptional regulator"
                     /protein_id="HAP7858882.1"
                     /translation="MLDEIKMIESVAPDIIEVLQERYKILRNIYWMQPIGRRSLSESM
                     GITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSLENFMDQLLGTHQTEQQLA
                     EYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEGENIIAVMGGTTMAVVAEQ
                     LSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKANGNHRALYVPEQLSLATYN
                     SLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEKELVMLKQANAVAESFGYF
                     FNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAIRAYMKNAPKQTWLITDEA
                     AANEILKGVTL"
     gene            49036..50037
                     /gene="gap"
                     /locus_tag="IVW63_000582"
     CDS             49036..50037
                     /gene="gap"
                     /locus_tag="IVW63_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAP7858883.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            50147..51337
                     /locus_tag="IVW63_000583"
     CDS             50147..51337
                     /locus_tag="IVW63_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAP7858884.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            51441..52196
                     /locus_tag="IVW63_000584"
     CDS             51441..52196
                     /locus_tag="IVW63_000584"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAP7858885.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            52312..53610
                     /gene="eno"
                     /locus_tag="IVW63_000585"
     CDS             52312..53610
                     /gene="eno"
                     /locus_tag="IVW63_000585"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAP7858886.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        17826 a         9357 c        11351 g        15186 t
ORIGIN      
        1 ttaataaaaa aggaagaata ttcatgtaaa cgattttatt gtttttttct cttttataca
       61 aaaagggtca taatttcaag taagcggatg aattcatgag gattttttgc atactgtctc
      121 tactatactt aggtcactaa gaaaaaggag tgatttatta tgaaaaagaa catgattggg
      181 acattattac tttcaacact tcttctaggc ggcttggcaa caccagcttt tgctgagggt
      241 caagcgactt caaaaggaga tattaccttt actgaaccaa caaataccgt ggagcctctt
      301 aaccctactg atccttcaaa accagtagag ccagcagatc cggaaaatcc agcaactggc
      361 cagacaggtc ctttaacact ggatgtagtt cccgaattgc catttggtac acacgagatt
      421 gaaagcggaa caaaaacgta tcaagtagac gcttcaaaaa acgatacacc ttatctccaa
      481 gtatcagatc gtcgaggtgt aggtgcagat ggccaagcac aagggtggaa cgtgacagtt
      541 tcggtttcag attttgtaaa cggttcacaa gttttgcaag gcgctgaatt agattttgga
      601 acatccactg ttaaaagtac gtcagataac gaatccactg gaccaactag tcaaactgta
      661 actgggttga gtaaagcaag tgcagcgaca ccaatattta cagcagcaaa agatcaaggt
      721 ctgggaacat ggctttctgt ttatgatcca gcaaatatca cactgaaagt gccgaaagca
      781 gcagctggaa cattcacggc tgatttgact tggaacctcg tggctggccc agtagcatag
      841 agtatgaaat aaattcaaca aactgcggtg aaaatactat aggtgaagga ttttttaccg
      901 cagttgttgt tgaaaggatg tggtggacaa tgaatcaaag taaacgactg tttgtttcgt
      961 ttttttctat tttaagtcta tttttcattt ttccgtcaat cagccaagca aaggattcag
     1021 caggagactt tggaatcaaa ccggtatttc cagagaacca aatagataaa gcaatcggtt
     1081 attttgattt attagtggca ccggaacaaa atcagacact agaagtaatt atcagcaatt
     1141 cttcagatga agaacgaaca tttgaggtct ctgtcaatcc ggcggtaacg agtgatggtg
     1201 gaacgatcga ttatagtcaa aaaaacccaa cgttagatga gacattgccg tttgatgtcc
     1261 gtgacgtttt gctcattgcg aaaaaggaaa tcaatgtatc agcacatgca gaaacaactg
     1321 tacctataga agtgaaaatc ccagcaaaaa gctttaaggg acgtgtatta gcgggtattc
     1381 atgtttcacc taaagaagaa gctgaaacag aaaatgctac agaaggagca caaatcaaaa
     1441 atcgtattgc ttataatctc gcagtcgttt tacaagaaag tcaagagacg atagaaccgg
     1501 atctgaaact tttatcagga gatttggacg aggtcaacgc aaagccaact gttcagcttc
     1561 gtttccaaaa tcctcagcct aggattatca gcaatttgat atttacgagc aagatctttt
     1621 atgaaaatca gctttatatt gaaaatacgt ctaatgcatt tttagttgca ccaaattcga
     1681 attttcactt gaatcttgat ttagctggtg ataaagcaaa agccggcgat taccgcgcag
     1741 aaatcatagc aaaatcaggc gacagtaatg aatggcgatt tacacaaaac tttacgatca
     1801 aaaaagaaaa agcacaaaaa gtaaatgaaa attccgtttt tgcagtacaa gaacaatctt
     1861 tcccatggct ttatgcagga ttggttgctg cagttctagt gttatggttg attttgctgt
     1921 ttttgtgggt ccacaagaaa aagaaaaaag gagaaacaac atgatgaggt gatttcgttg
     1981 aaaacatcga tcttattggg agggattatt gcaagtttgc tgttcttcag ctggcaagag
     2041 ccagtccaag cagataccaa aagttcaggt acgattacat tttatgatct aagtccaatt
     2101 ccgcatccaa gtggttcagt caatggcgca tcaaaacagc agacacagct accgatttat
     2161 aaagaatcta atcaacatgg cgtattcccg gagacgaatg aacaaaagat ccgttttctt
     2221 tatttgatca ttggtataga attatggctt cttgcgtggt tgttgttatg gagaagaaag
     2281 gaaaaggagg atgaacatgt tgctacaaaa taaattttca ttttttcgct ccttcttttt
     2341 tacttcgctt tttgttttaa gtatatttat cttttcacct tcggcagaag ctgttggagc
     2401 aacgcctcct gccatttctt atgatccata cacgtatgaa aatatcgtac ctccaaatgg
     2461 tggacgtagt gcagtcaatg gcgggaagct tgtccaacta actggggcta accaattgcc
     2521 taaattgact gctacttatt tgaacgatgg ttcaaatgat ccttggaaag gtggcacggt
     2581 ccgttttcat tgggaaagcc atgtgaaact aacaaatgta cttgatttgg tgaatatcac
     2641 tgcacaagga tttgcatttg tggcgatcat caatttgccg gaacatgtat caagcagtga
     2701 tgtattaaaa gcaattgact ggaacaacgc ctacttgtat attgccggtg cccccatcaa
     2761 ggttactagc ggaagtttat tatcagcagg aagccatacc ttgcgttttg ggatggggtc
     2821 gtgggataca aatactctat tgacagatat tattgctatt attacgcgag gcgaattcaa
     2881 cgtggacgat atcccgcttc aatttgatgt tacagctaat gtcgcgaaga tgacagaaaa
     2941 cggagataaa tatgatacga gtccaaacaa aattttgacc aagggtaaat tacaaccttc
     3001 tatgtctaaa aaggccgttt tttctgttga tttttatgat tcgaataata ttatccaaga
     3061 tcgtatgttc aattcgattt tagctccagc tgcaggtaga ttttatccta aattaactgg
     3121 cggaaacttg aatccaggag catatgcatt ttctgcaagt gcagagataa atacgtggaa
     3181 tagttacatc tcaccaagtg attcaacagg aaaatataat acatttgctg ataccacaga
     3241 atacgtggat ggaaataacc agaaccttcc aggctctacc aatagtcgga cattgacgat
     3301 ggggctgact gaaggacgtt ttgatcagtt gccatttagt cgctttgatc gcgtagtcaa
     3361 ctattttaca ggaaaaaacg ttacacaagg agcaatactg actcatactc cagcaagcac
     3421 aagtggattg aatcagacag ccaatatcgt gtacagtggg aaagatgcgc aaggcggatt
     3481 gctttctcct gttgctttaa aggtattgga gcagtacaag ctagacggaa cggttttacc
     3541 aacaaactta acagccgata gtcagtgggg aaagctcctt tcttctgcat cgtaccaagt
     3601 cacggccaat tggtcagcaa ctgaactaaa aaagggttcg atccattaca ggctttattc
     3661 gaaaggaacc caaaaattag cgacaggatg gacagatcaa cttttccaaa cgatccaatc
     3721 aaataacggg ggtgtaaata cagctacttc tacactacct gcattggctt cagggcaata
     3781 ttattttgat tatcgcttgg tggacgatgt acttactaac atgtatccgt cttttgcgta
     3841 caaatggcag tctgaacaag ctggaatcac cactcttcct caaataacag tggctaattt
     3901 tccatctgtg agtgcagata gtcagctaaa aaaccttagc agacaacctg agacaggaga
     3961 tcccctgtct gctctatcag gagatacgat tcaagaaaat gtgacattca cgttaacaaa
     4021 atctggggat gcgataaccg acaaaaaaat cacgatctca cttcctgaaa atactactta
     4081 tatcaatggt tccttaaaat taaatggtac aactatcgca gataccggca ttcaacaagg
     4141 agtttctgtc ccagcagatc tattgagcaa aataggagat accattcatc ttacttacaa
     4201 ctatcaatta aatactgtag atacttcttt acaatccgtc agcatactga caaaggcagc
     4261 tgtactttcc agcaatatta cattagcaga tggtgctaag cttcctaacc cagttgtcca
     4321 aacatctgct aaaacaattc ttgtccccaa acaagaatta acattagtta atgtaccaga
     4381 tgattttaca tttggtaacg atctccccaa accgttgaag acaagttatt atgaatcaaa
     4441 aggcgatttt tcttttgatg tgcgggatac tcggcttcca agcacgtctc cttggcaact
     4501 gacaggtaca ttgacttctt tatttaagaa tgatcaaggt caagaattaa gcggaacaaa
     4561 attatacttc aatcattctg gatcaaagca attgattcag caaggtcaaa acacgttgat
     4621 ttatgagagt gatggaacag ctaaaggaga ggttctcgtt gactttcccg ataccgatgg
     4681 tttactctta gaggtaaata gcagtacgaa tgctcaacct ggcgcaacgt atcaaggcat
     4741 ggtcacatgg gaactgacag ctgggccaac cagctaagtg attagaattt gtatggatct
     4801 gtgataactg tcacagatcc tctttttcaa ggatgagaag gaaacttctg ctgttaaaat
     4861 cagaaatgct tgaaggagtg gacttggaac ttttcagttt gcttgaaaaa aatgaacaac
     4921 ggcaaatcaa acttttccaa cttttattag aggaaaaagg agaggtttcc gttaataacg
     4981 tacttacccg cttatcagtt gatcgggcta ccttgaaaga agatctgttt tatttacaag
     5041 ctaacttgga aaatatcaaa caattggaaa ttgttatcca agaagggaat attttattaa
     5101 tcagacatgg aaatatagca gcagtcgatg tttattatca ttgttacttg cgctattcta
     5161 caaaatatca gatacttctt tatctgttgg aaaatggctc atttgatcgg cagaaacttg
     5221 tcatggaact taatatcagt tcggctactt tgtctcgcag agtgaaggaa ttaaatgatt
     5281 ctttaaatga gtttcatctg aaaataaaaa gcgggcggct gaccggtcca gaaagtcaaa
     5341 ttcgttattt ttatttccaa ttattttggt ttggacgtcc ctatcttgaa aacaaaaaag
     5401 aatacagtga tttatcagga aacacttttt tagatctgct gcaaaaagag tttagttttg
     5461 ctattacaga agaaggacga ttgaaatttg aaatatggct ttccattatg aagaagcgaa
     5521 tgcgctgtac gaaaaaatcc aaaccagatt atagcaatct tcctgttgga ttgtttcaaa
     5581 cgacacaatt tttattggac ctccatacat ttttgacccg ttacttcttt caatatgcct
     5641 ttccttggaa tcaaaatgaa acgttggttt tttatctttt catgatcagt aactttacat
     5701 tagatacaca taactcgcat gtccaggagt ttttgataag cgaaaaatac aaagacgacg
     5761 tagtagctca attgaatcga acgtttaaac aatcgataga agaatatttc tctttttatg
     5821 tttttccaga agagatttcg caaaagattg cgttgacagt gatgcaaaat cacgctcatt
     5881 ttgcctattt tagaggatgg atgaatattt ttggccaaga aggattaaaa cagcggttaa
     5941 ctgaagtaga agataaacaa ttcctggttt tatgtgaaag attggtcaga caaacatttg
     6001 ctattgttga ttttactgaa gtagacgagg aaaatgcccg ctttgaatta tttgctcgct
     6061 atgcatctat tttacggacg ctgatcaagc agttagaatt acgtctgcaa attgcttatg
     6121 atcttcctta tgaaaggcta atggcggata tcgtgaaaga aatcatccag gaacaattgc
     6181 tgaatacgat caaatatgat ttagtcgaat acgagaaaga aaagcagtat gatatcattt
     6241 tgactagcca attgaaagag tacccgtcac agaagtccgc taaagttttt gtattcacta
     6301 gcaacgaata taattatgat ttcccctatt tgaaccaatt tttaaaagaa tgttatttag
     6361 aaaaattgaa tttaaggatg aataaaacat gaaaatcgtg atcattggtg cttcccatga
     6421 aggcatcaca gctgccctaa atctaagaaa acttcaaccg aaagcagaag ttttactgat
     6481 cgatgaagat cataaagatg gactaggcta tgtttcaaat ggaatcaacc tttatttaaa
     6541 aggaaagata cgtagtttag ctgaagttgc ccataacatg cggactcttc aagaaagtgg
     6601 ggcaaaactg atcaccgaat ggagagtaac tgaacttgat ccagacaaac atcagctcat
     6661 cctcgcatcc aaagaaggaa aaaacgagac cataacctat gataaattaa tcgtagcgac
     6721 aggttcctct cctgtcacct tgtataaaca aattgaagct gaaaatgtct acacctataa
     6781 aaatctagtg caatctaagc aagtacttgc cgctttaaaa gaagcaaaag aagtagtgat
     6841 cttcggtgct ggttacattg gattggaatt agcagatgct ttgagaaata aaggatacat
     6901 tattcatcta gttgattata tgccgaatgt tttatcaaga tatttcgata aggatatgat
     6961 caacagtttt caaaatcagc tgcaaactaa gcaaataaat ttttatccaa atgaattctt
     7021 gatcgattgg aaaaaatcag aagagaaagt agtatccgta caacttctgt ctcaaacaat
     7081 aaaggcagat atggtcattt tttctgccca aactcgtcct aatacgacat tgttaaaaga
     7141 aaaagtggct ttgtatgagg atgagactgt gatagtcaat gaatatctgc agacaagtga
     7201 tccggacatc tatgcgattg gagatatcgt cccagtcagt tttgacaaaa ataaacggca
     7261 tctcttttta cctttagtta ctcgagctgt acatatggca agagcagtag cgctaacttt
     7321 gagtggtcag ccaaccgctt acgacctcag acaaaagata acagcagcag tcattataga
     7381 ctacttttta ggaactgtag ggctgacaga agatgaagcg ccattcttgg aacaaaatac
     7441 cggttcgtgt tcaggagaat ttgatctatt tccacaatac gacgaagaaa acaaaacagt
     7501 aaatgcaaag ctgatctacc atccggatac attagaaata attggcggac agctgataag
     7561 ccaagaattc ttattatcag atttgaacct gcttgcggat atcgtgaaac acaaaactac
     7621 gattccacag ctagcagttg aggattttgg atttctgtct gaatacacct ctcgttttca
     7681 ctacctcaat gagttagctt ttaaagtact agctaagaga gcaaatagca atagagtaga
     7741 taaaagactg tgagaaatat cacggtcttt tattgtgtgg ggatataata aatattaatc
     7801 aatcgagaat aaaaaattca tataatgaaa tagcggaaga attttttgag cataatattc
     7861 gccaaaaatt tatcaagtga taaaattgtt gtataaaatg attatttcag gaggaggagt
     7921 taaatgtttt tagcattaaa tgaaattatg cattcaaagt tacgttatgc gttagttgca
     7981 ggggtgatgt ttttgatcgc ctacctggta ttttttttga ctgggttagc ttatggctta
     8041 gctcaagata atcgaacagc agtcgacaag tgggaggcag attcgattgt gctttcgaaa
     8101 gatgcaaatt caaatctagg gatgtccatg attactaaga agatagcaga agaagtcgaa
     8161 ggtgggaaag tggcgtatct tgcccaaaca cctggagtcg tgactagtaa agacagtaca
     8221 gaagaaggaa aaatcaatgt tagcttcttc ggtatcgata aaaatcaatt catcatgccc
     8281 aatcttgttg aaggaaaagc ttttgataac gatgatgagg cagtaggcga tattagtttg
     8341 aaagaagaat atggtctagc cataggagat acagttaagt tatctggtag tgacaagacg
     8401 tttaaactaa ctggctttac ggatcatgcc aaattcaatg tctcaccagt tctctataca
     8461 accatcaatg cttaccaaga aatccgcttc gaaaaagaag atacaagtga aaatgcacgg
     8521 attaacgcaa tagttgtcag aggtaaaatc agtaatttac ctgaagattt agaacagatc
     8581 aaaatttcta aattcatcaa tgaattacct ggatataatg cgcaagtatt gacttttgga
     8641 tttatgatcg gatttttgat cgttattgcg gctattgtga tcgggatttt catttatgta
     8701 ctgacgatgc aaaagattaa tatctttggt gtaatgaaag cacaagggat cacaggagga
     8761 tttattgcgc gttctgtagt ggcacaaaca ttcattttat catttgttgg tattcttctt
     8821 ggtctattag gaacagtggg aacatccctt gttctacctg atgcggttcc attccaaagc
     8881 aattggctgt tttttggcgt cattagcttg ttgatgttag tagtagctgt gttaggcgca
     8941 ctattttctg ttcggacaat cgtaaaaatc gatccgttga aggcaattgg ataagaagga
     9001 ggaagaacat gaaagcaata gaatttaaag aagtagaaaa aagtttccaa gatggcgacc
     9061 aagtagttaa agcattgaaa gaaacaacca tgagtatcga taaaggggaa tttgttgcaa
     9121 tcatcggtcc ttctggttca ggtaaaagta cttttttgac tttggcaggc ggattgcaga
     9181 cgcctagcag tggctctgta tttatcaatg atcaagaatt cagtaatcaa aaagaaagcg
     9241 aacgcgttaa actacgtttt aaagaaattg gctttatttt gcaagcttcc aatctggttc
     9301 cttttctgac agtaaaaaag cagttattat tagtagataa gattaaacat gaacatcgtc
     9361 aaaaagaagc aaacgaatta tttgagcagc ttggcgtgga taagttgatc aacaagtatc
     9421 cagaagaact atctggtgga gaacggcaaa gggtcgcaat cgctcgtgca ttgtacaatg
     9481 atccgtccat tattctagca gatgaaccaa ctgctagttt ggattcagaa aaggcacgag
     9541 aagtagtcga tatcttggca aaagaatcaa aagacaaaaa taaagcaacg atcatggtta
     9601 ctcacgatac acggctgatt gacaaatgcg atagaatatt tatgatggaa gatggtgtat
     9661 tgaaagaaaa agaataacca aaaagcaggt ggaaaaatgg tccatcgata caacaaagat
     9721 acacagcaaa aaattttgaa agaagcgact gacttgttta tgtccaaggg atatctcggc
     9781 acttcaacaa gagaaatcgc acaaaaagtt gggatcaccc agcccaatct ctatcattat
     9841 ttcggtgata aagaaaaact atatacggca gttttagaaa accacttaaa agatgttgga
     9901 aaagctttga gagaaatcgt tcaaacaagc gaaacgggat ttcaagtaac cttgacaaaa
     9961 atggcgcagt ttttgattga gacacatctg gtcgatttgt ttctgatgct tcacgatctt
    10021 gaaagcaatc tttcaaagga aacaagagat catcttttct ttctatggaa gaaaaattat
    10081 cgtgaacctt ttgaagaaat cttttcagca aaccaatctg tgctaagaaa tgggatttca
    10141 aaagaaatcg cagcaaggca ttttttctta gtgttagcac cttacatcac tcggtcgaaa
    10201 agacctgtgg aagaaccgct aaatgtggcg caattgatcg atttatattt gaatggtgta
    10261 ttaggagaag cgtaaagctg ttatataggg agaaaatagt taggtgaaga agcaagatat
    10321 gacgaagatc gttatatctt gcttctttat ataggtagtt tttcataaat acaaatttgt
    10381 tattctctca tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt
    10441 tttaatttaa taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta
    10501 gatgaatcac cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc
    10561 attttagcag taatgttatt ttctacggtt atatctttta cagccccttt tttgcttact
    10621 taagctgatt ttaagttttg gcccttagtc tggatctacg aggtgagagt caagaatgaa
    10681 aaaaataatt ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga
    10741 tgtttttggt caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac
    10801 aaagacaaag gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa
    10861 tgaccgtaca ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg
    10921 agagctggcg gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg
    10981 ctatactgga tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa
    11041 accggaagag ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac
    11101 tggggcatta agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat
    11161 aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga
    11221 tgaattagta cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt
    11281 tatcagttta cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata
    11341 ttattactat ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct
    11401 gcctctggat tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca
    11461 accttctatt ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt
    11521 aacagacagt tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt
    11581 tcagtaataa ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg
    11641 cttattatcg cagatgcaag cttttaaaca ccgtttaagg aagaggtcgt gagcctgccg
    11701 ttcaactctg agtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt
    11761 gtgacttgtg accgaggagt tggcatgaga acaccgttta agaaaaaggt tgtgaaatca
    11821 acgttttgtt ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
    11881 tgttgagcta ataccgagga tcagatgatt gaacaccgtt tattcggaac aagggactgt
    11941 gacatgactt ttgtcacagt tccattattt ttttagtagc ttcaaagctt tttctgtatt
    12001 ggcaaaatga agtttggcat atttttcaag cataggcatg ccgcctttct ccaatagttt
    12061 tgccgctact tggtcagatt tcgttccagc tcctgacgga agggtgattc cagcttcagc
    12121 tgatgctttg tctaactctt ccaaaaagct ggcacgactg atgatagaag cagcagcaac
    12181 agctaaatga tattgttctc ctttagtaac gaagtacagt ttttcttgta attgattttt
    12241 ttctaaacgc gcatattttt taaaatttgc ttccggcgta aactgatcga tcaaaatcgc
    12301 ttctggtttt tctggctcga ttttttttag cagcaaatgg atcgcttgat tgtgcaaagc
    12361 gactttcatc cgaacggcat tgtattttgg ttggatctca ttgtattttt ctggagataa
    12421 gacaagcagt ttatagggga tggttttttt taagatgtca gcaagctgga tgatttggct
    12481 atcttttaac tcttttgaat ctctaacacc aagtttacgt aattctgcaa gctgatcacg
    12541 tttcacataa gcagcacata ctgttagcgg accgaaatag ctgccatttc cgacctcatc
    12601 actacctaaa acggataatt gactgatatt ttttggcaaa gaagaggctg tttttgctgg
    12661 cttggcttgt ttatcctgtg cctcccccca tttatcagct tctattgctg cattcgtacc
    12721 ttgaaacatc acttttccgg atgtataagc ggtaatggtc gtcccgtctt tttttgcagc
    12781 aaagctagta taaggaatct gtttatttaa caaataagag cgatagtatg ctttcatttg
    12841 actaagttgg tcgtttgttg ctttgataat gacgttgctc ataaaattct cctcgttttt
    12901 atacataaaa ctataccgca actcacgact tttcgttttc taagagattg cgagacatag
    12961 cattttttta aagtttatca tataatagtt aagtatgtga aaaatatttg tggagaacgg
    13021 tgaaagaacc aacttcatgg tacactaaat aaaactttca tcaaatagga ggaaatgatt
    13081 cgtatggcgc acgaaaaaac acgctacaaa gcggtgattg ccaaccaaac atatactatt
    13141 atcggacggg aaaccaagca tcatatggat atcgtaacga agctgatcaa tgaacagtta
    13201 gcagaattga aacaattatc accacaaatg gataatgaac aagcagcaat cttgatggct
    13261 gtcaatgcgc tttcggatca attgaagaaa caagaaagaa tattggagct ggaagaagaa
    13321 acagcagaat taaagaaaaa aatgatcaaa tttacagagc ttgaaaatcg tgtgaaacgc
    13381 attgaagcaa tcgagaacga agctcgggaa gtattgaaag aaaatggtca agcagatcat
    13441 accattaaaa atcatgtgga agcacaacag attttaaacg agaaacgaaa aggacaaatt
    13501 aaacaaaaat cttctaatta agatcctttt atcaaaataa gaaaaattta aaaaagttag
    13561 aagagaaagg aacgtagcat gctgagtttg ctgattttat ttttattgct aattgcgttt
    13621 ttttctggag cacgtcgcgg gtttgctttg caaatcatat tcgcgattgg atatgtattg
    13681 tcatttattg ctgcccagca tttttacaaa ccattagcaa gtcatttgga attatacatt
    13741 ccatacccag ctgtcacccc aacatcaaag ttagcatttt ttgatcaggt atttgccttt
    13801 cacctagatg aagcttttta tgcaggaact gcttttctga ttattttgct aattggctgg
    13861 ctgcttaccc gatttgtggg ggtttttgtc catggattga cgtatgtgcc gatcttgaga
    13921 caggtagact ggattgcagg aggcatcctg tcactaatca tggcttacgt tactatattt
    13981 ttgattttgc agttacttgc ctttgttcca ttagatgtgg tccaaaatca attcggcgag
    14041 catagtttcg ctcgttttat cgttgagaga acgccatttc ttaccaacaa gatgtatgag
    14101 ctttgggtaa cgaatatttt gaattaagga aaatagtgct ggaaaatatt tcgttttttg
    14161 tacagagtag tttatttaag aaggctgcgt agcgtatgtc cggcacagct cttttttcat
    14221 agtgaaagat aaggtgataa aatgaataac cgaatccttg aaacattgga atttgaaaaa
    14281 gtcaaacaga tggtcagaca atttgtagtg actgcacaag gaaaagaaga actggcagaa
    14341 ttggtaccag tgagtgagaa acaaacgatc acaaactggc ttcaagaaac tgaggatgga
    14401 ttgaaagtgc aacgtctgcg aggcgggatc cctataccta aaattgaaaa tatccgtccc
    14461 catatgaaac ggattgagat cggagcagac ttgaatggag tggagcttgc acaagtttcc
    14521 agagtattgt ctacgacaag cgaattgaat cgtttcattg atgatctttc tgacagtgaa
    14581 atcgaatttg cacgtttgta tatgtgggca gatcagttag tcacgatccc tgttttgagc
    14641 cgccgtttaa aggaagcaat cgatgaagac ggacgcgtga ctgatgacgc ttctcctgag
    14701 ttaaagagca taagacagaa cattcggcga agtgaacaag ctgttcgtga acagttagat
    14761 gggatcgtcc gtgggaaaaa tgcaaagtat ttaagtgatg cgatcatcac catgcgaaat
    14821 gaccgctacg ttatcccagt caaacaagaa taccgcggtg tatttggcgg tgtagtccac
    14881 gatcaaagtg cttcaggtca gactttattt attgaaccaa aacaagtggt ggatttgaat
    14941 aatcgtttgc gtcaatacca aatcgctgaa cgaaatgaga ttcaacgtat tttaagtgaa
    15001 ctttctgctg aacttgttcc ccatcgtcaa gaaatcatcc acaatactta tgtgattggt
    15061 aaaatggatc tgatgaatgc aaaagcacga tttggtaaag aagtaaaagc catcgtgccg
    15121 ggaatcagtg aagacaatca tgtcgtcttg aaacaagcaa gacatccact gatcgatcag
    15181 gaaaaagtag tttctaatga catcacaatc ggaaaagact atcaagccat cgtcattaca
    15241 ggacctaaca caggtgggaa aacgatcacg ttgaagactt taggtctgtt acaactgatg
    15301 gggcaagcag gattaccgat tcctgcaggt gaagaaagtc aaatcggtat ttttgaggaa
    15361 gtatttgcgg atataggaga cgaacagtcg attgagcaaa gtctatcgac cttttcttct
    15421 catatgacga acactgtaga tattttatca aaagtcaatg aaaaaagtct ggtattattt
    15481 gacgagctcg gtgcaggaac agatccgcaa gaaggtgctg ctctagcaat cgcaatctta
    15541 gatgatcttg gtaaaaagtc tgcttatgtg atggcaacaa cgcattatcc tgaattgaaa
    15601 gtttatggat ataatcgggc aaatacgatt aatgccagca tggagtttga tgtggataca
    15661 ttaagtccaa cgtatcgttt gctgattggc gttcctggac gaagcaatgc gtttgaaatc
    15721 tctagccgat taggtcttga tacagaagtt attgatgaag cgaagcagtt gatgaatgat
    15781 gagagccaag atttaaacga aatgatcaca gatttagaga atcgccggaa aatggcagag
    15841 accgaatatc tggaaatgcg tcattttgtt tctgaggcac aagaacttca cgatgatttg
    15901 aaagaagctt acagctattt ctttgaagaa cgtgaaaaag aaatggaaaa agcaaagaaa
    15961 aaagcaaatg aagtcgtgtc agaggcggaa gaaaaagcag aaaaaatcat tgctgatatt
    16021 cgtaaaatgc aacagcagat tgggcaagga aatgtgaaag agcatcagtt gatcgatgca
    16081 aagacccaat tagcaaatct acatcaagaa gaaactttga agaaaaataa agtattgaag
    16141 aaggcgaaag aacaaaaaac gttgaaaccg ggagacgaag tgttggttac gacttacggc
    16201 caaagaggga cgcttttacg taaaaacggg aatcagtggc aagtagaaat cggtatatta
    16261 aaaatgaatg tgtccgaaga cgagctgacg cctgttgctc ctcaaaaaga gccgacacaa
    16321 cgagttatcc atgctgtacg atctgaatct agtagtcacg tgccgaatca attggacctt
    16381 cgaggaaaac gatacgaaga agcgctaagt gaggtagatc aatatttgga ttctgccatt
    16441 ctagctggtt atcctcaagt gactattgtc cacggaaaag gaacaggcgc acttcgcaag
    16501 ggaattactg attatcttaa aaaccatcgg agcgtcaaaa gctttgagtt tgcaccggca
    16561 aaccaaggcg gaaatggtgc gacaattgtt aaatttaagt aaagcttact aaaggtaagc
    16621 agatggttcg ctatccaagt atagaaatgc tatactagtc atagatttta aaaatggagg
    16681 tctttgatat gtcacaagta attacagata agacatttaa tgaagaaaca gataaaggac
    16741 ttgtattgat tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa gcaccgattt
    16801 tggatcagtt ggaacaagaa tatgatgaag aagaattcag aattgctaaa atggatgtgg
    16861 atgaaaatcc agaaactcct caacaattcg gtatcatgag cattccaaca ttaatgttga
    16921 aaaaagatgg tcaagtagta gaaaaagctg ttggtgttca ttcaaaagaa caactacgtc
    16981 aaatgatcga tcaatattta taaaaactta cagcaaaaat aagctgaggg tgggactgaa
    17041 tccagttccg tcctcggttt ttttgcggtt gagttaaggt tattcaaatt aatatttttt
    17101 gagtataatt acgttgtcag gctggattgt ttttttgaca gacatgctat aataacttta
    17161 attgaatatg aaggggagta ccagatgaac gaacgaatca aaaacaaatt agctttactt
    17221 cctgatcagc ccggctgtta cttgatgaaa gataaaaatg gaacgatcat ttatgtcggc
    17281 aaagccaaaa tattaaaaaa tcgtgtccgc tcatatttta ctggtagcca taatacgaaa
    17341 acggaacggc ttgttagtga aatcgaagac tttgaataca tcgttacaga atcgaatatc
    17401 gaagcattgc tcttagagat caatctgata aagaaaaatg atcctaaata caacattatg
    17461 ttaaaggatg ataaaaccta tcctttcctt aagataacga atgaaaaata tccccgtttg
    17521 gtgattactc gtaaggtact aaaagacaaa gcactgtatt ttggaccata tcccgatgtc
    17581 ggtgcggcga atgagacaaa gaagatcctc gatcgattat ttcctctgag aaaatgcaaa
    17641 cctagtcaga cgaaggagcc ttgtctttac tatcatttgg gacaatgcct gtgtccttat
    17701 tatttcgacg tagatccgaa agtctatacg aaaatcgttg atgaagtgaa aaacttttta
    17761 aacggaggac acgaaaaaat cgagtcagag atccatcaga aaatggaaaa agctgctgaa
    17821 aacatggagt ttgaaaaagc tgcagaatac cgagaccaga tccgtgccat tgagacaatc
    17881 atgactcgcc aaaaaatgac aaatactgat ttactggatc gagatgtatt tggttatgcg
    17941 attgataaag gatggatgtg tgtccaagtg tttttcgtaa gacaaggaaa gctaattgaa
    18001 cgagatgttt caatgtttcc tttctataac gaagcagaag aagatttctt gacttacctc
    18061 ggtcagtttt atcaggaaaa tgagcatttc attcctaaag aagtcttgat tcctgatacg
    18121 atcgacaagc ccagtgtaga agctttgtta gctacgaaag tgctgcaacc aaaacgagga
    18181 gaaaagaaaa aattagttga attggcgagt aagaatgcct cagttgcttt gaatgaacgg
    18241 tttgatctga ttgccagaaa acaggaacgg acgatcggag cagttgaacg tttaggaaac
    18301 gcgatgaata tcccgacccc aatacgtatc gagtcttttg ataactctaa tatcatgggg
    18361 acgaatcctg tggctgcgat ggtcgtattc attgatggaa aaccggcaag aaaagaatat
    18421 cggaaatata aaataaaaac agtcaacgga ccggatgatt atgcatcaat gagagaagtc
    18481 atctatcgca gatattcgcg agtgattcgc gaagggttgc ctttacctga tttgatcttg
    18541 atcgatggag gaaaaggaca agtagatgtg gcaaaagatg tcttagaaaa tcaattagga
    18601 atcgatattc ctattgctgg catggtaaaa aacgataaac ataaaacaaa tgagttgcta
    18661 ttcggtacag atttggctgt agtaccgctt gagcgaaatt caccagagtt tttcttactc
    18721 cagcgaatcc aagatgaagt ccatcgattc gcaatcactt tccatcggca gctacgcagt
    18781 aaaaacagtt ttgcttcccg attagatgaa attgaagggt taggaccaaa acgaaaaaaa
    18841 atgctgctta aagagttcaa atcgttgaaa aatatcacag cagccacgac agaagaatta
    18901 caagaaatcg gactgccgaa aaatgtcgca caaaacgtat ttgataaatt acatcaggaa
    18961 tgaggaaagg gcactttaca aagaaagtaa agtgtcctat cattttatgt acaacaaaaa
    19021 gagcgtttac gttttgttgg taaataataa atcgcttacg tctggtgtct aaggatatat
    19081 gtgatttctt gaagaaggag tgaagaaatg ttagaagtca aggatcttgt taaaactttt
    19141 gggaactaca cagctgtcga tcatgtctct ttccaaatcc ccgatggaaa aatcatgggg
    19201 ctaattggcc aaaacggggc tgggaagaca acgacttttc gtttgatctt ggattttttg
    19261 acacaagacc aaggagaagt gttatggaat ggccatcatc ttggggagaa agattatgat
    19321 gtcatcggtt atcttccgga ggaacgggga ctttatccga aagtaacgat tcaagaccaa
    19381 ctgctttatt ttgcagaact tagagggaaa tcaagaaaag agattgaacc aaaaatcgac
    19441 ttttggatgg aaaaatttca ggtaaaaggg aaaaagacgg ataaagtaaa atctttgtct
    19501 aaaggaaatc agcaaaaagt ccagctgatc gccacgttaa tccatgaacc taaattgatc
    19561 attttggatg agccattcag cgggttagat ccggtaaatg ctgaattgct aaaagatgga
    19621 atattggaat tgaaaaaaca tggttcatgt gtcatttttt ctagccacaa tatggataat
    19681 gtagaaaaaa tctgcgatca tttgatcatg ttgcgaaacg gaaaaatggt tttgaatgga
    19741 aaagtacatg agattcgtga atcatttggc cgtacgaagt tattcttgga atctggttta
    19801 agccaacagg aagtagaaga aatcgaaggc gtgaaaaaag tgatccttca tgaagacaat
    19861 acgttagaga ttaccttaga agatcctgaa gctgggaaag aaatctttac tcgtgcgact
    19921 cagttcggct acattcctat gtttaaccag caaccgccaa ctttggaaga gattttcaaa
    19981 ttgaaagcag gtgaaatcga tgcgtaagtt ttggattatt accaaagatg tctatttaaa
    20041 aaatgttaag tcgatttctt tcttgatcat gatattagtc ccttttatca tgctgggtat
    20101 catttatgta gcaggaaact ttgctcaaca aaatagtgat gtcaataaaa tcggcgtatt
    20161 ggctgataat gagcaaatca gtcagcaaat gagccaagtc aaaacagatg attttgagtt
    20221 caaagcagtt gattctgaag aaaaagcaca aaaagagctt tcggaagaaa aaatcgatgc
    20281 gtatttagta gtctcaactg agaatgataa gataaatggg atgctttata gcgaaaattc
    20341 attaggacaa agtacacaac tactgataca acaacaactg actggcttgc aatcgatgct
    20401 tcgagcgagt caattaggca tttcaccaga agaagtagct agcttgagcc aacaagcaag
    20461 tttgactcga caaaaagtca attttgattc aaaaggaaaa atgacagtcg gagaagataa
    20521 ctcgacagtc caatacgtcg taagttatgt agcaacgatt gtcttgttca ttattatttt
    20581 gacgtatgcg cagatcattg cacaagagat cgcttctgaa aaaggcacgc ggatcatgga
    20641 agtgatcctg tccagtacga ctgcacaaaa gcatttttac ggaaaattaa caggtgtttt
    20701 acttgttgca ttaacgcaaa tggcattata cggtattatt tttggtatag gatacagtca
    20761 attcaaagat atggaaatgg tcaaaaatat attagacggt atctcattgg ataacttgat
    20821 tggaccattc ttgtggtatt ctcttctatt catgatcttt ggcattttga ttttttctgt
    20881 tttagcagct ttatgtggct ctttggtcaa caaagcagaa gatacagcaa aagcaatttt
    20941 gccagtgact tatctatctc taggcggata catgcttgga ttgatactag gagcttcaga
    21001 tccaaacaat atcgttattc ggatcacttc gtatattcca ttcttatctt catatattat
    21061 gccgattcgc ttagcaaatg agacagtcgg tatgggtgga gcattgattt ccttgttggt
    21121 acttgtagcc gtaacattct tattgatgat cttgtctgca aacatgtaca aatcgaatgt
    21181 actcgtttat agcgaaggcg gattatggag ttcattgaaa caatcgattt caattatgag
    21241 gaatgaacga aaaaaagcat aaaacaatcc taaaatacag aaggaagctg gacatctatt
    21301 gttcccagct tctttttgta tagacctatt ttatttattt tactatattg gatatatatt
    21361 cattgaaaat agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt
    21421 taatggaccg ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca
    21481 cggaaatcat caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga
    21541 gtgatataca tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc
    21601 ttaaagaaaa gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat
    21661 tcactatttt tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag
    21721 ataaatcgca gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata
    21781 cccggtcaaa agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct
    21841 tgtatatcga tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac
    21901 ttgttttgat gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat
    21961 ctgtcatcga tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca
    22021 aagtgatgga tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata
    22081 ttttgtggat tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg
    22141 cagcacgcta taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat
    22201 tgttttcttt tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta
    22261 aaaatctatc cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc
    22321 ttcaattcaa atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc
    22381 gtaaattgct ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct
    22441 atgagttgaa aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaattcttgg
    22501 aagaggaaca aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc
    22561 aaaaacatat gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg
    22621 tgctgtttca tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag
    22681 accaatctta tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg
    22741 caaaagatct gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg
    22801 ggccattttc gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca
    22861 cagagcctca tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt
    22921 ggttcagtga aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta
    22981 atgggcacac gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag
    23041 tatttgtcat tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt
    23101 attcactatt atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta
    23161 ttgaacaaca atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc
    23221 aactaccacg caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta
    23281 cccagctcaa aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat
    23341 tgttccatag actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac
    23401 ggtgttcttc tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg
    23461 ttttttgaaa ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat
    23521 aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa
    23581 gccattttca caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc
    23641 agaaagtcta ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta
    23701 cacggtgggt aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc
    23761 tttgaaccgc ttcaacgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa
    23821 gatctttgac tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc
    23881 ttaacaaact gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct
    23941 gttgttcatg ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt
    24001 ccaaaacgac attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt
    24061 tcaatgcttc caagatcagt gcctgttcaa attggtctcg ttgaatattt gttccgttag
    24121 ctttggatga ggatcttcca tgtaaagttg tggactgaca tcttgaccac ctgcaagaat
    24181 aagtttgtcg atttgtccaa tcagttgagg agctgaatct ggagacatga ctggcagaat
    24241 aagaggcaat ccttgagcat ctaaaactgc atccacgaat ccttgcggtg tatagctcac
    24301 ttgatttcct tggaaagtat ctgttgctcg aatcagttga tttccggcaa tgccgatgat
    24361 tggtttcatt tgtattcccc ctaaagtaga cttattgtaa caaggattta aaaaaaatta
    24421 aactatgtaa gacttgcccc tatacttatc tgttcttgct gtgttactat ctgtaaagag
    24481 aaatttcgtg tgaaattcat gacgatagtt gaaaatattg cttaatttgt tataataaaa
    24541 agtaagcaga aataaaaagg ttgggcgtaa gcttcaagga tctagttctt caaggggtga
    24601 gaaggacatt ttattgaagg ggcctgccta tactaagtta tctttagagg tacatacttt
    24661 caatgaaaaa agaaagcatg tacctctttt ttaaatcgaa aggaagtgaa gcaagtgtta
    24721 gaagctttgg aacaaatccg aaaagcagaa gaagaaaatg aaaagcgtgc tcaaacactg
    24781 cggcagcagc tgaagatcta tgcaacagaa aaagagcagg aattggaaac gatccaaaca
    24841 aactatcgac aacaactaaa acagttggtg gaagaaaaag aacaatttga aatacaagaa
    24901 ttagaaaaag aaaaaatgaa attgaaagca gaagcagaca aggtgcaagc aactttgaaa
    24961 gatcaatatc aaaagcatca gagtcaagcg atcggtgcga tcattgaaag ggtgaaagaa
    25021 acttatggcc gtcactaaga tggaaaaagt gaccctcatt tcagataaaa gaaatcagga
    25081 gaggatttta caagcagtac aaggaatcca aaacgttgaa atccgggatc tgtatcaaaa
    25141 tagaacaaac aaccagtggg tggagaagta ttttccagat accacgatta ttgataaaga
    25201 agcaaaatta agcgctttag gtaatcggtt gaaagacatc caagaagcta tccaattcat
    25261 acaacaccac ggcgatagcc gtcaaaagaa actccatttg aaacgtcaag aactttcctt
    25321 acaagatttg gaagccaatt attccgaaga aaatttcata aataaattga aagaagtcct
    25381 tgatttaaaa gaaaagtggg aacaactaac tgaagaacgt gatcgtttag aagaagagga
    25441 agaatggctt cttcattggc aacagctgga tattgctcca agtatgtatg caagtaagac
    25501 gaccattttt gagatgggga ctgtgagtgc agcaaatttt gaaagtttca aggaagaact
    25561 gagtaagctt gatgacgttt atatggaaga aatagattat acgccaaaac aagtttatct
    25621 ttcgtatgtt gctttaaaaa aatcagttgc tgttatagaa gaaattgctg ggaaatacgg
    25681 gttcaataaa gaaacgtatc cttatgaaca aaatcctaaa gaaaaactgc aagagaccaa
    25741 gcagcaatta tccattgttc acgagcagca aaagaagata acgacagcgt taggtcagtg
    25801 cagtggctat atccaagaat ttgaatgggt agaagaagtc acacttgccg ttgcagaacg
    25861 agaaaaaata aaagaacggt ttatccatgc gacttatctg atcgttttgc aaggttgggt
    25921 agatgcagaa gaaaaacaga atttgctgca tgtgttaaac gaaaccgtat cagaagaaga
    25981 tatatacgtc agtttcgaaa caccaaactc agaagagatt cagcaggaag tccctactaa
    26041 attgaaaaac catccgcttg tcgaaccttt tgaattgctg actgaaatgt acagtctgcc
    26101 aaaatatgaa gaagtagatc caacaccttg gatgacacca ttttatcttg tcttcttcgg
    26161 gatgatggtc gcagatgttg gttatggttt gctgatgctc attgggacaa tactagctca
    26221 aaaactactt gttctaccac gcgggatgaa acgtttcgta aaattctttg agattctctc
    26281 gataccatcg atcatctggg gattgatcta cagttcattt ttcggacagt cattaccaaa
    26341 agaactgttt ggcatccgct tgcctttccc aatcctatct acgacggatg acgtcaatac
    26401 gattttgatt ttatccgtga ttttcggtct gatacagatt ttggttggat tatttgtggc
    26461 agcaaaggaa aatatcagga gaaaagatta cttgagtgct gtcagtgatg gatttgcctg
    26521 gcaagggatc ctaattggga tcgttattgc gttggttggt gccatgttga taaaaaatac
    26581 agcatttgtt taccttggcg ctgggctatc gatcattgct gccttatgta tcttgatcgt
    26641 tccgattatc caaacgccgt ctaaagtcaa aggtgctgcc aaaggtgcgt ataatcttta
    26701 cggactgacc ggctatatcg gtgatttagt cagttataca cgtttgatgg cattgggtat
    26761 ttcaggcgga agtattggag cggcattcaa tatgctagtt gctttcatgc cgccagctgc
    26821 tcgattcagt gtagggatcc ttttgatcat cgctttacac gcactgaata tgtttttgac
    26881 actgctaagt gcctatgtcc atggcgcacg attgcagtat gtcgaatttt ttgggaagtt
    26941 ttatacagga ggcggacgtg cctttgatcc gctgaaaacg gcggaaaaat acgtcaacat
    27001 caatcacaag aaaaaaaaca ataaataatt ggaggatttt tatataatga tggattactt
    27061 aattagtcaa aatggtggaa tggtatttgc ggtattagcg atggcaacag cgacgatttt
    27121 ttcagggatc ggttcagcta aaggtgttgg aatgacaggt gaggcagcag cagcattgac
    27181 aacaagtcaa cccgaaaaat tcgggcaggc tctgattctg caattgcttc caggcacgca
    27241 aggtttgtat ggattcgtta ttgccttttt gatttttatc aacttaggaa atgacatgtc
    27301 agttgtacaa ggactgaact ttctaggtgc ttctctgccg attgctttta caggcttgtt
    27361 ttcaggtatt gcccaaggaa aagtcgcagc ggcaggtatt caaattttag cgaaaaaacc
    27421 tgaacatgct acaaaaggaa tcatttttgc tgcgatggtt gaaacatacg cgattttagg
    27481 tttcgttatt tccttcctat tagtgttgaa tgcctaagca taaaggagga aaagcagatg
    27541 aacgccattg aaaaaatcat ctctcagatg aacgaagcag cagagcagga aagagcggcg
    27601 ttagaacaag aagagcgaat gaagatcgat caaaactttg aacaaaaacg tacgcaagtt
    27661 gaaacagaac atcaaaaaca aaaagaaaaa caaatcgaat tactcgaaaa aaaataccgt
    27721 cagctaagga atcgccagca agtagaagta cgacaagaaa atttgaatgc gaagcaggaa
    27781 tttttaagac gattgtttgc agatgcggta actgaaatgg aaaattggga tgaatctgaa
    27841 caaatccagt ttatcaaaaa tgcattgtat tcattacctt tgacaggaaa agtagcattc
    27901 attgctggag aaaaatcagc agcctatctt tctcagacgt tgttggatga atggaacaat
    27961 gaacttccct ttatgatggt tttaagtgat gaaactgttg ctgatcaagc gggttttctg
    28021 ataaacgatc aaggagttca gtataatttt cttttcagca gccttgtaca agatatccaa
    28081 ggaacgatga gttttgagat tgccaatcaa ttattcgaat aaggagggat cagtgtatgg
    28141 aataccacga actaaatccc ttgattcgcg gaagagagct tgaacttttg tccaatgaga
    28201 catttgaacg gatgattcaa acaaattctg tcgaagcact tggtgaaata ttgaaatcca
    28261 cgatttacag tccatatatt tatgacggat atgaatatga cttcgaacag aatcttttaa
    28321 aggagcagag ccgtctattt cgctggttaa aggaatcagc accggagcct gaaatcgttt
    28381 ggatctatac gatgcgttat actttccata atctgaaggt tttgacaaaa gctgagatga
    28441 caaatcaaaa tctggaccat ttgtatatcg acgatggatt ttattcatta gaaaccttga
    28501 aggatgccat tcatacgcaa gtttcaaatg aacttcctga aagcattatg gacagtatac
    28561 gagaagtacg tgattatttt gaagagtcta ccattcttca gggaattgac gtgatttatg
    28621 atcgacagtt tttgacagag cagcgacggc ttgccgataa gctaggatat caagaattgc
    28681 tgacagaagt cattgctttt attgacttga ccaatatcac aacgatggct cgaggaatat
    28741 tgcagaaaag aacatatggg ttcatgacga cggtactttc cagctcggga agtatcgaaa
    28801 aagaagtatt tttgaacttt gtagataaag atatggaaga ttacacgaat tttctattag
    28861 agacagatta tgctgatttt ctgcgccctg tcatccgtga gggaaatatt gatctcgtaa
    28921 agcttgaaca gttgaaagat gattatctaa gttcattgta tcaagaagca caaacccagg
    28981 ctttcggacc actgccacta ctagcctttt tgaacgcaaa agaggtagaa agcaaaaacc
    29041 ttcgtttact ggttatcggc aaaagaagcc atttcgaatc agaaacaatc agaaagcggg
    29101 tgagacaagt ctatgacgca taagatcggt gtagttggcg acaaagattc tgttttgcca
    29161 ttcaaattgt ttggctttga tgttcgttat ggtacaacca agcaaaccgt tcgtcaggca
    29221 attgaagaaa tggcaaagaa tgagtatggc gtgatttatg tcacagagca atgtgcagca
    29281 ttgagcccag aaacgatcga acgttacaag gaacaaatga tacctgctat cgtattgatt
    29341 cccaatcatc aaggatcatt agggataggg ctggaagaaa ttcaaaaaaa cgtagaaaaa
    29401 gcagtaggtc aaaatatctt atagtatgaa aaggagatag aaattttgca aattggaaaa
    29461 atcataaaag tctccggacc tcttgtaatg gctgagaaca tgtctgatgc cagtatccaa
    29521 gacatgtgtc tagtgggaga tctaggagtt atcggagaaa ttatcgagat gcgtggcgat
    29581 gtggcgtcta ttcaagtata tgaagagact tctggaattg gtccaggcga accggttcgc
    29641 tctactggtg aagctttatc tgttgaatta ggaccaggga tcatttcaca aatgtttgac
    29701 ggaatccaac ggccattaga tacctttatg gaaatcacac aaagtaattt cttagggcgc
    29761 ggagttcaat tgcccgcatt ggaccatgag aaaaaatggt ggttcgaacc aacagtagaa
    29821 gccggagaaa cggtgagtgc tggagatgtt atcgggatcg tagaagaaac aaaagttata
    29881 aaacataaaa tcatggtgcc aaatgggata aaaggaacga tcaaaacaat cgaaaaaggt
    29941 tcattcacta ttgatgaaac agtatgtgtc attgaaaccg aaaatggtga caaaaatttg
    30001 acgatgcttc aaaaatggcc agtaagacgt agtcggccaa tcaaagaaaa attaaacccg
    30061 gatgcaccca tgatcactgg acagcgagtg attgatacat tcttcccagt gacaaaagga
    30121 ggagcagcag ctgtacctgg tccttttggt gcagggaaaa cagtcgttca gcatcaaatt
    30181 gcaaaatggg ccgatgtgga catggttgtc tatgtgggat gtggcgagcg tggaaatgag
    30241 atgacggatg ttttaaatga attccctgaa ttgattgacc ctaatacagg agaatcgttg
    30301 atggaacgta cggtattgat tgctaataca tcaaacatgc cagtagcagc tcgagaagct
    30361 tctatctata cgggaatcac aattgcggaa tatttccgtg acatgggtta tgacgttgct
    30421 atcatggcag actccacttc acgatgggca gaagcacttc gtgagatgag cggacgtttg
    30481 gaagaaatgc ctggtgatga aggttatcca gcttatcttg gttcacggct tgcggaatac
    30541 tatgaacgat ctggaagagt cattgcatta ggatcagaag gtcgcgaagg aagtataacc
    30601 gcaatcagtg ctgtatcccc gtctggaggg gatatttcgg aaccagtcac acaaaataca
    30661 ttgcgggtcg taaaagtatt ctggggtctt gattccagtt tagcccaaaa aagacatttt
    30721 ccttcgatcg attggataca aagctattct ctttattcaa cagaagtagg gaagtatatg
    30781 gatcatatcc ttcaagctga ctgggcatcc atggtcaccg agggcatgcg tattttgcag
    30841 gaagaacagc agctgaatga aatcgtgcgt ttggtaggga ttgattccct ttcagataat
    30901 gaccgtctga cattagaagt ggcaaaatcc attcgtgaag attatttgca gcaaaatgct
    30961 tttgatgatg tcgatacatt cacttcaaga gagaaacaat tcaaaatgtt gaagatgatc
    31021 ttgacctttg gtgaagaagg acgccgtgcg ttgtcgttag gtgcttattt aagtgagatc
    31081 atggacggta ccgtatcgat tcgtgaaagg atcggacgaa gcaaatatat cccggaaaca
    31141 gaattagaaa aactagatca aattattggt gaaatcaagc aaacgatgca aacgatcgtt
    31201 tcagaaggag gcatgagcaa tgattaaaga atatcgtacg atcggtgaag tcgtcggtcc
    31261 attgatggcg gttgaaaaag ttgctggtgt caaatatgaa gaattaatcg aagtccgtat
    31321 gcaaaatggc gagattcgtc gtggacaagt attggaagtc caagaagata aagcaatggt
    31381 ccaaatattc gaaggaacaa gtggtatcaa tttacgtgac tcttctgtac gatttttagg
    31441 ccatccttta gaactaggtg tatcggaaga catgatcggt cgagtattcg atggtttggg
    31501 acgaccgaaa gataacggac cagagatcct gcctgaaaag catttggata ttaacggaga
    31561 agtaatcaat ccagtagctc gggattatcc agatgagttt atccaaacag gtatctctgc
    31621 aatcgatcat ttgaatacat tagttcgtgg gcaaaaatta ccagtatttt ctggctctgg
    31681 tcttcctcat aaagaattag ctgctcagat cgcgcgacaa gcaacggtac tcgattcatc
    31741 agatgatttc gccgtagtct ttgctgctat tggaatcact tttgaagaag ctgaattttt
    31801 catggaagat tttcgtcaaa cgggcgcaat cgaccgttct gtcatgttta tgaatttagc
    31861 aaacgaccct gcaatcgaac gtatcgctac tcctcgtatg gctttgactg ctgcagaata
    31921 tcttgcttat gaaaagggaa tgcatgtttt ggttatcatg acagacatga ccaactatgc
    31981 agaggcattg cgagagattt ctgcagcacg gcgagaagtt ccaggaagaa gaggatatcc
    32041 tgggtatctt tacacgaact tagctacttt attcgaacga gcaggaagaa tccgcggact
    32101 aaaaggatcg gttactcaaa ttccgattct aacaatgcca gaagacgata aaactcatcc
    32161 aatccctgac ttgactggtt atattacaga aggacagatc atcttgacta gagagcttta
    32221 caagagtggg attcagccac caattgatgt actcccgtct ctttcgcggt taaaagataa
    32281 gggaactgga cccggaaaga caagagaaga ccatgcagct acgatgaatc agctttttgc
    32341 agcctatgca caaggaaaac aggcaaaaga attagccgta gttttaggtg aatctgcttt
    32401 atctgatgta gacaagatct atgcgaagtt tgctgagcgg tttgaaaaag aatatgtcaa
    32461 tcaaggattc tacacgaacc gttcgattac tgaaacactt gatctagggt gggaactgct
    32521 atcgatgttg ccaagaaccg aattaaaacg aatcaaagac gacatgctgg acaaatatct
    32581 gccagaaggg aagtgagttc tgatggcacg attgaatgtg aatccgaccc gcatggaatt
    32641 gactcgattg aaaaaacagt tgacaactgc cacaagaggg cataaattat taaaagataa
    32701 gcaagatgaa ctgatgcgtc aattcatcct gttgattcga aagaacaacc agctgcgtca
    32761 agaaatggaa gagtctatga cagaagcaat gtctgatttt gtattggcaa atgcttcgat
    32821 cacggaacct ttcatcgaag aattatttgt tttgccggcg gaaaacgttg atttgtctat
    32881 cgtagacaaa aatatcatga gtgtaaaagt acctgtgatg aattttgaat atgatgaaca
    32941 gctgacagac acacctttgg aatacgggta tttgaattcc agtgccgaac tggatcggtc
    33001 aatcgatcgg tttactaccc tgcttccaaa acttttggaa ctgacagaaa tcgaaaaaac
    33061 ttgtcaactg atggcgagtg aaatcgaaaa gacacgtcgg cgagtcaatg cattagaata
    33121 tatgacgatc cctcaattag aagaaacgat ctattatatt cgtatgaagc tggaagaaaa
    33181 cgagcgcgca gaagtaacaa ggttgatcaa agtaaaaaat atgggtacca ctgactaagt
    33241 ggtatctttt tttaaaagag gaaaacgatg attaaacaaa gcaaacaaat aaagaaacgt
    33301 ttgccggctg ttcagcttct cgcattagga ttttttctcc tgattttagt tggcggcggc
    33361 ctacttaccc taccattttt tagtaatagt gggcatggga caaattttat cgatgcgctt
    33421 ttcactgcaa cttctgctgt ctgtgtaacg ggattgacaa cattgaatac agcagagcat
    33481 tggaacagtg ctggtcaatt tttgatcatg cttttgattg agatcggcgg tcttggtttt
    33541 atgatggttc cgattctatg ctttgcattg ataaagaaga aagtcagtct cagcacacgt
    33601 attatattaa aagaagcgct gaatctagaa gaagtatcag gtgtgatgaa gctcatgctt
    33661 tacatcctaa aattggcctt tgtgatccaa ttgattggta cggttgcttt atcttttgta
    33721 tttgtgcctg aatttggctg gttgaaaggt atctggtaca gtttgttcca tgcaatctct
    33781 agtttttgta atgcagggtt tgatttgtta ggagacagtt tagccaatca ccagcaaaat
    33841 gtttatttga tcatggtggt atctgctttg atcatttctg gtgggttagg cttcatcgta
    33901 tggcgtgatt tactggaata tcatcagaaa aagaagatga cgattcattc aaaaatcgca
    33961 ttaaccgtta caggtaccct tttattaggc ggattcgttg tgttcttttt cacagagcgc
    34021 aatggggcaa cgctagtgga agggaatatg tttcaacgat tggcaaacac cttttttatg
    34081 agtgtgacac ctagaacggc tggatattat tcagttgatt acctccatat gagccatgca
    34141 ggtctgattt taacgatgtt tttgatgtac atcggcggaa catctgggtc gacggccggc
    34201 ggattgaaaa caactacgtt aggtgtgttg ctgatccaga tgcgttcgat gttgaaagga
    34261 cgtacgagag cggaagcatt tggccgtacc atccgacaag gcgcagtgtt gcgggcactt
    34321 actttatttt ttgttacgtt gacgttgtgt gtagtcgcca tcatgatttt atcggtgact
    34381 gaaacgatac ctaaaacttc tggcatcgaa tatattgctt ttgaggtctt ctctgcgttt
    34441 ggtacagtag gtcttacgat gggattgacg ccagacttga ctgcaatagg gaaattgatc
    34501 attatagcgc ttatgtacat tggacgagtt ggtgtattga ctgtggtctt ctctctgatg
    34561 acaaaagcac aaagaacaca atcaaaatac aaatatccag aagaaagtgt catgattgga
    34621 taatttcatc ttctgacaga aacctagtga tttagtaaaa taagaaaata aaataatttt
    34681 tcttgcttct tggatacttt aagtgcaaaa tgttcgttta ttttttgagg cactacccgt
    34741 tgttgaacct cgggtagtgc ctctttttta ttgaaaggaa tcaataagat ttgattcctt
    34801 tatttatcaa taggttataa ttcatatttt tttatttttt cttttacgat acttagtcca
    34861 gaagctaaaa tttcaaggtt attagaggat agggaaattc gaacgaatgc atctggttgc
    34921 gcacgtgtag taaagcgtct ggaatgataa agtcggatac cgttagcaag aaagtcattc
    34981 tcaattatct tagggtcaat ctcaggatca actggaagaa ttcgatagta agggacacga
    35041 ttcgttggtt tttctacttt gaaaagagaa tcaaaaagct gattggctct ttttgtaaga
    35101 cttaatttag tttctaagat cctatttgct tcatttgaat ggaggatttg agtgatgact
    35161 tccacatcta atccagaagt tttcacattt atattaaaaa ttgcttgttc tatcttgctt
    35221 tggacatgta ctggaactac aagataagca actcgcaatc cagaacaaat aaattttgtc
    35281 attccagcta agtagattgt ttggttaggt aataaatttt ggaaaggagg aatgatcgta
    35341 tgttgatagt aagttgttaa aaatgaatgg atatcatctt caataaccca tagaccttct
    35401 ttttcaatca cttcggctaa ttgctctcgt cttttgtgag agatttgaaa ccctatagga
    35461 ttattacaag aaggcataag aaagacacca tgaatcttct tttttctaca ttcctgaatc
    35521 aatatatcag gtcgcattcc ttgctcgtca aaatcaattg gaacgatctc taaatgatat
    35581 aactgagcca attcaatgaa attagcgtat gtatatcggt ctgttgctat tctatcacct
    35641 ggagagaaaa gtgcagaaag tgtgatagcc aatccatttt gaacaccgga aacaatagat
    35701 agagattcta aggacggaat gactccttga gtttttaacc aatttgctgc agtagtcaat
    35761 tgaaaatttg tgcctttggg atcttggtaa ttaagcaaac caacaagatt tgggttatta
    35821 ctagttgatt gaataaacgg gacaacgaat ttattacatt cttcaaaaga actaaccaga
    35881 ccaaaatcaa tgatatgttc ggttacttca ttggtagaga tggtgatgga ctcaaagaca
    35941 ttgggagaaa taaatgtgcc acttccaata ttcgtataca gcaaaccttt ctcaattcca
    36001 tatttataag ccttgccaac ggtagtaaaa tttaaatcta aataatcagc tagctctctt
    36061 tgggagggta actgagtgtt tttctgtaat ttattcttta aaatatcttg ttctaattgt
    36121 tgaatcaacg atcgataata aggacgcttc aatttttgtt tgtctggtcg ccaagttaac
    36181 gggtaattgt cataagaatt aataggcatt ttctccactc cttaaaattg tataccatac
    36241 aattttacca ttgattgtat tgattttaga agttaatctt ttgtgaggag ggaattgtct
    36301 atgaaaatta ttaattttga ggaagtagta gcttctttta gttttgaaga agcgattcaa
    36361 gtaatgaaaa aatgtttttt tgattatgaa agtggtaaaa tcagccaaaa tcctcgattg
    36421 gtggaaattt tacctgacgg aaaaggcaaa aatatgtttg cgatgatgcc tgcttatttg
    36481 ggggagaaca gatattttgg cacaaaagtc attaccgctt ttccggataa tcatcagtat
    36541 catttacctt ctcatttagg agagattttc ttgtttgatg ctcaaaacgg actacccaaa
    36601 gcattgataa acgcaaatgc agtcacctgg attcgaacag ctgctgtatc tgcgctggca
    36661 acagattact tagcaaatcc gcatgcagaa acacttgctt taattggagc tggtcaacaa
    36721 gcattgtcgc atttgactgc gatttctacc attcgtccca tcactacagt gtttgtttac
    36781 gatattttag aagaaagacg aaatactttt atcgctaaag ctaaaaaaca gtatcctaaa
    36841 ataacgttta taaatgcaat atcagtagaa gatgcagtac gtccagcgga aatcatttgt
    36901 acgttgacct ctagtaaaga ggcatttctt caaaaagagt gggtaaggga agacgcacat
    36961 atcaatgctg tgggcacatt tactcctgat acaagagaga taagtacatc gttgatggaa
    37021 acttctcaaa tctatgtaga tgattactca gctgccttaa cagaaagcgg ggacctgctt
    37081 atagccatgg cagaaggaga tttagaggaa tcttgtattg ttggtacatt aggcgaatta
    37141 gtttctgaga aaaaaacatt ttataaagga gaatcgaggc cgacgatttt cgacgcagtt
    37201 ggtctagcta ttgaagatct ttgttgtgca gaatatattt ataacaaatt agagaaaggg
    37261 gctttaaaat gaacttagat tattacgtag ttgatgcatt tgcagatgag gtgttcaaag
    37321 gaaatccagc agcggtttat gtgctagaag aatggctgcc agaaggtacg atgcaaaaaa
    37381 ttgccattga aaacaattta tctgaaacag catttacagt gaagaaaaac caagaatttg
    37441 agcttagatg gtttacgcca gatcgagaaa tcgatctttg tggtcacgcg acattagcaa
    37501 cagcatttgt tttatttaac tattacaaaa tacctgatga aacgattaaa ttttctactc
    37561 aaagcggtaa tctatttgtg acaagaatta aagattatta ttacatggat tttcctagta
    37621 ttatgccgaa aaaagtgccg atattgtctg aatatgaaga agcgattggg gctaagatta
    37681 aagaagccta cttagcacgt gatttatttt tcgtattaga agatgaaaaa acggtggcta
    37741 aattgcagcc agattttaca gctatcaaaa attttgaatt aggaatagga gtcatcgtga
    37801 cagcagaaag tgtgcaaaaa gactttgttt ctagaacctt ctttccaaaa ttaacaatca
    37861 atgaagatcc agtatgtgga tcagcacatt ctaatcttat tccttattgg gcagaaagaa
    37921 tgaataaaac aaaattgtca gcttatcaaa tgtcatcaag gggcggggat ctagaatgtg
    37981 aattaaaaga agatcgtgtg ataataggag gaaaagcagt tttgttttct aaaggtacct
    38041 cgtttatttg atttctttca aatgaattaa aaataaattg gtggagagtg gcaaccttat
    38101 agctacaatg gttgttaaaa aaagacgcaa actttttcaa tttaatgaaa agtttgcgtc
    38161 tcattttaat tattggtgtt tgttttttat tcaatcaaga gtaaaatgcc ccatactaac
    38221 tatcctcgga tgacttcgat tttataacca tcagggtcaa tgacaaagta gtaagaaggc
    38281 gcagtgccag gtaatccttt taagtcagta atctcaagac cagcagcttt atgttgctcg
    38341 tgtaattttt ctagatcatc agctgctata gcgatatgac catagccgtc tcctagatca
    38401 tacgcaccat gatcatagtt gtaagtcaac tctaattcat agtcatcccc aggaagtgtc
    38461 aaataaacaa gtgtaaattt gttttctgga aaatcacggc ggcggctttc ttcaaaacca
    38521 aatgcctttt gataaaattc gattgatgct tcaagatctt tcactcgaac acatgtgtga
    38581 gccattttca tagattcatc tctccttttc cttttactca atcataacaa aaagaagtaa
    38641 ggaaatagtt gatttgtgct tgttcatgag aaatttctca tgtaaaatgg atagaaaata
    38701 aaactgttaa ggtggaaact attcatggat aaaccaattt ttggtgaaaa aaagcaattt
    38761 gctgattatc aaacccgtta tgcagcatat attgtcatag aaagagatca gcagattgca
    38821 gtaatcgagg ctccaaatgg tgcttttttt cttcctggcg gggaaattga aggagaagag
    38881 acgaaagaag aagcgattgt ccgtgagctg atagaagaaa tgggaattgt ggcagaaatt
    38941 tcttcttatc tgggagaagc tgatgagtat ttttactcga attatcgtgc aacttattat
    39001 tataatccag gatatttctt tgttgctgat tcttggaagc gtataggaga accaactgaa
    39061 aagaccaata aaatttggtg ggtgagccct caagaagcgc ttgtgaaatt gaaacgtggt
    39121 agccaccgat gggcagtcga gagatggatc gaaaaaaata aaaactgaaa gaaagcgagt
    39181 agatcagctt tctctcagtt tttttattta ttacagtaca tattttttga ttgcttcagc
    39241 tacaccgtgc tcgtcgtttg atgaagtgat gacatttgct gcttctttga caagagaaac
    39301 ggcatttccc attgctactc ctagaccagc atattcaatc atggataagt cgttctcgtt
    39361 atctccgata gccatgattt catcttgatc aataccaagg tgctgtgcga gattcgcaac
    39421 tgccgcacct ttacttgctt ctttatttag tacttcgaag taatagggcg cacttttgac
    39481 cgttgtgtat ttatcacgga aagtttgcgg taaacgcgca attgctgcat ctaaaatttc
    39541 tggttcgtcg atcatcatca ttttgacgat gttcatgtct ggtgtcattt cttcaggtgt
    39601 tcgatatttt agcggcatct tgactaaact tgcttcgtgg atcgtataag cgctgatatc
    39661 tcgattaggc gtgtagatcg ctttgtcatc gatcgaatgg agatgactgc cgacacggcg
    39721 tgccattact tcgatctcta ggaaatcttc atgtgtcagt ccgtgacggg cgatgatttt
    39781 acctgatttc gtttgttgta cgagtgcccc gttataagta ataacgtaat cattatcttg
    39841 aaaaaggttc aactcgttta actgttcctg gacacctggt aagggacggc cagtgcataa
    39901 aacgatcgaa acaccttttg caacagcagc ggcaatcgct tcttttactt cttttgttac
    39961 ttctcttttc tcatttaata aagtaccatc gatgtcgata gcgactagtt tgatagacat
    40021 aatttcctcc aatatatttt aatttatttc aatcaatgcg ccattacgga tatggctggc
    40081 aaattcttga taagtttcgt caaataaatc ataatgatca cgcaaggacg gatcaaccat
    40141 ttcttttgga aagaaaaatc gctcatctcc ttgttcttgt cccgctaatg cagcaacaag
    40201 ctgactaacc tgtgataatt ctatcaaagt tccgtcattt cgcaaaatct cgatttgtgt
    40261 gcgatgtctg ccttgttctg ggcgataaaa atcataaggt agatcgtagc tagaattcac
    40321 agcagtgtaa taaacaggat tatatccgac cttttctact aacaaagtga gttcttggac
    40381 taattttgaa tcccggttgc cagaaaaagt agcagatttc agtggtttac gattcaaaaa
    40441 acgtttagct aaatcattta aaataggatc agcagattca gaccattgag taaagtaagt
    40501 gcccaagacc ccatcatcaa gtttgaggta ttcttctaaa gtaaagcttc cgtcaagaaa
    40561 tggcagaagt aattgagaat ggagttcaaa actgctggca tcttcttgat acaactcgtg
    40621 tgcgcgatga agcagatgct ccaaaattac ttccatacca cgggaaacag gatggaagta
    40681 cacttgcaca tacatttgat atcggctaac gatataatct tccactgcat gcatgccact
    40741 catggaaaaa gcgatcccgc cttcataagg acgaatcaca cgtaatattc gggtaagatc
    40801 aaatgttcca tattctgttc cagtgaaata agcatcccga agcaaatagt ccattcgatc
    40861 tgcatcgatc tgactagaaa tcatttggac aacttgtggg ttggggtaag ttttttggat
    40921 cacactagct accttttcag gaaaaccttc ttctactcgg ttaagaatct gatacacttc
    40981 tgtttctgga gaagtgatga tctctacagt gatggcttca tgattcgtat ggaagatatg
    41041 ttcaaatgta tgagagtaag gaccatgacc gacatcatgc aacagtgccg cacataaagt
    41101 caccagccgt tcctgatcat cccagcctcc gttgcctatt ttttcttttg aaaaatttcg
    41161 agaaaagata tcgcagattc gtcttgaaat ctcataaacg cctaatgaat gagtaaaacg
    41221 gctatgttct gctccgtgaa aagtgaaaga agaagtgcct aattgtttaa tgcgtcgtag
    41281 acgttggact tctttcgaat tgatcaaatc taagattact tgatgctgga catggatata
    41341 gttatggact ggatcacgaa aaactttttc cataggcagc atttgatatt tataaggggt
    41401 tgtcataatg tagctccttt atgttattac gttgttccat tctctggatt tggttgttcc
    41461 attgctccag ctggatttct ttttttagcc agtcggtaga atcctgtaaa tcacttgcag
    41521 aatacagctt ttcaaaagct tttgcaaatg cttctttgac ttcttttaca aaaaggggtt
    41581 ggtcaagcag ttcttcaagt gttgccattg tagcaggatc cactgcagga tagccatttg
    41641 taccaaagtc ttcttttaaa gcagattgat aaaatcgctt catgacttgc ccacgttttt
    41701 cctgattacc gttgacactt aagtacatca taacagaaat cccatttttg atccgacgct
    41761 gagcgatacc ggcaaatttt ttgccatgga tgcttaaatc ataagttcca ggacaataag
    41821 aatgggtgat ttcgaatgct tgtatcggtg cctttggaaa agcgtattta gtcaatagga
    41881 gcatttgctc gtaagcgtca tctatggtta ttttttttgt gtcactttgg gggaaaatca
    41941 aagaaatatt caaaattcct tcatctgata cgatccctaa tccacctgaa tttctgatca
    42001 ctggagcgta acctgcatct tccagtgttt ggatcccgtc acttagaaaa ggagttcgaa
    42061 catccttcat acctaagatg actgtgcagt catattgcca gaaatgtaaa aagatttgct
    42121 ggtgttcttt agaatattcc gttaatatat ctgttaatgc aaaaggggaa aagtcgtttt
    42181 tttgataaat gtgctgatct agtcgaatcg cagggttcat tcaaccggct cctttgtata
    42241 aattcatatt ttctacaata ttatactcta aaatcaaaga gttgttttgg aaaaaaggtt
    42301 ttctgtaaaa atggacaagt tggttgacaa aacaaaagaa actaggaaca atgtagctat
    42361 gagaagtaaa ggagaatgaa taatggaatt atcacaagga acaccgattt caatcaaatt
    42421 gcgtacaaaa gtaaaacagc aaggggaagt gcaagatttt tattttgatt tgaaagggca
    42481 aatggtgaca attggcgata cgctgtacat acgttataaa gagattcagg aggagacggg
    42541 cgatgagatt cctgtaacga tcaaattagt tccagatggt catgtacagc tgatccgtgc
    42601 aggagaaatg cggatgcgtt tgaaatttgg ctataaagaa cggttagaaa catcctatcg
    42661 aacaccatac ggtatgatcc agattgctac ttttacgaaa gaactgcatg ttagtttgaa
    42721 agaccgtccc acagcaggga aggttcgaat cgattatgat ctgttcatgg gaccggaaaa
    42781 aatcggcgaa tattatttga ccttggattt tacagcgtaa atataaaaga aaagtttgat
    42841 tttttgtgtc tgattttgta tgataaggag tagactgtga aaggacgtgt cctgattgga
    42901 aattagtgta tttgaaggtg caaacaaaag cgaattatca atgatcgaag tagcacacgc
    42961 gatcttagaa caacgtggcg atgtcatgga tttttctgat ttagctaacc agatccaaaa
    43021 ctatcttggg aaatcagaca gtgaaattcg tgattcactc gcacaatttt atactgactt
    43081 gaatattgac ggcagcttta tctcattagg ggataatcgt tggggcttgc gttcatggta
    43141 tgctatcgat tcgatcgatg aagaagtaaa ccatggaatg gacgaagagg atgaagatac
    43201 tccacgtcgc cgtaaacgca agaaagtcaa cgcctttatc aatgatgatg aagacgcgat
    43261 cgattacaat gacgatgacc cagaagatac agatctgaca gaagaagatg acgatgatct
    43321 gtttgatgac gatgatgatg aagatgaaga aatcgctgct tataattctg acttgcaaga
    43381 aatcggagca gatgacccga cagatgatga agaagacttg ccaggaaata tcgaagaaga
    43441 tttaagtatc atagacgaag acgatgatga tgaagattat gaagaggaag aattttctga
    43501 ctctgaaaaa gaataaacat tattttctta cgagaggttg tgacagagac gatcagccta
    43561 tcagaataag gaggtgtgac acgatttttg tcacaccttc ttttttgtat ataaaaatcc
    43621 caagtaaata cataaaaaat aaaaaaattg aaacttttag cgcaccttgt acgtcatatt
    43681 aagtgaggca gaaaggagtg gagaatgatt tttactggat ataagaaaaa acggcagatc
    43741 gaaaaatacc gtcacctgct gaatggactc atcgaaactg attatcaaaa aatgttccgt
    43801 atcacgatga attacgtaca tgataaagaa gaggccttag atgtgatgca agatagtttt
    43861 cataaagccc tgaactattt tgaaaaagaa aaagagatcg agcattttag tgcatggttt
    43921 tatcggatat tgatccgcac ggcattagat agttggcgca gacaaaaaag gacgcctgtg
    43981 gacttatttg aaattcaaga tatcccccaa cagttacctt tagaaacttc cgttgcagag
    44041 ctccatatga ttttagataa aatagacagt ccggaaaaag agattctgat cctctacttt
    44101 tttgaaggat ttcgtttgaa agaaattgcg actatcttgg atatgaatga aaacacagtt
    44161 aaaacgaaaa tgtaccgctc attgaatgct ttacgtcaaa tcctagaatg aaggagagaa
    44221 gagtgccatg tattcccaaa aagaaaattt aaaaaaacta aagaaaactt ataaagaaca
    44281 agcaattccc aaagggctta aagaggagat ccgccagcgt tttattatcg aagagcaatc
    44341 atttataaaa gcaaagcgga gaaagagacg tctccaaggg ttcggagtat ctttggctat
    44401 cgtaatgatt acaacaagta gccttctttt taatagtcaa gttcgaagct ttgcagaaga
    44461 tttacccatc ttaggatcag tcattgaatt gatcttaggc gaacgcttta ctgatcgatc
    44521 tgaaaaaatc gatattcagg taccgaagat caatacacaa aatgagaaag aaaataaaac
    44581 aattcatgga ttaaatcaaa aatactttcg cgaaggacaa gcagattttg aaaaagctga
    44641 aaaagaatat ggaaattttg aaacggatca ttaccaagtt ttgggagatt atcagaaaat
    44701 cgtagacgat aaccggtttc tcgtgattga aaggcagatc acccaaacag cagcagatag
    44761 ccatgttgaa aaaagatacg acacaatcga caagaaaaac agtgtccagc tctcacttcc
    44821 acttttattc aaagatgaca cctatctatc tgttttgaca aaagaagtca aacggcagat
    44881 ggccgaacaa gtcaaggaag atccatctaa gtactattgg actgagcaag atattcaaga
    44941 agggacgata gaaaaaccaa cacttgttac gcctacacga agtttttatt tgaacaaaga
    45001 gcatcaatta gttttgactt tttctcaata cgaaattgct cctggttata tgggtacacc
    45061 agaatttgtc attcctaagt ccgtgacaaa aacgattttg gcatcggaag attatttgga
    45121 tcattagacg agaagtagtt gcgactagca gtttcaattt tcaagtaagt acaagtaaat
    45181 aataagaaga gaaaaagaga aagaagagat atagtgaaaa gaaattattt agttatcagt
    45241 attattgctt tatccgtgct tttgtttttc gaaattactt cggtggcctc cttgatcacc
    45301 gaagtaaaag gacaaacaca ctcttcggag cattcgtcac aatctttcaa acaatcagaa
    45361 caatcaacca ttaaaagcca atcaactgaa acagctaacg tcaaagaagc cattcaagaa
    45421 tcagcggaaa aggtacaaag tcagtcatca caatcaacac aagacagtac aaaaacgagc
    45481 cgagatccgg ctgtcaaaag cgtcgcaatc agctttgatg atggaccagg agcgaccaca
    45541 acaccgcagc ttctgcgaat cttaaaagaa aaaaacgtgc atgccacttt tttcgtctta
    45601 ggagaaaata cggcgcagca tcctgaaatc gtgaagcaga cagctgaagc agggcacgag
    45661 attggcaatc acacatacga tcatcagaat ctggccactc tttctgccca gtcgatgacg
    45721 gaggaagtga cgaaagcaga cactgagatc aaaaaagtca ctggcaaaac ccccactttt
    45781 gttcgtccgc cctatggttc tgtcacgaat gtaggagcaa cgatcatcca gcgaccgatc
    45841 atcgaatggt ctgttgattc agaagattgg aagacaagaa atcctgattt gattttgcag
    45901 aagatccaag caacagtata cgatggggca attattttat tccatgatat ctatcctgaa
    45961 acgattcgtg ccgttcctca agtgatcgat tatctgaaag agcaagggta tcgcatcacg
    46021 acagttgggg atttattagg gcatccaacg gctgtcgaga actattatgg cagaaacgat
    46081 catcggccag ttcagtaagt gagacaagta tctttaataa ataacacatt ttaataagta
    46141 gttgaacaca taactacctt acttgcaaag gcttaacaat atctatacag gtacaacaaa
    46201 aaactgtcca ccaattttct ttggcggaca gttttcactt aaaaataaag aagcaactat
    46261 tcgtaaatta tgctaaaata gcagtagaac gcgtcctgag ggaatcgaac ccccgtctca
    46321 agaaccggaa tcttacgtga tatccactac actaaggacg caagcactgg gataattgta
    46381 actaaacaga taaaaaatta caaggggatt ggacaaaaaa atgaaatttg agcaaaattt
    46441 ttcacaaaaa cagcagcaga cacagaaact agccatgacg caacagttgc aacagtccat
    46501 ccaagtttta caatataaca gtgaggagct gttggcattc gttgagaatc aagcaatgga
    46561 aaatccattg gtggaagttg ttgagccgga atggcagcca gattacataa aagcttcttc
    46621 atcttcttat gaaggagaag agacaaatta cctaaatcag attcctgata caaaagggtc
    46681 tttatttgat tcattgatcg aacaagtcca tttgaattac cgagatactt ttttgaggaa
    46741 aatcgttctt tatcttgtag aatacatcga tttgaacgga tttttgacga ttagtttaga
    46801 agaagccgga aaagagattg gagctacgcc tatccaaatg ctcgatgcgt tgactctgat
    46861 tcagcaatta gaaccagctg gagtaggtgc acgtagtttg caagaatgtc tcatgcttca
    46921 aacagaacga gatgattatg cgccggaatt agcttatatc gtgttggaag aatgttttga
    46981 ggaactggtg gagcgaaaat ggaaagaaat cgcacaacgt ttttctgttg atctacatgc
    47041 tgttcagcag atattcgact atttacaaac gttgagtcca agccctggcc ggattttcga
    47101 ccgtagcagc gaattgtaca ttattcctga tgtccgggta ttagtggacg acgataaaaa
    47161 tgtacaagtt atctcaaacc gaaaaaatca gccaaatata cgctttcaag agagttactt
    47221 caaacaaatg tcacaacaag cagataaaga aactgaaaat tatttaaaag aacggaaaca
    47281 ggaattcgaa tggttgaaga aaacgatcct acaacgtggg gatacaattt tgcgggttgc
    47341 tcaagtcatt gtttcccggc aaaaagcttt ctttatcgac aaggaacgtc caatcaagcc
    47401 tcttacgtta aaggaagttg caactgagat agatgtgcat gaatccacgg tcagtcgtgc
    47461 agtcaacggg aaatatttgg aaacagactt cggtgtattt gaattaaaaa aatttttcac
    47521 tacacgaatt cctacgaata gtacagaaca gacagaagac ctttcagcag atacagcgaa
    47581 gaaaaagctg caggaattag tcgatcaaga agacaaaaac aagccgttgt ctgaccagaa
    47641 attggttgaa ttgctgaaaa aagatgagat agcgatctca agacgaacag tagcaaaata
    47701 tcgtgattta ttaggaatcc cgagttcatc aaaaagaaaa cgttatgata actaatcagt
    47761 caaaagacta gaaaaagtat ttcacttttt ctagtctttt tagttgaaaa acgagagcaa
    47821 aactgttaga cttacagtcg tgaggttgag atttcccttt attgatgtga aattcgaata
    47881 gttaatttct ttttttatcg tatatgggtc gttttaagtc tacattggac gtaaagtgtc
    47941 caactaagga gatcgctatg ctggatgaaa taaaaatgat tgaatctgtt gcaccagata
    48001 ttatcgaagt gttgcaagaa cgctataaaa ttttacgaaa tatctattgg atgcagccga
    48061 ttggacgtcg aagtttatcg gaaagtatgg ggatcacaga acgagtattg cgaacagaaa
    48121 cagatctttt gaaaaatctg aatttgatcg acacctcaaa aagcggtatg acgctgacaa
    48181 ctaagggcga agaagtttat caaagccttg aaaacttcat ggatcagctt ttaggtacgc
    48241 atcaaaccga acaacagttg gcagaatatt ttggtaacca acgctgtatc gttgtttcag
    48301 gaaacagcga agagcagacc aaagtggctg atgcattcgg cgaagcgctg agcgaagccc
    48361 tagaccgact acttccagaa ggcgagaata tcatcgctgt gatgggagga actactatgg
    48421 ctgtggtagc cgaacaattg tctaatctgg aaaataagaa acggcataac ctgtttgtcc
    48481 ctgcaagagg cgggattggt gaagcgataa ctgtacaggc aaattctgtc agtgcaagaa
    48541 tggctgctaa agcaaacggt aaccaccgtg cactttatgt tccggaacaa ttaagtctgg
    48601 caacttacaa ttctttactc aatgagccat ctatccaaga agtcttaaac ttgattagtg
    48661 aagcgaattg tgttattcat agtattgggc gtgcattaca catggcagca cgtcgtaaga
    48721 tgactgaaaa agaattagtc atgctgaaac aagcaaatgc tgttgcggaa tcttttggct
    48781 actttttcaa tgaaaaaggt gaagtcgttt ataaggtccc tagaatcggc atagaattgc
    48841 aagatttgga aaaagtcccg atcatcatgg caatcgcggg cggaaaatca aaagctaaag
    48901 caattcgagc ttatatgaaa aatgcaccaa aacaaacgtg gctcatcact gatgaagctg
    48961 ctgcaaatga gattttaaaa ggggtaaccc tttaaaataa atattttttt gattttcata
    49021 aggaggaaat cttaaatgac agttaaagta ggtattaatg gttttggacg tattggacgt
    49081 ctagcattcc gtcgtatcca agatgtagat ggaatcgaag tagtagcaat caacgacttg
    49141 acagatgcta aaatgttggc acacttgtta aaatacgaca caactcaagg acgtttcaac
    49201 ggaacagttg aagttcatga aggttcattc aacgtaaacg gaaaagaagt taaagtatta
    49261 gctaaccgca acccagaaga attaccatgg ggcgaactag gcgtagatat cgttctagaa
    49321 tgtactggtt tcttcacttc taaatcagca gctgaaaaac atttaacagc tggtgctaaa
    49381 cgcgttgtta tctctgctcc tggcggaaac gatgttccaa caatcgttta taacacaaac
    49441 cacgaaacat taactggtaa agaaacagtt atctcaggtg cttcatgtac tactaactgt
    49501 ttagctccta tggctaaaac attgaacgac aaatttggtg ttgttgaagg attaatgaca
    49561 actatccacg cttacacagg tgaccaaatg actctagacg gacctcatcc taaaggtgac
    49621 ttccgccgtg cacgcgctgc tgctgcaaac atcgttccta actcaacagg tgctgctaaa
    49681 gctatcggtt tagtaattcc tgaattgaac ggtaaattag acggagctgc tcaacgtgtt
    49741 cctgtaccaa caggttcatt aacagaatta gtaacagttc ttgaaaaaga agtaactgtt
    49801 gacgaaatca atgcagcaat gaaagaagct tcaaacgaat cttacggata caacacagac
    49861 gaaatcgttt cttcagatat cgttggtatg acttacggtt cattatttga tgctacacaa
    49921 actaaagtaa tgacagttgg cgacaaacaa ttagttaaaa ctgttgcttg gtacgacaac
    49981 gaaatgtcat acactgcaca attagtacgt actttagaat acttcgctaa cttataagat
    50041 agacaaacgt acaagtgtaa attatagaca tgtacattta aaagcgggga agcaatcgcg
    50101 cttcttccgc tttttttgat aataagttta ttcaggagga aataaaatgg ctaagaaaac
    50161 agtgaaagat atcgatttaa aagacaaaaa agttcttgtc cgtgttgact tcaacgttcc
    50221 tttgaaagac ggcgtgatca ctgacgacac tcgtatcaaa gcagcattgc caacaatcaa
    50281 ctacgttcta gaacaaggcg gaaaagcaat ccttttctct caccttggac gtgtaaaaac
    50341 agaagaagat aaagaaggaa aatctttagc tccagttgca aaacgtctag gcgaattatt
    50401 aggtaaagaa gtaacattcg tacctgaaac tcgcggagaa caattagaag aagcaatccg
    50461 caacatgaat gacggcgacg ttgtcgtatt cgaaaataca cgatttgaag atattgacgg
    50521 taaaaaagaa agcaaaaatg atacagaact aggtaaatac tgggcttcat taggcgatgt
    50581 atttgttaac gatgctttcg gtacagctca ccgtgcacat gcttctaacg taggtatcgc
    50641 ttcaactggt atcccaacag ttgctggatt cttgatggaa aaagaaatca agttcatcgg
    50701 tgaagcagta gaagaaccaa aacgaccaat gattgcaatc cttggtggcg caaaagtttc
    50761 tgataaaatc ggcgtaatcg aaaacttgat tcctaaagca gataaaatct tgatcggtgg
    50821 cggaatgact tacacattct acgaagcaaa aggaatcaag atcggtaact ctctagtaga
    50881 agctgataaa gtggaactag caaaagaatt aatcgaaaaa gcaggcgaca aacttgtctt
    50941 gccaatcgac aatgtctgtg caccagaatt ttcaaatgat gttgaaacac aagtaatcga
    51001 aggagacatt cctgatggtt tgatggcttt agacatcggc ccagcatcag taaaattatt
    51061 tgctgataca ttacaaggtg caaaaacagt tgtttggaac ggacctatgg gtgtatttga
    51121 aatgagtaac tttgctaaag gtacaatcgg tgtttgtgaa gcaatcgcta acttagaagg
    51181 cgcaacaaca atcatcggtg gcggagactc agctgcagca gcagaacaat taggatttgc
    51241 tgacaaattc acacacatct caacaggtgg tggcgcaagc ttggaattgc ttgaaggtaa
    51301 agaattacca ggactagcag caatcaacga taaataaacg accaagtttg ctcaattctg
    51361 acgagtaatc gatcaaaagg tgaagggagt tttcatgact ccctagccat ttttcaataa
    51421 attaaggagt gtgttcctca atgcgtaaac ctattatcgc aggtaactgg aaaatgaaca
    51481 aaactgcatc agaagcaaaa gaatttgctg aagcagtaaa aaacaaaatc ccttcaaatg
    51541 acaaagttga ttcagtcatc ggatctcctg cattattctt acaagaatta atgacatcag
    51601 ctgaaggtac agaactaaaa atctcagcac aaaactgcta ctgggaaaac tcaggtgcgt
    51661 tcactggtga aacttcacca gcagctcttg ctgatctagg tgttcattat gtgatcatcg
    51721 gacattcaga acgtcgtgaa tatttccatg aaacagacga agacatcaat aaaaaagcaa
    51781 aagctatctt tgcaaatggt atgacaccaa tcctatgctg cggcgaatct ttagaaacct
    51841 atgaagcagg caaaactgct gaatggatcg aaggacaaat tacagctggt ttagctgatc
    51901 tttcagctga acaagtgtca aacatggtta ttgcttatga accaatctgg gcaatcggta
    51961 ctggtaaatc agctgacgca caaatcgctg acgaaatttg tggagttgta cgtcaaacag
    52021 ttgaaaaact ttatggaaaa gaagtatcag aagcagttcg tatccaatac ggcggttctg
    52081 taaaaccaga aaatattgct gaatacatgg caaaagaaaa tgttgacggt gctttagtcg
    52141 gtggcgcaag cttgcaagca gattcatttt tgtcattgtt agacgctgta aaataattgt
    52201 tgaaaatttg cgaaaaatgc aagaaatgtt tgcactaatg agcaaaatta actaaaatcg
    52261 tatatgaggg aaatccctta ggaaaaaaca aactcaaagg agagacaaaa catgtcaatt
    52321 attactgatg tttacgctcg cgagatctta gactcacgtg gtaacccaac aatcgaagta
    52381 gaagtataca cagaaagcgg agcttttggc cgcggaatgg ttccttcagg tgcttcaact
    52441 ggtgaatacg aagcagttga attacgtgac ggagacaaag ctcgttatgg cggtaaaggt
    52501 gtaactaaag ctgtcgacaa cgtaaacaac atcattgctg aagcaatcat tggctacgat
    52561 gttcgtgacc aaatggctat cgacaaagct atgatcgctt tagacggaac tcctaacaaa
    52621 ggtaaattag gtgcgaacgc tattttaggt gtttctatcg ctgttgcacg tgcagctgct
    52681 gactacctag aagtaccttt ataccactac ctaggcggat tcaacacaaa agtattgcca
    52741 acaccaatga tgaacatcat caacggcgga tcacatgctg ataactcaat cgacttccaa
    52801 gaattcatga tcatgcctgt tggcgctcca acattcaaag aagctctacg tatgggtgct
    52861 gaagtattcc acgcattagc ttcaatcttg aaagctcgcg gattagcaac ttctgttggt
    52921 gacgaaggtg gatttgctcc aaaccttggt tcaaacgaag aaggttttga agtaatcatc
    52981 gaagcaatcg aaaaagctgg ctatgtacct ggtaaagacg ttgttcttgc tatggatgct
    53041 gcttcttcag aattctacga caaagaaaaa ggtgtttacg tactagctga ctcaggcgaa
    53101 ggcgaaaaaa caactgacga aatgatcaaa ttctacgaag aattagtttc taaatatcca
    53161 atcatctcaa tcgaagatgg attagacgaa aacgactggg acggattcaa gaaattaact
    53221 gacgtattag gcgacaaagt tcaattagtt ggtgacgact tgttcgtaac aaacactcaa
    53281 aaattatctg aaggtatcga aaaaggaatt gctaactcaa tccttatcaa agtgaaccaa
    53341 atcggtacat taacagaaac tttcgaagct atcgaaatgg ctaaagaagc tggctacaca
    53401 gcagttgtat ctcaccgttc tggtgaaaca gaagattcaa caatctctga tatcgctgtt
    53461 gcaacaaatg ctggccaaat caaaactggt tctctatcac gtactgaccg tattgctaaa
    53521 tacaaccaat tactacgtat cgaagaccaa cttggtgaag ttgcagaata caaaggtttg
    53581 aaatctttct acaacttaaa aaacaaataa ttcttttcta atgaagatac atgatcgact
    53641 attgaaagat agtcgagtat gatcacttag ttaagtaatc gaactctcta cttgctgaaa
    53701 tatcagcagg tagagagttt
//
LOCUS       DACCVZ010000010        49104 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.010, whole genome shotgun sequence.
ACCESSION   DACCVZ010000010 DACCVZ010000000
VERSION     DACCVZ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49104
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.010"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            42..854
                     /locus_tag="IVW63_000586"
     CDS             42..854
                     /locus_tag="IVW63_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAP7858887.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            851..1651
                     /locus_tag="IVW63_000587"
     CDS             851..1651
                     /locus_tag="IVW63_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAP7858888.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1812..3080
                     /gene="rseP"
                     /locus_tag="IVW63_000588"
     CDS             1812..3080
                     /gene="rseP"
                     /locus_tag="IVW63_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAP7858889.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3148..4857
                     /locus_tag="IVW63_000589"
     CDS             3148..4857
                     /locus_tag="IVW63_000589"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAP7858890.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            5069..9427
                     /locus_tag="IVW63_000590"
     CDS             5069..9427
                     /locus_tag="IVW63_000590"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAP7858891.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9572..10045
                     /gene="rimP"
                     /locus_tag="IVW63_000591"
     CDS             9572..10045
                     /gene="rimP"
                     /locus_tag="IVW63_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAP7858892.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10068..11243
                     /gene="nusA"
                     /locus_tag="IVW63_000592"
     CDS             10068..11243
                     /gene="nusA"
                     /locus_tag="IVW63_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAP7858893.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11265..11558
                     /locus_tag="IVW63_000593"
     CDS             11265..11558
                     /locus_tag="IVW63_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAP7858894.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11555..11866
                     /locus_tag="IVW63_000594"
     CDS             11555..11866
                     /locus_tag="IVW63_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HAP7858895.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11879..14185
                     /gene="infB"
                     /locus_tag="IVW63_000595"
     CDS             11879..14185
                     /gene="infB"
                     /locus_tag="IVW63_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAP7858896.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14212..14559
                     /gene="rbfA"
                     /locus_tag="IVW63_000596"
     CDS             14212..14559
                     /gene="rbfA"
                     /locus_tag="IVW63_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAP7858897.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14716..14889)
                     /locus_tag="IVW63_000597"
     CDS             complement(14716..14889)
                     /locus_tag="IVW63_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7858898.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            15337..17699
                     /locus_tag="IVW63_000598"
                     /pseudo
     CDS             15337..17699
                     /locus_tag="IVW63_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            18067..18990
                     /gene="truB"
                     /locus_tag="IVW63_000599"
     CDS             18067..18990
                     /gene="truB"
                     /locus_tag="IVW63_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAP7858899.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            18994..19935
                     /gene="ribF"
                     /locus_tag="IVW63_000600"
     CDS             18994..19935
                     /gene="ribF"
                     /locus_tag="IVW63_000600"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HAP7858900.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            20287..21072
                     /locus_tag="IVW63_000601"
     CDS             20287..21072
                     /locus_tag="IVW63_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7858901.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            21085..21936
                     /locus_tag="IVW63_000602"
     CDS             21085..21936
                     /locus_tag="IVW63_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HAP7858902.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(22060..22512)
                     /locus_tag="IVW63_000603"
     CDS             complement(22060..22512)
                     /locus_tag="IVW63_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7858903.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(22977..23345)
                     /locus_tag="IVW63_000604"
     CDS             complement(22977..23345)
                     /locus_tag="IVW63_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HAP7858904.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            23495..23977
                     /locus_tag="IVW63_000605"
     CDS             23495..23977
                     /locus_tag="IVW63_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HAP7858905.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            24014..25024
                     /locus_tag="IVW63_000606"
     CDS             24014..25024
                     /locus_tag="IVW63_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAP7858906.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(25139..25852)
                     /locus_tag="IVW63_000607"
     CDS             complement(25139..25852)
                     /locus_tag="IVW63_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858907.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(26042..26632)
                     /locus_tag="IVW63_000608"
     CDS             complement(26042..26632)
                     /locus_tag="IVW63_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAP7858908.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            27116..27343
                     /locus_tag="IVW63_000609"
     CDS             27116..27343
                     /locus_tag="IVW63_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAP7858909.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            27359..28525
                     /locus_tag="IVW63_000610"
     CDS             27359..28525
                     /locus_tag="IVW63_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAP7858910.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            28759..29802
                     /gene="hrcA"
                     /locus_tag="IVW63_000611"
     CDS             28759..29802
                     /gene="hrcA"
                     /locus_tag="IVW63_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAP7858911.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            29896..30459
                     /gene="grpE"
                     /locus_tag="IVW63_000612"
     CDS             29896..30459
                     /gene="grpE"
                     /locus_tag="IVW63_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAP7858912.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            30510..32339
                     /gene="dnaK"
                     /locus_tag="IVW63_000613"
     CDS             30510..32339
                     /gene="dnaK"
                     /locus_tag="IVW63_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAP7858913.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            32490..33656
                     /gene="dnaJ"
                     /locus_tag="IVW63_000614"
     CDS             32490..33656
                     /gene="dnaJ"
                     /locus_tag="IVW63_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAP7858914.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(33738..34403)
                     /locus_tag="IVW63_000615"
     CDS             complement(33738..34403)
                     /locus_tag="IVW63_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar diacid utilization regulator"
                     /protein_id="HAP7858915.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            34379..34552
                     /locus_tag="IVW63_000616"
     CDS             34379..34552
                     /locus_tag="IVW63_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP7858916.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(34597..35334)
                     /locus_tag="IVW63_000617"
     CDS             complement(34597..35334)
                     /locus_tag="IVW63_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP7858917.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(35336..36838)
                     /locus_tag="IVW63_000618"
     CDS             complement(35336..36838)
                     /locus_tag="IVW63_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP7858918.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            37097..39091
                     /gene="uvrB"
                     /locus_tag="IVW63_000619"
     CDS             37097..39091
                     /gene="uvrB"
                     /locus_tag="IVW63_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAP7858919.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            39101..41917
                     /gene="uvrA"
                     /locus_tag="IVW63_000620"
     CDS             39101..41917
                     /gene="uvrA"
                     /locus_tag="IVW63_000620"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAP7858920.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            42180..43445
                     /locus_tag="IVW63_000621"
     CDS             42180..43445
                     /locus_tag="IVW63_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HAP7858921.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            43449..44180
                     /locus_tag="IVW63_000622"
     CDS             43449..44180
                     /locus_tag="IVW63_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HAP7858922.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            44315..45199
                     /gene="rapZ"
                     /locus_tag="IVW63_000623"
     CDS             44315..45199
                     /gene="rapZ"
                     /locus_tag="IVW63_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAP7858923.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            45196..46194
                     /locus_tag="IVW63_000624"
     CDS             45196..46194
                     /locus_tag="IVW63_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAP7858924.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            46228..47163
                     /gene="whiA"
                     /locus_tag="IVW63_000625"
     CDS             46228..47163
                     /gene="whiA"
                     /locus_tag="IVW63_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAP7858925.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            47706..48356
                     /locus_tag="IVW63_000626"
     CDS             47706..48356
                     /locus_tag="IVW63_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858926.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            48543..>49104
                     /locus_tag="IVW63_000627"
     CDS             48543..>49104
                     /locus_tag="IVW63_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HAP7858927.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT        16422 a         8417 c        10569 g        13696 t
ORIGIN      
        1 cttaagatag tgggaatctt ttaagtatag gaggaaaaag aatgttacgt ttttttccgc
       61 aaaaaaacaa atatattcaa gaaaaaagcg aatttcaatt taataccgat ggaccaattc
      121 ctcagcacat tgccatcatc atggacggca atggtcgttg ggcgcaaaac cgtcgtttgc
      181 cacgagttgc tggccataaa gaaggcatgg aaacagtaaa gaaagtcaca aaaaaagcat
      241 caaggcttgg agtgaaagtg ttgacgcttt atgccttttc gactgaaaac tggaagcgac
      301 caaaagatga agtaagtttt ctcatgcaac tacctgtcga cttctttgat acgttcgtac
      361 cagaattgat taaagaaaat gtcaaagttc atgtcatggg ttatgaaaac gtattgccag
      421 aacatacgca agatgctgta agacgtgcaa ttgagcaaac aaaaaacaat actggaatgg
      481 tattgaattt tgctttgaat tatggaagca gagcagagat cgtgactgct gtccaagaaa
      541 ttgccgaaga agtagcaaaa ggagaaatac acgcagaaga aatcgatgat gaattgattg
      601 ctaagcattt aatgacaggt ttcttgccta aagagttaca agatcctgag ctgatgatcc
      661 gtacaagtgg agaagagcga attagtaatt ttctgttatg gcagatcgca tatagtgagc
      721 tgtattttac aaaagcgctt tggcctgatt ttgatggtgc gcatcttgaa gaagcaatcg
      781 cctcttatca aaatcgagac cgtcgattcg gcggtgtaaa aaaaacagaa gatgagaaag
      841 gggatcagtc atgaaacaac gtgtggtcac agcagccgtg gcgctagtct tgtttattcc
      901 gattatatgg atcggaggca tagcggttga gcttacagca gcaatcttag cagtaatagg
      961 agtttacgag ctgtttcgga tgaaaggatt gacactctta agttttgaag gagttttatc
     1021 cgccgttggt gcagtgttac ttgttttgcc aaaagaaaga tggtttttct ttcttccaga
     1081 gaatgtaagt acatttatgt tattttatct tatagttatg attcttttag gaacatcagt
     1141 tatttctaaa aatacgtata cgattgatga agcaggtttt cctgtgcttg tcagcttgta
     1201 tgtgggaata ggtttccaga attttgtcaa tgcacgaaca gaaagcttgg ctgttttgat
     1261 atttggtcta tttattgttt gggcaactga tatcggagca tatatggttg gtcgacgtta
     1321 tggtcagcat aagttaagtc ctgatatttc gcccaacaaa acgattgaag gtgcgctcgg
     1381 tggtattggt agtgctgttg tagtcgcatt tctttattta ttgctatacc cagcaaaaga
     1441 actatttaat catggtatgt ttgtcatgct tctgatgacg attatttttt cagcagtcgg
     1501 acaatttggt gatttggtcg aatctgcaat caaacgtcat tatgatgtga aagactcggg
     1561 aaatatctta ccaggccatg gtggaatctt agaccgtttc gacagtttgc tgtttgtatt
     1621 tcctatcatg catttatttg gcattattta gtaagtatac ctgcgtttct ttgtgaattt
     1681 cataaaagac gcaggttttt atttttcatt atattgatac tattggtgtc tttggtatac
     1741 tatggtaaaa ttatagtgtt ttatcgttgt tttataaaaa acacaaaaaa caagtaaagg
     1801 agaaaaaagc tatgaaaacg attctgacat ttatcatcgt ttttggtata ttagtgattg
     1861 ttcatgagtt tggtcatttc ttctttgcga aacgatcagg aatcctcgtt cgcgaatttg
     1921 ctatcggtat gggtccgaaa atttatgggc atcaagcaaa agacgggaca acatatacgc
     1981 ttcgcctatt acctattggc ggttatgttc gaatggcagg caatggggat gatgaaacag
     2041 aaatggcacc aggaatgcct ctttctcttt tactaaattc tgacggcatc gtagagaaga
     2101 taaatttaag taagaaaatc caattgacaa atgctatccc gatggaattg agccgttatg
     2161 atttagaaga tgagctgact atcactggtt atgtgaatgg agacgaaaca gaagtagtaa
     2221 cctaccctgt tgatcacgat gcgacgatta ttgaaaacga cggaacagaa atcagaattg
     2281 cgccaaaaga cgtacagttc caatcggcta aattgtggca gcgtatgctg accaactttg
     2341 ctggacccat gaataacttt attttggcaa tcctgttatt catcattctg gcatttatgc
     2401 aaggtggtgt tcaagtgacg aacactaatc gcgtaggaga gatcatgcct aatggagctg
     2461 cggcagaagc aggcttaaaa gaaaatgatg aggtagtcag tgtggacgga aaagaaatcc
     2521 attcatggaa tgatctgaca acagtcatta cgaaaaatcc ggataaaaca ttagacttta
     2581 agatcgaacg agaaggtcag gtgcaatctg tcgacgtgac accgaaatct gtagagtcaa
     2641 atggcgaaaa agttggccaa cttggtataa aagccccaat gaatacaggt tttatggata
     2701 agatcattgg agggacgcgt caagctttca gcggttcatt ggaaattttc aaagccttag
     2761 gatcactatt tacaggtttc agtttagata aattaggcgg acctgtcatg atgtaccaat
     2821 tgtcttcaga agcagcaaat caaggtgtaa caactgttat tagtttgatg gcgcttcttt
     2881 caatgaatct cggaatcgtc aatctgcttc cgattcctgc cttagatggc gggaaattag
     2941 tcttgaatat ttttgaaggg attcgcggga aaccattaag tcaagaaaaa gaaggaatat
     3001 tgacattagc tggctttgga tttttaatgt tgttgatggt gctagttaca tggaacgata
     3061 ttcaacgatt ctttttctag aaaaagttga caaatagggt ataataacaa acgataacta
     3121 ttttgaggaa ataaaggagt atatagaatg agacaatcaa aaatgttgat tccaacatta
     3181 cgcgaagttc caaatgatgc agaagtatta agccatcaaa tcttgctaag agctggatat
     3241 atccgccaag tatcagcggg tatttattca tatctgccat tagcaaatcg tgtattggaa
     3301 aaactgaaac gcattatgcg ggaagaattt gaaaaaatcg gagcggtaga aatgctgatg
     3361 cctgccatct tgccagcaga actttgggaa gaatccgggc gttacgaaac atatggacca
     3421 aacttgtatc gtttcaaaga ccgcaatgat cgaaaaatga tccttggacc aactcacgaa
     3481 gaaactttta ctgatttgat gcgtaatgaa atcaattcat ataagaaatt acctttaaat
     3541 ctttatcaaa tccaacctaa atatcgtgac gaaaaacgac ctcgcttcgg tttgcttcgc
     3601 ggaagagagt ttatcatgaa agatgcgtat tctttccatg caacggaaga aagtttggac
     3661 gagacatata aagattacga aaaagcctac accgaagtat tcaagcgttg tggcttagaa
     3721 tttcgctcga ttatcggaga cggtggcgca atgggcggga aagactcaaa agaattcatg
     3781 gcgatctcag aaatcgggga ggatacgatc tgttattcga ctgaaagtga ttatgctgca
     3841 aacttggaga tggctacaag ctactatgta tcaaaaaaat cgcatgaaac acagcttgaa
     3901 ttggagaaag tagctacacc taacgtaaaa tcaattgacg aagtagcaga tttcttttct
     3961 gttgaacctc aaaaaatcat caagtctgta ttgttcattg cggatgaaca acctgtcctt
     4021 gttttggtac gcggagacca tgaagtcaat gacgtaaaac tgaaaaactt tttatctgct
     4081 gactttttag aagaagcaac agaagaagaa gcacaaaaat atctaggtgc tgagtttggt
     4141 tctgtcggac cagtcggtgt ttcagatgac gtaaaagtat atgcagaccg ttatgtccaa
     4201 gatttagcga atgccattac tggagcgaac gaaacaggat tccactataa aaatgtgaat
     4261 ccagaacgcg atttcactgt actttcttat gaagatcttc gttttgtaca agaaggagat
     4321 ccttcaccag acaacaatgg tgttcttgcc tttactcgag gaatcgaaat cggacatatc
     4381 ttcaaaatcg gcactcgtta cagtgaatct atgggagcaa ctgtactaga cgaaaatgga
     4441 cgagaaaaat ttgtgattat gggctgttat ggtatcggtg taagtcgttt attatcagca
     4501 atcgtagaac aacattcaga tgaacaagga atcaactggc caaaaggaat tgcgccattt
     4561 gatttgcata tcgtccaaat gaatctaaaa gacgaatacc aaacaaacct gacgaatgaa
     4621 ctagaagaag cgatgacaaa agctggctat gaagtactgg ttgatgacag aaatgaacgc
     4681 gcaggagtga aattcgcgga ttctgatttg attggctgtc caatcagaat cactgtcggt
     4741 aaaaaagcag tggatggaat cgtagaagtg aaaatcaaga aaactggcga aatggttgaa
     4801 gtacgtaaag aagaattggt gaatacttta ccaatcctct tgaaccaagg cgaataataa
     4861 gcgttaaaac acagaaaata aaaatagctg aatcagctgt ttttgacaat ctgatgattc
     4921 gcttttaaaa ttggaactgc gatttgaatc gcagttccaa ttttttaatg taaaactcag
     4981 aaaaaacgag tatactaaaa ggtactgaaa aagaagagga taagatgcga tcaattgcat
     5041 tgtttctcat cagaaagggc gtatatcttt gtcagaaaaa cgagatttat ttgaaaaact
     5101 gttggaacaa atccaactag aggaagcaga aaaaaatcat ccactgctta ctgctggtga
     5161 aatggatagt gtagtggtcc atcgtaaatc gcgtttatgg gaatttacgc tgcatttttc
     5221 caaaattttg cctattatgc tatatcggtc attgactcag catctgacta tcgcttttaa
     5281 agatattgca caagtcaaac tgaatatctt agcagatgac cagacattcg atgaacagct
     5341 cttgcaagat tactgggccc aagctttgga aaatcagcaa tgcgatacac cactagcaca
     5401 gcaagtattg aaaacgcagg tacctgtgat aaaagatcgt aaagtcatct tgccaatcga
     5461 cagtacagga gctatttctt atttgaagca acaatacttg ccattagtag aagagttgtt
     5521 cgtcagttac ggattcccaa aatttcgtat cgaaccagaa gtggatgagc agcaagcgga
     5581 acgagtattg aaactttttg aagaacgcaa acaagaacag gcagaagcct ttatgaagca
     5641 agcagctgaa agtctagttg tccacgaaca aaagaaaaag gaaagaaaag agcaatcgcc
     5701 agctcttgaa ggacccatcc acatccagct aggacgaaat attccagccg atgaaccaac
     5761 gacaccaatg atcagtatcg ttgaagaaga acgaagagtc acacttgagg ggtacgtatt
     5821 cgacaaagaa gtcagagaac tacgttcaaa acgcaagatc ttgactttga aaatcacaga
     5881 ttatacttca tcatttatcg tcaaaaaatt ctcgaacggc gaaaaagatg aacaagtatt
     5941 tgatgcgatc agtgtcggta gctggttaaa ggtacgagga agtattcaag aagatacgtt
     6001 tgtccgtgat ttggtcatga atgcgcaaga tatcatagaa gtcaaacata cacctcgcaa
     6061 agattatgct cctgaagggg aaaaacgagt agagcttcat gttcatagca atatgagtac
     6121 gatggatgca acaaacagca tctctgatct tgtggcacaa gcagggaaat ggggacaccg
     6181 agctatcgcc attacagacc acggtggtgc gcaagccttt ccggaagcac atagtgctgg
     6241 aaaaaaagca ggtgtgaaaa tcttatacgg cgtggaagcg aatgtcgtag atgatggtgt
     6301 cccaattgct tataatgatg cacatgaagc attgagtgaa gccacatatg tcgtatttga
     6361 cgtggaaacg acaggattgt ctgcagtata tgacacgatc atcgagctag ccgcagtcaa
     6421 aatgtataaa ggaaatgtga tcgaaagctt tgatgaattt atcgatccag gacatccttt
     6481 gtcacgaaca acggtagatc tgactggtat cacggatgga atggttcgag gatcaaagtc
     6541 ggaagaagaa gtattgcgga tgttccttga attttcaaaa gatacaattt tggtagccca
     6601 caacgcggct tttgatatgg ggttcttgaa tactagctac gcaaggtatg gtattcctga
     6661 agcggccaat ccagtcattg atacgttgga attagctaga tatctgtatc ctcaattcaa
     6721 acgtttcgga ttaggtgtgt tatctaaaaa atttggtgtc agcttggaac agcatcaccg
     6781 agcaatctat gatgctgaag caactggtca cttagcatgg atctttgtga aagaggcaat
     6841 ggacaatcat aacatgcttt atcatgatca gctaaatgag catatcggag aaggagattc
     6901 ttacaaaagg gctcgacctt tccatgtaac gattttagca aaaaatcagg caggactgaa
     6961 agatttgttc aaactgattt caatgtcgaa tgtcgaatac ttcgaacgcg tcccacgaat
     7021 accacgctcc caattgaaaa agatgcgtga aaatctattg atcggctcag cttgtgataa
     7081 gggagaaata ttcgaagcca tgatgcaaaa aggggtagaa gaggcaagaa accgagcaaa
     7141 attctacgat tatattgaag ttatgccaaa agcggtctat gcgcctttga tcgagcaaga
     7201 attggtaaaa aatgaacatg atttggaaga aattatccaa aatttggtag aaatcggaaa
     7261 aagtttggat aaaatcgttg ttgcaacagg taatgtacat tatctgaacg aagaagatgc
     7321 catttaccga aaaattttga tcaattctat gggcggagcg aatccgttga atcgtcatag
     7381 tttgccggat gtccatttcc gaacaaccga tgagatgcta actgcatttc actttttagg
     7441 ggaagaaaca gcgaaagaga tcgtagtaga aaatacgaat aaaatcgcag atatctgcga
     7501 agaagtgatt ccagtcaaag atgaacttta tacaccgaag attccaggtt cagaagatga
     7561 aatatcagaa ttgagttaca caaaagcaaa acaaatgtac ggagatccgt tacctgagat
     7621 cattcaaaaa cgattaaaaa aagagttgaa ttctattaat ggtaatggct tctcggttat
     7681 ttatctgatc gcccaaaaac tagtgcataa aagtaatgaa gatggctatc tagtaggttc
     7741 acgtggctct gttggctcta gctttgttgc gacgatgaca ggaatcactg aagttaatcc
     7801 gttagcccct cattattatt gtccagagtg ccaatattcc gagttttttg aagatggtac
     7861 gtatggttct ggatttgaca tgccagaaaa acaatgtcca aaatgtggtg cacgcttaaa
     7921 caaagacggt catgatattc catttgagac atttttagga ttccatggag acaaagtgcc
     7981 cgatattgat ttgaacttct caggtgatta tcaagcagaa gcccataact atacgaaagt
     8041 attgtttggc gaagactatg tttaccgtgc cggaacgatt ggtacagtcg ccgacaaaac
     8101 agcatatggc tatgtaaaag gatacgaaag ggacaataat ctgcagtttc gaagtgcaga
     8161 agtcgacaga ttagcaaaag gcgctactgg agtcaaacgg acaaccggcc agcatccagg
     8221 ggggatcatc gttattcccg attatatgga tgtctatgat tttacgccga tccaatatcc
     8281 agcagacgat caaaattcgg aatggaaaac gactcatttt gattttcact cgattcacga
     8341 taatgtattg aaattagata ttctagggca tgatgaccca actgttattc ggatgcttca
     8401 agatttatca gggatcgatc cacaaacgat ccctacggat gacccggaag tgatgcggat
     8461 atttgccggt cctgaagtac ttggagtaag tcaggaacaa atttattcca aaacagggac
     8521 attaggtatt ccagaattcg gcactcgttt tgttcgaggg atgctagaag aaacgcatcc
     8581 tacaactttt gcagaactac tgcaaatttc cggactatct catggtacag acgtatggtt
     8641 aggaaatgcg gaagaattga ttcgacgagg agatgcgaca ctggcggaag taatcggctg
     8701 tcgtgatgat attatggttt atttgatcca tgctggatta gatagcggga tggcatttaa
     8761 aatcatggaa actgttcgta aaggacaatg gaacaagatc cctgatgaat tgcgagaaac
     8821 ctatctatcg gcgatgaaag aaaataatgt gcccgactgg tatatcgatt cttgttcaaa
     8881 aatcaaatat atgtttccga aagcccatgc tgcagcttac gtattgatgg ctcttcgtgt
     8941 cgcttatttc aaggtttatt tccctatttt gtattactgt gcatactttt ctgtacgtgc
     9001 agacgacttt gatctagtct ccatgtgcaa aggaaaagat gctgtgaaac aagcaatgaa
     9061 agaaatcacg gacaaaggat tagatgcttc cgtaaaagaa aagaatcaac tgacagtgct
     9121 ggagttagcc aatgaaatgc tggaacgagg attcaaattt ggaatgattg atttgtataa
     9181 atcggatgcc gttaactttg ttattgaagg tgatacgttg atcgcaccat ttagagctgt
     9241 cccaagtttg ggaaccaacg tggcaaaaca aatcgttgaa gcaagaaaag acggtccatt
     9301 tttatccaaa gaagatcttg ccacccgcgg taaagtttca aaaacattga tcgaatatat
     9361 gaacgacaat ggcgtattga aagatctacc agatgaaaat caattatcgt tattcgatat
     9421 gctataagca tctgttttcc tgtctgcttg taattttaag cagagtatgg tatagttctt
     9481 ataggtaatg atactaactg tgagtgagcg gatttttcgc tcactctttt taatggaatt
     9541 acgcacttaa ttttttaagg aggcgaaact tttgagtagc gtcgttgaaa cagtcacaga
     9601 aatggtgaca ccgattttag atgaacaaaa ttttgaactt gtcgaagtcg aatttgtaaa
     9661 agaaggaaaa agctggttct tacgagtatt tattgacaaa gaaggcggta tcgatatcga
     9721 agaatgcgcc tttgtcagtg agaaactgag tgaaaaactt gatgcagcag atccagatcc
     9781 gattcctcaa gcttatttcc tggaggtatc ctccccggga gcagagcggc cattgaaaaa
     9841 agaaagcgac tatgaaaagg cacttggtga ttatgtccat gtctccttat accaaccagt
     9901 agatggcgaa aaacaatatg aaggatttct tcaatcattt gatgctgaac agcttacatt
     9961 gaaaatacgc ataaaaacac gagaaaaaga attgactttt gaccgaaaaa atattgcaaa
    10021 agctcgctta gctatccaat tttaatcacg gagaggaatc agaaaaaatg agtaaagaaa
    10081 tgttaaatgc gttagacgct ttagaagctg aaaaagggat ctcaaaagaa atcgtgatcg
    10141 atgctttaga agcagcattg gtttctgcat acaaacgtca ctatggccaa gcacaaaacg
    10201 tcgaagtgga atttgatcag aaaaaaggaa agatccatgt ctatgcggta aaagaagtaa
    10261 cggaagaagt gatggattca cagttggaag tctcattgaa agatgcactt ttaatcaatc
    10321 cagcatatga gatcggtgat acgatccgtt ttgaagtaac accaaaagat tttgggcgga
    10381 tcgctgcgca aacggctaaa caagttattt tacagcgtgt acgtgaagca gaaagaacga
    10441 ttatttataa cgaattcagt gcttatgaaa aagacatcat gcaaggaatc gtcgaacgcc
    10501 aggataaacg ttatatttat gtcaatcttg gtaaaattga ggcagttctt tctaaacaag
    10561 atcaaatgcc aaatgaattt tatcaaccac atgatcgaat caaagtttat gtttcccgag
    10621 tagaaaatac gtctaaaggt ccgcaagtat ttgttagccg cagccatcca gacctattgc
    10681 gccgcttatt tgagcaagaa gtaccagaag tctatgatgg aatcgttgaa attgtcagca
    10741 tcgcccgtga agctggcgat cgttcaaaag tggcagttcg ctcaaatgat ccaaatatcg
    10801 atgcagtcgg tacatgtgtc gggccaaagg gacaacgagt tcaagcaatc gtcaatgaat
    10861 taaaaggcga aaacatggat atcgtcgaat ggaatgaaga tccagctgta ttcattgcaa
    10921 atgcattgaa tcctgcacaa gtcatggatg tgatcttcga tgagacaaat ccaaaggcct
    10981 gcacagttgt cgttccagac taccaattat cgctagcaat cggtaaacgc ggacaaaacg
    11041 cacgtttagc tgctaaattg actaaccata aaatcgatat caaatcagaa tctgacatga
    11101 cggaatttta tgaaaatcaa gaacaacaaa aagaaacaga agaactgcat gatgaagcaa
    11161 tcgttcagtc agatttaaca gacgatgaat atgaaacaat tgcattcaac aatgaaacgg
    11221 tcgaagaaaa accagaagct taactttagt aaggaggcaa agagatgaaa caaaggaaaa
    11281 ttcctttacg caaatccgtg gtttcaggtg aaatgaaacc taaaaaagag atggtccgaa
    11341 tcacccgttc aaaagaaggg gaagtatcga tcgatccaac tggaaaaatg cctggacgag
    11401 gagcgtatgt ctcacttgag ccggaagaag tacaacaagc ttgggataaa aaaattctcg
    11461 atcgagtact cgaaacaaca ttaacagatg agttttatca agaacttctt gactatgtca
    11521 ctcaccaaaa agcacgtaaa gagttatttg gaaaatgaat acagttaatc ggcaaaaagc
    11581 catgaatctc atcggtctag cgatgcgcgc gggaaaacta atcacgggtg aagaactgac
    11641 cattgctgaa atccgcaaac aaaaagcaaa attggtgttt gtggcaaccg atgcaagcga
    11701 gaatacaaga aaaaagataa aagataagag ttcatattat gaagttcctt gctttgagct
    11761 attttctgaa gcagaaatca cgcagatgat cggaaaacct cgcaaggtat tcggaataat
    11821 ggatgccgga tttgcgaaga agaccaagga gctaattgaa ggttaggaag gtgattgcat
    11881 gggcaacaaa agaatctatg aattagcaaa agaactcaaa aaatctagta aagacgtcgt
    11941 ggaaaaagca caacaacttg gcatcgatgt gaaaaaccat atgggtgcga ttactagcaa
    12001 tgatgagaag aaattgcaac aagcgttcaa aaacccaagc acgaaacaac aagctgcaca
    12061 acaagcaagc agaaaaccag ccaatcaaca gccgaacgat caacgtaaaa aagaaacaac
    12121 gaacaatcaa caaaaaaata aaaataaccg cagttatcaa gatcgcggtc aagggagcgg
    12181 tcaagtgaat caaggaaaaa aaccaacaac aaaccaaaat aatacgggaa ataccagcag
    12241 ccaaaatcgt caaggaacga gccaaggcgg caatcaaaac cgtactaaca ataacaacaa
    12301 accaaacaat aacaatcgcg gcaaatttaa taataataac cgtaatcgtt ataataaaaa
    12361 aggtaaaaaa ggcaaacagc aacaatcaac taaaccagct gtaccaccac gcaaattccg
    12421 tgaattgcca gatgtattag agtatactga aggtatgaac gtagcagata ttgcgaaaaa
    12481 aattcatcgt gagccagcag aaatcattaa aaaattattt atgcttggtg tcatggtcaa
    12541 tcaaaaccaa gcactggata aagatacgat tgaactgtta gcgacggact atggcatgga
    12601 accacaagaa aaagtccaag ttgacattgc tgatatcgat aaattcttcg aggcagaaga
    12661 agtcgatcca gataaattag tctcacgtcc gccagtcgta acgattatgg gacacgtaga
    12721 ccatgggaaa acaactttat tggatacatt acgccattca cgtgtaacaa gcggcgaagc
    12781 cggcggaatc acacagcata tcggtgccta ccagatcgat attgatggta aaccaatcac
    12841 tttcttggat acaccaggac atgcggcctt tacaagtatg cgtgcacgtg gagcaagtat
    12901 cacagatatc acgatcttag ttgttgctgc agatgatggc gtcatgccac aaacagttga
    12961 agcaatcaac catgccaaag ctgcaggcgt tccaatcatc gtcgctgtaa ataaaattga
    13021 taaaccaggt gcaaaccctc aacatgttat gcaagaatta agtgagtatg agttaattcc
    13081 tgaagcatgg ggtggagaaa cgatctttgt tgagatctca gcgaaattcg gccaaaacat
    13141 cgaagaattg ctggaaatga tcctgttagt cgcagaagta gaagatttaa aagcagatcc
    13201 aacacaacgc gcaatcggaa cagtgatcga agcacgtctt gataaaggta aaggtcctgt
    13261 gtcaacctta cttgtccaag aaggaacact tcatgttggt gacccaatcg ttgtcggtaa
    13321 tacttacgga cgtgtccgtg taatgacaaa cgatcttggc cgtcgcgata aagaagcagg
    13381 acctgcaacg ccagtagaaa tcactggctt gaatgatgta cctcaagcag gtgaccgttt
    13441 cgtagtcttc gaagacgaaa agacagcacg tgcagcgggt gaagaacgcg cgaaacgtgc
    13501 attattagaa aaccgtgctg ccacaagccg tgtgactttg gataacttat ttgaaagcct
    13561 gaaagaaggc gaattgaaag aagttaacgt aatcatcaaa gcagatgtac aaggttcagc
    13621 agaagcactg gctgcatcat tgaagaagat tgatgtggaa ggtgtccgtg taaaaatcgt
    13681 ccattcagct gtcggagcaa tcaatgaaag tgatgtaacc ttagcagcag ccagcaacgc
    13741 tattatcatc ggtttcaacg ttcgtcctac accgcaggca aaagtgcaag ctgatactga
    13801 agaagtcgat attcgtcttc accgtatcat ctataaagcc atcgaagaaa tcgaaactgc
    13861 gatgaaaggg atgctagacc ctgaatttga agaaaaaatc accggtcaaa tgatcgttcg
    13921 tgaaaccttc aaagtttcta aagttggtac gattgcaggt gcctatgtaa cagaaggata
    13981 tattcgtaga gatagcggtg tccgtgtaat ccgtgacgga atcgtaatct atgaaggcca
    14041 acttgcaagt ctgaaacgat tcaaagatga cgtgaaagaa gtcaaaatgg gttatgaatg
    14101 tggtgcaatg attgaaaaat tcaatgacat caaagtagat gacgtaattg aaggatttat
    14161 catggaagaa gtcaaaaatg actaaaaact gataaaagga ggccaatcat tatggctaac
    14221 taccgtgacc gccgagtcgg tcaagaaatc ttaaaagaag tcaatgatat tttgcgcaaa
    14281 aaggtccgtg accctcgtgt ggagaacgta acgatcacag atgtgaaagt tacgggggac
    14341 ttacagcaag caacgatcta ttacagcatt ttatctgact tagcatcaga taagaaaaca
    14401 gcacaagatg gattgaataa agcatcagga ttgattcgtc gagagttagg gcacaatcta
    14461 agtatttata agacacctga attgttcttt gaacttgatg aatcagttgt ctatggcaac
    14521 catatcgatg aattgcttcg cgacttgaac aaagactaat caaaaactcc cgcaaatcct
    14581 gtgaaatcag gggttgcggg atttttttgt tttcattaag acgtattacc taagagttcc
    14641 atgactttag tcttgcggcg tgtcagctaa ccaaaaaaga gaaaaagaaa agtaaaaaat
    14701 tcgactttct tttttctagt agtatataaa tttttgcata tagataaaga tcaagatacc
    14761 gataacggaa gctagattgt aatctatttt agtgacagtc aggtatagcc aagtaactag
    14821 aagatcagtg gaacctgcac cataaaagtt tgagtttgtc ggtccgttga cagttaaaag
    14881 aaaaatcacg ttgaagttat tgatatttcc gattacgccg cttcgatttg gtcacgatcc
    14941 aaattttgga taatccctgt agaaattagc atagtagctg ggataccaat tcacatattg
    15001 acaaagataa cagagacttt tacataaaac ggatcaatca ggaaaggaat tgctcgatcc
    15061 agccccagtt ttccagcaat gtgttaactg gcccagcgtc attcagcaaa ttatgcatga
    15121 tgaggagcga aatgaactgc ggaacagcca ttgtgataac gacaagtttt ttggatcaat
    15181 gtaaaaaacg tcagcgaaag gaaaaatttc gtggtttttt atacctgttc atttggctag
    15241 atataaaatc caaacaaatg aacagaagtg cttattaggt ttcaattggg agtatctgcg
    15301 ctagaataag agtaataatg aaaaggagtg ttatgtatgg attattctag taaagaatac
    15361 tttgataaaa tgacggcttg gtggcgtgct gctaattatc tttctgttgg gcaactttat
    15421 cttaaagata accccttact gagacgtaca ctgaaacccg aagatgtcaa aaaacatcca
    15481 atcggtcatt ggggaacgat tcctggccaa aattttattt atgtccattt gaaccgagtc
    15541 atcaataaat atgatttgaa catgttttat attgaagggc caggacacgg cggacaagtc
    15601 atggtatcga atgcttattt agatggaagt tacacagaga tctatccaga agtaacggaa
    15661 gatgagacag gaatgcaaaa attattcaaa cgattttcat ttcctggagg cattgcttct
    15721 catgcagcac cagaaacacc aggttctatc catgaaggcg gagagcttgg atactctctt
    15781 tcacatgcag tcggagctgt attagacaat cctgaagtaa tctctgctgt cgtgattggt
    15841 gatggtgaag cagaaaccgg tcctttagct ggaagctggt tctcaaatgt ctttatcaat
    15901 ccagtgatag atggagctgt tttaccgatc cttcatttaa atggtgcaaa aatagccaac
    15961 ccaacgatct tggcacgtaa atcagatgga gaattagcaa attactttaa cggacttggc
    16021 tgggaacctt tctttattga aggaaatgat tcagaaaaat taaatcctgt tatggctgaa
    16081 aaaatggatc aagcaatcga gaaaattaaa tccatccaaa aagaagctcg cctgaagaca
    16141 gcaacagatg tcgtgatgcc aaaatggcca gtattgatcg tacgcacacc aaaaggatgg
    16201 accggtccaa aagaatggga cggggaacca attgaaggaa ccttccgagc acaccaagta
    16261 ccgattcctg tagatcaaga acatatggat catgcagatg ctttactccg ttggctgaaa
    16321 tcctatgaac cagaaaaatt atttgatgca caaggacgta ttttagaaga aatcagagaa
    16381 atcgcgccta ctggtgacca aagaatggca aaaaatccta tcaccaatgg tggaatcgat
    16441 ccaagaccgc ttattatgcc agattggaaa aaatatactt tgcaatttga aaaaccaggc
    16501 tccgttaaag cagaagatat gaccgaactt ggtaaattcg ttcgcgagat cattgagaaa
    16561 aatccagaaa atttccgtat atttggacca gatgaaacaa aatcaaaccg attgaatcaa
    16621 gttttcaaaa cgacaaatcg ccaatggatg gaaaaaatcg aaccagaaaa tgatgaatgg
    16681 ctttcgccat ctggtcgcgt catcgacagt caattatcgg aacaccaaga tgaagggttc
    16741 ttagaagggt acgttctgac tggacggcat ggttttttgc aagttacgaa tcattcttgc
    16801 gagtggttga ctctatgttg actcagcact tcaaatggat gcggaaatca catgaccttt
    16861 cttggcgaaa tgattatcct tcgctaaatc tcattgcaag ctcaacagtc ttccagcaag
    16921 atcacaatgg atatagccac caagatccag gaatattgac acatttggca gaaaagaagg
    16981 cggagttcat ccgtgaatat ctgcctgcgg atgcaaatac attgctcgca gtcatggata
    17041 aagcattccg ctcgtcagaa aaaatcaatt tgatcatctc ttccaaacat ccgcgtgctc
    17101 aattttactc agcagaagaa gcagccgtct tagtgaatga aggcttgaaa atcattgatt
    17161 gggcttcgac agcaaaagag gaggaacctg aattggtcat tgctgctgca ggaacggaat
    17221 ctaacttaga agcattagca gctgtaactt tgctgctgga agaattccca aaactaaaaa
    17281 ttcggttcat caatgtcgta gatttattga aattacgtca tccaagtcaa gatccgcgtg
    17341 ggttgagcga tgaagaattt gatcaatatt ttacaaaaga caaaccgatc ttatttgctt
    17401 tccacggtta tgaaacattg gtccgcacga ttttctttga tcgtcataac catcatttaa
    17461 tgattcatgg ctacaaagaa aatggagata tcacgacacc atttgacatg cgtgtagtaa
    17521 atgaacttga tcgttatcat ttggcaaaag acgcagcttt aaaaatcaaa ggaagtcaag
    17581 cagaagattt tgcgaaaaaa atggatcaga aattacaaga acatcaaaac tatattcgtg
    17641 aaaatggtat tgatctgcca gaagtattgg attggaaatg gaaaaatctt gaccaataaa
    17701 atgataaaat cgatcccgca aaatagaatt ttttacattg attaagaaac tgaaaaaata
    17761 aataaaaaaa acggaaaaaa gactggaaga atggccagtc ttttttttcg tttttgggaa
    17821 gtgaaaacca aactatttac ctgtaagcca cccataaatc caatcaaatg gtgcaaagaa
    17881 aaaatcttcc attctattcc ctcctttaaa aaagcataac atgatttcta tttacgtgag
    17941 catgaatttt gttacgtttt tattgccgaa aaataaaaac cgttcattat gatgtcaaat
    18001 tcgtcagtaa ttgatgcaat gtgttataat aattcagtta aatcaaaaat gaaatggaga
    18061 aaagacatgg acgggttatt acctttatgg aaagaacgcg gaatgacaag tcatgattgc
    18121 gtattcaaat taagaaaaat cttacatacg aaaaaaatcg gacatggggg tacgcttgac
    18181 ccagacgtag acggtgtgtt gcccatttgt attggaaaag ccacaaaagt tatcgaatat
    18241 ttgacagatt ctgggaaaat ctatgtaggc gagataactc taggtttcag tacaacgacg
    18301 gaagatcgat ccggagaacg ggtagaaaca aaaccagtag atatgtcttt atctgaaaaa
    18361 aaaatagatg aagtgatggc ttcatttatt ggtgagatca cccagatacc accaatgtac
    18421 tcagcggtaa aagtcaacgg taagcggtta tatgaatatg cccgcaataa tgaaacagtg
    18481 gagcgtcctg ttagaaaggc tcagatttac cgttttatcc ggacaagtga attgacaaga
    18541 gacgaagtga caggaaccat ttcttggcgc ttcgaagtag aatgcgggaa aggaacctat
    18601 gtccgcacat tagctgtaga tacaggcaag aaacttggtt accctgcgca catgtctgat
    18661 ctgacccgaa cagcaagtgc cggtatgtcc cagaaggatg ctctgacatt agaagaagta
    18721 gctcaagctg tgaaaaatgg gacaatcgat gattgtttgc tgccaataga aaaaggagtg
    18781 gaacggttca aacgagtaga tattactgat gaagtatggc agaaagtaaa aaacggtatg
    18841 agacttgatt atactgtatt tgcgctccca gaaatgccgt cagaagaaat tgctttgttt
    18901 tataaaggaa aagttgtcag tatttatcag ccaaacccga aagaaaaaaa caaattaaaa
    18961 cctagtaaag tattgagaaa tgaggaataa cgaatgaata tcatcaagat cagacatcct
    19021 taccaatcag aacaaattcc agaagacgat gtcgttttag tgctgggatt tttcgacggc
    19081 gtgcatatcg gacaccagaa agtcataaag acaggtatgg aaattgcaca aaaagaagga
    19141 ttgaaattag cattgatgac tttcaatcag catccatcta ttgtctttaa aaagatcgat
    19201 cctagcagcg tgaaatattt gactagcctt aagcaaaaag aagaaaaaat ggccgctttg
    19261 ggtatagatt atttatatga agttgatttt acttcttctt ttgctcattt agcaccgcag
    19321 gaatttgttg atcaatacat cgtagggtta catgcaaaat atgctgtttc cggttttgat
    19381 tatacgtatg gaccaaaaga cattgcagat gtcgctcatt ttcctgaata tgccaaagga
    19441 agattcaaaa tcgtcacagt ttctaaagaa gaagaacaag gtgaaaaaat cagctctacc
    19501 cgtattcgtg gattactaga cagcggacaa gtaaaagaag cagcaaaact attaggttgc
    19561 acatatgagg tagaaggggt agttgtccat ggcgatgcac gaggcagact actaggattc
    19621 cctacagcaa atgtcaaagt aaagagcacg gttcatttgc ctaaagaagg tgtttatgtg
    19681 tcggaaataa aaattgggga aacatggtat ccagccatgg gttcaattgg acataatgat
    19741 acattcggtg aaggacggga gctgactgta gagttgtata ttttggactt taatcaagat
    19801 atctatggtg aacatgtcgc ggtacgctgg aatcaatttt taagagatca agtgaaattt
    19861 tctagtgtag aggaattgat tgaacaactc aaggaggatg aacaagcaac agctgaatat
    19921 ttttctcagc aataaaacat tatgcataaa atctcttgtt tatgtataac tagcaattac
    19981 aataaaatgg gtgataaata agcccaggaa aggggctgtg acaaaagtct tgtcacagcc
    20041 tttttttcca aataaatggt ttttcagaag tagcttcttc ggaaataagc cgaaatttct
    20101 tgaagctgac cacttctgtc acaacctctt tctttataga aataaaagga cactagcaat
    20161 tcatgaaaac gattgctaga gcgtatcatt tgctttagac tatatatctt ggtgtacact
    20221 cactttaagg cggaaataaa agttatccgt aataacaggt ttaggtatga aaaaggagtg
    20281 ggtactatgt acaaggaatt agaaaacaaa gtcgcagtag taactggtgg ctcaaagggg
    20341 attggaacag cgattgctca acgattcggg aaagaaaaaa tgaatgtagt tgtcaactat
    20401 aactcggata aagaaggagc agaaaaagca gtcaaagcaa tcgaagaggc aggcggaaaa
    20461 gcagtctctg tacaagcaga tgtcagttct gaagaaggaa tacagcgttt acttgatacg
    20521 gctttagaaa attttgggac actggacgtt tgggttaata atgctgggat ggaaaatcag
    20581 catccaaccc atgaacttag ccttgaagat tgggaaagag tgttaaaagt caatttgact
    20641 ggcgttttta tcggaacgaa agcggcttta aattacttta cagagaataa taaaaaagga
    20701 aatatcatca atatgtcttc tgttcatgaa cagatcccat ggccaacgtt tgctcattac
    20761 gctgcttcaa aaggcggggt aaaattattt accgaaacgg tagcaatgga gtatgcaccg
    20821 aagggaatca gaatcaatag tataggccct ggtgctatcc gtacacctat taatgcggca
    20881 aaatttgatg atcctgaaca aaaagaactc ttggaaagta tgatcccact aggacgcgta
    20941 ggtgaaccaa aagaaatagc ggcgacagct gcatggttgg cttcagacga atccagttat
    21001 gttacaggta ttacactatt tgcagatggt gggatgactt tatatccttc tttccaaggt
    21061 ggaaaaggat aagggtgaat aaaaatgggt ttattgattg cattgatccc ggcagttggc
    21121 tgggggatcc agccactgat tttgaaaaag attggtggca gaccaacaaa tgagatatta
    21181 ggaactggta ttggagcggt gcttgtcggc ttactcgttc aattattcgc ttctccagct
    21241 ggtatttcag tgactacatt tttgattagt ttactttctg gtgcattttg ggttattgga
    21301 caaacaggac agtatacatc tttcaacttg attggtgttt ctaaaacgat gccaatttcg
    21361 actgcattac agttagtcgg aacctcgttg attggtgtct tcgcttttgg agaatggtct
    21421 ggaagtatgg ggaaaatcat tggagcagca gcaatcattc ttcttgtatt tggttctgct
    21481 ttaacggcaa tcagtgatga tcctggaaaa aaaggcggta tcacaaaagg aattagtcta
    21541 ttagcatcaa caagtattgg ttattgggta tacagtgcat tgcctaaact agttgatgca
    21601 agcggacttt ccattttctt tccgcaaatg atcggtgtct ttttaggggc agtgatttat
    21661 gtgattttcc gtaaaccaac cgcattttct gaagacaaga gttggaaagc aacgatcgtt
    21721 ggagccatct ttagtgtgtc agcattggct tatatttttt cagcaaatga aaatggggtt
    21781 gctactgcat atatcattac acagctaaac gtagttatct ctacattagg cggtatgtac
    21841 atcctgcatg aaaataagac accaaaagaa aaaaaattaa cgattatcgg attattgctg
    21901 atcgtagtag gaagcatggt cacggtcttt atttgaggat aaagatggta aaatttcatt
    21961 tattaaaaaa atatttgttt gaaccaaaca gtaagtactt ataaaaaaat agcgctagaa
    22021 tttccaacat ctctggaatt tctagcgctt tttaattgtt taagatacaa gggaaatatc
    22081 tgtctggatc aataattttt cattgatcca ttgactaaag tttacgacat aattgaagtt
    22141 accaccgatt agtatctccg catgattgtc tttataaaga tcgtattgta aaagacggtc
    22201 ttttttattt gcgtaaacat cgttatggta ctggactaat tgttctcgga attgattgat
    22261 tgctgtaaaa tcacgatatt gaaggttgaa acgcatcgtg attggtgcat ttagcatgaa
    22321 tcgctgcatt tcttttgctg cttcctctgc ttgatctccg tataggaact caaaaagatt
    22381 acgttcagaa aatttccatt gcccgccaac ctttgttcct tttagttttc cttcatgaag
    22441 ataatttctg atagaacgtg tagtaacacc taattgttcg gctaattcat ttactgagta
    22501 aaaatctttc aatgttcacc ctcctatgtg aatggttcta ctgacttagt tgatatttgc
    22561 ttaatcacga aatgtagaaa gaacgatttt aattaaggtc attgtaaaaa tcaagtcaga
    22621 aaattctaac ttttatttct ctaaagaaat tcgttctctc ctaaagtgat attatattta
    22681 aatatacctg aaaataatgg gcagtattat gaaagatcac tgatattttc tcgtattttt
    22741 tccttattca aaagttttgc aggaaaattg ctgaaaaaat aattttacta agtagaaaat
    22801 tcaaagccat tcaatcagtg atttttttca gcacaagaaa gactccttat aaaaatagca
    22861 gatactttgt caattaagtg tttaaccagg gatgataaaa aggataggat tgaacaaaac
    22921 ctgtataagg tgatgaatag tttcctcgcc agtaaaaggt ttattcgtat aaagctttat
    22981 cgccaaaatt tatcatgacc ttttttatct tcaatattaa atgaaatcaa ttgttcaatc
    23041 aattcccagt tgattacact tttccaagga actttgatga cgttatccgt atatacgtag
    23101 cctgcttctt ggatattttt ttcaagggca cgaatcgctg ctttttccgg tgcgatagaa
    23161 aaatgatttt tagcaaaact aaatgcaata ataaaggtac catggtcagt aaacataggt
    23221 tggttccatt ttacagttgt gtctagctgg ggatacgttt ctgttatctt agcaaaaagg
    23281 tctttgatct tttgttgatg ttctttttct ttgatttgat tgatgatcgg ctgaaatttt
    23341 tccattctaa aacgcctcca ttaagtggtt tgatttattt taccagaaaa acaatagtta
    23401 tgtataaaaa acgaacaaaa cacaagtaat gttgtaaccg ctatatttat atgataagat
    23461 gtctcaaata ataaaataga aaagagacat aaaaatgatt gacttggcaa agaaattctt
    23521 acacgaaaat atatattttg agttgtatca tcatcgagcc atttatacaa atgaagatgc
    23581 tttggtaata aagaaagaac aaggatttac aggtacagag accaaaagct tattcttaaa
    23641 agataaaaaa gataataact acgtatatct gacttttact acgaaacaaa cggatttcaa
    23701 agcattaggg aagatcgtcg gtaaaaggct ttctattgtt tcatcagaac gcatggaaga
    23761 acaaacggga caaaagcagg gcgctgtttc tccgtttggt tatgaaaaac agattccgat
    23821 tattattgat gaagagctct tatcaaatga aaaacttgtt tttgcaccag gtagaccaga
    23881 tcaaacgatg gtcatccaaa cggttgactt aaacaaaatc atccagctac ttgagatgcc
    23941 gatatttttg atgccggcaa acgaaaaaaa caattaacca agtaaaatag tgcatacttg
    24001 gaggtgaagc aacatgataa gttatccatt attagaaaga aatgcaacga ttggggttac
    24061 tgcaccatcc tcaggcgtat cagaggaaca ccattcgtta ctcgaatcag ctttaaagag
    24121 aatggaagaa aaatctttcc aagtagttac tggaaagacg ctttggacgc aagataagga
    24181 aaaatcaggt ccagcaagaa aacgagcaga tgaattcaat caaatgatgc aagatgaaaa
    24241 tatccaaatg atctttccga cttggggagg agaattattg attgagattc tcgattttgt
    24301 cgattttgat gctctacaac caaaatggat agtaggttat tcagatatta gtacgttgct
    24361 acttgctgtc acattaaaaa cagggatagc cactgcacat ggaactaacc ttattgattt
    24421 aagaggagag tacttggatg aaacgacagc aatgtgggaa agtgtactga aaacaagaga
    24481 aggagaatcg attctacagc aatcttctga aaagtatcaa aaagtgtggc cccatgagca
    24541 ttcatcatct tctgttttcc atctcactga accaacaaat tggcaatcag tcagcggaga
    24601 tgcagtaagg atgaagggac gattattagg tggttgtatt gatacgatca ggcatttaat
    24661 cggtactcct tatggagatg tccaatcttt taaaagaaag tataatgatg gaaagccgat
    24721 cttgtggttt ctagaaaact gtgagctatc gtcagttgat ttaagaagat cacttgttca
    24781 gatgaaactg gcaggctggt ttgatggcag ctcggggatc atgttcggta gaagtgcggc
    24841 agaggatttg ttagattata aaatgaagga tgtatacgaa gatctgtcaa aggaattaaa
    24901 actaccgatc ttgtatgata ttgattgtgg tcatgtaccg ccacaactga cattgattaa
    24961 tggtgcctat gcagaagtag cggtagaaga tagaaaagcg actgttttgc aaacgtttat
    25021 ttaaaaaatt ttttcctgcc ttggagtcta tcaaagacca ataaatctaa atagaaaaga
    25081 aagtgaaaga agctgacaaa atgctgtcag cttctttttg tataacatat tagaaagtct
    25141 aattatctat aactgtcaca tcgattaact gtttcacgtc attgggattt cctgtaggaa
    25201 tagctactac agatgcatta tcaatgattt cttgagttgt ttctctaatg aacgctggat
    25261 aagatgtttg atctgcaggc atttgccaat gtgaaggaac tggataacta gtgattgtcc
    25321 cgtcatggtt acttgaatac actaaaactc cctggtaact gtatttccca gtgagcataa
    25381 ccacatcttt cggatagact gcactccctg catcataagg ggcgataggt gttcctgcag
    25441 gataatgaat aacatgtaat tcgaaatcac ccgatgtatc tctaaaagta ttacctctaa
    25501 tagctagcca aacacgtgcg tactcaattt gtagatcaga atatcctgct aacggatcta
    25561 ttgactgaga agactgtgag gaggttgtgt ctattgttga agaagaaata tttgtctcaa
    25621 ctgtactact agatgtagaa gaagtattgg gctctgagac tttactgctt gttgaagatg
    25681 tattcgtttc agtagaagct gatttctgag tacttgattt ttcagctgaa ctggtttgtc
    25741 tgattgaact tttgtctgtg gtcgcagatg gatcactatt ttctttacta ggagacgtac
    25801 atcctacaag gaataaagag accaacaata aaataaaacc taactttttc atataaaata
    25861 cctcattatt tttttaatac cagtatagca taatcctgaa tttttgaatc cgtaaaacct
    25921 tgtctatgaa tataaataga gtgtatcttc tttgataaat gtcagaaaaa gtgtgacaaa
    25981 taatcatcag taaaattact tgtcacacta ttgataagga gtatttaatt gaagagaatg
    26041 attaggagaa aggatctccg tactttttat agtaatcata gaatccaagt ttgtatagac
    26101 gaatcgtttt ttctcttatt tcttctgttt caaaatggac tgcttgaaga atcaagtctg
    26161 tgaattctat aggagctgtt ccattcgcag taatcaaatt acgatctttc acagcttgtt
    26221 gttctataaa atcttcttta ttctgataat tttccgattc taaccaagga aattgcgcat
    26281 ttccggtgtg tttgtaacct tgcaataatc cgctctgagc taaataatca actgccccac
    26341 aaatagcagc tactggtacg tctgttttta acaatttatc gattatttga tataaatgat
    26401 gattttttat gtcccatgaa ttgccaccga tcataataaa aaggtcaact ttttcaggta
    26461 tttgttcgat taagtaatcg atttttgttt ttaatcctcc aatggaagtg acctctgatt
    26521 ggatagaagc agttttgttt tgccatttct cattttggtt tagtgtgcta gtaatataag
    26581 caccttccca atcggcatat tcctctaata gaaacgtaat cgcagttttc attttcaagc
    26641 tctcctttac tatctataac aaggacaaca gttttaacct acagacattc attaaaattg
    26701 ggtagcgaca gcgaaaacaa caattcttaa gttttagaca gagtatacag atagtcaact
    26761 taattaaata cgaactaaat aaaaatgaca ggtaatcatt tttgtttacc agcattataa
    26821 cattttgcat acatggatga caaaagaacc aattcccact tgcttgagta caatattaaa
    26881 agaaactgga aggcaaaaag taattataga aacgaaaaat aaatcatatc gggcactcag
    26941 acatgaaaac aaccctagag atatataact aggtaaccag tttaatgaaa gaaaaaatca
    27001 tccaagaagt cgattcttgg attttttagt ggatttgttc gccaaatacg tttagtatgc
    27061 gtatatgaga ggttgtaagc aaagcgttgt ggtctgagca cttaaggagg aatctgtgaa
    27121 aatagctttt catatttttg cagattttga cttaatgccg aaggtcagct ttgcgattac
    27181 cgtttatcga gaggctgtaa aagcaccgtg tagctccgat gacaataagc aagcattttt
    27241 agagctaggt ttccttgatt ctaaatatgc ggcttatttc aatgagttgg tgcttgaacg
    27301 cgattttaag aaggtcgaaa acaggcacga cttttcgacg taaggagaaa gaatttcaat
    27361 gatagaaaca ataaatcccg cagaaaacaa ggtttctgcg tacattcata tcccattttg
    27421 cgagcatatc tgctattact gtgattttaa taaagttttt ttagaagggc agccagtaga
    27481 tgagtatgtg gaaatgctgc tgaatgaaat gaaaataatg ctagaaagtc atccgacagc
    27541 gaatttagaa acactttacg tagggggcgg gacaccaact tctttatctg ctaaacaact
    27601 tgatcgactg ttatcaggtg ctagagagat cctgcctttt caaaatggta atgagtttac
    27661 tgtagaagcg aatccaggtg atttgacccg tgaaaaactt caagtaatga aaaactatgg
    27721 cgtcaatcgt ttatccatgg gagtgcagac atttgataat cgcttattga aaaaaattgg
    27781 acgtaaacac accgcagaag atgtgtatca aactatgcaa tttttagaag cagaaaattt
    27841 taccaatgta agcatcgatt tgatttatgc attaccggga caaacactag aaggatatct
    27901 ggatactttg gaaaaagctt tggctttgga tctgcctcac tattctttgt actcattgat
    27961 cctcgaaaac aaaacaatgt tcatgaactg ggtacgacaa ggaagactcg aactgcctga
    28021 tcaggaaacg gaaaccagaa tgtttgaaga gacgattgaa gcaatggaaa agcatggacg
    28081 tcaccaatat gaaataagta actttgggct ctccggacat gaatctcaac ataacctcat
    28141 gtactggaac aatgcccact attttgggtt tggagctggt gctagcggtt atcttggaga
    28201 tattcgttac cgcaacaaag gaccaatcca acactattta cgcccattac gagcaaatga
    28261 acgcccggta ttggaagaag aaaaattgac acgaaaaaat caaatagaag aagaaatgtt
    28321 cttaggacta agaaaaaaaa cagggattac taaaaaacat ttctatgatc gctatcaaaa
    28381 aacaattgaa tcggtgtacg gtgatgtgct aagggaatta gagcaagaag ggttacttgt
    28441 taatgaagaa gaccgtgttt atttgacacc aagagggacc tttttgggga acaatgtgtt
    28501 tgagcgcttt ttgtttgaaa aatagtttaa agaatatttg ttttttatct gaatttaaat
    28561 aaaaaaagtt caaaaataca ataaaggact attgaaacgt tgatataact ggatttacat
    28621 caattattta gaattagcac tcttgtgttt agagtgctaa aaaatggagt ctttctcttg
    28681 acaggagaag ggcttcttgc tatatttata agtggattag cacttagaat atatgagtgc
    28741 taatgagagg tgaggaagat gttaacaaag cgacaaaacg acattttacg tctgatcatc
    28801 caacactata cgagtagtgg cgtgcccgtt ggttccaaaa cattgatgtc tgagggagtc
    28861 aaggccagct cagcaacgat tcgcaatgat atgaaagcat tagaagatga aggattgctg
    28921 ttgaagactc actcttcttc tgggcggatt ccatctgctt taggctatcg ttattacgtg
    28981 gatcatttgt taaaacctgc tcgcgtagca gaagatgatt tgctgctgat tcgtcagtct
    29041 ctaggcagag aatttcatga aatcaatgag attattaagc aatctgctga gatattatct
    29101 gagctgacaa gctatacgac tttttcattg ggacctgaaa taaaagaccg ccgactgact
    29161 ggctttcgta tcgtaccctt gaataatcga cagattattg ctatcgtcgt aacagatatg
    29221 gggaatgtag aaagccaagt gttcactctt cccgaatata tgggaagtca ggaactagaa
    29281 aaaatggtac agattgtaaa cgaccgtcta gtcggagatc ctctgatgac ggtgtaccat
    29341 aaacttcgta cggagattcc gatgattctt cataaatatt tccaaacgac agaagggatg
    29401 tctcagttat ttgacaccgt tcttggtcat gtttttgaag ataaggttta tgtcagtgga
    29461 caaatgaatc tcttggatta tgagccccgt caagatcttg atcagttcaa atcgatgttt
    29521 tcttttatga aagactcaga cggacttaca caaatgatca ctccgatgga tagcaatatt
    29581 catatcaaga ttggtgctga attaggcaat gatttattgc agaatatgag tatgattcaa
    29641 gcaagttacg agatagatgg tcatggaaga ggtacaatag ccttgttagg gcctactagt
    29701 atgccttatt ctcggatgtt cggtctagtc gatgtttatc gaagagaact agcagctaaa
    29761 cttgctgatt actaccgttc gcttgacttg tcaaactcgt aatgtgaata acgaagctat
    29821 ttgcagctga tcgttctctc tttcttagta agagcaatca aacagctgac tgaataatga
    29881 aaggaagact gtatcgtgaa agaaaatcaa gaagaactag ataaagaaat gacagatgct
    29941 cagccagaac cggaaatcga tgtcgaagct gcagaagatt cgggtatttc agaagctgaa
    30001 gcggaagaat tcgaaacagc gaaattaaaa gctgagttag aagaaatgga agataaatac
    30061 ttgcgggctc gtgctgaaat cgcaaatatg gcaaatcgag gaaaaaatga gcgtgagcaa
    30121 ttacaaaaat accgttcaca agatttagcc aaaaaattac ttccatcaat tgacaacctg
    30181 gaacgtgcat tagccacaga agtgtcagat gatcaagggg caggtttgaa aaaaggcgtg
    30241 gaaatggtct tggaaagttt gcgtaacgca ctggaagaag aaggaattga aaaaatccct
    30301 gctaaaggag aagcctttga tcctaatctt catcaagcag tacaaactgt tccagcgact
    30361 gaagatacac cagccgatac gattgtagaa gtactacaag aaggctacaa attacatgat
    30421 cgcgtgttaa gaccaaccat ggtcattgtt gcacaataat tgtgcggata taaaacttac
    30481 actttcaatt aaagaaggag acgttaatta tgagtaaaat tatcggtatt gacttaggta
    30541 cgactaactc tgcagtagca gtattggaag gaaacgaagc aaaaatcatc gctaacccag
    30601 aaggaaaccg tacaacacct tctgttgtat cattcaaaaa tggagaaatc caagtagggg
    30661 aagttgcaaa acgtcaagct gtgacaaacc caaatacgat ttcatcaatc aaacgccata
    30721 tcggtgaagc aggttacaaa gtagatgtag aaggtaaatc atatacacca caagaaatct
    30781 cagcaatgat ccttcaatat atcaaaggat tcgcagaaga ctatttaggt gaaaaagtcg
    30841 aaaaagcagt tatcactgtg ccagcttact ttaatgatgc acaacgtcaa gcaacaaaag
    30901 atgctggtaa gatcgctggt ctagaagtag aacgtatcgt caatgaacca actgcagctg
    30961 ctcttgccta tggtttagat aaaacagatc gcgacgaaaa aatcttagta ttcgaccttg
    31021 gtggcggtac ttttgacgta tctatccttg aactaggaga cggtgtcttt gatgtattgt
    31081 caacagctgg cgacaaccat ctaggtgggg acgactttga taacaaaatc atcgactaca
    31141 tggtagcaga attcaaaaaa gaaaacagca ttgacttgtc tcaagacaaa atggctttac
    31201 aacgcttgaa agacgctgct gaaaaagcga aaaaagattt atctggcgta tcaagcacac
    31261 aaatcagctt gccatttatc acagcaggag aatctggacc attgcatttg gaaatgacat
    31321 tgacacgtgc aaaatttgat gaattaacag ctgacttagt agaacgtaca aaagtaccag
    31381 tacgtcaagc gctaaaagat gcaggtttat cacaatcaga aatcgacgaa gttattttag
    31441 tcggtggatc tactcgtatc cctgcagttg tagaagcagt acgtaaagaa acaggaaaag
    31501 aaccaaacaa atcagttaac cctgatgaag tagttgctat gggtgctgct atccaaggtg
    31561 gcgtgatcac tggtgatgtg aaagatgttg ttttacttga cgttacacca ttgtcattag
    31621 gtatcgaaac aatgggtgga gtgttcacta aattgattga ccgcaataca acgattccaa
    31681 caagtaaatc acaagtattc tcaactgcgg cagataatca accagcagta gacatccatg
    31741 tattacaagg tgaacgccca atggctgctg acaacaaaac tctaggaaga ttccaattga
    31801 cagatattcc agcagctcct cgtggtattc cacaaatcga agtaacattc gatattgata
    31861 aaaacgggat tgtaaatgta tctgcgaaag atctaggtac acaaaaagaa caaaaaatca
    31921 cgatcaaatc ttcttcaggt ctaacagacg aagaaatcga acgtatggta aaagatgcag
    31981 aagcaaatgc agaagcagat aaagctcgta aagaggaagt tgacctacgt aatgatgtag
    32041 atgcattgct attctctgtg gacaaaacat tgaaagaatt agaaggcaaa gtggacgaag
    32101 aagaagtgaa aaaagcagaa acagctcgcg atgaattgaa agccgctgtt gaagcaaaca
    32161 acatcgaaga aatgaaaact aaacgcgatg cattgaacga aatcgttcaa aacttgactg
    32221 ttaaactata cgaacaagcg gcacaacaac aagctcaaga aaacccagaa gcagctcaag
    32281 gcggagcaga tgatgtcgtt gatgctgatt ttgaagaagt cgatggcgac gataaataat
    32341 cagttcactg aatttcgaga gaaggccaaa gttgctactt tggctttttc ttttgaaaaa
    32401 tagtttgaag tatcggtttt tgtttcaaac aaaatatgat atgataacaa gcgacgtgaa
    32461 aatgatgaga accaatagga ggaaagccta tggcaacaaa acgtgattat tatgaagtct
    32521 tagggctctc aaaaggagca tcagaagatg aaataaagaa agcttatcgt aagctttcga
    32581 aaaaatacca tcctgacatc aataaagaac ctgatgcgga agaaaaattc aaagaagtat
    32641 cagaagcata tgagatttta agtgacccgc aaaaacgcgc tgcatatgac caatacgggc
    32701 atgcaggcac agatccaaat tacggtgctg gtggagctgg tggcggattt ggtggattcg
    32761 gcggcttctc tggtggcggc ttcggtggtt ttgaagatat cttcgactct ttctttggag
    32821 gaggcggtcg gtcagtcgat ccaaatgcgc ctcgtcaagg tgctgatttg caatatacgg
    32881 tcgacttgtc ttttgaagaa gcgatttttg gtgtagaaaa agaaatcaag tataatcggg
    32941 aagaaatctg tcatacttgt ggtgggaacg gtgcaaaacc aggcacacaa ccaactactt
    33001 gtcataaatg tcatggtgca ggtacgatta atgtagaacg ccaaacacca cttggacgag
    33061 tgatgagccg tcaaacttgt gatgtttgtc atgggacagg gaaagaaatc aaagaacctt
    33121 gtccaacctg tcatggctca ggacatgaga agaaagcaca ttcagttaaa gtgaatgtac
    33181 cagctggtgt agaagaagga caacaaatgc gtttagctgg tcaaggagaa gctggagaaa
    33241 acggcggacc atttggtgat ttgtatgtgg tcttccgtgt agaagaaagt gatatctttg
    33301 atcgtgaagg ttctgaaatt tactatgaat tgcctttaag ttttgtacaa gcagctttgg
    33361 gggatgaagt ccaagtacca actgtccatg gagatgtgaa attgaagatc cctgctggaa
    33421 cacagacagg tacgaacttc cgtttacgtg gaaaaggcgc tccgaagtta cgtggtggtg
    33481 caacaggcga ccaacatgtc aaagtaaaac tgatcacacc gaaaaatcta aatgaacaac
    33541 aaagagaagc attacgtgca ttcgctgaag ctggcggcat caaagttgaa gaacagcaag
    33601 aagacggttt cttcgataag tttaaagatg cttttggcgg gaaaaagcgg aagtagtttt
    33661 tctagtaaaa acgctaagtc attaataatt aaaaaccaga cgaacaatca tatgttcgcc
    33721 tggttttttt gtagttgtca tgtttgtacc aacaaaaaag ccagctttag aatatgataa
    33781 tcgtcatagt ttctaggggt ataaccagtg agagaatgga acttgttcaa tcgatattgc
    33841 aaggtgtttt tatgaataaa taattcttct gagcaatttt tgatgcttcc gttattttta
    33901 ctgaagcatg ccaaagtctt cttgaacaaa tgtacttctt cttctgtcag gcttttcaaa
    33961 atacgtttta catataatgt tcgttgatct gacgggattg ctggtaaaac gatcccgagg
    34021 tctaaatctt caaaaaagcg gatctcgttc acagattgat ggaaagctat ccattcgcaa
    34081 acttgtttgg catgaaggaa agattgcggt gtctcttgct ctgtataaca aagcgaccca
    34141 attccaaagt ttagctgtaa ctgatacatt ttattaaact ttgtctggat tttatcaagc
    34201 aatgatagca atgaggctct ggaaatccga ttgactagga taatgatttg ttgtctatgt
    34261 acagtgagca aagcctgtcc gtaataagag aagacccttt cgagcaactc caataaagga
    34321 ttgatccgtt cttgacacaa ttgctgattg tcagaaagtt gtcccacaac tacataatat
    34381 ggagaagaaa aatcaagctc aattaagtga gggtggtatc gactatgtac ttgatatcat
    34441 caatgaaccg atggtacttt cttatgcgat ggaacaggta gagcgattgc ttgtttgtgc
    34501 aggaaaacaa gcgatgcggc tgatacgatt aggtgagaaa ataagaagat aaaaatacac
    34561 ggtcccttca tggcgaccgt gcatttttgg tttttattaa atatttaata ctttattcaa
    34621 gaaatctttt gtccgttcat tttgcggatt ttcaaagatt tgttgaggcg ttccatcttc
    34681 taaaaagttt ccgtcgtcaa tgaacatgac gcgattggcc acttctttag cgaaccccat
    34741 ttcgtgcgta acgataacca tcgtcatacc ttgttctgct aactttttca tgacgttcaa
    34801 gacatcaccg accatttcag gatcgagtgc agaagtaggc tcatcaaaaa gcatgatgtc
    34861 agggttcatc gctagagcac gagcaatagc cacacgctgt ttttgtccac cagaaagcat
    34921 ttcaggatac atatcttttt tatcttctag accaactgtc tgcagtaatt tgattgcttt
    34981 tttctctgct tcttctctag attctttctt caggtccatc ggtgctaaaa tgatgttttc
    35041 caaaatagaa agatgaggga ataggttaaa gtgttggaat accattccga tatgttgtct
    35101 caccaagttg atatctgtgc ttttatccat caagtgggcg ccgtcaataa taatttcacc
    35161 gtcagaaggt tcttctaaac gattcaagca acgcaagaat gtactttttc ctgaacctga
    35221 agggccaatg atacagacga catctccttc gttgatggat acattgatgt cgtttaatac
    35281 tgtgttatcg ccgtattttt tgactaaatg ctcaactaag attttttctg ccatcttact
    35341 tcaccttctt ttctaaaact tttgctaatt ttgtcaatgc tgtgatcaaa atcaagtaca
    35401 tgatcgcaat gatcaagtaa acatacgtac tttgtgttgt acgtgcaaca atgatcttac
    35461 cagtttgcag caattcgact acaccgattg cggaaatgat cgttgtgtct tttaatgaga
    35521 taacgaactg attgacgaat gatgggatca tgatgcgtat cgcttgcggc aaaatgattt
    35581 tttgcattgt ccgattataa gaaagaccta aacttctgga agcttccatt tgtccgacag
    35641 gaacggcgtt gatcccgcct cgaacaatct ctgcgatata agcacttgcg ttaagagtca
    35701 aggtgataac accagcaagg aagtcaggaa tcgtaaatcc aacgatacca ggcaacccaa
    35761 agaaaataaa gaacgcaaga accatcattg gaattcctcg gatgatatcg acataaatac
    35821 tagcaattgt gcgaagagcg cgtattggtg ctacactgaa taatccaaaa atcacaccga
    35881 ttactatagc caaagcaaag gagatcaaag ttaggagaat tgttctccaa agtcctttca
    35941 acaatgcttg atagttgttt tggataagtc caagaaatgt tgattcatca gcagtggaag
    36001 actcactgga agtttctgaa ccatccgcta catattcttt aataatctta tcgtattcgc
    36061 ctgttctttt taattctttc aatccttcat tgaacatatt aagaagctca ggattttgtc
    36121 cttttttaac ggcaaatgca tattttccgc cagattcttt tttgatcggt gtttccaatt
    36181 cttgtccttg tttgatcgca taaccgatta ccggataatc atccatcatt gcatcgattg
    36241 cgccaacttt taacccgtcg tacaattgat cagcagcatc aaaatatttg atagaatagc
    36301 catattcaga ttcatggtcg cttaaaaatt cagcactttc ggtaccaact tttgctccga
    36361 ctgtttttcc tttcaaatct tcataagact tgatcgaagt atctcctttt ttgacagcta
    36421 attggatccc gctatcaaag taagaatcag aaaaatcata gcttttcttt cgttcatctg
    36481 ttacagtcat tccggcaatc attccgtctg cttgtcctga ttccaaagct tgcaaagcag
    36541 cagagaaacc acggtagtcc attcggatgt taaatccttg cagtttggcg atgttttcca
    36601 tcaattttac atcgatgcct tcgtactcgc cctttgcgtt ttgaaattca aatggagcaa
    36661 aagcagagtc actggcaatt acgtatacgt cttttttggg ctctattttt tgcattgtct
    36721 cgcttgtgct tgactctgcc gttgtagtgt tgtcagcttg tgcaacatga ccaaacgcaa
    36781 gtgtcacaag tcctgtcatt aagaaaacaa atgagtgaaa taaatgcttt cttttcataa
    36841 tcaacctcct aaatttccaa tattttatta ttataggcga aaagtgctga atcagacaag
    36901 actgtaagct cgaaaaaatg aaaaaaatgc gagtttctaa cattttatgt tataaaacat
    36961 aacatgtata ataagataaa aaagtggcga aagtatgttc ggtgtggtat aattttttag
    37021 taaggaatgc ctttgctttc cttttctttt tattggtcgt aaaatgaaaa ggaatgaatg
    37081 aaaaggagga cgaagaatga ttgagagaga tacctcccga cactttgagc ttgtctcgaa
    37141 ataccaaccg gctggtgatc agcctgaagc gattaaccaa ttagtggatg gcgtagtcgg
    37201 cgggaaaaaa gcacaaatct tattaggtgc gactggaaca gggaaaacat atacgatttc
    37261 caatcttatt gagaaagtga ataaaccaac actgattatt gcccataaca aaacattggc
    37321 tggtcagctg tacggggaat tcaaggaatt tttccctaac aatgctgttg aatattttgt
    37381 ttcttattat gattattatc agcctgaagc ttatgtgcct tcaagcgata cgtatatcga
    37441 aaaagattca agtgtaaatg atgagatcga caaattacga cattcggcta ctagttcatt
    37501 attagaaaga aatgatgtga tcgtcattgc atccgtttca tgtatttttg gattaggctc
    37561 gccttttgag taccaaaaac aagtagtttc gattcgacag ggagcagaac tagatcgcaa
    37621 tcagttgatt cgtgacttag tcagtatcca attcgaaaga aatgatatag attttcagcg
    37681 cggtcgtttt cgagtgcgcg gtgatgtcgt ggagattttt ccggcttcaa gagatgaacg
    37741 tgccttacgt gtggagtttt ttggagatga ggtcgaacgt atccgagaag tcaatgcact
    37801 gacaggtgaa gttttaggag aaacggaaca cgtagcaatc ttcccggcga ctcactttgt
    37861 gacgaatgat gaacatatgg agcatgccgt agcgaatatc aaagcggaat tagaacagcg
    37921 tttaactgtc ttgcgaaatg aaaacaaact tctggaagct caacgtttag aacagcgaac
    37981 caattacgat attgaaatga tgttagaaat gggctacacg tcgggaattg aaaattattc
    38041 tcggcatatg gacggacgta aagaaggtga accgccttat acgctattgg atttctttcc
    38101 tgaagatttt ttgatcgtgg cggacgaatc gcacgtaacc atgcctcaaa tcagaggaat
    38161 gtataatggt gaccgagcga gaaaacagat gctagtagat tacggtttcc gtttgccatc
    38221 tgctttagac aatcggccac ttcggttaga agagtttgaa aaacatgtca atcagatcat
    38281 ttatgtctct gcgacgccag gaccatatga acatgaacaa acagataccg ttatccaaca
    38341 aatcatccgt ccgacagggc tgcttgaccc agtgatcgaa gttcgtccaa tcatgggaca
    38401 aatcgatgat ctagtaggcg aaataaatga acgagtcgaa aaagaccagc gggtgtttgt
    38461 aacgacattg acgaaaaaaa tggcagaaga cctcacagat tatttcaaag aattagggat
    38521 caaagtcaaa tatttgcata gtgatatcaa aacgctggaa cgaacagaaa tcattcgaga
    38581 tcttcgatta ggtgaatttg atgtgttagt tggaatcaat ttgcttcgtg aaggattaga
    38641 cgtacctgaa gtttcccttg ttgctatctt ggatgcggat aaagaaggct ttttacgtag
    38701 tgaacgttcc ttagtccaaa cgattggacg agctgctcgg aatgaagaag gtaaagtaat
    38761 catgtacgca gacaaagtaa cagattctat gcgtctagcg atggatgaaa cgtcaagacg
    38821 tcgtacgatt cagcagaagt acaatgaaga acatgggatc gttccaaaaa cgatcattaa
    38881 agaaatccga gatttgattt ctattacgaa agaatcggaa gatgatacaa aagaagcggt
    38941 acaagtctcg tacgaagaaa tgacgaagga agaaaaagac acgttattga tgaaattaga
    39001 aaaagaaatg aaagatgcgg caaaagcttt ggattttgaa acagccgcga atgtgcgaga
    39061 tatgatttta gaattaaaag cttcaaagta ggaggacaac atggctaacg ataaaattac
    39121 gattcatggt gcacgtgccc ataacttgaa aaatatagat gtaacgattc cacgagataa
    39181 attcgtggtc gttacaggtt tgtccggttc tggaaaaagt tccctagcat ttgatacgct
    39241 gtacgctgaa gggcagcgga gatacgtaga gagcctttct gcttatgctc gtcagttttt
    39301 aggacaaatg gataagccgg acgtagatag catcgacgga ttgagtccgg cgatttctat
    39361 tgatcagaaa acaacaagta aaaatcctcg gtcgacagta ggtactgtga cggaaatcaa
    39421 tgactattta cgcttgttgt ttgcacgtgt aggacatccg atttgtccca acgatcatat
    39481 cgagattacc agtcaatcag tagatcaaat ggcagatcaa gtaatggctt tgcctgagcg
    39541 cacaaagatc caagtgttgg caccgatcgt ggtaaagaaa aaaggacaac ataaaaaaat
    39601 attcgaacga atccaaaaag agggatacgt ccgcgttcga gtcgatggtg agatctatga
    39661 tttaagtgaa gtgcctgagc tggagaaaaa caaaaaacat gatatcgcga tcgtcatcga
    39721 ccggatcatt gtgaaagaag ggattcgttc tcgcctattt gattctttag aggcggccct
    39781 gcgattagca gacggctatg ctctggttga cgtgatcggt gaagaagaaa tgttgtttag
    39841 cgaacactat gcctgtcctt attgcggatt tactgttggc gaactagaac caagactgtt
    39901 ctcattcaat gcgccttttg gagcttgtcc agactgtgat ggtttaggtg tcaaattaga
    39961 agtcgatcaa gatttagtga ttccagatag aacgaagaca cttagtcaag gtgctatcgt
    40021 tccatggaat ccaatcagct ctcagtatta tcctcaaatg ttagcgcagg cttgtgaaag
    40081 tttcggtatc gatttagata caccattcga agaattaccg gaagagcatc aggagatcat
    40141 cttgaatggg acagatgatc ttttccattt ccattatgaa aatgattttg gtggcgttcg
    40201 cgatgtagaa acgactttcg aaggggtatt gaagaatatc gagcgtcgtt atcatgatac
    40261 gaacagtgat ttcacgcgtg agcaaatgcg tctttatatg acagaattaa cttgtcagac
    40321 atgtaaaggt tatcgattga atccccaagc tctatctgtt caaatcaatg gaacgaatat
    40381 cgggcaaaca aatgagttgt ctattcaaaa agcagtagat ttcttctcaa acttaacgtt
    40441 atctgaacaa gagaaagtaa ttgccaaacc gattttaaaa gaagtaaatg acagactttc
    40501 attcttggaa aatgtgggac tagactatct aactttgagt cgcgcttccg gaacattatc
    40561 tgggggagaa gcgcagcgaa tcagattggc tacacaaatt ggatcgaatc tttctggagt
    40621 tttgtatatt ttagatgaac catcgatcgg attgcatcaa cgcgacaacg atcgactgat
    40681 tggctcatta aagaaaatgc gtgatcttgg caacaccctc gttgtagtcg aacatgatga
    40741 agatacgatg tgggcagcag attatttgat tgacgtcgga cctggggccg gagaacaagg
    40801 cggacaaatc gtggctgcag gcactcctga agaagtagct aatgatgaaa attctttgac
    40861 agggaaatat ctttcaggga aaaaatcaat ccctgtacca aaagaacgcc gtaaaggtaa
    40921 tgggaaagca atcaagatca ctggtgcttc agaaaacaat ctgaaaaata ttagtgttga
    40981 atttccatta ggagaatttg tagcagtcac aggtgtgtct ggttctggaa agagtacatt
    41041 ggtcaatagt atcttaaaga aatcgttagc gcaaaaatta aataagaatt ctgctaagcc
    41101 aggtaaattc aagacaattt ccggctacga aagtatcgaa aagatcatcg atatcgatca
    41161 aagcccaatc ggccggacgc cgagaagtaa tccagcgact tatacaagtg tatttgatga
    41221 tatccgtggg ttatttgctc aaacgaacga ggcaaaaatg cggggttata agaaagggcg
    41281 ttttagtttc aacgtaaaag gcggtcgttg tgaagcttgt cgcggggatg gaattattaa
    41341 gatcgaaatg cactttttgc ctgatgtcta tgttccttgt gaagtatgtc atggtaaacg
    41401 atataattct gaaacattag aagtgcatta caaaggaaaa agcattgctg atattttgga
    41461 aatgacagta gaggatgctg tagaattctt caagcacatt ccaaagattc atcgcaaact
    41521 gcaaacgatt gttgatgttg gcttaggtta tgtgacgatg gggcaaccag caacgacatt
    41581 gtccggtggt gaggcacaac ggatgaaact tgccagtgaa ttgcacaaaa tctctaatgg
    41641 aaagaatttc tatatactag atgaaccaac gacaggactt catagcgatg acatcgcccg
    41701 cttgttgcat gtattacaaa gattagtaga tgctggtaac acagttttag tgattgaaca
    41761 caatctagat gtaatcaaaa cagcagatta tatcattgat ttaggaccag aaggtggaga
    41821 aggtggagga acgatccttg cgactggaac accagaagaa atcattaacg taaaagaaag
    41881 ttatacaggt cactatttga aaaaaataat ggtataaaga ggatagatag ctgagatagt
    41941 taaaaaaaca taaaaaaatg aatttttgct tgttttatta atatcagtgt tctagaatca
    42001 ttacatggta gttctttcta cactgattgg tatagataaa aacttcctat aagttcaatc
    42061 cgttcaaaaa agaattgagc aatcggagga ctttcctttg attgcttttt tctttatggt
    42121 atgatattcc ttgtgtagtt ggaaaagaaa aacaagagat tatgagtaag tgagagataa
    42181 tgatgaacag tattgaaaat gaagaattta tccctatatt attaggaagc gacatgaacg
    42241 tttatggtat ggcacgttct tttaatgaag catacggcaa aatctgccaa gcatatgctt
    42301 cggatcagtt agcccctacc cgctacagta aaattgtcaa tgtagaagtt attccaggat
    42361 ttgataaaga ccctgtattt atcgagacga tgcttcgttt ggcaaaagaa agatattctg
    42421 ataagagtaa aaaatatctt ttgattgctt gtggtgatgg atatgcagaa ttgatctccc
    42481 aacataaaca agagctgtca gaatatttta tctgtccata tattgattat tctttatttg
    42541 aaaggctgat caataaagta agcttttatg aagtttgtga agaatatgat cttccgtatc
    42601 ctaaaacatt gatcgtcaga gaagaaatgt tagtaaatgg acatttggaa caggaattgc
    42661 cttttgaatt cccagttgct ttgaaacctg caaacagtgt ggagtatctt tctgtccaat
    42721 ttgaaggaag aaaaaaagct tttattttag agactagaga agagttcgat ttaattttag
    42781 gccggatata cgaagccggt tataaaagtg aaatgattgt acaagatttt atcccgggtg
    42841 atgatagtaa tatgcgtgtg ctaaatgcgt atgtagatga agatcatcaa gttcggatga
    42901 tgtgccttgg tcatccacta ttagaagatc ctacaccagc atcgattggt aattacgttg
    42961 tgatcatgcc agattataac gaaaaaatct atcaaaccat taaggcattt ttggaaaaaa
    43021 tcgaatatac aggctttgcc aatttcgata tgaagtatga tcctagagat ggagaatata
    43081 aattatttga aatcaatttg agacaaggtc gtagcagttt ctttgtgaca ttgaacggct
    43141 tgaatctggc tcgttttgtc acagaagatc gagtgttcaa caaacccttt gttgaaacga
    43201 cctatggaac gaatcaatca gataaagcaa gattatggat gggtgtgccc aaaaaaatct
    43261 ttttagaata tgctcgggaa aatgaagaca aaaaactagc tgagcaaatg atcaaagaaa
    43321 atcgttacgg tactactgta ttttatgaaa aagaccgatc aatcaagcgc tggttgttga
    43381 tgaaatatat gttccataac tatattccaa gattcaaaaa gtattttcat gtgaaagaag
    43441 gctagttcat ggagaatttt ttcagtattt taggcggaat gggcacgatg gcgacagaaa
    43501 gttttgttcg cttgatcaac caccgaacga aagctacaaa agatcaagaa tatttgaatt
    43561 atgtcttatt caatcatgca acagttcctg atcgtacagc ttatatttta gatcgatcag
    43621 aagaaaatcc aatgccgttt ctgctggatg atattgagaa acaaaattta ttgcgaccaa
    43681 acttcattgt gttgacttgt aacaccgcac actacttttt tgaagagtta caagcggcaa
    43741 cggatattcc tatcttgcat atgccaagag aagcagcaaa tgaacttgtc cgtcagcata
    43801 cgacagggag agtagcgatt ctaggaacag aaggaagtat gaaagctgga atctatgaac
    43861 gcgaagtcaa aaatcttggt ttcgaaacag tgattcctga tactgcgctt caagaaaaaa
    43921 tcaattacct gatctatcat gagatcaagg aatcggatta tttgaatcaa gagctctatt
    43981 acgaaatctt agaggaagcg gtagagcgcc taaactgtga aaaagtcatc ctaggttgca
    44041 cagaattatc tttgatgcat gaatttgctg aagataatca ttacccagtg atcgatgctc
    44101 aatctatttt agcggatcga acgatcgaac gtgcattagc tgaaagaagc gaggcattgg
    44161 atacagcatc ggaaaagtaa aaaaattgga tttggggcaa atatcctaaa agatatttgg
    44221 tccaaatctt tttgtaaaag aaaaagaaaa ctggtaatga tacgcccggg atgatataat
    44281 tttattatgc acaatgtgag aggggttcgt aaatatgaca gataatttgc aattagtcat
    44341 cataacaggt atgagtggtg cagggaaaac agtagctatc caaagttttg aagatatggg
    44401 ctatttttgt atcgataata tgccgcctcg attgattcca aaattctggg aattgatcaa
    44461 agaatcaggt aaagtcacaa aaatggcttt aggagtggat ttgcgttctc gttccttctt
    44521 tgaagaaatc caaaacatgc tgatcgaaat cgaaaatacg aacttcatcg acacttctat
    44581 cttattttta gatgcttcag acgaagaact agtggctcgc tacaaagaaa caagacgagc
    44641 acatccaatg gcgatggacg gtttgatcac tgaagggata cgtaaagaac gggcgatact
    44701 agacgacttg aaagcccaag cttccgtgat cattgatacg acaacattga caccacgaca
    44761 attacgtgaa aaaatcaatg agtcattcaa atcaaaggga gaccaaggat ttcggatcga
    44821 atttgtatca tttggtttta aatacgggtt gccgatcgat tcggatattg tgatggatgt
    44881 gcgttttttg cccaaccctc attatatccc ggaactaaga ccattgaccg gaaaagatca
    44941 gccagtctat gattatgtga tgtcctttga tgaaacgcaa tcattctacc ataaattttt
    45001 ggatcttctg gaaactgtat tgcctggata cattaaagaa ggaaaaagca gcttgacagt
    45061 tgcaatcggc tgtacaggcg gtcaacaccg ttctgtggca ttgactgaac gtttggcaaa
    45121 tgctttaggg aaaaactata aagtcaatgt gacacatcgg gacaaggata aaaggaaaga
    45181 gacggtgaac cggtcgtgaa aatgaaaacc taccggataa gaaaaccaaa gatcgtagtg
    45241 gtcggcggtg gcactggtct gccagttatc ctgaaaagtt tacgaaatca aggagcagat
    45301 atcacagcag tagtgactgt tgcagatgat ggtggaagca gcggtgcaat cagagaatcg
    45361 atcgctatgg ctcctcctgg tgacttgaga aatgtcttag tggcgttatc ggatatgcca
    45421 caattctatg aagatatttt ccaataccgt ttcaaaaagg aagatcagtt tttagccaat
    45481 catacgatcg gtaatctgat cattgccgca gtttccgaga tgcggggaag cacttatgag
    45541 gcgattcaat tattagcaaa aatgatgcat gtagatggac atgtttatcc ttcttcagaa
    45601 actcctttga ccttgcatgc tgtttttaaa gacggaacga ctgcagtagg agaatctaaa
    45661 atcgcgatca accgtaaaac cattgaccgt gtgtatgtct gcaacacaaa tgataaaagt
    45721 gaagccaaag cggctcgaaa agtcgtttca gcaattatgg acgccgacat ggtcgttttg
    45781 ggacccggaa gtttattcac cagtatcctt ccaaatttag tgataccaga aatcggcgaa
    45841 gcaatgctca agacaactgc tgaaaccgtc tatatctgta atatcatgac ccaaaaaggg
    45901 gaaacggaac atttcacaga tgccgatcat atacgtgttt tacacaagca tttgaatcag
    45961 ccttttatcg atacagtatt ggtcaatacg gaaaaagtgc ctgaagatta tatggaccca
    46021 gagatctatg atgagtatct agtacaagtc gcacacgact tcaacggatt gagaaatgaa
    46081 ggatgtcgag tgatttccac cgacttttta gaattgaaag atggtggtgt cttccacgat
    46141 ggagacaaag tagtagaaga attgttccgt ttagttttcg gttcaaaata ttaagcaatt
    46201 tattgttgga gaaaggagga gaataggatg tcatttgctg cagatgtgaa gaaagaacta
    46261 actggtttgg aagttcatcg agaacatgcg aaagcggaat tagctgcttt gctgcgaatg
    46321 aacggctctt taggtattgt gaaccagcag tttattttga acgtccaaac agaaaatgct
    46381 gcaattgcca gacgtatcta ttctcttttg aaagatcatt atcaggtacg aagtgagcta
    46441 ctcgttcgta aaaaaatgaa attaaaaaag aacaatgtct atatcgtccg gttgaagcaa
    46501 ggcacaaaag atgtgttgat ggatcttgat atcatggatg gtatgatgtt caatggacac
    46561 gtttcggacg agattatggg aaattcgcaa aaaatgcgtt cttacttacg tggtgctttt
    46621 atggcctcag gttcagtcaa taatccggaa acgagtcgtt atcatttgga aatattttct
    46681 atttatgaac agcataacca agacatttgc gatatgttaa attattacgg tctacatgct
    46741 cgaacgcttg aacggcgcaa tggctatatt tcgtatttaa aaggagcaga aaaaattgct
    46801 gatttcttaa cattgattgg tgcaaccaac tcaatgctcc gatttgaaga tgttcgaatc
    46861 gtacgggata tgagaaattc ggtcaatcgt ctagtcaatt gtgagacagc aaatctgaac
    46921 aagacgattg atgcggcttc taaacaaatc gaaaacatcg aattgatcga agcaaaggtc
    46981 ggtctacatg cccttcctga aaaacttcag gaaatcgcag aacttcggct tcaacatcca
    47041 gaggtcagct tgaaagaatt aggggaaatg attccctcag gtgcaatatc aaaatcggga
    47101 attaatcacc gaattcgcaa aataaatgaa tttgcggaaa aactgcgtga agaagcagtt
    47161 taatccaaag aaaaaactga tacatgaagc aggagatgcg aatgtatcag ttttttttaa
    47221 aagctatact tgcttttctt ccgtcaaact ataattccaa ctttactgga gtaacataat
    47281 gttgaaaggc ttctattgtt ttttaataca atcgtataaa aagcggggag acaactgaat
    47341 gaagatttta gttttataca taaacttttg cttaatatag aagtcctgat atagatagga
    47401 tcaagtattt atctataact ggagattaat taaaaactgg aaggaactgc tcgatcaacc
    47461 ttgagaactg tttttcttac ttctggtcaa gattctcgtg gttggtggat aaggatggtt
    47521 gataagttca ttggattagc tagtcgaaaa caaccaggtg taattaatgt agaagtttta
    47581 acaaggggat ggagtgattt attcagtgat aatcataagt tcataaatag taattgggat
    47641 gtatggttgg tatacgttat acctgaactt gaactatcaa gatttggttt agaatttgag
    47701 aatcgatgtt tataaaggga gggcaaaaaa tgtgcttttt tacaactttt actatcatta
    47761 tgattgcagt actttttatt tttctagata tagcaaagcg aaatacagca tttttattat
    47821 atcgggtttt acttcgagca ggtctcataa catttatatc gatcgttgga ttttttctat
    47881 tcacagttat tgtatttatt tggagaacta cagcaccacc attgccagag attacatatg
    47941 gagaatttcc gtttagtctt gaatatgaaa tagatgagga aagaattttg attgaagata
    48001 cggtgattgc agaatttata ggaagtttta gagggaatgt gacaactcaa cctagacgaa
    48061 gttggagtat aaaactttta aataatagtg gagagttgaa agcatttcat tatgaattct
    48121 taataataga aagtgaagat gtaacaatca ctttaagtag tggctctgct ggatatttta
    48181 tgaatgatgg tggaagcaag ccacagctca cagtccgtga tcgtattgca ggttttatgc
    48241 atttttctca ctatgactta gaagaagctc gtaaaatact tgcagaatat gggatcacat
    48301 taatcaattg ggaatatgcg ccaccgataa gaaatttttt caatgattat tattagtctt
    48361 ataaaaaaca gaatgtaaaa tttatgtgcg cgagtattta gttttccatt ttttgtttga
    48421 tagatatata gcattgttga agcatgggat agtggtgcca attttatcaa tgaggttggt
    48481 caggcagtta acataattgg tgatgctata aatccattta attggaattg gaggaattag
    48541 gtgtggaaac agtgagatta tggatattca tgaaaaattt tcgttcggct ttgagatatg
    48601 ttattctgga atcaaaatca ggttattatc tgattgacac agatcactat actttttggg
    48661 gaggctacct ttttccgatt tttaattgga taatccccca taaggttatg aaaattaact
    48721 tgcctgcaga agaaataaat agattaatac tcaacaaaga tttacaaagg aaaagagaga
    48781 aagaacattc taatgttgct tggataggtc cagcatttgc agtagtgact tcttcaattg
    48841 tcggtcctat gctagagagt atttatagtg atttttctat tggaatacgt tatttatttg
    48901 ttactttaag tatagctgtt cttttgtgca taaagggtta tgttagcaag aagaataaag
    48961 atattttaac actaatcggt gtaaacaatt tatctagtac taaaattata ctgtttcctg
    49021 aatctataaa agaaggatca aggttgttga taatttttat aatgcttata ctgttttctg
    49081 ttttatttgg ggtgatgttt atag
//
LOCUS       DACCVZ010000011        48882 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.011, whole genome shotgun sequence.
ACCESSION   DACCVZ010000011 DACCVZ010000000
VERSION     DACCVZ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.011"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(324..1106)
                     /locus_tag="IVW63_000628"
     CDS             complement(324..1106)
                     /locus_tag="IVW63_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858928.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(1171..2007)
                     /locus_tag="IVW63_000629"
     CDS             complement(1171..2007)
                     /locus_tag="IVW63_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7858929.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(2025..3434)
                     /locus_tag="IVW63_000630"
     CDS             complement(2025..3434)
                     /locus_tag="IVW63_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP7858930.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(3448..5271)
                     /locus_tag="IVW63_000631"
     CDS             complement(3448..5271)
                     /locus_tag="IVW63_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7858931.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(6114..6440)
                     /locus_tag="IVW63_000632"
     CDS             complement(6114..6440)
                     /locus_tag="IVW63_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858932.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(6486..6848)
                     /locus_tag="IVW63_000633"
     CDS             complement(6486..6848)
                     /locus_tag="IVW63_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HAP7858933.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(6885..7099)
                     /locus_tag="IVW63_000634"
                     /pseudo
     CDS             complement(6885..7099)
                     /locus_tag="IVW63_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7227..7562
                     /locus_tag="IVW63_000635"
     CDS             7227..7562
                     /locus_tag="IVW63_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7858934.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(7638..9635)
                     /locus_tag="IVW63_000636"
     CDS             complement(7638..9635)
                     /locus_tag="IVW63_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858935.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(9733..10008)
                     /locus_tag="IVW63_000637"
     CDS             complement(9733..10008)
                     /locus_tag="IVW63_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7858936.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            10240..10974
                     /locus_tag="IVW63_000638"
     CDS             10240..10974
                     /locus_tag="IVW63_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7858937.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            11013..12155
                     /locus_tag="IVW63_000639"
     CDS             11013..12155
                     /locus_tag="IVW63_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7858938.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(12250..13641)
                     /gene="sufB"
                     /locus_tag="IVW63_000640"
     CDS             complement(12250..13641)
                     /gene="sufB"
                     /locus_tag="IVW63_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAP7858939.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(13646..14116)
                     /locus_tag="IVW63_000641"
     CDS             complement(13646..14116)
                     /locus_tag="IVW63_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HAP7858940.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(14103..15338)
                     /locus_tag="IVW63_000642"
     CDS             complement(14103..15338)
                     /locus_tag="IVW63_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP7858941.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(15335..16621)
                     /gene="sufD"
                     /locus_tag="IVW63_000643"
     CDS             complement(15335..16621)
                     /gene="sufD"
                     /locus_tag="IVW63_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAP7858942.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(16634..17407)
                     /gene="sufC"
                     /locus_tag="IVW63_000644"
     CDS             complement(16634..17407)
                     /gene="sufC"
                     /locus_tag="IVW63_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAP7858943.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(17604..18452)
                     /locus_tag="IVW63_000645"
     CDS             complement(17604..18452)
                     /locus_tag="IVW63_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7858944.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(18476..19162)
                     /locus_tag="IVW63_000646"
     CDS             complement(18476..19162)
                     /locus_tag="IVW63_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7858945.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(19155..20189)
                     /locus_tag="IVW63_000647"
     CDS             complement(19155..20189)
                     /locus_tag="IVW63_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7858946.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            complement(20584..20922)
                     /locus_tag="IVW63_000648"
     CDS             complement(20584..20922)
                     /locus_tag="IVW63_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HAP7858947.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(20924..21280)
                     /locus_tag="IVW63_000649"
     CDS             complement(20924..21280)
                     /locus_tag="IVW63_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAP7858948.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(21286..22473)
                     /locus_tag="IVW63_000650"
     CDS             complement(21286..22473)
                     /locus_tag="IVW63_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP7858949.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(22664..23509)
                     /locus_tag="IVW63_000651"
     CDS             complement(22664..23509)
                     /locus_tag="IVW63_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP7858950.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     HLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTKRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            23743..24708
                     /locus_tag="IVW63_000652"
     CDS             23743..24708
                     /locus_tag="IVW63_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAP7858951.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            25085..26128
                     /locus_tag="IVW63_000653"
     CDS             25085..26128
                     /locus_tag="IVW63_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAP7858952.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(26190..26654)
                     /locus_tag="IVW63_000654"
     CDS             complement(26190..26654)
                     /locus_tag="IVW63_000654"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAP7858953.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            26900..27847
                     /locus_tag="IVW63_000655"
     CDS             26900..27847
                     /locus_tag="IVW63_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP7858954.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(28058..30130)
                     /locus_tag="IVW63_000656"
     CDS             complement(28058..30130)
                     /locus_tag="IVW63_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP7858955.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(30063..30440)
                     /locus_tag="IVW63_000657"
     CDS             complement(30063..30440)
                     /locus_tag="IVW63_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HAP7858956.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(30569..31129)
                     /locus_tag="IVW63_000658"
     CDS             complement(30569..31129)
                     /locus_tag="IVW63_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7858957.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            31279..32571
                     /locus_tag="IVW63_000659"
     CDS             31279..32571
                     /locus_tag="IVW63_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP7858958.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(32631..33749)
                     /locus_tag="IVW63_000660"
     CDS             complement(32631..33749)
                     /locus_tag="IVW63_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAP7858959.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(33763..35184)
                     /gene="arcD"
                     /locus_tag="IVW63_000661"
     CDS             complement(33763..35184)
                     /gene="arcD"
                     /locus_tag="IVW63_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HAP7858960.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(35430..36551)
                     /gene="mnmA"
                     /locus_tag="IVW63_000662"
     CDS             complement(35430..36551)
                     /gene="mnmA"
                     /locus_tag="IVW63_000662"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAP7858961.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            36955..37554
                     /locus_tag="IVW63_000663"
     CDS             36955..37554
                     /locus_tag="IVW63_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAP7858962.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(37692..38978)
                     /gene="efmA"
                     /locus_tag="IVW63_000664"
     CDS             complement(37692..38978)
                     /gene="efmA"
                     /locus_tag="IVW63_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HAP7858963.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(39249..39593)
                     /locus_tag="IVW63_000665"
     CDS             complement(39249..39593)
                     /locus_tag="IVW63_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HAP7858964.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(39730..40866)
                     /locus_tag="IVW63_000666"
     CDS             complement(39730..40866)
                     /locus_tag="IVW63_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP7858965.1"
                     /translation="MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAH
                     EKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIEHPA
                     VLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK
                     EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV
                     NIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLILDTL
                     EANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNIEPS
                     HVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(41055..42029)
                     /locus_tag="IVW63_000667"
     CDS             complement(41055..42029)
                     /locus_tag="IVW63_000667"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAP7858966.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(42109..42984)
                     /locus_tag="IVW63_000668"
     CDS             complement(42109..42984)
                     /locus_tag="IVW63_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HAP7858967.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            43114..45021
                     /locus_tag="IVW63_000669"
     CDS             43114..45021
                     /locus_tag="IVW63_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HAP7858968.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(45562..48840)
                     /locus_tag="IVW63_000670"
     CDS             complement(45562..48840)
                     /locus_tag="IVW63_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HAP7858969.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
BASE COUNT        14011 a        10293 c         8637 g        15941 t
ORIGIN      
        1 gttatcttta gaaccatttc agatacatat gaaacaatta catatgattt tttcataaaa
       61 aaacagtact gtctagtagt ataaaatata caaatttctt aaaaattttt tcactaaaat
      121 cactacctga aacagtctaa aacacttata tatcaacgtt taatgaaact atctccgttt
      181 catttcagat acaaataaat atagtcgggc tccaaatccg aaaaaaaata cccccagtag
      241 cttatcctaa gctactggag atgtataagt acggtcatat aacaacgggg tagggtaaat
      301 aaatgaaaaa gatggaagaa tcattattca ataacttttt taaatacttc gttgtaatca
      361 gttacctgtc cgttcttaaa taccacagaa taatcttttt tcccattttc aagtaaccga
      421 agtggaatgt ctttaccaac ttgctctgtc actgcattac tgatacctgt tagattagct
      481 aataaatctg ataaagattg agcatctgta gaaatctctg tatcagtatt tatcgtgatt
      541 cctttatctt catttacaag cttccaagta ggtggtatag ctgtgtatgt ttcgatgaat
      601 gaatcaattc tttcatctat cgtcttccca gtatctactt ctgtctcatt actcttagat
      661 gaatcgattc tttcatccat cgtctgctcc gtaactgctt ctgtctcatt attctcaccg
      721 gaaactctct tcacacccaa acttatatat tgtccatctt tagtgtgcat agttaaaatt
      781 cccacgcttt tactaataaa ttcactataa ccagttcttt caatagagac ttcaatgtat
      841 ttcacactat catactcaaa agaaaaatag acatgtaaaa gcattttgtt gtttacatct
      901 acataataat cctttgactc tacttgagac cttcctatac ggaatacagc tttactgtct
      961 gatatctcta taccagcatc cttattatta atctgccaat ctccaagtag ctcttctggc
     1021 aagctagtag tttcttgtga acactttacc acttcactgg tagaggtcga aacattcacc
     1081 tccgcactgt tagaagaatt ttccaaggaa tcaggagcct tagcacaacc aacaagtctt
     1141 tatatattgt gcagccgata ttttcttcat tcagtacacc cttgaaatat gcagtgttag
     1201 ataaagcagt tcgtcctgat ttgctgaggc acccatctct tcttgaacgt actccttgat
     1261 tttcaaggcc gcccgatact ctttcggaaa acgctgcttc actgaagcca gcaaaaaatc
     1321 atccttctcc ggcaactctt ccttcttaat cattcgggca ataaaaaact gtaaatgcgt
     1381 cacaaatctt aagtaaagca tcgaatcttt atcaaccttt ttttcgggaa acagatatcc
     1441 tagcatagcc aagatatcct ttagtgctct taccgagagc atggtttctt ccatatttgc
     1501 ttgttcactt tgggcattta caatgtgaaa cgcaatgttt ccagcctcct cttctggcaa
     1561 ctgaacattc atttttttgt tgatcaattg gatagcatag cagccgatct caaattcttt
     1621 tgggtaatac ttttgaattt caatcagcag gcgattttga aaaacaatgc ctttttgact
     1681 gcgttcaatg gcatgcttca agtgatcaac caaggtaaaa aatagacttt tattcagctt
     1741 aaagtcaaac ttggcgttgg cataatcgat aattcgcttg acgcaaataa ttagatcatc
     1801 cggagcagcc tcaaacagtt taatgtaatc cttttttaga gcatcagaaa gtgaatctaa
     1861 tttaaatact ttttggattt tgtcagccgg aaccaaatcg cctttcttta gttgaaatcc
     1921 aatccctttc cccatcaaaa ttacttcttt gccttgctta tctaagcaaa gaattaaact
     1981 gttgtttaac gttttaatta ctctcattag attcaccgtt ctctctaagc taagccattt
     2041 cttgcgatta ctttttgata ccaaaagaag ctttcttttt ttattcgttt taattcttta
     2101 agattctcat cggttcggtc aacatatata aaaccataac gcttattgaa gccttgatgg
     2161 gtactaacaa catcaatcgc tgaccaaggt aaataaccaa aaacatctac accatctgtt
     2221 aaagctgctt gaatagccag aatatgtttg gctagataat caattcgatc ctggtcatta
     2281 attcgtctat cttcctcaac tatgtcgggt gccccatagc cattttcagt aattaaaata
     2341 ggtaaatcat agcgatcgta caatttcctc aatgttaatc gtagtccagt agggtcaact
     2401 acccagccat atggcgtttt atctacataa ggattttcag ctgcccggta gacaccttct
     2461 tctcccaaca tgatctgttg atcccccgct ctagcggaaa catctgatcc gtcatttttg
     2521 ctggcagcga tggtggcagt tgaataataa ttaatcgcaa taaaatcggg tttaccggag
     2581 gataaaattg cctgatcctc tgcctcaatt ttaggatata atccacgatc attcaaatag
     2641 ttttcaaaca aataattgta ttttccccga actgctacat ctaagaaaga ccagcctctc
     2701 aatgtttccc aattatgggc tgcaattgca tcttctggac tggaggtagc ttgatacata
     2761 gccgttaaat tgattgctgg accgattttt cctttaagat tcaactgatg atacaagtga
     2821 attactctag cttgagctaa taaaacatgg tgattaattt gaaagagttc tttttttgaa
     2881 ggcagctctc cacttggtgg caaaccaatc gctccaggat gaaggatcat cgtgttttgc
     2941 tcattaattg tcagccaata gttcaccttg tcaccatact cagtaagcaa tacctgtaca
     3001 tagtccacaa aataatcgat agttgctcga tttaaccaac cgccctgctc ctctagaaaa
     3061 taaggtaaat cgaaatggta catggtgaca atcggttcga ttccctgatt caggcattca
     3121 tcaattactt gatgataaaa agaaattccc ttttgattgg ttttattatt ttcaatatcc
     3181 ataattcgcg tccaagcgat ggaaaagcga aaagctttta agcctaattc tttaaacagc
     3241 tgtatatctt ctttatagtg atggtaaaaa tccgaggcaa cttcaaaatt agctacccct
     3301 tctgtatgct gatacttgtc aataatagac ggttgtttcc catcctcctg ataggcaccc
     3361 tctgcctggt aggcactaat ggaggcaccc cataaaaact tctctggaaa tgctgaaagc
     3421 tgtttgtatt gcacaaaaat cctctcctta actaatttgc atcaatggtt cgtgttcctt
     3481 taagcttccg cttgcttcac taattcctgc gtaattttca ctgttggtca ctaccacaat
     3541 cactgtatca tcgtagccag cgtttctaat ggcagcgaaa tcggcgttga ttaataattg
     3601 tcctgctgac acctgatctc ctgcttttac aaatacttca aagggttccc cttttaaatt
     3661 cacggtgtcg atccccacat ggatcaataa ttcaatacct tctttagaac gtagaccaat
     3721 cgcatgttta gattctaaaa tagtaatgac ttctccctca acaggtgaat aaatgctgtt
     3781 ttcttctgga tgaatggcta cgccctttcc caatagtccc ttagaaaaga cagcatcgtt
     3841 cacttcagaa ataggacaca cggttccttt taccggattt tcaacaatga ctgcttcggc
     3901 tattgccgtt tgctctgatt catcagaagt atcgtcaaat ccaattagat aagcaatgat
     3961 aaaggttgca acaaaggcga ttacacacgt aataattgcg tgaacaatat tcattggatt
     4021 ttctccaata aaggctggta aggctgctaa gccaggggaa acaaaggcat atctgactaa
     4081 accgctcaag ccagcataca aaccagcaat tgcaccacca atcatggaag caactaatgg
     4141 ttttttcagc ttcaaggtta ctccatagag tgaaggctca gtaattccca ttaaagcagt
     4201 gatcccagtg gacacagcta gctgcttcaa ctctttgttt ttagttttcg cggctacagc
     4261 aaaggtagca cctgattgag caatattaga agccagcatt cctggcccat tgatcatttc
     4321 agaacccgta ctgctcaatt gcatagtagc gattggcgtc attgcccaag ctgtacccgt
     4381 aaccaccaaa aatggctgca aaccacccat caaaaatgga attaaccaag ctgctttgcc
     4441 gttaatccat tcagccccca ttgctataag atcgttcagc aacgttccaa acggtccaat
     4501 gacaaccaac gctaaaggcc ccataattaa aaataccagc atcggcttag taaagaattt
     4561 aataaacgaa ggcgaaattc gatccgcaaa gggctctaca taggacatga tccaaacagt
     4621 aaagataatc ggtaaaactg atcccgcata atctgcagct aataccggaa ttcctagaaa
     4681 agaaacggca tcgccagtag aaaaaagctg tgaaatattt ggatgaagca aaatgccagc
     4741 aacagtaatc gccaaaattg ggttgacatc aaactttatg gctgccccat aggctaatag
     4801 tactggcata aaataaaagg ctgcatcagc aatagtattc aaaatgatgt aagtttgact
     4861 actgtctgat agtacaccag tcaaagtcaa gacggccaaa atggctttta ccatcccggc
     4921 acctgttata gctggaatca tcggtgtaaa ggtggtagaa atgacactaa tcaatcttga
     4981 aataatactt tcttgattgt ctgaagaggg gcccttttta attgaagttc ccacttcctt
     5041 ttgaatttcc ttgaaggctg tttggacttc attgccaatc accacttggt attgtccacc
     5101 gctatccacc acactaatta caccaagtgt tttttctaag gctttcgtat cggctttcct
     5161 tttatctttg agttcaaaac gcagtctggt ggcacaatgg gttaagctga ccacattttc
     5221 ttttccccca acctgttgca atacatttct tcctacttct ctgtaatcca ttattctctc
     5281 tccttaaagc agtaaaaaag accaagtcaa accacgcccc aatcaacatt gaagtgttag
     5341 tttgtcttgg tcttgcctgc ataatcagta acatgccaat aacgttattt tgctgtaatc
     5401 caataatagc acattatgat agcgcaatca acagggaatt taatttttta tcttttcgtt
     5461 tgaccgtata gggtaatata acagttagat cacatcaact agggtatatc tgcgtatact
     5521 tactgctaaa ataagtatat ctaatattaa ctataccagt aaaaccattc ctacataacc
     5581 agcgggaaat tcccaaaatc gtgaaagcat caaaaatgca tataacggat cacacaactt
     5641 caacaattct gctcttggga aaaattgatg aatttggtga gtaaaggatg gaataaacag
     5701 cattccaaca atataggcaa caatagtgat acttgttttt ttggtaaaaa tcagtaagca
     5761 atagccaatt tcaatcattc cgagatataa aggtatcgat agaatgattt gggctagtat
     5821 tcttaaaaat taactagcaa atgtttaaac tgatttattt ctaatctaca tgtagtaagt
     5881 atttcaattc caccaattat caataaaaat accaaacata tccataataa ttttttcttt
     5941 ttcatttctt ttatattgtt ataacagtga ataacataaa aattcccgac aatcattgta
     6001 atattttttt gtcacctgta ttagtattta atttatagga aactataaaa actccctagt
     6061 gaatttacac ctttgggagt tcctgtttgg acggtatgca taatacattt aaatcaattt
     6121 aacattaaca cctcagcata tggtatctcc acatatatac ggtctttctt tggatagtac
     6181 tcaatattta tgttgatagc acttccattg tctaatatag ctttagcccg gtatgtgtta
     6241 tctccatttt catgagtaat cgtcacatca tcacatgatc gatttaagtt gtactgttct
     6301 tgtaaaatct gtgttaccaa tggtttcgat gacttctcta atccagatgt acctgtcatt
     6361 tttgaaaaaa tgatacctat aatagccaag acaacgataa ctataatgat aaacttcttg
     6421 ttcatattta ctttattcaa ctttttatct cctatctcca aaataatttg ctcttatccc
     6481 tcttatcagt acattgacat ccctaaaagt acaccaaaga ttgctccagc tacccctgct
     6541 atcatcaaaa tcgtacccat ttgttcatct ttatctcgat ataagtagcc cataataaca
     6601 gcaacagcac caaatacaac aggaataaat gctaacgcta ctaccataga aatccaacca
     6661 ataatcaaat acagcttccc tgtctcttgt ccatgtacga tttgttcctt catttcatta
     6721 attgtctgct cagtactttt ctttactgcg tctgctccag ttgtctcatc tgtttcttgt
     6781 agtgctccgc aaaactggca atacttactt tcatctgtta tttctttgcc acattttcta
     6841 caatacatgt cttctcctcc taaaaacatt caattgttta ttagttaact gtttacttta
     6901 ttaaatacat cagaaaacag ctcattcatt ggtacactta atatctcaga aagcatcttc
     6961 atttgatagg gtttaggaat cgttctccct gtttgccacg aacttacaca ttgctgtgta
     7021 acattcattt ttttgctaac tccgtttgag aaagtccttt ttcttttctg tatcggctga
     7081 gattacttac ttttttcatg attctcccct cctgttttat tatatacaac aatatgatgt
     7141 atttcaactc ataaaatata aaaaaacttc aaataccatt acaaatacaa caacttgttg
     7201 tactatactg agatgggggt gtattaatga aacagaaaca atatgcaaag gtcattagag
     7261 aaaagcgaaa agctctcggg tggacacaaa aagaattagc tgaaaaaatc ttctctacac
     7321 aacaggcagt agcaagatgg gaaaattctg taacagagcc taacctcgat agcttaaccg
     7381 ctctttctag agccctagga acccctgtaa gccattttct agacaatgtt gtcgtagatt
     7441 atgaggaaga gtttttggct ctctatcgtt ctcttagcac tgaagatgca gttcgaacaa
     7501 ttgactatat gaagctatta aaaaggcaag aaaatgaacg caatcagcta ttgaaagatt
     7561 gaaaaataaa taacccaccg aactttaacg gtgggtgtat tgagatgaaa taagattaag
     7621 agctatggat aacctgtcta gtttaataca attgggtctt ttctcttcct tactctccgt
     7681 ccatcatctc ttgttacact tgtaaattga taaagaggaa ctaattcaac tcctgataat
     7741 atcaattctt ttattacttc atctatccct gctccttttg ctaggtagac taaaaaacta
     7801 ctacttgctt tcacattgta tagtctctta atatccttag aagctcgttc aagagtgaat
     7861 ccttgtttaa caaagtagcc tctgttttct tttaaagcat tttccacgct gttattccca
     7921 acattacgta gacgttcaca aacagtgtta gtaagttctt tctctgtcat tagatatgtt
     7981 ccttgccacg ataagccctg taaaacttca tgtgcttcat ctaaaatcaa ttgtttttcc
     8041 ttgctaagtt ctgatcggga attttgagga aatactcttt tagcctcttt ttcgttaaaa
     8101 catatcttaa cccattcata agaaaaatat tgatatgtaa aatgaaattt ttccagaagt
     8161 ggaaggatat cttcattcaa tttttgaatc acagaagttg cattaaaaac gtctaatcga
     8221 tagacattgc ttctcttatg attaaagttt cctaacgctt tctcttcctt taacctattt
     8281 aggtattcga gcatcttcaa aggaacatct tcatcatcta atttttttat caatcctata
     8341 aaagtcataa gtgatagtaa cttattacat ttatctatgt cataagtttt accatagtaa
     8401 aaactcattt ttttagctaa ttgttccccc gacaaaatac aagtcacact ttccttacta
     8461 tcatcaaaaa aattaacatc agaaagcaag acatcataga cacgtcgcat ttcctctaga
     8521 taattcctta ttgtcctgaa aagtttgtct ttcattgatt caagagtgtc aaaaagtact
     8581 tttgattcct ctttcaattt tcgaaaatgt gtaggataca agtctaggtt ctctaatagc
     8641 caattaaatg tttctacccg actgtctttc tttaaaatta gcatcacaac tccaataaaa
     8701 ttttcactga tatcacaatt actggaatga caataaaaaa tggaatgccc agttttactg
     8761 gtaaaaatac tagcagaggg attatgatcg ttgtgaaaca gacatcttaa gtttttactt
     8821 gacttaagta atttattcat atcaatggtt aacaatcttt cataaatctc attaaaagac
     8881 atgtcggagg aatcaaacag gcagtcttta aaccactgtt tcatttcttc tttgtcgtca
     8941 ttttttatca acttaacaaa atcggtttca ttgactagtt catactctct ccctgaatca
     9001 ctttgacaat ttttagaaca tgtcatggta aaatcaatcg gaagctcagt aatatctaac
     9061 atgttgtctt cattaattat tatcactgca tctgacttat atcctccaaa aaacattcta
     9121 ttcgaagcat ttacattgtc atcacacccg gggatgttct ttttcaagta ttcgtaaaca
     9181 gcaaccattt taccatagtc agtaattgct tcttttaata gaaagacaat cttgtatttt
     9241 tctagatttt cagagtaccg aatacttttt tgtatcgcaa acgcagaatt atgaactaaa
     9301 ttgatagata aaaccttttc tatgcttaag tatctactat catctttact caaatctact
     9361 accttcccct tctcatcttt aacagtgtta tcgacatcca gaataattac tctggtttcc
     9421 acaaaactct ccttgtcatt gcctttattc tttgtcttgc ttggaataaa tgattgtgat
     9481 gaatttagta tctctacaaa ctcatctctt gtaacttctc tatagttatc taaacaccta
     9541 tctcttacat cagttttttc tttttttgta actggcttct ctaataattt ttctttatct
     9601 acataaattg gaatattaat cattgatgtt tccatttgtg tttcctcctt ataaaattct
     9661 gttaaagact aaaacataca gataataaaa acaaactctt tattactata tgttttagtc
     9721 ttatttgttt actcaacctt tataccgttc catgaaacta tcaatatcag attttttaaa
     9781 tctaatgacc gtatcaattt ttataacagg taacccgtat tgagaaacat attttctaat
     9841 cgttcctact gatacaccta gatattcact tgcctgctga tagtccatat actctagagt
     9901 gactccagaa ataatgtctt ctagcatagg ctttagcact gtaattatct ctttcacttg
     9961 ttgttcaact tgtatagaaa caatgctatc aatgatttgt agagacatat ttccccctcc
    10021 tttcgtgatt gcttgaacaa attttctaag aattatcttc gtattttttg ctcaaaataa
    10081 aagtattttg ttattaaccg attaatcaaa caaaaaatga ttaccagttc atcgacatac
    10141 acataatacc tcgataaaaa agaggtgtca atatctttgt aaaatttatt tacaacaccc
    10201 ctttttcgag gtatactaat tttaggaggt gtggtcaata tgataaaacg tccaccaata
    10261 aattatttag aacgaaaaaa gatactcgga acaaaaataa aagctataag aaagagtaaa
    10321 aaattaacac aaccagcatt tggtcttatg attaacaacg gtcaattaat tgacaaaaaa
    10381 actatctacg aatgggagaa gggaacctat ttaccaatac cagagcgatt atcccgaatt
    10441 gctgatttgg gaaatatgag tatagaggag ttagtttgtg gcaatgtaga agaatatatt
    10501 ttgggaatta ttctttatag agatagcatt gtactagatg gtataacatt tccagataaa
    10561 aacctgttcc agcatcttcg tcaacagttc ccaccagtac actctaattt agatacatgg
    10621 ctggatagat attccaaatt agaaccagag atgcaagaat ttattgctaa caagacttgt
    10681 aataaagtta aaaatgaaaa aattagtctt ttcaatatct taaaaataga agaattattc
    10741 atcaatgcta ttgtagaaga atttgacaat aacattcttt tcctcactag cagtatagaa
    10801 gaactactag aaagaatggt agatgaatgg ctacctattc aattgaaaga catgtcttat
    10861 cccgaagaag ctgtgagaga aattactgat aatataaaca agctagaaca aacgatttca
    10921 tcaattggga aaaaatacac taagaaaaaa atgaagggag gtgataccat ctagtggtaa
    10981 gtactccttg taaactaaga ggagatgatt tcatggcaaa aatatcaaag tacaaaaaga
    11041 aaaacggtca agtggcgtgg atgtataaag gacacattgc caccgatcca cgaactggtg
    11101 aaaaaataaa tactacgaga agaggtttta gtagcaaaca agaagctcaa aaagattatg
    11161 acgagtacag acatcaaata ttatacggtg ttaaaaagaa agcacctgat atgacatttg
    11221 aagacctgta taatgaatgg ataactcatc agcgtaccag tgttaaagct tcaacaatcg
    11281 caatctcagt aagatacgca aataatcaaa tacttccagc atttggtaag cttaaactat
    11341 cgaatatctc tgtcccatat tgtcaaaaag tggtagatga atggcacagt aaatatgaaa
    11401 gttacgatta tatgagaaaa cagactgcac aaattttacg ctacggggtt gcaatgcaat
    11461 atattgacaa taatcctatg gaaaaaacac ttcttccacg aaaaaaagag tatgagaaaa
    11521 atcgtaaatt ttactcaaaa gaggagctta ataatttact ggatgctttt aaagattttg
    11581 gtaacatgaa acaatacgcc ttcttcagat tattggcata cacaggtatg agaaagagtg
    11641 aagtactcgc tttacagtgg aaagacatag acacgtttaa taaagaacta catgtcaata
    11701 aaactcttgc tgtagatgaa tttggtaaag ttataattca atctccgaaa acaagagctt
    11761 ctagacgagt tatctcttta gatactgaga ctctttctat cctcaacaac tggaaattac
    11821 agcaaaaaga agagtattta aaacttggat acaatactag ctctaaagag caacatgttt
    11881 ttacaacagt taaaaacact ctatacattc caaacactgt taatgattgg ttaagatata
    11941 ttttgaaaaa atataacttg cctcgtatta cacctcatgg gtttagacat acacatgcta
    12001 gtttattatt agaagcagga gaatctgtca aggtagttca acaacgatta gggcatgaaa
    12061 atagtaaagt gacattagac atctatgcac atattacaaa taatgcacct aagaaaacag
    12121 gtcaagactt tgctgatatg atggctcatc agtaaaagag ctggtcaaaa tctggtcatt
    12181 tctagtatac aggcaaaaca aaaaagctag aacccttata tatcaagggt tctagctcct
    12241 ataacaggtt tacccaacac tgccttccat ctcataactg atcaatcgat tgagttcgac
    12301 tgcatattcc attggaagtt ctttggtgaa tggttcaaca aagcccatga cgatcatttc
    12361 agttgcttca gattcggtca ggcctcggct catcagatag tagagttgtt cttctgagat
    12421 ttttgagact ttggcttcgt gttctaaaga gacttggctg ttgtggatct cattgaatgg
    12481 gatcgtatcg gatttcgacc attcgtccat gatgatcgtg tcacattcga tatgagagat
    12541 cgaacccgca ctgtttttgg caaaggttac ttgtcctcga tagtttactt ctccgccgtc
    12601 ttttgaaatt gatttagaga cgatagagct agatgtattt ggtgcattgt ggatcatttt
    12661 tgcacccgta tcttggattt ggtttgctcc tgcaaaggcg atggagagca tggtgcctcg
    12721 tgcacctttt ccatctaagt aaacacttgg gtatttcatc gttgtttttg cacctaggtt
    12781 tccgtcgatc cattcaacgg ttgcgccttc gtatgctttt gctcgtttgg ttactaagtt
    12841 gtacacattg tctgaccagt tttggatcgt tgtgtaacgg caatacgcat cttttcttgt
    12901 aaagatttct acgatggcgg catgcaggct gttacttgaa taagtaggtg ccgtacaacc
    12961 ttcgacatag tggatgcttg ctccttcgtc aacaatgatc agcgtacgtt cgaattgccc
    13021 cgtgttttcc gcattgatcc ggaagtacgt ttgtaatgga acatcgactt tgacgccttt
    13081 tggcacgtaa ataaaggtcc cacctgacca tacggctgaa ttcagcgctg ctaatttgtt
    13141 gtcggttggc ggtacaagtt ttgaaaagta ctctttgaat aattcagggt attctttcaa
    13201 agcagagtca gtgtcagtaa agacgattcc taacttttcg aattcatctt tcatattatg
    13261 gtacacgact tctgattcat attgtgcgga agcaccggct agataagctc gttcagcttc
    13321 tggtatacca atcttttcaa atgtatcttt gattttttct ggtacgtctt cccagtcacg
    13381 agcgggtttg tcacttggtt tttggtaata tttgatggca tcgaaatcga tgtctgaaag
    13441 gtcggggccc catgtttgca ttggcatttt gttaaatgtt tctagagatt tcagacggaa
    13501 ttcaagcatc cattctggtt cgcctttgat tcttgacatc tcacggatca cttcttctgt
    13561 caagccttct cctgtactga aaaccggttc gacatcatcg tgaaacccga atttatattc
    13621 ttctaattct ggtacgccca tgttctcact cctcttcctt gtggtaatga tggaaagctg
    13681 cggtaccatc gttttccatt gcttttccta gtgctttcca ggcaagtgtc gcacatttga
    13741 tccgagcggg aaatttagct acaccaccaa gcatagcagc atcgcctaat tggtcgggat
    13801 ctttgacttc ttttccttgg acaagctgta gaaagtctac agttaaatgt tctgcttctt
    13861 ctattgattt tccgatgacg gcgtctgtca tcatcgaggc acttgccgta ctgatggagc
    13921 agccactgcc gtcaaaggcg atatttttga tgattccgtc ttttacatcg acttgcaatt
    13981 cgatcacatc tccacatgtg gggttgttca attcgatctt gcttgtcgag tcagtcaagc
    14041 ttccacgatg atgcggatgg gaagaatgat ccaagatcac ttgacggtat aaattgtcta
    14101 atttagatag tcccatgttg gaaaaactcc tttgttgcca tgattgcttc aactaaacgg
    14161 tcggcgtctt gcgttgtgtt gtagaaataa aagctcgcgc gagcagtcgc tgatacttca
    14221 aggtacttca atagcggttg cgcacaatga tgacctgctc tgacggctac cccttccatg
    14281 tctaaagctg tcgcgacatc atggggatgt aacccatcca aattgaatgc aacgactcct
    14341 gtccgaaaat tcgggtcttg tggaccataa acagtcaatc catcaattgc ttgtaatttt
    14401 ggcaacacat aagcggctag ttcttcttca tatcgatgga tattgtccat accgagtttt
    14461 tgcaaataat cgattgcatg gcctaatgcg atagcgccgg cgatatttgg tgtccctgct
    14521 tcgaatttcc aaggtagttc tttccatgta ctgtcgtata attcgacaaa atcgatcatt
    14581 tcgccaccaa attcaacagg ttccatttct tctaaccatt ttcgtttacc atataaaaca
    14641 ccaatacctg ttggtccgca cattttgtgt ccgctgaaag caaagaaatc acagtctagt
    14701 gcttggacat caatggccat gtgcggggca gattgagcac catctactac gatgaccccg
    14761 ccgttttcat ggacaagttc agctaattct tgaacaggat tgaagacacc taagacattg
    14821 gatacatgag caatggagac gattttggtt ttgtccgtaa tctttttcgc tgcatcctcc
    14881 atatccagga agccttcttc tgttagttcg atatatttca agacagcacc tgttcgtttt
    14941 gccaactgct gccacgggat aacattagaa tgatgttcca tgtaagagag cactatctcg
    15001 tctcctgctt tgatatagcg gtcgccgaag gttctggcta cccaattcaa gcttgtcgtc
    15061 gtaccacgag taaacagcac ttctgctgtt tcttttgcat ggatgaacgc ccgtactttt
    15121 tctcttgctt gttcataatc atgggtcgcg cgttctgcta acgtatggac accgcgatga
    15181 acattggcgt tatcgtgttc gtaatagtac gctaatgcct ggagtacttg ttttggcttt
    15241 tgggtcgtcg ctgcattatc cagataaact aaaggttcat cattgacgtc ttgaaataag
    15301 ataggaaaat cattgcgtag ctttttagca tcgatcatcc attcaacttc ccttcgatta
    15361 cttcgactaa ttctttccga acttgttcta cagggattgc tgttaagaca gaaccgagga
    15421 atcctcgaat cactaagcgc tctgcttctt ctttatgcaa tcctctactc atcagatagt
    15481 acatttcttc tggatcaact cgtcctacac tggcagcatg tccagcagtt acttcgtttt
    15541 catcgatcaa aagaatagga ttcgcatcac cacgtgcttt atcagaaagc atcaagacac
    15601 gactttcttg ttgggcatct gcaccttttg cccctttcaa gatgtggccg ataccattaa
    15661 aggtcaatgt tcctttttct cggatcactc cgtgttgcaa aatatgcccg atcgtatgag
    15721 gggctttatt ggttactcgt gtatcgattc cttggatttg tctgcccgag ctgattgcca
    15781 cgattttgac ttctgcgtgt gcaccttctc ctgctaaatc tgagtcaaag tcagcgatca
    15841 catgaccgtc attcatgaca ccaattgccc agtcgacaga agcatctcgt aaaatgtgcc
    15901 cacggcgatt catataagaa gtaatatttt ctcctaattg atctacggct gaatatttga
    15961 tttttgaacc agctttagcg atgacttcca cgatgatatt acctgatgat tttgctactt
    16021 gttctttggt tgtctggaaa cgttccagat aagaaaattc actatgttca tctgccacga
    16081 tcaacacatg cttgaagaag tgctcatcgg atgcgccatc ttgaatgaat aaggactcga
    16141 gtggttcatc gatcacgaca tttttaggca catacaggaa aataccgctg ttcataaaag
    16201 ctacatggag tgcagtcaat tggtcttcgt tcatgtttac tgcttttttc atataatatt
    16261 cttggactag ttctggatat tcgatcattg cagtgaacaa gtcggtaaaa atgactcctt
    16321 tttctgctaa ttccacaggc agttgttcaa aaatcgtcca tgaaccttgt tggacaagca
    16381 caggattgtc tttcattgca tcaaatgccg gaatcgtgcc tgtttcactg atggtttgtg
    16441 tttctttcac atcaaataac gaccagcgat ggaatttcac ccgatcgata tgcggcaatg
    16501 gcagttcatc tgctttcgct agtgcgtctt gacggaaggt tctcatccaa tcaggttcgc
    16561 ctttacttaa agaaaaatca tttaccgcgt caagataatc gagccagttt ttttctttca
    16621 ttcttgctcc cccttacgct tcttcttctt tatagtcgat tcctaattct ttactgatac
    16681 cagcgtagcc ttctgcttcc agacgtttag ctaggtcagc attccctgtc atgactactc
    16741 ggccttccat catgatgtga acgacatcag gtgtgatata gttcaataat cgttgatagt
    16801 gggtgatgat caatgcaccg aaattgtctc cgcgcatttc atttactcct ttagcaacga
    16861 ctttcaaagc atcgatatcc agacctgaat cgatttcgtc taaaattgca aatgtaggtt
    16921 ctaacatcaa caattgcagg atctcattcc gtttcttttc tccgccagaa aaaccttcgt
    16981 tcagataacg ttcagccatt tcttctggca tatttagtaa agccattttt tcatctaact
    17041 ttttcaaaaa tgccataaca gaaattttgt cgttttcatc acgtttcgca ttgatcgctg
    17101 cacgcatgaa ttccgcattc gtgatacctg gtatctcact tggatattgc atagctaaaa
    17161 ataagccaag tcgcgcacgt tcatctactt ccaagtctaa aacatttttc ccgtcaaaca
    17221 aaatttcgcc ttctgttact tcatagtttg gattgcccat gatagcggca gataaggtag
    17281 attttcctgt gccgttaggt cccatgatgg catggatttc tccggttttc attgttaggt
    17341 ttacgccttt aaggatttct ttttcctcga tcgacacatg tagatttttt atttctaaga
    17401 cagacatgca ttataccccc aaattctctt tcgttctcac tcattttaga ctaattgaga
    17461 atgaagcgca atgaccttcc ttactaaaat caaatatctt ttatttatta ttaaacaatt
    17521 ttgatttcta aattagaata ggtataaaaa agatgagaaa taagccatta cagacttatt
    17581 tctcatcttt tttgttccat accttatttt gcatcagcct ttactggttt aacagagccg
    17641 ccccatttgt ctgtgatcca ttcttggact tctttgcggt gaagcacttc aatcagtttt
    17701 ttgattttgt cactgtcttc atcaccttta cgagtcgcaa taatattcac gtaaggagag
    17761 ttgtcctttt caagcaatac ggcatcttct aatggattca accctgcgcc gtaagcgaag
    17821 tttgcgttga ttgcaactag gtcaccttca tcattttggt acgtagaagc taaaagtgat
    17881 gggtcgatcg tatggttgaa cttcaagttc ttagggtttt cttcaatatc atcgaatgtt
    17941 gctgtttcca gatctactcc atctttgact ttgactaagc cagcatcttg tagaattgtg
    18001 atgatgcgtc cccagtctga ttcagaattt gaagtaatga ttgttgcacc atcttttaat
    18061 tcggaaacat ctttgacttt tttagagtac aagcccattg gttcgatgtg gacagcaccg
    18121 gcattgacaa agtcatatcc tttttctttg atttctttgt tcaaataagg aatatgctgg
    18181 aagtaattgg catcaatgtc gccttcttcc aaagattggt tcggtaatac atagtcatcg
    18241 aatttgacga tttcaagatc gattccttca tctttcaata atggtttcac atgttccaaa
    18301 atctctgcgt gcggtgtcgg tgaagcgccg actttcaatg tcgtgtcgtc tgctttattt
    18361 gctgaatctt tgctgtcgct gttgttaccg catgctgcta atcctacagt cagcaaaagc
    18421 gctgctgcaa atccaaaaat tttctttttc atatcctaca tccccctata tcctattatc
    18481 ttttgtctgt tttcttagtt aagaaatcac cgattccttg aacgataaat acgattagta
    18541 aaataattaa agtcgcaacg aatgtcactg ttagattacc acgctggtag ccttcctgcc
    18601 aagcaagacc tccaagtcca cctgcgccga tcgcgccggc catcgcagta aatccgatca
    18661 tcgagatcgt tgtaactgtt aatccagaaa tcaatgcggg aatactttca ggtatcaaga
    18721 ccttccagat gatttcccag taacttgctc ccattgcatc tgctgcttcc agtacaccag
    18781 ggctgacttc acgaaaagca atctctacta gacgggcata aaatggtgct gcggataaaa
    18841 caagagctgg aatggctgct tgcgcaccta gcatagtgcc tacgattgct ttagtaaatg
    18901 gaatgatcaa aaccatcagg atcataaatg gcgttgaccg gaaaatatta ctgatgatcg
    18961 atacgattcc ataaatgatt cgagcatacg gtttgttttt gcgtccaata gagtaaagga
    19021 tcaatcccaa aactaatccg atgatcgtca ctaagaccat tgagattaat gtcatatata
    19081 gtgtatcaag gatagcctga ttcatcgttt ccgggttgat ttgtttaaaa tctagatatg
    19141 tttctgaaaa gcttttatcc acgatggatc acctcaattc ctactccttg ttctttgatg
    19201 aacacttctg cttgatctaa ttctttggtt tcaccagtca tcaagacagt caatgaacca
    19261 aaggaacctt ctttcacttg tttgatcttt ccatacacaa cgttgacatc gatgttatag
    19321 cgtcgaatcg cttgggaaat gactggctcg ttggcatttc tttcgctaaa ggtcaaagtt
    19381 gccaaacggc cgcttggatt ttctttgatg agttcagcta atagttctgt cgaatcagct
    19441 tctggttcga tgtcttgttg tacaaagcgt ttggttactt cttttttcgg ttgtctgaag
    19501 acagtcaata cgtctccttc ttctacgact ttccccaact ccatcacagc gactttgttg
    19561 cagattttgc ggatcacatt catttcatgt gtgatcaaga cgatggtcaa attcaatttc
    19621 ttattgatcg ctaacaataa gtctaatact tcttctgttg tttgcgggtc caatgcgcta
    19681 gtagcctcat cacaaagcag gatctcagga tcatttgcca atgctcgtgc gataccgacg
    19741 cgttgtttct gtccgccgga aagttgtgaa ggatatgctt gtccgcgtcc ttctaacccg
    19801 actaaacgca acagttcttc tgcccgttct ttacgtttgc tctttggtac gccagctaat
    19861 tccagcggca gctggatatt ttcaagtaca gttcttgacc ataacaggtt gaaatgctgg
    19921 aagatcatac cgattttctt tcggaatgta cgtaattctt tgttttttaa ttttgtaata
    19981 tcttgatcgt ttacgatcac ttcgccgctc gtgggaagct caagtccatt caggagacgg
    20041 actaatgtac tttttcctgc gccagaatag ccgacgattc cataaatatc ccctttttca
    20101 acgtttagtg aaacgtcatt gacggcttgg atgtttccgt ttttcccatt gaatgtcttt
    20161 ttgacattcg ttagttggat taatgacatg ccattcacat ctttctctta taatttttca
    20221 aacaaaaaag ccttcgccct cttgccttaa gcaaaaggac gaaagcttga acttccgtgt
    20281 taccaccttg atttaccgtt acttcgcaat aacagcctct tccagtactt ggacttagct
    20341 tctttccgta tactgtcgcg ctgtaacggg cactcccgta gtaagtttgc ttacgctcgc
    20401 ttactctgct ctaagaccat cttccatctc attttcgtta cccattttca gcaaacaggg
    20461 ctctcttcaa acgtccgtga catgtactct tcttttcaaa gctttctcgt ttcatatagg
    20521 attgcttatg attatagcaa ctggaagaat cagtgtcaac ttttttcaag tgattttctg
    20581 attttataat tcgtcaaatt cttttggatc aacatctttg aaacttaaga tccacgcatt
    20641 catttcatct gaatcattca agatattgat atcttcaccg attttatcat taacagaaga
    20701 aactgtaccc gttagcgggc tggcaaattc attgaccgct ttttccgctt caacttcgat
    20761 cagaggttca tcttttttta gcgattgtcc tgcttttggc agattggcaa acgtgatgtc
    20821 tccaagttct tcttgcgctt catttgtcaa accaacacag tattcttttc cattaaataa
    20881 gatccaaagg ttgtcctttt tcttcaaatg cttgcctgcc attttatatc agttctcctt
    20941 cataaatttt ttcattgaat ccaattgcaa caagctggtc ctctcgtaag atcagtggtc
    21001 gcttgatcag cataccatct gtcgataaga cttggctcgc ttttgaagcc gtaaactcgc
    21061 ctacttgatc tttcagtcca agttcccgat atttcatccc gcttgtgttg aacaggcgac
    21121 ggattggtac ttgactcgtt tctagccaag tctcaatcgt tgaggccttc ggtacttctt
    21181 tgatcatatc aacggtttga taactaacgc catgctggtc taaccacgct ttggcttttt
    21241 tgcatgttga acatttcggg taccagtaaa aggtgtacaa ttttcttacc tccttgaaga
    21301 tcttgcaggt gcttcatttt ggtatctcat cgataatatc aacccgatac cgatcatgtt
    21361 ccctaaaatc gaggatcctc cctgactaat gaaaggcaat gggatccctg ttaaaggaag
    21421 taatccgata tttgctccaa tattctcaaa gacatggaac agcagcatca tgatcaaacc
    21481 gcttgcgata taggcgtaaa attcattatt cgtatcgaaa cacacccgaa tcatacgata
    21541 gattaaaata aaatacaaga aaatgacgaa tgcaccaccg ataaagccga agttttcacc
    21601 gataacggta aaaatcatat cggactcacg aacaggcaca tagatattgc ttacgttgaa
    21661 tcctttacca aacaagccac cggtaccaat tgccaaaagt ccttgggccg gctgataact
    21721 cattcctgac gtatcatgga aagggtccag ccatgaatca atacgtgcaa actgataaga
    21781 tttgaatcca actttataaa gcaagtctct tccgccttca gtcgtaacca agaagatcgt
    21841 tcctgctcca acgactactg ccaagattac tacaggtgcg atgatgcgcc aagagattcc
    21901 agacatcagg aaaatcccgc caaagatcgc aagaaagaca agcatcgttc caaagtcatc
    21961 ttgggccatg atcaatgcta aaaccggtat tgtcacgatc aagagcttcc caatcagcca
    22021 aaagtccgat ttcatcgtcc gttcttttac ttgcgtatta tgtttagtta cgatcagtgc
    22081 catcatcaag atgtacgcaa tcttcatcaa ctctgctggc tggaaagtaa acgcaccgaa
    22141 tcgaaaccag tttttagacc ctgttgaagc agctaaattc tgatcataga atttgagcaa
    22201 gagtcccatt accactaacc ccaaaccata aaggtaagga gtcagtttcc agatccattt
    22261 ggaattcaaa tgcatgatga caacgattgc tgccgctcca actaaatacc agacaacttg
    22321 catccctacg cctttcaaga ctgctggatt gttcggatca tggctaagtg ctacatataa
    22381 tgagagcaga ccaatcaaac ataacagaaa gactggtaaa atcacgccat aatcaatacg
    22441 attatcgttc gaagctttta attttttttc catgtttcat cccttttctt aaaaaccata
    22501 ctgctgatta ttatagcggt ccagttagat aatggaaagt ctttccatag acatttggga
    22561 aaaattaact ttccgtttgt gcagttgctt gagcaaatgc agtacaaaag cctactgctt
    22621 atctttagtg tatcatagaa ctttttttga tacatgcaat tatctaccag ctgagattct
    22681 cctcgctgtg agaagtttct gtgctttcat tgtatcgaag gatctcttcg gcaatctcta
    22741 gcagctgatc agaaaccaga ttggttcgtt ggatgaaata aaaatatcga tggaaattca
    22801 acggagtcat tggcacattt tctggaacag agcgcttaga caaaatcgag cgaccgattc
    22861 cttccttcag caacgcaaca attacatcgt tacttttcac gatcatcttc ttatcttgga
    22921 tattcatctc ttcaaaataa cgcttcgtgt aatgaaaaac accagagttt gcttctctta
    22981 caagccacaa tttgcttttt gggtccccag cgatgactag ctggtcttcc atcaaagagt
    23041 atctttgtac gccggaagtc tctaatggct tttcgataaa accaaaatcg gattcatgtt
    23101 tcgctacttg ttctaatgat tcatgagaat tcgtgatttc gatctcaaaa tgcactttag
    23161 gaaacctttt gatcagatgt ttcatcaact gaggcaaaag atggacagca aaggtgtggg
    23221 aagcaacgat ccgacatact tcttcttcat tttgttcatt gagcaatttt tgctgagttt
    23281 cttcccattc ttctaacaaa accagtgtcc gttcatataa taagtcggct tgcttagttg
    23341 gaagcatctc ttttcttccg ttacgttgaa aaagatcgat attcaattcc cgctccaact
    23401 gtttgatttg attcgagact gctggttgag ataaaaacag tacttctgct gctctggaaa
    23461 aatttcttgt ttcatatact gctcgaaaag tcgttaataa cttaaacatg gcaccacttc
    23521 cataactttt tatgataatt actataaaaa ctatttgatt taaatataca aaaaaccatc
    23581 tataatagaa atgtacaaca aaacagttgc tgatccaact agtaacttag atgaagacaa
    23641 tcagctgtct gcttgctcgt aatcatacat tcctattcat tttacaatgt attcgttcat
    23701 cttggtacta aaatctatta aataaaaagg agaatattat atatgaagaa ctttttgaaa
    23761 attattccga tcccgatctg cgggttgatc cttgggttag cttcccttgg aaatctgttt
    23821 aaagactatc accatgttgc tttaggcaat ctaactggcg gtatctctat gattcttatg
    23881 atattcattt ttgttaaatt gtttatctta ttcgaacaca cgaaacaaac gttgcatgat
    23941 ccaatcatcg cctccgtttc accaactttt acgatgtcac tcatggttat ttgtacttat
    24001 tttgtttcat atgaaagtat tgcaccaatt gtcaaattca tttggctgtg cgctgttatc
    24061 ttccaagtga tccttgtctt ttatttcaat tatcaccatg ttatcaaagc tgatctttca
    24121 attgaagcaa tttatccaag ctggtttatc atttacgttg gatttggggt catcactgta
    24181 actgccggga acttcttccc acttattgga aaaattttct tttggatttc attgatctgc
    24241 tatgcgttct tattgccgat catcatcaaa cgtgtctttt tcgtaagaaa tatggctcat
    24301 ccgacacgtc cgctgattac gatcgttgca gcacctggtt ctctttgcct aacaggttat
    24361 cttaaaaact ttgctgaacc taatttttat cttgtcgtag cattgttcgc tttatctcaa
    24421 gtattgtatt tcgttgtgct gtctatgctt ccacgtttgt tcaagcttcg tttttatcca
    24481 agctatgcag cctttacatt cccgcttgtt atctctgcaa cagctatatt tactactgtt
    24541 cattacttca acagtttagg tatctatagt agcgtattgg atttcttaaa agttgcggaa
    24601 tgtctgtttg caagtgtagt tgtcttctac gttcttgctc attacgtacg tttcttaatt
    24661 aaagaacata gcaaacatgg aaaatttgtt tctaaaaaaa tcgcttaata atcgattcaa
    24721 taggttgtga aaaagctgtt ctgcatcaag taataagaac ggccaaacaa aaacagctgt
    24781 tcatgttttt gtactggttg ggcttattac cgcagatgca agcttttgaa caccgtttac
    24841 caagaggtcg taaaagaagt ggtcagcttc aagaaataag aaggaattta cgaaaattgc
    24901 ttctcaaatt tttgtgaaat ttcggcttat ttccgtagaa gctacttctg gaacaccgtt
    24961 tattcgaaac aagaggtcgt acaagacttt tgtcacgacc tcttgttctt ttgtcaaaat
    25021 actggtttag tgctactatg ttcgagtatg cttttagtat ttattgacga aaggaaccga
    25081 tcaaatgaaa tcattgtcac atccaataaa atctgtaaag gattcagcgg tccgcgaaat
    25141 cttacccggt ttactgcttt cttttgccat cgctgccttc agcaggcttc ttgctattta
    25201 tctgccacag ttaggtggag cgactattgc tattttattg ggtattttat taggaaatac
    25261 tttttttaaa cagcctgttc ttgcaatcgg cacaaaattt gctgaaagca aactattaga
    25321 attctctgtt tttttactag gtgcaactgt cacagctcaa acgattgctc aaattggtgt
    25381 aaaaggaatt gtttttgtgt tactgcaaat gtcagtcact atcatcggtg cttacttgat
    25441 tggtaaaaaa ctgcaattca gcgatacttc ttctttgatg atggctggag gaaacgctgt
    25501 ttgtggttct tctgctattg cttcaatcgc cccttccatc catgcgaaag aggaagaaaa
    25561 aggacagatc atcacactag tcaatctact gggtactgtg atgatgttga ctctcccttt
    25621 tcttggatta cagttgtttg gtggaaatct cattgaaaaa agtgcacttt tgggtggtac
    25681 actccaatct gttggtcaag tagtcgctgg ggcaagctta cttgacaatt ctgttgtcga
    25741 attcgccatg ctatttaaga ttctacgtat tatgatgctc gttgttgttg tctatctgtt
    25801 tgaaaaattc atgcacaaga aacaaccagc tctgtttgaa acgccaactg atacgcagaa
    25861 aaaacgaaaa ttaccgcttc cttggtatgt attagggttt gtgatctttt gtttggtcaa
    25921 cagcttgttt tctttacctg tagttattga ccaatcggca cattttatca gcagctggtt
    25981 tgagatcact gctttagcgg caattggtct gcgtttagac tttgcaaaat tcatgaaaga
    26041 aggtacacgc ttcttatctt atggattagc tgtcgggctt ctccaaacag tgatggcttt
    26101 actatttatt tggctgatca aagtttagaa tgaacatgaa aaaacagttg tgattctcgc
    26161 atggaacaat gtccgaatca caactgtttt taattttgca gatatccttc taacaacaac
    26221 aattggcgtt tgatttcaac cccatctatt gcgtttccca tatatcctgt cagttttcca
    26281 ttttgcccga tcactcgatg acaaggaata acgattggca atggattggt tcgatttgcc
    26341 tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa cggctacttc tttatacgtt
    26401 cggatttctc cataaggaat ggtcgacaaa gctttccaga cattttgctg aaaaggcgta
    26461 cctctcttta tagataaagg aacatcaaat tcttttcttt ttcccgcaaa atattcttca
    26521 aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg attcgctttc tgaaattggc
    26581 tgaaaagata cagcagtcaa tccggattca tctgcatcta accataaaaa gccgataggt
    26641 gtgtgtattt tcattttgtt tgctcctagt caatagactg gaacttcctc ctttttctct
    26701 atccaaaact acttgccaac taataaaaat tgttcttaaa agtttgataa accgaggaaa
    26761 catggtaaac taaatacgtt agtttacaaa aagaatacct gttcttttac gtaaaatcaa
    26821 attttaaagg tgttatttaa ggtttattaa attttgaatg taaaccatat ataaacatac
    26881 gattgaaagg atagaaacga tgaaagtatc aattgttgtc ccatgtttta atgaagaaaa
    26941 aactgttcct cttttttttg atgaggttga aaaattcaaa ggtgcccatg agttcgaata
    27001 tttgtttatt gacgacggat caaaagacgg tacgttagca gcaatcaaga agctagcctc
    27061 agcttatcct tatgtccgct ttgtctcatt ttccagaaat tttgggaaag aagcggctct
    27121 gtacgctgga ttgcaagctt ctacaggaga tttagtgacc gtgatggatg ttgatctgca
    27181 agatccgccc gaactgcttc ctgagatgat caaccggatc actacttctg atatcgattg
    27241 tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg atacgcagtt tctttgcgaa
    27301 aaaattctac cagttgatca ataaaatcag cgatacagaa atggtcgatg gcgctcgtga
    27361 tttccgcttg atgactcgtc aaatggtgga tgccgtccta gaattaacag aatacaaccg
    27421 attttcaaaa ggattattta gctgggtcgg atttaaaaca gaatatattt cttatgaaaa
    27481 ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg aaattattca actactcgat
    27541 tgatggtatc gtgaacttct cggatgcacc gttaacgatt gcttcattta tcggcgcttt
    27601 gtcttgtgtc ggttctggta ttgcaatttt gttcattatt ttgcgggcat tgttgtttgg
    27661 tgatcctaca tcaggatggc cttccatggt ctcgatcttc ctgttcattg gtggaatcca
    27721 attgttatgt cttggaatca tcgggaaata tattgggaaa atcttcttag aaacgaaaca
    27781 gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag ccaaatgaat tgaagcctca
    27841 ccaataatat acgtcaaatg aagtaaacat ttttttaaat gaaaaaggac tgtgacaaaa
    27901 gtcttgtcac agtccttttt tccgaataaa tggtgttcca gaagtagctt cttcggaaat
    27961 aagccgaaat ttcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
    28021 agctgaccac ttctatcaca acctctttca tatcttatta cttcttcatt gctgctttta
    28081 gtgctgctgc taatgggctt tcttctggtt cttctgcttg tgcatatttt ttcagcaagc
    28141 gtcgttcttc atgtttggtc attttcttct tctgctcttt tttatcaagc aatttttctg
    28201 tcgttccatc gtatttacaa cggaaataag caccgttttt accttcgatg atttccattt
    28261 tccggtgaca ttgcgggcat cgatgattag agacttttgg atcttttctt ctgcggtagt
    28321 tgcaatctga attggtgcag acatagattt tgccgtcacg tgtgtttttc tcgcgcagat
    28381 tggccccaca ttctgggcat ttcttttggg taatcgagaa atcttgatat tcttgtttgc
    28441 ttgatttgat ctcattcacc aagcgttttg tttctttttc gattccattc aagaaggttc
    28501 ctgcttgttt ctttcctgca gcaatagctt caaggtcttt ttcccagctt tctgtcaaat
    28561 ctggtgttac taaagaggga tttaccaata ctaataattg cttaccttta ggagatactt
    28621 gcagtccttg aggggtacgt tccatcagtt cagatttgat tagtttctcg ataatctctg
    28681 cacgcgtagc tggggttccc agactgtatt tttccatttg accaagcaag cttgcttctg
    28741 acaatggttt aggcggtgca gatagttctt ttttgatggc gaaatcggga ttgattctca
    28801 ttcctttttc ccatttgact gtttccgtct cagtttcagt ttcgcctttc catcctgctt
    28861 ggacgacacg attttgccga aaaatgaatc gttctttacc aaattcaacc gtaacttttg
    28921 tttggctgac tttatggggt tgagcaaaca gtcctaaaaa acgagagaca atcatttgat
    28981 agatttttcg ctcttcatta cttaattttt cataacgtgc tctgttttca gttggcaaaa
    29041 gtgcatggtg atcggtcact ttactgtctt ggaatacttt tgtctgttgg acgatggctc
    29101 cgtttttcaa atactgcttg acctcaggag caaagtcgct gactgcttgc aatcgttctt
    29161 tcatcgtact tttcatgtca tttgtcagat atttgctgtc tgtacgcgga taagtaacga
    29221 tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt tttctttgca gaatagccat
    29281 agcgttgatt ggcttctctt tggatctctg ttaaatcata aggcaatggc gcagattccg
    29341 tttttaattt ttcttggact tctgtgacag ttcctttgct tgtactgatc aattgaacaa
    29401 gtttttgtgc ttcttcttgt gtttttaaag caaattgatt tttttgaagc attttggctt
    29461 gttcttttcc agcttgcaac gtgatcgtga aatacgtttg tggacggaac tgctcgattt
    29521 tcttttcttg gtctctcact aatgctagtg tcggtgtctg cacacggcct gctgataaat
    29581 tatccgcgta cttcacagtt aaggctctgg tcacattcaa tcctaccagc cagtccgctt
    29641 ttgcccgggc aagagcagat tcatacaatg catcatattc tttcgcaggt cttagttgct
    29701 tgaatccagt tttgattgct ttatctgttt gagaagagat ccataaccgc ttcactggtt
    29761 tattgaaatg cacatactct aagatccagc gagcaacaag ttccccttct cttccggcat
    29821 ctgtcgcaat gactgcttct gagacatctt ttcgctgagc cagctgcttg attgctttta
    29881 attgatgtcc tgttttagga agtggtttga ttcctagttt tttagggatc attggcaacg
    29941 tgtccatttg ccagctctgc cattccttat tcagatcttc cggcattttc aatcctaata
    30001 aatgaccaag ggcccaagta acgatcacct tgggtccttc ataataattt ttgtgctttt
    30061 gattagcacc aagcaccttg cttaggtctt tcgcaacgct tggtttttcc gctagaatta
    30121 gttgtttcat aaaattcctt tctgctttct actgtgatgg gctgatgatt tttcaacaac
    30181 gcaagtccct tgtattgctg taaatcatcg tcacactctt cacaccagcg ctcatctccg
    30241 tcattccaaa aggcgctgag aaagttactt tttgcattga tatattcata attttgatgg
    30301 atttcgttcc attgtttttc gtacgcttgt cgtgcttctt cgaaagactc gaatgtttct
    30361 tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc aaggctcatt gtccccgaac
    30421 atggtaatta cttgatacat actcgtgctc cttctttcag cttttctaga ctcatcttag
    30481 tcacttttca agaaagttgc aagaattttc tcttataaaa gggtcattta atgaacatct
    30541 taaaattgtt acaaatgaat ctgattgttt aaggcaaagt agcgataaag ttattgatca
    30601 tccaaaaata gctgtcttct ggatcgattg ttggttcttt tgtaaagtat cctaaaaaac
    30661 gtaaggaaag ataaccgtgg atcatactac gaagttccct gcttcgatga actttttctt
    30721 ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat ctgattcgtt tcatggattc
    30781 catctaataa aacagcttca ttggtatgcg gtacactgat cagtaactca tacactgctt
    30841 gatttgaaaa agcaaaggat cgataagttt ctgcatagat ctgcagtgct tcctgaccac
    30901 tttttcccac aagagcccgt cgcagctggt cattaagttc ctgcagaagt ttcgctgtta
    30961 gcgctgtttt gacatcacga atatttttga aatggttata cagcgaggga gccttgatat
    31021 ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac atccatctct tctgctagtt
    31081 ctcgaaagca gtcgatgatt ttctcttgag acagatttct ttttttcatt tccatgtttc
    31141 ctctcataaa ataaatcctt cactctttca gtttaccacg aaaaagaaag agaaaaaaga
    31201 gactttcatt gataaactac atattgtagt ttataataaa gagctgtaga tgaaaatttt
    31261 cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa aattatttag gaaaagagaa
    31321 acttgggaac aaaacttgtt tgtcttatgg tttggaacat ttatggctgg tatcggattt
    31381 agtttagtca tgccttttat gtcactttac atagatacgt taggtaatta tagtacgtca
    31441 caattgaact tttggagcgg attgactttt tcatctactt tcttggtgac tacgcttatc
    31501 tctccttggt ggggaaaatt agccgaccaa aaaggaagaa aattgatgct gttgcgtgct
    31561 tcattaggaa tggcaatcgt catttctttg atgggttgcg tgactagtgt gtatcaatta
    31621 gtcgcattgc gtctgcttca agggattttt tctggttata tcagtaatgc cactgccctt
    31681 gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc ttggaacctt agcaactggt
    31741 tctgttacag gaacattact tggaccgctt cttggcggga tctctgcttc agcgtttggc
    31801 tatcgcccta cctttttcat tacagggatc atcttatttt tcgtcttctt gttgagtctg
    31861 tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa acatggtttc tgccaaacag
    31921 attttcaaag acttgaaata tccacacgtc gtcatcggta tgttcgtcac aacgatgatc
    31981 atccaagcat ccaacaattc cattagtcca atcatcagtc tgtacattcg ccaattgctg
    32041 catggacatg ggaatgttac gttgatcagc ggaatcattg cttcgatacc tgggattgcc
    32101 actttgatag ccgctccaag atttggtcgc ttaggtgaca agattgggag tgaaagaata
    32161 cttgcgattg gtttgggttt tgcgattctg gtttatatcc caatggcatt cgtcacgaat
    32221 gtttggcaat tagctgcctt acgttttttg attggtatct ctgatgcttg tctgctccct
    32281 gctgtccaag cattgatcac aaaatattcg cctcatcaag ctgctggacg gatcttcagt
    32341 tataaccaat ctttccaagc aactggtaac gtagtagggc ctatgatcgg ctccagtgtt
    32401 tccagtgcat ttggttatcg cggcgtcttt ctttcgactt ctcttcttgt tttggtcaac
    32461 ttcttgcttg tacgacacaa tacacaagag atccatcagc aagaaactgc agaagaaaaa
    32521 gcttcaggag tctccatagc ttcagggcac tctccttctc atagacaata agcgtaaatg
    32581 aaaaacactg cttgaacagt tgtcacagac tgtccttgca gtgtttttgt ttaggcctgt
    32641 tttttcaaga actcagataa gaggaataat cccttttcca aggtttcttt tttacaacag
    32701 taacctagtc gggcatgctt cggtaaatca aaggcacttc ctggtactaa tagtactcct
    32761 gtttcttcta ataaattgat acaaaatgtc tggtcatctt cttcgatggc taatttaatg
    32821 aaagaagtag agacgtaatt gggagcgaca agttcaactt tcggttcatt ggctacccat
    32881 tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt ttcgcgccaa tattttttct
    32941 ttattcttca atgcatgtac agcaagatca tctgacagga ctccgccgca aatcatcgtg
    33001 tagtctcgat actttcgaaa aacttctgcc aactcaggtc cagtagctgt ccagccaata
    33061 cgaatacctg gaatggagta ggttttggat agggaattgg ttgctatacc tttttcatag
    33121 acatctacga tcgacaagaa ttcaccttta tccgttaaag gcgcatatac ttcatctatc
    33181 aatacatatg catctactgt acgagcaatt tctgcgattt tttctaaagt tttccgatct
    33241 agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga tgatttttgt ttcaggtttg
    33301 actaaggctt ctagctgttc taaatcaaac tgccaatctt cttcttcctt caaatgaaca
    33361 aagtcaacag cggcacctaa agatttgggg atgtcatata attgctgata agtaggaagc
    33421 atcgaaacaa catggtctcc tgcttccact aacgcgtata gagctaaaag attagcacca
    33481 gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg tttgataaag agaagcgact
    33541 tcttgtttga aaacatctga tccttcgatc cagccatagt ccaatggttc gtttttgcgt
    33601 ttttcgaaaa atttacttac gctagtccca tctaagccaa cgagttcgtc taatgtcaat
    33661 gcttcgatcg agctttgtgc aatatcatat accgctttct tttcccattt atttagccat
    33721 tcttctacac cgaaatttgc gattttcatg tttctttccc ccttatatct tgatccagcc
    33781 tacagcaagc aacccgattg aaagcagtgc ggccacacaa atcagcccaa tcattacttt
    33841 ttcttttccc gtaatttgat gtttggtttc acgacaagcg atccagtaga agcaaaaacc
    33901 aggaagatag gcaatactac ataaaaggac ataagaaaat cctgctaaaa tgatgcccat
    33961 caattcaaaa actacagcaa tcccaccgat cactacttgt tttttgattc cttcttttaa
    34021 agaaaactgg acttgataga tcccgacaag tagataacaa atcaaaattg ccgctgtaca
    34081 taaagaatag gcaaattgat aggcataatc agtaactaag aaagtcaata agaatagatt
    34141 agtcaagatt gcagtaacaa ctaacgaata agttggggca ttttttttat tcgtttttcc
    34201 ccaacctttc ggcaacagac cgtctcgagc catcaacatc gttgtttctg ctgggagcat
    34261 cgtccaagac aaccaagaac caatgatcga aataatcaag ccgatattga tcagcgctgc
    34321 tccccaattt cccacgattc cttttaaaat atttgccata gcaggttgtg aaatagttgc
    34381 taactcttct tgagataaga cgccgtatgg caagatcgaa gcaaggatat agataaacaa
    34441 taaacaaagc agaccaatga tcgatgcttg ctgggcttct gaacgtttct tcgcgcggtt
    34501 ggctaaaaca cttgcgcctt cgatccctac aaagacccac atcataacca tcaaacaacc
    34561 tttaatctgc aaccagatcg ttccttgctg ccctgttcca ttcactagat tatcagatac
    34621 gttaccccaa aaatcagcag tgaatatatt cactttaaat gcgataaata caaatattaa
    34681 aaataggaat aatggcacta atttacagat cgtcacgatt gtattgatga cgctcgctcc
    34741 ttcaactcca ttgtttacta ataaagtcag accccaaata aaaatacttg caaataaaat
    34801 agaaggaaca ttttgtccac ctttgaatat cgggaaaaat tctcccatgg cgctcatcag
    34861 catcgttgca aaagcaacat ttcccagcca cgcagacaac cagtaacccc aaccactgat
    34921 gaagccacct aatttaccaa atgaagcttc cgcgtaaccg aaaataccac catctagatc
    34981 tggacgcttt tctcctaaat gattcagcga taataccaaa gctaaaatac caatcccaac
    35041 gattatccat gaaaggatcg ctggccctgg agctgcagaa ctagccagat cacttgtgat
    35101 cccaaacaca ccgcttccga ttgacgaact gacaaccaga gcaaccagtc cccatttgct
    35161 aatacccgtc gatttctttt ccatttccat caccctcact tataaaattg aacaaatcac
    35221 ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt aacaaaaagc aactttattc
    35281 atattattgg atattatgaa ctttttacac aagtatttca agtataaaat gaataaaaat
    35341 taattttatt gcaaaaaaac agctatgcta tccaaaagaa aaggtgtttc ttttgttagc
    35401 catagctgtt ttgattcatt taatatcgct taaacgtatt gtaaaacttt tgtttcttga
    35461 tatgcgtggt cgatcaaacc accacccaga cattccattc catcataaaa tacaactgct
    35521 tgtccaggag tgattgcacg tacaggttcg tcgaatacga cttctgcacg attatcatcc
    35581 aataagcgaa ctgtcacagg aacgtcttgc tgacgataac ggaatttcgc tgtacacttg
    35641 aattcttttg gcattggttc attcgtcgta aagtggattt cacttgcatc caagcttgtg
    35701 gcatacaatg caggatgatg gaacccttgc cccacatata atgtgtttgt cgctagatct
    35761 tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc caccgatccc tagtccttga
    35821 cgttgaccaa tcgtataata catcaagcca gcatgttgtc ctttgacttc accatcaaga
    35881 gtgaccatat ttcctttttt tgctggcaga tagttgctca aaaattgttt gaagttcttt
    35941 tcaccaataa agcagattcc cgttgaatct tttttcttag cagtcgcaag gcctgcgcgt
    36001 tcagcaattg cccgtacttc tgatttttcc atgccgccta gagggaacat cgtttttgaa
    36061 agctgttctt gtgataattg gctaaggaag taagtttgat ctttattatt gtctactcca
    36121 cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt gcgcataatg tccagtagct
    36181 acataatcgg cgccaagatc cattgcataa tccaagaatg ctttgaattt gatttctttg
    36241 ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt attcggctag gaaatattca
    36301 aatacacgat cccaatattc tttttcaaaa ttcacagagt aataaggaat cccgatttga
    36361 gcagctactt tcgctacatc cttataatct tccgtggccg tgcatacacc gttttcgtcc
    36421 gtgtcatccc aatttttcat gaatattccg atcacgtcgt atccttgttc ctttaacaaa
    36481 agtgctgtta cagatgagtc gacaccgccg ctcatcccta cgacaacgcg tgttttgctg
    36541 ttgtctgtca tgatatcacc atcatttcaa ttagattctg aaacatctac gagttgaagg
    36601 tcgcaacttt tcagtatttt acattatacg tcatatttct gaaaatttca tcccttaatt
    36661 atcaagtcgt aaaaatactg ttctactgga cctattcagt acacaaacat gatagtcaac
    36721 caaaaaatca ctcatctttt gagcattcga tataaaaaat tggcatactc ataaaaaggg
    36781 ccagcctttc ggcaataagg aataatttta taaattgtga aaaactattt ttcaaaattg
    36841 cttcttatcg cttaaagctg cacgtctcat ttacaacctt ttctttttag atgttatgag
    36901 ttgctcagat aagtgatttt gtttactcta agaaaaaagg gaggcaaaag atacatgaat
    36961 tactttatca gtgatatgca ctttttccat gaacgcttat taggaaaaaa cgactttgct
    37021 ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt tgatcactag ctggaatgca
    37081 gtaataaaag aaaccgacca tgtttatcat ctaggcgacc ttgctatgca tccgcaatat
    37141 gaaaaagcaa atgcagaaat tttggaactg gtcactcaac tgcaaggaac aatccacttg
    37201 atcaaaggga accatgacag tcgcgctttt ttccgttatt tagaaaaaaa tgatcctagg
    37261 cttactgacg gaagtcccaa attttatttt tatgatgtag gtgccatcgt taaattcgac
    37321 catcaacaat attacttgac tcattatccg atgttgctcg ggcctaacga cactatccgc
    37381 aatcttcatg gacatatcca tcattacagc gtacctatcg agaacgatgt caatgtaggc
    37441 gtagacgcac cggaaagaga actcttaaag gaaaaactac catttggcac tccgttatct
    37501 gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt acgataggtc gtgaaaaaac
    37561 tgccctatat caagtattaa acaaataaag ataattactc atatttttca tttgagtagg
    37621 cttattgcca caggaacatt aggatcagaa atggagttgt aacaagactt ctgtcacaac
    37681 tccattccat actattcgtc tttttgctca tggtgttctt ttaccagttt tttctgtaat
    37741 tctttatcat aatttcgggc agctgacgtt aaaaataaaa cgattccgca taataaaatc
    37801 ccgattccgg aaaacaagaa cattttttct acccctaaac gatcagctaa tggtcctgca
    37861 aataataatc caattggacc tgccaggttc atcaaagagt tgaagttccc taagacacga
    37921 cctaaaacat tcgattcata actctgctgg atcattgcca tcagcagtgt attgaaatat
    37981 ggcgttgcac aacctgctcc tgcattcaag ataagaaagt acaagaaccc ttgactatcg
    38041 tttggaacca atccgcttgc accgatcgtc aggcccataa tgatgtaggc tataataata
    38101 ggtttcattc ggtctttcca tgttcctata aaactgatca gtgcaccgcc taagagcatt
    38161 ccgactgcgt agactacttc cactgctccc gcctgtccaa cggaaccacc aaagtaatct
    38221 agcgtcatca atggatacag actgattgct ggcatgaaca acagcatcac aaatgcacca
    38281 ttgatcgtta tgtaccataa ccctttatta tccatcaatt gctgcagccc aaattttgca
    38341 tctttaaaaa tagtaagcgg aacttccaat atttcaggag aaacttttgg gatcttcaca
    38401 aaaatcaata agccgacacc aaaaactgcc cccaatacat ctaataaaat aaggtaattg
    38461 acaggaacga ctgaaaacaa agccgcacct agagctggcg caatgatgaa attcgctgat
    38521 tggaccattc ctaactgtcc attcgtcctt gttatgtgag aagatggaac gattgtcggc
    38581 ataatcgact ggatcgttgg catttggaat gtttgtgcga ccgaacgcat aaacaaagac
    38641 acaaaaacta gccaaatcgg gaaggattct gaaatcgttc cgactactgc taaaataagc
    38701 gcgaaaatcg ctacaataat atccgtgaca atcaaaagag cttttttatc ccagcgatcc
    38761 actagcggtc ctacaaatgg gcttagtaaa accatgggaa tcattcctag taaagtagca
    38821 aaactcaaaa ttgtcgccga accggtttct cttgtcaaat accagatgat cgcatattgg
    38881 acgaccatac tagtgattcc tgacaaaaac tgtcccgata aaaagaacaa ataatttctc
    38941 ttccaattcg ttaaaacgac cgactgttca ttttccataa acatccctct tttctttttc
    39001 attttgtata gcgtttgcac aacaatcatt atacgggatt cttttttcaa aaaatacctt
    39061 tttccctaaa taacaatcgt ttcaatttaa atttctttac ttagaaacaa taaatcagca
    39121 aaatattaaa aataacaaca tgtgttaaat ttaaaaataa aaaagacaac taatttgcgt
    39181 cgtccttaca aagttagtca tctaacaata ggccgtttca aaactagttg tctttttata
    39241 tccacagatc attcgacttt ttcgaataac ccacggctaa tcatcccatc catcagaaaa
    39301 taaaatttat cttggctcat tttctgtttt ggatctttga aaatattgac tgctttcaat
    39361 ccatttgctg tagtgatcga cattttcaat gtttgaatat cttttgatac agtgattttt
    39421 aatttgaatc cttctttgct ttgcggcgtg gcatctaatg gtcggatcaa ttgataattg
    39481 cctccgtttg tttctgtaaa tccattatcg cgcaatgtat atctttttgc atcaggatgc
    39541 aaacgatagc taattggtgc gcccagtacc gttgctgttg tttcaaatgc catgattttc
    39601 acctcgataa aattagtttc tctttattat aaaagtttat cctgattttt actaggtttt
    39661 tcagttaagt tccctaaaaa atgaaggcgt tctctcagac atctgttcat ataagaatga
    39721 cttcactagt tattttttga cagcacgaac taattgatca aggaaatact ggatgtcgtc
    39781 ttcggtattt cccaaaccaa agctgatacg gatggattct tttagtatcg gtgtatcttc
    39841 tccatacatt gcttctaata cgtgtgaagg ctcgatattt cctgctgtac aagctgaacc
    39901 agtagaaata gcgaccccat taagatcaag cttcatcagt agcaaatcat ttgcttcgcc
    39961 aattaagcga agattcaaca catgagggag tttattcgtt aaatcaccat ttacttgata
    40021 agggatttcg tttgcttcta atgtatcaag aatcaattgc tggaatcctt tatatttgtt
    40081 gttacgtgct tcacgttctt caggtgacag cagttcaact gcttttgcca taccccagat
    40141 ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc tgctccccgc ctaaaagcaa
    40201 tgcagggata tttactccgt ctcgtttata taagaaaccg acgccttttg gcccattgat
    40261 tttatgagca gagatactta ataaatcgat tcctaattct tctggatgga tcgtttggtt
    40321 tccgtacgct tgtaccgcat ctgtatggaa ataagctgga tgatccgcta aaagttcacc
    40381 gatttctttg attggcatca aatttccgat ttcattgttc ccgtacatca cagagaccaa
    40441 gatcgtatct tctcgtaacg cttttttgac ctcttcgatc gacagattcc ctttttcatc
    40501 tacaggcaga tatgtaacgt caaacccctt tgtctctaaa tatttcatgg tattaagaac
    40561 agcaggatgt tcgatagctg tagtgattag atgtctgcct tctttttgac gcgagaacgc
    40621 tgtttctaag atagctgtat tatccccttc tgttccccca ctgttaaaga tgatctcgtg
    40681 aggttttgct tgcagactgt ctgcaatgat ttgtcttgct gtttccaatt tttcatgcgc
    40741 gtggcgacca aatccatgta tgcttgaagg atttccaaac gtgtcttgca tgattgccgt
    40801 catcgcttca attacttgtg gatgcatggg ggtagttgcc gcatgatcca gataaatagt
    40861 tttcacttca ttcatccctt ccaaattatt gctaggcaca ttctagcata aaatagcgaa
    40921 caaaccaaag aagagctcat ttttgtctag aggacgtttc atgggcatag aaaaaaggag
    40981 ctgtgacaaa agtcttgtcg cagctccttg aagctgctca cttctgtcac aacttctttc
    41041 cctctttttt ttgtttattc gaattctttt tcttccagac ggaataacgg actcatcggt
    41101 gtattttcat ggatgcgttt gaccgcttca cccattaatt ctgaacatgt aacgattgtt
    41161 aagttttctg gatgacgatt ttcttctgtg aaaacagaat cagtgataca aatatctttg
    41221 attggtgcat tgtctaaaat acttttcgca tgatcggaca ataatccatg tgacgcacag
    41281 gcatatactt cttttgcgcc gttttctttt aatacatttg ctgctcgtgc aagcgttgct
    41341 cctgtgttca agatatcatc taccatgata catgtctttc cttgaacatc accgatcaca
    41401 taaccaccct cagttgaagc atcatctgca tgatctacga tggctaatgt gctgttcaaa
    41461 tattctgaaa gactacgtgc acgctgaaca ccgctgtttt ttggcgaaac aactacgatg
    41521 tcatctcccg tcagacctaa ttgacggtaa taatgagcaa acaacggcat cgtaaataaa
    41581 ttatctacag gaatatcaaa gaatccttgt acttgaaccg tgtgcagatc taaagtcagt
    41641 actcgagttg cccctgcttc ttcgatcaag ttagcgatca atttcgcagt gatcggttca
    41701 tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt aaggcaatac gacattgatc
    41761 gttttcgcac ttgctcgctt cattgcatcg atcatgatca gtagttccat atagtaatca
    41821 ttgacaggtg cattcgttga ttgaacgata tacacatgat cccctcgaat actttcttcg
    41881 atattgatgg aaatctcgcc atcactaaat tgcttcacga cgcttttacc taattctgtt
    41941 ccgaacactt tcgcgatttt ttcagctaat ggacggttgc cattcaaact aaaaatcttc
    42001 aacgtgtcat cctgatactt attactcatg tagtcctccc caaaacttct ctattcttcg
    42061 atagtttaac atatttttcc aagattttct gttaatttca gcaaattctt aaggaagtga
    42121 aactgttccg ttactccaac tggcaggaat gactttatga taatcgcccc agttgtcgtg
    42181 tactttgtaa taacgttctc ctgtttcagt ttcaaaataa gcgtacgctg tcacccaatg
    42241 attgccatat gtactgccaa gtactttcaa aataccaatc atcacaggtt tgccttcacg
    42301 tatacgtttt gtagctcgct gccatgaacc tagaagagtt gctcgtgcac gctcatgatt
    42361 gccattcttc tttaaaaaac tagaaatccc tgtactaacc tgaaaaggaa tcgtaggaag
    42421 tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa accaacgaat cagccgtatt
    42481 tttcttgcga atctcatttg gaagcatcca ccccttacga tagtcttgat aataggcaag
    42541 gagaactgct gccgcgtaag taccacaaag atagcctgag ggggtagccc atttcttata
    42601 cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt gcgagttcct ttcctgacct
    42661 tttttcttcg atcaaaacgg gaatatcttc ttttctgttg atccatctag ataactcgat
    42721 tggctcttca ttgatcagct tccatttttt acaagaaaga ccctcttgat aagtatattt
    42781 tgctggagaa tattctaccg gatgtcctga ttgatcgata atcacataac tttgatcttc
    42841 aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac tgcagctgct gagtgctggc
    42901 taatttttta atttttttat ctactttgaa atataaaggt ttatccacta cttgattcag
    42961 ttgggatcgc ctcctttttt tcattataag tgaaggattg aaaaaaacaa atcagtttga
    43021 ttgttcgaat tttcaatttt ttatgttcta tttgttaatt ccttcatttt gtaagataat
    43081 gggcacacga aacaaaaaag gagcgatcga tgaatgaaca aagaacgatt gaaacaagat
    43141 ttctatgaag cagtcaatga agaatggcaa aaaacagcaa aaatccctgc agataaacca
    43201 gctacaggcg gtttccaaga tttagttgac gggatcgacc aacttttgat gggagaaaca
    43261 gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa aaatgaaaca tttccttgca
    43321 tattatcaac tggcaaacga ttatgaccga agaaatgagt tgcatgctca accgcttcaa
    43381 cctataatcg aaaaagttga atcattgcag tctttcgacg aattgaataa gcaatttcca
    43441 gaatggctgt tggatacatt accattgcca tttaatctgg atgtagatgc agatatgaag
    43501 aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt tattccttcc agataagacg
    43561 tattatgcat cagaccatcc caacggtgca caactaatag gcgttttctt tgatatggct
    43621 gttcagttat tagagcttgc cggcaaagaa aaaagtcagg cagaagcaat cacggaacaa
    43681 gcagtgcaat ttgataaatt gattgctcct catgtaaaaa gtgcagaaga aaacgcagat
    43741 tacagcaaaa tgtataatcc gcaatctttt gatacattta ttaaatacac agataaactg
    43801 gacttgaaaa aacttgtcac gggtttgatt gggacaactc cagataaagt gatcgtaact
    43861 gatccagtgt acttcgatca tttgaatgac atcctgacag aagctcattt tccgttattc
    43921 aaaagctgga tgatcattaa aacagtacgt tctcttagtg gttatctatc agaagaattc
    43981 cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa cagacgaagc aatgcctcag
    44041 aaaaaagcag cgtattacct tgcctctgga caattcgatc aagtagttgg cgattactac
    44101 ggaaaaaaat attttggcga agctgctaaa aaagacgtag aacaaatggt gaaaaaaatg
    44161 atcgccgttt ataaaaaacg tctagaagaa aatgactggc ttggggatgc aacaaaagaa
    44221 aaagccgtca taaaattaaa taacttaggt atccaagtag gctaccccga taagatccca
    44281 gcattattcg accagttcaa aacagtacct gcagatcagg gtggtacttt gctttcaaat
    44341 actcttgttt tcagcaaact cacattaaaa gatcgtttca gcaaatggaa caaaccagtg
    44401 gatcgttcag aatgggaaat gagtgctgac acggtcaatg cttattatca tccatttcgg
    44461 aatgtgatcg tctttccggc agcgatcctt caagcaccat tttacagtct agaacaatca
    44521 agctctgcta attatggtgg aatcggagct gttatcgctc atgagatttc ccatgcattt
    44581 gataataacg gcgctttatt tgacgaatat ggcaacttga acaactggtg gacagaagaa
    44641 gatcttacac aatttcaaaa caaagcacaa gcaatgatcg aagaattcga tggtctgcct
    44701 tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg aaaatattgc tgatgcaggc
    44761 ggtctaagct gtgcattgga agcagcaaaa acggaatcag atctttctat cgaggaattc
    44821 tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa aagaatacca acaactttta
    44881 ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa acgtgcaacc aaaaaacctt
    44941 gacgaattct atgaaacatt tggtatcacg gaacaagacg ctatgtatct agcgccagaa
    45001 aaaagagtgc gaatctggta agaggttgtg ccagaagtgg tcagcttcaa gaaataagaa
    45061 ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt cggcttattt ttcgaagaag
    45121 ttacttctgg aataccatgt attagaggtt gtgaaaaagc tgcttagttt caagtagtaa
    45181 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgactta ctaccgagaa
    45241 actggctttt gaacaccgtt tatcgagagg ttgtgaaatc agcgtcctga cctgagtatt
    45301 agagaaaaaa acggaaaaat agttcctcat attttgccgt ttgttgagct aataccgagg
    45361 gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa aagctgtcct gcatcaagta
    45421 ataagaacag ccaatcaaaa gcagcaagga gaacctcatc tataaaaaga tagaaggaag
    45481 tgagacatct attggtctca tttccttcta tttttacttt cctcagtcaa ttgttttaca
    45541 tcataaaagg agaaattcca cttatttttt tcgctgtttc atgacataaa caactacacc
    45601 gattaacaaa attcctccag ctaatgctag caacgggtta ttaaattctc ccgtttttgg
    45661 gagtccttga gtgccatttt tttcactttc ttttgctgtc ctatccggat gagaaggttt
    45721 tccatttggt tttccatttg gtgattcatt tcctggattt tctctttctg gtttgtcatt
    45781 tcccgggggc acatcggcag tttctcgcac agtgatcgct ttttgctggg taacagattc
    45841 tgtatgagca gaccattttt ccccatcaaa tatttccgaa cgataagtga cttctagcgt
    45901 atattctcct tttgaaggtg ctgaaaaaat agcggtatga ttagaaaatt gagcacttga
    45961 ctgtgtttca acgatttgga tcttttctgg gaaataacgc atatcttcaa agacaggcgt
    46021 tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt
    46081 tccttctgca ttctccgcca caccatttgc ttcttgtata ataatcggat tattttgttc
    46141 atttggtttt gtctgatttg gttcttgtac gattgcatac tctggatatt ccgaagacgg
    46201 tgaggtttct ccgtcaaaaa tagcacctac agataatgga agaccatcca ctctttcctt
    46261 ttctgtttga cgattccccg gtttaatctg catcagtcca tgaacatgga tacttccatt
    46321 ttcatagcgc gtaacaggct gctgaccttc tttcgaacat gtatttagag actcgatcca
    46381 atcttttgat atggtatgtc caagagtatt ttctgattgt ttctctcgtt cattccaata
    46441 gtagttcaac gagtggtaga tttgatcttc gttttgattc aatgggcgga tctgctctct
    46501 catctcaaga ttctctgttc ggaaagataa gataccagaa gcatggtagt ctgtgtttcc
    46561 tgctgaagag gtataaagag ccacattata tgaaccgtta ttaaaacttg tactgctatt
    46621 gacgataata tctgttccgc tattggaatc gattcctttc gcaagatttt cgaaagacaa
    46681 actattgatc aattcatgag ggcccgttaa agaagaaccg cccattttga atccattacc
    46741 gttaccttct ccctcaattc ctggtaccca gccgtttcga taagcaactg agtttttgat
    46801 gattactttt ccgatcgaac ctgtttcatt tttagcaaaa aggtcccaac cgtcatctgc
    46861 attatgatac gcgatacaac cgtcaaatac atttccttct cctattgtca gtttggccgc
    46921 aaatccatcg gcatcttcaa atcctggatc ggcattttca aaagatgtac agttcttgac
    46981 taagttatgc gcgggccatg cttcgaaagg atcatttgag ctaccgctga tttggattcc
    47041 tgtatttcca ttccgataag catgaatctc ttcgatcaaa ttatgatttc cagaaatctg
    47101 taatcctttt tgcatagctg cactatttgt aatgtcaaac cctcgtaaac cccagtagtg
    47161 actgaacagt gtcatcccat ttccagttcc tttaaaatca agtacaggac gcttgttttc
    47221 tggatttttc tctgcaatca actgaatcgg gttttctctt gtcccgttaa cgccttttgg
    47281 aatcgtcaat cctctttcga aggaataagt tccaggcgcc atgacgattg tctgcccagc
    47341 atatgcgtat ctcaatgctt gtgtcagaga taatggattt tgtctgcttc cgtttcctgc
    47401 atctgaccct tctggtgtta cataaactgt cgaatattta ggtttacggt agtccactgt
    47461 atgaagaatc tcttttgttt cataactagt catctctacg tattcttctg gcggatagtt
    47521 tttatctggc gtaaaactga aagtaaattc gttcgttcct tccatcagtt ttgtctgata
    47581 atcaaattcc cgattcgcag tgatagccaa gttttttgcg ttcttaagca cctctcctgt
    47641 tgctttattt ttaattgtca ataatccgtc agcatttgct ctaaaggaca tagtatgatc
    47701 ttggtttcct gaatgattac tagaggtcac agtgtaaatc ggatcaatca agcgagtagg
    47761 tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa gcaacttcga ttccttctac
    47821 cttgatcgtc atattccttg ctgcagcaaa tcctgcataa ataaccgatt catctgaagc
    47881 gtataatttt tcccagtcat acatgatgtc agaagccatt tcttctcctg tttcaggatc
    47941 gtaataatat gcctctaaac cagtattcgt ttttttcatc tctacgtcca gtttagtaat
    48001 cgagttcgtg gccggaaaca gattcccatg accgtttccg aatatattat aagaacctgt
    48061 ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt gtttccactg agacactccc
    48121 aggagctggc gcagcttgcg gatcttcaga tgatattcct gtgattgccc gtgtccccaa
    48181 tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc acttcttgtc tatccgagtc
    48241 ccagacatat tcgatccgac tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc
    48301 aaacaaatga ttttttggta ctgcgtctct taccattaaa gcaaatcctt cttgggcatt
    48361 cgtataggtc caagattcta tttcgatcgt cgcccgcatc ctaaagttga tgtctttggg
    48421 gattgcttga taataatagg tcattccatc tgatccgctt gactggaatt ttccgccgtt
    48481 attcgtggaa gagagccgca cgccgtcttc taatggttca atggcatacc tactagcact
    48541 tgtgctttct ccgaaaacaa cccctttcca ctcttcattt gcttcttcag attgcttttt
    48601 tgtcttttca ttttctgatt ctttcatcat aggatcattt ccttcttccg tatccatatc
    48661 ttcactagtt cttggtattt cctccattgt tgacatccct tcaatgttca cgtgtgcatt
    48721 ttcttcgttc acagactgtt gttcgttagc agcaacttca acgacagaaa ttaaaaccgg
    48781 ggtactgagc ataaggagat tcatcattag cgcactgtat tttatacgtt tttttaacaa
    48841 gtgtattcct cccgtaacaa attagaaagc gtttacttaa ag
//
LOCUS       DACCVZ010000012        48442 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.012, whole genome shotgun sequence.
ACCESSION   DACCVZ010000012 DACCVZ010000000
VERSION     DACCVZ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.012"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(47..871)
                     /gene="iolB"
                     /locus_tag="IVW63_000671"
     CDS             complement(47..871)
                     /gene="iolB"
                     /locus_tag="IVW63_000671"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HAP7858970.1"
                     /translation="MEKTLKHQPLNKELAPGVKQIQNIRQSNSALSYIEFQILELEKG
                     ASYKETGSQQEVCIVILTGKIKVKAADTWYEDLGTRESVFEKIPTDSIYLPAEHSFEL
                     VATTDNVRLALCYSPAKKALPISVIRAEDNTVEERGLYQNKRLVHNILPDNVDTASSL
                     LVVEVYTEGGNFSSYPPHKHDQENLPHESFLEETYYHELDPEQGFVFQRVYTEDRSLD
                     ETMTVEHQNVVEVPKGYHPVGVPDGYTSYYLNVMAGPERIWKFHNEKKHEWILQRK"
     gene            complement(910..2826)
                     /gene="iolD"
                     /locus_tag="IVW63_000672"
     CDS             complement(910..2826)
                     /gene="iolD"
                     /locus_tag="IVW63_000672"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HAP7858971.1"
                     /translation="MEKTVCLTTAQALLKFLNQQYISIDGKETPYVEGIFHVYGHGNV
                     LGIGQALELEPGHLKSYSGKNEQGMAHAATAFARQNLRKKIFAVSTSVGPGAANLLTA
                     AGTAFANNIPVLFLPADTFATRQPDPVLQQLEHASSVAFSTNDAFQAVSRYWDRINRP
                     EQLMSALLRAFEVMTNPATMGPATICLPQDVEAEAYAYPEEFFKKRVHYIDRRIPTAR
                     ELAEASQRIKASKRPVIIVGGGCKYSEAGEILEQISRDCQIPLVETHAGKSTVSWDFK
                     NNLGGMGILGTSAANKAVQQADLIIGIGTRYTDFTSASKSIFNFEQAKMMNINVSRQQ
                     AAKLEAFQVVGDAKATLEQLAPMIEGYQTAYGEKIDELKEEWISERNRLKAAHFKRKD
                     FTPEIKDHFSQEILNEYADALATNLTQTEVFIHLNDFVDEDAIVIGSAGSLPGDMQRL
                     WNPVKENTYHLEYGYSCMGYEIAGAMGVRMARPEQEVYALVGDGSFLMLHSELVSSLQ
                     YDKKINIVLFDNSGFGCINNLQMDNGGASQGTEFRNTKDEIMNIDYAKVAEGYGAKTY
                     RVSSIAELQAAVEDAKKQTRSTLIEIKVLPKTMTEGYDGSWWNVGISEVSGKAAMQEA
                     YKAKQAKLATIRKY"
     gene            complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="IVW63_000673"
     CDS             complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="IVW63_000673"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018593001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HAP7858972.1"
                     /translation="MSYIKFDQSKEFDLLLLGRVAIDFNPAYNDQVKEEFKPLKKVHM
                     FEKFVGGSPANIAVGVTKHGMKAGFIGTVSDDQFGEYVIDYFNEQGIDTSQISKAQHG
                     EKLGLTFTEMLSSKESNILMYRNQAADLQLSVEDIDEDYLKRSKALLISGTALAESPS
                     REAVIKAVMLAKRNNVKIIFDIDYRAYNWKNNDDISIYYSMIAKESDIIMGSREEFDL
                     TEKLIQPNMSDNESAAFWHSCGAEIVVIKHGMKGSTAYTADQQQFSIKPFPVEARKGF
                     GGGDGYGSGFLYGLFEGWEIIDCLEFGSAEASMMVKSNNCSDSLPTTQEVKDFITLEK
                     EIYGEMIARI"
     gene            complement(4028..5044)
                     /locus_tag="IVW63_000674"
     CDS             complement(4028..5044)
                     /locus_tag="IVW63_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP7858973.1"
                     /translation="MAGTIKEIAEKAGVSRGTVDRALNDRGRINPEVAERIRAIAKEM
                     NYVPKKKKVIKETTLKLGIVTQLAKSSFMIPIRSGLESIIGDLKKRNIDCFLEEVDGV
                     DEAAQLQALDRLVELGVKGIAIMPVDSDGIREKINQLTDQGILIITFNSDILGTNRQC
                     FVGMDNFKSGKTAAGLLGMLTKGKGKVLAITGYFGNSVNSLRVAGFVEELKESFPELE
                     LTGVQSSFDSSAEVEKILSNTLENYSNLDGVVVFSGGQAGIARALEKIDESKRPFVII
                     YDLTKNNIEMLKNDQVDFLIDQDGFVQGYRSLLMLANQLQNNKTVTKDALFTDIIIKT
                     KYNI"
     gene            complement(5146..5343)
                     /locus_tag="IVW63_000675"
     CDS             complement(5146..5343)
                     /locus_tag="IVW63_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7858974.1"
                     /translation="MKFICLSCGEKESIPMDVVKFLDDADIANDPNNPPQFTCEKCGK
                     EMYPEYYRNALGIEFKISDVQ"
     gene            complement(5315..6634)
                     /locus_tag="IVW63_000676"
     CDS             complement(5315..6634)
                     /locus_tag="IVW63_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011674482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HAP7858975.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKYGRKIRLVVKREVNKFRYCGD
                     IQKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGIVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEEYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITEEFGENPLECSCCGEYYEFVGMSVRKNGRLVIKYAKDNHA
                     KRFMREENRKIDQKEFRQQYEEEKEKTFKAIRWDWERQREIYMSKLW"
     gene            complement(7375..8355)
                     /locus_tag="IVW63_000677"
     CDS             complement(7375..8355)
                     /locus_tag="IVW63_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAP7858976.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENIKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFERASQFAEKMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVKKAKENNLGKLIF"
     gene            complement(8368..9246)
                     /locus_tag="IVW63_000678"
     CDS             complement(8368..9246)
                     /locus_tag="IVW63_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAP7858977.1"
                     /translation="MIRNILLTLIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFIIFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGIKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAALLIFAGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFNEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYILKWIVILVLLYS
                     AYTMLGSQLKKVTAAN"
     gene            complement(9262..10062)
                     /locus_tag="IVW63_000679"
     CDS             complement(9262..10062)
                     /locus_tag="IVW63_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HAP7858978.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKISGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTKNLGMIKEK
                     DEEEMLWKVDGIEYVLDKVEHLVKNAKESLLIQVWHENFTDSLLKALQQAEKRVDKFV
                     LILFSSTHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESPEELKAKYGEGFEGIRKIY"
     gene            11454..11780
                     /locus_tag="IVW63_000680"
     CDS             11454..11780
                     /locus_tag="IVW63_000680"
                     /inference="COORDINATES: protein motif:HMM:NF013698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP7858979.1"
                     /translation="MFKIFRKNCCGLDVHKTWIYACIGITDANGRTVYKQARFSSFTK
                     GLNELAEWLAKYNCKDVCLESSGKFWIPVFNILEKTCFVTLAHPKYTKPQKGNKTDRK
                     DAKMDL"
     gene            11788..12696
                     /locus_tag="IVW63_000681"
     CDS             11788..12696
                     /locus_tag="IVW63_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP7858980.1"
                     /translation="MCDMIKPSFIPGLEIRQLRDLMRYRTKLTNMKTSEKNRALNCLT
                     VSNLKLDDVFSDVFGKSSTSIIQYLLEHPGESFDVRPFIHARCKTPVEEIQAAVEGAI
                     SVPQAIKLRQCLNHINEIEKHREEINLEIQALAEPFSPVLELLRTIPGLDTQPITAIA
                     ILSEIGPDMSVFPTSKHFISWAGCCPRNDRSARRTKSTRISRAGQSLKPLLVQIANAL
                     LRSKEHPEFKNRYRRIKANRGHKKAIIAICKMLLTAIWNVLSKVEPYSAKGYLEPKPA
                     KEEKVLTQSQALDLLRKRGYTIIDSA"
     gene            13325..13576
                     /locus_tag="IVW63_000682"
     CDS             13325..13576
                     /locus_tag="IVW63_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HAP7858981.1"
                     /translation="MKSNQKSGFYTFIKAISSVLECDCIIGPYSMLIKMGFPSTESLD
                     SFINDLSKFGRTNTQIVFSTLVSLMVYQFWNVYHALLLK"
     gene            14118..14276
                     /locus_tag="IVW63_000683"
     CDS             14118..14276
                     /locus_tag="IVW63_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7858982.1"
                     /translation="MNKKQACEFLGIDNNTLDKWIRVYNFPVIKIDGVVRFDVEDIKD
                     FMNTFKKN"
     gene            14348..15574
                     /locus_tag="IVW63_000684"
     CDS             14348..15574
                     /locus_tag="IVW63_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7858983.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGIASEKYQKVFPTRQLAIKA
                     EREMKKKIETVLREENANSLELKGKIKFKDFYESKWLPRYELGQTTRSNRAPSNVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILCYIEFNRTTKIIQCITAPKKMALEEKRIREGNQALSSEELTDWIEAVNNDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFNKNTVRLKYALDKYQRKTHTKGWKDTV
                     IQAPEVVMTLLREWKSAQAEQLLKLKIIQTPDQYLFTYSKPSGEVNCPVHADYLNYRI
                     NAIKKRHPELAQLSPHKLRHTYATIAREGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKSVFEAFQKGLNKCD"
     gene            complement(15663..16055)
                     /gene="rpsI"
                     /locus_tag="IVW63_000685"
     CDS             complement(15663..16055)
                     /gene="rpsI"
                     /locus_tag="IVW63_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAP7858984.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(16071..16514)
                     /gene="rplM"
                     /locus_tag="IVW63_000686"
     CDS             complement(16071..16514)
                     /gene="rplM"
                     /locus_tag="IVW63_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAP7858985.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(17033..17500)
                     /locus_tag="IVW63_000687"
     CDS             complement(17033..17500)
                     /locus_tag="IVW63_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAP7858986.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(17620..19158)
                     /locus_tag="IVW63_000688"
     CDS             complement(17620..19158)
                     /locus_tag="IVW63_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAP7858987.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            19238..19924
                     /locus_tag="IVW63_000689"
     CDS             19238..19924
                     /locus_tag="IVW63_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAP7858988.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(20125..20652)
                     /gene="msrA"
                     /locus_tag="IVW63_000690"
     CDS             complement(20125..20652)
                     /gene="msrA"
                     /locus_tag="IVW63_000690"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP7858989.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(20736..21413)
                     /gene="pgmB"
                     /locus_tag="IVW63_000691"
     CDS             complement(20736..21413)
                     /gene="pgmB"
                     /locus_tag="IVW63_000691"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAP7858990.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(21410..22538)
                     /locus_tag="IVW63_000692"
                     /pseudo
     CDS             complement(21410..22538)
                     /locus_tag="IVW63_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(22538..24721)
                     /locus_tag="IVW63_000693"
     CDS             complement(22538..24721)
                     /locus_tag="IVW63_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAP7858991.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(24718..25743)
                     /locus_tag="IVW63_000694"
     CDS             complement(24718..25743)
                     /locus_tag="IVW63_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP7858992.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTANRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(25788..26615)
                     /locus_tag="IVW63_000695"
     CDS             complement(25788..26615)
                     /locus_tag="IVW63_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP7858993.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(26612..27679)
                     /locus_tag="IVW63_000696"
     CDS             complement(26612..27679)
                     /locus_tag="IVW63_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAP7858994.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(27705..28541)
                     /locus_tag="IVW63_000697"
     CDS             complement(27705..28541)
                     /locus_tag="IVW63_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7858995.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(28538..29407)
                     /locus_tag="IVW63_000698"
     CDS             complement(28538..29407)
                     /locus_tag="IVW63_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7858996.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(29477..30760)
                     /locus_tag="IVW63_000699"
     CDS             complement(29477..30760)
                     /locus_tag="IVW63_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP7858997.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(30774..32459)
                     /locus_tag="IVW63_000700"
     CDS             complement(30774..32459)
                     /locus_tag="IVW63_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAP7858998.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            32734..33759
                     /locus_tag="IVW63_000701"
     CDS             32734..33759
                     /locus_tag="IVW63_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7858999.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(34354..38007)
                     /gene="rpoC"
                     /locus_tag="IVW63_000702"
     CDS             complement(34354..38007)
                     /gene="rpoC"
                     /locus_tag="IVW63_000702"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAP7859000.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(38086..41703)
                     /gene="rpoB"
                     /locus_tag="IVW63_000703"
     CDS             complement(38086..41703)
                     /gene="rpoB"
                     /locus_tag="IVW63_000703"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAP7859001.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            42431..43399
                     /locus_tag="IVW63_000704"
     CDS             42431..43399
                     /locus_tag="IVW63_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7859002.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            43417..44322
                     /locus_tag="IVW63_000705"
     CDS             43417..44322
                     /locus_tag="IVW63_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7859003.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            44319..45125
                     /locus_tag="IVW63_000706"
     CDS             44319..45125
                     /locus_tag="IVW63_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7859004.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            45282..46250
                     /locus_tag="IVW63_000707"
     CDS             45282..46250
                     /locus_tag="IVW63_000707"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAP7859005.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(46567..47091)
                     /locus_tag="IVW63_000708"
     CDS             complement(46567..47091)
                     /locus_tag="IVW63_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HAP7859006.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            47378..>48442
                     /gene="scm"
                     /locus_tag="IVW63_000709"
     CDS             47378..>48442
                     /gene="scm"
                     /locus_tag="IVW63_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAP7859007.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        13795 a        10414 c         8826 g        15407 t
ORIGIN      
        1 acctaactaa acctaactaa actttatgta tctaacagct taataactac ttgcgctgca
       61 agatccattc gtgtttcttt tcattgtgga atttccaaat tcgctcaggt cccgccatca
      121 catttaaata gtaggaagta tacccgtcag gtaccccaac tggatgatag cccttaggaa
      181 cttcgacgac attttgatgc tctaccgtca tcgtttcatc tagtgaacga tcttccgtgt
      241 agacccgctg gaaaacaaat ccctgctctg gatcaagctc atggtaataa gtttcctcta
      301 aaaaagactc atgtggcaga ttctcttgat cgtgcttatg aggaggatag ctggaaaaat
      361 taccgccctc ggtataaact tcgacgacca gcaggctgct ggcagtatcg acattatccg
      421 gtaaaatgtt gtgaacaagt cgtttattct gatagagtcc acgttcttcg acggtattat
      481 cctccgcgcg aatcacactt atcggcaaag cttttttcgc tggtgaatag caaagcgcca
      541 atcggacatt gtctgtagtt gccacaagtt caaacgaatg ctccgccgga agataaatac
      601 tgtcggttgg aattttttca aaaacagatt ctcgtgttcc taaatcttca taccaagtgt
      661 ctgctgcttt aaccttaatt tttccagtca aaatgacgat acagacctcc tgttgactgc
      721 cggtttcctt gtaagaagct cccttttcca gctccaaaat ctgaaattcg atataactca
      781 aagcagaatt agactgccga atattttgga tttgttttac tccaggtgcc agttctttgt
      841 ttaatggttg atgcttcaat gtcttttcca atcaatccac tccttatttt caatcacaaa
      901 aagcaatatt taatactttc tgatagtggc aagtttcgct tgtttggctt tgtaagcctc
      961 ctgcatggct gctttacccg atacctctga gataccgacg ttccaccagc tgccgtcgta
     1021 gccttctgtc atggttttag gaagtacctt tatctcaatc aacgtcgatc gcgtttgctt
     1081 cttcgcatcc tcgaccgctg cttgtaattc tgcaatcgag cttacacgat acgtttttgc
     1141 accatagcct tcagcaactt tggcgtaatc gatgttcatg atctcgtcct tggtatttct
     1201 gaattcggtt ccttggctag ctccgccatt atccatctgt aaattattga tacagccgaa
     1261 accagaatta tcgaaaagta caatgttgat ttttttatca tattgcaaac tagaaaccag
     1321 ctcgctatgc aacatcaaga aactgccatc gcctactaag gcatagacct cttgttctgg
     1381 tcgagccatt cttacgccca tcgcaccagc gatttcatag cccatacaag aataaccgta
     1441 ttccaaatga taggtattct ccttcacagg gttccataag cgctgcatat cccccggcaa
     1501 tgaaccggct gaaccgatca cgatcgcatc ctcatcaaca aaatcattta aatgaatgaa
     1561 gacctctgtt tgcgtcaaat tcgtagccaa cgcatcagca tattcattca agatttcttg
     1621 agaaaaatga tctttgattt ctggcgtaaa atctttacgc ttaaaatgcg cggcttttaa
     1681 ccgatttcgc tcactgatcc attcttcctt cagttcatcg atcttctcgc cataggcggt
     1741 ttggtaacct tcgatcattg gggcaagctg ctccaaggtc gctttcgcat caccaaccac
     1801 ttgaaaggct tccagcttag cggcctgttg tctgcttacg ttaatattca tcattttcgc
     1861 ttgttcaaaa ttaaaaatac ttttagaagc tgaggtaaaa tcagtgtagc gtgtgccgat
     1921 ccctatgatc agatccgctt gctgcacagc tttattagca gccgaagttc ccaaaatccc
     1981 cattccgccg agattgtttt taaaatccca cgaaacagtc gatttacctg cgtgcgtttc
     2041 aactagcgga atctgacaat ctcttgagat ttgctcaaga atctcaccag cctccgaata
     2101 tttgcagccg cctcctacga tgatgacagg tcgtttactg gcctttattc gttgactcgc
     2161 ttcagcaagc tcacgagcgg tcggaatcct gcgatcaata taatgtactc tttttttgaa
     2221 aaattcctcc ggataggcat aggcttctgc ctccacgtcc tgcggcaaac aaatcgttgc
     2281 cggacccatc gttgccgggt tcgtcatgac ttcaaaggcc cgcaataacg cggacatcaa
     2341 ctgctctggt cgattgatgc ggtcccagta gcgagaaacc gcttgaaatg catcatttgt
     2401 cgaaaaggct acactgcttg catgttccag ctgctgcaag accggatcag gctgacgtgt
     2461 agcaaacgta tccgccggta aaaaaagtac ggggatatta tttgcgaatg ccgtacccgc
     2521 tgctgttaac agattggccg cgcccggtcc aacagatgtt gatacggcaa aaattttctt
     2581 gcgtaaattc tgtctggcaa aggcagtagc cgcatgggcc attccctgct cattttttcc
     2641 gctataactt ttcaaatgtc cgggctctaa ttccagcgcc tgaccgatcc ccaaaacatt
     2701 tccgtgacca tagacatgaa agataccttc aacataaggc gtttctttgc cgtcgatgct
     2761 gatgtattgt tgattcaaaa attttagtaa tgcttgtgct gttgttaaac aaaccgtctt
     2821 ttccattttt ttcaccttaa atccgagcga tcatttcgcc gtatatttct ttctccaatg
     2881 taataaaatc ttttacctcc tgagtcgtcg gtaaagaatc tgaacagtta ttgcttttga
     2941 ccatcattga tgcttccgct gagccaaact ctaaacaatc gatgatctcc cagccttcga
     3001 ataaaccgta taagaaaccc gagccgtaac catctccgcc gccaaagcct ttgcgtgctt
     3061 ccaccggaaa cggcttgatt gaaaactgct gctgatcggc cgtataagca gtcgatcctt
     3121 tcattccatg tttgattacg acaatctcag caccacaact gtgccaaaaa gcagcgcttt
     3181 cattatctga catgttaggc tggatcaact tctcagttag atcgaactct tctcttgaac
     3241 ccatgataat gtctgattcc ttagcaatca tcgaatagta aattgaaata tcatcgttgt
     3301 tcttccagtt ataagcacgg taatcaatat caaaaataat tttgacatta ttccttttcg
     3361 ccagcatcac tgccttgatt acggcttctc tggacgggct ctctgctagt gcagttcctg
     3421 agattaatag tgcttttgac cgtttcaagt agtcctcatc aatatcctca acgctaagct
     3481 gcaggtctgc ggcttgattt cgatacatca aaatattact ttcctttgat gagagcattt
     3541 cggtaaaagt cagccccagc ttttcaccat gctgcgcttt gctgatctga gacgtatcga
     3601 tgccttgttc attgaaataa tcgatcacat attcgccaaa ctgatcgtcc gagactgttc
     3661 cgataaaacc agctttcatg ccatgtttag taacacccac agcaatattg gcaggagatc
     3721 cgcccacaaa tttttcaaac atatggacct ttttcaatgg tttaaactct tctttgactt
     3781 gatcattgta ggcaggatta aaatcaatag cgactcttcc taaaagcagc aagtcaaatt
     3841 cttttgattg gtcaaacttt atataactca atatatccac ctctttatcc gttcttctat
     3901 ttctgaggca agtatagcac gccaaaacaa agcgtgcaat atttatttta gaacgcaata
     3961 ttgcgtgctg tttgaaaatg acggcaaaaa aaacgtgaat cgccttacat cacgattcac
     4021 gcctagatta aatattgtat tttgtcttaa taattatatc agtaaatagc gcatcttttg
     4081 taaccgtttt attattttgc agctgattcg ctaacatcag taatgaacga tagccttgaa
     4141 caaatccatc ttgatcgatt agaaaatcaa cctgatcgtt tttcagcatc tcgatattgt
     4201 tcttagtcaa atcataaatg attacaaagg gccgcttgct ttcatcgatt ttttccaacg
     4261 ctcgggcaat tcccgcttgt ccgccagaaa agacgactac gccatctaag tttgaataat
     4321 tctccaaggt gttgcttaaa atcttttcaa cctcagcact cgaatcaaag ctgctctgaa
     4381 cacccgtcag ctccagttca ggaaacgact ctttcaattc ttcaacaaag cctgccaccc
     4441 gtaagctgtt gacgctattt ccaaagtagc cggtaatcgc tagaaccttg ccctttcctt
     4501 ttgtcagcat acctaacaat cccgcagccg tttttccgct tttgaagttg tccatcccaa
     4561 caaaacactg tcgattcgta ccaagaatat ccgaattaaa ggtaatgatg aggatgcctt
     4621 gatcggtcaa ttgattaatt ttttctctga taccatcact atctactggc atgatcgcga
     4681 tcccttttac tccaagctcc accaatcgat ccaacgcctg cagctgggcc gcttcatcga
     4741 ccccgtctac ctcttctaaa aaacaatcaa tgtttcgctt ttttaaatcc ccgataatag
     4801 attccagacc tgatcggatc ggaatcataa aagaagattt cgccaattga gtgacaatcc
     4861 ccagcttgag cgttgtctct tttatgacct tctttttctt tggaacatag ttcatttcct
     4921 tggcgattgc tctgattctt tctgcaacct caggattgat ccttcctcga tcgttcaatg
     4981 cccgatccac tgtccccctt gacactcctg ctttctcagc tatttcttta attgtacccg
     5041 ccatcttgcc tctccttttt tcctattgtg tttattttat cacaaaactt aagaaaacca
     5101 ccggagaatg aattctccgg tggacttttt gtatgattaa ccttcttatt gaacatcact
     5161 gatcttaaac tctattccaa gggcgtttct ataatattct ggatacatct ccttcccaca
     5221 tttttcacag gtaaattggg gaggattgtt cggatcattt gcaatatctg catcatctaa
     5281 aaattttact acatccattg ggattgattc tttttcacca caacttagac atataaattt
     5341 cacgttggcg ttcccaatcc cagcgaattg ctttaaaagt tttttctttt tcttcttcat
     5401 actgttgcct gaattctttt tggtcaattt ttcgattctc ctctcgcata aaccgctttg
     5461 catggttatc tttcgcatat ttaataacta accgtccatt tttgcgcaca ctcatcccaa
     5521 cgaattcata gtactcaccg caacaagaac attctaaggg attttcacca aattcttcgg
     5581 ttattctttc ttcccaggat tttggtctta aggcctcatt cagattgata aacagctttt
     5641 ttactcgttt ctgatactcc ttcatgacct ttttcattaa tgttttgatt ctacgactat
     5701 agattccata gcgacgaatc gttttgaaat tcttattttg aatatggcga atcagtgcag
     5761 ctatgaattc gtctatactc atggtcatcg tctctttagt attcgttcgt ttgtccatgt
     5821 agttgaacat gacagtgtcg ccatcataca ttaagattcg gcttaatgcg atcgggccac
     5881 gcttcatata acgactgatg tattggagta gtgactttag atttgtcctg ctccttttag
     5941 gagcatttac gtaaaaccct tctccattgt tcttgtacgc agcttgtaat cttgattgaa
     6001 ctctttgctt gtcccactca cctaacgttc gtctaattag tttcaataca gcatttttcc
     6061 agtattttct taacatagaa aaaggtaaat aatcgtattc ttcccaactt ccatctcttg
     6121 ttaagccacc catagtaaca accatatgaa catgcggatt aaattctagt tttgatccaa
     6181 aggtgtggat tgtagctact atacctgcct tcacctttct tttctcaaaa taggcaagaa
     6241 taatttttgc ggcttcatcc attagtcctt tcagtaagga atctcgatag ttttccatca
     6301 taaagatttc ccgtaacccc tcatcgatcg taaagattac gtgccgatgt gtcactttaa
     6361 acatatcatt cgccacaacc gctgaccacc tttggctttc acctgttgca cacgttggac
     6421 agaactttcc acgacatttc aagggaacaa actttgtttg atgacatccc tcgcagacaa
     6481 acagtcggta tcctttttga atatctccac aatatctaaa cttgtttact tcccgtttga
     6541 cgactagccg aatctttcgc ccgtatttct caacaaagtt atcccaatta tggtgttcgt
     6601 caaaaaagat tgcttcgaga atattcgctt tcatagtaat attttacttg ttcaaaaaca
     6661 aaatgaaaag ggctaaaaga ctggtagtgc agccttttta gcccttaact ttttatactt
     6721 tctttactgt ctaaaaaata tgcggcgcac agaacgcgcc gcatatcgga ctaagtttta
     6781 ttcaaatttg tcttcgccaa cacaatttga cgaagagcct tttctttcag gaagacttcg
     6841 gtaattttta ggagttctac ctattctttt aaccgtttat tctctttttc taagcgtgta
     6901 atttcatttc tgcgaatgga tttcatgact tcctctaccg agaaaagtac gttatccata
     6961 tttttcaact tcttgaactc atcaatacac gctattagag cgagcttcta gctatagact
     7021 aacttcttta acagaaaacc cttcttccgt taccagtttt acagcggtaa ttttaaatat
     7081 ttcatcaaat gaacgtcttg gcataatcca gatcttcgct ttctcttaat ttggtgtcaa
     7141 ttttagtata acccgtccaa cttatttttt aactaagtgc ccggtttttc ttgacaactc
     7201 cacccaaaag ttagattttt tggtctaagt tttagggtcg cttcattact agaattcaac
     7261 aagagatgtt ttttatttta tttaaattat ggggtcagtt tccatttgat tacaaacttc
     7321 tttgttttct ttttttaaac gcaataataa aggttttaat ttcagccttt ttaattagaa
     7381 aatcaatttt cccaaattat tttctttagc tttcttaacg atttctgtcg caactaccac
     7441 atctaataca gccgaaccaa ctgttttgaa gatcgtgatt tgttctccac ttgtccgacc
     7501 gatcaattct tcattgatca gttggcctag ttccccatga tagctgtctc tttgaatata
     7561 cccatcttgc agcggtgaaa tgaagtcccc agcttctttt agaacaccgt ccatggtatc
     7621 aaaaataaca acatctgcgg ctttgattat ttctcgtgga atttcacaca tttccggtgt
     7681 gtaagcaccg actccattga tgtgcgcacc ttttttgacc cactcagcag agaatgtcgc
     7741 acgttttgaa gtggtcacac ttgtaatgat gtctgctcct tcaacgcatt cttgactggt
     7801 ttttgttggg cgcatcgtta cagaaaattg ttgcatcatt ttttcagcaa attggctggc
     7861 acgctcaaaa tcaatatcaa aaatccgaac ttcttctaat ttacgaacgg tcaacattgc
     7921 ttctaattgt gactgtgctt gtccgccggt tccaatcagc gcgccaattt tagcatcttc
     7981 tcttgcaaga agttctgttg ctgctccttg aacagcgcct gttcttaatt gtgtcaaata
     8041 agtaccatcc aaacaagcgg ataccatacc cgtttctgga tccaatacga tcatcgttgc
     8101 tggtacactt ggtaagtttt tcttgatgtt ttcaggatac acggaaacga ttttgacacc
     8161 tagcgcgcct tcgccacctt ctacataagc aggcatatat aagctttgtc cgttgctttt
     8221 tggcacatcg atattggtgc gaagaggcac acttgccttt cctgctgaat acaatgacag
     8281 tgcttttttg tccgcatcga tggcttctct cattgaaaaa cttttgataa tatcttcttt
     8341 tttaagaaat aacatttgaa tcgctcctta attagctgct gtaacttttt ttaattgact
     8401 gcccaacatc gtatatgcac tgtatagtaa gaccaaaatc acgatccatt tcaggatata
     8461 ggtatctaaa gatttgacta ggaatacagc gaccaatacc cccaatacac cgaaggttga
     8521 agtaaaaagt gtgatttttc tgctgtattc attaaattta atgaattgaa cactgccgat
     8581 cggtactgag aaggtacaag cccccatcat aataggaaag gctgcaactg gattcaagcc
     8641 tagcaagtag acagttacca tcgttaacgc ataagaacca atgccgatat tgttcaatgc
     8701 accatagaca aagagtaaaa atcctgccaa gattaatttt ccgccataca attcactggc
     8761 tgttccgttt gatggaatcc agttcatttg tcctgcaaaa atcaacaatg cagcaatgac
     8821 caatcctatg ccgacaaaca gtttgatcgt tttctctggt aacttcacga caaatcttgg
     8881 tcctaaatat gcaccgataa tttggcagat aatacaaaca gctagtgtct tgatccctac
     8941 gttgatggca gtgatgtaag acaatgccat gacggctacc ggtactacac attgggtatt
     9001 caacgttccg ggtagttttt tcatgctgac ccatttcaac tttggataaa ggacggttcc
     9061 gatagcaaag tcggaaacgc caaatgttga aagaaagaag atgataaatg acgtgaaggg
     9121 caacagacgc atatcccctg gttcttcttt gaaattttgt ttgtttttga aaaggtctct
     9181 tagaaagtaa ataataaaat atagattgat tgcgacaatt agtgtcagca aaatattccg
     9241 aatcataaaa aattcctcct actagtaaat ctttctgatt ccctcaaagc cctcaccata
     9301 ttttgcttta agttcttcag gagattctgc aatcactttt agtgtatatg catcatgttt
     9361 gacatattct tttgctagat tgaccatggc gtggtttttt gtccaagtga catcggttga
     9421 ttgcagttct tcgttaatgg taccaaacac gacttcttgc tcatcggcga cgatgttgat
     9481 ccatcttgct ccaaagtcag caagtttgtc tgtttcaaaa ccatgaatat aatacttttc
     9541 taagggaaga tcatattcat gggtagaact gaataaaatc agtacaaact tatcaactct
     9601 tttttcagct tgctgcaatg cctttagtag tgaatccgtg aaattctcat gccaaacttg
     9661 aatgagcaaa ctttcttttg cgtttttcac caaatgctct actttatcca gaacatactc
     9721 gataccatca actttccaca gcatttcttc ttcatctttt tctttgatca tccctagatt
     9781 cttggtaaga aaagaaagat catttttaac acttttttct aatttctcta aaaactcatt
     9841 tgccgagatg gcatgataaa gtttaggttc tgatttatta acgacaatca aattcttttt
     9901 taatagtttt tccaaaatat tatatacttt cgagcgtggc acacctgaga ttttacttac
     9961 ttcatatcct gtaagattac ctttttctaa tagtgtggta tacactcttg tctccatctc
    10021 tgaaaaatca tattttttca tgatttgaat aatcgtttcc attgattaat cctcacttta
    10081 tttttagtag ctactacggt aacaactata aattcttttt gattatctgt caagagttag
    10141 ttcaataaca cacatataat aattagctta aaaacaatct ttttattaaa aagaaacatt
    10201 ataatatgaa tgtttgtgaa aaaataatac aacttagtca ttctttacaa cgatttatag
    10261 aaaaacaacc tctttaaata taaaaggtac gggttactga ttacttgtaa atctttacgt
    10321 tccagtttta ttctttctaa aaaatatact cacttctttt cttagacttc tttttttgat
    10381 tctcctcttt atggtcttgt ccttttttgc cttcaaaata tttaaataaa cccctttcaa
    10441 aagcatttct aggttttgga caataaggaa tgactttttt cttcatataa atacctcatt
    10501 taactatttg atatcatcac attatcaaaa aaaataggtt ttttattaaa actatcttga
    10561 cctttcggga gatttcactg tgatttattt ttattcccat acttttttcg ttggtcactt
    10621 tcgtatacct aatctaagcg atcatcggcg acggtgcttt tacaacgaat ggcaggacaa
    10681 aacaaggggc ggaaaaactt ttttgcctat ttcataaaaa actttttcct acagcaatcc
    10741 cttgttttgt cctaccacac gttgtgaacc caaagcacgc cgacgaacgc ttagctatac
    10801 gaaaatgacc tccaaaaaca aaaaagtgag gtgaatagaa acaaaaagaa attgaaatct
    10861 cccaaaatgt cgtccgcctc ggagacaact tgctgctgaa aatggttggt taattcattt
    10921 aagtattaaa taagataaat catcaaatta atcggaaaaa tagcatgatt ggccttatca
    10981 aaaataaact gtaaaaactt atatttctat gagtggtgga acaatgctaa taccaaatta
    11041 atttatcgat tacccacctg cacaaaccaa agatagcatt attaggaaac gaatcaatca
    11101 gcgaatccag cattataatg aggatactaa aaataaagtt ttcataatta taaatccgcc
    11161 ttcctacgaa aggcaccaat gaggtgatga aaaccttaga gcgctttctt tcttttttta
    11221 ttccgtgtta ccctttcctt gcaggtccct ggtacactac agaacccgag gaggtgagtg
    11281 gcggggctgt atagcggcaa ccccgcataa ttatatggtg tcggtcatcc gttaaggcat
    11341 caatgaatgg cgcaaacccg tagcccgtaa acttatctct tccgaagttg actcgatttc
    11401 gccggatgac cagtccctac caaacctgta ctattttttt acaggaggtt gctatgttca
    11461 aaatctttcg taaaaattgt tgtggcttgg atgtccacaa aacgtggatc tatgcgtgta
    11521 tcggaatcac agatgcgaat ggtcgtacag tgtataagca agctcgcttc tcttccttta
    11581 caaaaggtct caatgaatta gctgaatggc ttgctaaata caactgtaag gatgtgtgtt
    11641 tggaatcttc cggtaaattt tggattcctg tttttaatat tcttgaaaaa acttgttttg
    11701 tcacactggc tcatccgaag tacaccaaac cccagaaagg aaataaaaca gatcgcaaag
    11761 atgcaaaaat ggatttgtga tctctttatg tgcgacatga tcaaacccag ttttattcct
    11821 ggtcttgaaa tccgccagct tcgtgatcta atgcgttatc ggacgaaact gaccaacatg
    11881 aaaacaagtg aaaagaatcg tgctttaaac tgcttaaccg tttctaatct gaaactagat
    11941 gatgttttta gtgatgtgtt cggaaaatca tccacttcta tcatccaata cttgttagaa
    12001 catcccggtg aatcatttga tgttcgacca tttatccatg cccgttgtaa aactcccgtt
    12061 gaagaaatcc aagcggcagt tgagggggcg atttctgtac ctcaagcgat taagcttcgc
    12121 caatgcctca accatattaa cgagattgag aagcatcgag aagagatcaa tctagagatt
    12181 caagctcttg cagaaccctt ctcccctgtt ttggaactac ttcgtaccat accgggctta
    12241 gacactcagc caataacagc gattgcgatt ctttcagaaa taggaccgga tatgtccgtg
    12301 tttccaactt cgaaacactt tatttcttgg gctggatgct gtccaagaaa cgatcgcagt
    12361 gcccgacgaa caaaatcaac acgtatctct cgtgcagggc agtcgttgaa accgctactt
    12421 gtacagattg ccaatgctct tctcagatcc aaagaacatc cagaatttaa aaatcgctat
    12481 cgtagaatca aagcgaatcg tggacacaag aaagctatca ttgctatttg taagatgctc
    12541 ctgaccgcta tctggaatgt cttatcaaag gtggaaccct attctgctaa aggatatctg
    12601 gagccaaaac ctgcgaaaga agagaaagtt ctgacgcaat cccaagctct ggacctttta
    12661 agaaaacgcg gatataccat tatagatagt gcttaaacca aagttacgtt gattcttcct
    12721 aaatagactc gttgtcttcc atttcaaaaa ttttgaaaac ggtaggctta tttagtgtac
    12781 cgttcttcag gtatcttcaa atagatttat tttcaaactt atttcctttc ttcttttact
    12841 ctcctatagc ttagcattta agtgggcact cgtgtcacct tgctagatag ctatgaatgc
    12901 cgtaataagc ctcctagtat ataggcagac tgccaattat aactgattca atccacatta
    12961 tgataaaatc caccttttcg tttcatatgt gttgaaatat cacatatgtc aaaagtgcac
    13021 gagtcttttc attcagtgct ttgtaaatac tcaaaattat tccttttcac tttaaaaaaa
    13081 agataattag tacaaaatca gaaatgagga aagtattagg atggactaga aaggagttgt
    13141 tgaatttgtt gcaacagatt ggtcatttat caattaaaaa ttaggtgaag ttttattcat
    13201 cactgcagct gctgtttccc agagaataaa acgtctagaa gaaactggtc agttactgta
    13261 ttatcaagca gcaattgact acgaacaagc ttgattacta accaaagcgt ttatccacct
    13321 gttgattaaa tcaaatcaaa aatcaggttt ttatacgttc ataaaagcaa tctccagtgt
    13381 actcgaatgt gactgtatca taggtcctta ttcgatgtta atcaaaatgg ggtttccttc
    13441 taccgaatca ttggacagtt ttatcaatga tttatcaaag tttggacgaa ccaacaccca
    13501 aatcgttttc tcgactcttg tttccttaat ggtttatcag ttctggaatg tttatcatgc
    13561 gcttttatta aaatagaaaa gagctttttt catgcgacaa agcagtgatc atttattggc
    13621 acatgcaatc tttgtggatc cattttttga aaatacgata tttagttttg acccaaaaat
    13681 ctttaaatac gtatttgata atttatctta acaaccagat aattttattc agcaccgtat
    13741 tatctatatt gaattctcgg aatcaagata aatttttttc cgtttttgtt tcttttttaa
    13801 tcttcttctt gttattaata gtgattagga tgatattcct atattgatct ttgataatta
    13861 gatataattt ttgaataacg ttccctgcta ttcgagctag aaatacaagt acgccatgac
    13921 ctagttagcg acaactactt agagatttct tttgttctgg gacaacaaaa tgccatgaca
    13981 atagcagtaa ataatgatac ttccgtaagg ctcgccgtaa actggggaga ggtgaaattc
    14041 ctatgtgctt acccaaagcg gttcaaaaat tttaaactat tattttagga gatgatttta
    14101 taaaatcgaa agcctacttg aataaaaaac aagcctgtga atttctagga attgataata
    14161 atactttaga taagtggatt cgtgtatata attttccagt aataaaaatt gatggcgtag
    14221 ttcgctttga cgtagaggat atcaaagatt tcatgaatac attcaaaaaa aattgaaatt
    14281 ttcttctcgt cacatatact ataaatagcg aaatgtactg ccttactttt taaaggagtg
    14341 aggaagtttg cctacaaagc tttcaaatgg gaaatataaa actaatctga ggtatccaaa
    14401 aaaattcaga gaaatcactg gaattgcatc agagaagtat caaaaagtat ttccaactag
    14461 gcaattagct attaaggccg aaagggaaat gaaaaagaag attgaaacag ttttaagaga
    14521 ggagaatgca aactcactag aattgaaagg aaaaataaaa tttaaagatt tttatgaatc
    14581 aaaatggctt cctagatatg aactaggtca aactactagg tcaaacaggg ctccaagtaa
    14641 tgtaacaatt agtaatacta aggatatatt ccgattgcac atccttccaa tgtttggtga
    14701 atatgcaatg aattatctga attcaaatac tgagataata tcagatgaat taacaaagaa
    14761 atcgaaagaa tacgcaaata taaaaattat caaaggctat gttcgctcta tgtttgatat
    14821 tgccgaaata ctatgttata tcgaattcaa ccgaactacc aaaattattc aatgtattac
    14881 cgcgcctaag aaaatggctt tagaagaaaa aaggataagg gaagggaatc aagcattatc
    14941 atcagaagag ctgactgatt ggatagaagc agtaaacaat gacttaaata atcacttgct
    15001 tacacttcac gattacacac ttttcatgct taccttatat ctaggtgata gaaaaagtga
    15061 gacttatgct ctgcaatgga aatatattga ttttaataaa aatacggttc gtctcaaata
    15121 tgctttagat aaatatcaaa gaaagacaca tacaaaaggt tggaaagaca ccgttattca
    15181 ggcaccagaa gttgtgatga cattattaag agaatggaaa tcagctcagg ctgaacaatt
    15241 gttgaaacta aaaattatac aaacacctga ccagtacctc tttacctatt ccaaaccttc
    15301 tggagaagta aattgtcctg ttcacgctga ctacttaaac tatcgaatca atgcaataaa
    15361 aaaaaggcat cctgaattgg ctcaattatc tccacacaaa cttcgtcata cctatgcaac
    15421 tatagctagg gaaggtggag caaatatgaa tcaaatctct aatgctttaa cgcactcgga
    15481 tatttctact acaaaaatat acgtgaacac acctgacgta gttgataaat ctgtttttga
    15541 agcatttcaa aaaggattga ataagtgtga ttaacatgtg ttctcaaatg tgttcttatt
    15601 ataaaaaaag acactttcca aataattgaa aagtgtcctg aaatattgat ataaaaagaa
    15661 tattaacgtt ttgagaattg tgaagcttta cgagcttttt taagacctgg ttttttacgt
    15721 tcgaccatac gtgcgtcacg agtaagtaag ccagcacgtt taagagctaa acggaagtca
    15781 ggatcaactt ctagcaatgc acgagcgata ccatgacgga tagctcctga ttgtccagcg
    15841 tatcctccgc cgtttacgtt aacaaatacg tcatatgcgc cttttgtttc agtaacagcg
    15901 aaaggttgat tgattacttc acgcaagtca gcatgtggaa tgtattcttc aacatctttt
    15961 ttatttacag taattttgcc agttcctggt actagacgta cgcgagcaac tgcgttttta
    16021 cgacggcctg tgccgatata ttgaacttgt gccaatgaaa ttccctccta ttagattaag
    16081 tttgtgatgt ctaaaacttc tggttgttgt gctgcatgtg gatgttctgc tccaccgtat
    16141 acgttcaatt ttgtaaattg tttgcggcct aaagtgtttt taggaagcat accttttaca
    16201 gaagtttcga tcaaacgacg agaattttta gcacgcaatt cgccagcagt gattgatttc
    16261 aatcctcctg ggtagttgct gtgacggtaa taaattttgt cagtcgcttt tttacctgtt
    16321 aatttcactt tgtctgcatt gatgacgatg acgaaatcgc cagtatccaa atgaggtgtg
    16381 aaagttggtt tatttttacc acgtagtaca gatgcaacaa ctgttgaaag acgtcccaat
    16441 ggaacatcag ttgcgtctac tacataccat ttacgttcta cttcgcctgg tttggccata
    16501 tatgttgtac gcacgttatt ttcctccaat ttaagttctg atgtttgaca tacacttcga
    16561 gtttccgggg ctctttgtgg ggcaaacaat accatttaac atattacccg ctaatctagt
    16621 caatgtcaac gtttttctgc ttgattgaaa aatttatatg aaactttact tcttttcttt
    16681 cttttatata aaagggtcgt ttcctgtcaa aatgaaaaac aaaaagaggc tgtgacaaaa
    16741 gtcttgtcac aaccccttat tttgaataaa cggtgttctc ctgccaactc ctcggtcaca
    16801 agtcacaata tccataaaac ataagaagct gttttttaaa attgtttctt gtgactcgga
    16861 gctgaacggc aggcttacaa cctcttggta aacggtgttc aatcagctga ccctcggtat
    16921 tagctcaaaa aacggcaaaa tatgaggaac tattttgacg tttgtttctc taatactcag
    16981 gtcaaaacgc tgatttcaca acctcttttt cggtcaagtt caacaacagt ttttacgcgt
    17041 cgatctctgg cgctttgccc aaatgagctt ggatcatcca gatacgtttt tctgtggctg
    17101 ttttgaattc gataaagata tcttgtgttg gatcgtcgcc ttcttctcca gaaacttcga
    17161 ttcctttttg gtaaagatct gctagataac gatagcctgc aacaagtgtt tccaaacgtt
    17221 ctggaatagt acgatcccag cggccaattt catcagggat ttttgtgtta tctgcaaatt
    17281 cacgcaatgt agaataaggt gaaccgtcta atgtgatcaa gcgttcggat acttcatcta
    17341 actgagcgtt caaatcatcc atgaactcat ccatcattgg gtgcaatgta aggaaacctg
    17401 gtcctctcat gtaccaatgt gtttggtgaa caacaacaga catttggctt agatctgcaa
    17461 ctaattgatt taatacttct ttggtttgtt ggaatttcat ctttcttgcc tcctaacatt
    17521 ttcttacact taaaataata gtagactttc aatgaaaagt acaacaaaat catttacctg
    17581 agaacgattt tcagttcgct tttttatccg taaagccaat catttttcag aatcagctaa
    17641 ttcttctcgc agttgagcaa attgctgata agtctgtgct aaatgctttt gtgtcgaaac
    17701 aaataatgga tagattttct gatatttttt atgatcagtt tcttgtactc caacttgctc
    17761 tttcaattct atcaattcct gtgcttcact gatactttgg atctttccga tgcttctcca
    17821 gcctaaaatc acagctccta atgcggatgc ttctgtgaca gtagggaaaa caagcgggta
    17881 acccagtaca tcagccatca tctgacgaaa aatcggagat tgagcaaacc cgcctgtagc
    17941 acggatctct gtgagctgat tttcctggca aactcctttt aaaatccgat aaaggttgag
    18001 acagatccct tctagaatcg ccttcatcat ttctttttct gtatgttgcc gctgtaaacc
    18061 gataaaactg ccaaacgcat ctgcgtccca aagcggtgct cgctcaccaa gtaaataggg
    18121 atgaaaaatc agaccattgg cacccgctgg cacaaaagcg atagccgaaa gcagtgcatc
    18181 atatggattt tctccttttt ctttagcaga ttgaacgact tcctgtaaaa atgtatgccc
    18241 tgcccaatca aagatgccag caccattgct agtcgctcct cccactaccc aatgtttctg
    18301 atccagaaca taacaaaacg tctccatttc tggatggaac tgaggctgag tagtaataaa
    18361 acgaagtgct ccgctcgttc ctacggtcaa agcggcgatc gtatcaccaa aagcacctaa
    18421 ccctagatta gaaagcggcc cgtctgcccc tcccaaaaca aatgatatat catttggcaa
    18481 acctagttct gctgctgttt ttgatggtag acctgttact tgataggtgg aaggaaagac
    18541 ttgcggcaat tgctctattc gaatgttcaa gtagtcaagc acttcttctg cccattggaa
    18601 ttcatggata tcaaaatatc cagttcctga agctgttccg tagtcgctga tcagttcgcc
    18661 aaacaatcta taaaagatat agtctttgat accgacaaaa taagcagttt ttttgaataa
    18721 ttcaggttgg ctgttttgca gccacttgat tttgttcaat ggtgtcattg gatgaatcgg
    18781 cgtcccagtc tgccgataaa attctttgcc aagcacggta tatttcagtt tttctgcttc
    18841 gtccgctgct cggttatctg cccaagtgat cattcgagat aacggtgttt tctcttcatc
    18901 caacaatatc aggccatgca tcgcagagga gaaggagaca aattgaatga ttgtgtctga
    18961 aggcaactgt ttaattactt cttttataac ggtgcagaca ccttgaaaga tcaattcctg
    19021 atcttgttct gccatccctt gtgtttcttg gatcaaaggg tagcgaaaat aagcggatgc
    19081 tgcttcttgg gcttcatctg tgaaagcaac tgctttggtt tgtgtggttc cgatatctaa
    19141 tccgattgaa acgttcattt tttcacctca aattttatgt atgtacaaaa atttagttta
    19201 agcttgcgta tcttggtttt gaaaaggggg agatggcgtg ttactttatt ttatcattgg
    19261 ttgctgtatc ggatcatttt tatgtttaac cgcccagcgg attccgttag gtcactctat
    19321 tatttatcct agatctcatt gtgtcaaatg ctgtcgttcg ctttcttggt atgaattgat
    19381 tccgattctc tcgatcatcg tccaacgatt tcgctgccgc tattgcaggt gtcggttgcc
    19441 cttctactat ttgttggcag aagccttatg tggtggtctt tttgcctggt tctttacttt
    19501 ttcttccgca agaaattttt cgacgttcat atggatgctt tcggctttgc tattttcgtt
    19561 gatggattta ttttacttca tggtccattc tcacacgcta ttctgttctt gggcaatttt
    19621 atggattttt tggttgcagg ccggcgtctt ccaatggcaa agtgtgctgt taacgtttat
    19681 cgtaggcggt gtgtgccttc gctatggtca atcctatctc ggagctggcg atactctgtt
    19741 gatgctttct tggagtggtg gcttgtctct agaagagttg cttcagatct tgtttcttgc
    19801 tagtctgttt ggaatatccg ttttttctgt ttactttatc tgtcataaaa aaaagttgga
    19861 aaagctgcct ttcattcctt ttttgagcag tgcgttgctg attgtccttc atcttaggta
    19921 ttgaaaaaag gttgtgacaa acgacttgtc acaacctctg atatatagtg ttctcttacc
    19981 aaatccttgt gacttggagc taggcgacag gttcacaacc tctccactaa atggtgttca
    20041 atcagctgac cctcagtatt agctcaaaat gctggtttta caacctctga tatacggtgt
    20101 tccataagta gctttttcgg cttcttattt cttgacgccc caatgtcgac gaaggaaacc
    20161 tgcacgtcca gaaccttctc gataaagatt gtaatggagc ttgtttttct tgtaataatc
    20221 ctgatggtaa tcttctgcag gataaaattc gcttcttggt tcgatttttg tcacgattgg
    20281 cttatcgaat cgcccgctgt cttgcaatgc ttgttttgaa cgctctgcaa tatttcgttc
    20341 ttcttcatca ttatagtaga tcactggacg ataagaatca ccgcgatcag cgaactgtcc
    20401 taatgcgtca gtcggatcgg tttgctgcca atagatttcc accaactgat cataagaaat
    20461 aacttctgga tcatattcga tctctactgc ttctgtatgc cctgttgtgc ctgttgttac
    20521 ttgttcataa gttggatttg gtacatgccc gccagtataa ccggatgtca cagaaatgat
    20581 ccctggctgc tcttcaaatg gtttgaccat acaccaaaag catccgcctg cgaaaactgc
    20641 tttttttgtc atataaaatc cccctttttt ctcatcatac cttgatttcc aaaaggagga
    20701 taacgttttg cttgtgacag aaaaaacgga aactattata tacgtgatac ggcttctgat
    20761 aaatgccaaa acgaacgtac ttgatcaaaa acggttaaat caggaatcac atattcagca
    20821 gaaggaagat ttatgttttc acctattccc aatacatgca tgttaccagc caaagctgct
    20881 tgacaaccag cttctgaatc ttcaatgacc aagcatgcat ttggcggtac attcaattgc
    20941 tgtgctcctt tgagaaaaac ttctggatca ggttttgctt ttgatacttg cgtgccgtca
    21001 ataaggacat caaaataact tgtcaaattc gttttttcta aaatgaggcg tgcatttttg
    21061 cttgctgatc ccaatccgat cttgatgttt gtttttttca agtactcaag aacagctatt
    21121 gcaccaggca aaacggatgt ttcatccatt ttttgaatcg cttgaagata tagattgttt
    21181 ttttgctcag caaaggctga tttctctttt tctgagaatt tctgttccat ttttccaaat
    21241 gacagcaatc gctctagtga ctcggttctg gatattcctt tcagttgctc gttttctttc
    21301 tcagtgaatg gaatggacag ctggttagct aaaaccagcc acgcttcgta atgataacga
    21361 gctgtgtcta caagaacgcc atctaaatcg aatagtgctg ctttgatttt catcgattac
    21421 ctccttgaaa atgaacgact tgaagtaaag atgcgatgtt tttagctgtg cgatgaagat
    21481 tatcagtggc ttgctgtaaa gcttcttgta aaggcacagc tgcaggaagg atcggaaaaa
    21541 cggccgaaat gccaacatct gctgcttttt cgcttccttt accaacactt ccgcaaatag
    21601 ctatcacagg aacgccctct ggtactcttc tagcaatccc aactggcgct tttcctttta
    21661 gactttgtcc atctagacgt ccttcgccta cgattacgag gtctgcttgc tgtacccgta
    21721 tcgaactcca gtaaatccaa tacgtagtcg atgccagaga ctattttccc tgaagcaaat
    21781 gctaacagtc ctgcacccat tccaccacca gcactactgc ccgatgcctc gattacttga
    21841 ggggcaaatc tcatataaaa atcatgcatg gcttggtcag ccactgctaa ttcattttct
    21901 ttcaagcctt tttgtggtcc gaaaacaaaa gaagcgcctt cttttccgca taaaagatta
    21961 gtaacatcag taatgacagt gattttggct ttaatcagct caataggcac gttcgtttta
    22021 tcaactgtag caattttacc tagattttct cccagtgctt ctactttttg attatcttga
    22081 tcgtaaaaag cataacctag accttctgcc atgccgatgc cgccatcgtt ggtactactt
    22141 ccgccaacgc cgatgatgat gtgtcgaaca ccttgttgca acaattgtcg tatcagttct
    22201 cctactcctc gcgtggataa cctaagtggc tgttgttggt ttagtgggac atctttcaat
    22261 ccgacgattt ctgccatttc aaaaatcgca gtttgaccgt ctgaagcgta ctggatttct
    22321 ttgtttttgc caaatgcatt agtaacgact gctgtttgcc gcttcaacct taaactgtct
    22381 gctaatgatg aaaccgttcc ttctcctcca tcgcctatag gtagcagatc atattcagcc
    22441 tgaacaaaaa cttcttgaaa acctgattga atggcttgtg ctgcctctaa ggctgtcaga
    22501 ctttctttga aagaatctgg cgcaatcaga atacgcatta ttttcccctc cgttccaaga
    22561 tcagttcttt ttccagctgg tattggtctc cattgacaaa aataggtaat gtttctttcg
    22621 tctctttttt tattactatt tgtttttttg tcaaaacaaa tagcaacctg tgatttttcc
    22681 aaataaaagg aaaagaaatt ttttcccatg ctgaaggaag tcttggagaa atagaaagag
    22741 ttccattcgt tactgtaata cctgaaaaac caaatataac tgctagccat agtgctccta
    22801 atgaagcagc atgaattccg tcatctgatg aatgcggatc tggtcctaaa tcaatcaggc
    22861 acgcttcttg gaataaatga tacgcccatt ccatttcttg gatacggcaa gcctctatgg
    22921 cgtgaatcgc tttactcaac gatgagtcgt ggattgtttt gttttcatag taatgcaaat
    22981 tcttagaaac gattggttga gaaaaatact caggtaataa gtataacagc atgacaagat
    23041 ctgcttgctt gctgacttgg agttcattta cttcgctacg ggcataatca agtaaaatag
    23101 actggctgcc aggacgttct ttgtaagtgg tcaaatcaat aactggctta ctgagatacg
    23161 tgtcatcttg cggaatcagc tgttctttgt taggcactgg caaatataac ttatctaaaa
    23221 aattttgaca ttctttcaaa aaaagcggat cgccagcttg atatttaaca gctaaggcca
    23281 cattataatg cgccagatag ttcgtatatg cattattgtc gatatattct gtgtattcat
    23341 ctggaccaat gactctgtgt atctctaaat gatcatcgac ttttacagct ctgctcagcc
    23401 aaaaagctgc tgtttcatga atgagcgttt ttccctttgt ttctaaaaac gattgatcct
    23461 ctgttgcttg gacatactct tgaacggcat aagcaaggtc tgcactgata tgatgttctg
    23521 cggcagctga agcaacttct tgtcttgttc cggttttgat attcaatgca gcaaatttgg
    23581 gtgtctcttc ctgaccagtg tgtgcgcttt cccatgggaa aagtgcacct tgatagtgat
    23641 aatctcttgc tttttgccgt gcgccttcta atcgatcata acggtacagc agcaaattct
    23701 ttgctacttc aggaaactga tataaaaaga aaggcaggat aaaaatttcc gtatcccaga
    23761 aaacatgccc tttataacct tcgccagtta gtcccttcgc ccctacacta acacttggat
    23821 cattgcgggg agtcataatc tgtaaatggt aagcagcgaa gtccatcgct aactgatcga
    23881 aagaagaatc gccttggatc gttatccgat gctgatgcca aaaatctgtc caataagaca
    23941 tcgactgctc taaaatttct gtataactaa cgcttttctg ggcttgggca atacttttct
    24001 taaacgggtc tgtttgctga agagaggtag agagcacgat gatcttctcc agcgtaaagg
    24061 acgtattttt tctgatcttt tctgaaaagg aagcggtgat ccggcgattt tttgcttgga
    24121 atacacctgc tttattgaat ttagctgcaa tcccaatatc aattttactt tctgttgtct
    24181 ggtaggatgc actgatcaaa tcgtcaccaa atactcgcag ttctttttca accaactgct
    24241 gtgtaccaaa attggtttgc tgtccatcga tacccgtttt cacatctact tggcagtctt
    24301 cggtcaacgg cttgatgacc actttcaggg ctgcctgatg gagattattt tgatcagcaa
    24361 cacgacaagt aatgacttcc actttttttc cttgagcagt ttcaatgagc gcatagcgtt
    24421 taagctctcc catttctaaa tctagtgccc gctcgtatgc aagaactttc atcgtctcaa
    24481 gagaaaaatg ttcaccgtcg atttttattt cccatctgat gacatctggg agattcacta
    24541 actcggctga ttctgctcct aaaggtcggt tatatacacc agctgcaaac attcccctta
    24601 cttgattccg atagtcttcc tcctggcttc ctctgatacc aaaaaatcca tttccaatgg
    24661 tcatctgact cgcatactta ttgatatact ctaaatcaaa ctgtttttct tctactttca
    24721 taaggtaata acttctcctg tttctgccga acgatataaa ttttccacca gattctggat
    24781 gacatatcct tgccagccat ctgcaatcat ctgagtctgg tcaccgagcg cccgattcac
    24841 aaaatgagcc atacttagtt catgtgggtc attaactggc gtggtctttt gtaaggaaac
    24901 cagctttcca tctacatctt cgaatagttc gcctggatac agattagcac ctgcctgatc
    24961 gccacaaaaa gccacattca gtttgtcttc tctgatattc aaagcaaacg aagtattcag
    25021 ttggatgatc ttgccgtttt ctaattccag tgtgccaaaa attgcatctt ctactgtgaa
    25081 tttgcttgga tcccatttcc cgaatttccc tgaatttttt ttcgtaccaa ttttttggaa
    25141 gctgtacgcc cgaacgcttt ttactttagg aaatccagta atatacatcg ctgtatcaag
    25201 catgtgaatg ccataatcga tcaaaggccc gcctccttga agttctttgt cgataaacgt
    25261 tccccagcct ggaacaccag accgacgaag cgcattcgct tctacgtaat aaatatcccc
    25321 gagaacatca agatgattct tgatcattgt tgcttcgtca gaaaaacgat gctggaatcc
    25381 ataagccaaa atctgcccgt ttttatcggc tgtctctgcc atctttcttg cttgatcagc
    25441 tgtcatagct ggtggtttct cgcacatcac tgaagcatta gcttcgaggg cagccaatac
    25501 atgttcgaag tgaaagcgat tggctgtaca gacactcacg atatcgggag aaatctcatt
    25561 cagcatttgt gtaactgatg tatacgcatg agaaaatcct gtacgtcggc aaaagtcttc
    25621 tgctcgctgg ctgactggat caaccacagc ggccaattct aagacatctg atcttttttg
    25681 ataataagca gcatgtactt tttctgctac ttgtccagcg cctatgattg ctactttctt
    25741 catttatttc tctctccttt gcttatttac ttattgttat tctttctcta ttctttctct
    25801 aaatcattta aatgacgcgc tgtttccaga cagtttttca agtattgcaa tgattcctga
    25861 taaattttca cttcattttc tcctcgcaaa cgacattcat ataccatata accttcatac
    25921 tcattttgaa gtagcgtttg aaaatggcga gtaaaatcaa ttgcgccaga tcctggttgg
    25981 tagcgatgat tatctgctaa atggatatga cccacatact ctttttgcgt agtcaatgct
    26041 tttgaaatat catcttcttc aatattcata tgataaaaat cagcgatgat ctgcacatgt
    26101 ttcaattgat tagagtcaat gtaatgacgc gcatccgcta acaaattgat catatggtct
    26161 tggtatcggt tcaaaggctc caaataaata accgtacctg tttcttcggc tactttatct
    26221 aaataacgaa gtgattcgct gactgcttta tagtctcctt ctttgcttcg gggtgaaacc
    26281 atcggcggta atcgataagt gaacattccc caagctgctg ggataacgat tcctttgcct
    26341 ccaacctcgc ttagtgcacg caaaatctca gcaatttgac gtacaccatt aagacgccgt
    26401 tcttcgataa agtcaccgat ccacccatcg tagccgttac aagctgtcac tactgggatc
    26461 cctgtttctt tgattgcctg tttgactgtg tcgatatttt ctattaacaa cttaccgtcg
    26521 atttcgtatt cttcaaatcc acagtctttg ataaatctaa atttttctaa aatgtctctt
    26581 gggaaaaatg cttgatcttg cgtaccgaat ttcattgttc tcctcctcgg acttgaacgc
    26641 ccattttgat actttcttct gggtgctggt ctacataacg catgtaagct tctgcgcttt
    26701 ctgcaaatgg cacaactgga tcaatgattt cttcacaatc caagtaaccg ttcatcaata
    26761 attcccaaca tgtgtcctcg attcgtttac ggttccatct tgggtaatct gggtttggtt
    26821 cactagatgc tcgagcaaag acgatttttg cattattgaa atgtgcttcg cgaccaagat
    26881 taaacccagc tggaaaaggt ttagcaaagg caacataaga aatgatcccg ccatagccga
    26941 tccctcttaa agaagcttgt aatgcggcag cactgccact cgtttcaata actgaatcta
    27001 ctccacgttt atctgtcaat tcctttagac gaaaaccgac atctgctttc ataggatcta
    27061 gcgtgtaatc ggcaccgtat ttttctgcta attctctacg ctgcgctatg ggatcgatcc
    27121 caacgatggt agtagcacct gcttttttag ctaattgaat cgcaatttgc ccgatagcgc
    27181 ctaaaccgaa gattgctaca gcatcacctg ctcgaacatg tgcttcccgg ataccaccta
    27241 aagcgaattg agcaggatcg taacatactg catttttcca ttgatccaac cgatcaagtt
    27301 tacgtagttt ataattatca acaccgtttg taatcagcgt ttcacgaatg ggtccataag
    27361 tgcagactaa ctctcctttt tgatactctg tcaccaaact gcccgtttct tcgatcgtac
    27421 cgacaatcat atttcctaat tgaaattcgc caaataccac accgcgttgg cttccttctt
    27481 ctcttggcaa gaataggcgc cattcttctg aaaattcttc atcgataaat ggacttaatc
    27541 ctctaaagtc gacaatttct gttcctggtt ttggagtagc gaaaattact cggatacgta
    27601 cttcgttctt ttcgatctca cggtcttcgt aatctttgaa tccggctatt cttggttcta
    27661 atgcaactaa ttttttcatc ttttctttcc tctttctttt ctttttatcc ttttacgccg
    27721 ccttcgacta aatcaccttt aataaatcgt tcagataacg catacataat gatgactggt
    27781 aaagcggtca ccaatgaagc ggccatcatt cgtccccaaa tgtagtctgg tgtactgaat
    27841 aatgtgttca aaccgattgg taaagtaaat ttttcggagg tcgacaggaa aatcgaagca
    27901 aataaataat cattccacga aaccataaag caataaacga agacagaaat gattccagaa
    27961 atagccaatg gtataatgat ccgaataatg atctggatcc ggctaagacc atcgatcatt
    28021 gctgcttctt caatatcagt cggaatcgtg tcaaaataac tttttagcat gaatatcgca
    28081 gtaggaagtg tttgaacgac catcgtgata atcagtgctg tattggtatc atacaaacct
    28141 agaccggaaa tgattttaaa taatggaaca acgatcaaaa taccggaaaa catataaacg
    28201 gtgtaaaagc tagcattgat tttcgagcga gctttgaagc gtagttttga caaagcgtat
    28261 gccccgctga tcccaatcac tactgcagtt acggaggcta tcaaggagat cactaaacta
    28321 tttttgaaat acatgatgaa tggaaaaatc tcagcattga aaatatcctg ataatgttca
    28381 aaagtccatt ctttcggaaa aatagtttgt gtcgttgcaa ttgcttcttg tgaatccttg
    28441 aatgatgtca tcagcatgat caaaaatgga aacaaattga cagctaatag caacaaaatc
    28501 gtcgcgtaaa ataagatttt cctgctcttt ttatttttca tttcaagtcc accttctttc
    28561 gtgagagcaa gacgaccgct gcaataatga tgaacaatag aatcgatata gctgctgctt
    28621 ttccaagatc attgaacgca aaggctgtct gatacaaata aacgcctaag atattgactt
    28681 tattcgtcag tagatagaca tctgtaaaca tatagaacat ccagatagat cgtaaaacaa
    28741 tcacagttgc tagtactggt ttgattgccg gcagtgtcac gatcttgaac ttctgccaag
    28801 catttgcacc gtccatttca gctgcttcat aaagcgtttt gtcgactgtt tgcaaaatag
    28861 ccaaaaatga aataaacgca tacggatagt atctccagat agcaaacaaa acgaccataa
    28921 agaagctagc aactggctgg tcgaaccaca gcggtgcttc gttgaaaagc tgcaacctat
    28981 ctactaacag atcattgacg attccataac tattattgaa catatatttc caagcaaaaa
    29041 tcaaagaaat agatggcgta acataactta ataaaatcag tgaacgcacc gttttcctaa
    29101 atctgaactt gcggttaagc aaaatagcta cggctaatcc taaagctgta ctgcctgcta
    29161 caactaagaa tgtgtaagca actgttaaac ctaaagaacg ataaaattca ctatcactta
    29221 aaatttcaag ataattgctt aatccgataa aaacggcgtc tgagttagga ttcagcggca
    29281 tatcgaaaaa actgatctga atattggaaa gcattggaat cagcactaaa acagctaata
    29341 aaagcatgct tggtgctaaa agtcccatgg ctaattttaa gtcagaatgt ttccttggac
    29401 gattcattga aacctccccc tgataatctg ccaatagcta tctacttttt tcgaacacca
    29461 ttggcagaac ttcttgttat ttcgtatttt tttgtgcgtc agctaaagct tgatcgacat
    29521 cttcgtttcc gacagttact tggttcactg cttttccgat cacacctgag cttgtgatat
    29581 ctcccatttt cgtgaaattc ttttccccga ctagtccaaa gacttgtact tcatcaaaag
    29641 cactagcaat ctcagatggc agctcgccaa aagacttgat gacttcattt tctttgtaac
    29701 catccagttc gactacttgt ttattcactg gttgagcacc accaggagac atcaagaccc
    29761 acttttccat gtttttcggt tgagataaga aagctgtgaa tgcttcagca gcctcttttt
    29821 gtttctcgtc tagaccagaa gaaatcgtca atccagatac tgtgccatag acagcttgat
    29881 ctttttgtgt tgggatagca aaaccgatat tttctgagtt ccccgcttca taaacagaag
    29941 gcaaaatgta agttgaatag attgccattg gtgctgttcc attcatgaaa gcatctttga
    30001 tttctgtcac atcattagag cctggcatcg tgtattggga taagttttga taaaacgaca
    30061 atgcttctct catcttttcc gtatcgatcg ttacctcgcc ttcatcatcc aaaacatttg
    30121 ctccatttga caaagcaaat tgagagaacg cttgctcact cattgttcct tcagcagtag
    30181 gcatagcaat tccatattgt ttattctctt tatctgtgaa atgttgagca atttttaaaa
    30241 tatcatccca attttctggt tctgaaaaac cagcttctga taatttttct ttgtcatacc
    30301 aaataccttg aacccagccg ctaattggtg cagcaatata gctttttcca tcttctgaac
    30361 gaacaaggtt tttggctccg tcataataat tatcttctcc agcttcctcg ataacgtttt
    30421 ggactgccgt ctgatcaatc agttcatctt tatccatcac tttagcaaaa tcctgactga
    30481 cttccattac ttctggtaat ttaccggaac gagctaacgt aacgattttt gtattgaacg
    30541 ctgattcttc taccggcact tgcttgattt tgatgtctgg attttctttt tcaaaatcag
    30601 caaccagttc attgatcaca cttaatcgtt cctgttcgac agaagagtgc atgaattgaa
    30661 tcgttgtctg ttgtgattcg ttagagcttt gactttcacc acaagcagta agaagaaatc
    30721 cagtagctag cagacaggta gtaacaataa tttttttcat ttttttccac ctcttatttt
    30781 attattttca gccacatata ttcatacggc tggaatatca actttcgttc ttgactgcaa
    30841 tggataattt gtccagaaaa caggtctagg taatctcctt ttggtaaaag ataacctgct
    30901 gattgattgg aaaaattatg gataactaag actttctctt ccttcgcttc gcgaataaaa
    30961 ctgataaaag aatctgctga gtccagtaag taaatcaaac tattcggatg gaaggctttt
    31021 tctttttttc gaatagatag catctgggtc aattcaccat atactgctgt tcttaatgga
    31081 tctgtctgca actctttctc aatatctgct aacaaaaatt tttgccgatt gatttttcga
    31141 ttctctcctg ttttttctac gcctttgtaa tcatttcgac ttcccagcac actttgaata
    31201 taaattgccg gcacgcctgg taacgttacc aaaaatgaat gagcagctaa aaagcgtttg
    31261 cttctccatt ccgtcgtatc tgttggagaa cttaacgcat ctagatacgt agcgtttatc
    31321 tcatatggac tggtcgttcc atctgggttt ttcttgtagt ttactcgggc accctctttc
    31381 ttcagctgtt ccactaattc aaggatcgtt ttttccggca gaatacctcg taccggattc
    31441 aatccgatac cgtcatggga ggctaaaaaa ttaaaaaaag ttgttttttt cgatgcgaaa
    31501 tcgatggttt ttaaccattc tttcaactta cttgtattac ccgaacgaat cgcttgaagg
    31561 gtcaaaggtg gtagcgaaaa ctgatagacc atctgtgctt cattctcgcc attcccaaaa
    31621 taactgatat tatctttgtg tggcacattt gtctcagtga tcaataccgt tcctggagct
    31681 gcttcatcag cgattgcacg gaataattgg atgattttat gcgtttctgg caggtgtata
    31741 caagaagttc ctagttcttt ccataaaaat cccacagcgt ccaagcgaat aaatgaagcg
    31801 cctttttcta agtaaaacaa aagaatatcg atcattttca ataaaacttc tggattttta
    31861 aaattcaagt ctacttgatc ttcgctaaaa gtcgtccata cgtgtttttc tttcccgttt
    31921 ttgtcaatga acgttgtaag taacgggctg gtccttggtc tagtcacgct gcttgtatct
    31981 gtatccagtg gcaaatcaat aaaaaaatct ttgtacgtat cattcaagtt taaatattcc
    32041 tgaaaccaag tactttcggc agacatatga ttgcagacaa agtcgaacat taaccgtgtt
    32101 tcgcttctca tttcttctat atcttcccat gtgcccaaac ggtcgttgat tgcctgataa
    32161 tttacaacgg agaaaccatc atcagatgta tatgggaaaa atggcaagaa atgtacaact
    32221 ctaaatgtat ctgccaaata cttttgataa aatttcttaa atgtacgcaa agttggttgc
    32281 tgctcttcaa aaaattgatc cccataagta atcaagaaaa tatcttcttc gtcccaatgc
    32341 agtttgcctg cctggccttt cttctgctga taaacactga ctttttgttc aatcatagag
    32401 gcggttttct cagacaaatc tgagtcgcga taaatcgctt gtaaaagttt tgtatacatc
    32461 ggattcccct ttcttttttg ggagcgttcc caacgatttg atcatattat ggaaaacgct
    32521 tactgtcaat agcatttttt taaataattt tgatatacac aaaaatacaa ataagaaagc
    32581 ttatgtatca ataattaata gcttcttaaa aaaatatggt ctctcatgat catgcaagct
    32641 attcctaaat tttcaaaatc atagacaaaa aagaatgtct attgtactat ggaattattc
    32701 taaaacgctc ccaaaaagga ggtgcatata aaattgaaac ctactattta tgacattgcg
    32761 aaaaaagcta atgtctcaaa atcaactgtc tccagagtat taaataacca gccaaatatc
    32821 tctgataaag caaaagcaag tgtacttcaa gcaatcaaag aattgaatta tgaaccgagc
    32881 aaaattgcaa gaggactgtc aggaaatggt tttgacgcga ttctagcatt atctcatcgt
    32941 acttctcata cgacctatgg caatcctttt ttttcagatg ttattcaatc catttctgcc
    33001 gtttctgaac aaaataactt cgacttgatt ctacaaacgg caaaaacacc agaagaagag
    33061 ctagaaaaat gcgcgaaaaa gatccaagaa aaaatgatcc gaggaattat tattttaagc
    33121 tctacgatgg atgaaacact tctttttgaa ttggatcaat acaatattcc tattgtggta
    33181 atcggaaaag tcggaaacga ctacacgaac atctactcag tggacacgga taatttccag
    33241 gatagttacg atttggtgga aacactgatc aagaatggac accgtcatat cggctgtctc
    33301 catgctccga cagaagttta tgtatccaat gatcgtctca atggttaccg tcaatgctta
    33361 tttgatcacc acctagatat ccgtaatgaa tggattatag acggcggctt tcgcttagaa
    33421 gatagcatgg cagcaatgaa tgatttaatg aagctacgag aaagaccaac tgcgattttt
    33481 tctaccgatg cattaaaatc attgagtatt tacaaagtgg cagaacaatc tggaaagcag
    33541 atacctgatg atctttcgat cgcaggattc agtgatccct tattgtcctc cctattttcg
    33601 ccacagttga ctcggataga cattccgaca aatcagttag gaatcaaagc cacagaactt
    33661 ttattccaac taatccacca ccaataccct gaagaaaaaa gaatcattct ttcaaccgag
    33721 attactctca cagattcgat ccaacaacaa gaaatgtaga acagaattat aaaagaacag
    33781 aaacactgag gataagtcag ttactctgtt cttttttcaa tcactcatcc ctcgttaccc
    33841 cctcccggta ttttagcgaa tttttcttat tttccatctg ttttagatag ctgtggataa
    33901 ctataatgtt tgtgttaaac tattttttcc acagggaaga aaaaactatt tttaaccacg
    33961 ttgtgtataa gtttttatag ttcgtttttt taaacacatt tacccttatt tcaatccatg
    34021 ttatttgggg atacttatct ctaaaacata aatagaataa cagacatgtc tactggtttt
    34081 gttttattcg aggaattatt caataatagc tagcaaaata ttaaaaataa ccgctctatc
    34141 ttcccatcaa tttattttgc attcaaaaaa tgatctatct ttacttttgt tgattgactt
    34201 ctcttggaag atgatcgttc cgatacctta attggatacg aaccgatgtt gttaagatcc
    34261 tttcccactt ttcttctagt tagacaaatt attttagaca aaccaaaaaa gaggttgtga
    34321 caataatttg tcacaacctc ttttttaaaa tatctatttt gtttgattgt tcattgcgtc
    34381 ttctgcagcc atttgcgctt caatatctga aatactgtag acattttcgc ttgctacacc
    34441 gacttctttt ggttccatgt cacgataacg ttgcatacca gtaccagctg ggatgatctt
    34501 acctataata acattttctt tcaaaccaag aagaggatct ttcttaccgc ggatcgcagc
    34561 atccgtcaag acacgagttg tttcttggaa tgatgcagca gataagaaac tatttgtttc
    34621 taatgatgct tttgtgatac ctagtaagac aggtcgagaa gttgcaggaa cgcctcctga
    34681 gactagcgta ttgtagtttt gatctttaaa gtctgcgatg tctaataatg tacctggtaa
    34741 gatatctgta tcacctggat ccattacacg aactttacgc agcatttgac gaaccattac
    34801 ttcgatatgc ttgtcgccga tttctacccc ttgcatacgg taaacacgtt gtacttcacg
    34861 aagcaagtag ttttcaacag ataatacatc gcgaacttgc aacaattgtt ttggatcgat
    34921 tgatccttct gtcaatggtg caccacggtg gatcatatcg ccttctgcta ctttcatacg
    34981 tgctgtataa ggaacagtat acgtacgtgt atctgttttt cctttgattg ttacttcttt
    35041 ggtacgtgtt gcaggatctt ctgagatatc gatgacatcc cctgttactt ctgtgatcac
    35101 tgcttgccct ttcggattac gtgcttcaaa gatttcttgg acacgaggaa gaccttgagt
    35161 gatatcgtct ccggcaaccc cacctgtatg gaatgtacgc atcgtcaact gagtaccagg
    35221 ttcaccgatt gattgagcgg cgatcgtacc aactgcttct ccgacttcaa cgtcagagcc
    35281 agttgcaagg ttgcgtccgt aacaatgttt gcagacacca tgttttgtat tacatgtgaa
    35341 gacagaacgg attgtcactg tttcgacacc tgcatcaacg atttgttttg cgatgtcttc
    35401 ggaaatcaat tggtttcctg caatgatcaa ttcatttgtt tcaggatgac gtacttcttt
    35461 acgggtgtaa cgtcccacta aacgatcttc taatgattcg atgatttcat ttccctcgcg
    35521 gatggcttgg atttcaagac ctcggtcagt accgcaatct tcttcacgga tgattacatc
    35581 ttgggccacg tcaaccagac gacgagtcaa gtaacctgaa tcggcagtct tcaaggctgt
    35641 atcggtcatc cctttacgag ccccgtgagt tgagataaac atttccaaga cggatagtcc
    35701 ttcacggaag ttcgaaatga ttggcaattc catgattcga ccattaggag cggccatcaa
    35761 accacgcatt ccggcaagct gtgtaaagtt ggaaatgtta ccacgagctc cagaatcaga
    35821 catcatgaag attggatttt tcgcttccaa accttccatc agtttttgtt ggatgctgtc
    35881 ttttgcagca ttccaaacag caatgacacg ttcataacgt tcgtcatctg tgatcagacc
    35941 acgacggaat tgttttgtaa tagtttcaac ttgtttatgg gcattttcaa tgatttcttg
    36001 tttttcattc agtacactga tgtcagcgat ccctactgtg ataccggcat gtgtcgaatg
    36061 tttgtaccct aagtctttca tacggtcaag catcttagaa gtttctttta ctttgaatcg
    36121 tttgaagact tctgcgatga tgtttcctaa gtttttcttc ttgaacggta atactaattc
    36181 ttgctctttg atatgtgcag gaatatcagt accagcttca acaaagtatt tgtccggtgt
    36241 ttggacggtc aagttgaagt ctgttggttc attcagataa gggaattcag gaggcatgat
    36301 ctcgttgaag atgatcttac caactgttgt gatcatcgta cgttcttttt gccattcagt
    36361 aaatggtttt tcacctaatg agttagggtt cacaccgata cgtgaatgta aatgaacata
    36421 tccgttgcgc catgcgataa cggcttcgtt ttgatctctg aagaccattc cttcgccttc
    36481 gcgtccttct tcttccattg tcaagtagta gttacctaga accatatctt gagaaggagt
    36541 aacaactggt ttaccatctt tagggttcaa gatgttttga gcagctaaca tcaacatacg
    36601 tgcttctgct tgtgcttctt cattcaatgg aacgtggaca gccatttggt ctccatcgaa
    36661 atcggcatta taagcttcac atacaagtgg atgcaaacgg attgcgcgtc cttgtactaa
    36721 aactggttcg aatgcttgga taccaagtcg gtgaagcgta ggtgcccggt tcagcaatac
    36781 tgggtgttcc ttgattacgt cttctaaaac atcccatact tcgtcttctt gacgttcgat
    36841 tttacgtttc gcatttttga tgtttgaagc tagttcgcgt tgaacaagct cacgcatcac
    36901 gaatggtttg aataattcaa tggccatttc ttttggaagt ccacattggt acatcttcaa
    36961 gaaaggtcca acaacgataa cggaacgacc tgagtagtcg acacgtttac ctagcaagtt
    37021 ttgacggaaa cgaccttgtt tccctttcaa catatgagaa agagatttca atgggcggtt
    37081 acctggtcca gtaactggac gtccgcgacg accgttatcg atcaatgcat ctactgcttc
    37141 ttgcagcata cgtttttcat tttgaacgat gattccaggt gcattcaagt ctaacaaacg
    37201 tttcaaacgg ttattacggt tgattacacg acggtaaaga tcattcaagt cacttgttgc
    37261 aaaacgtcca ccttctaatt gaaccattgg gcgtaaatct ggtggaataa cagggataac
    37321 gtccataacc atccagcttg gttgatttcc tgaagcgcgg aatgcttcta aaatatccaa
    37381 acggcggatt gcacgtgtac gtttttgtcc ttgtgcagat ttcaattctt ctttcaattc
    37441 ggctgcttct gcatctagat caacattatc aagtaattgt ttaatcgctt ctgcacccat
    37501 agcagcttgg aattcttgtc catattgttc acgtttttcg cgatattcgc gttctgtcaa
    37561 caattgtttt ttctctaaat tcgtatttcc tggttcgatg actacatatg aagcaaaata
    37621 aatgatttct tccaaagcgc gtgggctcat gtctaataca agacccatac gtgaaggaat
    37681 ccctttaaag taccagatat gtgaaacagg agctgctaat tcaatatgtc ccatgcgttc
    37741 acggcgaact ttcgaacgag taacttccac tccgcatcga tcacaaacga ttcctttata
    37801 acggatacgt ttgtattttc cgcaggcaca ttcccagtct tttgtaggac caaaaatccg
    37861 ctcacagaac aacccttcgc gttcaggttt taaggtacga tagttaatcg tctcaggttt
    37921 ttttacttca ccgtaagacc agcttctgat tttttcggga gaagccaaac ctatttgcat
    37981 actttcgaat ttatttacat cgatcaaaag gggttccctc catttcattt aatggcaaac
    38041 cgcaagacgg ctgatcttcg accgccttgc agctcataga ccggattagt ctaaattatc
    38101 ttctgcggtt tcaaagtttt ggatgacatc gtctttttca tcttccactt gttcagcagc
    38161 tttcttttct aattctttgg cagtttgctg ttcggcaaat tttgtcaaag catcaacagt
    38221 gatcaaatcg tcgtcttcat cgtccatgtc gcgaagttcg atctctgttt cttcgatatc
    38281 caagacacgc atgtccagac ctagtgattg caattctttc accaatacgc ggaatgattc
    38341 cggtacacct ggttttggaa ttggttcacc cttgacgatt gcttcgtatg ttttcacacg
    38401 tccgactacg tcatctgatt tgtatgtcaa gatttcttgt aaagtataag ccgcaccgta
    38461 agcttccagt gcccatactt ccatttcacc aaaacgttgt ccaccaaatt gagctttacc
    38521 tcccaatggt tgttgtgtaa ccaatgagta aggtccgatt gaacgtgcat gcaatttgtc
    38581 atcgaccatg tgagcaagtt tgatcatgta catcacaccg acagacacac gtccatcaaa
    38641 tggttcacct gtacgtccgt cgtacagaac agttttcgca tcgctggcca taccggcttc
    38701 acgaactgtt tcccatacgt cttcatcact tgcaccatca aatactggcg ttgctacgtg
    38761 gatacctaac tgacgtgcag ccatacccaa gtgtaattcc aatacttgcc cgatgttcat
    38821 acgtgaaggc acccctaaag gattcagcat gatatcgatt ggtgttccat caggtaggaa
    38881 tggcatatct tcttccggca taatacggga tacaacccct ttatttccgt gacgaccggc
    38941 cattttatcc ccttcatgga ttttacgttt ttgaacgata taaacacgaa ctaacatgtt
    39001 tacgcctggt gacaattcat ctccagcttc acgagtaaag attttcacat cgtgaacgat
    39061 accgccgccg ccatgtggta cacgtaatga tgtatcgcgg acttcacgag ctttttcgcc
    39121 aaagatcgca tgcaatagac gttcttctgc agataattct gttacccctt ttggcgtgac
    39181 tttccctaca agcaaatcgc catcttggac ttctgcacca atacggatga tacccatttc
    39241 gtctaaatct tttaatgcgt cttccccgac attagggatt tcgcgtgtga tttcttcagg
    39301 tcctaatttt gtatcgcggg cttctgattc atattcttca atatggatag aagtgtatac
    39361 gtcatctttt accaaacgac ggctcatgat gatcgcatct tcatagttgt acccttccca
    39421 agtcatgaaa ccaactaaaa cgttttggcc tagagccatt tcgccttgtt ccatagatgg
    39481 tccgtctgcc agagtatccc ctttttcgac tttctcaccc aaatgaacga ttggacgttg
    39541 gttgtagctt gttccggagt ttgaacgacg gaattttgtt acatcgtatt tatctaatgc
    39601 accgttgtcg cggcgtacgc ggatttcaga agcatcaacg tattcaacga caccatcatg
    39661 tttacataac aaagcagctc ctgagtcatg cgctgatttg tattccatac cagtaccaac
    39721 ccatggtgct tgaggattga tcaacggcac tgcttgacgc tgcatgttgg cacccatcaa
    39781 ggcacggttg gagtcatcgt tttccaagaa aggaatacat gctgtcgcaa cggcaactac
    39841 ttgtttaggt gatacgtcca tgtagtctac tttatcaata gatacttcta agttttcact
    39901 ttgagcacga gccataacaa cgtcttgagc aaatgttcca tcttcattca atgggctgtt
    39961 tgcttgggct acgatgtaat ggtcttcgat atcagctgtc aagtagtcga tttggtcagt
    40021 aacacgacct gtttcacggt ctacacgacg ataaggtgtt tcgataaatc cgaatttatt
    40081 tactttcgca taactggaca aactattgat caacccgatg tttgggcctt caggagtttc
    40141 gatcggacac atacggccat agtgggagta gtgaacgtca cgaacttcat aaccggcgcg
    40201 gtcacgagtc aatccgccag gtcctaaggc gaaaagacga cgtttgtgtg tcaattcgcc
    40261 aagagggttt gtttgatcca tgaactgtga caactgagaa gaaccaaaga attctttgat
    40321 acttgccaca actggacgga tattgatcaa ttgttgaggt gtcaatgttt cagtatcttg
    40381 gatcgacatt ctttcacgaa ccacacgttc catacgtgct agcccgatac ggaattggtt
    40441 ttgtaaaagt tcaccgactg aacggatacg acgatttcct aagtggtcga tatcatcgac
    40501 attgccgata ccttccatca agttcaagaa atagctcatt gaagcaatga tgtcggctgg
    40561 acgaaccgtt tttacagctg cttctggata gccgtttccg atcacgttta cttcacgttc
    40621 agggtctctt ggtgaaaata ctttgatgac ttggacagtc attggatctg tgaccacacc
    40681 gtcttctgat ggatagtaag tcactgaatt taggccatta tcaatgaaag gagctagtgt
    40741 ttccatgact tggtgagtca gaactgttcc tttttcaacg atgatctcgc ctgtttctgg
    40801 atcaactaat gtttcagcta atgtcagatt caatagacgt gttttcaaat ctaatttttt
    40861 gtttactttg taacgaccaa cgtttgctaa gtcgtaacgt tttggatcga agaaacgagc
    40921 attcagcaag ttacgtgagc tgtctgctgt ttttggttcg cctggacgca aacgttcgta
    40981 aacgtctttc aaaccttctt ctgttcttga gtcgcttgcg tttttatgca agtctttttc
    41041 gactgtattg cgtaatgttt cgctgtcgcc gaagatttca aagatcgtat catcggaacc
    41101 aaatcctaac gcacgaacta atacggttaa aggaatctta cgtgtacggt cgatacgtac
    41161 ataagagatg tcttttgcat cagtttccat ttctagccaa gctccacggt tagggataac
    41221 agtagaaccg aatccttctt ttccgttttt gtcgactttt ccatggaaat agacacctgg
    41281 tgaacggact aactgagaaa cgattactcg ctctgccccg ttgatgatga atgttccttg
    41341 ttctgtcatt aatgggaaat caccgaagaa tacttcttgt gctttgattt cgccagtctc
    41401 gcggtttgtc aaacgcaatg ttacatgtaa tggtgcagag tagtttgcat catgcgcacg
    41461 agcttctgct actgtatact ttggttcttt caattcataa tctacaaatt ccaaagatag
    41521 attgccattg aagtcatcga ttggcaaaat gtcttcaaac atttctctaa gtccctcatc
    41581 taagaaccat tggtaagagt ctgtttgaat ttcgatcaaa tttggtaatt ccaacacttc
    41641 actgattctt gcgaaacttc tacgttcgcg atgttttccg tattttacta cgtgtccagc
    41701 caagctcttc acccctctaa aatgtcattc aaaaagacta cccgatcaat tgttacaata
    41761 atatttcaaa tattattttt aggtaacaac agacattttt tgcggctttt aggcaaaaaa
    41821 aaaccaaaaa tagaacattc tcttgaaacc ttacttcgtg agcttctact tttgtttcct
    41881 tatattaaag ccgaaacgga caatatttcg tttctgcctt ttcttcatca gatagttttt
    41941 gcaacttcat atactacact tattttctat aaaagtcaac acttcctggc gtttcttctg
    42001 ctttttcgca acattttctt aatgttttca attttatgtt ttcaattatc tgacaattct
    42061 taattgacag acctttttat ctcggttata ctttagaaaa ttcattttgt ggaggaactt
    42121 ctatgcgaac caacatcaac caaatcgcac caacacaact gaataacttt tactttagct
    42181 actttagata ggtttgtatt catcatgatg gatacaaacg ttaaacgaca gtttgtatct
    42241 atgatggcta aagaactttg tattgcagca aaaagccacg tagacaaaat gctaagtggc
    42301 tgagcagtga aaatacaaag taaaagtatc aagcattcta ctttttcaat ttattttccg
    42361 acttttcaat ccatttggac attttgtctg aatggatttt ttgtttccca aaattaagga
    42421 ggaaaaagaa atgaaaaaaa atataatcat cggattaggc gctgccctgc tactagcttt
    42481 aggaggttgc gcacaaaaag acaattccgc agaggcatca gatggacaaa aaacaattgg
    42541 cgtattgcaa cttgtacaac ataactcgtt agatgctgcc tataaaggat tcaaagaagg
    42601 attagcagaa gaagggtata aagaaggcga taatctaaca atcgattatc aaaatgccca
    42661 aaacaatcaa gacaacctga aaagtatgag tgagaaactc gtcaaagaag atcctgattt
    42721 gctacttgga atcgccactc cagcagcaca atctttatta aatgaaacaa ccactatccc
    42781 gatgactgtc acagcggtca cagacttgga acaagcccat ttagtcacat ccaatgaaaa
    42841 acctggcggc aatgtgactg gcacgacaga tatggtgcca atcgaaaaac aaatcggctt
    42901 actgttaaat atcgtgccag acgccaaaac aatcggcatc atgtataaca acggtgaagc
    42961 aaactctaag atccaagctg atttggcaga aaaagaattg aaaaaagcgg gcgtcaaagt
    43021 caaagtactg acagcaaatt ccacaaatga tgtccaacaa gtgacgaaaa gtctagctaa
    43081 agatgtagat ggaatctata ttcctactga taacacgttc gcaagtgcgg caagtgttgt
    43141 cggtgaagtc gcaaaagaaa caaaaacacc tgtcgttgct ggcgcagttg atcaagtcaa
    43201 agacggcggt ctagcaacag taggaatcga ctacgaaagc ttgggcaaac aaacagggat
    43261 catggcagca aaaatcttag acggcaagaa tccaagtgaa cttcctgtcg aaacagcgaa
    43321 tgatttggaa ctgtatgtca ataaagacat ggccaaagca ttaggcatca atccagacag
    43381 catcaaagaa gctgaataaa acacaggagg attctcatga caaatttgct ctctcttttc
    43441 ttatcatctg catcgcaagg ggtcttatgg gccctacttg cgattggtgt atacgtcact
    43501 ttccgtatct tggacattgc cgacttgact gctgaaggaa gctttccttt aggtgcaggg
    43561 atcgcggcag taagtattac aaatggctat catccattga cagcttgtct tctaggcttt
    43621 ttagggagtg cggcagcagg gcttgtttcc ggactgcttc acacaaaatt gaaaattccc
    43681 gcccttcttg cagggatcat caccatgact ggtttatatt ctgtcacatc ccgtgtgatg
    43741 ggtgcgccga acatctcttt attgggtcag ccaacgatct ttcattgggt cgagtcattc
    43801 ggcataacaa aagacaacgc tgtactgatc gtcggtctgc tttttgcttt gatcgttgta
    43861 tgtttacttg ttttgttctt acgtacagaa acaggacttg ctattcgtgc aactggcgat
    43921 aatctggcaa tgagcgaagc aaacgggatc aacacagata atatgaagat catcggttat
    43981 atgatttcta atggatgcat tgctctttct ggctccttgc ttgcgcaaaa caacggcttt
    44041 gctgatttaa attctggtat tggaacgatc gtaattggac ttgcttctat tatcatcgca
    44101 gaagttttgt tacgtaacca gccactattt ctccgtctct tgactgtcgt tttaggtgcg
    44161 gtcatttatc gttttatttt agcgttagtc ttcgaactga atgttgaacc aagtgattcg
    44221 aaacttgctt ctgctttcgt gctagtgatc tgtctttctt tcccgcagat ccagcaaaaa
    44281 ttccatttac ctcaaaaaaa gaaaggcggt agtgtcaaat gaatgacgtc ttaacattgg
    44341 aaaatctcca tcataccttt gaaaaaggaa cgatcaacga aaatcatgtc ctgaaaggca
    44401 ttaatctttc cttagatccc ggcgacttcg tgacgatcat cggtggaaat ggggctggta
    44461 aatctacttt gctgaacagc atcgccggta cattttctgt cgatcagggt caaattttat
    44521 tgaatggaaa aaatatcacg aaaaaatctg ttgtcgaacg ttcgaaatcc atcagtcgcg
    44581 tattccaaga tcctaaacta gggacagccg ttcgtttaac ggtagaagaa aatcttgctc
    44641 ttgctatgaa acgaggaaaa aaacgcggct tcttccgtgg tgtcaaacca caagaccgaa
    44701 catttttcaa agaccagctg gttcggctaa atttggggtt ggaaaatcgt ttatcctcag
    44761 aaatcggttt gctgtctgga ggacaacgtc aagctattac gttattgatg gccacattac
    44821 agcgtccaga actgatctta ttagatgaac acactgcagc gcttgaccct gctacttcca
    44881 aaacggtgat ggaattgaca gaaaagctga tcactgagca gaatctcact gcttttatgg
    44941 tcactcatga catggaagac gcgatccgct atgggagtcg actgatcatg ctgcatcaag
    45001 gaaggatcgt cgtagatatc cagcaagagg aaaaacagca gctcacagtg ccccaattat
    45061 tagcgttgtt caaacaaaac agcggcacgg cattaaaaga cgatcaagta cttttatctt
    45121 cataatcaga aagaggatgg gacaaaaaat gaacgcccac cctcttcttt tttctctttc
    45181 cttctttcgt ttttgcttta tgtatcaacc gttgtttctt cgaaaactat tttgttctct
    45241 ccttcttcct gatagaatgg atgggaaagg agcttgatgc catgacaacg aaagacaagg
    45301 tacttcaatt attgaaaaag acaccagatt ttctttccgg agaaaagttg gcacagcaac
    45361 tggaagtttc ccggacaagt atttggaaag ccatcaaaga attggaaaag gcaggctatc
    45421 gttttgagca cgggcctaca gggtatcgtt acctgccctc tgacgtacta gatgcaaaag
    45481 aaatccagca agagctacgg tcgtttattc ctgatttgaa agtacaaacg atgatgactt
    45541 ctgaatctac gatgaaagat gccaaactgg cagcagctca aggagattct gtttcgaagt
    45601 tatttgttgc tgatacacaa gaacaagctc gtggacgttt tggacggcct tttttcgctg
    45661 aacctggacg aggaatctac atgagtctct tgctccatcc agacaaacgg tttgatgaat
    45721 tgcctcaata tacgatcatc gcagccagtg cctgtgtgaa agccattgaa tctgtaaccg
    45781 gtcgttctgc ttcgatcaaa tgggtcaatg atatctacat ggatggaaaa aaagtctgtg
    45841 ggattttatc tgaagcagtc agtgatatgg aaagcggcag gatcagtcat atcatcattg
    45901 ggatcgggct taatttttct gttcctcaaa atcattttcc agctgatctc caagaaaaag
    45961 ccatctctgt ctttcccgac ggacaagcta gtgtcacaag gaatcagcta atcagcaaaa
    46021 tctggcaaga attgttcact tatctttctc acccagaaaa agcgttggac ttctataaag
    46081 aaaaatcatt cgtattggga aaaaccgtgt cgttcaatca aaaaggaacg acttatgtcg
    46141 gtcttgcaaa agaaatcggt gatcatggcg aactgatcgt ccaaacaaat gaacagaaga
    46201 tgagtttgtc ttctggcgaa atcagtctca catctatccg tacgcaataa ttatcagatt
    46261 tcacaaaagg acacctgatc tcatacagtg tccttttttc tgaattctct tcaaaagact
    46321 ctccttattc tatcagctga cagtttctct atcctctaga aaaaggtatt ctaaaaatat
    46381 ctataaagca tggtacactt tctttaaatg aatcaatgca aaaaacaaga gagtcatcag
    46441 tttacacgat caaaagagat agcaggccgc ttcctttttc aatcttatag atagaccatg
    46501 ggtaacgata aaaacaaaaa agaacttgcg acttattttg ccgtaagttc ttttttagct
    46561 agtgccttaa tctcttaatc ccaacaaacg tctcgcatag atcacctgac cagagtgcat
    46621 agcagcatca tcaataatag aaacgagacg cattcctcgt gtgactggtg gtgtccagtt
    46681 ctcgtcaatt acttcatcta gctcggaagg ttccagcctt cttaagtaag aaatagcaaa
    46741 atcagcagct cctcgcaagt atcctagcag atcttctatt tgattagctt ggatctgctt
    46801 tgcttgttcc agactatgct tccaatcttg ttcgttatct gctatcgtca tcggaaaccg
    46861 gctttcccag tcttgactat gccaaattgg agaagttcct gctaaatcag caatctggaa
    46921 atctaattct cgagcggtat gccaagccag ccaagtcatt gatttgatct gcggggctct
    46981 atcttccact ggaaaacgat tggcctcctc aatagagacg ccttcaaaca aacgttcaaa
    47041 ccgatcgtat gcccgatcca cactctcgca tagcatatct aaataatcca tttattttcc
    47101 tcctttttat ttatcctact tactttttcc taattctagg atacctactt atatgttact
    47161 acacaccctt attttttaca ctttaacagt caccatcatc aatagtttgg agattgaaag
    47221 aaaaagatag tgtcgaacta tcaattgaac aagaagcaac aatatgaacg tttcattaat
    47281 attctttaaa taaacaatga tttttcaaac gaacagttta agactaggag aaaaagagta
    47341 taataggaaa atgtttgaaa ggaaaggaag gggaaaaatg aaaaaaaggg caagtttact
    47401 agtcctagtt gctttgttgt tcaatatctt ttcgtatggt gtggccgttt cagcggaaac
    47461 atacattcct aaagaccctg ggaatattta taatgatcta actggtaact atggcttgtt
    47521 aggaattgct agtcaattcc acgtatttgc taaaaataag acaactgtga atgcacatac
    47581 agacggaaat atagcaacac atgaacttga tgcaaaaaat aattttggta cagagcttca
    47641 tgaaggttta ttgaaccaag aaataaatta tatacaaaaa actgattctt tcgctaattc
    47701 ttcaggcata cctacaggta gcacaagaat gaataaattt gtcgttggca gtaacgtgga
    47761 tgtagcactt caagatggtc atcctacagt caatggatcc aggcttgatc acttaactcc
    47821 agatgatttt tataaagatc gtgctgggca tgaatatatt gatttcgagc aggaatttgc
    47881 taaattgaat gtagcagcaa atgatcttgc aacgatcact ccagctaaaa catatactgc
    47941 tgcagatttt ccagacatga acaatcggac aatcgattta actgatttat cagataccgg
    48001 gtttttattg gtaaatatcg atgcagaagt gttaacgatg aatacgccac ttcaaatcat
    48061 taatccaaat gatcaagtag ttgtatttaa tgtcatcaac agttcttctg cattgaacgt
    48121 acagtcacca atcaaataca atgatcgttc aaatcatgaa acagaagatt tttcggatgc
    48181 gaatatctct tggaattttg gaaatgagat gactgatttg acaatcagtg ctccttttca
    48241 aggaacaatc cttgcgccta atgctactat ccgcattact caaaaccaag acggaacgat
    48301 tataggaaca aatgtgattt tagatgcagc taccaatcgt tgggatccta acgaaatatt
    48361 tatcagcgac aatggtacag atacgacaga cacaagcgac agtacagata catctaccac
    48421 aagtgatagc tcagattcat ca
//
LOCUS       DACCVZ010000013        44847 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.013, whole genome shotgun sequence.
ACCESSION   DACCVZ010000013 DACCVZ010000000
VERSION     DACCVZ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.013"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            212..604
                     /locus_tag="IVW63_000710"
     CDS             212..604
                     /locus_tag="IVW63_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP7859008.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="IVW63_000711"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="IVW63_000711"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HAP7859009.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="IVW63_000712"
     CDS             3165..4775
                     /locus_tag="IVW63_000712"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HAP7859010.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="IVW63_000713"
     CDS             5067..5936
                     /locus_tag="IVW63_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HAP7859011.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="IVW63_000714"
     CDS             6101..7372
                     /locus_tag="IVW63_000714"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAP7859012.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /locus_tag="IVW63_000715"
     CDS             7369..8664
                     /locus_tag="IVW63_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAP7859013.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="IVW63_000716"
     CDS             8763..9026
                     /locus_tag="IVW63_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAP7859014.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="IVW63_000717"
     CDS             9471..9920
                     /locus_tag="IVW63_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP7859015.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="IVW63_000718"
     CDS             9977..11395
                     /locus_tag="IVW63_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7859016.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="IVW63_000719"
     CDS             11395..12255
                     /locus_tag="IVW63_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAP7859017.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="IVW63_000720"
     CDS             12429..13202
                     /locus_tag="IVW63_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP7859018.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="IVW63_000721"
     CDS             13349..13714
                     /locus_tag="IVW63_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HAP7859019.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="IVW63_000722"
     CDS             complement(13862..15070)
                     /locus_tag="IVW63_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7859020.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="IVW63_000723"
     CDS             complement(15089..15367)
                     /locus_tag="IVW63_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859021.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="IVW63_000724"
     CDS             15560..16216
                     /locus_tag="IVW63_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP7859022.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="IVW63_000725"
     CDS             complement(16658..17455)
                     /locus_tag="IVW63_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAP7859023.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="IVW63_000726"
     CDS             complement(17452..18636)
                     /locus_tag="IVW63_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAP7859024.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="IVW63_000727"
     CDS             complement(18661..19908)
                     /locus_tag="IVW63_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virion core protein"
                     /protein_id="HAP7859025.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="IVW63_000728"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="IVW63_000728"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAP7859026.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="IVW63_000729"
     CDS             21888..22202
                     /locus_tag="IVW63_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAP7859027.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="IVW63_000730"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="IVW63_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAP7859028.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="IVW63_000731"
     CDS             22887..23531
                     /locus_tag="IVW63_000731"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAP7859029.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="IVW63_000732"
     CDS             23546..23875
                     /locus_tag="IVW63_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859030.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="IVW63_000733"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="IVW63_000733"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAP7859031.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="IVW63_000734"
     CDS             24863..25687
                     /locus_tag="IVW63_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAP7859032.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="IVW63_000735"
     CDS             25680..26027
                     /locus_tag="IVW63_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HAP7859033.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="IVW63_000736"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="IVW63_000736"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAP7859034.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="IVW63_000737"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="IVW63_000737"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAP7859035.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="IVW63_000738"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="IVW63_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAP7859036.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="IVW63_000739"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="IVW63_000739"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAP7859037.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="IVW63_000740"
     CDS             31684..32451
                     /locus_tag="IVW63_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7859038.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="IVW63_000741"
     CDS             32441..34483
                     /locus_tag="IVW63_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7859039.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="IVW63_000742"
     CDS             34764..34913
                     /locus_tag="IVW63_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HAP7859040.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="IVW63_000743"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="IVW63_000743"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HAP7859041.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="IVW63_000744"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="IVW63_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAP7859042.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="IVW63_000745"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="IVW63_000745"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAP7859043.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="IVW63_000746"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="IVW63_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAP7859044.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="IVW63_000747"
     CDS             39330..40412
                     /locus_tag="IVW63_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAP7859045.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="IVW63_000748"
     CDS             40412..41215
                     /locus_tag="IVW63_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAP7859046.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="IVW63_000749"
     CDS             41285..42025
                     /locus_tag="IVW63_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP7859047.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="IVW63_000750"
     CDS             42036..43040
                     /locus_tag="IVW63_000750"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAP7859048.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44782)
                     /locus_tag="IVW63_000751"
     CDS             complement(43085..44782)
                     /locus_tag="IVW63_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859049.1"
                     /translation="MKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLE
                     KPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTL
                     TVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMY
                     KQKRLEYSLILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYY
                     WSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLAC
                     IGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISY
                     NLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLM
                     HTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLP
                     EELPINDDDLAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYD
                     TNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14414 a         7827 c         9340 g        13266 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg tgcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataaca
//
LOCUS       DACCVZ010000014        44830 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.014, whole genome shotgun sequence.
ACCESSION   DACCVZ010000014 DACCVZ010000000
VERSION     DACCVZ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.014"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..1008)
                     /locus_tag="IVW63_000752"
     CDS             complement(<1..1008)
                     /locus_tag="IVW63_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP7859050.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1188..1532)
                     /locus_tag="IVW63_000753"
     CDS             complement(1188..1532)
                     /locus_tag="IVW63_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAP7859051.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1525..1959)
                     /locus_tag="IVW63_000754"
     CDS             complement(1525..1959)
                     /locus_tag="IVW63_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HAP7859052.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2097..2834
                     /locus_tag="IVW63_000755"
     CDS             2097..2834
                     /locus_tag="IVW63_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7859053.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2827..4038
                     /locus_tag="IVW63_000756"
     CDS             2827..4038
                     /locus_tag="IVW63_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7859054.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4245..5024
                     /locus_tag="IVW63_000757"
     CDS             4245..5024
                     /locus_tag="IVW63_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HAP7859055.1"
                     /translation="MEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAAL
                     SREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLKT
                     MLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHGD
                     VNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDEM
                     LEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5094..5756
                     /gene="trmB"
                     /locus_tag="IVW63_000758"
     CDS             5094..5756
                     /gene="trmB"
                     /locus_tag="IVW63_000758"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAP7859056.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5854..7608)
                     /gene="ade"
                     /locus_tag="IVW63_000759"
     CDS             complement(5854..7608)
                     /gene="ade"
                     /locus_tag="IVW63_000759"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAP7859057.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7740..8669
                     /gene="cpaF"
                     /locus_tag="IVW63_000760"
     CDS             7740..8669
                     /gene="cpaF"
                     /locus_tag="IVW63_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAP7859058.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8626..9675
                     /locus_tag="IVW63_000761"
     CDS             8626..9675
                     /locus_tag="IVW63_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HAP7859059.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9672..9950
                     /locus_tag="IVW63_000762"
     CDS             9672..9950
                     /locus_tag="IVW63_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAP7859060.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9925..10395
                     /locus_tag="IVW63_000763"
     CDS             9925..10395
                     /locus_tag="IVW63_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAP7859061.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10412..10714
                     /locus_tag="IVW63_000764"
     CDS             10412..10714
                     /locus_tag="IVW63_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859062.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10731..11102
                     /locus_tag="IVW63_000765"
     CDS             10731..11102
                     /locus_tag="IVW63_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HAP7859063.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11074..11433
                     /locus_tag="IVW63_000766"
     CDS             11074..11433
                     /locus_tag="IVW63_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859064.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11605..12612
                     /locus_tag="IVW63_000767"
     CDS             11605..12612
                     /locus_tag="IVW63_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7859065.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12637..13821
                     /locus_tag="IVW63_000768"
     CDS             12637..13821
                     /locus_tag="IVW63_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAP7859066.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14258..15841)
                     /locus_tag="IVW63_000769"
     CDS             complement(14258..15841)
                     /locus_tag="IVW63_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP7859067.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16419..16562)
                     /locus_tag="IVW63_000770"
     CDS             complement(16419..16562)
                     /locus_tag="IVW63_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HAP7859068.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16785..17264)
                     /locus_tag="IVW63_000771"
     CDS             complement(16785..17264)
                     /locus_tag="IVW63_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP7859069.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17337..17621)
                     /locus_tag="IVW63_000772"
     CDS             complement(17337..17621)
                     /locus_tag="IVW63_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859070.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17699..17893)
                     /gene="ssrS"
                     /locus_tag="IVW63_000773"
     ncRNA           complement(17699..17893)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="IVW63_000773"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17965..19251)
                     /locus_tag="IVW63_000774"
     CDS             complement(17965..19251)
                     /locus_tag="IVW63_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAP7859071.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19389..20060
                     /locus_tag="IVW63_000775"
     CDS             19389..20060
                     /locus_tag="IVW63_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAP7859072.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20026..20514
                     /locus_tag="IVW63_000776"
     CDS             20026..20514
                     /locus_tag="IVW63_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HAP7859073.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20527..21474
                     /gene="prmA"
                     /locus_tag="IVW63_000777"
     CDS             20527..21474
                     /gene="prmA"
                     /locus_tag="IVW63_000777"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAP7859074.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21475..22239
                     /locus_tag="IVW63_000778"
     CDS             21475..22239
                     /locus_tag="IVW63_000778"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAP7859075.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22472..24685
                     /locus_tag="IVW63_000779"
     CDS             22472..24685
                     /locus_tag="IVW63_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAP7859076.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24696..25142
                     /locus_tag="IVW63_000780"
     CDS             24696..25142
                     /locus_tag="IVW63_000780"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAP7859077.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25313..26572
                     /locus_tag="IVW63_000781"
     CDS             25313..26572
                     /locus_tag="IVW63_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HAP7859078.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26661..27608)
                     /locus_tag="IVW63_000782"
     CDS             complement(26661..27608)
                     /locus_tag="IVW63_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAP7859079.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28002..29294
                     /locus_tag="IVW63_000783"
     CDS             28002..29294
                     /locus_tag="IVW63_000783"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAP7859080.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29309..31078
                     /gene="aspS"
                     /locus_tag="IVW63_000784"
     CDS             29309..31078
                     /gene="aspS"
                     /locus_tag="IVW63_000784"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAP7859081.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31187..32062
                     /locus_tag="IVW63_000785"
     CDS             31187..32062
                     /locus_tag="IVW63_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP7859082.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32328..34211
                     /locus_tag="IVW63_000786"
     CDS             32328..34211
                     /locus_tag="IVW63_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAP7859083.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34286..34570)
                     /locus_tag="IVW63_000787"
     CDS             complement(34286..34570)
                     /locus_tag="IVW63_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAP7859084.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34560..35294)
                     /locus_tag="IVW63_000788"
     CDS             complement(34560..35294)
                     /locus_tag="IVW63_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAP7859085.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35423..36046
                     /locus_tag="IVW63_000789"
     CDS             35423..36046
                     /locus_tag="IVW63_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAP7859086.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36238..37359
                     /locus_tag="IVW63_000790"
     CDS             36238..37359
                     /locus_tag="IVW63_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAP7859087.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37366..40494
                     /locus_tag="IVW63_000791"
     CDS             37366..40494
                     /locus_tag="IVW63_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HAP7859088.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40513..43707
                     /locus_tag="IVW63_000792"
     CDS             40513..43707
                     /locus_tag="IVW63_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP7859089.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43853..44560)
                     /locus_tag="IVW63_000793"
     CDS             complement(43853..44560)
                     /locus_tag="IVW63_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP7859090.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        14381 a         7961 c         9407 g        13081 t
ORIGIN      
        1 ttttgatgaa tcagttgttt cttcagttga agattctttt gttgaatcag ttgattttgt
       61 gtcagaactc tttgttgaag ctgtagtttc acttgagtct ttcgtacttg atgaagttgt
      121 tgtgaatgca ctcaacacat tttcaaaggc atcatctttg atttttacat ttgcatcttt
      181 taattcttca ccgattactt tagttgtgaa tgcattgtca cttagtttag tttcagtagc
      241 gatatctttt agttgatctt tgtatttatc catgtcattg cctttatttt ggtttttcac
      301 cattttgaca acgtagtatt ctgtcgcata agaagtagga tttgttgtag taataacatc
      361 ggagatctca ccgtctttca atttgaaagc tgcttctttt acttctgcag gaatagttgt
      421 tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt gtctctgtat cagttgattt
      481 gtctttggct aatttagaga aatcatctcc atcatccgct gattttttca catcttttgc
      541 ttcatcttca cttgataatt tgatgatttg tgcttctact tctggatgga aagatttcca
      601 agcagttttc aaatcgtcat ctgtaatatc tacgtgagct ttcaagccag cttcaaaagc
      661 taaattgtta cgaatatatt ctttataagt atctttcgta tatccagcag cttctaattg
      721 tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg tattctgcat ccacttgctt
      781 atcggttact ttatcgccat atttgttatt gaatacttta taaatgatca tccgttgtac
      841 taaggattgg ttcgatgatt caagttttgc ttcatcatag aaatcagata cagtgatcgt
      901 tccgcctttc atcgttgcga tatctttatt agtatcgcct gaacaagctg ctagagttaa
      961 aacagccaac gcactagtag ctgccaaaat aattgatttt tttttcatta aaatttgcac
     1021 tcctgtaatt agttattatt tttatatatt aactatacca tatcccattt cctttaaaaa
     1081 cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc acattcctag gaaatacgca
     1141 aacttttctc acttatatag ttaaatctgt tgagaaaata atcattatta tatttgttca
     1201 ggatactctg gcagatcagc ttttagtttt tctacttgtt cattgatttg tgtgatacgt
     1261 ggttcggctt ggaatttaaa atcttcgata tcttttttga ttgcttcttg gaaagcagga
     1321 atcacagatt cagctgtttc ttttgtttcg atcaatgcgc ttttaaaatg attcaggctg
     1381 ttatttaaat catttgtcag agttgttgct tcttccaatt cttcgatcag tttctttctt
     1441 gtttcattcc cgctcctggg cgccaataac agacctccga cagtgccagc agcagctcca
     1501 aataacagtc ctttgaaaaa gtttttaatc atcgcaggac acctgcttta cgattgtttc
     1561 ttgaatagct tttagttctt ccgatccata actatcttga tgattgacaa agtgaataga
     1621 aaaatcatcc tctttgctgt agcgagggac taaatggata tgtgaatgaa aaacagattg
     1681 ataggctagt tcacggttgt tattcaagat attaagacct ttcatttctg gaaaagcttt
     1741 ttccaatgct tgagcaatct taggcacacg cgaaaaaacc tctcctgcaa gttcgggatc
     1801 atattcaaaa atatctgcta catgacgttt aggcacaact aatgtgtgtc ctttcgttgc
     1861 ttgagagatg tctaaaaaag catagacctt gtcgtcttca tatattttat agcttgggat
     1921 ttcttgattg atgattttgc aaaaaataca gttttccata taaaacatcc tttctataaa
     1981 gaataaatac ttcagcttaa ctttaccata agttaaagct attgtaagga aaaaaacaaa
     2041 ataccgtcat tttcttcgtg gtataataaa taaaaataaa tggcggagga aaaagaatga
     2101 gtttaattat cgatcatgtc acaggggggt acggacatct ccctgtgtta aaagatatca
     2161 gtttcgatgt acagcctgga gagatagtag ggttgattgg actgaacgga gcagggaaaa
     2221 gtacgaccat caagcacatt atcggtctgc tggaagcttc aaaaggaacg atagaaatca
     2281 atcatctatc cttaaagaaa aatacggaag aatatcgcaa acaaattggg tatattccag
     2341 agactccttc tttatatgaa gaattgacat tgagagaaca tatcgaagtc actgcgatgg
     2401 cctacgatat acctatggat atagcaatga aaagagcaga aaagttgttg gagacttttc
     2461 ggttatctaa tcgtcttgac tggttcccag ctaatttttc aaagggaatg aaacagaaag
     2521 tgatgatctt atgcgccttt ttgatcgagc cttctttata tatcatcgac gaaccatttt
     2581 taggcttgga tccactagct atcaatgcat tgcttgaatt gatggtagaa atgaaaaaag
     2641 aaggagccgg tattttgatg tctacgcata ttttagctac tgcagaaaaa tattgtgatc
     2701 gttttgtggt cttacataac ggagagatac gagcagacgg ttctcttgag atgttgagaa
     2761 aagaatttca gctgccggat tcttctttgg acgaaatcta tattgcttta acaaaggagc
     2821 aggcacatga gtagtttttt tcaaaaacgt ttagcaagac atcaaaagaa aatgatgaaa
     2881 tatatgcgtt atgtattgaa cgatcatttt gttttagttt gtcttttctt gattggcggt
     2941 gtgggattat attattctaa ttggttgaaa accctgcagc caccgtttgc aattggaggg
     3001 ctcataatct ctgtattttg gatgctctgt ttattcgtgg gtaagatggc tacttttgca
     3061 gaggcagcag atattgtttt tttacttcct aaagaaaaag aaatgcaaac ctatttggaa
     3121 cgagcttttc gctattcttg catttttccg ttgatctttt tgatattggc atgcggattg
     3181 gccatgccat tagtggtggt tagtacggag caatcctttt cgatgttttt cgtctatctg
     3241 atcatattat ggagtttgaa attcagtcat ctgcaaatca agagagcaga attgtttcga
     3301 ctagatcaac aagttattcg ttattggaaa ttaggctggt ttttttcttc tctgatcttt
     3361 ttgtttctat cattttattg gctaatatgg gcaggaatag caggtgcatt agtacaggca
     3421 agtctatatt actggttttt gtggaagcaa caagaaaaag gattggattg ggagaaaatg
     3481 gtgcatgtag aagaacatag gttgcatcag atctatcaat ttatcaattt attcacagat
     3541 gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt tggatcctat attgactcat
     3601 attaaaagag aatcaaaaaa cacttatctt tacttgtttg caagaagatt ggcaagaggt
     3661 tctgatttta gtggtcttta tttccgatta gtaattatag gtgggttatt gattgccgga
     3721 gtagtcgact tttattttag tctgattatc ggtttcttat ttttatattt gatcggtttc
     3781 caactgttac ctttagcgaa ccagttccgc tatatggttc tcgttcagct ttatccaatc
     3841 cataagaatc agaagaagca ggcgattcag tatctactca catgggtatt aattatcgcg
     3901 tcggttattt ttggtttgat tgctgcagtc gtattagatg ggcagcagcg atgggttccg
     3961 ctagcggctt atttgattgt tactatgctc tttgttaaac tatatgtacc aactcgtttg
     4021 aagaagatgt cagactgaaa acaaagctgt gtagggtaaa aatgagaatg aaaaatagag
     4081 cgttgacagt aagaatgctg ttcgttctat tttttttgag aaaagctggt tttttgaatg
     4141 gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta gtgttcaggc gactagaata
     4201 ataagtactg caaaacaaag agtaagagga cgggagaatg catgatggag tttcagttag
     4261 accaagagtg gcggttacgt cccatcaaag gcgacacagg aaaaacatac ataggcatgc
     4321 gtgatgagga caaagtcttt attaaacgaa acacgactcc gatgttggct gctctttcaa
     4381 gggaaggaat tacaccaaaa cttgtttgga caaaacgaac ggggaatggc gatactttga
     4441 cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa tgagattggt caaagaaacg
     4501 acgtgattga tgttttgtac catttacatc attcaaattc tcttaaaacc atgctgaccc
     4561 gtatcggtgg tcgtgtcatg acgccggaga agatgctgca aaaatatgaa aaagaattac
     4621 cggaagaact ccagaaaaat caatttctgc aaattgtcca tcgttttctt cgtgagcaga
     4681 tcccgtcaat agataaggaa aacttatcag tagtacacgg agatgtaaac catcgtaatt
     4741 ggttagtatg taaaaattat ttatatctag tcgattggga ttcaatcatg tttgcagacc
     4801 ctgcggtgga tattgcaacg attttaggaa attatgtgcc actgtctagc tggaatcagt
     4861 ggctgatcag ttatggcata cgcccgactg acgaaatgct tgaaaaattt cattggtatg
     4921 cggccatgaa tttgctccaa gaaatcacca gatattgcaa acgtgaagat catcgacgga
     4981 tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg ctgaggtttg gcccaaactc
     5041 tgcggagatt tggccagacc tttttaatta gaggaaagga atggagataa ataatgcgtg
     5101 tccgaaatcg tccgggagca gcggaaatgt tagcggctca cccgaatttt gtaattagtg
     5161 atccaacatt gtggaaggga aaatggaatg aattgtttga aaacgatcat ccaatccaca
     5221 ttgagattgg tatggggaaa ggccagttca tcactggaat ggcaaaagcc catcctgaaa
     5281 tcaattatat tggagtagaa atgcaggtca gtgttgtttc gattgcacta gacaagttga
     5341 tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga tggatcagcg ttgacagagt
     5401 atttcgctga cagcgaagta gatcaaatct atctgaattt ttccgatcca tggccaaaaa
     5461 aacgtcatga aaaacggcga ttgacatata agacttttct tgctgtagat gaacagattc
     5521 ttcgtccaaa tggagaaatc catttcaaaa cagataatca aggattgttt gagtattctc
     5581 tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt atggttagat ttacatcaaa
     5641 gtcaatttga aggcaatatt atgacggagt atgaagaaaa attttcttca aaaggtcaac
     5701 gtatttatcg agtagaagct caatttcaag ataagaccaa aaagaaaagt ctgtgaaact
     5761 aactttctgc tttcataaaa acattaatat ccataaataa atcccagaaa atgaacatta
     5821 cagatgtaat gtattttctg ggatttattt gatttaaaat gtatttattt catcggtttt
     5881 tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat aatcctttgt cggtgatctt
     5941 caattcgggt atgacagata atgttaagaa agaaagtgtc aaaaaaggat caaaggtttt
     6001 agctgctcct agttgatgtg ctttagttat taattcattc aactgttcat agacgatcga
     6061 aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa acacaagcta tttcctgctg
     6121 attgttgaca acggtcatcc cgccaccttt ttgaatcaaa agattagcag catacagcat
     6181 atcctcgtcg tttgtcccaa cgacaactag attatgcgag tcatgggcaa tcgttgtcgc
     6241 tatcgctcct tgtttcagct gaaatccttt cactatgcct aatccaatgt ttcccgtttg
     6301 atggtgacgc tcgatcaccg caatctttaa ttggtctttt tcgattgaag gaatgaatcg
     6361 ttcgccttgt cggtccactt tttctaccaa atctttagtc actagactat tcgggataat
     6421 ttcgatcaca tgggcttgtg aagaagaaag aagcagctct aacgaatgtg gatttaatgg
     6481 ttgagcgttt agttttggca gacaacacgt atatgaattt gaatgatcag caaataaatg
     6541 gtcttggagt tgcccagatt gaacaactaa tgttccctta tagaaaactt catgaattgg
     6601 cagcttggta agatcgtctg ttaagaagaa atcagcttga tacccagggg caatcgcacc
     6661 tagtgttttc aaatcaaaac attctgctgc attcaatgtt gccatctgaa tggcttgtaa
     6721 tggatcgatt ccaagtgcaa tagcttgacg gacgatatga tcgattgatc cttcttttac
     6781 taaatcattg atcagtttat catcggtgac aaagaagcat cttcttgaat tttcaggtgt
     6841 gatcgccggt agtagcgatg ccagatcttt tgcaacggtc ccttctcgaa ccattaaata
     6901 cataccaaga tccaaacgtt ctttagcttc ttttgcagtt gtagcttcat gatccgtccg
     6961 aatacctgct gcaggataaa catttaactc ttccatgccg ataccagctg catgcccgtc
     7021 aatttttttc ttatgctggt gcatcaattg gatcttttct aggatgtctg tttcattatt
     7081 tgctactgct tgatagttca tgacttcagc taagcctaaa acttcgggtt tttgtaaaaa
     7141 aggggctaat ttttttgcat ttaaatttgc accattggtc tcaaaagggg ttacaggtac
     7201 acaagaaggt agcataaaaa agatattcat gagtgtttgt cttgcatctt ctatcataaa
     7261 ctcaagacct gtactcccag caatgtttcc tatttcatgg ggatctgtca ctacagtagt
     7321 aactccatga agcaaggata cttttgaaaa ttcgcttggt gataaaagtg agctttcgat
     7381 atgcacatgg ccatcgatga atcctggcac tagatattgc ccattagcat tatgtacgct
     7441 ttttccttcg tattcaccga ttcctacgat cattccttcg cagattgcta catctttttc
     7501 catgatttct ttcgtaaaga cgttgacgat cttagcatgc ttgatcacta ggtcagcagg
     7561 ctttttttta cttgctactt cgatatattt ccttaatgtt gtttccaatg gagtgcctcc
     7621 caagataaat ttttataagt ataacataaa ttcggttttt gccaatattt ttttgtaaat
     7681 tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt ttttgtggag gggagaataa
     7741 tggaaataaa acgattatcg gatcaaatga taagtgaaag ttttgccaaa catgcccaag
     7801 acgtatatat attgccagct tcagaagtat tttacatcta ttttcgctat ggaaaaaaac
     7861 gaacattctg gaagaaagtc tcttcggcag atggacagca actgatctca agatttaagt
     7921 atttgggaca gatggatatc ggagaaaaaa gaaaagctca gttaggtgca tttacttatt
     7981 ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt aggagattac cttcaacgag
     8041 agagtttagt gattcggcta ttatacggta cttttgaaac accccatcgt tgctttagtt
     8101 ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg tggattatac cttttcagcg
     8161 gaccagtcgg atcaggcaag acttctctaa tgtatcggtt ggctttggaa gaaaaattgc
     8221 aagtgattac tatcgaagat cctgtagaga tagaagaacc gttttttctg cagctacaga
     8281 tcaatccgaa aatagcacag acttatgata cacttttgag actcgcatta cggcatcgtc
     8341 cagacttgct aatcattggc gagataagag atgaatcaac tgcacatgct gcggtaagag
     8401 cagcactaac agggcaccgg gtttttgcaa ccgtacatgc acgcaatctt gaaggtacat
     8461 tggtcagaat ccatgaactg acaaagaaaa aagaagagct atctgaatgt ttagctggtg
     8521 tcatttatca agaacttttg gaagatgcca atcaccatcc ttctgtttta tggagttatc
     8581 aatttatgga ggaagaatca gtaaaaaaat catgggagga aagttatgaa gaagctcagg
     8641 aaaatatttg gcagtcagaa ctattctaaa ggattaacaa gaagccagca aaaccagttt
     8701 gcacaaacca tgggagaact gcttttatct ggttttagtc tgcaagaatc cctttattta
     8761 ttactcacga tccgttcgtt tccacctgtt attttggcaa atatccaaca tcagctaaag
     8821 gaagggcaag cgtttagtga ggtactttcg caaataggat atggagcaga gcaactggta
     8881 cagatcgagt tagctgaacg tcatgggaat ctgccgacaa ctttgttgga aattgccaaa
     8941 cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa agctgcttgc atatccgatg
     9001 ctattgctca cctttttgct aggtatcttg tttagtatgc ggttgttcgt tttgcctcag
     9061 cttattggtt caggaatggt catgcaagag cattggggta ttcagctgat acaagtcttt
     9121 cattggtatg ttctactatt catcctagcg gttactctat tggctttact agtaaggtat
     9181 cgtctgatga agttgtctcc tgttgatcag agtgaatgga taagcagaca attattgatt
     9241 ggaccgatat attccttgta tcaatcggct tatttgtcac tagagattgg aaagcttttt
     9301 catgaaggtt tcgaattaag gcaaatcata gtctgcttaa aggaaacgaa acaagaaagt
     9361 ctgattcagc atcttgcctc taagttgatt caaggattgg aggcaggtat gtcattggct
     9421 gagcagttcc agaattatcg ttttctatca gaagaattca gtaaaattgt tttacaggga
     9481 gaggcaaagg gaagtttagg taaagaactg attttttaca gcgaatggac aagaaaacag
     9541 cttttcaaac gtcttcatca ctggatgcat tttattcagc caatcatttt tttgggcgta
     9601 gcggctttga ttttattagt ttatgccgct gttttattac ctgtttacgg aagcatagag
     9661 gaggttttgc catgaaaaag agaaaaatat cttattatag cggttttaca ttgatcgaaa
     9721 tgctaatcgt cttactgatc atcagtgtat tagtgttgtt gttcgtccct aatttgtcgc
     9781 gttataggaa tcatgtagac caagaaagtc gtgaagcgat catccagttg gtagacacac
     9841 aaaaagagct ctatgcgctt caaaataatg gaagagttcc tactgtggag gaattgttga
     9901 atgaaggcta tatcaaacga gaacatgcag aaatctatca gcggccttga aggtaaggtt
     9961 ttagcatcag gatatacgtt gtttgaatca ctcttactga ttttattact tacaacgatc
    10021 ctttcttttc cagttctcgc attttctgca tggaagaatg aattggcagt ctatcaattt
    10081 ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa tcgctattgt gaatcagatc
    10141 caaacaggct tttattggaa tagtgaagag aatcaaatca tttttcatgt tccgaatcca
    10201 gataaaataa attgggaagt attagatatt cctgatgaga ttaccttgaa acgccatgct
    10261 tctattactt ttgctgctag aaccgggaat gaaagttcac taaaagctta tcaattttat
    10321 tgggaagaaa aagagcggac gattacgtat caattccaga tagggagtgg tcgctataca
    10381 aaaagaattg aataaaacag gatttgtttt gttggagtcc cttacagcgc ttatgatcgc
    10441 ttctgtctgt gtctacttag tgagctttgg ccagctgttt ttgcttcagg cagaaaagaa
    10501 aagtggggag gaactgctat ttattcgaat gatttatgaa gatatcaaga cgcagcggat
    10561 gtatcacaaa agaccagagc gaagggaaga aatgatccca tacgatatcc aaattgtcga
    10621 taataatgga gtaatcgaaa aagtgtttgt caatatggag aaagaagcga tcagtattga
    10681 aaaaacaagt aattccagca tttacgctga ttgaatgtct aattggactg atgatattga
    10741 gcagtctatt gctcacattc aatcttttga ttcagcaaac catccaagta agtgaatttt
    10801 tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc acaattagaa gaagaactca
    10861 agagcagtca caatgtctct gtgaaaaatc agcaactgca ctacacgatc gaggataaac
    10921 agtatatcat cgaaagatat caggcaatga tacgtaaaag aagaacttcc ggcggacatc
    10981 aacctatgtt aacaagtatc actgagcttc aattattgga aaaagaacac acaatttctt
    11041 tttatgtaca ctttgaaaat ggagaagatg gatatgccat atggacaaaa aacgatcagt
    11101 agaaaatgtt ataagggctc tattttattt tctgtcttgc ttttatttct tttatgtacg
    11161 tttttattga tggcagcatt agaaagctac cgtttgtcaa tggatcttaa tatacgaatc
    11221 aaaaattatt atatagcaaa aataatgaag cagatggctt tatcggaaca gtctacgctt
    11281 gccgaaagtt cggaaggagt tttttactac acaactggat ctgtaacata tcagtgggta
    11341 caacagtccc tattcttaga ggtggaagtc tcaccgttta tctttcggtt cacagaagaa
    11401 gtaaaaaatg atacagatac tagtacagaa tgatggaatg ttcgtgaaaa cgccctcttt
    11461 tctgttataa cactgttttt aataaaaaaa tgtttgccgt ttcacaaata aaaaacagtg
    11521 aaaacgattg aaattttgtc aattgttcga tagaattaaa caggtgaaaa aattgttata
    11581 atatatctag aaatgaggtg caccatgtta ccagaaaaaa tggaacaagg gtttaatcaa
    11641 aacctggaag ctattcagct tttacagaat gcattgggaa cttccttttt agaagcctat
    11701 gtcgaaaatg cagaaaattt aatagatgat tatcaagtac gtgtggtgga tggagtgccg
    11761 acaaaagaga caacgcaacg gatcacagct ctttatgaag agttgaagaa actttctttc
    11821 gagccagaag aatggcgcag actgtctcaa ttacttttat tgaagggcag ccagacagaa
    11881 catttgcagg cgaaccatca actcactcct gatagtatcg gttttttatt tgtttttctt
    11941 attgaacaac tatacacaaa taaaaaagca ccggttaaga ttctggatat tgcggcagga
    12001 atgggcaact tgttattaac agttctttta aacctatcga atgcggggta ccaaacagaa
    12061 ggaattggtg tggatattga tgatacattg ttggctgtcg cagcttctac aagtgatttg
    12121 acacaagcaa atgttcaata ctttcatcaa gacgggttgc aggaattatt aatagatcct
    12181 gtcgattttg caatcagcga tttgccaatc ggttattatc cgaatgacga aaaagcaaaa
    12241 gagtttttaa caagtaccga agaaggccat agttatgcac atcatttatt gctagagcaa
    12301 tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt tgatgccgag tggattttta
    12361 gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag aagaaggtta tcttcaagga
    12421 atgattcaat tgccagatga attgttccgt aataaacaat cgcaaaaaag tattttgatc
    12481 ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag tcttgcttgt gaaacttgct
    12541 tcattaaaag aaccagagaa ggtgacggaa tttttcaacg agtttaaaaa ctggaaatca
    12601 tctgctctgt aatcattcaa cgagaaggag agtcatatgt ctaaaacaat tgcaatcaat
    12661 gctgggagtt caagtttgaa atggcaatta tatcaaatgc cagaagaaac cgtagttgcg
    12721 aaagggatcg tcgaacgtat cggtttacaa gattctattt ttaccatcaa gtacggcgat
    12781 aatcaaaaat tcgaacaaat catggatatc gaaaaccacg aagtagcagt aaaaatgctg
    12841 ttagatcagt tgattgaact gcaaatttta agctcttatg atgaaatcac cggagtaggg
    12901 caccgtgttg ttcacggagg agaaacttat ggggattcag tagtgatcga tgagaaagta
    12961 atggaccgca ttgctgaatt agcagaattt gctcctttgc ataatcctgc aaacttaatg
    13021 gggatcaaag cgtttaaaaa gattttacct gacattttga gtgtggctgt attcgataca
    13081 tctttccact caacaatgcc aaagcaaaat tatttatata gcttaccggt gtcttattat
    13141 gaagatttca aagtaagaaa atatggcttc catggcacaa gtcatcgtta tgtgtcggaa
    13201 cgtgcggcaa aattattgaa caaaccgatc gaagaactaa aaatcatcac ttgccactta
    13261 ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat ccatggatac ttctatggga
    13321 ttcacaccat tagctggggt gacaatgggt acacgttcag gtgatatcga tccagctgtt
    13381 ctcccatatt taatggaaaa attagagatt gatattgatg aaatgatcaa tgttttgaac
    13441 aagaaatctg gtctgctagg cctaacagga ttgtctagtg atatgcgtga tcttgaaaag
    13501 aactatgaaa aagaacatat tcgtttagct tatgacattt tcgtggaccg catccgaaaa
    13561 tacatcggcg gttatgtgac aacgatgaat ggtgttgatg caattgtctt tactgctggt
    13621 atcggcgaga atgacggaca tgtacgtagt gaaatcatca aaggtatgtc ttggtttggt
    13681 tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag aagtagatat ctctacaaaa
    13741 gaatcaaaag taagagtatt agtgatccca acagatgagg aactaatgat tgcccgtgat
    13801 gtggagcgtc tgcgcggcta agccaaagca ttcgttagga taaaagatga aacgcatgca
    13861 agagggaatt cttgcatgtg ttttttttgc ggagaagacc gcaaaatggt aatttaactt
    13921 caatttccct tcttttttac aggatcttct tagggaattt tgcttggaaa agtggtcaaa
    13981 agggaaaaga ctggcatttt atttattgat tttcaggaaa atcccaatat tttattttca
    14041 ttcatcttta taagggacat tacatatgta aaaagaaaaa acatttttag atcagcctcg
    14101 tgggctgtcg actttattct tcgctttatg tttagctaga aaaccgatcc gaaacattca
    14161 ttgatcgaat aataaaaact tgattttcca cctgtacttt gcctgaatcg tgaaagcaca
    14221 ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta gtcaatcagt tggccgagcg
    14281 gctggcggct gatctgctcc tgatcaataa cgagtgcttc ttggaagtgt tgctgcaaaa
    14341 agtagcggtc atggctgact gctaggagcg ttccttgata gtcttgcagc atttcttcaa
    14401 tttcttctcg agcatagctg tcgaggtgat tggttggttc atccaaaatc aggacgttga
    14461 ttttttctaa aaagagtttc agcaacgcca aacggatttt ttcaccaccg gataaatctt
    14521 tgatccgttt acccacatcg ctttgataaa agccactttt ggctaattgc cgtcgagcga
    14581 cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa acggctatcg ggatcggcaa
    14641 actgcagctg ctgcggcaaa taaccgattt gcaagctact acctaatttg atggtgccac
    14701 cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt tgattttcct gcaccattgt
    14761 cgccgatgat ggctaaatga tctccacgat agactgcaaa actgctgtct ttgaatagta
    14821 cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa aacttctttg ccagattttc
    14881 caccattaga caagctttgc agccgatttt tcgggggagg tggcggtttg acgagtgtca
    14941 gtttcgccag gcggcgttcc agttctttgg cttttttgaa gaaggactca ttgtctcctt
    15001 catgtgccca ctgacgaaaa cgacgaatca tgactttcaa ccgctggact tctttttgct
    15061 gcagttcgta attttttgtc agctcagcca agcgagcttc tttcaagact cgaaaacggc
    15121 tgtagtttcc gggatactca atcaatgcac cttcttccag ttcccatgtt tttgtggtga
    15181 cttgatcgag aaattgccga tcatgagaaa cgaccagaac cgattttttt gtattctgta
    15241 aatagttttc caaccagcga atactgttaa gatctaaatg attggtcggt tcatcgagta
    15301 aaagtaaatc ggcatcggct gctaaaattt tggctaaagc gactttaact cgttcgcctc
    15361 cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat ccctaagcct tgcaagatcg
    15421 ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc aaagcgatgc tgcagctcac
    15481 cgtaacgggc cagacacttc tctaagtttg tatctggttc tgtcatcaat gcttcgtagc
    15541 gactcatttg ctgtttgagg tcctgtatct cagcggcaga atggagcaag tagtggttga
    15601 cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc gatctttaag ccttttttgc
    15661 gactgataac accgctgtcg acaccttctc tgccggtcaa gatttgtaaa aaggttgatt
    15721 tgccagttcc gttgataccg actaaggcaa ttttttcacc agcttcaatt tgacaggata
    15781 aatcctcaaa taatggattc ccgccgattg tttttttaat agaaattgct tgtatgatca
    15841 tgatctctct ccttgagacc actcaaaaag gccatggtta tccatggcct gtgttattta
    15901 aactcagatt atcatgagaa aaataccttg agatggccat tgattttacg tgaattcaac
    15961 tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa ccaattgcat ggctaaatgc
    16021 gatatggtat cgttggtaat tttcattact tgttatttta gtcatgcgca tcatagtatt
    16081 ttccctcctt cgtgtagttg tcttttccag tgtacctgaa agtgtcagaa agttcaacta
    16141 gcgctgacat ttacttaata tttatcgatg tgtaattctg tcagagagct ttttttatct
    16201 gactgagggt aatgtctcgt ggaccacatc attgtattct gagctaaacc agcgttcagg
    16261 cgaaatcata tggtgtttga taaaaaactt tgtctacatg acttcctttt gccatttgct
    16321 taataccgtt gcattaaaca gctcttctct ttggaaatct caccaacatc gcgttcagga
    16381 gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc aattcttgaa tgatttaccg
    16441 aatgtagcac ttgccttctc gcggtacccg aacccgaaat aaaattttag tttggcgata
    16501 aaatcggtat ccgccatcga tacttcatat tttttcgtat cagattcatc ggaaacttcc
    16561 acattgacga accaataagc tttggcatgc ttaggtcgtt ttaaaccaca ccagggcgac
    16621 taatcgccct ggtgttcact tttttttatt ttacttgaac tcattgactg ttttcccttt
    16681 attttaaaca ttataaagac cgatgagtgc ttgccgcgtc ttttgttttt atcacggttt
    16741 tttgtgcaaa aaaacctgcc gatagttggc aggtcgtcta cgtgttaagc tttggtgtgg
    16801 tctttagctg gcaattggtt ttctaaatca gttcggacaa caagcacatc gcaagctgcg
    16861 tttctaataa catattcaga aacagaacca ataaataaac gttctacagc attcaatcct
    16921 gtggctccta acataatcaa atctacttga ttatcttctg ggatttctct ggcaataatt
    16981 tgttttggtg agccatattc tacgacagag gttacattat tcaagccagc tttcttcgca
    17041 ttgctttcat aatctgccaa tgtttgcttt gccatttcag tagcttgttc tgcaagcatt
    17101 ccatcaaagg atgaaacggt ttggaaagaa cgtgtgtcaa tgacatgtgc taatagaagt
    17161 tctccgttat ttcggatagc tacattgacc gcctttttaa aagctaattc agcttcatca
    17221 gaaccatcta cggcaaccat gatttttttg tattgttgta acataagcat tcactcctca
    17281 agtcaatcgt attgtactct tttattgtag aacactttag ggaaaaagag aattatttac
    17341 tgctttggtt cagcaatttt ttttgcaaat cggatactga aggtggcaga aacaataatt
    17401 acgatcagta aaaagaccaa ggcaataaag cgttgattga aaaaagctgt taaaataccc
    17461 attacgccta aaacagcata tgcagctccg taaaattgta ggaatccttg atttttatca
    17521 tttttgttga tcaatacaaa aaagatatcc tgtttattaa ataaataata gctaacgaat
    17581 aataatacta aagtggcgat aatcattaaa atcctaatca tgaacaaatc ctccaaaata
    17641 agcaacaaat agaaaaagca atttgccaag agcaaattgc tttattcttt aaaagatggt
    17701 aatctccgtt aatgccgttg tttgtcctgt agtattgatc ccgcgaattc aagcaggtgg
    17761 gtcccatggt cgtagcttcg aactaccaaa tgataaggca tgttaccagc agtgacacaa
    17821 gacgggtccc aagatatcaa taaaaatgtt cggtcaacac acaaagagga caattcgaac
    17881 atcacagatt tcccacctct atagtagcat atgaatttaa aaagagcaat gagagagctc
    17941 gcagaaacag aaccgttttc ttgtctagtt ttttggagga tgctttttcc actcttttat
    18001 acggtaatac tgttgaccca gagcctgttc atatttccct gtatcttttg gctgataata
    18061 ctgagcattc ttcagtttat ctggtaaata ttgctgattg acccaagcct gatcaaaatg
    18121 atgaggatac tgataaccca cgccacggtt gagtgatttc gcacctttgt aatggctatc
    18181 tctcaaatga tcaggaacat ctccagcttt gccctctcga atatcagcaa gtgctgcatc
    18241 taatgccatg taggcagaat tggattttgg cgacaagcaa agatcgacga cgacgtctgc
    18301 tagtgggata cgtgcctcag gcaatcccaa tttttcagca gctaatacag cgttcactgt
    18361 acgagccgca gcagcaggat tacctaaacc tatatcttca taaccgataa ccatcagacg
    18421 ccggcaaata cttgccagat cacctgcctc aactaaacgg gcgagataat gaagtgcagc
    18481 atccacatca cttccacgaa tcgatttttg aaaagccgaa ataacgtcat aatgagcatc
    18541 tccatttttg tcatgggtaa gagcttttct ttggacacat tcttcaatga tcgacagtgt
    18601 aagatgaatc cttccttctt tatctgaagg agtcgatagt gtagccagtt ccagcccatt
    18661 caatgcactc cgcaaatcgc cgttcgttgc acgcgaaagg tgaagaagag catcttcgtc
    18721 taactggatt gcttgttgtc caaggccgcg ttctttatcc cttaaagcat gttcgactgc
    18781 caactggatg tcttgttctg ttaatggttt gacttcaaag atctgtgtac ggctgcggat
    18841 cgctggattg atggtaatat aaggattctc agtagtcgct ccgatcaaga tgattcggcc
    18901 actttctaaa tgaggaagca gaaaatcctg ttttgtttta tctaatcggt gtacttcatc
    18961 caataagagg atcactgtac cactcatttt tgcttcttcc gctacaactt gtagatcctt
    19021 ttttgaatct gtagcggcgt ttagcatgcg aaatgcataa ttagtagagc cggcgatcgc
    19081 acttgcgata ctcgtttttc cagtaccagg aggtccatat agaatcatgg aagagagcat
    19141 gcgagcatcg accatgcggc gtatgatttt tccttccccg actagatgct gctgaccaac
    19201 gacttcatcg atcgttcgag gtctcatgcg ataagccaat ggctgttgca taggattttc
    19261 ctccttcttg tttttacgtc ccttaattat atcatattta gcaagatgcc tagaaagaac
    19321 agccttctgt tgttttgttt tcatagctta tccaactaat attgtgtatg ataaagtagg
    19381 tgagaaaaat gacggataaa caaaagatag atgaattttt ttggaataaa acgacgccag
    19441 aagtggcacg ggatttattg gggatgtatt tggagcatga cacaccagaa ggaagattag
    19501 ctggatatat tgtagacgcg gaagcatacc taggtccaga agacgaggcc gcccatagct
    19561 atggtttaag aagaacaccg cgtgtgcggg caatgtatga aaaaccaggt acgatctacc
    19621 tttacacgat gcatactcat cggattttga acatcattac tcagccagaa gggattcctc
    19681 aaggagtaat gatacgtgca atcgaacccg ccgcaatgat tgatcaaatg agtaaaaatc
    19741 gtggcggaaa aactggtcca gatatcagca acggtccggg aaaattagtg gaagcattag
    19801 caattcctca agaactttat ggtcagtcta tagcagatag ttcgttacgc ttagtttttg
    19861 agaaaaaaaa gacaccaaaa aagatcaatg ctttgcctag aatcggtatc ccaaacaaag
    19921 gtgtatggac agaaaagccg ttgcgttttg ttgtgtcggg aaatccttat atctctttac
    19981 aaagaaaaaa ccaaatcgag aaagattggg gttggaggaa agaaaatgaa aaagaaggat
    20041 ctattaacat atttagatga aataattgaa aaacaagtga cagactatga tgtagcttta
    20101 gattgggata caaaaaatca tacgatcgag atcgttgttc gcttgtttgc agaaaataaa
    20161 gcacaatttg agattgatga tgcagaaggg atcgtttcgc aagaaccaat tatcgaattt
    20221 gaagacggcg tacttctttt taatcctcag aaatctgttt ttgatgaacg caattatcta
    20281 gcagtaatcc cttatgaagg aaaaaaaggg ttggcaaaat cagtagctga ttctttagtg
    20341 gaatatctaa atgaagtatt agctcaaggg caaagcgatt tgcttgattt tttggatgaa
    20401 gacgatgacg aagctgtatt cgagcttcac tgggataatc agcaactagc agaattagta
    20461 gaagtaaaac agcaaaatga agcagatact tatttaccgt acccaagtta ttaaggagtg
    20521 acagatatga aatggaatga agtaaaagta gaaactgaaa gtgaagcagt cgaagcagtt
    20581 gctaatattt tgatggaggc aggggcgagt ggtgtcgcga ttgaagattc tttagatgtt
    20641 gaacattttc agtcggatca atatggtgag attttagata aaaatgattt tacatcgctg
    20701 aaagaaggcg cactagtcat ggcttatttt ccggaaacga ctttcttacc ggaaatcttg
    20761 ccttttatca aagatcgtat cacacaatta cctgagtttg gtctagctat tggaaaaaat
    20821 aaagtaacag ttagtgaagt agaggaaagc aactgggcaa cagcctggaa gaaatactat
    20881 catccggtgc gtattacgcg aatgctgacg gttgcgccaa gctgggaaaa ctaccagaca
    20941 gaagatcctc tagaaaaaat tatcacacta gatcctggta tggcatttgg cacaggcact
    21001 catcccacga cttccttgac attgacagca ctagaaacag tcttgcgtgg tggtgaaaca
    21061 ttgctagatg tgggaactgg gtcgggcgtg ctaagtattg cagcaaaata tcttggtgca
    21121 aaagatgtct atgcctttga tttagacgaa gtagccgttc gttcggcgaa agaaaatatg
    21181 gatatgaatg aaatagccaa agatgtccat gtatcagcta acgatctttt gacaggaatc
    21241 gagattgaaa gtgatgtaat cgttgcgaac attttagcag atatcatctt attgatgatc
    21301 ccagatgctt ggcgtttact gaagcaaaca ggcacgctga tcgtttcagg aatcattgaa
    21361 gagaagaagc aaatggttct ggatgccatg ttagaacaag ggtttatcgt ggatcaaatt
    21421 ttccagcaaa aagactggta tgcaattatt ttgaaaaaac cagaggtgga atagatgcag
    21481 cggtattttt taaaagaatc atatgaatca aaagactatt ttgttttaga aggggaaaac
    21541 tatcaccaca ttgtacgggt tatgaggatg gaacccgagg atgaagtttt tttggcattc
    21601 aatgatcaaa tagccattgt tgcagaaatc acggagatta ctgaagaggc tgtttatctg
    21661 aaagaaatta aaaaagaaga aaatcaaaag gaactgccaa gttcgattac catagcgagt
    21721 ggctatccta aaggggaaaa gctggattgg atcgttcaga aatccactga attaggagcg
    21781 caagcttttc ttggtttccc ggcatcagcc tctgtcgtta aatgggatgc aaaaaaacgt
    21841 atgaaacgac aacaacggct tgaaaagatt gctcaagagg cagcggaaca atcccatcgg
    21901 cagatcgtgc catcagtaga gttattggaa acgaaacaag atttatttga gcggctagat
    21961 gattatgacg tggtcttggt tgcttatgag gaatcagcaa agcaaggcga aaaatcaaat
    22021 gcagccaaaa ttcttagtga aacaaaacca gatagtcgaa tcttagctgt ctttggacca
    22081 gaaggtggat tatcccgcga tgaagtcgat tattttgtag aacacaaagg gatactttgt
    22141 ggattaggac caagaatcct tcgtacagaa acagcacctc tttatttatt aagtgctgct
    22201 agctatcaat gggaattaat gaatccttct ttcagctaac gttcttcatt aataaaagag
    22261 tatcgacaga aagaattgaa aaaatagtca acaatttgta taatagaaac aattatttat
    22321 acaatggata cgaaaaatcg tttgaaaaag cttttaaaaa gcgaacattt ccgtaaaaaa
    22381 acgtataact gcacggattt tgggacaatt atcaaacaga tatttgtccc gattcccgtt
    22441 ttaccgaaaa aagaaagggg gatcgattcc tgtgacaaaa gaagaaattt taacgggacc
    22501 cggtgtcata aagctcgtta gtcaatacat gggtcccgaa catgtagcat ttgttgagaa
    22561 agcatgcgaa tacgcgactg ctgcacatga cggacagttt agaaaatcag gcgaacccta
    22621 cattattcat cctatccaag tcgcaggtat attagcagat ttaaaaatgg atccccatac
    22681 agtggctaca ggcttcttac atgatgttgt tgaagataca gaaatcactt tagaagatct
    22741 gagagaagaa tttggcgatg acgttgctat gttagtggac ggcgtaacca aattagggaa
    22801 aataaaatat aaatcccacg aagagcagct agcagaaaac caccgaaaga tgctgctagc
    22861 aatggctcaa gatttacgag ttatcatggt caaattagct gatagactac ataacatgcg
    22921 tacgttgaag cacctgcgag aagataagca aagaaggatc gctcaggaaa ctttagaaat
    22981 ctatgcgcct cttgcacatc gtctagggat cagccggatc aaatgggaat tagaagatac
    23041 agcacttcgt tatctaaatc caaaacagta ttaccgtatc gtccacttga tgcagacgaa
    23101 gagagaagaa cgtgaaaaat acgtaagtgg tactgttgaa gatattcgaa tagcgacaga
    23161 agagctgggg atttttgcag aaatctatgg acggccaaaa cacatttatt caatctatcg
    23221 taaaatgaaa gatcagaaaa agcagttcaa cgaaatttat gacttgctag ctattcgagt
    23281 gatcgtagat tcaatcaagg attgttatgc tgtattagga gcaatccaca caaaatggaa
    23341 accaatgccc ggcagattta aggattatat tgccatgcca aaagctaata tgtaccaatc
    23401 tttgcatact accgtgatcg gtccggcagg aaatccggta gaaattcaaa tccgaacaca
    23461 ggaaatgcat gaaatcgctg aattcggggt tgctgcacac tgggcctata aagaaggaaa
    23521 aaatgaaaaa gtagaaccag atggtatgac gaaacaatta agctggttcc atgagatact
    23581 cgaacttcaa gacgaaagct atgatgcttc tgaatttatg gaaggcgtaa aaggagatat
    23641 ctttagtgat aaagtctacg tcttcacacc aaaaggagac gttactgagt taccaaaagg
    23701 atccggacca ttggactttg catacagtat ccatacagat atcggtaaca aaaccactgg
    23761 tgcaaaagta aatggcaaaa tggtgcagct tgattacaaa ttgaaaaacg gagatatcat
    23821 tgagatcatg acttctccaa attcatttgg cccaagtcgc gactggttga aattagttgc
    23881 tactagcaaa gcaagaaata agatcaaacg tttcttcaaa gcccaagatc gagaagaaaa
    23941 tgtgatcaaa ggccacgaat ccgtggtcaa atgtattaca gatctaggat ttacgcctaa
    24001 agatattttg acgaagaaca aactgcaaga agcactcgat cgttttaatt atcaaacaga
    24061 agatgatctc tatgcagctg tagggtatgg agaagttagc cccttgacga tggccaatcg
    24121 tctgactgaa aaagaacgta aagaacaaaa aatcgagcag caaaagcaag aagcagaaga
    24181 aatcatgaat cagccgaaaa aagaacctga caaaatgaaa gtacgtcatg aaggtggcgt
    24241 tgtcattcaa ggggtagaaa acttactaat tcgtatcagt cgctgctgta atccgattcc
    24301 tggtgatgat atcgttggtt atatcactaa aggcagaggg atatccattc atcgtcgaga
    24361 ttgtccgaat gttcagcctg acaaaccaaa tgtagcagaa cgtttgattg aagtcgaatg
    24421 ggaagataca tcgaatacac gaaaagagta tgatgcagat ttggaaattt acggctataa
    24481 tcgttcaggc ttattgaatg atgtacttca aacagtcaat gcgctaacga aaaatctcaa
    24541 cagcgttgaa gcacggacga ataaagataa aatggcgacg atccatttga cggttggtat
    24601 ccagaattta tcccacctaa agagtatcgt ggataaaatc aaagcagtac ctgatgtcta
    24661 cagtgtacgc cggacgaatg gataggagga cagatatgag agcagttgtt caacgggtaa
    24721 gtaaagctgc tgtgtcagtc gatcagcaag aaattggaaa aattggctac ggcctacttg
    24781 ttttattagg cattcatgaa accgatacgc aaaaagatgt ggactatctg gtaaaaaaaa
    24841 ttgcacaaat gcgtattttt gaagatgaac aaggaaaaat gaatattagt gtagaagatg
    24901 tgggaggaca aattttaagt atctctcaat tcacactgtt tgcggatacg aaaaaaggaa
    24961 atcgaccaag ctttgtggaa gccgcacgac cagaaacagc tattccttta tacgaatcat
    25021 tcaatgaagg aatcagaagt cgcggcatca cagtcgctac cggacaattc ggagcagata
    25081 tgtcggtttc tctcgtcaat gatggacctg taacgatcat tattgattct aaaaacaaat
    25141 aaagtaatct ggttttcact agtaaaaact atgaaacacg tcgcttaagt tagactgata
    25201 aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca gcagtcggaa
    25261 aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga agatgaaaga
    25321 agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa aaggatacaa
    25381 catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa agattttcaa
    25441 taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg atccaaggaa
    25501 tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg gtcaaggtgg
    25561 agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta tggatctaat
    25621 gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga cacaagcact
    25681 tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt tctttacatc
    25741 tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg tcgaaaaatt
    25801 agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg atcacataaa
    25861 aggtgtcgaa aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg aagaagctcg
    25921 acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca atgccacaga
    25981 tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga acatcatccg
    26041 tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt tcagtagacc
    26101 agatttgtat cagcaattaa aaaatgactt ttcgacgtta caagatccgt ttattcaaga
    26161 aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga aagaagtaga
    26221 agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat atggaacaga
    26281 ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt atgtagggaa
    26341 agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg ggggaaattt
    26401 tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac gtgtgttttc
    26461 cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga cgattccatt
    26521 caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt agattagcat
    26581 aaacttatcg aaaaaaagga agatcaaaca gtgctgatct tccttttttc atattactat
    26641 aaattgataa ggtcaattga tcaaaatcca cgaaatgctt catcaatggt ttgataatct
    26701 tcattggata aatgcaaatc taaagcttgg acattgtcag atacttgctc tggacgctta
    26761 gctccaggta taactacaga cactcgtgga ttcttcatgt accaagctaa aacaagttgc
    26821 gcaggagtgg cttggtatct tttagcaatg gggcgaagta catcgacagc ggttaaaatt
    26881 tctctgaaac gttctccttg gaaatctgga tttctttttc gaggatctcc ttcaccaaat
    26941 tgtttttcct caccaagttc atattttcct gtcagcaaac cggaagcaag aggaaaatag
    27001 ggaacaaaac tgattttgtt tttttcaaga taagggaata attctttttc agcctgccga
    27061 tggatcaaac tgtatttatc ttctactaca tcgacatatc catctgcatt cgcttctttc
    27121 aattgttcta acgtgaagtt tgacacaccg actgctcgga tttttcctgc ttcttttaat
    27181 tcgtgcaatg tagcaactga ttcatttttt ggtgtgcttt catccggaaa gtggatataa
    27241 aaaatgtcga tgtaatcagt ttgcagacgt tttagtgcat cttccaccga ttgtttgaga
    27301 aactcaggag aattatcaaa tgttcgccct ttatttggta catgagcagc ttttgtagcg
    27361 atgacgacac gtgagcgatc atattctttt tccttcagta cctcgccaat cagttcttcg
    27421 gaacggccgt ttccgtaagc ataagcggta tcgatcaaat tgatcccgct attcaaagct
    27481 gtacgaacta cttgttttcc tgtctcatct tccaaaccgt caaaaagatt atgtcctcca
    27541 acggcatttg ctcctaatcc aagctgttct gcgtagactt gtgaatgtcc gattcttatt
    27601 tctgccatag ctgattcctc ctttttgtct agtctaaaac aaaataccaa aaagctgaac
    27661 taaaacgttt ttgtgagggg aaatagtcag atatctcttg actttgagac tggtttttag
    27721 taggttataa gtaatatcga atgtcaatga aagagcgagt aagtttttga aactttacaa
    27781 gagaggatca tcgaggctga aaatgatcta aagtttcatt agcctaaaga cactctggag
    27841 atggacgagt gaaaagccgt cccgcgtacg agcgttattc gtaagaggaa agagaaatct
    27901 ttcaaaatta ggtggtaccg tgtatgaatt tcattcaccc ttgttcatga tgaacaaggg
    27961 tgattttttt atttacatag ctaagaaagg gagagaaaac tatgagtttc caaagaccaa
    28021 aaggaacaaa tgatattttg ccaggcgaat cagaaaaatg gcagtttgtc gaagaaacag
    28081 cacgtttatt attcagagat tatcagtata atgaaatgcg tacaccgatt tttgaacact
    28141 atgaagtgat atcccgaagt gtaggggata caacggatat cgtttcaaaa gagatgtatg
    28201 atttttatga caaaggggaa cgccatgtga cgcttcgacc agaaggtaca gcaccaatcg
    28261 ttcgttcttt tgttgagcat aaattgttcg gcccagagta tgcgaaaccg ttcaaaactt
    28321 tttatatggg accaatgttt cgctacgaac gccctcaaaa aggacggtta cgtcaattcc
    28381 atcaaatcgg agtagaagca tttggatcag aaaaccctgc aactgatgtg gagagcatgg
    28441 tgatggcact tgatttcttc aaacagttgg ggatcacgca aatccggcta gtcatcaatt
    28501 cattaggtga taaagaaacg cgtcaagcct atcgtcaagc attgatcgac tatcttttac
    28561 cttttgaatc agagctgagt gaagactcta aacgccgcct tcatgaaaat ccattacgcg
    28621 tattggacag taaagacaaa cgagatcaaa aatttgtggc agaagctcca tctatcttag
    28681 attatctaag cgagcctgct caaaaacatt ttgataccgt tgtttccatg ctggatgcat
    28741 tggctgttcc ttatgaaatc gacagtaata tggttcgcgg actagattat tacacacata
    28801 cgatttttga aatcatgagt gacgcaccaa aaatgggggc acaagcaacg atttgcgcag
    28861 gcggacgtta tgacaatcta gtggaagaac taggtggtcc ttcaacacct ggcttcggat
    28921 ttgcaatggg tatcgagcga ttactcttga ctatggaggc agaggaagta gttatccctg
    28981 catttaatga gttggatgct tacgtggtcg cactcggaga cgaaacaaat atcgaagcat
    29041 tgaaagtggt ccaagcgatt cgaaactttg gtttttcagc tgaccgcgac ttcatgaacc
    29101 gtaaagcaaa agcgcaattt aagacagcag ataaagcgaa tgccaaatta gtattggtga
    29161 tcggtgaaga tgagcttgct agtcaaacga ttaatgtcaa agcaatggca agccgaaaag
    29221 aaaaaagttt tccattagaa gagatatatg aacattttga tgaagtctat gatgaaatga
    29281 ctttattcga gtaggaggaa aaaaataaat ggcacaaaga acgatctatt gcggattagt
    29341 ttccgaacaa caattagaac aaacagttac attaaaagga tgggtacaaa aaagacgaga
    29401 ccttggggga gtaatcttta tcgacctacg tgatcgtgaa ggaatcgttc aaatcgtctt
    29461 taatcctgaa atcaacaaag aagcatggga aatcgcggat aaatgtcgca gtgaatacgt
    29521 gatcgaagtg actggggaag ttagaagacg cggagaaaat gcagtaaatc ctaaaatggc
    29581 cactggtgaa ttcgaagtga ttgcaagtga aatcgtgatt ttgaatcaag caaaaacccc
    29641 gccatttcaa attgaagatg atcaagcaat cagtgacgaa atacgtttga aatatcgtta
    29701 tttggatctg cgtcgtccaa aaatgactaa aaacatcaaa ttaagaaatg cgacaacaaa
    29761 agcgattcgt cattatttag atgataatga ctttctcgat atcgaaacac cttacctagg
    29821 gaaatctaca ccagaaggcg caagagacta cctagttcct tcacgtgtcc atgctggaca
    29881 tttctatgcg ttgccgcaat ctcctcaatt gtttaaacaa ttgctgatga atgctggatt
    29941 cgaccgttat tatcaaatcg ttcgttgttt ccgcgatgaa gatttacgtg gagaccgtca
    30001 gcctgaattt acgcaagtag atattgaaac aacgttctta acagcagaag aaatccaaac
    30061 ttacacagag ggattgattg cgaaggtaat gaaagaagtt cgcggtatcg aagtcacatt
    30121 gccatttcct cgtatgacct atgatgaagc aatggctcgc tacggcagcg acaaaccgga
    30181 tacacgtttt gatatggaat tgatcgatct aagcgataca gtcaaagaag tagaattcaa
    30241 agtcttccaa atggctcttg aaaacggcgg tgtcgtgaaa gcattgaatg ctaaaggcgc
    30301 tgcagatcgc tactcacgaa aagacatgga tcagttaggt caatatgtag gacaattcgg
    30361 agctaagggg cttgcatggc tgaaagtaga agaagacgga ttgaaaggtc caattgctaa
    30421 attcatggga gaagcaacag aagcaatcat taaagcaaca gatgcaaaac caggtgactt
    30481 gctgatgttt ggcgcagata aaagtgaaat cgtcgctgct gcattaggtg ctatccggac
    30541 acgtttagga aaagaattag gactaattga tgaatcgaaa ttcaatttct tatgggtaac
    30601 tgattggcca caatttgaat tttcagaaga agaaggtcga tatgtctctg ctcaccatcc
    30661 attcacgatg ccaaaagaag aagatatccc gttattggct gaagaccctg caaaagtcta
    30721 tgcagaagct tatgatatcg tcttgaacgg ttatgaacta ggcggaggtt ctatccgtat
    30781 tcatactcgt gagcttcaag aaaaagtact agaaactcta ggctttacaa aagaacaaat
    30841 ggaagaacaa tttggtttct tgttaacagc tttagattac ggattccctc cacatggcgg
    30901 tattgcatta ggattggacc gttttgcaat gttattagcc ggagaagata atattcgtga
    30961 agtcattgcc tttcctaaaa acggaaaagc agcagatgtg atgagtgatg caccaagtat
    31021 ggtttcgcct ttacaattgt tcgaattgaa tattgatgta acgaatatag aagaatagcc
    31081 gataaaaagg taaaaaggat ttgtcgaata cgcttctttt gacaaccttg atttaattga
    31141 aaaacacttt ataatgaagc cataacatat aaagcggggc ttttccatga aaaaaacatt
    31201 cgaaaattgg gcttatcatg attacacgac caagctttcg gtatctatcg tttatgcgtt
    31261 gatcgcatca gtcgcattga atttctttta tcagccagga catatttatt caagtggtat
    31321 tactggtcta gctcagattt tgacgacttt gtcaaaatca ctgataggat tcgaagtacc
    31381 ggtatcaaca actttgtatt tactgaatat acctttgttt gtattggcgt ggttaaaaat
    31441 cgggaagaag tttacaattt tcacttttat cacagtcact ttgacctccc tttgtatcca
    31501 tattttaccg gaaacagtcc tatctaccga tccaatcatc tgtgcgttgt ttgggggggc
    31561 tgtgatggga ctaggtattg ggctagcgtt gagaaacggc ctatcatcgg gcggtctaga
    31621 tatcgtgagt atcacgattc gtaaaaaaac aggaaagtcg attggttcta tttcgatcta
    31681 cttcaatgca ttgatcgttt ttgttgccgg aattctattt ggctggcaat atatgtttta
    31741 cagtacgttg tctattttcg tcagtggaaa agtaactgat gtcgtttata ctaaacaaaa
    31801 gaagatgcag gtaatgatcg taacgaaaca tccagaaaaa gtagtaaatg aaatccaaaa
    31861 ctgtatgcgt agagggatca cgatcatcaa tgaagcagaa ggtgcttata agcatgataa
    31921 gcagacagta ttgatgacga tcgttacacg atacgaactg cctctactta gagaagcaat
    31981 gaaagcttct gatccacaag cttttgtaag tattgcagaa aacgtccaga tacttggtcg
    32041 tttctatgag gatggcattt agatcgagtt tgacaaaaat tcatgaaata ctgctgtaga
    32101 cagacgttcg tttgtctgca gtttttttct accatagtag aatcagcaaa gaaaaactgc
    32161 ttttttattt gaaattttct taaagttgaa aaaaagcatg tttatttttt taaatttatg
    32221 ggatgataga aaaaaatagt agagaaagga cacgattcta cttgctattt tcacttaata
    32281 cccgtatatt acgaatgaaa aaagtttatg aaaagttgga atattgaatg gaaaaacaaa
    32341 aaaggttaaa aaacagccgc tacatcactg ggtttgatgg gctccgttca ttagctgtgg
    32401 tgggtgttat cttctatcac cttctgccaa ctagtatgaa aggcggctat ttgggcgttc
    32461 cgattttttt cgtcgtatct ggttatttga tcacggatct gctgcggcag gaatgggaac
    32521 aaaatggaaa aatcaatatt tggcaatttt atgtcagaag aatgaagaga ctctatccgg
    32581 cacttgtttt tatgcttgtg acagcttcgg cttatatcac tttgtttcag cgagggctgt
    32641 taaacaatct tcgaggagtt gtggtcagca gcttactgta tgtcaacaac tggtggcaaa
    32701 tcaataacgg tttatcttat ttcgatcgat ttgctaatga gtcaccgttt acgcatatct
    32761 ggtctttagc agtagaaggt caaaactatt tggtttggcc gatcttgttt gtattgttga
    32821 tggtatttgt tcgtaaaaga aaatggatct tttatactgt gttaggtaca tccttcctct
    32881 ccgccatctt gatgatgatc ttgtatacac caggaggcga tccaacccgt gtttattacg
    32941 gtaccgacac tcgtctgttt tctatatggt tgggaagtgc gcttgcgttt gtttggccaa
    33001 gtacgcgttt aaagaaaaac atcccgaaac aagcgaaaaa tattctgaat atcgctggag
    33061 gaatctcgct tttggcactg attctttgct tcttcttttt agatgatcat tacaatttca
    33121 tctattacgg aggaatgctc ctagtgagtc tgttatgcgt agtgctagtt gcagtgacag
    33181 cacaccccgg agcaagtttg aatcgatggc tgacaaatcc agtatttact tggattggca
    33241 aacgaagcta tggcatttat ctgtatcagt ttccagttat gattttttat gaagcaaagg
    33301 tgactgatat tgccgatcat gttttgttgc atactttagt ggaaatcaca ttgattctaa
    33361 tcatcagtga actttcttat cgatatgtgg agcgtccgct agcacgtttt gattatggtc
    33421 gtacattcca agtgatgaaa ggatggttca gcaaaccgat catcagtaag agcaaaccat
    33481 gggttgttcc aggcacatta cttgtagcaa ttgcactcgt tggtttcgtt acggcaccga
    33541 aaaacgctgt aacagccgat caaaaacaac tgcaggcaaa aatcgctgaa agtaaaaaat
    33601 tagcagaaga aaccagaaac aattcagaaa acaccactag ttcggttgac caagcgatcc
    33661 ttgataagta cgagttgtcc aaggcacaag ggaataaggc acaaaaatta gaactaacgg
    33721 catttggtga ttcagttatg ttggatgctg caacggatct acaagaactt tatccaaaag
    33781 tagtggtaga tggagatgtc ggacgacaat tatatgccag tgtaccgtac attgaaaaat
    33841 taaaggaaca agatttgttg aaagacactg ttctgatcgg actaggaacg aatggctcat
    33901 tctcggaagc tcagtttgat agtgtgatgg atgcaatcgg tgatcgaaaa gtatactggg
    33961 tcaatgtccg agtaccgacg aagcgctggc aaaatgacgt gaatgcgatg cttgaacaga
    34021 tgacgaaaaa atacgacaat atgacgctga ttgattggta cagctacagt aatgaccata
    34081 gtgactggtt ttatgatgat caagtccatc caaatcctga agggatgaca cattacattc
    34141 acttagtcag cgaagccttg ctaggaggaa gttcaagtac gaacagcagt gagacaaacg
    34201 tgacagaatg atagctacaa aaaacttcag gcaaaaacat ttgtttttgc ctgaagtttt
    34261 tttatattta ccgtgttttt aacattcata tagattcagg aagcaaaacg gttgagtgtg
    34321 tctgtaaata acgttctttt tgttttcggg tgagtttttt gaatgcagct tctgcttttg
    34381 ttgcttcgct tcttgaagaa aatacttctg catggatcat cttaacaggt cttctttttt
    34441 gaagacgagt atatttagca ccagtaccat tgttatgttc ctctaatcgt ctagaaagat
    34501 cggttgtata tccaccataa aatgtctgat ctttacagaa taatacgtaa aaataatgtt
    34561 catttgccat agagcatctc acgaatctct gcagtgtatt ctccatccat attgtaagtg
    34621 atcaatggtg gagcgacttt gaatccgtct aatttgcctt ctttgattcc ttcaactaac
    34681 aaaatatttg cctcttttcc aggttttggg taaacaaatt ggatcctttt aggtgcaatt
    34741 cgatagtctt ccatgacctg aatgatttct aagaaccgat caggacgatg gaccatagta
    34801 aagcgtccat ttgtttttag tagcttactt gaaatatcga tcacttcttc taacgtcgta
    34861 tgaatctcat gacgggcgat tgccaggtgt ttattagggt tcgttttatt tgttggcagc
    34921 cctttgaaat aaggtggatt acagacgact aagtcacaag aattatgtcg aacgacagat
    34981 aagctgtctt tcagatcgat ggtgtggaca gtcatttgtt catttaaatg gttaagcgcg
    35041 atactacgtc ttgccatgtc tgctagacga ggttgaagtt cgatagcgtc gatagccgcc
    35101 tgggttcgtt tacttaaaaa aagtccaact gcgccatttc ctgcacaaag gtcaacaatc
    35161 ttcccttttt taggtacacg ggaaaagtga gcaagcagca cagcatctaa agaaaaagaa
    35221 aacactttgg aactttggat aatcttgata tcttctgcgt ataattggtc gattcgttcg
    35281 tcttcgtgaa gcatggattc cctccaaaat gaaaaaaata gtcgtctgta ttatactatt
    35341 tttattaaaa agaaccaagg tggcttgtca aacctctatt ttttatgcat actatgacca
    35401 taagaaggga aaggaagaga ctatgtttta tcgatttatg cgcggggtag ttcgagtact
    35461 attagcctta gttaatggaa atgcccgcta tgagaataaa gaagttttac cgcaagatga
    35521 gaattacata ctagttgctc cccatcgtac ttggtgggac ccattatatc tggcggtagc
    35581 tgcagcaccc aaggaattca gctttatggc aaaagaagaa ctgttcaaaa atccagttct
    35641 gcgatttata ttaactcgat ccaatgcttt tccagttaaa agagaaaatc caggaccaag
    35701 cgtcattaaa acacctgtaa agattttgaa atcgacaaat ttgagtttga tcatgtttcc
    35761 cagtgggaca agacatgcta cagaacttaa aggcggaatg gcattgattt ccagaatgtc
    35821 taaagcgaaa atcgtgccag ctgtatatca aggtccgttg acacttgggg atctgttcaa
    35881 gcgtcagaga gtgacagtgc gtttcggcga accaatcgac ttatcagata tcaagaaaac
    35941 ggataaagaa ggtatggcgg agatcgaacg acgaacacaa gcagcttttg acaaattgga
    36001 caaagaagtg aaccctgatt tcaaatatga agtcaaaaaa aaataaaatg ataagtttat
    36061 gcgtgggcgg tcttttgaat ctactgtcct gttcagttca gactttttca atgaaaacga
    36121 gggagagacg tcaagtctgc cctctttttg cgttccaata tgtaaaatag aagacaggtg
    36181 tcatgtaatg gatcaaagtg ttataataat tagaaggaca ttttttgagg tgattgaatg
    36241 cgttttttac atacagccga ttggcatatc ggaaaaaaac tacaaggtta tgacttgatt
    36301 gaagaccagc gtcatgtact atcttctata ctagatatcg cgaaagaaga aaaagtagag
    36361 gcaatcgtga ttgccggaga cttatatgat aggagtgtcc cagctgttga tgccgtagaa
    36421 ttatacaatg aattgatggt cgattggaat ttaaaggaaa agatcccgat ttttgctata
    36481 tcaggaaatc acgatagcag tacgagactt tcagcgggta cgccatggtt cagttattcg
    36541 aactattttt tgcgaacaca gctagcagaa gcatttgaac cagtcgagtt taaaaacgta
    36601 caatttttct ttcttcctta ctttgaacca attgcagcga gattatattt tgaagatgac
    36661 aatatccgaa cgatcaagca agcggtagcc aaggtgatag ataaaatgca ggagctattt
    36721 gattcagaaa aaaaacaagt attgattagc catttttttg taatgggaag tgtaaaatct
    36781 gattcggaaa cgaaaatcga agtaggcggg ttggattcga tccctggtga actacttaca
    36841 ccgtttgatt atgtagcact aggacatttg cataatcaag ctgctttgag acaggataat
    36901 gctcgctata gcggttcccc attgaaattc tctttatctg agatcaacca aaaaaaaggc
    36961 gtatggatcg ttgacctgac aacaggcctg gagttgaatt ttagggagat cgaacccctg
    37021 catgatattg aagaaataac agcgagtttc aaagaattgc tggatcctgc cttttatcag
    37081 tccgtcaatc gggagaatta catctatatc tatctcactg atagaacgat catcccgaat
    37141 atgatgaacc agcttcggca aatatatcct cgtattttgg ggattgaacg ggcaaacggt
    37201 cgagcagaac aaacaaagcg caaacgaaaa gtactagaaa tgaaagatcc tcaaaaatta
    37261 gcagaagcat tttttagtga aatgacggaa gagcagctaa ctgcaaacca agaaaaatgg
    37321 ctcggagaaa cgttgcaaga aatcatggaa atggaatgat caagaatgaa accgaaaaaa
    37381 ttacaactta aaaattttgg tccttttatc aatgagaccg tagatttttc acgtttgaca
    37441 gaagcaccgc tttttttgat cagcgggaag acaggagctg gcaaaacgac gatttttgat
    37501 gggatcacct tcgcactttt tggtgaaact tccggaagac ttcgctctgg aaaagagatg
    37561 cgttctttgt ttgctacacc agacgaagaa acaagcgtga ctttttcttt tgaacatcag
    37621 cagatgagct atgaaatcga acgaaaacca gaacaagttt tagcaaaacg aaaaggaaac
    37681 ggaacaaaaa aacaggcagc caaagtaacg ttgaccattt ttgatgggaa aggaaaagaa
    37741 ataaaacaaa tcacaaaacg tacagaagca gatcagttga tcagagaact gatgaatctc
    37801 gatgcgaaac agttttctca aatcgtttta ctaccccaag gagaattccg taattttttg
    37861 gtttcatcaa gcagtgataa agagactgtt ttacgtcatt tattcggtac tcaatttttc
    37921 caacagttca atgagcgatt aaaagaaaaa gcaaaacaac agcaacaaaa attggatcat
    37981 ttagagcaag agctgcatct tctgcaaaaa aggtttgttt tagtcaaaga agaggaacca
    38041 gcagcagggt ttgaagccgt tttagcccaa tggacaaacc atcaggcaat actcgaaaaa
    38101 caaatcacgg aagaaaaaga agctctaacg gaacttcagg aaaaacaaaa gcaactagaa
    38161 aattcctact atcgttttga aagcttgaaa aaaagttatg aagaaaaaac gatattaata
    38221 aacaagcaaa aggaattagc tgctcaaaaa gacgaaatag aggaaaagaa acgatggatt
    38281 gggtattatg aatttacgca acgattagtc gaaccaatcc agcgcctaca agaaataaaa
    38341 gttgaaaaaa tagaactgtc acaaaaaagt agtgagcaaa caaagaaact agcgatgact
    38401 acgcagaatt atgaagagtg gcaaaaaaat gaagcaaacc gcgtacgccg acaaacaaaa
    38461 atcaaagaag ctgctcaaaa actgcaaaac aaacagatga tggtgccaat tgtcgaatcc
    38521 ttacgtagta aaaaacaaga cgcagaacaa ttaacaattt cattggataa agaagaattg
    38581 aatgccgaga agctgtatca aaatctcgct atctatcagg aaagaactcg aattcttcaa
    38641 gaaaatttac tggatcagga aaaactgcaa gaagatcgtc ttgcttttgg acagttaaaa
    38701 tatctagatg aaaagcagca agaaatagaa aaacaaaaag caaaagacac tgggtcgctc
    38761 gcacagataa gagaagaact caaaaaagca actgaagaaa taacaaaaaa tagtcagcta
    38821 ttgaaagaac agacagaaca agcagaacag ctgaaaagcc aatgggcaaa gcagcaaatt
    38881 gctcgtcttc agcttttttt gcgtccaggg gagccatgtc ttgtttgtgg atcaacggaa
    38941 caccccatac aacaattaaa acacgaacag ccaaataagg aagatatctt aaaagtagaa
    39001 caacaactgg cagaagctga gtctgctgta gaaagaactc agcaaatcat tgccaaaagt
    39061 gaagcacatg aaaataatct tcaacaacaa ttatcagatt tagaacaaaa aatcatggca
    39121 acgaatatac aattggctga acaagaagaa cacttgcaac aggctttgaa aaaggcattt
    39181 cctgagataa cagaacaaaa aacaaaaaca actcttgtag taatcgaaca atctttagat
    39241 agacgaaaaa gcaagatggc caatgcaaga atagagctgg aagaaataag acaacaagca
    39301 gaaaagctcg aacaacaatt agctgtctac aaacagcagc agacagaaaa aaataatcag
    39361 ctccagcaac tgcaaggaga aatcaaaagt ttagaacaac aattgcaaga tacggatagt
    39421 aactgtttag aagaggagat acgacgactt gaaaaacagt tagaagaaga ctcgaatcaa
    39481 ctagctgttg agcagaaagc aggagtgcaa ttgttgcaag atcttcatac gcttcggaca
    39541 cagcttgatc ttcaacatga acaaatagaa aaaatagatg aaaaaataga aaaggaacaa
    39601 gaaagaatag ctaaaaagtt agaaagccag tcgtattttt caacaattga agaaatctgt
    39661 gcatttgcac aacagcaagc acaatataaa gaaaaccaac gtacagttac ttcttatcat
    39721 gaagagcaat tagtgacagc tgaccggctg cgtcaattag aaaatatcca gctaactgag
    39781 acattcccag atacagaaga gatcagccaa cagttagaag aaataagacg tatgatcgaa
    39841 ataaagcaag aaaagatata cggtttacaa gaacaaaaaa ttagtaatca aaaaatctac
    39901 gatgaatgtc tttcgattta tcacacaagc cagacgaaat tagatgagct tacgcaatta
    39961 cagcagcttt cgcaaacatt caacggagaa aatcctaaga agactagttt ggaacggtat
    40021 gtgcttcagg tttatcttca agaagtgtta caagtagcaa atgatcatct ccaacgttta
    40081 acgaaaaatc gttatcaatt tgagctagcg gataccattg gcagttatcg agggaaaacc
    40141 ggattagaaa tcaatatcta tgatgatcag gcaggtatgt ctcgaagtgc gcataccctg
    40201 tctggcggtg agagttttat tgcagcactt tctttagcat tagctcttgc cgatgtgatc
    40261 cagacacaag ctggtggtgt agcaatcgat gcattgttta ttgatgaagg atttgggtca
    40321 ttagatgaag aagctttgga aatggcaatg gaagctttag aaacgatcga aagtgaagga
    40381 agaatgatcg gcatcattag tcatgtaaga gaattgaaag aacgagtatt acaacaaata
    40441 agaattgata cagaaggtag cggacaaagc aaaatacgct atcaacttgg ataaaaaggg
    40501 agattggtaa ctatgaaatg gagtattcca gaaaaagtca ttgcacgtgg acgtcaatac
    40561 ttgcaagaag gccgagtgtt atcggttgtc cctgaccaag aagaaaacgt gtggcatgca
    40621 gaagtcttgg gcagtgaatt gtatatggtt gatttggatg gtacagcaaa agagatagat
    40681 tactgccaat gtccctattg ggaggaacat aaatattgta agcatacagt tgctgtggaa
    40741 ctttatttac ggtcgaaaaa tctatctcgt atcatgaaaa aagaccagcc aatgctagaa
    40801 ccggtaaaag caacaagtga gggagaaatc attgcaaaag gtttttctcg tctaaaaaca
    40861 caaaacaatc ctcaagcggt gcaacctttg attattgaat accaagtaga aacgattgag
    40921 actaatcagt atcacccaga gctttctatt ttggcacttt acttgcgtat cggttcattg
    40981 gcatcaccga aaaaaacata tatcgtaaaa aacatctatg attttttaca agcttacaca
    41041 gaaaaagaaa cttacactgt taataaacag taccagtttc gtctagataa acgggcgttt
    41101 caaaaagaag atcaaaaaat actcacgcat cttgcaggaa gtgctcagac gcatcaatta
    41161 ttaggtacga acggcttaca agtcaaagga aaactagata aaagatatct gcttctccca
    41221 gtagaacaag cccgcttcct gttagagcag atgaatcaga ctacacgttt gcatctgcag
    41281 ataaatgaac aaaacgatca aggaatacaa ttttccgatc aaaacaaacc tttatcattc
    41341 aaagtggaaa aatttggaga agattatttg ctgcaagcat tgaatgattt tgattttttc
    41401 tttatgcatt atcagtgggg agttatccaa gggacatttt attctctgac gaaatatcaa
    41461 caaacggttt atcaaacttg gaaacaattg attcgccgat tggagaaacc agaagtagtg
    41521 ttcaagaaaa aagaattacc gtctttgttt aaagagatta tccctctgct gtcagagatc
    41581 ggcgacgtag ctattgcccc tgcagtagaa gaggaagtag cagatatccc cgtcgaattt
    41641 attttctttt tccgaaaagc aaaaggaaaa atccaagctc gagtcgattt cgtctatggc
    41701 gaagtcatct attcgactga cccgaagcat gaggtctcga cagaacaggc ttttcaggtg
    41761 ttacgtgaca cagtagaaga gaaacgagta cttgatctat tcagaatgta tcgctaccag
    41821 aaaaatgaaa ctggttatga acgtccattg ccaagcgggg aagaactata tgcctttttc
    41881 cgcacagaac tatctgtctt ccgtcagttt ggtgaagtca gacttggaag aaaattgcga
    41941 gagttgtatt tagatgcgca taaacatcaa ccgaaaatcg aagtaaccga gaccggttca
    42001 tggctcgata ttcgattcga tgtgacaggg atagaggagc aagaaatcga tcatgtcctg
    42061 caaagcttgc tgagaaatga tgctttttat acattagaaa atggtcaggt tctttctttt
    42121 gattcagaag aatttcaaca aacaagccaa gtgttgcaac aattacggga atcgatacgt
    42181 acagaagaag gaacgatcca tgtacctaaa aatcaaggat tgatcattca aaatcaattg
    42241 gaaaaaagca atgctacttt tagtgaatcg ttccaaacga tggtacaaga tctcattcat
    42301 ccagaaagat accaggcaca gcttcccaaa ggattgaatg caacgatgag agattatcaa
    42361 aagcaaggtt ttcgatggtt gaagatgtta ggtcattatc agtttggcgg tattttagcc
    42421 gatgaaatgg gacttgggaa aacactacag acaattgcct ttttactttc ggaaaaagaa
    42481 gaacggaaaa gcttctctgc tttgatcgta gcgcctgcga gcttaattta caactggcag
    42541 gcagaggtga gaaaattcgc cccttcttta agtatccaag taatcaatgg gaataaaaaa
    42601 gaacgtgaag aattactggc taaagacaca gatatccgag tgacttctta tgccagctta
    42661 agacaggatc tagctaatta tcagtcgcaa aaaattgatt atttgattct tgatgaggca
    42721 caaatggtca aaaatagcag tacgaaaact gcacaagcat tgagagaatt agctgtacct
    42781 cagcggtttg cactgagtgg gacaccaatc gagaataatt tagaagaatt gtggtcattg
    42841 tttgcaacga ttatgccagg atttttcccg actaaaacaa aattcaggga acttgccgca
    42901 gaagaaattg cgcaaatgat tcgaccgttt attttacggc gagataaaca aactgtgttg
    42961 aaagacttgc cggaaaaaac agagatgaat ctatattctg cacttacaga agaacaaaaa
    43021 actgtttatt tagcttactt gcgtcaaatg cgtgaagaaa tcacatcaat ggattctgaa
    43081 gcattcaaga aaaaccggat cgggatactt gctggtctga caagactgcg acaaatttgc
    43141 tgcgatcctc gtctgtttat tgaagattac caaggcggtt ccggcaagct cgaacaagta
    43201 aaagatctac tggtagctgc caaagagaac aaacgaagag ttttgctgtt ttctcaattt
    43261 acagggatgc tgactatctt gcaagaagag ttagccgagc tagggatctc gacattttat
    43321 ttaagaggca gtacgaaacc acaagatcgg ttaagtatgg tagacgcatt taatgctggc
    43381 gaaaaagatg tttttctgat ttccttaaag gctgggggaa ctggattgaa tctcacggga
    43441 gcagatacgg tcatcttgta tgacctttgg tggaatcctg ccattgaaga acaagctgct
    43501 ggacgtgcac atcggatcgg acaaaaaaat gtggtagaag tgtggcgtat gatctctgaa
    43561 ggaacgattg aggaacgcat ggattcactc cagcaagaaa aacgcgaact gttccaaaaa
    43621 gtgatccaag gtaatgaaga acagttgacg aaactgactg aagaagacat ccgcatgatt
    43681 ttaagtgtag gagaaatcga ggagtaagag actcgaaaaa gcgttcagta atgggtaaga
    43741 aagcctttct aaagaagcga ttgtttattt gatttaaaaa atagcaagga ggctgggatt
    43801 ccattttatc ccagcttcct tgctatcatt tttttatttc tatttttaaa ggttatacaa
    43861 agattgtctt cattgtctct aacagctgat caaaagaaga aatctcgata tcgcaaattg
    43921 gagtctgttc aattttgcgt tctcgatggt tgaaccaaag cgcttgccag ttagcacttt
    43981 ttgcacctag aacatcattg tcgtaattat cgccaacgta taaggtctct tctggaagca
    44041 tatgaaattc tttctcagct agctgaaaaa tctctttttc tggtttttgg aaacctgttg
    44101 cttgagaaat gagcatattg cgggaaggaa tccaattgtt caattgaagt tgcttcagtt
    44161 tttttgtctg atggtcagtc ggcccatttg tgataattcc taatgggaca ttcttttcct
    44221 tcaagaaatc gagggttttt ttgacctcct catgcaagca gatattatca agttcttcct
    44281 cgtaaatttt ttgaaataag aggccatctt cttccgtaat atgagggtag tctaaatctt
    44341 ttagtgattg gctgatccga tgtgctcgca tatattctag tgtccaatct cctgccatta
    44401 cttttgggaa gttttcatca ctatgatggc ggaaccggat atatagtgga tgcatatctg
    44461 catctgaaac aagcggaacg actcttttga ccgcgtttcg aaatggctgc tgctgatcat
    44521 acatcgtatc atcaacatca aacacaactg atttaatcaa aattttacac gcctttcggt
    44581 tttcattgat tttttcacaa atccttgact attgtaacag aaaaaattgt ctaaaaaagc
    44641 tgataaataa aggtttttct tactatattt ctatttcctt gacagaataa ggtttttata
    44701 tttcagtttt tttcactaaa aatcgtgaaa cacgtcaata agtttgatga acaaattaat
    44761 cattatggta gaagtcgatt gatttatttt aatgcaatct ctgtggaatt ttcgaaagat
    44821 ttattttttt
//
LOCUS       DACCVZ010000015        44700 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.015, whole genome shotgun sequence.
ACCESSION   DACCVZ010000015 DACCVZ010000000
VERSION     DACCVZ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.015"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            42..2639
                     /gene="adhE"
                     /locus_tag="IVW63_000794"
                     /gene_synonym="adhC"
     CDS             42..2639
                     /gene="adhE"
                     /locus_tag="IVW63_000794"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAP7859091.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            2868..3974
                     /locus_tag="IVW63_000795"
     CDS             2868..3974
                     /locus_tag="IVW63_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAP7859092.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            3991..5019
                     /locus_tag="IVW63_000796"
     CDS             3991..5019
                     /locus_tag="IVW63_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HAP7859093.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            5025..5504
                     /locus_tag="IVW63_000797"
     CDS             5025..5504
                     /locus_tag="IVW63_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HAP7859094.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            5520..6815
                     /locus_tag="IVW63_000798"
     CDS             5520..6815
                     /locus_tag="IVW63_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HAP7859095.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            6826..7650
                     /locus_tag="IVW63_000799"
     CDS             6826..7650
                     /locus_tag="IVW63_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP7859096.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            7815..8714
                     /locus_tag="IVW63_000800"
     CDS             7815..8714
                     /locus_tag="IVW63_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP7859097.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(8840..9709)
                     /locus_tag="IVW63_000801"
     CDS             complement(8840..9709)
                     /locus_tag="IVW63_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP7859098.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            9862..11322
                     /gene="rhaB"
                     /locus_tag="IVW63_000802"
     CDS             9862..11322
                     /gene="rhaB"
                     /locus_tag="IVW63_000802"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HAP7859099.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            11319..12575
                     /gene="rhaA"
                     /locus_tag="IVW63_000803"
     CDS             11319..12575
                     /gene="rhaA"
                     /locus_tag="IVW63_000803"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HAP7859100.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            12589..13434
                     /gene="rhaD"
                     /locus_tag="IVW63_000804"
     CDS             12589..13434
                     /gene="rhaD"
                     /locus_tag="IVW63_000804"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HAP7859101.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            13436..13747
                     /gene="rhaM"
                     /locus_tag="IVW63_000805"
     CDS             13436..13747
                     /gene="rhaM"
                     /locus_tag="IVW63_000805"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HAP7859102.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            13829..14980
                     /gene="fucO"
                     /locus_tag="IVW63_000806"
     CDS             13829..14980
                     /gene="fucO"
                     /locus_tag="IVW63_000806"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HAP7859103.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            15107..15865
                     /locus_tag="IVW63_000807"
     CDS             15107..15865
                     /locus_tag="IVW63_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAP7859104.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            15965..16609
                     /locus_tag="IVW63_000808"
     CDS             15965..16609
                     /locus_tag="IVW63_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAP7859105.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            16616..17623
                     /locus_tag="IVW63_000809"
     CDS             16616..17623
                     /locus_tag="IVW63_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAP7859106.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            17639..18481
                     /gene="kduI"
                     /locus_tag="IVW63_000810"
     CDS             17639..18481
                     /gene="kduI"
                     /locus_tag="IVW63_000810"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HAP7859107.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            18501..19304
                     /locus_tag="IVW63_000811"
     CDS             18501..19304
                     /locus_tag="IVW63_000811"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HAP7859108.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(19553..20617)
                     /locus_tag="IVW63_000812"
     CDS             complement(19553..20617)
                     /locus_tag="IVW63_000812"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAP7859109.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(20614..21699)
                     /locus_tag="IVW63_000813"
     CDS             complement(20614..21699)
                     /locus_tag="IVW63_000813"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HAP7859110.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(21712..22689)
                     /gene="mvaD"
                     /locus_tag="IVW63_000814"
     CDS             complement(21712..22689)
                     /gene="mvaD"
                     /locus_tag="IVW63_000814"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HAP7859111.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(22682..23626)
                     /gene="mvk"
                     /locus_tag="IVW63_000815"
     CDS             complement(22682..23626)
                     /gene="mvk"
                     /locus_tag="IVW63_000815"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HAP7859112.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            23948..24601
                     /locus_tag="IVW63_000816"
     CDS             23948..24601
                     /locus_tag="IVW63_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP7859113.1"
                     /translation="MIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFYAN
                     PEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEVRV
                     YDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYDYY
                     KELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVAI"
     gene            24686..25591
                     /locus_tag="IVW63_000817"
     CDS             24686..25591
                     /locus_tag="IVW63_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP7859114.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(25593..26225)
                     /locus_tag="IVW63_000818"
     CDS             complement(25593..26225)
                     /locus_tag="IVW63_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAP7859115.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            26545..27069
                     /gene="infC"
                     /locus_tag="IVW63_000819"
     CDS             26545..27069
                     /gene="infC"
                     /locus_tag="IVW63_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAP7859116.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            27141..27341
                     /gene="rpmI"
                     /locus_tag="IVW63_000820"
     CDS             27141..27341
                     /gene="rpmI"
                     /locus_tag="IVW63_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAP7859117.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            27394..27753
                     /gene="rplT"
                     /locus_tag="IVW63_000821"
     CDS             27394..27753
                     /gene="rplT"
                     /locus_tag="IVW63_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAP7859118.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            28005..29342
                     /locus_tag="IVW63_000822"
     CDS             28005..29342
                     /locus_tag="IVW63_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAP7859119.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            29390..31519
                     /locus_tag="IVW63_000823"
     CDS             29390..31519
                     /locus_tag="IVW63_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAP7859120.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            31494..32183
                     /locus_tag="IVW63_000824"
     CDS             31494..32183
                     /locus_tag="IVW63_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859121.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(32591..33204)
                     /locus_tag="IVW63_000825"
                     /pseudo
     CDS             complement(32591..33204)
                     /locus_tag="IVW63_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(33340..33534)
                     /locus_tag="IVW63_000826"
     CDS             complement(33340..33534)
                     /locus_tag="IVW63_000826"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859122.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(33584..34024)
                     /locus_tag="IVW63_000827"
     CDS             complement(33584..34024)
                     /locus_tag="IVW63_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAP7859123.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(34028..34873)
                     /locus_tag="IVW63_000828"
     CDS             complement(34028..34873)
                     /locus_tag="IVW63_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HAP7859124.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            35022..36440
                     /gene="pepV"
                     /locus_tag="IVW63_000829"
     CDS             35022..36440
                     /gene="pepV"
                     /locus_tag="IVW63_000829"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAP7859125.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(36497..37444)
                     /locus_tag="IVW63_000830"
     CDS             complement(36497..37444)
                     /locus_tag="IVW63_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP7859126.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(37667..38017)
                     /locus_tag="IVW63_000831"
     CDS             complement(37667..38017)
                     /locus_tag="IVW63_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP7859127.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            38217..39296
                     /gene="pepA"
                     /locus_tag="IVW63_000832"
     CDS             38217..39296
                     /gene="pepA"
                     /locus_tag="IVW63_000832"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HAP7859128.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            39440..39760
                     /locus_tag="IVW63_000833"
     CDS             39440..39760
                     /locus_tag="IVW63_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAP7859129.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            39782..40246
                     /locus_tag="IVW63_000834"
     CDS             39782..40246
                     /locus_tag="IVW63_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP7859130.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            40451..41056
                     /locus_tag="IVW63_000835"
     CDS             40451..41056
                     /locus_tag="IVW63_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HAP7859131.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(41095..42384)
                     /locus_tag="IVW63_000836"
     CDS             complement(41095..42384)
                     /locus_tag="IVW63_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAP7859132.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            42812..43291
                     /gene="rlmH"
                     /locus_tag="IVW63_000837"
     CDS             42812..43291
                     /gene="rlmH"
                     /locus_tag="IVW63_000837"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAP7859133.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            43376..43885
                     /locus_tag="IVW63_000838"
     CDS             43376..43885
                     /locus_tag="IVW63_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HAP7859134.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            43985..44635
                     /locus_tag="IVW63_000839"
     CDS             43985..44635
                     /locus_tag="IVW63_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859135.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
BASE COUNT        14214 a         8088 c         9584 g        12814 t
ORIGIN      
        1 aattatttaa caaataacca tgacccatta ggaggataat gatggctaaa gtaatagaaa
       61 aagaaaaaac gaagacaatt gacgtacaag caatgattga tgatttggca gaaaaagcaa
      121 atgcagcatt gaaagaaatg gaaagctttg atcaagaaaa agtagaccat atcgtgcatg
      181 aaatggcaat ggcagctttg gatcaacata tgccattagc gaagatggct gtagaggaaa
      241 caggccgcgg tgtttacgaa gataaagcaa tcaaaaatat gtatgcgtcc gaatatattt
      301 ggcataatat caaacatgat aaaacagttg gtgtgatcaa tgaagatgtc caaaaagggt
      361 tgattgaaat tgctgaacca gtcggtgtgg tttgcggagt aactccaaca acgaatccga
      421 cttccacaac gattttcaaa tcaatgatcg cgttgaaaac aagaaatcca atcgtttttg
      481 ctttccatcc aagtgcccaa aaatcttctg cagaagcagc acgagtggta cgtgatgctg
      541 ctatcgctgc cggagctcct gaaaattgta tccaatggat cgaacatcct tcgatcgaag
      601 cgacttctat gctaatgaac catccaggta tcgcgatcgt cttagcgaca ggtggagctg
      661 gaatggtcaa gtctgcttac tctacaggaa aaccagcttt aggtgtaggt ccaggtaacg
      721 taccagctta tattgaaaaa acagcaaaaa ttaaacgtgc agtgaacgat ttgatcgttt
      781 cgaaaacatt tgataatgga atgatttgtg cttctgaaca agctgtgatc gtggataaag
      841 aaatctatgc agcagtaaaa gcagaattcc aagcacacca agtttatatc gtaaaaccag
      901 atgaattgca aaaattagaa gatgcagtga tgaacgaagg aaaatatgcg gtcaatccat
      961 caatcgttgg acattctgcg atggaaatcg caaaattggc aggaatcagt gtaccaaaag
     1021 gaacgaaaat gctgattgct gaattggaag gcgtaggccc agattatccg ctatcaagag
     1081 aaaaactttc tccagttctt gccatgatca aagctaacaa cacggaccat gcgtttgatt
     1141 tgtgtgaagg tatgttgaat cttggaggat taggacatac agcagttatc cattcagaaa
     1201 acgaagagtt gcatgtcaaa ttcggtcttc gaatgaaagc ttgtcgtatt ttagtgaata
     1261 caccatctgc agaaggcggc atcggtgata tctataacga aatgattccg tcattgactt
     1321 tgggatgcgg ttcttatggt aagaactctg tttctcgtaa cgtctctgct gtaaacttaa
     1381 tcaatgtcaa aactgtagcg aaacggagaa ataacatgca atggttcaaa ttaccgccaa
     1441 aaatcttctt tgaaaagaac tctctattgt acttagagaa aatggaaaac gttgaacgtg
     1501 tcatgatcgt ttgtgaccct ggtatggtcc aattcggtta ctgcgataca gttcgtgaag
     1561 tattggcacg acgtaaaaat gatgtgaaga tcgaagtctt ctcagatgtt gaaccgaacc
     1621 catcgacaaa taccgtatac gcaggaacga aactgatggc agacttcaag ccagatacag
     1681 taatcgctct tggaggcggt tctgcaatgg acgcagctaa gggaatgtgg atgttctatg
     1741 aacacccaga cacatctttc tttggtgcaa aacaaaaatt cttggatatc cgtaaacgga
     1801 catataagat cgacaaacca gaaaaaacac aattcgtatg tatcccgaca acatcaggga
     1861 ctggttctga agtaacgcca tttgcggtca tcactgacag tgaaacacat gtgaaatatc
     1921 cgttagcaga ttatgcattg acgccagatg tcgcaatcgt cgatcctcaa ttcgtcatgt
     1981 cagttccagc atctgtcaca gcagataccg ggatggatgt gttaacacat gcaatcgaat
     2041 cctatgtttc agtcatggct tcagattata cacgtggatt gagcctacaa gcaatcaagt
     2101 tagtctttga ctatttagaa aaatcagtaa aaacacctga tatggaatca cgtgaaaaaa
     2161 tgcacaacgc ttctacaatg gctggtatgg cgtttgctaa cgcattccta ggtatttgtc
     2221 actcagtcgc acataaaatc ggcggggaat acgggatccc tcatggacgg acaaatgcga
     2281 ttcttttacc gcatattatc cgctataatg caaaagatcc acaaaaacat gcgatgttcc
     2341 ctaaatatga ctatttccgt gcagatacag attacgcaga tatcgcaaaa ttcttaggtc
     2401 tgaaaggcga aacaacagag gaattagtcg aagctttagc aacggctgtt tatgaattag
     2461 gaaaatctgt cggcatcaac atgagtctaa aagctcaagg agtcacacaa gaaacactag
     2521 atacaaccgt agaccgtatg gctgaattag cttacgaaga ccaatgtacg acagctaatc
     2581 cgaaagaacc attgatctct gaattgaaac agatcatcat tgatgcttac aacggataag
     2641 caaaagaaag cgtagaaaaa agataagaaa atagatgaaa aagaacttgg aaaacgttgt
     2701 ttctccaagt tcttttttta atttccaagt aactgaaagt tacttttgtt atttaacatt
     2761 taggtcaatt ttagacagtt tttgttcaaa aagcgatatt tatagtggac ggtattactg
     2821 ctatattaag gatataaaat gaaagcgttt aaaaaggtgg cgtaaagatg attattaaag
     2881 aagagatttt tgtacctaaa gaattagtga aagaaaaaat tgacctgctc gttgaaaacc
     2941 tgacaacgat caaagacgat aatggtgaat ttttgttgga ctttgatgga ctgaaagtag
     3001 atgacaaaag ctggacagtg tggaattggc cacaaggtgt cggtctatat ggtatttata
     3061 aaaattacca gatgacaaaa aatcctcgcg cttatcaagt ggtcaatgaa tggtttgagg
     3121 atcgtatgga agaaggcgct ccgcccaaaa acgtcaatac aatggcaccg ctattgacta
     3181 tggcttactt gtatgaagac acgaaagatt cacgctattt gccttattta gaacaatggg
     3241 cagaatgggt catgaatgac atgcctcgga caaatgaaga cgggttacag catgccacat
     3301 atggaccgga aaataagaat cagttgtggg acgatacatt gatgatgaca gtgcttcctt
     3361 tggcaaaaat cgggaaactg ttgaatcgcc cagaatattt agaagaagct cgttaccagt
     3421 ttatgatcca tatcaaatac ttgatggata aacgaacagg attgtggtat cacggctgga
     3481 cgtttgaagg aaatcataac tatgccgaag cattttgggc tcgtggaaac tgctggttga
     3541 cgattgctat tccagagatc attgaaatct tagaattatc gaaagaagat gcattgcgca
     3601 aattattgat cgaaacactt gaagcacaag tgcgtgcatt aaaaacttat cagtctgaaa
     3661 gcggtttatg gcatacgttg ttggatgatc cttcttctta cgtagaatct tctgcaactg
     3721 caggatttgc ttacggtatt ttgaaagcgg tccataaacg ttatttacca caagaatata
     3781 aagaagtcgc ttatcgtgct atccaaggat tgcttgaaca aatcgatgaa aaaggagaag
     3841 ttcaaaacgt ttcaatcggg acaggaatgg gggacagttt agatttttat cggaatatcg
     3901 gaatcacagc aatgccttat ggacagtcgt taacggtgct ttgtttgaca gaattgctcg
     3961 tctcttattg ttaaaagaaa ggaaacccat atgaaaaaaa catcactgct gtttgcagca
     4021 agttcgctta gcctaggtct gctaggtcta agcggctgcg gaaataattc tagtgtggca
     4081 actgtcgcag atgcagatgt aaatgagata gttaccttgc gctttgctta tgcaagcaac
     4141 agccagccag taattgatgc aatgaatgaa tttgggcgtt tagtaaaaga aaaaacagat
     4201 ggttccgtac agatccagta tttcccagat ggacaactgg gtggagaacg tgaactgatc
     4261 gaattgacac agtcaggagc agtagatttc acaaaagtaa gtgcctcagc gttggaaagt
     4321 ttctctaaag attattcgat tttttcagtt ccttatctat tcaatgatga agaacatttc
     4381 tttaaggtga tggataatga agaaataatg gagccaatct accaatcgac caaaaattta
     4441 ggatttaccg gattgaccta ttatgattct ggtcagcgca gcttttatat ggtagacggt
     4501 ccgatccata cgccggaaga tttggaggga aagaagatcc gtgtgatgca aagcgaaacc
     4561 gctatcaaaa tggtagagct tttaggcggt tcgcccgtac ctatgggaag tgatgaagtg
     4621 tacacgtctc ttcaatccaa tttgatcaac ggatcagaaa acaatgaatt tgtcttgtat
     4681 acagctggac atggtggtgt ggctaaatac tattcctatg atgagcatac acgtgtgcca
     4741 gatatcatca tcatgaatga tgccatcaaa gaacagctaa ctgatgagca ggaaaaagcc
     4801 attgaagaag cagcgaaaga atcaacggtt tttgaaattg aagcttttgc aaaagcaatt
     4861 gaagaagaaa aagctttagc acaagaagaa catggagtcc aattcaatga tgtagataat
     4921 acaccgtttc gagaggcagt tgccccactt catgatatat tcaaaaacga tcctacctac
     4981 aaagaccttt atcaaaagat ccaagagcaa ggagcgtagc tgtgatgaaa atgattttaa
     5041 acaaggtatt agagatcctg ggagctgttt tgcttgttgg gatggtcgct gttgttttat
     5101 ggcaagtatt ttccagaacg gttttaggaa atccaaatac ggtcacggaa gagcttgttc
     5161 gattcggtct tgtctggttt gccatgttgt cttccgcgta tgttgtggga caaaaagcac
     5221 atttagccgt aacggtttta agtgaaaaat taactggcaa aaaaagtaaa attttagaag
     5281 ttgttgttca aagtttattt ctggtatttg ctgcgatgat catggtgtat ggcggatgga
     5341 atgctgtcac attgacaatg gggcagatct cgccttcttt aagtattcct atgggatatg
     5401 tttatctgtc agtacctgta tcgggggtac tcatcattat ctatagcctg atcaatctaa
     5461 tcgatacatt aagcaacaag ccagcaattc aagaaaaaat ataaaaatgg aggaataaaa
     5521 tggcaataga agccggatta gtgttatttt ttgtatttgt tgtgttgctt gtattaggga
     5581 tgccgattgc tataagtatt gcattctcat cgatgatgac tttattgtta gttataccgt
     5641 ttgatgtttc tgcttttagt tcagctcaaa aaatggtggg aagtatcaat agtttttcgc
     5701 tgatcgctat tccgtttttc gttctctcgg gcattatcat gaataatgga gggatagcta
     5761 agaaactagt ggattttgcg atgttgttcg tcgggcgcgt gccgggggct ttggctcata
     5821 cgaatgtgtt agggaatgct ttatttggtt ccatctctag ctcggccatt gccgcttcta
     5881 ccgcgattgg cggagtgttg atccctcagc aagtggaaga aggatatgac cggaagtttg
     5941 cgacagcggt caatatcgcg tcagctccga caggtatggt cattcctcca agtactgctt
     6001 ttatcatgta ttcacttgtt gctggtggtg cttcgatctc tgctttgttt atgggaggtt
     6061 atctcgtagg cgctttgtgg gcgctaggaa tcatgctagt agcattcatc gttgctaaaa
     6121 agaataaata ccctgttgtc gaaaaaggac agatggctca tgctggaaaa ataataaaag
     6181 aggcgattcc tagccttcta ttgattgtca tcattatcgg tggtatcttg acggggatat
     6241 ttacagcagt agaagcttca gcgatagctg tcatttactc cctgttgatt gctatgtttt
     6301 actataaaac ggtaaaacta aaagatatac ctaatatgtt gtttcaatca gtagcaatgt
     6361 cagggacgat catgttctta ttggctactt cttccatgat gtctttcgcc atggcgttta
     6421 ccggtattcc tcaggcaatt agttcgttga ttatgggcgt aacggataat aaatttatta
     6481 ttctgttatt agtcaatctt gtgttattac tggtgggtat gtttatggat gtggcgcctg
     6541 ctatcttgat ttttacacca atatttttac caatcgtcac aagtgtaggg gttgatcctg
     6601 tacattacgg gttgttttca atcatgaatc tgtgtgtagg ctccatcacg ccgccagtag
     6661 gtacaggact atatgtcggt gcaagtgtag gaggcgtaaa agcagaggca atgctgaaac
     6721 cgcttcttcc tttttatggg gttatcttag tcgtcttgtt tttgattact tacttcccgc
     6781 aaatcgtcat gtggctaccc aatatgctga gttaggagaa tagttatgtt gaacattaca
     6841 attagaggac atgatctttc cgaagtccaa acgatagaag atcttgcaga aaaaacaaaa
     6901 gaacaaggga ttcatacact gcagctcgcc ttaggtcttt cgtttcctga aacaccttct
     6961 ggcgcaaatg agatcaattc tgggatggga aattatgtca aacgagtttt agaaaagcaa
     7021 gaagtgaccg taggaatttt aagttgctat atcaatatga ttcatccaga tttaacgata
     7081 cgacaagagt tgctgacaaa gttcgagcag tatcttcgct atgcttcttc ctttggtgcg
     7141 tcgatggttg cttcggaaac tggatgtgtt ttgccggaaa tccaatatac ggaagaaaat
     7201 ttcacagatg aagcatttgc tgaagctgtg tccgttatcc gtcgcttggt aaaagctgga
     7261 gaaaaatacc aaatgatggt ggggatagaa ccaggtttga atcatccggt gtattcttta
     7321 gcaagggtag agcagctgat ccaagcagta gattcggact atctaggaat cattttagat
     7381 ccgaccaatt tgatcacaag tagtgattat caagaacaag tccaattggt agaagaagct
     7441 tttgaacgtt ttggtgaaaa gatatgtgcg gttcatttga aagattttcg tgtcgaacag
     7501 gaaaaaatcg tgccggtaaa tttgggagac ggtgtgatcg agtacacaaa aatcaaagaa
     7561 atcatcatga agaatcgtcc gtacctgtat gtggttcttg aagaaacaaa agatgatggg
     7621 attcgttatg gaagaagtct tcttgaataa tgtaaagaag acgttggtta actaatattt
     7681 agaatggagg gggcggggct agaagatgcc acgtctcttc ttttttataa gagtatataa
     7741 aagcagctct ttttgattac aaaaaacgtg gtataataaa attgtgcata agtgaacaaa
     7801 aggaggtgcg gcacatgctc caaaagaaaa tcagcggtga acaagtcaat acgatggttt
     7861 ctgatcagta tgaaatctat catgtcaaag atgtcgtcag ccaaaataaa acgatctatc
     7921 atcatcatga tttctatgag atccatgcta cattaaaggg agaagcgact ttttatttga
     7981 acggacgaca atttacgatc aaagcaggaa gtgtgctgct catccattcc aatgatttgc
     8041 atcgtatcgt ccgccaatct tcagatgtat tcgagcgtgt ctatatcttt gtcacccctt
     8101 cttttctaga aagtcgttcc acgccatggt ctaatctatc ggcttgtttt caaccaatgg
     8161 gagagaagag gagtcgtgta ttgcaaatag aacaggaagt attgaagcaa aaattatcat
     8221 ttatcgacca tcctcctgat aaaaaaattt acggtgaaga cataaaatat gaacaagctc
     8281 tggtagaata cttgattttt ctcaatcaag ttgtacaaaa agaagagagt gcgcaagaac
     8341 agaatgctgt agttcctaat gagcgtgtgg aacaaatgtt acaatatatc tcaaaaaatt
     8401 tatctcatcc gctttcttta gaggaaatgg aaaagcagtt ttttgtcagc aaataccata
     8461 tcacacgaga atttaaaaag tacactggat ttacgtttca tcagtatgta atgaagaaaa
     8521 agctgatcta tgccaagcac ttgttgcgag aataccgcag ctctagtgct gtatatagta
     8581 aaagtggttt ttcttcttat ccgcattttc tgaaagcatt caagagagag ttcggcataa
     8641 cgcctaaaga atttttgaaa cgtgatacac agaaacagtt ggttcattat gaacattttg
     8701 aagatgaaca atgagaatga tcactaaaaa ataaccgcag tagctgctgt tgtttacata
     8761 gaagcagaaa ctgcggttat tttattttta tctatatatt tcaaaatatt ttgaaaaaat
     8821 gacgtacata ttatatgaat cagctgaatt tacgaaagtc tctcggcgat agtcctgttt
     8881 ttgctttgaa caggcggcta aagtaagcaa aattctcaat ccctatttct tcggaaatca
     8941 ttcgaaccgt aaattctgta taccgaagaa ggtctttagc gtaagaaagt tttttgctga
     9001 tcaaataatc gattggtgga gaaccgataa atttggaaaa atctttgctc agctgatatt
     9061 tattcaataa gaattgttgt tctaattgat caagtgtaat cgtttctttg aaatgttcgt
     9121 ctaagtattg cttcagtttg taaacgtagg cgggaatatc ctcttcttcg aaatctagct
     9181 gatacttttg caaaatcagt tcattcagca actcgtggat agctacagag gactggaaat
     9241 cggtacgggc attcgtgcct tgttgcatgt ggatcaattc tgtgatcaaa tggtggatct
     9301 tgttttctga tggatcccct gttgaatgga aggtgttatg gccgtctttt gtgaactcct
     9361 gataaaatga ttggacgttc tgaccattca aatggatcca atccatttcc catggttctt
     9421 cgctgatcgt ttgataacgc tgatattctt ggcagtcaat aaaaaataag tctccagctt
     9481 ttagctgttg ctgattatca ttatatgtaa gcgaaccttt gccagacaaa gtaaacttta
     9541 tcaagtaaga aggtaaatgt gctcgttcag tatagtaagg gattggtgct ttgaagtaac
     9601 cgatttcttg gatataaaaa aataaattcc tgcttctttg tgtaggcgtc aagatcactc
     9661 tttttgagtc ttccgaccat gagtggttgg ctttttccca gtaatccatg taaacactcc
     9721 caacttgtca agataatgca attatatacc aaaatagtgt gaagcaaaat ataagattct
     9781 gtattatgat agcattgtta ataaatgata acgctttatt aataaagtgc taatcaacaa
     9841 taaagtaaaa gaggtggaga aatgaatcca acatttgttg ccatcgatat cggtgcatca
     9901 agcggacgac taatgaaaag tacgagggat gcaaaaggtt ctttgatctt ggaagaagta
     9961 caccggttca aaaacggctt tcggaacaaa gacggtcacg atcgctggaa gatcgattat
    10021 cttatcaaag agattttgat tggatttgaa aaattaaagc agacagggat tgatcgcctt
    10081 tttgcgggga tcgatacatg ggcagtcgat tactgtctga ttgatgaaca aggggatcgg
    10141 ataaatgatc cgattgctta tcgggacaag cgtaccaatg gagcagtaga acagttttct
    10201 gaaatctatt ctctagataa gttgtatgag cagacaggga ttcagatcca gcctttcaat
    10261 accttgttcc aattgtttgc tgaagaaaaa gaaaatttgg caaaagcaca taaattgtta
    10321 ctgatacctg attatttagg gtatgtcttt actggtaaca tggtgacgga gaaaactaat
    10381 gcatctacta tgcagctgct gaatgcaggg acaaaagaat gggaaataga acttcttgaa
    10441 aaaatcggtg tctcgaagga attatttcca ccattgacag agccgggaac gatactagga
    10501 gatctgcaaa aagaacaatt ttcaaaatat gatttgccag atgtgacctt tatcacagta
    10561 gcaagtcatg atacggcgtc agctgtatta ggaacgccag gtcaaggaga acgttggggt
    10621 tatatcagca gtgggacatg gtcgctttta gggattgaaa caaagatcgc caatgtttct
    10681 cgcaatgctt tttctgaaaa ttatacgaat gaatggggtg cccataacac ggtgcgtttt
    10741 ttgaaaaaca tcatggggat gtggttgatc caggaagttg cccgaatgca agagtacgag
    10801 tacagttatg cggaattggc agagcttgct gcaaaagaaa aaccgctgca gcaagtgatg
    10861 gaaatcaatg accctcgatt tttgaatccc ccaaatatga tagaagagat tcagcaatac
    10921 tgttttgaaa cagagcagcc agtccctgtc tcatcgggag ctatcgctcg ttgtgtgtat
    10981 gataatcttg ctctttgtta cgcacaagag ctgatcaaag tagaacactt aactggaacg
    11041 aaattggaaa agctgcacat cgtagggggc ggatcgaata atcgtctact gaatcaattg
    11101 acagcagatt atgccggaat cattgtagaa gcaggaccta gtgaagccac agcaatcggg
    11161 aatgttgcca tgcaaatgct cagtacaggt cagttttcga atatagaaca agcaagaaat
    11221 gtaatcaaac agtcgtttcc atgtgaaact ttttacccag atgaaaataa gcaaaacacg
    11281 atggaatggt acgtgaataa aatcaaagga gtaatcgtat gaacacgatt gaaagaaatt
    11341 acgaacaagc aaaagaaaaa tatgcaacta tcggtgtaga tacagatgct gtactagaaa
    11401 agatacagga catcaaaatt tctatgcatt gctggcaagg agatgatgtc aaaggtttct
    11461 tgacaccgga tggcgaattg accggtggaa tcatggcgac agggaatttt ccaggagccg
    11521 cacgaacacc tgaagagctt agacaagatc tggagaaggc ttattcgttg ataccgggca
    11581 aacacaaatt gaaccttcat gctatctatt tggatacaga agaatctgtc gatctaaatg
    11641 aaattgagcc gaaacatttt gaaaaatggg tagagtgggc aaaaaaagaa gaaatcggtc
    11701 ttgacttcaa tccgactttc ttttcgcatc caatgatgaa agacggcttt acattggctc
    11761 atccagataa agaagttcgt gaatactgga tcgaacacgg gaaaagaagc cgcaaaatcg
    11821 cggagtactt tgggaaagaa actgggcaaa caagtatcaa taacttttgg gtacctgatg
    11881 ggatgaaaga taatccgatt gatcgtttta ccccacggga acgtttaatg gaatcactcg
    11941 atgaaatttt tacagaagag ttagatgaac ggtatgtaca agatgcagta gaaagcaaac
    12001 tatttggttt aggcgctgaa gcttatacag tcggttccca tgaattttat atgggttacg
    12061 ggttgactcg tgacaaactt gtttgtctag atgctggaca ttttcatcca acagaagtga
    12121 tttccaataa attatcttca ttagctttat tcagcaaagg aatcatgttg catgtttccc
    12181 gtccagtgcg ttgggattca gaccatgtgg ttttgatgga tgatgaattg caggaaatcg
    12241 ctaaagaatt agtccgtaac gaattgttgg aaaaaacaaa tatcggtctg gatttctttg
    12301 atgcaacgat caaccgtatc gctgcttggg tcatcggtac gagaaataca caaaaagcac
    12361 tgctgaaagc tatgctggaa ccagttgagc gattgaaaga aatggagctg gcttttgact
    12421 ttacttcaag aatggcttat acggaagaat tgaaagattt cccgtatgcc gatgtatgga
    12481 attatttctg ttacaaaaat caagttccag ttggtttgga ttggctggaa gaagtccagg
    12541 aatatcaaaa agacgtgttg gaattaagaa aataggagtg tggctatatt gaaaaaaata
    12601 gatattttac aagcgcctta tgtgaaagaa atgatcgaaa cgacgtcgaa tctttatcgc
    12661 ttgggatggg atgaaagaaa tggcgggaat atttcttatt tactaaaaga agaagagatc
    12721 acaccgttct tggatcctga aaaagtgatc cgccgcatct cgatgatttt tgatgccagc
    12781 cgtttagcag gatgctattt tattgtaact ggttcaggaa gatattttaa aaatgtagcg
    12841 agcgaacctg ccgagaatct tggaatcgtt cgagttgctg aagatggcaa aacactggaa
    12901 cttttgtggg ggctggaaaa cgaatgcctt cctacaagcg agttgccaag tcatttcatg
    12961 agtcatatcg cccgtttaga agtagaccca gataatcgga tcgttatgca ttgccatgct
    13021 agtcatctat tagcgatgag ttttacgcat gaattagacg aacgttcctt tagtcgtacg
    13081 ctatggcaaa tgtgtacgga atgcttagtt gtttttccag aaggaatttc catcattccg
    13141 tggatggttc cgggaacaaa tgagattggg gaagcaacag ctgaaaaaat gaaagaaact
    13201 cgattggttt tatggccaca acatggaatc tacgggtcag gaaaagacat ggatgaagtc
    13261 tttggtttga tcgagacagc agaaaaggca gcagaagtct atacgtacgt caaagcgcaa
    13321 ggaccaatct tgcaaacaat cacggacgaa aacctgtggc atttagcaga tgcgtttggt
    13381 gtcactccaa aagcaggtta tttggaggaa gttcatacga aagcaggtgt ctgacatggt
    13441 gaaaaaagct ttttgcatga aagtttaccc agaaaaacaa gaagaataca aaaaaagaca
    13501 tgatgaactt tggccagaaa tgcgtacagc acttcgtgaa cacggggtca tcgactattc
    13561 gatctatctt gatccgagta caagtttgtt atttggttac ttagtgatcg aagatgaaaa
    13621 gttatgggaa aaaatggcaa atacatctat caatcaaaaa tggtggaagt acatggaaga
    13681 tatcatggag acaaatccag atgcctctcc agtcagttgg gaattgatgc cagtctttga
    13741 actgtagcaa caagcaactg ggcaaccggt tgcttggggt tctttcgttt ttattgtgaa
    13801 aaaaaataca aattaggagg aatagaaaat gagtaatcga atgattttaa atgaaacatc
    13861 gtattttgga aaaggagcga ttgagtcgat cgtccctgaa tttcagcagc gaggattcgg
    13921 caaagcagct gtcattactg acaaaggatt gatcgagcac ggtatagcaa caaaagtaac
    13981 agaacttcta gataaagcag caatcgctta tgctttatac gacgggatcg tacctaatcc
    14041 aacgatccaa aatgtaaaag atggagtggc ttttgttaaa gaggcagagg cagactgttt
    14101 gatcgcaatc ggtggaggtt cgccaatcga tacggcaaaa gccattggga ttattttgac
    14161 gaatccagag ttttcagacg tcattagttt agaaggtgtt gctgatacga aaaatccatg
    14221 tttacctata ttagctatac caacgacttc tggaacagca gcagaagtaa cgatcaacta
    14281 cgtcatcaca gatgaagtaa atcaccgaaa atttgtttgt gttgatcctc atgatatccc
    14341 aatcgtcgcg ttcatcgaca gcgatatgat gatgggaatg ccgaaaaaat tggctgcatc
    14401 aacaggtatg gatgctatga cgcatgctat tgaagggttt atcacaaaag gcgcttggga
    14461 aatgactgat atgctgcatt taaaagcaat cgaaatcatc ggccattctt tggaagtttc
    14521 tgtagatggc gatcaaaatg ggcgagaaaa aatggcatta ggacagtata ttgcgggaat
    14581 gggcttctca aatgtcggtt taggactggt acacgggatg gctcacccgt taagtgcatg
    14641 gtacaacatt cctcatggcg tagcgtgtgc agcacttttg ccaactgtca tgaaatataa
    14701 caaagaatat actggagaaa agtaccgtga gatcgctctt gttctaggga ttaaaggagc
    14761 agctgaaatg tctttagaag atgtaagaga agcggcttgt ggtgagatcg atcggttgag
    14821 caaagcggtt ggaatcccag aaaccatttc tgaattaggt gtaaaagaag cagatattcc
    14881 agcaattgca gaagatgctt tgcgagatgt atgcacacca ggaaatccaa gagaaacgac
    14941 agtagaagaa atcattgctt tatatcaaag tttgatgtaa aaacgaagcg gatcttcaac
    15001 attaaattgc ctgtaaagag aaatggtagt ttatatctgg atatctcttt taaattgatg
    15061 gtatttccgc tataattttt cttataaaga aataggagaa tattatatgg aaaataaaaa
    15121 gccttatgga actgtattga tcaaagcctc taaaatacta gactatttag cggaaaacca
    15181 agatgtctct ttgcagacga tcgcaaaggg tgtgggaatg acctcttcta cagtcttgaa
    15241 aatactagat actttgttga tgatcggcta cgtaaataaa aattcagaga aaaactatcg
    15301 tttaggtgca aagcttattc gctacgcgaa taaaaacatt gaacaaatcg atttggtaga
    15361 gttgacttta ccgtttttag aacagctgca gcaaaagatc gatgagacta tccacttagg
    15421 ggtattggac aacaatgaga tcttgtacgt gaacaaacta gatccaaaac atcaaacgat
    15481 ccgcatgtct tcaaaaatcg gaatcacccg accattatac aattctgcga tgggcaaagc
    15541 cgtattagca gaattcagtg aagagcagta cactgattat cttgaaaagc atccgttgat
    15601 cccttacaca gaatatacga tcaccaatgc attacggttg aaaaaggaaa tccaaacggt
    15661 aaaagaaacc cacatcgcat ttgacgatga agaaatcgaa cgtgatattt tttgtatagg
    15721 agcctcaatc gtgaaaaacg aacaaatcat tggtgcattt agtgtaagta tgccgaaata
    15781 tcgtttaaca gatgagacaa aagaacaaat aatcagtgcc ctcaagcaaa caaaaagcga
    15841 aatcgagcaa agaattcaaa aataatgaaa aaagcgtttg caatttttct tttctgccgt
    15901 ataatatggg tatagatttc caagttataa aataaaattt ctaaatagga aataggtgga
    15961 gaagatgaaa aaaattgata ttttatctcg attgaaaaac gccggagtga ttgcggtggt
    16021 acgcggaaaa agcaaagaag aagctttgaa tgcttgccac gcaatcatca aaggtggtct
    16081 aactggtatt gagttgactt ttacagtccc tcaagcagat caagtaatca aagaactttt
    16141 gtcattctac aaagaccaac cagaaatagt gattggcgca ggcacagtat tagacgctgt
    16201 cacagctcgc ttggctatct tagctggcgc agagtatatt gttagccctt cctttgatca
    16261 agaaacggca gagatgtgca atctgtatca aattccttac ttaccaggat gtatgactat
    16321 taccgagatc aaaacagcgc tgaaaagcgg ggtagatatc gtcaaactat ttcctggaag
    16381 cgcttatgga ccaagtatca tttctgcctt caaggcgccg atgcctcaag tcaatatcat
    16441 gccaactggc ggtgtgagtc tggacaatat gaaagagtgg ttcgatgctg gtgtcgtaac
    16501 agtcggagta ggtgggaacc ttttagcacc cgcagctaca ggagattttg acaaagtaac
    16561 ggaagtcgcg caacagtatg cagcaaaaat gaaagaaatc aagaggtagc tgcttatggg
    16621 aaaagtagtg acactcggag aaatcatgtt gcgattgtcc acagagcagg gaacccgtat
    16681 cgattcaagt gaacgattcg ctgcccatta tggcggaggg gaagcaaacg tagcaatttc
    16741 tttagctaat tacggacatg aagcgatttt tgctacaaaa gtacctgata acgcattggg
    16801 aaaagcagtc aaaaagcact tgcaatgtta tggagtagat acgaaacagg tattatctgg
    16861 tggatcaaga ctaggtactt attatatgga aactggtagt ggcgaacgcg ccgcctcagt
    16921 gatctatgat cgtgccggat caagttttgc tgaaatggat catttggaat ggtcgctaga
    16981 ggagttattc caaggaatag atatatttca tgtttcagga atcaccccag ctttgtctaa
    17041 aaaatggcaa aaaatgacga aacaggtgat agaagctgca aaaaaagctg gctgcctgat
    17101 cagcttcgat atcaactatc gtggaaaatt atggacacag caagaagcca gcgaagtaat
    17161 ccatcagctt ttacctttag tagatatctg ctcagctgga aaaatggatg ctctttattt
    17221 gttaggtatc gagaaagcgc cagaagcaga agaacaacct ctaatttatt attatcaaaa
    17281 aatgcaggaa aagttcccga atattcaggt gttttattcg accaagcgta ccgttcattc
    17341 agcaagtgaa aatgaattga aggggacatt gtggatgaac catgaatatg tggaatccca
    17401 agtccataga atcaccccaa tcgtggatcg agtaggtggc ggagatgctt ttgcaggtgg
    17461 cgtgctccat gggattttat ccaatatgtc tccgcaagaa atcattgatt ttgctacggc
    17521 agcttctgcc ttgaagcata cgatccatgg ggactgcaac caatttagtc aagaagaagt
    17581 cgcacaattt ttagcatgcg gctctggaaa aatcattcga tagaaggagt agaagaaaat
    17641 gcaagaaatg gaaacacgtt atacacacag tccagaagat atccgtcatt attcaacgga
    17701 acaattgaga aaagaatttt tagtagaaaa ggtatttgaa ccagggaaaa tcagtttgac
    17761 ttatacgcac aacgatcgaa tgatctttgg tggagtgaca cctactgaaa aagaattaga
    17821 aatcacatta gacaaagaac taggtgttga ttacttctta gagcgtcgtg aactaggtgt
    17881 gatcaatatc ggtggaccag gattcatcga gatcgatggg caaaaagaag aaatgaaaaa
    17941 acaagacgga tactatatcg gaaaagaaac acgacatgtt gtattttctt ctcaagatgc
    18001 tgaaaaccca gctaaattct atattagttc tgttccagct catcataaat atccaaatgt
    18061 aaaaatcagt atcgaccaag taaaaccaat ggagactggt gaaggcctga cactgaatga
    18121 acgtaaaatc taccaataca tccatccaaa tgtatgcgaa agctgtcaat tacaaatggg
    18181 ttatacgatt ttagaaccag gaagcgcttg gaatacgatg ccttgtcata cacatgaacg
    18241 tcgtatggaa gcttatgtct actttgatta tgccaatgaa gatacacgtg tgttccacat
    18301 gatgggcaaa ccagatgaaa caaaacattt agttgtagac aatgaacaag ccattatttc
    18361 gccaagctgg tcgatccatt caggtgtagg tacaagcaat tactcattca tctgggcaat
    18421 gtgcggagaa aatatcacct atacagacat ggatatggtg caaatggatc aattaaaata
    18481 agcataaggg agagaaaatg atggaattta gtatggatat gtttcgttta gatggaaaag
    18541 tagcattagt caccggtgct gtctatggta ttggatttga gattgcacgc tctttagcta
    18601 cagcaggagc aaaaatcgta tttaataact tgaatcaaga atcagttgat gaaggtatag
    18661 cgcattataa agaagcaggc atcgatgcaa aaggttatgt ctgcgatgtg accgatgaag
    18721 aagcggttca agcgatggtt caacagatca aagaagatgt aggttcagtt gatattctag
    18781 tcaacaatgc agggatcatc aaacggacac cgatgatcga aatggatgcg gcagacttcc
    18841 gccaagtaat cgacgtggat ttaaatgccc cattcatcgt ttcaaaagca gttattccgg
    18901 atatgatcga aaaaggcggc ggtaaaatca tcaatatctg ctccatgatg agtgaattag
    18961 gacgcgaaac ggtcagtgct tatgctgcgg caaaaggcgg attaaaaatg ctgacgaaaa
    19021 acatcgcttc tgaatacggt caatacaata tccaatgtaa tggaattgga ccaggttata
    19081 ttgctacacc gcaaactgct ccattacgcg aaacacaaga aaacggtgaa cgtcatccat
    19141 tcgatcaatt tatcgttgga cgtacgccag cagcacgctg gggcgagcca atcgatttgg
    19201 ctggaccatc tgtcttcttg gcttctagcg catctgattt cgttaacggc catgtcttgt
    19261 atgtggacgg aggcatactt gcctatatcg gaaaacaacc ttaaaagagc tttagtacac
    19321 tgtttagtgg agaggttgtg aaatcagcgg attgaacgaa taccgaagga cagctgatta
    19381 aacatcattt attcgaaaaa agaggctggg acagaagcat ttaactccaa gaaataagaa
    19441 ggaattcacg aaaattgctt ttcaaatttt tgtgaatttc agcttatttc cgaaggagtt
    19501 gcttttactt ccgccgtttg tacgtgttta gagcgtgaga caaaagtgtt ctttactttt
    19561 gtcccacgct cttttctgtg cgtcttccat acttcactaa gtcgatccct cttgcttcgc
    19621 accaatcctt cactggtccg gaaaagatca gagattgttg gtgtagggcc gcggtattcg
    19681 ttgcgccgac catagtataa agcagacgaa gctcttcttg ccattgcttc atcagtataa
    19741 tagtttcttc tacgccgtga ttcatcagat gcgtcagtac ggttcctgaa gtacccacgg
    19801 catttgcgcc gagacaaagg gctttaaata tgtcataggc attgcggata cctccggagg
    19861 ctaggatttc catagaagtg tctgcttcat ttgcttcaag caatgaagag actgtcgatt
    19921 gcccccagtc agctaaataa ctcagttccc gcttggagcg acgggcgttt tcgatctggg
    19981 tgaagcttgt tccgcttcga ccgctgatat caactgtatg aactcctaaa gcagctagat
    20041 cattgagcgt ttctcttgtc atgccaaaac cgacttcttt tacgatgagg gggacgtcaa
    20101 tggctgtttg agtttcttga ataagtactt tccaattggt aaaatcacgg tctccctcag
    20161 gcataaccaa ctcttgaggt gcattcaaat gaatctgtaa ggcatctgcg tgaaacaatc
    20221 ggatagcttc tttggctctt tcgacagaag tccctgcacc gatgttggca atgattttcc
    20281 cgtgaggata ttcttgtcgc ataatcgtat aagtatcggc taaagaaggg actttcaagg
    20341 cagcgctgac tgaaccagtg gcaatcatca aatctgcttc tcttgcgacg attgcaagat
    20401 cttggttgat tttttttgtt ttttcgcttc cgccagtcat cgcattgata taaaatgggc
    20461 tgcttagtgt aaacccaact gcctgtgtac ttagatcgac atcagaaact gctatttgcg
    20521 gcaaagggtt atggatgatc cgtacgaagt caaattcgtt tttttgttta tcatgaaagg
    20581 ctttagctag tgaaacatgt tcgtcttttc gattcatcgg ttttcctttc tttgatcgct
    20641 atagacatgt aacggcagtg gagtgatttc tgctttttcc catgcactca ttaaaggaag
    20701 aatgccagat ttctggtcaa caattacgat tccgcaatcg cccccacctg caccagaaga
    20761 ttttgcggct ccttcatact gttcagctaa attacacaat ttgttcaaag caggcgtttc
    20821 gatgacgacc ccagtgattg cagataaatc atgcagtaat tgtcggtttt ttcgaatcat
    20881 ctgttggatc aacgttacat tattttcttt aaaccctttg atcatttcgt tgacacattc
    20941 tgtactattt tttaagaaaa gctgataagc caccatttta tcttctctcg aacggtgaac
    21001 ttgatcgacc aaatcagaag tagaggcagg gctacccgtc caaccaatca ataaacgtaa
    21061 atcttcagga gcaatcaatg gctcaatgga tagacctggc caatccaggg caagtaactc
    21121 actgatagaa tgctgagttt cttgttcttg gagccaagga tggtcgaagg ttgagaaagc
    21181 gatccagcca ccataacagc tagcagcgat gtcgccgcag gaaccattat cttgaactgc
    21241 taaattggct agtgctgcaa tcttgaaaat ctccaactga gataaattca acgcgtaaaa
    21301 aacattcaag gctttgaccg ttgcaacggt cacggcaccg ctagaaccca atccatattt
    21361 ccggccattt gaactgtcta actcacttgt tactttcaga tcataaaagg ataaaagaat
    21421 gtttttttct tgtgcatact tttcagtcaa gcgaatagca gcaaggatat aatgaaaagg
    21481 attttcccga atatctaaaa ctaattctcc gttgcgtctt gtccaacgta caggcatccc
    21541 actatattgt gcagattgga tacttccgac ttttcgtgca gattctacag tgactgtcac
    21601 gaattgatcg actgcagcga taactgctgg atggcctgtt tcaacaactg catattctcc
    21661 ggcaatatag agtttgcctg gtgcagatac ttcaatcata aaaatctccc tttattcaat
    21721 aatcgcaatt cctggaccag catgtgcagt aattacttgt tctttgctaa ataatttggt
    21781 aaatgtttct tgtacctcag ataaatggct gttttccact aaaactttga cattagggcc
    21841 agcatccatc gtaaagtagc atggaatgcc ttgctttctc aattgtcgca ccgcatccat
    21901 cgcttttaag ctgtcaggag accagtaagt gaatggaggc tgggcagcta aagtcgttcc
    21961 atgcattttt agtccgtttc tttccatcgt ttctccgaga agttggaaat cttttgtttt
    22021 gattgcttgt ttcaattgat atagatcccc ttcaacggaa tctaaccagc cttgataaaa
    22081 actggatgtt tcgactgtcc gacgcatccc atttctgctg gacacttctt ttttctggtc
    22141 gttgatcaaa acgaaaacca ttgctaaatc gtcttcgaaa gaatcggaag ggactggctt
    22201 agcgtaagaa cttaagtcgt catggccttt ttcccattcg acgaaaccac cgaaaatact
    22261 tcggcaagct gaaccagacc cgcgtcgagc aaatcttgaa agagagagat catctaatcc
    22321 aagcttaaga gcagtattgc aagcgcctgc taaagcagct agcccgctgg cagaggaggc
    22381 taatccagct gcggtaggaa cgaaattctg actgattact gaagctttta gtgagaggcc
    22441 ggcttcttta cgaaaaaggt caagaaactg actgactttt tttgttgctt tttcgtcttg
    22501 caaggtgcca tctagataaa attcatctac catatagcta tcagaaaaga tgacttctgt
    22561 ctctgtataa aatgcatcca atgttaacga aaggctgttg ttcattggaa ggatgagttc
    22621 ttcatttttc ttaccccaat atttgattag agcaatgttg gtatatgcgc gtgctttgcc
    22681 tttaaacata ggtatgtact cctaatcctt gtatccaagt ttcagcagca cccgcatctt
    22741 caagtgcttg actgatttct tgggcttttg tttttgtttg tgctaatgca atcatacagc
    22801 caccgcgtcc accgccagtt aatttggcac ccaatgcccc ggtatctttt gctgtttgga
    22861 tcaatagatt aagaaaatca ttgctgattg tcagcttttc cagaagtgat tgtgattcat
    22921 ccattgtctg tgccaacgtt tctggtgaat tttcaatgat tgcttgtttt gcttgcttcg
    22981 tcaagtatcc taatttttgg atcatttgtc cagtttcatg aggctgggtt tcaaagaggt
    23041 gagcgacatc tttgacggct tctcttgttt gtcctttgat tcctgtatca gcgacaatca
    23101 aaaaagcatc gatgttcaaa gaaaagtagt cgaaaggatg cccttttgta aaataaatcg
    23161 gctgcaagct gctagtagcg gctgcatcga ttccactagg attaccgtgg gcgatttttt
    23221 ccgaaagctg gacattttct aatagtattt cacgagacaa aggaaatgct aagtaatcat
    23281 aaaaagcacg agtgactgct gtggcgactg cagcgcttga tcccattcca cgttcagcag
    23341 gaatcgtgct ttcaatggtc agttgcaagt ttttttggat gtcatgctgt ttttttaagt
    23401 gaatgaataa ttttttgata ttttttaatg catgaggagc ttcggctaaa tttcctgaat
    23461 agtaggaaga aaccagttga tcgtccattg catccagctc ttcaaggaat gcggtgactt
    23521 ttgttgcata gaaaggaaag gcaatcgctg gttctccata aacaaccgcg tgctcgccca
    23581 tcaatatgat ctttccgctt gattctcctt ggccatagtt tgccataatc taactccttc
    23641 tcacgtaaaa gtgattttta agcaaaaaat aaagcgccca aaacgagttg cgctgcttca
    23701 cgaatttttt tgtccactaa gggtctcaaa aaacattcct cctttatttt actaaaacca
    23761 tctcagaagt aaaactaaga atacgttttc taaagaaaaa acactttttt cttaagaatt
    23821 ttttgacttt ttttcttctt tgactagaaa aaaatacaat tgacactact agatattggg
    23881 ggtatattta aaaaggttgg agttaaacac aatatttagt gatgaagtga gctggaggta
    23941 aatgagcgtg atcgttttag caggtacaat tggtgccgga aaatcaagtt taacagaaat
    24001 gatggctgaa cactttgata gtcaggcatt ttatgaatcg attgatgata atgaagtctt
    24061 gcccttattt tatgcaaacc ctgaacagta tgcttttttg ctgcaaattt attttttgaa
    24121 taaacgtttt gcaagcatca aacaagcaat gaaagatgac aataatgtat tggaccgttc
    24181 gatttatgaa gattcactgc ttttccatct aaatgcagat ctaggaagag caacagaaac
    24241 agaagttcgt gtgtatgatg aactgctgga aaacatgatg gaagaacttc cctatgctgc
    24301 ccataaaaaa catccggatt tattagttca tattcgtgta tcttttgata cgatgttgga
    24361 gcgtatcgaa aaacgtggtc gttcgtatga acaattgtcc tttgatccaa gtctatacga
    24421 ttattacaaa gaattgaaca gacgttacga tcaatggtat gaagaataca aagaaagtcc
    24481 aaaaatccaa atcgatggag accgctataa ttttgtggaa gatcctcaag caaaagaaga
    24541 agtcttgaaa atgatcgaag aaaaattagc agagattcgc caaaccaaag tagccatttg
    24601 atttacagtt gctcaaataa agggtaaacc tttatttgag cgactttttt ctttatactg
    24661 gaaacaaatg tcaggaggat agagtatgcg ggaaaaacac tattttaatc aagaccgtaa
    24721 tttttggatc aatgtacagc aaaacgatgt gctagctgtt aaaaacttaa aagaagaata
    24781 tggcattagt gacgagatgc tgacttattc tctagataaa aatgaacggg cgcgcgtaga
    24841 gtacgattct tttgatgaag cgttactgct tgtatcaaat gttccgcacc agcaaaaagt
    24901 cgataatcat tatgaaacta gtcctatcgc ttttatttta aaagaagacg gtttgtttac
    24961 atttaccacg ccgaataccg agtacgtgat tcgactaatt cgatcgcttt tggaacgaat
    25021 gccagacatg agtgtataca gtttattgtt tcgtacattg tttttgattt ctgattcctt
    25081 ttttccttta atcgaggaag tgaatagtga acgtcagcgg cttaatctga aattaagaga
    25141 aaaaacaacg aacaagaatc tgctgcaact ttcagattta gagatcggtt tggtttactt
    25201 agttacagga acaaaacaaa atgtagtact tttagaacaa atcaaggcat tggctattta
    25261 tcgcaagttg tcagaaaagg aaaaagaaga gttggacgat gcgctgatcg aagcacgaca
    25321 agcagttgaa atgacgaact tagcttcgca gattttagac cagctctctg gcacttataa
    25381 taatttgctg aataacaact tgaatgacac gatgaaattt ttgacggtct ggtcgctgat
    25441 cttgaccgtt ccaactattg tgacaggatt cttcggaatg aatctccagt taccctttac
    25501 ccattccgtt ttcggatggg gaatcgcctt gatcatcagt ttggtcttat ctatttggat
    25561 gcttattgca ctgtggcggc ggattcgttg atctagtctt tgatctgcaa accaagggct
    25621 tgggcgatca caagtgcttg ctcttggttg acgattagtc ccgccaaaga atcttgagat
    25681 aaagcgattg ctgtgaagaa attagtcgta aagtctaatc ccttcagaga agttcgaaac
    25741 cagttcgaac cggtcaactg attgtcagac aaaaaaaggt ttttccaagt gacctcataa
    25801 aattcgctgt cttctaattg acaatgatcg aaggagacag ctttcaagtt tgtactacta
    25861 aaggaagcca tcgaagcaat acaatcagtg aaagtacagt ctcgaagata actttcggca
    25921 aaattcgtac ctgttaattt acattgatga aacacgactt ggtggaaact gccaccaatc
    25981 cactccagat tggaaaaatc acatttttca aaaatgacat tactgcattc aaaatgacgt
    26041 aaaactgttt tttgcatcgt aagtttttgg atatgactct ctcttaatac catatttttg
    26101 gcatcgagat agctttggtc acccccgttg atcagaagac cagagaagat ctcctcatct
    26161 tctaaataaa actctccctt tgtaagaaga ggaagagaag gtggaatagg ttcgattttt
    26221 ttcatgtggg ttcacctcgt ttttctttag tatagcaaag aagcgggaat cactgctaga
    26281 aagtctgcta atctaatcat tttcagaaaa ggaagacaaa ctgtatgaaa aacattgaca
    26341 aaaagattag tttttgctat actatgatgg ttgagaaata aaagcagaag cacccgcttc
    26401 tcgccttagt tgataatgtc actgggctag atagttttca ctggttctat taggtgaagt
    26461 acgcgcgggt tctgtaagag aactcgtttt tttattgccg tttattcggt aagcttttct
    26521 ttctctcata atatttggag gtgaatgacc atagcaaagg atatgatggt taacgacggc
    26581 attcgtgcac gagagttacg attgatcggt tcagatggtg agcaattagg agttaagaca
    26641 aaagcagaag cattgaatat tgcagaacaa gcaaacttgg atcttgtgtt agttgcccct
    26701 ggtgcgaaac caccagttgc gcgaatcatg gactacggta aataccgttt cgaacaacaa
    26761 aagaaagacc gcgaagcgcg taaaaaacaa aaagtgatca atgtaaaaga agttcgctta
    26821 agtcctacga tcgacttgaa tgacttcaat acaaaacttc gtaatgcacg taagttcttg
    26881 gaaaagggcg ataaagtgaa agcttctatc cgtttcaaag gccgtgccat tacccataaa
    26941 gaaattggtc aaaaagtctt gaatcgctta gctgaagaaa ctgcggatat tgcaacagtg
    27001 gaacaaaaag cgaaaatgga cggacgcagc atgttcttga cgctggcacc gaaaaacgac
    27061 agtaagtaat ttgaatgact aactggctgt tggacagccg atagtcggat aacgaaagat
    27121 tttgaggagg aaatatagtc atgccaaaac aaaaaacaca ccgcggatca gcaaaacgtt
    27181 tcaaacgtac tggtaaaggc ggattgaaac gcttccgcgc gtttacaagt caccgtttcc
    27241 acggcaaaac aaaaaaacaa cgccgtcaat tgcgtaaagc aagcatggtt tctagtggcg
    27301 acttcaaacg tattcgccaa caactagcaa aaatgaaata agaagtacaa ataacagaat
    27361 ctgaagattt atttttatta ggaggaatta tacatggcac gtgttaaagg tggaacagta
    27421 actcgtaaac gtcgtaaaag agtgctaaaa ttagcaaaag gttactacgg ttcaaaacac
    27481 actttattta aaacagcaaa agaacaagta atgaattcat acaactacgc atatcgcgat
    27541 cgtcgtcaaa agaaacgcga cttccgtaaa ttgtggattg ctcgtatcaa cgcagcagct
    27601 cgtatgaatg gcttgagcta ctcaaaatta atgcacggtt tgaaagttgc tgaaatcgac
    27661 atcaaccgta aaatgttagc tgacttggct gttaacgatg cagcagcatt tactgcattg
    27721 gctgaccaag caaaagaagc tttggctaaa taagctaaac aattataaag aggaaagaag
    27781 ataacgaaaa gttatgttct ttcctctttt tttatttaca atcctccatc aaatgaaaca
    27841 ggacaataac gtataagtct aaaatagcat aattaaggtt ttttaattga aaactgaaca
    27901 tttatggtca ccctttaatg aaagcgctaa ctacataagt tagaatgagt ttgactgata
    27961 tattagtttg cttatcagaa aaacaaaatg gacggaggaa taacatgagt gatattatta
    28021 ttggtatttt gttagttatc tcattctttt tcatggtctg gtactgtgta aaaggctaca
    28081 acttgatggt cggctttgcc atcatggcta ctgtatggat gggattagcg ctagtcggaa
    28141 acacgttttc accaaacccg gcgatggaag ggcaaggagt aattgatgtg ttgacgcata
    28201 tctatacgac ggggccagct gagtacgcca aatcgatctt ggtaaatgtc ttctttggtg
    28261 cctttttcgg gcgtgttcta gtagatagcg gaatcgcagc taccctgatt cgaaaggtag
    28321 ttgaacttgg aggggacaag ccaagaatca cgatgagctt actatgtatt gtaaccgctg
    28381 ttatattcat gtcgatgaca ggaatcggac cagtgatttc tattgcagtt attgtgttgc
    28441 caatcttgat gtcattaggt atttcagtac cggttgcact gttctcattt atgggctcga
    28501 ttatggctgg aatctttgct aatatcgtca atttcaaaca atatcaaacg atttatgctg
    28561 gtttcaatcc agcggctgaa agctatactt ataatgacta tttccaaatt ggtatgattg
    28621 ggatgattgt aagcttagtt gtggtactaa cggtcgctaa tatatcaatg aacaaaaaga
    28681 aacgctatgc aatggcagca aacgtaccag ctgaaggtgg cgacgcacca atgatctcat
    28741 ggttagccgt attattacca gttttagggg tcgttctttt agatcttcca atcatcttag
    28801 gttttattct agcaggtatc tgggcattgc tgtttactgg aaaattgcgc ggaggttata
    28861 aagaaatctg tcgtcagttt gcgaaattat ttacagatgg cgcagtagat gttgcaccaa
    28921 tggttggttt cttgatgacc ttagcgatgt tcaataattc agctgcgtat gcttctcctt
    28981 atttttcagc tatttttgga gattggatac cgcaatcacc attagtcttg gcaatcgtat
    29041 ttgctatatt gacaccacta ggatttttcc gcggtccaat gaatctagtc ggttcaggct
    29101 cagctatttt agctgtcgta ttagctgtta atccaacgat gtcgccagcc tttttgttcc
    29161 cgttatttgc aatcacaacg attgctcctc agcatttaga tattacacaa tcttgggttg
    29221 cttggggatt aggttataca aaagtaactt ctcgagaata tatgaagaaa tccatcccaa
    29281 ctggttggat catcggagcg atcttatgcc tgatcacgtt cttattgtac gggaacgcct
    29341 agtaaacaaa acgtcgataa aaacgattag atgaatggag gaaaagaaaa tgaaacgttt
    29401 tgtgcgaatg ggaattgatg ttggcggtac acatacgaaa gcagtcgcaa tcgataatgc
    29461 gacgcacgaa atcatcggaa aatcttcagt gaaaacaacc cacgatgatg tccgtggagt
    29521 agccgcaggt gtcgttcagt cttttcaaaa ttgtttgcgg gaaaataata tcagtccaga
    29581 agatgttgtg tttgttgcac attctaccac acaagcgact aatgcactga ttgaaggaga
    29641 cgtagcaaaa gtcggcgtaa tcgggatggc aaaaggtgga ttagaaggtt ttttagcaaa
    29701 acgacaaact agattgaacg atatcgattt agggaataag aaaaaaatag agattgtcaa
    29761 tgcattctta cctgtcaaac acttaaatgt agaccgtgtt tcagaaacga tttcttcttt
    29821 agaaagagaa agagcggagg tcttggtttc ttctatggca tttggagtag ataatgggga
    29881 accagaacga gttgtttatg aagcagcatc ggtaaaatcg atccctacaa cgatggcttc
    29941 tgacatcaca aaattatatg gattgacaag aagaactcgg acagcagcaa tcaatgcatc
    30001 tattttacca aaaatgctag atacggcaac ctctacagaa gattccgtac gagaagcagg
    30061 ggtcaatgtt tctttgatga ttatgcgcgg agacggcgga gtaatggaaa tcaatgaaat
    30121 gaaaaaacga cctgttttaa ccatgctttc cggtccagca gcatcagtca tgggctcttt
    30181 gatgtacttg agagcgtcta atggtgttta ttttgaagta ggcggaacaa caaccaatat
    30241 cggggtcatt aaaaatggac gtccagcaat cgattattca attgtaggtg gccacccaac
    30301 atatatctct tcattagatg ttcgggttct aggtgtggca ggcggttcga tggtacgggc
    30361 taatcagtca ggaatcatcg atgtcggtcc acgttctgca catattgccg gtctagatta
    30421 tgcagtattt acggagacag aaaaaatcaa aggtcctaag gttgaatttt tctctcctaa
    30481 agaaggagac cctgctgatt acgtcaaggt agtgatggaa gacggagaag aagtgactat
    30541 tacaaataca tgtgcagcca atgtccttgg attagtgcaa gaagaacatt tttcttatgg
    30601 aaatgtccca tctgcacgaa aagccatcca agcattagct gattattgtc atacgacggt
    30661 tgaagacatc gcagaacaga tcatggaaaa atcctatgct aagattgaac cggtgatttt
    30721 agaattggca gacaagtatc acttggagaa agatcagatt tctcttgtag gtgtaggggg
    30781 cggcgctgcc tcattgatta cttactttag taataaaatg ggtgtgaaat attcgattcc
    30841 tgaaaacgcc gaagtgattt cttctattgg tgtagcactt gcaatggtcc gagatgttgt
    30901 agaacgtatc atcccttcgc caagtaaaga agatatacga tcgttgaaaa atgaagcgat
    30961 gaataaagcg attgaatcag gcgctacacc agaatcgatc gaagtccacg tagaaatcga
    31021 tccacagact tcaaaagtaa cggctatcgc tactggttct acggaagtga aagcaaccga
    31081 tctaaccaag gagatcacaa cagaagaagc actagagctt gctgcagagg atatgcgatt
    31141 aaataaaaat gaagtttgct tattggaaaa tacacctttc ttttatgtat gcggcgaaca
    31201 gaatcgttca aaaaatgctg gaagtcttcg gatcatcgat caaaaaggat ttatcaaggt
    31261 ccaacgtgga catgcttcat gtatgaaaac aactgcagcc aattatatga cagctgtcga
    31321 acaactttgg gaagatatgg cagtttatca aactgaattg attgcccgac cagaatttta
    31381 tctctgctta ggagcaagag tctctgattt tacagcgacg gatctggaac aactacagct
    31441 tttgatggat ctggaagtat ctactatgga accggaggaa gaagtgatcg tcgttgccgg
    31501 aaatatcaaa caaacataag ttagaagagt tactaaacga attacaacag atccccgaag
    31561 aaatttgggg attctaccag tttcggcgag atttattttg gaaaaagatt cctttgtcca
    31621 agcagaaaat tcttatacaa caatcaatcg attgtggtat cgaaacggca tgtagcatca
    31681 aaaaaaagta cccttttgcc gatgtaggag aaatttgtga acaaatggct gttccaatcg
    31741 tttcctgtga atcagagcaa ataaacgaac gaatcacttt tgcaacttat gcagaagatg
    31801 aagggattcg attgatgacg gagccgttag aaaaattaaa atgttcagga ctagcttcga
    31861 tctctaaaga aacagcgcaa gctttgatta ttggacatga actatttcac cacatcgaag
    31921 cttctgttaa gggaatttat acgcaaagcg aaaaaattgt gctgtggcgg ttgccttttt
    31981 atacacatca atcaaacatt cgtgcattga gcgagatagc agcgatgagt ttttcaaaag
    32041 agatgaatca aagcgatttt tcgccttatg tattagaggc agtcttactt tggccatata
    32101 atgaaattcg tagccaaggg atcttagaag aaataaaaaa aatagaaaaa agatgtacgg
    32161 agtatgattt agattacaaa taaagagact gtgacaaaag tcgtgtcaca gtcctttttt
    32221 tccgaataaa cgatgttctc ctgtcaactc ctcggtcaca agtcaaaata ttcaacaaac
    32281 atgagaagct gttttttgaa attgttcctt gtgactcgga gatgaacggc aggctcacga
    32341 cctcttggaa aacggtgttc aaaagcttgc atctgcggta ataagtccag ccaagttaaa
    32401 aacataagaa gctattttta cttggctgtt cttattactt gatgcagggc agctttttca
    32461 caacctctca ataaacggtg tgcaatcagc tgaccctcgg tattagctca aaaaaaacgg
    32521 caaaatatga ggaactattt tgccgtttct ttctctaata ctcaggtcaa aacgctgatt
    32581 ccaaaacctc ttatttgatg ggtctgtcct gaatatcttc aaaataatcg gggtaattat
    32641 gaatcacgta ttcttgctcc tcgataatca tatgtaaatg catcgtgcaa agaaatccga
    32701 cttcatcaaa gttatgatca atcattgatt gaagcattgt ctgatgttca tctaatactc
    32761 gaccccagtc taattctgaa atcgtcaaac gtaaccatct gaaacggttc aagtgcgtac
    32821 tataactttc tagccaatcc caaatttctc gttttccagc aatttcataa caagttcggt
    32881 gaaaatcagt atccaaatca aaaaaagctt ttttattttg agcgattact gcctgatcgg
    32941 tttttccaac ttttcccgcg tataacgggc taatgaagca gatcggatat cgatttttga
    33001 aacataagtg ccggactgtg gaatggtttt tacaagctct tgattgcgca gttggatcag
    33061 tgcttctcga atcggtgtac gcccgatagc tagttgttct tctaacactt tatcggagat
    33121 tttacttcca ggtgctaact cggaataaat gatttgttta cgtatagatt cataagcttg
    33181 ctgttgcaaa ttattgataa ccatttaacc ttcctttcta tgcagatata atctattata
    33241 acataaatcg cttacaaatc gtgtgggcat aaaaacacag tctgcaaaaa aagccctgat
    33301 aggcatgcct attagagcct cgaaaagaaa aatattgaat caatctggtc gtacctcttg
    33361 tatcggtttg acacgaccgc cgattctttt agcaaaagct tcggattctt ttttgtcttt
    33421 gaaaatgagc agattgtcta agtttttttc ccgagtgcga cagccagttt tatcgatgta
    33481 accgtgcatt actttaacga catacatggg gatcacctgc ttttttcttt tcattatacg
    33541 aactactcga cacaatacaa gaaaaatgct tagacggtct ttattaagaa tttacatcat
    33601 ccaaagaagc gtacgcttgg aataactgat ctaactccgg attgactttg ctcagcttca
    33661 ctaatcgttg cgaatcagaa agtaaaaaac agtgtttact actgccagta gtttttaatt
    33721 ttttgtcttc agttcccaca atttcgtagc taaaatccaa ccgtgtcccc gtatactttt
    33781 ggatagttgg atggatgctc actttttctc cgtaatggat catttcttta tagctgcaat
    33841 ttacttccag aacggggatg atgatcccag attcttcgat ttttttatag ggaaacccta
    33901 gatgtaccaa taaggctacc cgagcctctt caaaccagcg gatataattg ctgtgatgaa
    33961 taatccccat ttgatctgtt tcataataaa aaggttctcg cacataacct gtaaatttct
    34021 ccatgactca tgcctcgttt tccattgatt ttttacaaaa ataattcatc catttcggaa
    34081 gtgcttcgct gatttgtgtc ggcaaaacaa tatattgttc ttttgccagc tggtctccaa
    34141 tgaaactatg aagataaata gctgctgcaa tcgtttggtc attttgagga aactgggcta
    34201 aaaatcctgt gatcatccca gctaaagtgt cacccatgcc gcccgttgcc atagcagcag
    34261 aacctaaagg attggtgtag aagtgctggt gaccataaat ttttgtctca tgacttttca
    34321 aaacgagcac agcaccgatt tcctgttgct tctttttgtt ttctttatcc cgttgttctt
    34381 gtatcggtag agaactcaac cgttgccact ccatttgatg aggtgtaagt acagtttgtt
    34441 cgggataggg tagcaaaaga tgattagcag caagtaaact taaagcagag ccatcaatca
    34501 ccagccattg ttcttttgat tggttttcta gtacttgttt gaaacgttcc aaactcttag
    34561 aagaagtacc caatccggga ccaatcaaga gtacatctgc ttgctttatt acggaaagaa
    34621 actggtcagt atccgtccaa actacaatca ttgcttctgg cagatgactg tgaagagcac
    34681 tccgattttt ttcatcagtt actacagtcg tgagacccgc tccgctgtgt acggcagcta
    34741 aagcactcat aatgattgct ccgccatatt gttcattgcc gccaatcaaa acgatacgtc
    34801 caaatgttcc tttatgtgaa atttttggac gaggtgtgat gactcttttc actagttgtt
    34861 cgtttatcag catctaaaaa cctcctttta ctcattatag cgtatatttt ttttagagaa
    34921 aaacagataa gaaaaggaat tgtcagattt tttgaactat ttttttctgt aatttgtggt
    34981 atcatgaaca cgaagactta aataagtgga ggattaactt tatgacaatt gattggcaaa
    35041 aagaagtaga agcacgtaaa gaagacttgc ttgaagactt gaaaaatctt ttacgtgtca
    35101 acagcgagcg cgatgactca aaagtaacac cagatgcacc atttggacct ggacctcgcg
    35161 acgcattgaa acatatgtta gcttatggcg aacgtgatgg atttaaagta aaaaatgtcg
    35221 ataactatgc agggcatatt gatcttggcg aaggagacga aacgctaggg atatttggac
    35281 acatggatgt cgttcctgca ggagatggct gggacacaga tccttatgaa ccagtaatca
    35341 aggatggaaa gatctttgca cgcggatcaa gcgatgacaa aggtccaagt atggcagctt
    35401 actatgcgat gaagatcatt aaagaacttg acttgaaact atcaaaaaaa gttcgcttcg
    35461 tagtcggcag cgatgaagaa agcggctggg gcgatatggc ttattatttc gaacatgaag
    35521 aagaaccaga ttttggtttc tcaccagatg ctgaattccc aatcatcaat ggtgaaaaag
    35581 gaaatgtttc tttagcttta cgcttcaaag gcgacaatgc aggagattat gtcttgaaat
    35641 cttttgtttc cggacttcgc gaaaatatgg tgccaggaac agcaactgca gcacttcaag
    35701 taccaagtgc agatgcagct atcgcgatgg aagaagcatt ttaccaattc atcgaagcaa
    35761 atccagtaag cggaacgatt gaagcggaca atacgtatgt aaaaatcgaa ttagttggta
    35821 aaggcgcaca tggtgcaagc ccacaatctg gtatcaatgc aggttctttc ttggcattgt
    35881 tcttagataa ctatgaattc ctaggatctg ctaaacaatt tatccatgta gcagctgctt
    35941 atgtccatga agatttttat ggagaaaaac taggagtcgc ttatgaagat gaaaaaatgg
    36001 gcaaattgac aatgaatgct ggactatttg cttttgaaga aaatggtaca gaggaagcga
    36061 acttcatcaa tatgaatttc cgttttccaa aaggtgtaac agtagacgga ttgcaaagtg
    36121 acatcgaaca aacagtgggg caagaaggcg caacagttac tcgaggtgct cgcgtaatgg
    36181 aaccacatta cgtaccaatg gatgatccat tggtggctac attattgcaa gtctatgaag
    36241 accacactgg agaaaaaggc tacgaacaaa tcatcggtgg cggaacttac ggacgtttgt
    36301 tgaaacgtgg cgttgcttat ggagcgatgt tcccaggata tactgataca atgcatcaag
    36361 caaacgaatt tatgagtctt gatgacttgt tcagagcaac agcaatctat gcagatgcca
    36421 tctatcgttt ggcgaaataa ttaattaaaa agaggatcaa gaattgcaaa ttatttttgc
    36481 agtcttgatc ctttttttac tttctactgt ggtattcatg ataaacatga tatagattca
    36541 attcatattc tttcttagcg ttcgtgacga ctgtatccaa aatcaaccct gttactaatg
    36601 aaagaagtgc taaagtcatc aatccagtac ttaaaatcgc agaagggatg cgtgtaataa
    36661 agcttgtcag catatattcg cgaatcacag gaatccccgt gaccaatcca aataaaaaga
    36721 agaagatggt ccaaatccca aagaaaagca aaggcttata atctttaaac attttaataa
    36781 tcatcatgat cactttgaat ccgtcagaga atgtattcaa ttttgattcg ctgccttcag
    36841 gacgatcacg ataatcgatt gggatttcaa cgaacttgaa ttttttatct aaagcatgga
    36901 tcgtcaattc cgtttcgatt tgaaaaccag aactcataat aggaaaactt ttgacaaaga
    36961 tacgattgaa tcctcgatag ccggtcatga catcaagaat ttttgtttta tacattctag
    37021 taattgtatt tctaacaagg ttatttccaa aatcgtggaa aggtctctta ttctcatcaa
    37081 agtaggttcc atttgatagg cgatcaccaa tgaccatatc tgcttcacca gaacgtaatt
    37141 tctcgagcaa accatgtaca gcttctgcag gataagtatc atcgccatct accattaaat
    37201 aatagtcggc atcgatatca aagaacattt ggcggatcac atttcctttt ccttgacgag
    37261 gttctttttt tacgattgct ccaccttgaa cggccaattc gtatgttcga tcggtcgaat
    37321 tattatcata gacataaata tctgcttctg gtaattctcg tttaaagtct gcaatgactg
    37381 ttgaaattgt tgcttcctca ttgtaacaag gaatcagaac agcaattttt tcttgttgtt
    37441 ccatttttca ctctccttaa ctatagaaaa caaaagctaa attaaaaata cctcataatc
    37501 aaaggaaatg ctagtttttc ccgctaaata tcatttattt aaaaagaaaa tactggaata
    37561 tatgtttgga aagctctatc taaaaaacca cccactacaa aagaaggaca tgatacctct
    37621 cttttgaata gtgggtgcgt attcgttctc tcactttttt gacgtattaa tctgttgcac
    37681 ctttttttct tgaaatttct aatacggttc ctgtatgagc atctgctaaa aattcataat
    37741 aaacagtttc gccatcttct attcgagaaa gacctccccg ataagcactc gaccgaacgg
    37801 cgaatttcct aataggttcc ttttcaaaag agatccaaga accttcgatt gcaccttctt
    37861 ttagaaaaga tgacttgata ttttcaagta cttggtctgc tgacaatact tttttgcgat
    37921 gataccaaat cgttgaagct accccgctca ataatcctag accgattcca actgctaacc
    37981 cgcctttaaa atagcttagt tcgctttctt catacatgtg gacatacctc cttcttctca
    38041 cttgttactc cttgtgctta ttttaccaca ctctcatatt ttctttgaaa taaataaccg
    38101 ctaccagaaa aaataagcta taataaatac gatcggtctg cagaaaaaat catattttat
    38161 ccgcagatca atataagtct gagaggagtt tagtctgaaa tttagacgaa tagcatatgg
    38221 aagaaaaaac atttcaacga atcaaagagt taacagaatt acaaggaaca agcggttttg
    38281 aacaagatgt tcgcgcttat atggaaagtc atatggaacc gctggtagat gagttacagt
    38341 tagatggttt gggcggcatt tttggtctgc gccatcatga agaagcggat gcaccccgtg
    38401 taatggtcgc agcacatatg gatgaagtcg gattcatgct gacacaaatc caagaaaacg
    38461 ggctttttaa agtcgtacct ctaggcggct ggaatcctta cgttgtttct gctcagcgtt
    38521 ttacacttaa aacctctact ggtaagaatt atccatgtat ttcttcttcc gttcccccac
    38581 atttattgcg aggaacaagc ggacaaaaat cagtagaagt aaccgatatt ttgttcgatg
    38641 ctgggtttga atcaagagaa gaggcaatga gttacggtgt ccttccagga gacacaatcg
    38701 ttccttacgc tgaaacgatc aaaacagcca acggaaagaa tattatcagt aaatcatggg
    38761 acaaccgcta tggctgtaca atggtattag aagctttaga agcgttgcaa aatgaaacat
    38821 taggtcatac attgattgca ggcgcgaatg tccaggaaga agtaggcttg cgtggttcta
    38881 aagcttctgt caataaattc aagccagatc tgttctttgc agtagactgc tctgcagcag
    38941 atgatacagt gacgaaaaat ggcacattcg gacatttagg agaaggtaca ttgatgcgta
    39001 tccaagatcc aggtttgatc atgcttcctc gtttgcgcga gtacttgctg gatatcgctg
    39061 aaacaaacaa tatcccttat caatactttg tttcaaaagg cggtacagat gcaggtgctg
    39121 ctcatacaca aaacgaagga atcccaagta cagtgattgg cgtagtggga cgttatatcc
    39181 atacgcatca aacgatgttc agtattcgcg attttgaagc tgcacgagaa atgttgattc
    39241 aaacactgaa aggtttggat aaatcaacag tgaatacgat cgtatacgga aaataatgcg
    39301 atagtgaaac tataaaatct ggcaaaagat tgctttttgc cagatttttt ttataaaaag
    39361 aggatcaatg tttgttagtt cgaaagaaag gtgtataatt taattgaaaa atacataaac
    39421 agaaagtaga ggacaaagaa tgattatccc aaatagttta gaagaattag caggctacgt
    39481 agaaactgga aagagtgtat ttttctttac tgccggctgg tgcggagact gccgttttat
    39541 caaaccgcaa atgcctgaaa ttgaaaatga cttttctgat tggcaattta ttgaagtaga
    39601 ccgtgacaag tacatagatg tagccgctga atggaacatt tttggtatcc caagttttgt
    39661 cgtgatccaa gacggaaaag aattaggtcg tctagtgaat aaagatcgta aaacaaaaca
    39721 ggaaatcgaa tcgttcctag aaagtgtaac aaaaggctga catctgttag gaggggtcaa
    39781 gatgaatcaa gaatataaga atattttagt aggtatcgac ggtagtgaac aagcacttgc
    39841 tgctttcaaa aaagcggtag aagtggctcg ccgtaataat gggaaagtat atgtagcaaa
    39901 cgtaatcgat cagcaatttt ataactttat gggctatgca cctattgatc aaaatctagt
    39961 cgatcagcaa actgaaacag ccaaggaaat gatcgaagaa tgtaaagaat atgggaaatc
    40021 tgttgattac acaaatatag aaggaattat tgcatatggt tctgttcgtg aatccatggc
    40081 agtcaaattg ccaaaaaaat atgagatcga tctaatcatg gttgggcagt caggtctaaa
    40141 tgcagtcgaa cgctttatga caggaagtgt agccagctac gtgatacgtc attcaccttg
    40201 tgatgtcttg atcgtttctg acgaagaaga acagccaagt aattaagcaa gtggaacttg
    40261 tacgaccttt ttaatcaatt aactaaaaca gtaaagggac tgtgacaaaa gtcttgtcac
    40321 agtcccttgt tacgaataaa tggtgttcca gaagaggctt cttcggaaat aaagcatgaa
    40381 aaaaatttca tgcagtgaat gcaatttttt gttaagataa atctcagcaa aggataatgg
    40441 aggaaagaac atgatttttg cttataacaa agcacacgtc ggagacacct tgatggttat
    40501 tatagccgac gataaaggaa cagaaaacac tgttgaacgc aaatggaatg ttgctcggat
    40561 caaagatgaa caaggtcaag ttgttgcttg gaactttttc catatctccg atcatctaac
    40621 aatcgaaggg aacggccaag taagcttaac agatgaggaa ttagcgaaat tgaatcgatt
    40681 gatcaaagaa gcaggattcg aagaacagct tgaagctgat catgaaccga agatcgttgt
    40741 cgggtacgta aaaacatgcg tcccacatcc tgattctgac catttatcga ttactgagac
    40801 agaagtagac aatggtacag tattgcaaat cgtttgcggt gcacccaata tcgaagctgg
    40861 acaaaaagtt gtcgttgcaa aaccaggagc tatgatgcca gatggaatga tgatctggcc
    40921 aggaactttg cgaggggtag atagctatgg aatgatctgt tccgctcgtg aattgcattt
    40981 gccaaatgct ccagcaaaaa aaggaatctt agtattgcct gaggatgccg tagtcggaga
    41041 agcatttcca aaataaagag gttgtgacaa gtctttgtca caacctcttt tttattaatt
    41101 ttcactattt tgattttgtt ttaatgccga ttgatcgatc gtcaattcaa cagtagttgt
    41161 tttttctttc gagccttcat agtaagtgat tttgacagaa tctcccactt ttttcttata
    41221 caaagcagat tgaagttcta caccagaaga aacttctttg tcatcgatct tagtaatgac
    41281 gtcgtattgt ttcaatccag ctttttcagc cggtgtagct gtttggacat ttgtcacgat
    41341 gacaccgtta gttacagatg aaggaatctt caagatttgt tcttgttgct gagtagaaac
    41401 ggcagataag tcgaccattg tgatacctag agctggacgt gtcacttttc cgtctttttc
    41461 cagttgattg atgatattca ctacatcgtt acttggaata gcaaatccca ttccttctac
    41521 gcttacatta gaagtagatt cagaagtact tgcgatctta cttgagttga taccgataac
    41581 ttgtccttcg atattaacta aaggaccacc agaatttcca gggttgattg ctgcatctgt
    41641 ttggatcgca ttgatattga ctgtttcgtt cgattcattc gtacttgtca cttgtcggtt
    41701 caaggaagaa atgattcctg aagtgacaga atttgcatat tcagatccta gtggggaacc
    41761 aatcgcaatc gcaggctcac caaccttcag agcacttgag tcaccaaaag aggcaactgt
    41821 ttcgactttg tctgaattga tcttcaacac cgctaaatct gaataagcat ctgttccaac
    41881 taattcagct tttaccttcg taccgtcttt catcaagact tcaagacctt gctggccatc
    41941 tactacgtga ttattcgtga ctacataagc agtattcccg tcttttttgt agatcacgcc
    42001 gcttccttca ctataagctt ccaaattact atcatctgag ctgctacttt cttcttgctg
    42061 cccgaatagt ccgccaaaac cgcttgattg gttttgactt tgtaagttga taacagaaac
    42121 gacagcgtct tgaactttat ctaccgcttt ggtgatatca gaatctacat tgactttgac
    42181 attttccaca actgtttcac cggcagaatt ctgattgccg cttgtagcag tagaactatt
    42241 gttgccagtg cccatcgctg cataaaaaat gccagctgtc agtagtcctc caacgatccc
    42301 tccaacaagc cccagaccta acttacgcca gaggctatta tttttacttt ttttcatctt
    42361 tggtgtcaca ttttttctat ccatgtgttc ctcctccaat tacattcatt tatctactgt
    42421 tagtatagtc ttatttgttg actttagtct actttgagac tgtgaacttt ttatgaaaaa
    42481 ctttaggaaa aatcattgtt ttcagatgaa aatatttgat tttctttttc cacagatact
    42541 gtgtaaaact acgcggatag gattggaaaa ataagggata aaacatatcc acagcctgtg
    42601 tataaagtgg ataaattctt ataaaacgta tgtttgccta atgaatgtga tgaaataagg
    42661 taaaataaca ctgttttctg tggataaacc tgtggatgtt gtgcataact gttggggaaa
    42721 tctttttaac aaaaatagcc aaaataaaca tatagacgaa aaaattgatt ataataaaca
    42781 aagtgagcat gaagaccaaa ggagagaaaa catgaatatc aaaattatct cagtaggaaa
    42841 attaaaagaa aaatacctga tccaaggtat caatgagtat gtcaaacggc tgaatgccta
    42901 tgcaaaaatc gaattgatcg aagttcctga cgaaaaagcc ccggagaatt taagcgaagc
    42961 gcaaatgaga caagtaaaag aaaaagaagg ggaacggatc ttagcgaaaa tcaaagaaca
    43021 agaatacgtc tatgccttag caattgaagg gaaaaatcct acaagtgaat cttttgctaa
    43081 acaaatcgac caattaggta tccaaggaaa aagccacctt gtttttgtta tcggcggctc
    43141 tttaggactc agcgaagccg tcatgaaaag aagcaatgct cagatctctt ttggaaaaat
    43201 gacgtatcca catcaattga tgcgtctgat ccttgtcgag caaatctacc gtgccttccg
    43261 gatcaatgcg ggggcgcctt atcataagtg atgcggtttt tatcattgat cctaaaaatc
    43321 ttagcaagac aaaaagtacg taagaaagta aagactaaat acttcggagg aacaaatgaa
    43381 taacaatgat aggttattgc gattgcgtta tgcgattgat ttgaaagata cggatttgat
    43441 taaagctttt gagctaggcg gtgtaccact gactaaagaa gaagctcagg cggtactgac
    43501 caaagtacag gataagaaca aagataatgc agaaaataat gtgtatgaaa aaaccatcaa
    43561 caaccaagtt tttgacgcat tcctaaatgg cctgattctc ttggcgcgtg gtccgcaaaa
    43621 agataagccg atagtagaca cgccgcaaaa aagcaaggaa atcaaatata tcaacaatgt
    43681 gttgctaaaa aaattaaaaa tcgccttgtc tatgaccact gatgatattt tagacgtttt
    43741 tgctgaggca gaaatctatc catcaaaagg cgaaatcggg gcatttttga gaaaagaagg
    43801 ccaacgaaat tttaagcctt gcggagataa atatatgcgt aattttctca aggggttagg
    43861 aatttataat cggagaaaag tataaagaaa tttcatgaga aatcaaaaca atggttgttt
    43921 tgatgagagc tagtttttgt atgagattaa aatattatct taatcgagga gctggattgg
    43981 ttttatgaat gatgaatata agaatgatga agataagatg ctttttgaag agatagagaa
    44041 tcgatgtagg ctcaattttg agcttcgggg aaagatgtct ttaatacaac aaaaaaagta
    44101 tttagcgaat aaatcagagt ttactctggg acatgttgaa aaattaatct cggattggat
    44161 tagtagtaga agcgaattta caaaaataaa acagccgatt aaatttgaca tgaaaaaact
    44221 tttgttaaat aagagtgaga taggtaatag agatcaatat attagagcta aagggcaaga
    44281 aataattgat tcattaggtg aaatgaggtc atacaattat ttgtatgtaa cacatagagc
    44341 tgatggaatg gtcattactg tggggaaatc ttcttctaat gatatttttt tagatggaga
    44401 tcttttttat caactcaata caaatcactt gtctggcact gaaaatataa ttttaaggac
    44461 ggaatatggc aatgaaatat ttgcaaaata tgatgagatt ttaaaaaatt atttggactg
    44521 ggcttggata attccggttg agtcaggaga tgctaagaaa ctggagagat tattgggcga
    44581 tgaactaatt aataaaaaag taccaatttt aaattattat tcccatagac aataaaaggc
    44641 tatttttcat gataatacta gttataactg taaaaatgga agaaaatctg ggaaagaagt
//
LOCUS       DACCVZ010000016        44550 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.016, whole genome shotgun sequence.
ACCESSION   DACCVZ010000016 DACCVZ010000000
VERSION     DACCVZ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44550
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.016"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(14..1140)
                     /locus_tag="IVW63_000840"
     CDS             complement(join(14..912,912..1140))
                     /locus_tag="IVW63_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP7859136.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(2203..2544)
                     /locus_tag="IVW63_000841"
     CDS             complement(2203..2544)
                     /locus_tag="IVW63_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP7859137.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(2544..2774)
                     /locus_tag="IVW63_000842"
     CDS             complement(2544..2774)
                     /locus_tag="IVW63_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP7859138.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            3061..3399
                     /locus_tag="IVW63_000843"
     CDS             3061..3399
                     /locus_tag="IVW63_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859139.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(3604..3843)
                     /locus_tag="IVW63_000844"
     CDS             complement(3604..3843)
                     /locus_tag="IVW63_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HAP7859140.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTVISFARKIITQQMPELVMEKV"
     gene            complement(3819..4166)
                     /locus_tag="IVW63_000845"
     CDS             complement(3819..4166)
                     /locus_tag="IVW63_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF159 family protein"
                     /protein_id="HAP7859141.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(4898..5479)
                     /locus_tag="IVW63_000846"
     CDS             complement(4898..5479)
                     /locus_tag="IVW63_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7859142.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(5662..6288)
                     /locus_tag="IVW63_000847"
     CDS             complement(5662..6288)
                     /locus_tag="IVW63_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP7859143.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(6310..7641)
                     /locus_tag="IVW63_000848"
     CDS             complement(6310..7641)
                     /locus_tag="IVW63_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HAP7859144.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(7796..8197)
                     /locus_tag="IVW63_000849"
     CDS             complement(7796..8197)
                     /locus_tag="IVW63_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAP7859145.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(8283..8489)
                     /locus_tag="IVW63_000850"
     CDS             complement(8283..8489)
                     /locus_tag="IVW63_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859146.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(8584..10086)
                     /locus_tag="IVW63_000851"
     CDS             complement(8584..10086)
                     /locus_tag="IVW63_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAP7859147.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(10104..10559)
                     /gene="argR"
                     /locus_tag="IVW63_000852"
     CDS             complement(10104..10559)
                     /gene="argR"
                     /locus_tag="IVW63_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAP7859148.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(10657..11274)
                     /locus_tag="IVW63_000853"
     CDS             complement(10657..11274)
                     /locus_tag="IVW63_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859149.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            11495..12868
                     /locus_tag="IVW63_000854"
     CDS             11495..12868
                     /locus_tag="IVW63_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP7859150.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            12943..14055
                     /locus_tag="IVW63_000855"
     CDS             12943..14055
                     /locus_tag="IVW63_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAP7859151.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(14127..15764)
                     /locus_tag="IVW63_000856"
     CDS             complement(14127..15764)
                     /locus_tag="IVW63_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAP7859152.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(15932..16540)
                     /locus_tag="IVW63_000857"
     CDS             complement(15932..16540)
                     /locus_tag="IVW63_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP7859153.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(16924..18075)
                     /gene="queG"
                     /locus_tag="IVW63_000858"
     CDS             complement(16924..18075)
                     /gene="queG"
                     /locus_tag="IVW63_000858"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAP7859154.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(18094..18846)
                     /locus_tag="IVW63_000859"
     CDS             complement(18094..18846)
                     /locus_tag="IVW63_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859155.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(18987..19937)
                     /locus_tag="IVW63_000860"
     CDS             complement(18987..19937)
                     /locus_tag="IVW63_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAP7859156.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(19938..20777)
                     /locus_tag="IVW63_000861"
     CDS             complement(19938..20777)
                     /locus_tag="IVW63_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP7859157.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(20774..21520)
                     /locus_tag="IVW63_000862"
     CDS             complement(20774..21520)
                     /locus_tag="IVW63_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP7859158.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            21758..23128
                     /locus_tag="IVW63_000863"
                     /pseudo
     CDS             21758..23128
                     /locus_tag="IVW63_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736219.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            complement(23183..24079)
                     /locus_tag="IVW63_000864"
     CDS             complement(23183..24079)
                     /locus_tag="IVW63_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP7859159.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(24360..25037)
                     /locus_tag="IVW63_000865"
     CDS             complement(24360..25037)
                     /locus_tag="IVW63_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP7859160.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(25128..26033)
                     /locus_tag="IVW63_000866"
     CDS             complement(25128..26033)
                     /locus_tag="IVW63_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP7859161.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            26208..27632
                     /locus_tag="IVW63_000867"
     CDS             26208..27632
                     /locus_tag="IVW63_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7859162.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            27678..28709
                     /locus_tag="IVW63_000868"
     CDS             27678..28709
                     /locus_tag="IVW63_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP7859163.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            28716..29903
                     /locus_tag="IVW63_000869"
     CDS             28716..29903
                     /locus_tag="IVW63_000869"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAP7859164.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            30059..31441
                     /locus_tag="IVW63_000870"
     CDS             30059..31441
                     /locus_tag="IVW63_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP7859165.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            31568..31798
                     /locus_tag="IVW63_000871"
     CDS             31568..31798
                     /locus_tag="IVW63_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859166.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(31998..32666)
                     /locus_tag="IVW63_000872"
     CDS             complement(31998..32666)
                     /locus_tag="IVW63_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAP7859167.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(32855..33652)
                     /locus_tag="IVW63_000873"
                     /pseudo
     CDS             complement(32855..33652)
                     /locus_tag="IVW63_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(33933..35312)
                     /locus_tag="IVW63_000874"
     CDS             complement(33933..35312)
                     /locus_tag="IVW63_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP7859168.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(35487..36656)
                     /locus_tag="IVW63_000875"
     CDS             complement(35487..36656)
                     /locus_tag="IVW63_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP7859169.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(36631..37782)
                     /locus_tag="IVW63_000876"
     CDS             complement(36631..37782)
                     /locus_tag="IVW63_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAP7859170.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            complement(37742..39103)
                     /locus_tag="IVW63_000877"
     CDS             complement(37742..39103)
                     /locus_tag="IVW63_000877"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAP7859171.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(39100..40101)
                     /locus_tag="IVW63_000878"
     CDS             complement(39100..40101)
                     /locus_tag="IVW63_000878"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAP7859172.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(40117..40812)
                     /gene="dapD"
                     /locus_tag="IVW63_000879"
     CDS             complement(40117..40812)
                     /gene="dapD"
                     /locus_tag="IVW63_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAP7859173.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(40818..41534)
                     /locus_tag="IVW63_000880"
     CDS             complement(40818..41534)
                     /locus_tag="IVW63_000880"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAP7859174.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(41531..42412)
                     /locus_tag="IVW63_000881"
     CDS             complement(41531..42412)
                     /locus_tag="IVW63_000881"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAP7859175.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(42415..43215)
                     /gene="dapF"
                     /locus_tag="IVW63_000882"
     CDS             complement(42415..43215)
                     /gene="dapF"
                     /locus_tag="IVW63_000882"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAP7859176.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(43202..44461)
                     /gene="lysA"
                     /locus_tag="IVW63_000883"
     CDS             complement(43202..44461)
                     /gene="lysA"
                     /locus_tag="IVW63_000883"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAP7859177.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
BASE COUNT        12441 a         9224 c         7943 g        14942 t
ORIGIN      
        1 ttagtagaga cggttaagcc attttttctt ttgctaattc ttcaaattcc tgtggggtta
       61 gatagtgaat cgagctatgg attcgatttc ggttataaaa tccttcaatg tagctaaata
      121 gcgctcgatt tgcttcttca aaatctgagt agctagtcgt gtagacttct tcttttttca
      181 atgaggcatg gaaagattcg attccagcat tatcataagg tgttcctttt ctactataag
      241 aatgccttat tttgttggtt ttaagccatt gttccacttc tcttgctgtg tattggctgc
      301 ccaagtcagt gtgtagaatc attccttctg gaatgtgata atgtattttt gctttattca
      361 atgtttgaat gacacaatcc acagtcattc gttttgaaaa tgtataacta ataatttttt
      421 tcgtgtgtaa atccatgatt gaagataagt aacaccaacc atttttctta gtaggaatgt
      481 acgtaatgtc agctgcccat ttctcacaga tcgtttcagt agaaaagtcc tgatttaaga
      541 gattctcttt tgaaatgatc ggtttattag acctttgagg tctatatttt ttaactacaa
      601 tcgaccttaa atttaattgt ttcattagct tttggacatg tttaagagat actgaaatcc
      661 cttcttttaa taaaacttga tggatctttg tggcaccata gcgttgttta ttcgtaaaaa
      721 aaattgttga aatcttcttt ttcaacttat tatttctgat ttctgtagct gtcaacggtt
      781 tattcttata aaaataatag acacttctag ggatttctaa taaccgacat aacaaagaaa
      841 cagtgtaatc cttacaccat ttttcaataa attgaacaag cgaatttagg ttttccgaga
      901 gaatatggct gcggcttttt ttaagatttc aagttcctca tttaaacgag cattttcttt
      961 tctcagttca gctacttctt ttccagtcag tcctgtggac tgatcaggta aatataaatt
     1021 cttccatttg taaatcgttg cttcagataa gccatattct ttcgctaacc ctcgaacaga
     1081 acgtccagtt tgattcagtt caacaatcat ttgtttaaaa ttttcttcat atcgggtcat
     1141 aaaaattcat cctctcgtag ataagtttaa tttattcttg tctctacgaa aagctgtcta
     1201 agatttgata ctaacaccac ttggaactaa tgtatcatta ataaatgttg aaaaattcag
     1261 caactcatta ctgtatgatt ttagcagccc aaccaacata taccctataa aagctaataa
     1321 gatggttagg aatcctttag aatttttact cattcataga cacttcctta aataactttt
     1381 attatagaag gtattgtaaa taataatatt gacaaaaagt gactcaaaat aaaaaaaacc
     1441 ttacattata ctggaatgaa ctgtattgat agtgtaccta aaagctctac tgacataaga
     1501 tcgtgtaatc ggtaaagtaa ttttattaat tatacgggat gtaatcaatt agagaataaa
     1561 ctaatcataa aaggtacttt tacattcata attgtcgctt tgagattcta ctttggttca
     1621 ctatctgacc caattgcaca ttttcgatca ttacaagtat tggtgtcgtt agaacaacta
     1681 aataaaaact agcggtagat ttttcagaat ctatgctaat ttctgtatgg atgttccagt
     1741 gatggcaaat ttctcttttc attgtttttc ttgtcgcatg atatgccttt ttgtgttatt
     1801 cagttaaact atagaaattc tttcctagac agatcttgat cccaaatttt acgtttttga
     1861 gcatcgatat agtttaaaat gacattactc atatctaaag agtttagatt ttttaggact
     1921 aaaactgtca gttgttcttt ttcttctttc tgttaaagta ttgtcgcgac ttttcgtata
     1981 cgttaagata tgtcgtgaaa aaacaagttt tgtgacacaa aaaaacgaat gacttgagga
     2041 aatcacctca atcattcgtt taaaatgcta tatattcttt agtttaagat acggaaatta
     2101 atgccatcga ccacactagt agaatgaacg acatttactt ggcctttttt taatttcgtt
     2161 atgtttagca tataaaaata ttatagagtt tacttacaat gcttaaaaca tatactgtat
     2221 aatctgatca attttagcca tgtcttgcaa tggtaagttt tctatttttt tgagttttcg
     2281 ttccttaaaa tcaagagatt ttaattgtgt aataattact tgtcctttta tatctagctc
     2341 ttcaggtaat gagtaacgtg tcggtaaatt ctttatagtg gaagtaattg gacatatgac
     2401 cgaaaacatt gttttacggt taaattcata acgagagacg actagtcctg gtcgtctttt
     2461 ttgaatttct tttcctacgg agggatcaaa atcaatccat acaatatcac cttttttagg
     2521 aatataaatt ctttcttctg acactataaa atttctctcc cttcaggagt taaatcttcc
     2581 cattcgtctt tctcataata ctcggcctct tccccaccac taaatggatc ttcaattttt
     2641 ggaactaacg taattgttcc atcatcagaa tacacaacga tatattcttg gttttctgaa
     2701 ggtttctttc cgttatcaga aggtaaagtt accactacag aacttccttg taatctagat
     2761 tttgtaacaa gcattatcat cactccctta ataaaagtat actatataac actaagtaac
     2821 gcaaaattcc cctttgtaaa ctatctagaa aattgttttg tttaaagtat atcttattgg
     2881 atataaatag aaataaattg tagccagttc attttttctt taactaaaaa aataatccaa
     2941 gaaacattga acctatggat ccaaaagcta cccaaatact atagctaacc ccccgctacc
     3001 ttcaattttg cagataaaac gctttgggag aaaatttcaa agacaacagg ccatcctatc
     3061 atgcccgatt ataaacaaaa agctggctat tccttttgct ctgacaaatt tcaattggga
     3121 aagttcacga aactagcagg tgaagaagtt tcaactgttc ggatcaaaga atgcccgctt
     3181 caaatagaaa cattggttca acgaatttca actagacaag actttgctat tgtagaacgt
     3241 gagatcgtag ctatttttgt agaagaaggg attttacatg atccaactca tatcaatgtg
     3301 gataaatggc aacctcttat ctataaattc agagaatata caactgccaa ccagtcgtta
     3361 actttgaatt ttagattcca agaattcaaa gagtcataat gataaacatc gttaggtata
     3421 aataaaaaag actcgcagca cgagtaaaaa acaaatagaa gctatacatt agaaaggtcg
     3481 actgtgaccc tatagatgca gtatatgcag cttatgagca tttcttctgt tctctttgtt
     3541 tttgggatct gtgctgaagt ctttttcgtt ttttgccgct ctttctttga aaaatcgatt
     3601 atgttatacc ttctccatta ctaattcagg catctgctga gtaatgattt ttcgcgcaaa
     3661 agaaataact gttacccaag gttcgatttg ttcttcagtc aagacaagcg gcattcggtc
     3721 atggattggt gcgactgtgc ggttaggttc agtagtcatt atgattgatt ctgccatttt
     3781 ttcatcctga tggctacgat aaaaaccgcc aatatacact attttttcct tatttgaaaa
     3841 cataaatttg tctttttctt cattccactc attgggaaaa cacaacgatt ttgcaaaaat
     3901 ggttgatgaa aggtcttttt ttcttctact gtctctgcac gggcattaat catcaattgt
     3961 ccttttttaa atccggtaaa tccccacttc atgatttccg gagtgaggat gttttcttcc
     4021 tcttttctta acgtcacaac aagatttgac ggaaaaactt ctccagctgc taattctgct
     4081 gcctgcttcg gttgtttcgt ctgggcttct cgataataat tctgaaggag ctctgactct
     4141 agatcaaaaa aataacgacc acacatccta atccctccca atcttttttt ctatcataca
     4201 ctgcaacaag aagttcgcac caacaaaacg ctttcaattt ttgtagaact aaaaaagttg
     4261 tgacaagtga caaactctcc agtgaatggt attctcctgc caactcctcg gtcacaagtc
     4321 acaatattca acaaacatga gaagctgctt tttgaaattg ttccttgtga ctcggagtga
     4381 aacggcaggc ttacgacctc tgggtaaacg gtgttcaaaa gccagtttct cggtattaag
     4441 ccaaatttat gcaaaaatgt agaaagctat tttcacaaaa tttttcttaa tactcgaaac
     4501 taagcgactt tttcacaacc tcttccttaa acggtgttca aaagcttgca tctgcggtaa
     4561 taagcccaac caaacgaaaa atatgagcag ctatttttat ttggctgttc ttattacttg
     4621 atgcagggca gctttttcac aacctctcca ctaaacggtg ttcaatcagc taaccttcgg
     4681 tattagctca aaaaacggca aaatatgagg aactattttg ccgtttgttt ctctaatact
     4741 caggtcaaag cgctgatttc acaacctcta atacacggtg ttccagaagt agcttcttcg
     4801 aaaaataagc cgaaatttca caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt
     4861 tcttgaagct gaccacttct gtcacaacct ctaattatta aagaaccttt tgcgaagtta
     4921 acaatctttc tttgatcaat tgaaaattct gcctaagtag tgatagatcc tgtgtgactt
     4981 tcaacaataa gatacttccc tggatttcag caatcaacgc tttggcttga cggtctgctt
     5041 cttcatcgga cagtttttct tcagaaagtg ccaggatatt ttgtttcgta tacttgaccc
     5101 attgattgac taattctagt agcaacagac ggtattcttc atccactgta ctcaactcaa
     5161 taatcaaatt acctacagga cagccatgat aagtgatctg tgtctcatga tcagcgaaaa
     5221 tccagtccaa catttcttct aatgcttctt ctggctgttt tccagcattt aagatgtctt
     5281 cgaacaattc tgtctgccat acgtccatat gcgcatggat caccgctaga caaacttctt
     5341 tttttgaaga aaagtaataa taaaattgac cttttcctgt atcagaagct gctagaatat
     5401 ctcggattga cgtttcatga tagccttttt tataaataag atctttggtc gcttccaaga
     5461 tcttttcctt tgttttcaat gatattctcc tttttcattt ctcatagtcc tatattatac
     5521 agtaaattca tcattttttc ttcttaatcg tttaaaaaag actgtgccaa attatctgac
     5581 acagccctca ctataaaact gttctcatat agctagatgt tcattgattc aagaactgcg
     5641 aggacaaaag caattcctat cttatgatag ttgctctaat acttcctctg ttgtcatcac
     5701 ttgatctgca ataaagccaa agttcgtcaa cgctgcatcc attgcttctt ggccaggagc
     5761 accaattgca tctgtcgcta ccacaacatt gaatccactc tctaccaatt cacgcatatg
     5821 ggaatcgcta cacaagtttc cgttcattcc accaagaatt actgtgtcga ttccattttt
     5881 tctcaattgg agcgccaaat cattgctttc tggtccaaag attttatgag gagagctgat
     5941 gatcgtattt tcatccaaat aaggtttcaa ttcttcgata aaatcggctc ctgaaccttc
     6001 ttccactgat tcatattgac tttttctagc aaacatctgc tgctcaagca tcatatgttc
     6061 tcctgcaccg ccaaattgcc atttatggtc atgtgggtaa aaataatgag gagaaataaa
     6121 gagtttgtat cctttttctt ttgcttgttt taccatttca atcatatttt cgatcgtatt
     6181 gtatttttct aagatatctt ttgtcaaacc aaagccaccg cctgctggtt tcaagaactc
     6241 gacttgcggg tcagtgagaa ctactgctgt atttttatta ttgaacatgg tggattctcc
     6301 attcgttatt tattttaata catcatttag agcttcactc attgtcggat gagaatagat
     6361 ttgatctctc aataacgtat aaggaagttt tccattcata gctagcgaaa tcaagttgat
     6421 gacttcatga gaatcttccg catagatact tgcccctaga atcaagtcag tttcagggtc
     6481 gactaaaact ttgaatacac ctttaggatc ttctaatact tgtgctttag ggacaccgct
     6541 tgtcatatac ttgaataatt tgtaattgac gccttgtgct ttggcttgtt tttctgttaa
     6601 acctacattg gataaagtcg gagtgataaa tacactgtaa ggcacagctt tccggttatt
     6661 cgttgttcgt ttattctcgc ccttcaactg atccataatg attcgataat catctagaga
     6721 gatataagtg aactgcaatc cgcctttgac gtctccaatc gcccaaatgt tgtctgcatc
     6781 tgtacgaagg tattcatcca cagcgattgc tccgcgatct gttagtttaa catctgtatt
     6841 ttctaatcca agtgatgctg tacttggttt tcttccagtt gcagccaaaa cttttgacgc
     6901 ttggattgtt acttcttggc catcttctgt aaaggtgacg gcagctgttg attcttggtc
     6961 tgctacttga tctacagata cacctagatg gaattcgatt cccgcatttg tcatgtcttc
     7021 taaaatcatt tgcgcgatat cttcatcttc acgtggaaga aattcagaat gggcatcaag
     7081 aacgacaact ttagatccgt attcattgaa cattgatgca aattccaagc caatatatcc
     7141 agccccgatg atcactaatt tttccggtaa ttgttcctga tccatcgctt gcgtagaatc
     7201 aatcaagtag cgacttgtat tcaatccttt gattggtaaa atgattggtt cagaaccagt
     7261 attgatgaaa atccgttcgc cttcaacaat cactttttca ccattattcg tcacttcgat
     7321 ttgatggtta gaaagaaaac gtgctgtacc gtccatcact gtcccagttg cctcatcgct
     7381 gatcatatga taatttttgg cgcgaagcat gcccgtcaat ttttctttcc gagcaacagc
     7441 ctctgtaaag tcgattcctc tttctccatt gaaaatcaat gatttagaag gaatacagcc
     7501 gatgttgata catgttccgc catacatacg tgttgacttt tcaacgacta aaaccgattc
     7561 accttttgaa gctaacgcct tcgctaaagt cttaccgccc tttccaaaac cgatcacaat
     7621 attttgatat ttttccatca tttttccctc gcttcttttt tacctaccga ttggtacaaa
     7681 aatatgataa ccgataattg tctattctcc aaatcatctg ctttatttgt caaaaaaaac
     7741 cagacaaaaa gcggtccttt cacgttttta gtctggttcg atttccttta ttcttctaaa
     7801 caatcgttac ttctacatcg atatttcctc tagttgcttt ggagtaaggg cagaattcat
     7861 gcgcatcttc tgcaattttt tgggcttctt cttcgctgat gccatcgata tgcacttcta
     7921 atactacacc gatctgatag ccgccatcat ctaaattata aagagagaca cgtgctttta
     7981 ctgtggactc tgctgtcatt cctgcttctt tgatcatatg ttgtaccgcc ccattgaaac
     8041 aagaagcata acctgctgca aataattgtt ctggatttgt tccttctgca tggattcctg
     8101 gaggagtgat tttcatatgc atcgagccat ttggtgcctc gacttctcca ttgcgcccgc
     8161 catggttgat cattgctgtt tcgtatgctt ttttcattgt actgctcctt tcgattgacc
     8221 atttgctact tggctataat tatagtgtat gacaagtaag gcgctttcta caaaaattct
     8281 gcttattcga ataccagaat gccgtcttct actatttttc caaaaaacaa aaaaatacta
     8341 ctcgtgaaca acagcgtcat atttgttcca aaataaatag caatcttttc tacataatct
     8401 tttatatgat tgattttaag atacatatat accagaaagt tgaccccata aaccaatact
     8461 gttaaaaaaa taaccatatt cgttaccatt ttttcctcct tttgctggtc tccctaccag
     8521 cactcgattt aaccatacca ctttttttgc cgtccaagca actagccttt caaaaagact
     8581 ggtttattct gctgttaatg attcaagatc agaaaaatgt ccgaataatt ttgctaattt
     8641 tactaacgcc aacttgttct ttccgaattc atcattttct atctgtaata ctagtaacgg
     8701 ctcatgtaag cttaaacgga tcaaaaacca gccgtttccg tatggctctt ctagatcata
     8761 tcgaatacct tcttcatttt ccgggtcgaa gttcatccct ttttcttctt ccaacagtcg
     8821 cttcatttct tctaatatct tgtttccttg ttcgcgtggt tcatcgctga acaattttaa
     8881 tcggatttct tgtacttcta cgggctgttt caactctttg atttgttcat ctaatgtgat
     8941 accttttctt tttaattctg gcaaaagcat caggatcttt gcgatgacat atgcaccatc
     9001 atccagaaaa tagttttcct tgaatgcagc gtgtccgctt gtttcgatgg ctagctgtgt
     9061 atctttccca agacggttaa gttctaatgc tttattgatt acatttcgat agccggaaat
     9121 ataacgaact tggatgcctc ctttttcttc aatgaatctt tgtagatgag aagaagtagg
     9181 ggaattcgtc acgattcttg ttcctggatg ctcttttaat acgattgtac ttaatactgc
     9241 gatcaaatta tttcgattga tcactgttcc agaagcactg acaactgcag aacgatccac
     9301 atctgtatcg aaaatgatcc caagatctgc ttcatttgct aaaacagcct gcttgatact
     9361 ttccatcgct tctttattat caggatttgg gatatgatta ggaaatcggc catctggttc
     9421 caaaaattgg gaacctgttg aatccgcacc taagctattc aatacttttt cagcaaagaa
     9481 tccaccagca ccatttccgg catcaacaat gattttccaa ccatttagtg gtttgctttc
     9541 tagtgttcca atcccctttt taatttttgt gactaaatct tgcgcataag gtgtcaaaag
     9601 gtctgctttt tctacgcttc cagtttgttc gctttttatt ttttgctgct gtgataggat
     9661 aaaagcaata tcttcttttt ctgctcctcc ttctgaggta aagaatttta ttccattata
     9721 ataataggga agatggctag cagtcagcat aaccgcagca tcgcacgaga actgttcaaa
     9781 ttgagtggac ataaacatag caggcgtagt agctaattcg aaatcgatga catgtatccc
     9841 ttgttctttc agactttgga tcaacgcctc tttcagtgct ggtccgctta tcctactgtc
     9901 atgaccaatc ccaatcgtcc attttttatt tggatcggtt gatttcttct ttttctttat
     9961 ccagtttgct agtccccagc cgatcttttt taccatgtct gtcgtcaagt ttacttcata
    10021 tccttcaact ggtaatgcga ttcctcgaat atccgatcca ttttgcagcg ctttcatatc
    10081 tttcatataa aagtcctcct catttattcc ctcatttttt ccagcttttc tgcaaatcgc
    10141 tgtgcttctt cttctgagcg gcaaataata atgaatgtat ctacaccggc catcgttccg
    10201 acaacttcag ggtaagccac ttcatctagc caattcgtta ccacatcggc accatttcgt
    10261 tcagtcaata cgataaccat gaactgaaca gactggatac gcaaaacctc gcgtctaatt
    10321 gctgtacgca aacgttcttc atttaaagaa acagatggct ggttaaataa tgtatagcgt
    10381 actattttgt tttcattttg actttttact aacttcattt ctcgaatgtc tcgagaaatc
    10441 gttgcttgag tcacatcggc gcctgcttca tgcagccgcg caagcagctc ttcctgtgtc
    10501 ccaataggtt gttctgtaat gatctggcgg atcagtgctt gtcgctgttt ctttttcata
    10561 ttagacacct ctcaatgttg attatagcaa aagataagta atatttcttc atattttggt
    10621 attttttact tttatttttt gttttcattc aggttgctaa cctttttcta ttttaacacg
    10681 caaaatcgtc ttcatttttt caggtgctga ttttcttgga tcgctgatgt aaatctcttt
    10741 gtgttcttta gaagctcttt catagccttc ttttgcgatg aatgcttcta atttctcaaa
    10801 cgttgctggt tcttcggcat agggcccgac gtgtaagatt tgggcacaaa gaccttcttc
    10861 catctttttg aatactactt gttctttcaa gtcttccgga agtttgctag aacgctgaat
    10921 ggcttcttgt gctatcgctt ctgtaacaaa gtcaggctgt cggatcatca attgataaga
    10981 aaaatgttct tttttcatca ctggttcatg caaatacttt tcttgcagtc cccattgtcc
    11041 ttccagtgga tagacagtat acatctgata atcaggaatc agccaatttt ttttaggcga
    11101 catgcgtatt gcatagctga ctgcatatag acaggctact cttcgtttaa agtcttcctg
    11161 attcgggtcg ccgatccctc tgatgctaaa gaatgatttt ttaggaacct ctagtatttg
    11221 cgggcttttt ttcatactat agctcttgtc tttacgccat tcaatttttt ccatttttct
    11281 tcctccgcga aattccattt agttatttat tatcatacct ctttttgagt gacttggcta
    11341 atcgtgttga cactattttt cagtttgtgc tagaataagt gaagtaaata aatcgtacag
    11401 ataacacgtt tcggcgtgtc gagagagagg cggtttctat ttttataata gaaatcactc
    11461 tcttttttta cgaaattttt tagaggtgat gtaaatgaca aaacaaaaac agctgctttt
    11521 agtacctgca gtaattgcaa cagggatgat gtcttttgcg ggcgtattga tcgagacggc
    11581 catgaatgta actttcccaa ctcttatcag acagtttgat ttaacgactg cacaagtcca
    11641 atgggtaaca acgatttatc ttttgatgat ttcgatcatt gttccgctgt ctacttattt
    11701 gaatcgcaat tttagtctca aaaaactctt tttagcttca aatctgcttt tcttggcagg
    11761 tataatgatc gatttcttct ctcctacctt catggtccta ttgtttggtc gattgctcca
    11821 aggtgcagcg acaggtatcg ctcttccgtt gatgttccat attatcttga catttgcccc
    11881 cctcaatcga cgaggcgcga tgatgggtgt cggtactttg acaacggcca ttgctccagc
    11941 aattggcccc acttatggag gcattatgac ttcacatttt acatggaatc atatcttcct
    12001 gtttcttgtg cccgttttgt ttctttcttt gattatcggc tggtttgcta ttcccgagat
    12061 ggcagtacaa aaaagtggtt atttggattg gataagcgtt ttaggaattt gtcttttgtt
    12121 tagtggaagt ctaacatttt tgagtacgtt gggaacagtt tccagctgga ttgctttaat
    12181 catcggcggt attggctggt tcctttttta ctatcgaagt aaaaaagtgg agcatccact
    12241 gatccgactg tctattcttt caaataaaac attccgcttg tttttgattg gcttcttagt
    12301 ttatcagttt ttattacttg gtgtatcttt tgtcttgccg aatttccttc agatcgttca
    12361 aggaagtagt ccttttgtcg ctggattagc gatgcttccc ggcgcagcgg ttggtgcttt
    12421 gctttctcct ttttccggga aaatgctgga tcaatatggt ccgaagaagc caatttttgc
    12481 tgggctgatt ctttctttga ttggttggct agcattattc ctactcatag gacacgcttc
    12541 agtgggtgta ttgattgctt gtcatgtgtt ttatatgatc ggtatcggat tatcttacag
    12601 caatatgatg accaccggaa tgaatgcact gaatgaagaa ctacaaggag acgggaacgc
    12661 aatgttcaat accttgcagc agttttctgg cgctgtggct acttcattag tagcggtcat
    12721 tatcaattac gtccagcatc atacttccca taactatgaa gtgtctacta cattaggatc
    12781 aaaagcagca ttaggcgtct tgttgctgtt gcttctcgta agctttgctc gattcgccta
    12841 ttatctgttc tttgctaaaa aagcgtagat tccatatacg gcaggtgttg catctgccgt
    12901 ttttttgtgt gaaaatggtt gtttgtaaaa ggaggctttt ttatggaaaa aattgccatt
    12961 atcggtggcg ggatcattgg tatgacccta gccagttact tagatacatc aaaattcaat
    13021 gttgctttat ttgatgaagg gacaggacag gcaactaaag ctagcgctgg gattatctcc
    13081 ccttggttgt cgaaacgcag aaacaaacaa tggtatcgtc tggctaaaga cggcgctgct
    13141 tttttcccta aacttataaa agatttccaa cttgatcaaa cgatttacgc acaatcaggg
    13201 acacttttgc ttcgacctga aaaagattta gctgaattgg ctgttcttgc cgagaaacga
    13261 aaagaagaag cgccagaaat tggaaacatc gaatggcttt cacctgaaca gacatctcaa
    13321 gcacttccgt tattgaaacc agcagtttca ctgcgtatca gtggtggtgg tcgtctggat
    13381 ggaaaagcat atttagaaca tcttggtcag cgtttagcac aaaaacaaat ggagcagatc
    13441 caggcaaaag tcactttgca taagaagagc gattcttggc tcatcaaggg accgtttgga
    13501 gaatacacag ctgatcgtgt aattttgaca cctggcccgg cacttaagcc tttattacaa
    13561 gaattaggct atgctgcaga tatacgtccg caaaaagggc agctcttagc atttcagaca
    13621 tcttataaga tgagtcaaga ctggcctgtt gctatgcttg acggagaagc tgatttcatt
    13681 cctttcatgg atggaaagat ccttttaggt gctacccatg aaaacgatca aggctgggat
    13741 ttggctccta ctagcgaagc ttataaggga ttgactaaga gtacagaaca gttcttgact
    13801 gatccagatc agataaaaaa ctggccatac gagttccgtg taggtacccg tgcttatacg
    13861 tcagattttt ccccattttt cggcgtactg ccagatgatc caagcttact ggctgctagc
    13921 ggtctaggct cttctggctt gaccacaggt ccttatatcg gctatctatt agccaacttc
    13981 ttaaatactg gtcattggcc tacggaagat tatcaaaagg acatctccac ctatattacg
    14041 aaaaatccat catagaaaaa cagctttttc aagtaaggat cccgagcgat attgcgcatg
    14101 gattacttct tgaaaaagct gttattttag ttcaatttct gaatcaaatt ctccaaactt
    14161 tcttttgctt catctggcaa gagatctttt cctatctgag cttcaatgaa tcgtaaacga
    14221 atatcaagtc gttgtttcac cagattttta taggacgtat cctcaaaaga aacaggaaaa
    14281 tctggtatag gtaaatagtg gatgtcttca aatggaccaa acgacttgaa ttctgccgtt
    14341 tgttgcacga ttctttcaac gattgacaat gtcgtttcag gtttgatttt tttatcatcg
    14401 aaatatccag tattcaggac atagcaggct gtttgctgtt tcaaaaacaa ctctcgaaaa
    14461 gcttgatagt cttccctaag aggatagaca cggaaaggat tagcaaatgg ttcaatgact
    14521 agctcatcta gctgtctttt tgtagtgata ttttccgcgt ctgatcgttt tgttgctaat
    14581 gttgcaccaa aagacgctgc taaaactggg tcattgatct tgataattgg cggaagcgaa
    14641 tcatctttca tgatccaaaa aacagcatcg atcttttcgc taagatgatc gactcggtcg
    14701 ggtgtcgcat aacgtgattt gactgtccgc ccatttccgt ttcgtatatc tcctgttact
    14761 aggacttttt ctcctttact tgtacatgtc acgcccacat tctgacaagt aaggaaagaa
    14821 gaaatggccg gatcatcaga cggatagtct tgtgttttat caaagtaaga aggttccaag
    14881 gcagtagcaa aaccattttt tcgagaaata acgaaagcat cgtcatgcaa gatcgaaaca
    14941 gagtgacctt ccgtatgttt tgctaaggta atcgttgatt ttccagaacc ggacaaccca
    15001 aatacagcca tcgtataggt ctggtcatta ctagcatatt gtttcatccc accgtggcag
    15061 gcaataaagc cattgcgatt tcccaatgcc caagcaagcg tcaaagtcgc tttttttaat
    15121 tctccaaagt aacgtaatcc tagcacagcc gctgtattat ggagagcatc aaacaaaatg
    15181 agtccatttg gaaatgtttc atgtgtccat tcgggatcac aaaagatata aagatctccc
    15241 tcatcaaagg aaacagactt ttgataagtc tctaagatct tcgaattcgc tggctgaaaa
    15301 ttcagcaaat aagaatacaa attgttctca aatccttctg gaatcagcaa atgactttgc
    15361 acagaaaatt cttcagatag gccaacgatt acttttgtat ggtaaaactg gcgcttgcga
    15421 ctttgataca cagcttctct taaaattttc tcgtatttgc tttgttcctt gtctaagtcc
    15481 tcaaagatcc gccgagcact tgctgttctt cccacaatgc ttccatcatt gaatactagt
    15541 gtcctaacat cagctggtaa atctagttct tcagcatgtg agattgttaa atctgtgatg
    15601 atcgttcctg gactcccttt tgctagttga taagctgtct tcctatcaaa aacttcatga
    15661 acattattac cgtaaaatgt cgtttctaca atcgatcgaa tactggataa cagtggattt
    15721 ccacttgtga tttcgtttaa ttcgagactc tcttttgtac tcatggctcc tcctcattcc
    15781 ctaaacaaaa aaacgttttc tttattatac attattcgag tttttatttg tactgctgcg
    15841 ctgtgggaag caaacgagtt atttttcaca caaaaaaacc gagaacttga ataaacaagt
    15901 ttctcggttt catcattttc cttttatcgg cttagtacca gccgtttgct aaccagaatg
    15961 ttttagcagc atcccatgaa ccataacgag atgttacata ttgttctgct acacgttctt
    16021 gattggcagc tgaatagtcg ccgtttaagt atgaagcatc taattgataa cggccgatgt
    16081 aacgtccgtt agtagctgtg tatgaaccgc ctgattcttt ttgtgcgatc cattcttttg
    16141 cagagcttga agttggcgct gttgcagcag ctggggcagc aggagctact tcaactgttt
    16201 caacaggtgc aacgtatgta tgttcttgcg ttgctgtttc agttgtagat gctgtatttt
    16261 ctgttgtttt gttttctgtt gttgctgaag aatcatttga agttgggatt gttaattgtt
    16321 caccaacata aatgcggttg atgtttgcga tcgaattttt ttcagcaatt gcatcgatca
    16381 ttgagttgtc tcctgcaaat ttttgtgaga tcttagataa tgaatcacct gattttactg
    16441 tataaacttc atcagcgtga gcatttgtag ttcctacaaa cattgcagta gcaccagcag
    16501 caaaagttgt acctaaaaca attttcttaa atgaattcat attaaactcc tttttttctc
    16561 cgttttttat tctttcgacg ctattaactt tatcatttag aaatatttca taggtaaaag
    16621 aaacatgaca tttaatgaca aaataacgaa ttatttaata tttgtaacat ttaaacaaat
    16681 atttttttga tacaaaacca taaaagcctt gttgtataag caaagtaatc gtttttctat
    16741 gtttttttat ttttgaatga aaaacgcaga ttctgtaaca ttcactgcaa taatccataa
    16801 aaaaaagcaa aaaaattttt gatttttatc aaattctctt aaaaaaatgt aaaaaataca
    16861 aaaaaaccag taattgttac aacaattact ggacaaaaac tttgaataat gttaactatt
    16921 tttttatttt aactttctcc gcaataattt ctgggcatgt tccaattcgt ttataacgac
    16981 ttcttctgtt tctttagcta atatttcatc taatacatca agccattttt ccggttcttt
    17041 tgttcctaga cgtccaatag cccaagctgc tgttcctctg atgacagggc ggacatctgt
    17101 taaacattct gaaatctcag gcaatgccgt tcgatcacct agattagcta aagcaatcaa
    17161 tgcgtttctc tgcaaaggtt tcttcccacg ccatgaacca gctaaatgcc caaattgctg
    17221 tttgaagtct ttattagaca tcgaaagcat tggctttaat tttggatata tttcgtctac
    17281 ttttggttcc atctcttcat gaaaatgaaa atcttttcct tgattgtaag ggcagactaa
    17341 ctggcagata tcacatccat aaatgacatt tcgcattttt ttacgatatt cttccggcat
    17401 catccctttt gtctgagttt gataagacaa acatcgctgg gcattcattc ttccgtcacc
    17461 aagcaatgct tttgtcggac aagcagtcac gcagcgcata cagtcaccgc aaccaaattc
    17521 tccaggttta tcaggctcaa atacaatatt agtaacgatc tcaccaagat agacaaatga
    17581 accgaactct tcagtgatca acaatccgtt tcgtccaata aatcctaaac cagctcgctg
    17641 tgctacagcg acatcgatca gttctccagt atctacttgc ggagctagac gccattcctc
    17701 ttctttttgc catttttctg ctcttgtttg gatgaattcg atcaatcggt tcaaacggtc
    17761 tctgagtata tcatggtaat cgatccccca agaagcacga gcaaactgcc cgcgtttttc
    17821 atccctaggc acttcttcat ggatcctagt aggatacgca agtgcaatgg aaatgatcga
    17881 tttcggctga tcaaatgtca tttctggata aagacgctca tcgatatttg gatgttcaaa
    17941 gccagaagta tggccagctg ctttttgttc ttccaacgat tcttttaatg aatcaaaagg
    18001 ttccgccgtg gtgaacccga ttttgtcaat tcctaatcgt ttgctttctt gtatgatttc
    18061 ttcttttaat gtcatggtct tcctcgcttg ctgttaacgg ctgtataacc cataatatag
    18121 tttttctttt ttcagctgga caaactggat ctgctgatcg gcaatcttct tttcttccat
    18181 ccattttttt cttgcagcaa atacttccca ataatttgtt gaaattaatt ttcttttgtt
    18241 atctaatgca ttaaaaaaat tcaatgaaac tggttttgta cttaacagtt catggagcct
    18301 tacctcttcc catggcgaaa actcagacag atcgcgggaa tacaatactt cttcatagag
    18361 atttttttgc tgtgtgtacg tgaatgtttg cgggattttc ccaggcctag caatttctac
    18421 tagacgatta taaaacatat tcattaattt gctgttggca ataaattgac ttttataata
    18481 ggccgactgg atctttttga ttactccttc tgctttgatg actgaaaata atgcaggcca
    18541 tgctttgacg gttatttcgt cgttttgttt aactaatacg ccaggtgtga agccgactgg
    18601 agaaaggaac acaaaataac cgataccggt attttcatct aaaggctgaa attcatcaaa
    18661 caaccatttg cctatgtaca gctcttcatc tggttctgtt gtctcatttt gatttgctat
    18721 gaataattta gctaattctg cttcaagaaa ttgaaggtct tgatccttgt cggtattttc
    18781 ctgctggctg atcaatcgaa agacttcttc tttaatcgta tatttatctt tacgtgtaaa
    18841 attcatagcc acaccttcct tccttactct aactataacg gaatttcttc aaaaaaggta
    18901 tctgtacgac gaaaaacagc ataatttttt ttcatatctc ttataaaaaa tgcaaggtct
    18961 gctcctcaag ctagaccttg cacttttcag ctttcttttg tttgtgacaa accttcatgg
    19021 atcgtttcaa tattccattt catcatctga tagtaagaat ctccttgttc tccttctttt
    19081 gctatggaat cagtgaacag tttatcatag attttcaaac ccgtttcttt tgctacccgt
    19141 tccatgcttc ttgagtctac actggtttcc acgaataaaa ccggtacttc ttttgctctt
    19201 atctgatcaa tgatcgcttt catttgatca ggcgtacctt gactttctgt attgatctcc
    19261 catatataag ctgctggcaa atcatatgct cgtgaaaaat acttgaatgc cccttcactt
    19321 gttactaata attttttgtt ctcttcgata gaagcaaaac tttccttcgc ttgtgtatct
    19381 aattctttta gtttttccac atatgcttct gcattttttt tatagagtgt cgcattttct
    19441 gcatcttttt cagagaatat acgtgcgatt tcctccacat attttattcc gttagatagg
    19501 tctagccaag catggggatc tgcttttgta tgttcttcac cgctagttaa ataaagaggt
    19561 tctacatttt tgctaactgc aaaataatct tttccttctt cttttttagc cgtttccatc
    19621 aagttatcga accagctgtt acctgtttca agattcaaac cgttgtataa aataacatct
    19681 gcatcgcttg cctttttgat gtcttctggt agtacttcat attcatgcgg atctgttccg
    19741 actggtacga tactgtggat atctatttga tctgttccga cctcttttgc catgtccgcc
    19801 aagatcgaat tggtagccac gactgacaac ttttctttac ttccttcatc cgcttggtca
    19861 gaagcctgct ttccgcaacc ggctaatacc aagaaactaa ctgccaagat taaaaagagt
    19921 gatttttttg ttttcatcta tctgcttcct ttctgaaata aaattccttt tgttggagaa
    19981 aataaaaaag caaggataaa aaatgcggta catgctaaca cgatcgtagc tcctgatggc
    20041 caattgtaac tataactgaa aaacacaccg acaactgcac ttagcatacc gattcctgca
    20101 gctgtaatga tcattttcag taaatggttc gttagcaagt aagccgtggc ggctggtgtg
    20161 atcaacatgg caatcaccaa gattgttcct actgtctgta aactgactac agccactaat
    20221 gtcaaaaaga acatcaaaag ataatggatc agcgatgtgt tcagcccata agcttttgcc
    20281 attgtcggat cgaatgatgt gatcttcaat tctttataaa agaaaaagac aaatatcaag
    20341 acgattccac taacgagtgc tgtcagcaac aaatcgcttt ccctaacagc taagacattc
    20401 ccaaataaaa tatgatacaa atctgtcgca ctctgggcat atgaaatcaa gataatccct
    20461 aatgcaaaaa aggagctaaa gacaattcca atcgctgtat catttttcaa tcggctccgc
    20521 tgagtcacga aaccaatcac tgctgctgtt agcatcccaa aagcagtggc tccaaagatg
    20581 taactaaaac caaacatata agaaatggct acacctggaa gaactgcgtg agagatagcg
    20641 tctcccatca aagacatccc tcgtaaaata ataaaagaac cgatgactcc agaagcaagt
    20701 cctacaagca tggaagtgac caaagcgtat tgcaggaatt gataattcat taatccatca
    20761 ataaaggatt ggatcatttt ttctctcctc cttttactaa atgtctgatg atctcaccat
    20821 aggccaattg aaggttcttc gatgtaaaga cttcttgtac tggaccggaa gcgatcagct
    20881 gtttatttaa aagaataacc tcatcgaaat attcttctac tttatgaaga tcatgatgga
    20941 cgatcaaaat cgtttttcct gaattcttca attcctgcaa gatgtcaaag atctttcgtt
    21001 cacttaacgc atcaatccct acgaatggtt catctaaaaa gatccattct gctccttggg
    21061 ctagagctct tgcaataaaa actctctgaa gctgtccacc cgatagttcg ctgatctgtc
    21121 ttttggcata ttcttccatc cctacttttt tcaaagcttg tcttgcacgt tctttttctt
    21181 ttttcccagg tctttgtcca attcgtaaag atggatatgt tcctaaaagt acaacgccta
    21241 atacatcaat tggaaaggaa agatccaatt cacttcgctg ttccacgtag gctatttttt
    21301 tacggactga gtttaccgac tgtccagaaa aggtgacttt accagtagta gctggtatca
    21361 actctagcaa agatttcata aatgttgatt ttcctgcacc gtttggtccg ataataccgg
    21421 taattttttg tggatttatc gtcaagttga tagttttcaa aacagttttc ccttgataag
    21481 cggctgaaag gtcttgaatt acaatggccg tacgttccaa atcttacact cctttttagg
    21541 tttacctaac tttttattta aatatagttt aactaaaatg gaaagcattt tcaagtagaa
    21601 tgatgaaaaa gtttttttcg aattttcctc gcattttatg aaaattttct gtagaatcac
    21661 atcaagagtt caataaggct aacctaataa tgaaaaacat gtgttgaaac gtttgattat
    21721 tttttcttgt tgactcaaca acgaaaggag tttttgtatg gaagaagaaa agttaactcg
    21781 aagtcttagt gcccgtcata tccaaatgat cgcactaggt ggaacgatcg gtgtcggtct
    21841 gtttatgggt gcctcctcaa ccatacgttg gacagggccc tcagtgatgg gagcctatgc
    21901 gattgcagga ttctttttgt atttgattat gcgtgcttta ggcgaaatgc tttacgttga
    21961 tccttcgact ggttcttttg caaattacgc gagcgagtac atccatcctg tggctggcta
    22021 cttgaccgct tggagtaata tttttcaata tattgtcgta ggaataagtg aagtgattgc
    22081 tgtaggatct tatatgaatt attggtggcc tgatttgccg gcaattattc ccggaatcat
    22141 tgtcgtcttg tttcttatgc tggcaaatct tatttctgtc aaggcgtttg gcgaattata
    22201 attttggttt tcgatcatca aagtcataac gatcattttg atgatcattg caggtcttgg
    22261 ggtaatctta tttggatttg gtaatcatgg tcaggcagta gggatttcaa atctttggaa
    22321 aaatggtgga ttcttcactg gaggcgtcaa aggatttttc tttgcattat cgatcgttgt
    22381 tgcttcctat caaggaatcg aactgatcgg aatgactgct ggtgaagcag agaatcctaa
    22441 aaagacgatc attgaagctg tccagtccac tatcggtcga atcttgattt tttatattgg
    22501 tgctattttt atcattgtga gtatctatcc gtggaatcaa ttgagtgaga ttggttcacc
    22561 ttttgtacaa actttttcta aagtcggcat tacatttgct gcaggactga ttaattttgt
    22621 cgtgattaca gcggcattat caggttgcaa ttcagggatt ttcagcgcaa gtcgtatggt
    22681 ctatacactt gccataaatg gaaagatgtc taaaaaattt ctgaaactat ctcgtcacgg
    22741 tgcgcctttt tatcctgtcg tagcaatctc aggtggaatc ttaattggtc tgatcttaaa
    22801 ttatcttcta ccaatgttca tcaaccagtc agaaaatatt ttcgttttcg tatacagctc
    22861 aagtattttg cctggtatgg ttccttgggt agtgattttg atcagcgaga ttcgcttcaa
    22921 aaagaagcac gcagataaaa tgcatgatca tccttttaaa atgccactat ctccttatac
    22981 gaattatgtg acacttgctt ttttagctat cgtattgatt ttcatgttta tcaatcctga
    23041 aacgagaatc tcattgatta ttggactcgt tttcttgctt tacatgacga tccattactt
    23101 tgtacgcgaa aaaagaaccg gaaaataaaa aaagaacgaa gcttcacctt agtggaagct
    23161 tcgttctttt ttattgcttt tatcaattca attttagcgt ctcaccggga gtcaggaaat
    23221 aattctccat gctcatccca ttcagcgaca agatcgtttc tactggtacg ccagttcgtt
    23281 cggctatttg atttggacct tctccttcca aaactacggt tgtcgcagcc tgtgaagtcg
    23341 cgctgttggt attagtttca gaggaatctg ttgtgtcttg tgttgttcga gcttgcattt
    23401 cagaagcttc taccgactct gctgtctcag aatcagaaga tgttgtgtct tgtgtgcttg
    23461 ttgactctgc ttgaagagag gcgctagtct gcaaataaat atcggaaatc ttagcgacat
    23521 gattcgtata attagccgat aattgattga tcaaagtatc taagtctaca ccgtctttat
    23581 tttctgctgc ctgatacgct gcacgtaatt ttctgatccc ttcgtcggag attgcttgaa
    23641 gctcacgtgc tttttggtta gcaactgctg ataaaccagc tattccctct tgatttccct
    23701 gaatttctgt ctggtattct tcaatcaatg caggcgtctt ttcttcgatc tttttcgaat
    23761 aatcatttac gattgcttga agttgctctg gcaaaccatt tgctgttttt tcttcagaag
    23821 tttgtgtctc ttttgtttta gttgatgact cacttgtttg tttcgtctct gttttctttg
    23881 tcgttgtttc cgttatggtc gtacttttcg cttctgacga attttttcca tgaaaatata
    23941 gacccgcaac tcctcctgct atgatcaaaa acacggcaac tgctgcccca atcatgatca
    24001 tccgcttacg agctgcctgt ttttgctgtc ttcttcgggt catccgaaca ttttctcccc
    24061 actcattttc atcatacatt tttttcacca ccaattttta tgtataatag cgttatcaaa
    24121 cgcttcatat tcttattgta gcaaataatt gtcgctgtgc acatttttat ctttgttatt
    24181 tataagaaaa tttcaccagt tgagatgatt ccaagattgt ccgtcgattt ctccttgcag
    24241 ctgcattgtt cgttcgtcta tctcagccat cagtttcttt atttcatata agagcgcacg
    24301 gtcttgatat tctgattttt cgcttaattc atctaattgt tggatcagcc aatcatttgt
    24361 cataatgaag ttcctttcat ttcttgcagt gtaaaggtca agtcttcgat ctgctctttt
    24421 gcctcagtca gtgcttctac gatatatgct tgtttttcag attcttcttc ctgcattttc
    24481 tgattttcct gtactctttg aataaaccag tcaatccgct gagtcagcga tggtttgcct
    24541 tccaatgaga gatactgctg ataagcaatt agcttctccc aacgtttttc ctgggataaa
    24601 tacataaatt gtgctaaaac gaatggcgga agataggtca tatggaattt atttgcgatt
    24661 cgctgatacg gcctcaaaaa ttcggaaatc gtatattctt cttttcctcc agcttggtat
    24721 tctttttccg ccacacctgt tgtcaatacg attcctagtt ctttcccttt taatacatgt
    24781 gctgctcgtt ccaagacatt atcttgccaa atttttaaat gagcaggaga actataccag
    24841 taaaacggaa actggaaaat gatccgatca tgctgggcca agagctgtag ttcagtctct
    24901 atatctattt ttccgtctgg ataacttgat tccaaatgat gccaagtagc tggtaaacca
    24961 gcagaagctt ctttgaaaaa ttgctgattt aaagattctt cgatcgttgg atggctaatg
    25021 atgataagtg tacgcatccc ttttcctcct ttttagtctt cgctttacag tgtagcataa
    25081 ccgccacaag tttcttttgc cgatgcttgt cattttaacc agactaatca ggttgtccaa
    25141 gaaactgcgg tttgtttttc caactgtttt ttcaaggtat ccaaagcaat attcttaaaa
    25201 ttttcgtttt tcatacgttt acgatagttc gtagccgttt ctccggtact ctttttgaac
    25261 attcggctaa atacgactag actattgaac cctacttgat aggcaatact ttccacggat
    25321 tcatccgtca gagaaagaag aaacgcccct cgattgatcc gtaccccgat caaatattcc
    25381 ttgatactgg tacccatatg atttttgaat actcgcgaca aatggctccg attgaccgct
    25441 aaatgctggg cgatttcctc aacagacaat ttttcagcat aatgtgcctc gatgtatttg
    25501 actgtttcaa cagctaaaga ggaatgaacc ttttgtacac caccgctgac ctttccgcca
    25561 tcttttaaaa ggactgataa aaaacggtag gttaatgctg ttaactgtaa ttcattttcc
    25621 aaggtttctt ccgtatcttt catgcattct aaaataatgt cgatatattt ttgtatgtca
    25681 gaagagacca tcgtgtattg gtcttctctg aaaagcgact gccgaatgat ttcttctgca
    25741 gcactcccac caaatgaaag ccagcaatac atccacggat cttctccatc tgataagtaa
    25801 aacgtcgagt ctcctggacg aatcaagaac agatcacctt ttttcaattg gaattgttga
    25861 tttttcacat gataagatcc tttgccttcc atcacgacat gcaggatgta atcattgcga
    25921 atagcaggac caaaagaatg aaacggcatc gttttagaga aaccacaaaa atcaaaatac
    25981 aattcttttt ctacttgttg atgttccttt tttaaaaaaa tcgattgctc cacgtctatc
    26041 cctccttact cctttagtat aatgcaacaa aaagttaaat aaaagtcaca gaaatatatt
    26101 aaaaaggaag cgatttcttg ttaagtttaa gtcattaaaa gatctttgtt attcgttgta
    26161 accggtttac ttagtattat atattgaaca ggagaggaat acagattatg aaaagcaaaa
    26221 tgatccaacg tgtgtcctac gctttaggcg cttttggaca cgacacattc tatgttacat
    26281 taagcactta ttttatggta ttcgtgacaa gccagatgtt cgcaggaaca gataaggcaa
    26341 cgaatgcaaa aatgattgct acagttacaa gcttagttgt aggtatccgc ttagttgaaa
    26401 ttatttttga tcctttgatt ggtggcatca tcgataatac tcgtacaaaa tacggtaaat
    26461 tcaaaccatg gttagttatc ggcggcgttg ttagttccgt actcttggta gcaatcttta
    26521 ccaatttctt tggcttagct actcataata cgactttatt tatcatatta tttgcaatcg
    26581 ttttcatctt attggatagt ttttattcat ttaaggatat cgctttttgg tcaatgattc
    26641 cagctttgag tacggaaaca aaggaacgtg aaaaatttgc tacgtttgct cgtttcggct
    26701 cttctctagg tgcaaatggt actactctag tcgttgtccc tatcgttact ttctttacct
    26761 atcttgttac tcataaacat attgaaggcg cttcaggctg gttctggttc ggtgtgattg
    26821 ctgctgttat ttcaggcggt actgcgatta tcactgcctt gggcacaaaa gaagtcgata
    26881 ctgcgatccg tcagcaaaat gaaaaagctg ggatcaaaga tgtgttcaaa gcagttgctc
    26941 aaaatgatca gttgatgtgg cttgcccttg cttatatcgc ttatgcgatt gccaatgcag
    27001 caacaactgc cgtattattc tacttcttca aatatgtact tggccaacca actgaatttt
    27061 ggatcgttgg tctagttgct gccttacttg gtttagtagc tgttccacta ttcccaatgc
    27121 ttacacgcgt catctctcgt cgctacgttt accttggagg gatcgcaatg atgatttctt
    27181 cttacttttt ctttacgatc gcaggttcaa gtttgccaat cgttatcatc gggctagtat
    27241 tgttctactt ccctcaacaa ttgattttct tatccgcttt gatgacgatc acagactctg
    27301 ttgaatatgg tcaatggaaa aatggtatcc gtaacgaagc tgttactcta tcaattcgcc
    27361 ctttactaga taaaatcgct ggtgctttgt ctaacgggat cgtagggttt gtcgctatcg
    27421 cttctgggat gactggtaat gctactgctg ctgatatcac tgctcatggc gtaacgactt
    27481 tcaaagctta tgcattctat gctcctgctg ctttgatgat tttctccgct attatttttg
    27541 cttggaagat tacattgaca gagaaaaaac atgcacaaat cgttgagaaa ttggaaaaca
    27601 aattggctcc agctgataca atggaagatt aacttcacga tgcagtagtt ccttcccatt
    27661 aagaaaggat cttgaaaatg aagattacag aaaaagattt tggccaaggt tatcacttga
    27721 taaccttgga gaacaaaaac aagctagcac tttctatctc tgatttaggt gctagaatcg
    27781 tcagtttaaa atcaaatgat cgagaattag ttttgggatt tgacaccgct gaagaatata
    27841 tcgaaaaaga tccgtatatc ggtgcttcta tcggtcgcac cgcagggaga atcgaaaatg
    27901 gccgcttttc tctcaatgga aaaacttacc aattagccac agatccaaaa actggacata
    27961 atctgcatgg tggtgctcct ggatttgaat taaaaaaatg gtcttatgtc attttgaatg
    28021 gcgaaaatga agcttctgtc atttttacta ctacaagtcc cgacggagaa catggttttc
    28081 caggtacaat ggatgtggaa atccgctata ctttgacaaa agataatatc tggcgagtga
    28141 cctctcgcgg caccagtgac caagatactt tattcaatcc gacaaatcat gtttacttca
    28201 acttgacggg agatgcttct cagtcaatcg atcaacatga gctttggctc aatagcgaag
    28261 cttatgctcc tttgcgaaca gatagtattc ctataggggt aaaagaaaat gctgcaggaa
    28321 gtgctttcga ttttcaaata cctaaaaaat tagcgtccgt ttttgctagt gatttggatc
    28381 aaaaaaatct tgttgacgga atcgatcatc catttttctt aaaagaaacc ggcttgggta
    28441 aagaagccgc tcgcttgact agccccgata aaagaatcca agtagatatt gctacagatg
    28501 cttctagtgt ggttattttc actgcaaatt tcggcacaga aacaccagaa atgcgcaacc
    28561 gaaaactggc acatcacggt ggcatcacat ttgagactca aacagctcca ggtgcagagc
    28621 gcttctcagc atttggttcg attcatttaa aagccggatc agtatttgaa acagtaacag
    28681 aattcaaaat caaaacaaga aaggaataac tcatcatgga aatcaaaaga agcttaaaca
    28741 caaaatttgc cgaaacattc ggacctaaaa aaactacaca atacttctca ccaggacgca
    28801 tcaatttgat tggtgaacac acagattaca atggaggcca tgtcttcccc gcttccatca
    28861 cttatggaac gcaaggtgta gcagcacctc gagacgataa taaaatatta gtttattcca
    28921 caaactttga cgatatcggt gtcattagtt ttactttaga tgagctagaa tatgataaaa
    28981 aagcaaactg ggcaaattac gtaaaaggaa tggtccttaa attaaaagaa gctggacact
    29041 caatcgatca tgggtttgag ttattagtgg aaggaacaat ccctaatggt gcaggacttt
    29101 ccagtagcgc ttcattagaa ttattagtag gtgttgtatt agaagatctg tttgatttaa
    29161 aaacagatcg cttggaacta gtccaaacag gtaaaaaagt agaaaatgaa ttcatcggtg
    29221 tcaattcagg tatcatggat cagtttgcca tcggcttcgg tgagctagat catgcaatct
    29281 tattagatac aaatacgctg aaatacgaaa tggttccagt gaaactagat ggttatgcaa
    29341 tcgtcatcat gaatacgaat aagcggcggg aattggcaga ttcaaaatac aatgaacgcc
    29401 gtagcgaatg cgaagaagcc ttggcacgtt tgcaaaaaac tttgcctatc tcttctttag
    29461 gagacttaga tgaagaagaa tttgaatcaa ctattgacca aatcggcgat gatacattga
    29521 tacgcagagc tcgccatgcc gtttctgaaa atcagcggac tttgaaggca aaagctgaat
    29581 tagaagctgg gaacttagaa gcatttggtc aactgttaaa tgattctcac cactctcttc
    29641 gctatgatta tgaagtaact gggatcgaat tagatacact agtagatgct gctcaaaaac
    29701 aagaaggtgt cttaggtgca cgaatgacag gagctggatt tggtggctgt gcgattgctc
    29761 ttgtcaaaga agaaaatata cctgccttca aaaacaatgt ctatgatgaa tacatgaaag
    29821 ttgtcggcta tgctccggaa ttttatgttg cacacattgg aaatgggaca acaaagatcg
    29881 atccagaagc tgttcatgtt tgataaaaaa atcaacgatc tcagctaaaa acaaatagat
    29941 aaaaataacc tctcagcaat ttccaaatgt gagccttttg ctcgtatttg aaaattgctg
    30001 ttttttattg acacggaaag agaacgtgtg ttctaattgt gttgaagagg tgattgttat
    30061 gtgggcgaat caaaatccgg tatttgttta tgaaaaagaa ccttcaagag atattttatg
    30121 tattgactgc aaatcttttt acgcctccgt agagtgcgtt gaaaaggatc ttgatcccct
    30181 tacaactaaa ttagtagtca tgtcctatcc gtccgattcg acagaaacac ggggtagcgg
    30241 attaatcttg gcttccagtc ctgcagcaaa aaaagcttac ggcatcacca atatcagccg
    30301 tgccagagat cttcccttcc cctatccaag tgatttatat attgttgccc caaggatggc
    30361 ctattatatg gaaaagaaca gagaaatcaa ttctatctat aaaaaatatg cagacgaagc
    30421 gaaccatcat gtctattccg tcgatgaaag cttccttgat gtaacaaata gcatggcact
    30481 ctttggtaaa acaaatgcgt acgacatggc taaactgatc cataaagatg tgtttgagca
    30541 gaccggaatc tacacgacta taggaattgg cgataacccg ctacttgcta aactagcctt
    30601 agacaatggc tcaaaagacg gaaagcaaat gtttgctgaa tggcgttatg aagatgtacc
    30661 agaaaagtta tggaaaatct cagatatcac tgacttttgg ggaatcggca aacgaacagc
    30721 aaaacgtctg aaacaaatgg gtatacattc tgtttatgat ttagctcacg cggattatta
    30781 tcacttgaaa agcaagctag gggtcatcgg tactcagctt tatgcccatg cttggggcat
    30841 cgatcgaagt tttttgggac aagaatatac accaaaatca aaaagtatcg gaaatagtca
    30901 aatcctagat agagattata caagacgaga agaaatcgag atcgttatca aagaaatggc
    30961 cgaccaagtc ggcactcgct tgagacgatc tgcagcaaaa acacaagtag tcagcttatg
    31021 ggtaggatac tctttaggct atcttgatcc aaatggcaag accgggtttc accagcaaat
    31081 gaaaatcgaa gcgacaaatg ctagcagaga tcttgcagat gctttattga ccattttcca
    31141 ccagcattac cactaccagg atattcggcg tgtaggcgtg aactgttccg acctcgtata
    31201 cgcgacaggt ttacagctta acctttttga agatcctgaa aagcagataa atgaagcgaa
    31261 agttgatttt gttgtcgata cgattagaaa aaaatacggc tttcaatcaa tcatccatgc
    31321 gcatagtctc ttgcaaggag gacgcgccat cgcacgtagt tctctcgttg gcgggcatgc
    31381 aggtggtatg agtggattag aaggtggaaa agatgagacg gacagcaaaa aaattcattg
    31441 actataacga gtatcgagat cggccatttg gattaaaatg ggggactgct tttgcgatgg
    31501 aagaactagt caacggtatc aaaaaaatga agaagaagca cgcaaacagc ctcttcctaa
    31561 acaacaaatg acattgcaag aaatcgatag tatactgaca gaagcctttt tatctcgtaa
    31621 agcagtaatc attcagctca atttaaaaga tgaatttgga agactcttgg atgaggtcga
    31681 agggcacttc attggtgaag cctatgaaga ttactttatg attgaccatc agccgatatt
    31741 gtgggaagac gtacggtata ttgagttaaa ggaaacaaaa aaatggtttg tgacatgaga
    31801 ggttgtgaca gaagtgatca acttcaaaaa ataagaaagg atttttcgaa aattgcttct
    31861 taaatttttg tggaattttg gcttattttt cgaagaagca acttctggaa caacgtatat
    31921 tagatatcag aggttgtgaa aaagtcgctt agttttgagt aacaagccaa ggcgctgatt
    31981 tcacaacctc tgtctatcta tccatctatt cggtaagatt catgcatgac gtcttcttta
    32041 tttagtatgt agagcccttt ttcttctgac cattcaacat aaatcagctg ttttacatct
    32101 gcatagcctt ctttcttcaa gttctccata agccatgctt cagtcaattg attggactga
    32161 agcactttat gctgaatttg cccttcatct acaagcagga tcgataaagc tttgtcttca
    32221 tctgattttt tcaatacact catttgaccg gcattctcta ggataacatg tttggcattt
    32281 tcaagaaaaa agcattcttg ctgtcttaag attgctcgca actgctccat ctcgatatgg
    32341 ttatttgtca actctgtcat gttgatgacg ccgtctttga ttagaacaga tggctcgcct
    32401 ttgacccaac gattgacctt ttcatttttt tggacgatac gttcgatacc ataaatcatt
    32461 actgcccaaa gcgcaatggc aaataggaca tgccctacat ggacattgtc atcataggtt
    32521 gattcttcta agatcccacc taaaacaagc gtatagacta aatcaaacgg tgtgatttct
    32581 gacatggatt tcttcccaag caaacgtacc actaataata aaccgatcaa cccgaacacc
    32641 agtttcattg taattgaaaa aatcattttt tctcccccta actatctgtt aattaaatta
    32701 tatatgcttt ctcacgaaca cgcatggaat atacaaggaa gaaatgtatc cttttactaa
    32761 aaaaaggact gtgacactgt agtgaccccc aaaagttaga cttttttgga gtggagaaat
    32821 ccactccttt tttttatgct ctaaaatgat atttttacac aaccgttacg gttgttttac
    32881 gaaattggac gagactttgc cagtttaatt tctgttttat ccgttcatta ttgtagtaat
    32941 agatatagct atcgatggct gattttaatt cctcgaaaca gttataaact ttcccgtgaa
    33001 aaatctcttg ttttaataag ccaaaaaaat tctccataag tgaattatct aagcagttcc
    33061 ctttccgaga catgctttga aagattttgt actccttcaa tttgtttcta taagctttca
    33121 tttgatacgc ccaaccttga tctgagtgaa acgtacgacg atagggacaa tcgttagtgg
    33181 tctggatagc ttcctccaaa ccttccatta ccgctaatgc attgggcttt tcagagatac
    33241 gataggataa aatctcacta ttgaacatat ccataaaagg atctagatac aatttctttt
    33301 gacggataat gcctttggca tccacttcat ggtatttaaa ttcagttgta tccgtcgtga
    33361 ttttctgatg gcagatactg gtgtagaaac gacgatggat ccgatttttg gctactgctc
    33421 caacttttcc tcgataagaa ttgtagcgac gtgatttacg cgtgtatgcc gttactttta
    33481 ttcctagctt cttgatcaag cgctgaactt tctttttatt gatagagaaa ccgcggtttc
    33541 ttagttcatt ggtcatccgt aaacagccat aatccttgtg cttctcccga attttaagca
    33601 tttccgcttc aatctcttga tctggatttt tacggtccaa tcgcctttgc catccaaata
    33661 atcatgaacg atctttaatt taagttcaaa agtatattta accataaaaa ataccgacct
    33721 ccaaaagtta gattttttgg tctaactttt gggggtcggt acacaaatcg tgtcacagtc
    33781 ccttttttga aaataaacgg tgttcaaaag cttgcatctg cggtaataag tccagccaag
    33841 ttaaaaacat aagaagctgt ttttacttgg ctgttcttat tacttgatgc aaggcagctt
    33901 tttcacaacc tcttttcaaa tatttcgttt tcttattcta caaatggttc ttctcctaac
    33961 gcttgttgag cggctagatt caacatgctc cattgtcggt caaagcctgg ctggaagaag
    34021 aagtcagctt ctgctagttc ttctaaagtc agtttgtttt ggatcgctag tgccaataca
    34081 tttccttgac ctgtaacatc ataggtagat aatactgctc ctcctagcaa ttgatgggtc
    34141 attggatccg agaataattg gatggacact tttggatttc cttgttcttc tggtacatat
    34201 tttggtcgta acgtatcttc ataataagac actcgtacat ctactcctgc ttttgctgct
    34261 gtaaagctat tcaatccgct tgctgcaaaa tgatagtcaa agacacttaa tgcagaggaa
    34321 cctacgactc cgccgaacgg tttgtttggt acttcttcaa aaagatgttt tactacataa
    34381 cgtgcttctc tacgtgcaac agtcgctaaa gcgatcggca tttttttgcg tgctgggata
    34441 gaataagcaa gtgtagcatc tcctactgca tacacatctg gaagattcgt ttgcaagtat
    34501 tcatttgttt ggatccagcc acgttcatct aagtcgacga tcccttttaa ccattctgta
    34561 tttgccttca caccggcagc ttgaatgact agatctgctg ggatttcttt ttcacttgtt
    34621 ttgattgcct caacttttcc gttaccagta aaagcttcga tttttgcatt tgtcaaaact
    34681 tcaataccgt tttcatttag gtgttgttct aaaatatctg tcatctcagc atctaaataa
    34741 gtgcctaaag gtctatcgat cacatcaagc aatacgactt ctttcccagc ttttcggctt
    34801 gcttctgctg cttcgatccc aatgtaaccc gcacctacga cagcgatttt tttaatagcc
    34861 ggatcattta atttttcttt gattttggtt gcccaattgt atccacgcat caagtagaca
    34921 ttttctagat ctgctcctgg tactggcaga ttgtttggtt tgacaccaga actcaaaatc
    34981 aatttgtcat aaggatattc ttttgtttcg ttatctgatg cgctagtaac cgttactgtt
    35041 tttttatcgg catcgatcgt ttttacttcg tgattattta aaatatgaac attggattgc
    35101 ggaaagtttt ctggtctgaa attacgtaca tcatttacat ctgttacctt gtcttctaaa
    35161 tacagctcca taccacatga catgaaggaa atatagtctc ctgcttcaaa tagcgtgata
    35221 tctacatttt caccgtatcg tgtcaatagt tccaagatcg attgatgccc tccatgagat
    35281 gcacctacaa tgacaacttt gattttttcc attgatgaaa cctccttgaa tattctttta
    35341 aaatcattct aaacaattta aacttaacat tacattagtt atgaatcaaa agaaacgcgt
    35401 tcatttgaac taaatttaaa aaacaatcgt ctccttgcag aatataccgc aaaattaacg
    35461 attgtttttt tgataaaatc tatgaatcac tgttctgtta aaaagtcttt gatccgtttg
    35521 caggcctcat gtaatttttc catgctgcta gcataagaaa tccggatata accttctcct
    35581 tctgggccaa atgcaattcc tgggatacac gcaacttttg cctgttccgc taattctaca
    35641 caaaactgcc aagagtcagt ttgaatggca gctgggagtt tgcaaaacaa gtaaaatgca
    35701 ccgtttggct gggtcacttc aaatcctaaa ggcgccaatt gctggaccag atagtctctt
    35761 cgtgtttgat attgctcttt catattctcg ctatctttca ccccatttat tagcgcttca
    35821 gccgcagctt tttgcgacat cgttgtagcg gcagtcacca gatattgatg gactttaatt
    35881 agttcgtcaa taagggcttt ttgagcaaaa ataaagccca ctcgccaacc agtcatcgca
    35941 tgtgacttgg ataacccgct tatcacgatt gtttgttctg gaagataagt agctatggac
    36001 atatgcgttc cactataagt caattcagca tatacttcat cacttataac aaataccgga
    36061 tattttttta aaacctcagc gattgctttc aattgttttg cagacaatgt cgtcccagta
    36121 ggattgttag gatagtttaa aatgactgct ttgacagctg atccatattg ttcaaatgct
    36181 cgttcaaatt gttccggctg acagacaaac cctgtgtcag aagtatctat cgggatcaat
    36241 tcagcaccag ctagttccac taatggctga tatcctgaat aagcaggcgc tggaataaga
    36301 accttgtctc cttcttccaa aacagataac aacgcagagg caatcgcttc cgttgcacca
    36361 actgtcgtca aaacttccgt ttgcggatca taagttaatc cataacgctg ttgctgaaat
    36421 atacaagccg cttcccgcag ttcctctaat cctctcattc cggtatagtg agaaaagtct
    36481 tcttcaatcg ctgctattcc tgcttgcttg acatgttcag gagttggaaa atccggttct
    36541 cccagggtga gtttgatcac atctggtatc gacgatattt gctgatcgaa ttgtcgtatt
    36601 tttgatactt ctattctaga aagcctagga ctaaatcgat tggataaatt catcattatt
    36661 tactcgctcc tcttttgaac tgctatcgat ttttacaaga agattttctg taaaaagaat
    36721 cgttttgtac cattctacac cattttctaa aacatccata tcaaaatcga acgtcggatc
    36781 atgtaaagca ggggtatcac cgacacctaa aaagaaaaat acacatggat attgttgcgt
    36841 atatatgcca aaatcttcgg cttgaagaac tggagcatct aattcatgta gtttgtttga
    36901 atctaacagt gctgcatata agcctctatg gttgattaca gctggatagc cgtcattata
    36961 gcgaaaagaa atagtagctg tagagtgaaa ctgttctgct aaatggtcta atcccctctt
    37021 caaataattt tgcatatctg aactgtaaga acggatactt ccggatacaa taacttctcc
    37081 agctaaaaca tttcggatcg ttccaccttg gatttggcca aatttcatta gatgattcca
    37141 ctctgccggt aattgccggt caaaatcata aacattcttc aaaaatcgta cagctgcctc
    37201 cagactatcg attccttttt cactagaagc aatatgtgca gactggcctt taatgataat
    37261 gtctgtttca ctgctttgtg ccatcaaagg tcctggtcga gagaaaactt ctcccttagc
    37321 tagtccaggc catagatgaa agccaaatat tgcttgtact tcatatttat ccaacaatcc
    37381 tgactgaata acgctttgtg cgccaccgga aatttcttct gatggctgat agatcagtac
    37441 tacattataa ataagatcct caatgtgttt agttataaag tcagtcaacc ctaaaagcat
    37501 cgccatatgt ccgtcatgac cacatgcatg catataacct tcatgcttag aagcaaaaga
    37561 gagattcgtt tcttctttga ctggcagtgc atcgatatct gttcgaaaag caatcgtttc
    37621 ttcttgctga ttatcaaaat aaaggagtag tcctgtttcg ccgatttcat ggataacggc
    37681 ctcgctgttt tttacttgtt catataaata tttttttgtc ttgaattcat gaaacccgat
    37741 ttcaggaatt tgatggagtg ccattcgata ttctttcagc atccgtattc accatccctt
    37801 catagatacc cttcactact gtttcatatt gattattcgg tacaccgatg atcagattca
    37861 actcctgtgc tccttgtgat aagatcgatg tgcgaatttc taatttgttc aatatcgata
    37921 acactttccc agataatcca atcaattctt tatgcggacc cccaacgaca gagatcaaag
    37981 ctaagtcttc gatcacgacg atttcttcca cgccaagtgt ttcttttaat tctttcgtga
    38041 tgagaaataa cttatcggca atcgcttctg ctgagacgat cactccgata ttgtcgatcc
    38101 ctgaaggaat atgttcgatt gatatctcat gtttagcaaa aatgctcatt gctttccaga
    38161 taaacccgat ttcatcggac atatgacgtt tgaataaagt gatggaaaga aaatccttgc
    38221 gtccagctat tcctgtcagt ccattttcct tttctatttc gtgattcgat atttttgtcc
    38281 cttgagcgaa aggatcattg gtatttttta tttggatggg gatatcagcc tcttgaactg
    38341 ggaaaacagc tgcttcatga agaacgttag cccccatata agccatctct ctcagttctc
    38401 taaaagagat ttcctcgatg attttaggat gatcgatgat tcgcggatca gccatcatga
    38461 ttcctgaaac atccgtccaa ttctcataac tttccgcttg caacatcttc gccagtatcg
    38521 cgccggtaat gtcgcttccc ccacggccca ataatttttc ttttcctgca gggttcgccc
    38581 cgtaaaaccc tggaacaacc attttcggat atcttttaaa tgcttttgtg atttcctgtg
    38641 ctgttttttc ctgatcgatt ttcccatcat agtcaaagaa aatcaggtct tttgcgtcaa
    38701 taaactggta accaagatac tcagccatca gttgagcagt cagatattca cctctactta
    38761 ctaaataatc ttcagttatc ttttcgtctt ccagttgttt ctgtatgcgt gctagttcat
    38821 cttcaatagg taactgcagg gcaagaacat ctcttacttg aatgaaacga tcacaaatcc
    38881 ttttccaaag gggtgtccaa tcaacatgat gctgaaggta agcataaatc aaataaagta
    38941 agtctgttac tttgtcatca tctgacgtac gtttgcctaa agcagaaaca acgatcactt
    39001 ggcgattggg atctgaaaga acaattgtac ggactttttt gaattgctct tcatgagaca
    39061 tcgatgttcc gccgaatttc gctactttca gcgtattact catcttgcca cctccgctat
    39121 tttctgcatt aaagctgcag caatctgtac ggcattcgca gcggctcctt tgcgtatgtt
    39181 atcggcagtc gtatagaaca acaatccgtt ctctaaagaa gtgtcttttc tgatcctccc
    39241 aacataaacc atatctgttc ctctagcaag aatgctcgtc ggatatttat gtgctgctag
    39301 atcatcttct aattgaatcc ctggaaactg gctgagacac tctctaattt cttccgtcgt
    39361 aaactctttt tgcagttgaa ctgccacaga gactccatgt ccattttcga ttggcacacg
    39421 tacgcaggtt gctgatactg gcaaagcagg ctgatgcaga atcttacggg tctcatttat
    39481 cattttctgt tcttcttttg tatacccatt ttccaaaggc tgatcgattt ccggaatcac
    39541 cgtttggcta atattataag gatacaaaac tggttcctcg tcattttgcg tacgatgaag
    39601 atcttcaatg cctttttgcc cggaaccaga aactgcttga taggtcgaat aattgactcg
    39661 ctggatacca aaggcttctt gtaaagcttt aagcggaagt accgcttgaa tggttgaaca
    39721 atttggattt gcaatcagcc gattcaatgt atagtcttcc agattgacct ctggaacgat
    39781 taatggaata tccgaatctt cccgccatgc tgaggaatta tctatgacaa atagtccctg
    39841 acttcgtgcg attggcgcaa actctttgga tacagaagca cctgcagaaa atagcgctaa
    39901 atcatatcct tcaaatgaag tttctgtcaa ttcctgtaca gtgtgtttct ttttcttgaa
    39961 tacacaaact ttaccggctg aacgttttga agctaataat ttcaatcgtc ctactggaaa
    40021 atcatattct tctaacactt tgagcatcgt ttggccgact aatccggttg cccccacaat
    40081 acaggtatct atttcgcgca tttttctcca tctcctctat aattcgcgta acgcagcaat
    40141 caatgctgta ttttcttttg tctgatcatc acttattttt aatacacgtg caggtattcc
    40201 accgacaaca gtttctgctg ccacatcttc taaaaccact gctcctgctg ccacgactgc
    40261 atcttttccg atatggacac cttcaacaat cactgcattc gcacctacca gtacgccgtc
    40321 ttctacgata accggtttgg ccgatgctgg ttcgatcaca cctgctaaga cagctcctgc
    40381 accaatatgg cagtttttgc ccactgtcgc tcgtccacct aagacagcac ccatatcaat
    40441 catcgtgttt tcaccgatta ctgcaccaat attgataatc gctcccatca tgatcacggc
    40501 attgttgccg attgacactt gatctctgat aatagcacct ggttcgatac gagcattaat
    40561 ttttttaata tctagcaaag gaactgcgct gtatcttgca gcagtttcga tttcgatttc
    40621 aatgattttt tctgattcag cttctaaaac cggagcaatc gtctcatagt caccaaaaac
    40681 aacgaagctg cttccttcac caaaaacttt actttcttta aattcgattg gctcggttac
    40741 attcagatag actttcacag gcgtcttttt agatgccgtt tgaatgtagc ggatgatttc
    40801 ttgagcttcc acgtttttta cacccctttg tccattaata aatcttctaa tttgtaataa
    40861 cctggtgact gatctttcaa ccagtccgct gcttctactg cgcctgcagc aaagattcga
    40921 ttagaaaaag attcatgttt gatcgtaaat atttcatcag tagcagcaaa caatacatca
    40981 tgttcaccag gtaaagaacc tgcacgaata ctgtgtacac caatttggtt ttcttctctt
    41041 tttttccctt gccagttgta tacgggctgc agcttttgca cttcttggat tgtttgaagc
    41101 agcatatttg cagtaccaga tggtgcatct tttttacgac tatgatgttt ttcaatcagt
    41161 tcgatctgcc agccttgcaa cattgcagct gcttgcttga ttagttgatt catcaccatg
    41221 atgccgaacg aaaaattagc actatacatc acaggtacat gtttggcatg ttcttttatt
    41281 tcttggaact gtgattgtgt ataacctgtc gtgccaatga ctaacggaag ttgatatgat
    41341 aagctatacg aaaggatttt ctctaaatta tctggatgag aaaaatcaat aagcagttct
    41401 ggcagttccg taaaagcaag cgtagttgct tctttaggtg ccgtccgtaa aagaaggacc
    41461 gtatctcctc tttcttgtgc aacttcttcg actctatttc ccatctgtcc actgccaatc
    41521 agtccgattt tcatttttca accgtccttt cttttaacaa aagctgagct aattgtttct
    41581 ttttctcttt tgaaagagaa actaaaggca ggcgtagagg tccggaaggt aagtctaata
    41641 atgacatggc tgctttgaca ggaataggat tggtctcact gaacaaggca tggatcagtt
    41701 caagtgcatt taattgcttt tcttttgctt gctgccatct tccgtcctgc gtatctttta
    41761 ctaattcatg gactatttta ggttggatat tcgcccatac acttattaca ccgcttcctc
    41821 ctacactcat tactggtagg atcaaatcat catttccact gtaaaggaag aattcttctc
    41881 caatcaaccg agcggcatcc atcacataag ccatatctcc tgaggcttct ttcaaaccaa
    41941 tgatattagg atgttctgct aaatttacta atacatggat tggaatcgac atgcctgttc
    42001 tagaaggaac attatacaaa ataagcggaa tcggtgaggc ttctgcaatt gctgtaaaat
    42061 gagcagctag tcctgcatca cttgttttgt tgtagtaagg ggtgatgacc aaaagtgcgt
    42121 ctgcccccaa agaagcaaaa tgcttcgctt tttcaatcgt ttctttcgta ttattcgttc
    42181 cagctcctgc aatcaccggc acacggccag ccactttctt tactgtcagt tgaaggatct
    42241 gctcctcctc agattgtgtg agcgtagaag attctcctgt tgtacctaaa actaataatc
    42301 catctgtttg ttcatctaaa tggaattgga tcaatttttc caaaccagca taatctactg
    42361 atccctcttc attcatcggc gtgatcagcg ccacgatcga accttttatc atcttcattc
    42421 ctccaatatt cttgtccatt catgaactgc tgggccagcc atttgtatcg catcctcacc
    42481 agagatcatc aagtctcctt gttccaagtg aacaactacc tgatctgctg aaattttccc
    42541 agtttcctta gcaaccacat aagaggcaca gcaacctgta ccgcaagcaa gtgtccaacc
    42601 tactcctctt tcataggtac ggacgatcaa ttcttgttca ttgactactt ctacaaagtt
    42661 gacattggtt ttttctttga acaaaggatg atgacagatc agttcacctc tttttctcca
    42721 gacttcctca cgcgcatttt caacaaaaac aacggtatga atcgttccta aaaataaact
    42781 agtgatcgtt actttttcac cattgatctc tatttcctgg ttttttattg gataagtttg
    42841 attagctttg attttttccg gagaatcatc tggcactccc atatctacgc tgcaataaaa
    42901 aggtgaggga tccaacaccg taatttttct tgtgcctgct aatgtctcta cgttgaattc
    42961 ctgttcattc atcatgttct gatcatttac gtatcgagca aaacagcgaa tgccatttcc
    43021 gcacatcggc gcgcggctgc catctttgtt gtaatagatc atttccaacg gatcgatttt
    43081 tacggcgatc aatccgtcta tatcatattt ttcttttgtg cataaagaag cggctaattg
    43141 actataatct gtgtcttctg cgtaatctaa taagataaaa tcatttccgc agccattata
    43201 tttatgaagg atcataggaa acttcccccc ttagtagatc agaaaatgct tgtctgcgaa
    43261 caatcagtct tgattggcca ttattgacaa aaacaactgc tggtcgtgtc gctcgattgt
    43321 agttgctgct catcgagtat ccataagctc ccgtggaata aacagctaaa agatcacccg
    43381 attctgcttt cggcaaataa gcttctttaa ttaccacatc gcctgattca cacatttttc
    43441 ctgcaatcgt cactttctct gttttttctt ccgacagttt tgctgctaaa tcacaatcgt
    43501 attctgcctg atacagagct ggacggatat tatctgtcat cccgccatct acaaagtaat
    43561 attttttatg tggtgtcttt ttgatgaaac caatcgtgta tagtgttgta ccagcttctc
    43621 caacaatact tctacccggt tcgatcagta attgacgaat ggtcagtttt cgtttttcca
    43681 aagcttcttc cgtatattca atcagttttt ttagtgcctc ttcgactggg atcggctgat
    43741 cattttgtgt ataacgaatc ccaaaccctc cgccaagatt caaggaaaga ggttggtcaa
    43801 aatcggttaa gtaattcgtc aatttgtcga tttcagctaa ccaagcagta acatcaaaaa
    43861 tttgtgaccc gatatgagca tgaaatcctt ctaactctag atagctgctt tcttttatca
    43921 actgaagggc ttgttggcac tctttacttt catagctcat gccgaatttt gaatcaatat
    43981 gcgcagtgac gatatattca tgagtatgtg cttctactcc gacattcaac cgaagcatga
    44041 tacagatttt ttttaaatag cgttggctta attctgctaa taattcaact tccatcaaat
    44101 tatcggcaac aatatgcaac aaatcatttt caagtgcata gatcagttcc tctggcgtct
    44161 tgttgttacc atggaagtag atagtatctc taggaaaatc agcttgcaaa gcggtataga
    44221 tttccccacc actgacaaca tctagcccga atccatattc acgaactaaa tgcagcatct
    44281 caatcgtttg gaatgcttta gaggcgtaaa gcacttttgt atcaaaacgt ttcgatacaa
    44341 agcctcgctt gaatgacagc atcgtttgtc tcatcttttc ttcatcatac acatacagag
    44401 gtgtcttata cttttctgcc aatgtgcttg ctgtgactcc gccaattatc aattctgtca
    44461 ttttttcatt cctcttttca ctttttttcc gtttttattg gaatttcatt tgataaagat
    44521 ttgaatttta ttggaataat attaaacaaa
//
LOCUS       DACCVZ010000017        43760 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.017, whole genome shotgun sequence.
ACCESSION   DACCVZ010000017 DACCVZ010000000
VERSION     DACCVZ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.017"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            174..518
                     /locus_tag="IVW63_000884"
     CDS             174..518
                     /locus_tag="IVW63_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAP7859178.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            519..938
                     /locus_tag="IVW63_000885"
     CDS             519..938
                     /locus_tag="IVW63_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAP7859179.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1030..1380)
                     /locus_tag="IVW63_000886"
     CDS             complement(1030..1380)
                     /locus_tag="IVW63_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859180.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1346..2667)
                     /locus_tag="IVW63_000887"
                     /pseudo
     CDS             complement(1346..2667)
                     /locus_tag="IVW63_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
     gene            2923..3489
                     /locus_tag="IVW63_000888"
     CDS             2923..3489
                     /locus_tag="IVW63_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7859181.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3634..3721
                     /locus_tag="IVW63_000889"
     tRNA            3634..3721
                     /locus_tag="IVW63_000889"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3666..3668,aa:Ser,seq:cga)
     gene            complement(3773..4978)
                     /locus_tag="IVW63_000890"
     CDS             complement(3773..4978)
                     /locus_tag="IVW63_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7859182.1"
                     /translation="MAKKEIDKRIKKHLTKKGEEKYQFSLYLGVDPLTGKKRKTTRRG
                     FSTPLAAERALKRLEADIQEKGLQASTAQKSKKFEYVYGLWFENYKKTVKESTWSSTK
                     QIFDTHILKVFGDKFIDKIDVFFCQEAVNTWSDSHPKIFKKIKNYTSNVFDYAASLQI
                     ITSNPMKLVSIPRGEALDIEDKNIEFYTKEELIKFLEAIRNDDDERYLFFSLLAFTGI
                     RKGEAFALTWSDIDFKSKTLNINKTVTRGYQGRLIVNTPKSKSGKRKIYLDNDLISLL
                     RKYYTKNKTIVTIQRENLIFHHDGLLYNPTVSRSWLNVIYKHHPELTKRITTHGFRHT
                     HASLLFESGASLKDVQERLGHADIQTTSNIYTHVTETQNKKVINNFVAFMKNSTQGES
                     KGESKNILG"
     gene            complement(5116..6004)
                     /locus_tag="IVW63_000891"
                     /pseudo
     CDS             complement(5116..6004)
                     /locus_tag="IVW63_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317363.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
     gene            complement(6091..6291)
                     /locus_tag="IVW63_000892"
     CDS             complement(6091..6291)
                     /locus_tag="IVW63_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859183.1"
                     /translation="MKIGMRKPSIKKSISARTTGKAKRKVKKAVIPGYGKKGSGWIKD
                     PKKAAYNKVYKKTTFSFWDLFK"
     gene            complement(6320..6742)
                     /locus_tag="IVW63_000893"
     CDS             complement(6320..6742)
                     /locus_tag="IVW63_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP7859184.1"
                     /translation="MYLPQIDNKINKLVKLYQTRNPFRIARELKILVLEEDLGEIYGY
                     YSKFKQIKMIHINSSLDEMGKWITCSHELGHCVLHPNENTPMLSKKTLVSELKIEKEA
                     NYFATHLTIDPTLDGFDHMTKYEKLVCFGLPDEFDRFL"
     gene            complement(6759..7181)
                     /locus_tag="IVW63_000894"
     CDS             complement(6759..7181)
                     /locus_tag="IVW63_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7859185.1"
                     /translation="MTTFERIKELAKNKNKNLQQVAKDLKYGENYFYSLNAGKQPTAE
                     KLQEIADYFDVSVDYLLGRTEKKRYYDLTEKDERDIQKELQSLIDDLSNADGMAFSKK
                     DNEMSEATREALIISLENALRIAKIEAKKKYTPKKYRD"
     gene            7472..7663
                     /locus_tag="IVW63_000895"
     CDS             7472..7663
                     /locus_tag="IVW63_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859186.1"
                     /translation="MSNLDNGRAAIKEFMKENGITMDDLATAYGHTRVRMQQILDGHW
                     SGPKANRTILEIIRDYRIR"
     gene            7674..7940
                     /locus_tag="IVW63_000896"
     CDS             7674..7940
                     /locus_tag="IVW63_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859187.1"
                     /translation="MNILSEEFLTRLRIAIVEVVKDALSQLSKKNLSETRYLKKIEAR
                     KYVGGVNDQGFEKLIAHGLKEIRIDGFLRYDKKDIDELMAKYKI"
     gene            complement(8181..8660)
                     /locus_tag="IVW63_000897"
     CDS             complement(8181..8660)
                     /locus_tag="IVW63_000897"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859188.1"
                     /translation="MSRKIDNIILLTTIFYLVIGATLSLLSFLSNSSLIVLNQKSILT
                     EFAHIDYFSFFKTGLICLFLSSFILYIGTTFCLMVLNLKMFIIEKWIVIIAKIFSSIS
                     IIIPMTLTFSKEQFNVATTFVSFIALFSFAVPKTFQSKSSNAKVNVENTDRKNDESY"
     gene            8705..9412
                     /locus_tag="IVW63_000898"
     CDS             8705..9412
                     /locus_tag="IVW63_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAP7859189.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFDKKHRHVLTAIDELKEGVAEN
                     WADLFWEDTYVHPQNKQSYRIIYMNRDGFSLLAMGFTGKKALSFKLQYIEAFNKMEKE
                     LKDQLPSIPATKREMALLALAANEETNERVDAIESDLNDLKNNQLLAEPDYRTISNMV
                     RNKIRVICNQQHLNSKAKAELFKDLNGGIKRITGAVARNRIKAKQFDDVIDFINNWMP
                     STATMTIIKQMELLEDE"
     gene            9591..9932
                     /locus_tag="IVW63_000899"
     CDS             9591..9932
                     /locus_tag="IVW63_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859190.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKTEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            9925..10671
                     /locus_tag="IVW63_000900"
     CDS             9925..10671
                     /locus_tag="IVW63_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAP7859191.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFDKKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWIEDQYREETKEK"
     gene            10677..11363
                     /locus_tag="IVW63_000901"
     CDS             10677..11363
                     /locus_tag="IVW63_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859192.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHNIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            11370..12203
                     /locus_tag="IVW63_000902"
     CDS             11370..12203
                     /locus_tag="IVW63_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer"
                     /protein_id="HAP7859193.1"
                     /translation="MSDNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIDVLDNGAIYMSDI
                     QSFIGKSSTEADRKREYRKKIEEAKRNLITGGQVSDKCPDKTTPELEIEIEKDIDIDK
                     EEKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEY
                     VINWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLP
                     I"
     gene            12220..13071
                     /locus_tag="IVW63_000903"
     CDS             12220..13071
                     /locus_tag="IVW63_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP7859194.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            13068..13427
                     /locus_tag="IVW63_000904"
     CDS             13068..13427
                     /locus_tag="IVW63_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HAP7859195.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            13442..13603
                     /locus_tag="IVW63_000905"
     CDS             13442..13603
                     /locus_tag="IVW63_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAP7859196.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERIKAVMVNETARKAINLHIVNL
                     RREIRRLEE"
     gene            13600..13905
                     /locus_tag="IVW63_000906"
     CDS             13600..13905
                     /locus_tag="IVW63_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859197.1"
                     /translation="MSVGKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPK
                     RKTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            13905..14219
                     /locus_tag="IVW63_000907"
     CDS             13905..14219
                     /locus_tag="IVW63_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAP7859198.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKAKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYREILNEYFE
                     ED"
     gene            14396..14707
                     /locus_tag="IVW63_000908"
     CDS             14396..14707
                     /locus_tag="IVW63_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859199.1"
                     /translation="MDELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            14704..14922
                     /locus_tag="IVW63_000909"
     CDS             14704..14922
                     /locus_tag="IVW63_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HAP7859200.1"
                     /translation="MISLTIFWCVIGGLLAMLGAYLIYESAKGKKYTAVGIILFVVGI
                     LVAIGAEINLYLNGTTEELMWFLLWTRR"
     gene            14935..15216
                     /locus_tag="IVW63_000910"
     CDS             14935..15216
                     /locus_tag="IVW63_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859201.1"
                     /translation="MGDMGEYWKDIKPHLKERRKQHVRKMGNSATKNIETLGFEFTHY
                     PNNHQFAINTHNGIIDYWGTTGTWIERKTKKRGKGIRSLRKYINQEDSK"
     gene            15213..15539
                     /locus_tag="IVW63_000911"
     CDS             15213..15539
                     /locus_tag="IVW63_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859202.1"
                     /translation="MNYTQQELTDLCPKHVAEFINNEVLPKYADGLNTAENVTDFMIN
                     DAIDRLIFLEIDCIAYYRLHAEVALIDPYIALSQNRKILVAYIDTKQILEGRDVEIEI
                     DEEEVG"
     gene            15536..15733
                     /locus_tag="IVW63_000912"
     CDS             15536..15733
                     /locus_tag="IVW63_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859203.1"
                     /translation="MKAYTIKFYGNKTYVYILSGLRLDFRGYSKEDLLESLYGYGYLN
                     EDELISLEKFTNAWTIEEEAE"
     gene            15730..15939
                     /locus_tag="IVW63_000913"
     CDS             15730..15939
                     /locus_tag="IVW63_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859204.1"
                     /translation="MKIYVVKFGNKFYRSDERSIGANTLFIVDILQSARWFDSLEEAN
                     QVSRRLGGLTQVYELVTVDHEEVER"
     gene            15936..16223
                     /locus_tag="IVW63_000914"
     CDS             15936..16223
                     /locus_tag="IVW63_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859205.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKKRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMKAI"
     gene            16816..17283
                     /locus_tag="IVW63_000915"
     CDS             16816..17283
                     /locus_tag="IVW63_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HAP7859206.1"
                     /translation="MVLFDVKKYETPEAKDVDMDRTKHNVGVFLSAYLSARCRIGQPR
                     EPKVTASYSLVPPSTANNTFEAERMMIEREEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            17582..17923
                     /locus_tag="IVW63_000916"
     CDS             17582..17923
                     /locus_tag="IVW63_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859207.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDPRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(17916..18095)
                     /locus_tag="IVW63_000917"
     CDS             complement(17916..18095)
                     /locus_tag="IVW63_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HAP7859208.1"
                     /translation="MYFVIREATNGQYYFVIKSDNNEVVATSETYLTKYSAEQTINSI
                     KNGITKDSQVIDVTK"
     gene            18457..18669
                     /locus_tag="IVW63_000918"
     CDS             18457..18669
                     /locus_tag="IVW63_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859209.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQAKYFYDQL
                     ILQGFNDAQAMEFMMRTFSASNQQKE"
     gene            18676..18900
                     /locus_tag="IVW63_000919"
     CDS             18676..18900
                     /locus_tag="IVW63_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859210.1"
                     /translation="MRNYWYVSLSNKYPQPNADDPIRVVQSVQIKKKYSIIEMTREAT
                     PKEIDKYNLRYCGHGYFSEQNIQTNIERYC"
     gene            18927..19460
                     /locus_tag="IVW63_000920"
     CDS             18927..19460
                     /locus_tag="IVW63_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HAP7859211.1"
                     /translation="MVNLTPKQKAFADEYIKNGGNATQAAIKAGYSKRSARVIGKENL
                     TKPNIIQYINERLNPIEKKRKLSAEDALNELIDIWQGEVQISVSKQIDRLEKNKVIKH
                     MQYEYTPDLESKLKALDLYLKYKSLLSQTQLEKAQTEIKLMQAKLEQLQINSERSTEE
                     KLDELLEKISGELDGTS"
     gene            19447..20691
                     /locus_tag="IVW63_000921"
     CDS             19447..20691
                     /locus_tag="IVW63_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HAP7859212.1"
                     /translation="MALVDIYNPKQIDVLNKTIKNDWFITLLHGAKRSGKTKINNDLF
                     LFELRRVRKIADEEDIKEPMYILAGVSSATIQKNILQELYNMYSIEPKFDKHGNFKLF
                     GVKVVQAYTGNIGGVGAIRGMTAYGAYINEASLARQEVFAEIVSRCSGTGARILADTN
                     PDNPEHWLKKEYIDNSSKNIQSFHFELDDNTFLSERYRNNIKESTPSGMFYDRDIKGL
                     WVSAEGVVYRDFDASKHYIQSKDLPPLSNFYCGVDWGYEHWGSIVVIGETDDGTAYLI
                     EEHATQFEEIDYWVDVAKGIQERYGLRVPFYCDSARPEHVARFVREKINAKNAHKARL
                     SGVEEVAKRFKQDKLFICQDRVMKFRDEIYQYIWDKKKGEPIKEYDDVLDSVRYAIYT
                     HELLKKPKVNVNEKIKRIKRMF"
     gene            20704..22203
                     /locus_tag="IVW63_000922"
     CDS             20704..22203
                     /locus_tag="IVW63_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP7859213.1"
                     /translation="MDKVNEFEYGADIHYSNDVNTNYVKFSVDSNLHYRFSSAEDLLN
                     DLDTLAAMIKHHHEYQVKRLSVLDDYYKARNTNIMDNRRRREKEKADHRSAHNFGKVL
                     CTFDVGYNTGNPIKVQIEDTNQQKEIEEFNTNNDIDGLNDELWLDMDKYGRAYEIIYR
                     DSDDTDYVDLANVFETFVVYDTTVKREPILAVRYPKTRFNKDADKQYIQPIVYTKEKS
                     ITYDETTLTAIELKNPQDEPHEYKEVPITEYSPNRFRMGLYEDVLSLIDLYDAGQSDT
                     ANYMTDLNDALLVISGDIEAAGLSTEDAIKQKEANMLLLESGTDVNGNKTSVTAGYIY
                     KQYDVNGVEAYKYRVRKDIHEISMVPDLTDDNFSGVQSGEAMKYKLFGFEQMTATKQR
                     LFKKGLMRRYRLLFSLKSSISEMDNSDLKGLRVIFTPNLPKAILEELKSLVDAGAELS
                     QETILGLASFVPDVQAELKRVNKETQKQIGIFDSDGEEVINNKKDETGG"
     gene            22208..23134
                     /locus_tag="IVW63_000923"
     CDS             22208..23134
                     /locus_tag="IVW63_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAP7859214.1"
                     /translation="MNSQEYWIKREKEWQKQQIKDDKKRMAEIKSRMQYAQDAIQKEI
                     DAQWDSFSNGQKITRSEAMKRASEMDVKAFARKAKKYVKEKDFSPTANQELKLYNLTM
                     RVNRLELLKANIGLELISLFNELDKYFSNELTKAGLAELKRQAGILEMTIASSGYAKL
                     IELVINSSFLSDDVSFSDRLWMYQSELKSELDRLLVRSITMGKNPKQLASKLAEYLTA
                     EGRENTKFNTQRLMVTETTRVQVGIQERSYRDAGITQYIYIAEPTACKLCIPLNNQVF
                     DVADMQPGSNAPNMHPFCRCSTAPYIERISSR"
     gene            23261..23863
                     /locus_tag="IVW63_000924"
     CDS             23261..23863
                     /locus_tag="IVW63_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HAP7859215.1"
                     /translation="MKKRLFMPMNLQFFSEPGDGGSGDEGQQGNLPAGSQETPPEAKE
                     ENNTGKTFSRDEVAKMIAAETNKAKAAWEKELAAKKEEAKKLAKMNAEEKLQHELEQK
                     EAEIAELKRGQALSEMTKEASKMLTDANLPHDDDLLGLIVSDDADATKQAVAVITNFA
                     SLIKRENARQTPPNEGGQFTASKNTKETVAKLAAKNRIIK"
     gene            23876..24799
                     /locus_tag="IVW63_000925"
     CDS             23876..24799
                     /locus_tag="IVW63_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAP7859216.1"
                     /translation="MKKKQLLPMNLQMFAQTWDPDNVLVYETKEGKIPDKYNTLILSE
                     VMENSKIMQLAKYEEMTDKEKKFEYFAEGPGAYWVGEGEKIKTSKPKWMQATMTAKKL
                     GVILPVSREYLNYKLSDFFEEMQPKIAEAFYKKFDAAALLNKENPFPQSLDGSVISAG
                     NVVEGGLTYDNILALEDKLAENEFEPNAFISNRKNRTELRSAAQTVGSNVEFIYDRST
                     NTIDGLPVVDLKSLDKGTLYAGDFNYMFYGIPYNISFKISEEAQLSTLTNEDGTPVNL
                     FEQELIALRATMDVGFMIVKDEAFGKISPKA"
     gene            24817..25080
                     /locus_tag="IVW63_000926"
     CDS             24817..25080
                     /locus_tag="IVW63_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859217.1"
                     /translation="MPNQKTWTGKVGDTKTFTISAVPADASDAAAVVAATTATSSDGA
                     IATVTKNENGGFDGTIAAEGSATFTFTSGEFTTSINVTGQPAS"
     gene            25092..25421
                     /locus_tag="IVW63_000927"
     CDS             25092..25421
                     /locus_tag="IVW63_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HAP7859218.1"
                     /translation="MMIADDIKKLLKGTIDEKLEVIERRTNERMKTLLNTQEVPKEFE
                     TVVYEVSLKRFNRIGQEGMQSYSQEGLSMAFPDSDFSEYQNEIDEFKRKDQEELYKPK
                     RGRFKFV"
     gene            25418..25744
                     /locus_tag="IVW63_000928"
     CDS             25418..25744
                     /locus_tag="IVW63_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859219.1"
                     /translation="MRFTDEIIFVKRSSDSKYDPDLGEWVEGKPERTRTEANVTDIGT
                     DRSVTIFGSVEEGAKVIRTQPLFSIPTFDYIEIEGKTWQQKTARNPAYRNSLIVQEVV
                     LDEGTT"
     gene            25728..26066
                     /locus_tag="IVW63_000929"
     CDS             25728..26066
                     /locus_tag="IVW63_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAP7859220.1"
                     /translation="MKAQLEYKGIDQLMRHLKKAATLNDVQKVVKSNTAEMTERMQKG
                     APVDTGYLRRSINMNLLEAGLTGIVGPTADYAPYVEYGTRFMSAQPYVRPAFNYQKVK
                     FMAEMKALVK"
     gene            26066..26458
                     /locus_tag="IVW63_000930"
     CDS             26066..26458
                     /locus_tag="IVW63_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HAP7859221.1"
                     /translation="MIKTRDQSIFDELFKISQNKLGYKTYDYKTLEDVGYPFVEFENT
                     QTIHEVNKTDIKGSVIVVLSVWGLQKKRKQLSDMASALFNEARLIEATEGYYWALNYQ
                     ASGIQVMDDTTTNTPLKRAVVTLEFRIR"
     gene            26469..26981
                     /locus_tag="IVW63_000931"
     CDS             26469..26981
                     /locus_tag="IVW63_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HAP7859222.1"
                     /translation="MEALKGIDVILLYRLLKKETQEAAWKMAFQTEHENGLSRDSDST
                     VTKDGNVQSLSPVEYDFSATSIVAKGDSHVDEMKQALLNGDIIEIWEINKAEQGTDDN
                     ANKYKATYYQAYVSEFTPSAAAEDNVELSLSFAVNGVGQDGYATLTEDQADVVQYAFK
                     DTVKATSTGA"
     gene            27027..27395
                     /locus_tag="IVW63_000932"
     CDS             27027..27395
                     /locus_tag="IVW63_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859223.1"
                     /translation="MKLKIKGKEYSFKFGTKFVRELDKVMPFVDGNMEFGMGLSAKVL
                     PELRSYNVNTLSRVLEIANRTEDESITLDELDDYIDEVKDIEKLFDEVLKELAESNAG
                     KLAVRNLNQKLKEAEKQQVE"
     gene            27449..27736
                     /locus_tag="IVW63_000933"
     CDS             27449..27736
                     /locus_tag="IVW63_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859224.1"
                     /translation="MTNISDIERMTLYEYNIRMTAAQLSWLDKEKLIHELAWANQQVQ
                     AEKKVGKKTVPVYRSFEEFFNYQKIEDSIMGVSELSKQDKKFQSLLTKANS"
     gene            27753..30872
                     /locus_tag="IVW63_000934"
     CDS             27753..30872
                     /locus_tag="IVW63_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAP7859225.1"
                     /translation="MEQFSVEALLKATDSGFVKTFKDAQDAVKTFEKNSNSMTTAVGK
                     VMQGTGAAMTKYITTPLIGVGVAAAKVGGDFEAQMSRVKAISGATGDTFEQMKQQAID
                     LGAKTAFSAKESAAGMENLASAGFSAQEIMKAMPGLLDLAAVSGGDVALASENTATAL
                     RGFGLEASEAGHVADVFARAAADTNAEVGDMGEALKYVAPVANSMGISLEETAAAIGI
                     MSDAGIKGSQAGTTLRGALSRLARPTKAMQDTMDNLGVSFYDADGKMKPLKTQVELLK
                     KAFEGLTPEQQQNALVTLYGQESLSGMMALIDKGPDSLGKLTKSLKDSDGAADDMART
                     MQDNMNSSIEQMFGAFESAAIVIQKILAPSIKKVADAISGLVEKFVSAPESTQKLVVA
                     IGAIVAAIGPLIFMIGSVIIWINRVKVAFKALSESSKLFSGLSKAMGLLTNPVFLVIA
                     AVALLVVGFIYLWNTSEDFRNFWIGLWEGIKSAVSSAVEWIQNAWKSTGEWFNNLWKS
                     IKEGADNVWTTVQEAPGKAADWIKNKWTGTKEFFSNLWSSIANSASEIWNSLKEGVIS
                     VIDDLVSSAGEKWEGFKNTISTAWKTITSKIKSGFDFILKYIGPFVSSFSDVFSNIVK
                     AITSIFAEVKNIIVNAWEIIKSLIAAPLLFIIDLITGDFEQMKEDLDLIWNTLVQSVV
                     NIWTSVKNIFTEYIGAIVNSAVSLWTGFIQSISNIWNEVVYQATMIWIDLKLFFTNLW
                     IDIKYSAIQMWINLKFSIIQTWIDTKYGAIELWNNLKQWFFQTVNNIVQTLIKSWNSL
                     KQGTIDLFNNTVQGAKDIWTSFKSWIGDLITGTKDNIIQGWENLKQGTIDTFNNLVNG
                     AQEAWDNLVNAVSDTVDRVTGWFDNLKNIDLLAAGKAIMDSFLEGLQNAWKSVQDFVG
                     GIGDWIREHKGPIQYDRKLLIPAGQAIMNGLNKGLTGGFNDVQNTVGSMADFIAELFN
                     ANSDVDIAANLKNANKNIGAQVEHKINMGGSTKPAVFKINLGRQSFRLFMDDISQAMG
                     EGADINLEF"
     gene            30905..31672
                     /locus_tag="IVW63_000935"
     CDS             30905..31672
                     /locus_tag="IVW63_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP7859226.1"
                     /translation="MYSFKDTTINLTSSKRFLPTSAMMYDGMYLEDLIDGYQTLTVEG
                     REMLSVEVEQQEIQIGSIITNQKIPSRTLKITYKLEDRDPEKLQFKFKELLNYLYRNE
                     DVEIRFHDELDYYYYGRYTSTDTVPGDSNSIISSFNVFCADPLKYTKECVSDGYIGNP
                     IQFPITPRKIEVTLSMNNSIKITNGEQNITITDAAIKTGDVLVFDFSDEQVTVNGEDC
                     TSMIDLESDFENFYLKQGQKITSNNGKLKIFYRGATI"
     gene            31669..34500
                     /locus_tag="IVW63_000936"
     CDS             31669..34500
                     /locus_tag="IVW63_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAP7859227.1"
                     /translation="MSETVYFFDHLQKLIKRKNTRSLIEVSQEKEISSDKSDLMKDTL
                     YVTTKYDKEIEDARYMAIRENESSFSLYRITKVSDPFETLEFTGLGFATNELDAYIIK
                     DIRPSGQPLKNVLDRLIEFTEGNWRVGHVEAMLPTVTATFYYVSVKEALKELQTLGME
                     FVFRCSLNSDGIKDKWIEVYEQIGEESNTRFVYGSKALTVVREIDRSSISTSMIGRGR
                     GEEVGDGYGRRIEFTDVEWKKSNGDPLDKPKGQNRLEDPESTQKYGIPQKDGSMRKRE
                     TVVVFDDIDDPTDLLKNTYSTLIDSARPLVQFKAEVTGGDVIGNTVTIHRYDKGYHYK
                     TRIYKTTFNRLTGQTNIELGDNLTQDVRKQTASIVNNINSLESSKMTFYESTEIGKYQ
                     DDIMRGAGDNGGSIYWVNGIEAGVSDSREIYETVYMDGPNIPRSRFFMVQNNSGISFK
                     QCKKGEWQTIQDVHNGDSTTAWTLDGTFNANFIRAGILSGILVQGVALKTFDDKDFQL
                     VAEGGELSFEKQVKSTGLDDVHGERLGSIVSTYGSKGINGFAVWKEPNYIFSINAGDG
                     GDRGNPIFQIPADVTADKRKYNLYGDGNFSEGNITIDGRLDVKELYVNGTKIDTNGGG
                     NSGGNDNGWNGQYPPEVTTDRDKRYWQIWATAIGAGFTQQAAAALLGNAQGESDANPT
                     ADEGNGAPGFGYGVWQWTDSSGATSGRVYMINLMTKAGISDDPDTITAQFKLLMWHAP
                     NGQWIATSAYPYTWTQFMNLTDINTAAQAFVANFERPRDPHPERTAWSQEWYDKFKDL
                     EIPVSKGYMKPIADPITVTSEFGWRTSPITGAQEFHNGIDLVNGNPNTPIFASADGEV
                     IVAGDANYFDWYGNWTVIKHADGMYTGYAHQSRVDVSKGQKVTAGQQIGLMGTTGPST
                     GEHLHFQFMDEFYPSSSGHFHNARDYIDF"
     gene            34475..36232
                     /locus_tag="IVW63_000937"
     CDS             34475..36232
                     /locus_tag="IVW63_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HAP7859228.1"
                     /translation="MQETTSISKGGIVMAETQHKMVLSTTEPNNGINLVRIRQGDVLT
                     QKFVVEVVEHGKLKTFEGLVPFFINTTKFGENQPVEQKVQEYSPAQARLVYTLSEPDW
                     QWGGENTAHFSFRSLNGDGTWSEQFSTQDFTYRVISGISRSQLRDSGYVWTFEDLLRK
                     FKDYMDQGKNDWEQWLEDNREILENIDPGGMIINILNEAKGDYESLADRLNQKYQVPV
                     GSSQIRETTRFFDYDTMKYVDLVPRNLNTVVNSVNNSKFNFSFITDIHADNHNLRIDG
                     VGYKDASYLRHWRAIPQFQKLGNKTDVMIYGGDNIDGGLGSLGSDIGIIDEWSARHSM
                     LGTLKRFTNAAVAGQEKPVIICKGNHDACFDPAWRKRKGMLCNADFEEYWNGLYGGVL
                     FPDKNAAIYRFDTCDFYEGGTGDKYVDGYSDTAPGAFSAKQINAFGEWLVNVPRNYHV
                     ALVGHTPLGLSKFPVRNENMISTLIEGFKSGSPVTIDWSKLGQPNDGSFGGLKTFAMN
                     TKGAGVVVGYFCGHWHEQVEGAFGTVKMILCDVGFSHTASQVDTPDELAFYKIEVDTA
                     TRKVTSKGVGRARDFTYNY"
     gene            36249..37031
                     /locus_tag="IVW63_000938"
     CDS             36249..37031
                     /locus_tag="IVW63_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859229.1"
                     /translation="MLDFQSKPNIFEEMSYEEAVKWLLRQAAIHYDGSDHDAHVLATE
                     SNAGFATPETVMQARGRWLRDYKLPQKYPNILDIPPGKYATKAGWGADNPDGIEDDSF
                     VEMMVFADHDSRKLIVAFARYSGEIYIKMTHNSEPVEGYNSLGWRRVYTTSVLFEGEL
                     RKGQSVNLPDDTFRYQTLRIHYTDGDGDFVEEVKRQRYARITKANLWNGDAGVTFIEF
                     ELTIEARKITMSNGRALDISSGNVSNPAMSNNVKITKIEGVK"
     gene            37031..39217
                     /locus_tag="IVW63_000939"
     CDS             37031..39217
                     /locus_tag="IVW63_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HAP7859230.1"
                     /translation="MAHVIKKGSIKVPTQPKDYDLQATGLVFKSYDNQIALEFNVEQQ
                     NGTPADLLGANLRLLMFIYDEVDGMITKEPIPFITKNLITESFLNGQVVYILPEAMKA
                     YNGMVEAYVYIEYPDGSTSDNLGFTFRMKRSAIDGLAQDKADYFIADFQQLLDGVKQE
                     ATDAVNAALTNVDSTIEKANQQINEFVEGATQAIDQTVDEVTEQLQATQTKIDTVSQN
                     VTSAQNNLKAVEDKMNQTNQQIGDLGKLKKMYSNSIDFGNYDYSGNPNLMSKLKSSDF
                     NVGYHGSLTSDNEKLHFTSDGTGSIIMFTRINTPQLASGKTYTLSAKVRFDEGTTGAI
                     DKLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKGTANVNYQITNLDRFYMSISFV
                     DRDKINGGFKLYDIKIEEGSTATPYQPNLLDDPYWLGKAPLGENIANKSVTFPIKSSA
                     YSLYQANMEEEFVLGQTYTITMKATKPPIQTFIVYNEDSGDYRYGNLEPVEGLVDTWG
                     LTFTPQKVGVNYPKRLTIIQYPQSTTGACQIDWLKIEKGDTRTPNISQFKYFGEGLKD
                     SNNPNDYSWDVTPEYTEKGLNDAVNVYDPQRVEGLKNFADGIQIAGDKVISENDCTVY
                     TLTKDNSQSFIDGYATFIKHGKEVIVNGTVKFKKAYAFGVPLDDEVPDEFVAKIVHGM
                     LTGPSGTSSVSKAMYVRKDLGTIITNSEFAANEWFTFHGNYWVGEE"
     gene            39220..39666
                     /locus_tag="IVW63_000940"
     CDS             39220..39666
                     /locus_tag="IVW63_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859231.1"
                     /translation="MKNIWKYGRTGGEYAGQVLDDMVMTVPFTDVPPLEGIRADGEPL
                     TIADQMFDPKLNQWIVLVNVLDHNDLNNLKAMYESLENENGDLKQLNAKLMLSDVAIK
                     QENTALKEKADGLAQINSKTMLASFQNSKDIAEIKEQLNPASKGGE"
     gene            39668..39805
                     /locus_tag="IVW63_000941"
     CDS             39668..39805
                     /locus_tag="IVW63_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAP7859232.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEAEKIINKDKSA
                     S"
     gene            39842..40135
                     /locus_tag="IVW63_000942"
     CDS             39842..40135
                     /locus_tag="IVW63_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859233.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERSR"
     gene            40158..40355
                     /locus_tag="IVW63_000943"
     CDS             40158..40355
                     /locus_tag="IVW63_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAP7859234.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            40366..41385
                     /locus_tag="IVW63_000944"
     CDS             40366..41385
                     /locus_tag="IVW63_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP7859235.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGPNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPQR"
     gene            41642..42289
                     /locus_tag="IVW63_000945"
     CDS             41642..42289
                     /locus_tag="IVW63_000945"
                     /inference="COORDINATES: protein motif:HMM:NF014505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP7859236.1"
                     /translation="MPNKNYRVYKRGTIVYVDFGVNVGYELSGNHFAIVLNNKDNSKN
                     GVVCVVPISSKKKSNYVSVGKILEVASIKQFISQADKLKEKLRIIILLSLNRGIIDES
                     DLNSFIKDIEAKGEKLSVEEVEKRAVKHNLVCETREQVIKEIKSLSEDMVKYQKVFNC
                     YKKYTQESYVMPLNIQTISKNRIRRINKFDPSGNMKAPGNVLNEVDESLKKYFTK"
     gene            42572..42645
                     /locus_tag="IVW63_000946"
     tRNA            42572..42645
                     /locus_tag="IVW63_000946"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42606..42608,aa:Ile,seq:cat)
     gene            43191..>43760
                     /locus_tag="IVW63_000947"
     CDS             43191..>43760
                     /locus_tag="IVW63_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAP7859237.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
BASE COUNT        15375 a         6996 c         9036 g        12353 t
ORIGIN      
        1 aaataaaaaa agcgttagca actatgctta aaaagcatat cgactgaata aactaagcat
       61 tggacaggct gaaagactac atttaaaatg aaatgcgaag aaacaataga aaataaagtt
      121 gccttagaac catagttgaa tcacctaaca gtcgtgaagg gagaataaga gaaatggcag
      181 aaaaacaaac cgcaggacga gatcaattag gagattttgc accaaaattt gcagaattga
      241 atgatgatgt tttatttgga caagtatggt ccagagaaga attatctgct catcagcgta
      301 gtatcatcac catatctgca ttaatttcag gaggaaattt tgaacaattg ccagctcatc
      361 tgaagattgg caagcaaaat ggcattacta gtgaagaaat agcagaaatc attacccatt
      421 tagcttttta tgtaggatgg ccaaaagctt ggtcagcttt tagtttagca aaagaaatct
      481 atttagaaga aaatagcgaa gataagaaag aggcgtaaat gacgacaaaa cacgaagaaa
      541 tacacaatgg cgtgattttt ccagcaggtg aaaaaaacga agcttacgct caagtattta
      601 ccgggcaaag ctatctgaat atgttagtga atgatcccga agtttctgtt ggtgtaggta
      661 atgtaatttt tgaaccaggt tgtcgcaatc actggcatgt ccataaagac ggctatcaaa
      721 tcttacttgt gaccggagga gaaggctggt atcaggaaga aggaaagcca gcaagacgat
      781 taatggctgg agatgtcgtc gtaacgcaca aagggattaa acattggcat ggtgcgacaa
      841 aagacagttg gtttgaacat ttggcgatca ctgctggtaa ttcagagttt ttagaacctg
      901 taacagatga agtgtatgaa ggattggaaa atcaataatg tcaagcttga acagctcctg
      961 aaagtagatt ttaatcgaac tttcaggagc tgcttttttg attcagtctt ttataaatag
     1021 aaaatagggt taataatagg aatgagaagc acgtcgaaag atcttaatat tgataatcgg
     1081 ctgggcatac atgatttcca cgtcatcaat caaactacct aacagatgat aatcttcccg
     1141 atcatgtcgg ggattaccta atagttcttg atagtagatt tccatactag ggtcccgagg
     1201 attgttcagc aaatcagcaa gtacatctaa atcttctggc tgagtttctg ccgtaccctg
     1261 tatctctatg aaaagccctt cctcagcaaa ttctactcca atacgtattt cagttatttc
     1321 atgggaatat aaataagtaa gaagctcatc gatgattctt tttgataatt ctttttccaa
     1381 gtgtcttttt ttcctttctg acagcggtaa agttatctag tatcggtaca aggatacctg
     1441 caacgaaacc agttgaaaaa ccactgttat atagatttag tcctccgtgc aaagtgctga
     1501 cgttatggac aagagcaata tgtagtacac cagctattac accgtaaaaa ctgccgtaaa
     1561 aaccgcttat gggcgcgaga cctgtcccaa acacagctgc aacaagcatg ccagtactgg
     1621 tgatctcatg aaaagttcca aacaaagaag caataaatat tccgactagt atcggaaaac
     1681 tgttttttaa atgacaacca aaagcactga aacccaccgc agataaaata gcaccgatga
     1741 caggtccatt taactgaccg ccaaccagca aaacataaga agacagcatc agaccaacta
     1801 agcctatgtt gatcaaagta gcaccaatac cagaattagc aatgaaatca gttgtcaatt
     1861 ttccagatga atcgaaaatt tctcgaatcc ccaaaagccg aaaggaatta taatagaaac
     1921 caattccgac tgtcagcgaa aaaaagccaa aaataatcca aatgagagga aagtgatatt
     1981 cattgaaaac caatgtattt tcgacgattg aatagctgaa taacctcaaa acagcagtaa
     2041 aagtcatcgc aatcaaccca gaggtgaatc caatattata aagtgtgaat ccacgatgga
     2101 aaactaaagt ttgagcagct aagggcggaa gaagtagacc aattgctatg ccagctaaat
     2161 tccccaataa aatacctatc agtaaaggaa aacgcatacc aaaagtgata taactaacga
     2221 ccggtgataa tgcgctacca aacagtccga tcatgatgta ctgagaaaaa ggtttattga
     2281 caaatacagc gtatagatac acacctaaaa tgattgagat agaattataa aggtttttgc
     2341 caaaaaaaga gaaaccagaa tcgaagcaaa taagggaccg tttaaaatca ccttgtgccg
     2401 ataagctaaa agcacagaaa gtaaggtcaa aatccctaca tttatgaatg cgcttccgaa
     2461 accgcctaaa gcaaaataat ctgtcaaaag attgcttggc gaggtaagaa tagttagcaa
     2521 tccactccaa ttatcagtag gagtattaga aagcaagcca ataaaaagaa aaaaaacacc
     2581 tgtaaaacca agataaaaat actttctttt ctgtgaaacg attcgttttt gaggatgaat
     2641 ataaataacg tcagtttcgt tttccattac acaccttctt tttcattttc tttaactata
     2701 acttgaaatg aaagatttgg acaactatca tttaggtcaa aactaaaaat gtaagggaac
     2761 ccattgaatt taaccaaatt tttttaattt tgcaaaaaaa agttaaagaa gactgaaaaa
     2821 aaatttaaaa tataacgttt tgagtaaaat gtttgcaaaa aatgctaaaa atagggtaca
     2881 ataaaacaac atatactgca gtaaagaagt gggggagttt taatgagaag aaaagtctat
     2941 accaaggatc aaattctaaa agctgcttat gatgttgttg caaaggaagg gtttaaagga
     3001 tttactgcga gaaatattgc taaaaagatg gggatttcga cacagccgat ttatctggaa
     3061 ttcaaaaaca tggaagattt aaaaaatacg ttgctggatt ctatctttga acaactaaaa
     3121 gaagatgttt tccctattga acgtactggt gataaaatca ttgatctcgg tttgaactat
     3181 atctactttg caaaaaagca tcatagtctt tacatggcat tgtacattga tgaacatggg
     3241 gacggaaaga aaatgcatga tttttcatac aattatttcc gtgaaatagt taaagaagat
     3301 gaaagataca atcaattatc ggatgaatat gtcgatgctc tgcatactgg tacatgggta
     3361 gcagtgactg gcttagcgtc attgatgtca tcaaacatca tgcatccaac agaagaacaa
     3421 atcattgcac tgatcaaacg gacaattgac tcgattttag cattagataa tcctgaaata
     3481 atcagatagt gttctatcag tatgaatttg atcggtaagt ccgttggctg caaactgtca
     3541 atggactttt ttgctaaaaa aagcgatttc tgttatttat ctattagaaa taggcttgac
     3601 atttcgtgaa aaaagtttaa aaatagtact tacggaaggt tggcagagtg gtaatgcacc
     3661 ggactcgaaa tccggcgaac cggctaatac cggcgcgcag gttcaaatcc tgtaccttcc
     3721 ttatatatca acgattagac acgatttcga tcgtgtcttt tttgttgtat atttagccta
     3781 aaatgttttt tgactcccct tttgactccc cctgagtact gttcttcata aatgctacaa
     3841 aattattgat gacttttttg ttttgagttt cagttacatg agtgtaaata tttgaagtag
     3901 tttgaatgtc tgcatgccct aaacgttcct gaacatcttt taaagaagct cctgattcaa
     3961 aaaggagaga ggcatgagta tgtcgaaaac catgagtagt gattctttta gtcaattctg
     4021 gatgatgctt atatatgaca ttaagccacg aacgtgaaac tgtagggtta tagagaagac
     4081 catcatggtg aaaaattaag ttttcccttt ggattgtaac gatcgttttg ttttttgtat
     4141 aatactttct caataaactg atcaaatcat tgtccagata aatttttctt tttccagatt
     4201 ttgatttagg agtatttacg atcaatcttc cttgataacc tcttgttaca gttttattga
     4261 tattgagtgt tttgctctta aagtcaatat ccgaccaggt cagagcaaaa gcttctcctt
     4321 ttcttatacc tgtaaaagcc aatagggaaa agaataaata tctttcatca tcatcgtttc
     4381 ttattgcttc taaaaatttg attaattctt ctttagtata aaattcgata tttttatctt
     4441 cgatatctag agcttctcca cgtggaatag aaactaattt cataggattg ctagttataa
     4501 tttgtaaaga agcagcgtaa tcaaaaacat tagatgtgta attttttatt ttcttaaaaa
     4561 ttttaggatg gctatcggac caagtgttta ctgcttcttg acagaaaaaa acgtctattt
     4621 tgtcaatgaa cttatctcca aacactttta agatgtgtgt gtcaaaaatt tgtttggtgg
     4681 aggaccaagt gctttcttta actgtctttt tataattttc aaaccataag ccgtaaacat
     4741 attcgaattt cttgctcttt tgagctgtag aagcttgcag tcctttttcc tgtatatctg
     4801 cctccaatct ttttaaagct ctctcagcgg ctaatggcgt actaaaacct cgtctcgttg
     4861 tttttctttt ttttcctgtt agaggatcaa ctcctaagta cagactaaac tgatattttt
     4921 cttcgccttt ttttgttaag tgctttttaa ttcgtttatc aatttctttt tttgccatct
     4981 ttatctttcc tttcgtacgt ttgttcggtt gtacagcgga tttcgagatg gtaaaatagg
     5041 gtacaacaaa tagacctact ttaccgtagc tctttgcaca tttgcgttct tggtcgggcg
     5101 gcaaatgtgc tttttttatt tcactcttag ttcttgtcct ggataaagca tgtagttgtt
     5161 tggatccata ccgtttaatg caaacagttg atctaccgta attccagctc gttcagctat
     5221 ttgtttggtc ccttcaccag gttgcaaagt caaggtttcg gtttcagatg aagaaggtgc
     5281 cgttggttga gcttgattag ctggtacata atcttgtggt actgattgct ccgttgaact
     5341 gggagtgggt gaaacttgtt caacacttga actaggagta gcttctgcat agttttctac
     5401 actttcagca gagtaagtac tactagtttc aggaggcgta ttctgcgcaa tagcagcttg
     5461 ttctacagta ctagaagatg caatagtact ttctgttgta gtcgaagatg attgttcgtt
     5521 gctacttgtt gagctagtag ttgttctaga ttctttagtt tttttccttt ttgtagggtt
     5581 tcaaaactaa tttctcatta tcatcagatt tgttaggctt ttctggagtt aaaataatat
     5641 ttttatcttc tttgctgaca gtatatttgg catcattatc tttgtcttta tcatctttcc
     5701 aagtcataac atcgccttca agtgtatact caaatttgta attcatttgg tcgactaagc
     5761 ttttagcaaa ttcttctccc atagcctccc aatcgttact tgaagttgat ttcatagaac
     5821 ttgtgtcaac actaaaagat acgacgtgat cagaaaatga tacgatcata ttaggttcgt
     5881 catctttggt tgcttcaatc aaccaatcat tagcttttaa atcttctgta gttacttttt
     5941 taccacaagc agtgaaaagt aacagagaag caaaaactaa taaacttgtt attacttttt
     6001 tcatttttta ttcctcattt ctatgatatg atttttattg gggaatctta gaaataaggt
     6061 ttcgagtccg tgttgctgca cgggcttttt ttatttaaat aaatcccaaa aactgaatgt
     6121 agttttcttg tatactttat tgtaagcagc cttttttggg tctttaatcc agccgctacc
     6181 ttttttccca taaccaggaa taactgcttt ttttactttt ctttttgctt ttccagtggt
     6241 tctagcgctt atggattttt ttatacttgg ttttctcatt cctattttca tctatatcct
     6301 ccttacgttg tattataatt cacaagaaac gatcgaattc atctggtaat ccaaagcaga
     6361 cgagcttttc atattttgtc atatgatcaa agccgtctaa agttggatca atagtcagat
     6421 gagttgcgaa ataatttgct tctttttcaa tttttaattc agatactagc gtttttttag
     6481 acaacatagg tgtgttttca ttcggatgca aaacacagtg gcctaattca tgactacaag
     6541 ttatccattt tcccatctca tctaaactag aatttatgtg gatcattttt atctgtttga
     6601 atttactata gtaaccataa atttctccca aatcttcttc taaaactagt atcttcaatt
     6661 ctcgtgcaat tctaaaagga ttgcgtgttt gatatagttt taccagctta ttaattttgt
     6721 tatcaatttg aggtaaatac ataaacaacg tactcctttt aatcgcgata ttttttaggt
     6781 gtgtattttt tcttagcttc tattttagct attcgcaaag cattctctaa agaaataatg
     6841 agagcttcac gtgtcgcttc actcatttca ttatctttct tcgaaaaagc cattccatca
     6901 gcattagata aatcgtcgat taatgactgc aattcttttt ggatatcacg ctcgtctttt
     6961 tctgttaaat catagtatct ttttttctca gtacgtccta gcaaataatc tacagatacg
     7021 tcgaagtagt cagcaatttc ttgtaacttt tcggcagttg gctgttttcc tgcgtttaaa
     7081 ctataaaagt aattctctcc gtacttcaaa tctttagcga cttgttgaag gtttttattc
     7141 ttgtttttcg ctagttcttt tattctttca aatgttgtca ttccaacgtt cctttccaac
     7201 acgaaaaaat aatttacgaa aaagagtaaa aatagcttta caattttacg atatagagtt
     7261 attatttatc cgtaagttaa tttgatagaa aaaagcaaac taaaaacaca ccttatagca
     7321 taaagtttgg cgaccaagtg caaataaaag gttttgttat aggcttattt ctctatgtat
     7381 tcattttact ctatagtgta aaaatgtcaa tggaaattat attttttcta tcattttaac
     7441 ttacaaattt ataaaaaaag gaagtgggtt aatgtcaaac ttggataacg gtcgtgcggc
     7501 gatcaaagag tttatgaaag agaatggaat aactatggat gatttggcta ctgcttatgg
     7561 tcacacgcgt gtacgaatgc aacaaattct tgatggacac tggagtggac caaaggcaaa
     7621 cagaactatt ctagagatca tccgtgatta cagaattcga taggaggcaa gtcatgaata
     7681 ttctaagcga agagtttttg actcgtttaa gaattgcaat tgttgaagtt gtaaaggacg
     7741 cacttagtca actttcaaaa aagaatttgt cagaaacacg atatttaaaa aagatcgaag
     7801 ctagaaaata tgtgggaggt gtaaacgatc aaggttttga gaagttaata gctcacggtt
     7861 taaaagaaat tcgtatagat ggctttttaa gatatgacaa aaaggacatc gatgaactga
     7921 tggctaaata caaaatttaa aggaggtcaa catgggaaag tttaatcgaa cattagtatt
     7981 cagcgcgcca ctaattatct acgctttagg tctatggggt agtagacaag cattaatcgg
     8041 cacgatcgtt tacatgcttt ggattttcat tgggcttgat gaagctgagt acagagcgaa
     8101 aaagccagtc gggagggact gactaaaaaa gtctaatgtc tataagaaag gtttgacaat
     8161 aaatgaaaga attatttttt ttaataactt tcatcatttt ttctatcagt gttttctaca
     8221 ttaacctttg cgttgctaga tttgctttga aaagttttag gaacagcaaa cgaaaataga
     8281 gctataaaag atacgaatgt agtagctacg ttaaattgct ctttagaaaa cgtcaatgtc
     8341 attggaatga taattgatat cgatgagaaa atctttgcga taataactat ccatttttca
     8401 attataaaca tttttaaatt aagcaccatt agacaaaatg tagttcctat atagaggata
     8461 aatgaagata gaaataaaca tattagtcca gttttaaaaa aagagaagta atctatgtgg
     8521 gcaaattctg ttaatatgct tttttgattt aacacaatca aactactgtt ggacaaaaat
     8581 gacagtaagg aaagagttgc tccgattact aaataaaaaa tagttgttaa caatattata
     8641 ttatcaattt ttctgctcat gttttcaccc caccagaatt atatcaaaaa ggagagaaga
     8701 aataatgcaa gaattagtaa ttttgaaaaa taaagaagct gtgactacga gcttacaagt
     8761 tgcagaaagc ttcgataaaa agcacagaca tgttttgacg gctattgatg aactaaaaga
     8821 gggggttgcc gaaaattggg cagacctatt ttgggaagat acttatgttc atcctcaaaa
     8881 taaacaatca taccgaatta tttatatgaa tagagacggc ttctctctat tagcaatggg
     8941 cttcactggt aagaaagctt taagttttaa acttcaatat attgaggcct tcaacaagat
     9001 ggaaaaagaa ttaaaagacc aattgccatc aattccagca actaaacgag aaatggcatt
     9061 acttgctcta gctgcaaacg aagaaacgaa tgaaagagta gacgctatcg agtctgattt
     9121 aaacgatttg aagaacaatc aacttctagc tgaaccagat taccgaacaa tttctaatat
     9181 ggttcgcaac aaaattagag ttatttgtaa tcagcagcat ttaaatagca aagcaaaagc
     9241 agaattgttt aaagacttga atggcggaat taagcgaatc actggagcag tagctagaaa
     9301 tcgtatcaag gcaaaacagt tcgatgatgt tatcgatttt attaacaatt ggatgccttc
     9361 tacagcgacg atgacaatta ttaagcaaat ggagttgtta gaggatgaat agagctgaag
     9421 cgctaaaaat aggcgtaata attgctaatc gctggtggag acacaataaa ccaaacatcc
     9481 taagccaaca acatattgat aagcaaaaag catggcaaca aataaaaaag tgactcagcc
     9541 gaccaaagca atgagtcaca aagaaaatac atctaaggag atgttaccac atgaaaaaag
     9601 aactttccac tctagatcaa tatttgactg atcctagttg gggcaaatcg aatatcaagg
     9661 aaacaagcaa tcgaaaaatc agacgtaatc ttttgacgga tgaagaacta gcatgtgatc
     9721 aagacgattt gggaaatttt gtgagtattt gggatcatgt ctatcttatc catttatcga
     9781 ggaagtccaa aaaaactgaa tatatctatg tcatcgaaga tggcttgatt gatgcgctag
     9841 aagagtatga cagagataac ttgattgata tctcttatta cggatcaggt aagaaataca
     9901 ttgctgaaat ggaggcagaa tttgatgagt gaaaaggaac aacctttgaa aaatagaagt
     9961 gataatacgc tttttaatac cttatacaaa ataaatgtga aagatgttac tgaaaaacga
    10021 aataacctca cttatctttc gtgggcatgg gcttgggcag aagttagcaa agtgtgtgag
    10081 gcagtagatt atgaaatcta tcatgatcca gaaacatatc tgccgtatgt ctttgataag
    10141 aaaacaggct atatggtttt taccagtatc acagtcaacg gagtaaagcg tgacatgtgg
    10201 ttaccagtca tggatggtgc aaacaaggca atgaaagatg agccatatac ctacgaagtc
    10261 aatgattatc agtggaataa cgaaacgaag aaaaaagaga ttgttggaaa aatcgaaaag
    10321 cgagttgaag cagcaactat gtttgatatc aacaaaacga tcatgcgctg tcttgtaaaa
    10381 aatctagcaa tgtttgggct agggctatat atatttgctg gcgaagatat gccagaagat
    10441 gtctcgatgc ttgaaccagc tactcaaaga agcaaaaagc tattcttgga tgctttacaa
    10501 ctggttgcta acaagtacga aaaatcaatt gatgaagcaa ttgttgcatt gactgatgcg
    10561 gcttctataa ccgctgatga cagtaaatgg accaagagag acttgggcat tctaaaacga
    10621 ggcgttaact ggattgaaga tcagtacaga gaagaaacaa aagagaagtg atatgagtgt
    10681 ttaaaccatt gatcgattca tattcagcgg ttctgaaaaa gttcaaagga aaagacatag
    10741 gtgcaacgat caatgaagaa gtgaacattg atcgactaaa gacgatgtat gacggatatg
    10801 atggcgatcg gattattgaa gttcgattta ttgatccacg tcgatttact gtgcagcaac
    10861 gaaacttcat ctatgcgctg ataggcgata ttttcatcga tacaggcatg ccaacggact
    10921 tctggaagga attcttttac ttccgttttg aaggcgtcac agggcgcaaa ataagcctca
    10981 aagacgaatc gaatacaact gtgagtgatg ctaatgtctt agcaaatatc atcttagatt
    11041 tcatctttga acatcatatt cctttcaaag aaggctatga gattttacca gcgaatcaag
    11101 aatattactt ctacaaatgc atcacaaaaa gagtctgctg catctgtggc aaaacaggag
    11161 ctgacatcga tcactttgac aaagcgctag gaagacgaaa gcgcaaagaa gttgatcatt
    11221 cagagtacac atttgcagca ctctgcagga ttcatcacac ggagaaacac aatataggtg
    11281 tgatcaattt caaaaataaa tatcaaatca aagggatcaa gttaaaccag gaaacaatta
    11341 agaaacttag aataggaggg taaaaaatat tgtctgacaa caaacgctac tactatttaa
    11401 aactaaaaga gaattttttc gatagtgacg agatggttct cttagaaagt atgccagatg
    11461 gctatattta ttctaatatt cttctcaaac tttatttaag aagtctaaaa cacgaaggta
    11521 agttgatgtt taatgacagg attccattta actctacaat gctcgcaact attacaagac
    11581 attctgtagg agtcgtagaa aaagcggtac aaattttccg tgatttgcag cttattgacg
    11641 tattagataa cggagcaatt tatatgtctg atatacaaag tttcattgga aaatcctcaa
    11701 ctgaagcaga tagaaaaaga gaatacagaa agaaaataga agaggcaaaa cggaatttaa
    11761 taactggagg acaagtgtcg gacaaatgtc cagacaaaac tacaccagag ttagagatag
    11821 agatagagaa agatatagat atagataaag aagaaaagaa aggtaagtat tctgacgaac
    11881 acttacgcct tgctaaaaaa ttgcaaagta atttaactga agattttcca aaagaaatga
    11941 acaaagtaga tatcgaaaaa tgggcagaca caatcaggtt gatggaagaa agagataaag
    12001 cgtctataga agcgattgag tatgtgatca attggctacc tacaaatgaa ttttggtttg
    12061 gaaatattag aagtgctaag aaattgagag aaaaatttga gaagctcaaa ttcgaaatca
    12121 aagcagacaa gaataatcat aaaaagcaaa gtcaaaaact acagtacagc aatcctagtg
    12181 aatatgacga cttgccaatt taaaaaggag atgcatcaca tggaaagcct agcaaatgct
    12241 atggagaaac taataagaag agtattagtg caaagcggga aatgtccaga atgtagcgaa
    12301 cctttgtata gttggcgagc taaaaataag gatggttcag aacgttgtaa accaacatgc
    12361 atgagttgtg gttataaagc gttacgtgtg aaagaggata tacagaccga acggatatat
    12421 aacgacagct taaaagcacg agcgttgagt ttttttcaaa atggttcggt attaacagat
    12481 aaaactttgt ttaaatgcaa aatggagaat tatcacgtag tggaccaaga aacgaaaatt
    12541 gctttagaaa gagctaaaag ctttgtaaat gatgtcttac tgaaccatcc tgcacatttc
    12601 attctatcag ggaaatcagg aagcggaaaa agccacttgt caatggcgac agcttgggaa
    12661 atacttgagc gctcaaatta tgacaagaaa atacttttta taagctatca agagttatta
    12721 gagcaaataa agttttctta taacaatgct gaactgagaa aagaaattga aggatcgctt
    12781 atagccgata tcaaaacaac tgatttggtg gtttttgacg atattggagc tgaattaggt
    12841 agcggggtat caaatagtag gcagtttaca aacaacacgt taaacacgct cttagaagcc
    12901 agacagaaca aggcaacgat catcacaaca aacttatccg gtcctgaact aagagaagcc
    12961 tacggcgaaa gaattgtttc tagaatattt aagaattcag aaggttatgc gctgaaattc
    13021 caacaaacag cagacaagcg cataaaacca gtgaaaggta gtatcgcatg aataaatacc
    13081 gtaataagaa aactgttcat cgaggtatca agtttgattc tatcgcggaa gcagagtatt
    13141 acgatttagc cttgtggcaa gcagaagcga acggctggaa agtaaaactt caggaaagat
    13201 ttgagctgat gccgaaattt gaactagatg gaaaaaagta tcgcaagatc gagtatattc
    13261 ccgacttcac attttataaa aacggcaaac ttgtcaaagt cgtagatgtc aaaggaatgc
    13321 agacaaaaga ctttaagatc aaggcaaagt tgttctgtca tcaatatcaa gtgccgttga
    13381 tattagctaa aaaatatcgg aatacgttca aggaagagcg tttttaacga ggtggtccat
    13441 catgacaaca gaagaagtga ttcaaatgcg tattcgaagc cttcaacgtg agattgacga
    13501 tctggaacgg ataaaggcag tgatggtcaa tgaaacggcg agaaaggcaa tcaatttgca
    13561 catagtgaat ttaagaaggg aaattcgtag attggaggaa tgagcgtggg taagaaagca
    13621 gcaatgaaac gaatcattga actgacacat tctgagaatt ggcaagaaga caaagaaata
    13681 gttgcagaag tccaaaagct cggtaaatca atgtggactg aaaagcctaa acggaaaacg
    13741 ccgagaaaaa ttgcaatctg gcatggtgat cgaattctag taacgggtac agctgaacag
    13801 ttatctgaaa ttactggact gagcaaaaac atcatctggg atagagctag gagcttatgg
    13861 attgattcaa aggggcgaca gtttaggtat gtggaggaga aataatggat ctcattacac
    13921 aatacagtga tatcatcctc aagaaaatca tgatgaagat tcagaaagat aaaaaagcaa
    13981 aagaacgagc ggaattagtt aagttggaaa tggctgaaac aggagcagga gtgcgaagta
    14041 gcaggcattg gaaagcagca gcaaacattg aattttatta caacgaaatt caaaaagggt
    14101 tcgatcagat gcgtgagctg gatcggcaaa caaattggag caagaaactt catcaggatc
    14161 gtttcaaatt tgtagaaaag tatagagaga tactgaatga gtatttcgag gaggactaga
    14221 tgtttaattc aacgttagcg tcaattcact ttttattcta tataacgata tttgtagcta
    14281 tattaattaa tgcgataaaa agcggttttt taacaccaat cggcacaatt ttaacattag
    14341 cttcatttgt tacaagttgt attatccaac ttaaatatat aaaggagaat gaataatgga
    14401 cgaactaatc acaaaagtag agcagtgggc taaagataag ggattggatc aagctgattc
    14461 cagcaagcaa atgttaaaaa cgatcgaaga gatcggggaa gttgccgctt ctctagctag
    14521 aaaagatgaa catggtttaa gagacggaat tggagatgta gtagtaacct tgattatttt
    14581 agctatgcaa aatgatatgg atttgtacga gtgtctgaac caagcataca acgaaatcaa
    14641 aggacgcaca ggaaaaatgg tagatggtgt attcgtgaag tcgagtgatt tggaggacag
    14701 caaatgatca gcctaacaat attttggtgt gtaattggcg gcttactagc gatgttagga
    14761 gcatacctca tttacgagag tgcaaaaggc aaaaaatata cagcagtagg gattattttg
    14821 tttgttgtcg gaattttagt tgcgattggt gcagaaataa atctttattt aaacggtacg
    14881 acagaagagt tgatgtggtt tttattgtgg acaaggagat aggaggacag cgaaatgggc
    14941 gatatgggcg aatactggaa agatattaaa ccgcatctaa aagaacgtag aaaacaacat
    15001 gtcagaaaga tgggcaattc agcaactaaa aatattgaaa ccttgggatt tgaatttact
    15061 cattatccaa acaatcatca atttgcaatt aatacccata atggaattat tgactactgg
    15121 ggaactacag gaacgtggat tgagcgcaaa acaaaaaaac gtggtaaagg gatacgtagt
    15181 ttgaggaaat atattaatca ggaggacagc aaatgaacta tacacaacaa gaactgactg
    15241 atttatgtcc aaaacatgta gctgagttca tcaataatga agtcctgcct aaatatgcag
    15301 atggtttaaa tacagcagaa aacgttacag attttatgat taatgatgct attgatcgtt
    15361 tgatattttt agaaatagat tgtattgctt attatcgtct acacgcagaa gttgctttga
    15421 ttgatccgta tattgcttta agccaaaatc gaaaaatact cgtagcctat attgatacca
    15481 aacagatttt agaaggcaga gatgtcgaga tagagatcga tgaggaggaa gtgggatgaa
    15541 agcatacaca atcaagtttt atggaaataa aacctatgta tacatcctaa gcggtctcag
    15601 acttgatttt agaggctatt caaaagaaga ccttttagaa tccttatatg gttacggata
    15661 tttaaatgaa gatgaactaa taagcttaga gaaatttaca aatgcttgga cgattgagga
    15721 ggaagcagaa tgaagattta tgtagtaaag ttcgggaata aattttatag aagtgatgaa
    15781 cgctctatag gggctaacac attattcatt gtagacatac tccaaagtgc gagatggttt
    15841 gatagcctcg aagaagctaa ccaagtttca cgacgacttg gtggattaac acaagtatat
    15901 gaactggtca ctgtcgatca tgaggaggta gaaagatgaa attaaaagac ggattttacg
    15961 ctagtagtca tggtatcggc ggtttaatgc tagatatgcc gacaaagaat cctaaaaaac
    16021 gtaagaaacc aaaattcaaa gtcggtgaca tggttcgctg cgaagcagaa gggttcatct
    16081 atccatttcg tggatatgta gaacacgtct ataatcactc agcgatcatt cgtattgaaa
    16141 acacgatgga atgtgataag tggttagcga aaagcaaaga gaatttagct gtagcgagat
    16201 tggtggatat gaaggctata taaacagcga aaaaatgtac ttctaagaga aaaatttatt
    16261 ttttataaaa ataggaaagt atcattatga aaaagaccac agagataaat aaacctacca
    16321 cataaaaaat gaatatttct tgcgattcaa tataggtata tttaacaatt tgtacaataa
    16381 aaaatactat aggtaaaaaa gataacatga ggagcttatt tgttctagag tgtttgacaa
    16441 agtaacaaaa tgcgacgata ccaatacaaa cgggaatcca aaataacagc atgctccaca
    16501 tagtcactca accatctcct atacgcttta ttatcaatta gataatatca tttttcgtaa
    16561 taaagataaa aaaataagta aggcttctca ttaaaatata aaaaagacag ccgaccactg
    16621 gctgtcctta gcagaatatt gaaatagtga gccatctgtt ttccgccaga tagctcaaca
    16681 tgtatatggg taacgagtgc aacctcgcta cttgaaaagc ttagcataag catgggtata
    16741 aaaaaagccg gattcctccg accttaatta ataattctga cacaattatt atatcataaa
    16801 tggaggaatc aatggatggt acttttcgat gtaaagaagt atgagacacc agaggcaaaa
    16861 gatgtggata tggatcgcac aaaacataat gttggtgttt ttctttcagc atatctgtca
    16921 gctagatgta ggataggtca acctcgggag cctaaagtaa cggcatctta ctccttggtt
    16981 ccaccttcta cagcaaataa tacatttgaa gcagaacgaa tgatgattga gagagaggaa
    17041 gcgcaagaag aatttgagta cttgcacaaa ttatttgttc gtggctattc agcaattcag
    17101 catccgcata aacctgatgt aacagaaagg cgcaagaaga tattctatga tcgttatatc
    17161 aatggtctgc ccatttatgt aactgctcaa aggaataata ctagcgaaga atcggttaaa
    17221 gtagaatcaa acagaattat catccaattt gcttcatcgt tagaactggt tgcttttaag
    17281 tagccagttt ttacactttt tatacccttt gattacccat ttggtttcca ttttatacct
    17341 tttttatacc aatcacttac ctggtaaatg atttattatg atagtgtcga aagattagtg
    17401 ataggtctga gacaaaataa taataaaagg aacatcgttt tattattgtt tcacaattaa
    17461 gcttcgatag acagcaacgg aaatattaag aataaggatg tgaattccaa ctccttctaa
    17521 attgttctta ttatctatca tccgttgctg tttattaatt tatgtattgg agggaaaacg
    17581 aatggaagtc gagcaaataa agtatcaagg tatggatcgg gaacggttga ttgatattat
    17641 tgagcaacaa cgtttagaat tgatccaaaa agaagctgta tgtaaagagt acaaaaaaca
    17701 tttagaacaa gtaattgagt atcattcagt agaaaagtac agatcagtgg tgcaaaaaaa
    17761 tagagcaacg agtcctgatc ctcgtcaaga tgtatcgatt agtatcaaga cgccagtatt
    17821 taattctgtt aaatcagaaa agctagaaag tatctcaact gctttggtag aaaaagcagc
    17881 tgaaatgaac tccctagcaa atgaagttag tcgtcttatt tagtcacatc gataacttga
    17941 gagtctttgg tgattccgtt ttttatagaa ttaatggttt gttcagcgga atatttagtc
    18001 aagtatgttt cgctagttgc tactacttca ttgttatcgg acttaataac gaagtaatat
    18061 tggccattag ttgcttctct tataacaaag tacaaatttt tcaccacctt ttaatttatt
    18121 tcagcggacc actcgctgat aaataaaatt atacacttag tatttatttt cacaatatta
    18181 atttgtcact gtggcggaaa gggtagacgc taagcatgtg tgttaggtca atgcttcggc
    18241 aaccatgcaa ggttcgattc cttgccagtg actttggcaa ctgagggttg gaaatgggcg
    18301 ctcaaagtac acgagcaagg cgaggtcgat agtaatcgat ggaatcggtg taggttgctt
    18361 gatagaacta taactgcatc tcgtttatga ggtgtagttt ttacatatta gatcactcat
    18421 cgagtggtct ttttattttg gaaggggagt aaaaaaatga acgaaaacca attaagagag
    18481 ttgtttaaaa cgaatgaagc aaacaaaaca atggaggcga cattctacga aactcaaaaa
    18541 agcttagcgt taatcgcaaa acaagctaag tatttctacg atcagcttat tctgcaagga
    18601 tttaatgacg cacaggctat ggaatttatg atgcgaacct tttctgccag taaccaacag
    18661 aaagagtgat acgtaatgag gaactactgg tatgtatcat tatcaaataa atatccgcaa
    18721 ccaaacgcag atgatccaat tagagttgtc cagtcagtcc agattaaaaa gaagtactcc
    18781 atcattgaaa tgaccagaga agctacgcca aaagagattg ataagtacaa tcttcgttac
    18841 tgcggccatg gatattttag tgagcagaac atacagacaa atattgagag atattgttaa
    18901 taaaattgaa aggtggtggc ttgaatgtgg taaatttgac accaaaacaa aaagcttttg
    18961 cggatgaata tataaaaaat ggtggtaatg ctactcaagc cgccattaaa gcaggttata
    19021 gcaaacgatc agcaagagta ataggtaagg aaaacctaac taaacctaac ataatacagt
    19081 atattaatga acggctaaat cctatcgaaa agaagcgcaa attaagtgcc gaggacgctt
    19141 taaatgaatt gatagatatt tggcaaggag aagtacaaat aagcgtgagc aagcaaatag
    19201 accgcttgga gaaaaacaag gttattaaac atatgcaata tgaatataca ccagatttag
    19261 aaagcaaatt gaaagccttg gatttgtatt tgaagtataa atcgctgtta tcacaaacgc
    19321 aattagaaaa agctcaaaca gaaataaaat taatgcaagc aaaattagaa caattacaga
    19381 taaactcaga gcgttctacc gaagaaaaac ttgatgagtt gttagaaaag attagtggtg
    19441 aattagatgg cactagttga tatttataac ccaaagcaaa tcgacgtgtt aaataaaacc
    19501 attaagaatg attggtttat tactttatta catggagcaa aacgttctgg aaaaacaaaa
    19561 ataaacaatg atttgttctt gtttgaattg cgacgtgtgc gaaagattgc cgatgaagaa
    19621 gacattaagg aaccaatgta tatcctagca ggagtttcaa gtgcaacaat ccaaaagaac
    19681 atcttacagg aactatacaa catgtacagc atagaaccta aattcgataa acatggaaac
    19741 tttaagctat ttggcgttaa ggtcgtacaa gcttatacag gaaacattgg cggtgttggc
    19801 gcaattcgtg gtatgacagc atatggcgct tatatcaatg aggcatcgct agctagacaa
    19861 gaagtatttg ctgaaatcgt ttcacgttgt tcaggaacag gagcgagaat actagctgat
    19921 acaaaccctg acaacccgga acactggcta aagaaagagt atatcgacaa ttcaagcaaa
    19981 aatattcaat cgttccactt tgaattagat gataatacat ttttatctga acgatatcgt
    20041 aacaatatta aagaatcaac accaagcggc atgttttatg atcgtgatat caaaggttta
    20101 tgggtttctg cagaaggtgt cgtttatcgt gattttgatg ctagcaagca ctacatccag
    20161 tcaaaagact taccaccttt gagcaacttt tattgtggtg ttgactgggg atatgaacac
    20221 tggggttcaa tcgtagttat aggtgaaacg gatgacggaa cagcttattt aatcgaagaa
    20281 catgctactc aatttgaaga gattgattat tgggtagatg tggcaaaagg cattcaagag
    20341 cgttacggct tacgagtacc tttttattgt gactctgcga gaccggagca tgtggctagg
    20401 tttgtaagag aaaagattaa tgctaaaaat gctcataaag cacggttatc tggagttgag
    20461 gaagtcgcca agagatttaa acaagataaa ttgtttatct gtcaagatag agtgatgaaa
    20521 tttcgggatg aaatttatca atacatttgg gacaagaaaa aaggcgagcc aataaaagaa
    20581 tatgatgatg tgctagactc cgttcgatat gcgatatata ctcatgagct tcttaagaaa
    20641 ccaaaagtta atgtcaacga aaagattaaa cgtattaaac gcatgtttta aggagtgtga
    20701 aaaatggata aggtaaacga gtttgaatac ggagctgata tacattattc taatgacgtg
    20761 aacacaaatt atgtaaagtt tagcgtagac tcaaatcttc actatagatt tagctcagca
    20821 gaagatttac ttaacgattt agatacttta gcagcaatga taaaacatca tcatgaatat
    20881 caggtaaaaa ggctaagtgt attagatgat tattataaag ctagaaatac aaatatcatg
    20941 gataaccgta ggcgcagaga aaaagaaaaa gcggatcacc gatcagcaca taactttgga
    21001 aaagttcttt gtacgtttga tgttgggtac aacacaggca atcctataaa agtgcaaatc
    21061 gaggacacaa atcaacaaaa agaaatcgaa gagtttaata ctaataatga catagatggg
    21121 ttaaatgatg aactctggct tgatatggat aagtatggga gagcctatga gattatctat
    21181 cgagattcag atgatacaga ttacgttgat ttggctaatg tatttgaaac gtttgttgta
    21241 tatgatacta cagtaaaacg agagcctatt ttggctgtac ggtatcctaa gacaagattc
    21301 aacaaggatg ctgataaaca gtacattcaa ccaatcgtat acacaaaaga aaaaagtatc
    21361 acttatgatg agacgacact aacagcaatt gagttaaaga atccccagga tgaaccgcat
    21421 gaatataaag aggtacctat tacagagtat tctcctaatc gttttcggat gggcttgtat
    21481 gaagatgtac tatctttgat tgatctatac gatgcagggc agtctgatac cgccaattat
    21541 atgactgatc taaacgatgc tcttctagtt attagtggtg atattgaagc agcaggacta
    21601 tccacagagg acgccatcaa gcagaaagaa gcgaatatgc ttttgcttga gtctggaact
    21661 gatgtgaacg gtaataaaac aagtgtgact gcaggatata tttacaaaca atatgatgtg
    21721 aacggtgtag aagcatacaa atacagagta cgcaaggata ttcacgaaat atccatggtt
    21781 cctgatctta ctgatgacaa tttttccgga gtgcaatcgg gagaagcaat gaaatataaa
    21841 ttatttggat ttgaacaaat gacggcaaca aagcaaaggc tattcaaaaa aggccttatg
    21901 cggcgttatc gtcttttatt tagcctaaaa tcaagtattt ctgaaatgga taactccgat
    21961 ttgaaaggct tacgtgtaat atttacgcct aatctaccta aagccattct ggaagagttg
    22021 aaatctttgg ttgatgctgg agctgaactc agtcaagaga cgatcttagg actcgcttct
    22081 tttgttccag atgtacaggc agagttgaaa cgagtaaata aagaaacgca aaagcagatt
    22141 ggcatttttg attcagatgg tgaagaagta attaacaaca aaaaagatga aacagggggg
    22201 tgattaaatg aactcccaag aatattggat caaacgggaa aaggaatggc aaaagcaaca
    22261 aattaaagat gataaaaagc gcatggcaga aattaaaagt cgcatgcaat acgcacaaga
    22321 tgcgatacaa aaagaaatag acgcgcagtg ggacagtttc tccaatggcc agaaaatcac
    22381 tcgtagcgaa gcgatgaagc gtgctagtga aatggatgtc aaagcattcg ctcgcaaagc
    22441 aaagaagtat gtcaaagaga aagatttttc tcctacagca aaccaagaat taaagctata
    22501 caatcttacg atgcgtgtaa atagattaga gctcttaaaa gctaatatcg ggcttgaatt
    22561 gatttcactg tttaatgaat tggataagta cttttcgaat gaattaacaa aagctggttt
    22621 agctgaattg aagagacaag ccggtatttt agaaatgact attgcttcaa gtggatatgc
    22681 aaagctgata gaactagtaa taaacagctc ctttttgagt gatgacgtgt cttttagtga
    22741 tcgcttatgg atgtatcaat ctgaattgaa atcagaatta gataggttgt tagtcagaag
    22801 tataacgatg gggaaaaatc ccaagcaact tgcatctaaa ttggcagaat atttaacagc
    22861 tgaaggacga gaaaacacta agttcaacac tcaacgtttg atggtgactg aaacgactag
    22921 agttcaggta gggattcaag aacgaagtta tagagatgca ggcattaccc agtacatcta
    22981 tatagcagaa ccaacggcgt gcaaactatg tataccgtta aataatcaag tttttgatgt
    23041 tgccgatatg cagccaggaa gtaacgctcc taatatgcat ccattttgtc gatgcagtac
    23101 agcaccttat atagaacgaa tatcaagccg ttaacacaaa ttaacggctt tttattgtgc
    23161 cttcttacag cttacaggcg ttaaagagaa agctattttc ggctgaccgg cgtaactggt
    23221 caaatttatc gggtagcggc gtaaccgtgg aggattaatc atgaaaaaac gtttatttat
    23281 gccaatgaac ttacaatttt tttctgaacc aggagatggt ggatctggtg atgagggaca
    23341 acaaggaaac ctaccagctg gctcacaaga gacaccgccc gaagcaaaag aagaaaacaa
    23401 tactggcaaa acattttctc gtgatgaagt agcgaaaatg atcgctgctg agacgaataa
    23461 agcaaaagca gcgtgggaaa aagaactagc agcaaaaaaa gaagaagcta aaaagctggc
    23521 aaaaatgaat gcggaagaaa aactacagca tgagttggag caaaaagaag ctgaaatcgc
    23581 tgaattaaag cgtggacagg cactatctga aatgacgaaa gaagcttcta aaatgctgac
    23641 agatgcaaat ttaccacacg atgatgattt acttggtctg attgtttctg atgatgcaga
    23701 tgccacaaaa caagctgtag cagtcatcac taactttgct tctttgatta agagagaaaa
    23761 cgcaagacaa acaccaccaa atgaaggtgg acaatttaca gcatcgaaaa atactaaaga
    23821 aacagtggct aaactagctg ctaaaaatcg aattatcaaa taggaggaaa acttaatgaa
    23881 aaagaaacaa cttttaccaa tgaacttgca aatgtttgct caaacatggg atccagataa
    23941 tgtcttggta tatgaaacga aagagggaaa aattcctgat aaatataata cgctcatttt
    24001 gagtgaagtt atggaaaatt ctaagatcat gcagttagca aaatacgaag aaatgactga
    24061 caaagaaaag aaatttgaat actttgcaga aggaccaggc gcatactggg tgggtgaagg
    24121 tgaaaaaatt aaaacgtcta aacctaaatg gatgcaagct acgatgactg caaaaaaact
    24181 cggtgtcatt cttccggttt ctcgtgaata tttaaattat aaattatcag atttctttga
    24241 ggagatgcag ccaaaaattg ctgaagcttt ctataaaaaa tttgatgcag ctgccttatt
    24301 aaataaagaa aacccatttc ctcagtcact agacggatca gttattagtg cggggaatgt
    24361 ggttgaaggc ggattgactt atgataatat cctagcctta gaagacaagt tagcagaaaa
    24421 tgaattcgaa cctaatgcgt ttatttcaaa ccgaaaaaat cgtacagaat tacgttctgc
    24481 agctcaaaca gtcgggtcaa atgttgagtt tatttatgat cgctctacta atacaattga
    24541 cggattacca gtagtagacc ttaagtcttt agataaagga acactttacg ctggagactt
    24601 taattacatg ttttatggga tcccatataa tatttcattt aagatttctg aagaagccca
    24661 attgtctact ttaactaatg aagatggaac cccagttaac ttgtttgagc aagaactgat
    24721 tgctttgcgt gcaacaatgg atgttggatt tatgattgta aaagatgaag catttgggaa
    24781 gatttcccca aaagcgtaac gcctgctacc ggtattgtgc caaatcaaaa gacatggacc
    24841 ggtaaagtag gcgatactaa aacatttact atttcagctg tgcctgcaga tgctagcgat
    24901 gcagctgctg ttgttgcagc tactacagca acttcaagtg atggagctat cgcaacagtg
    24961 accaaaaatg aaaatggtgg ttttgatgga acgattgcag cagaagggtc agcaacattc
    25021 acatttactt ctggagaatt cactacttca atcaatgtga caggtcaacc tgctagttag
    25081 gaagtaaaaa tatgatgatt gcagatgata ttaaaaaact tcttaaagga acaatagatg
    25141 aaaagcttga agttattgag cgaagaacga atgagcgtat gaaaaccttg ttaaatacgc
    25201 aagaagttcc taaagaattt gaaacagttg tatatgaagt atcgttgaaa agattcaata
    25261 gaattggtca agaaggtatg cagtcatatt ctcaagaagg tttatctatg gcttttcctg
    25321 actcggattt ttcagagtat caaaatgaga ttgatgaatt taagcgtaaa gatcaggaag
    25381 agttgtacaa gccaaagcga gggaggttta aatttgtatg agatttacag atgaaattat
    25441 atttgttaaa cgttcatctg actctaaata tgatccagat ctcggtgagt gggttgaagg
    25501 caaaccagaa agaacaagaa cagaggcaaa cgtgacagat attggcactg atagaagtgt
    25561 gactattttt ggtagtgtgg aagaaggggc gaaggtcatt aggacgcagc ctcttttttc
    25621 tatccctaca tttgactata tcgagattga aggaaagact tggcaacaaa aaacagctag
    25681 aaatccagca tatagaaata gtttaattgt gcaagaggtg gttcttgatg aaggcacaac
    25741 ttgaatataa aggaatcgat cagctgatgc gacatctgaa aaaagcagca acgcttaatg
    25801 acgttcaaaa agtcgtgaaa agtaatactg ctgaaatgac tgaacgaatg caaaaaggtg
    25861 cgccagtgga tacaggttac ttacgaagat caataaacat gaatctttta gaagctggtt
    25921 taactggtat tgtaggaccg acagcagatt atgcacctta tgtagaatat ggcactcgat
    25981 ttatgtcggc acagccttat gttagaccag cgtttaatta ccaaaaagtc aaatttatgg
    26041 ctgaaatgaa agccttggtg aaatgatgat taagacaaga gatcaatcaa tttttgatga
    26101 actttttaaa atatcccaaa acaaacttgg atataaaaca tacgattaca aaactttaga
    26161 ggatgttggt tatccttttg tggaatttga gaacactcag acaatccatg aagtaaataa
    26221 aactgacatt aaagggtctg tgattgtggt tttatccgtt tggggattac agaagaaacg
    26281 aaagcagttg tcagatatgg catctgctct ttttaatgaa gctagattga tagaagccac
    26341 agaaggctat tattgggctt taaattatca agcaagtgga attcaagtga tggacgacac
    26401 aacaacgaat acaccgctaa aacgggcggt tgtcacactt gaatttagaa ttagatagga
    26461 ggaagaacat ggaagcatta aaaggtattg atgtcatttt gctttatcgc ttattgaaaa
    26521 aagaaactca ggaagccgct tggaaaatgg catttcaaac agaacacgaa aatggtttat
    26581 caagagattc agactctaca gtgacaaaag atggaaacgt tcaaagttta agcccggttg
    26641 aatatgattt ttcggctact tcaatagttg ctaaaggaga ttctcatgta gatgaaatga
    26701 aacaagcttt attaaatggg gatatcattg aaatttggga aattaataaa gcagaacagg
    26761 gaacagatga taatgcaaat aagtacaaag ctacttatta ccaagcatat gtgtctgaat
    26821 ttactccatc ggctgctgca gaggataacg ttgaattaag tttatcattt gcagtaaatg
    26881 gtgttggtca agatggttat gcaaccttga cagaagatca agccgatgtt gttcaatatg
    26941 cattcaaaga taccgtgaaa gcaacttcga caggagcata agagggctta gatgctctct
    27001 tttttatttt aggaggatga aaaacattga aattaaaaat taaaggtaaa gaatattcgt
    27061 ttaaatttgg cactaaattt gtacgtgaat tagataaagt gatgcctttc gtcgatggaa
    27121 atatggaatt tggaatggga ctctccgcaa aagtcttacc agagctacgt tcttataacg
    27181 ttaacacgtt atcacgagtt ctggaaatag caaatagaac tgaagatgaa tctattacat
    27241 tagatgaatt ggatgattac atcgatgaag ttaaagacat tgaaaaattg tttgatgaag
    27301 tcctaaaaga attggcggag tcgaacgcgg gaaagttagc ggtccgaaac ctgaatcaga
    27361 aattgaaaga agcggaaaaa caacaagtgg aatagattct gcactggcat acgaacaaat
    27421 tcttatcaat tcttttcgat atttgggaat gaccaatatc tcagatatcg aaagaatgac
    27481 gttatatgaa tacaacattc gtatgactgc agcccagtta tcttggcttg acaaagaaaa
    27541 gttgattcac gaattagcgt gggcaaatca gcaagtccaa gcggagaaaa aagtaggcaa
    27601 aaagacagtt cctgtatatc gatcctttga agaattcttc aattatcaaa aaatcgaaga
    27661 ttcaatcatg ggagtttccg aactttcaaa acaagataaa aaattccaaa gcttactaac
    27721 taaagctaac tcttgaggaa aggaggagaa tcatggaaca attttctgtt gaagccttat
    27781 taaaagccac agatagtgga tttgtaaaga cttttaaaga tgcacaagat gctgttaaaa
    27841 cttttgaaaa gaattcaaat agtatgacaa ccgctgttgg taaagtgatg caaggtactg
    27901 gtgccgcaat gacaaagtat attaccactc ctcttatagg agtaggcgta gcagctgcta
    27961 aagttggtgg cgacttcgaa gcacaaatga gtcgtgtaaa agctatatca ggagcaaccg
    28021 gcgacacatt cgaacagatg aaacagcaag cgattgatct aggagcaaaa actgctttta
    28081 gcgcaaaaga atcagctgct ggaatggaaa acttagcttc tgctggattt agcgcacaag
    28141 aaatcatgaa agcaatgccg ggtcttttag acttagcagc tgtatctgga ggggatgtgg
    28201 ctctagcttc tgaaaatact gctactgctt tgagaggatt tggtttagaa gcaagtgaag
    28261 caggacatgt cgctgatgta tttgctcgtg ctgctgcgga taccaatgct gaagttggag
    28321 acatgggaga agcattgaag tatgttgctc ctgtagctaa ttcaatgggg atttctttgg
    28381 aagaaactgc agcagctatt ggtattatga gtgacgcagg cattaagggt tctcaagcag
    28441 gtacaacgtt gcgaggagca ttgtctaggt tagcaaggcc aacaaaggct atgcaagata
    28501 caatggataa tttaggtgtt tcgttttatg atgctgacgg taaaatgaaa cctttaaaaa
    28561 ctcaagtaga attacttaaa aaagcttttg aaggcctgac gcctgaacaa caacaaaatg
    28621 ctttagtaac actatatggg caagaatcat tatcagggat gatggctttg attgataaag
    28681 gacctgattc attgggcaaa ttaacaaaat ctctgaaaga ttctgatggt gcagctgacg
    28741 atatggctcg gaccatgcaa gataatatga attcttccat cgagcaaatg tttggagctt
    28801 ttgagtcagc agctattgta attcaaaaga ttctagcacc atccatcaaa aaagtagcag
    28861 atgccatatc cggcttagta gaaaaatttg taagtgctcc agaatcaact caaaaattag
    28921 tagtggccat aggagcaatt gtcgctgcta taggaccgtt aatttttatg attggttcag
    28981 taattatatg gatcaatagg gtgaaagtag cttttaaagc tttaagtgaa agttcaaaat
    29041 tgtttagtgg attaagtaaa gcaatgggtc ttcttacaaa tccggttttt ctggttatag
    29101 ctgcggtagc actactcgtt gtaggtttca tctatctttg gaatacgagt gaagatttta
    29161 gaaacttttg gattggctta tgggagggaa tcaagtctgc tgtaagctcg gcagtagaat
    29221 ggattcagaa tgcatggaaa tctacaggag aatggtttaa caatttatgg aagtccatta
    29281 aagaaggcgc agacaatgtt tggactacag ttcaagaagc ccctgggaaa gcggcagatt
    29341 ggattaaaaa caaatggact ggaacaaaag agttcttttc aaatttatgg tcaagtattg
    29401 caaactctgc ttcagagatt tggaatagtt taaaagaagg tgtcatatca gttattgatg
    29461 atttagtttc aagtgctggt gaaaaatggg aagggtttaa aaatactata tctactgcat
    29521 ggaaaacaat tacaagtaaa atcaaatctg gttttgattt tatactaaaa tatattggtc
    29581 catttgtaag tagcttttca gatgtgttct ctaatatagt gaaagcaata acaagtatat
    29641 ttgctgaggt taaaaacata atagtaaatg cttgggaaat cattaagtct ttaatagctg
    29701 cgccactact gtttattata gatttaatta ctggtgactt cgaacaaatg aaagaggatt
    29761 tagatctaat ctggaacaca cttgtccaat cagtggtaaa tatttggaca tctgtaaaaa
    29821 atatatttac ggaatatatc ggtgcaatag taaatagtgc cgttagttta tggactggat
    29881 tcatacaaag tatttctaat atttggaatg aagtagttta tcaagcgact atgatttgga
    29941 ttgatttgaa actatttttt actaatttat ggattgatat taaatacagt gcaattcaaa
    30001 tgtggataaa tctaaaattc tccataattc aaacttggat tgatacaaaa tatggtgcaa
    30061 ttgaactttg gaataatcta aaacaatggt ttttccaaac ggttaataat atcgtgcaaa
    30121 ctcttataaa aagttggaac agcttaaagc aaggaacgat agatttattc aacaatacag
    30181 ttcaaggtgc taaagacatt tggacttcat tcaaatcttg gattggtgat ttaattactg
    30241 gaaccaaaga taacatcatt cagggatggg aaaacctaaa acaaggtact atagatactt
    30301 tcaacaattt agtaaatggt gctcaagagg catgggataa tttagtaaat gctgttagtg
    30361 acacggttga tagagtaact ggctggtttg ataacttgaa aaatatcgat ttactagcag
    30421 ccggaaaagc tatcatggat agttttctag aagggttaca aaatgcatgg aaatctgtgc
    30481 aagattttgt tggaggtatt ggtgattgga ttcgtgaaca caaaggacct atccaatacg
    30541 atagaaagct attgattcca gctggtcagg ctattatgaa cggtctgaat aaaggtctga
    30601 caggaggatt caatgacgta cagaatactg ttggaagtat ggcagacttt atcgcggaac
    30661 ttttcaatgc aaattctgat gtagatatag ctgcaaattt gaaaaatgca aataaaaaca
    30721 ttggtgcaca agttgaacat aaaataaata tgggtggctc tactaaacca gctgtattta
    30781 aaatcaatct tggaagacaa tcgtttagat tgtttatgga cgatatttca caagctatgg
    30841 gcgaaggtgc agatattaat ctggaatttt aggagggaat attttggatc aacgagaaaa
    30901 taaaatgtac tcattcaaag atacaaccat taatctcact agttctaaac gattccttcc
    30961 gacgtctgcc atgatgtacg atggaatgta tttagaagat ttgattgatg gttatcaaac
    31021 acttacggtg gaaggtagag aaatgctttc tgtagaagtt gaacagcaag agatacaaat
    31081 tggttcaatc attacaaatc agaaaatacc ttcaagaaca ctaaaaataa catataagct
    31141 ggaagataga gatccagaaa aactacagtt taaattcaaa gaactgttga attatttata
    31201 ccggaatgaa gacgtggaaa ttaggtttca tgatgaatta gattattatt actacggtcg
    31261 ctatacatca actgatactg ttccaggaga ctccaactcg attatttcga gttttaatgt
    31321 attctgtgcg gatccactaa agtatacgaa agagtgtgtt agtgatggct atattggaaa
    31381 tccgatacag tttcctataa caccaagaaa aattgaagtt actttatcca tgaataattc
    31441 aatcaaaatt acaaacggag aacaaaatat cacgataact gacgcggcaa taaaaacagg
    31501 agacgtgttg gtttttgatt tttccgatga gcaggtaact gtaaacggag aagattgtac
    31561 ttctatgatt gatttagaaa gtgattttga gaacttttat cttaagcaag gtcagaagat
    31621 aactagcaat aatgggaagc ttaaaatatt ctataggggg gcgacaattt gagtgagaca
    31681 gtttatttct ttgatcactt gcaaaaactt attaaaagaa aaaatacaag aagtttgatt
    31741 gaagtctccc aagaaaaaga aattagttct gataagagtg atctaatgaa agatactctt
    31801 tacgttacga caaaatatga taaagaaata gaggatgcaa gatatatggc gattcgtgaa
    31861 aacgagtcgt ctttttcgtt gtatcgaatt actaaagtta gcgacccatt tgaaacatta
    31921 gagtttacag ggttaggatt tgcgacaaat gaattagatg cttacatcat caaagatatt
    31981 aggccgagtg ggcagccctt aaaaaatgtt cttgatcgat tgattgaatt tactgaagga
    32041 aattggcgcg ttggtcacgt agaagcaatg ttaccaacag taactgcaac tttttactat
    32101 gtctctgtaa aagaagcgtt gaaagaattg caaaccttag gtatggaatt tgtctttagg
    32161 tgttctttga attctgatgg aataaaggat aaatggatcg aagtatatga acaaattggc
    32221 gaagaatcga atacacgttt cgtatatggt agtaaagcat taacagttgt aagagagata
    32281 gatagaagct caatctcaac ttcaatgata ggtcgtgggc gaggcgaaga ggttggtgac
    32341 ggttacggta gaagaattga attcactgat gttgaatgga aaaagtcgaa tggtgatcct
    32401 ttagataagc ctaaaggcca aaatcggctt gaagatccgg aatcaactca aaagtatggg
    32461 ataccacaaa aagatggatc aatgagaaaa cgagaaaccg tagtagtgtt tgatgatata
    32521 gatgatccaa cagatttact taaaaatact tattcaacct taatcgattc tgctagaccg
    32581 ttagtacaat tcaaagctga agtcactgga ggagatgtga taggaaatac agtgactatt
    32641 cacagatacg ataaaggtta tcactataaa actcgtattt ataaaactac attcaatcgg
    32701 cttaccggtc aaacgaatat cgaactaggg gataatttaa cacaagatgt tagaaaacaa
    32761 acggcttcta ttgtcaataa tattaatagt ttagaatcta gcaaaatgac attttacgaa
    32821 tcgacagaga ttggaaaata tcaagatgac attatgcgag gtgcaggaga taatggcggt
    32881 tctatttatt gggtaaatgg aattgaagct ggtgttagtg atagtagaga aatctatgaa
    32941 actgtttata tggatggacc taacattcct agatcacgct tttttatggt ccaaaataac
    33001 tcagggatat ctttcaaaca atgtaaaaaa ggtgagtggc aaacaattca agatgtacac
    33061 aatggtgata gcacgaccgc ttggacgttg gatggaactt tcaatgctaa ttttattcgc
    33121 gcaggcattc tgtctggtat cctcgtgcaa ggggtagctt taaaaacatt tgacgataaa
    33181 gatttccaat tagtggcaga ggggggagaa ctttcttttg aaaaacaagt caagtctact
    33241 ggactagatg atgtacatgg agaacgcttg ggctcaattg tatctactta tggttctaaa
    33301 gggattaacg gctttgctgt ctggaaagag ccaaactata ttttttccat taatgctggg
    33361 gacggtggcg atcgagggaa tcctattttt caaattccag cagatgttac tgctgataag
    33421 cgcaaatata atctttatgg tgacggcaat ttttcagaag gaaatataac catagatgga
    33481 cggctagatg taaaagaact ctatgttaac ggtacaaaaa ttgacactaa tggaggaggc
    33541 aattccggag ggaacgataa cggttggaac ggacaatacc caccagaagt aactactgat
    33601 cgggataaac gatattggca aatttgggca acggcaatag gtgccggttt tacacaacaa
    33661 gctgctgcag ccttacttgg aaatgcacaa ggagaatcag atgctaatcc aaccgctgat
    33721 gagggcaatg gcgcaccagg gttcggttat ggtgtatggc aatggaccga ttcttctggc
    33781 gcaactagcg gacgtgtcta catgatcaat ttaatgacaa aggctggcat cagtgatgat
    33841 ccagacacaa tcacggcaca gtttaaattg ttgatgtggc atgcaccaaa tggtcaatgg
    33901 atcgcaacta gcgcttatcc ttacacatgg acacaattca tgaatctgac cgatatcaac
    33961 acagcagcac aagcattcgt ggctaacttt gaacgtccac gtgatccaca tccagaacgg
    34021 acggcatggt cacaagaatg gtatgacaag ttcaaagatt tggaaattcc tgtatcaaaa
    34081 ggatatatga agccgattgc ggatccaatc acagtgacga gcgaatttgg ctggcgcact
    34141 tctccaatca caggagcaca agaatttcat aacggtattg accttgtaaa tggaaatcct
    34201 aatacaccta tttttgcttc agcggatggc gaagtgattg ttgcaggtga tgcaaattac
    34261 tttgactggt atggaaattg gacagtgatt aaacacgctg atggaatgta tacaggatac
    34321 gcgcatcaaa gccgagtaga cgtctcaaaa ggtcagaagg taactgctgg tcagcaaatt
    34381 ggactgatgg ggacaacagg accatccact ggagaacatc ttcattttca atttatggat
    34441 gagttttatc catcttcttc aggtcatttc cacaatgcaa gagactacat cgatttctaa
    34501 aggagggata gtcatggcag aaacgcagca taaaatggtc ctatccacca ccgaaccaaa
    34561 caacggaata aatttggttc gaattcggca aggggatgtt ttaacgcaaa agttcgttgt
    34621 tgaagtggtg gaacatggca aactaaaaac attcgagggc ctagtgccgt tttttattaa
    34681 tacaacaaaa tttggcgaaa accaacctgt tgaacaaaaa gtacaagaat acagtccagc
    34741 gcaagcaagg cttgtttaca ccttaagtga gcctgactgg caatggggtg gtgaaaacac
    34801 cgcacatttc agtttccgat cacttaatgg tgatggaact tggagtgaac aatttagcac
    34861 acaggatttt acctatcgag tcatttctgg aatatctaga agccagttac gtgactctgg
    34921 ctatgtgtgg acatttgagg atttgctaag aaaattcaaa gattacatgg atcagggcaa
    34981 aaatgactgg gagcagtggt tagaagataa tcgtgaaata ctggaaaata tcgatccagg
    35041 tggtatgatc attaacattc tgaatgaagc taaaggcgac tacgaatcat tagctgatcg
    35101 tttaaaccaa aaataccaag tgccagtcgg cagctcacaa attagagaaa caacacgctt
    35161 ttttgattac gacacgatga aatacgttga cctagtgccg cgcaatttga atacggttgt
    35221 caacagtgtt aataacagca aatttaactt ttctttcatt acagacattc acgcagataa
    35281 tcacaacttg cgtatagatg gcgtcggtta caaagatgct tcttatttaa gacattggcg
    35341 cgcaatccct caatttcaaa aattagggaa caaaacagat gtgatgattt acggcggaga
    35401 caatatcgac ggcggacttg gttcactcgg cagcgatata ggcattattg atgaatggag
    35461 cgcgcgacat tccatgttag gcacgctcaa acgcttcact aacgcagcgg tagcaggaca
    35521 agaaaaaccg gttattatct gcaaagggaa tcacgacgct tgtttcgacc ccgcgtggcg
    35581 caagcgaaag ggaatgttat gcaacgctga cttcgaagag tattggaacg gtttgtacgg
    35641 tggcgtgttg ttcccagata aaaacgcagc aatttaccgt ttcgatactt gtgattttta
    35701 tgaaggcggc acaggcgaca agtacgtgga cggttacagc gatacagcgc cgggagcttt
    35761 cagtgccaaa caaattaacg ctttcggaga atggttagtg aacgttccga gaaactatca
    35821 tgtggcgtta gtaggacata cgcctttagg tctcagcaag tttcccgttc gcaatgaaaa
    35881 catgattagc acgttgatag aagggtttaa atctggtagt ccggtaacta tcgattggtc
    35941 taaattagga caaccgaatg acggttcgtt cggcggatta aagaccttcg caatgaatac
    36001 aaaaggcgcc ggcgttgtag taggttattt ctgcgggcat tggcacgaac aagtcgaagg
    36061 ggcgtttgga acagtaaaaa tgattctttg cgacgtcggc ttctctcata cagctagcca
    36121 agttgataca ccggatgaat tagcgtttta taaaatagaa gttgacacag caacaagaaa
    36181 agtgacaagc aaaggcgtag ggcgcgcgag agacttcact tataactatt aaggcggtga
    36241 acaattaaat gttagatttt caaagcaaac caaatatttt tgaagaaatg agttatgaag
    36301 aggctgtgaa atggttattg cgtcaagcgg ctatccatta cgacggctcg gatcacgacg
    36361 cgcacgtcct agctactgaa agcaacgcgg gctttgctac accggaaaca gttatgcaag
    36421 cgcgtgggcg ttggttacgc gattataagc taccacaaaa atatccgaac attttagaca
    36481 ttccgcccgg caaatacgca accaaagccg gatggggcgc agacaaccct gacgggattg
    36541 aagatgacag ttttgttgaa atgatggtat tcgcggatca cgattcgaga aaattaatcg
    36601 tcgcttttgc tcgttatagc ggcgaaattt acatcaaaat gacacataac agcgaaccgg
    36661 tagagggtta taactcgtta ggctggcggc gcgtttacac tacttctgtt ctttttgaag
    36721 gcgaattaag aaaaggacaa tcagtcaatc tgccagatga tactttccgt taccaaacgc
    36781 ttcgtatcca ctacacagac ggtgacggag actttgtaga agaagtgaaa cgtcaaagat
    36841 acgcgcgaat tacaaaagcg aatttatgga atggagacgc gggagtgacg ttcatcgaat
    36901 ttgagctgac aatcgaagcg cgaaagataa cgatgtcaaa cggcagagct ttagatattt
    36961 catccggcaa tgtttccaat cccgcaatga gcaacaacgt gaaaataact aagattgaag
    37021 gtgtgaaata atggcgcatg tcatcaaaaa aggctctatc aaagtaccta cacagccgaa
    37081 agactacgat ttgcaagcaa cggggcttgt atttaaatca tacgataatc aaatagcgtt
    37141 agagttcaac gtcgaacaac agaacggcac accggcggac ttgctaggag ctaacttgcg
    37201 cttgttgatg tttatctatg atgaagtaga tggaatgatc acgaaagagc caatcccttt
    37261 tatcacgaaa aacctcatca ctgaaagctt cttgaatgga caggtcgtat atatcttgcc
    37321 agaagcgatg aaagcttata acggtatggt ggaagcttat gtttacatcg agtatccaga
    37381 cggatcaaca agtgataact taggcttcac cttccgtatg aagcgttcag caatcgacgg
    37441 actagcgcaa gataaagcag actactttat tgcagacttt caacaattac ttgatggagt
    37501 caaacaagaa gcaacagatg ctgttaacgc agcattaaca aatgtggatt ctacgattga
    37561 aaaggcaaac caacaaataa atgaatttgt agagggagcc acacaagcaa ttgatcaaac
    37621 tgttgacgag gtaacagagc aactacaagc tactcaaact aagattgata ccgtttctca
    37681 aaacgttaca tcggcacaaa acaatcttaa agcagttgaa gacaagatga atcaaaccaa
    37741 tcagcaaatc ggcgacctcg gcaagctgaa aaagatgtac agtaacagca tcgacttcgg
    37801 gaattatgat tatagtggga atccgaattt aatgtccaaa ctaaaatcga gcgattttaa
    37861 cgttggttac cacgggtcac taacttcgga taacgaaaag ctacatttta cttctgatgg
    37921 tacaggaagc attattatgt ttacgcgtat taatacacct cagcttgcta gtgggaaaac
    37981 ctatactctg agtgcgaaag ttcgatttga tgaaggaact acaggagcta ttgataaatt
    38041 acgtttggtg tatcgtacat caccaggaga aaagatatta ttggaagcaa atagtacaaa
    38101 tattacaaca gatgatgtag ggaaagaaat aacaatcaaa ggtacagcta acgttaatta
    38161 tcaaatcaca aatttagatc gattttatat gagtattagc tttgttgaca gggataaaat
    38221 aaatggcgga tttaagttgt acgacatcaa aatcgaagaa ggctcaacag ccaccccata
    38281 tcagccaaac ttacttgatg acccttactg gctaggtaaa gcgcctttgg gtgagaatat
    38341 tgctaataag tctgttacgt ttccaatcaa atctagcgcc tacagcctat accaagctaa
    38401 catggaagaa gaatttgttt taggtcaaac ctatacaatt accatgaagg caaccaaacc
    38461 acctatccaa acgttcattg tttacaacga ggatagtgga gattatagat atggtaactt
    38521 agagccagta gaagggttag ttgatacatg gggtctgact tttacaccgc agaaggttgg
    38581 agttaactac cccaaacggt taactattat ccagtatccc caatcaacaa caggtgcatg
    38641 tcaaattgac tggctcaaga tcgaaaaagg cgacacacga accccgaata ttagtcagtt
    38701 taaatacttt ggtgaaggct tgaaagacag taacaatccc aatgattaca gttgggatgt
    38761 cacacctgaa tatactgaaa aaggcttgaa tgatgctgtt aatgtgtatg atcctcagag
    38821 agttgaaggt ttgaaaaact ttgccgatgg tattcaaata gcaggagata aagtgatcag
    38881 tgaaaatgat tgcactgttt atacattaac taaagacaac agtcaatcgt ttatcgatgg
    38941 gtatgcaaca tttattaaac acggaaaaga agttattgta aatggtacag taaagttcaa
    39001 aaaagcttat gcttttggtg taccacttga tgatgaagtc ccagatgaat ttgtcgcaaa
    39061 aattgttcat ggcatgctta caggtccgtc aggaacaagt agtgtatcaa aagcgatgta
    39121 cgtgcgaaaa gacttaggaa caattattac gaatagcgaa tttgctgcaa atgaatggtt
    39181 tacattccat ggtaattatt gggtagggga ggaataaaaa tgaaaaatat ttggaaatac
    39241 ggacgaacag gtggagagta tgctggacaa gtgcttgatg atatggttat gactgttcca
    39301 tttaccgatg ttccaccact cgaaggaatt cgtgctgatg gggaaccact aacgattgct
    39361 gatcagatgt ttgatcctaa actgaaccaa tggattgttt tagtgaatgt actagatcac
    39421 aacgatttaa acaatctcaa agcgatgtat gagtcgttag aaaatgagaa cggcgattta
    39481 aaacagctca acgccaaact catgctaagc gatgtagcga ttaaacagga aaatactgca
    39541 ttgaaagaaa aagcggatgg tttagcacaa atcaattcaa aaacgatgct tgcttcgttc
    39601 caaaatagca aagacattgc agaaattaaa gagcaactaa atccagcttc aaagggaggt
    39661 gagtagtatg tttagtttta gcgatgtgaa aatgatgtat gattggggct gttttactga
    39721 cgatcaagtt cgactattcg ttccactatg cattacagac gaagaagcag aaaaaatcat
    39781 taataaagat aagagcgcat cttaagtgat gcgtttttat ttaaggtaaa ggagttgtca
    39841 catgattaat ttaggagaat ggggaacaat cgcaggatca atcactgcga ttgtttcttt
    39901 gattttatta gtaataagac cagtcactgc atctttctcg aagattactg aaactctttc
    39961 aaaagtaagt cacaatttag atttgctgac taaagattta gaatcgagca aatcagatcg
    40021 attgatgatt catgaagaac taaagaaaca cgatgaaaga ttagatacac atacagaaaa
    40081 attggtagaa cacacacaac aaatcaaaac tttatttaga gaaagatctc ggtaaaaaag
    40141 aaaggagtta agaagaaatg attttacccg ataagtatta tcaagtcatt aaatggacag
    40201 ttttaacagt attgccagct gcatctgtat tagttgcaac actaggcaaa gcgtatggat
    40261 ggaatggaac agatatgaca gtactcacta tcaatgcagt agcaacattt ttaggcgtta
    40321 tcactggcgt gtcggcttat aatttgaaaa aataggagga aacaaatgaa aaagaaaatt
    40381 actattactg cgatgagcct attaacggct ctttttttat tgccaattaa tgggtttgcc
    40441 tatacgatta acaatgaatt taatttaggc ccaaacgaag gtagctcaca agtagcaaat
    40501 aatcagtaca ttttactgca tgaaacggct aatgaaacag caacaggacg caatgaagcg
    40561 cagtatatgc aacgttcatg gactagcgct tatactgctt atattgtggg agacggcgga
    40621 attgtttatc aagtcggtca acctggttat gtacagtacg gtgctggttc gtatgctaat
    40681 gcaaatagtc ctgtgcagat tgagttacaa cacacacatg ataaagcaac gtttgagaaa
    40741 aactacaagg catacgttga attagctaga gattcagcaa tgaaatatgg tattccactt
    40801 acactagaca caccgtataa tcaaccaggg atcaaatcgc atttatgggt aacacaaaat
    40861 atttggggcg atcatacaga tccttacggt tatctttctg aaatgggcgt aagtaaagaa
    40921 aaattagcct atgatttggc tcatggattt accgatgaaa atccgacaac ttcagatgat
    40981 aaaccagtca ttgatccaac tcgagcaggt gctgcaaatc ctaccctgac agatggaaca
    41041 aattacgccc acattgatca gttcggagaa atcgaaaacg caaacttaca tgtggctggt
    41101 tggcacatcg ctaactataa atacgagtat atcttcatta tggattacaa tactgggaaa
    41161 gaattagctc gagtaaaagc tgatggaata tatagaccag atgtaaatca agcttataat
    41221 actttaggaa atgttggcta tcatgtatct tttaacatgc gcaacttccc taataagaaa
    41281 gtctatgtaa tgatgcgggc aacgaatgat ccagaaggga acactaaagg cggagcacaa
    41341 gattttcatg ataaacgctg gtatttaaat attccgcaac gataaaaata gcccctcgtt
    41401 tttgagggga agtacataat gcaaatttgt ccataactta ttgattatct tgtaaaaatg
    41461 cggtaattta atagttagtg agaagaggtg cttaattata gttaaaaaag aggaaataga
    41521 agcagcatgt aaccaagcaa atgttaggtt tattggagaa gctttatctg gatatcctaa
    41581 gtataaatac ttacacaact ggttacaaag taaaagtttt tatcttaata aagaaagatg
    41641 catgcctaat aaaaattata gggtttataa aagaggaact attgtatatg ttgattttgg
    41701 ggtgaacgtg ggttatgagt tatctggtaa tcattttgct attgttttaa ataataaaga
    41761 taattcgaaa aatggtgttg tatgtgtagt accaatctct tcaaaaaaga aaagtaatta
    41821 tgtatctgta ggaaaaatat tagaagttgc tagtattaaa caatttataa gccaagctga
    41881 taaattaaaa gagaaactta ggataattat tttactttca ttaaatagag gcatcattga
    41941 tgaaagcgat ttgaatagtt ttattaaaga tattgaagct aaaggtgaaa agctttcagt
    42001 ggaagaagta gaaaaacgag ctgtaaaaca taatttggtt tgcgagacaa gggaacaagt
    42061 aattaaagaa ataaaatcat tatctgaaga tatggtaaaa tatcagaagg tgtttaattg
    42121 ctacaagaaa tatacacaag aatcctatgt aatgccactt aatatccaaa cgattagtaa
    42181 aaatagaatt agaagaatta acaagtttga tccttctgga aatatgaagg cacctggaaa
    42241 tgtcctcaat gaagtagatg aaagtttaaa aaaatatttt acaaagtaaa cgatattttt
    42301 gttgacattt ttctgttcgt tagttaccat gtagttatag aaggacgtaa gcgcctattt
    42361 ttaatgtaca catcgggacg tatgcgccca catagaaaca tagttgagag acatctatat
    42421 ggtgtctctt tttttattaa tatgcaaaaa agtctagttt tttcaataat atttatgtaa
    42481 taataaatta gccaccacaa caaagaatga aacccattat tatctagtct atgtccattc
    42541 tttttgtttg cagtagttgt gatggctttc cgtactctta gctcagttgg ttagagcaga
    42601 cggctcataa ccgtccggtc gtaggctcga gtcctacagg gtacatactc taagtgattt
    42661 aaattgcgaa taaaatataa aaatgactcc ccttttgact cccccaagca gtatatggat
    42721 gtctctaaaa gttgtttttt tagataataa aaagctgata ataagcgaaa aacacttaaa
    42781 atcagcttta aaccctattc tcgaaatccg gcgaaccggc taataccggc gcgcaggttc
    42841 aaatcctgta ccttccttat atcaacgatt agaggttgtg aagaagctgt cctgcatcaa
    42901 gtaataagaa cggccaaaca aaaatagctt ttcctatttt ttcgtttgat tgggcttatt
    42961 accgcagatg caagcttttg aacaccgttt gttcggaata aggggctgtg acaagacttt
    43021 tgtcacagcc ccttattgtt gtacttttaa cctacaatat tttttgattc cccctgagta
    43081 ctatttttta taaatgctag taaatcaatc ttctttggcc tttttttgat aaaaaaaata
    43141 ctagatgtaa gataaaagtg taaaaacgat ttgttttagg aggggaaacg atgtgtaccg
    43201 caatcactta tgcaacgaaa gaccattatt ttggaaggaa ttttgattat gagatgtctt
    43261 ataatgaagt ggtcactatt actccaagaa attatcgttt cgattttaga aaggtaaaaa
    43321 atttagataa acattatgca atgataggaa tagcagctgg ggtatccaac tatccactct
    43381 attatgaggc tacaaatgaa aaagggttga gtatggcagg actgaatttt cctggcaatg
    43441 ctgattataa agaattacaa gaaggaaaag ataacgttgc accatttgag tttattccat
    43501 ggatactagg gcaatgctca accatagacg aagctaaaga attattggct actatcaatc
    43561 tagtcaatat cgattttagt gaaaaactac ccttgtcacc tttacactgg ttattagctg
    43621 ataaagaaaa atcgatagta attgaaagta tgaaagatgg acttcattta tatgataatc
    43681 ctgtcggtgt gttgacaaat aatccgccat ttgattatca attatttaat ctgaacaatt
    43741 atcgctcgct atcaaatgga
//
LOCUS       DACCVZ010000018        41447 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.018, whole genome shotgun sequence.
ACCESSION   DACCVZ010000018 DACCVZ010000000
VERSION     DACCVZ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41447
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.018"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            214..498
                     /locus_tag="IVW63_000948"
     CDS             214..498
                     /locus_tag="IVW63_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HAP7859238.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(815..1198)
                     /locus_tag="IVW63_000949"
     CDS             complement(815..1198)
                     /locus_tag="IVW63_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HAP7859239.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(1200..1784)
                     /locus_tag="IVW63_000950"
     CDS             complement(1200..1784)
                     /locus_tag="IVW63_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAP7859240.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="IVW63_000951"
     CDS             complement(1831..3306)
                     /locus_tag="IVW63_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAP7859241.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="IVW63_000952"
     CDS             3487..3798
                     /locus_tag="IVW63_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859242.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="IVW63_000953"
     CDS             complement(3913..6249)
                     /locus_tag="IVW63_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7859243.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="IVW63_000954"
     CDS             6391..7059
                     /locus_tag="IVW63_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7859244.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="IVW63_000955"
     CDS             7062..8105
                     /locus_tag="IVW63_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7859245.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="IVW63_000956"
     CDS             complement(8342..9223)
                     /locus_tag="IVW63_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP7859246.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="IVW63_000957"
     CDS             9382..10110
                     /locus_tag="IVW63_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAP7859247.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="IVW63_000958"
     CDS             10266..10583
                     /locus_tag="IVW63_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP7859248.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="IVW63_000959"
     CDS             10576..11184
                     /locus_tag="IVW63_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAP7859249.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11200..12030
                     /locus_tag="IVW63_000960"
     CDS             11200..12030
                     /locus_tag="IVW63_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HAP7859250.1"
                     /translation="MRLKHFLITGIGLMLTGGLLAGATYTLGAQKSLTWDNGPRLIDM
                     VTETKKIKDANKIVIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKK
                     STGAIISLEDTSAQITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSF
                     NEFTGGTITAKDELGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSL
                     HEMENSGYTIQTSGESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD
                     "
     gene            12168..12656
                     /locus_tag="IVW63_000961"
     CDS             12168..12656
                     /locus_tag="IVW63_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAP7859251.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            12707..13579
                     /locus_tag="IVW63_000962"
     CDS             12707..13579
                     /locus_tag="IVW63_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAP7859252.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            13755..14117
                     /locus_tag="IVW63_000963"
     CDS             13755..14117
                     /locus_tag="IVW63_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP7859253.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            14126..14878
                     /locus_tag="IVW63_000964"
     CDS             14126..14878
                     /locus_tag="IVW63_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7859254.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            14892..16694
                     /locus_tag="IVW63_000965"
     CDS             14892..16694
                     /locus_tag="IVW63_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7859255.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            16971..18011
                     /locus_tag="IVW63_000966"
     CDS             16971..18011
                     /locus_tag="IVW63_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP7859256.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(18063..20207)
                     /locus_tag="IVW63_000967"
     CDS             complement(18063..20207)
                     /locus_tag="IVW63_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP7859257.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(20564..21937)
                     /locus_tag="IVW63_000968"
     CDS             complement(20564..21937)
                     /locus_tag="IVW63_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7859258.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="IVW63_000969"
     CDS             complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="IVW63_000969"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002829567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAP7859259.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="IVW63_000970"
     CDS             complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="IVW63_000970"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAP7859260.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(23385..24398)
                     /locus_tag="IVW63_000971"
     CDS             complement(23385..24398)
                     /locus_tag="IVW63_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7859261.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(24479..25078)
                     /locus_tag="IVW63_000972"
     CDS             complement(24479..25078)
                     /locus_tag="IVW63_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP7859262.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            25264..25965
                     /locus_tag="IVW63_000973"
     CDS             25264..25965
                     /locus_tag="IVW63_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7859263.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            25975..28686
                     /locus_tag="IVW63_000974"
     CDS             25975..28686
                     /locus_tag="IVW63_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAP7859264.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            29137..30765
                     /gene="treC"
                     /locus_tag="IVW63_000975"
     CDS             29137..30765
                     /gene="treC"
                     /locus_tag="IVW63_000975"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAP7859265.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(30825..32006)
                     /locus_tag="IVW63_000976"
     CDS             complement(30825..32006)
                     /locus_tag="IVW63_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP7859266.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            32258..33781
                     /locus_tag="IVW63_000977"
     CDS             32258..33781
                     /locus_tag="IVW63_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAP7859267.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(33850..34578)
                     /locus_tag="IVW63_000978"
     CDS             complement(33850..34578)
                     /locus_tag="IVW63_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7859268.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(34591..35871)
                     /locus_tag="IVW63_000979"
     CDS             complement(34591..35871)
                     /locus_tag="IVW63_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP7859269.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(36012..36614)
                     /locus_tag="IVW63_000980"
     CDS             complement(36012..36614)
                     /locus_tag="IVW63_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator AgrB"
                     /protein_id="HAP7859270.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            36859..37065
                     /locus_tag="IVW63_000981"
     CDS             36859..37065
                     /locus_tag="IVW63_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859271.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            37377..38096
                     /locus_tag="IVW63_000982"
     CDS             37377..38096
                     /locus_tag="IVW63_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP7859272.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(38177..38860)
                     /locus_tag="IVW63_000983"
     CDS             complement(38177..38860)
                     /locus_tag="IVW63_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAP7859273.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            39079..41265
                     /locus_tag="IVW63_000984"
     CDS             39079..41265
                     /locus_tag="IVW63_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP7859274.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT        13446 a         7346 c         8316 g        12339 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatggttt ttcaccatct ttataataaa ctggttattt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag cgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaactt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 tttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tttgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctgatttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aagcggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa aattaaaaaa
    12661 gtaacattag atatttattg aaggataaag gagcgcagga agtagcatga gagaaaaaag
    12721 agcattttat atcaatggtt atgcagggat tgtcggattg gtcgtattag ctttagttgg
    12781 attgtttttc ttctatttag gtatgtggca agcgaaagtt tgggcacttt ttttaagtat
    12841 ttttctttgg ttgatcacgt tattgttgtt aagttcggca actgtagtca gtcctaatca
    12901 agcaaaagta attttgtttt ttggacaata tttaggtacg attcgagaaa atggcttttt
    12961 ccttacgata cctttggcac aaaaaatgac tgtttcgttg aaagttcgga atttcaatag
    13021 ttctgtttta aaagtcaatg atttggatgg aaaccccatc gaaatctcag cagtagtagt
    13081 ctttaaagtc gttgatacag caaaggcatt attcgatgta gcgtattatc aagattttgt
    13141 agaaatccaa agtgagacag ccattcggca tatcgctagc caatacccgt atgatacatt
    13201 caatgagaat gatttgacgc ttcgaggaaa cacgacggca gtgtctgacg agttgcaaaa
    13261 agagctgcaa gagcgtttag cagtagcagg tgtcgaagta atcgaaacac gcttgaacca
    13321 tttagcctat gcaacagaaa tcgctagtgc catgctccaa cgtcaacaag caaaagccat
    13381 tttgtctgct cgacaaacca ttgttgaagg agctgtcaca atcactcaaa tggccttaga
    13441 gcaaatcgaa gatggacaag aaatcaattt caccgatgat cggaaagtcc aattgatcaa
    13501 taatttactt gtctcaatca ttacagacaa aggaacgcaa cctgttatca atacaggcga
    13561 catgaaagac cgtaagtgac atactttttg taagatagga agaaggagtt taggacggat
    13621 tattgtcttg aactcttttt ttagttgttt taaagaaaat gacaaaattg aaagaagaat
    13681 gatagttgat tcgaaggcag aattgttcgc ttttttctat aatcagtata taaagtaaga
    13741 gagaagggga aaaagtgaaa aaacttctga tcggtctact tgttttcatc gttgtggtac
    13801 ttgcaggggt gaaaatcgca gattacgtag ttatgggtgg agaagaatac tatgtacaaa
    13861 ttacgacaga tggtacaaaa acagtttcaa aatcagactc tggacaagaa acagtcaact
    13921 atagatatat cctgcctggc tatacgaaag agggtaagga aaaagaactg gacttcaagg
    13981 gacaattgac tcgaccgctt cgtaaaggag catatttaaa aatcacctgg aacaaaaata
    14041 aaggtgtcac ttcgtatgaa gaagtcgaaa aaaaagacgt gccgaaaaca gcactggaaa
    14101 aactaattaa agggtaggga aagaaatgaa caaaatagtc gaagtacaga atgtaacaaa
    14161 agtatacgga aaaaacaatg agaaaaagac gcaagcatta agcggcatca gcttcgatgt
    14221 agaaaaaggc gaatttattg ggatcatggg cgcttctggt tctggtaagt cgacactttt
    14281 gaatatttta tccacattag ataaaccaac agatgggcat atccgaatca atcaaaaaga
    14341 tgtgaccaca ttaaaaggaa atcaactagc agattttcgt gcgaatgaga ttggctttat
    14401 tttccaagat ttcaatttat tagaaagctt gacagcacaa gaaaatatcg ctgttcctct
    14461 ttctttacaa ggcgtcagac caaaagaaat caagcaacgt gtccaaaaaa ttgcagaacg
    14521 tttatccatc tctcatattt tggaaagcta tccttctgag atttccggtg gacaaaaaca
    14581 acgggtcgcc gccgcacgtg cattgatcac acaaccaacg attctattag gggatgagcc
    14641 tacaggtgcg ctggattcca aaagtgcccg ggatctttta gatacgatgg acgaattgaa
    14701 tacaaaagat catgtatcga ttcttcttgt gacgcatgat ccgttttctg caagttattg
    14761 ccaacgtatt ttattcatca aggatggcgg tatccatcaa gaagtgaaac gtggagatca
    14821 aagccgtgat tccttctatc gagaaatact atctattctt ggaaacttgg aacagtaggg
    14881 ggagattgac tatgctttgg aaattatcac ttactgggat caagagccgt ttaagagact
    14941 acttggtgtt attctcagga ttagttatgg catctgctat tttttacatg tttgaatcaa
    15001 tggcaagcaa cgaagctttt ttgaaaagta atacgatcgt tgcggctaca gttatcattt
    15061 tccgattcgg ttctgtttta ctagggatca tcacattcgt ttatatttta tatgcaaatt
    15121 cctttttgat gacgatgcgg caaaaagact atgcaatgtt tatgatgctg ggagcaaaag
    15181 gcagaaaaat cgcacagatg attttttctg aaacattctt agtagggatc gcagctactt
    15241 tagtgggttc agctgtcggt gtaggattga caagtatcgt ccaccgatta ttagtggatc
    15301 agttagatct caatatttcg cattttacac cttttagtat tcacgggttg ttgatcactg
    15361 ttttgttttt tgctgttttg tttttattag ctgctgttgt caatgctttt tcgattgtca
    15421 aaaaaccgat tttagcattg attcgtgcgg atcagacacc aacaagaatc aagcagcata
    15481 aattcttgtt tttccttgaa gtagtactgg gaattgcttt tctaggctgc ggttactata
    15541 tgatgaaaca cgtggggacc tatcaagtct ttggtatagg ggtagcctta gttacgatcg
    15601 tattaggaac ttatttcatt ttccattctg tgatcatttt ctttttatca ttactaaaga
    15661 aatcagaaca gatttcattg aaaaaattga acaatttcac attgtcacag ttaaactttc
    15721 gtattcgtga atatacacaa atgctctcaa tggtcgctat gctgtttgcc ttggcactgg
    15781 gcgctttgac ggtaggatta ggttttaaaa atgaaattgc agacttgaca gaaaacaatt
    15841 ctggatatga tctagtgatg aataatcctc gggcagaaga tcagcaaaaa atcaaagaac
    15901 tttcaccaac actttctgct tcttatactc aaaaagaaga tgcgggaacg atttactata
    15961 atgcaagtga atttgcggct caaccattga tcatgataaa acatgaagat ggaacaccgc
    16021 cgaagatcac gaaagaaaaa gttcctgcta aaaaaatgaa tgaactgact gtacaagagg
    16081 aacttcgaag ctatgaattg ccggaacagc aagaaaaaga aatcaaggta gtcagtcaat
    16141 cagaatttga tcaactgaac ttgccacaat ccactttaca gctagttcag gtaaaagact
    16201 tccaagcaaa cctgaaacca atcgaaacac ttgttgctca aaataaaatg aacaatccat
    16261 ctttgcaaaa agtagagtac agcaaccaga aatatgaaat gtatgaagtg tataatggtc
    16321 tattctctgg ttttgaattt atgggattct tcctaggttt agctttcttg accatgcttg
    16381 ctagctgttt gatgttcaag atcttgtcag gaagcaagag tgacattgct cgttatgaaa
    16441 tgcttgaaaa gataggaaca cgacgcgggt tgcttaaaca atcgatccgt agagaagtag
    16501 gcgtgttatt cttagcacca ggaatcttag gtgtagtcca tgtcttattc ggattacaaa
    16561 tgtttggtct attcatgcaa aatccataca aagatatttg ggttccgttt acgatattct
    16621 tcgtattgta tttcatctac tatgtactga cgacatggtt atatactgga atcgtattga
    16681 aaaagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa gcaaaaatag
    16741 ctcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    16801 ttgttcggaa aaagaggttg tgacaatatt tttgtcacaa cctttttttc acggtctttt
    16861 attagaatat agtaaatttt ttctcgttac tcacggaata agctgttaag aaaacggttt
    16921 ccatgtatac tggaatcagt gcaaatgaaa gaaaagaggg tgcaaggaac atggaaatca
    16981 atgaacaaaa ttttggcgaa aactatcact tgattacgat cacgaatcaa aatgggacat
    17041 ctttgtctgt cagtgatctt ggggcacggg ttgttcattt tcaaacaata atcgataatg
    17101 aaaaacgaga gttgatctta ggttttgatg aagcaaaaga atatctagaa aaagaccctt
    17161 atatcggtgc ttcaatcgga cgtatggctg gacggattac gaatggcaca ttcaaattag
    17221 atgatgaaac gttcgaagta aaaacagacc cggacactgg tcattgttta catggtggtg
    17281 cacctagctt tgaagccaag cagtggcatt atacagtcat caatggtgaa aacgaagcat
    17341 cggtcatttt ctatcagact agcccagata tggaaaacgg atttcctgga actttagatg
    17401 tagaagtacg gtatacgctg acgaacgatg atacatggcg agtgacggtc caagggatca
    17461 gtgaccgcaa aacagtattc aatcctacaa atcatgtcta tttcaattta accggtgatc
    17521 cagcacagtc aatcgacgaa catatacttt ggttgaatag ccgattattt gctacgctca
    17581 ataaagatac aacgcctaca ggagaagtag tttcagtaag tggcacagca tttgacttcc
    17641 aacgtcctaa aaaattaggt gaggtctttg ccagtgattt tcgccaatca atgatagtgg
    17701 gcggcatcga tcatccattt ttgttgaaaa aacaatctgg tttactaaat gctgcggaat
    17761 tgacaagccc agatgaaaaa gtatcgatcc aagtaaaaac agatgcttca ggaatcgtga
    17821 tttttacagc aaattttgga gaagatggac cggaaatgcg cgggaataaa ttagtaaatc
    17881 atggcggtat cacatttgag actcaagaac tgccaggagc ggagcgactt gaaagttttg
    17941 gagatgtcac tctggaacct aaccaagtac gcgagtttgt aacggaatac aaaataaata
    18001 taaagaaata gaataaatta aaaagggagt gtgacagtgt cacatcccct ttttaattta
    18061 ttctatttct ttaaaggcag atcaagccag aatgatttgt ctaaacttaa caaggttagt
    18121 acaggaacag ttgcagcttt aactgtacga gtagttgttt ctggtatctg tcttgccgta
    18181 aaattgttcc acaaatccca gattgaagcg acacggaaga tggaagaagc gttgttgacg
    18241 cgttttatcg ttgaaaattc taatcctgtg attggcacgc catctgttgt ccatttgatt
    18301 ggcacatcga atcgcttaga catattgagg atttcagcgt ttgcttcttc agttgttgct
    18361 gcttcttttt tcggttcatc atattttgtc aggtcgtacg cttcgatgat cgcgttcaat
    18421 ttttgtgaat attggcgatc tgtagcataa cgtccttcca aatatttggt tgcttctttg
    18481 tagtcttttg tttccgactt ccaagttggt ttgtagaaat caggattgcc agtcagtcca
    18541 tttttgatca agtcggcata gtcttccaaa ctttccttgt aagaaggata tttacggaat
    18601 tgtgcgcgga tttggtagct ttgtccggaa ctatcttgtt caagtgtatt gaaggtcacg
    18661 ctgcttcctt tatatgatcc tttgatacca aaaaggttat gatttggttc gcttgataat
    18721 aagctgtttc cagatccact ttcaaggata gcttgagcca tcatgactga tgcgtagatt
    18781 ccttcttttt gcccgatttc ctgtgcatca tctgcaatct ttttcaagaa ctgatcagtt
    18841 gtttggtttt gactgaaatg gaacgagcca tctaatccat ctaaaataga tgagccgcct
    18901 gtcagcgaac ctgaagcagc aggtaaacct gctaagttta ctcggacagc aaaatcaggc
    18961 gtgaaatctg aaatagaagt tactcgaact ttatctcctg gttgaggcgc atggataaat
    19021 tgtccgttcc caatatagat acctacatgg tgagtaacac cggaagaagg tccccagaag
    19081 acgaggtcgc caggttgggc ctgacttact ggaatctgcg tacctgcata ttgctgttcg
    19141 cctgtccagc caccgatata atgaccggtt gctttcatat atacgtaata agtcaaacca
    19201 gaacagtcaa aagtatttgg accttttgct ccccatacat atggttttcc aagatgcttg
    19261 aatgcttctc gaacgattgc ttgttggaca ttcgttgtat ttgtaggcaa tacagcatca
    19321 attggtgatt ttacaacaaa atcagaagaa gcagaagatg gattctctat accgctttga
    19381 tttgctgtat ttggacgaga tgaagcattg ttcgttccgc cattcgatga accattgttt
    19441 ggatggtttg gttctctctg agtatttcca ttgttattcg atccagatgg gtttgtttga
    19501 ttcgaagaat tcccgctgtt cgaattattg ttattattgt ttgaattatt tgaaccatta
    19561 ttattgttgt tattacccac atctggtttg tttggcgttt ccggatctgg tgtactaggg
    19621 acttcttcac taggatcagt tggtttctct gttgaagtat ccggtccagc tttaaattct
    19681 gcagtaatag ataaattgtt cgtacctact gtaaaggtct ttgcatcata atttacttct
    19741 ttggcaccat taacagcgac tgaagcaatt tgttcacctt cagctggcgt aatagtgtaa
    19801 gttaccttcg tttccgctaa taaaccttct accgttccac tttccgtaat atccaaaggt
    19861 tgctgttcag gggaatccgc tgtcgaagca gtcagttgga tcttaccaat caaagaagga
    19921 gcaattgtaa gggaatatgt ctcggctggc ttttcatttt ctgatggatc agccggatca
    19981 atttcagttg gctcggtcga tcctgttgtt gagttagttg ttccagttgg gtcttctgta
    20041 aaagaatccg ttgtttcact agtagctgag ctggatgtag tcgtatctgt tgtgactgtt
    20101 tgatcagcta tttgattatc tacggcaaat acggtattgg tcgacaaaac agacggagca
    20161 atcagccaag tagcagctag caaacgtatc gtttttttat ttttcataat aaactagtcc
    20221 ttttcctttc attgattttc tgtcttattc agcattcatt agacattttt tggaacagat
    20281 aatcgtgtcg aaaagctttt tcttttcata aatctgtctg tgtattctaa ataaaacaat
    20341 ttgtaaataa gcaacgagca ttcattcgtt tttctttgac gttcatttta ttgcatagac
    20401 cacctttgtt tggggataaa caagtgggga taaaaatggt tatgcatatg taaattatac
    20461 caaagtttgg aaagtatcac aaaaatttat aaaaataatg atcctaaaaa gaaaaagact
    20521 gaaatatgtg ataaacatct catacttcag tctttttcat taactattca taagacatta
    20581 ggtcttcatc aaacccgcta acgagagtag tgatcattgc tacgactaga ctaacagcca
    20641 gtcctgctaa gtaccagaaa aaagtaccgg aaatgaatgc aggcaatgtg gtcagactac
    20701 caaatacaaa agcgatcgct ttcacttggg caaatcccat tacagctcca ccagcagctg
    20761 caccaatgca agcagcaaca aatggttttt tcaatgggat cgcaattccg taaacagttg
    20821 gttcggtcac tcccgcaagt aaaatcgaag caaaagcaga accggagatc gaacgggttt
    20881 ttgaacgttt acttcgcaga aatacaccta aagctgcacc agccattcca aaattggctg
    20941 ctcctgtcaa cggaacgatt cggtcgaacc cataagcaga gatattactg atcatgacag
    21001 ggtttacagc ccattggata ccaaatatta ccaaaatatt ccaaccacca gcgatgattg
    21061 cgccactgat cggtccgtta atatccatca tccaagtaat tgcggcagct aaaccttcgc
    21121 caaggtaaac acccgcaggc ccgaatacca ttaacgtcaa aggaaccgtg ataactaatg
    21181 aaagtaaagg tacaaatact aattgcatat tttcgcgaat atattttttg aggaattttt
    21241 caacaaaaga ataaaagaaa atacctaaaa tcgccggcat gacagtagac gtatactgca
    21301 tcagtactac aggaatcccc agaaaatcag tagctgcttt gccactgtct gaaagtaaag
    21361 aggtcagatt cggttcaatc agtgctgcag caatgacagc cgcaatatat ccattcactt
    21421 taaacgtttt ggcagcagaa aaagcaagaa agattggcag aaaataaaag acggcattcg
    21481 acgcagcaga caaaatatga taagttccgc ttgtttcact aagccagcca atcgtagtcg
    21541 ctaaaacaac cagacctttt aatataccag aaccggcaaa cagcggaatg atcggcgtaa
    21601 agatttccga tatcaaacca aatagttttt cgatcggatt tagcttttct ttcggagctg
    21661 aatgatcgat ttgacgcgtc aattccttgt aagcaggagc caatccctga tccatgatta
    21721 tttctgcata tctatcgagt aaaatgaaat acttaatgga agggatttgc tgttttaatt
    21781 tttctgcatt ggctactggc tgttttttca atttgatacg aagccgagtc gcacatggaa
    21841 ggacagaatc aatattgtct tttcctccca actgttcaat cagcatatga atctgctcgg
    21901 acagtaccat ctgttcagga ttcattgtcg tttccattag aagaccactc cactcactaa
    21961 tataatattg gcgtaaggtg tcatttcgcc tgtacgaata aatgcatgac agttattcaa
    22021 ctcttttttc atttcttcat gtgggataaa gctaatcggt gtatctggta acaataattt
    22081 gattttttcc aatatttccg ggttcattgt ctttatttct tccgccaatt caatcgattg
    22141 tacctcaagt tcttctaaaa cgttttctaa aacagataaa aaacttggaa gaccgtttga
    22201 gacagccaaa tctatttttt cagtaccaaa ggggacaggc atgcctgcat ccccgatact
    22261 taatttatca aagtgcccca tttgtgcgat tactcgtgaa atatctgaat tgattacttt
    22321 tccttttttc atgtttgttt cttcctctca ttgttaattt tagactgctg attgttctaa
    22381 agcttcgcgg taagggatag aaggttgcgc accataagac tgcacagcaa cagaagaggc
    22441 tagatttcca taaaggatcg cttctttcaa gttactaagg tctggctgaa gtgtgctgct
    22501 taatgcgcca ataaatgtat cacctgcggc tgttgtgtca acggcatcca ctttaaaagc
    22561 agggacgata ccgtgttctt tttctgtatg atagaaagcg ccggcactgc ctagtgtaat
    22621 gattactgtt ccaataccta attcatggag tttttcggct gctgcgacca aactgttatg
    22681 atctgtcact ctgattcctg taatgatttc tgtttctgtt tcatttggta taatgatatc
    22741 tgtcttttca agtagttcag taggaatcgt ttcacgagct ggtgcaggat tcaggatcgt
    22801 tgtttttcct gcgtcttttg caatagaaaa agctaggatc gtcgcatcta agctactttc
    22861 aaactgagca ataataaagt cactgtttgt aatcagttgc ttgtttttta ggacttcttg
    22921 ttcatggaaa gcattatttg cccctgcatg gatcaagata ctattttctc ctgctgcgtc
    22981 taccataatc attgcttgtc cggttgtggc gccttggatt tcagctatcc cagatgtatc
    23041 gatgttttct tttgtcagta gatctaataa ctgttgtcct tcgctgtcag ccccaacgcc
    23101 tccaataaaa gatgtccgtg cgcctgaacg tttggctgcc actgcttggt tggcaccttt
    23161 acctccgcca gcgtgaaaaa tctcatgcgc atgcatcgtt tcgcctggct tgggcatgtt
    23221 ggttaaacga agggtagtgt ccatattaat acttccaatt actgtaaccg tgttcatttt
    23281 acaaacctcc aactatctca tttattttga tgggaaaatt attttttaaa acgttttagt
    23341 aaaacgtttt aatagttcga taaaaatata gcacaccttg aaagctattt caagggtgca
    23401 gttgaaaatc ttttttctaa tcgtacaggt aatctttttt cttcccattc tttttctggg
    23461 aattggatcc gatctaacaa taacttggca gatgtttgtc ccaattcgaa gattggttgt
    23521 gcgatcgttg tcagtttcgg cttgatatac tcgcacatat ctatattatc atagccaata
    23581 atgctgtagt cttcagggat gctttttcca gcttcctcta atccgcgata taatccaaaa
    23641 gctaattcat catttaaagc aaacacacca gttgcagcag aatcaagaag ttctgctgtg
    23701 atctggtagc caccttgttt tgagaactgt gtaggtaaga ggatcagttg gtcgtgaggg
    23761 atttggtaaa catcaagagc agatttaaac ccctcaatcc gagcgtggac attttccggt
    23821 ggattttcag gatagacaag ggcgatcgtt tgatgtccta gactaagcaa gtgcatgccc
    23881 gctaggtaac caccgcgaaa atcgtctgtt cgtacggcat cactaaatcc ttcagatttt
    23941 ttctgatcca aaacaatgaa gggccggcct tgttttttca aattttcgtt gattgcatct
    24001 gtagagacag cagaagtcgc gataatgaat ccatccacac ctcgacgtgt gagctcggct
    24061 agatattcga tttctttttg atgatcagaa tcagcattac ataatatcgt gacgaaattc
    24121 tgcttataca agatatcctc aattcctcgc atcagtgtac tgaagaatgg attcgtgata
    24181 tcaggaacga gtacaccaat tgttttcgtt tccttggtaa tcatttgtct agcaaaatag
    24241 tcaggctgat agcctaattc ttctttggca gctaaaactt tctgaacagt tttcggactg
    24301 aatttctccg tatttccatt taatatcaag gagacagttg tgattgaaac gccggaaagt
    24361 ttagcgactt ctttgattgt gatctttttt ttcaccatgt tcatactcct atctaaatcc
    24421 tgtggttatt ttcccatgaa atcaaaaaga agtaaatgaa aatcacgtgt gccagtactt
    24481 atttgctttg ttggatagct tcgattattt gtttcgttga gcgtactcgt gcagttttcg
    24541 gaaatatctt ttttatgaac aattgatggg attctttgtc acgatcactg caagcatctt
    24601 cagcaagcac gatatggtac ccgtgttgaa aggcatctaa tgcagtagca tatacaccgt
    24661 ttgttgtcgc tacaccgctt aaaatgatag tttcgattcc acgccggcga agttgaagat
    24721 caagagaagt accaaaaaaa gcacttggat tgtattttgt gatagtcaac atattatctg
    24781 tatctttcaa agaatccttc aaaagtaaat cagtgaattc tggaggtaca gaagcagtca
    24841 ttccacccat atcagtttgt tgactcaaat aagggaaagt ggagatgtct acgttcacta
    24901 aaactttcaa ggcagcggta cgtttcaatg ttcttactaa caaatcattg tttgtcagaa
    24961 tagatgctgc agtgtgtgga gagagtgtac cgttatttac gatctctttt tgcatgtcga
    25021 tcgcgacaaa agcagttttt gataaatcaa aaatcatatt ttcctttaaa tcattcatga
    25081 tgttccttct ttcaaataac aatgtttttt atgtaagtaa atcataaatc gtttatttgt
    25141 caactaaatt aaaggattcc tttctttagt ctagagaaat tcagtggtaa aataaataag
    25201 tgtgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa tggaggaatc
    25261 agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg agaaacgacc
    25321 attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt gattatactt
    25381 ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat ggatacacct
    25441 gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga taaacagctt
    25501 actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct cgttcctaat
    25561 ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc gcttgatcct
    25621 gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc gtcccaatta
    25681 tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa tcccaaactt
    25741 cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca agtattgaaa
    25801 ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac acataattct
    25861 gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt aaggtctgtt
    25921 gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga ttttatgaaa
    25981 acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg acgattcatt
    26041 gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa aactgctgga
    26101 cctgtcatgc aaaaaacgat ggatcactat gttggtacag caggactttc tgatttgcaa
    26161 atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa gatcccagat
    26221 gcaaaagtag aaacaggaaa acagatctat tattccaata ctggcaaaaa cgaagtgatt
    26281 caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac tgatggaaaa
    26341 ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga agggtataaa
    26401 atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta taccatcacg
    26461 ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc gaacgtcgga
    26521 aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac agatatttat
    26581 tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag caaagcttac
    26641 aaagataaaa tggagcaaaa tcaagaaaag gcagaaaagt atttacaaga tcgacccgaa
    26701 gaacgcttag aagagctgaa aaaatcggcc aacgaagaat tagaaccggc acagcaaaaa
    26761 atagcggatg gcaaagcaca aacaacgcaa gcaagaacac ggttagaaga tgctaaaaaa
    26821 cagttagcgc aacagtcagc aactatccag cagcttcctg aagcgcaacg aacaatcgct
    26881 gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca attagttgag
    26941 aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga aaaaattgaa
    27001 aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg ttttcaagaa
    27061 tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt tttctttttc
    27121 tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga aaaccgcagg
    27181 gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa aaaatatgca
    27241 atctatgcaa gtctagcctc agggataggt attgttttag gaacgatatt aggaacgaat
    27301 cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg gagtgcgctt
    27361 attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat tgccgcattt
    27421 ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc attgcttcaa
    27481 ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc gctgtggtca
    27541 cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa gtcaagaatg
    27601 cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg cgtgggattg
    27661 aaagattctc taagttctgt ttcagccaaa caatttggac cgatcattga ctatcaagca
    27721 atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga tatgctgcag
    27781 aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga attgagaaaa
    27841 aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc tgatttggat
    27901 cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa aacaggaatc
    27961 gctattacgc aaaaagtagc agaactattt gacttatcta caggagatca tatttcgctt
    28021 tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa aaactatcta
    28081 ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca atcgatgatg
    28141 gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga aatgctttcc
    28201 gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa acaaatcgaa
    28261 acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt cgtattatca
    28321 ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc cgagcgtgta
    28381 cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac gatgtacatt
    28441 gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg tgtaggatat
    28501 atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt tccattagtg
    28561 atcacatggt gggcttatgt cttatcagca ggattaacta tcgtatttac ggttattgtg
    28621 atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt gaaatcgaat
    28681 gaataaaaac agaggttgtg aaatcagcgg tttgacctga gtattagaga aacaaacggc
    28741 aaaatagttt ttcatatttt gccgtttttt gagctaatac cgaaggacag ctgattgaac
    28801 accatgaatc agaggttgta aaaaagccgt cctgcatcga gcaaaaagaa tactcaaata
    28861 aaattagctc ctcatgtttt acatttgaga agactgattg ccgtagataa aagcttttga
    28921 acaccattta tagaagaaac aagaatattt tgctatttta aacaagagga tagacaaata
    28981 catgtctgat ctcttgtttt ttattgggca acagacctct tagaatgtat aaagataaat
    29041 tttacaaacg ctttcggttc agttataata ataaatgata acttgtatat ataagttgtg
    29101 gtaggtaata aatcagttga atggaggtaa atatccatga catttaaaga caaagtcatt
    29161 taccaaatct atcccaaatc ttacaaagac agtaatggtg atggaattgg agatttaaaa
    29221 ggaatcaaag aaaaactccc gtatctgaat gatctaggca tcgacatgat ttggctaaac
    29281 cctatttatc caagccctca aaaagacaac ggttatgata tctctgatta cacagccatc
    29341 gatcctatct ttggtacgat ggaggaattc gaacagctaa tagccgaagc aaagaaatac
    29401 cggatagaaa tcatgctcga tatggtgctg aatcacgttt cgacagaaca tgaatggttc
    29461 aaaaaagcac tagcagggga ccagcattat caggacttct tcattttaag agaagagcca
    29521 acggattggg tatcaaaatt tggtggaagt gcttggtcgc catttggaga tacggggaaa
    29581 tattatttgc acttatatga tcggacacaa gctgacttga actggcggaa ccaagcagta
    29641 agagaggaac tattcaaagt tgttcgtttt tggatggaaa aaggggtaaa aggattccgt
    29701 ttcgatgtta tcaatgttat cggtaaagac gaacaattga aaaataataa agaaaatgat
    29761 ggcaaacctg aatatacgga caaaccaatc acccatacgt atctaaaaga attgaaccaa
    29821 gcaacgtttg ggacggattc cactatcatc acagtcggtg aaatgagctc tacgacgatc
    29881 gaaaattgta tcttgtatac agaacctagt agagaagaat tatcaatggt ctttaatttc
    29941 catcatttga aagtcgatta tgaaaatggg aataaatggt ctactcctcc atttgatttt
    30001 gcagaattaa agcgactatt tcatacatgg ggagaaaaga tgagtgaggg taacggctgg
    30061 aatgctctat tttttaataa tcatgatcag ccacgtgcgc tcaatcgatt tgtagctatc
    30121 gatcagtatc gaaaacaagg agcagagatg ctagcaacca tgatccattt gaaccgtggg
    30181 acgccctata tttatatggg agaagaaatc ggcatgatcg acccagacta ttcatcgatt
    30241 tccgactata ttgacgtaga aagtttgaat gcttataagt tactccttga acaaggattc
    30301 acagaaaaag aagcgtttcg tcggatcaaa gcaaaatctc gcgataactc tcgaacaccc
    30361 atgcaatggt cagacacaga acaagcagga tttactacag ggaaaccttg gttaaaagtt
    30421 ggaggcaagc tagaagagat taatgtagaa aaagaactat cttctgaaga ttctattttg
    30481 tcctattaca agaaattgat tcggctgaga aaaacatatc caatcgttgc acaaggagat
    30541 tatcatgctt atgaagcaaa tcatccggaa gtttatggct ttcttcgcca atttgaagga
    30601 cagcagctgc ttgtattaac aaatttctat gataaagata caaggatcgc catcccagaa
    30661 ggattcacag aagccaatat tcttatcgat aattattccg atactgttct tcatcaaagt
    30721 ctggagctaa aaccatacca ggcaattgct ttgctgaaaa attaaaacaa aaacacaaaa
    30781 cgtcgttcct acgagctatt ctcgtaagat cgacgttttg tgttttattt aaaataatct
    30841 tcttcagaaa atgaagagtt ttcatactct cctttatcgc cataaaattt attgtagcgt
    30901 tgtttgaatt tacggaaaat aaaagtaacg agtaatttga ctaacgtata gataggaata
    30961 ccaaaaataa cgcccacaat tcccattaga tcacccatga caagtaaaac gattaagatc
    31021 gtaatcggat ggatctgtaa acgatcaccc attactcgag gaatcaccaa gtcaccgtgg
    31081 agaagttgta cggcaaacca gacaatgaca aatttgacag ccataaaagt agagtcttgg
    31141 aatgcaatga tcaaacctgg aaagaaggcg ataaacggcc caatatatgg aatgatacat
    31201 aacaacccag cagaaatagc taaaacacta gcaaattcta atccgatcag taagaaacaa
    31261 acccagtaga ctgctccaag gataaatgaa gcaatgattt gcccctttag aaatgaaccc
    31321 aattgttgat tagcaatctt tgtcaaattt ttaaaatctg tacgaaatgc tggtgggaca
    31381 atcgctaaaa ctgactgata aaatttttga ggatctctca aaaggaaaaa agcgacaatt
    31441 ggaccagtaa ataaagtaat aaaaatagct gtaacagttg aaaaaatgtt gctgatccgt
    31501 tgtgcgccac tttcccaata atttccaata aatccagcta tatcagacgt cacgtcgtca
    31561 atagaagcga aaaattgatt aaatgaatcg gcaaaaggtg ttttctccaa aaattgtcgg
    31621 agactctctt gaaaatcttg aaacaaatct ggcaaactac tgatcaatgt ctttgcctgt
    31681 tcttcaagaa aaggaataag ccatatgctt ccaagcccca ataaaaataa aataatcaca
    31741 taaacgataa tgactgacaa gttcctcgaa aggtgcttgc tcaaacgttt gatgactggt
    31801 tccaaaagat aatacaagat cagtgcaaac aataatgggg gcaagatagt agcgataatg
    31861 attccgacag gcttgaatat aaacgagatc tgatggaaaa aataaatgat cagcgcaagt
    31921 aagataacta ttcctaaaac atagtaagag gtttttcctc ctaaaaagcg gatcaaacga
    31981 ttcgttgtat ctgtttcttt tttcactctt tttcctcctt tatctataac ttcattatag
    32041 acaaaagcgg gtataaaagg aaaatgatag aggttgattg caaaaatatc gtcaatcatt
    32101 catataaact ttctcatcaa ttaaaataag aaaacgcttg acagttcttt taaccatatg
    32161 ataaattaaa tcctgttgct aaaacgtaac tattacggtt tgcgaaaagc gaatcggaac
    32221 attcaaatga aagaagatga gaagaggagt gtcataaatg aaacgattga taggtatatt
    32281 ggccatgctg gttttagcag gtatgttaac tgcttgcggg gcaagtggga aagccgagga
    32341 cagtaaagaa aaattgagcg tgatgacgac cttttatccc atgtatgatt ttacaaaagc
    32401 aatcgtcggg gatgaaggag aagtagagtt attgattcca gcagggactg attcccacga
    32461 ttatgaacct tctgctaaag acatggcaaa gatccaagat acagatatct ttgtttataa
    32521 tgatgaaaac atggaaacat gggtccccgc aatccaaaaa acattacaag aaggcaatgt
    32581 ccatacgata aaagcgacag aaggtatgct tttacttccg ggaagtgaag aaggacatga
    32641 tcatgaccat gaacacgggg aagaaggcca tacacatgag ctagacccac atgtatggct
    32701 agctccaagt ttagcaatca agcaggtagc aaacatacgt gatcagctga ttgaagctta
    32761 cccagaaaaa caggaagtat ggacaaaaaa tgcagcagcc tataccgaga aacttcaagc
    32821 actccatcag ctttatcaag aaacctttaa gcaagcaaaa caaagatctt ttgtcacgca
    32881 acatgctgca ttcaactatc tagcgttaga atatggattg aatcaagtat cgattgctgg
    32941 tctttcttct agtgaagaac cgtctgcggc gagaattgct gaactgaaac actttgttaa
    33001 agaacatgga atcaactata tttattttga agaaaacgcc aaagatagta ttgccagaac
    33061 gttagcaaac gaagcaggtg tatctttaga agtattgaat cctttggaag gattgacgaa
    33121 tgaacaaata gaaaatggag aaaactatct ttctatcatg gaagcaaacc tcgaagcgtt
    33181 gaaaaaaacg acagagacag aaaacccgct agaagatact ttgaccccca aaaaagaaaa
    33241 gagcgtctac aacggttatt ttgaagacga ggatgtacaa gatcgctctc tttcagattg
    33301 ggcaggaact tggcaaacag tagatacgta tgtagaagat gggacttttg atcctgtttt
    33361 tgaatataaa gaaaaattga atcaggataa gacagcacaa gaatataaag aatattatac
    33421 gaagggctat caaacagata ttgcttcaat caagatcagt gagaaagaga tggcatttac
    33481 gtttaagaat ggaacaacga aacgttcaaa ttatcgttat gtagggaaag aaatcttgac
    33541 ctacgaggca ggaaaccgtg gcgtaaggta tctattcgaa gcagaagata aggaaagtgg
    33601 cgcttttaga tatattcaat tcagtgatca cacgattgca ccggctgact ccgaacattt
    33661 tcatttatat gcaggaaatg aaagtcaaga agtattgctg aaagaaatgg agaattggcc
    33721 aacattttat ccagatacaa tggatggacg tgaaattgca caggaaatgc ttttgcactg
    33781 ataggcaaaa aagaaccgaa gggtttggat cggctggtca tttagtcggt ccaaactatt
    33841 cggttctttt tatgaaatca atttctttaa tccacggata gaggctggga tggtctcgcc
    33901 gtttgccaac gtgacttctc tggttttttt attaatcgac cgcacatttt gtgtattgat
    33961 aacataggat ttatgacaac ggataaaatt ccgatgcatt ttctcgattt ctttgatctt
    34021 ctcatagaat tgtaattggg catgagtcaa atggacttcc agtttatgtg gcgctcctag
    34081 cgaagtagaa aaatattgga tgtctttgat cggtaaaaat ttgatctcat cattaaactc
    34141 tattttgaag atatcttttt ggatttggga catttgaaaa tcttcgaaaa ttttgctcag
    34201 gatatgctcg acattttctt ttaaatcata aagatcttct ttgacgatat aatcagtcgg
    34261 ttcgatgttg ctttttaaga ttttcatcga catttccgta tgggaagtca catagattat
    34321 ttttcctaaa ggatctaatt cacggatcaa tttaccgatc gctacaccat ccatttcact
    34381 gtcttctagt tcgatatcta aaaagtaaat accaaaagaa gaagttctga tcttggctgc
    34441 attgagaagt tcttccggat cagaggtaga aatatggaca taactgtcta agttttcaat
    34501 catgattcta tttttgatca ccgttgataa aacttctaat tgttttggat cgtcttcaca
    34561 aatataaatg ggaatcatat cattactcct ttattttatt tgtatataaa tcgtttgaga
    34621 aaaacgctgg ttttcaattg atgtttcaag gaaaagataa ggattggtct ttgtcaattc
    34681 atccaagata aacaagccaa ggccttcgtt ttttggattt gtttttgttg agaacccttt
    34741 ttgtttcaac tggtttaacg gtaatgtatt tgttgttgta ttgatcacac gaatcatcac
    34801 ggaatgattc ttcttgagta tggtcaattc gatttttttc ttctttgcag cactagctcc
    34861 ttcaatcgca ttgtccaaga taataccaag catacgtaca aggtttaccg tatgtttcgt
    34921 atccagttcg attggctcag gaaaatgaag ctggacgatc aacccttttt cctgtgccat
    34981 catgagtttt aatgacagta aactacggat ctcaggaact ttcatattat ccaacatact
    35041 tagattggcc ggaaaaaggt tcatcatctg gcgtgtaggt aatatcgttt gatcataata
    35101 agaccgtaat ccttctaagt cgccttctga aatatagctg tgaagagaaa aaagcagatt
    35161 ttggtaatca tgtttgaatt ctctcaagtc ttgatagttt ttttctagat ctttgatata
    35221 atcctgttgc atcctgactt gttgctctaa taactgatca gctaatttct tattagagat
    35281 tttccaataa taaaccaaga tgatcaggcc aacacacaga tatagaatga aaaaactcgt
    35341 attcaaagct aagacatcag gtgtttcacc agaaaaacgg gtataaaaaa taatgatata
    35401 gtatgtaaat aatatcaatg tcccgatcgt accgatcata cggcggtcca cagtgtgaaa
    35461 ccaagtctct aacgattttt ttaaacaaaa agctaataaa gcagataaaa aagcggataa
    35521 gacaatgtga aaatactgca atgaatctcc tggttcaata accgaagatt tcaaaacaaa
    35581 aaaatcgccg atgcttgtta agtgatctcc taaaagcgac gtcaataacc caaaaggaag
    35641 cgcgtaaacc aattgttgac gcgaagtcga aaagaagaaa aaagtaagca tcagcattcc
    35701 tatagcaatt agagcagtaa aaatccctaa aatcgaatag acccatccaa tcaaaataca
    35761 agaaatcaga atgactcccg caaacagata tttgtatcgg atgtgatggt caatcaataa
    35821 gatacaaatt gtgtaaatca aatattgcaa cgctatggac cataaaaaca taaagtacag
    35881 ctcccattga tttttaccaa attatagcac aattggcgta ttattttttt aatttttcag
    35941 ggattttgaa ttcagaactc ataccaaagc agcagccaga tacaaaaaag tcagataagt
    36001 tagttaattg tttaatgatt gtttttttca tgaaagattc ctccaaaatt catcaagtag
    36061 tttgtaatag gaagcaacgt agctatttct aaaacaatcc caagtagcaa ataggtagaa
    36121 aagtaagaag ctgagaaaaa taacgtaatg agagaaaaaa ttagaaacat gctgatcgcc
    36181 ttctttaata atgggggacg tttctcgggt tcaatgggat tgattgctgt acctcttgat
    36241 ccatagcgaa gcagtaacaa aaagcagctg attaacaaaa agaccatcat tgggaaggag
    36301 atagtcaatt gcagatgttt catcaccaag ggaacgcccc ataaataaag tagtgtccac
    36361 agcagacaaa cgaattcaga gtcggaatgc aatccataag catatctgcg gatgcagata
    36421 taagaaagaa aggtgattcc tgtttccgcc catgagcctg tcaccagaga aaagactaga
    36481 acgaccgcta gttttccaag attattcaat aaaacttcta agacaaattt tacttggaca
    36541 tacaccatat cttcttccga tttgtctccg ctgaataagg cttctaataa tttgttcaca
    36601 actttatctt tcatctcata cgtacctcca ccacaaattt tatgctaaaa aaaataaaaa
    36661 acgtcttttg tttcataaaa agtggttttg acatcaaaac cgtcatgatc tcctaaaaaa
    36721 atcttcgttt tccaagaacc ttaccaaaaa aagtgacagt tttgatacga aaagtacttt
    36781 ttatgacaag tttgtgcttt ttcgagtgat ttatgttaaa aaattactga ccttataaaa
    36841 ggtgatggag ggattcttat ggaaaatgaa caattgtttg aagtcggcga aacatatgca
    36901 tttaaatctg atttatttga atcaccaata aaaggaaaaa tagaaaaaat ctatgaaaat
    36961 agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca atgataccgc tcataatctg
    37021 cactggcagt tagttgtacg caaatcaagt acaatagaag aataaaaaca gataaaatgt
    37081 tgagagcata aagaggttgt gagtctcccg tttagctctg agttacaagg aataatgtta
    37141 aaaaacagct tttcatgttt tatgaatatt gccttgtgac cgaggtgttg gcaggagaat
    37201 actgtttatt tgaaaaaagg gctgcgacaa gacttttgtc acagccttta ttttcatgaa
    37261 taggagttac ttttggctac ttttagagaa gtagctttta aggagcagat aaagtcaagg
    37321 cttttatttc tataaatgaa gtagtaaaat gaagaacaga ttttattaca ggaaggatgc
    37381 cgataattgt gatcattgtt gcaggaacga tcggtgcagg gaaaagcaca ctaactgaaa
    37441 tgcttgccca agatttagaa acaaaacctt tttatgagaa cgtggaagat aatgaagtat
    37501 tgccgctatt ttattctaat ccagaaaagt atactttttt attacagatt ttctttttga
    37561 acaaacgctt tttggcaatc aaagatgctt tcagccatga tgacaacgta ctagaccgct
    37621 ccatctacga agatagtatg ctgtttcatt tgaatgcaga tttagggcgt gtttctgaag
    37681 tagaagtaaa gcagtatgaa ggtcttttag aaacgatgct gaaggagtta gaagaaattt
    37741 cgccacaaaa gaaaccagat ctactggttt atattcgtgt atcctttgaa actatgttag
    37801 cgagaatcaa aaaaagaggc cgggaatatg aacagctaga acaagatcct gaactctatt
    37861 cctactataa agaactcaat cgacgatacg aagagtggta tgaacagttt gatatatgtc
    37921 ccaaaatagt gatcgatggg gacaaatatg atttcgtagc cgatccggca tgtggagaac
    37981 aaatcgtaca agaaatcaag atgcgggcaa agaaaatgac agaagaggca gatgcccagt
    38041 cgatccgcta cactacaaat aacccgaaag caaagggaat ctttacaact aaataatata
    38101 aaaactaagc aaattgctca ctcgcagata tttctctgtg agcagcatct tgcttagttt
    38161 ttttgattca ttgagatcaa atagtgaacc gattcgtatg ataaaattgc cataaatgaa
    38221 atgtctgagt gagggccatg atcaaaaata aaatggaaac gatcaaaatc gaatgggcgc
    38281 caaacagatg atgacagaaa acaaggacaa tagctcctgc gataaaggca agaacgacac
    38341 ttagatagtg gaaaaatcga tcaaaatctg ctttttcttt agaaatacaa taatcatata
    38401 agttcgttgc tacccctttt aaatttccag ttgtaaataa attagtgtag gcacgcccgt
    38461 tgattttatc aaaagctacc cactggatcg atgcagtaaa agcaatcaaa atcgttacta
    38521 atgcgggatg ctcatggacg ggtgtcaaac taacaaagaa aaaaatcact gcttcataat
    38581 atagaacaaa caagcgccag aaatgttttt ctttttttct aaaataatca attagatact
    38641 ttgttagaag aatccctaag aaaaagaaaa gggtagacaa tactttttta ccaacactta
    38701 gccattctcc gtcaaatgct tggatgatcg atagaatgat attgccagtt tgagcagagg
    38761 caaaagcacc atattggata taagtataac tgtccatggc tcctccgata aatgtcagca
    38821 aaagtcctat tgtacgcccc tcgtgaaagg aagtctgcat ttttttcatc accttttatg
    38881 aatatttttg tcttccttat cttagcataa acgattgaaa aaaaaggaaa aattttcaga
    38941 aaactaaaat catatcgctt cccattttca tttttagaaa ggtctgttag tataaagaaa
    39001 aaatagacaa cgaaacttta aataaccaac ttgaaataaa caaattcaaa gaagaaagat
    39061 gggaaggaaa tcaatcagtt gaatgaaaaa gaaattctcc gattacaaaa agaattgaaa
    39121 cgctgggaga acaagtataa aaagcttcaa caagtctttc ggctacaaga agaaatcatt
    39181 gctacctatg aagcggctta tggcgaagca cccggactta ttgaggaaga agtacaagta
    39241 aaagaaagtg aaggaaacag ctctttcttt aaaatgatgg agaaacgttc ctataatcgc
    39301 ttcaatcaag aacaaaaagc agctatcaca tatgatatga agaaacatct tcgaatcata
    39361 gcaggagctg ggagcggcaa aacgcaaaca atctgtgcaa aagctgttta tctgatgacg
    39421 caaaaacaag tagacgaaga acgcatacta atgatcactt ttacaaggaa cgctgcaaat
    39481 gaactaaaaa aacgagtaga taatttcagc cagagaaaaa ccgctgtcca tatcggaaca
    39541 ttccatagta tcttttttag gatatacaat gaaatttgtc gaaaatttcc tgaagtagca
    39601 atgcaaggaa tacaaggaga cttttcaaag gatactgcac aaaaagtgaa tgctgttttg
    39661 caacagctga tacgtaaata taatctttat atatttgatc aatatggaga aaaaacgatt
    39721 gcttctcggt tagactattg gcagaatatg aacctttcag tagaagaaat ggttcagtta
    39781 gttaaagaaa aatatgattc cattgataag aatgcacgac agccgatatc agaacgactg
    39841 tatggattgc tcacggaact ccaagaacaa aaaagaagcc agcaattgct agagttcaat
    39901 gatgtactcc aaaatctgaa aagcgctttg gagaatgagg agatccagca ttatatcggc
    39961 caaaaatatg attatctatt cattgatgaa tttcaagata ctaatccact tcaatgggaa
    40021 atcgtgaaac ggatgacaaa ggaaaacagg atcaagttga ttgttgttgg agatgatgat
    40081 cagagtatct atggattcag aggatcagag ccagcataca tcaagaactt tgaaaaagaa
    40141 tatcctacca aaactctttt cttattaact aattatcgtt ctcgggcagc tattgtccaa
    40201 ggagcaaata gattgatcag ctataataaa aatgatcgga taccaaaggc gatgattcca
    40261 gcacaaaaag aagcaggtgt tatggaagcc tatttgtttt ctgatactaa agcagaaagt
    40321 cagtggctaa tcaaacaaat tcagacattt attcaaaaaa atgggaaata taaggaatca
    40381 atcatattat accgatcagc ttcacaaacg cagcagcttg tccaatctct gctgaaaacg
    40441 aatattcctt ttgtactgga agcagatagt ccatatgaag gtatctttgg tatcaagtct
    40501 ttccaacatt tctatcaaaa aattgttcat tggcaaacag cactgaatct gcaaaagaaa
    40561 aatcaggcct accagcaatt gctccggcag ctgatggcag actgctacct gaaaaaaagt
    40621 gaatgcgatc aatacttttc tcctaaatat caaaatatag ccgttgcaga ttatattttg
    40681 tcgataagcc ccaatttaaa atcgaaatct gcagaaatcc gagagtttga ggaagcgttg
    40741 cgtaaaacag accagcatca agaaatctat tcgcttgttc aaagctatct tcatctgcca
    40801 cgtatagcta aggaaatcga ccagagtgat caagaatgga tacgagaaga agtaaagcag
    40861 catgctactt tcagaagact ccaagcctta tcgcaagaaa cccaagcgac agctaaagaa
    40921 ttaaaaaccc gcttgattgc ttacagacaa ggaaaacttg atgcactatg tatccagagc
    40981 attcacaaaa gtaaaggtct tagttaccga aatgtctttt tgattggttg taacgaagga
    41041 agtttgcctt ataacggagc gacagaaaag aaagtaatcg actttaatga aataaaagca
    41101 gaaccagtaa cgacgataga agaagaacga agactatttt atgttgcgat gactagagca
    41161 agaaatcgtc tgtatctatg tgtacctcaa atgaaaaatt caagaaaatt gaaagtatcg
    41221 agatttatca aagaaaccgg gagtcgtgtg aaaaaaggaa agtgatagaa gagagggtgt
    41281 gacagaagtg gtcagtttca agaaagaaga aggaatgtac gaaaattgct tctcaaattt
    41341 ttgtgaaatt tcagcttatt ttcgaagaag ctatttctgg aacacagttt attcggaaaa
    41401 gggaggtgtg acaagaattt tgtcacacct cccttattta ttttgaa
//
LOCUS       DACCVZ010000019        36569 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.019, whole genome shotgun sequence.
ACCESSION   DACCVZ010000019 DACCVZ010000000
VERSION     DACCVZ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.019"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="IVW63_000985"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="IVW63_000985"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAP7859275.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="IVW63_000986"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="IVW63_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAP7859276.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVDCREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="IVW63_000987"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="IVW63_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAP7859277.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="IVW63_000988"
     CDS             complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="IVW63_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAP7859278.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="IVW63_000989"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="IVW63_000989"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAP7859279.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="IVW63_000990"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="IVW63_000990"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAP7859280.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="IVW63_000991"
     CDS             complement(8053..8523)
                     /locus_tag="IVW63_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HAP7859281.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="IVW63_000992"
     CDS             complement(8569..8994)
                     /locus_tag="IVW63_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HAP7859282.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="IVW63_000993"
     CDS             complement(9061..9330)
                     /locus_tag="IVW63_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAP7859283.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="IVW63_000994"
     CDS             complement(9341..10936)
                     /locus_tag="IVW63_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP7859284.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="IVW63_000995"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="IVW63_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAP7859285.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="IVW63_000996"
     CDS             complement(14489..15049)
                     /locus_tag="IVW63_000996"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAP7859286.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="IVW63_000997"
     CDS             15402..16376
                     /locus_tag="IVW63_000997"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAP7859287.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="IVW63_000998"
     CDS             16546..17946
                     /locus_tag="IVW63_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAP7859288.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="IVW63_000999"
     CDS             complement(18024..18746)
                     /locus_tag="IVW63_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP7859289.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="IVW63_001000"
     CDS             complement(18825..19331)
                     /locus_tag="IVW63_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP7859290.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="IVW63_001001"
     CDS             19454..21253
                     /locus_tag="IVW63_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAP7859291.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="IVW63_001002"
     CDS             complement(21321..22895)
                     /locus_tag="IVW63_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859292.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="IVW63_001003"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="IVW63_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAP7859293.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="IVW63_001004"
     CDS             complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="IVW63_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAP7859294.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24672..25310)
                     /locus_tag="IVW63_001005"
     CDS             complement(24672..25310)
                     /locus_tag="IVW63_001005"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAP7859295.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25311..25961)
                     /locus_tag="IVW63_001006"
     CDS             complement(25311..25961)
                     /locus_tag="IVW63_001006"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAP7859296.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="IVW63_001007"
     CDS             complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="IVW63_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAP7859297.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="IVW63_001008"
     CDS             complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="IVW63_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HAP7859298.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29104..29844)
                     /locus_tag="IVW63_001009"
     CDS             complement(29104..29844)
                     /locus_tag="IVW63_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAP7859299.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="IVW63_001010"
     CDS             complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="IVW63_001010"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAP7859300.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31215..32153)
                     /locus_tag="IVW63_001011"
     CDS             complement(31215..32153)
                     /locus_tag="IVW63_001011"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAP7859301.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32146..32637)
                     /gene="def"
                     /locus_tag="IVW63_001012"
     CDS             complement(32146..32637)
                     /gene="def"
                     /locus_tag="IVW63_001012"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAP7859302.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32652..35060)
                     /gene="priA"
                     /locus_tag="IVW63_001013"
     CDS             complement(32652..35060)
                     /gene="priA"
                     /locus_tag="IVW63_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAP7859303.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35313..35618)
                     /locus_tag="IVW63_001014"
     CDS             complement(35313..35618)
                     /locus_tag="IVW63_001014"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAP7859304.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="IVW63_001015"
     CDS             complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="IVW63_001015"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAP7859305.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9886 a         7990 c         6705 g        11988 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgc gttctgaatt ctctacaatc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaatacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcttg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcattaacga tggattggaa gaaattgggc tttccttcat
    24421 tcgctcgctg cgcagcggtc acacttagta tcgtcaccac gatgataaca ataaccaagg
    24481 taataataat atttttatta ggattgaact tcttcacaaa gacacctcga attaattaga
    24541 ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa aggtaagttg ctcctcttaa
    24601 gctttttttt agcaaataat agattctgtc atttttagcc tgaaagacaa atttttttat
    24661 ttgtttatgg atcaatcttt gctttgaata actgcaatca taccatctga aaaagaaaat
    24721 tctgcggtat ctgaaagaaa ttcgttactt gcataagatg tcggatattc tacttcttta
    24781 ttttccaata catacttgct gccttttaat gtaagattcg agacgggagt caagcagcaa
    24841 taagctaaat acttcatatc tggtatctgt cttactatat gctctccagg caaataataa
    24901 gacaaataat tttgacaatc tctgataata agctgatggg caaagggttt gaagcgaggt
    24961 tccataccta accagagatt ggctaaaaga tgatccaatc ttccgcccgt agctccaatc
    25021 aaagtgactt ccgcttgcgg gtaacgttca aatgttttta agatacctaa ctgtgtatct
    25081 gtatcgtctt tttctgcagg ggaacgggta tactctttgg cttttgcaaa tacttccttc
    25141 tgctcttcgt tcgacaatga atcaaaatcg cccactgcca gatctactgg gtagcctgct
    25201 tgaagcaggt acagcgcacc acggtctatc ccgacatagg catcgtattt ggacagcaga
    25261 gactgcggcc agttttgcgg attacctcca gcagctaata aaattttcat ttagtctaat
    25321 gcctctttta atcgttcgat ttgtccgact ggattttcgg ctccatagat atatgatcct
    25381 gcaacgaaga catccgcccc tgcatcttta cagatttttg ctgtttctgg aacgattccg
    25441 ccatctactt cgattgcata agtccaattg ttctctctac gtagatcagc gagttccgta
    25501 attttttcta ctgtttcttc aataaagctt tgtccgccga acccaggatt gacagtcatg
    25561 actagtactt gatcagccaa aggcaaaaca tgtttgatca tggagactgg tgttcctgga
    25621 ttgataacta ctccagcttt aactcctaag ctttttgtca tttgaagtgc ccgatgaata
    25681 tgaggagttg cttcgacgtg gacagtaatg atatctgctc cagcttttgc aaatgctgga
    25741 atgtagtttt ctggatcaac gatcatcaga tggacgtcta acggtaattt agtaacagga
    25801 cggattgcct gaacaatatt tggccctaat gtgatatttg ggacaaattg gccatccatt
    25861 acatctacgt ggatgtaatc tgcgcctcct ttttccacta actcaatgtc tctttgtaaa
    25921 ttggcaaaat ctgcactcaa aatggatggt gctatcttca ttcttgtttc ctcctatttt
    25981 cgtttacctt ctttttttgc atacattggt tttctttttt cgatttcttg taagaattgc
    26041 aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt ctactctatg ttttacttcg
    26101 cagccaggtt ctttagcatg catgcactct ctaaatttgc aatggacaga agcttctaca
    26161 aattcaggaa attgtctcgg cagttctcct gcttcaattg tcaaaaagtc aatcgagcta
    26221 aatcctggtg tatctgctac taacccgcca tagataggaa tcagttccac atgacgtgtt
    26281 gtatgccgtc ctcttccaag tgcatcagaa atctctcctg ttgctaaatt cagttccggt
    26341 gatatttgat tcagtagcgt cgattttcct gctccagact gacccataaa gaccgatagc
    26401 cgttctggga agtaacggat cagttctgtc gtatcacccg tatgattggg tacaatcacc
    26461 ggatagccta ttttagtata ggtttgcttg atctcttcga ttttttctgg gtcgtctgac
    26521 aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact cgtattccaa ggtaactaga
    26581 aagcggtcaa gtagattata agaaaatgca ggctctacga tacttgtgac aatgattcca
    26641 agatcaacat ttgtgactgg tgggcgaact aattgatttt ttctcggcaa gatttccaga
    26701 agatagccgt ctgtttgatt ttcactctca aagatcacct gatctccgac aagcggcgtg
    26761 attttccgat tccggaaatt tcctcttcct cttgtttgat aggtctctcc gtttgcgtat
    26821 acatagtaaa aaccgctgat tgcttttctg atttgtcctt tgataagtgc cacctccgtt
    26881 tttgtttatt ttaccatacg aagaggaaag taggtgttat tccatgcaaa cttctcaaag
    26941 tatatggctt gaaaattgat caaaagagat agaaacacaa aaaagagaat gcaacaaatc
    27001 aatgtcgcat tcccttctga tatattttat tcagcactta ttttgaactt tctgaggtgc
    27061 tagctgatga acttgtggag ctggaagatt cttcttttga agagttgctt gtgctactgg
    27121 agctacttga gctgctagaa ctgtctgaag agtctttttc agaactagaa gacgctggat
    27181 ctggtccttt agagtaaatt acgttcacaa ccattccttt ggtaattgtc gttcctgccc
    27241 ctggtactgt acgaatcact ttatctttat ccaccgtgtt tgaatattcg gaagtctcat
    27301 gcccgatata ttctgcaccg acactagcta aataactttg tgcttcgctt tttgtatagc
    27361 cggagatatc attcaattta ggctctgttc cttggcttac gacaaaattg atgtaagttt
    27421 cttctgctac aacttcaccc gaggctggat cctgactgat gatcgaacct gatggtacag
    27481 tgtcgctata gtcataagta gcactaatat tattgatatt gaatccttgt gtaacaagcc
    27541 aattacgaac agtttcgtag ttttctccta catgactact caaagtcact gtttctggtc
    27601 ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc gacttctgta tcttctgatg
    27661 gagattgcga aatgatcatt ccgctttcta cctctgaact gaattcctct tctttttgaa
    27721 tcaagtcagc agaaaaccct aattctttca aacttgcttc ggcatcttca taacttttac
    27781 cactgtaatc atctaatttg atttttttcg tgccgctact aatatacaga gtgacttcgc
    27841 gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt cactacatta ccttcttcga
    27901 ttttgtcatc tgcaatttct tctgtttttg ttgctacttc taatttcgct tttgcgagtg
    27961 tttctctagc agaagcttca gaaagatcag aaacatcagg aacaacaact tctcctcgcc
    28021 cgccagaagc aaagaataca gctgttccga ttcctaaaac agcaagaata gctaatagga
    28081 tcagccacca ttttttctgt cctttctttt taggatcagg cagaacttct tcctcctctg
    28141 gcaaggtttc gttttctggc ttgtcttttg gcagaggcat agatttgaat gaatcaggca
    28201 ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc attatccatc acatgaggct
    28261 gccatttttc ttcgtttgca cgagctggtg ataatactgt agaaagatca tcagacattt
    28321 cctcggctga cttataacgg tctgcaggtt ctttagccgt tgcccgtaaa atcacgtttt
    28381 ccagtgcttg tggcacattt ggatcaagtg cttttataga tggaagatca tcttgaaaat
    28441 gttttaaagc aattgttaca gcagattcac catcaaacgg tacgctaccc gtcaacatct
    28501 cataaaggat gatccctaaa gcataaatat ctgactgctt cgttgccata cttcctctgg
    28561 cctgctcagg ggacagataa tgaacagatc ccagcatcgt attcgtctgc gtgatcgatg
    28621 tttcagataa agcgatagca atcccgaaat ccgtgatttt tacaacacct tcattatcga
    28681 tcagtacgtt ttggggtttc aaatctcggt ggatgatttg atggttatga gctaaagaaa
    28741 tagcagaaag gatctgctgc ataatattta ctgctgtttc ataaggaaca ggataatgtg
    28801 tttggatata tcgtttcaag tccattcctt tgacgtattc catcaccaga tactgcatgt
    28861 tgtcttcttc accaacatcg taaacactaa caatgtttgg atgaacgagt tctgttgctg
    28921 ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc attttgaaag tcaaatcgta
    28981 agactttaac tgctacatca cgatccaaga ttaaatcgtg cgccaaaaat acatttgcca
    29041 taccaccgct accgatattt ccagtgattt gataacggcc atttaatttt ttgcccaact
    29101 cgatcataca ctgtcctcct tatattcgat aagaagaacg gtgatattat ccgctccgcc
    29161 tgcttcattg gcacgatcaa tcagctcagt tactttatga gacaatgggc cttcttgatt
    29221 gatgatcgtt cctatttctt cttcagacag catgttcgtc aagccatctg aacataacag
    29281 cagtcgatct tttagttgcc aaagatgagt agaaacatct acttcgactg ttccaggcat
    29341 gccgacagaa cgtgttaaaa tatttttcct tggatggttc actgccattt cttcgctgat
    29401 ttctcctgat ttgactagtt cattgactaa agaatgatcc tccgtcaatt gcatgatttt
    29461 atcttcacga atcaaataag ctctgctatc cccaacattg gcaatcgtga accagtcatc
    29521 tgacagagcg gccgctacga ttgttgttcc cataccgtta tattccggct gttcttgtcc
    29581 acgctgataa atcagcatat tttcttcttg aatcgattga atgaaccatt gggcgatttt
    29641 ttcatcgtca acagcttctt gtttttccca agcttcgcct agattcgtta ccgccatctg
    29701 actggcaatg tctccggcac gatgaccacc catcccgtct gctaatacag caagcttgag
    29761 acctgaacgg ctggtaaata cactggcata gtcttgattt gtgttacgtc gtcttcctac
    29821 atctgattga tattcaatct gcattttttc acctcattac tttttgcgca aacaacaaat
    29881 gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc aacattttct cttcgattga
    29941 tgattgtagc ataggattgg tcaaaacatc aatcctctca aaatcagggt gtctttccaa
    30001 gaaagcagaa acaacgtctt ggttttcttc ttttaagatc gtacaagtgc tataagtcag
    30061 aataccggaa gactttaaag ttggtgcgca gctttctaaa atttccaatt ggatttttgg
    30121 taaattcgct aattcatccg gctgtttttt ataacgaata tctggttttc gccgaagcag
    30181 cccaagacct gaacaaggcg cgtctactaa aatccgatca aactgctctg cttcgaactg
    30241 tttactgact tctctagcat ccatcttttg agcgtagaca gcagaagaga cacctagacg
    30301 tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt acatctaaag cgaccacttc
    30361 tccaccgcat gacggatcta aaaaagaagc aatatgcgtc gtcttacctc cgggtgctgc
    30421 acaggcatct aagacatgat gttcaggctc gatttgcata gacggcgcta caagcatcga
    30481 actttcatct tggatcgtca tgacgccatc gtggaacaat gagctagaag ctaaatgccc
    30541 ttttttcgct actataccgt atggactgac ttggcttttt tcagctgtga tctcttcttc
    30601 ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt gtatctactc gggcactagc
    30661 atggctaggc tgatatagcg ataaaccgag cttttcagtt tcttcgtatc cgatttgatc
    30721 caccagtcgt ttcgtcatcc atagaggcag gctgattttg acagaaagtc tttcgatagg
    30781 atcagcaatg ccttgcagat ctggtgctcc ttgacgctga taattcctca agacaccatt
    30841 tacaaatttc cctgtcccag gatttccttt tacttttgcg atttcgaccg cctcgtttaa
    30901 aatagcatgt gcagggactt tatctaaaaa ttctaattgg tatacagaaa gataaagaag
    30961 cgtcttgacc cagtcatcca ctttttttgc tttagcgatc aatggtgcaa cgtaaaattc
    31021 caatagtcgc tgatggctaa tcgtaccata gatcaattct gtaaataaac ccacatcttt
    31081 ttgatttagc tcgctttgtt tgatcatctc attcaacaaa agattcgagt aggcgccacc
    31141 cttgttcact cgctctaatg tcagtaatgc catatatcgt actgattttt tcattttttt
    31201 agggattttt ttcattattt cacctgctga ccaatctgaa cttgctgacc gcttccgtta
    31261 aggaaatcat gtacggcctg ttttccttta ccagctggct gtaattcatt gatggctaag
    31321 acggtctgtt taccgcaagc aatccataga ttttttttgt ctttccggat gatcgtacca
    31381 ggtgctttgt ctgtagtttc tgccaatact tcaaccgata ataatttcca gcgtatgccc
    31441 tcataggtcg tgaatgcaat tggccaagga cgcattccgc gtacttggtt gtcaatttct
    31501 tctgcagttt tatgccaatc gattgcttct tgttcccgtg tgatgtttgg cgaaaaagtt
    31561 gcttctgact cgtcttgagg tactggtttt tgtccatcca aaatattggg caatgtttct
    31621 agcaatagct ttcttcctaa aaggctaagc ttttcaaaca tcgtccctac atcatcttgt
    31681 ttagtgattg gtatgctttc ttgcgcatag attccgcctg catccatttt tttgatcatt
    31741 tccatgatcg ttacaccagt ttctttctcc ccattcatga tggcataatg aacaggcgca
    31801 cctccccgat atttaggaag taaagaagca tggacattga ttgcccctaa ttttggtact
    31861 tgcaataact tttcaggcaa gaattggcca aatgccgcag tgacgatcac atcaggcacc
    31921 aattcaatga tttcttccat ttctggcgaa ccggagattt tctctggctg cagcacacgg
    31981 ataccgtgct tcagagccgc ttcttttacc ggtgtcggcg taattactcg tttccgccca
    32041 actggacggt cgggctgtgt taccactgcc tggatctcgt aacctgattc tatcagccct
    32101 tcaagaatcg gcacagaaaa agcaggtgtg cccataaata ctagcttagt catcaagatg
    32161 ttcctccata tattcttcaa gttcttcttc cgggatctgc tgtatcattt tctcaatgaa
    32221 caagataccg tctaagtgat cgatttcatg ctggaaggca cgggctaaat agccaaaagc
    32281 cgtcacttct atctcttctc cgtctcgatc ataataacgc acggtcactt catctgctcg
    32341 cttgaccgtt ccatagacat gcggaatact gagacaacct tctacgtcaa ggctttcacc
    32401 ttttgcttcg atgatttctg ggttaatcag ttcaaatttc tcgccttcat ctacttcgat
    32461 cacagcaatt ctcttgtttt gtcctacttg aggagcagcg atccctattc cgtcattcgc
    32521 aatcattgtc tcatataaat tgtctaataa agcgattgtc tcgtccgtga ttacatcgat
    32581 tggctgagca gttcttttta atttatcatt agggtggatc aatataggat agcgcataat
    32641 ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa ttgccacaaa aagaccttgt
    32701 cgctgttctt tctggcttcc attcaaaatt tcatccaaaa catgaggaag attcggttca
    32761 tgtttatatt tgatgattag ttgataataa tatcggtttt tcactctcaa aatcatgctg
    32821 ggcgttggcc ctaatagcaa gctttgaggg cttaacactt cttttagctg attggcaatc
    32881 tgaaagattt tctttgccgc tacttgttct tcaggatggc tggcggttat tttcacagta
    32941 aagtaataag gaggatagcc tccacgatgc cgtacatgca tttcctgctg ataaaactgc
    33001 tcataatttt gttttttagc taattctatg gcgtaatgtt gaggattgaa tgtttggatc
    33061 acgacttcgc ctgctttttc cgctcgccct gctcgtcctg aaacttgggt aagcaattgg
    33121 aatgtatgct cactagaacg aaaatccggt aaattcaggg aggtatcagc attcaacacc
    33181 ccaactaatg tcacttctgg aaagtccaaa cctttagcaa tcatttgtgt ccctaataat
    33241 atatctgctt cttttgcacc gaatttttgt aaaatctgtt cgtgtgcccc ttttcttcga
    33301 gtggtatcta catccatacg caaaatccta gcttgcggat aaagttctcg gagttcctct
    33361 tctacttttt gagtacctgt tccatagtag cggattttat tgccgccaca attaggacag
    33421 cgattgggaa taggttcttc atgtccgcaa taatggcagc gcattgaacg tgtatccata
    33481 tgcagtgtaa gagagatatc gcaattagga catggaagaa caaatccaca gtccctacac
    33541 atcacaaaag acgaatatcc tcgacgattg agcagtagga cagtttgttc ttttttgtct
    33601 aatcgatttt gtattttttc ctgcaaatta gcagaaaaag tagaggtccg atgattctga
    33661 aactcttcac gcatatctac gatctcaata gctggaagct gtgcagctgc tttggctcgg
    33721 tggtttaact gcaataactg ataaacgcct ttttgagctc gtgctcttga ttctaaagag
    33781 ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt tactgcgcca aattgctaga
    33841 tctctcgcat gataacgcgg tgtctcatct tgtttgtaac ttgattcatg ttcttcatcg
    33901 ataatgatca gcccgatatt tttcagcggg gcaaaaatag cagatcgtgc gcctactact
    33961 acttgcgctt cttcccgctc aatcttgcgc cattcatcat atttttcacc ttgggaaagt
    34021 ccgctatgta agaccgcaac tgattctccg aagcgtcctt tgaatcgctc gaccatttgc
    34081 ggagtcaatg cgatttcagg cactaacata atagccgttt tattttctga caaaacatca
    34141 gcgattgcct gaagatatac ttctgttttc ccgctgccag tgattccctc cagcaaaaag
    34201 acctgatctt tttgctgctg acctgctgtg atgatttgtt cgacagcatt tttttgttct
    34261 gcattcagtt ccaatgccgt cgtttggtca aatactcggt ctttataagg gtcgcgataa
    34321 cgttctgatt ctataaactc cagccagccc ttttcttttc cttgattcaa gacagcagta
    34381 ctgattcctt tatttttgaa ataagcaatt ggttcttctt ggctcagttc agataaacac
    34441 aaaagaagtt ctttttgttt cttggcattt tgccgtaatt ttgcccattc ttcttcgatt
    34501 tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt ttactttatt tcgtgtatgg
    34561 acttcatatt tgatatctac taattgctct tggcgccagc gaatcaattg agaaaggctg
    34621 ccttcttctt ctgcttcctt ccaggaaatc acttctcgct gatcaaacaa tacctgaact
    34681 tctggtgtgt ctgccaaagg atagatcaat ttatcatatt ctgctttcat cacactcgga
    34741 agcatcgttt gtagacaagt gattttgaat gcgtaagtaa tttttttcat ataatcagct
    34801 aatgaaagta attcttcatt gaccaccgga gcaaggtcta gcaaacgaat aactgccttc
    34861 aaagatggat tagctgattc ttctgatttt tggatagcca taacaaatcc ttggacatga
    34921 cgattgccat taccaaaagg gacttctact cgcatcccga cttgcaaagc tgtttccatt
    34981 tcagagggaa ccaaataagt gaatggctga tcggtctgca tagtaggtac gtccacaatg
    35041 acttcagctg ttaatgtcat ggttcgtttc ctcctttttt tgtcttttct tatcaagcga
    35101 caaaaagttc cttgcctatt ttactagaga tcgatggatt tgtcttatct tctgccaaat
    35161 cctaacaaaa aattaacagc agataagaaa aaaaagaact gtgtcaaaaa gttcagacac
    35221 agccttttct accagacaat aagtggcgaa tgtttgaaaa ggaaacagct gggtttgctt
    35281 ttctttttag atgttcgctc tatttttctt tattacattt tttgctcttc acggatacgt
    35341 gattccaatt cgtgttgttc acgctctttt tgtgcttgac gttcctcttc ttccatcttc
    35401 aaacgttcac gttttaattc aggatgtgga tcattgacta catttcctgc atcgatttct
    35461 tctaaagctt gaccgacgct ttttactgaa tcaaaagaat ctagagtagg ctgtgcactt
    35521 gcatccaatt catgcgcgcg tttacttgct aaaatcacta gagaatattt tgaatttaca
    35581 cgatctaata gtgagtcaat tgaaggtttt aacatcataa gactacatct cctttaacat
    35641 tttaatatat ttaccgatta cgcgatctac tcgaaaatgt tcactggcaa taatgttttt
    35701 gattcgttca actgctagcg gcacttcatc atttacaaca gcatagtcgt aaagagccat
    35761 catttcgatt tcttcttttg caactttcat tcgttcttcg attacttcat ctgcatctgt
    35821 tcctcggcct acgatccgtg attttaattc cgctaaatct ggcggagtca aaaagatgaa
    35881 tacaccatcg ggcacttttt ctttgacttg ttttgctcct tggacttcaa tctccaagaa
    35941 aacatctttt ccttcatcca atgtcttgtt gatatatgac aaaggagttc cataataatt
    36001 cccgacatat tctgcgtatt ccagcatctc tccagcttcg atcattgatt caaactcttc
    36061 tttgcttcgg aagaaataat caacgccttc gacctcccct tcacgcattt tacgggtagt
    36121 cattgagatc gaatactgaa aatcattatc ctcactctca aaaattgctt ttcgtactgt
    36181 gccttttcct acaccggatg gaccagacaa cacgattaat aatccacgct ctgacatgac
    36241 gacgtccttt caactagtct ttttgtactt atcgtttatt ttgcactttt tttctgcaac
    36301 tttcaaggtt atctttaatt atagctagaa attggtaaaa aagctaccct gtaccaagag
    36361 gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc caaacataaa cagcttctca
    36421 tgtttttcgt ttggttgggg ttattatcgc agatgcaagc ttttgaacgc cgtgtataag
    36481 aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa attttgtgaa aatagtttct
    36541 cacatttttg cataaatttg gcttaatac
//
LOCUS       DACCVZ010000020        36329 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.020, whole genome shotgun sequence.
ACCESSION   DACCVZ010000020 DACCVZ010000000
VERSION     DACCVZ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36329
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.020"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(22..1605)
                     /locus_tag="IVW63_001016"
     CDS             complement(22..1605)
                     /locus_tag="IVW63_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859306.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALI
                     LDLIDKLSDLANIYEDNTSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLSYGNEE
                     ADRDRESTFRLLNALIFDNKEFYLNILKKEIAKYRFTAESREEINKSLGENQQITYTK
                     GFFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGNN
                     NEELQNHLNSLVDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADKDMEVLPWIYNKLNQEQFNKLLYNLNGNNQFYKNSNFPPFISNLLDFYNQKF
                     QVNLRKHYSGLLYPNAVTMDQGFQLKDKELKKLYELAESKSDMYLDIIDNIINKSEDY
                     LRKEINSEKELLNYVHKIK"
     gene            1727..2311
                     /locus_tag="IVW63_001017"
     CDS             1727..2311
                     /locus_tag="IVW63_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859307.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            2322..2567
                     /locus_tag="IVW63_001018"
     CDS             2322..2567
                     /locus_tag="IVW63_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859308.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            2573..3295
                     /locus_tag="IVW63_001019"
     CDS             2573..3295
                     /locus_tag="IVW63_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859309.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSANNNKDTKSSSTMVTKN
                     STTSASTTMSSMTENNAEKYQKYEDINKGQKPDEVYNNFINTVKNDENYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYYAVAVDITDGV
                     PEWVQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            3426..4169
                     /locus_tag="IVW63_001020"
     CDS             3426..4169
                     /locus_tag="IVW63_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859310.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKATSIRELRSEVEKIRLGLTSEEIAKLKGNNSFVIEKEKEKHLLYRELKIEEYYEI
                     DLPEKLRIIDQRSEEKWKTEIYPSLNDYKTSGKPMYNYTGFLTYTQYKYAFRKLKGIK
                     QAEIALYEMKKVDRLKLIQDLVQNTWNQAIVELEKENGKILTNKYLIVNEIEELIGLF
                     SCEKGEVFLKSSPTYSILDSPYQFIQARR"
     gene            4175..4540
                     /locus_tag="IVW63_001021"
     CDS             4175..4540
                     /locus_tag="IVW63_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859311.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDRQFNQIHHNIILLVEQAKRRFEKAEYDLLDQGIVCLDKGLRRYYGAELKKQ
                     NVDRNALKHEILELIMQRI"
     gene            4556..5086
                     /locus_tag="IVW63_001022"
     CDS             4556..5086
                     /locus_tag="IVW63_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859312.1"
                     /translation="MSQNISAVKQLIEEDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAKEKSSILELSQ
                     NDKVIQVKCVDPTGKIIVGFDIERKSKIDFITQLKKINNLDILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFPNA"
     gene            5248..5556
                     /locus_tag="IVW63_001023"
     CDS             5248..5556
                     /locus_tag="IVW63_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859313.1"
                     /translation="MWNNRLKTGLLLIVISCAMMIGMRIQREQSYFEVSANNVIEKCY
                     YGQHYWSEEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSDLMMKKV
                     "
     gene            5552..5971
                     /locus_tag="IVW63_001024"
                     /pseudo
     CDS             5552..5971
                     /locus_tag="IVW63_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352869.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6108..6908
                     /locus_tag="IVW63_001025"
     CDS             6108..6908
                     /locus_tag="IVW63_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859314.1"
                     /translation="MSEDLRELKLRKKQYDQYFSGLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSMSGYVESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSEEEVRELVETPVRKKVETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYDSKRFERLEKFCRPYTVLKTKKFNKTKRVS
                     IQLPTGQISLGEKDYLIKVGKELIIKVPEHLFKENFEIRETLVWKEEK"
     gene            6945..7127
                     /locus_tag="IVW63_001026"
     CDS             6945..7127
                     /locus_tag="IVW63_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859315.1"
                     /translation="MAVNKILQVLIIDEFGGGEWFDVQSIDFEEEVVVIENIYGEVYS
                     YSLEGENIEDLRLIGE"
     gene            7238..7555
                     /locus_tag="IVW63_001027"
     CDS             7238..7555
                     /locus_tag="IVW63_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859316.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            7558..7790
                     /locus_tag="IVW63_001028"
                     /pseudo
     CDS             7558..7790
                     /locus_tag="IVW63_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7905..8384)
                     /locus_tag="IVW63_001029"
     CDS             complement(7905..8384)
                     /locus_tag="IVW63_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859317.1"
                     /translation="MTDKTSDLPKLAPKTSRVKSKKDGKTKNAVKKKSVKETSSLLLD
                     IPMSSFDDNTDETSVKIATHVGMNNQNDSFYNLLNSLRELEDKKNQVIASKAPDLTTD
                     LDAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            8504..9841
                     /locus_tag="IVW63_001030"
     CDS             8504..9841
                     /locus_tag="IVW63_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAP7859318.1"
                     /translation="MLMVQFTGIAMSVITINPQVIHADGIATYDAQFNCTTEGSGSGT
                     DSDGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRAVEG
                     YYGDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMF
                     KGDGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMK
                     SKGMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEG
                     KINGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFNGIYQGQCTELTWAYMS
                     QLYDGNQPTTGNGGYVWESYKSAGAKITNKPIVGYGFSASDGWLWAVGDAGHTGVVIA
                     VFEDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            9864..10391
                     /locus_tag="IVW63_001031"
     CDS             9864..10391
                     /locus_tag="IVW63_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859319.1"
                     /translation="MNSKVKDTIIISLLSGMLLALLVGILFFNKQNQDIEAEKHSVHI
                     EDKLTFFKEVKPNEVDGLRKDLENDIQEMLNGSVQNKFADQSGEEFLRKLFIVTGKPP
                     ITDKSSEKEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            10378..10941
                     /locus_tag="IVW63_001032"
     CDS             10378..10941
                     /locus_tag="IVW63_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859320.1"
                     /translation="MQNHEITTAKKAIGILSIIVILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            11363..12100
                     /locus_tag="IVW63_001033"
     CDS             11363..12100
                     /locus_tag="IVW63_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859321.1"
                     /translation="MADHKLEKLLEETWNPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENKGTWDFWATLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISELGGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVKITNKLDYGSWADIALEKYIYSTLKEFIENRMDIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(12117..12533)
                     /locus_tag="IVW63_001034"
     CDS             complement(12117..12533)
                     /locus_tag="IVW63_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859322.1"
                     /translation="MNKKRKLSVLITLVSILTILSVILSLKIFNQINTSSNAKDGIVV
                     ENTSNSKETGTTTKKDKSAEITTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKNDELYSFVK"
     gene            12926..14173
                     /locus_tag="IVW63_001035"
     CDS             12926..14173
                     /locus_tag="IVW63_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859323.1"
                     /translation="MNMKRNSLGMVLLASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNISK
                     DTLTVKEADGEVVSQTVQKDKPDPIENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSKPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKPMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            14441..16831
                     /locus_tag="IVW63_001036"
     CDS             14441..16831
                     /locus_tag="IVW63_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HAP7859324.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMMLSTLIMPFSAIRAEADVTKPT
                     SAKFIETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGVFKQEGITVKDDGQTFEYTATNTLKKGLVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGITVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDRNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDGQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            16880..18715
                     /locus_tag="IVW63_001037"
     CDS             16880..18715
                     /locus_tag="IVW63_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP7859325.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANRTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKAVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            18790..19647
                     /locus_tag="IVW63_001038"
     CDS             18790..19647
                     /locus_tag="IVW63_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP7859326.1"
                     /translation="MKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNSYK
                     EKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNGNLQKDKLGELVG
                     EILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKYFT
                     DLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVGDN
                     SHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKIVA
                     KRRGMKNEE"
     gene            19637..20746
                     /locus_tag="IVW63_001039"
     CDS             19637..20746
                     /locus_tag="IVW63_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP7859327.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDKGVDNTQETDGGSFDIREAEGKVNPY
                     TGDVFSKNQTKDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLP
                     LSGKGHQTVIAGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQ
                     NSTLTDIPDLDMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDS
                     ESVSDKTETVTSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTG
                     ITNKHQKMLLVIWTVIGALASLKVLILLIKEFRKA"
     gene            21085..21885
                     /locus_tag="IVW63_001040"
     CDS             21085..21885
                     /locus_tag="IVW63_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859328.1"
                     /translation="MVGISKTALDSLAKLFSSRFDGAEFVEYLSQNESGKTLIETMKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLIGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYANDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            21973..22779
                     /locus_tag="IVW63_001041"
     CDS             21973..22779
                     /locus_tag="IVW63_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859329.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVGEENIEFEIKNMDDLKAKFPFIASKLSQVAEDKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYLVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            23011..23880
                     /locus_tag="IVW63_001042"
     CDS             23011..23880
                     /locus_tag="IVW63_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAP7859330.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     IGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAVNSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            23900..24247
                     /locus_tag="IVW63_001043"
     CDS             23900..24247
                     /locus_tag="IVW63_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859331.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMVIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            24260..25522
                     /locus_tag="IVW63_001044"
     CDS             24260..25522
                     /locus_tag="IVW63_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859332.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            25602..26978
                     /locus_tag="IVW63_001045"
     CDS             25602..26978
                     /locus_tag="IVW63_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAP7859333.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTVMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMLIKLVDGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAETRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANPSSKEPSIEKKSAFAIKLEKNKEEKANQGAKSLEKLQQEKLEKLEKALSS
                     STSETQSSKGIDNGQSITTKNKPKNSNSNLSVNVVITTDKSEKKQVNGTTSPIMQKMI
                     KAKKQVQK"
     gene            26975..27604
                     /locus_tag="IVW63_001046"
     CDS             26975..27604
                     /locus_tag="IVW63_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859334.1"
                     /translation="MIIISSFLRWLTPYKYTDEIVEKRAKKKVKKTMLTPKEMLDRGI
                     LGVKVLEVNQPFELDNARDRLLRAEVDVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLKPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSSQNRVQINKFEKKVRK
                     FNDRKIILWFANIQKQPDGTAKWEAVIFDEDGKKVMSEVWHDKAKFVWQ"
     gene            27616..28086
                     /locus_tag="IVW63_001047"
     CDS             27616..28086
                     /locus_tag="IVW63_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859335.1"
                     /translation="MLTNLKLYREGFNEKVSIGESIEYLGKKYIIIRILEIKKLYFSK
                     YNNLAVRVLVQKVGNPSDYRSDYHNYKTESSVIKRYNQSKNDERIFKVGEIIISKYGI
                     AYEIVSIKKFYYEFVDLVVEYSVRLIVPWSKEEINEALKHERKSTFKVLEGEKK"
     gene            28083..28565
                     /locus_tag="IVW63_001048"
     CDS             28083..28565
                     /locus_tag="IVW63_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859336.1"
                     /translation="MKTDLTRQAEKCLWHETNRMGVFGCFEVTIGWDGSERVDYITYS
                     VDNTVRCYEIKVTLADLKSKAKQTFIGDYNYLVVTSDLWEKMQQDDKLMRKYYYQGVY
                     VFNEKYPSIISVKKARKQKVSLGTRSTVLESMVRSMNREVKKLYKVKPFWEIAEVEKG
                     "
     gene            28562..29224
                     /locus_tag="IVW63_001049"
     CDS             28562..29224
                     /locus_tag="IVW63_001049"
                     /inference="COORDINATES: protein motif:HMM:NF019467.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290663.1,RefSeq:WP_002351343.1,
                     RefSeq:WP_010747081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAP7859337.1"
                     /translation="MIQTFAKMSRSAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVELDEPKKSVDVPENVAELLDYYRNSSDVDLLALILTFHDWYYCQNEDTQHDKHD
                     KAVDWLIENPEKFMRAWLDGYDSKKKPLESNEETYLTAEQYDYARKTGDWESGKTFNH
                     RKDQPKISFSDIAAIIEGIYYGQADEEIFSIQDLLEFLNKNKDSFVELTDYEEDTANG
                     KL"
     gene            29211..29579
                     /locus_tag="IVW63_001050"
     CDS             29211..29579
                     /locus_tag="IVW63_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAP7859338.1"
                     /translation="MENYDPNMRWGTHTLKVSFQRWDYKGFVTFRKAGNCKGLDVLAL
                     DEDYLYDHPLTDNPIGFGLLPEDDEGNEWFKMILTNDKGDQLFVEDTWSYLSEYIVSI
                     KIIDFVADKEKEIGEGKSNY"
     gene            29660..30112
                     /locus_tag="IVW63_001051"
     CDS             29660..30112
                     /locus_tag="IVW63_001051"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859339.1"
                     /translation="MIVSAVTIYWLGNQQNSLIVDLGELKVGLRMTRWLLLAQTVGLA
                     ILTWICVEKITSNNNQEIVESTNLRIRITEQAIEKQKDKEKKEIMSIYLSSGASFFHE
                     IDSMKLSSQEIIDRWKNMPLGGELIVEDSDGWSAYKKDEIVAITILFE"
     gene            30764..30817
                     /locus_tag="IVW63_001052"
                     /pseudo
     CDS             30764..30817
                     /locus_tag="IVW63_001052"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            30821..31420
                     /locus_tag="IVW63_001053"
     CDS             30821..31420
                     /locus_tag="IVW63_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAP7859340.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGLLGSLVPFLLQSNIVSMGLSGGIFGWIALFAIAYIRFDSKEHLLLSVFILLIIGIL
                     LVSTFESGETNVLSHVIGFVCGMILGFILKNISLIKQKN"
     gene            31436..31912
                     /locus_tag="IVW63_001054"
     CDS             31436..31912
                     /locus_tag="IVW63_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859341.1"
                     /translation="MPKKKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNNEDESKLGLAQQRIFEWLNTNTEQEPLRAISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSKDSKSMRDLLITYLNEHEFEQTKTKKKNKE"
     gene            31929..32831
                     /locus_tag="IVW63_001055"
     CDS             31929..32831
                     /locus_tag="IVW63_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859342.1"
                     /translation="MLLTLLGYLCLILAFFGAIAIIIGQFQTNNPIMRNIGIGIVIVT
                     FIVFNATKIFGSNDKQFGISGVNNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNSVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGADLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            32904..33095
                     /locus_tag="IVW63_001056"
     CDS             32904..33095
                     /locus_tag="IVW63_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859343.1"
                     /translation="MVVNKEKVRKYVTLKIASVKYLEKRAKEEERARGKKVTVSELLE
                     ELIENDQTIRRAFTNRSIR"
     gene            33259..33846
                     /locus_tag="IVW63_001057"
     CDS             33259..33846
                     /locus_tag="IVW63_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859344.1"
                     /translation="MENNNDIRHFSIGERVTTVSELSKDYRDKEGTIISLNKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNNGSHSIEKAILVYPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITSKEAKIEDVLTVRELQSLIEYRNKQITNPEYLRKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDTFKKIYLKEIKKD"
     gene            33846..34745
                     /locus_tag="IVW63_001058"
     CDS             33846..34745
                     /locus_tag="IVW63_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HAP7859345.1"
                     /translation="MWTVTLPFQPVSAPRPSARRNAADETNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQDLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            34745..35659
                     /locus_tag="IVW63_001059"
     CDS             34745..35659
                     /locus_tag="IVW63_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859346.1"
                     /translation="MNNNEKILHVLDSFEIIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKNAMELNEERRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYGVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            35711..35926
                     /locus_tag="IVW63_001060"
     CDS             35711..35926
                     /locus_tag="IVW63_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859347.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLKQFWLNNFSYKDFIKEKANTLY"
BASE COUNT        13614 a         4932 c         7212 g        10571 t
ORIGIN      
        1 tgcatcttgt gttataaaaa attattttat tttgtgaaca taatttaaca attctttctc
       61 ggaattgatt tcttttctta aatagtcttc agacttatta ataatattat ctattatgtc
      121 tagatacata tcacttttcg attcagctaa ttcatacagt ttttttaatt ctttatcctt
      181 taattgaaaa ccctgatcca tagtcactgc atttggatat agaagcccac tataatgttt
      241 acgtaaattc acttggaatt tctgattata aaagtctaac agattagaaa taaaaggcgg
      301 aaaattactg tttttgtaaa attgattatt tccatttagg ttgtatagta atttgttaaa
      361 ttgctcctga tttaatttat tgtaaatcca tggtaatact tccatatcct tatctgctaa
      421 cctgaatgaa ctagcatcgg taagatgttc gatcataaaa tctatgaaca tctctttttc
      481 accaaaatat aaatattgat tatatattgt ttctaatgtt gaagatggta gcgaagaaac
      541 tctcattttt tgctggagta taggatcaac tagactattt aagtgatttt gtaattcttc
      601 attgttgttt cctagaactg caagggaacg taaacggtag taatattcta tttctgttag
      661 tacttgttgt ttcggtttaa aatcatttat tgatatttgt aaattttgaa ttgtctcgtc
      721 tgaaaaatca tgttgtaatt ctggatgggt agctataaaa gtaagtaaaa agaacccttt
      781 tgtatacgtg atctgttgat tttcaccaag tgatttatta atttcctctc ttgattcagc
      841 tgtgaaccta tactttgcaa tttctttttt tagaatattt aaatagaatt ctttattatc
      901 aaaaattagg gcattaagta gtctgaaagt actttcccta tctctatctg cttcctcatt
      961 tccataagat aattgaaaaa caaacttaaa ggctgtctta cataggtttt ctttggcttt
     1021 ttcgcttagt ttatttagat agctattttt tagtgcagag tgaaattctt caggtgtaac
     1081 agacatagca tgtatgcgac ttgcatattg tataatttcg atcgttactt tttttcctaa
     1141 tattggattt tttaggaata taatttcata ggacttccgt ataacatcct gacaagtttc
     1201 ttttgttata tctcttaatt cccaagtatt accgttgtaa gtgactacag gatgagctga
     1261 ataatttctt tgatccttaa tatattttaa atcctcatat tcatagctat caattagctc
     1321 agttgaacta taagcttttt ctagtagttc catttcccat tttggagagt ttggatcact
     1381 ttttcttagt ctagctatat cttctaaaat tttcttagaa gtattatcct cgtaaatatt
     1441 tgctaaatca gataatttat caattaaatc taaaataagc gcactgtaat tgacagctat
     1501 tgcagaacga taatttccct gataaaaact acttctaact tcttctaata atggaataat
     1561 tctaggattt ttaacttttt ttatttcatc atctaatata aacatataaa tctccttttt
     1621 ttatttgtat gacaagttta ccataaaaaa aaattaaaaa gcgagacata tttatgttgt
     1681 tgtgttatca taataacata aatatgtaga gtgagatgat gaaaaaatgg atttgaaaca
     1741 atcgttttac atctggttat atcctgataa tcctatgtca ataatggctg atatttttgt
     1801 agttagcatc ttattgtatt tattttatct aattttcttt cacaatttaa tcgggtacat
     1861 gattcttgat tggaaaggaa tgttcgatat agaaagaaaa ccatttgcta acaatcaaac
     1921 ctataccgtc ttcgaaagtg gagattggga agaaaatgaa gttgatgtga tccatgaaat
     1981 tggattagct ttatcaggaa tacaagatgc tgatgttttg gtatcaatga caacggatac
     2041 tggatacaac gcttatgagg tattttatct tatgtatttt atatggcgtg atggtcaaga
     2101 aattatcaat ggtcgtgctg aaaaaacaat caattctaat actgaaattt ctttttgtat
     2161 gggtgaaggg gaaatgattg tatataaaga tgggtcagca aacattaaaa cagcctttgg
     2221 tgatattgaa acaagtatta aggaacttag ggaatatgtg cagaacccat ataattttca
     2281 atatttagca ggaagaataa atttagttta ggagtaaaaa tatgaaaaaa attataaatc
     2341 aaccaacaaa tcacttgata attgaaggtg ttattttcgt aacaatgtat tttactgtag
     2401 gaaatggcat ctcaaataca atcattcaaa aaaatccaca atacctatta tttagtcttt
     2461 atgcttggat tgtacaaatg gtttgggttt ccatattgat gctgttgttt tattggatag
     2521 tacgggttat tcttttattg ttaaacaaaa gaaaaaagga taggtgaata aaatgaaatc
     2581 aactaaattg aaggttgtat tgttatcgac agcagcatta ataaccctta cagcatgtgg
     2641 tacaactaat agtgctaata ataacaaaga cacaaagtct agtagtacga tggttactaa
     2701 aaacagcact acatcggcat caacaacaat gtcttcaatg actgaaaata atgctgaaaa
     2761 gtatcaaaaa tacgaagaca ttaataaagg tcaaaagccg gatgaagttt ataacaactt
     2821 tattaataca gtaaaaaatg atgaaaatta tgggaatgat ccattgcaaa ataaaaatct
     2881 gactatcgtt ctttacaaac ctgattgtcc agattgtcaa aaagcagaat caaaaatcat
     2941 gcaagaaata aaagaaggat ttagttatgc tccaacatta atgcatgata ttaccataaa
     3001 taaaccagct tacgagtatt acgcagttgc tgtagatatt actgatggtg tacctgagtg
     3061 ggtacaaaac attcctggtc tggctgatga gaacaatcaa tatcatacgc caacagttgc
     3121 agtagtaaca ccaaagaaag ttaacggcac actatactgg gatgtaatgg gaatgacaac
     3181 aaatacaact gatgaaatga ttgaaagtac aactaaatat tatatggatt tgggagcata
     3241 taaattatat caacaatcag agcctgttat ggacgatcaa tccaaagtta aatagatctt
     3301 tagggcgtaa gccctatttt tttaaaatta agtgataaca aataaatgat ttctgaaaca
     3361 aacgttctta ctcaactact cgaaacacac aagctaatta actagattat aaaggagaat
     3421 gcgtaatgaa agaaatcagt gcaaatgaag ctcatattcc gcaaaagaat caggttggta
     3481 tatataaggt gcttcatggt gaaggaattt ataaaataca gttacttacc ggttacaata
     3541 atggtgcaaa tgggaagtgg ttaaaggcaa caagtattcg tgaacttaga agtgaagtag
     3601 aaaaaattag gcttggtctc acaagtgaag aaatagctaa actgaaggga aataattctt
     3661 ttgtaattga aaaagaaaag gaaaaacatc tactttatcg tgagctgaaa attgaagaat
     3721 actatgaaat tgatttacct gaaaaattaa gaattattga tcaacgttca gaagaaaaat
     3781 ggaaaactga aatatatcca agcttaaatg actacaagac atcaggaaag cccatgtata
     3841 actacacagg ctttttaacc tacacacaat acaaatatgc ctttcgcaaa ttaaaaggca
     3901 ttaaacaagc tgaaattgcc ctgtatgaga tgaaaaaagt ggatagattg aaattgattc
     3961 aagatttagt gcaaaataca tggaatcaag cgattgtcga gctagaaaaa gaaaatggga
     4021 aaattttaac taataaatat ctgatcgtaa atgaaattga agaattaatt ggtttatttt
     4081 catgtgaaaa aggtgaagtc ttcttgaagt catcaccaac ctattcaatt ttggacagtc
     4141 cgtatcagtt tatacaggca aggagatgag ttagatgtct agcttgaaag atgactatat
     4201 ccaagcaaaa caagagtatg aaaaaataca gatgttgaaa tctgagaaag tcgaattatt
     4261 tttaacacaa aaattagcag aggatcatat tgctaactta gatgctaaaa ctttagagga
     4321 atatgatcgg cagtttaatc agatacatca caatatcatt ttgcttgttg agcaggcaaa
     4381 gcgaaggttt gaaaaagcgg aatatgatct attagatcaa ggaattgtat gcttggataa
     4441 gggattgcga agatattatg gtgcagagtt aaaaaagcaa aatgtagata gaaatgcact
     4501 aaaacatgaa atcttagaat tgataatgca acgaatttga agggatagaa agcaaatgtc
     4561 acaaaacatt agtgctgtaa aacaattaat agaagaagat ttagagacca cagttcagag
     4621 attagcggaa cgaatccatt ttgcaaatta tcaaaccatc tctaactggt caagcaggaa
     4681 cagaaatccg gaagaaattc caatgaaatt tttttatcga atcggaaaag aatatggtgt
     4741 tgatccgata aaaattttcg agaagaccat gatttattac tatcatggaa cacctaacga
     4801 agtgttagaa catcttttgg aagaggcaaa agaaaaatca tcaatattag agctatcgca
     4861 aaatgacaaa gttattcaag tgaaatgcgt tgatccaaca ggaaagatta ttgtcggttt
     4921 tgatattgaa agaaaatcca aaatagattt tattacacaa ttaaaaaaga taaataattt
     4981 agatattcta acgcttagac cagatcatga acagttgttt atgagtttta aaaaacaatt
     5041 gaaagaaata caaaaaagat ataacaaggt gtttcctaat gcgtgaaaag ctcaaagaaa
     5101 tcagagtttt ttggataatt aacaaagaat gtatcatctt atatactctt ggatttctta
     5161 gcatgatctt gttttggtgg ttatatttaa aacagtaatt ggagagggtc aagaggattt
     5221 ttatcaagat aaggatgtgg aaactgcatg tggaataata gattaaaaac aggattgtta
     5281 ttaatagtta tttcctgcgc tatgatgatt ggtatgagga tacaaaggga acaatcctat
     5341 tttgaagttt ctgctaacaa cgtaatagaa aaatgctatt acggtcaaca ttattggagt
     5401 gaggaagtca gagaaaatat agatcgtgaa tatgttcaaa gaattgtttg ggatgcatat
     5461 tctatcaaag attatcctaa aagtttaacg agtagattat tttacagtga aaaagataat
     5521 caaaaactct cagatttgat gatgaaaaaa gtatgactat tattacgaaa gagaaacaga
     5581 gtgctatatt cgaggggaaa aagcctacaa caaaagtgac tattggggtg acaaggcgaa
     5641 gcgattaact gcaaatttta gagtgtatga atcagagttt ataaacttga cctttcttaa
     5701 tagtgttttt attgattatg taattactac gaaacgcatt ggaagttatt caagtaccta
     5761 cgcatcctta gttccaatgt taaactcgat gagccgtttc ttaaaagaaa gagaaaagaa
     5821 agagctacag tatatcaaag aaatcatgcc ggattttgaa atgcacgaat ggcaaattgc
     5881 tttatcagat tggaaattgg cgaataaggt tcgtagaata acaccttttc aagccaagcg
     5941 ctttttgaga gctatgaaat ttgtgcaata aaaaaagcca ccagacaagt tgatggagac
     6001 taacacaatt accaacagtt gtaattgtgt tagcttacaa attaattatg gtgtttagtc
     6061 aatcccaaat tgtgaaatgg caccaataat tggaaaggaa aaatgaaatg tctgaagatt
     6121 tacgagagct gaagttacga aagaagcagt atgatcagta tttttccggt ttgttgaata
     6181 aacatattga agaaggactt gatcatgatt ttggaaaaga tgaatattgt ttatattgcg
     6241 aacgttacaa tgaaaaaatg tctgaatatc tacagctgaa aaaagagata cagaaattag
     6301 agaaaaaagt acatgcttgg aagtataaag attccatgtc tggttatgtt gaatctcaaa
     6361 ataagccaag aaaaaagaag caagcgtatg ttctaaagat ggtaaatggg gaagagttaa
     6421 ttgtattagc gtacagtgaa gaagaggttc gagaactcgt tgaaacacct gtcaggaaaa
     6481 aggttgaaac aataaatgag atagacgaca gccaatacaa tagcatctat attgaaacaa
     6541 gtcatggtgg atataagaaa ttagcaactt tccttagaag ttctaaagtt gggataattt
     6601 ctaaaaaaga cataagtgct gttaccgata gtttttgtac tttatctgtt cctaaagctt
     6661 atttccaata cgatagtaaa agatttgaac gcttagagaa attctgtaga ccgtatactg
     6721 tattgaaaac taaaaaattt aataaaacta aaagagtttc tatacagtta ccgactggtc
     6781 aaatctcatt aggtgaaaaa gactatctga taaaagtagg aaaagagtta attataaaag
     6841 taccggaaca cttatttaaa gaaaattttg agatacgtga aaccttggta tggaaagaag
     6901 aaaaatagtt tggaagacat agaatggtat aaggggaaat tgaaatggca gtaaataaaa
     6961 tattgcaggt actaatcata gacgaatttg gcggaggaga atggtttgat gtgcagtcca
     7021 tagactttga agaagaagtc gtagttatag aaaatattta cggcgaagta tattcatatt
     7081 cgcttgaagg tgagaatatt gaggatttac ggttgattgg tgagtagaaa aaaacagaaa
     7141 tatcaaaatg gagataaaaa ttaatagcat gtaaagatag tcatgcttgg gttaaaaatg
     7201 ttaaaattca aaaaaatgag tcagaaggga taaaagtatg aaaagagagg aatacaaaca
     7261 aagattaaac gaactgcttg aagaggacga aacattaact catggttcgc ctgatgaaat
     7321 tctatacatg attgataata tggtgatctt tggtggatat gaacttggta ataggtcagt
     7381 tgatcataat attttagaat ttgatgatgt atcatgggaa gaaattcttg attggggaat
     7441 tttggcggta cctgaaacta aaacctatat tagtgacact atggttcctt tttttgagga
     7501 attggattat aaaagacttc ccaaaaatga aaatcatata ctgggaggaa actaacaatg
     7561 ttaagtgact tatttatttt actgatctat ctaggtgtaa gtgaaattat tgcgtatttt
     7621 ttgtttgtca ttgctaatta tggtatttcc agtgcaatcg ttcaaatgtt tagattacca
     7681 gtaagtgaac taaaaaaatg atgagattat cagcatatct tttaatgttt ttgaatgtgg
     7741 tcacgttaat ctttgtagta atcggtgtga ctttcgattt aatggaatag tgggaaatct
     7801 ataatggaaa aaagagacac gaatgaacat attttttgaa tcaatattgt tgatggtttt
     7861 tgcgatcagc gcttaccaga aatctaaaaa agagtaatga ttgtttaatc atcactcttt
     7921 ttttgtaggg aaattgaaat atgtggagct tgtattggtt tagttaggat tgcttggcta
     7981 taaggagcta gttctttatc aaaaccatca aagtaggttt tcagtagcga tttaactgat
     8041 cgctcatctt gtttgatttg gataatttca gcatccaaat cggttgtgag atcaggagct
     8101 tttgatgcga ttacctgatt ttttttatct tccaactctc ttaggctgtt taacaagttg
     8161 taaaaagaat cattttgatt gttcattcca acgtgagttg caattttaac agaagtttcg
     8221 tccgtattgt catcaaaaga actcattgga atatcaagta gtaacgagga tgtttctttt
     8281 actgactttt tctttacagc attttttgtt tttccatctt ttttgctctt tactcgagat
     8341 gtttttggag ctagtttagg taaatcactt gttttatcag tcatttatta gcttttcctt
     8401 tctattaatt tatgttatta tattatcata ataacataaa aaagtacact ttttgggggc
     8461 gtagttattg aaaaaatcta agagaaagat tgccacattg cttatgttaa tggtgcaatt
     8521 tacagggatt gcaatgagtg taatcacaat aaatccgcaa gtgatacatg ctgatgggat
     8581 agctacttat gatgcacaat ttaactgtac tactgaaggt agtgggtcag gaacagatag
     8641 cgatggaaac gatactggaa gtggcgctgt aacaggtgat gtagccaaaa atattgaaga
     8701 tatttacaaa tacatgaatg gagaatatgg cttatcaggt gctagtattg caggtatttt
     8761 aggtaactgg aaacaagaat caggtattga tcctcgagca gtagaagggt attacggaga
     8821 tggacagaga gaagttgact tcatcaaaca atttactgat ggtctgatgg gtattggcta
     8881 tggtcaatgg acagctgggc gacatacagc attagttgat tggtctaaga aaaataatgg
     8941 cggttcttgg tggactacag aagcccaatt ggactttatg ttcaaaggtg atgggggatt
     9001 cgtaggaata ttaaaagatt atgctttaaa tgcttctgat gatgtcgtag aaaatgcagt
     9061 aacttttcat aaaaactggg aaatttcagc tgattccgaa tcagctgtaa tagctgtacg
     9121 tggtgaaaat gcaaaagaaa tctggaagta catgaaaagc aagggtatgg acggtgcaaa
     9181 agatgaaagt aagatcaata aaatatccgg aggttcaagt accggagatg gatcgaataa
     9241 ttcatcaagt tcagcatcag gaacagtaga agatgcctgt gcaactacgg atgacgctaa
     9301 ttctggttct ggatcaattg ggaaagaagg aaaaattaac ggtaaaaaag gtcaagtaat
     9361 agcgaatatg acttatgaag aagctttgaa aaaatatggg aaagcgatca cgctaccaaa
     9421 attcaaagaa ccagattggt caacttcacc ttttaacgga atatatcaag gtcagtgtac
     9481 agagttgacg tgggcttata tgagccaatt atacgatggg aatcaaccga ctactggaaa
     9541 tggtggttat gtatgggaaa gctacaaatc ggcaggagca aaaataacga acaaaccaat
     9601 cgtaggttat gggtttagtg cttcggatgg atggttatgg gctgttggag atgcagggca
     9661 tactggtgta gttatagcgg tgtttgaaga tggatcattt ctatgtgcta actttaatgt
     9721 tccaccaacc caagctccaa caaggggagt ttcggtaacg ttgattgatg gagtggacgg
     9781 atcagataat gtgcatttct ttagcggtgt aggaaaagct aaatttgaaa tcgaaaaata
     9841 aattggaatg aaggacgata tagatgaata gtaaagtgaa agatacaatt atcatttctt
     9901 tgctttctgg tatgttatta gcactgcttg ttggaatcct attcttcaat aagcagaatc
     9961 aggacataga agctgaaaaa cacagtgtgc atattgaaga taagctgaca ttctttaaag
    10021 aggttaaacc aaatgaggtg gatggattac ggaaagattt agaaaatgat attcaagaaa
    10081 tgttgaatgg atcagttcaa aataagtttg cagatcaatc aggtgaagaa tttttgagaa
    10141 aactatttat tgtaacaggt aaaccaccaa ttactgataa gagtagtgag aaagaaaaaa
    10201 tcgagtacta taagcctttt acttttaagc taacaaactt tggaattaag acatctagta
    10261 gtgggttgta tgaagcattg accgattttg aagttcaata caatggaaaa aaagtgtatg
    10321 ataccacatt aaccatcaca ctaaataatg ataagaaagt gactgggggt gctttttatg
    10381 caaaatcatg aaatcactac tgctaaaaag gcgatcggaa tactttccat aattgtgatc
    10441 ctttgttgtg tggtactatt tcaaaagaaa aatgcttatg ataataatgt caaagaattg
    10501 gaagacctta aaagtaaaca aatcgaagta gtcaagaata accagaaagt gaaagctatg
    10561 caggaagctc aatacaaaga attgggaaat gctgaaatta aggaacaaag taggaaattc
    10621 tttaatttat tttacaactg gaattcatgg gaaaaatata cgaagaatat gaaggaaata
    10681 caaaaagaat ttcctcagat agtaaagtct agtcctgttg atatttctgg cacgatggta
    10741 ggcactggta atagtccaat atctagctat actgctgatt actatacaac aaatcaaaaa
    10801 ggtaaaatgg ttgaattgat tacacagaca agaaatactc caacaacagc aacaacaaca
    10861 atttggcgtg gagtaacaag cataggagaa aatcaattgt tttatttgga ggatttagat
    10921 agctatgtaa gagcagagta aaataaaaaa agagctaacg gtaccaacgt tagctctttg
    10981 tgctgacgat gataacaaaa cctaccgaaa aaggattgtt tcatcacaaa cacaaacaga
    11041 aaagaattga taaaaaaccc gaacctcaga atttttatta atcaattcat ttagattata
    11101 ataaattgag ctgaacatta caatacgtat atgttgtaaa acgtaaaaaa agtcaaaagt
    11161 aaatactttc ttaaaaagtc aaataaaact attaaagaca atatatatgg tttatttgac
    11221 ataagaaaat ggtctagatg ataattgtaa tatagaattg tagacttaaa taaagcataa
    11281 aatacctttt atgataaggt atagctctta attttaagca gttttagata taagattgaa
    11341 agtaaagtgg gggagaataa taatggcaga tcataaatta gaaaagttat tagaagaaac
    11401 gtggaatcca aaagaattta gtgaattttt tatggagaat tttgaaactg acttagcagt
    11461 gattgttaaa gatgctctta gagagcaagg gtatcctgaa actgcaaact atataaacat
    11521 taattttact ttgtatactg aaaataaagg aacttgggat ttttgggcta ctttagcaaa
    11581 taaggagtta agtgataaat cagacacagg aattcgtaac ttttttgaat caaacagaga
    11641 tgattatatg tatgctaaca atcaaaataa attgaacttt agagtagagt ttgatgaaac
    11701 acctgaagaa tttatagaaa gacaaccgcc taaagaaaat gtagcaaagg tattggaaga
    11761 tcgttggaat tcagatgaaa tagtttcaac aattagcgaa ctaggcggac aatatgaacc
    11821 gctagtagaa gcggttagag aagagctaag actgaataag tttcctgatg ttcaaaatat
    11881 tgatgtttct caaattgaaa taaacgtcaa gatcacgaat aaacttgatt atggtagttg
    11941 ggcagatata gcattagaaa aatacatcta ctcaacgtta aaagagttta tcgaaaatag
    12001 aatggatatc atgtatctac agcatccaca gtatttaaac tttggtgttg aaatagctac
    12061 acctcttgaa gaatggaaaa tggagcaagg gcttgactag cctttgctcc atttttttat
    12121 tttacaaatg aatacagttc gtcgttttta ccaagaatga ttgtttgccc aactttgaga
    12181 ttgtcaggtg atccttcagc ggtttgtaag gagaacgttc cattgaactt atcggatacc
    12241 gttataggta gctttaattc tgatccttcc tcatctttga gaattgctgt ttttcgttca
    12301 tcaaaataaa cagtctttat taaataattt ttcgtagtga tctcagcaga tttgtctttt
    12361 tttgtagtag taccagtttc tttagaatta gaggtatttt ctacgactat tccatctttg
    12421 gcatttgagc ttgtgtttat ttgattgaat attttcagcg acaagataac gctaagaata
    12481 gtcaatatag aaacaagtgt aattaatact gataatttcc tttttttgtt cattttttct
    12541 taacatcctt ttttgttttg attagttaga tattccttat ctaacaagcc tttttaggct
    12601 attaaatgaa gataaacccc aaaaaaatat tgcaattatg acagtgcaat ggtactatta
    12661 ttatacaata aattttgcga aaggggtagg tctaaatcgc aaacaaaaag aaattgaacc
    12721 tagacaaata caacttgtat accgcaaggg aagcaagttt gattttgggt aaaggtagaa
    12781 attatgttac aaacataatc aactattatc caaatcgttt gcctaaaggt tcgttcaaga
    12841 aagtgggtga caaaacctat attataacgg aagaaggaat agaagcattg cgatcacaaa
    12901 cagaaaataa aaacaaaaag aaggaatgaa tatgaagaga aattcgcttg gtatggtttt
    12961 attggcatca gctgtacttg cggggttatc agtaccagta acctcacatg ctgatgaatg
    13021 gactgcaaac acaccggatc aaatccaaat tacaacagga caatcaagtt atgcgttcaa
    13081 aaaaggagat actatttggt caactgtaga gaagcttaaa agcttaggtt acaagactac
    13141 tgttgctgag tttgccgaat tgaacaatgt tgatttggca aaaggagaac aacggactat
    13201 cccgattgga cgaactttca acatcagtaa agatacatta acagttaagg aagcagatgg
    13261 cgaagtagtt agtcaaactg ttcaaaaaga taaacctgat cctattgaaa atacggagca
    13321 agagaacaaa aaatccgaga ctacaaaaga atcggaacca acagcaaaca cttctgataa
    13381 gacagaaaca agtgcttcaa gtgttgatgg agcaagttca tctaatacaa ataattctac
    13441 aagtgagaaa gaagcatcac agggaacaag tgaaagtagc actacggaag ctgatactgg
    13501 aacatcaaca aataactcac aatcaacatc aaatgatgca aatgaatcaa ccagtacatc
    13561 ttctagtgat caatcacaaa caggttcgag tgatgaaact gacagttcta cttcaccaag
    13621 taaacccgaa caaccaacta atgttgtgct aggcgttcca tttattagtc aaggtaacac
    13681 aatgctttgc gaaggaacat ctttgctaga agcgttacat tataaaggtg ttgcaacaaa
    13741 tcaagattta atgacttttg ttaaatcaat gccactatct cctgacaata atccaaataa
    13801 tggtttttct ggtgaatgga gacacaatgt ggatggaact tatcaaggta tgaatccggc
    13861 tcctgtagtt tcatggggtg ttgctaatgg cggaaatgtt gtagatattt ctggttcatc
    13921 ggtacaagga ttaaaagatg agattgtaaa tggaaatcct gtagtagcgt gggtaactta
    13981 tgcctttgaa cctgctcaac ataaaccaat gttttggggc gatgctattt ggaatcgaca
    14041 tgtagtagcc gttgatggat ttaaagacgg tttttaccat gttgtcgatc ctgtgtttgg
    14101 ggcaagttgg attaatgcag gatcatttga aacagcatat aacgtatctc aattagcggt
    14161 ttcggtacgt taataaaaga tatcgtttat atactaagta gttatatagt ctttatttgt
    14221 ccttgcttaa ctacttagaa aacttgttgc tcatggtggg tagaactaaa aggggtgatg
    14281 ctatgaatac tagagcgttg aaacagcttg ctttcaacga aaaaaatgat taataggtgt
    14341 ggtgatttta acttaggaat gggcgcgaag gtcattacca caccgacata tcgtggctca
    14401 ttttcttcgc ctaactggta taaagaagga gtaacgagag atgaagcatg aaaaaacgat
    14461 aattttaaaa tcaaaaataa tttattgttt tgcgacttta gtaatgatgt tatctacgct
    14521 tataatgcct ttttcagcaa taagagctga agcagatgtc acaaaaccga caagtgcaaa
    14581 atttatagaa actggcgtaa aaacagacgg ttatattagg gttaatatgc cgaatcatcc
    14641 aaatgaatgg atgatttcaa gtcaatttaa agattctcat ggaaatattg gatattgtat
    14701 ggattcagaa ttgccatccc caacaggaag tggagccgga agcttgaagt acaagggagc
    14761 tggcagtgat gagttctatc gtatgtttaa aggtggtttt ccatcaaaaa cagcaaagga
    14821 actgggtgca ggaaatgata cagaagcatg gtatgcaaca caattagttt catgggtttt
    14881 agccggaaac tttaaagttt cacagattgt atggtcacat ccaaaccata ccgccgcaga
    14941 aacagctcgt gtaaaaaaag catttgaaaa aatttatgac tatgctaaga atggaaaaga
    15001 tacgcccaac actgagtttt ctatcacagc ttctaagaca gctgacgaag gaaaatatca
    15061 cactttcaca tataaaacag catcaaataa gactggtaat gcgaagctca cttttacatc
    15121 agcaaaacca gctggtatga agatttatga tgcagatggt aaagaaatta ctaacaacac
    15181 tgtgaaatta aattcaagtt ttactattaa agtacctgtg actacaccaa gtggtacttt
    15241 gtcatttaaa ggtactgcta atgttagcac aaccaatcct tttacttttg atggacgagg
    15301 tgtgtatcaa gatgccgtag ttatgatcac tacttcagaa acaaaggact ctaaatcttt
    15361 gagtgctaaa tggacaagag ctgttggtca ggtaacagtt aagaaagttg atcaagatgg
    15421 aaatgcttta aaaggagcgg agtttactct aactgacaat aacaatgcta aatctgttaa
    15481 gacaaccgga gatgatgggt tagctacgtt tgatttgcaa caaggcttaa catacagctt
    15541 agaagaaaca aaagttcctg aaggttatca aggttcattt aaaaaggatg gtattactgt
    15601 taataccgat ggacaagaat ttagttacac tgctacgaac acaattaaaa aaggtaaagt
    15661 aaaagttaaa aaggttgacc aagatggaaa accattagct aatgctgaat ttaccttgac
    15721 ggatgattca tcccaaacac aagcagaaaa aacagatgaa aacggacttg caagcttcga
    15781 tattgtagca aacaagacct acagccttga agagaccgga gtaccaactg gttatacagg
    15841 cgtattcaag caagaaggaa ttaccgttaa agatgatgga caaacttttg aatatacagc
    15901 tacaaacact ttgaaaaaag gtttagtaaa agttcataaa gtcgatcaag atggaaaacc
    15961 tttggcaaat gcagagttca ctttaaccga tgaaaaaggt gcaacacaag tagaaaaaac
    16021 agatgaaaat ggacttgcaa gcttcaatat tgtagcaaac aagacgtata gcctagaaga
    16081 aaccggagta ccagtaggtt acacaggtgc atttaagcaa gagggtatca ccgttaaaga
    16141 cgatgggcaa acttttgaat atacagctac aaataatttg aaaaaaggtg tagtaaaagt
    16201 tcataaagtc gatcaagatg gaaaaccttt agcagatgca gaattcacct taacggatga
    16261 aaaaggtgta aaagaagtta aaaagacgga tgcaactggt ctggctacgt tcaacattat
    16321 tgcgaacaaa acttacaact tagaagaaac aaaagtacca acaggttaca caggcgcatt
    16381 caaacaagaa ggaattaccg tcaaagatga tggacaagtc tttgaatata cagctaaaaa
    16441 cactttgaaa aaaggtgtga tcaaagttca taaagtcgat gatcaaggga aagcattagc
    16501 aaacgcagaa ttcactttga cggacgacaa aggtgtaaaa gttgtacaaa aaacggacag
    16561 aaatggcttg gcaacattta atattgttgc caacaaaacg tacaaaatcg aagaaacaca
    16621 aaaccctaat ggttatacag ggaaatggtc taaagaaggc atcaccgttg ctgacgatgg
    16681 acaaaccttt gaatatacag taattaatca ccttgtacct gaaacagtaa gaacaggcgg
    16741 aatcggtaca tcagccttcc ttcttgtatt tctaattgca ggattgagta tggtgctact
    16801 gtattatcga gaacagcaca aagcaaaata aaaaagtgtt aatggaaaag aagtaaatat
    16861 gaaaaaagaa ggctgacgta tgaaatcaaa aaaaattttt tcaaatttaa tgctatttgg
    16921 tactttgcta ggagtgggat tgggcgcaag ctcaatctct tctagccttg gactaggggg
    16981 gcaagtagca tatgcacaac aaaactataa ttatcaagga actggaacga ttcatatcca
    17041 taaagtaaca aatactaatg gggatgggaa ccctgtctca gatattgata acaaagggaa
    17101 agaaatagct ttaccaaatg gtgtaaaacc tcttgaaggc gttgagttct cttatgtgaa
    17161 acttactaaa gatgaagcta aatccttggg atggacggat agtgatacta caaaaggtca
    17221 acatattgat gatgctaaag cacgattatt actaaacaaa aaatacagtg aagtaagtag
    17281 aatgaagact gattcacaag ggaatataga catacctata caagtaaata cagacgattt
    17341 aacagataac ttgtatttga ttgttgaaac aggaacagtc aaaggtgtag ttgaagaagc
    17401 gtatcctatg attgttaacg tacctgaact aaacggatca gatgatcaat actttaatta
    17461 tgatgtacat gtctatccta aaaactattt ccaattaaac tcagcagagc ttgataaaaa
    17521 agacgaagat ggaaaggctc ttgccggaac tgtttttgaa ttgcgaaaag atgatggatc
    17581 tgatcaggtt gttggaactt ataaaacaga cagcacaggt aaattaactg tggatggttt
    17641 ggaattaggt gactattatt tcctagaaac cgatttggga acagatgcta atagaacaac
    17701 ctatttacta gatggtaaaa aattcaaatt tagcgttaaa cgtggggaga ctgctaaagt
    17761 agttcttgat gttaccaact acaaacgacc tgtaattact aaggtaattg ataaagaaac
    17821 cgttgatact ggcgaagatg ttcaatatac attgaaacca tcaattcctg gtaatattgg
    17881 taattacgaa aaatatgttg tcaaagatgt tctaggtgca gagttaactt atgattcatc
    17941 agaagtgatc gaaggaatga ctttagatac tgattacagt atcgaacgtg acggacaaac
    18001 gacaaactat gtctttactg aatcaggtat ggataagctt cagaaacaat ttgatgcagg
    18061 ggatcgcttc tttacaattt tgatgaacgc tcatactaat agtaaagcta aaatggatac
    18121 accacttaag aatgatgttt caacgatcta caacaatgga tatgaacccg aagacgaaac
    18181 accagttgat cacgcttata caatcattgg tgatcaccaa ttcattaaaa cagacggaga
    18241 tacaagcaaa gcattgagtg gagcaaaatt tgtagtgaag aacaaaattg atccgaataa
    18301 agttacttac ctaaaacaag atccaacaac gaaagctgtt acttggattg cagataaatc
    18361 taaagctact gaattcgttt ccggatcaga cggtaagttc caaattgaag gtttgcaata
    18421 tacctatgat gtagattttg ataaacaagg taatccaaca atcacagata aaaaaatcaa
    18481 tgattatgct cttgaagaag ttgttgctcc ttcaggatat acaccaacta gaaacgatgt
    18541 tccatttgtg gtatcgaatg atgatgcttc tagcgaagta acagacatca agaaccttaa
    18601 aacacctgaa acagttcgta caggtggaat tggaacagta gtatttctag tggttgcagg
    18661 tgtggcagga acagggctat atgttgtcta caaacgagaa caacacaaag cttaatgaaa
    18721 taaaattccc tagagtgttt ttggctctag ggtttctttt taaaaagtgt gtgaaaagta
    18781 ggtatgagca tgaaaaagaa gaatatcaag ttgatcatct taaaaattgg gatgttgcta
    18841 tgtttaggag taggtctata tcctgtaatt actcaggctt atacctacta ccaaactcaa
    18901 caaacactaa actcctataa ggaaaaatat gatgaagctt ctgaaaagga gaatgaagaa
    18961 gtcttcaaga gatattcaga agttaatagg aaacgaaaag acacagaaca aacctcagtc
    19021 acgattcctg aagataataa caatattccg tcaaatggaa atcttcagaa ggataaatta
    19081 ggtgaattag tgggtgaaat tcttatacca aagattaatg tggatttgcc aatttatgat
    19141 ggtgtaaacg atttccaact atcagcagga gcaggaatat taaccggaac tgattatcca
    19201 actggtggga ttggaaacca ttctgttata tcagctcatt caggcattcc taataaaaaa
    19261 tattttacag atttagagtt gctcaaactt ggtgataaat tttttattga tatttcaggg
    19321 aaaaaacttg cttatcaagt agatcggata aaaacaattc taccaaccga atttgaggat
    19381 ttgcttcctg tggcaggaaa agattatgta acacttatga catgtacacc tgttggagat
    19441 aattctcata ggttactcgt tagaggggtt agcatacctt accaaaaaag tattgttgag
    19501 aaagaaaaga agaaagaaga tttaaaggta aaggcgcaga tgaactggta tcctatcgta
    19561 gttgtagggg ttttattaat aatagctgtg atagtcatta ttaaaaaaat agtagcaaag
    19621 agacgaggaa tgaaaaatga agaataaaat actacttttt ttgactctta tttgcacttt
    19681 ggttttaaca atttatcctg caaatcagct ctatcatcaa ttcaaaacaa aagagaatgt
    19741 ggcggaaatc caagagaaaa ttgagaaaaa acaaactcct tcaaaagagg aagtggcaaa
    19801 aaaagtcgaa caaataaaat cgaacagcgg taaccaagga ttagacaata ctcagaaaac
    19861 agataaagga gtagacaata ctcaggaaac agacggtgga tcatttgata ttcgtgaagc
    19921 tgaaggaaag gtcaatccat acacaggaga tgttttttca aaaaatcaaa cgaaagattt
    19981 tgaaccatct acctattcag gagcggttgg ttatgtctat attccaaaaa taaatgtgct
    20041 agagcttttg tttctaggcg cttcacagga gcatttatat agaggtgtgg cacaaatgag
    20101 tgctactagt ctacctttat caggtaaagg tcatcaaaca gtaatagcag gtcatcgtgg
    20161 cggttatacg tcaccacaat ttctttatgt tgatcaatta gtagccggag accacattta
    20221 tatagattat cttggtgaaa aagcagttta tacggttttc cgaacagacg ttattagaaa
    20281 ttacggtcag aattcaacac tgactgatat tcctgattta gatatgttaa cactttatac
    20341 ttgtcatcca tatcctcaga actacgatcg tttattagtt agaagtctaa gagatgaaaa
    20401 agcaaaatac atcacgccac aagtaacagt tggcaatacc gcatacgctg atgccattga
    20461 tagcgagtcc gtttcagata agacagaaac tgttacatct tctaatgatt tatttgagga
    20521 tgttgatcgt gccaacaagg aattagatgg aaataatgat cttaatattc cggaacaagg
    20581 tagcgtagag atgcaagaca gaacgtttgc tgaaaaggca agttcaatat ttacaggaat
    20641 taccaataaa catcagaaaa tgcttttagt catttggact gtaataggag cattagcaag
    20701 tctaaaggtt cttattcttt taatcaaaga gtttcgaaaa gcataatgaa gattataaaa
    20761 attgatagag tacagtaaaa agggattgat actattattg atctcttttt tattttgaat
    20821 agagctagat tcacttttaa ataaaatcaa aactgatctt aattctaaag aaaaagtcaa
    20881 gaaaaaaata caacaaattt ttttatcaga atatttatca gaatattatt agaaaagata
    20941 aactcaaaag cttaatttaa tagggttatt ggttgtattt agaaataatg tatggaaaag
    21001 ctataaatca atagataaga tgtagaaaat cttatttgtg aatgaaaaac aagtcatcgt
    21061 aaaatattaa taggaggtgt agtaatggtg ggaatatcaa aaacagcttt agactcatta
    21121 gctaaactat ttagtagcag gtttgatggt gcagaatttg ttgaatatct aagccaaaac
    21181 gaaagtggaa aaactctgat cgaaacaatg aaaaaagact atttgaatga aaatgacttt
    21241 ccgacatgga cgaatattga agatgctaca tgggatgtag tatgtacgat atattctcct
    21301 tgggtaacga ttgctgattt tgttttagat aaaattggag gggatacata ccctgatgcc
    21361 aaatctcttg ctacaagtga ctttaaaacg ttctatggtt atctaatagg tctaataggc
    21421 aatggaatag atttgaaagt tacgccaaaa caaacacctg aagaaattga aaaagaaaaa
    21481 ggagaggttc aaatggctta tgcaaatgac agagaaaaag taaaattatt ggaaggtaaa
    21541 ttatctgaag aagaacttgg aaaaatggtg caagaaatca atgaagacag caactatttt
    21601 cctgaattga aggtatatca aaatgacgaa gatttcttta atgaaatgtt tagtaatagt
    21661 ccatgggaag cagtgagtaa aacaaattta ggagaatgga actttcaaga tgatctagtt
    21721 gcatttagca atgatgggta tttacgatca tattcagaaa gtgagtatag agctgaatta
    21781 aaaacgtatg aaacggatat tctgatgagc tatttaaatc tattagagag tggtcaggga
    21841 gagttaagag ataaagttga agaactatta aaagaagagc tatagggatt atttcaacat
    21901 aaacacaagc agaaaactac taaacaaaac gtaccatgca aaaagtcggt taaaccggct
    21961 ttttgctcta ttatgagagg agatcaaacc atgagtgcaa caaccgatat ggctttagaa
    22021 gcagtaataa aagataatac aggaaatgtc gaaaacgtag aagactttag cgatattgca
    22081 atcaatcttt cagcatggat ttcagctgta ggagaagaaa atatcgaatt tgagatcaag
    22141 aatatggatg acttaaaagc aaaatttcct tttatcgcat cgaaactaag tcaagttgcc
    22201 gaggataaat cgtggaatga attagttagt ttttccgaaa aaatttatga tattacgcaa
    22261 gaagatgagt gtgtttcatg ggaaatgaat aatcaataca agaaaattga cgctttcgtc
    22321 aaatcacgta tagaaggaac agcttttgag tttgaaggta tagataccgc agataattgg
    22381 ttaaataaag aatcctttat taaaagtata gcggatgatc ttgaaaaaca atggtctaag
    22441 gaagactatg cagagtacct aaaaacagaa agagatacag aggtgaaaga aaaactcact
    22501 gaggtatgtt tggatgaaca tattgatccc aatatcgtaa aacaagaaga ctatgaagtg
    22561 gttattgata aagttcctac tgattttgag gaagttgtaa agtatctagt tgaagaagca
    22621 ttatcgcaat actcttcaga tgaggaagtg gacgaagaaa ctgttcgtac cagagtttgg
    22681 caactggttt ttgatgacaa agattataaa tatttgagtg atcaaaactc ggttaattgg
    22741 agtgtacgat tattaattga tcaaaatgat attgaataaa atagagctga aaagctctat
    22801 tttttttgtt aaaaaaacta gctattttat taaaaataat ttggttcaaa ttttattttt
    22861 ttaacttgat aatttcttgc catccttttt taaattggct atatatcaag gtttatagtg
    22921 ggaataaata aaaatacatt tgacaaaatt tacaatatag tttattatat atttatctta
    22981 ttatgataac acaataaaag gaatggtggt atgaaaaaga agaagtttag tcgatcgttg
    23041 ttaggaattt tggttttagt tgcggttggt cttagtggca agggttactt tcagaataac
    23101 agcactcagg aacatgattt tcagatcaaa agtagtgttc agataggtaa taaagcagac
    23161 agtgaatcaa aagaattttt agggatacgt tatgatccaa acaaatatcc aaataatatc
    23221 gtaaacatta atgatgggaa atatacactg acaaaagaag accatgaagc attatcagaa
    23281 aaaggcagtc aaaccttttg ggtaaattat gcagatttag atcaacttgg aagagcagga
    23341 gatgttgaag cgttgatcac ctatgatgct gtaaattctc actcatctaa aaatgtggaa
    23401 cgtccatctt tcaaaagttc tgtccatatt gcaggagaat acaaggatgg agtatttgat
    23461 caagagagag atacttgggt cggcaaagat tcaaacaatg aaatcactca gctagaaggc
    23521 tataaaggtt atctctataa caaaagtcat tcattagcat ggtcgctagg aggagatatg
    23581 gaggtacaca atttaacact tggaacgaga gcgcaaaatg ttgggaaaaa tgatcagaat
    23641 ggagggatgg cttactcaga aacgattgta cgtgatgcaa tctataaaaa taagaatgaa
    23701 aaagtattgt ataaagttga tccaatttat aaagggaatg aattagttcc tcgtggttct
    23761 catgtcgaag ctttctcagt taacgataat ggaaaaacgg taaaccttaa tgtttatgta
    23821 tttaacaatc aaaaaggaat caacatcaac tatcaaaatg gtacttgggt aagagattag
    23881 aaattgagaa ggtgaagaat tggaaacaat aagcatcaat ggattagata aatcagttgc
    23941 aaatcgaata aaaaaaggaa atggctacta tcttctgaag aagggtaaat attcagttgc
    24001 tagagagtta gaaacaatga gtatcgtgta tgtagctaag aatcattttg acgtagaaca
    24061 ggctattttt gatccagatt ctgaaatagg gaaatgtgtt gaattatcag agaaaactgt
    24121 tagtacaaaa ggggcgatgg tcattgagag agaaatgtta gacgaaatca gagtaatcat
    24181 tcctaaagat acgcagatgt gtgaggacag cataagtgac gatgaaccaa aatcagaaag
    24241 aaaataagga gatattcaga tgagcgaaaa atccattgaa ttaaaggaat ataagcgaag
    24301 cgatggagaa aaatattatc ctgtagccag tttttctaaa tcagtatatc tggttggacg
    24361 tgcattggta gttggtgcaa ttggcatata tattttgcat tgggtaacaa aggttgtaca
    24421 actgcttgta gataccttag taagtattct tgtctcgtta aatgatgtta acggaacaga
    24481 tgatttagga ttaaaagaga tgtttaaaga gttactcaat gcgttttttc ccaattattt
    24541 aagttattca tataatgtac aaagcttttt tgcaaagcta cacttggtag acatctctat
    24601 tttagtatta gaagcaggaa cggtattctt tgttggatat ttggttactt tgatgttcag
    24661 gcatcactat ggagaacaaa gaccattttt tgatgatatg gaaagtagaa ggttgaaaag
    24721 agaagctcta gaagctatgg atgtgaagta tgatccaaac aagattatag gagatgaaac
    24781 gaacaacaaa aaaagaaaac gaaacaaaac gcaattagaa tccgatgtgc tatcaacgct
    24841 taaaaatatc aaaatttctg ttcatacaag acgtgatcta agtgtcaatg aagatattcg
    24901 agaatatatc gtaaaaatcc cgcaaccaaa agggaagaaa gttagagaaa cagttttacg
    24961 acaaattcaa gatttagggt cgatcctgac aagagcaaca agcggacgag ccaaatttgg
    25021 tgaaaaagaa gatgaagttt caggcgatta tttcattttc cgagcatcag taaatattga
    25081 aagagaacgt aaggaaagag taagtaccaa aaacaaagaa acggaaagag caacatcttc
    25141 aatcgcagtt tcaaattcac aattttcttt tccaatcaat ctctttgccg ataattccaa
    25201 aaatatccaa aaccaaaccg aaaaagctag aaaatatgcc gaaactcaaa agcaatcttt
    25261 agaactttat ctatcttctg ctgacgtacc tgcaagtcta acagatatgc acgttgggaa
    25321 tacatctatt gaatatttgt ttactttatc tcgtaccaga aaaattcaac taagctcaat
    25381 gaaagaagaa attgaaactt acttgcatat atcaggtgta atcgtgcgga tcaacgcagg
    25441 gcgtattcaa attactttac cattaggaga aaatgatcgt attccaattg atgtaccatc
    25501 aatgatcaat agcgtgtttt agaagacatc acaaatagaa acagaaaata caaactacca
    25561 gttcacaaac agaaaagtac cgagaaaagt gaggaataga aatggctatg aaattattag
    25621 agaaagtcaa aaagagagcc gaaaaagctg aatctatttt gctagataaa gaacctaata
    25681 taaagcttaa tggaaaattc agtgtcaata tgttgaacac aaaggctaaa gacccaacag
    25741 atgctatttt tggaattaag cctgatggca caattgctca tttttgcatc agcgaaatgc
    25801 cacacatgtt ggttgcagga acgacaggat cagggaaatc agtattactg aatgaaattc
    25861 ttgttacagt aatgtgtcac tcaacgcctg atgaattaaa aataggaatt gtagacccaa
    25921 aaagggttga atttggaaga tacaaaaaat tgccgttcat gttggctgat ccaattacag
    25981 atatggatga agcttatgat ttttttgaat atcttgtgat cttgatgcat gaacgttaca
    26041 aactgatgga aaaagcaggg ttacaaaaca tcacgctata taacgaatat gccgaaaaaa
    26101 atggattaga tagatttccc tatgtgatct tattagttga tgaatattca cagttggttg
    26161 gaacacataa agaagtagaa ggtttgattg ttcaattagg acaaatggca agggcagcag
    26221 gtattcatgt tatcttagca acacaatctc ctcgatcaac agttgtcact ggtattatca
    26281 aagccaattt tccgtcacgt gtttgcctta tggtagcaag tgatttagaa agtaggattg
    26341 tattagatga aggcggtgga gaaagtctaa gtccaaaggg agatatgctt attaagcttg
    26401 ttgatggaag tatggttaga gcgcagggag cttacatcag taacaaagaa attgaaacaa
    26461 tcttcaatca ccttagaaat actatgccag aaccagaata tgttgattac cgagcaatcg
    26521 tagctgaaac tcgtggtgag ggcggtgaag acgaggattt tggtggaatt ggtaaagctc
    26581 ctgtaagaaa atctgctaaa agaaatttga acacaccttt agcaaatcca tcatctaaag
    26641 agccatcaat tgaaaagaag agtgcgtttg ctattaagct tgaaaaaaat aaagaagaaa
    26701 aagctaatca gggagctaag tcactagaaa aacttcagca agaaaaatta gaaaaactag
    26761 aaaaagcatt atcatcatca acttctgaaa ctcaatcttc aaagggtata gataatggac
    26821 aatcaattac aactaaaaac aagcctaaaa atagtaattc aaatctctcg gtaaatgttg
    26881 ttatcacaac tgataaatct gaaaaaaaac aagtgaacgg aactacttca cccatcatgc
    26941 aaaaaatgat aaaggcaaaa aaacaggtgc agaaatgatt atcattagtt cctttttgag
    27001 atggctaaca ccatataaat atacagatga aatagttgag aagcgagcga agaaaaaagt
    27061 taaaaaaacg atgttaactc ctaaagaaat gctagatcgt ggaatattgg gagtgaaggt
    27121 tttagaagta aaccaaccgt ttgaattgga taatgcgaga gataggttgc ttagagctga
    27181 agttgatgtc gcatactttt atcatgataa aagcaagcat caaatagcta tcaaattcaa
    27241 tccaaaatcg gcatggcgat accaagcaag agatgaccta aagcgtagga agctgaaacc
    27301 gatgctctat cctgaaggaa aagaggcatt tgatagaacc catattgttc ccattggatt
    27361 tcatggtaca gagtcagata accgcctatt ggtagggtgg aacagctcac aaaatagagt
    27421 tcagatcaat aaatttgaga agaaggtaag aaaatttaac gatcggaaaa taatactttg
    27481 gtttgccaat attcagaagc aaccagatgg gacagcaaag tgggaagcgg tcatatttga
    27541 tgaagatggc aaaaaagtaa tgtctgaagt atggcatgat aaagctaaat ttgtttggca
    27601 gtagaggtga aaattgtgtt aactaaccta aaactatata gagagggatt taacgaaaaa
    27661 gtaagtatcg gtgaatctat tgaatattta ggaaagaagt acattattat tcgtattctt
    27721 gaaattaaaa aactttattt tagtaaatat aataatttag cagttagagt tctcgtccaa
    27781 aaggttggaa atccaagtga ctatagaagt gattaccata actataaaac agaatcatct
    27841 gtaattaagc gttataatca atcaaaaaat gatgagagaa tattcaaagt aggagaaatt
    27901 attatttcta agtatgggat agcatacgaa atagtttcta ttaaaaaatt ttattatgaa
    27961 tttgttgatt tggttgtaga atattctgtt cgattgatcg ttccgtggag taaagaagaa
    28021 attaatgagg cattaaaaca tgaacgaaaa agtacattca aagttttaga aggtgaaaaa
    28081 aagtgaaaac agaccttact aggcaagctg agaagtgctt atggcatgaa acaaatcgca
    28141 tgggtgtatt tggttgtttc gaagtcacta tcggttggga tggcagtgaa agagtagatt
    28201 atataactta ttcagtagat aacacagttc gatgttatga gatcaaagtt actttagctg
    28261 atttaaaaag caaggcgaaa cagactttta tcggtgatta taactattta gttgttacta
    28321 gtgatttgtg ggagaaaatg caacaagacg ataaacttat gcggaaatat tactatcaag
    28381 gcgtatacgt gttcaatgaa aaatatccta gcataataag tgttaagaaa gcaaggaaac
    28441 aaaaagtatc gctaggtaca agatcaactg tattagaaag catggttcgt tctatgaatc
    28501 gtgaagttaa gaaactctat aaagtaaaac cattttggga gatagcagag gtggaaaaag
    28561 gatgattcaa acatttgcaa aaatgagtag aagtgcttgg attgaaaagc tggaaaatga
    28621 tttgagtgtt atgcgattag ctccaaagaa attcaaacga gagattgcag aaaaagaagc
    28681 aattttgtcg gtattgaatg cggtagaact ggacgaaccg aaaaagtcag ttgatgtacc
    28741 tgaaaatgta gcagagttac tagattatta tcgtaattcg tcagatgtcg atttgttagc
    28801 tctgatatta acatttcacg attggtatta ctgtcaaaat gaagatactc agcatgataa
    28861 acatgataaa gcagttgact ggttaataga gaatccagaa aagttcatgc gtgcttggct
    28921 agatggctat gatagcaaga aaaagccact ggaaagtaat gaggaaacgt atttaacggc
    28981 agaacaatat gactatgcta gaaaaacagg agattgggaa tctggtaaga ctttcaatca
    29041 cagaaaagat caaccaaaaa ttagtttttc agatatagcc gcaattatcg aaggtatcta
    29101 ctatggacaa gccgatgaag agatcttttc tatacaagat ttattagaat ttttgaacaa
    29161 aaataaggat agctttgtag aactaactga ttatgaggag gatacagcaa atggaaaatt
    29221 atgatccaaa tatgcgatgg ggtacacata cgcttaaagt ttcttttcaa cgttgggatt
    29281 acaagggatt tgtgactttt agaaaagctg gaaattgtaa aggattagat gtcttagcgt
    29341 tggatgaaga ctatctatat gaccatccat tgacggataa tccaatcgga tttggattgc
    29401 ttcctgaaga tgatgagggc aatgaatggt tcaaaatgat tcttacaaac gataaaggtg
    29461 atcaattatt tgtagaagat acttggtcat atttgagtga atatattgtt agcattaaaa
    29521 tcattgattt tgtagcagat aaagaaaaag agattggaga aggtaaatct aattactagc
    29581 taatgaatag caactttgga ggataagtca aaagaataaa aaaagaatac tgtgtgtcat
    29641 tgcagggatg tatctttgca tgatagtatc tgcggttacc atttattggt taggaaatca
    29701 gcaaaacagt ttaattgttg atctggggga gttaaaggtt ggattacgaa tgactagatg
    29761 gcttttatta gctcaaacag ttggtttagc catattgact tggatatgtg tggaaaaaat
    29821 aacatctaat aataatcaag agattgttga atcaacaaac ctaagaataa gaataactga
    29881 acaagcaatt gaaaagcaaa aagacaaaga aaaaaaggaa ataatgtcaa tttatttatc
    29941 tagtggagca tcattttttc atgaaataga ttcgatgaaa ctgagtagtc aagaaatcat
    30001 tgatagatgg aaaaacatgc ctctaggtgg tgagttaatc gttgaagata gtgatggttg
    30061 gtcagcttat aagaaggacg agattgtagc tatcacgatt ttgtttgaat agtaatatat
    30121 taccactaga taatctgaat atgttgatct gctagtgacg taccaaatgc gtttaataga
    30181 accttggtca caggcagaaa ttgataaagc agtaaaattg aaccgattat caaaatttaa
    30241 cgtattagga aatgcctttt aaaaatcgca atacacaaac agaaaaatac caaaaaatta
    30301 gcaatgaacg taggtaagaa catgacaata aataataata accctaacaa atataatgct
    30361 cttgtccaat gctatatcga aaacaaaatt acaatgcaag aagtcgctga tgaattaggc
    30421 aaatcaaaaa gcctagtatc acacgacttt aagcacaatg tttttccgaa cccgattgag
    30481 ctgaggaaaa aatttcaaaa gagagtttat caagaaatag ggaagtggat tgatgaaggg
    30541 aatgcaattg accctttaat tgaaaaatat ccttttttaa aaagtaaaaa taaaattcaa
    30601 aggttaattc gtcaaggcga tattcaagct aaagaacctg ttttgacaac caatgatttg
    30661 gctaaaataa atcttcataa acagattatt gaagactttg aaaaaaatct ttcaacaact
    30721 gaaattttaa aaaaatacaa tattccgaga ggaaagctaa catcgactct ttttagagaa
    30781 tatggagaat cggcagttac taaagcaaag gaagtagcga atgagagaaa aaaacaaaaa
    30841 tagtagtcga tacctagtag cgactgtagt ttttgtttgt gtattgattt tcctgtttga
    30901 ttttttgcag attggaaaaa gcataattgg aaatacattg agtgcaaagg aaatggttgc
    30961 tttaggtggt ttgtatgaag gacatttgtt cccgaatata ttcatttcta tcgtttctca
    31021 tattaacttg taccatttaa tttctaattt attgttctta gtagttcttg aagaagcact
    31081 gaatgatcaa tatgagtggt taacactatt gattgtttta atcatatcag gacttctagg
    31141 aagcttagtt ccttttctgt tacaaagcaa catcgtaagt atggggctta gtggaggtat
    31201 ttttggatgg attgctttat ttgcgattgc atacatccgc tttgatagta aggaacattt
    31261 attactaagt gtttttatat tattgataat cggcatttta ctggtatcta cttttgaatc
    31321 aggcgagaca aacgtcttgt cacatgtaat cggatttgtc tgtgggatga tcttgggatt
    31381 tattctaaag aacatttcat tgatcaagca aaagaattaa aagggagtgc taaaaatgcc
    31441 aaaaaaaaaa gaaaagaaaa ttccagtgtt tttgtctgtc tcagaaatgt tatcacttca
    31501 aatactgtta agaaaaaaga ttgaaacaat agacgaagaa gttagaaata aaagggctat
    31561 gtacgaacaa cgtgaagcgc taagagaacg aatccactat tttgatgata tacacactaa
    31621 aatctatgaa gcacgtacaa ataacgaaga cgaaagcaaa ttaggattag ctcaacaacg
    31681 aatatttgaa tggctaaata cgaatactga gcaagaaccg ttaagagcaa ttagtaatct
    31741 ttttgaattt ggaacgaagc attggtttaa cgcagtagaa aaggatgctg acttacaaga
    31801 agcctttgac acgctaagta aggatagcaa atccatgcga gatttattga ttacttatct
    31861 aaatgagcat gagtttgaac aaacgaaaac caaaaagaaa aataaagaat agaaagttgt
    31921 gatgaatcat gctattaacc ctgttaggtt atttatgttt aattcttgct ttttttgggg
    31981 caatcgctat aattattggt caatttcaaa caaataatcc gattatgcgt aacataggca
    32041 ttggaattgt gattgtaacc tttattgtgt ttaatgccac taagattttt ggaagtaacg
    32101 ataaacaatt tggtatatcg ggagttaata atagttatgc tccagattct ttgggaaggg
    32161 tagtaataga tggaacattt gaaaatgtaa cgagttataa aaatgtttcg ctgacagtga
    32221 aggaagatgg caagaaagca tcagacgacg ttctcgctac tattaagccg tctcaatcac
    32281 aatttgaagt gttttataca gttaaagaga atagccctgt acacaagctg acattggttt
    32341 ttaacgttga tggagaagaa tactataaag atgtaaaaat aaataaaaca tcaacgaaaa
    32401 agattatcga atcagcgaaa aaagaagtag ctacagaaga aagtacaact gaatcaagtt
    32461 ctactgtcga agcggaacta ccagataaaa ttgattttga tcctgaaaaa gtcaaatcgt
    32521 ttgaatctgt ttctggttct atggctgatc ggtttaacac tgaagtcttc aaagctatca
    32581 aaactgttaa attggatact gaaaagcaaa tgattaatgt taccttattc aattcagttg
    32641 aatctatgga tcaggataaa aaagttacgg ttgcaagaga actaggaaaa agagtaattg
    32701 gtttgtatcg tggtactgct aaaccagatt cagacggtgc agatttgcca gttcatgtag
    32761 tttatgaaga cggtaaagtt tttggagatt ctacagcaaa cgaagcatta acgattaaat
    32821 tggctaaata gccagaaagt tataataaac aaatggtgtc acaccaataa tatataggtg
    32881 tgacaccttg gagatgatag ctgatggtag taaataaaga aaaagttaga aagtatgtga
    32941 ctttaaaaat agcttctgtt aaatatttag aaaagcgagc taaagaagaa gaaagagcaa
    33001 gaggtaagaa agtaacagtt tcagagttgt tagaagaatt gatcgagaat gatcaaacaa
    33061 taagacgtgc atttactaat aggtctatca gataacaata taattaataa aaaagaaaga
    33121 gtgatttggt cttagactaa atcactcttt ttatataaag tttctttaca ctcattccga
    33181 ataatgttaa aattctttat atgatatata gttccttgtc agaggaagag ataaccagca
    33241 atattggagg gataataagt ggaaaacaat aatgatatta gacattttag cattggggaa
    33301 agagttacaa cagtaagtga attatcaaag gattatagag ataaagaggg aacgattatt
    33361 tctcttaata agaatcgaag aggcgtttgg caatatgttg ttgatttagg tgatggcgtt
    33421 acagttgagt gtaaagatag tcaactgatc agaaataatg gcagtcattc cattgaaaaa
    33481 gcaattcttg tatacccaaa agtatcaagt aagatcatga atgactggtt gcttggaaaa
    33541 tttggtgagt acaataaaaa agaaatcgca gaagtgatcg gcaaatctta tccaacagta
    33601 ttagggtatc taaaaaagat aacgagtaaa gaagcaaaaa ttgaggatgt tttaacagta
    33661 agagagcttc aatcattaat cgagtatcgg aataaacaaa taacaaatcc tgagtacctt
    33721 agaaaagaag atggtctatt gaaacaattg gaacaagtaa ataaaatccg gaagatgcaa
    33781 aaggtagctc ctttaagcct tgataccttt aaaaaaatct atttgaaaga gatcaaaaaa
    33841 gactaatgtg gactgtaact ttaccgttcc aacctgtatc tgcaccaaga ccaagtgcaa
    33901 gaaggaatgc tgctgatgaa actaatgacg tagcagagaa aaggatttca acctactatg
    33961 ataaaaagta tcttgattat ttgaaaaaaa taaagagctt tatcgaagat caagatttat
    34021 tagatgatga attttactcg attgtaaatg atcctatggg cgcaattatg gaagtggact
    34081 tttactacca gataccaaaa agctataaaa aagtctataa cattatgaag acaacagcgc
    34141 cagatttaga taatttagta aaaagtgcta tggatggtat ttttaacatc tcagctatac
    34201 gagatagcca tatcacaggc ttaattgctt ttaaatataa tgtggcgaac gaaggaaaaa
    34261 cagttgtgag gatcaaacga tattcagaat ttgagtggga tacttctgaa ggattgaacg
    34321 gagatatatg ggaagctaca tttgatttta aaccagtagc aacgccaaga ccaaagtcta
    34381 aatttagagg aaatgggatt atcacttact atccaaaaga gtacaacgac tatttggaaa
    34441 atatcaagaa tacgcttaaa gagaaagatt tggtaaatga tcaactgaaa aaggtaatga
    34501 atgctcctat gggggttata gctcagatag attattttta ccaagtgaga aaagataaga
    34561 aaaagcttga ttcactgatg cgtacttcac agccggatat tgataattta gtcaaaggaa
    34621 cattggacgg aatttttaac aaggaaatag gcatcaaaga tagcagggtt gtagggttaa
    34681 ttgcttttaa atacaatact tttgaaaagt cgaaaacaaa cgtgagacta caggagatgg
    34741 gctgatgaat aataatgaaa aaattcttca tgtacttgat agctttgaaa taattcaaga
    34801 agaactaaaa aaatatcggg atgttttgga acaaagatat gattttgtca atcagcaaaa
    34861 gagtaatcac atggatttca ttctcaatat gaatgacttg aagaagaaat tagttgaacg
    34921 aaaagaacaa gaaaagttga tcaaagctta ctttgaactc ggtgaaaaag aagttaaaaa
    34981 tgcaatggaa ctgaatgaag agcgcagggt tttagatcag ctgttagaac aattattggt
    35041 gatgtttcaa aaaggacgaa tagatgagga tttaattgaa gaaggattga gaaaatatcc
    35101 ttcaaactca ggtatcggaa tagtgctgaa agcgattgat gaagaagaaa ttgaagcttt
    35161 cataccgcca gaggattttg aatcggcaat ggaatatata aaatattata gccaagggat
    35221 cactgctttt agagagtttg atcctgaaga tgttattcat gacttgaaca acctaaaaga
    35281 atggtgtgaa agttatggag tcgatgattc cggattggac tacttgatca gtattatgga
    35341 aatcgaagaa gagatgccgg ataagcctga tccaacagat attttagaat tgatccatga
    35401 agctagaaat ccaattgcct atatttctag aggatatact gtattggaat actataagcc
    35461 ttatatatca gcgatgaacc atttaagacg tgtattaagg gaaaaacgtg aataccgctc
    35521 agtgttgaat gcaacgaata gattagaaaa agctgtttca gagctagatg cttattatcg
    35581 tgaacattac ctgcaagcag gtggtatgcc aagaaatacg aaagcaaata tcagtaggta
    35641 tataaaaaaa gctgagtagg cggagttagc ccataaaatg gcaaaaggta acctgaaagg
    35701 ggcattttga atgaaaaggg atgtttttga attgtacgta ttagaacgtc tagaagacgg
    35761 catgatggca caagagataa ttgatgaaat tgatgatatg atcagcagat ttggtcaatt
    35821 ggagttgaat gatggaaaca aaaattcggt agtgctaaaa caattttggt tgaacaattt
    35881 ttcgtataag gattttatca aagaaaaggc aaatacattg tactgactaa attcacgagg
    35941 agcagtgatg agagcttatt gctaagagca gttaggctct tttttgtttg tgtaaaatta
    36001 tttgttttat aatacacatt tatacacaaa aaaatattga cagatagtac acaaatgtgg
    36061 taggatatat ttgtaagcaa gttagattaa caagttaaag gaagagcagt tatgaaaaaa
    36121 gaagaactaa tagatatatt tcaaattgtt gaacgagcaa ataatatggg aattatgttt
    36181 tttgatcgta tttctttaaa gatggattta acagaattag gcagaagtcg cccatcctct
    36241 ataggtgggt gatgaatgcc gttcggtatg agggttaccg ttggtaactc gaagaccgac
    36301 aactaaggcg tattgccttt ttattttgt
//
LOCUS       DACCVZ010000021        34962 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.021, whole genome shotgun sequence.
ACCESSION   DACCVZ010000021 DACCVZ010000000
VERSION     DACCVZ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.021"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            156..1862
                     /locus_tag="IVW63_001061"
     CDS             156..1862
                     /locus_tag="IVW63_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAP7859348.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="IVW63_001062"
     CDS             complement(2020..2922)
                     /locus_tag="IVW63_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP7859349.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3623)
                     /locus_tag="IVW63_001063"
     CDS             complement(2919..3623)
                     /locus_tag="IVW63_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HAP7859350.1"
                     /translation="MKKNMDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKG
                     EETKIEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSE
                     HIINGKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVN
                     PDVFFPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPI
                     QPLNGREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="IVW63_001064"
     CDS             complement(3654..4295)
                     /locus_tag="IVW63_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP7859351.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="IVW63_001065"
     CDS             complement(4333..4647)
                     /locus_tag="IVW63_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859352.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5264)
                     /locus_tag="IVW63_001066"
     CDS             complement(4635..5264)
                     /locus_tag="IVW63_001066"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAP7859353.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="IVW63_001067"
     CDS             complement(5271..5987)
                     /gene="pyrF"
                     /locus_tag="IVW63_001067"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAP7859354.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(5984..6916)
                     /locus_tag="IVW63_001068"
     CDS             complement(5984..6916)
                     /locus_tag="IVW63_001068"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAP7859355.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="IVW63_001069"
     CDS             complement(6913..7689)
                     /locus_tag="IVW63_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAP7859356.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="IVW63_001070"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="IVW63_001070"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAP7859357.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMSMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /gene="carA"
                     /locus_tag="IVW63_001071"
     CDS             complement(10933..12009)
                     /gene="carA"
                     /locus_tag="IVW63_001071"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAP7859358.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="IVW63_001072"
     CDS             complement(12014..13294)
                     /locus_tag="IVW63_001072"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAP7859359.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="IVW63_001073"
     CDS             complement(13313..14239)
                     /locus_tag="IVW63_001073"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HAP7859360.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="IVW63_001074"
     CDS             complement(14252..15535)
                     /locus_tag="IVW63_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAP7859361.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="IVW63_001075"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="IVW63_001075"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAP7859362.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="IVW63_001076"
     CDS             complement(16323..17234)
                     /locus_tag="IVW63_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP7859363.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /locus_tag="IVW63_001077"
     CDS             complement(17231..17695)
                     /locus_tag="IVW63_001077"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAP7859364.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="IVW63_001078"
     CDS             complement(17700..18398)
                     /locus_tag="IVW63_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP7859365.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="IVW63_001079"
     CDS             complement(18385..18771)
                     /locus_tag="IVW63_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859366.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="IVW63_001080"
     CDS             complement(18918..20588)
                     /locus_tag="IVW63_001080"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAP7859367.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="IVW63_001081"
     CDS             20771..21004
                     /locus_tag="IVW63_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HAP7859368.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="IVW63_001082"
     CDS             complement(21103..21534)
                     /locus_tag="IVW63_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HAP7859369.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="IVW63_001083"
     CDS             21613..22026
                     /locus_tag="IVW63_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HAP7859370.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22064..23212)
                     /locus_tag="IVW63_001084"
     CDS             complement(22064..23212)
                     /locus_tag="IVW63_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAP7859371.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23334..23930)
                     /locus_tag="IVW63_001085"
     CDS             complement(23334..23930)
                     /locus_tag="IVW63_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP7859372.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="IVW63_001086"
     CDS             complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="IVW63_001086"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAP7859373.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27160..27591
                     /locus_tag="IVW63_001087"
     CDS             27160..27591
                     /locus_tag="IVW63_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7859374.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27636..28985)
                     /locus_tag="IVW63_001088"
     CDS             complement(27636..28985)
                     /locus_tag="IVW63_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP7859375.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29055..30218)
                     /locus_tag="IVW63_001089"
     CDS             complement(29055..30218)
                     /locus_tag="IVW63_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859376.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30347..30670
                     /locus_tag="IVW63_001090"
     CDS             30347..30670
                     /locus_tag="IVW63_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859377.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30853..32202)
                     /locus_tag="IVW63_001091"
     CDS             complement(30853..32202)
                     /locus_tag="IVW63_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7859378.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32271..33224)
                     /locus_tag="IVW63_001092"
     CDS             complement(32271..33224)
                     /locus_tag="IVW63_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAP7859379.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33326..34516)
                     /locus_tag="IVW63_001093"
     CDS             complement(33326..34516)
                     /locus_tag="IVW63_001093"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAP7859380.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9953 a         7641 c         6120 g        11248 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgacatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaact atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat
    22081 tgtgatcaaa cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta
    22141 agattctttc tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt
    22201 gcagcgtttt tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt
    22261 caagaagaat ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca
    22321 ttggatccaa gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca
    22381 gatcaataat cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg
    22441 atgcaaagcg tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat
    22501 catcgcaagc atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc
    22561 ctaatagttc gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg
    22621 ctaaagcaaa acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg
    22681 aaagcaatac agccagtgta gtaaagacat cattataact atctgttgct gtagctctca
    22741 atgtttcaga atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca
    22801 aaaagatgga aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat
    22861 ggatgatttt ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg
    22921 aaacaaataa cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg
    22981 ctggctttgc agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata
    23041 gactgttcac tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct
    23101 tagagacaaa caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt
    23161 ttgtccgctg ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta
    23221 ccccttctag tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc
    23281 ctctcttcct ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct
    23341 ggtttcaacg gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca
    23401 cctattgctt ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga
    23461 gcagagtcta caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct
    23521 aacactaaga ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt
    23581 attgatttat ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt
    23641 actctgggaa ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt
    23701 ggcatggcat aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca
    23761 tcttttgggc ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta
    23821 atgaatccta atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct
    23881 aacaagatcg cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc
    23941 ctttttattt atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga
    24001 atccgaccat ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt
    24061 tgtcttcgcc cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac
    24121 gtaaacgccc tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc
    24181 agcaggattt ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac
    24241 tttcggtgcg attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt
    24301 cgtcattgcc gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc
    24361 tgaaatattt ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac
    24421 ttttacttgt gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc
    24481 accagcttgt tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct
    24541 tacttgctgt tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac
    24601 aattgttgct acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt
    24661 acttgttaca gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt
    24721 gaagattccg atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca
    24781 gccgccaata tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc
    24841 acccatgttt ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca
    24901 gattttttcg ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa
    24961 gtgggtaaag tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg
    25021 ctcgccaagt acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat
    25081 gatccgattg cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg
    25141 tgcttttact tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac
    25201 aactgctacg atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc
    25261 catttctgca tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc
    25321 attcaaaaga gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt
    25381 gtatccaatg aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat
    25441 tgatttttca gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc
    25501 aaaaccagca tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac
    25561 cgggaagcca tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt
    25621 ttcgtttttt acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc
    25681 attgaaacgt tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac
    25741 ttcaggataa taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc
    25801 ttgttcaata cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac
    25861 ataccctctc ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg
    25921 aatatgatct gcgattactt tgtaagaaat atctgttact gggttttcac catattttac
    25981 ttgtttgctt agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt
    26041 cgttgacgca tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt
    26101 tttatgagga agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa
    26161 gttccagatt tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc
    26221 tgctaaatcg ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg
    26281 gcctgcaccg atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc
    26341 aacttcttca tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag
    26401 tttttctgga tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat
    26461 ggcttcattt ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg
    26521 gtgccgtgct gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt
    26581 tgtgattctt ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac
    26641 accagagttg atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc
    26701 aatcgtatgt cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact
    26761 taattgtttc atgtcattac ctgctttcta taaattaaat acaaaaaaac accatcacag
    26821 ccaaggacga aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta
    26881 aactcgataa cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg
    26941 attagtgact attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat
    27001 catatccttt tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat
    27061 ttttattttc atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga
    27121 atcaatacat ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg
    27181 gatgaatgga tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa
    27241 gggattcctg cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta
    27301 tttcttgatc aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc
    27361 ttcaagccgg aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag
    27421 ttgcttgaag ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta
    27481 gctgaaatga cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct
    27541 tttattgaag atgaagtact ttgtatcgga atgaaaaaaa gtctagctta aaaacaagag
    27601 attgtgacac gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt
    27661 ttacgagcag tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct
    27721 gcaattgccc aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc
    27781 acaagaccaa tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta
    27841 ttacgatcgt atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg
    27901 cccaattttt ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc
    27961 gttcctttta agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct
    28021 tctggaattt ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct
    28081 aaatcagtcg ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt
    28141 ctctctcttg gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag
    28201 taatcggcaa tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga
    28261 tgaccaattg tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc
    28321 agccaatttt caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga
    28381 ttttccatgt attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact
    28441 aaaaactgca gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc
    28501 atatccaatg tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc
    28561 gcttgttcat tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt
    28621 tggtgatgca gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca
    28681 cggatctccg gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct
    28741 agttccctac ttggagctgt aataacaact tgtacttcct ctttttctgc attgattttt
    28801 tcaaacaaag gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg
    28861 atattttttc cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg
    28921 aagccctttg cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta
    28981 ttcattcgtg cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa
    29041 gcgtttttgc tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca
    29101 gtatatgtgt gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc
    29161 aagatattta aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca
    29221 ctcatctgca acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac
    29281 cagcttaaac cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa
    29341 gaaattcgtt cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc
    29401 catccattgg ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac
    29461 cagatatgag aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc
    29521 aaattaataa gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat
    29581 gagacagtct ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata
    29641 aatgtaaata acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa
    29701 tcattcacat caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc
    29761 gtcaattcaa aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc
    29821 cggaaataat atcttaaata aatgccaaac ggtatgagta ataaaacatt aaaagctggt
    29881 tccaaaaata cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat
    29941 accgtgttgt ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct
    30001 gtcatttggg caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac
    30061 aataaataaa aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac
    30121 tttcgatatt cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca
    30181 atcagcgcaa aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg
    30241 tatctctctt atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct
    30301 catttctttc aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta
    30361 ctttgttttt ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag
    30421 aaaaagaact acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct
    30481 agtcttcaat cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca
    30541 tgctttgtct aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc
    30601 tggttgcttg gttttattaa atatttatcg cggcgtacgc cgaatagttc agttacgcaa
    30661 atcaaagtaa aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca
    30721 tcgtagacaa aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca
    30781 cgtactcctc atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt
    30841 cgaatgtttt agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa
    30901 tactatcccc atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt
    30961 ccctccaatg attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa
    31021 caaatcaggt tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat
    31081 ccaaatgaca aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc
    31141 aatagcgatg actagctcta agatacctgc ggctacagga actttagttt tatcatgaag
    31201 tttagcaaag agcttgctaa aaggcaggtt gttttctttt gccataacat aagggagacg
    31261 cattccagta agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt
    31321 gaccagtctt ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct
    31381 gtttcctgcg actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata
    31441 aacgatcatg attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt
    31501 tttcaattct cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc
    31561 tagcaagccc gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa
    31621 cagttggaag tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg
    31681 aataagcttg cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa
    31741 attgatcaac aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga
    31801 aagaccaaat agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc
    31861 tggaaaataa atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat
    31921 ccgttcgata tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc
    31981 tgttagtcct gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact
    32041 ggcggatcct gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac
    32101 tgtgcccata acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc
    32161 tatttttact tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata
    32221 ccatagccaa tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc
    32281 tctaccaatt tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat
    32341 ttcggcgaaa agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat
    32401 tctgctattg actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt
    32461 ttttgaatag atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca
    32521 tttcgatgaa ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca
    32581 tctggcatat acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct
    32641 tctttgattg ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag
    32701 gttgcataag aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca
    32761 taataataat cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga
    32821 cgctgaagag tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt
    32881 gaacttggcg taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc
    32941 ccagtcacgt tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga
    33001 gcagccaaat gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg
    33061 taatccatta catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt
    33121 atatctgtcg caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct
    33181 gaaccaattt gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat
    33241 cttttttact actatcttca gatgattaac aatatatgcg tgaacatgtt ctctaatttt
    33301 aaatagacga aaaaactaaa tttagttaaa taatttccat ttcttttcct attttttgat
    33361 aaactgctac tgcttcatca agcatttccc tcgtatgttc cgcagtcggc atatttctga
    33421 tcctgcctgt cccaagaggc acagttggat aaacgattgg tttagcataa atcccatgtt
    33481 cgatcagctt cttagagaaa gtctgagtca ctttttcgtc tcccaaaatg actggagtaa
    33541 taggtgtttc agacataccg atgttatagc ctactttttt caattcttct ttaaaataat
    33601 tagcattttc ccaaactttt tcgacaagtt ccggatgttc ttgcatcaaa gtaatcgaag
    33661 ccaatgcagc tgcagctgca cctggagtta gcgaagtaga aaataggaat ggccgacttc
    33721 tagctttcaa ccagtcgatt agtgttttcg atccagctac ataaccccca acaacaccta
    33781 tagctttcga taacgtgccc atttgcatat cgattttgtc gcttaatcca aaatgcttga
    33841 cggttcctgc accttttcca gttacgcctg agccgtgcgc atcatcgacg taggtgatca
    33901 gtccatattt ttcaacaatc ggaataattt ccggcaatcg tgcaatgtct ccatccatgg
    33961 agaaaacacc atctgtgata tacatgattt ttttatattt cttactttct atcgcttcct
    34021 ttgctttttt ctcaaggtct ttcatatctt gatgtttaat tcggatgatt tttgctccgg
    34081 ataagcggca accgtcaata atagatgcat ggtttaattc atccgataag atagcatctt
    34141 cttttgtcat tactgcagag atagcgccca tattgcagtt gaatccagat tgaaaggcga
    34201 ttgctgcttc tgtccctttg aattctgcga ttttttcttc taattgctga tggattttca
    34261 gcgaaccatt gatcgttcgg actgctcctg ctcctacacc ataagtttcg gttgcttcaa
    34321 tacatgcttt tttcaattct tcgcgattgg caaatccaag ataattgttg gatgctagat
    34381 tgatcatctt ttttccgtct acgatgatac aagcaccatt ttcactttct agtatgtcga
    34441 tcgtattgta taaccccttt tctttcagtt gatccaattc tttctctaaa tacattgtta
    34501 gttctttgga agacattgtc tccacctcca tattcatctg tcttgcagaa cataccaaac
    34561 atatatcgtg tcattcatct acaaagcaag tatgctatat ttttgataac gcttacactg
    34621 attatgagaa ttatttaacc acatttttta tttacagtat ctttttactt tcaaatgact
    34681 tatatagtat gaacaattac cttttagata atgatctatt ttactctacc tgggcagata
    34741 aatacaacac aaccattgat agaagccctt tcgttaaaat caattgtatt ctgaatattt
    34801 aatttattta ttgcatagac caataaaaat acataaaatt tccatcttcg tttatcagca
    34861 atttttaatt ttactctctg aatatttctt aaaagtttta cttgttgaat tcgaaaaaag
    34921 gactgtgaca aaagtcttgt cacagtccta ttcttccgaa ta
//
LOCUS       DACCVZ010000022        34897 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.022, whole genome shotgun sequence.
ACCESSION   DACCVZ010000022 DACCVZ010000000
VERSION     DACCVZ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.022"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(54..1283)
                     /gene="rpsA"
                     /locus_tag="IVW63_001094"
     CDS             complement(54..1283)
                     /gene="rpsA"
                     /locus_tag="IVW63_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAP7859381.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(1418..2098)
                     /locus_tag="IVW63_001095"
     CDS             complement(1418..2098)
                     /locus_tag="IVW63_001095"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAP7859382.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(2147..2782)
                     /locus_tag="IVW63_001096"
     CDS             complement(2147..2782)
                     /locus_tag="IVW63_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP7859383.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(2848..4251)
                     /locus_tag="IVW63_001097"
     CDS             complement(2848..4251)
                     /locus_tag="IVW63_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAP7859384.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(4238..5269)
                     /locus_tag="IVW63_001098"
     CDS             complement(4238..5269)
                     /locus_tag="IVW63_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859385.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            5300..5521
                     /locus_tag="IVW63_001099"
     CDS             5300..5521
                     /locus_tag="IVW63_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAP7859386.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(5686..6423)
                     /locus_tag="IVW63_001100"
     CDS             complement(5686..6423)
                     /locus_tag="IVW63_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAP7859387.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(6576..7916)
                     /locus_tag="IVW63_001101"
     CDS             complement(6576..7916)
                     /locus_tag="IVW63_001101"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAP7859388.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(8153..9676)
                     /locus_tag="IVW63_001102"
     CDS             complement(8153..9676)
                     /locus_tag="IVW63_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAP7859389.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(10054..10665)
                     /locus_tag="IVW63_001103"
     CDS             complement(10054..10665)
                     /locus_tag="IVW63_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP7859390.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(10788..10913)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(10995..11711)
                     /locus_tag="IVW63_001104"
     CDS             complement(10995..11711)
                     /locus_tag="IVW63_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAP7859391.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(11717..12286)
                     /gene="scpB"
                     /locus_tag="IVW63_001105"
     CDS             complement(11717..12286)
                     /gene="scpB"
                     /locus_tag="IVW63_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAP7859392.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(12270..13067)
                     /locus_tag="IVW63_001106"
     CDS             complement(12270..13067)
                     /locus_tag="IVW63_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAP7859393.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(13037..13408)
                     /locus_tag="IVW63_001107"
     CDS             complement(13037..13408)
                     /locus_tag="IVW63_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP7859394.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(13427..14314)
                     /gene="xerD"
                     /locus_tag="IVW63_001108"
     CDS             complement(13427..14314)
                     /gene="xerD"
                     /locus_tag="IVW63_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAP7859395.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(14410..14883)
                     /locus_tag="IVW63_001109"
     CDS             complement(14410..14883)
                     /locus_tag="IVW63_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP7859396.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(14988..15851)
                     /locus_tag="IVW63_001110"
     CDS             complement(14988..15851)
                     /locus_tag="IVW63_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP7859397.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(16047..18146)
                     /locus_tag="IVW63_001111"
     CDS             complement(16047..18146)
                     /locus_tag="IVW63_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAP7859398.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(18366..19475)
                     /gene="rpoD"
                     /locus_tag="IVW63_001112"
     CDS             complement(18366..19475)
                     /gene="rpoD"
                     /locus_tag="IVW63_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAP7859399.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(19499..21340)
                     /locus_tag="IVW63_001113"
     CDS             complement(19499..21340)
                     /locus_tag="IVW63_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAP7859400.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(21522..23915)
                     /locus_tag="IVW63_001114"
     CDS             complement(21522..23915)
                     /locus_tag="IVW63_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP7859401.1"
                     /translation="MFLILEHARLKHVIIFESWRKMEKKKMNGLTQQEVVQKMASGQQ
                     NDYQEDASKSTKQIFSDNILTLFNFLNFGIGICLLFVGAYSNMAYLAIIVVNIVIGIY
                     QEIHARNLVRKLSIVSQSEVLVIRDGKEQSISTKELVLGDLVKIGAGEQIPADLQVIS
                     GRAEANEALLTGESDLIVKETGAELLSGSFLTSGSVMAEVIRVGADNYAVRLTSEAKT
                     HKAIRSELVDSIRKVSKFTSFVIIPLGIILFLEALFIRDASIKISVIASAAALLGMLP
                     KGLVLLISIALTTGVTKLAKKRILVQDMYSIETLAHVDTLCLDKTGTITEGKMSIQRV
                     EALHPLYEKAIPEIMGTYLAESSDNNITMRAMRDYFELSNRYDVTNKVAFSSDRKWGA
                     MEFPELGVVYVGAPERLVEEDRLPDSLKTAQANGYRVLMLGIAPNQQLNEEKPAFVEP
                     VALFEIDDPIRKNAQETLAYLHEEGVDLKVISGDNPFTVSNIARRAGLPNYDAYVDLS
                     QITEEMEVREAAHRYTVFGRVSPQQKKLLVNELKESGRTVAMTGDGVNDVLALREADC
                     SIAMAEGDGATRQIANLVLLDSDFTTLPEVLFEGRRVVNNVTKVSGIFFIKTIYSFIL
                     SIICAVTAIGFPFIPIQITLIDLAIEGYPSFFLSFEQDKRKITYRYLPTALINALPNA
                     LLVVVNIIAVYLLGKTFAWGNAETTTLMYYLLIGISCMAVVKACYPFNPLRIFLAVTT
                     IVGIYVAAMLFHGILEVNLGLGESVGYFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(24022..24882)
                     /locus_tag="IVW63_001115"
     CDS             complement(24022..24882)
                     /locus_tag="IVW63_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HAP7859402.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(24941..25462)
                     /locus_tag="IVW63_001116"
     CDS             complement(24941..25462)
                     /locus_tag="IVW63_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAP7859403.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            25782..26501
                     /locus_tag="IVW63_001117"
     CDS             25782..26501
                     /locus_tag="IVW63_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP7859404.1"
                     /translation="MKKEKKYAKMPDGSEIYYEKSGQGFPLFLLHGNDGSGRFFSEQV
                     PVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEKIDQADFLGFSDGAN
                     LALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVWLLSLFRPSLRKNLL
                     VIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKTIPKASFVLVKEQGH
                     ELARKDPERFNREVLQFLSET"
     gene            26527..29118
                     /gene="mprF"
                     /locus_tag="IVW63_001118"
     CDS             26527..29118
                     /gene="mprF"
                     /locus_tag="IVW63_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAP7859405.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(29306..30493)
                     /gene="tuf"
                     /locus_tag="IVW63_001119"
     CDS             complement(29306..30493)
                     /gene="tuf"
                     /locus_tag="IVW63_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP7859406.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            30861..31217
                     /locus_tag="IVW63_001120"
     CDS             30861..31217
                     /locus_tag="IVW63_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP7859407.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(31458..32462)
                     /locus_tag="IVW63_001121"
     CDS             complement(31458..32462)
                     /locus_tag="IVW63_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAP7859408.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            32628..33479
                     /locus_tag="IVW63_001122"
     CDS             32628..33479
                     /locus_tag="IVW63_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAP7859409.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            33496..33741
                     /locus_tag="IVW63_001123"
     CDS             33496..33741
                     /locus_tag="IVW63_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859410.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            33928..34632
                     /locus_tag="IVW63_001124"
     CDS             33928..34632
                     /locus_tag="IVW63_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859411.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT         9843 a         7317 c         6026 g        11711 t
ORIGIN      
        1 aaaaactgag acaaaagcag ctgctttcat ctcagtcaca gatacaaaat caattatttt
       61 tcagaatcat cggttgcttt ttcttctact tcttctttca acgcatcacc taaaatgtct
      121 cccatagtaa atccagtatt ttcttctggt aattcataag actcaacatt ttttggttct
      181 tcttctgaag ctggtttttc ttctaaagct ttgatactca atgcaatacg atgttcttct
      241 ggatggatct ctaatacttt cactttcact tcgtcacctt catgaagcac ttcatgtggt
      301 gtcgcaatat gtttatgtga aatttgagag atatggacta gcccttctac tccagggaac
      361 acttcaacaa aggcaccgaa gcttgtcaaa cgtttaactg ttccgtctaa tactgtgcca
      421 actggagctt ttgtatcgat ttctgaccaa ggtccaggct gtgtgtcttt gattgacaag
      481 gaaacacgtt cttgttcagg attgatagac aacactttga catttacatc atcattgaca
      541 gccaatacat cacttggttt tgctacatga ctatgtgaaa tctctgagac atggactaga
      601 ccgtcaattc cgcctaggtc gacaaatgcg ccaaaatcag taagacgtgc aacacgtcca
      661 ctgagaacat ctccctcatg gatagttgaa agaatttctt ttttcttttc ttctctttcg
      721 ttttccacta ccgctttatg cgataagatc aaacgatttt ctgatggttc gatttcgatg
      781 attttaaagc tcaatgtttt gcctttatag tctgaaaagt ctgcaacaaa atgatcttcc
      841 accattgatg cagggacaaa accacgtaca ccgacgtcaa cgactaaacc gcctttgaca
      901 acatttgtaa caggtgcttc gatgaccttg ccctcttgga aatctctttc gatatcttcc
      961 caaacttttt tagcatctaa acggcgtttt gaaagtagat agctgccgtt ttctttatct
     1021 ttgccgatcg tactgataac gactaaatct aatacatcac cgacttttac tacttcgctg
     1081 atatcttcta ccggcaaagt tgataattct tttgccggaa cgactccttc aactccagcc
     1141 ccttcgattc cgacaatcac ttgtttgtct tcaatgacta aaacttcgcc cttaacaaca
     1201 tcgccaactt ttacttcttg tacgcttttc attgcgtctt ccattgactg gttgttctct
     1261 tgattttgat caaattctgt cataacactt gtcctcctaa ccaacattct gccgtaagta
     1321 cggtactgtt tttagtttaa ttgattattc aaaaaaaata aagcgatttc gttcgttttc
     1381 cttgaaaaaa caattgtttt tcattttttt tcttaattta aaaaagaaga taaccttttt
     1441 tcaaaacaac agcttttatt gctgcaacga cttctggaat cgatttgcca gtcgtatcga
     1501 tacgaacagc atcctctgct tgcttcagcg gagagacgtc ccttgttgaa tcataatggt
     1561 ctctttcctg tatctctttc gtcagtgttt caagatcagt cggaattcct ttttcttggt
     1621 tctctttgaa acgtctttct gcacgctcac ttacgcttgc tactaaaaag attttcactt
     1681 ctgcattcgg taatacagct gtcccgatgt ctcttccgtc catgacaacg ccaccgcgtt
     1741 cccctatttt tcgttggaca gcaactaatt cttctctgac ttttccatgt gcagagactt
     1801 cagaaacagc ttttgtgaca tctggttgac ggatttctaa agtcacatct tttgatgcta
     1861 tgaatacatg ctgtccatct tcttgttgcg aaaaagagat aggatacttt ttgatcagcg
     1921 aaactagccc ttcttcatct gaaaaagata cattgttcgt aatagctaaa taagttactg
     1981 cgcgatacat ggcaccggta tctgtataaa tataattcaa ttcttttgct aatatcttgg
     2041 caacggtact tttcccagat gaagcaggcc cgtcgattgc aatactgatt tgtgtcatga
     2101 tataactcct ttttctcaga aaaaaagccg caaagcgcgg ctattattat ttaattctta
     2161 attcttgacc agggtaaagc ataaagttgt ttggatctaa gccattcaat tcaaacaatt
     2221 gatcagtggt gatccctgca cgctcagcca cttgttttgg accttcgcct gcttgaacag
     2281 tcgttgttga accggctgca gctgatgaag aaggtgttgt ttctgctgca ttgctgcttg
     2341 aatcccctgc ttgataagtt gcctcacttg aggaagtcgg tgttgtctct gctgcaatac
     2401 tgctttctga cgttacacct gtatcttgag acacagtaga ttcttccgcg attgtactag
     2461 attctactgt tgaagtctca gttgactcct cttttgttgt acttgtagaa ctttctacta
     2521 ctgatgtcga agtttcagaa gaagttgctg ctgttgcatt gttgcttgat ccatttctga
     2581 tccagaaata agcacctgct ggaatagcga tacataagac cagtaaaatc aaaaatagcg
     2641 aaagaaataa tgtatttcct ttcttttgtt gtctctgaga acttcttgat gaaacttcat
     2701 catctgtatc gtagattggt tgttcccatg gttcttgtgt ttcgttattt tctgtagatt
     2761 gatgtctatc ttttctgctc actgttttac ctcctaaact ctatcgtgtg tattatacca
     2821 taggaaaaag tgtcttgtcc taaaaaatca atgttccatg ttttttttaa ataaatttag
     2881 taaaatcgtt ccccaatgaa gttgttcagt cttagaaaaa agcttcctct ttggcagaag
     2941 ttctgctttt gctccatcaa tatcacaaca attctgcggc ttttcggaga gtttttcgcc
     3001 aaaataagct aagatgaatt ttctgcggca gttttcttca ttaatatagc gaagcatctg
     3061 ctgcaggcgg aattcttttt ctttttcctg acgtttgagc cgttccaccc aattttctgg
     3121 tttttcagac tgctggatca gctccatcca ttttttttgc agctcatcaa agggagcttg
     3181 ctctgtggca tattccaaat aaagctcaaa actttgtcgc tgttctctag aaagttgatt
     3241 aaagaaataa tggatacgtt catccccact ttgataaaaa agaattgctg cactttcttc
     3301 ctgatctctg cctgctcgac cgatttcttg tacatagttt tctagactgt ctggcaaatc
     3361 ataatggacc acataacgga tatcagattt atcgatcccc ataccaaatg cattcgtagc
     3421 aatgagaaac tgcagctgat tttttacaaa ctgctgttga agttgtcttc tttgagctgc
     3481 atcaagacca ccgtgatagt atccaactgt aaaacgttcc ctgaataaat gatacaatcg
     3541 ttcgacttct ttttttgttg cacaataaat gattgccgct ccttgtgctc tttccatgaa
     3601 gtgttcaagt tcttgttctt tttgctgcgt tttccgaaca aaaagcgaga tattttgccg
     3661 attgactgat tgtctgatct cttttggtgg tcgatcaaat agtacatgac gtatatctct
     3721 tgctactaaa tctgttgctg tcgccgttag tgccagtgtg accgggtttc ctaaaagctt
     3781 tcggattttt cctaactgtt gatattctgg acggaaatca actccccatt gagacacgca
     3841 atgagcctca tctactacat ataacgcaat attttgtttt ttcagatgct ctaaaagaga
     3901 aggattagtc aacatttcgg gactcaaaaa caaaaattta tattgcgata gatgacggag
     3961 gacgtatctt ctttcagatt gcgaaagtaa actattgaaa gcagctactc gtttctcccc
     4021 tcgtttttgt aattgcgtca cttgatcttc cattagagaa agcagcggtg acacgatgat
     4081 gaccagacct tccattaaat accccgtcaa ttgatagcaa aggctttttc ccgttcctgt
     4141 aggcaaaata gcgagagtat cttctccatc aagcaacgcc tgaataattt cttcttggcc
     4201 gggacgaaat gaatcaaatc caaaatattt ttttaattca tttattaaca ttctgtatcg
     4261 cttcctttct caatagatag atttgataca aacgaaattc tccataatct aattgtccat
     4321 ctacattcca ttcgctaaag cgccactctc gcacggaatc cttatttggt tccaaacgtt
     4381 cgattgtttc tgcagagaga atccactcgt atggaaaatc atcaaaaaac aaggcccact
     4441 caataagatg atctgttact gttcctcttt ttaaatgacg gattgccatg atctggtcaa
     4501 ttgtctgacc attcataaac atctgcttgg tgatcatcat gctttgattg aaattttgct
     4561 gtaataatga atcgatcaaa gcgtgccaaa gcgaatctgg ccgtttttcg atttgtgcta
     4621 acaaaaggtg gatacatctg ctttgttgca gataaaccgc tgactcatca ttgttttttg
     4681 ccagctgata aggaagcagc cctgttcgct catttccaga taattggtta gctaaaaaat
     4741 ctgctgcttc ttctggtatc tccgaaaaca gctgcaccaa actctcatac gcagtatcaa
     4801 tcaaaatttc acgtggcaat tggctttcac taagccattt ttttagttgg aaagtataaa
     4861 aaggacttgt ctctgctgga agatagtctt gaatacccgt tgccagatta gaaattactt
     4921 gaacagcaaa tttaatgagc cgccaactag tttcccctgt tctgccatag cggtcaaaac
     4981 gcaaaccagt atgttctatt tgatgttcgg acaacatatc agcccctgca ggcgttagct
     5041 ttgcttcatt ttcatttatt tcgatccaac cttgctgcgc aattttttgc aaaatttgat
     5101 aaaacttatc ctgcttcaat tctggaaaac tgttatggat aaacaaaagt tcgtgggtaa
     5161 atccataaat aagtactgaa gtcgttcgtt ttcccacaag gagttggtaa agagaactaa
     5221 tccgcagctt gtgtcctgat gaaaatagcg ataaaataaa aacaatcata ttattctcct
     5281 taagttagga tggttagaaa tgtcactact atgtaaactt gtacctgaac gctgtattgc
     5341 atgcggtctt tgtcaaatcg aagcgccaga tattttcgat tatgatgaag aaggaatcgt
     5401 tttatttgcc caagaaccag aggctcatca acagttcgtg atgccggaag aagaaacata
     5461 tgtaaaaaaa gcgtatcaaa aatgtccagt tcgagcgatt ttattagaaa ataaaatata
     5521 aatataaacg aaactttaaa aacgtacact aagttctcta aacttgaaaa taagccggga
     5581 tctgtttctc ttgttccgtg aaatcccgac ttattttgaa agattcattt gctatctata
     5641 gttaattgac tagttttttc acggacccta taggacccat ttatattatt tcaacttttt
     5701 cagccagttt tccaatgtat tgacgatcac agtttgctgg tctgcgttag aaatttctgc
     5761 ctctccatct cctttttgct caccatagct gccaaaacct ccatgatttc cgccattgat
     5821 tgatacatac tctgttcttt ccggtaaata ctgcttagct tcttgataag cttcctgatt
     5881 caatacttta tcttttgtcg ccgtgatcga taaaacagga acagctgatt ctgtcaatgt
     5941 tccttttttg tcgggataac ttgccatgaa gaatacccct tttaaatgtt tgtctgaatg
     6001 attcttattg acataacgac ttgccattac gccacctaat gaatggccac cgatcacata
     6061 atcggaattt ggaaaatctt ctttgacctt atccgctttg tttccgccca tcactgctag
     6121 atcaagtggc attttgacaa tagcgactga aaagccgttt tttgctaaat cttgcgccca
     6181 aatactataa ctttctggct ctacgagagc accaggataa aaaataagta atggagactt
     6241 tccatgattc tttttctctc cttcaaaaaa taagtaatct tctttgtttt ttccttcttt
     6301 taccaacact tgcgcttctg acgatggttc gtacgtattt tgctgtatat agtaataacc
     6361 ggctccaccg agtaatccta aaatgatgac taagccaatt agtattcgtc taaatatttt
     6421 cactttctcc caccttttct atctgagtga cccctttttc ttaatcaagt atgattatac
     6481 cttaaaaaaa taagagagaa atgcaaactt tccagcatca aataaaaaaa gacggaatat
     6541 ccatttgaat atccgccctt tttgtatgtt tatttttatt tagcacataa acgatacaca
     6601 gcttctgcat aaatttccat tgctttatac atactactta attcccatcg ttcattcgcc
     6661 tggtgcataa agtcaggagt atcagggaac atcgcaccga atgccacaca ctggttcatc
     6721 gtacgagcaa aagtagcgcc gcctgataca aacggttcag tcatgtctcc agtaatatcg
     6781 cgatatgtcc ccaatagatt tttcactaac tcactgtcta gtggcacgta taatgaatca
     6841 aggaagtcaa attcttcata agtcaaccca tatttttctg ctgttttagt taatttagct
     6901 actaaatcat ctttcttgaa tgtaacaggg attctcatat ctacaccgat ttttgtttgt
     6961 tctggtgtga tttccaaact tgcaaagttc atcgttagct cgccggattg ttcatcttct
     7021 gttttgccca cgacagcttc accagttgca ttttcttgaa ctaattttcc taagaaattg
     7081 attgggccaa aatcaaatac ttctgaaaga gcaattgcca gacgagaaat agcattcact
     7141 ccttgtgctg catctttcgc gtggatactt ttaccaagaa cgacgatgcc ttcaccttgt
     7201 tcttcgaaat cgaattcgtg ttttttcaat gcttctttta cttcagaaag cttttctcca
     7261 gagtaaggag ctgcatcagg aacaacattc aacgctcctc cagcttttac agaaaactcg
     7321 ttcgttcctg gtcctgtcaa gtaagcttgc aataagcctt tttctgcata aattaaagga
     7381 aattcagcat ctggcgcaaa tccttgcgta attccttctt ctttttcgtt atatttttct
     7441 aaacaacgcc ataaattttc ttcatctgta ccaaagataa aacgaatacg tgtcttgaat
     7501 tccacgccag catcaatcaa agctttgacg gcatacattg ccgcaataga aggacctttg
     7561 tcatcttggg atccgcgacc aactaaccag ccgtctttta tagttggatc gaatggtttt
     7621 gtttcccaat tattttcgtc ccctgctgga acaacgtcca tatgacacaa gataccgaat
     7681 aattcatctc cagagccaat ctctgaataa ccgtaatagc cttctggatc tttaaatgtt
     7741 ctaaatccta gcttttcact gatttccaat actttatcca aagcttcaat cactttttta
     7801 ccgaagggat gtccttgtcc tgaatctgct tcatctagta cggaaggaat tcggatcaat
     7861 tcgctcaatg attctaatgc ttgttcatga tgttgttctg tcacaaattt tttcatgata
     7921 ttatcctcct aatatgttaa aaagggtcat gtcaaattcc tccgacacaa cctcttcttc
     7981 tcaaataatg acgttttaag cctgctccat cagcaagcag aatgttctta acaaatgatg
     8041 aaagaaaaaa cactcactga atggagctat tgacttatcc acgtgcttat cgatagccgt
     8101 ttatcggttt cttcattctt atgatagacc ttgtacctgt atttgtctag gtttagaaca
     8161 ttgctgctac acctaggatc acacagatgg ctacaaataa tatcgcaatt aatttaccgg
     8221 taaatttcca ccacactgaa acatcgaaac gagcaattgc tacagcaccc attacgatag
     8281 cagatgttgg tgtaattaag tttactaaac cagatgcaga ttgataagca gtgattacta
     8341 aatccttacc gacgccggca aattcaccca taggtcccat gattcccatt gttgcagcag
     8401 ctaagccgga agttgaagga atcaagaatg acatagggat atagaaaata aatgtaataa
     8461 tgatgaatac acttgaagat aatgaactta atccttgttc gccccaatgt aagatggtgt
     8521 ctgtgattaa tccattgttc ataaccactt ggataccacg agcaacagct actacgattg
     8581 ctacaccgat caaatcagaa gcaccagcta aaaattcaga gacaaattca gactctttca
     8641 tgccataagt gattgctact acgatggaca ttactaagaa taacatagta atttctggga
     8701 agtaccagtc acctaatgga agcatgcttt tacctagaac cgtacctagt accggaaggt
     8761 ttgttaacca gtttgtcaat gattcaaaaa tcgtgaaatt cgcattcaag gttgtccaag
     8821 gaatcaaact gatgatcatg ataccaaaag taataaagaa caatacatta acatgttttt
     8881 gttttttcgt gattacttct tgacgaccga ttgcttcaat atcgaaatgc ttcatatctt
     8941 ctttacgttg gttgtatact aatgattttg ttggatcttt ttcgatcttt gatgcataac
     9001 gatacacata tacaatagaa atagctaaca aaataacgaa catcaagaat cgaagaccaa
     9061 taccttcacc catcgaaatc ccaacagctt gtgaagctac gcctgttgca aaaggattta
     9121 ccgttgaagc tagacagcct acttgagacc ctactaatac gattgctaca gctactactg
     9181 tatcaaagcc tacagccatc atgactggga tcagtaaagc atagaatgga atcgtttctt
     9241 ctgccattcc gtaagtagag ccgcctaatg caaataacag catcaatact ggaataagca
     9301 ttttttcttt tcctttgaat ttcttcacaa ctgaagcaat cccggcatct agtgcccctg
     9361 ttttgttgat aatacctaaa aatccaccaa caaccaaaat gaagaaagag attgggattg
     9421 cagcaggtgt ttctttagtt agctcccccg ctggtacacc tagcatccca ttgattggcg
     9481 ccatgaaaat atcccacagc ccttgaggat tttgttgtac tcgttcatat gatccagcga
     9541 cgatgttgcc tgcatcgtct acactatagt gcccagctgg tataaaccaa gtaagtacag
     9601 cgattactgc aataataata aataagaccg tatacgctga aggcatttga aattttttct
     9661 tttttgtttg ttccatcttc ttcttccttt cttttccgtt agagacaaca attttggctc
     9721 taatgttatt ttatcaaaaa gagtatcaga acaaaaataa taacacgcat tttgtaaaac
     9781 ttttgttcaa aaagttcgtt tttccctatt ccctcctctt ttttcaggtt tttaaagctt
     9841 tcttcttttt cattgtagcg tttccttttt tttataaaca aacattttcg tcttttaaaa
     9901 ggagaagaat ttcacatttg caaagaattg attgattttt atgcataaat caaaaaaata
     9961 ctcaaaacaa acaaataaaa cgtttacatt attgcatgtc ttgtattttt ttccaaaaaa
    10021 aaagaccaag aaatttcttg atctttttga tatttatttg actgctgtat gacgttgttc
    10081 gaactgatgt tgttttcgac ttaaccatgg aagaagttgc gcatgcagca ctaaaaagac
    10141 agcactcacg atgaatcctt tgatcaagtt gaaaggaacg atcccaatca gtacatagtt
    10201 tgctaaagac atgcccagca tctgtgttgc gttcagccct aaaaacatta agtaaagagg
    10261 cgtaataacg aaataatttg cgatactcat aaaaatagtt agagcgatgg ttcctgtaat
    10321 gacacctaaa aatttgtttc ttcctttatg ctgtttcttt acactaaaga aataataaat
    10381 cgggaatgta aagatcgttg ttgataagaa actagcagtg tctcctacca aattatccgg
    10441 agaaaaacct gtagtcagca gatgtaatac tgaacgcaag aacgctgttg caactccggc
    10501 cgctggaccg aataagaaca tgctgatcaa taccgagata tcactaaaat cgatcttcaa
    10561 aaaactaaaa gccggcatga tcggaaaagc aaaatactgt aaaactaatg cgatcgcagc
    10621 aaacatcgct actgcaacca ttttctgtac acgggtgttc ttcatttgaa atcctcctgt
    10681 taggactcct cttcagcgaa ctttttgacg tttctctcca aatgaaaaaa ctctattttc
    10741 cagggaaaat agagttagag ttatttgatc aagcgtcgtc aaataagctc tatcttcttt
    10801 atccagacta tactgtcggt atcggaattt caccgattca gctatttttt tgcaaaatag
    10861 gtcgtggact ataaccaccg gtcgggaatt tcaccctgcc cctgaagacg aaccttatat
    10921 aatttttgtt tacatattca ttatacatat ctattcaaaa aacgcaacat ctaacactta
    10981 taaaaagtaa gtgttcattt tgagtggttc agcaaactgc tgacttcttt tttgttcagt
    11041 tcacggtaat ccccaggacg taggccttgt aaagtcagat ctccgtattt ttcacgtttt
    11101 agtttttgca caggaagacc aactgcttga agcatatttt tcacttgatg attacgtcct
    11161 tcgtggatcg tcaattccac gatactgtgg tttgtcttag gatccactga taaaatttgg
    11221 aatttagctg gagatgtttt tcgtccttcg atctttattc cttttgtcaa aggtgcaagc
    11281 atcgattttg tagcgatccc ttttaccttt gcaacgtaaa ctttatccac ttcatgtttt
    11341 ggatgtgtca ggcgctgagc aaaatctcca tcatttgtca gtagcaagat ccccgaagta
    11401 tcgtaatcca gtcgacctac aggatagata cgttctttta ccatcggcaa aagatccgta
    11461 acaacttttc ttcctttgtc atctgcaaca gcagaaataa ctcctttagg tttgtacaat
    11521 aaatagtaac cgtattcttc ttgataaatt gggacttcat ccacttccac agtgtcatgt
    11581 ttcccaactt ttatccctaa ttcccttaca acttgtccgt ttacttttac acgtcctgca
    11641 aggatgaatt cttctgcttt tcgacgagaa gtgatgccag cgtgggcaat tactttctgc
    11701 aatctctcca ttacaattat tctcctttat tcattccatc aaagaataga tctggtgaca
    11761 cgtcttcttc aagtgaaatt tccatttctt gtgtatcagg cagttcttct aatgatttca
    11821 aaccaaaata atctaagaag tagccagttg ttccatataa tatcggccga cctggtcctt
    11881 ctactctacc tttttcttca atcagtttat gggcagctag acgctgtacc gctcctgaaa
    11941 cctgaactcc tcgaatctgc tcgatttcag ctcttgtgat tggctgttta taagcgatga
    12001 ttgctaaggt ttcgacggcg gcttgagata atgtgtttga tgtcccttgc gcatatcgct
    12061 taagtaaggg agccagctct tttttagtcg ttaatacata atggctttcc gtttcaaaaa
    12121 tatgcaaagc tgagtgcgag ttttgagtgt aagattcttt taattctttc actaaacttg
    12181 tgacttctgc ttcgctgaga tttaacagtc cgcttaattc ttcattactg atcccttcct
    12241 cgccaacaat aaaaagaagg gcttcaagtt cacttaattt cgtcatgttc ggtatctcct
    12301 actgctggat aaagcataat tgattcatag ttttcttttt gttgcgcaat gatctgccct
    12361 tttttcatca attctagcaa agccataaaa gtagtgacaa cttcactttt agaaggtgac
    12421 tcaaaaaaag aatcgaaagt acagccatgc gcatttcttt ttatacgctc ttcgataaat
    12481 accattcgtt cttcgatcgt tgtgtcatcg ggcgtgatcg ttttttccac tttttgagaa
    12541 aatttcttac gttctaagat tttctgcatg gcacggatca aatcgatttt tttgacttgt
    12601 cctcgcttca acggcttttc agcatccgct aacccatcga tgttcatagg ttcttttgtg
    12661 taataaagac ttcgttcctc tgctttttct gtcagtcttt cagctgcata tttatattta
    12721 cggtattcta aaagctgagt gaccaattct tctcgaggat cttcttccca taattcttca
    12781 tcgtctgtga cgaattcttg gacaggaagc aatgtcttgc ttttgattgc catcaatgta
    12841 gcagccatca ctaagtattc tcctgcaaca gctagctcga gtgttttcat tgtatggata
    12901 taattcatat attgctccgt gatcgtagcg atcggtatat catatatatc gatttccatt
    12961 tgctgaatca gatgaagcag cagatcgaga ggaccctcga atacatctaa tttaatattg
    13021 atctccgtca actcattcac tctttcttct ttttctttgc tagccatttt ccaatgtaag
    13081 gctctgtgat ttcagttgca cggatggaga catccgggta cttttcctgt aattcatcta
    13141 acatttgaaa gcccatattc tcaccgcgat aagacggatt caaagaaatg tcatggatga
    13201 tcagctgatc gttcgttgcc cagtaaatac caataatccc ttgaatgttg gttgaacctt
    13261 ctggcgtaaa gaaaaaaagt tcataatcgt cttcagattc gtacgtatca atctccttca
    13321 acaaagaagt tttacctgtc agtttcttat ggaaactcaa tagtcccata gcaattttac
    13381 ggttttcttt ccggtaatgt gttaacatct tctcaccttc ctatgactaa gcccttggaa
    13441 aatgctgctt ataaacatcc gtcattcttt tcttcgtgat atgtgtataa atctgagtcg
    13501 tagagatatc cgcgtgacct aacaattcct gtactgtccg caaatcagct ccattttcta
    13561 gcagatgtgt ggcaaagcta tgccgcagcg tatgtggtgt tacttctttg taaatcccag
    13621 cctctcgtac taactgcttc agatttttcc agattccttg ccgagaaaga cctttcccat
    13681 gattattgac aaatacatgc atttcagatg cgtcctttac aagtaatgga cgtgcttcgt
    13741 ctaagtagcg ttccagccat tggatcgcat aatcacctaa aggaatgatc cgctctttat
    13801 ctccttttcc aactgtctgt accagtccaa gagaaagatg aagatctccc aatttcaatc
    13861 caatcaattc actgacgcgc atcccagtag catacatgac ttccaagatt gcacgatctc
    13921 ttatccctaa cgtttttgtc gtatcaggtg cttcaatcag cttttctact tctgtcagag
    13981 tcaatgtact tggtaatttc tgtgctttct tcggcgtatc gatatgttgc atcggatcat
    14041 gatcagtgat acgctcttgc cgtaaaaact gatggaatct tctgagactt gagatcatcc
    14101 gagtaacagt tgctgtcgct tttttttctt catgcaactt ctccagaaaa cggatgacta
    14161 aaaagcgatc gacatcctgc catgaagcaa ttttctgctc ctgtagaaaa tgcaagtact
    14221 gttccaaatc acgttcatag ctttgtcgtg tattggcgga caatccccgt tcaatattca
    14281 agtagtggag ataatcgttg atttgctctt tcataataat ccccctcatg cctctctatc
    14341 atatcagata ccgcttcatt ctgatagtct ttttccataa tctgagcaaa gaaaaagccg
    14401 tctagacact cagacggact ggtttctttt ttctttttca tagcattcct gacagattcc
    14461 atggaacgtt agccgatgat cttttactaa aaaatgataa cgttcttcta ctacttgctc
    14521 cacttcaagt aaaagatcct cttctacttc ctcgatcgtg ccgcagttca agcatagtaa
    14581 atgatgatgg aaatgtttgg cgccttcttt tctcaaatca taacgggcta atccatcatt
    14641 aaaacttact ttatcgacaa ttttcaattc tgtcaagatt tcaagggttc gataaacagt
    14701 agcaagtcca atttccggac tctttttttt cactaaaaag aagatttctt ctgcagataa
    14761 atgctctttc tcattttcca aaagcacaag cagagtagct tctctttgcg gtgtcagctt
    14821 aaaccccgct tcatgtagct gctgttttgt ttttttcatc gccgaaatag cattcatgac
    14881 catttactca accccaacaa tttataataa ttacaaataa aaaaagatat aacactatgt
    14941 taattaaaat tattataagc tagttaagaa aaacatgcaa gggattctca attagatttt
    15001 ttgactagtt ttgtcacacc gttttcttgt gtaatcaatc cttgtttcaa aagattacct
    15061 aatgcgcgct taaatgctcc tttgctgata ccaaaagctt tcatgatttc ttctggatcc
    15121 gatttatctg taaagttgat ttgctgatct gcagaacgtt ctaaaatggt taaaatcatt
    15181 tgtgcatcat ctgatatagc ttcatatgct cttggcttca atgaaagatt cagtacaccg
    15241 tctggtcgga caccaatcac tcgacctttt atctgctcgc ctagacgagg ttcattatat
    15301 cgttcagaag gatggataaa cccaagatag aaatcttccg ttaaaacgta cgtacctgtt
    15361 aatttcaagc ggtatgctgt tcctatcaca tctttgtttt tcatttcttc tgttccatat
    15421 ttgcttaaag atttgaatat tttttcatct gctaaactgc cccaaatacg gtcttttgca
    15481 tcaactctaa gggaaatcat caagcgatcc ccttttttag gccatagctc tgtcattgtc
    15541 ggcaattcat caagagatac gacaaagtct ttatctggaa gaccgatatc gacaaacgca
    15601 cctaaatctt ttcgtgtagc agtaacgatt ccaaaagcgt aatgaccgat acggctttta
    15661 ggaatttgtg tagtgatccg attttcatgt ttttgatttt ggtaaccgaa tccttcaact
    15721 gcttcaccga ttttgtgttc accttctgat ttgcttaagc caaaggtttg tccgtttttt
    15781 tggacaaagt agtttttttc attttcatca ataataatac ctgtaaatat agttgctaat
    15841 aaatcgttca tttttttctc cctctatagt gaaaggtttt cttaatacat ttctttgcta
    15901 tcataacata atgttatcta cttgaatagc tgagccttgg tttggaaagg tgaaaaaagg
    15961 agtatgacaa cagttgtgtc atactcccct ttttcgaata aacggtgtta aacggcaggc
    16021 tcacagcctc tttcatttgc ctaaaattaa ttgctcccat ttcctccgaa ccatccagtt
    16081 ttacagttga tggttacgat gtaaaatggc aaagcacttt ctccaatgcc tttcatcaat
    16141 gcagattttg ttgaagtggc atatagatta taatagcctt ccccattttc gattctggct
    16201 ttttctaatc tgtaacctcc ttcaacgata tatccacgtt ggatacatgt agcaatcact
    16261 ttgctttgga cacctggtgc ccacgtccat gctggattag atgcatcggc aatatcactt
    16321 gctctggcag atttgattgg ctgattcgct gagtttgaag aggaaggggt cgaggatgcc
    16381 gcttcttgct gtgctgcttg tgcgaccgca gcttgttgag cggcttgagc tgcagctgct
    16441 gcttgagcgg cttgttttgc ttgttcttca gctgcttttt tcgcttcttc tgcttttttc
    16501 ttttcctctt cttctttttt ctctttatca gtgagcatct tatctacttg tttcaattgt
    16561 tcattcaact gagcagatag atctgtattt ttcacttttt ctactgcttc ttttgccgtc
    16621 ttgtattggt cgcgtgttgc tgaatccact acttttccgt ctttaaagac tatagctgtt
    16681 ttttctttag ctgtttgcaa ttcagcatat tgatttttag cttctgtttg tgcttgttga
    16741 atcaattttc caaaatctgt gttatccgtt tcgattgctt ggatctcttt atctgctttc
    16801 aacttgatgt catctgctag atgatcatcg acgatggcag gtgctatgaa ccactcattc
    16861 actttttgga tatctcggat cttagattgg atatcttggt aagttgtttc taactctgaa
    16921 tatccttttt cattcttaag actggataaa tcatttttta gttttgataa atcttgatga
    16981 atcatatctg cacgaataaa ttgatggtga tcatctgtat aaaaggcagc aagtttctca
    17041 tgaagttctt ccatttgttg ctgtcttttt gcttctgctg ctacttcggc ttctactttt
    17101 tgatgatggt cataataagc ccagcttcct ccaccgagta gaagtactgc tgctaaaacg
    17161 agataaggta ctttttttga ttttttcttt tgcgctttat ctggatctgt tttttctaag
    17221 tttgattctt gatgtgtttt ttcagtatct ggcacgattg ttattgattt cgcttctgct
    17281 tcaaacagct taggctggtt ctcttctttt tctatttttg cttcaagatc agtaccctct
    17341 ttgcttacag attgattttc agcatcggat tcactattta tttcatcggg ctctgttgac
    17401 tttttgtctg tgttttcgag tatttctttt ttctctgctt ccggcagttt attcgttttt
    17461 tccttttcta attgtttttc agtaaatact tcagtttttt ctgtgatatc cgtttttacg
    17521 tcttttattt ttactgtttc tttacctgtg gcgttttctc tatcagagtc tttttcagtt
    17581 tcttgttcct tttctggctc tactttgttt tcctgtgcaa ttttttcact gatcattttg
    17641 agcagctctt tcgcgtgctc ttcttttgta tcttcacgat gtgctttgat ataagcggat
    17701 agtatcgaat tttcttcctc attatcgacg atttctttca gttcagctac tcttcttttt
    17761 tgttttgatt caagcgtttc ttcttgattc tttcctgatt cttccgaagt ctcatgaaca
    17821 gttgctttct tctgttcatt tttctctata ttagttactt gatcgtgagc aggtggttct
    17881 tcgtcttctg gttctgcttt ttcgaataat tccattacag attctagagg taaatctttc
    17941 aattccgacc attcgattgg atcgtttaat tctgtatcag gaaagactgc atcttcagtt
    18001 gatttatcct gcatagctgc atctgtattt gtttcttcaa ttgattcttt tatttgctga
    18061 tcttctgcag ttatttgatg accgcagtct ggacagatag tattctgctc catttttttc
    18121 gatccgcaat ttggacattt tttcatcact tagcgatcgg ctcctttact aggtttacgc
    18181 taccatttaa tctatcatat tctatacgtc acgccaatag cttattttta ggatttactt
    18241 aaaaataatg aatgaatttc cttcctatag aaaaaaaagc ttgagactgc gtagtctcaa
    18301 gctttttttc ttttaaaata aaccaaacag ttttactgat ttctcttctg gtcaatagtc
    18361 cacgcttatt ctaagaaatc ttttaattgt tttgaacgag aaggatggcg caattttctt
    18421 aatgctttag cctcgatctg acgaatacgt tcccgagtaa caccaaatac tttccctact
    18481 tcttccaatg ttctcgtccg gccatcatct aaaccaaaac gtaagcgaag gacattctct
    18541 tcccgatcag tcaatgtatc tagtacatct tccaattgtt cttttagtaa ctcataagct
    18601 gcgtgttctg ctggacttgt tgcttcctgg tcttctatga aatcacctaa gtgagagtca
    18661 tcttcttcac cgattggcgt ttcaagggaa acaggttctt gcgcgatttt caagatttct
    18721 cggacttttt ctgttggaag atccatttcc gcaccgattt cttctggcgt aggttctctt
    18781 ccaaggtctt gcagcaattg acgttggata cgtatcaatt tattaattgt ttcaaccata
    18841 tgaactggaa tacggatcgt acgtgcttgg tcagcgattg ctcgagtgat ggcttgacga
    18901 atccaccatg tagcataggt tgaaaactta aatcctttgc ggtagtcaaa tttttcaact
    18961 gccttcatca gtcccatgtt tccttcttgg atcaagtcaa ggaactgcat gcctcgtcct
    19021 acataacgtt tagcgatact tactactaaa cgaaggtttg cttctgccag acgctgtttc
    19081 gcttcttggt cgccttcttc gattttcaat gctaacgcta cttcttcttc cgcagttaaa
    19141 agggagacac ggccaatttc tttcagatac atacgaaccg ggtcattgat ttttacaccg
    19201 gttggcgcag aaagatcttc tgtttttgct tgttcagctt ttttctcagc actcttcaag
    19261 ctgtgaattg atggatcacc attttcatcc accacactga tacctgcgtc ttcaatcttt
    19321 tggatcaatt tgtccatttc atctgcattc aaagtgaatg gtgtagcaag ctgattggat
    19381 aaatcatcat atacaacttg tcgtttgggt ttgttttctt tgatgaaagc tgctactgct
    19441 gcttcatacg tttttttatc tgttccattt gccataaaag aaggcccccc ttgagtagct
    19501 atttggcttg ttttaactgt ttcgttaaat tgatgatttc aatcgtcaat tcaagctcaa
    19561 gctgtttgtt tccagttcgt ctggcttctt gctgcatttg tttttttaat gttatttcat
    19621 cagctaagcc agatttgctg atcacatcta gcaagtcttg gatttctcgt ggcgaacttt
    19681 cttctgccac cggtaaatat tcgatttcca ccaccaaccg ccttaaattt tcatcttgca
    19741 aaaagtctaa aaactctgca aggttgaatt cataatgttg tgagacatat gcatcgaata
    19801 aaaaataaac ttctgcatat gcatcatgaa taaactgaaa ttctcgttct tttaaaatat
    19861 tacggacaga aacttcttta aatgcacgat ataatagaat ctgctctgcc ttttctactt
    19921 gcgtcaaagg tctctttttc cgtgcagttt cttgtctcgt aacctgagtg tgttgacttt
    19981 cctgaggttc ttgacgattt tgctgatttg tccttcgaag atcgcgcagt tgtttttgta
    20041 tcgtctctct gccgatctga aactctgttg acagttgaga tagatacata tcttgttcga
    20101 ttggtgaaac aactcggcta agttcaacta gtaattcttc gaggtattcg atcttgtctt
    20161 tttcattatc taaatttttc ccttgtttta aataacgtga tttaaaagta aagactgttt
    20221 cgcgcccatg agccactaat tcttggaaag atgcttctcc atacttacgg agatattcat
    20281 caggatcaag cttttctgga acgactacga cagaaagtgc taatcgactg ttttgccgaa
    20341 gcaattcaat ccctcgattg gttgcttcaa aacctgcgtt gtctccgtca tagcaaaaga
    20401 ccaattcttt cgtcagcttt tccatttgtt ggatctgttg agctgttaga cttgtcccca
    20461 tagaagctaa tccagttttg ataccagcct gccatgcagc aatcacatcc ataaaccctt
    20521 cgaacaacaa aatttctccg tttttccgga tatcgcttct tgctttatca agattaaata
    20581 aaacttgtct tttattgaac agttctgttt ctggactatt caagtatttg ggctgatctt
    20641 tttcctgccc tttttcaggt gcaagccagc gtcctgaaaa accgatcgtc tggccttgag
    20701 aattacgaag tggaaacatc actctttgat aaaaacgatc agacatacgg ccatcatcat
    20761 gcgtgacaaa caatccagag cgttctaaca attcatttga aattgattca ttcttgaata
    20821 cttgctgaag aaaagaacgc tcattaggtg caaaacctat gttgaattct tcaattaatt
    20881 ctaaagacaa cccacgactt tgcaaatatt ctaaagctgg ctgtccagct tttgtatgca
    20941 atagcatgtg atgatagatt tccgctgctt tttcatgagc agcaatcagt ttccccgtag
    21001 cagattcagg attttggaca gctatagtac gctgacgcca ttgatcttct aacggtatct
    21061 gttcgaagtc tgccactttt accactgctt ctggaaaact tagaccttct agttcttgaa
    21121 gaaaagtaaa cacgtttccg cctttaccac aaccaaagca atgaaaaatc tgcttgtctt
    21181 ctgcaacaga aaaagacggt gtacgttctt catgaaaagg acacagcccc aagtaatttt
    21241 taccagactt tttcaactgg acatattgtc caatcacctc aacgatattc gtttgactgc
    21301 gtactgtttc gataacctct tgaggaatcc gttgagccat tttttcaccc cctgctctat
    21361 tgatatcttt tgggtttaac agaagatatt tcaggagaat aaccggtaaa aaatcgcact
    21421 aactgaaatc agtgcgattt taaaggacac aattatacat gtttgattgt atcatatttc
    21481 attgcttttt caagtataac acatttctat ctcattaagc atcaatttgc tactcttttc
    21541 agtaactgat tttgaatatc agccttccag tacaatactc gaagaacaat atttacgagc
    21601 atgaatacaa agaagtatcc tacgctctct cccaacccta agtttacttc caaaattcca
    21661 tggaacagca ttgcagctac atatatccct acgatcgtcg ttactgctag gaagatgcgc
    21721 aatgggttga agggataaca agcttttaca actgccatgc aactgatccc aatcagcaag
    21781 taatacatca aagtagtagt ttcagcattt ccccatgcga atgtttttcc aagtagatac
    21841 accgcaatga tattcactac tacaagcaag gcatttggta aagcattaat aagtgctgta
    21901 ggcaaataac ggtaagtgat ttttctttta tcttgttcaa aagataaaaa gaaggaagga
    21961 tacccttcaa tcgctaaatc aatcagcgtg atttggatag ggataaacgg aaatccaatt
    22021 gctgtaacgg cacatataat cgataaaata aatgaataaa tcgttttgat aaaaaagatg
    22081 cctgagactt tcgtcacatt gttgaccact cggcgtcctt caaacaggac ttctggcaat
    22141 gtagtaaaat cagagtccaa caataccaga ttcgcaatct gacgtgttgc tccatcacct
    22201 tctgccatag caatgctgca atctgcttct cttaacgcca aaacatcatt cacaccgtcg
    22261 cctgtcattg caaccgttct gccgctttct ttcaattcat ttaccagcaa tttcttttgc
    22321 tgcggactca ctcgtccaaa aaccgtatag cgatgagcag cttctcgcac ttccatttct
    22381 tcagtaattt gagaaagatc gacatacgca tcataattcg gtaatcctgc acgtctagcg
    22441 atattggaga cagtaaaagg attgtctcca gaaatcactt tcagatccac accttcctca
    22501 tgaagataag ctagtgtttc ttgagcgttt tttcggattg gatcatcgat ttcaaacaga
    22561 gcaaccggct caacaaatgc tggtttttct tcgttcaatt gctgatttgg agcgatcccc
    22621 aacataagta cgcgatagcc attcgcttgg gctgttttta gactgtccgg aagccgatct
    22681 tcttccacca aacgttcagg cgctcctacg tacacgactc ccagttctgg aaattccatc
    22741 gcgccccatt tgcgatcaga agaaaatgcg actttgtttg tcacatcata ccgattagaa
    22801 agctcaaaat aatctctcat agcccgcata gtgatgttgt tatcactgct ttctgccaga
    22861 tacgtcccca taatttctgg gatggctttc tcgtacagcg gatgtagtgc ttctacccgc
    22921 tggatactca ttttcccttc agtaatggtc cctgttttat ccaagcataa tgtatcgaca
    22981 tgggccagcg tttcaattga atacatgtct tgaacaagga ttcgtttttt tgccagtttg
    23041 gttacccctg tcgttaatgc aatacttatt agcaatacca aaccctttgg aagcatgcct
    23101 aacaaagctg ctgcagatgc aataacagaa attttgatag aagcatcgcg gatgaacagt
    23161 gcttccaaaa atagtatgat ccccaaagga ataatcacga aactagtgaa tttggatact
    23221 ttgcgaatcg aatctacaag ttcagaacga atagctttgt gagtctttgc ctcgctagtc
    23281 aagcggacag cataattatc tgcacctact cggataactt cagccatgac agaaccgctt
    23341 gtcaaaaagc ttccagaaag caattcagct ccagtttctt tgacaatcaa atcagattcg
    23401 cctgtcaaaa gagcttcatt tgcttctgcc cgtccagata taacctgtaa atcggctggt
    23461 atctgttctc ctgctccgat ttttaccaaa tctcctaata ccagctcttt agtagaaatc
    23521 gattgttctt taccgtcccg gatcactagt acttctgatt gggaaacaat cgataatttc
    23581 cgtacaagat ttcttgcatg tatttcttga taaattccaa taacgatatt gacgacaata
    23641 attgctaaat acgccatgtt ggaatacgca cctacaaata acagacaaat cccaatacca
    23701 aagttcagaa aattgaataa cgtcaatata ttatcgctga atatttgttt tgtacttttt
    23761 gatgcatctt cctggtagtc attttgctgg ccagaagcca ttttctgaac tacctcttgc
    23821 tgtgtaagtc cattcatttt ctttttctcc attttccgcc aactttcaaa aataatcacg
    23881 tgtttaagtc tagcgtgttc caagattaaa aacaacttgt ttttataaaa tttatagaaa
    23941 aacacacgaa tgattttaca aaaaagatgc caaccttttt gtttgaatca cccgtgtgct
    24001 gtttttatta tcaatctatc tttacttata ttgttcctcc aaacggctca tccaccaacc
    24061 tagtgctgta ccggctataa aaagaacagg acaagctagt accccagcaa ctcccaatcc
    24121 cgcgtaatcg gtaggaatga tcataatcgt tgaagcaaaa actacaccta aaatgaaatg
    24181 gaatagcttg ctatatgcct ttgagaaaat gtaatccatg atttttgaca atccaagaac
    24241 acaaagaatc ccaccaattc cgatcggcac aatcacttca agtcgtactt ctttaaatcc
    24301 gtcagccatc gctttataca atcccatata caccaaaaaa ttagaagggc tcaatcctgg
    24361 gacgatcata cccaaaccaa tcaatccgcc ggcaatcagc catgttccaa aattctgatc
    24421 gacttgcccg tcaaataatt gagcgccgta taataaaaac aaataagcca gaacaaaagt
    24481 aacaaccatg atgatcacat cagaagtatc tcttcctttt ttccctgctt ctttccataa
    24541 cgcaggaaca gttccagcga tacatccgac aaaaaaccat aatatcgttg tttcatacgc
    24601 acctaataaa aaactgacta aaaaagaaag tagaaagatg cctgtcactc cgcctagacc
    24661 aacaggcaga aaaaacaaaa cattttcttt gaaatttttt gtaaggtggg ctaaaaaaga
    24721 aatcagccgc tcatacatgc caaagacagc tgctaatgca ccaccgctga ctcctggcaa
    24781 gataaatcct gaaccgataa acattccctt cacaaaccgt aacatccagt ctttggttgt
    24841 gtaccccact tcttgatttt ccattttttg ccttttttcc actatttgcg tactccttct
    24901 ttcatttaat tttattcatg attgaacatt tcctgctatt ttacttaaag actttttcat
    24961 aggtctctat tattttttca ttcattttga caatatcagg ataaaacatg ttacctccat
    25021 tatgatagag atagccgcca ttgtaaagca aggactggat ccgccaatat cggtattgtt
    25081 tcccttcctc atttcctaaa agtgggctca gcacatcttt agaatacgct tctgctaatt
    25141 ctactgtgtt ttctccgcca tgatttttta cataggcaat ataatctttc ccaaaattat
    25201 atgcttggac agctgtccat aaatcgcatc cttgtttctt tgcttctact atcatttccg
    25261 ccaaatattt gacaccttga tcaatactgt cagctggatt atcaatgatc tcagcttctc
    25321 catgcagact ttccgagctc tgcatgagat ctgtcccttt tccttttgat tcggtcaata
    25381 ttatcgcctt gatcaaattc tcgtagtttt ccatatgata attttttgca gctgttgtta
    25441 tttctatttg atagctttcc actcgtttta ccgaacgata agttcttcct cataaaaaca
    25501 acaccgcacc aataaccgtc agaatgatca tgtaaaaaag aatacggata atagataatc
    25561 gttttcgctt catttcatca cctagttatt ttgacatctt tttttatctt actatttctt
    25621 tatcttcttg gctatttctt ccttgatttc tgtgtacgcc ttaagaaaaa atgaattttc
    25681 ctgtattttt tgacatctta cgaaaatgat cgttgttttt cagtaaaaac aattgcccaa
    25741 tgactgatat aatcgttata ctttacacag taggtgatta tgtgaaaaaa gaaaagaaat
    25801 atgcaaaaat gccagatggg agcgaaattt actatgaaaa gagcggtcaa ggcttccctc
    25861 tctttttact gcatggcaat gacggcagcg gccgcttttt ttcagaacag gtccctgtac
    25921 tcgaacgcta ctataccgtg tatctagtag atagccgagg acatggtcgt tcgacaaacg
    25981 aagcatctat gttgaatttt cagttaatgg ccgaggatct gaatacgatc atgttgctgg
    26041 aaaaaatcga tcaggcagat tttcttggat ttagtgatgg agcaaatcta gcactggtat
    26101 ttgccagcag cttccctaaa aaagttcatc gattgatttt aaattctgga aacacgcttg
    26161 ttaaaggcgt tcgtttttct gccagagtca tcagtaatat tcattatgca tgggtatggt
    26221 tactctcttt atttcgccca agtcttcgca aaaatctttt agttatcaaa cttttgctgc
    26281 atgacatcgg gcttacagaa aatgatttaa aaaaaatcaa ctcccccact ttgatcatcg
    26341 tgggaaaaaa agatgtaatc aagctaaaac attctttgta tatagctaaa actataccaa
    26401 aagcttcctt tgtgcttgtg aaagaacaag gacatgaatt agctagaaaa gatcctgaac
    26461 gcttcaatcg agaagttctt caatttcttt ctgaaacata actattagga atagaaggtg
    26521 atttatttgt taaaaaatac catacaatgg ctgaaaaacc acctaggact gttcaaaaca
    26581 atctttttga tttctgtcat tgtcattatt gtcggtgaat tgatgtccat cggtaaaact
    26641 ctatctatcc agcaattagg agaaacgttt gccactatac ctgtatggaa aagcggacta
    26701 atgctattga ttggtcttat ctctgtgtta cctatggttg gttatgatat tattttgaat
    26761 cggatgcttg aacaaaagca gaatcctcgt tacctgtttg agacaagctg gctgatcaat
    26821 acgatcaaca atattgccgg tttcggcggg tttgttagtg tggggcttcg ctctgaacta
    26881 tatggacaaa agaaagagag cagaaacgtg atccaagcat tatcgaaagt tttcttgttt
    26941 ttgatggctg gactttctat ttacagtctg ctttcttttt tacttgtagt cttcacgcca
    27001 gttgctcctt ttttgaagca atattggata tggttgatcg gcggcggtct atattttcct
    27061 gtcgtctttt tatttactac tttcaaaaag aaaggattcc ttggtggtac ctcacttaaa
    27121 actcaaggac agctattgct agtttcattg ttggaatgga ccggtgtcct gtttagtttc
    27181 ctttctgttg gttatttaat ggaaatccgg attgatctgt ggcaaacaat tccattattc
    27241 attgctgctt cagtgatagg aatcgtgtct atgattccag gagaaattgg gagtttcgat
    27301 gtaatgatga ttatcgggtt gtccgctatt ggtgtgccaa gagaaatagt cgttgtgtgg
    27361 atcttgctct atcgcctgtt ctactacatc attccgtttt tgattggaat cgtctttttc
    27421 ttcaaaaata tcggttccac ttttgatcag cgttattctg gtatccctaa acaattagca
    27481 acagaaattg cgcataaaat cgtggttgtc ttattatact tttctggaat catgctagta
    27541 ctttctgcca ctatcccgca agcttttaca gagtttcgct ggcttcatag tttgaaccca
    27601 ttgaaatttc attttattat ccaatttcct agtatactat tgggatttct tttaatcatt
    27661 atgggcagag ggatcgcagc acgtgtgaaa cgagcatatt tgcctacaat cttcttgatt
    27721 gttctagctt tactttatgt tttattaagt gattttagtt tcacaccggt ggttttcttg
    27781 tctattctgc ttctgatcat tcttgcttct aaaaacgaat tatttcggga acaattgatc
    27841 tattcatggg agtggcgtac gatcgatgga atcattattg gtgcactgtc cttgctttac
    27901 atcgttattg gggtatacaa tctgccggat ttccctcatc ggcgtcacca ttttatttcc
    27961 tttttcttat ttccttctga aaagatttgg ttttcgggat tgttggccat catcgctgtt
    28021 agtttcatga tcgttctatt tgttcatttc cttcaaggag aaaagaaaca gattggcgaa
    28081 gcctttaatg aagaaaaggc cctgaagatc cttacaactt atggaggaaa ctccgatagt
    28141 caattgatct tcttaaaaga taagcggatg tttgcctatg aaaaagacgg tgaaccaact
    28201 gttcttctcc aattcgcttg cttcaataat aaatgtattg taatgggtga tccttctggt
    28261 aagaaagaag attttccaga agcaatcgaa gcttttatcg aagaaacaga tcgactatgc
    28321 tatttaccag ttttctacga aacaagcgaa gagattgtta tgattttgca tgaattcggc
    28381 tacgatttca ttaagatggg ggaagaagct tatgtagacc tgaatagttt tacaacttca
    28441 gggaaaaaaa tgaagggcac tcgtgctgtc ttgaatcgga tcgaacgaga aggatttaca
    28501 tttgatgtct tacaaccacc attttctact gagcaaatga gtactttcaa aaatatctct
    28561 gataattggt tgggttcacg aaaggaaaaa gggttttctt taggcttttt ctctgaagat
    28621 tatctacaaa gagcgcctat tgcagttgtc aaaaataccc aagaagaaat tgtcgctttt
    28681 gcaacgatca tgcctactta cacgaacaat aaagtaggaa cgattgatct gatgcgatat
    28741 gattctaaaa aagcaccttc tggcagtatg gatttcttgt tcttgcattt gtttgcctat
    28801 atgaaagaag aacatatcca atggttcaat ttagggatgg cccctctttc aaatgtcgga
    28861 acttccagaa agagtttttt acaggaaagg attgcatact tggtttacga gtttggttct
    28921 catttttatt ctttccatgg attaagagaa tataaaagca agtacgctac aaactgggtc
    28981 tcacgttata ctctatattc tagagatagt tggattgcat atgttatgat tgctttgctg
    29041 attattgata atgcgccagt tgagcagaca caaggtagaa taagtggttt gaaaaaatgg
    29101 atacgaagaa agtattaaaa actgcatacc gatagatgaa cactctcatg atgaataaaa
    29161 gagactgaag taaaacgaaa gttcatgctt ctacaatctc ttcttataca attgaagaac
    29221 aaagagcggt ccaaacagaa atcctgtttg gaccgctctt ttattttaaa catttttcat
    29281 taccaaaata ttcgagtcgc gtttcttatg cttcgatctc tgtaacgata cctgaaccta
    29341 ctgtccgtcc gccttcacga attgagaatg tcgttccgtt ttcaacagcg attggatgga
    29401 tcaagtcaac atcaatcgtc acgttgtcac caggcatgac catttctgta tcttctggca
    29461 atgtgattgt tcctgtaaca tcagttgtgc ggaagtagaa ctgtggacga tagttgttga
    29521 agaatggagt atgacgtcca ccttcttctt ttgtcaacac gtacacttct gctttgaatt
    29581 ttgtatgtgg agtaatggaa cctggtttag caagtacttg tccacgttcg atatcgtcac
    29641 gttggatccc ccgtaacaac acgcctacgt tatccccagc ttccccgtaa tctaacgttt
    29701 tacggaacat ttctacacct gttacaactg ctttttgtgt ttcaggtttg atccctacga
    29761 tctctacctc atcaccgaca cgaacagcac cacgatcaat acgacctgag gcaacagttc
    29821 ctcgacctgt aattgagaag acgtcttcca ctggcaatag taatggttta tctgtatcac
    29881 gttctggtgt tgggatatat tcatctactg tatccatcaa ttccataata gcagcttcag
    29941 catctggatc gccttgcaat gcttttaatg cggaaccttt gatcacagga gtgtcatcgc
    30001 ctgggaaacc atattcgctc aataactcgc gaacttccat ttctaccaaa tcgatcaatt
    30061 cttcatcatc gactaaatca actttgttca agaaaacaat caggtatttt acaccaactt
    30121 ggcgtgacaa taaaatgtgt tcacgtgttt gaggcatcgg accgtcagtt gcagaaacaa
    30181 ctaagattgc accatccatt tgtgctgccc ctgtaatcat gtttttcaca tagtccgcgt
    30241 gtcctggtgc atcaatatgc gcgtagtggc gtttttctgt ttcatattct acgtgtgcgg
    30301 tattgatcgt aatcccacgt tcacgttctt ctggagctgc atcaatacta gcatagtctt
    30361 gaggatttgc taggcctttt ttgcctaata ctgtagtgat cgcagcagtt aaagtagttt
    30421 tcccatggtc aacgtgtcca atcgtaccaa tgttaacgtg tggtttactt ctgtcataat
    30481 gttcttttgc cataatttac aaacctccta aataatatag atcactgaaa aatttcagct
    30541 ctcacctttt tattatagtc tttttttgac taaatcaaaa agaatacgtc cgacttactt
    30601 tttgtaagat tcgaactaag cttattatac gtcaatattg gtcaaagtca actaagagca
    30661 ctcgtctgtc ttatacgcga aaaaagtacc ttttataaat aaaaaaatgt gttttttgag
    30721 aaaaacttca agatagtcct taactttctt ttgaagcaat aagaacaaaa tgaggaaaag
    30781 tttaaaattc agctgttgcc aacaactttc aatagacgaa atcttctatt tcgttaataa
    30841 taaggaaaga ggtgaagtac atgaaaaaat taattggcgt acttgtcgtt ttaggcatat
    30901 ttctcggcgg aagttttgca gcttatcatt atttttacgg cggcgaagct tattatacaa
    30961 aaatcacgac gaatggcgaa atgtcagcta cccaagcaga taacggagag aaattcacga
    31021 cttataccta caagcaagcg gcttataata aagatggtga aaaaaaacag gtgacgcttc
    31081 gcgaagaaag agaacatcca ttaaagatga atgcgtatct taaactcaaa gtcaatcctc
    31141 gtaaaggtgt attaagctgg gaagaaataa aggcttctga agtgcctaaa aatgcggcag
    31201 aaaaaatcga taattagtaa atggtcttaa aattttatta gataaaaaga ggctgggaca
    31261 gaagcgttta actccaagaa ataagaagga gttgcttctg cttccgccgt ttatacgtgt
    31321 ttagagcgtg agacaaaagt gttctttact tttgtctcac gctctttttt tgttatattc
    31381 gtcttttccg atccttctct tgacacaatt catttaactg atcactggta cttgaacacc
    31441 taatattcta gtcattttta taaacgattc aatacttcat ccacattttt gatcatcacg
    31501 gatatcgtac catccggatt attcacaaat tcaatcaaat ctgggttgcg atatacatct
    31561 actggtacga tcagttcgat cccgtttgat agcttgaatt tttgttttcc aaattttttc
    31621 tcagaaattt cttgtacttc ttttacagga ggtgcttctg ggacaaatcc ttgctcttgt
    31681 acttcttctt taaaagccat ttttgccgtg atgttttcct tgaagacttt ttccgcaatc
    31741 atctcatgat ccaaccgacc tttttcttct atcgtatcat agacagcttc tttcaaatca
    31801 gccatgatat caaattcttc tgtctcaaat ttttttccaa gatgcttggc tactttttgg
    31861 atcactttta cattttcttc taaagaaggt gcaggaacac tttcgatcac tcttccagaa
    31921 aaataaagct cttttttgcc agaaaactca tatttttttt caattaattc gtaggtccaa
    31981 tcagtcaaat tcacagcgaa tgcttcatct gctttttgtg ttttcgcccc tagaattgct
    32041 cgattcaaaa tcaagcggtt gtcgatccct gcttcgtctg cttcaacaaa gtgagtgtaa
    32101 gcctcacgat aattgacttt caataaagat aagtacatca ctgtatctaa ttcatacaag
    32161 acaacaaata catctgcact aggtgcttct tcactttctt ggtagatatc gaaccaccgc
    32221 tgaacgattg cttcacttgc ttccacaaaa ttttcttgag cgattttaag tgattcaacg
    32281 atcatgcttt cttctgctag ttgtccagtt tttgtttgag cagaagagat tttttggatc
    32341 ttcttttgaa gaaaatcacg aatatattct tttgtcagat ccagctcttt ttgtgaaaag
    32401 actggagaac cagtttctct gtcaataata tgcagaattg ctttttttaa atagatatcc
    32461 attttctcat tcccttctgt cttagtttac ggaaaaaaaa tcaaaaatac cagaatcaaa
    32521 atcattttct tttaaacaaa aatttcaaga gtagaaacaa aatggattct ttttttcgaa
    32581 aaatgcgcta cacttatagt tgaacgaata aaaaaggagc tgaaagtatg aattcattaa
    32641 caagcactta tcgtctatca aatggttacg aaatcccggt agtaggattc ggcacatggc
    32701 aaacacctga tggggatgtc gctgtttcct ctgttaaaga agcgctggct gcaggttatc
    32761 gccatatcga tactgcccaa ggatacaaga atgaagaaag cgtcggccaa gcgattaagg
    32821 aaagtggaat tcctagagaa gagatattct tgacaacaaa attatggaat gcaaaccaca
    32881 gctatgaact tgtgatgtct tcttttgaag aatcattgaa gaagctccaa acagattatt
    32941 tagatctgtt tttgatccac tggccaaacc ctgttgcttt tcgtgataat tgggaacaag
    33001 caaatgcaga tacatggcga gcatttgaag aactgtatga agcaggtaaa atcaaagcaa
    33061 tcggtgtgag caatttctta ccccaccatc tagatacact agcaaaaaca gcaaaaatta
    33121 tgccgatggt caatcaagtt ttccttgcac caggcgaatt acagacaact gtagttgagt
    33181 atgcaaaaaa acatgatatg atcctcgaag catatagtcc attaggcact ggtaaaatct
    33241 tcgatgtgcc tgaaatgaaa caaatcgctg aagcacatga caagacgatt gcacaagttg
    33301 ctttgcgttg gtcgctgcaa cacgaattcc ttcctcttcc taagtcagtg acaccaagca
    33361 gaatcaaaga aaatactgaa ttatttgatt ttgaattaac agaagaagaa atgaaacaaa
    33421 tcgatcagtt agatggtgta gtcggcaaag caaaagaccc agatactacc caattttaag
    33481 tcgaaaggtg attttatgga tccaatcgaa cgcttgaatt ctctctcgga agaagttacc
    33541 cagacttttc attccgattt tgtctttttg atcgatgcag agaaaatcca acattttcct
    33601 gcaagaaact ggacacatga tcaaatcatc gaagaactga aaaaacggtt cgatcattcg
    33661 ctaatggtca aaccctggca cgaacatgaa gtcatttatt cacctgaact acctgttttt
    33721 gccttgatac cgaaaaaata gaaagaatgg aacggattat gtatatatac ataatccgtt
    33781 ccatttttta tttttctttc aaaaaacggg aaaatacgca aatttttctg ttgtaatttg
    33841 cgtatacgca agtttttttg cattactcct tttcatttgg ctgttttttt cttataatcg
    33901 aaagggtatg agcgaaggag agaacatatg aagaaaaaac agaaacaaaa attattaaat
    33961 caattccgtc cttcattgga tggtgtaaga ggacaattat tccgttctct agaagaagag
    34021 agcttgcgac gttatggttt gccgttacaa gtcatgcttg atcccaaaaa ccgtcaaatc
    34081 ttaacgatcg gattagctgg gaaaacaaat gaagatacac ggatcaacgt gccaatcgat
    34141 gacaacttca atactgtatt aaagagaatt cgttcaggag aaaacgggat tttcgaacga
    34201 ttccgtgaca atcttcttat tgaaatcgtg tcttactgga atgatcaacg attgaaaaac
    34261 gatgaaccaa ctgcgcaagc tgttgcgaca ccagttacag aagaaacagt cagtgtgcca
    34321 gaagaaaaaa cggaaaaacc aaaagcggac acaactgaaa atacacgctc aactgatacg
    34381 aatgccgctt taagttttgc tgatttttca aaagccgttg ctgagtatcc taaattttac
    34441 acagaacaaa atgaacatga agtagttatt aatgaaaaaa atgctgatga acctcgtaaa
    34501 ttagcaacta tttctatgac tactgaaaat gagttcgtta tcgaaaaagc actcgaacgg
    34561 aaatacaaag tcaaattgac tttgattcct ttgatcgaac aatttgcagc gacagcgatt
    34621 actgatcgat aaaaattcta tttgtcataa aaggctggga tttaaaatcc cagccttttt
    34681 agtcatataa taatttctac agcaagtaaa aagaaattcc ttctaacatc aggctcaaat
    34741 atcagcttga cctgtccaac aaatcaccta tgatcctaca atgttaggcg acttctcttc
    34801 tacctgaaga tatcttggag ttgcctgatt tcttaagatg cctaacctta actataaaaa
    34861 attctaataa taaacatatt ttctgataga gaaaaaa
//
LOCUS       DACCVZ010000023        34652 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.023, whole genome shotgun sequence.
ACCESSION   DACCVZ010000023 DACCVZ010000000
VERSION     DACCVZ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.023"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(60..1613)
                     /locus_tag="IVW63_001125"
     CDS             complement(60..1613)
                     /locus_tag="IVW63_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7859412.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            1761..3050
                     /locus_tag="IVW63_001126"
     CDS             1761..3050
                     /locus_tag="IVW63_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP7859413.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEVAPEEKPDVTP
                     EPDTDSGNQTVPETNPDTDNETENPEKLEVDPEEKPDVTPEPDTDARDQGIPEKINKK
                     TIQEDGKKESKKSNLAILKINEEQLNKKSRIFDSAQSAETLKSSKDTTFASPETKNKQ
                     LPKSGESQNKVILWSGIILLSIATMLSAKRFKQNRSL"
     gene            complement(3176..4255)
                     /locus_tag="IVW63_001127"
     CDS             complement(3176..4255)
                     /locus_tag="IVW63_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP7859414.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVIALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(4364..4804)
                     /locus_tag="IVW63_001128"
     CDS             complement(4364..4804)
                     /locus_tag="IVW63_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7859415.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(4861..5271)
                     /locus_tag="IVW63_001129"
     CDS             complement(4861..5271)
                     /locus_tag="IVW63_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAP7859416.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(5452..5886)
                     /locus_tag="IVW63_001130"
     CDS             complement(5452..5886)
                     /locus_tag="IVW63_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP7859417.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(5986..6834)
                     /locus_tag="IVW63_001131"
     CDS             complement(5986..6834)
                     /locus_tag="IVW63_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP7859418.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            7223..8989
                     /locus_tag="IVW63_001132"
     CDS             7223..8989
                     /locus_tag="IVW63_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAP7859419.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            9091..10350
                     /locus_tag="IVW63_001133"
     CDS             9091..10350
                     /locus_tag="IVW63_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP7859420.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            10497..11798
                     /locus_tag="IVW63_001134"
     CDS             10497..11798
                     /locus_tag="IVW63_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7859421.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            11801..12652
                     /locus_tag="IVW63_001135"
     CDS             11801..12652
                     /locus_tag="IVW63_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7859422.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            12665..13480
                     /locus_tag="IVW63_001136"
     CDS             12665..13480
                     /locus_tag="IVW63_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAP7859423.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            13631..14797
                     /locus_tag="IVW63_001137"
     CDS             13631..14797
                     /locus_tag="IVW63_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7859424.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            15027..15674
                     /locus_tag="IVW63_001138"
     CDS             15027..15674
                     /locus_tag="IVW63_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAP7859425.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            15758..16702
                     /locus_tag="IVW63_001139"
     CDS             15758..16702
                     /locus_tag="IVW63_001139"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HAP7859426.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            16837..18288
                     /locus_tag="IVW63_001140"
     CDS             16837..18288
                     /locus_tag="IVW63_001140"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAP7859427.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            18309..19145
                     /locus_tag="IVW63_001141"
     CDS             18309..19145
                     /locus_tag="IVW63_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAP7859428.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            19145..19804
                     /locus_tag="IVW63_001142"
     CDS             19145..19804
                     /locus_tag="IVW63_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP7859429.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            19930..20619
                     /locus_tag="IVW63_001143"
     CDS             19930..20619
                     /locus_tag="IVW63_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859430.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            20625..21581
                     /locus_tag="IVW63_001144"
     CDS             20625..21581
                     /locus_tag="IVW63_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HAP7859431.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            21625..22137
                     /locus_tag="IVW63_001145"
     CDS             21625..22137
                     /locus_tag="IVW63_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7859432.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(22393..22941)
                     /locus_tag="IVW63_001146"
     CDS             complement(22393..22941)
                     /locus_tag="IVW63_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7859433.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(23030..24211)
                     /locus_tag="IVW63_001147"
     CDS             complement(23030..24211)
                     /locus_tag="IVW63_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAP7859434.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(24447..25955)
                     /locus_tag="IVW63_001148"
     CDS             complement(24447..25955)
                     /locus_tag="IVW63_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAP7859435.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            26114..26305
                     /locus_tag="IVW63_001149"
     CDS             26114..26305
                     /locus_tag="IVW63_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859436.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            26508..27425
                     /locus_tag="IVW63_001150"
     CDS             26508..27425
                     /locus_tag="IVW63_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HAP7859437.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            27418..28491
                     /locus_tag="IVW63_001151"
     CDS             27418..28491
                     /locus_tag="IVW63_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859438.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            28639..29157
                     /locus_tag="IVW63_001152"
     CDS             28639..29157
                     /locus_tag="IVW63_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859439.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            29138..29530
                     /locus_tag="IVW63_001153"
     CDS             29138..29530
                     /locus_tag="IVW63_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HAP7859440.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            29606..30541
                     /locus_tag="IVW63_001154"
     CDS             29606..30541
                     /locus_tag="IVW63_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HAP7859441.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            30674..31453
                     /locus_tag="IVW63_001155"
     CDS             30674..31453
                     /locus_tag="IVW63_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAP7859442.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            31446..31763
                     /locus_tag="IVW63_001156"
     CDS             31446..31763
                     /locus_tag="IVW63_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAP7859443.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            32007..33617
                     /locus_tag="IVW63_001157"
     CDS             32007..33617
                     /locus_tag="IVW63_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP7859444.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            33774..34622
                     /locus_tag="IVW63_001158"
     CDS             33774..34622
                     /locus_tag="IVW63_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP7859445.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        11455 a         6166 c         6707 g        10324 t
ORIGIN      
        1 cttgatacat aaatccggag gttgttaata agcattcgga tttatgtatc ttatttggtc
       61 taggaagtaa cttgattttc ttttttcgat tgatccatga gtgcttcttc ttttaattca
      121 aagatatatt ctgagatcct cataatcact tttttccagt cttctggtgt gatgattcct
      181 tttaaaatat agattttttt gatatgagaa ggcaattgtt tcaaagggca gtcgctgata
      241 acgatgttgc agttctccat aaaatcattt tgtattttga tcgattcatt tgaaaaaatt
      301 tgttctatct taacgatcag atctttactg atataaaaat cacgcgtata gttcacacca
      361 atcacaattc gcggctgttt tttgtagcga tcatacaaat gtactaggtc ttcaaccatc
      421 cattgcacat tttccttttc taaaataact ggtaacaagt gttgattttg ttctctgaaa
      481 tccatataaa attgttcaat ggcggtttgg acttctttca acacgctatg ttcttgataa
      541 agcatgaaag taggaagggg cgtatttggt tgattgaagt taagaaatcc attataaagt
      601 ttatttcgtg cgaatgccaa tgagtaaaga atcttttctt tttcaggtat aaacaaatca
      661 aatacagtac aaaaggactc caccatttct cttgaataaa gaacatgagg aacgtttgct
      721 ttttttaaaa gtttgtattg ctccaagctt gtttcttccg attcgatttt cgtgatagaa
      781 agtcgagcta aaatattcac taagatgcgt tgttcgcgac aaattggcag attaggtcgc
      841 aaaatatcta cagagggatc aataaaaaag tcaatatatt catactctgt gaattctttt
      901 tgtacgtctt tcacagaagt tgcaggaaaa ttctctttac atatttttaa tagaaaatat
      961 aatttatcta tcataccgct atttagtcgg tcaagtactt cttttttaaa aaaagtattc
     1021 atcataaaag ccactacttg cggatcttca tcataaaatt ctgtagcagt acttgaaaag
     1081 atgttccaat aaatatctaa tgctgcatat tgaatttgta cctcttttcc agaaaaagac
     1141 tttctgccat tattagaaaa ggagatagac aaaccgtaca atgctaaaaa tgcattaatc
     1201 tttttcattt tcgtatacaa ataagaggca ctatagtttg tttgctgact taaactgata
     1261 atcgaatttg tctgacagct gaacaaagaa gtcaagatct gataactgac tgattcgttg
     1321 cagtatcttc caaatagacg ataatagcag taagccggat caattccttc aaaattcaac
     1381 tttaaaaaag gtttttgctt atcaatatgc agttctgtta gattgagacg ctcaaagtct
     1441 tgttctaatt ctttgatgta tagtaaaaaa tttgattcag acatatggaa atgatctgct
     1501 aaatattgtg tagtaataaa gaaacgatgt tcagatagga aaagaaaaat atctaatttt
     1561 gtattgcttt ttttcttcaa gagaaacgtt ttaatcgctt cttgagtttg catgaaagag
     1621 gctccttttt acttaaattg ttaaaacttg aaaatattac tgtttttttc ataaatttag
     1681 acaaaaaaac agtaaacata taggtagaat ctctactatc ttatttcttg catacaaaaa
     1741 aatcaaggag tgagagagtt atgagatatt caaccatctt aatatcaaca tttgcagcct
     1801 taagcttatc gcttactata aatcagacag tccacacaga ggagatagaa acagccaaat
     1861 ggacagaaac caagtgggcc aacgtcaatc gaattacctt tcaggatgaa ttttcatcct
     1921 tcaattcagg agtcgcaaaa ttaagaaaag gacaaacagc gaccatcaaa gcaaaaattg
     1981 actattcagg agacttagca cctatactac aatcagctgt tacatttgag aatgttgatc
     2041 ccgctttgtc gattggctat gacgagaaca ctttgactat ccaacacaag caagcgatat
     2101 ttaccttcac cgttacatta aatcaggact tgttaaaacc agcgcttttt actgtcaagg
     2161 tatcagatgg actaccgaac gatcatcatc atttaacgcc gtatagtcag cggcagacaa
     2221 ttgagcaaga ttcagctatc gactcaggag gagatcttgt tgaagaacca acagataaac
     2281 cagaaaatga aaataagcca gaagtaccgc ctacagaaaa tccagacgga gaacagaaac
     2341 cggaaataga acctggagaa gaacccgata cagaaactca accagagcca gacaatgaat
     2401 caaaacctga aataacccct ggagaaaaac cagatgtaga cccagaagaa aaaccggatg
     2461 tgactccaga accagatacg gattctggaa accaaacagt accggaaaca aatccagaca
     2521 cagataatga aactgaaaat ccagaaaaac cagaggtagc cccagaagaa aaaccagatg
     2581 taactccaga accagatacg gattctggaa accaaacagt accggaaaca aatccagaca
     2641 cagataatga aactgaaaat ccagaaaaac tagaggtaga tccagaagaa aaaccagatg
     2701 tgactccaga accagatacg gacgcaagag accaaggaat accagaaaaa ataaacaaaa
     2761 aaacaattca agaggatgga aaaaaagaga gtaaaaaatc aaatctagca attctaaaaa
     2821 taaatgaaga gcagctgaat aaaaaatcac gaatatttga tagcgcccaa tcagctgaaa
     2881 ccttaaaaag tagcaaggat acaacctttg ctagtcctga aacgaaaaat aaacagctac
     2941 caaaatccgg agagtcacaa aacaaagtta tactgtggag cggaatcatt ctattaagta
     3001 tagcaacaat gctttctgca aaaagattta aacaaaacag atctctctaa catttgaata
     3061 atgtctgtga acgcattttt caaataaaaa gaaatatcca gaaaacgacc ccaaaatacc
     3121 agattgaaat ctgatatttg gggtcgttca tactttatct ttcttcatat ttattttaag
     3181 ggatatctgt ttcttttgga agatggttcg ggatcttttt cactttcaat acatctaaaa
     3241 agaaggtaaa gatcggaatg ccgacaatca agccccaaac gccaaagaac cgttcgctaa
     3301 caagtaagac cacaaatgta taaaaaatcg gcagttctgt tttgctggac atcaacttcg
     3361 gattcagcac ataagactca attagatgga caatcaaaat cgtaatcagg atataaacaa
     3421 catctcggat gcctccttgg gaataagcta tgaaagatag aggaatacaa gaaatgataa
     3481 cacctgctac tgggatcaga cttaaaatga aaatcatgat cgctaaactc agcagctgat
     3541 gaaagccaaa tacagccaag gcgattgtag tgagcaacgt gtttaaaaga gcgataacaa
     3601 attgagcttc taataccaaa ccaaatgtat tgacaaactt atcggcaaaa tagtaaatat
     3661 cttgaaagaa ccaagaaaat tcacttttta aaaacaatct tgagaataca attgtttttt
     3721 tcttttcaat cataaaaaag aaacttaaga tgaatgacat agcaaacgcc actgccattt
     3781 ttcctatatc ctgtaaatag ccaagcgcaa tcgaagcgcc attttgaagc tgttcaaaaa
     3841 aatcgtttcg ctcaatataa gtatggatat attgtaaaac aggatctgca tcttttggct
     3901 gatgctcgta aaaatcaata acggactgga tcatatcaaa tgtttgatga ataagcatcg
     3961 ggatatactt tgtgaatgcc agatagataa ggtaaacgat cagtgtataa atcatgatag
     4021 ctaaaacacc tgtagggatt cggacaaatc gctgaatgat ttgaacaaga tgaatcatca
     4081 aataagtaaa gataaatgtg agcaaaatgg ttgtaatcat acttctaact aagaaaagaa
     4141 caaaaacgac aaataataaa acagtgagac ggcgtatttt ttcattcgcc aaaaaacgct
     4201 gataaacggt caaatcgaca acctccaaat aacaaaaaat aaacacgtta ttcattatat
     4261 gatggaatat gaaaataaga aagagaaaga gcaaaaagaa aaaccgctaa atgacgttat
     4321 cttatgagtt ggttttcctc ataaaatcgt tcatctagca gtttcagccc tttttctggt
     4381 cttgatgaaa attatctagc atttttcggg tcagatgttg cagtgtatcc aattcttcct
     4441 gttcaagtgg aagataagac ttgatctttt gtggaatacc ttctgcttgt ttttgcaacg
     4501 cagcaccttg aggagtcagc gtaacattta cgattctttc atcacccgtt tcacgctgac
     4561 gattaatata atttttttct gctaactttt ttagtaaggg agtcagcgta ccagaatcca
     4621 gacacaaatc atttcctagc tctttcactg aagtcttttt cttttcccat aaaactaaca
     4681 tcacaagata ctgggtatag gtaagattca gcggcttgag gagggaagtg tagtgtctaa
     4741 tgatttcctt agaggcggca tataaaggaa aacatacttg attaactaaa tatagatctt
     4801 ccatttttcc acctccgctg ttttactata gtgtatcata gcggatttac acaaaaaagt
     4861 ctattcacta actgctttca gagtaacttc tatatttcca gctgtagctt ttgaatacgg
     4921 acacacttta tgcgctgcct ctaataattc ttgcgtttct tccagagaaa gaccttcgat
     4981 agatccttca atctctacac ctaagacaaa gctcgtttca ctttctgaat aaagggaaac
     5041 ttgtgcactg acagtagaag ccccagagat atttttttgc tgtttgatca attctaatgc
     5101 actgttaaaa catgcactga aaccagctgc aaacaattgt tcagggttgg ttgcattttc
     5161 gacgcgttta ccaggagctg caatattcaa ttcgaatgta cgatcgggat tatgaacttc
     5221 tccagagcgt ccgcctgtgt tgatcatttt cgtagaatac atttttttca taaaattacc
     5281 acctttaatt atattttata caattgaatt ttacacaata taattgtgga aagcaaagaa
     5341 atggattggc ataagataaa taagagaaag cacatgaaac agacgcgctt tctcgaatag
     5401 caaacatata caaaaaaata tcagagacaa aaactaatct catcataaac attacatata
     5461 tttctcaaaa agttgttttc tttcttcaaa acttacttca cgatggacct gatgaagcat
     5521 ccataaataa ccaaaaggat ctctgaacat tgagttagtc acaccaaagt ccatcatttc
     5581 tgtcatttct tgaatctcta cacagccatt tcgtaatgct ttattatgtg tgtcctcgat
     5641 atcagagacg atgatattga accagatcgt atttggatgt tcagcagtag gagcagtcaa
     5701 accaagagac gtgttttcat ccagcatatg gaatctcgtg ccatacaagg taaaaatgac
     5761 ttcattattg cctctagggt aatctgttgc ctcaatcagt tgtatttcat caaagattgt
     5821 ttgatacagt tctagtgctt tcaaactatc atttaataca aaatctattt ccgttccttt
     5881 atgcataaag atctcctctc cttttcagtc gaacagttac tagattcttt tattatacca
     5941 gttaaagaaa acgcattcaa aaaaatagcg gatttactta ccaactcatt cgattggatg
     6001 ataagtaaat ccgcgtccca ttacttctgc tacgctgctg acaatgacaa aggcacttgg
     6061 atcgatttct tctatcaatg gtttcattcg ggaaaattca tgatcagtca caacgatcaa
     6121 taaaacctct tttgactttc gattataccc gccttttgcc tctagcaggg taaggccacg
     6181 tccaatctca gcacttaagc gaaggcggat gtcttccaaa taatgttcac tcatgaccat
     6241 aacagatttc tttcgattga tacctgtttc gatataagtc atgacaattg aagtgattgc
     6301 aatagataaa atagcataaa gaaactcttc tattccaaaa acaaacagat taagagaaac
     6361 aacgaatgcg tctgtaaaaa ataagccaat cgaagtattc aagtggaaat attttttaaa
     6421 aatgagggga gggatcgtcg taccgccgct agaagagttg tttttatata aaatcgcaac
     6481 tcctaaagca aaaatcgcac ttccaaaaat gacagacaac aaccgatctg aagtaatcat
     6541 tgtttctgga actattgcaa tgattaaagg aaaaaacaag cttccgaaaa gtactttaaa
     6601 aaagggtttt ttacctaaaa atagaagagc tagtaccaac ataacgatat tcaacactaa
     6661 aataactata gctcggtcaa atcctaaaac agcttccagt aatattccta gaccgctgac
     6721 acctccagca gcaatatgat gaggccctaa aaacatattg atagcgactc ctaatatgaa
     6781 gagggcaaaa ataatcttaa tgtatgtcca tataaattgt ctcgtttctt tcatttatcc
     6841 acttccttaa ttcattaata atactcttat cttattataa cttacttttc accttaagtt
     6901 aactttaatt aataaaaaaa ttaggctagt ctaaattatt atgtttcatt cttctagaat
     6961 atacttctac gttaaaaact gttaaaaaac ttttacttta gaaaattgga gaaattgatc
     7021 gcttaagata aattcaggac actaaatagt acaggaagta gattaaaact tttaaaagtt
     7081 ttaagtctat ctatttggca agtttaaaaa ataaaaattc ggtatcaaaa aactgttacc
     7141 gataacattt ttgaaagcgt tgtcttttgt ttctctatca cttatagtga tgacgtcata
     7201 ttaaaacaca aggaggaaat caatggatac agctgcaatt tatcatcgac cggaaagtga
     7261 atatgcattt ctatatacga atacaagatt tcgtattcgg cttcgtacta ggaaaaatga
     7321 tatcaaaaaa gtatatgtgc tttgtggaga tccatatacc ataacaactg aaaaatggta
     7381 tcaaaaacaa cgaccaatga aaaaatgtct aagtaccaat gttcatgatt attgggaaat
     7441 tgaagtgacg agcgaaacaa ggcgcttaca gtatgcgttc catgttgttg gggaagataa
     7501 cacggactgt ttttacggtg atcaaggaat ttttccttat cgagaaaatg tgattactga
     7561 accaaatttt tattttcgaa taccttattt tcatcaaatc gatcgattca ctattccaga
     7621 atgggtaaaa gaaacagtat ggtatcaaat ttttcccgaa agatttgcaa acggggacaa
     7681 agcaaatgac cccgaacaca ctttaccttg gggaagtaaa gatccagacc gagaagactt
     7741 cttcggggga gatttgcaag gtgtgaggga tcatttggat tacttgacgg accttggcgt
     7801 caatggcatc tatttttgtc ccatatttaa agccacatcc aatcataaat acgatacgat
     7861 tgattattat gaggtggatc ccgcttttgg cgataaaaaa cttttaaaaa acttgattga
     7921 tgaagcacat aaaagaggga tacgtatcat gttcgatgct gtattcaatc atatgggtgt
     7981 ccattcacca cagtggcaag acgttctcaa aaacggagaa aaatcgatct ataaagactg
     8041 gttccacatc cgttttttcc cagtagattc ttatcagatg actgacttac cagaaactgc
     8101 tgaaaatatc ccatatgata cttttgcttt tactccattc atgccgaaac taaatacagc
     8161 aaatccagaa gtgcaaaaat atttgctgga tatcgcaact tattggataa aagaattcga
     8221 tattgatgga tggcgtcttg atgttgctaa tgaagtcgat catcattttt ggaaaaaatt
     8281 cagagaagca gttacagaaa tcaaaccaga catctatatc cttggagaga tttggcattc
     8341 ctctcaagct tggctgcaag gggatgaatt ccatgcagtg atgaattatg cattcacaga
     8401 ttcgattaaa gattattttg caaaaaagaa aatcacagct tcacaaatgg tcagtggaat
     8461 gaatcatcag caaatgcttt acagagatca ggtgaacgaa ggaacattca acttattaga
     8521 ttctcatgat actgccagga tcttgaccct ttgccaaggt aacaaagaat tgatgaagtc
     8581 tgtgatggcc tttatgtttc ttcaaaaagg gtctccttgt atctattacg ggacagaaat
     8641 agggatgact ggtgaagatg acccggattg ccgcaaatgt atgatatggg agaaggagga
     8701 acaagatcta gagctattcg gttttataaa agaacttgtt tctctaagga aacagttgtc
     8761 taagattatt tctgaaggtt ctactcagtg gctaatagta tatgatcgtg aagataagct
     8821 ctatttcaca cgggaactag agggacagat catctatgtt tactttaatc agtcaaaaga
     8881 accttgggta gtagaacagg aaaatgaggt gattcttagt caaaattgtc agttgttaga
     8941 agacgggaaa gcagagatac gacaatacgg atttttgatc atgtgttgaa aactgttacc
     9001 ggtaacaaca agaaagcgtt tgcaaatgaa gatttgtgcc cattataata agggtgtaac
     9061 agcacgttga atacacagga ggaaatgaag atgaaaaaaa gaagtgtgaa acagttgggt
     9121 ttagggttaa tctctttagg aatcttaggc ggattagcgg cttgtggcaa tggtaactct
     9181 tcagcagaag gggaagccga tgaaggaaaa acgttaacag tttccgttga ttctggatat
     9241 aaagattata taaacgaaat aaaaaacact ttcgaaaaag aaaacgatgt gaaaatcaag
     9301 ctagtagaaa aggacatgtt cgatcagttg gaatcattag cgttagatgg gcctgctgga
     9361 aagggacctg acgttatgat ggcagcatat gaccggatcg gtgcgttagg acagcaagga
     9421 catctggcgg aagtaaaact gggaaatgaa gcagcttacg atgaaacaga caaagcccaa
     9481 gtgacttatg atggaaaaat ctacggagaa cctgcagtaa tcgagaccct tgttttgtac
     9541 tataacaaag atttagtcga tacagcacca tcaacgttta aagatttgga gaatctatcc
     9601 aaagacagtc gttttgcttt tgagtcagaa gcaggaaaaa atacaggatt tttagctaaa
     9661 tggactgact tttattattc ctatggttta attgcaggtt acggtggcta tgtatttggt
     9721 gatgatggca caaatccttc agatatcggt ttgaataatg caggtgctgt agaaggaatc
     9781 tcttatgcaa cagattggtt caaaaatgtt tggccaaagg gaatgcaaga cataaaaagt
     9841 gcaggagact tcgccagcca gcaattcatg tccaataaaa ctgcagcaat cattgacggt
     9901 ccatggcaag cgcaaacata caaagaaaac aatatcaatt atggtgtagc caaaattcct
     9961 actctaaata atggacagcc ttatcaaccg tttggcggag gaaaaggatg ggtagtcagc
    10021 aattatgcta aaaacaaaga cctctctcaa aaatggcttg attatgtaac gaatcaggaa
    10081 aatcaagaaa aattctttga aatggtaaat gaaatccctg caaaccaaca agctagggaa
    10141 acagcaaagg ctaaaaacga tgaattaaca acagctgtga ttgaacaata tgaaacagct
    10201 caagcgatgc caaacatccc agaaatgggc gaagtttgga caggtgcaga aaacttgatg
    10261 ttcgatgcag catcaggttc aaaaacacca aaagaatccg cagatgaagc agtaaaaaca
    10321 atcagtgaag ccatagaaca aaaatactga ttaaaatgat aaccgtccat ttttataaaa
    10381 aatggaacag gtgcttcaga taaaagtggc aagagcgaga tggaaaatta tcttgctctt
    10441 gttgccatta tcttaaaagc agtttgcggt ttagcaagtt tagagggggc attcagatgc
    10501 agcaagataa aacaagcaat atcaacgaaa aaaaaatcac gctttgttca cttattccag
    10561 ggatggggca gtttgtaaat ggccaagctt ttaaaggtat cgtttttttc gccatattcg
    10621 tcctattcat tggtcagatg cttctgggcg gatttcatgc attggtagga ttggttactt
    10681 tgggaagtat accaatggaa gatcattcat tatttatttt gattgaaggc actttgcaat
    10741 tcatcattac aatcattttc ttgatttttt acggtttgaa tcttttagac gcttatcgag
    10801 tagcgaagat gcgtcaagag ggcaaaaaaa tcaatcggac gatgaaggaa gtcatacata
    10861 atataggtga tgaaggtttt ccttatctat tgacacttcc cgcttatctt ctcatgattt
    10921 ttacgatcat tttcccagtc ctagttacat tgttcactgc atttactaat tatgacttca
    10981 atcatattcc accagccagt ttaattgatt gggtaggggc taaaaacttt tttagtatct
    11041 tctttttaag ctcatatcgt aatacttttt ttgcagtctt ttcgtggacc gtgatttgga
    11101 ctttatgtgc aacaactttg caaatcaccc ttggtattct cacagcggtt gttgctcacc
    11161 agaaatttat taaattcaaa cgtattttcg gtatcatttt cttattacca tgggcggtcc
    11221 cagcttttat tactatcatg agtttttcga atatattcaa cgatagcgta ggtgccatca
    11281 atactcaagt gattcctttc ataaaccagc ttccttttgt agatatcagt gcaatctctt
    11341 ggaaaacgga cccgaactgg acgaaagtag caattatctt agtgcagggc tggttaggat
    11401 ttccctatat ctatgtgatg gttacaggaa tcttacaatc gatttcagaa gacttatatg
    11461 aagcagcaaa aatcgacgga gcaaatgcat ggcagcgctt ttcaaacatc acgcttcctg
    11521 ctgtcttcct agtggcagcg ccaacattta ttacacagta tacggggaat ttcaataatt
    11581 tctccatgat ctatctgttt aacaatggtg gtcccggaag cgtaggcgga ggagctggtt
    11641 ctactgatat tcttatttcc tggatctata aacttacgac tggaacttct ccgcagtatt
    11701 ctatggcttc agcaatcacg ttgattatct ccgtcatcgt tatctgtgtg tcattgctgg
    11761 tatttaaaaa gacaaatgcg ttcaatatgg gggattaaca atgaaaaaat ttcattcgag
    11821 tgctcgattc caaaaacgac tttctcactt ttttacttac ttttttcttt taatactgtc
    11881 agtcattatc atctatccgc ttttgatcac agcaagtact gccttcaagt caggaaatat
    11941 tgcagctttt agtttagatc tttcaagtga ctggacttta ggaaacttta ctcggctatt
    12001 cagtgaaaca ctttacggga cttggtataa aaatacattg atcatttctg tcctaacaat
    12061 gatcgtacaa gtgactgtag taactttggc gggctatact tatagtcgct atcgttttat
    12121 cggccgcaaa tcaagtttga tgttcttttt agtgattcag atggtaccga ctatggcagc
    12181 attgactgcc ttttatgtca tggctttctt attagaagcg ctcgataagt actggttctt
    12241 gacaatgatc tatataggcg gtggaattcc aatgaatact tggctgatga aaggatactt
    12301 tgacactgta ccaatagatt tagatgaatc tgctaaactt gatggggcag ggcatttcag
    12361 gatttttttc cagattgtat taccgcttgt caaaccgatg ctcgccgttc aagcattatg
    12421 ggcttttatg ggaccttttg gggatttcat gttagctaag ttcctgcttc gaacacctga
    12481 aaatcagact gttgctgtcg gcttacaaac atttatttct gatgtgacaa accaaagagt
    12541 ctctcttttt gctgctgggg caattttgat tgcactaccg atttgtctat tattcttctt
    12601 tttacaaaag aactttgtta ccggcctgac atctggcgga acaaaaggat aggagcagag
    12661 tatcatgcaa acatttccgt taaactattt ttccgcatta cgtacgccaa ctcaagtgtt
    12721 tgcgggacgc aaactattat catggcctaa atttttcttg atatttgtat ttttagtttc
    12781 cttgatggtc atgcctgtga ctctttttta tgccaatcag atccaagcga ttccattaga
    12841 acaatttcta tccgttcatt cgctgatcga tgaacaagga acccaaaaat tttctgaact
    12901 tgaattatct gaaactgggt tacaagcatc gcaacaaacg atagctgtga cccctgaaat
    12961 tttggtaggt gtgtctttat ctgagaaaca acaatccgat catggaactt ttattgattt
    13021 tgagaaggaa caatgggtga tccaacaaaa ggataaatct ggtatacgcc gctatacgat
    13081 gaattatagc ccatctttcc aaccagattc tgtacgtacg cccgaagatt tccaacgatt
    13141 tttagaaaga gaattttatg ccagtaatcg tccaacaatc attttatctt atagtttaag
    13201 tcttggtctt gtcctatttg tcatgacgag tctcatttta ttcggggctt cctttttctt
    13261 gtggatgaca agaaaaagcc aactttcatc cattcataca ttcaaagaga gtgcaaattt
    13321 gatgctgaat gttatgggaa taggttccat ggcagcagca gttgtagggt ttatccactt
    13381 tgactttatc ttgatgctaa gtgtccaaac aacgataact gtcttgctgc ttttatgggt
    13441 ttttgtcaaa acaagattca aagataagcg tgtcgaatga caagtttaag cgatttatgc
    13501 gacaatgaat gtgaaaaaaa tgaaaaataa agtagttttt gaaaaatttc tgaaaaaatt
    13561 aaacttctta gttgattctt ttctttttta gtattaacgt aatagggtag tttttttaag
    13621 gaggaaaatc atgttagaga aaactttata caatcaatta ttttcacgtt ctttctcgct
    13681 ccctgtcgaa gtaaattatt gggacggtac aacgaaacaa tacggagata cggacactcc
    13741 tccccaaatc aaaatcaata tccatgaaga aatcccaatg aaagagatta caagtaacgc
    13801 ttctttggca ctaggagaag cctatatgga tcatcgaatc gagatcgagg gaagtatcca
    13861 agcattgatc aacgatgctt atcagcaagc aaacagcttt ttacgaggaa aagattatct
    13921 aaaatggctg ccaaagaaag aaaaacatac gaaacaaaaa aacaaagaag atatccatgc
    13981 gcattatgac ttaggtaacg acttttataa actttggcta gatccaactt tgacttattc
    14041 ttgtgcttat ttcaatacac ctgaagatac gttggaacaa gcacaaatca ataaagtcca
    14101 tcatatctta gacaaactct ttatcaaaga aggcgaaacg ttgcttgata tcggttgtgg
    14161 ctggggaaca ttgatgttca ctgctaccaa agagtataat gtcaaggcaa ctgggatcac
    14221 actaagtgaa gaacaatacg atttgattac caaaagaata aaagaagaac atttagaaga
    14281 taaatgccgt gtattattaa tggattaccg cgaactaaaa ggcgaaacgt ttgatcatat
    14341 cacaagtgta ggtatgttcg aacatgtagg ttctgaaaat cttgaaggtt atttcaaagt
    14401 ggtaaaagat ttattgaaac caaaaggaac agctttgatc catggaatca gccgacaaca
    14461 aggcggtgcg acaaatgctt ggatcaataa atatattttc cctggcggtt atgtccctgg
    14521 tgttactgaa ttagttgata atattacaaa aaacgatttg caactgattg atttggaaag
    14581 cttacgtcgt gactaccaat tgacattaga acattggaca aagaattttc atcaagtcca
    14641 agatcaagtc acgaaagaaa tgggtgattc cttctatcga atgtgggatc tatatttaca
    14701 agcttgtgca gcttcatttg aatcaagtaa tatcgatgtg attcaatatt tgcttgttca
    14761 acctggaaac aatgacatcc caatgcatcg tgcataattg aggcaaaagt actgtttaaa
    14821 gactatttaa aaagaagcta agttttatga tgctccagaa gtgaactttt ttgtctaact
    14881 tctaggattg tctctaaagc ttagtttctt tttctttata ttttcataat aaaagtttgg
    14941 ttctttaatt tttaaacatg acagaaaatt ttttcttcgt tatacttgta atagaatact
    15001 attttataac aaaggggatc gaatcaatga aaaaaactgt tatttatact agtttatttg
    15061 cagctttgtt tttagctgct tgtcaatcaa ataccaatca aggcacatct gggaatacgt
    15121 cttccagtag cgaacagcgc tcttcacagg tatcggactc ctcaacaaaa gcaagcacat
    15181 cttcgtctag ccagacaaaa agttctagtg aagcaagtac tcagtcagat atcaaagtgt
    15241 ctgcagctcg tgcgatcgaa ttgttccaag ataaataccc agatactgca attactagtt
    15301 tggaattaga tagtgattgg ggatcttact tctacaagat agaaggtgtc gatgatcaaa
    15361 aagaatacga agcaagaatt gatgctcaaa atgaaaaaat ggagacagag aatccagaaa
    15421 ctctagatcg agatgaacaa aatggtcaaa agaaaaaaga agatggtctg gatgttgata
    15481 aattgatcac gattgaggaa gcagcaaaaa tcgccgtcga caaagtagga agcggtacgg
    15541 caacagattg ggatttggat aaagatttag gtactactta ttgggaagtc aaagtaaaag
    15601 acggcaatca aagtacatca gtcaagatca atagccaaac aggcgaagta ctgtcaactg
    15661 aacaagatga ttaagaattt cttcggaaaa caagagttga tttttctttt agtcatgata
    15721 cactagacaa aataacttgt ttgaaggagc gatttacttg agtttagaaa cgacctttgc
    15781 caatcatatc tttgccaatc ctttgatgaa tgcatctggt gtccactgca tgactaccca
    15841 ggaattagat gaactggctc attcagaagc aggagcattt atcactaaga gctgtacgat
    15901 caatgaacga aaaggaaatc ccgaaccacg ctattttgat gttcctttag ggagtatcaa
    15961 ttctatggga cttccaaact taggtttttc ttattatcta gagtatgctc ttgcgtatga
    16021 aaaagtgcag gaaaaccaaa atcaaccgtt atttttttcc attgccggga tgagtgtcca
    16081 ggaaaacttg gaaatgcttg agaaaataga aaaaagtggg tttaatggga tcactgaatt
    16141 aaatttatct tgtcccaatg tgcctggaaa accacaacta gcttacgatt ttgaggccac
    16201 ttatgaaaca ctgaaagaag tattcagcat cttttctaag ccgctaggaa tcaaattgcc
    16261 tccttatttt gattttgctc attttgatca gatggctgat atcttgaatc agtttccatt
    16321 gacctatgtc aatgctatca acagtgtggg caatggtttg tatatcgata cagaacaaga
    16381 agcagtagtc atcaaaccaa aagaagggtt cggcggcatt ggcggagagt atatcaagcc
    16441 gactgctttg gcgaatgttc gcgcttttta tacacgtttg aaaccagaaa tccaaatcat
    16501 tggtacaggt gggattcgga caggacaaga tgcatttgaa catctgctat gtggcgcaag
    16561 catgttacag attggtacag agcttcataa agaagggccg gaaatttttt ctagaatcat
    16621 aaaagaatta acgcagatta tgtcagaaaa aggatatacg tcaattgacg aatttaaagg
    16681 caaattacgc accatttcat agcaaagaga cgaaggtcat gattgatctt cgtctttttt
    16741 tataaaaaac actcgtctgt tcattcctgt gcaagcgtac tcattgtatg ttagacgaac
    16801 ttgtgggaaa ataacagagg caaaaaggag gataatatga atgatgcaac agaattagca
    16861 aaagagctta aagaaaaaga atttagtttt caagaactag ttacggatat acagaaaaaa
    16921 ataaagaagc aaaatcatga attgaatgcg tttgtcgcgc ttgaaccatt cgagagtaat
    16981 tcccacgagc tattgattcc ccagtcagaa aaagggccat tggctggtat cccatttcct
    17041 ttaaaaatgc tcggtcaaga aaaaaaggga tggctagcta cttcaggatc tcgtttattt
    17101 gaaacacacc gagcttctca tacatctaat tatgtgcggc aagcagaagc gataggtcta
    17161 gttccttttg gacaaaccaa tgcgccagag tttggtttca aaaatattac agacccagtc
    17221 atctatggcc cagcaagaaa cccttggaac cttgaatgta caccgggcgg atcaagtgga
    17281 ggagctgctg ctgcagtttc atcaggaatc gttcctttag ctggtgctag tgatggcggt
    17341 ggttctatta gaatacccgc ttcgttttgc ggattgattg ggctgaaacc ttcgcgaggg
    17401 acgatgccag ttggtccata tgcttggaga ggatggcaag gagctgctat tgatttcggc
    17461 ttgacagttt ctatgagaga cacggaggct ttattttatg ggatgagaag tatccattcc
    17521 ggtgcgccat atcaagtatc gccagttgag tggcaaacac atccaagaaa aaaacggttg
    17581 aagatagctt tttgtgttga ttcaccgatc cactcacaga ttagtgaaga ggcagtactt
    17641 gctgtaaaaa aagctgtaga tttccttgga aaagaagggc atgatttgac agagattcct
    17701 tacccactag atggtcgtaa actgatcacg tcttattatc agatgaatgg cgcagaaaca
    17761 gcagcaatga tccgctcgat tgaaacaggc atccagcgag ctgtcagaaa agaagaactt
    17821 gaacccattt cttggacttt gttccaatat ggtcagaagc tctctgccgc tacttacatc
    17881 gattctctgc atgtatggga tgaagcagca attgtcatgg aaaacctaca tcaagaatac
    17941 gatctattcc tttcaccaac gactgcattt accgccccta aaatcagcga agatttgcaa
    18001 agtgatgcga taagagcaca gatggaacac atcagtgatt gttctgaagt agaaggttta
    18061 gacgttgttt cttccatgtt tgaggagagc ttgaagatca caccttatac acagttggct
    18121 aatctgactg gacaaccagc aatcagcttg cctactcatt tgacaaaaga aaacatgcct
    18181 ctaggaatcc aatttatggc tgccagagga agagaagatt tgctatttca aatcggctat
    18241 ctatttgaag caaatcatca gttccattta ccaaatccat ggaaatagca gaaacaagga
    18301 gaagaagaat gaagaaaaaa agattgtttg ctctaataac tagtgccttt tttattttaa
    18361 gcgcttgcgg tacagctgcc gctaatcagg aagataacag ctggagtaat gtagaaaaaa
    18421 agaaagaatt agtagtagcg acttctggca cactgtttcc cgcatcttat tataatgatc
    18481 aaaatgaatt agttggttat gatgtagatt tggcaaaaga ggtggctaaa cggttaaatg
    18541 tcaaaatctc ctttaaagaa tacaacgtgg atggacaaat cacttctgtt tcaaaaagag
    18601 aatcagattt tgctgcgaac gattttggta tcacaaaaga aagagaaaaa aaattctccc
    18661 tttcagagac tttcaaatat tcatttgaca gtatgatcgt acgaaaaaaa gatgattcag
    18721 gaatccactc acttgaagat cttaaaggga aaaaagcagc tggcgaaccc aatactagct
    18781 atatgcgttt agcggaaaaa cacggagcta aattagtcac atatgacaat gccacgaatg
    18841 atcagtattt aagcgatgta gcaaatggtc gaacagatgt tattctaaat gattattatc
    18901 tgcagaaaat ggccgtatct gctttaccag atatccctgt aaaaatactg gagaacgttt
    18961 atttcaatga aaacgaaagt ggttttttat tgaaagaagg aaatgatgct ctgaaaaaga
    19021 aaatcgatgg cgtattaaaa gagatgaaag aagatgggac gacaaagaaa atatctgaaa
    19081 aatattttca aactgatgtt tcagtcaaac cgaaagaaac gatggctgag tcggtgagtg
    19141 agtgatgtac tttcctctaa ttgatttttc cctcatgtgg acttcacttc ctttcgtact
    19201 gcaaggcttg gtatacacat tagggattgg cttcgtgtcg tttcttttag gaaatttggt
    19261 agggttgctt ttgacagttt taggtctttt ggattggctg cctctgaatg tatttattcg
    19321 tttttattta tcgttcttta gaggcattcc cgcactagtc ctgctgtttc tgttatattt
    19381 cgggttacct tatcaattaa gtgccttaac ggcttcagtc atctgcttta cgattaccag
    19441 cagtgcattt attggtgaaa tctatcgagg atcactagca ggcgtttctt caggtcagtg
    19501 ggacgctggt ttagcttctg gtttttcttt ctttggggta ttgaaatata tcgttttgcc
    19561 gcaagctttt cgaatctcag taccggcact cagtaacgta gctatggatc tagtgaaagg
    19621 tacttcgtta gcagcaacaa tcacagtgcc agaaatattt caaaaagcaa agatcatagg
    19681 cggtcggaca ttcgattatt tttctctcta tattttagtt gcactgattt attgggtcat
    19741 ttgtatcggg atcgaaaaag tgcaacagta tttagaaaaa cgttctatcc atcagtcaat
    19801 ctgaaaaata gaaatggtgc tagcgtggct ggcaccattt ctattttttg tttcttgtat
    19861 attctgccta gtattttaaa accatttcat gtaaaatgta aatcgaaaat atgttcggag
    19921 gtagaaaaca tgaagacccc gctaaccatc gaaatagaat cctcgttata ccaatattgc
    19981 atcgagcaag gcggcttggt tgtagaagaa gtcacgatgc ctgatgacca aggaattgta
    20041 gatacgctta gctgcttgac aaaatttgat ggaagccgag aatggcgatg ctatgagctg
    20101 aaagtgacaa aagcagattt tcgctctaca gccaaactgt catttgttgg acattataat
    20161 tattttgttt taccaagtaa actatatgaa gaagtaaaaa ctgaaatccc tacaggaata
    20221 ggtgttttag tgtatcgtcc gtacacggtt gaagaggaga tgcctgcctc tggtacattt
    20281 ctgattgcga aaaaagcagc aaagaaagag cttgctgtac cggaagaagc tttgacaaac
    20341 cgcttcatgg cttctttatt cagggaagta agaaaagcaa agcaaatgga gcgaggcgta
    20401 aaatattttc caaaagatca attgtacaaa gaattgaaaa gacgttcaga aaatcaagat
    20461 ccattttcta acgaacgata ttatgaacgg tttttagagg aaatagctag tcaggcaatc
    20521 aatgagttgc aagaagaagt tatcgcgctt cagcatgatt atgaatattt gaggcaacaa
    20581 cagcagatcc gtcggttgcc tacagagcca ttggagtgaa aaatatgtac tatccttatt
    20641 taagaggaaa acaatttgac ctattagcat taaaagaagc actgtcgcga ggattgctct
    20701 ccaataaaat ccaaccagtg atcgaaccag tacgtgattc cgctacgctt aaaaatgtga
    20761 tcgaattatt tcaaaaaaag caccatccaa tcgctgtgat ccaaaatccc caagtaggac
    20821 aattcaaatt attcgatcag catgtgcaca gttggacagt caaagaaaat agctctgtcg
    20881 tccctgcaca gatcttaacg ccagaaaatc tcagtgaagt actggattca cctccagcgt
    20941 ttcttgtttt cgatggacag cactacccaa aagatacaga ggtgtggaaa cagttggcag
    21001 gagttgattc gaaatttttg ataccagata ctagtcgctt tcgcatctgg ctgcccgaaa
    21061 acaaaattgt gatccgtgac tcttttcaaa cgagaaagca tgttgaaagt tatgcagata
    21121 aaacagatga cttttttagt gatgactatc tttttttcca cgcagacgga tatattggat
    21181 tttctgattt cacgatcgaa ggtagccgtt atttcgataa agggttccct agccgagcgc
    21241 ttgctatcca tctaacgtat attgatgctt acggcaatat acgcgtgaaa cattttgtct
    21301 ctgacagtaa cgactctgct aaagaccaag cattgaagtt tcttgaagca ggagataaaa
    21361 tgaaaaaatg gatcatgcgt caccatcatc aactcttgat tacttcagga atgattgaat
    21421 tattggctct ttaccagcaa caaaaattcc ctggactggg agtgttgaaa aagtggtcac
    21481 ttatgcatca tttggaactt attagtcacc tgctagatca tccaaaagat tggcttaaat
    21541 attattcaaa agttcaggaa ctatatgaag tgatccaatg attagataat gtaaatgaaa
    21601 aaggaataga aaagaggaaa ctggatgtat attcggcaaa caaggaaaga agaagtagaa
    21661 gaagtggtag aaatcattaa tgccgcagcg gatttcattg cttcgcaagg ctctcctcaa
    21721 tggcaaaacg ggcagaaacc aacaaaagaa acgattttga acgatattga aagaaaagaa
    21781 agctatgtat taatagtgga agatcaaatt gctggaacag ctgcattagt ctcaggcgtg
    21841 gatcccgttt acacaaaaat agatggtagt tggaaagaat caactggtcc ttatttatcg
    21901 attcatcgtg tcgctttagc agaaagtact cgaggaaaaa aactagcaaa accgttctta
    21961 gaacatttgt tgacgattgc agccagcaaa aatatccaag atatccgtat cgatacttat
    22021 ccagctaatg aaccgatgga aaagaccatc tattctgctg gattcactta tcaagggatg
    22081 attgaatttc cttttgaaca cggcgaaaga aaagcatatc aaataatcat caattgacta
    22141 taaaatcatc tgagcaaaga taaagacatt aacactactg aaaaaaacaa tcatatgata
    22201 gccaagaggt tgtaacagaa gtggccagct tcaaaaaaca agaaagaatt tccgaaaatg
    22261 cttctcaaat ttttgtggaa ttttagcgta ttttacgaaa tagctgcttt ctgaaactcc
    22321 cttcatcgag aggtcgtgac atagcttttg tcacgatctc tcggcttatc ctacgagtat
    22381 tattcgatac atttatatca ataatccttt ttttatttta tctgcagctt cttggaacgc
    22441 tccatcgttt gacacgacta aaagtgaggg gatagctttc aaacgtttca actgtgctaa
    22501 atcttctaca taaaccgcca gtctggctga aatctgttca gatgaatctc cacgtttttt
    22561 caggcgcgat tgcaatgttt ctttagagat cgtaataaag ataggacgga ctaccgtccc
    22621 gaaatactca tataaatgcc aaaaaccatt tgctgtcaaa acggcgtaac aatttcctac
    22681 tgtcagtttc tttttaattt ctgctttact ggaaccatat ttatgttgag catattggtc
    22741 ccactctgca aactcatttc ccttgatcat ctgattgaat gtattgtcag aaacaaaata
    22801 ataatcctct tgatcttttt ccccaggtct tggtgatcga ttcgtgtaag taatgatctt
    22861 ttgttccggc tgaaaaatag cttctgcgag tgaagttttt ccagaaccag aaggaccgat
    22921 aaatacatag caataattca ttgtcatttc tcctttgatg attgaacaag tgaaaaagct
    22981 ttggaaaata tttccaaagc ttttaaaagt aactttgctt ttttgtattt tataccagca
    23041 agccagtcac aatagcactt aaaaagctga ctaaagtcgc tgttagcaaa attttcaatc
    23101 cgtgttttgc gacaagattt cctttttctt catttaatcc cttcatcgca ccagaaatga
    23161 tcccgataga agagaagttg gcaaatgaaa cgaggaagac agatataatt gctgttgtac
    23221 gctcagtaaa atggaaatta ccatttgcta attctgtcat agcaacaaat tcatttgtaa
    23281 ccagtttagt cgccatgata ctaccggcat ccactgcttc tttccatggg attccgctga
    23341 tgaaggcaag aggggcaaag atgtaaccta ggatctcttg gaaagtgatg ccgaatatcc
    23401 cgtggaagat agcattgatc atggcaatca aagcaacaaa accgataagc atagcagcaa
    23461 ccgtgatcgc cacatggaaa ccatcaagaa tgtattctcc caacatttgg aaaaatgtct
    23521 gttctttgtt ttcttcaatg atcagctcat cttctttttc ttctaataca tagggattta
    23581 caattgaagc cagaatataa ccgccaaata agttcaaaac aagggcagtg atcacatatt
    23641 tagaatcgat cagtgccata taagatccga cgatcgacat agaaactgta gacatagccg
    23701 atacactcat ggtgaacaaa cgtttctcag ataggaaggg taattccttt tttatggaaa
    23761 taaaaacttc cgattgtcct aaaatagcag aagctactcc attataagat tccaatttgc
    23821 ccatcccgtt gattttactt aatcctagac caacagcttt cataaataat ggaagaatct
    23881 tgatatagcg tagaataccg ataatagcag aaataaatac aattggcatc aatacggaaa
    23941 gaaagaaagg tgcacttcct ttatttgcta caccggcaaa aacaaagtca acaccttgcc
    24001 cagcaaaagc aagaagatga tcaaacattt ttgccaatac agaaacaacc gctgtaccaa
    24061 aagttgtacg taataatacg aaaccaagaa caagctgtaa aacgaacatc acaattagtg
    24121 gtttcaattt gattgctttt ttgttactgc tgatcaaaaa agcaagccct aatgtgacaa
    24181 ataaaccaat aatacctaat aaataactca aataatcact cctattccaa attccgtttt
    24241 attttacctg ttttgcaaat aaaatactaa tctttagtga aattttcatt acttttttag
    24301 agtgaaacgc attcattttc cattagaaaa taaagcgaac aaaataaaag gtttaaaaag
    24361 tgtaacgtct tagtaaagtc tataaaaaaa cgaaactatc gattaagcta atagtttcgt
    24421 tttcaacatt tataagtaaa ctttttctat tggtaatata gattttcgga agggtagaca
    24481 ggtgcgcagg taatatcgat tcctagtttt ttcaatgttt gttcatcatt tttattgacc
    24541 atcacagtag agtgggcttg tgctccctca agttcagcta gtttatcata agcaacttga
    24601 gcgattggat tcgttactgc actgattgat aaagcgatca agacttcatt gatgcttagt
    24661 gcatccaaag aggaatgaag tgtctttgat ttcaatcctt gtattgtttc aagaactaat
    24721 ggtgacaata aaggaatgtc atctgcgata tgggctaaat gttttactgc atttaagata
    24781 actgccgctg acgcatccat caatgaactt gtacgcccgg taatgatgac ttcatctggt
    24841 aattcgattg caatcacagc agaaggatct tttgtaggac tttgcgcttg aatcttatct
    24901 gcatagtcat gggcagggac taccacgttt cggtcttcag gacgtaaacc gacttcttcc
    24961 ataatcagtt tgattcgatt aactgcttct tcgtcgatca atcctttttt gaagtcgcat
    25021 tctgtttgga aataacgacg gatgatttct tgtttagagg cttcttggac aacggtatca
    25081 tccacgatcc caaatcctac acgattcaca cccatgtcag taggagattg ataaacagat
    25141 tctttaccag taattttttc aataatacgt ttgattacag gaaatgtctc aacatcccga
    25201 ttatagttca cagctacttt attgtaggca tcaaagtgga aggaatcgat catattgaca
    25261 tcttttagat cgactgtggc tgcttcataa gcaatgttca gcggatgttt caacggaaca
    25321 ttccatactg ggaaagtttc gaacttggag taaccagctg catgtccttt ttggctttca
    25381 tgatacagtt ggttcaagca agtagcgagc tttccacttc ctgggccagg agctgtcact
    25441 acaacgattg gtttagttgt ttcaatatac tcattttttc caaaaccatc ttctgagacg
    25501 attttttcta cgttgactgg atagtcttcg atttctgagt gtttatagac cttgatgttt
    25561 cgtctttcta gtttattgat aaagactttc gtggcaggct gtccactata gcgagtgata
    25621 acgacactgt tgattaataa gccataacca cgtaattcat cgattaaccg caagatatcc
    25681 atatcataag taatcccata atcaccacgg atcttattac gttcaatatc tccagcatag
    25741 acgcaaatca gtatttcagc ttgatctttc aatttttgca gcaatttgat tttcgcatct
    25801 tcttcaaatc ctggaagtac acgtttcgca tgcttgtcgt caactaactt cccaccaaat
    25861 tctaaatata atttgtcata gtggttcact cgttccaaaa tatacgctga ctgctcttca
    25921 atatattttt ctgaatcaaa accaattttt ttcactaggt tccctcctta agtactaaag
    25981 cattttttca tttttttgag gattcgtcaa ctggaagagc gaaattcctc aaaaaaacaa
    26041 agaaaatggt ttaaaccaac ttgtctagat agttattcat tggtatgata gtttttgata
    26101 aggaaggtgc tacatgaaaa aaagacagaa aaagaaaaac gcatataaac actatatccg
    26161 ttcgattttt accggttatg aaagaatgct tgaagatccc gaattggaac aattgacgtt
    26221 tacttatcta aacgaagaaa cgcagctaac tcgtgatgag catcagcgca ttcatttcac
    26281 aacaagagat ctgcctagta aataaaaaat aagataaagg tcatcggatt cgattctgtc
    26341 ctatcagatg gaaagactag ttgatcgaaa aaaaggctgt accaaatttt ggtgcagcct
    26401 gttttatgga gcattgcccg ctctttttta taacaatttt ttacagaaaa tggtactatt
    26461 gaagtattaa taagtgaaaa acagatgagt aagaggaggc aagtagtatg aaagagccag
    26521 atacaaatgc aaattatgag ccagacgaac tagaggagac gaacgcggat caggatacag
    26581 gacaagaatc gtcttctttt tacgatatca aagaaaaagc aagcatgaat ctttcccaat
    26641 tattagaaga cttacaggct tttgaaaaag ctgtccgcga agaagatatc cctgagatct
    26701 accgtttata caatggccga ttgaatgaag aattaaaaag aagctcaaat gaaaatcacg
    26761 agatcgatca attgctgatg cgtaagatcc atgatcgttt tttacaggaa tttcctttta
    26821 tggaacaagt agaaaacatc tcgccaacga tgagctatta caaaatcggc acttattacc
    26881 atgatcggcc cacggtcggt attgatgcaa gtctgccaga aatttttgtt ttgcctaaga
    26941 tcgatgaaga gtgggagaaa tattcccaac cggagtcaac ggactatgac aaaaaaatca
    27001 atgagctaga cgcaaaggtg atcactgctc agacagaaat tgaacgttta gatgaacaaa
    27061 taaaagaaat caatcgacaa atgactgatt tgaacgacaa taaaggattc ttgaatcgta
    27121 aaaaaatcga ggaagaaatt caagaattag agaagaagaa gcaagtacta tctaatgaaa
    27181 aattaggctg gcttccttat attgagacgc ctgaaacaat ccagcagcaa aaagaagcat
    27241 tgaagcaaga agcaagagca gaccagcttc gtgcagccat cgtagaaaaa gaacaaaggc
    27301 aaatcagacg ctatttcggt agcaaagagg gattcggtca agcaatccat gaattcttga
    27361 tgaattatct tggcaatgag aatcctaata atcaatctaa tgaaggaggt tccgagtatg
    27421 aatgaacacg atgaagcaga atggacaaaa aatgaagaac aaacagaaga tcatgaagaa
    27481 acgaacactt cattggaaga acaaacaagt aatcctctgg atgacacaga agaaatccct
    27541 atgctagagg aaacaaaaat acatgaaaaa gaaaaagtaa ctccgacgaa tacgaatact
    27601 gcagaaaaca cccatgctta cgaaataact gaaaatcccg ggtatttaga aggaaaagag
    27661 caagatcatc aagatatcgt cagtttgatt gaaacagcgg aagcagaatt agcggattta
    27721 cgtatgagaa aagatttgat cgaatcagat tttccacaat tattagaatc atatgatcgt
    27781 tttatattga atgaagaacc aatctccacg atcggaaaga caagcctgat cgaatacttc
    27841 acgtatgaat tactgaaacc gttgaatgat attggtctgg aacggtcaaa ttcagcttat
    27901 gacacatgga aaacaagaca tttttcgatc aattatacgt tgaatggaca aaacgaatta
    27961 gtcttttcct ttgtattacc gaccatcgat caacgatacc aagtggaatc gatgagtctc
    28021 ctaaacgtat caccagagac aatggaaatc aatgtccaag atgaccgggt gctttctttg
    28081 atccgacact ggtcagtgga tcgagtattc tctgcagggc agatcacgat attcaatcac
    28141 aaattgaatc aattattagc ccatgcaaga acacttggtt ttaccgttaa tcagacatta
    28201 ctagacaata cgaagccact tcgtttgaat cttcagagcg aatttgaatt gacgaatgaa
    28261 gtattggatg atatttttat cgtggcaatg aaaaatccat cctacgatat ggaaaagatc
    28321 aacgaaacta cttatcaagt acgattagat aaaggacagt ctttaacgat aacaacaaac
    28381 gaaaaagatc aaacagtctt gtcgatctca tctggagact acccacgatc tgtcattgat
    28441 ttctttatca attacgaatt cttggtccca ttaatggtga gaaagtcctg attggataag
    28501 ttggattacc agatgtcatt cagataattc tgttccaaag gacttgcggc agttatccag
    28561 aataattgtc acaagtcttt tctgtatgta ctaaatggac gtgaataact tgctgatgaa
    28621 ggagggattt cattaggaat gtccacaaat aaaatagcac agcttagctt attgtctgct
    28681 gcttgtgtag caggtaggat cgcttttcaa tttattccga atttccagcc aatgactgct
    28741 atttttttat ttatagtact ttacttaagc ttaaaagatg cgttaattgt catgagtctt
    28801 tctattgcga tcagcagttt ttattttggt gttggaccat gggtcatcgg ccaatggatc
    28861 agctatactg ttgttctgag tttgttttca atcgtctgct tgagaaaaac agtgcaaagg
    28921 aatctatggt taaagggagt ctgttttttt ctggcgggca tggtttacgg aataggtatg
    28981 accgtttttg atacgctgtt atatcgtttg cctcaacctt ggatctatta ccttcaaggg
    29041 gtgtcgtttg atttgatgca cagtataggc aatgttgtgt tctttcttgt ttttctgcca
    29101 gtcgtcaaac gtttttacaa tcattcagga ggaaaaaatg aaaaaaataa tttatagttt
    29161 gcttgcaatg agtgtcagta tactcatttt gacaagttgc agtacaacct atacacaatc
    29221 ggcttccaac caaaaggagg aagtaaaaac atcgcaaaaa gcaacaatca cgttacaaga
    29281 aaatggtcaa aacttttcgg aaaaagaagt ggtcttcaaa aaaggcgatg atttactgag
    29341 tattttgaaa cgaaattttg aagtcaaaga agataacggc ttcatcactt cgcttgaagg
    29401 gcactcacag gatgagaaaa atcaactcta ttggatgttt actgtggacg ggaaaagtgc
    29461 tactactggt gccaaagaga tcaaattgaa tgatggacaa tcggtcattt tcaatttgtc
    29521 taaactataa gtttcataaa aaactgttaa agggcgaata ttgccataat tcagtgagtt
    29581 cagttgatga aagaaggaaa ataacatgga aaattttaaa aaaagcggaa tgttttccgt
    29641 aattgctgct ctaggggcta atattctagt tgctatcagc aaatttgtcg gctatgcaat
    29701 cagtggcagt gccgccatgc taaacgaaag catccacagt atcgttgatt gcagcaatca
    29761 gattttgctg ttattcggtg ataaacaagc caataaagga cagagcgagt tgcatcaatt
    29821 tggtgaagga cgagcaaaat actttttcag tacaatcgtc gcaatgatgc ttttcttcgg
    29881 cggtggggca cttggggtga tggaagcttt tgaaaagttg acgcatccat cccatgaagt
    29941 gggtaatccg atcattgtta tagcaatact gttatttggt ttggtaatcg aaggaagttc
    30001 gttacgcgtg gcaatgaaag aaatcaaaga attgaatact gaaaaacttt ccacgatgcg
    30061 ctttttgcgc gaaagtcgac acagtgaaat actgattatt tttacggaag acttgtgtgc
    30121 tgtaatcggt ttggtcttgg ctttagcagg aacaatattg acttatgcaa ccgggattgc
    30181 tgcatttgat gcgatcagcg gattgctgat cggtttcttg ctgatgggag ccgccatttt
    30241 cctagcaaaa gaattttata gtctgatcat cggtgaaagc gtgacagcaa gcgatttatc
    30301 aaaaatcaag ttagcttttg aacgtcctga gatcagtcgg ctgatcgata taaaaacagt
    30361 tcatttaagt ccaacggaga ttttagttgc agcaaaagca gatatcgttg gtaacaaaga
    30421 gaatgaagct tactcggtca tcaatgatat tgaaaaaaat atgcgtcagt ctcttcctga
    30481 caagaagatg tatatataca ttgaaacaga taaatatgac ccaaattatt ctcgtaaata
    30541 aaacgtttat tcatgaattg aagcaaaaat gagaaaaata taatcttgtt tttaaataaa
    30601 acggctacaa tttagcgaat ttatgttaca atgagtccgc tgtttatttg ttgtaattaa
    30661 aggagatatt ttaatgaaca aaaagaaaag tgcgccatgg cttcaagctt tgcatgcagt
    30721 gatgccactt tgtataagct atataccagt aggattagct tgcggagtat tgttgcaaaa
    30781 agttggattt gatcctctct tatcaggact gttatcgatt ctggtctttt ccggtggcgc
    30841 gcagttttta gttgcatcta tgcttacgac gcaagcatca tttgcaacga cattattgat
    30901 ggttttcttt ttagaattac gctatacatt attaggagca agtcttgccg gttttatgaa
    30961 aaaagaaaag cggacgtttt tggctgtctt ttctcaatca ctgaatgatg aaaactatgc
    31021 ggtgaactac ttaaagtttt caactgaccc ttcctggaat aaaagaaagg ctttatatgt
    31081 caattggttc tcaatgactg catgggccgg tagcaatatg atcggtaatt ttttcggctc
    31141 ggtgattcga gtagatgctg accttgtcca ttttgctttg acggccatgt tcattttcat
    31201 gtttatcatg cagatgaaaa gcgcactact gatctttaca ggtttattct caggcgtatt
    31261 aggggtcgta ttcatggtat tattccaaaa tactttcgga ttgattgcag caacagtcat
    31321 tgcttcattt gccggattta tgctggagaa ggcattcaaa aaagaaaaag ctaagaaact
    31381 aagagaccgc ggtaaagatg tcaatgagcc gctcttcaac ttcccggaac aggaggccaa
    31441 tcaccatgac taaactatat ttgctacttt tagttgcttg tctgttcatc gtggcatata
    31501 tcccgcgctt gttcccgatg ctttatttta ctcatcgaaa agtgccatcc tggttcagtg
    31561 actggatgaa atatgtaccg gtggcattat ttgcggcgtt agcttttaaa gatgttttca
    31621 ttactcatga acatctggat attgcttgga atatcaaaat agctgcaatg attctagtag
    31681 caggcgtggc ttacaaaaca cgttcgatgg cgttgtcagt tttgacagga cttgcgtctg
    31741 tctttttgct gtctatgctt taaactgttt tattttatta aaaacagaga ttgcgacata
    31801 agttgttcaa actgatctat ccgaactgca tttgcaacag tcaattctgg atgcaagttt
    31861 attcgtaggg ataaaaaaga ttagtgttgg cttatgatgc aagctctttt ttattttagg
    31921 aattagagag ggatttgtcc ttctatgatt ttttgctata atagggaaga tgtttatttt
    31981 atgaaagaat agttgaggga atttaaatga ataaaaaatt gatgcaagga acattttggc
    32041 taacctttgc taatcttcta tgtaaagttt taggggtagt ctatttgatt ccctggctaa
    32101 gtatgatggg gaacaatcaa gatggtatgc ttgctacgac attgtataat gttggctatc
    32161 ttccttatgg attgttcctg atgcttggta cagtcggatt tccaaatgcg attgcaaaaa
    32221 aagtagctgt agccacaaaa gaaggagata acgctgcttg tcggctgatt tttagaagta
    32281 cgatcaatat catgtttgtc atcggtatcg cctctgctgc actgatgtat ttatttgctc
    32341 ctttactagc cggaatcagt ccgattgcta acgttaataa tgggatacta gctatcagaa
    32401 gtttatgccc atctttgatt gctatcccaa ttcttagtgc aatgagagga tatttccaag
    32461 gaaaaaatga tctgcggcct tatggaactt ctttgattat cgaacaggct gtgcgagtga
    32521 tcgttatctt ggctggtact tattacttgc gcgtattgac tgacggaacc atattagaag
    32581 ctgtattgat cagtacagtc gcttctttct tcggtgggtt agctgcgatt atccatatgt
    32641 atatcgtcgg acgcagaaaa gacttcttcg aacttaaaga ttttttgatt tccagccgtt
    32701 atttcgaaag agaaaaccga tctgcctctg tctctatcat tcgggaaaca ctaccgttta
    32761 tttttgtcgg ctcagtcatt actatcgttc aaatgatcga ccaagtaacg atgaaaccac
    32821 tgcttcactt tttccgtcca gagatcgcag atcagcaact ggaattctta ttcagccgtg
    32881 cttctgtcaa tccaaataaa ttgacattga tcctgatctc catggtagga acagtagcta
    32941 taagcagctt gccaatatta agcacgatga agaaaaaaga tcggatacaa atcgaaaaaa
    33001 cagtaggaga tagtttttcg attgcgttat tgattcttct tccttcattg actggaatgt
    33061 ctttattagc tggaccacta tacacattgt tttttggcta tgatcctgaa agtgtcggat
    33121 atttccaaat ggctttgcta gcttctttgt ttttctcttt attcacgatc ctatctacga
    33181 tgcttcaatc tttgaatcac catcgttttg cgatccgatt aactgtagaa gcaattatcc
    33241 tgaaagtcat cttccaagta atcggattag gattagttgg cggatacggg atgagcttat
    33301 caaatggctt agcattcggt attgtctttg ttcgcggcta tcactttatg tgcaaagaat
    33361 accgaatagc acctttagca aagatcagca attttttctt aaaaactttc cgctccaccc
    33421 tgattatgct tgcagtatgt tttgccgttt tctttttgct gaatcagcga ttgtcaatgg
    33481 aatcaaaaag ctatgcaatg atttattgtg tggctgtagg aagtattggc ggcttagtat
    33541 ttttattttc tcaattcgga aaaaatgggt ttcgaatgtt gaaaaatgtt aaacatcata
    33601 gcagaagcaa agaataggtt aactaatcgt tttttgctgt cacttgaaaa acggcaactc
    33661 gtatgattac gcttgtcgtt tttctatttt ccaattttag tttcatatct aatcttactt
    33721 atgatatagt tataaggtct ggaaaaattc tttgaaacga ggaaattaaa cacatgaaac
    33781 ttgcagtagt tacagatagt tcggcatatc tgccggaacg tatcaagaac catcccgact
    33841 tattcgttat tccaatccct ttgattatgg atgggaaaat ttataacgaa ggaatcgata
    33901 tcgaagcgga tgaatattat ggacttttaa aaaacagtaa agattttcct actacttcac
    33961 aacctgtcgt aggggaagtt ttgggtttat atgaggaatt gaaagagaaa gggtatgaca
    34021 cgattttaag tatccatctt tcttcaggga tttctggctt tgtcaacaca ttatttgcga
    34081 tgaaagatga catcagcgga gtaacggtca ttccttatga ctctaagatc actagtatgc
    34141 cgatgggaca catggtagaa gctgccttag acttaaatga tgaaggtcag tcccttgatg
    34201 aaatacttgc acatatcgat cgaatccgag ataataccta tgcttatctg attgtagatg
    34261 atttgaacaa tttagtacga ggaggacgtt tgacaaatgg tgcagcgctg attggcagct
    34321 tattaaaaat caaaccgatc ctgacatttt ctgaagggaa aattgtttta ttcgaaaaaa
    34381 tccgttcaag taaaaaagca tttgctcgag ctgaagaaat tattggtaga agaaataacg
    34441 aaatacaacc gccagtcaaa ctttacgtga tacatgcaaa taatttagaa gtagcgattg
    34501 cggagaaaga gaaattgcag aaaaaatatc caaatgcaga aatcgaaatt ggtcatttcg
    34561 gaccagtcat tggtacacat ttaggtgaaa aagccatcgg cattgccatt tcagcgcaat
    34621 aattcctttt attcaaaaaa cataccaaaa at
//
LOCUS       DACCVZ010000024        33957 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.024, whole genome shotgun sequence.
ACCESSION   DACCVZ010000024 DACCVZ010000000
VERSION     DACCVZ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33957
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.024"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(29..1261)
                     /locus_tag="IVW63_001159"
     CDS             complement(29..1261)
                     /locus_tag="IVW63_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAP7859446.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1516..2085
                     /locus_tag="IVW63_001160"
     CDS             1516..2085
                     /locus_tag="IVW63_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7859447.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2263..2703)
                     /locus_tag="IVW63_001161"
     CDS             complement(2263..2703)
                     /locus_tag="IVW63_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAP7859448.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2861..3625
                     /gene="map"
                     /locus_tag="IVW63_001162"
     CDS             2861..3625
                     /gene="map"
                     /locus_tag="IVW63_001162"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAP7859449.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3657..4580
                     /locus_tag="IVW63_001163"
     CDS             3657..4580
                     /locus_tag="IVW63_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAP7859450.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4805..5044)
                     /locus_tag="IVW63_001164"
     CDS             complement(4805..5044)
                     /locus_tag="IVW63_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7859451.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5049..5468)
                     /locus_tag="IVW63_001165"
     CDS             complement(5049..5468)
                     /locus_tag="IVW63_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP7859452.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5695..6933)
                     /locus_tag="IVW63_001166"
     CDS             complement(5695..6933)
                     /locus_tag="IVW63_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004081244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7859453.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7040..7675)
                     /locus_tag="IVW63_001167"
     CDS             complement(7040..7675)
                     /locus_tag="IVW63_001167"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7859454.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(7789..7881)
                     /locus_tag="IVW63_001168"
                     /pseudo
     CDS             complement(7789..7881)
                     /locus_tag="IVW63_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(8017..8652)
                     /locus_tag="IVW63_001169"
     CDS             complement(8017..8652)
                     /locus_tag="IVW63_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7859455.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9164..10306
                     /locus_tag="IVW63_001170"
     CDS             9164..10306
                     /locus_tag="IVW63_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP7859456.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10299..10505
                     /locus_tag="IVW63_001171"
     CDS             10299..10505
                     /locus_tag="IVW63_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAP7859457.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10584..11777
                     /locus_tag="IVW63_001172"
     CDS             10584..11777
                     /locus_tag="IVW63_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP7859458.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(11784..11942)
                     /locus_tag="IVW63_001173"
                     /pseudo
     CDS             complement(11784..11942)
                     /locus_tag="IVW63_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788611.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-binding domain-containing protein"
     gene            11982..13121
                     /locus_tag="IVW63_001174"
     CDS             11982..13121
                     /locus_tag="IVW63_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HAP7859459.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13114..13914
                     /locus_tag="IVW63_001175"
     CDS             13114..13914
                     /locus_tag="IVW63_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP7859460.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13914..14741
                     /locus_tag="IVW63_001176"
     CDS             13914..14741
                     /locus_tag="IVW63_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP7859461.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14719..15453
                     /locus_tag="IVW63_001177"
     CDS             14719..15453
                     /locus_tag="IVW63_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP7859462.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            15553..16419
                     /gene="rfbA"
                     /locus_tag="IVW63_001178"
     CDS             15553..16419
                     /gene="rfbA"
                     /locus_tag="IVW63_001178"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAP7859463.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16433..17005
                     /gene="rfbC"
                     /locus_tag="IVW63_001179"
     CDS             16433..17005
                     /gene="rfbC"
                     /locus_tag="IVW63_001179"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAP7859464.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17027..18055
                     /gene="rfbB"
                     /locus_tag="IVW63_001180"
     CDS             17027..18055
                     /gene="rfbB"
                     /locus_tag="IVW63_001180"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAP7859465.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18153..19004
                     /gene="rfbD"
                     /locus_tag="IVW63_001181"
     CDS             18153..19004
                     /gene="rfbD"
                     /locus_tag="IVW63_001181"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HAP7859466.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19038..21071
                     /locus_tag="IVW63_001182"
     CDS             19038..21071
                     /locus_tag="IVW63_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859467.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21115..22395
                     /locus_tag="IVW63_001183"
     CDS             21115..22395
                     /locus_tag="IVW63_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HAP7859468.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22605..23411
                     /locus_tag="IVW63_001184"
     CDS             22605..23411
                     /locus_tag="IVW63_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7859469.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23423..24643
                     /locus_tag="IVW63_001185"
     CDS             23423..24643
                     /locus_tag="IVW63_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7859470.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24633..26219
                     /locus_tag="IVW63_001186"
     CDS             24633..26219
                     /locus_tag="IVW63_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7859471.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26258..28396
                     /locus_tag="IVW63_001187"
     CDS             26258..28396
                     /locus_tag="IVW63_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP7859472.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVCPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28764..29747)
                     /locus_tag="IVW63_001188"
     CDS             complement(28764..29747)
                     /locus_tag="IVW63_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HAP7859473.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            30125..31516
                     /locus_tag="IVW63_001189"
     CDS             30125..31516
                     /locus_tag="IVW63_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAP7859474.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            31532..32572
                     /locus_tag="IVW63_001190"
     CDS             31532..32572
                     /locus_tag="IVW63_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP7859475.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            32591..33676
                     /locus_tag="IVW63_001191"
     CDS             32591..33676
                     /locus_tag="IVW63_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAP7859476.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            33709..>33957
                     /locus_tag="IVW63_001192"
     CDS             33709..>33957
                     /locus_tag="IVW63_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAP7859477.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQ"
BASE COUNT        11002 a         5822 c         6695 g        10438 t
ORIGIN      
        1 tattttttgc atgtgtgcga aagtatactc aagcccaatc gccatttcgg aaaatcggta
       61 ctgtagagcc atcttcacgg attccgtcga tatccatctt gtcagatcct accatgaaat
      121 ctacgtgggt ttgacttcta ttcaatccag cttctgctaa ttcttcatcg gacatttctg
      181 taccgccttt cacactgaag gcataagcag aacctagtgc taagtgattc gatgcgtttt
      241 catcaaataa tgtattgaaa aagatgatgc cagattgaga aataggtgaa gggtcaggta
      301 caagtgcgac ttctcctaaa cgacgcgcac cttcatctgt atcaagcagt tttgctaaga
      361 catcttctcc ttgttcggca gaaaaatcaa caacttttcc atctttaaaa gtaaatttca
      421 tacccgagat gatggtgcca gcataactca gtggctttgt acttgaaatg taaccatcta
      481 ctcgatgact gtcaggtgct gtgaacactt cttccgtcgg catatttgcc atgaattttt
      541 ctccacgagc attatagctt ccagcgcctt cccaaagatg gtttttaggc aatccgataa
      601 tgatatctgt accgggagca gtatagtgaa gggcagaaaa ttgttctcga ttcaattctt
      661 ctgctttttt tgctaatttt tcatcatgct tcttccatgc taagacaggg tcttcttcat
      721 agacacgagt cgttttgaaa atctgatccc ataatgcctc aacttgtttt tcttctggca
      781 gttctgggaa gacttttgct gcccattgtt taccagccgc agccacgaca gtccaactga
      841 ctttatttgc ttgagttgcc ttgcgtaaat tcattagtgc tttgccattc gctgattgat
      901 aagacgctac tcgatggcta tctacaccag caaatgcatc gggatcggca gaaacaacgc
      961 tgatcctgct tgctcctttt tcaagccatt catccgcttg atcgatttta gattgtggta
     1021 cattctcaat acgatccgtt gcagcatgta aaagaaattc tctttggatc tggtcgtcag
     1081 tccattgaac gataacctca gcggctccta gtttataagc ttcttgtgtg atcaatcgag
     1141 caaggggtgc ctgttccacg ctgatctgta aaacaactgt gtgtcctttt tctgtggcta
     1201 cgccagtttc tgcaattaag cgtgcatatt tttttagaag ttcattaaaa tcagataaca
     1261 taataaaaat tcctcctcac cattttttct ggtaactatt agcatgatac catttaatta
     1321 tgattcaaac aatgaggctt taaataaaaa aaggaggtta tttttttaag gttaagtttc
     1381 atgatatatg ttactacttg ctatttcagc ttgtgaagaa aatcaaaaac taattttgca
     1441 tatcaaaaaa aacatgttac aatgaaatta atcaatggtg gaagcgttat aaaaaaatta
     1501 aggagattaa aaaatatggc aagaaaaaag acgattacta gagaacagat tttggcagct
     1561 gcttatgaag tagctgccac cgatggattt acacgattta ctgcgagaaa catcgcgaac
     1621 aaaatgaatt gttccacgca accgatttat cttgagttta aaaatatgga tgacttgaga
     1681 caagctcttt ttgagcagat ctatgatcat ttacaatatg aagtgttcac tgttgagcat
     1741 acagggaata cgattatcga tcttgctttt aattatatcc attttgcaag aagagagaag
     1801 aagttgtatc gttcactgta cttagaagaa tatggtggag gaaaagagat gcagaatttc
     1861 tcttatactt actttgtgaa tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa
     1921 gagcagatcg aatctttgta taatgggaca tggatcatag ctactgggat cgcagctttg
     1981 atgtcttcaa gcatcatcca tccaactgat gaacagattg aaaagatgat ccaagacagt
     2041 atagatgcta tcttgaaatt caaagaacca atcgaaatcg attgaatata ctcaaaagtt
     2101 ccacaaatca gtaggtaaca agagatgtgt caaaataagg aaaagttcgt ttttcttaca
     2161 gcgtatgcat ttttaactcc cgaagaactc ttccatgaat gcaatgaata aaagagccat
     2221 acagattgaa taaatctgga tggctctttt attgcaagta tattaaattt ttgcgactag
     2281 ttctttagcg aaagcttcta aattttcgat atcttcttct tcagcattca gatccacttt
     2341 aacattttcg gctccttttg atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac
     2401 cgatttgcag aattcatcgt aaaaagtatc accagatccg cagacaccgt aaatttttcc
     2461 caatagatcc aattcttgca agtcttcata aaagtctacg atctcatcag gcagatcgcc
     2521 atcatcgtat gtataagtag ctactacgca aatatctgcc tcctcgaatt catctgcatc
     2581 tacttgggta cattcgttga tttcgacttc gatatccaga ttttcaaatg cttctgcaac
     2641 aatatcggcg atttcttcag tgtttcctgt catgctagca tatacgattt ttgctaaagc
     2701 catgatgtgc ctcctcgttt ataattattt aacaattatg aattatacca aaacatcatt
     2761 gaaaagaaaa taaaacctag agacacctgg ggaatgtcat ttggctaaat gtatgccgct
     2821 atgttaaaat gagagggatt tgtaaaaagg agacgaaaat atgattactt taaaatcagc
     2881 acgtgaaatt gaaatgatgg cagaatctgg agctttatta gcagatgtac ataaaaatct
     2941 gcgtgatttt ataaaaccag gaatcacaag ttgggatatt gaggtatttg tcagaaacta
     3001 tatcgagagt catggcggaa ttgctgcgca aattggcttt gaagggtatg aatatgcgac
     3061 ttgtatcagt ataaatgatg aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa
     3121 cggtgatttg gtaaaagtcg atatgtgtat cgatttgaaa ggcggcattt ctgattcttg
     3181 ttgggcctat gtagttggag aatctacacc tgagatcgac cgattgatgg aagtaacgaa
     3241 gaaagctttg tacatcggta ttgagcaagc acaagtaggg aatcggattg gtgacatcgg
     3301 tcatgctatc caaacttatg tagaaggcga aaatctagcg atcgttcgtg attttattgg
     3361 tcatggcgtt ggtcctacga ttcatgaaga accagcagtt cctcattacg gagaagctgg
     3421 aaaagggttg cggttgaaag aaggcatggt tatcacgatc gaacctatgg ttaataccgg
     3481 aacttggaaa atgaaaatgg atcctaacgg ctggactgcg tatacaagag acggcggact
     3541 ttcttgccaa tatgaacata cattggctat tactaaagat ggtccaagaa ttttgacatc
     3601 acaaggagaa gaaggcactt attgatctat ccagtcaata ggtacgggag aggtacatga
     3661 aagtttggaa caaaataaaa caaaatgaaa atctgatgcg ctttattgag acgactcaaa
     3721 agcgcatcac tgattcagaa atgagtacga cctctgtcgt cgttgcttat tatttactct
     3781 tgtctttatt tccattgatt attgcttttg gtaatatttt accgtttctc cacatcgatc
     3841 aagagactgt actgacctat ttacgagaag tgattcctga gaccgtttac cagtttatcg
     3901 gtcctgcaat caaagacctt ttgacacaaa gttcaggagg cttgttatcc gtttctgcat
     3961 tagcggcttt atggtctgca agtcaaagta tcaatgcttt gcaaattgcg atgaataaag
     4021 cgtatggcgt agaaaataga aaaaattttt tgatcgtccg tttcttctca ctaattgtca
     4081 ttgtcttgtt catgattgct attagtgggg taactatcgt tcttgggttg ggacagctga
     4141 ttttggatgc tattcagcca atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa
     4201 ctttgaagtg gccaatcaca ttggtagctt tatttgtcat catgttcttg atttatttaa
     4261 ttgtccctaa tgctcagttg aagttgaaga cgatcattcc gggcacgatc ttcgctactg
     4321 tcggctggat gctgttatca caagtgttta gtatctatgc taggtatttt gcaacgagga
     4381 tcagcggtta tcagatcata ggaagtttta ttgtactcat gctttggctt aattttgctg
     4441 ctacgatcat cattttgggc ggaatcatca atgcagttgt tcaagaatac gtgacgggtc
     4501 atcaaatcaa aaaacgtcga gatccaagcc gaaaatggtt caataaattg aaaactaaat
     4561 tttctcataa aaaaaagtag aaacaagagt tcttattgta aatttatatc agtaatttat
     4621 ttgaaatttt atatctaatt ttcaattatc cgcataaaca ctatacattc aagcattttg
     4681 aagtatagaa aaacactcat cttaccacga atttaccacg attgaatgag ccttgatatg
     4741 accgtaaaac tactaaggga gatagcacga aactgtgtat ctcccgattt ttttatacag
     4801 ttgattactt cactccgatt tcaaatttca atattgcttt catcatgtct gtatgaattt
     4861 ctccttttag ttcttcatca acctgcataa tgattttacc actttcagag tggtaaaaag
     4921 gacgcaagca taatttagaa atataaccgt cataaaactt caaaatctct ttaactgcca
     4981 tttcatctcc gcttgacgct ttgcaaatca attcaaaaga gggatagcca taatctttac
     5041 tcatttcttt acttcctttc gctcaaaagc atttttaact tccttagtcc tctagttctt
     5101 ctactgcaaa tagcagaacg tgatacatgg tacagttctg aaatttctct gtcgttcatt
     5161 ccttgaaaat aacgtaataa aatcgcacta cgctgttttt ctgacagtct atgtaaaact
     5221 gtaccaagtg tttcatcaga tacataaatt gtaaagtgca agactttaaa tgatacacaa
     5281 tcataaaaac aggtatcaat cgttccacgt tcaacttgtt tcgtttcggc tatttcacaa
     5341 aacaatactt cacgtttaga atgtcttgca agctgtctgt ttcgactttt cactttgttc
     5401 ttaatgacaa tcagcattaa agaattgaac tgtaatctga cgatatgctc gaaagaagat
     5461 gtcctcataa tctcaccccc tttctgctaa tgctgaaata tataaacgga ataccgttta
     5521 taccctttag aaatacagaa aaatggtaag aaaaaagccc acacaaaaca tatatttgtg
     5581 cgagccttaa atactgcaat attactcttt cttttataac actatccttt tagcagattt
     5641 caaattttct tttatatatt gtttttagcc taacatacta tttaacccct tgtattatat
     5701 ctctaacttt tgaaaaattc tttttgaata tattgaaatc atgattgaag caatagaagc
     5761 tacaaacata acaacccatg tttcttgtat aaatacatcg aataaaatac cgtaaaccat
     5821 ttgtccaata ggttgaccgc acatagcaac tgctaccagc gtagccatta tctttcctac
     5881 taattgcggt ggtgtttgtg tctgaacaag agtgtaaatt tgaacaacaa acatagtaga
     5941 tacacccata gccacaaagc acatcactgt aactacccag taggaaacta ttgcaggcaa
     6001 ttctaaaaat agcgaaattc ccataagtaa aacagaaaca gaacaaataa gtaacaaggt
     6061 ataaaggttt tttagtttta actttgaagc aacaagagct gttaaaatac caccacataa
     6121 accacctaat gataatgctg attgtgaaaa accatatagt gtatctggca tttttaaaac
     6181 ttcagaaatt aagataggca gaccaacaat taaaacagca cttaaaacca aattgaaaat
     6241 gcaaaccaaa aagattacgg atataaaaat gggtttctcc tttttcaaaa aggtataact
     6301 atcttttaaa tcgtttttag caactgcaat tacacctact tcacgaggtc ttttttggtg
     6361 tggaatatgg ataaaaattt ccataatggc tgaaaaagta aaacatataa tactaacaat
     6421 taaaatggga ttgataccat aaaattgaaa aactactccg cttatagctg gtccgataaa
     6481 gtttgctaaa gtatttactt gatttattat agcattaccg acggtaagtt tatctgatga
     6541 taccaataga ggaatacttg cttgtaccgc tggttgatat gcaccagaaa taccataaag
     6601 taacatcaaa gcaacaataa acaaaggtat gataggaatt tttcccaatg acaaataaaa
     6661 tactaaaatt atgattgctg ttacaaaatc tagtatgacc ataatgtttc ttttatttgt
     6721 cctgtcagca ataataccac ctaccagcga caaaataacc ataggtaaaa aagagcaggc
     6781 tgtagcaata ccaaacaaag ctgatgaacc agtttctttt aacaaatagt acggtaatgc
     6841 aaatcgtagg atagcgtttc caaataaaga aattatctgt cctataacaa caagtataaa
     6901 atcacgatta aaaagttttt tttctgcttg cataaaatct ctccttttta tttaatcaaa
     6961 cagaccgtcg gtttatataa tggtttaaat aaactgctct tttatagagc agtctatcgt
     7021 atagggataa caaatacagt tatttacaaa actgtataaa tgcagaaatt gtttcttcgt
     7081 ctaataatgt gtctatgcct attccattta aaagggcatt gaatgtattg caacgttttt
     7141 ccataccctc tttatccgtc atttcaacta atgggttgag ccatacatta cttaatacca
     7201 tgataacttc tgcaatttca tgtgaatttt caatctccaa agacttatcc ttgatacctt
     7261 gttctaaaac gggttcaaca aattcaggta ctacaatttc atacatttgt tctatttgca
     7321 tagcaagaaa acgaggattg tttaatagtt gaggagaaac tgtcaataaa acgctttggt
     7381 tagaattgaa taccgctgtc ttaaatattt ctcttaactt ttctaaaccg tttaaactat
     7441 cgttatctct aattttagca aatattactg cattttcatt tccaattctt tgaaaaattg
     7501 cttttaaaat atcttccttt gaatcgaaat gatgataaat agcaccttta gaaagttttg
     7561 tttcattgat aatatcttgc aatgatgtgt tatcatatcc tttttcacaa aacatttttg
     7621 tagaaacatc taaaatgagt tttactgttt cttctggata tttatttcgt gccataactt
     7681 acctccaata caaaccgttg gtctgattaa agtatatctt agtattttat gcttgtcaat
     7741 ataaagactt gcaattttat aaaaatgcag aatgcaagcc tttttcattt attctacaat
     7801 cttccagttg ctttccttat gcggtgtcaa ttcatactgt gatacctgcg ttgcctttgc
     7861 ctgatttacc acaaatcaga ttttatccct ttcttcctct tgattgccca caacagaaaa
     7921 gaaaaagccc tgtcaagagc tttgccacca ttggtggtgc tttgcactct tgatcgggct
     7981 ttttgtttgc tgtatcttct cgcaagagga aaaaagttac tcgtcctcat catcaaaatt
     8041 gttattcctt aatacttctc gtaacagttc catatcttct tttgagttcg ggtttatcat
     8101 tttcacgact tgataaggtg tcttatactt atgtccctct atgctttccc caaacatatc
     8161 catactgtat aaatcatcat agcggtctaa taatttttga aacttcaaat gctggataaa
     8221 ttctttgatt gggtaaaggt cggacgcttc aatgcttttc ccgttgatat agtctgtaat
     8281 atattcccgt aacttttcta actcatattc cagccattct tcctcgctgt caaagaagtt
     8341 atcatagtgt ccatgtttca gttctgcatt tagacgttct tcggctctta aaaactgaca
     8401 gacttccttt tcagattgat tgacatactt ccattctccc gacaacaatt cattgggcgt
     8461 aacgtccagc acttccatta tcttttccag cgtttcatag gcaggatagt tcaaccctct
     8521 ttcaatcttg gaaaggctct gcatattgat accgattttg tccgcaagtt cctgttgttt
     8581 cattccccta aattttctta tggtctgtat attatttcct aaatggctta ttttcattgc
     8641 ataaccctcc atatctcgtt atatcttcgc tattataagt ctatcatgct taatatgatt
     8701 tgtaaaggca aaaaaagata ttgacaaata agcatataag aattactatg ttcttgtaat
     8761 cgaataagca caatagaatg aaatataaaa acattcaaaa agaaatacct atctgattaa
     8821 atccgtagat atgaatatcg gttgaaatgg aacttgttag aaaaggcaaa acagaacttg
     8881 ctgacaaagt atttctgaca cggtggcgga agcctctcag gcttaccgcc atgacacctt
     8941 gtgtcaaggg gaagaaatgc tttgtcggct ggcgagcctg cgagccttgt ctgtgccccc
     9001 gttatctaac aggggggcac tatttcacaa aagacaagtc aaaaaccata cacccccaaa
     9061 cctgtgagta gtaatgagag gttttaagaa gatagtacat atcacacttt ttgaaaggtg
     9121 gtttacaggt atttcaaggc tattgtggga ttggaggaat acaatgaaca atttagaatt
     9181 tgcacttgaa atgaagaaca aacgtcttgc cagcggtctt tcacaaggag aacttgcaag
     9241 tcttacccat gtatcaagat atagtatcaa ccgctttgag aacggaaaag ctaacgccag
     9301 caaggaaaca cagaacatta tcctgcgttg tctgaattac tatatctgcg ataagccttt
     9361 ttatctgctc gttgattatc tgtctgtccg ttttccaacg actgacgcat tggaagttat
     9421 ccgaaaggtg cttggcatga aagcagatta ttttatccat tatgactatg ggtattatgg
     9481 ctataaggag cattatgctt acggggaaat caaggtcatg gcttctgatg atgaacacat
     9541 gggcgtattt ttagaattaa aaggggcagg ctcacgcaac atggaatatg tcttacaggc
     9601 acagaacagg gactggtatt cattcttaaa ccgctgtctt gactgtggcg gtgttatccg
     9661 acgttttgac ttggcaatca atgatatgtg cggtctgctg gatattcctg tgctatctga
     9721 aaaatacaga aatggtggtg cggaatgtcg ctgtaaaaac tatgaaaatg tacaaggtgg
     9781 aaaattaagc ggaaaaaacc gtaatttagc aagtaccctt tatatcggct caaaggcaag
     9841 cacaaaatat ttctgcctgt atgaaaaaca aaaggaacag gcaacgaaaa agaaacatac
     9901 cgatattatc aaccgttttg aaattcgtct gcgtgacaaa aaggcggtac aggcagttga
     9961 agaactgtta ttgacgtata accctcatgg gctggtgttt tatctcatta ccgattttgt
    10021 ggaatttcct gactatccat tgtgggagat attcatttcc catgacagtt taccttttga
    10081 aatgaaccct gtacctgtca atatggaacg cactctgcaa tggctggaaa gacaggtcat
    10141 gccgtcaatc gtgatgatag aggaaatcga caggctgaca ggttcaaact acatgaaaat
    10201 gattgatgaa tgtacccacc tttctgaaaa acaggaaatg cttgtggaac agatgtgtac
    10261 ggacatatca gacgtaatcg aaagtgaggg ggtgttttat gagtaataca caggatattc
    10321 ccgtatggga aaaatacacc cttaccattg aagaagcgtc aaagtatttc cgcattggag
    10381 aaaacaagtt aagacgattg gcagaggaaa acaaggacgc tggctggctc attatgaatg
    10441 gcaaccgcat acagattaaa cgccgacagt ttgaaaaggt tattgataaa ttggacgcaa
    10501 tctaatgcaa atgagccttg tatgtgttat gatgaacaca agtcatatca aggctctttc
    10561 caacaaggaa aggagcagac accatgaaag aaaaaagacg ggataacaaa ggtcgtatcc
    10621 tgcatactgg agagagccaa cgaacagacg gaaaatactt atataaatat gtagacgcat
    10681 tgggaaacac aaaatatgtg tatgcttgga gattgacacc cacagacccg acaccaaagg
    10741 gaaaacggga aaaaccctca cttcgagaac tggaacagca gataagacgg gatattgagg
    10801 acggtatcga cagcacaggc aagaaaatga cgctttgcca actctatgcc aaacagaacg
    10861 cacagaggac aaatgtgaag aaaagcacac agaaacaacg ggaacaactc atgcggttat
    10921 taaaagagga caagttaggt gctaggagca ttgatacgat aaaaccctct gacgctaaag
    10981 aatgggcgtt acgcatgaaa gacaaaggct tttcctacaa taccattaac aaccataaac
    11041 gctcgttaaa agcgtcattc tacatagcca tacaagatga ttatgtgagg aaaaaccctt
    11101 ttgatttcaa gctaagtgaa gtcatagaaa atgataccaa agagaaagtc gcattgacag
    11161 aggaacagga gcaagcctta ttgtcattta ttaagacgga caacgtgtat cacaagcatt
    11221 atgatgatgt gctgatactg ttaaagacag gacttcgtat ctcggaactg tgcggactga
    11281 cagtagccga cattgatttc aagaatgaag ttgtgattat cgaccaccag ttactaaaga
    11341 gtaaggaaca gggctattat attgaaacgc ctaagacgaa aagcgggata aggcaagtgc
    11401 cattaagcaa agaaacgata caggcatttc aacgggttat caacagccga ccaaagataa
    11461 agtcgataga ggtagacgga cacagcggtt ttgtgtttat caatccgaaa ggtaatccaa
    11521 aagttgccat tgattataac gccttattta tccgtatggt aaagaaatac aacaagcacc
    11581 acaaggacaa tcccttgcca catattacac cgcatacgct acgccataca ttctgcacaa
    11641 ggctggcaag caagaacatg aacccgaaag atttacagta tatcatgggg cattcaaaca
    11701 tcagtatcac aatgaactgg tacgctcatg cgtccataga taccgcaaaa tcagaggttc
    11761 agcgtctaat cgcatagaag tatttaccac gattttaacc acgattgaca gggaaaatat
    11821 aagaagatag acctagatat gcgaggttta ccacaaaagc aaaatgcccg tagagccgat
    11881 aaaataaggc tttgcggaca tttgagaaga tataaaaaga tagtcaaaaa gacatatata
    11941 atttataata attatgactc ttaattaaag taggtgccca tatgcttgtt tcttttagta
    12001 tggttataag attttttctg acaattttat tatcactgat attaacacct gtattcaaaa
    12061 tcatttcagt acaaacaggt atggtcgaca aaccaaatga aagaagaata aataaagttc
    12121 caatgccttc agcgggcgga ctgcctatct ttatttcatt tgttatatcg actttattct
    12181 tattccgtaa aattatccct caatcgtata ttgtaccgat cttgattgct tctttagtaa
    12241 tcatagtcac aggagtgctc gatgataaat atgagctgac acctaaacaa aaaagtatag
    12301 ggatcttgat tgcttctctt attatttatt ttgtagcaga tatacgtatt gattccttca
    12361 cgcttccttt tattggatat atccaactag gctggcttag ttttcccgta acgatttttt
    12421 ggatcttcgg tatcacgaat gcggtcaatc tgattgacgg tttggatggg ctggcggcag
    12481 ggatttcatt gatcggttta attacgatag gaatcattgg atattttttc ctccatgctt
    12541 ctacagtgta tattccagtt gttattttct gtcttgtagc aagtattatc ggtttttttc
    12601 cttacaattt ttatccggca aagatttatt taggcgatac aggagctcta ttcctagggt
    12661 ttatgatggc cgtcctttca ctacaagggc tgaagaacgt gacttttgtt tcatcgattt
    12721 ctttgctgat cgtcatggga gtgccggtaa cagacacgtt ttttgctatc attaggagaa
    12781 aagcaaaccg tgtttctttt tctacagcag ataaaaaaca tcttcatcac cgactaatca
    12841 gtttaggctt tactcataaa ggtgctgtcc tgacgattta tgcgatggct ttgatgtttt
    12901 ctttcacagc tatggtcatg aattatactg gaagaatcgg aacgatcata ttgattattg
    12961 ccatgttgtt tgctgcaatt ttattatttg aattgattgg tctgatcaat gagaaacatc
    13021 agtttatttt aaaaacattg cgatttttag ggaataaaga gtaccgtacg caagtaaaac
    13081 agaaatattt gaagaaatgg aaccgtcata tagatgaata acaaattaaa ccagccgatc
    13141 cttattagta ttgtgacggc aaacagtgat aaaatttttc ggacactaga taattttatt
    13201 tcaactgtaa aagatgaaac agcagtaaaa atccgaattt ttgacaacaa ttcacttccc
    13261 gagtacaaaa aaagactaac agagtatagg aaatatccct acatcgatat ctattttcat
    13321 gatgaaaatt ccggatttgg ttatggacat aatcacaatc tgatagctag cgattctcgc
    13381 tatggcatta tttgtaaccc agatatttta gtggatgaag agacagttac agcattggtc
    13441 ttgttattga aagaacatcc ggaatgtgcg atgttagcac ctaagattct taatgaagat
    13501 ggaacaactc agcacctcat ccgtgagcag ctggctgttt ttgattacgt tttgcgcttt
    13561 gtgcctttca aatgggtcaa aaaaaagttt gacaaacgac tggctgtgtt tgaatgccga
    13621 ggattgccta ctgatgctaa tagttatgta cggatgatct caggtagttt tatggtagct
    13681 gatattgata aatttaaaga gataaagggg tttgatgagc gtttcttcat gtactttgaa
    13741 gacaacgact tgtgtttgag ttttgaaaaa gcaggttaca agttattgta cacacccttt
    13801 tatgcagtta tccattttta cgggaagggt gcgcatcgaa atgcaaaact gtttcgcgtg
    13861 tttttgactt ctatgatgaa atttttcaat aagtgggggt ggcgtttttt ctgatgaaac
    13921 cagaaatatt agtagtcgtt gtgctttatc agcaactatt cagtcaatct ccagcttatg
    13981 gaccattaag caaagcactt agcgaaaagc aaattcagct tattatttac gataatagtc
    14041 ctcaaaggca gcaaaatgag ctgtttgaaa aagaaaatat cgtttatcat catgatccgc
    14101 aaaatcctgg tttagcggtg gcttataatt ttgcgttgtc tcaagcagat gaaggaacac
    14161 gttgtctcgt cactctggat caggatacga ggctagtcga cgattatttt gaactattgc
    14221 gtaaagtaac ctttacagat gaatgtgttg ctgcagttcc gatgattttt tctgggagcc
    14281 gacaagtttc tcccctatat tcagatcgtt atatcaatcg tacagctcaa gcagtagaag
    14341 ttgaaggccc aacagctgaa cgaatcatgg caatcaattc aggtgttgcc tggtctgtca
    14401 aatttctaaa aaagattggc gggtttaatc ctgctttttc tttagatttt ttggatcatt
    14461 ggctgttttg gaaagtggat cagttggaaa aaactgtgga gatccttcct gtacgaatgg
    14521 aacatgatct ttcggtttta gactatgaaa aagtttcaag taatcgatac cgttctattt
    14581 tacaagcaga aaatcgattt tatcatgaat atgatcaaag gcatttatcc agtcaccgac
    14641 gacaattatt gttaagaaca gctaaacagt tcttgaccgt caaaaaccgg catatctggc
    14701 ggatgacttt gcgctcatat gttaagaatt ggaaggtgtg aattcgtgcg ttcggtttgt
    14761 atagctacct ttaatggagg cagatattta agagagcagt tagatagtat tttatctcag
    14821 ctttcagcag aagatgaagt agtcatttct gatgatgggt cagtagatga tacatgggat
    14881 atattaactg aatacgcaga aaaagataag cgaatccagc ttttttcggg gcctcgtcaa
    14941 ggattgatcg ctaattttgg ttatgcgatc cagcagacga aaggagatct aatctttttg
    15001 gcagaccaag atgatgtttg gttggagaca aaagtgaaaa agatcactga ctattttgag
    15061 cagaatccgg atcagctagt agtagtttct gatttaatca ttgtggacag cgagctgcaa
    15121 gagatccatg attcgtattt ttcgtttcga aattccaaag aaggatggct taataatgtg
    15181 ataagaagtc actatattgg tgctggtatg gctttccggt cttctttaaa acccgatatt
    15241 ttgccgatcc cgtcagaagt gccgatgcat gatatgtgga ttggtttgct gggaggaaag
    15301 aagactgggt tcctaagaga accgttaact ctgtaccgaa gacatgattt aaacgcgagt
    15361 gagattgaaa cacattctaa attacggcaa aaaatttctt ggcgtgttca tctgattacg
    15421 gcgttgatca aacgaaaatg gtttaaacgt tgataaaaga tgtttaaatc cttaatattt
    15481 ccatgacaaa tataacaatt gatgagataa taacaaagtg aaatttgaaa tcaaaaagga
    15541 gagcagatat ccatgaaggg aatcattctt gctgggggca gcggaacacg tctgtaccct
    15601 ttaacaaagg caacatcgaa acaattgatg ccgatttatg acaaaccaat gatttattat
    15661 ccaatgtcta ctctgatgtt ggcgggaatc aaagaaattc tgattatttc aacgccacaa
    15721 gatacaccac gtttcaagga attatttgga aacggaaatg atttaggact gcagatcgaa
    15781 tatgcagtac aagaaagtcc agatggattg gcacaagcgt ttatcattgg agaagaattt
    15841 attggagatg atagtgtctg cttggtatta ggggacaata tttactatgg tggcggtctg
    15901 tctaaaatgt tgcaacgagc agcttcaaaa gatacaggcg cgacagtatt tggctatcat
    15961 gtcaatgatc cagaacgctt tggtgtagta gaatttgatg agaatatgca agctttgtcg
    16021 attgaagaaa agcctgctca gccaaaatca aattacgctg taactggcct ttatttttat
    16081 gacaatgagg taatttctat cgctaaaggt atcaaacctt cagaacgtgg agaactagag
    16141 attacggatg tcaataaagc atatttggat aaaggaaaac tatccgtaga acttatggga
    16201 cgcggatttg cttggcttga tacaggaaca catgaatcat tgcttgaagc atctaccttt
    16261 atcgaaacaa ttgaaaaacg tcagaactta aaagtggctt gtttggaaga aattgcttac
    16321 cgtatgggct acatcgataa ggaacaattg ctggcccttg cacagccatt gaaaaaaaat
    16381 caatacggtc aatatttatt gaatttggcc gctgaataag gagtccttac agatgaaagt
    16441 aacagataca aaattaacag atgtcaaaat cgtagaaatg gacgtctttg gcgatcatcg
    16501 cggtttcttc acagaaagtt attcaaaagc aaaatttgca gaacatggat tgaaatatga
    16561 ctttgttcaa gacaaccatt cactatcagc tgaagctggt gtccttcggg ggcttcattt
    16621 ccaaaaagga gaagctgcac agacaaaatt gattcgggta gtcactggag cagttttaga
    16681 tgtagtagtg gatatccgca aaggtagccc gacttatggt caatgggacg gatttatctt
    16741 atctgaacat aatcatcgac agttgcttgt acctaaagga tatgcccatg gattcgttac
    16801 tttgacacca aatgtgaact tcctttataa gtgtgataat tactataatg cagaagcaga
    16861 tgggggcatc gcatttgatg atccagattt agcgattgat tggccaattg atccatcaag
    16921 agcgattatg tcggaaaaag atcaccgtca tccgacatta aaagaatttg aagcagaaaa
    16981 tccatttgtt tacggagaaa tctaagaatt aaggagaaat tttcttatga aaaacatcat
    17041 tgttaccgga ggtgccggat tcatcggctc taatttcgtt cattacgtgg taaacaatca
    17101 tccagaagtg catgtcactg ttttggataa actgacttat gcaggaaaca aagagaactt
    17161 ggctggactt cctagcgatc gcgtagaatt ggtcgtagga gatgttgcag atgcagaatt
    17221 agtggaccgt ctagtaaaag aagcggacgc agttgttcat tacgcggcag aatcccataa
    17281 cgataattca ttaaaagatc ctttcccatt tgtacaaacg aatatcattg gtacgtatac
    17341 acttttagaa gcttgccgca agtatgatgt acgctatcat cacgtatcta ctgacgaggt
    17401 ttacggcgat cttccattac gtgaagacct gccaggacat ggggaaggcg aaggagaaaa
    17461 attcactgcg gaaacaccat ataatccttc aagtccatat tcttctacaa aagctggttc
    17521 agatctgtta gtaaaagcat gggtgcgttc ttttggctta cgtgcaacca tttcaaactg
    17581 ttcaaacaac tatggtcctt atcagcatat tgaaaaattt attcctcgcc aagtaacgaa
    17641 tatcttaagc ggtattcgtc caaaattata tggcgaagga aagaatgttc gtgactggat
    17701 ccatacgaat gatcattctt cagcagtgtg gctgattttg acgaaaggca gaattggcga
    17761 aacctatctg atcggtgcag acggtgaaga agataataag accgtgatgg aattgatctt
    17821 agaaatgatg ggtcaaccaa aagatgcgta cgaccatgta aacgaccgtg caggacacga
    17881 cttgcgttat gcaatcgatt cgacaaaatt acgggaagag ttaggatgga agcctgagtt
    17941 tacgaacttc cgtgatgggt tggctgacac gatcaaatgg tacgaagaac atgaagactg
    18001 gtggaaaaaa gaaaaagagg ccgttgaagc agcatatgcc aaaaatggac aataatacag
    18061 agaaaatgtc actgtattaa tggaaaaaca catgtgaggc aggcgctcgc ctgtctcttt
    18121 tttaaaataa aaatcaagga gcggataatc atatgttttt attaactgga ggaaatgggc
    18181 aactaggtac agaattgcgc catttattag atgaaaaaaa tctgcaatat gtttcaacag
    18241 atgcaaaaga cttggatatc acagatgccg agaaaacaat ggcttacatc acagaattaa
    18301 aacctgatgt tattttccat tgtgcagctt acacagcagt agataaagca gaagaagaag
    18361 caaaagaatt agatgagaag atcaatgttg atggtacaag aaatgtagca cttgcagcaa
    18421 aagctgtgaa tgctcaattc gtctatatca gtacagacta tgttttcgat ggaaaaaaca
    18481 aaaatgtaga atacgaagta gacgaccaaa cgaatccact aaatgaatat ggtcgtacga
    18541 aattattagg cgaaaaagca gtagaagaga ttttagaaga ctattatatc atacgaactt
    18601 cttgggtttt cgggatctat ggacacaatt tcgtcttcac gatgcaacgc ctagcggaaa
    18661 cccgcgacaa actgactgta gtaaatgacc agtttgggcg accaacttgg acacgtactt
    18721 tggcagaatt tatggtatat gtcatcgaag aaaaagcacc atttggtatt tatcatttgt
    18781 cgaacgaaaa tagctgttct tggtatgaat tcgcaaaaga aatattgaaa gatacagatg
    18841 tagaagttgc acctgttacg tcagaagaat ttccgcaaaa agcaacacgt ccgcagtatt
    18901 cagtcatgag cctgaaaaag acagaagagt taggatttgt cataccaact tggcaagaag
    18961 cacttgcgca aatgctggaa gctgccaaaa aaatgaataa gtaatttcct tttatcaaat
    19021 agaatttgga gcatgatatg gaaaaacaaa caagaagtgc acgacgaaaa gaaaagccaa
    19081 aagcgaacca ggcagattcg aatttggtgc ttgacctgtt tctaaaactc cgctatctta
    19141 ttggcgtttt agtcatcgtg gtcatcgtta cttttaattt aaacggaagt tcacttggtg
    19201 tttgggataa atatgtgtcg caaagagacg atgggaaaaa aactgatgtg atttttggac
    19261 agaatcggga agtgcggtca gacgaatggc tggtgcagac acctttttac ctctcacaag
    19321 ctgaagagga ctttccgttg gtgaacgagg attattcatt aaacggacaa aacatgatca
    19381 ttgcgtataa ttctcctgta aaggatatta cggttatcgg aaaaccattc aactggggat
    19441 tctttttcct cggaagagat cgaggacttt ccttttattg ggcgatgaaa ttagtcgtca
    19501 tggtcttgct tggattcgaa gtactgatga tattaacgaa gagaaaaaaa gctctatcgc
    19561 taatcggtgc atttgcgctg acattttctc cagcagtcca gtggtggttc atgcaacatg
    19621 tgggcgattt gattttcttt actttgggac tgatgactgc tttttatcat tatttctaca
    19681 atcatgataa aaaatggcta cgaacgttga tgatgctttt ggtggttatt ttcggtattg
    19741 ggtttatttt agtgatttac ccagcccatc aagtgatgct ggcgtacttg ctgatttttt
    19801 attttgttgg cctgcttatt tactatagca agaaagtttc atgggatctg ttggatgtag
    19861 tgttgattgg aggggcagtt ttatttattg gcggagtcat ggttcatttc tggctaacgt
    19921 caaaagacgc attgttagct tctttgaata ccttatatcc aggaaaacgg gtaagtactg
    19981 gaggaaagtg gacgattggc gaattttttt ctttccttac aaattggaaa attccttttg
    20041 aagatatcaa ctattcgaat aactctgaag tggccctgtt ctatcacttt tttccaactg
    20101 tattcctagc aagtccattt gtgttatttg gcaaaaaaga tagcgaacaa aagttactgg
    20161 gacgtatttt gatgattttt tgtctgtttt ctatcttttg gattaccgtt gggttgccaa
    20221 aatggctagc agaaatcact ctgctgtctt atgttcctcc attaagagcc atccttactt
    20281 ttagttttgc ggcttgttta ttatcgatct ggtttatcgc ttatatttgg agagaagatg
    20341 ttattcctat ttggtataaa ttcattttgt tggcagtaaa tgcatggtct tatttctatg
    20401 cgattacgca ttcgaaaatg gataattatt tttcggattt tgaaaccatc gcagttgctg
    20461 tgttgggaac agtgatttta gcttttgcat tatttggctg gagacgcttg ttttacctcg
    20521 cttttgccgc cttagttatc gtatctggct ttttcgtcaa tccagtcgta gaaggtacag
    20581 gagcgatttt tgaaaaaaca ctggcaaaag aaatccaaaa aatcgatcaa caagatcctg
    20641 gtaaagtttg gttgtctgaa gatgaattat ataacttcac cccaacattg ggagtgaaat
    20701 ccttcaatac agtacgcttt tatccagata tagctgcatg gaagaaaatc gatccgaaag
    20761 aagaatacga gaagtattat aatcggtatg ctcatacaag agcttttatc gctaaggaag
    20821 atacaaagtt cattttagat cgtccagata tgttttcggt cacgttgaat tttgaagacg
    20881 cagaaaaatt agggatcgac tatgtgatca gtaaacgacc attaactgat tacaaccaat
    20941 tatatgaagc gcagttcacg cagctatatg gaccggataa agacggttat atgattttta
    21001 aagtagaata tccggattat ccagatgtac cacaaacaca aactcaggaa aatcagctag
    21061 tcgtacagta ataggctagc tgagaataat cctgaaatgt tagtagaaag gagagtggag
    21121 ataattcaag caatcgtaca aaaatttgtc aacaaaatga gtgtcggttt cttgcttttg
    21181 ttactgacgc tagtcttttt tgtttggaca gcagggttag gttttccagc aactttgttt
    21241 atatataaca atagttcatt acttatcgct tttagtgtgg ctattttgct cattttaaat
    21301 gtttataaag caaaaggcgt cgattttctt tatctaggtg ttgcgcttgc ccttttcatt
    21361 ttcttttctt actttcggga attaagaaat gagtctttat ttggagactt actgtttcct
    21421 ttgattattt tattttgttt agtaattaaa tggatcgagt ggacaaaatg ggatcgcggt
    21481 atttatctga ttgtcttttc ggtcttcctc ggaatcacgt tatatcgtgt atttacagag
    21541 atccaagtac cagaaggaca aagcatctgg gctccaggca attcgctttc tgatatttgg
    21601 atcaatacga atataatcgg aagttctttg atgactcttg ctttattgat cagtggattt
    21661 gccagttctt ttgaacgatg gtatgtacga atcatcggtg cagtagcagt tgttgcagct
    21721 tttctcggga tttgggtctg ccaatctaga ggtgcattag tcgcgttgat tgtttttgcg
    21781 atattggatc ttttacctaa atcgttgatg cgtgtcattc gtgcgccatt tattgcttac
    21841 acggttacga ttcttttagc tttgccgatt tcttatctgg cggctgtctc tgaaaaagtc
    21901 aatttgttta ccggtcgaga agatatttgg cataaattct atcagacgct aggagaaaaa
    21961 tctgaacaaa ttttactagg aatgaaaaca tttatcttcc aacgaggaaa ccaattttta
    22021 ggaaaccaca atagttataa ttctattttg aatatctatg gattgatagg atttgggatt
    22081 gctgctttgc tgcttatcct ttttattggt cgcttaacgt tgaaagcaga tttatccaac
    22141 gggcagatga cttttatctg ggcctttttt gcggtgatga tgcagtcatt tatggaggat
    22201 acattgactt catacccatg ggttccgatt atttatatcc tgttggctat ggccgttcat
    22261 cgatatgatg aaccagaagt tgcggaggaa ttctatgtta tggaagaggc atatgacgat
    22321 atgacttatg atgatacatc ttatgaggaa caaccagata gcgctcattc ttccaggatc
    22381 caacgctatc attgataggc acaaaatacg agagaggctg tgacaaccgt cgcagccttt
    22441 tttggtttat tgcaattgtc tagcatcttc tgtaaaatag aaacgttaga gaaaatcttg
    22501 tatcatagaa aattaagaaa gaaataagaa cgcagctcgg taccaaaaat atggtaaaat
    22561 ggcacttgac tgtaattcac tgaaaatcgc ttggaggaac acaaatgttt aaagatttgt
    22621 atttatttat gaaggacatt tatcagaaca gaaaattatt gctacagttt tcgatcaatg
    22681 acttcaaatc aagatatgca ggatcgtttt taggaatctt atgggcgttt atcaatccgc
    22741 tatttactgt attgatttat tggctggtat ttggtgttgg actgaaagca caaatgatcg
    22801 atgcaaaata cccatttatc gtatatttag ttaccgggat gattccctgg ttcttcttct
    22861 cagatgcatt tgcatcaact acggttgttt ttcgggaata tacttattta gtaaagaaag
    22921 tcgtattcaa tattcgtatc ttgcccacga cgaaaatcct atccaatctg tacacccact
    22981 tattcttcat tctgattggc atagctgtcg cgcttataaa tggtatatat ccttcagcaa
    23041 tgtctttaca gctgatttat tatttatttt gcatgtgtgc tttcttgaca ggattgactt
    23101 ggctgacggc atcgatccaa ccatttttac ctgatatcat gcaattaatt acgatcgtgc
    23161 tgcagttgat catgtggaca ttaccgatat tatggagccc taatcagttt gattcaggtc
    23221 ttgtaagcat attgaaatta aatccgctgt actatgttgt tcaaggttat cgtgagtcat
    23281 ttttaagtga agcttggttc tgggagcatg gaacatatac tttgtatttc tgggttttca
    23341 cgttagtaat gttcgtaatc ggctctgcag tgttccgtag attgaaacca catttttcag
    23401 atgtgctgta aggagaatag ctatgacaga atatgcaatt agactaaaag atatcacaaa
    23461 atcttataat atgtacgcaa aaccttcgga tcgatttcgt gaagccctca atccttttaa
    23521 gaaatcctat catgatgtat tttatgcgtt gaaaaacgtg aatgtagaaa taaaaaaagg
    23581 tgagatgatc ggtttcgtgg gagaaaacgg atcgggaaaa tctacaatgt tgaaaatcat
    23641 tacgggagta ctgacaccaa catccggcac gatggaaatc gaaggaaaaa tctcagcttt
    23701 gctagaacta ggatcaggat tcaatcctga gtattctggc tatgaaaata tctatttaaa
    23761 tggaatggtt ctaggatttt caagagaaga agtcgatgaa atggtcgatg atatcattga
    23821 atttgctgac atcggagacc atatttatca acctgtaaaa acttattcaa gcgggatgtt
    23881 cgttcgtcta gcttttgctg tagcaatcaa tgtgaatccc gatattttga ttgtggatga
    23941 agcattggca gtaggcgatc ttgaatttca actaaaatgt atggaaaaat ttacagaaat
    24001 caagaactcg ggaaagacga ttttattcgt ttctcatgat atcagttcga ttcgtcgttt
    24061 ttgtgatcgt tcctattggt tgaaaaacgg agaagtcgtc gaatatggcg atacgatgga
    24121 agtaacgacg aattatgaaa actttttaaa gaaaaaatca gttaaaacag tggatcggaa
    24181 taaaaaccaa gtagaacggt tcgccgctcc agatatcgtc gacgtgacga aagcggaatt
    24241 gttggataaa gacaaaaatc cggtggatat gctggaacaa ggagaaaaac tatacgttaa
    24301 agtaacttat gaagtaaaag atgatacaat caaaaatccg gttttaggaa ttgcgctacg
    24361 aacagtcgac aatttttatg tatgcggact taatactcta ctagatggta tcaagattcc
    24421 ttggaaaaaa ggagagaata tcttttatct ggagtatgaa aagttaggtt tgttagctgg
    24481 tgaatattat tttgacgttg cggtctttga agaaaatgca acggttcctt tggtatataa
    24541 gacaaagtac atgaacttgt ttgtcagcgg ttcttatatc ggagaaggca tcgtggtctt
    24601 agaccataaa tgggaagaag ggactcatag caatgaaata tgattttgaa atggacctag
    24661 atgaacaaag cagtgtggga aaaattgccg cacagatcaa accaggaagt aaagttttag
    24721 agtttggtcc cggaaacggc cgattaacga aacatttaat cggagcaaaa caatgtgaag
    24781 tgagcattgt tgagttagat aaggaattgt tcgattttgt cagcgaattt gctcaagatg
    24841 gattttatgg tgatatcgaa agttttgagt gggcaaacta ttatgctgga cagacatttg
    24901 attacgtctt gtttgcggat gttttagaac atttggtaga tcctggaaaa acattgaaga
    24961 aagtcagaga atttttgaat gaagaaggag agatcctgat tacattccct aacttggcgc
    25021 ataattctgt catgatcgat ttgttcaata accaattgcc gtgggcttct tatggtctcc
    25081 tagatgaaac ccataattct ttttatactc atgatggctt ccaaaaagtt tttgaaaaag
    25141 cgggattatt cattaatatt gaagattatt tgtacttagc tgtaggtgat acagaattaa
    25201 aatcaactta tgaagaattg ccggaagctg tacgctatga tttcaaaatg cgaccatttg
    25261 gtgaagtcta ccaatacttt ttctcattga tgaaacatcc agtagcacaa agttccattg
    25321 cagagccaca aaattctaat tatgtaaaag tgttagaagt aacccagcaa acgaaacaag
    25381 atgaaacaat ccaacaaata ccattcaata atttcacagg ggaaaatgag acactaagtt
    25441 tccccgtatc agaaacaaca gaaagaatgg tgtttcgctt cgcgcaacaa cctagcttta
    25501 tcgaattcag cgcagaagct gccggagaaa aactaacatt tatcgattcg aatgctgtag
    25561 tcaaaacagt aaatgattgt tatttgtttg atgggaaaga attaccagag ttcgttctaa
    25621 cggatatttc tgggaaagaa gtgactatcc attgtcacta tcgctttatc ggggaattga
    25681 caccaacaat gaaagaattg ttggaaacga ttcgtcccat ggctgaagtc acaaagcagc
    25741 tttctgagaa aaatgacgaa ttagaaagag aaaatcatca tcttcttgag gaaaatacaa
    25801 gactagacca tacgttaaaa acaaccacaa atcgctattg cacattgttg gaaagtgatg
    25861 aatggacaat aaaacataga ctaggacgac gtaagaaaga aacttcgaaa aaaatccaag
    25921 aaaaagaact ttctatatgt attgacgaga aaatctggga tgcagaaaca aaaatattaa
    25981 aaatcatcgg atggggaatc gctaattcgg atcgccagcc cttgtcctat aagttatcag
    26041 ctgaccaatc gccatttttc gaagcaattc ctgtttcacg agaagaagtc aatcaagcag
    26101 aacagctcgc aaaaggaaca gaagcgggat ttgagttacg aatcctttgc gagcaagaac
    26161 gttcattctt agtggaagca gtagctcaaa atggccaatc atggatcatt gaaatgtaaa
    26221 taatgattaa cttataaaga taaggagtaa acgaatcgtg caaaaaaaag aaattgccgt
    26281 atttatcgat caaatcactc gtgaacgggc cactggcgat ttgcttattg tgggctgggc
    26341 aattgatgaa gtgaccaaag aaatccctac gataaaggta gaaaaagaaa atgtgattgc
    26401 tgaagcaaca catgtcgtaa gattggatat caatcattta tataatcttg atgttaagac
    26461 ccaaagcggt tttaaggtac gtttatcagg gaaaatgaga ggaaaagcca tcttagactt
    26521 ccaaacagcg agacatcaaa atggcatagc tgtgaaatta aacggtaaat acccttatga
    26581 tgacggcatt gaatcttcat gggaaagaaa aaaaagatta ctgaaaaaag ggataaatta
    26641 tgcaaggact catggcgtaa aaaaagcgat ccgtcgggtc aaattggaat tgaagccagg
    26701 atcgatcgac tatgcagagt ggatcagtcg tcatgagaaa ccagatttga aagagcaaag
    26761 gaaagaagca caaggatttg cgtaccgtcc attgatttcc atacttatgc ctgtctataa
    26821 cgttgaaatc aaatggctcg aaaaatgcat tgattcggta ctggatcaaa cgtatgatca
    26881 ttgggaacta tgtatcagtg atgatgcttc tactgatcca gctatccgaa agtgtctgga
    26941 atcctatcaa gcaaaagatg atagaatcaa agtcgttttc cgaaaagaaa atggacacat
    27001 cagtctggca actaattctg cattggaaat agcagaagga gaatttatag cactcttaga
    27061 taatgatgat gaattaccgc catttgcatt atatgaagtg gcaaaagtgc taaacgtaca
    27121 tccagaactg gatgtgatct acagtgacga agataaaatc gatgcagatg gcaatcgctt
    27181 tgatccgcat ttcaaagcag actggtcgcc tgatacattg atgggaaata attatatctc
    27241 tcacttaggc gtatatcgaa caagcattgt taaagaactt ggcggtttcc gtaaaggcta
    27301 tgaaggttct caagattatg atttggtcct tcgtgtgaca gaacaaatcc ctgcagatca
    27361 tatttaccac attgaccgag tcttgtatca ttggcggacg atcccaggat caactgcaag
    27421 taatggcgaa gccaaaagtt atatctatga ttccggagtg aaagcattga cagatgccct
    27481 gtctagaaga aacatcaaag gaagcgtatg tcctggcaga atttctggat tttatgagat
    27541 tgcttatgac gtcttgcaag aggatttggt cagtgtgatc attccaacga agaatggcta
    27601 tgaagatcta aaaacttgtg tggattcgat catcgaaaaa acgtcttatt caaattatga
    27661 aatcattatt gcggataacg gaagtacaga tccaaaaatg caagaattat ttgcagaata
    27721 caagcatcag ctgaaagacc gctttatcgt agaattgatt gacattccat tcaattattc
    27781 tcgaattaac aatttagcag cagaaaaagc aaacggcaaa tactttttat tcttgaataa
    27841 cgatacagaa gtgattgagc cagattggat gacggtgatg gtttcttatg cacagtttga
    27901 tcgaatcggc tgtgtaggag caaaactgtt ttatccagat gatacaacgc agcatgcagg
    27961 agtattatta ggaatcggtg gtgttgcagg gcatgcattg aataactatg atcgaacaca
    28021 ttgtggttat ttcggccgat tggtcattga cgtcaattac ttagcagtca ctgcagcttg
    28081 tatgatggtc aaggcagctg acttcaatgc tgttaacggg tttgatgaaa cattagaagt
    28141 agcattcaac gatgttgact tgtgcttgaa agtttatgaa ctgggtcgtt acaatgtcta
    28201 tgcacatcaa gcagaattgt accatttcga atctaaatca agaggttatg aagatactcc
    28261 agaaaaacaa agacgttttg ctggtgaaat caaaaaaatg caagataaat ggccagcata
    28321 tattgcgcat gatccatttt acaatgataa tttaacaaaa gaaggaatcg gcgacttttc
    28381 gttgagacca gattaaacta taataaaaag ctgttatgtt gtgattcgct cgcacataac
    28441 ggctttttat agttttttgt caaaaaaagg cagaaggtgc cgactcaaaa aaataagtcg
    28501 aggttgggac agaagtgttt aactccgaga aataagaaga aattcacgaa aattgctttt
    28561 caaatttttg tgaatttcgg cttatttaag aagaagttgc ttctgctccc accgtttatt
    28621 cgtttttaaa gaatgagaca aaagtgtttc ttacttttgt cccacgctct tattcatgct
    28681 cagagcgcca atagatacaa aatcatagcc aaagtttcac gaaccctagc tgtcaaagaa
    28741 tcgatatttt attttaatat aggctatttt aaaataaatg gtttaaggta ttcctctaca
    28801 aaagccactc tatcaattat catgggttta aaataagaag tgatggagat aaccagattg
    28861 ttcttagcgt caatataaag aacatttcca ctattaccaa ttgctgaata tatttcgttc
    28921 tcagaatcta atacccacca taaatagcca tatctcatat tttgtaagtc ttctaaagca
    28981 ctggttctag gtttgaacat ctcgtttatc cacatgggtg gtacgatttg ttttccttta
    29041 tacatccctt tatttaggca taatacacca atttttgcca gatcacttgc cgataaacac
    29101 aaaccatatc ctgccgtccc gatatttagt ggatcacaaa accagacatt ggttttagga
    29161 gacttatcca ttgtaaactg cttatgttct tcagctgttt cagcataata attgacatgg
    29221 tttggtatcc ctataggatc aaatagatac ttattggcaa aatcaacagt tgttagctta
    29281 cttgtctgat acaacaagcc agttaatatg tgtaaacaga cagtttgata gttgaattcg
    29341 ccggttatac cttttcttcc tcccaataaa tctagtgatg tttttgtcca atcttcactt
    29401 gaacagactt ttgtccatgg atcgccttta catttgtagg gtgctttcat tgttagcaag
    29461 tgcttgattg taatagcgta aatagttttc tccccgcgtt tcactttata ctctggaaaa
    29521 taatctaata ctttatcatc gatacttttg attaatcctt gctctaaagc aatgccaatc
    29581 agcaaagata caatactttt cgttgctgac atgatatgac aagtatcgtc ttttttataa
    29641 ccattccatt catctgtata aacttctacc ccatccttat atgcgacaat ttgacatata
    29701 tttggttgtc gaaaaccaat aaaatcatgc aactcttgtt tattcataag atattacctc
    29761 actttcttct ataagcataa tgtcattaaa aatcgatttc aattttttcg attcttcacg
    29821 taatacaggt attcttatgg actagacagc gctttgggaa gatggattct ctgaaaaata
    29881 taaaggttca ctttatgagt ggataaaaaa agcagcaaat acttcgactt ctttaattta
    29941 ccaacattag tgaaaatcga ttcatctgga gatttgtaat ttagagtcct tgtcttgatt
    30001 agaggtgtat aaagcttttt attagacatt tttaaattcc attacaattt gcttataaac
    30061 taggttttta aaggtgacta tggtaagata atagagatat tattttgtga ttaggagtgt
    30121 atatatgaat aaaaatggag aatggagtgc tgcacgacgg atattcatta tattaatgga
    30181 tgttattgta tacaatgcag caatatatag tagtttctta ctgaagtttc gtggagagat
    30241 cccattacga aatttagaaa ctttccaaca ctcagcaatt attatttcag tgatttttat
    30301 tgcgttgaac attttgttgg gtgcatatgt tttttataat cgaatgatca gtgacatcgt
    30361 gtttgtcaca gtcatcggtc aggtattgat gacactaggg atcatggtag tgacttttgc
    30421 gggccgctgg tttgcttttc cacgtcttgt tatcttactt tcatttgttc tcggtacgct
    30481 tttcttaagt atctatcgta ttctcgtata taaactttat ttacgcgtaa gtcgagataa
    30541 aaaggtcgtc attattgggt tagaaaagga tgtcgcacca gcaatccaaa attttggttc
    30601 aaagaaaaac aacaaacata aagtcgaagc agtcattctt gataactatt atgcaaacat
    30661 caaaaatatg attaaagaca tcgatattgt ctatcttgct tctcatatcg aagaaactga
    30721 aaaaatcaaa atctatcaat tagttactaa aaatgaaaaa aaattgtttt tgaatacaac
    30781 atttgaaaac ttgacattga tcaatccaaa tattatgaat ttcgaagatg aaagtattat
    30841 tgaagcatct ggatttagaa tccaacctga atatgaacta ttcaaacgtt tgtttgatat
    30901 catcgtttca cttgttttat tagttattgc ttcaccattt atgttattca cagcaatttt
    30961 agtcaaagtg acatcaccgg gaccaatcat ctataaacaa gtgcggatca caaaaaatca
    31021 aaaggaattt tcaatctata aattccgctc gatgaccgcc acagccgaag caaaatctgg
    31081 accagtttta gctaagagca atgatgcacg agtaacgcct gtaggtaaat ttattcgagc
    31141 tgtccgcttt gatgaattac cacaaatctt caatgtgctg aaaggcgata tgtcgatcgt
    31201 aggaccacgt cctgaacgtc ctttcttcgt cgatcagttc aatgcagaaa acccttatta
    31261 ctacttacgg cataatgttc gtgctggtat cactgggtat gcacaagtct atggaaaata
    31321 tgtctctgat tacaacagta aattacgttt tgatttactt tatatcaaaa aatattcatt
    31381 gatgcttgat ttaaagatct tgctgcaaac catcaagatc ctatttgata aaatgtcctc
    31441 tcaaggactt gaagaagacg aaaatgtgat ctcattggca gaaattgctt ttccgaatga
    31501 aaaaatcttt cgctagttgg gaggcgtaaa aatgaacaat ccgaaattca gcataatcgt
    31561 accagtatac aatgcagaag caactattgg tcgaacgatt gatattctaa aagaattgga
    31621 ttatgaagag tacgaagtcg ttttagtaaa tgatggatca acagatcaaa cacaggaaat
    31681 cattcaagaa ctgattgaaa atgatgaacg ttttgaattg attactacga ccaatcaagg
    31741 gcccggatta gcaagaaacg aaggaataag acagtcaaaa ggagaatatc tcttattctt
    31801 cgatgcagat gacacgccag taaaaacgat cttgtcagat tatgatcatt tgctagaaaa
    31861 gagtccaaaa gcggatcttg ttgttagttc gtttgttttt cgtacaatgg acgagggaag
    31921 aatcgtttcc gaaaaagaaa acttagttac agaatgtcac tatctaactc acgaagagtt
    31981 tataaaagac atgtatcagt taatgaatga acagttgatg tatgttgtat ggaacaaatg
    32041 ctatcgtagc gatattctga aaaataacca aattctattt aaaacttata atagttgtga
    32101 ggatcgaata tttaacttac attattatga atactgtcat caagtgatca tgaacccaaa
    32161 agtagaatat atttatgaat ttgaaggtgg gaaggggatc actaatcaat accgacctaa
    32221 caagttcgaa acatttaaag aattctattc attagcaaat actgtaacag acgatattaa
    32281 taaagacggt atggcggcgc ttcttttaaa agggacaact tcagttattt tttctattta
    32341 tagtacctct gcaagaactt caaaagagaa gaaagacgaa gcaaagcaga tattgagtga
    32401 tccagtgatc cgagaagcca agcaaattgc taagacggat tcttcagcaa aaaaaataac
    32461 aaagttgctt tacaatatgc cagctccact atttttatct gctgtaaaag ttggaagctt
    32521 cgttgaagtg aaaatgccag ggttaatggc tgctttgaag cgagtatatt agttaatgga
    32581 ggaaaatata atgaaaagaa ttttgcattt tcagggacga atgggtttag gtggagcaga
    32641 gtctttcatg atgaatttat atcgtaaaat tgatcgtaca aactatcaat ttgatttttt
    32701 gatttatgaa gattatgcag atgttcaaga ctatcattca gagattgaaa gattaggagg
    32761 ccgtattttt gttgtaccta atcctaagaa aaatattttt aaatatttaa tagaagtgaa
    32821 taagttacta aaaaaagaat ctttttctat agttcacaat caggtttatt ttggcggggg
    32881 aattaattta tggttagcca aaaagaatgg aatcagacag agaattgctc atagccatgc
    32941 aactgaagat ggaaaatctc aaaatattgt aatgaatgta ttgcgtaaat ttttaaccaa
    33001 attgttgtta caaaatgcaa cagactacct tgccgttagt caagaagctg gtgaaagtct
    33061 gtttcaaaac cacccctttg agatagttca taatggtatt gatttagagc tttatagtaa
    33121 aaattcagaa gctaaggtta ataagagaaa agaattggat atctcaatga gtacttttgt
    33181 tgtgggaaac attggacgat tagagaaaca aaaaaatcaa tcttatttgt tagagatttt
    33241 tttagaaata ctaaaaatga attctgattc ttacttgatt ttagtaggtg aagggtcact
    33301 tagaaataaa ctgaaagcca aagcagtaga attggatata gagaaaagag taaaattttt
    33361 aggagaaaga aacgatattc ccgagttatt atctgtgatg gatgtttttg taatgccttc
    33421 tctttatgaa ggtctgccaa tggttggatt agaagcacaa gcagcaaaat taaaattagt
    33481 cttagcagat actatttcca aagatacaaa gttaacaaat aatgtggatt ttgtatcatt
    33541 agatgaaaca ccacaagaat gggcaaaaaa agtaataaaa gagccgtatg ctaataaaat
    33601 aacacaagaa ctaaagagtt atgatgtttc gtacactact gaacaaatgg agagtatata
    33661 tagtagagat cattaaaaat gttcaagata ttttaggagt gattattttt gaaaatatgt
    33721 tatttgatat tggcatacaa tgatattggc aacttaaaga gattggtcaa tcgattgaac
    33781 gaaaatgcag tttttattat tcatatagat aaaaaaactg atatagaacc atttattgaa
    33841 gcatttaaat catatgataa tgttgaattt ttatgtaata aaaaccgtgt taaaatttat
    33901 tggggtggtt tttccattgt acaagcagaa atcaatttag taaagagagc attacaa
//
LOCUS       DACCVZ010000025        31430 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.025, whole genome shotgun sequence.
ACCESSION   DACCVZ010000025 DACCVZ010000000
VERSION     DACCVZ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.025"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            322..1191
                     /locus_tag="IVW63_001193"
     CDS             322..1191
                     /locus_tag="IVW63_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HAP7859478.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1400..2425
                     /locus_tag="IVW63_001194"
     CDS             1400..2425
                     /locus_tag="IVW63_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAP7859479.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2464..3414
                     /gene="manA"
                     /locus_tag="IVW63_001195"
     CDS             2464..3414
                     /gene="manA"
                     /locus_tag="IVW63_001195"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAP7859480.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3508..5211
                     /locus_tag="IVW63_001196"
     CDS             3508..5211
                     /locus_tag="IVW63_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7859481.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5213..7246
                     /locus_tag="IVW63_001197"
     CDS             5213..7246
                     /locus_tag="IVW63_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP7859482.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7257..7697
                     /locus_tag="IVW63_001198"
     CDS             7257..7697
                     /locus_tag="IVW63_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP7859483.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7897..9024)
                     /locus_tag="IVW63_001199"
     CDS             complement(7897..9024)
                     /locus_tag="IVW63_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7859484.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(9027..9704)
                     /locus_tag="IVW63_001200"
     CDS             complement(9027..9704)
                     /locus_tag="IVW63_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7859485.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9968..11734
                     /locus_tag="IVW63_001201"
     CDS             9968..11734
                     /locus_tag="IVW63_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAP7859486.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11749..12186
                     /locus_tag="IVW63_001202"
     CDS             11749..12186
                     /locus_tag="IVW63_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP7859487.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12199..13350
                     /locus_tag="IVW63_001203"
     CDS             12199..13350
                     /locus_tag="IVW63_001203"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAP7859488.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13412..14110)
                     /locus_tag="IVW63_001204"
     CDS             complement(13412..14110)
                     /locus_tag="IVW63_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobyric acid synthase"
                     /protein_id="HAP7859489.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(14103..15455)
                     /locus_tag="IVW63_001205"
     CDS             complement(14103..15455)
                     /locus_tag="IVW63_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HAP7859490.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15678..17078)
                     /locus_tag="IVW63_001206"
     CDS             complement(15678..17078)
                     /locus_tag="IVW63_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HAP7859491.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17239..17976
                     /locus_tag="IVW63_001207"
     CDS             17239..17976
                     /locus_tag="IVW63_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HAP7859492.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            18101..18580
                     /locus_tag="IVW63_001208"
     CDS             18101..18580
                     /locus_tag="IVW63_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HAP7859493.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18577..19344
                     /locus_tag="IVW63_001209"
     CDS             18577..19344
                     /locus_tag="IVW63_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859494.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19574..20143
                     /gene="lepB"
                     /locus_tag="IVW63_001210"
     CDS             19574..20143
                     /gene="lepB"
                     /locus_tag="IVW63_001210"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP7859495.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20247..20849)
                     /locus_tag="IVW63_001211"
     CDS             complement(20247..20849)
                     /locus_tag="IVW63_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP7859496.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20955..21424
                     /locus_tag="IVW63_001212"
                     /pseudo
     CDS             20955..21424
                     /locus_tag="IVW63_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21530..22114
                     /locus_tag="IVW63_001213"
     CDS             21530..22114
                     /locus_tag="IVW63_001213"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAP7859497.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            22117..23190
                     /gene="prfA"
                     /locus_tag="IVW63_001214"
     CDS             22117..23190
                     /gene="prfA"
                     /locus_tag="IVW63_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAP7859498.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23183..24022
                     /gene="prmC"
                     /locus_tag="IVW63_001215"
     CDS             23183..24022
                     /gene="prmC"
                     /locus_tag="IVW63_001215"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAP7859499.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            24015..24194
                     /locus_tag="IVW63_001216"
     CDS             24015..24194
                     /locus_tag="IVW63_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859500.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24216..25241
                     /locus_tag="IVW63_001217"
     CDS             24216..25241
                     /locus_tag="IVW63_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAP7859501.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25432..26676
                     /locus_tag="IVW63_001218"
     CDS             25432..26676
                     /locus_tag="IVW63_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAP7859502.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLHGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26829..27776
                     /locus_tag="IVW63_001219"
     CDS             26829..27776
                     /locus_tag="IVW63_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP7859503.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27910..28539
                     /gene="upp"
                     /locus_tag="IVW63_001220"
     CDS             27910..28539
                     /gene="upp"
                     /locus_tag="IVW63_001220"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAP7859504.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28678..28920)
                     /locus_tag="IVW63_001221"
     CDS             complement(28678..28920)
                     /locus_tag="IVW63_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859505.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            29041..29113
                     /locus_tag="IVW63_001222"
     tRNA            29041..29113
                     /locus_tag="IVW63_001222"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29074..29076,aa:Thr,seq:cgt)
     gene            complement(29232..29870)
                     /locus_tag="IVW63_001223"
     CDS             complement(29232..29870)
                     /locus_tag="IVW63_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP7859506.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29993..30625)
                     /locus_tag="IVW63_001224"
     CDS             complement(29993..30625)
                     /locus_tag="IVW63_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAP7859507.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            30976..31275
                     /locus_tag="IVW63_001225"
     CDS             30976..31275
                     /locus_tag="IVW63_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP7859508.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT        10723 a         5492 c         6316 g         8899 t
ORIGIN      
        1 cacaaaattt ttcttactac tcgaaactaa gcgacttttt cacaacctct tccttaaacg
       61 gtgttcaaaa gcttgcatct gcggtaataa gcccaaccaa acgaaaaata ggaggagcta
      121 tttttgtttg gctgttctta ttacttgatg cagaacagct ttttcacaac ctctttttat
      181 aagagttttt actcattaat ttacaaaaaa caagcaaaat gcgaattttc tcacattttt
      241 tttaacaaaa tcaaagttat tgcttgaaag aagaagaatc catcgttaaa ataaagcttg
      301 acgtagaggg gagcaagaaa tatgaaagat tttcaattgg gggctgccac ctatttaaaa
      361 agtgtagcca ttcgggtgaa agaccgagat aaaatgattg atttttacaa gaacgttgtt
      421 ggctttgatt tgaaaagaga agaaaacgaa ttagccattt taggaacaga agaagctgga
      481 agtgaaatgt tgctgctgga agaaagtcct agagcgaatg atcacatggg ggtgatcaaa
      541 aagctgaacc gtttttcatt gattatccct agcacagaag aaatggcaga tatcctttgt
      601 cgtatccgta aaatgaatta tccaatcaaa gaagctttag aagatcatgg acgtatgggg
      661 attttgctcg tagacccaga agagaatgaa ttggaaattt accatgaaga gaataagaac
      721 gaccaaagag aaattccaga aacaatggat caagaagcat tattaagaaa atctgaagaa
      781 aaattcagta aactatcaac aggttcttat tttgaaaaaa tccatttaaa tgttactaac
      841 ttaacaaaag aacgccaatt tcttaatcat gtacttggtt tgaaggtaca taatgaagaa
      901 gagggcatcc atgtattgaa tgaaggagat ttccatgttg gtttgacaga agctagcgga
      961 ggcgcaattg atttgcctac agatgaagtg attggacttg attttctgaa attcatgatc
     1021 gatactgaaa gcatggaagg actgattgct cacttgcagc aactatcagt tgatttcttc
     1081 ttagacaaaa agcacacagt actcacaatc tatgatgcta taggaatcga atggtggttc
     1141 gtcagtgagc caaaagaaaa gaataaaact gacattcgat gcgacgctta actttttctt
     1201 tcttaacgat tgtcgcatgt ctcgtcattt tatgaacggt catactatcg cttattctag
     1261 agatagaaag agaaaatagt ataccggggg aaactgcgcg gtttttcgcg cagttttttt
     1321 gtgtaaaaaa ggttgattcc tcatagatta agctttaagc ttggactgta agaatctgat
     1381 agaaaagcag gagaaaaaga tgtatccaca cacgaaacag cttattttga aaaagatgga
     1441 agaaggattt tatccaggtg tagcagtcgc cttcataaaa gaaaatcaag tagaaacatt
     1501 tacagccggc tttgcccaag tcgttcctga aaagcagctg atgacagaag atctgttgtt
     1561 tgatgcagcc tcactgacga aagtcgttgc aaccacttca ttagttttac gtctattaga
     1621 agatggaaag atagaactcg atcaaccgct tcataaatat cttcctgaat ttgaaaatca
     1681 gacaatcact ttgcgtcatt tactgacaca tacttctgat atcaaaacat ggataccaaa
     1741 cagagataag ctatctcagg aagaattgat cgccgcttat ttgaagctag aaccaggtga
     1801 gcaactagga aaagaagtaa aatatacaga tgccggtacg attcttcttg ggttgatgct
     1861 agaggaaatt taccaagaaa ctgcagtgga aatctttcaa gaacaagtat tggaaccatt
     1921 aggaatgatg aacagcttat ttcttccttt tccttccaaa aaaatcgttc ccacagaaca
     1981 actgccttcg ggtgaggttt tgcgtggaca aactcatgat ccgaaagcaa gagttttggc
     2041 tgaacatgca ggtaacgcgg gtctctttat tgatttgaaa gacagcatta cttttgtcca
     2101 aatgtatttg aacaagggaa aaatccgtaa tggtcgtttt ttagaagaag agacgattga
     2161 ttctttactg caagatcaaa caccgaaaaa aaatggctat cgttctttag gatgggactt
     2221 aaaaaaggat gtagaagacg gtcatgcgat tctttttcat actggttata caggtacgtt
     2281 tttcttgatt gatataaaaa cacaagaagc gttgatattt ttgtcaaatc gcgtacatcc
     2341 tgtcgatcat cgtgcggagt atctcatatg tcgagatgaa attgttgaaa actttttgaa
     2401 agagaaagcg gtattaccga aataatgcta taatagctat gaaaaatgag aggagtttga
     2461 attatgcagg aacctatgtt tttaaaacca gtttttcaag aaaaaatttg gggaggaagt
     2521 cgtttacgtt cagtctttgg ttttgatatc cctaacgata aaatcggaga agattgggcg
     2581 atcagtgcgc atcctcatgg tgtcagtgta gtagaaaatg gcgaattcaa agggaaaaga
     2641 ttagatgaac tatggtcaga acacaaggaa ttgtttggcc atccttcaga accagtgttt
     2701 ccattattga tcaagatctt agacgcagaa gatgatctat ctgtacaagt acatccagat
     2761 gatgcctatg ggatgaaaca tgaaggtgaa ttaggaaaaa ctgaatgctg gtatatcatc
     2821 gatgctgaac ctggtgcaga aatcatctat ggtcatcatg caaagacaag agaagaacta
     2881 gctgagatga tcaaagatgg gcgctgggat gaccttttga agaaagtacc agttaaaaaa
     2941 ggtgatttct tttatgtacc aagcggaacg atccatgcta ttggtaaagg aatcatgatt
     3001 ttagaaacac agcaaagttc tgacacgact taccgcgtgt atgactacga cagaaaagat
     3061 gcgcaaggac aaacaagaga gctgcatatc caacaatcga tcgatgtaac aactgtccct
     3121 gcgaaaacac cagaattaca aatcaaagaa gtccgaaaag ggaattcatc gatcgtcact
     3181 tatttagaaa ctgagttttt caatgtatat gagtgggata ttaaaggaat cacatctttc
     3241 aaaaaacaag ccccttatac attgatgacg gtaatcgaag gagcaggaga ccttgtcgtt
     3301 gacggaaaaa catatccatt agaaaaagga acaagctgta ttattccaaa tggcgtttct
     3361 gagtgggcgg tccaaggtga actagcaatc attgcgtctg aaccaggcaa atagttccca
     3421 gatagctgaa agcagcagac ggtttttcgt ttgctgcttt ttctacataa aatccgtcca
     3481 tcaataaata gaagtctggt gaaaaagatg gaatacaaat ggaaagcaaa caacagcagt
     3541 cgcgtgtcta tgaaacaact gagaaaagct ggacatcact taaatgaaat gatcatgcca
     3601 aatctaagtc tgtttatcgc ttggggaatc ttgtcattag caacaaaagg tgtgtctggc
     3661 gatttgcaca ccacattaga agaggtatgc cattggatga tccagctgct tttacccatc
     3721 ttgatcagtt attcaggcgg gaaatcggta gggggacaaa aaggggcagt cgccggtgca
     3781 attgcttctt tagggttgat cgctcgttcc aatgctccac aaatcgtagg agcgatgatt
     3841 atcgggccgc ttgccggcat cgtatatgaa caatttgttt ctagattcca tgtgaaattc
     3901 aaggctggat atgaaatgct tgtcagcaac ctactagtag gactgactgg tagcgttatt
     3961 tgtataattg gaatcgtttt tattgaacca gttttaaata gtgttcactt gttgctcgcc
     4021 tccgttgtgt cttggctagt cacaatgaat ctgttaccac ttgtcagtct gatcttagaa
     4081 cctctaaaag tactattttt caataatgca atcaatcatg gtgtattgac acctttagga
     4141 atcgaattct cacaaacagt cgggtactct tccttatttt tgatggaggc aaatcctgga
     4201 cctggtttag ggatcttact ttctatcctt tgttttgcag aaaaacagga aaaagtaaat
     4261 gcgagtggag cattgatgat ccatgcgatt ggcgggattc acgaaatcta ttttccattt
     4321 gtcttgctgc gaccgtatct atttttagct gtaatggctg gtggggcaag cggcacgttg
     4381 atatttcaat ggttagatac gggattagct gcacctgtat cgcctgggtc actactcgtg
     4441 atttttgcca atgcgcctta tccacaacta gctggggtaa gtatagggat agcaatcagt
     4501 acatttgtga ccttcatttg tgcagcgata ctattgaaat taccaaataa agaaaaagag
     4561 aacaaaacgg tcaaagaaag gggagaaatc ttggaaccat ctatcattca ttccgtcatt
     4621 tttgcttgcg actcaggtat gggatcaagt gctatgggag ccgccctgct gaaaaagaaa
     4681 ttagcagcag aaaaaatcga tctttctgtc ggatacagct ctatctatga attgaataac
     4741 caagtaaatc agctggttat cgtgcaacat gaactagcgg gtcttgcaag agaaaaagta
     4801 cctcaaagtc aaatctatgt actggatcac tttttggaaa cagatatctt gctgtcacga
     4861 ataaaagaag cgatccaatt tccaaagcgg gaagaaaaaa aagagatagc agatatcaca
     4921 gaacaaaaaa cgtcgcctgc taatattgta tttttgtata aaaacaacag acgcggctca
     4981 caaactatgg gcatgacgat tttaagtcaa ttagcaaaaa aagcgaaaaa acagtttgtt
     5041 atctcaaaag aatcaataga aaaaatcaaa atccaagaag aaacgattta tatcgcacaa
     5101 agagaactag ctgtaactga acagctagaa gaaaagatcc ctcggctagt tctagttgaa
     5161 cattgggtag ctacgaatga atacgaaaaa ctcgtgaagg gagaaatata agatgtattt
     5221 atcgcccaga gaaaaacaat tattagcaga atttctcagt agcccgtcac ctgtatctat
     5281 ccaaaaaatg atgaatttat tgaaggtcag taaacggact atttaccgcg aattagataa
     5341 tcttgaagtc tcattgaaat cggtaaatgc ttctttgaaa aaagcagcta gaggctcatt
     5401 tgtcattgag gcatcagaag aagtattaga gcaattaaaa gaaaatacag atgggaaaag
     5461 taatgactta tccactgcta aacgacaaca cgcgatttta gccgagttgt tactgacgac
     5521 agagccgttg agtcttgctc atttcatgga atcatatcgc atcagtaata ccacttttta
     5581 tgcagatatc aaacagttgg aagaaagtat tcgccaactg cctttggaaa tcattcggaa
     5641 ccagggatac gagatcgaag gaccggaaaa ataccgccgg cttctgacag cgaatgtatt
     5701 agaattagaa atcaatgaat atgaactttt tcatagtatt tctttcgatg catcactgaa
     5761 ttattttttt cgattcgttg atccgcaaca tctatctctt gcacgcaaag taatcgggga
     5821 agaattgatc caaaaaaaga ccaatctaag tgatagaaag cttgaacatt tggttttgat
     5881 gctgacattg acgatggagc gtgtgacgaa aaatcattta ctgacaaatg agacatataa
     5941 tagtctggca aacaaagaat tactacagac agctaaacga ttgttttcac ggatcgcttc
     6001 tgagacaaaa caactttatc cagtaaatga gatcgtcttt tttgcaggat tattaaatga
     6061 cttcacgaac tcatttgatc agaatttctt tgaagagacg ttcgatacac agcttgctta
     6121 tttagtaaaa caactgattc aagaagtaag tgaagagacg aatgtccatt tttatgaaga
     6181 tgaaactttg tacaaaatgc tgttgactca tttatctggt gtgttttcaa gagccgtttt
     6241 acaagaagag acactgacca atccgatttt agaaaaaatc atggttcaat acgaggaagt
     6301 tgcgaatgca atccgtaaag cagtagagcg gatttttcaa gaaaaaaaat tatccgaaga
     6361 agagatcgct tatatggtcc ttcattttgc gaattcattg gaacgaagtc cgaaagaaag
     6421 caatatcagt attgcaggat tttcgccaag tggattagct tctactagca tgttggaact
     6481 acgattgaaa aggtattttc ccttcatcca acaaattcat ttctatcgga ttgctgattt
     6541 aaaaaaaatc gatttacaag aagaatatga tgttgttatt tctacatcta ttttaccagg
     6601 atacggtgga aaatatattt tagtctcccc gctactgcta gaagatgaag tcaagcagct
     6661 aaaagaagct ttttcgcata ttgagaagaa aaaaaggcaa aaaattacgt ataacagcaa
     6721 taacgagtgg atgatagaag atacttatga ggaaacaatg catttcatgg atcaaatcaa
     6781 tcaattactc ggtcgttttt ttatccaaga actggataat cctgagacga tttccgaaac
     6841 gattcgcagc ttatttcctt attttcctga aggactagta acggatgaag aggtggttca
     6901 tcgccggctg cttaagcgat atgaacaagc acctatcggt attcctcata caaatatggg
     6961 gttattccat acatccagct cattgatttc taaaccgatc ttttgtattt tcaatttgaa
     7021 acatccgttg accattgaag ggatggatag acagccagtc gatttgtccc gtatgttagt
     7081 tatgctggcg ccttcgccaa tccaagaaaa agacgggatt cttttaggaa agatcagtgg
     7141 agcaatcatc atgaatgact tgaacaccga gatcttccgc tcaggaaata aagaaatcgt
     7201 ttatcagttg ttagcgaaaa tcctgattga agaaataaag aaatgaaggt gaaaagatga
     7261 tacagctacc agcagaaaaa atattgctcg atcaatccta tcaaaattgg aaagaagcgt
     7321 tgaccgagat cggccagtgg atgacccaac aagggggaat caaaccggca tatatccaat
     7381 caatgatcga aagacaagaa aaagcgagtg tctatatcgg gaatttcgta gccttgccac
     7441 atgggactga caaagatgaa gaagtagtag aagaaggaat ctatttagtc caagtgcctg
     7501 atggtgtgga ctttggaaca aaagaggaac caaaaatcgc gacactctta tttgtagtgg
     7561 ctttaaaaaa agaacatcag ttagcggtgc tccaagattt agcctttttc tgttcagaca
     7621 tcgaccaagt aatggcgctc agtgatgcgg aaaccattga agaagtccaa atgatttttg
     7681 aacatggaca tatataacca atgttcacag taaaaaaagc tgccttgcat caagtaataa
     7741 cttcaaccaa gataaaaata agaggagcta tttttgttgg gaggttctta ttactgcgga
     7801 tgcaagcttt tgaaaactat ttattctaga aaaccgttta tttgaaatag gggacggtga
     7861 caaggttttt gtcaccgccc ctattatttt tgtgttttaa tagctctttt ttatatagat
     7921 agtgcccata cctatgaata ataaaacgat actccatata ccaagtgtca agataccatt
     7981 catgaaagta acctgttctg aagctagtgg cgagaaaata tctcctccta tgatcacatt
     8041 ttgaaaatca acataagaag ttggcaagta atgactgatt gattctatcc atccaatcga
     8101 agaaaacaag cgatactctg ctaagaaaag acaaagaagt gtacctaaaa gattgactag
     8161 agaatgttca aataaagcag atagaagaaa actgattgta cttaaaaaga gcacccacaa
     8221 caacaggaac agaaagctct ggaaaagata ctcatacatc ggcaggattc gtatctcctg
     8281 accaatgatc gttcctacag gataacggaa gtctcccaaa ccatttttga ttattactag
     8341 tatagagacg atcaaaaatg gcatcacgag acttagcata gctgcaccat aataaatggt
     8401 aaaacggatg ctatgtttct ttaccatact atccagtaat agattgacta gagagattac
     8461 ctgctttctt ttttcataag agatgatgga agaaagaaac aaggcggtta tacataaaat
     8521 caaaaaacta gaaatcattc ctgaaaaaat attttcgtag taatttgcta aagagagatg
     8581 cgctggcaag tcaaaaatag aatatctttg gatctgatgt tctttcatat aacggagcaa
     8641 ctcgacacgt ttttgttgtt caatgattgg aattccttgt ctttgaccag aaatcagtcg
     8701 atccagtata tctttttcat aatgataagt tgcttcgacc atttgctgga cattccctgt
     8761 gttttttgca tgtaagattg cttcgatcag tttgttgctt ttctctaaac tttccacaaa
     8821 ttctttctca ttctcatctt ctttcaacgt ttcaatcaaa cgttgcatct cttcatagtt
     8881 atgattcagt tcatcgaatt ctgtataagc aagtttatga tcaaaaaaaa gtgggaatgc
     8941 aaagagcacg accaacaata gaggaaataa aaagtttact ttgtttttta gtaagagatt
     9001 gcgttcaaat gtaagtaaag acatagttac acctcatata atttacgata aatagctaaa
     9061 atctcttcca tatttgagga ttctgtgacg atttctccat tttttagaaa acatgcttta
     9121 gaacaaatcg attggatatt cgcgatagcg tgggaagaaa gaagaatcgt cttcccctct
     9181 ttctgccatt gtctgatgag gctattcaag atatcaatac ttcctgggtc taatccgttc
     9241 aacggttcat cgaataacat gacagatgaa tcactgatca agtaagcagc aagcaagaca
     9301 tgttgtttca ttcctagaga catttttcca atcggcaaag taaggtactc agtcatcttc
     9361 aatcgttgga aaacagtttg gcattctact ttgctctgcc aatagtattt gatcaaagtc
     9421 aaataatcaa cagccgatag atagtcggat aactgattcg ttgattctag aaaaaagaaa
     9481 gaccggcgat aatctgtata agcagtagga gagatgttgt gaagggacaa ttgatcataa
     9541 gttgttggca gcagttgggc aatgccattc agcaaagttg ttttgccaaa tccgttcggg
     9601 gcaatcaaag cagctacttc tcctgattct actaaaagat tcaattgtcg aatcacacgt
     9661 tttttaccac gtttcatgtt catgtttttg atcagtaatg tcatagatag gcctccaata
     9721 taaaatttaa taacataata gaatggaaaa catctaaatt aaatgctaac aaaagttatt
     9781 gtttgcatat tataaaaaaa ttaaaataac agttttattt aaaattgaag ttttctgata
     9841 ccgaaatctt tttattttgc tgacatactc aaacctttgg cacaaagttt cgtgccaaag
     9901 tacgactatt tctcttttta gtaagcggat acaattagag tatcaaaagg agagagggag
     9961 agacaaaatg gaacggacga ttcccaaaaa caacatttcg ctaaaagcga gggtacaaaa
    10021 attaggcagt actttatcaa gcatggtcat gccaaatatt ggagcactga ttgcctgggg
    10081 tgtattaacg gctctattta tcccagatgg ttatttacca aatgaggctt tcgctaccat
    10141 ggtaagccca atgctaactt atctgattcc tttattgatc ggttatactg gcggaaaagt
    10201 aattgctggt gaccgcggat cagttgttgg ggcaattgca acgatgggtg tgattgtcgg
    10261 aacagatatt ccaatgatgc taggcgcgat gatcatggga cctcttggtg gatatgccat
    10321 caagaaattt gatcagctat tccaaaaacg gatcaaatcc ggttttgaaa tgctagtcaa
    10381 taatttttca gcaggtctta tcggttttgg attagcgtta ttaggttttt ctgcgattgg
    10441 tccagttgtc gatgcattga ctcaagcaat ggcaaaaggt gtagagatca ttttatctgc
    10501 ccatttgatt ccattgacaa gtatttttat tgaaccagca aaaatcttat ttttgaataa
    10561 tgcaatcaat catgggattt tgacaccatt gggaactgaa caagtagcag aggctggaaa
    10621 atctattcta ttcttgcttg aagcaaatcc tggtccagga cttggcgtat tacttgcttt
    10681 tactttgttt ggcaaaggag cagcaaaatc ttcagcacca ggagccatga tcattcactt
    10741 tttaggcggg atccatgaaa tctattttcc ttacgttatg atgaaaccgt tattattctt
    10801 atcagttata ggcggaggaa tgtcaggaag tttcattttc caattgatgg atgctggact
    10861 aagagcgcca gcttctccag ggtcgatcat tgcgattcta gcgatgacac cgttcaattc
    10921 ttaccttcct gttattttgg gcgtgattgt tgccgcagct gtttcgtttg gtatttctgc
    10981 agtaattttg aaagcggatg cgaaagatac aaatgaagac ttcgaaaaat ctgttcaaga
    11041 gacaaaggca gctaagcaag cttccaaagg tgcccaaggt attcctcaag gagctacatt
    11101 ctctggcgta caaaaaatca tttttgcttg tgatgcagga atgggatcaa gtgcgatggg
    11161 cgcttcgatc ttgagaaaaa aagtacagga agcagacttg cctcaaacgg tgaccaatca
    11221 agcaatcagc caactgacag atgactcgaa tacattgatc gttactcagg tcgaactaca
    11281 agaaagagca aaacaaaaag caccgagcgc gcgttttgtc tcagtagaaa actttttgaa
    11341 ttcacctcga tatgatgaaa tcattcaaga attaagcagc aagcagaaaa catcagtttc
    11401 tgaaattgag aatgagccag cagaagagtt tctttcagca aacatcaaac aaatcaaaga
    11461 gattctactt gtccacgatg atcgttccgg atcagcaaca atggggatga ccgtgctcaa
    11521 agatatatta gacaagaacc atttaactat cccgttaaga aaagtcaata tccaagattt
    11581 aaaagatgaa cctgattcac tgatcgtagc caaagaaagt ttagcggaaa aagtacagat
    11641 ggctgcacct caatccattc atttatcagt caacagcatg gtcaatccgc aaaaatacga
    11701 atcgattgca caatatttga aacagacagc ttaagggagg aaaacagcat gcaaagtttg
    11761 ccattcgaca tgatcgagct caatcgatct tttaaaacca aagaagaagc gatccgctat
    11821 tgcggtcaga tgcttgtaga agcagggtgc gttgatgagg aatatatcga tgccatggta
    11881 gatagagaca aaatgttatc tgtttatatg gggaatttta tcgcgattcc tcatggaaca
    11941 gatgaagcaa aaaaatatgt gaaaaaatcc ggcatctgtg tcgttcaagt accagatggt
    12001 gtagattttg gtaccgaaga agaagaaaag attgcgactg ttttgttcgg tattgcagga
    12061 gtcggagatg agcatttgca acttgtacag caaatcgcac tttattgcag tgatatggac
    12121 aatgttgtcc agctagcaga cgcgctcagc aaagaagaag taacggaaaa tctagcaatt
    12181 gcttaaggag agagaaaaat gagagcagta cattttggtg caggaaatat cggtcgagga
    12241 tttattggag aggttttggc agctaatgga tttgagatta ctttcgtaga tgtgaatcac
    12301 acgatcattg atgctttaaa tgaaagaaaa gaatacgaaa tcgaattagc agatgaatca
    12361 aaagaaaaaa tcactgtaaa aaatgtcaaa ggaatcaaca atcaaacaaa tccagaaaaa
    12421 gtaatccaag aaatcgctga agcagattta gttactaccg ccattggccc gaatatctta
    12481 ccttttattg ctgagttgat tgcaaaaggt atccaagaaa gagaaaagga aggaagcaca
    12541 acatctttag atatcattgc ctgtgaaaat atgattggcg gttcagcatt tctagaaaaa
    12601 gaagtgtata aatatcttcc ggaaacatca tttactgaca aatatatcgg ctttccaaat
    12661 gcagcagtcg atcgaatcgt cccattacaa caccatgaag atcctttatt cgtccaagtg
    12721 gaacctttca aagaatgggt cattgacgat agccaaagaa aaaataaaaa aatccaatta
    12781 aaaggggttt tatatgtaga tgatctagaa ccatatatcg aacgcaaact atttagtgtc
    12841 aatactggtc atgcgactgt cgcttataca ggtgccttgt taggttacca gaccattgat
    12901 gaagcaatgc aagatgcgtt agttgtggca caattaaaat cagttttgca ggaaacagga
    12961 agtttgctga ttgccaaatg ggggtttgat gcagagcagc atcatgcgta tattgaaaaa
    13021 atcattcatc gcttccaaaa caaaaatatc tctgatgcga tcacacgtgt cgctcggaca
    13081 ccattacgta agttaggtta tcaagaaaga tttacacgtc cagtgagaga actacaagaa
    13141 cataacttga cttgcccaca tttgacggca acaatgggga ttatttttaa ttactatgat
    13201 cctgaagatg aacaaagccg tcaattgcat gaaatgaaga tccatgaaaa cttggaacaa
    13261 ttgattcaag aagtcacagg aatcaatgat ccgaaaacaa tcgggaatat caagcaaaac
    13321 gtgaaccgtt atgccaagca agtcgcttaa aataggatac gaaaaagggg aatgtgacga
    13381 aatttttgtc acattcccct ttttcgaata actaggctgt ttgtccttca agatagggca
    13441 gatccaattc tttaccgtaa cgttgttcta aagctaggcg gatcaaacga gctgccaggt
    13501 tctcatttct tgcaaggata ggtccatgga aataagaacc gaagacattt cggtaaatga
    13561 caccttcaga ttggtcttca ccattatttc cttgaccttg taccactttc cccaaaggtc
    13621 gttcaccttc acctaagaaa gtccgaccat tgtggttttc aaatccataa taagtttcat
    13681 tgaattcttc gttatggata acgatatcac cgataaaccg gttattttcc tgacttaacg
    13741 tgtagtgatc cagtgcactg attccttgga tcttttctcc attagctccc atgtagtagt
    13801 gacctagcaa ttggtagcca ccacaaatgg ctaacatgac gccatcattt tcgatatagt
    13861 tgatcaaaga atctttcttt ttctggatgt cttttgaaat gattaattgc tcaaagtctt
    13921 gaccaccgcc aaagaaaacc aagtcatatt tatcagcatc aaaaggttca tgtatactaa
    13981 cgatctccgt atggcaagaa acccccattt tttctgctat atatttcaac atcaaaaggt
    14041 ttccgttatc accatatgtg ttcatcaaat ttccataaag gtgggcgata ttgagttcat
    14101 aattagccac ggttcattcc tcctttgata aatccttgag cagctagttc tttacgaagc
    14161 tgcaatacag cagtgtaagt agctaaaata tagacatgct cagttggcaa ttctttgatt
    14221 ttttcgatta cttctggtaa ttcttttgtt tctgtcaatt tattttctgg aatcccggca
    14281 acttttagac gtaaagtcat atctgtatga cggtctcctc cagaaataac agctgggata
    14341 tccatatcgg caaagttttc aaaattacca tcccaaatcc agctgacatc gattccgtct
    14401 gcgtaattgg catttaataa agccactaaa gaaaatggat aaggagctag accaatcata
    14461 tcgattactt gattgatacc tacaggattt ttgacaagta ctaatgtaca ttttttccca
    14521 ttgatattga tgacttcttg tcggccgaat actttctcgt catatcctaa accttgtttg
    14581 attttatcag gatcgacatt gaagtactct gccactgcag tagctgctaa agcattgtag
    14641 acattataca taccgccaac ttcgattccg tattcatgac catcgatcac gaaatctgct
    14701 gacacattgt ccatccgtac catatcagtt aatcgataat ccaattcagg acgtttgaag
    14761 tcacaatttg gacagtaata tttccctaag tttgcataag tgatcatttt ataatgcaag
    14821 atgtgatgac aatttggaca taagacaccg tctgtattgt aatgagccat ttgttcacga
    14881 tcttcttcat ggtcaaagcc ataatatttt ctaggattga ctgtttcgat agaattgaag
    14941 attggtgaat caccgttact gataatcgtt gcatttggtg actttgcggc accgtctaca
    15001 atcattttat aggtcgtata gatttctcca taccgatcca tttgatcacg gaaaatattt
    15061 gtaaataaga acagttctgg tttcatatat tctgtgactt tgctcaaact tgcttcatct
    15121 atttctagga cagcaaactt tttctgtcct ttttttggtt ttgcctgcaa gaaagtcgat
    15181 acaattccct gtaccatatt cgcaccagta gggttggtta gaacttcatc gaattgctgg
    15241 cgcaaaatat tgactgttaa agcggtagtc aatgttttac cgtttgttcc ggtgacaacg
    15301 acgacttggt agtcttttgc caaactatct agtatatgtg gatcgacttt cagcgctagt
    15361 ttacctggta aacttgatcc gcctttaaaa aaagttttta atgcccattg cgacgttttt
    15421 ccaactgcaa tcgcaaaatg actgcgtatt cccattatgt aacctccaaa aacgatttgc
    15481 tgacgaataa attcaactaa tcataccata tgttgaaaaa aaggttaaat tgcttttctt
    15541 attcttaaga aaaggttacg gctgaaagtg catgaaatcg gacaaaatcg catgatttaa
    15601 caaaaaaaca gcttgaaaca aaatgattgt ttcaagctgc tgtgatttta ttattccctc
    15661 ttacctatat tcccatttta accgataata attttctcgc ttggatattc atagcctaga
    15721 tctcgtgttt cttttggcac gaataacatc aatgtatata gcattccgat ccgcccaata
    15781 aacatcagtg tagcaatcgt gattttgccc acaacagaca agtctccggt aatccctaaa
    15841 gataaaccag ttgttccaaa cgcagaagtt acttcgatga tgatcgagat cagcgtttgt
    15901 tcttctgtag cagataaaaa aacgatacaa aagaaacaca taccaagaga aagcataaag
    15961 acaacgactg attttcgcac atcatcttga tcgattctcc gtccaaaaat attgatgtta
    16021 tcttcacttt tgaggaagga atatagatac aaaccgatga ttgctacagt agttgttcga
    16081 atcccgccgc ctacagaact aggactgcat ccgataaaca tcagtaaaga aaaaatgatc
    16141 agtgttgtga tttgaaaatc acccaaatcg tgaatctgca gaccagcatt acgagtcgta
    16201 atcgaataaa acatcgaatt gatccatttg acactcatat tggaatcttg gaataaatgg
    16261 tccttttcca atagataaat caagacagtt cccgaaacaa acaagataac aaaagctaac
    16321 acagctaatt tggtaaacaa ggaaaaacga aacggaagct tcgcattgga acgtttgtat
    16381 aatagccatt cccggcactc catcaataca ggaaaaccaa ttcctccgac aaaaatcaaa
    16441 aacatgatca ggatcaagaa aaaatagtca tgtgcaaagg gcttgatgga atccccagtg
    16501 acgtcaaacc cagagttcgt gacagccgat atcgcctgat aaaaaccgta aaaaacggca
    16561 tcacgccaac gatcaaaata gcctctgtaa taaaaataaa tagaaaagaa tgtcccaaaa
    16621 agtaattgaa accagattaa aatagcaaaa gtgatccgaa tcagtcggac gataccagac
    16681 aaacgcggtt gattcatatc cgtcatgatc agctgtcgct gtttcagtgt gatccgtcgt
    16741 ttagaaaaaa tgacaaaagc agtagaaatc atcatgatcc ccaaaccacc aacttgaaat
    16801 aatatttcca gcagtataat accgttatca ttgaacacag aattgatatc aaaagtcgat
    16861 agtccagtca cactcactgt actgattgcc atgaacagca tgtccacaaa agaaacatgg
    16921 ctatctggtt cgcgaaaaat cggcatataa aatagaacga gtgataagac cgtcatcaat
    16981 atataataaa aaacgatgat ttggatcgat gagaaatgat tggcagcaaa cttctgtcct
    17041 cgccgctgca gccttcgaaa gaataaatca acatgcacag tactatcctc ctgacaatag
    17101 tcgtttctac cagtatacaa ggggaattag gaatactcaa agaaattatc aaacagataa
    17161 caatacagct ttcgattaaa atagaaatgg cttataataa ggaaaatcct agaaaaaaga
    17221 aggaggagga ataacaaatt gattaatgct caacaaatcg tagaaaaaat gaaaaatcaa
    17281 aaaataaatt atgatacagt tctgaaaaaa atgatcatgc aatgggagaa agaagaagta
    17341 aagcctaaga tattaataca tacatgctgt gctccttgca gtacgcacac attggaattc
    17401 atgtctcaat atgcagagat cacgttattt ttttcaaatt cgaatattca tcctaaaagt
    17461 gagtatttgc gaagattaca tgaacaaaaa cgatttgtag accaatttaa tgagaaaact
    17521 gaccatcatg ttgcgctaat cgttgatgaa taccgtccaa atgaattcac caaaatggtt
    17581 ttaacaaacc atcttgaaaa cgaaaaagaa ggtggtgctc gctgcagtgc atgcttcaat
    17641 atgcgattag atcttgttgc gcaaaaagcg caagaactag gatacgatta ctttggaagt
    17701 gccctgacca tctcgccaaa gaaaaatgca gctttgatca atcagatcgg aatggatatc
    17761 caaaagattt acgggacaca atacttgcca agtgatttca agaaaaacaa aggctatgaa
    17821 cgctctttgc aaatgtgcaa agagtatgat atttatcgcc aatgttattg tggttgcgtg
    17881 ttcgctgcca agcagcaagg atgcgatctg aaagaaatca atcgggaagc aaaagcttac
    17941 ttaaaaacat caaccgtagt ttttgaggaa aattaaagaa atctttcgga aaaacgtaag
    18001 aaaaaaataa agaatttatg gtagaaataa ggtagactgt ataatttgtc cgtagtaaag
    18061 taaggaaaca agaataaatt tcaatgaagg aagagataag atgcgaaaag tagcacctat
    18121 tttgaagcca atcgctgtat taacaatctc gacgattgtc gcgactacta caggtattgt
    18181 gaatagttcc agctaccgtg caccaagttc aagttctagt actgtagaag aaacaacacc
    18241 aactacttca gtctcgacat ctgaaccaac aacaacggaa agtttgaatg aaaccactac
    18301 gacaagtaca tgggacgata caacaactag ttcgtcgtat gatgagacat atacaactga
    18361 cagctcaagc gaaacaagta atacggtacc agatggcact ccatcggatt caaccaatcc
    18421 aagtacaagt ccggatacaa gtgctagctc cgaaacgata ccaagcagta cgactgtaga
    18481 tgataacacg caaaatgatg atgcagcacg tacagcacag caaaaccaag attcaggaaa
    18541 tacccaaacg tataaccagc aagcaggtga ttctcaatga catttttact agaccttatc
    18601 aacggggtgc ataaattcct tggctattta gacatcagtc ctaaatatct taaccgtgga
    18661 tatacgattt taagtgtgat tcccacgctt tatttattga gaattgttta tggactttgg
    18721 caaaaccaaa actatcttca atttttctta tatggacttg catttctagt gcttgtttat
    18781 tttactgttt taaatgtatt ttattacttt ttagataaaa acacgaaagc cgatgtcact
    18841 cagctttttg tgaagtattt acctgatgaa gcgttcaaca tccagacaga agaatcgata
    18901 gataatggaa attcgatcga taaagtgaat acacaagagg tcatggtttc ttatgacgaa
    18961 gattatcaat tgaaattagc cgagaatatg cggtatttga ttggaaatgg tgagatcaaa
    19021 acaaatgaac tcggtcgcat ggatggattt ctggtcgata gaaatacatt gtatccttat
    19081 tactatgtca agaaaacagg agagaaagag tatgttctaa atattggacg aagctactcg
    19141 gacatggaaa aagtagggac cattcgactt gactcaacag aagacacatt ggaacctgtc
    19201 ggattgttca tcgtcggcgg tgattttgtc aaagacgggt tacgctatca tgagccttat
    19261 cgtctgaaat tgattgcaaa aaaggcacag tcgcaggaag aaccagtggt ttatagtcgt
    19321 agccaaagaa gaagacattc ataatgtgat gaaacgccgt gtatcagtgg ttgcgataaa
    19381 aacgtttatt cggaataagg gggatgtgac acgtcttttg tcacgttcct tttttatata
    19441 acgagaaaga taagacgaac acatcactta ttctttcctt tcatttataa acattgtaga
    19501 ataaagaaag tacaacgaag tattgtgaaa aaacgtaata aataacgagg aaaatacaag
    19561 taggaggtaa gctgtgaaag aatttttgaa aaattggggg attttgatcc ttgtattagc
    19621 ggctatttta ttagctagag tgtacgtgtt tacaccagtt actgtaaacg ggcattcgat
    19681 ggaccctaca ttaagtgatg gacaacgatt gatttcatct aagatctcaa actatgaacg
    19741 aatggatatt attactacaa aggaaccggg ggatgaagaa cggatgattg ttaaacggat
    19801 catcggtatg cctggagata cagtcaagat ggaaaatgac cagttgacca ttaatggcaa
    19861 aaagtatgat gaaccttatc tggatgagtt caaaaaagaa ttttcagaag ataagttaca
    19921 aggagaatat gcttatagct caggattcca agcacaagca gaaagttcat ccacctttac
    19981 gagtgacttt gaatatactg tgccaaaagg aaagtatctt gttctaggcg ataaccgctt
    20041 gatttcaaaa gacagccgaa tgtttgggtt agtcgacaaa gatatgatcc aaggaaaagt
    20101 tgttttccgt tattggcctc tttcagaaat taaaatcatg tgatgaaaaa ataaaaagaa
    20161 gctgtgacat gttttttgtc acagcttctt tttccgaaaa ttccttctta tttcttggag
    20221 ttgctcactt tttttgcaat ctcattttaa gctttttggc tgatggataa gaaaagcgaa
    20281 gcgtttttgt tcataaatag cttttcccca cgatggaagg tatgactagt agcagagaca
    20341 aagcccgttt tttccaatcg attattcaat tcttcttggc taaagccatt atggactttc
    20401 ggatgactaa tttgttcatt cttgtcaaag tctacgatga tcaattgacc gccaggagct
    20461 aaaatttcat aaagttttgt aagaatattc tccgtatcag gaatgtgtaa aagtacaagt
    20521 gatagaagga tgagattagc ttggacagca ggaaattcga cagaagcatc agcgtggatc
    20581 gttcggacat ttttcagatc tgctgcttgg atcttttctt ctgccatttt cagcatagtt
    20641 tctgaagcat cggcaatgat cagttctttg aatctttccg caagcggtaa actaacaagc
    20701 ccagttccgc ctccgtaatc cagcaggact ttttggtggc tgtcgcgcgg tagataagta
    20761 gttagttctt cgcgaataat cttggctaat gcttgacggt caggggaatc ataatggtta
    20821 gcgatggaat caaaaatatt ttttgtcatc aaatagctcc ttacgtaaaa ctttgaaatt
    20881 ttaacttatt atagcacgtg aaaagaaaga aagcatgcta tactcaattc aaaaagggag
    20941 aatctagaaa gaatatgccg atatcgtttg taaaagatag agaggaaaaa ggaaagtgtg
    21001 tccgagaaat attactagac ttgcctgagt ggtttgggct tcctgaatca acggaaaaat
    21061 atatcgagga atcaagtaaa ctacctttat ggtgtgaaaa aagaaaagaa gaatatttag
    21121 gctttatcac tctttcacag acaagtgaag atactgccga aatctattct attgtatggg
    21181 aataaaaaaa gactatcatc accaaggatt aggaacaaaa ctttttaaag aagcagaagg
    21241 ttacgcagca aaacattaca aatatttgca agtgaagact gtagacgagg ggcactactc
    21301 tatatatgat caaactattt gtttctacga atcattagga ttttcaaggt tggaagtttt
    21361 tccaaattta tgggatgaat ggaacccatg tttagttctt gtcaaaaaat tggaacaaaa
    21421 gtgagcaata gatttaatac taatctgtgc ttgatgaaaa ttctcactgt aaaaaatgct
    21481 gaaaatcaag tataatacca taggaacaaa ctggaaggtg aaaaagagca tggcacaact
    21541 attttttaag tatggcgcaa tgaatagcgg caagacgatc gagatcctaa aagtcgcaca
    21601 taattatgaa gaacaaaata agccagttgt cttaatgaca agcggtattg atacaagaga
    21661 tggtttaggc gttgtttcaa gccgaatcgg actgaaacgt aatgcgatgc cgatatttga
    21721 agaaacagac gtatttgacg taattcagaa aatggaaagc aaaccctatt gtgtgctgat
    21781 cgatgaagcg caattcttaa aaaagaaaca tgtcattgct tttacgagaa ttgtggacga
    21841 attggatatt ccggttatgg catttggttt gaaaaatgat tttcgaaacg agttatttga
    21901 aggatcaaaa tatttattgc tttatgcaga caaaatcgaa gaaatgaaaa caatctgttg
    21961 gttctgccac aaaaaagcaa tcatgaattt acattatatt gatggaaacc ctgtttatga
    22021 aggcgatcaa gtgcaaattg gcggaaatga agcttattac cccgtttgtc gaaaacatta
    22081 ctttcaccca tcaatgatta cagaaggaga ataagcatgt acgatcaatt acaagcaatt
    22141 gaagaccgtt atgaagagct tggagaactt ttaagtgacc cagaagtgat ttctgataca
    22201 aagcgtttta tgcagctttc aaaagaagaa gcaaacacgc gcgaaacagt cgaagtttat
    22261 cgtcgttata aagaagtagt acaaggaatc accgatacag aagaactgct tggtgaaaaa
    22321 ctggatgatg aaatggctga actagcaaaa gaagaattat ctgaattaaa aaaagaaaaa
    22381 gaagtcttag aagaaaaaat caagatcttg cttttaccaa aagatccaaa tgacgataaa
    22441 aatatcatca tggaaatccg tggagcagca ggcggagacg aagcagcatt attcgctggc
    22501 gatcttttca atatgtacca aaagtatgct gaagcacaag gctggaaaac agaagtgatg
    22561 gaagctaacg ttaccggaat cggtggatat aaagaagtga tcatgatgat caccggagac
    22621 aacgtatatt cgaaattaaa atatgaaagt ggtgcgcacc gcgtccagcg tgttccttca
    22681 actgaatcgc aagggcgtat ccatacttcc accgcaacag ttgtcgtgat gccagaagct
    22741 gaagaagtag agatcgatat tgaagacaaa gatatccgta cagatatcta tcatgcttca
    22801 ggtgctggcg gacagcacgt caataaaaca gcatctgctg tacgtttgac tcacttacca
    22861 acagggatcg ttgttgctat gcaagatgaa cgttctcaaa tcaagaaccg tgaaaaagca
    22921 atgaaaatct tgcgtgctcg tgtgtacgat aagatccagc aagaagcaca aagcgagtat
    22981 gatgccaatc gaaaatcagc agtcggaact ggggatcgtt cagaacggat ccggacgtat
    23041 aatttcccgc aaaatcgtgt gactgatcat cgtatcggat taactatcca aaaattagat
    23101 cagattttag cagggaaatt agatgagatc gttgatgcat tgatcatgta tgatcaaaca
    23161 tcaaaactgg aagctatgca aaatgggtaa aatgacctat cgagaagtcc tgtcacgggc
    23221 ttcttctttt ttagaggatc atgggaaaga agcatatagt atccaatttt tatttttgga
    23281 acgaaaacaa tggaaaaaac ttgattggct ccttcatatg aacgaagaga tttcagaaga
    23341 agaacagcgg ttgatcgaaa ccgatctgcg acttctgctt gcagatcatc cacctcagta
    23401 tttgctagga tatgcagatt tttatgatca tcggttaaag gtaactgaag caacactgat
    23461 ccctcgacca gaaacagagg agttagtcga atggtgttta gacgagacgc ctggtgtacc
    23521 gttagaagtg atagatattg ggacagggac tggagcaatt gctattagtt tgaaagcagc
    23581 aagaaaaaat tggcatatat ctgctgtgga tctttcagaa gaagcattag aagtagcgaa
    23641 agaaaatgct cagaaagaag gaacgaaaat cagtttttat catggagata cattaggacc
    23701 agtaatggat cagcaatttg atgtgattat ttctaatccg ccgtacatca gtcggaatga
    23761 atgggaactg atggatgaaa gtgtccggtc attcgaacct aaaatggccc tttttgctga
    23821 gaacgatgga ttagctattt atgaaaaaat agcagttgaa gcaccaagcg tactaaaatc
    23881 aaatggaaag atttttttag aaatcggatt tcgccaaggt gaagcagtaa aaaaaatatt
    23941 tcagcaagca tttccagata aaaaagtggc gataaaaaag gatctttttg gcaatgaacg
    24001 aatgatccaa gtttatggtt gaagttgtgg atgaaaaatt ttttatttgt ttttttatta
    24061 taaaaaaaca cttatttgac aaggatgtaa acgacttttt ggtttatcaa caagtttatc
    24121 cactattgac aaatagatta tccacaaaca gtggaaaact tgaggataaa ctcagacaaa
    24181 ataagaatgt atgaaaaagg ggttgtggat aaactgtgga aacgaaacga tatgatgaaa
    24241 cagaattgca agaggcagcc gaagcactga aagaaggaga acttgttgct tttcctaccg
    24301 aaacagtata cggattgggc gccaacgctc ttttaccaaa cgctgtcaag aaagtgtttt
    24361 ctgtaaaagg gagaccgcaa gataatccat taatcgtcca tgtcgcctct tttgaacaag
    24421 taaaagagta tgtggacaac tttcatccgg cagcagagaa gattgtgaag aacttctggc
    24481 ctggaccatt aactttgata tttaagatca aaaaagacac tttgccctca gttgtgacgg
    24541 gaggattatc cacagctgca tttcgtatac cggataacaa aaaaacacta gaagtaatcg
    24601 aactttccgg tgttccgctt gtcggtccaa gtgcaaatac gtcgggaaaa ccaagtccaa
    24661 cgactgcaga tcatgtatat catgatctac aaggaaaaat taccgggatt attgatgatg
    24721 gagctacgcg aattggtgta gaatccactg ttcttgattt aagtgatcca acagccatgc
    24781 ctatgatttt acgaccaggt gcagtaacga aagaacaaat cgaagcagtc atcgaatctc
    24841 ctgttgctat tgatcagcat cttgtaaaag aaaatgaaac accaaaagcc cctgggatga
    24901 aatacaaaca ctactcaccc gatacacgtg ttctgatggt cagagatggc gattggtcaa
    24961 ctgcagttca atgggcaaaa aataagaaga tccgtgcagg tgtcatagca agccccgaaa
    25021 ttgcggatca agtgcggaca gatactgcag ctgtttatat gtataacgac aactcagtag
    25081 aagcggcggc taaaggattg tttgcaggtc taagaggatt agatgaacca acacttggat
    25141 tagatttgat ttttgtacaa gtgtatccag aaactggatt ggggaatgct tacatgaatc
    25201 gcttgaaaaa agcagcagga caaaattatt ttgaaaaatg atcaattggt tattgtcgca
    25261 ttcttttagt atgatacaat gctatcaagt aaatcttcta tcagtgaacg aaaaactaag
    25321 cgtaactaat cgtaatagaa gagatacgaa tatttggcaa tttgtttttg atgggaaaaa
    25381 taaaattgta ggaaaataaa attgtaggaa aataaaaagg agctgttgtt tgtggtagat
    25441 tacaaaacgt ttgaccctga tctttgggct gcgatcgcca aagaagaaga aagacaagaa
    25501 cataatttgg agctgattgc ctctgaaaac tttgtctccg aagcagtgat ggctgcacaa
    25561 ggaagtatct tgacaaataa atacgcagaa ggttatccag ggcatcgcta ttatggtggg
    25621 tgtgaatttg tcgatatcgt tgaaaattta gcgattgacc gtgcaaaaga attattcgga
    25681 gcgaaatttg cgaacgtcca gcctcactcc ggctctcaag ccaacacggc tgcttatctc
    25741 gctttggtag aaccagggga cacgatctta ggaatggatc tttccgcagg cggacatcta
    25801 acacatggat caccagtcaa cttcagtggc aaaacctatc actttgttgc ttacggtgtt
    25861 gatccgacaa cagaagttat tgattataat gtggtacgta ttttagctag aaaacatcaa
    25921 ccaaaattga tcgtagcagg tgccagtgct tacggacgaa cgatcgactt tgcgaaattc
    25981 agagaaatcg cagatgaagt aggcgcaaaa ctgatggtag atatggcaca tatcgcagga
    26041 ttagtagcag caggacttca tcctaatcca gttccttatg cagatatcac aacgactacc
    26101 actcataaaa cattgcatgg ccctcgaggc ggcatgattt tgacaaacga tgaagcatta
    26161 gcaaaaaaaa taaatagtgc ggtatttcct ggtattcaag gcggccctct agagcatgtg
    26221 attgcgggta aagcagtagc attcaaagaa gcattagatc ctgcatttaa agaatatagt
    26281 gaacaaatca tcgccaatgc aaaagcaatg gtcaaagttt tcaatcaagc aattggaacc
    26341 agagtcattt caggggcgac agataatcat ctgatgttga tcgatgttcg cgagttaggt
    26401 ataaatggaa aagaagcaga gagcattttg gacagtgtga atatcactgt aaataaaaac
    26461 tcgattcctt ttgaaacact aagtccattc aaaacaagcg gtattcgaat cggcacgcca
    26521 gcaatcacta ctcgcgggtt caaagaagaa gatgctgtaa aagtggctga actagttgtc
    26581 aaagcattac aagcaaaaga tgataacgct caactagacg aagtcaaaac aggtgtacgc
    26641 gaattaactg aaaaatttcc gttgcataaa aaataaaaat ttaaattcca ttagtaaaca
    26701 gaaaagttca atgttgggct tttctgttta ttttttggga aaacggattc tttgacaata
    26761 tcggtgatgc tctctagtat atgaggtgta attttagtct tcacactaaa tctcagggag
    26821 gaaaagtcat gactgatcgt atctcgttag aaaaggaagc agtagcattc agtgatgcaa
    26881 atgcgcctca tccgcgtatc tatgaactag caccggaaga aggaagagtt ttactagaag
    26941 aagtacaaga atcacctgtg aacaaatatt ccgtcgatat tgaagacttg atggtggata
    27001 ctggcgaatg gggaaaactc aatattcgtc tcgtacgacc agaagggaat atggataaat
    27061 taccagttat tttttatatt catggagcag gctgggtttt tggcagtgct caaacccatg
    27121 ataaattgat cagagaactt gcggttcgta cgaattccgt cgttgtcttt ccagaatata
    27181 gtcgatcacc agaagcaaaa tatccaacag caattgaaca aaattatgct gtgttgcaac
    27241 agctgaataa attagccaag tcaaaaaatc tggatctcga gaatctaatc gttgcaggag
    27301 attcagtagg tggtaacatg gctacagtca tgacgatctt aacaaaagaa cgaaagggcc
    27361 tcccaatatc caagcaattg ctgtattatc cagtcacaaa cgctgatttt gatacagatt
    27421 cctatcatga attcggagaa aactattttt tgacaagaga aggaatgatg tggttttggg
    27481 accaatatac gacgaatgaa gaagagcgtg ctgaaatcac agcttcgcct ttgagagcaa
    27541 atataaatga actaaatgat cttccttcag caatgatttt aacgggagaa gcggatgtat
    27601 taagagatga aggtgaggct tatgcgcgca aacttcgtga tgcaggggtt cctgttacac
    27661 aagtacgctt ccaaggaatc atccatgatt ttgtcatggt aaatgctatg gatcagacaa
    27721 aggcaacgcg tgcagcaatg gcattatcta cttcttggat caagaaaaaa gaataagctt
    27781 tgcttgtccg caggaaaact tcttttcaaa aacggatttt cttaggaaaa atggcgagtt
    27841 tgactagtca atcacttgat tttgttttac aattaaaaag aaacgacaga acaaaggaga
    27901 gcttaaaaaa tgggcaaatt tcaagtgatc gatcatccat tgattcaaca caaactaact
    27961 attattcggg acaaaaactg cggaacaaag gtttttcgtg aagtagtcga tgaaatcgct
    28021 atgttgatgg catatgaagt atcacgggat atgccattgg aagacatcgt gatcgaaaca
    28081 ccgatcactg aaacaacaca aaaaacgttg tctggtaaaa aagtagcgat tattccaatc
    28141 ttgcgcgcag gtattggaat ggttgacggt atcttggaat tgattccagc tgctaaagtg
    28201 ggacatatcg gtctttatcg agatgaagaa acattggaac cacatgaata tttcgtcaaa
    28261 cttccagaag acattgatgc acgtcagttg tttgtagtag atccaatgtt ggcaacaggc
    28321 ggatcagcaa tcatggcaat cgatgcattg aaagaacgtg gcgcgtcgaa cattaaattt
    28381 gtttgtttgg tagcagcacc tgagggagta aaagctttgc aagaagcgca tcctgatatt
    28441 gacatctata cagcttctct agatgaaaaa ttgaatgaac atggttatat cgttcctgga
    28501 ctaggggatg cgggtgaccg tttgtttggt acaaaataag taaatacgaa aaagggtgtg
    28561 acacaacttt tgtcacatcc ttttttggtc atttttaacg tttgatgcag aacagctttt
    28621 tcacagcttt cgtttgcata taaaaaaacc atcccaaaaa tgcagagatg gtcaaattca
    28681 aatctttttt agttctttgt agttaacgat tactacaccc ttactttgcg tcatcaagtt
    28741 cgcattttct gcagtttcat caatctcaac aacagcggaa tttttcaatt gctttgaaat
    28801 cgttccagtt tgcgacttgc cgtgaattgt gaacattacg tgagtattga tcttgaattt
    28861 ttcaccaatt tccgatggta cgatagttgt atcaaatttt ccaaaagttg ccattttcat
    28921 aaaacctgtc tttcacatca attataccac gttttatgaa aaatatcatg aaattaaact
    28981 aattttccat cggactcttt acaatcagcc aaatagagta tataatttct tttggataag
    29041 gccagcttag ctcagttggt agagcaacgc actcgtaacg cgtaggtcgt aggttcgatc
    29101 cctatagctg gcattaaaag agaagacaga tatatcaagg atttttaatc cattgataca
    29161 tctgtctttt tgtttaaagg aaataaagta tgctttctta gcaatagagc atgtattatt
    29221 tctataaaaa tttaggagaa taaaacgact agcaatatag ctgtgaaatc aaatatcaca
    29281 tgaactgccc aacttgtaat gatcgagttg cttttaatgg cagcttggtt gaataacaat
    29341 cttgccaccc cttgtatcaa aaggatgtgt gctacagtgt gtaaaatatt tccattatca
    29401 taagtactgt aatggataaa tccaaagatg attgctgaca agaaactagc gacaggaatg
    29461 ctgaacttac tagaaaaaat agcgagaaaa tacactgaga acaattcttc tccaagtatc
    29521 atgataggca aaataataaa taataacggg ctgaaagcct catttattgg attgcctgtt
    29581 aaaccccatt tcaaaatttg ttgcaaaaat accgagactg cggcactgat tactacattg
    29641 ataaaaaaat atttggctat atttttgaca ggagcgacag gtttcgagaa catttttttc
    29701 gtatcttttt taccaaaaac aagtgtaaat gctataaatc cagtgatagt taaagaaaaa
    29761 atgctaataa tggatggcgc aaatagcaac cctaacaaac cgagtacaac gacaatagtg
    29821 cccaatatcc cttttttaag ttctattttt tttcctaaaa tgttattcat gataataact
    29881 cctactattc agtttttgaa gatagagtca gtatacatga agagttaaaa taggcaatgt
    29941 ttttttatgg atatttgtat tgctaaaaat ttatcttata tattcatttt gattatacta
    30001 cttttatttg taaaaatttt ctagcaaaac caagtgcttg caactgatta agcgtacaat
    30061 tttttagatg ttccgagcgt acttcaatca tttcaaagga gttgctactt aaatcgatat
    30121 tttttaaatc agtatcaaaa aagctagcat tttctaaatc attagtagaa aacattattt
    30181 tagtgaggga acagtctaca aaatctgcgc ttgataagac agagtgctca aaggtacttt
    30241 cttttatgtt tgaaccagat aaatttacat agtccatttt acaattctcg aataacgtgt
    30301 tcccaatata actttccatc aatttagtac ctgttaattt acaattgaca aatttcacgc
    30361 gatgcaacat gctttttgtc aatatacagc ctgaaaaatc acagttttcg aatatacagt
    30421 cggtaatctc cattctttga aaatcattgg aagcaaaaaa tgcatacttg aaaatagatt
    30481 tgtaaataat tggatggcag attatttggt tttcgatgac ctctttttgt gaaaggatat
    30541 tatacagttc aaaatcttcg ttttcataga tatgaaaaaa ggatccttta ttcaagcttg
    30601 cttcattaac tttaggaaaa atcatattta attacctcca ttttcataaa gtcatattaa
    30661 caaaagctaa accaacttac attagcagaa aatgagatag gttttcgcct ttttcgataa
    30721 cgatagtgtc gctatctctt gaaacgttct tagaattgcc ctgagagaca caaattaggc
    30781 gtaattctaa taaaaatctt agaataaaaa tttttactga tttaatttag aatgttttta
    30841 aaataaaaat cgttgccata acagtgtatt gaaaggtttt aacaatccag taatgattta
    30901 aaaaaatcta gatgtagcgt atactttgtt tatagaatgt agtgggaaga aatatatttt
    30961 tgggaggaaa tcgtgatgtc taaaagtgaa gaaatagaaa acatggtact aaaattatat
    31021 gatctcgttt taaatccaga gatcaaagaa aaggaacgta tacttttgat agacgcaaag
    31081 acaggcttag aaaaaggtca gtattatcct aaagtcataa ataatttgga acgtagttta
    31141 cgtccgttag caatcagggg agaattgtct aaaccagtat caccgtttta tatggagata
    31201 tcaacaatag gaaaatttga aaaagaatta ggtcgaggaa tggcttcggc accgattact
    31261 tttgggcatt tataaaaacg agttattcat ctcaatgaat taaaaagtat agtcaatctc
    31321 ataatgcagg ctaggttcat ttatttgaac agagtctgta tttttttatt ctaaataaag
    31381 aaacagatgt ttctttatat tgtattttat cctttaatta acacaaaaac
//
LOCUS       DACCVZ010000026        30765 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.026, whole genome shotgun sequence.
ACCESSION   DACCVZ010000026 DACCVZ010000000
VERSION     DACCVZ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.026"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            570..1898
                     /locus_tag="IVW63_001226"
     CDS             570..1898
                     /locus_tag="IVW63_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAP7859509.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2100..2933
                     /locus_tag="IVW63_001227"
     CDS             2100..2933
                     /locus_tag="IVW63_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAP7859510.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2949..3686
                     /locus_tag="IVW63_001228"
     CDS             2949..3686
                     /locus_tag="IVW63_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HAP7859511.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3841..4809)
                     /locus_tag="IVW63_001229"
     CDS             complement(3841..4809)
                     /locus_tag="IVW63_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAP7859512.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5041..5874
                     /locus_tag="IVW63_001230"
     CDS             5041..5874
                     /locus_tag="IVW63_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAP7859513.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5908..6747
                     /locus_tag="IVW63_001231"
     CDS             5908..6747
                     /locus_tag="IVW63_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7859514.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6773..7333
                     /locus_tag="IVW63_001232"
     CDS             6773..7333
                     /locus_tag="IVW63_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP7859515.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7532..9253
                     /locus_tag="IVW63_001233"
     CDS             7532..9253
                     /locus_tag="IVW63_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAP7859516.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9418..10560
                     /locus_tag="IVW63_001234"
     CDS             9418..10560
                     /locus_tag="IVW63_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP7859517.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10576..11787
                     /gene="thiI"
                     /locus_tag="IVW63_001235"
     CDS             10576..11787
                     /gene="thiI"
                     /locus_tag="IVW63_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAP7859518.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            12360..13007
                     /locus_tag="IVW63_001236"
     CDS             12360..13007
                     /locus_tag="IVW63_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAP7859519.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     gene            13400..16045
                     /locus_tag="IVW63_001237"
     CDS             13400..16045
                     /locus_tag="IVW63_001237"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAP7859520.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            16355..17668
                     /locus_tag="IVW63_001238"
     CDS             16355..17668
                     /locus_tag="IVW63_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAP7859521.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            17658..18311
                     /locus_tag="IVW63_001239"
     CDS             17658..18311
                     /locus_tag="IVW63_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP7859522.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            18366..19058
                     /locus_tag="IVW63_001240"
     CDS             18366..19058
                     /locus_tag="IVW63_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAP7859523.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            19208..19408
                     /locus_tag="IVW63_001241"
     CDS             19208..19408
                     /locus_tag="IVW63_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP7859524.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(19662..21341)
                     /locus_tag="IVW63_001242"
     CDS             complement(19662..21341)
                     /locus_tag="IVW63_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAP7859525.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(21343..21555)
                     /locus_tag="IVW63_001243"
     CDS             complement(21343..21555)
                     /locus_tag="IVW63_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAP7859526.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            21948..23678
                     /gene="efrA"
                     /locus_tag="IVW63_001244"
     CDS             21948..23678
                     /gene="efrA"
                     /locus_tag="IVW63_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAP7859527.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            23675..25435
                     /gene="efrB"
                     /locus_tag="IVW63_001245"
     CDS             23675..25435
                     /gene="efrB"
                     /locus_tag="IVW63_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAP7859528.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            25530..25727
                     /locus_tag="IVW63_001246"
     CDS             25530..25727
                     /locus_tag="IVW63_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859529.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            25880..26365
                     /locus_tag="IVW63_001247"
     CDS             25880..26365
                     /locus_tag="IVW63_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAP7859530.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(26469..27062)
                     /gene="clpP"
                     /locus_tag="IVW63_001248"
     CDS             complement(26469..27062)
                     /gene="clpP"
                     /locus_tag="IVW63_001248"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAP7859531.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            27242..27769
                     /locus_tag="IVW63_001249"
     CDS             27242..27769
                     /locus_tag="IVW63_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAP7859532.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            27860..28597
                     /locus_tag="IVW63_001250"
     CDS             27860..28597
                     /locus_tag="IVW63_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAP7859533.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            28601..29518
                     /gene="miaA"
                     /locus_tag="IVW63_001251"
     CDS             28601..29518
                     /gene="miaA"
                     /locus_tag="IVW63_001251"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAP7859534.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            29520..30749
                     /gene="hflX"
                     /locus_tag="IVW63_001252"
     CDS             29520..30749
                     /gene="hflX"
                     /locus_tag="IVW63_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAP7859535.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10156 a         5264 c         6564 g         8781 t
ORIGIN      
        1 aatccaatca cttgggtttc tttttctttt attattatga tgaatcaagc tttctgtttt
       61 tgtcacgtat gttgtaatct ttacgaaaga gtagagttgg ctactcataa tcaaccatac
      121 ttcccatcat cgctaaatac gaaataaatc agcattccta caccaatcaa agcacaagct
      181 gcaccaagaa aagggatgac attcccaaag ttatctgtat tcataagtat gccaccaccc
      241 acaaacaaaa agccgccagc aatcaggttt ttcattttat tcatctcctt tcttacgtta
      301 tagtatttcc ttctttcaat gagtattttg aaagctatct tattgtatga tgttcttcta
      361 ggcctcttct ttattataca ggccattttc gttatctcat agaaatattc ctttttatct
      421 gaaaactatt gtataccgta tgacattttt cttcatgaag ttgtaagtat attctcattc
      481 aaatgaaaat ttcatcatag aagagattgt atttctaaat tcttaagagt aaaatacgaa
      541 gtataacttg gatttggaag gatgattgga tgaaagctat tacgcctgat atgacaacaa
      601 aatttaacaa acagtttcaa gcaaatatca aacagcaggc attgcagcgg gcagttgtga
      661 agaacggaat tactgcttct gctgaaaatg tttcagcaca tgtggagaat acaccggtat
      721 tttctataga tttggctacg gggaaagtgg ctaatcaaat gcaatcgggg cgttgctgga
      781 tgtttgctgc actgaacaca ttccgtcata agatgctgaa tcaattccat ttaaaagagt
      841 ttgaattatc acaaaattac acttttttct gggataaata tgaaaaggca aattatttct
      901 atgaaaacat cattgcaaca ggaaaagagg caatcgatag ccggaaagta gctttcttac
      961 tcgctactcc tcaacaagat ggcggccaat gggatatgat cgtttcatta ttccaaaaat
     1021 atggcgttgt gcctaaatcg gtgatgccgg aaagtgcgaa tagttcaaat tctcgagatt
     1081 tgaataacta cttgaacaaa ttactgcgta aagatgcagt agtgttacgg aaaatggttg
     1141 ctcaaggaga aacattagac gctattgaag aaaagaaaga agaaatgcta gaaagcattt
     1201 ataacttctt agctatctca ttaggaacac ctccaaaaga attcgatttt gagtaccgcg
     1261 atgaagaaaa gaactatcat cttgaccgag gactgacacc acaaattttt tatgataaat
     1321 acatcggtgt aaaattagat gattatgtta gcgtgatcaa tgcaccaaca aaagacaaac
     1381 cattcaatcg ttcttataca gtagagatgc taggaaatgt cgttggcggg aaagaagtca
     1441 aatatctgaa tgttgatatg gaaactttca aaaaattagc gattgctcag cttgaagaag
     1501 gagaatctgt ttggtttggt tgtgatgtag gtcaatcttc tactagaact agtggcatca
     1561 tggccttaga tgcttattca atggatgatc tatttgatac ggattttaca atgactaaag
     1621 ctgaacgttt agattttgga gaaagtctga tgacccatgc gatggtattg accggtgttg
     1681 acttagtaga cgggcaatca acaaaatgga aagtcgaaaa tagctggggc gaaaaagttg
     1741 gaaagaatgg cttctttgtt atgagtgatg cctggatgga cgaatatacg taccaaatcg
     1801 ttgtaagaaa agatttattg acgaaagagc aattaaatgc gttcaatgaa gaaccaattg
     1861 ttctatctcc gtgggatcca atgggtgctt tagcatagac gagtatttca atgaagagta
     1921 tgtagtaaag ataaaaagag ctggcttaag ccagctcttt ttatctttaa agtccattcc
     1981 ctgtttttta tggtccctgt gctataattc taaataaagg ataaggattg gaaataatcc
     2041 ttttatcatt aaaaatatga tgacgaagta gaataaaatt gggagtaggg gggaaagtca
     2101 tggatatcca aactgtttta tctgatctga aattaaatgg taaagtgatt ccagttgttg
     2161 gtggcgatgt taatcagacc tatcgtataa aaaccgaaca tcgtgcttat tttttaaaaa
     2221 tccatccgaa tgtaaaaaaa ggattttttg aagcagaagt agacggatta aaagaactgt
     2281 cagcattcgt acgtgtaccg gatacgtata tgctaggtga aacaagtgaa ggcgcttatt
     2341 tgttaatgga atggatcgag ccgggaaaag gggatcaacg agatcttgct gcagctttag
     2401 ctaatctcca tcagcaaaca gcgccacaat ttggttttcg taaagataac tatttgggta
     2461 cacttgttca gaaaaattct tttgaagaag attggtggac ttttttcttt aaagatcggc
     2521 ttgaatccca gatttctttg gcagaagaaa cgaatcgatg gaatgtacag cgtcaagaaa
     2581 agtatctgcg atttaaagaa cgtgtattga aatcggttga accaaaaaag atcactccac
     2641 gcctcttgca cggagacctg tggagtggta atgtgttctt tgaccagcaa gggcatccag
     2701 tttttgtcga cccagctgtt tcttatggga atcgggaaca agatattgca atgagccagt
     2761 tattcggtgg tttccgaccg gaatttttag atgcttatca aactatattt ccattagaaa
     2821 agggatggaa agaccgactg ccgatttacc agttatatta tcttttggca catttgaata
     2881 tgtttggaga aagttacggt tcccaagtag atcaattact agaaaatttt taagaggagg
     2941 gcgtgttttt ggcaaaaaaa tataccaaaa agcatgaagt ttcatattat gagtgtgaca
     3001 tcaaccaaac gatgacattt ccttcgatgt taggagtagt tatcaaaacg tctgaagatc
     3061 aaagcgacca gttgggaaga ggcagtgaat tcgtcaatag ctttggactt acttgggtca
     3121 tcacgaatta ttccatggag attaatcgtc tccctagagt cggtgaagta atctcagtaa
     3181 cgactcaagc catggagtac aataagtttt tctgttatcg gaacttctgg atccatgatg
     3241 aagatgggaa agaattagtc aaaatagaat ctgttttcgt attgatggat tttgtgaatc
     3301 gaaaaatgag cagtgttaat gaagagatca ttgctccttt tgagagtgag aagatcaaga
     3361 aaatcaagcg tcaggaaaaa attgaaaaga ttgattcggg cttcatgttg ccatatcgtg
     3421 ttcgttttta tgatatcgat agtaatcagc atgttaataa tgcgatgtat tttaattgga
     3481 tcattgacgt attaggatat gactttttga ctacgcatgt tccagaaaaa gtaattattc
     3541 gatttgataa agaagtagag tacgggaatg agatcgaaag ccattttgaa caaatcccta
     3601 tcgaaaatgg tgtcaaaaca aaacatgaaa tccgaatgca agaacagctg tattgtgaag
     3661 caaatattat atggaaaaat aaataaaaaa gaggttgtga cagaaggggg caacttcaag
     3721 aaataagaag aaatttacga aaattgtttc tcaaattttt gtaaattttc gacttagttt
     3781 tcgaagaagc tatttttgtc acagcctctc tttttaagtt tagctattag ataatgatgt
     3841 ttagttttgg ataaacgaaa tcaattcttc acccgacaaa ccatagttta cagcaatcaa
     3901 tagttttaaa cgtgcttttt gactattaat actgttacag aaaataatcc ccattttttc
     3961 tagttctttt cccccgcctt cataatcata aacaggctct gcgattccat tgaaacaacg
     4021 agaaacaagt actacaggga ttttttggac aagaagcttt tccaaagcag ctaaggcttg
     4081 tggagggaga ttccccgcac ctaaagcttc gattaccaaa ccgtctactt tcgtatgggc
     4141 gatggcttcc aataagtccc cttgcatccc agcatatgct ttaacgatcg ggatagtccc
     4201 atctacagcg gaaatgtcca gtcgctttgt ttctaaaagt tcctgcaaga ataaaattcg
     4261 attcttagtt actaagccga tgggacccaa tgtaggtgtt cggaaagtag caacatttgt
     4321 ggtatgggtc tttgtcacgt agcgtgcaga atggatctca tcgttcatga ccaccaaaac
     4381 ccccttatct agcgcttctt cacaacttgc gacacgaatc gcactttcaa aattataaag
     4441 gccgtcactt ccaagttcat tacttgaacg cattgcccca gtcaaaacaa ttggtaattt
     4501 gttgccaatc gttgtatcaa gaaaaaaagc agtttcttct aatgtatctg taccgtgtgt
     4561 gatcaccact ccggatatac ctgatgcata agcggacaag atacgttctt ttaataccaa
     4621 catgtgagaa ggcatgatgt gtggtgaggg aagattgaag atatcttcaa ctaataattc
     4681 tacatgcttg gggattgtga tttctgcatc taataatggg tttgccacat caggactaac
     4741 accgcccgtg agcatgtttt ctttcatggc gatcgttccg ccggtgtgta gtacaagtat
     4801 ttttttcatt ttacagactt ccttacgaat aattttgcat agccgttaaa tcttattgta
     4861 tactatataa aagagttttg ctatcagtga agaataacga atagcctaac ttatcataaa
     4921 aaagctgacc ttattaaaat ggaaaagact caaccttgac ctcctaatac aatggagtat
     4981 ctggttgagt ttcttttaca agaaagcagc caaggaaatc aatcacgaag gtggccggaa
     5041 atgatcagaa tcggattaac atcgtttaaa gaacatgaca aattaactgg taaaaagaat
     5101 aacactcttt atgaatatgc agggtttcta cccttagtgg aattagatac tgcctattat
     5161 ggaattcccc gaaagtcctc agttgagaat tggataagtg aagtacctga atcatttcgc
     5221 tttgtagtca aagtctatca aggaatcagc ggtcaaggag actggaagcc ttattatcag
     5281 accgaagaag agatgattgc gcatttttta gatgttatgt cgccaatggt agatgctgga
     5341 aagatgtttt gctttttagt ccaattcccc tcatcattca aatgtacgaa agaaaatgtc
     5401 cagtacttgc gcaaacttag aaagtggttt gagggttatc ctgtttctat agaattgcgg
     5461 gattattctt ggtacagcga tgaatttctt gaacgtacaa gaaactttat gtctagagcc
     5521 gctttttctt tagccatcat cgatgagcca cagttgctga atacaacgat tccttttgat
     5581 ccatttgtca ccaatccgaa ctttgctctt tttcgattcc atggtaggaa tgcgcaagga
     5641 tggcaagcaa atgataaaga gtggcgtaaa aaaagaacgt tatatcgtta ttcagaaaaa
     5701 gaactgcaag aactagcaca tgaagtcaaa gtagttgatt ctaagacaaa agaggtaggt
     5761 gtgattttta ataataattc tggtggtgat gcggctgaaa atgcattagc actgcaaaaa
     5821 atattaaata tcaagccaga tggactcaat ccaacccaaa tggatctgtt ttaagggctt
     5881 attttattca agaaaggggc gaagtctatg atcaaagcta ttttttttga tattgacgga
     5941 acattggtca ccaatcgttc aaaagcgttg gaatcaacaa aacaagcaat tgaatatgct
     6001 cggaaaaacg gcattttatg cggtgtagca acggggcgca gcccagtaaa gatcaaagaa
     6061 atcattgatg aattggaatt agatatgtat gtcgtgtata atggtcaact ggtttttact
     6121 gcagatcgca cgattatcga ccaccctttt gaacaaaaag tattggaaca tattgttgaa
     6181 tttgcagatg agaaccatcg acaaatcgtt tttggtgcga gaaatcggtt agatggatca
     6241 acgacgatgc tattaggaca atcgattttt atcaagcgac tagtcagctt tttaccgcgt
     6301 aaattcccgg tacgtctgat gaaaaaaatc ctccaggttt ttagccctca ccgacaaaag
     6361 gatcgttatg aaacgttaga gatattaaaa gaaccaattt atcaatgtat attgctcagt
     6421 ccggagtcag aacagaaaaa gttagaacat cgctttcccg agtgtacgtt tcagcgttca
     6481 aatacgtata ctgtagatat catcccaaaa ggtggttcaa aattactagg catccaagct
     6541 ttcgcaaatg ctgtcgaaat tgaaatggaa gaaattatgg cattcggcga tcattacaat
     6601 gatatcgaga tgctgaaagg tgtaggaatt ggagtggcca tggggaatgc tcagatcgaa
     6661 gtaaaacatg ctgcagactt tgtgactcaa tcaaatgaag aagatgggat atacgaagga
     6721 ctgaaacact tcggtctgat ttattagtca atgaaagaag gaaaaaatca gtatggaagc
     6781 agagacacct tttcaaaaag tagaaacatt ccacaaaact tttgatccaa gaagaccaga
     6841 gatacccacg gcttttacag aaaatgaagc tcatacacgt gctgcgttca aaatagaaga
     6901 acttgttgaa tttgttgcag ctacttcacc taataaagaa caactgcatg aagctgttat
     6961 gctgctgcac gaagcattag ataaagcaga agaaaaaata cttggtaaaa cacagtgggg
     7021 aagtgatccg ctggttgaac aagtagatgc actgacagat atcctttact ttacttatgg
     7081 ttctttttca ttactaggaa tagtgcctga tcgaatattc gaaatcgtcc atcaggcaaa
     7141 tatggggaaa ttatttccag atggaaaacc tcattatgac cctgtaacaa ataaagtgtt
     7201 gaaacctgaa aactggcaga tggaatatgc tccagaacct aaaatcgcgg cagaaatcca
     7261 acgtcagatt caagaagcga ttgctaagaa gaaatccgct gatataggca tgtgcacaaa
     7321 tgaaaaagag tgatcagagt ttcactattt ttgttatctt tatacgatgg aaaaacaaaa
     7381 gattttcgtt taagttagtg aatgcatgaa aatagtatgc tataatctag aatagatgtc
     7441 ttttgcacga gagacgtatt atttggattt atgccaagca gaacgccatc tgttgcataa
     7501 aagatgcata ctgaaaacgg aggaaccata aatgggaaat aatgttatca tcggaatcgt
     7561 cattgcaatc attatagtcg ccattgtcgt ctttttggtt agttacttga tgaagaaaaa
     7621 aaaccaagat cgattggatg ccttagaaaa acgcaaggaa gaattatttg acttgccagt
     7681 gattgaagaa gtcgatgatg ttaaaaaaat gcatctggtt gggcaaagcc aaaatacctt
     7741 tcgtgaatgg agtcaaaaat ggaatgacat atctacttcc tcgttcgctg aactagaaag
     7801 tcaaattttc gaagtggaaa acctcaatga aagttttcgg ttcttaaaag gaaaaaaagc
     7861 agttgttgaa gcagaagcta caatggacca aatggagaaa caagtgacgg aaatccgtga
     7921 aggtctaaag gaattgcggg aaacggaaga acgcaactca ctagctgttc agcaggcact
     7981 tgacgtctat gaagaactga aagaaaaagt cagagaagac gagcatgaat acggaccagc
     8041 tctttttgaa ttgcaaaaac agatcaaagt gatcgaaaaa gaatttacgc agtttgtgac
     8101 tttaaacact tctggagacc ctgttgaagc ccgcgaggtt ttggataaag cagaaaaaca
     8161 tacgtatgaa gtggaagctc tgatgaaaaa aattccaccg ctgtatgagg agctccatac
     8221 cactttccct gaacaacttg aagaaatcag tgatacttac gagaaattga tggaagaaca
     8281 atatgtattc ccagaagaag atcttgctga agatatcgca aaagtaagtc gaagaattga
     8341 aaattcatta gccaatcttg aaaaaacaga agttgaaacg gtcgaatttg aaaaccgtga
     8401 aacagctgat ttgattgatt cgttatatga tatcttagaa cgggaaatgg aagctcagag
     8461 atatgtaaaa actaaccaat caacgattgc agagtatatc aaacatacaa caaagaataa
     8521 ccgtcaatta ttgattgagc tggatcacac atctcaaagc tatacattga accacaatga
     8581 aattggccgt gtacgaggtt tccaaaccga agtggaagaa atggaacgtc aaaatgaaca
     8641 gatgattcca cagatccgtc aacacgaaat tccttattca gaagtgcgca cgttctataa
     8701 aacagtcttc aaagtcttag aagatatcga aaagcaacaa gtagagatcg acgactcatt
     8761 acatgaattg agaaaaggcg aaaaagaagc gcaagaaaag atcgatacat tcgaattcaa
     8821 attgcgcagt ttgaaacgtt ttgtagaaaa acaacgtttg cctggcttgc cgaatgatta
     8881 cctagaattc ttttttgttg ctactgaccg tattgaagaa ctaagtgttg tcttgaataa
     8941 aattcgagta aacatggaag aggtcaatcg tttagttgct ctatgtgaag aagatctaga
     9001 attattagat aagaagacac atgatttagt agatgcagca gcattaacgg agcaaatgct
     9061 ccaatatgca aatcgttatc gtcatacaca cgaagaagtg agagaagcaa ttgataaaag
     9121 ctactattta ttcaataaag aatatcacta tcaagaagca ttagacgaaa tcggtacagc
     9181 attagagcga gtagaacctg gtgctttcaa acgcatcgaa gatttttatt ttaatcatcc
     9241 agacttagta taaagcaaaa aagttagtaa accagcaaga gcaagacgga ttattgtctt
     9301 gttcttgtct ttttttgtat atttgaaaat tgaaacaagt gaaaatttca cctgctcttg
     9361 aaagcacctt ggacaaccgt tataatagaa aagaatttca aaaaagaggg gtttcttatg
     9421 atatattttg ataacagtgc aacaacccca atctttccgc aaagcttaga tgcatatgta
     9481 aaaaccagtc agcggattat tgggaatcca tcaagcttgc atgatttagg caatcaagct
     9541 aaccggttgt tgcagcaagc aagaaagcag atcgctgatt tgatccatgt agaaccagaa
     9601 gaaatctatt ttacttcagg cggaacagaa ggagataact gggtattaaa aggaacgatg
     9661 atcgaaaaaa gagaatatgg gaatcatatg atcatttcag gagtcgaaca tccggccgtc
     9721 agcgagacag cagaacaatt aaaagaatta ggaatcgaag taagtatcgc cccagtggat
     9781 aaacgcggat ttgtacgtgt cgacgaattg aaagaattaa taagaaaaga gacagtatta
     9841 gtctctgtta tggctgtgaa taatgaagta ggatcgattc agcccatcca ggaaatcagt
     9901 gatcttttgg atgattttcc taaaattcat ttccatgtag atgctgttca ggcgattgga
     9961 aaagtaccat tctcgcaatg gttgacagaa agagttgatt ttgcaacatt ttcagctcat
    10021 aaattccatg gcccacgggg aactggtttc atttattgga aaaagggtcg tcgtttagca
    10081 ccattactga caggtggagg gcaagaaaga aatcagcgaa gtgggacaga aaatgttcca
    10141 ggtattgtgg ctatggttaa agctttacgt ttatcattag agataaagga acaaaaacct
    10201 gagcagacac aacgcttaaa agtagctcta atcaatgcgt tgaagacgta tgagaaagtg
    10261 acgatttttt cagaaggaac tgactatgca ccgcatattt tatgttttgc tctaaaagga
    10321 attcgcggcg aagttctcgt ccatgcctta gaagaaaaac aaatatttgt ttctactact
    10381 agtgcctgct cctcacgtaa acatatggca agcagtacat tgcacgcaat gcatgtacca
    10441 aatgatctgg ctacatctgc tgttcgaatc agcttagatg aaaacaattc gcttgcagaa
    10501 gtcgagcaat ttatgattat tttcaagcag ctttataaga aattttctgc aatcaattaa
    10561 aagaggagtg ttcttgtgaa atacagtgaa attatggtcc gttatgggga actttcgaca
    10621 aaaggaaaga atcgaaaaag ctttatcatg caactagcac aaaatgtcag acaagctttg
    10681 aaagactttc cagaaatcaa aatccatgct gatcgggacc ggatgcatct tttattgaat
    10741 ggcgcagacg ggcagctagt tattccaaaa ctagcaaaaa tatttgggat ccaaaatttc
    10801 tctccaagta ttcgtgtaga aaaagatgtc gaagttttga aacaagctgt tcaagacatc
    10861 atgaaagaaa tttatactgg gaaagaaaca tttaaaatta tcgctaaaag aagcgatcac
    10921 caatttgaat tgacaagtaa tgaattgaat caaacattag gtaatgctgt ttttgatatt
    10981 ttcccgcata tccaagttca aatgcgtcaa ccagatattc cattacgtgt agagattcgg
    11041 cgtgatggcg cttatctatc gtatgaaacg atcaagggag ctggaggatt gcccgtagga
    11101 acaagcggaa aaggaatgct tatgctttct ggggggattg attctcctgt agcagggtac
    11161 tttgccatga agcggggagt ggaaattgaa gctgttcatt ttgctagtcc gccgtataca
    11221 agtgaacaag cactgcaaaa agcaaaagat ctaacagcca aactagcacc ttatgtggga
    11281 acgatccatt ttatcgaagt gccatttacc gagattcaag aagaaatcaa aaagtcagtg
    11341 ccacaaggat attggatgac aattactcgt cgaatgatgt tgcgtttgac cgatgaaatt
    11401 cgccgtattc gtcatggttt agtcattttg aatggtgaat cattaggtca agtggcttca
    11461 caaactttgc aaagtatggt ggctatcaat gaagtaacga atacgccaat cattcggcct
    11521 gtagcgacaa tggataaact tgaaatcatt gaagtagcag aacagatcga tacatttaat
    11581 ctttctatcc agccttttga agattgctgt acgatttttg ctcctccaca gccaaaaaca
    11641 cgccctcaac tggaaaaggt ccatcaatat gaagagcgtt tagcaataga tgaaatgatc
    11701 caacgagcac tagctggctt gaagatggaa gagatacaag cagaatcgtc taatgaaaaa
    11761 actgaagaat tttcagaatt gctataagag gttatgaaaa tagtgttttg accagagtat
    11821 tagagaaaca aaacgaaaaa atagctccat gtattttacc gtttttgaac taatgtcgaa
    11881 gattagctga ttgaatacca tttatcaaga agttatggaa aagccggttc ttttttacta
    11941 actgaaaaat aaaattttat ttagagatca agctacagtt gataaatgat ataaaaaaga
    12001 gaatttccca tgaaatagcg aggttgtgac agaagtgggc agcttcaaga aataagaagg
    12061 aatttacgaa aattgctttt caaatttttg tgaaatttcg gcttattttt cgaagaagtt
    12121 acttctggaa caccgtgtat cagaggttgc gaaaaagctg ccctgcatca agtaataaga
    12181 acagccaaac aaaaatagtt cctcatattt tacgtttggt tgagcttatt accgcagatg
    12241 caagcttttg aacaccgttt tatttgtctc acaccctttt ccttcctact tgtaaccttg
    12301 ctcccgtgtt agaaacatgt tacactaaat atgtgaaatt attaacaagg agcgtcgtta
    12361 tgcgagaaaa aacagataca ctgccaaaag caactgcgaa aagattacct ttatatttac
    12421 gctacttgaa gatgctggat gactcaggta taagtagaat caaatcaaat gagttcagcg
    12481 aaatcaccca aattccttct gcaacgatcc gcagagactt ctcgcaatta ggcgagctag
    12541 gcagaagcgg atatggctat gatgtccctt ttcttatcga tgtattcaat aatatcctta
    12601 atactaaaga agaaaaacga atcgcattag taggatatgg aaatcttggc aaagcattga
    12661 aacacaacaa ttttagaaga aatgaaaatc taaatatcgt gtgcgtcttt gataatgatc
    12721 cagcactgat caatcgagta attgatggag aaatgatcta tccgattgat cgtttcgcgg
    12781 agatagccaa agcaaaaaat gtgacagtag caatctctac ggtaccaagt aaatattcac
    12841 aatctgctat tgatgaaatt gtcaaaggaa atgtaaccgc tatacttaat tttgcgcctg
    12901 acagagtaac tgtcccagct tatgtcaatg ttcaatacat tgatttgaca accgagttgc
    12961 agacgcttat ttactttgat gagaattact cagaagtttt ttcttaggaa aatttgagta
    13021 ggcttattga tcttgcgaga actcgtcgta attctttcaa aaatttttta gtactaaatg
    13081 aagtggtttt ttcacgacca cttgttgact aaaaaaaaaa accattgtag aatgaagcat
    13141 aacgctgaac aagaggagta actggcacat tcattcttag agagagaact atctgctgaa
    13201 aggttctcaa tgacaaccag tgaaggtagc ttgggagttt ctgtcttgaa tggagtagag
    13261 atagacgagt cgtgatcgtt aactcacttg agaggcaata atgattgatt attgcaattt
    13321 aggtggtacc gcgtaaatca tacgtcctag aatacgaaag tattttagga cgttttttag
    13381 tttaaaggag gaaaacagca tgacggaaga aaataaccta tcaacaaaat ataatccgca
    13441 agaagttgaa gctggacgtt atcagcattg gttagaacaa gatttgttta aaccgagcgg
    13501 agataaaaaa gcaaaacctt attcaatcgt aatcccgccc ccaaatgtta ctggaaaact
    13561 tcatttaggg catgcttggg atacgacctt gcaagatatg ctgattcgtc aaaagagaat
    13621 gcaaggatat gatactttat ggctgcctgg tatggaccat gcaggaatcg cgacacaagc
    13681 aaaagtagaa gcgaagctta gagagcaagg gatttctcgt tatgatctag gtcgtgaaaa
    13741 gttcatcgat caagtgtggg aatggaaaga agagtatgcg agccacatcc gcgaacagtg
    13801 ggctaaaatg ggcttatctt tagattacag tagggaacgt tttacattag atgatggatt
    13861 atctgaagca gtacgtaaag tttttgttac cttatacgaa aaaggtttga tttatcgtgg
    13921 tgaatatatc atcaactggg atcctcaagc acgaacagct ctatctgata tcgaagttat
    13981 tcataaagat atcgaaggcg ccttttatca tatgagctat gaactagcag atggatcagg
    14041 cgtagtagaa attgcgacaa cccgtccaga aacgatgttg ggagatacgg cgattgctgt
    14101 tcatccagaa gacgagcgtt atcaagcgct catcggcaaa aaagtgattc tacctttagt
    14161 caataaacaa atcccaatca ttgcagatga atatgtagat atggaattcg ggacaggtgt
    14221 agtaaaaatc actccagcac atgatccaaa cgactttgag gtaggtaatc gtcatgatct
    14281 tccacgcgta aatgttatgg atgatgatgg tacgatgaat gaactagcag gaaaatatgc
    14341 tggaatggaa cgttttgctg ctcgtaaagc aatcgtgcaa gatctgaaag aaatcggtcg
    14401 attgattaaa atcgatacga tgatccacag tgtgggtcat tccgagcgga caggtgtcgt
    14461 tgttgaacct cggctgtcta ctcaatggtt tgtaaaaatg gcgccgttag cgaaaaaagc
    14521 cattgataac caagaaacag atcaagcagt ggaattcttc cctccaagat tcaatcaaac
    14581 gtttttacgt tggatggaaa atgtccatga ttgggtaatc tcacgacaat tatggtgggg
    14641 acatcaaatt cctgcatggt atcacaaaga aacaggtgaa atgtatgtag ggatggaagc
    14701 accagcggat agtgaaaact gggtacaaga tcctgatgtt ttagacactt ggtttagttc
    14761 agctttgtgg cctttctcaa caatgggctg gccagatacg gaaagcgaag attataagcg
    14821 atacttccct actagcactt tagtaaccgg ttatgacatc attttcttct gggtaagcag
    14881 aatgattttc caaagcttgg aatttactgg cgaacgtcca tttgagaatg tcttgattca
    14941 tggattgatt cgtgacgaac aagggcggaa gatgagtaaa tcattaggta atggaatcga
    15001 tccgatggaa gtaatcgaaa agtatggagc agatgctctc cgctggttct tatcgaatgg
    15061 ttctgcacca ggacaagatg tccgcttcag ctatgaaaaa atggatgctt cttggaactt
    15121 tatcaacaaa atctggaatg cttcacgttt cgttatcatg aatatcgaag gaatgaccgt
    15181 agaagagatc gatttatctg gagaaaaatc agtggctgac cggtggatcc ttactcgttt
    15241 gaatgaaacg atcgaacgag taactgagct atttgatcgt tttgaatttg gtgaagcagg
    15301 tcgacaactg tataacttta tctgggatga tttttgtgac tggtacatcg aaatgagtaa
    15361 agaagtactt tatggagatg atgctgtttc aaaacaaacc acccgtagca tcttagtcca
    15421 tacacttgat cagatcctac gtttattgca tccaatcatg ccattcgtta cagaagaaat
    15481 atgggaacat attcctcatc agggaaattc tctagtagtg gcagaatatc ctgttgtacg
    15541 tccagagttt gatgatgaaa cagcttctaa agggatggaa gtattgaaag aattgattcg
    15601 agccgttcga aatattcgtt cagaagtgaa tacaccattg tctaaaccaa ttacgttgct
    15661 aattaaaaca aacgatgcta aaatcgatca atttttagtt gaaaatacaa gctatatcga
    15721 acgcttctgt aatcccgaag agttgacgat atcaagtgag atcactgcgc cagatctagc
    15781 gatgtcagct gttctgacag gtgcagaaat cttcttgccg ttagcaggat tgatcaatat
    15841 tgaagaagaa atcaaacgat tagaaaaaga actggaaaag tggacaagcg aagtaaaacg
    15901 tgtccaagga aaactttcta atgaacgttt tgtttctaac gcgccggaag aagtagtaga
    15961 ggcagagcgt gcaaaagaaa aagattattt agagaagcaa acggctgtca aagaacgaat
    16021 cgaaagtttg cgtactattc aataagaata gaaaaagaga gtgtgaaatc agctagctat
    16081 tactaaaagc tagctgattg aacatcgtta caggaaagag tttgagcctc actcttagct
    16141 tcgattcata aggagatgtg acataaattt tgtcgcatct cttttttagt ctactcttat
    16201 tatgtaggag aaggagggag gtggatcatg tatcaagagt caataaagta gttgataaaa
    16261 tcgttcctct ctctgtttct tttctctttg tcatactttt atttttctta tgtgttctat
    16321 ttgttataat aaaagagaaa tgggggaatt gttgatgacg attgaagaag caatagaatg
    16381 gatccatagt cgattaccat ttggttcacg tcctggcctt gaccgagtcg aagctttatt
    16441 agaagtggta gggcatccag agagaaaagt aaaaacgatc catatcgctg gaacaaacgg
    16501 aaaaggttct actgtagctt atttgagaag cctattagaa gaggctgggc tgacagtagg
    16561 tacatttact tcaccttata tcgaaacgtt caatgaacgg atcgcaatca atggcaaaag
    16621 cattccagac aatgatttga tccagcttgt aaaaaaatat cagccactga tcaaacaact
    16681 tgatcaattt gaagcagtag ctggtattac tgaattcgag acattaacag caatggcatt
    16741 tgattatttt ttgatgaaga aagtggacgt agcgattatc gaagttggct taggcggctt
    16801 attggattct accaatgtag ctgtaccaat gctgacggga ataacaacga ttggacttga
    16861 tcataccgaa atacttggag atacaattga agaaatcgct gcacaaaaag ctggaatcat
    16921 caaacaaggc gttccagtag taacaggaaa tattgcccca gaagctttta ctgtcatcca
    16981 acaaacagct aaagcaaaaa atgcaccgct ttatgtatac ggggaaaatt ataaaataaa
    17041 ctatctgcat cctgatgaga tgtggggaga agtatttgaa ttttttaatg aaataggaaa
    17101 gatccctcaa ttaaccactc cgcttttagg gcaacatcaa gctgaaaatg caggagtagc
    17161 catcgaattg tattttgttt actgtcaatt ggaaaagctg cctttccgag aaaaagatgt
    17221 tttgaaggga ttgaagaaat ctcgatggcc aggaagaatg gagcgtttga gtaacgagcc
    17281 attagttgtt ttagatggtg cccataatac gcatgcaatg aaccggcttg ttgagaattt
    17341 gaaaaaagaa ttcaaaggat atcaaatcaa cattttgttt tccgccttac gaactaaaaa
    17401 tgttagagaa atgctagaac gattgcagca agtaccaaat gtccatattt atttgacgac
    17461 ctttgaacat ccaaaagcca tcgaattaag tgaagtatca gatttagcaa gtgagagagt
    17521 atcaatcgtt tcattgtggc aattcggatt agcagatata ttggaaaaga tgacaaatga
    17581 agacgtatta gttgtgaccg gttcacttta tttcatttca gaagttcgcc atttattaat
    17641 acaattagga ggagatcatg aagtataatg cagtgatttt tgacatggat ggtttgctgt
    17701 tcgacacaga gttagtgtat tacgaagcca cacaagtagt agcagacaag atgggttttc
    17761 cttatgataa agacctgtat ttaaaattct taggtgtttc agatgaagaa gtatgggcga
    17821 attatcatat gattttctcg gaatttggca aaacaagtgt acaaagattc atagatgatt
    17881 cataccagga aacgcttgaa cgtttttcgc aaggagcggt acaaatgaag cccggtgtgt
    17941 tggaactcct ctctttttta gaagaacatc agattcccaa agttgtcgct tccagtaacc
    18001 aacgagcagt cattgaactt ttattgaaga agaacaatct gtttgaacga tttgagacga
    18061 ttgtttctgc agaaaatgtt caacgagcaa aaccagaccc agaaattttc ttgttagcta
    18121 atcagaagct aggtacagcg aagaaagaaa cattgatttt agaagattca caaaatggta
    18181 ttttagcagc ttctgcggct gagatcccgg tagtcatggt accagatctg cttccaccat
    18241 cccaagaatt gatcaaaaaa acagctgggg ttgtttcttc tttacatgaa atccctgcat
    18301 tgttaaaata aaaatccatc tcttttcgta tcttatttta gataagatag aaaggagatg
    18361 tttttttggg aaaacgattg atcaaagaag tacctactag ctctttacca agggaacgta
    18421 tggaaattta tggcgcggaa gctttatcgg atcaggagct tttggcaatc ttactgcgta
    18481 ccggtcaaca cccttatagt gtgatgtcga ttgctggaaa tctgttaaaa acgtttggag
    18541 gactggcctc tttacgacag gctactttgc atgagttaga agagattcga gggataggac
    18601 gcgtgaaagc aatcgaaatc aaagccttga tcgaattagg tcgacgaatt cagacggatc
    18661 atgaaagagc ggctccaccg gttcgtacca gctacgaatt ggcccagcaa ttgattctgg
    18721 aaatgaaaga tcacaaacaa gaacatttgg tttgtattta tttggacacg aagaatcaag
    18781 tgatcttaaa aaaaacagtg ttcatcggtt cgctgaatca gtcagtcgct catcctagag
    18841 aaattttcca ttatgctgta cgttattgtg cagcaaggat cgttttagcg cataatcatc
    18901 cttctggtaa tgttattcca tcgcagcagg atatgaattt taccaaaagg atacaaaagt
    18961 gtggagaaat gatggggatc actgtactgg accacttgat catcggacgc aaacgatatt
    19021 ttagtttgag agaagaagga atgatggaag agaagtaagt tgctttcttg caaaaaaaat
    19081 gaagcaagtg tacaattata ttgtaatttt gtttgggaat agaagttgaa acatctgttg
    19141 cacctctatc gtacacgagc aatgttacaa tttaaattag tgcttttggc acgaggagga
    19201 tattattatg gaaaacggaa cagtaaaatg gttcaacgct gaaaaaggat ttggatttat
    19261 ctcacgtgaa gatggaagcg acgtattcgt tcacttctca gctatccaag gtgacggatt
    19321 caaaacatta gaagaaggtc aagcagtgac tttcgacgtt gaagaatcag accgcggccc
    19381 acaagctgca aacgttgtaa aagcttaatt ttatctgtaa atcaaattga tggtagacat
    19441 caatttttac gagagaacaa agcgagtaac aaaaatacct gccacaagag acaatttctc
    19501 ttgtggcagg tatttttttg tatgaaaaag taaataaatt taagaggcta tgaaagagcc
    19561 accttgtatc aaggaataag aacaaacaaa aatggcttct catgtttttc atttgttttc
    19621 tcttatattc aggacaaggt gctgatttca taacctctta tttattcttc atctggtgtc
    19681 attaccattg gcaaaatcat tggatgtctt tctgtacgtt cgaataagaa aggctgaagc
    19741 gcgccagtca tcgcttcttt caatttatat tctgaacagt caggtccatt caaacattct
    19801 cttaaagcgt ggaataagat tcgctgagct tcattgatca tttctcctga ttctcgcatg
    19861 tagacaaatc cacgagagag aatatctgga ccagccaaga tttctttttt cttgatatcc
    19921 actgtcgcga cagctaatac aagaccttct tctgaaagca ggtgacggtc acgtaaaacg
    19981 acattaccaa tatcaccgat cccgctacca tcgatataca catctccagc cacaaaatgc
    20041 ccagcaggac gcgcagaatc gctagttaac gctaaaacat cgccattttc catgatgaag
    20101 cagttttctg caggaacacc tacatcttgt gctagagaag catgtacttt caacatgcgg
    20161 aattctccgt ggacaggaat aaaatatttt ggcttcatca aacgaagcat taatttttgt
    20221 tcttcttgtc caccgtgacc ggaagtatgg atgttattga tttttccgtg aatcacttct
    20281 gcaccagctt cagacagcaa attgatcaaa tgattgacac ttgttgtatt accaggaata
    20341 ggtgaacttg aaaagatcac tgtatcgtct ggctggattt ggatttgacg gtgagtacca
    20401 ttcgcgatgc ggctcaacgc ggccatcgct tctccttgag aacctgtaca taggatcatc
    20461 gtttcattgg caggcaagcg attgatttcg tgtgcatcta caaatgtgcc gtctggaact
    20521 ttgatatatc ctaaacgttg accgttgacg atggcatttt ccatgcttcg tccgaaaaca
    20581 gcgattttac gaccagttgc cacagcggca tctgctgctt gctgcaaacg gaagatgtta
    20641 gaagcaaagc tggcaaaaat gatacgtcct tcgatttttg aaaagatctt caaaatagaa
    20701 tgcccaatcg ttttttctga tttagtaaat gttggaatct cagcatttgt actatcagat
    20761 aaaaggcaca agactccttc ttccccgata cgagccattt tatgcaagtt tgctggttcg
    20821 ccaacaggag tgaaatcgaa tttgaagtct ccagtcgcta cgatatttcc agaaggtgtt
    20881 ttcaccacga tccctaatgc atctgggata ctatgggtcg ttctgaaaaa gctgacagaa
    20941 gtctttctaa aacggatgat cgtatcttca ttgatctcat ggagctctgc atctcgaagc
    21001 aagccatgct catctaattt gtttgtgatc aacgctaatg cgagaggacc agcatagata
    21061 ggaatatttg cttgtttcag caagtagggt attccgccga tgtggtcttc gtgcccgtga
    21121 gtaatcacca aggcttttac tttgtgtaag ttttgtatga tgtagctgta gtcgggaatg
    21181 acatagtcaa ttccaagtaa atcgtcttcc gggaatttga tcccggcatc aatcaaaatg
    21241 atttcatctt ggaattgtac cccatacgta tttttcccga tttcacctaa tccaccaata
    21301 gcaaagacgc ctgtctcgtt atttttgatg gaaagtttca tattaaaact ccactaatga
    21361 gaaatcagca ttttcttttt cgtactctag atgacttcct tctagaagtt gaacgaattc
    21421 aatattgtat ggggtatttt cttccacacg ttggcgagcg tctacatcgc tttttgcctc
    21481 aatgtaaaga gattttgttt cttcccgttt agggttgcgt acttttgttt cttgataata
    21541 aactttatag atcattgttt tgtctccttt atctgcgtaa agcagtgatt tagctagttg
    21601 atttttttag acaacacaaa acgaggggac aagccacctg gtttttcata tgctttgact
    21661 agaatactgg attcgagtca aagagacaag cctcgttttt gcttatctgt tcggatattt
    21721 tttcaaccgt accttctgta taaaaaatat acaacaatta attgttattc tagcataaaa
    21781 cagcaaataa gtatagaaat caactagatt gaaagaaaaa atcaatgttt atcatcccgc
    21841 tataatcata atgacttttt tatgagagaa gtgttctatt aataggctcg ttgtgctatc
    21901 atttttagta atgaaaatgt aacaaaagat taaaaggaga tgagaaagtg aaactaatgt
    21961 ggcattatac catgcgttat aagaaattct tgtttttcaa tttcatatgc gtatttggtt
    22021 ttattttgat tgaattagga cttcctacga ttttagcacg tatgatcgat gtaggaatcc
    22081 gcaatgatga ttttgattat gtgaagcaac aagggatatt tatgatcgtt attactgtaa
    22141 tcggtattat tttgaatatc ttgttaggtt attttggttc gaggattacg actaatatcg
    22201 tagcagatat tcgagatgat ttgttcgaaa agatccaaag ttattcgcat caggaatacg
    22261 aaaatctagg cgtatcttca ttgatcactc gtacaacaaa cgatgcttat cagatcatgt
    22321 tgttcctgca aaatatttta cgtatcggtt ttatggcacc aatgatgttc attgtcagtt
    22381 tgtacatggt catgcgtaca agtgtgacac tcagtttgta tgtagtaggt gcattacctt
    22441 tactattatt ggcagtcgta gcgattgcta aggtgtctga accgttatct aaaaagcaac
    22501 aaaaaaactt agataaaatc aacagtatct tgcgggaaaa tctttcagga ttgcgtgtga
    22561 ttcgtgcatt cgtcaatgaa aagtttgaag aaaaacgttt tgctgtagtc aatgagaatt
    22621 atgcttctag ttcaaaaagc ttattccgtt tgatggctgt tgcacaaccg ggtttttatt
    22681 tcttatttaa tatcgtaatg gtattgatca tctggagcgg ggcagtgcaa atcgatgcag
    22741 gcgagcttcg tgtaggagat ttgattgcgt ttatcgagta tatattccat gccttgttct
    22801 cattcatgtt atttgctagt gtgttcatga tgtatccaag agcagctgtt tcagctggac
    22861 gtatccaaga agccctagat gccaaacctt cgattgtaga agatccaaat ggtatatctg
    22921 atacaaaaac taaagggtat atcgaatttc aaaatgtaac atttgcttat ccaggccatt
    22981 cgcaagagcc agtgatacga aatgtcagtt ttacagcctc tccaggagag accgttgctt
    23041 ttattggaag taccggtagc ggaaaatcta cgttgatcca attgatccct cgcttttatg
    23101 atgtgagtga aggaaagatc ttgatcgatg gagtagacgt gagagattat cggctaagca
    23161 agttgcgaga taagattggg tttattccgc aaaaagcgct gctatttact ggaacgattg
    23221 cagataattt gcgatacggg aaagaagatg ctacgcaaga agaaatggaa cgtgcagctg
    23281 agattgctca agcttcagaa ttcatttctc gaaaaccaga tggatttaat gaacatttat
    23341 cagaaggtgg ttccaatttt tcaggtggac aaaaacaacg attggcaata gccagagcca
    23401 tcatacgccg tccggaaatc tatatttttg atgacagctt ttctgcatta gattatcaaa
    23461 cggatgcgaa gttacgtgct cgtctgaaaa aagaaacgac agaatctact gtattgatcg
    23521 tagcacaacg tgtgggaacg atcatgcatg cagataagat catcgtatta aatgaaggag
    23581 aagtcgtcgg tatggggacg catcgggagt tgttggaaaa atgcccgatt tattatgata
    23641 ttgccgcttc tcaattatca aaggaggaat tagcatgaaa aaaacctttt cttccttaaa
    23701 acgtttagct cgatatatca gaccgtatcg tgagactttt cttttagtga tcctatttac
    23761 agttctgaca gtggctttca acgtggcttt gccatatgtt acaggacttc ctactacaga
    23821 aatcagccgt aatattgcca atggcgaatc aatcaatttt tcttatatat tcaaatgtct
    23881 catttggatc acagttgttg gaatagggta ttgtatttcg caattacttt ctggtgtttt
    23941 gatgacaaat gtcgttcaaa gtgccatgca tgatttgaga agagacatag aagaaaaaat
    24001 caatcgtctt ccggtttcat atttcgataa aaaccagcaa ggaaatattt tgtctcgtgt
    24061 gacgaatgat gtagatgcag tcagcggtgc tttacaacaa gcttttattg gtatcgtaaa
    24121 tgcgatattg ggaattacgt tggctgcagc aatgatgttt tatatccagc cgatgatggc
    24181 gctgatctct atgatcatga ttccaacatc gatctggatc tcaaaacgag tgatcaatgc
    24241 ttcgcagaaa tattttcaaa gcatgcagaa ttctcttggt gagctaaacg gctacgtcca
    24301 agaaaatatg acaggtttta gtgtattgaa agtatatgga cgcgaaaaag aaacattgga
    24361 aggattcaaa aaagttaatc acagcttgaa atactttggg tttcgtgcag cattcatttc
    24421 tggcttgatg atgcctctag ttcaattaac tgcctatgct acttatattg gtatggctgt
    24481 tctaggaagc ttttatgtta ttactggggc gatcgttgtc ggtcaactac aagcattcat
    24541 ccaatatatt tggcaaatca gtcagccaat ggggaacgtg acacaattgt cttcagtttt
    24601 gcaaagtgca tcagcggcaa cgaaacgtgt attcgagatt ttagatgagc cagaagaaaa
    24661 agaaaacaaa gtagatgctt cactgccaga aacgatttta ggagatgtga cattcgatca
    24721 tgtcgatttt gcatatgatc cgaagaaacc attaatccaa gatttgaatt ttgaagtgaa
    24781 agctggtcaa accgtagctg tggtcggtcc gaccggtgcc ggcaagacga cattgatcaa
    24841 tctattgatg cgtttttatg acgtagacaa aggagcaata aggattgatg gaatcgacac
    24901 caaatcaatg agtcgcagtg atgtgcgttc gctatttggt atggtcttgc aagatgcatg
    24961 gctttatcaa ggaacgattg cagataatat ccgcttcgga aagcttgatg cgacagatta
    25021 tgaagtagtt gatgctgcga aaacagcaaa cgtagatcat tttatccgaa cgatgccaga
    25081 tggatatgat atggccatca attctgaggg agacaatgtg tctttaggac aaaaacagtt
    25141 gctgacgatt gcccgagcag tggtctccga tcctaaaatc ttgattttag atgaagcaac
    25201 aagttcagta gacacccgtt tagaagcgtt gattcaaaaa gcaatggatc gcgtgatgga
    25261 gggacggaca agtttcgtca tcgctcaccg tttatcgaca atccgtgatg cagatctgat
    25321 tctagtgatg gatcaaggtc agatcattga aaaaggaacg catgagagtt tattggcaca
    25381 aggtggattt tatgaaaaac tgtataacag ccaatttgct gaggaagcag aataagtcat
    25441 ataagaataa aacagtttaa aacttatttt ttgttctcta ttcttgataa tggtaaagta
    25501 aagttatcaa gaaaagtgag gacacggaga tggaacagtt tttaaatgaa aaaattactg
    25561 aagccaaaag agaagttgat cgtttaacgc acgtctgtca gacgaagcct tttgattcag
    25621 ctgatttttt tgaaaatgag tttcaaatcg aacgcttggc agcacaaata gaagtgtacg
    25681 aattaatttt aaaaaaagta atagaagaaa atatagatgt acaataaaaa caggtaaaac
    25741 gtcagttacc agatactgta aatagacatc tggcctgagc aggttttacc tgtttttttt
    25801 cttatgaaat aaatatatgc tatgatacct ttattcaata ggattagttt ctacaaaaaa
    25861 tgaaaggaga aaaataaata tggaacggtt tatagcatca aatgccacag tgattggtga
    25921 tgtgacattg tcagaagatg tgacgatctg gtatcaagct gttttacgcg gggacagtaa
    25981 ttggataaaa ataggacaaa gaacgaatat ccaagatggt acaatcatcc atgtcgatca
    26041 tgatgcacct gtagatattg cggagaatgt gacggtagga catcagtgca tgctacatgg
    26101 ctgtacaatc gaaaaagggg cgctgatcgg gatggggacc acgatattga atcatgcggt
    26161 tattggtgag aatagtttga ttggtgctgg atcattagta acagaaggaa aagttattcc
    26221 tcctaatgtc ttggcttttg gtcgcccagc taaagtgatc cgtcctttga caaaagaaga
    26281 aatacaaaaa aacaaagaaa acatccagca ttatgtcgag ataggtcgga tgcatgcgca
    26341 aggaaaattc aaggagcaaa gataggcagt agcatccata aaataaaaaa ggatggtcag
    26401 tttgagttga ccatcctttt ttatttggtt tagataagag agcttaaaaa agcttccttt
    26461 gaaacagatt aatttaatga agaactgttt tccatgactt catcgatcaa tccatatgct
    26521 tttgcttgtt cagctgtcat atagttgtca cgatctgtat ctttttcaat cacttcaagc
    26581 ggttgtccag tgcgttcagc taaaattttg tttaagcgtt cgcgtgtttg caaaatatgg
    26641 cgtgccgcaa tttcgatttc agttgcttgc ccttgagcgc cgccaagagg ttgatggatc
    26701 atgatctcag catttggtaa agcaaatcgt ttaccttttg taccagctgt cagcaagaag
    26761 cttcccattg aagcagccat acccataaca attgtttgga catctgcttt gacaaagttc
    26821 attgtgtcgt aaatagccat acctgctgta actgaaccac caggagaatt gatataaaga
    26881 tagatatctt tttcagaatc ttgagcgtct aagaaaagca attgggcgat gatcgaatta
    26941 gcaagatcat ctgttacttg gccgcttaac atgatgatac ggtctttcaa taaacgtgag
    27001 tagatatcgt aagctctttc acctcgtgaa gattgttcaa tgactgtagg aattaaattc
    27061 ataatagagt tcctccttga tttcgtttag aaatagtgta ccataattta gtttctaata
    27121 cctaaaatgt agtatacatt tttggtcaaa aaaggtcaaa taaaaaactt aggcaaatta
    27181 gtcgcataaa cccgctttat ggtatgataa gcagagaaac aaaacaagga ggaacaacag
    27241 attgatagtt ggtattactg gccttatcgg agtgctgaca ggtgctgtag ttgtctatat
    27301 cggcatgata ctgcaaatgc gtcacttgga aaataaagaa cagcgtagac gtgaattgga
    27361 attgaaagtc aaagaaatcg agacgctgaa tcaattaaat aaaaagatca acgagatctt
    27421 gcaaaaacgg acaacgctga tggaagaata tgtcagcttt gatgcatttg atgattgtta
    27481 tatcacgatt gacgattttg cgtatctcca atcattttca gcgcaaaata gtttttatct
    27541 gccaaattat attttagacg agctatttaa gaatatctcc catcgaaaag tgattttatc
    27601 tccagatgaa acaatgaaga ttggtggata tgcttataaa ggcggacgcg tgattttaga
    27661 gaattttacg gatagtctga ctgaaatgat caatgaaaaa aaagctcagt tgaagactat
    27721 gacgcgccag ccgattggtt tcttctcgaa agatgatgtt tggagctgat attttgaagc
    27781 attgccgttg cacatgagag cgtggtaatg ctttcttttt ttcttaatga tacaatagaa
    27841 ctgaacggag tgaagaaaga tgttacaaat ctatgcccat cgcggaagca gcggcaccca
    27901 cccagaaaat acgcttcctg catttgcaga agctgtacga gtaggtgcag atggtatcga
    27961 actagatgtc catctaagca aagatggtta tttgatcgtt atgcacgacg aagaagtgga
    28021 ccggacgact aacggtaaag ggctgattcg agaaaaaaca ttggaagaac tcaaaaaatt
    28081 gaatgcaggg ggcaaattca gcaaagaatt tccagcagct aaagttcctg aattgagaga
    28141 agtgttagga ctgctcctcc aaaaaaatta ccgagggatg ctaatgattg aaattaaaac
    28201 tgatcagtat gaatatcccg gtatcgaaga aaaattagcc gaaacattaa aaagtagaga
    28261 ttggcctttt caacatgcat attgcagctt tcatttggat tctttggaaa aaatcgcatt
    28321 actggaaccg gagatacagc tggacttatt gatgagtact tctgataaaa agatccaact
    28381 agcagcagaa accccttata tagaaggagt acatccaaaa aatacttggt tgttcgaaca
    28441 tccagtccag gcagctgatt ttccaaaagc aattcgtgca tggacgatta acgatgaaga
    28501 agaaatggcc aaatgtcaag aactcaaaat agatggaata ataactgatt ttccggagaa
    28561 agctcttcgg tggaaacaat caacgaaaag taggtaaaat atggaaaaag tattagtgat
    28621 cgtcggtccg acagcagtcg gtaaaacagc gctaagtgtg gaactcgcac aactatttgg
    28681 aggagagatc atcagtggtg attcattgca aatctataaa aatctggata tcggtacagc
    28741 aaaaatcaaa gaagaagaga tgaataatgt tccgcatcat ttgattgatg tgatcgaacc
    28801 tactcaacgt tactcagccg ctgattttca gcattcaggt cgacaattga ttaccgagat
    28861 tgcgaaccga gggcacctac ctatcatagc tggtggtacg ggtctctata tccaatccct
    28921 tctatatgat tatcagttag gagcgacaga agaagcgaat cctgagatta gaaaaaagta
    28981 tgaaacgtta gctgaaacaa ttggttccca agcattatgg aatcagttga aagaaaaaga
    29041 cccggcagct gctgagaaaa tccactggaa caatcaacgc aaagtgataa gagctctgga
    29101 agttttagag acgacaggac atagtatcac ggcacctaaa gaagagccaa agcaattgta
    29161 tgattacctc atgattggat tagatacgaa gcgtagtatt ctttatgaac gaatcaatca
    29221 aagagtcgat ttgatgctag cagaaggttt agtagcagaa gcgcgtaagg tgtatgagct
    29281 tggagaagtc caggccagtc aaggtattgg atataaagaa tttttccctt attttgaagg
    29341 gaaagaaaca ttggaagaag caacagaaca agtcaaacta cattcgagaa gatacgcgaa
    29401 acgtcagttg acgtggtttc gtaaccgttt ggatgcacag tggtttgatc ttataagtga
    29461 gccaaatcaa aaaagtcaga ttgagcaaac aatcaaaaaa tggctggagg cggaataaaa
    29521 tggaagaaaa agtgatcatc gtaggggtag aaaccgaagc aaaccagcgt tacttttcag
    29581 agtcaatgga agagctagtt cagctgacga ataccgcatc aggagaagtc gtattcacaa
    29641 ttacacaaaa gagaccacaa gtggatcggc aaacgattat cggtaaaggg aaattacaag
    29701 aattagttca acaagcggat gcgcatgaag cggatttgat catctttaat catgagctaa
    29761 ctccgagaca gagccaactg attaccgatg ctgttggtct tccggtaatt gatcgcgtgc
    29821 agcttatctt agatattttt gcgatgcgtg ctcgttcgaa agaagggaag ctgcaggttg
    29881 aacttgctca gttagaatac ctgctgcctc gtttagtagg gcaagggaaa acattatctc
    29941 gtcttggcgg tgggatcgga acaagagggc caggtgaaac aaagttagaa acagaccgcc
    30001 gacatatacg gaataaaatt tttgctgtta agaaagaatt gaaagaagta gaagctcatc
    30061 gagagcgcaa tcgccaaaaa agaaaaaata gcgagatttt tcagattgga cttattggct
    30121 acacgaatgc cgggaagtca actatcttga atctattgac acaagcggat acttattcga
    30181 aagatcaatt gtttgcaacg ttagatccat tgactaagag atggcgtttt gctgaaggat
    30241 ttgagattac tgtaacggat accgtcgggt tcatccaaga cctgcctacg caactgatcg
    30301 atgctttcca ttctacatta gaagaaagtc aaaatatgga tcttttgcta catgtagtcg
    30361 atgctagttc tccagatcgt attttacagg agcagactgt cttaaaattg atggatgaac
    30421 tgaatatgaa agaaatgccg atactgactg tttacaataa ggcagaccag atcgacccag
    30481 cgatgttcac gcctacgcta ttcccaaatg tattgatttc tactcagacg aaagaaggta
    30541 agatggcgtt gatcgaagca atcaaacgtc agctgatgga actaatgacc ccttatacac
    30601 tttctgtgcc aagcaacgaa ggacagaaat taagcgagtt gagaagacaa acaatggttt
    30661 tggacgaagc gtacatggaa gaaacaaacg aatatgaagt taaagggttt gcaaaaacca
    30721 attcaaaatg gttaagaaaa aaccaataaa attttatttt tttaa
//
LOCUS       DACCVZ010000027        29182 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.027, whole genome shotgun sequence.
ACCESSION   DACCVZ010000027 DACCVZ010000000
VERSION     DACCVZ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29182
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.027"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..124)
                     /locus_tag="IVW63_001253"
     CDS             complement(<1..124)
                     /locus_tag="IVW63_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein"
                     /protein_id="HAP7859536.1"
                     /translation="MLLLIGLILLIIGITKLSKANTIKKEAYELEQKNDEKLNKL"
     gene            complement(215..667)
                     /locus_tag="IVW63_001254"
     CDS             complement(215..667)
                     /locus_tag="IVW63_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP7859537.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(680..1090)
                     /locus_tag="IVW63_001255"
     CDS             complement(680..1090)
                     /locus_tag="IVW63_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7859538.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            1365..1577
                     /locus_tag="IVW63_001256"
     CDS             1365..1577
                     /locus_tag="IVW63_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7859539.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            1580..1792
                     /locus_tag="IVW63_001257"
     CDS             1580..1792
                     /locus_tag="IVW63_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859540.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            complement(2084..2308)
                     /locus_tag="IVW63_001258"
     CDS             complement(2084..2308)
                     /locus_tag="IVW63_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004401476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAP7859541.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            2386..2574
                     /locus_tag="IVW63_001259"
     CDS             2386..2574
                     /locus_tag="IVW63_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859542.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2900..3235
                     /locus_tag="IVW63_001260"
     CDS             2900..3235
                     /locus_tag="IVW63_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859543.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            3468..4409
                     /locus_tag="IVW63_001261"
     CDS             3468..4409
                     /locus_tag="IVW63_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAP7859544.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            4411..5301
                     /locus_tag="IVW63_001262"
     CDS             4411..5301
                     /locus_tag="IVW63_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HAP7859545.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            5344..6144
                     /locus_tag="IVW63_001263"
     CDS             5344..6144
                     /locus_tag="IVW63_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAP7859546.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            6159..7010
                     /locus_tag="IVW63_001264"
     CDS             6159..7010
                     /locus_tag="IVW63_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP7859547.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            7211..7672
                     /locus_tag="IVW63_001265"
     CDS             7211..7672
                     /locus_tag="IVW63_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010781228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7859548.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            7698..8150
                     /locus_tag="IVW63_001266"
     CDS             7698..8150
                     /locus_tag="IVW63_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859549.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            8256..8450
                     /locus_tag="IVW63_001267"
     CDS             8256..8450
                     /locus_tag="IVW63_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859550.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            8481..8774
                     /locus_tag="IVW63_001268"
     CDS             8481..8774
                     /locus_tag="IVW63_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859551.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            8804..9244
                     /locus_tag="IVW63_001269"
     CDS             8804..9244
                     /locus_tag="IVW63_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7859552.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            9319..9786
                     /locus_tag="IVW63_001270"
     CDS             9319..9786
                     /locus_tag="IVW63_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HAP7859553.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            10533..10763
                     /locus_tag="IVW63_001271"
     CDS             10533..10763
                     /locus_tag="IVW63_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859554.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            10922..11755
                     /locus_tag="IVW63_001272"
     CDS             10922..11755
                     /locus_tag="IVW63_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HAP7859555.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11748..13163
                     /locus_tag="IVW63_001273"
     CDS             11748..13163
                     /locus_tag="IVW63_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP7859556.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            13175..14704
                     /locus_tag="IVW63_001274"
     CDS             13175..14704
                     /locus_tag="IVW63_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP7859557.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            14796..15674
                     /locus_tag="IVW63_001275"
     CDS             14796..15674
                     /locus_tag="IVW63_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAP7859558.1"
                     /translation="MMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15676..15993
                     /locus_tag="IVW63_001276"
     CDS             15676..15993
                     /locus_tag="IVW63_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859559.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            16042..16743
                     /locus_tag="IVW63_001277"
     CDS             16042..16743
                     /locus_tag="IVW63_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HAP7859560.1"
                     /translation="MVEWWGATIKTQSNAGRENESWGERRMSMKHKSLMPMNLQYFAE
                     GDDQKFSFDDFKSFVESNEEAQKFIQSQSQSVADKQLEAWKQNNLDKIKQDTIKEYEE
                     SKKNKSPEQIQLEKLQAEFEAEKALRVTSDNKAFVAEQIAGLELDGELKESISQFMLN
                     NLVSSDTDFTKNAVEGFTSVLNAINEKHADALKELQMKSAFGGTQQSNNQVQQNNETL
                     TNPEEQLGQILQQFN"
     gene            16758..17648
                     /locus_tag="IVW63_001278"
     CDS             16758..17648
                     /locus_tag="IVW63_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HAP7859561.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17671..17886
                     /locus_tag="IVW63_001279"
     CDS             17671..17886
                     /locus_tag="IVW63_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859562.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            17898..18239
                     /locus_tag="IVW63_001280"
     CDS             17898..18239
                     /locus_tag="IVW63_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859563.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            18239..18610
                     /locus_tag="IVW63_001281"
     CDS             18239..18610
                     /locus_tag="IVW63_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859564.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            18603..18998
                     /locus_tag="IVW63_001282"
     CDS             18603..18998
                     /locus_tag="IVW63_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAP7859565.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            19000..19377
                     /locus_tag="IVW63_001283"
     CDS             19000..19377
                     /locus_tag="IVW63_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859566.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            19378..19986
                     /locus_tag="IVW63_001284"
     CDS             19378..19986
                     /locus_tag="IVW63_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP7859567.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            19986..20327
                     /locus_tag="IVW63_001285"
     CDS             19986..20327
                     /locus_tag="IVW63_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859568.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            20569..23358
                     /locus_tag="IVW63_001286"
     CDS             20569..23358
                     /locus_tag="IVW63_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HAP7859569.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AFFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            23348..24088
                     /locus_tag="IVW63_001287"
     CDS             23348..24088
                     /locus_tag="IVW63_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP7859570.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            24085..26847
                     /locus_tag="IVW63_001288"
     CDS             24085..26847
                     /locus_tag="IVW63_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAP7859571.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYE
                     RPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYS
                     GYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIIN
                     WARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISS
                     IVIPPK"
     gene            26860..27768
                     /locus_tag="IVW63_001289"
     CDS             26860..27768
                     /locus_tag="IVW63_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAP7859572.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            27768..28388
                     /locus_tag="IVW63_001290"
     CDS             27768..28388
                     /locus_tag="IVW63_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859573.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            28392..28841
                     /locus_tag="IVW63_001291"
     CDS             28392..28841
                     /locus_tag="IVW63_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859574.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKAKLDGLANITFEKVGTV"
     gene            28841..>29182
                     /locus_tag="IVW63_001292"
     CDS             28841..>29182
                     /locus_tag="IVW63_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859575.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYR"
BASE COUNT        10471 a         4205 c         6033 g         8473 t
ORIGIN      
        1 gtaatttatt tagtttttca tcattttttt gttctaattc ataagcttct ttttttattg
       61 tgttagcttt cgacagttta gtgattccta taattaataa aataagtcca atcaataata
      121 acattcaaaa ctcctcattt ctttgatata attattgtag agtttactca gaaatgagga
      181 aagagtccat gtgaaagcat gggctttttt atttttaatg ttgtaatact aaatgttcaa
      241 gattatgagg aagccctaaa tattcaataa tttggaactg actcatatca gataaatctt
      301 gttcatctat tgttctagtt aacatttcaa ttgcaaacat attagcttca gcttctatac
      361 cataaatcat acaactaagg ttgtttgctc taaaagctgc tgtgcaaata cctttatgga
      421 gtctaacgtg ggctatttca tgccataata caaatctttt catagaaggt gataggtttt
      481 gattaattaa tatcacataa catcttttat tgtgtatcgt ttgtcctaat gttttattcc
      541 ctaaatcagt ttcaattaaa tctatatcag aatatttgat tattttatat ggattaatcg
      601 catcagatcc aaactctaca aataattttt ctatttcttc taatatccag tatttgttta
      661 aatgcatacc aaagcccacc tattgacgat attttttagg agtgaatttt ttctttgctt
      721 taactttggt taaggcaagt gcaagttgaa tggcatcgta taatttttcc ttatcttcat
      781 cgtctaaagg ttcaccataa taatttgttt cagcatctga attcaagcct tcaagtaatt
      841 tttcagcttg taaagcaata tcttgtttat ctttttctgt taaatcataa taatggcgtt
      901 tatcagtacg tcctaaaaga taatcagttg atacattaaa gtaatctgca actttttgta
      961 ttttatctcc agatggagta cttttattcc atctagacat gcttccattt ccgaaattta
     1021 actttctttc aagttctgcc aacgtcattg aacgttcttt taataagatt tttatacggt
     1081 ctaatagcat aggatatgca ttcctttcaa aataccgaca aaaaaagtat ttttctgcaa
     1141 attatctatt tacaaataga gaatttgcag ttatactagt tttgtaagca agatatttac
     1201 ggcatacaaa gactaaaagc aataaactaa tagtctcccc agacatcagt aagctcgctt
     1261 tttgtgcgct gtattttgta tgcttacata atagcatatt tgcagttttt gtcaaactta
     1321 ttagacaaaa atattagaaa atattcgata agggggtatg aagcatgact ttaaaacagc
     1381 aagtattaat tgctttagta aagaaaggtt ggagtcaaag agagttagct cgacgaatgg
     1441 gtatatcaat tacttattta cgagatatct tcatcgaaaa aagaaaacct aaggaacgtt
     1501 taaaacaaat cgaagaactt ttggatatca agttagaagt agattctaat gatcagccat
     1561 cagaacagga ggcgtaaaaa tggtacaacg tttgagcaaa gcggagttta aagagaaata
     1621 taagtattct gaaagtactt atcaaagaag aatgaaggaa tttaaaaaat cacgttttag
     1681 tgaggggtat aacgcagtta cttccaaaga aataacaatt gatgtcgatt tatatgaaca
     1741 gtttagaaca tggcgttcta aaaatcgatt tagagttaga gctgtttgtt aatagctaaa
     1801 aaatctaaat tcaccacttc tgaaaagagg agttgctgct ctcctttcaa gtttgccaaa
     1861 gtccacgttt tttcattttg gcaactcctc ttcttggagg tggtgacggc gagagacgaa
     1921 ggagggatga catgaaggaa gaatcaaaaa tagggatttt gaatgagaac aattacacaa
     1981 gattaattat tgaaacagaa gaagggaaaa aagtagcaga agttacattg accgatgcaa
     2041 ctcctgctga cggttatcgt attcgattaa ctcctaaata tgattaacct tttggtgggt
     2101 gtggatcgtt tccgtgacta tcacggcttt gaatttttcc atctctgcca tgaataaata
     2161 gctcagatcc ttgattttta gaaatctctc tagcgatttt tactgcttct gattttgtat
     2221 tagtatgtgc agtcgcttta gaatttccag cacctttgac attccaacca ccattggaat
     2281 taggtacaac atgttgattt tttcccatag ttttcacctc catttctata gaaatatttt
     2341 atcaaataga aatggagaaa ttcaataaac gaaaggagaa gtgatatggc atataccttg
     2401 caacaagaac atcaaattct cggtttgatt aaacaacgca ggaaacaatt acaagatgac
     2461 cgtgcagcgc ttagaaaagc cgatgagcta tcagataggc aagctgaact aattgcttct
     2521 gaacttgagg atttgagaat gctagaaata aaaaataggg agattagatt atgaagaaga
     2581 cagacacact ttttatagga ttcattttgg ggttattagt gattgtagcg caccaaagta
     2641 ttatcggggg aagcttgttc gcagcattga tggttttaat caatctgctt gattcaaaag
     2701 aaaggagcaa ctatggcacg agaagaagcg ctaaaaatcg gtaaagtgat tgctgataat
     2761 cggtggggaa atagccgccc tattatttta agcaagcaac atatcgaaaa gcaaaaagca
     2821 tggcaacaaa taaaaaagtg actctgccag ccagcaaaga gtcacataca aatttataaa
     2881 actaggagaa ttatatcaca tgaataagaa aattgaaaat cttatcgaag aattgaaacg
     2941 tgaatgccaa aagcaaggtg tttctattat ttgtacagcc caaaaagaag gggaacttaa
     3001 aagtctcgtt tatggtgaga caacagaaat tttactttgt cttgctatgc aagaagaaca
     3061 tttagatgaa aatctcccat tgtcagcaca tattatgcgt agaattgctg tggatgctta
     3121 cgaacaagcg aaaaatgaag aagaaaatca accttcaaat catacttttg ttattaataa
     3181 caaggaagat ttagctgatg tgatgactcg tattctcaag ggggaatttc aatgatgaat
     3241 gaaaaaacaa ttgatctact cattatttta tttttcacgt tagtgattgt agcgaaaagt
     3301 tatgtaatct ttggcttgtt attcgcaatt accatgcttg tgctttgcgt gttagcaagc
     3361 agaaaagagg ttaaacatga acgagttagc aaatcttgac aactatttaa ctgatcctga
     3421 ttatgctaaa ccaccatatg aagcaccaat tgatgaggag gatgaagatg agtaaatcta
     3481 ccttagaaat gagccatcaa gaatggcttg aagaccgtaa gaaaggcatc ggaggttcgg
     3541 atgttggaac aattttagga ttgaataaat ggaaatctcc ttatcaacta tggctagaaa
     3601 aaacaggaca agtagtactt gaagaatcag gaagtgagcc cgcttattgg ggtaatgttt
     3661 tagaagaagt ggttgctaaa gagtttcagg aacgtacagg caaaaaagta cgcagaagaa
     3721 accaagtatt tgaacatcca ttacatccat ttttaagagc aaatattgat cgggaagtag
     3781 tgggagaaaa tgccattctg gaatgcaaaa cagccaatca atttctcggt aaagaatggg
     3841 aaggcgaaga ggtaccgctt agctatctct gtcaagttca acattacatg aacgttctaa
     3901 acaaagacta ttgttacatc gctgtcttaa tcggtggtca aaaatttatc tggaagcgga
     3961 ttgaacgaga tcaagagctg atcgatacaa tcactgaaca attagtagag ttttgggaaa
     4021 caaacgttct tggaggtatc gagccaatta ttgatggtag tcaagcgaca gctgatttct
     4081 tgaaagagaa gtatgcagat gttgaagacg ttcaaacgac gttaccaatt catttcgatg
     4141 aactagttga acagaaaaac gaactcaaac ggactaagaa agaaattgaa tcagctatcc
     4201 gtcaagtaga caacgagatt atcagcgagc taggtaaacg tgaagccagt atcggtatca
     4261 ctcaaaaaaa catcatcagt tggaaatttg tccgtacgag acgtatgaac tcgaagaaac
     4321 tagcagagaa atatccagat gtcgcaaatg atgaagagat ttataacgtt actgaatcaa
     4381 gaaggctaac cgaaagggag atcaaataat atggcaacaa atgaatcgtt aaaaaatcaa
     4441 ttggcagcaa agccacagaa acaagttgca ccaggtcaat taggacttaa agctttgatg
     4501 aatacaccaa caatgagaaa gaagttcgaa gaggtgcttc atgacaatgc taatgctttt
     4561 atgtcgaatg ttatgactct tgtatctaat gacagttatc ttgcagatag tgaaccgatg
     4621 tctatcatga gtggtgcgtt aactgctgca acattaaatc ttgggctaga taagaattta
     4681 ggttatgcat atttagttcc attcaatagt aaaaacaagc aaacaggaaa atgggaaaag
     4741 aaagctcaat tcatgcttgg ctataaagga tatatccaat tagcccaacg atcaggtaaa
     4801 tacaaagcat taaatgtgat cgaagtttac gaaggagaac taaaaagctg gaaccgactg
     4861 acagaagagt ttgagtttga tccaaatggt agaacgtctg atgaagtcat tggatatgtt
     4921 ggctatttcg agttactgaa tggattcaaa aaaactgtct attggaccaa acaagaaatc
     4981 gaagctcatc ggattgctaa caataaagat cgcgataaga caaagttaag tggtgtgtgg
     5041 gcatctgatt acaatgcaat ggcacgaaaa actgttttga gaaatcttct ttctaaatgg
     5101 ggaatcttgt ccatcgaaat gcaagaagcc accacatcgg atgagagagt ccaaagggtt
     5161 caagaagacg gcagcattat tgctgaaaca gaagttgaag aagatattcc tgaaagaaaa
     5221 gaagcagagg ttatatctga agaaaatgaa gatgtacaaa ctggattatt tgatgcatct
     5281 aatccgccgt taaacaaata atgagggagc tttctccctt gcttttctag aggagaaata
     5341 cgaatgaaca caggatatgt caaattacat cgaaaagtga tgaattcatt cgtttggacc
     5401 aatccttata tgtataaatt atggaacttg tgtttgatga aagcgagtca tgagaatcgc
     5461 aagatacttt ttaatggaaa agagatacaa gtgaacagcg gagaattcgt cacagggcgc
     5521 gatgctatca catctgagat gaacgaaggc gtgaaacgtg aacatcaagt gaacagcggt
     5581 tctgtatgga gatggctaaa acaatttgaa aaaaacggaa tgttgaacat caaatcaact
     5641 acgaaataca gcgttatatc aataaaaaac tggtctttgt accaaagcag tgaacaacaa
     5701 atgaacatca aacgcacaac aagtgaacaa caagtgcaca caaacaagaa tgaaaagaat
     5761 tataagaatg aaaagaataa taaaacatca tcgtcgcaac cacgcaaaaa gcgtgtttac
     5821 gacaccgact cagtttacta cattctcgcg gaggagttat tcaaacagat ttgtcagaat
     5881 caggaaatca aaaagccgaa tctgcaaagt tgggcagatg acattcggaa aatgatcgag
     5941 atcgacaagc ggaccgaaaa ccaggtacgg ggaatgattg aatggagtca gcacaatgtg
     6001 ttttgggcat cgaatatttt atctgctaaa aaattgcgag aaaaatacga cacaatggca
     6061 gcgcaagcaa atcgtgatta taaaacaaaa caaactaaaa cgcttgaata cgagaaattt
     6121 agcacagatg agttgcctat ttgagaggag gcgtaggcat ggaaactgtt ggggaaatca
     6181 tggaaaagct gatacagaaa gtgcttgtcc aacgtggcga atgtcctgaa tgcggacagc
     6241 ctttgtatgg atggcgtacg aagaaccctg atggctcaga acgttgtaag ccaacctgta
     6301 tgcaatgtgg gtataaagca ttgcgagttc aggaagactt acaaacagaa cgaatttaca
     6361 acgagagcct gaaagcaaga gcaatcaatt ttttcaaagg tggttctgtt gtgcctaatc
     6421 aagcgttgtt tgattgcaca ttgcagaatt atcaaattgt cgatcaagaa acaagacaag
     6481 cggttgaagt aaccaaacgc tttgttaatt cagtcttgtt aggaaatcca agtcaccttg
     6541 ttttaactgg aaaacaagga acaggtaaaa gtcacctagc gatggcagcg gcttgggaag
     6601 tcttgaagcg atcaaactac gataaaaaaa tcttatttat cgggttacag gaaatgctgg
     6661 atcaaatcaa attttcgtac aacaatcctg aactcagaaa aacgattgag ggatcgttga
     6721 ttgcagatat caaaacagcg gatttagtca tcattgatga tatcggttca gaactaggaa
     6781 aagatgcatc agatagtcga gcgtttggca taaacacgct aaattcgttc ttggatgcac
     6841 gacagaacct agcaacgatt atcacaacga acttgcttgg tgaagaactg aaaaaagctt
     6901 acggtacgag aacaatatca agaatgtttg tcaactctga tggatttacg atggtatttt
     6961 ctcaaacagc agacaagcgc ataaaaccag tcaaaggagc gatcgcatga atttgactaa
     7021 acaagaaaaa agaatctgtc gtcagataat gttgcaaatt ataggtgatc gtgacatgga
     7081 cgaattatct caacaagaga gtcgaatggt tcggaagata agtaagctaa ttatttatcg
     7141 ggatacagaa agatttctca ctgttttagg taacgtctac gagaatccag agttattgga
     7201 ggtagagtaa ttgccaaaaa tattagatgc atgttgcggt agtagattgt tctggtttga
     7261 taagaacaat tctgacgtaa catttatgga ttgtcgtcag cagtatgaag aattatcaac
     7321 aggtcatgtg atcaatgttg atccagatgt ggtcgcagac tttcgcgata tgccttttga
     7381 agatgatgtg ttcgatatgg ttgtatttga cccgccacac ttaagacatg tcggcgaaaa
     7441 ctcatggctt gccaaaaaat atggaaaatt agacgaactt tggccagaag acatcaggca
     7501 aggttttgca gagtgtatgc gagttttacg accttcagga acattaattt ttaagtggaa
     7561 cgaggaacag ataccacttt ctgatgtgtt agaggctatt ggagaacagc cattgtttgg
     7621 taataaacga agcaaaacac attggcttgt gtttatgaaa aaattcagct aacggaggaa
     7681 acaaaggagg aaaagtaatg aagattgtat taaataaatg ttttggtggc tttgggttga
     7741 gccatgaagc aaaaatggaa atttttaaaa gaaaaaatat tgaagtattc ccatacatca
     7801 ataactttag ctatgactca gatgatgaat acacgagata cacaggccaa aagctaggtt
     7861 cgatggattt tatctactat ttcaaaaaag acccgaaaat cgacaaagtt acaggaattt
     7921 atagcgaaat tgaccgactg tacggaattg ctgatgattc cagtttttca agtgattcaa
     7981 acagaggtga taaggacctc gttgctgttg tcgaaaaact aggaagtgag gccagtggac
     8041 catatgcaag tcttaaagtc gttgatatac ccgatggggc tgagtgggaa ataagtgatt
     8101 atgacggcgt tgaaactgca cattatggtt ttcaaacagg tagtatttag tccactaatg
     8161 acaactaaag aggaggcaga aggatgagtg aagatgaata ctttgaacag tagtctatta
     8221 acgacagaga tttttaactg gaaaggggtg tagtcatgga cgcatcggaa gtagtaaata
     8281 aaattaatag tctcaaagag gttttcggag acgtcgaagt agtgataaac gcacaaggct
     8341 atgacaacga attttttaag cagattaccg acattagcat tcagcaagga atggaagacg
     8401 aagacggaaa ctttatcgat gaagtagcca ttttagtgac ttgcgagtaa gtaattgaca
     8461 gctaaagagg aggaagcgga atgaaactaa aagacggatt ttactccagc ggccacggca
     8521 tcggcggttt aatgctagat atgccgacaa agaatcctaa aacacgtaag aaaccaaaat
     8581 tcaaagtcgg tgacatggtt cgctgcgaag cagaaggatt catctatcca tttcgtggat
     8641 atgtagaaca cgtctataat cactcagcaa tcattcgcat tgaaaacacg atggaatgtg
     8701 ataagtggtt agcgaaaagc aaagagaatt tagcagtggt gagattggtg gacatggaag
     8761 ttataaaatc ttaattttgc ttttttacaa ctatcctaca acaatgagcg ttattccaca
     8821 actggaagga gaagaggcaa ttgtgaacat tttagagaat atagatatta agcaaacaag
     8881 gaaaaatgct agacgattac taaaaagata cagaaattta gaacgtttgg tcggaccagt
     8941 gaaaatagac ttttccgtga tgactgttac caaaaatttg aaattcacaa ttgacagtca
     9001 aaacgaagaa atcattgaag cgataagtac tcgagattcg gttatcgaag cattaacacg
     9061 gctaagtaga atccatttcc aggtacttta ttatagttat tgttttccta ataagatgtc
     9121 aatgtatcaa ataggagaaa aattaggata ttccgataga actatcgaga gaatgaaggc
     9181 agtagctttg gttgaatttg ctgaggcgta taaatcagga gaactcattt cacgtacaaa
     9241 ataaaaaaag tcggattcct ccgactatga ataatatttc cgacataagt attatatcat
     9301 aattggggga atcagaggat ggtacttttc gatgtaaaga aatatgagac accaagcgcg
     9361 aaagatgttg atatggaacg cacaaaacat aatgtcgctg tgtttctttc agcatatcta
     9421 tcagctagat gtagagtagg gcaacatcga gaaccaaaag tgacagcatc ttattccttg
     9481 gttccacctt ctacagctga tcatatattt gaagcagaaa gaatgctgat cgataaagaa
     9541 gaagcacagg aagaatttga gtatctgcat aaattgtttg ttcgaggcta ttcagcgata
     9601 cagcatccgc ataagcctga tgtgactgaa aggcgcaaga agatattcta tgatcgttat
     9661 atcaatggtc tgcccattta tgtaactgct caaaggaata atactagcga agaatcggtt
     9721 aaagtagaat caaacagaat tatcatccaa tttgcttcat cgttagaact ggttgctttc
     9781 aagtagccag tttttacact ttttataccc ttttattacc aatttggttt ccattttata
     9841 ccttttttat accaatcact tacctattca acgttgtatt atgatagtgt cgaaaaatta
     9901 ggaaacagga tcgacaaaat aaaatgtaag ggaggaaatc tccctcatcg tttaattaag
     9961 cttcgatagg cagcaacgga aatattaaga ataaggatgt gaatttcaac tccttctaaa
    10021 ttgttcttat tatctatcat ccgttgctgt ctattgtttt tttaattatt cacacgataa
    10081 ctaaaggtaa gtgaagagaa atgattccat taataatttc aatttttgcg ctttgtctta
    10141 atgtatatat gattggattt aaaaatgggc aaaataaaaa atagtagcag ccaagaataa
    10201 ttttatagtg tcactgtggc ggaaagggta gacgctaagc atgtgtgcta ggtcaatgct
    10261 tcggcaacca tgcaaggttc gattccttgc cagtgacttt ggcaaccgag gcatcggcgg
    10321 tttaaaaata taggggtgcg caatttcgta cgcgttttgt gcatcgtgta ggttgctatt
    10381 acataactgg ttaggttaga ttgagatttg ggattcggta caaatgaatc gtcaaatgtc
    10441 tcaagcacag gatcggaaac gtccctgcct gtgcattaca tattagatca ctctttgagt
    10501 ggtctttttc tttacataaa ggaggctaca taatgagaaa ctactggtat gtatcgctaa
    10561 ctaatgaata tcctcgaacc attgatgatt gttcagtgcg tgttgtgcgt tctgtacaaa
    10621 tcaaagggaa gtactctatt gtcgaaatgg ggagagaagc agaaccatgt gagattgatg
    10681 cgtgcaagct cgtttattgc ggtcatggtt tctatgatga accaaacatt caaaataata
    10741 ttaacaagaa tttgagggat tagaatgcaa gaaatggctt aaaaatctcc aatcaggaca
    10801 aatcaagtta gacaaagttt ccgatttaaa gatattgatt gaagctgatt taatgctaaa
    10861 agatattgaa aattagaaaa caaaactcaa cctaaacaga atgtgaggtg gtgtgtattg
    10921 aatggcaaga caacgtgatc caagacgtga tgaagccaaa agaatttggt tagaatccaa
    10981 cggagaaaag cagttaaagg aaattgcatc tgaattaaat gtttcagatt ctcaggttag
    11041 aaaatggaaa tcgcaagaca aatggagcgc tgaattgatt agtaacgtta ccaatggcaa
    11101 aagtaacgtt actaatcaag gtggcgctcc tattggtaat caaaatgcta aaggtaacaa
    11161 aggaaatagc cgagcttctc cgccagtggg taataaaaac gctttgaaaa caggtgagta
    11221 tgaaacaata ttttttgaca cgttaaccga taatgagaag gacatctatt ctagtttgaa
    11281 tgatgatcct tcttttgctt tgtccgaaga aatacgactt cttaaaataa gacaacttcg
    11341 aatgatgaaa agaatccaac aagctgaagc tggactaaat gatgaagaag tcgaacgatt
    11401 gcagcagcta agaaagatta aaactccgat tgaaaaaaat ggtaaaaagc tagaaatcaa
    11461 gcgtgaggtt atgcaagatg tgcagattag cagaaaaaaa catcgcaaaa ttgatgatat
    11521 tctttcaatt gaagattcat tgactcggat tagcaaccag ttagctaaag ccatcaagca
    11581 aatgaatgaa ctttatatga atgaatacag aactgattta attaaagctc agactgataa
    11641 gatccaagct gagacaaatg aaattggcgg aaataattca ggtgaagaaa tagaagaatg
    11701 gaaacaggca gttttaaatg ccgcaaacaa acgggcggtg aaagaaaatg aataatgaat
    11761 ttattccttt tgctgatatt ggttctgcca ttgattatta ctatgataaa ccagtagctt
    11821 tttgccaaga tattttgcat ttgaatcctg atgaatggca agaaaatgtt ttaaatgatt
    11881 tagctgaatt ttcaaaggtt tctgttcgtt ctggtcaagg agttggaaaa acagcattag
    11941 aagcaggagc aatactttgg ttcttaacgt gtcgacccta cgctaaagta atagcaacag
    12001 ctccgacaat gaagcaactt tacgatgtac tttgggcaga ggtagctaaa tggttaaatg
    12061 atagcttgat caaaaactta ctgaagtgga caaagaccaa aatttatatg gttggtgatt
    12121 cagagcgttg gtttgctacg gctagaacag cgactaaacc agaaagtatg caaggttttc
    12181 acgaggacca tatgttgatt gtggtagatg aagcttctgg tgtgtctgat ccaattatgg
    12241 aagctattct tggtacgcta tcaggttttg ataataagct gttgatgtgt ggaaacccca
    12301 ataatattga aggtgtcttt tatgattccc ataattcaga ccgtgataaa tacagagttc
    12361 ataaagtatc aagctatgat agtaaacgta caaacaaaga caatatagaa atgattctta
    12421 aaaaatatgg aaaagaaagt gatgttgctc gtgtccgtat ttttggagaa tttccgaaag
    12481 gtgcgttgga ttcatttatc agtcttgaaa cagttgaatt ggctacagaa aaacaaatta
    12541 gtgattcttt agtcaataaa acaaaggttg ctcatattgg tgtcgacgta gctcgatatg
    12601 gtgatgattc tacgattctc tttcctagaa ttgctaccag ggcattggag tatgagaagt
    12661 attcaaaacg tagcaccatg gaaacaacag gatatgtcat caacatggcc aagaatctaa
    12721 tgagtcaata tccgagtatt gataaagtga tgattaaagt cgatgacact ggtgtcggag
    12781 gtggtgtaac cgaccgccta gaagaactta tagaagacaa acattatcct tttgaggtgt
    12841 ttggagtgaa taacggttca acatcagaag acgattttta cgataattta ggtactcaac
    12901 tatggggaaa catcaaggaa atgttagaag aaaatatgac agcaaatctt aacggagaac
    12961 agcctgttat tgaattgcct tctgatagtt cgttaatcaa agaattaagt actcgcaaat
    13021 tcaaaatgac aagtagaagt cgtatacgtt tagaaagtaa agatgatatg aaaaagcgaa
    13081 atattggtag tcccgatatt gctgacgcac tggctttagc gttttatgag ccaccaagtc
    13141 actatcaatt tattcaattt taggaggtga gcttttgatt agtacagtat tatctttaga
    13201 gagatataag aagctacgtg ttaaatatgc aacacaaatt gaagatggaa tgtttgatcc
    13261 gaatggtttt atagaagata tgaaaccatt ttttgctgat cgcgaaagaa aatatctagc
    13321 ttatactagc gaaaagaatg aaatagataa tagaccaaag cctaacactg atattgtaaa
    13381 agttaataat aaacttcatg ctggtatgta ttcaattgtc gtagaccaag cagtcaatca
    13441 ttttactggt atacctatca aatgggatta cgatgtatcg gaacaaaaaa gaacactcat
    13501 tcaaagatta aaagataaat tcttaaaaaa tgatatagaa cttccgacag ttccagaagc
    13561 ttttaacaaa ttaacaagca atcttgattc catgagattc gcaatgcttg attctgaaac
    13621 tgcaactttt caaggagctt gtggagtagc tttccgattg ctagagcctg tggaagaaga
    13681 tgatggttgg aagttaagag caagtaatat tgaaccttgg agagcagaaa gatatggaaa
    13741 tgccggaatc tatatcaaag aaaagtatga ctcttaccag aaaaaatttt ttcaagaaat
    13801 gaaagttatg acaagaaata aaattctgac atatgcttgc tatggtgatt tgaattttgt
    13861 tacaagcgga acgttcaaaa aaattgatga gaccgataac cctttgggga cgattacctt
    13921 ggcagaattt aaaaataata cgaatcgtta ttgtgatttt gaagtagctg aggaaattgg
    13981 agatgcaatt gatcgtgctt tgtctgatca acaaaacgaa atcgaacaat ttaagcttgc
    14041 gtacatgctt gttactggca caacaatgag caaaggcact gctaaagaaa tgatgaatca
    14101 gctagggatt atcaacttaa aagcccctac tgcaaaagct gaatatgtca caaaaaattt
    14161 agcaaaagat ttcaatgaat atcatatgga tctattgaaa aaacagtttt acaccatttg
    14221 taaagcaatc gattttaacg atgaggtgtt taaatcaaac agttctggag aagctcgcaa
    14281 gtggcaaatc attagcctag aagcgaaaac aaatactaaa gagcaatatt ttagagaagg
    14341 attgaaagaa tgcgcagaaa caattgctgc ttttcttaag tttcatgaca aagtagaaat
    14401 tgagcctgaa aaaattattt ttactttctc tagatctttg ccaactgatt taagttattt
    14461 agctgaagct ttacctaaac ttgcaccata cgtatccaaa cgaactattc agagccaaat
    14521 tccatttgta acagatgttg attatgaaaa tgaaatgatg gaattggaaa gtggaagtgc
    14581 ttatccagat agtgaataca attttggcgg aggtggcaat agtgacgata gaaacgaagt
    14641 attggaccaa acgtcgagaa ctggaggatc aagcaaggct caaacaagaa aatcagacac
    14701 ttaaaaaatt aactagtgta tttcctgaag cactgaaaga gatacaagca aaactattat
    14761 cacaagctga cttacacaat atcacttatc cagaaatgat ggagttttac agtacaagta
    14821 atcagaaaaa atatcgtgaa tatgtggaaa aaaattataa gtcattaaaa atgtatgatg
    14881 caaaatacaa agagtttatc gatgaatttt ttccaccatt tgactatgca aaagtcaatc
    14941 gcttattaca aatacgatca gatgtattta aaattcttgc agaatatgcg atggatgcag
    15001 atgtgaatca atatttttct gatcgcttag aggaaattct tcaaagaaca tattcttcta
    15061 atgctaatgt ttttgttcaa cttttaaacg ttgatatacc aaattattta ccagaaaatg
    15121 aaattaaaca ttatttgaac tatccatggt caggaaagac attttcaaga agactttggg
    15181 gaaatatttc atcgcttgaa cagaaactct ctaatgctat tgtaaaaagt gttgctagtg
    15241 gagaaggcgt tatacacgca ttaaacacca tgagattaga ctcagaaatt tgtgacatgt
    15301 ttaagttaga agaatcaaag tataacaaag cgatagaaaa tctcgttcga acggagtatg
    15361 caaaatttgc acaagatggt attgaaaaat catatttaga aacaggtatt gaggaataca
    15421 acgtattgac tgcaaaagat gagagagttt gccggatttg tggaggaaag gcaagtaaga
    15481 atccctataa actgaaagat gctgtcatag gtgaaaatcg agcacctttc catagtcgtt
    15541 gtagatgtac ggatgttcct aatttaccaa aattaggaaa ggatattgat gaagaatatg
    15601 accgtttatt tggcgattta ttagatgagt ttgcacatga ttcttttgga attaatttga
    15661 aacggaggaa gtagaatgaa agattttttt gaagcagtac taacaattaa tgtaaatgct
    15721 gatattgcag aagcctacaa aacagctatt gagtctgaga accatcctaa tggcttgaga
    15781 gaccattgga atggcaatta tgcctacgtg gttattggcg atcaaactgt taattatcaa
    15841 gataatactc cagttgataa gaataccgtt aatttaacga ttcaattatt atctcattca
    15901 ttaccaaatt taaaagaaac agttgattgg tatgaaaaga tgggatgtat tgttgttaga
    15961 actgactaca aagaaggaaa gtctagtaat taggcttttt tattttgtcc gaaatgacgt
    16021 taaactagcg caatactggg cttggttgaa tggtggggcg caactattaa aactcaaagc
    16081 aatgcggggc gtgaaaacga atcgtggggc gaaaggagaa tgagcatgaa acacaaatca
    16141 ttaatgccaa tgaatttgca atactttgcc gaaggtgacg atcaaaagtt ttcttttgat
    16201 gacttcaaat cttttgtgga atccaatgaa gaagctcaaa aatttattca gtcacaatct
    16261 caaagtgttg ccgacaaaca attggaagct tggaaacaaa ataacttaga taaaattaaa
    16321 caggatacca tcaaggaata tgaggaatct aagaaaaaca agtcacctga gcaaattcaa
    16381 ctggaaaaac tacaagctga atttgaagca gaaaaagcgt tgcgtgtgac aagtgataat
    16441 aaagcatttg ttgcagaaca aattgctgga ttagaactag atggagagtt aaaagagtct
    16501 atttctcaat ttatgctaaa taatcttgtt agttcggata cagatttcac taagaatgct
    16561 gttgaaggtt ttacaagtgt tttgaatgca attaatgaga aacatgcaga tgcattaaaa
    16621 gaactacaaa tgaagtctgc atttggtgga actcaacaat cgaataacca ggttcagcag
    16681 aacaatgaaa cattaacaaa tccagaagaa caattaggac aaattcttca acaatttaac
    16741 taggagagtg aaaaattatg aaaaaaacat ctttaaataa tttagagtat ttggatattt
    16801 caccagcgat taatgctatg caagtaccaa atacaccttt tttaagctat ttacttggtg
    16861 ctggaaaaac agagccagca aactcgacag aaattaaatg gcgtgaatat gatatcaaca
    16921 acgatgattc ttctgaaaaa cttgagggcg gagaatatcc agatgctgaa tcaggtcgaa
    16981 cttggtttaa caactatact gaaattttta gaaaatcaac ctctgtatct ggtacattag
    17041 atgctattaa tgtgaatgga gtcggaaatg aattaactaa tcaagtagca ctacgtggta
    17101 tggaaatgaa aattgatttg aaccgaaaat tgattactgg tgtaaaagct gatgaaaatg
    17161 gttctaaagg tcgtcgaatg aatgggattt tgaacttgat caattcagca aataaggcag
    17221 aaacagccac tgcgggtgca gtaacaagaa aagatatcga tactttattt aaattgatgt
    17281 atgaaaaagg ttatatggga gaaaaactat gcttgatttc tccagatatg caggagttaa
    17341 tgactgatga gttagatgga aaatcaacaa aaattgttca gttcggggaa agagtaactt
    17401 ttggattgca aattggaaat atcgtgtcta attacggtac aggtattgct ctactagaac
    17461 catcattgcc aaaaggaaca attgccgcaa tcgatactaa ttatgtgaaa ctacgtccat
    17521 tacgtgaatg gagagcagaa gaacttgcaa aaacaacgga ttctagacgt atcggtcttg
    17581 taggtgaata ctctcttgaa tacaatgctt caaactctgg ggcaatttta aatttaaagt
    17641 ctgaataaaa gggagttagt actccctttt ttgataggag gaattacagt ggtaaaaaaa
    17701 gatgaaacta aaaaagatga agtcgtgaaa tatagagtag gtaaaactaa aaattttgtt
    17761 gggtttgttc atcctaaaac tcgtagattt atcacagcag attcaaataa cgaatttatc
    17821 atttctatag atgataaaga agcaattgca attttggaag atgcaattga tgttaatgaa
    17881 atttaggaag tgatctgatg gatgaatcgc taaaaacgga aatcattgag tctacaaaag
    17941 aagattttcc agatttgagt gaagaacgca taactaattt attagaaata attttgctag
    18001 aaattgaatc atacaacact tgtaaaaatg atatttcatg ggaaaagtta aaaagcgtga
    18061 ttagtgaagt gttgtataaa ataataaaaa atgaatcaga aaaaacagta tcttcagtta
    18121 gacgtggcga tacaacgatt agttatgctt caacaacaaa tgatgttagt gagttacttc
    18181 taggctatgg tgatttgata cgaagagtta ttggttgtgg aggattggag tttttttaat
    18241 gaatgaagca gatattttag aaactactta tgaagatagt tgtattattg aaagactgac
    18301 ggacattgaa gattctaata caaatattac tattcaagat tacaaaaaag tatatgataa
    18361 tcctatttct tgcgctcttt cacaaggtca aatcgatgga ctagcagtca tagaagatgg
    18421 agagatggta aatgtttcaa ctgacacata taaattattt gttcatccta agattaaact
    18481 aaaaaaagga gatcgaataa caataactca aaaggccagt ggcttaattt tttctctatt
    18541 tgctactaag cctttttact atcctagtca ttgtgaagtg aatttgatag gaagtgagaa
    18601 aaatgggtaa tctcaaatat gaatcaaatg cagaaaagat cattgagaat tttaaaaata
    18661 tgactgtaat tgctcaaaaa gaaggaatat ccttcgttaa cgattcaatg aataaagtcg
    18721 ttagtttagc taaaccatta actcctgtaa aatcaggtaa tttaaggcga ggatatcgtg
    18781 tagtaaaagc tagaaaacta tcaagcggtc gaattgttgg agaagttata aacaatgaac
    18841 attattttaa atatgtagaa gaaggtcata ggactaaaaa tggtggcttt gtcaaaggga
    18901 aattcatgtt aactcgtgca acgaatcttg caaatatgtc ttatattcct cgaagattta
    18961 aacaaatggc aataaaaatc gttaagaaag gaaagtaaca tgaaagatga aatcattgct
    19021 gcaatcagta gcaaattaaa agaaatctat cctgatggga caatatatct tgattcagtt
    19081 atgcagtcaa ctaaagattt ttatttcgtt ttatcagtaa tggaatctgg aactgaaaat
    19141 gtaggaattg atattcaaaa tgtttctttc ttaattgata ttgcattgat tgataataac
    19201 cctaatagaa atttaattaa tgaattagtc tcacgttgtg ggactttttt taatacgatt
    19261 acaatcgatg agcaaatatt atttccaaaa gcctatttac ctgatgaagc agatggtgtt
    19321 caacatattc gttttacatt agaatttcca caatatattg aatggagtga aagataaatg
    19381 ggagaaaaaa gaagtaaaac cggaattatt tctgtcgaaa aacctacttg gtttcctttg
    19441 gaagatgaga cagggaattt tccggtatat ggtactgcgt tgccaatggg aacagcagta
    19501 agtatcaaac caacagctaa ttatgaaaca acacaagatt atggggattc agtggttcaa
    19561 gatcaattta cagcttttgg tggtgcagaa gttgaactgg aagcaaatgg atatactcat
    19621 aaagttttat ctacaattac tggagggaaa attgttaaag gtggtgcctt gcgttctgga
    19681 gaagatattg cgcaagatgg tgcgtttgca tatagacgta aaaaatcgaa tgggaaatac
    19741 cgttatacgg tcttttataa aggacagttt gctctagatt cagatgaaac atcaacgatt
    19801 gaaggaagta aagtaagttt tactcatcca acttggaagg gttcatttgt agatgtacca
    19861 ggacttggat atatgtattc agttgatgaa gatgatgaag gcgtggataa agcaatgatc
    19921 ggaaattggt ttacaaaagt agcaattcca attgaagaag cagaactttc aggaggtaca
    19981 gaataatgtc aaaatatcaa acaacgatta aattaacgaa aaaagacgaa gaaggtaaat
    20041 atgagcaagt acaatttaaa tctgctgaat ttttaccagg aacagttgta gaagatgctg
    20101 caggagttat ggaagaaatg caaacagcga ctgataagca atcagttaaa aaagctttaa
    20161 gtcgtgctta ttcatttatt gcagatactt tatttgaggg acaatttact ggtgaagatt
    20221 attgcaaagg aattgatgct cgtgagattg cctcattgac aggaaaatta ttgaagtctg
    20281 ttactgcagg ttttgatgaa acttatacag agacgaaaaa aaagtaagtg aggcgctcaa
    20341 gtcaccttca tttaagtatt cgattactta ccgagaatta gatataaaga cgcaattact
    20401 cgaagcaggt tggacgttac cagaaattga acgtactgac ttggatgagt taatgcgtct
    20461 ttttgctttt agagatgcgg taaaagagca tgaagatgtt gagtactatg ataatttcac
    20521 tcaattttag gaggtgatac tttgaataac gatgacctaa ttctgaagat gatactagat
    20581 gaatctggtt ttactgccgg tatgaataat gctgtcaaaa agttgaactc ttttgatgaa
    20641 acaatcgaaa gaaaaagtag aaatagtggc agttcattag gtagtatttg gaaaatattt
    20701 gctggaagtt ttctagctag cggagtaact agaatcgtag gagctggctt tgatctaatc
    20761 aagggttcca taagtggagc ggttgatcga gtagatacga tgaataacgc tctacgaaat
    20821 ttccaaaata tgggatttag taattcagaa attatgaaga atatcggaaa gaatgggctt
    20881 ttatctcaag gtattcaagg acttcctact gctttgaatg atgcgataag tcatgttcaa
    20941 cttcttgctt cttctacagg tgatttaact cgttcaactc aaatatttaa agctttaaat
    21001 gatggaattc ttggtttcgg tggttcaact gatcaagtta atgaagctgt tattcaatta
    21061 tctcaaagtt tctcaaacgg aaaagtagac gcacaaactt ggaactcaat gatcaacgct
    21121 caacttggac ctactctttc tgctattgct aaaaagatgg gaattacaat gggagatctg
    21181 aaagaaggtt tatctcaagg taagatttct gttgaagaat tccaaaatca attaatagaa
    21241 atggatacca aaggtggcgg aggacttaaa tcattaagtc aaatcgctaa agattctact
    21301 aagggaatta aaacctctat acaaaatgca aaaacagctg ttacacgtgg tgttggtgag
    21361 gtaatagaag gattaaataa agcattagta gattcagatt taggtggatt taagggaatt
    21421 attgataaag tgggcagttc aatggaatcg ttcttaaaag taattgctgc aaatattcct
    21481 acagcagtat catttttaag taatttattt aacgaaattc aaaaatttgg ttctgctttg
    21541 aaattcatga tgccctttct tgttcctgca gctaccgctt ttggagcgtt catgtttcaa
    21601 cttaaaggta taccagcaat aataaaaagc ttcaataatt ttaagaatgc cataattggc
    21661 gttggaaatt cattaaagat tatgggggca atagctgctg ctaatccatt tgttttaatt
    21721 attggtgcag tcgttggtgc aatagctttt ttcggttact ttatggcaac caatgaagag
    21781 cttagaaaca aggttatatc tatttggaat gatgtgaaag attccgtaat tggtgtatta
    21841 aaaaatataa aggactgggg aattgatact tggaattctg ctaaagaaat ggcatcaaat
    21901 gcagttgagg gtgtcaaaga tgcttggtca ggaacaaagg aatggttttc taacacctgg
    21961 aaaggtatta aggatggggc cacaggttta tttgataaaa cagtagagac ttcaagaaat
    22021 gcagtcgata gtgtaaaaaa tgcatggtct aatatgaaga aatggttttc tgatacttgg
    22081 caaagtataa aagattcagc cagagaaaaa tggaatggaa tcaaaggttc tattatgtca
    22141 gttgctggtc cattgattac aggtataaag aatgcatttt tacatgttac tttttatcta
    22201 gagaccttat ggaataattt agttgagatt ggtaaaaacg tctttgagat tttaaaaaat
    22261 gttatacttg cgccggtttt gtttattacc tccatgattt ctggtggatg ggaagaaaca
    22321 aaaaataata tgattgctgt ttggaataat attaaagaaa gtgccataaa tatttgggaa
    22381 tctataaaga atatatttgt aagttatttt acaaatattt attttgctgc actcaatatt
    22441 tggacagggt tcaagcttac attgataaat atttggaatg aagtggtaaa tcaagctaaa
    22501 tcgatttggt taaacataaa gtattttttt attaatcttt ggattgatat aaaatatttt
    22561 gcaattcaga aatggattga attgaagttt tctattattc aaacttggat cgatttaaaa
    22621 tataatgcca ttactacttg gaataatatt aaacagtttt tcaaagatac ttggaaaaat
    22681 attaaagata cggcatacaa tacgtggatt tctataaaaa ataccatgat taatacatgg
    22741 aataacatta aggactcttt ctggaatatt gttactggaa ttgttaattc tgctgaaaat
    22801 gcatggacaa atctaaaaaa tggtgtttca aatgctatta atcgggtaaa agaaatcttt
    22861 aattcgttaa gggaagtcaa tttatttgaa attggcaaga acatcattga tggacttata
    22921 aatggtgtaa aagaaaagtg gaatgctttg aaagatacta tcaaaggtat tgcaggtaat
    22981 atcaaaaatt ggattaaagg agctttagat attcattctc catcaagatg gatgcgtgat
    23041 atggttggta aaaatattgt tcaaggtatt atcgttggta ttgataaaga gcaaagtaag
    23101 ttagatcaaa ccatgacaaa tttagtaaaa acaccgtctg ttcaacctgt agtaaatgga
    23161 ataagtcacc taccaattac acaaacaaag caaaatatat ctgctagtga aacaaaagaa
    23221 attcatttac atttaaatgt ttatggagat ttacctgatt caatggttcg gaagattacc
    23281 acaaaaatta aaacagaatt gacaagacaa atgaaacgag atgctggtgc agtaggagga
    23341 acattatatg caacttaaga gaggacaatt ttttattaat caacattatt cttctgaatt
    23401 taatgtgtat attcaaaaca ggcctgcttc tgtttcagct agtcgagtaa ttgaattgag
    23461 agagcgagaa ggaaatgatt ctatcattat tgataaaggc tattacaaaa atgtgactag
    23521 aaagattgag tgttactata aagcaccttc aattgatatg gtgcaggagt gggaagatcg
    23581 aatcactgaa tggttagata tgtcgtctta tagtgatttt attctttact atgatgaaca
    23641 atatatttat caagctgtag taatagaagg acctgaattt aaaggaacaa gaaaaacagg
    23701 aaatattgtc ccttttgaat ttacagtgag tattcgacca tttaaggaaa attacaatgg
    23761 tagatttact attcgacaaa cagaaacttt tgaaatttat aacccagaga agtattcttc
    23821 aaaaccgctt attaaattga gtggttctgg agatgcttct ttttatatta ataaggataa
    23881 atatgatttg aaatcgttgg acagagaatt atttatagat tctaaattag aagaggctta
    23941 tcgaaaatta gatggtaatt tagaacatca ggatcaggtc accttatttt tagattttcc
    24001 atttttatat cctggaaaaa atgaaattaa atggacgaaa aatattcatt catttgaaat
    24061 aatgcctagg tggtggagaa aagtatgaaa ccaagaatat atagtcctac tgaaacagat
    24121 ttctcaacga atggcttagg aattttaaag gattgtacaa gatgtggaat atatgaagta
    24181 gctaatggaa aatatgaatt agagttggat tatcctttag gaactagatt tgatgaatat
    24241 tttgaaaatg actatcaaat aaaagcaaag ccaaacgatc aagaagagta tcatatcttt
    24301 tttattgatg ataaagatat agatactttt ttaaatacag taactattta tgctcagagt
    24361 cgtacaaatc gacttggaag acgggtagtc actcttgtgg aagtggactc taaaactggt
    24421 caagaagcga tatcaattat tgaaactaaa atggataaaa aatctgacat acgactttat
    24481 tctgatatta cggctgtttc tagcacaatc tttgaagcga gaaatgtttt aaattgtatt
    24541 gctggtgaac aaggatcatt gcttcaatat tggggcggag aaattaaacg tgaaccattt
    24601 aagctttctt tgttaaagcg aagaggtcgc aataatgttg gaacgattcg gtatggaaaa
    24661 gatatgtctg gtttgaaggt caaattagat tggacaggta taaaaacaag aattattcca
    24721 tatgctgatc ctcaaagtga agtaggtacg actaatcgaa tttatggttc gccagtagat
    24781 agtgcctata ttaataacta tcctgatgtc tatacagaac atgttcagtt tacagaagaa
    24841 caaggagtaa aagacattaa gagcttaaat aaaatagcta aaaattactt taaaacgatc
    24901 aatcctggct gtgataagcc taaagtttct attacggttg aatttgataa gttgactgat
    24961 agtgaagaag cgaaagaatt tgcgaagatt agaaattatg gtctgtttga tacatttaaa
    25021 atatatcata aaaaatataa tatttatctt gaatcaaagg ttagtggact acaatacgat
    25081 tctttatctg aaaaaacttt gaaattagaa gcaggagaca ttcaagttgc tttttatcag
    25141 caacaagctg taactattca ggataaatta aaagattatg caacgaataa ttatatgagt
    25201 gattttaatg attatgtttc ttcaatgatt acaggtcaag gcagtgcagg aggatatgta
    25261 gttttatggc caaaagaaaa accttccaac atctttatta tggataatcc agatttagaa
    25321 aaggcaagag aagtactaag aatgaataaa aatgggattg ctttttctaa gaaaggatgg
    25381 cgggggcctt ttaattcagc ttggacatta gatagtatat ttaatgccaa ttttatacaa
    25441 actggattaa tcaaagcaga tatctttcaa aattctttta acaagactgg agatgtattg
    25501 aaattagtta atggactact ccaaatttgg aacaacaaaa agaaaataat ggagttaact
    25561 aaaaaaggaa tggaattttg gaattctaag ggttcaattg gaacgattgg aacaactgat
    25621 tctgttggta atccttttcc tggggcttct actccaaccc ctattgaaga taattcttta
    25681 gttattcgta caaatggaga cggcaaatat attttgattt ctcctaaagt aggaaaagga
    25741 ttagttttat taggaaatgg taaagcaatt tattttggag acttagatgt acaaggaaaa
    25801 cttacagtta aaggaaaaga aataattcct ggacaaggtg gtggtccatc gggaggtgga
    25861 gaatctactg gtgggtatcc tagtgaatta aaaacagatg cagaaaagag agcttggaga
    25921 atttacgata ttttgtgtaa taacggattt acgaaacaat ctgcatgtgg aatattgggg
    25981 aacattcaac aagaaacagg aggaactttt gatcctgata ctgttcaaat aggtggacca
    26041 gcatacggat tagttcagtg ggatggttct tcatatcctc ttgttggtcc agcaacatgg
    26101 gatggaaaag tttatgttca aaacttattt aatgctgcag gtattaaaga accaataacg
    26161 agcttagatg cacaagttcg attgcttatt tggacattta caaatggaca atggatgggc
    26221 gtagtacaac ctacgacggt tgatggattt aaggcctgta ctgatccaag acaagcagca
    26281 tatgcttttg aacgaaacta tgaacgtccg gcagcgacac atcctgaacg tcaagattat
    26341 gcagttaact ggtataacaa atttaaagat ttaaaaccag gaggagctac tggagaagca
    26401 ggactaaaac atttagagtc tttgattgga caacgaattg gcaatggtca gtgttatggc
    26461 ttgtctgcag aatattcagg atatctgggt ggttgtggca tgggtgctgg aacaaaatat
    26521 ggtttaactc atgtgatagg aaatacttct gcagcatctg atattggtat tgcctatgat
    26581 tggtctgctg ttggttggaa agtgattcaa aaccctagat atgatcaatt agtagttggt
    26641 gcaattatta attgggcaag aggtggacaa gtgggttcat ggtttgcaga tggaacttat
    26701 ggacatactg gcgttatccg aggcttagct aatggtcgta tgcaaactta tgaacaaaac
    26761 acagagttag gtatgatttg tggaaagtta gatcgccagt attatagtgc aagtgcaatt
    26821 tcttccattg tcataccacc aaaataggga ggtgatttaa tggcaaagtg gaatgtcata
    26881 ttaagtacaa cagaacccta taattacgtg gggatgattc aagttcgaca aggcaataag
    26941 aatacagagg ttatggaagc gactatagtt gaaaatggtc ttccctacga tttatcagaa
    27001 tgtaaggtat attttgaatc agttgtaggt gggaaatatc cagtccaatt agaaacaaaa
    27061 attgtggatg ctaaaaaagg gaaaattaac tatatttttg ataaatattc catgcagtgt
    27121 ttacatcgac aaacagccaa tttcattata tttaaaggag aagacttgat tggaacaact
    27181 caagacttct cttattttgt cattaatgct gtttcaaaaa cagaaggaga aatgggttct
    27241 tattggcaat caatcgaaga tttaattgcg gatatgacgg actttattaa tgaaaataaa
    27301 ggcgatttta cggactggat gaatgaaagg aaagaagaat ttgaacgttg gagacaagaa
    27361 caggaacaca gtttccaaga ttggagagaa ggacaagaat cagactattt ggcatggttt
    27421 gaatcaatca aggatatttt aaagacgatt gatccaggtg gagtcatgtt agccgaacta
    27481 acggatgcgc gagtagatat tcaaggagtt cgtcatgcgt ctatttcaga gcgtttgctg
    27541 gcagatatgg actatttata tcagaaattg cgagcaacgc ttttcacgat tgaatacggg
    27601 gagattgaag tgactgatat tttgcaggat gatctctttt cagataatca tgaagtcgaa
    27661 aaagttggaa ctgtagcatt cccgattgaa gaaggagcct tgatcatcgc aaccgttgat
    27721 gatccaaagc aaaatgtgtt cactcttgag aaagttgggg tgatctaatg gctaaaacta
    27781 aacgaatgat ggaaacggat gaaaaaacgg gtgtacaacg ccaattcttt ccaatcacac
    27841 atgcttccgc agttcttggg ttagaagaaa taatagcagg agaagcaaca gttttatctg
    27901 ttaatggaaa aattggagcc gtcgtcatta ctaaagaaga tttgggatta gagaatgttc
    27961 tcacagaatt accctatgca agtgaagaag atgacggcat tatcacggca gaaatgtatc
    28021 aaaaaatttt aaacagtgga gaaggtgact acgtgttgcc agttgccact atcgaccgtt
    28081 tgggtggcat aaaagttggt gaattattga cgattgatga gacagggaaa gtctctgcag
    28141 tcagacaatc tgatgtcaat ttttcgctgg agttaaaaga aaaactcgat tcactgaaaa
    28201 attatactgc tggagaaaac atcactattg atgaagatgg aacaattagt tctacaggtg
    28261 gtagtgggac tggtggtgtc aatcagtcat atgtagatca aaaattccaa gaagctgtaa
    28321 atcaagcaga aaattacaca aacgaaagaa ttccaaattt tacttttgaa aaaattgggg
    28381 aggtatagag aatgacagat atcgtaaaaa taaaacaaag caatgtacag gtttatccac
    28441 aaactcattg gaatgctata gaaggcaaac caacaacggt gaagggagat aaaggcgatc
    28501 ctggccaagc agcaacaatt accataggaa ccgtttctag tggttcaacc gcttctgtta
    28561 cgaatgtagg aacatcatct gcagctagat ttaattttgt tttaccaaag ggagataaag
    28621 gtgatcctgg aataaatgcc acaactacag ctgtagctac aactacagca aatgggttga
    28681 tgtcgtccac agataaaact aagttggatg gaattgcagc tggagcacag aaaaatccag
    28741 gtaatgctac aactacgaca gcaggtttaa tgtcagcaac tgacaaagct aaactcgatg
    28801 gattagccaa tattacattt gagaaagtgg ggacggttta atggctgata ttgtgcaatt
    28861 aaaagaagac ggagttgcta aatacttaaa aacgcatgta gaagctattg atggtaaaga
    28921 agcattggtg cagacagatg gagaccaagc cattgcagga cataagaatt tttcaggttc
    28981 tgtaacaatc aataataaac gtgttttgac gactgatgat aacagatatg aagtggtaaa
    29041 tctggttgtc actaacggta atacagggac agcaaagctt tatcgtgaag gaaaaacagt
    29101 ttctatatat tttgtggctt taaacggaaa aagtagtggc gggaatgatt cggttatttt
    29161 aactgttcca gaaggctatc gg
//
LOCUS       DACCVZ010000028        28859 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.028, whole genome shotgun sequence.
ACCESSION   DACCVZ010000028 DACCVZ010000000
VERSION     DACCVZ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.028"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(20..1123)
                     /locus_tag="IVW63_001293"
     CDS             complement(20..1123)
                     /locus_tag="IVW63_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAP7859576.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            complement(1345..1815)
                     /locus_tag="IVW63_001294"
     CDS             complement(1345..1815)
                     /locus_tag="IVW63_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HAP7859577.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            2072..3391
                     /locus_tag="IVW63_001295"
     CDS             2072..3391
                     /locus_tag="IVW63_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HAP7859578.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            3832..5472
                     /locus_tag="IVW63_001296"
     CDS             3832..5472
                     /locus_tag="IVW63_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAP7859579.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            5626..6948
                     /locus_tag="IVW63_001297"
     CDS             5626..6948
                     /locus_tag="IVW63_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HAP7859580.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(7010..7441)
                     /locus_tag="IVW63_001298"
     CDS             complement(7010..7441)
                     /locus_tag="IVW63_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7859581.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(7505..8341)
                     /locus_tag="IVW63_001299"
     CDS             complement(7505..8341)
                     /locus_tag="IVW63_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAP7859582.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(8531..8833)
                     /locus_tag="IVW63_001300"
     CDS             complement(8531..8833)
                     /locus_tag="IVW63_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAP7859583.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(8859..9290)
                     /gene="ruvX"
                     /locus_tag="IVW63_001301"
     CDS             complement(8859..9290)
                     /gene="ruvX"
                     /locus_tag="IVW63_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAP7859584.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(9287..9553)
                     /locus_tag="IVW63_001302"
     CDS             complement(9287..9553)
                     /locus_tag="IVW63_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAP7859585.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(9807..10532)
                     /locus_tag="IVW63_001303"
     CDS             complement(9807..10532)
                     /locus_tag="IVW63_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HAP7859586.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(10898..10968)
                     /locus_tag="IVW63_001304"
     tRNA            complement(10898..10968)
                     /locus_tag="IVW63_001304"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10934..10936),aa:Gly,seq:ccc)
     gene            11085..11837
                     /locus_tag="IVW63_001305"
     CDS             11085..11837
                     /locus_tag="IVW63_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAP7859587.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            11853..12332
                     /locus_tag="IVW63_001306"
     CDS             11853..12332
                     /locus_tag="IVW63_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAP7859588.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(12583..14163)
                     /locus_tag="IVW63_001307"
     CDS             complement(12583..14163)
                     /locus_tag="IVW63_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HAP7859589.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(14156..14899)
                     /locus_tag="IVW63_001308"
     CDS             complement(14156..14899)
                     /locus_tag="IVW63_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7859590.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(15075..15851)
                     /locus_tag="IVW63_001309"
     CDS             complement(15075..15851)
                     /locus_tag="IVW63_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7859591.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(16099..16935)
                     /locus_tag="IVW63_001310"
     CDS             complement(16099..16935)
                     /locus_tag="IVW63_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HAP7859592.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(16946..17875)
                     /locus_tag="IVW63_001311"
     CDS             complement(16946..17875)
                     /locus_tag="IVW63_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAP7859593.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            18067..18420
                     /locus_tag="IVW63_001312"
     CDS             18067..18420
                     /locus_tag="IVW63_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAP7859594.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(18494..19150)
                     /locus_tag="IVW63_001313"
     CDS             complement(18494..19150)
                     /locus_tag="IVW63_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAP7859595.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            19376..21310
                     /locus_tag="IVW63_001314"
     CDS             19376..21310
                     /locus_tag="IVW63_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP7859596.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(21396..22619)
                     /locus_tag="IVW63_001315"
     CDS             complement(21396..22619)
                     /locus_tag="IVW63_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HAP7859597.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(22613..24511)
                     /locus_tag="IVW63_001316"
     CDS             complement(22613..24511)
                     /locus_tag="IVW63_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HAP7859598.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(24505..25623)
                     /locus_tag="IVW63_001317"
     CDS             complement(24505..25623)
                     /locus_tag="IVW63_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAP7859599.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(25706..26539)
                     /locus_tag="IVW63_001318"
     CDS             complement(25706..26539)
                     /locus_tag="IVW63_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7859600.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(26532..27449)
                     /locus_tag="IVW63_001319"
     CDS             complement(26532..27449)
                     /locus_tag="IVW63_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7859601.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(27676..28800)
                     /locus_tag="IVW63_001320"
     CDS             complement(27676..28800)
                     /locus_tag="IVW63_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP7859602.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
BASE COUNT         8840 a         5814 c         4922 g         9283 t
ORIGIN      
        1 ttttttcgtc atttgtttct taaataaaac gattctcacg caattttatt tttttgatat
       61 cttctactgt ttgtgttcca gctaattgca tgaccatttc caattctgtt ttaaagaaat
      121 caaacacttg atggactcct gtacttcctc ctaaagacaa tccataaata acgggtctgc
      181 caatagcaac aagatctgca cctgatgcga ttgctttgaa aacatgctgt ccgcgtcgta
      241 caccgctgtc aaacacgatt ggtacacgtt tatctactgc ttctgccaca tattgcaacg
      301 aatcaaacgc tgctggacca ccatctagtt gacggccacc atgattagat acccagattc
      361 cgccagcacc agattctaat gaacgataga catcttcttc tgactggaca cctttcacat
      421 agactggcaa atcagaatga gcagcaataa attctacatc ttttggacta agcttctgtt
      481 tggaagattt gtacacagca tccatcgttt ggcctactcc tgattgataa gcctgaacga
      541 tcggcattgg cagtgggaag gtaaacccat ttctgcggtc tgtttcacgg tttccgccaa
      601 ctgttgcatc cgctgtcaat acgattgctt ttgctccatt acgcttggcc acttcaagaa
      661 tatccaaatt gatcccatca tctttgctca tataaaattg aaaccattgc ggtgctttct
      721 ccccgcctgc ttctcttatc tcttctaatg tacaagaagc gtaagaactt gctgtataga
      781 tcgtcccaaa atctgctaca ccttttgcag aagctttctc cgccttcaca tgagctaagc
      841 catgagcagc aactggtgcc atgatgattg gtgcagtcag cgtttctttg tcaaaatgtg
      901 tagttgtatc gggtaattct acatctctta atacatgagg aataatcagc tgatgattga
      961 atgcccgttc attttcttga taagtaaata agtcgccagc accactgctg atgtaaccat
     1021 aaccaccagc tggaatcact tgtgaagcgg ctatttctaa atcttccata ttgataaaat
     1081 ccactattcc ttcatttgta cctgcttgat acgttttttc catttcaatg ccttccctct
     1141 ataaaaaatt gaatgaataa tatgatagcg tttacacact ttatattact cttccgtatt
     1201 gatacaggca aataatctgt ttacatttca gtcattccag ttgttactac tctgaaagaa
     1261 atgtttagaa cacaaataga taaaaaacga tgggattttg acaaaagtcg tgtcaaagtc
     1321 ccttttacga aatactgtgg atgcctattg aaataagtgc gggttgtttc tttgtatttc
     1381 aatcgtttct tgccattctt cgtttaattt tggattaccg ttttcttcct tgaacgcata
     1441 aggtcccaat ccaaaaagct cagttagtat ttgattcacg attccatata gctcggtgtg
     1501 atcggacaca tgattattga agatcatctc attatcacca cgtttgaatc tcacattcgg
     1561 gctctcatga tgaacctcta tgcagttttc cccttttttt aactgacgga tttctgaaaa
     1621 catctcataa atatcttctc caataaaacc ttcagcaagc gccagactgt ccacaagacc
     1681 gcctactgtc aactcagaga ttatcgcttt gttggcacca agctttaatg tatagcttgt
     1741 tgcttctact acgccgcatg cattgcaacc accttctgat agttcgcttt ttctgatcaa
     1801 ttgaacttct ttcattttct gttcctcctc ttagttttct acttatgtat tttttatcac
     1861 ctgacgtaag tgtattttat cgtcacgatc acgtgattta ttcttcagag attctacctg
     1921 aataattcat acttttaatt aaaaccatgt gaaactgcct cacggcagct tacaattact
     1981 ttttcatctt cacccgttaa gtgatgaaaa aagaacccct ttctgctatg gttaaagtga
     2041 ctaaaccaac caaaagaaag gagttctttt catgactagc ttacacaaaa accaagtaaa
     2101 attcaattca aatatcacta tttctcatac aggtggtcaa ttatcgagtg attcgggtct
     2161 cgtcctagtg aaagagctga tgaacatctt tggtttttct gaactggcta agcaacacat
     2221 tcacattgaa gacgaacgag cgtattttac tcatgacaac ttatccatac ttgagcagtt
     2281 cattatgcaa ttaattgctg gttactcagc tgattctgca gctaatctcc tgagacaaga
     2341 tcctgtgttt aaagctgttt tagataggaa agaactcgct tctcaatctt cactttcccg
     2401 atttttagat cgactatctg aggagaatat ccatgaactt caagctttga accaagaact
     2461 tatcgataaa gcacgcctca tccgtaatga tacggaatta atcattgatt tagattcgac
     2521 ccattcagat acatttggtc accaagaaca aacgaattat aatacacact accaaaccta
     2581 tggttaccat ccattggtag cttttgacgg attgactggt gacttcttaa aagctgaact
     2641 acgttcagga aatcaatata catcaaaagg cgtaaaggag tttctcacac ctttattaga
     2701 gcactataat cactctctac caaacactga catcttggtt cgtggagaca gcgggttcgc
     2761 tacacctggt gtgtatgatt cgtgtgaatc aaaaaagagt cattatgtta ttcgactgaa
     2821 gaataatcgt agactaggtc aaatagctga gaaatcagta ctttatggcg ataatcaaaa
     2881 gtgggaagaa cgagaagttc agtacttctc gaccacttat caagcacaat cctggtcaca
     2941 aagtcgtcgc gtgtgtatac gctcaacacg tgaagcgggc gaactactct ttcgacatga
     3001 atttatcgtg acgaatctat cagaaaatgt ttctcctgat accatctttt ctatctatgc
     3061 caaacgtggc acaatggaga acttcattaa agaagcgaaa gctggctttt actttgacaa
     3121 aacagacagt cctcgctttt tggagaatca tgtccgaatg atgctcagct tgatagctta
     3181 caacttagtc aacttcttaa gaacgattgg ctttgaagaa gtccaaaagg gaatgaccat
     3241 tcattctatt cgattgaagt ttctgaaagt tgctgggaaa ttagtccaaa cgggtagacg
     3301 agtctatctc aaattatcta gttatcatgt gtatcagaat gaattctaca gggtctttgc
     3361 tcgcctgagg cgagccagtc aatggatcta atccaacaat ctaacgattt ttttactggg
     3421 aagttatcca gggagaagta tgctcaaaat gccttacacc caaaatttat tcctcaatat
     3481 ttttgaacag tgaatgtttg aagtaacttt ttagtcaaaa tcagttgata gggatattag
     3541 tgatacatat ttcaataaaa tgtgccaaag aattaaagct atgaattatt caggattcta
     3601 tttatctatc taacatatcc tttattcttc tacttttctt tctttagcat ataagagata
     3661 cgcatagtaa tcaagcaagg attgttgata taaaaagaac aaataccgct attttgattt
     3721 cttttgactc tattactcat ataaataaaa tttattatac ctgctctttt tgactatatc
     3781 ctcatctgac tcctatactt cgtttgtatt aaaacttagg aggaatcatt catgcttaca
     3841 gggctaaact tattaaataa tccttttcta aataaaggaa cagcttttac aaaagaagaa
     3901 cgggcaaaat acggaatcac tggtatgctt ccaagtactg tccaaacatt ggaacaacaa
     3961 tctgtccaag cttacggtca atacttaagc aaacagaccg atttggaaaa acgtatcttc
     4021 ttaatgaatc tattcaatac gaaccggaca ttgttttata aattgatggg cgaacattta
     4081 gttgaattca tgcctgtcgt ttatgatcct gtcgttgcgg attcaatcga acaatacaac
     4141 gaaattttct tgaaaccaca agatgctgta tttctttcaa tcgacgaacc agaaaatatc
     4201 aaagcaagtt tgaaaaacgc agcagatgga cgcgacattc gtttgatcgt tgtgacagat
     4261 gcagaaggaa tcttaggtat gggtgactgg ggtgtgaacg gtgttgacat cgctatcggt
     4321 aaattgatgg tctacactgc cgcggctggt atcaatcctg cacaagtctt gcctgtatca
     4381 atcgacgctg gtactaataa cgaagaatta ttgaataatc cattatactt agggaatcgt
     4441 catgctcgtg tagaaggcga aacttactac gaattcattg atcaattcgt tcaatcagct
     4501 actgaattat tcccagaatt gttattacat tgggaagatt ttggacgagg aaatgctgca
     4561 acgatcttag aaaaatacga agataaaatc actactttca atgatgatat ccaaggcaca
     4621 ggaatcgttg tactagctgg tgtattaggt ggattgaata tatcaggtga gcaattgaaa
     4681 gatcaaacga tcttgacatt tggtgctggt actgctggtg taggtatcgc aaacatcctt
     4741 ttagatgaaa tgatccgtca aggtgtacct gaagaagaag cacgccaaca tttctatcaa
     4801 gtagataaac agggtttatt gtttgaagat acaaaaggat tgactcctgg tcaaatccca
     4861 ttcgctcgta aacgctcaga attcactaat gctgatgaat tgacaaactt agaagcagtt
     4921 gtaaaagcaa tccatccaac gatcatgatc ggtacttcta cccaacctgg agcattcact
     4981 gaagaaatcg tgaaagaaat ggcggctcat accccacgtc caatcatcat gcctttgtct
     5041 aatccaacaa aattggcaga agcaaaagca aaagatttga ttgaatggac ggacggaaaa
     5101 gctttagttg gaacaggtat ccctgctgct gatgtggaat ataacggtgt aacttaccaa
     5161 atcggtcaag caaataatgc gttgatgtac ccaggtttag ggcttggttt gattgcttca
     5221 acagctacac gagtaaatgc tgaaatcatt tctcaagcta gtcgagcatt aggcggaatc
     5281 gttgatgtaa caaaaccagg agcagctatc ttgcctccag tagcaaaaat cactgaattc
     5341 tctcaaacga ttgctgaaac tgtcgcaaaa tcagttgttg cacaaaaatt gaatcgtgaa
     5401 gaaatcacgg atatcaaaga agctgttgaa tctgctaaat gggttcctga atataaatct
     5461 ttagaagatt aagattgtta tagtaaaaga acatacagaa actttgtatg acgtctaaaa
     5521 agaaaaaagc gactgcggca aaacagcagc cagccaacta ctgctctttt gccgcttctc
     5581 tttggctttt ttcatacgat acagaataag aaaggatctg taaaaatggc acaaaaaaca
     5641 acaaccgcaa ctgcagttga ggaaaagaaa aaagaagggt tttggtcaac aaaaattacc
     5701 ggcgtaagtt tgccccttta tttgatcatg gtccttgtcc tgatcattgc aatggcttta
     5761 ggaaaattac cgacgaatat gattggccca atcgctgttt tggtcatttt cggtaattta
     5821 tttcatttta tcggaacaaa aatccctata gtcaaaagtt atttaggtgg tggctccgtt
     5881 tttgcgatct ttgcctctgc cgcgattgct acatttggga tcttacctga gtatgtagta
     5941 aaatccacag aaaactttgt cagcaatatg ggctttttag acttttatat tgctgccttg
     6001 attactggta gcatccttgg tatgaaccgt aatctattga tgaaagcttc tgttcgtttt
     6061 attcccgttg cacttatttc aatggtcgtc tccttttttg ccgtaggact cgtaggtatg
     6121 cttatcggaa atggttttgc aaattccgtt ttatatatct cattgcccgc aatggctggt
     6181 ggtgttggag ccggagctgt acctttatca acgatttatg caaatgtttt aggtacggac
     6241 gcttcttcta tcatttcccg cctgattcct gcgacagcaa tgacaaatgt cctagctatc
     6301 attggtgcag cgttagttgc tcgtgcggga caatcaatgc caaaattcaa cggtaatggt
     6361 aaattaatgg aaaaaggcga ccttggcgat ggaaaaccta gaaatgtaaa accttccatt
     6421 ccacaattag gtgtcggttt gatggtatca ttgactttct tcatcttagg acaaatctgt
     6481 aactattttg ttcctaaagt ccatgcttac gcattcatga tcattatcgt tgttatctgt
     6541 aaaatcgcaa acctattacc agaatattac gaagatgcag ctatcatgtt caacaacttg
     6601 attgtcaaaa acttgacagc agctgttctt gccggtatcg gtattgcgtt attgaatcta
     6661 aatgtattgg cttctgcttt gacatggcaa tttgttgtct tatgtttgac aagtgttatc
     6721 gcgatttcag tagtttcagg atttgtcggt cgtttgtttg gtttatatcc aatcgaatca
     6781 actattactg ctggcttatg caacaactcg atgggtggta caggaaatgt agctgtctta
     6841 tctgcagcta atcggatgga acttattgct tttgctcaaa tgggcaatcg gcttggtggt
     6901 gccatcgttt tgatcatctc aggtttcttg atgcaattac tttcttagtc aaaaaaaata
     6961 cctgatcatc aagtatcggc ttgatgacca ggtatttttt gataaaaatt tacaggattt
     7021 tcaaaaatct tttttgcatt ttatcggaat gataaccgat gcgttcataa aatcggtgtg
     7081 cttctactct gtattctgca gaattaagtc ttattgctga tattcctcgt cttttcgctt
     7141 cttctacgcc agtcatcaag gcctttccga ttcctctttt ttcagcatgt ttagacacag
     7201 caagtgccat aatattgaac atcggatcgc tgaaaatcga ttcataggac tccgcttgta
     7261 catagccagc tgctttttta gaagtaggat cttcatagac caagaaaaaa tttttttctg
     7321 gctccttcaa cagtttcttc atttgtctca ccgtaacggt taatggtaca tcatatccta
     7381 attgttccgc attgatttct cgtagtgctt ctgcatctcc taaacgcatt tcccgcaaca
     7441 tccaaatcac cagccaattt ttattttttt aaatgaattt ttttatcaca gtatactcct
     7501 tttttcactt aaaaaaagac ttttcagtga ttttgacttg cttgaatcca gatccttcta
     7561 atgtttgcaa gatgacgaaa gcattgtaaa gattgatcaa aagaaccacg atgacaatcg
     7621 cttgaaaaat aaaggtcact ttttttggag acaaaaccct gctaaatctt gctccccaca
     7681 aacctccaat aacagcagcg gggataacat aaaacaacat agataaatca aagcgcataa
     7741 agctacttgt taaagcaatc gttaccaatt ttgccagttg agaaaagaaa atcgtagata
     7801 gagaatatag tgttgcttct tttattggca atgcaaacat cagcatcaac aaagaaacat
     7861 tgactggtcc accaccaata cctaaaaaac tagctaaaaa gcccagaacc cccccacata
     7921 taaggtacca agtccatgac gtcaaatgaa attttggctg atgatgcttg gtgtagaaga
     7981 acgcaaaaac caaggtcaat accgtcaaaa aaatttggat cagctgcaca tgcttctcgt
     8041 tttcaaataa ctgtaaaaaa acttcgaata caatgttgcc gactactcct ccaacaacag
     8101 ctccactaga tacccaaccg acaatctgcc aattcagtga tttcccgctt gatacttgtc
     8161 gcacagtcga aacaatggac atcgtgaata ccgcaactgt tgagtaaaaa gaaatccctg
     8221 caacagaatg ggcgccgata agatcaagaa tcggtttgat caacacgcct ccacccatcc
     8281 cggaaatagc gccaactgtg ttcgccagaa cgatcaccac aaaataaatc agaccaatca
     8341 tcttgtattt cctttctctt gtttatatct tttagcgatt gttactcttt tcttttatta
     8401 tacagtaaaa gaaacaaacg aggcttcgaa agcttttcta ctttttaagg aaatttagtg
     8461 ctaaacgaaa aaaccgggct ctacttttca gagagtccag cttttcttac accttatcga
     8521 ttcttttgtt ctattcttct tccgccatga atgtattgaa tacttcttcg atcatatccc
     8581 attctgcgtc tgtttcgatt tgttctaact cgccttctgt tccatcttcg ttttcgatgt
     8641 atgcataagc ttgtaattct acatcttcat cttctgaaac accagctgga tataaaagaa
     8701 catagttacg tccaaattct tcttgtccgt caactgttag caagatttcg tataatgttt
     8761 catttccttg gtcatccacc aatgtgatgt gttcgtgtcc ttcgtgttcg tgggaatggt
     8821 tatgttctgt cataagatta cctcttttct ttttattatt aaaataattg cttacctgag
     8881 ccgtctaaat aattttgtaa aatcatcaca gctgctaatt tatcgatgac tttttttcgt
     8941 ttcgctcttg aagtatttgc ctgctctact agcatacgtt ctgcctgaac agtggttagt
     9001 cgttcatctt gataatcaac cggcaaggag aatagttctt tgatcttctc tccatatgac
     9061 atggaagctt ctgcccttgg tccgatggaa ttgttcatat tcttaggtaa tccaactaca
     9121 aaacggtcta cttcgtactg cgccactaat tccttcaacc gatcaaaacc aaactcttct
     9181 tctgcctcat tgattcgaat gatttctact ccttgagctg tccagccaaa gggatcgctc
     9241 acagcaacgc ctactgtctt agaaccgaca tccaagccca ttactctcat aaattcactc
     9301 catgatttga gaggtagtct ttgacaatta cttccatgat ttcatcgcgt tcgtgacggc
     9361 gaatcaaatt tcgtgcatca cgataacgag gaatgtaggc cgggtctcca gaaagcaagt
     9421 agccgacaat ctgattgatt ggattgtagc ctttttcttc caaagcccga taaacaatcg
     9481 ctaatgtttc gctcacttct tttttgcgac tatcgtcaaa accaaaacgt acggtttcat
     9541 ctgtaaaacc catgattcta cacctctttc ccgcaaggta attccagctt accttctaca
     9601 cccttatttt actcgaagaa agggaaaact acaaacaaat attccaaact tctgaataaa
     9661 ttaagaaaca cgatttgtct gatttttcct tttttctgtg gctttttcaa aagccctctt
     9721 tccataaagt atacgctata tttctttgaa agtatgtttt tacacaattt tttcataaag
     9781 ttcataaaaa attcgaattg ctgctactaa tttttcgttt tcgttgcttg ccctgtctca
     9841 taattgatgg tgtagccatc ttgaacattg tagataaaga cattgaattc aatttttttg
     9901 tcttcaatgc tttctgcttc caactgcaca cctcttgcta ccagttcatt tccctcgaaa
     9961 tgaggagtga cacgatagcg tacatgatga tttgtttcct tgatatatgc cgcaatatca
    10021 ttttcgtggg caagcatgta cggagcattc aacgaacgtg tccctgtcat taagttttta
    10081 atgttattat tttgaccagt caactggaaa ccaatcaaat ggctgcggtt gtataaccat
    10141 tgtccgtcac ttaatttctt ttgtttccaa cctgtcggat caatatacaa aggttctctc
    10201 ttttcagtag gaaacaagtc ttttcccaac atcgcattgg cttgtcctac tctgttcaat
    10261 ttgtctatat ttgaatagct ttcccatgtc cctttggaaa gactaagatc ctcttttgta
    10321 aactccggct gattcccatt gatttctatt tcttgatgtt ttccatcata ttctggcaca
    10381 tccgctactt gagaagcttg cggtgtggaa tcaaaaatgg ttgtaatttg ttggaagata
    10441 tctgaatctt tttgtgtggt ggaaataccg agtgcccctg caatcacagc agcgacgatc
    10501 cccacgatcg ccttggttgt ttttttgctc atttctttac tcctttacta acagttccct
    10561 aaatcttaac atatgttccc ctataaataa atactggaaa gaaatagaaa cagtaaaaaa
    10621 ataaaaccag tttttagacg gcttaagaat acaaaaaaag agacggattc atcgtctcta
    10681 ctcaatcaca aaacactatt tacaaggtat ttattatcat tcaaaaaatt tttcttaata
    10741 ctcaaaacta aacggcttct gtacgacctc ttggtaaaca gtgttcaaaa gcttgcatct
    10801 gcggtaataa gtccaaccaa gtcaaaaaca taagaagctt ttttgcttga ctattcttat
    10861 tacttgatgc agggcagctt tttcacagcc tcttttaagc gggtgacggg aatcgaaccc
    10921 gcgacatcag cttgggaagc tgggatttta ccactaaact acacccgcga tacaaaaaca
    10981 gtatacgcct ctttcactcc ttcctcaagt ttttttattc tttacgcttc cgatatgttt
    11041 tgtagtaaaa taaaactaat caatcaatta ttggagaaga tgctatgacg ggaaaagaat
    11101 tagatctgtt gctggacact tgtttactcg ctgggaaaat catgatggaa agcaatgcgg
    11161 agatgtatcg ggtagaagat acgatgagtc gaattgcttt agcttctgga aatttccgtt
    11221 tggtcagcta tgtcactcaa accggtctct ttattggtct tgatcgtacc tcgaccatcc
    11281 gaatggaaca aattaccaac cgttcgatta atttagaaaa agtagtaaaa gtaaatgatc
    11341 tttcacgtaa atatgttgct tcagagctaa cattagaaga actttactgc gaactgcaag
    11401 caatcgaccg agaccgttct ttctttcctg tctggttgca aatcgttagc gcggcagtga
    11461 tcagtggaac aattatggtg ttatttggcg gaaagatgac cgatttacct gtgactttag
    11521 tcattggagg attgggatac gcagcttatc tatatagttt gaaatttttt agaatcaaat
    11581 ttttatcgga atttttatct tctttattga ttggcatagc cgctatctac agcgtacgtt
    11641 ttggcttagg aagcaatcag gatctaatca ttatcggatg tgtgatgcct ttagttcctg
    11701 gagttcaaat tacgaacgct atccgtgatt tgctagctgg acattatgtc tcaggagttt
    11761 ctcgcggaac agaagcgatg atgactgcta cgatgatcgg ttttgcgatt gcttttattt
    11821 tccagctttt ttattaggaa aggaacacaa gtatggggac gatatttatt cagttttctt
    11881 ttagtttttt agcgactgcg gcatttgccg ttattacaaa tgtacctagg cgttcattga
    11941 tttgttgtgg tctttctggt gcttttggct ggatgatcta ctggatctgt gttcaaatag
    12001 gcggatctgc tgcttttggt tcattgcttg gttctttagg agtagcattc atcagcgatc
    12061 ttttctctaa acgtttgaaa atgcccgtaa cgattttcaa tattcccggg atggttcctc
    12121 tagtccctgg tggtttagct tatcaagcgg ttcgaaatct cgttactgaa tcctatcgag
    12181 aagcggctca ttatgcggtc caagcaatta tgattgctgg agcaatcgct ttaggtcttg
    12241 tattatcaga agtctttaac cataacatcc gtaatttcaa agtaaagcgt gacgcaatca
    12301 tgatgaaacg aaaaaaacgg ctttttaaat aaacgaagtg taacaaagaa aaggttgtga
    12361 aagagacgtt cagccttgag cgatgacaaa atatctcaca aacattgcga caagtaaccg
    12421 caggagcaat aagaagtaat tatgagtatt aaaaaaagtt ttgtaaaaat agcttctcac
    12481 atttttacat aaaattgact taatactgag aaactgactt ttgaacaccc tctatctgta
    12541 aaaaaggggc tgcgacatga tttttgtcac ggcccctctt ctttattcaa attttttcca
    12601 aaacgttcgt tgataataaa cgatccatag agcggaaagt attagaacta aaccgatcac
    12661 aggaatattc actaaccaaa atggataaaa caaagccaac attccgtata agacgataag
    12721 aataatactg atgatcaatg aacccatcat agttgcgact aaacccaaac ttcctgaacc
    12781 tctgttaaat aattggttaa tattggtcca gttcagcagc agcaaccgat aatctctagc
    12841 gaaataacgt agtgacaata agtagcagcc gaataaagaa ccaaatagca agctagggat
    12901 aaaaaacaaa ggcagctgaa aagacagtcc gcttaataat gcgatcccac cagttaaaaa
    12961 actctgcaat atccatccga atctgaactt ttcttttaaa tattggttca tagagattgg
    13021 caaagaacgg ataaacagaa aattttcttg atccaaagaa ataagattgc tgataaaaga
    13081 agtctgatta actgttaaga aagccaatgc gatccctacc aggaaaacaa caccgattaa
    13141 cttattatct aaatcagtta attttatttc gcctcctagg gcaaaagcaa gaataaaaat
    13201 gattggagtt aacaaggaag aagaaagaac ttgcataatc aaattaggtt cttttactaa
    13261 ttgagcattg taactaaata aaagctgatg cacattttgg ttctttttat gggttctttt
    13321 tattttgaac tcactgtttg aatcagtcag ttgctctgta agctttggta ctatcagctg
    13381 ttttacagca aggaaaaatc ccagagccgt gatagctagt attccccaac ccaataaacc
    13441 ttgttgagaa agtggctgac tggcagcatc atagaatggc aataatatcg aaatcggatg
    13501 ccgatctgtt aactcatttt caatagtccc cgtttgatga ttcatccaca tgattccagc
    13561 aaatgcgatc agcatcgagc tgccaagcaa gatactagaa actgtttttc tatgtttttt
    13621 aaacactgct gttcgagcca aaccaaaaac aatcaaacta gccagacaaa aaagaataat
    13681 caaaaataga gaaaacaaaa ggattgagat aatgatagta agcaaaatcc ctagatcagc
    13741 tcgccatccg gttaaaataa acatgactag aagcggaaaa acaaaaggaa tgatggtcaa
    13801 agcaactacc aaaatctttg ctgaaaaaac ctgttcttgt ccaaaaggca gaggcaaaaa
    13861 tacttgcagg tcatttcctt caaaaaagat attataaatg actgatatac tttgagttaa
    13921 acctaacata ccaaaaagtg ccacgtaata agtaaagaaa cctggcaatt taacaaagtt
    13981 catagcaaac atagcaaatc cgtaaatcag taaaaaaatc agccctgaaa aaagattttg
    14041 agacaaaaga tagatagtta atcgctttcc cttttttcct ttctctcttg ctttattcgt
    14101 gagctgtgga ttaacatata aaagattaac tcgaattaat tctaataatt gtcgcttata
    14161 catacggtcc atctcctgtc gcttgccttc cagccatttt caaataaatc ttttctagcg
    14221 tttcatcagg tgagccattc aataattcac taactgcccc ctgataaatc aattcacctt
    14281 tcttcaaaat agccagttta tcgcataact gttgtgcggt atccaataca tgtgtagaaa
    14341 aaatgactgt ttttcctttt gcggcatgag ccttcatcat ttctttcaaa tcaaatgctg
    14401 cttgaggatc aagtccttgc aaaggttcat ccaataccca aatatctgga tctggcagca
    14461 acgtgccgat caaaatcgtt ttttgacgca ttccatgtga aaaacttgcg attgtttcat
    14521 tttgatgact atacatatca aaaagcgctg tcaattctgc taaacgcttt tctttttttt
    14581 gtgtgtctaa ttcataggca gctgaaatca agtcccaata ttctccagcc gtcaattgta
    14641 aaaaaatatc tggggaatca ggcacataac cgattttttg tttgatactc aatcgatttt
    14701 ccgtcaattt cattccatct actaaaatcg ttcccgatga tggttcaata atactaacta
    14761 aacttttaat cgtagttgat tttccggcac cattatgtcc taaaaatcca aaaatttccc
    14821 cttgtcttat cgagagagac aagtctttta atgcttgttt tttcccgtaa cttttactta
    14881 cattgatgaa ttcaatcatt tctgtactcc ttttgtttgt tattactttt tattgtaccc
    14941 ttcgttattg gtggagtaaa tgtcaaaaag agtgcataac aaaaaaggat agaaacgact
    15001 aggctgctac ttgggttgtt ctcttctaca ggaaaacact cttctaacag gtaagatatg
    15061 agtctttgtt ttctttaaaa tgattcattt tctatctttt cttgcataaa attctttagt
    15121 ttatcaatac ttctctttcc catctctagt tgttctccat ttgcaaatgt tactatttcg
    15181 tttactctgc taatagatgt aatgttttca gtattaatga tataagcttt taaatcttta
    15241 cataaatact catattcgag tgatttttta tattttttaa ttgtgccgtt tacgagaatc
    15301 tcttcatctt tcaatactag gcctatttta tttttataac ctggcatgct cattagataa
    15361 aggatttcat cgtaatggat atagtgatcg ctattaccat aacggacagt tgtccacctt
    15421 tttttcgtag catgttgaac aggatagttt tctttttctt tcaataagta actttggatg
    15481 ctttttttat ttttttcata agtgaattct tttatcaaat aaccactagg cgtaatcttt
    15541 cgattaataa cagttattgc tttattcgga tgagacgtta gataaacaat tttacacttt
    15601 tcattctttt ctctaagcat ttcgcctagt tcgataccgc tataataggc gttcaaatcg
    15661 atgtctagga aaaaaatatc tgaggaatag atttcattat ttttaatgaa ttcaacaaat
    15721 tgtataacgt tcaatccctg aacgatctca aatttccaag gacttaataa aattctggat
    15781 tcttccaaaa tttctactag cattttttca aaaaccaaac tatcatccaa aataaatata
    15841 cgcgttacca taaaaagtac ctccactcga tattttacta tcaaaatcat ttcatacaac
    15901 ttttcaacat acatgttagg aataaattgt aattctcttc acaatctttt ccaacacctt
    15961 tgaaaccgat atcaaatact ttcaggatgc tgcttctaaa ataaatatca aacaaatgaa
    16021 tacatcatgc aaaaaaagcc agacaaccga cgtccttgcg tgtcagctgt ctgagctatg
    16081 tttatttatt ttgttctttt aaaaagaacg atacacatac tgatttttcg gagcagagac
    16141 tttctcagcg tttgtaacaa ctacagatgg gatttcacgc ttgaatggtt gataatagtc
    16201 tgattggatg gttccttcta ttttatacca ttcatcattt ttaaccgtta ctccttccgg
    16261 catatgcgtc aacaaaccaa agactcctga atctgccaca caatggataa tgccgaatcg
    16321 gaacaagaag atatctgtat tgctatcgtt cggtgtttgg taaacaaatc cttcatagct
    16381 gatttttttg ccaatgaatt cgctagggta attataaatt agctccataa cttctaaata
    16441 gttttcatct gtgatcttga tagtttgctt atccccatac ttttctttca actcattcat
    16501 ttggtctaag tagtctgatt tgttgaaata aatactggta tccggcttta agtattgtgt
    16561 ctgcatctcc ggatccccta ctgattcttt acttactggg aaattaaatc ctttggcttc
    16621 tacgatcgta gtgtcgagac taactgttgg aaacaacgtc cccacgatta ctggcaaagc
    16681 tagcagtaca taagcgattc cacgttgata aggttttgac aacccatggt catgatcgtg
    16741 ctcgtgtgcc ttttcttctg cttttccgtt tttgacccac aaatacagct gaactaaagc
    16801 caaaagagca gataaaatca ttgaaagaat agctaagtag cgataatgga cattgatata
    16861 ttgatcgagt ttgccagaaa cttgcaagta catcatcaat tcgaaatacc cagataaaat
    16921 caaaaaccgc agcatatttt ccctcctaaa taaataatgt gaatccaata acgctaaggg
    16981 caatcagtcc gatcagcgat aaaataaagc gtcctgtaaa atatcgtttc atcatcagta
    17041 gatttttgat atcgaccatt gggccaaaga ccaaaaaggc agctacaggt gctgtgccga
    17101 acagacttaa caaagaagat cctataaacg catctgcttc tgagcaaaga gacatcgtaa
    17161 aggccaataa cagcatgatg ataatggcta aaatctttgt tgagccgagc gttagcataa
    17221 ttctagttgg taaataagtc tgcatcgcag ctgcgattaa tccgccaatg atcaaataac
    17281 gacctgtatc aaaaaattcg tcgattgaat gtgtcaacac atgcccagtt tgatggatca
    17341 gctgattttt tggttcattc ttctcacttt gttcttcttc atggacatga tgatggtgat
    17401 tttctgctac tttagacgtg attttttctt tcaatacagc gtctttttga aaataggcaa
    17461 gccagacacc aatcacaagg gcaacaaaaa agctgcctat cacccgccag cttgccatct
    17521 gccaagaatt gccaaatgcg ataaaagtgg aaaaaatcac gattggattg atgatcggag
    17581 cagtcagcat aaaagcaaac gctgtgtgaa ctggtacgcc ttttttaaca aattgatgaa
    17641 cgatcggtac gatgccgcat tcacatgaag gaaagaaaaa tcctaagatc gaaccagtaa
    17701 aaatagagaa gatacgattt tcaggaagcc atctcttcac acgttctggg gtcaaaaata
    17761 cttgtaaggc gcctgagata agacagccta ataatacgaa aggtaatgct tcaataacga
    17821 tcgataagaa aatcgtactc atctgcaaaa ccgaatttgg aataaaagaa aacatgagtt
    17881 tcctcctttt tatttctagt tcattcgctt tgcaaatata cgcttttatt caaaaaaaac
    17941 aagttgctct gtaaattttt acacaactct tattttttac caaagcactt caattgactt
    18001 tttctgttat tcccattaaa ttaaggtctc atacatatca cttctatcat aaaagggaga
    18061 ataaaaatga aacaaaccac taacttgact gaagttcaag acatactgca acagtcatcc
    18121 gttgccgtca tttatctttc gatgcctaat tgcagtgttt gtcacgctgt tcgtccacga
    18181 ctagaggaac ttctcacaca ttatgatatt ccggcacttc atttggatgc atttgaaaca
    18241 ccagaagtag ctagtaaatt tgaagtgctg actgcgccag ttgtcctgat ttttcatcaa
    18301 ggaaaagaag tctttcggca agcacggttc atcgacttta aaaaaatccg ttatctacta
    18361 gatgaactga cagcagaaga tgattccctt tcttatgaag aaatcttccg aacaaaataa
    18421 tcgttgtcca aacagaaaaa agcgattgaa caagtgaaag ttttgccttc atttgttcaa
    18481 tcgcttttta tttttattct gctgtatttt cggaatgcgc atttgcgtca gaatgcaaga
    18541 aatagatcaa ggtttgcaat tcattcgtca aatcaacatt ttggatcaat acatctgacg
    18601 gagcattcaa tcgagcagcg gtaaagttca agattccttt gattcctgct tccgttaact
    18661 gattgactac ttcttgtgct ctttcagcgg gtatcgttaa aattgctact tcgatttgtt
    18721 ggatcttgat ttgttctgac atatcttcca ttggataaac ggggataccg tctacgatgc
    18781 gcccaacgat ttcctcattc acatcaaaag cacaactgat acgtatgcta ttactttgat
    18841 ggaatttgta ttttagtaaa gcacttccca agttccctac accgatcagc gcaacatttg
    18901 tcaattgatc gtcgtttaat gtctttgcaa aaaagtgcat aagatcttct acatcataac
    18961 catacccacg ttttcctaat tcgccaaaat aagaaaaatc tcgacggatc gttgcactat
    19021 ctacttgaac ggcttcactt aattcagttg aagacacttt tttctttcca gcattattta
    19081 aaatccttaa atagcgataa tacaaaggca gtcttttagc tgtcgccttt ggaataatat
    19141 gatctttcac gaaatgacct ccacgtattg tctaattaca tctttgattt ctccatcata
    19201 gcagtattta taggaaaaaa tcaattccat tgctcagata ttgtgaaatt ttattcttta
    19261 ttcatttatt tatcatttct gcaaatctcg cagtataatg gaatttatgg tagactacta
    19321 attgaaaaat agttttttat ttgaggagaa ttcacaaagt agaaaagagg attccatgat
    19381 attattacaa gccaatcaga ttgctcgcca ttttggtgca gaagtcttat ttgaaaacat
    19441 acatttagaa atcagtacag gcgctcgtgt cgctttagtt ggcagaaatg gcgctggaaa
    19501 atcgacttta ttaaagatca ttgctggaat tgaagcacct gatgaaggaa agatcgctaa
    19561 aaataaaaca gcgactctcg gatacctcgc tcaggacaca ggacttgatt ccaatgaaac
    19621 agtttggaac gagatgctga aagcttttga acaagttaga caaatggaag agcggatgcg
    19681 cgagctagag attttcatta gcgaaggtac gccagacaca cctgcttata gttcttattt
    19741 aaaagaatac gaccggctgc aacacgattt ttcagatcga aacggctatg gttatgaaaa
    19801 tgaaattcgt tccgtattgc atgggtttaa attcgattct tcattttatg atcagaaaat
    19861 cgatacttta tcaggcggac agcgcacacg tttagcttta gctcgcatgc ttttgcaaca
    19921 ccctgacatt ttgattctag acgaaccaac gaaccattta gatatcgaga cactttcctg
    19981 gcttgagaat tatctgcaaa gctatactgg tgcattattg attgtttccc atgaccgtta
    20041 ttttttagat aaagtagtca atgaagtcta tgaattaagc agaagaaaaa tgcgccatta
    20101 caaaggtaac tattcgaaat atctagattt gaaagcagaa cagttagcaa gtgaatggaa
    20161 ggcttatgaa aagcagcaaa cagaaatcca taaattagaa gacttcgttg ctcggaacct
    20221 tgttcgcgcc tctaccacaa aacgagcgca aagccgcaga aagacattag aaaaaatgga
    20281 ccggctggat cgtcctcaag gggatgaaaa acaagcaaac tttctattca gtatagaaaa
    20341 gccttctgga aatgtagtct tgcaaatcga agatgccgct atcggatatg ataatgtcac
    20401 cttatctgaa ccaatcaatc tagatatccg tcgtcaagaa gcgattgctc tagtaggtcc
    20461 gaatggtatc gggaaatcga cgttgctgaa atcaatcatt caccagatcc cttttatccg
    20521 tggaaaagaa acgctaggga caaatgtcac catcggctat tacgatcaag gtcaagctga
    20581 tctgcataca aacaagacga tcctagcaga attgtgggat gagcatccta ccactccaga
    20641 aaaagagatc cgaagtgctt taggtgcttt cttattttct ggcgaagatg tagaaaaacc
    20701 aatccctctg ctaagtggcg gtgaaaaagc acgggttgct ttagccaagt tagcgatgaa
    20761 caaagaaaat tttttgattt tggatgaacc aacaaaccat ttagatattg acaacaaaga
    20821 agtattagaa aatgcattga tcgattatga cggcacactg ctttttgttt cccatgaccg
    20881 atatttcatc aatcggatcg cgacaaaagt cgtcgaactc tctgaaaatg gcagcaaagt
    20941 ctatctagga gactatgatt attatttaga gaaaaagcag gaagaagaag aaatcgccga
    21001 attgttggca caagatgagc cagaatctgc tcctgctccc acgaacaaat ctgattatta
    21061 ccaaagcaaa gaacagcaaa agcttatccg tagccttcaa cgaaaaatta ctcaggttga
    21121 agaagaaatg gcgcggatcg atgaatggat cgatcagttg gaacaagaaa tggtcgcgcc
    21181 agaaaacctg gaagatcacg taaaactcaa tgagctgaac caagatttag aagctgctag
    21241 acaagatcaa gaaacaaaat tgacggaatg ggaagaacta agcttggaat tagaagaata
    21301 tgaaaattaa cgaaaaaacc aaaacagaaa ccattcatgc tgttttggtt tttctttttt
    21361 tattttatca aacaaaaatt ccatatttac ctttttcacc aataagaaga ccaattacta
    21421 gtcattctca ctaaagcttc taaataatag taatcacccc aaatacaagg tgtatttacc
    21481 ccattatttt tgggcttatt ataaacagac tgtgttaaaa agccatcttc ttcttccgtt
    21541 gtagcatatc tttctttcaa ttgtcgcata attttccaaa cagcagactg gtataagttc
    21601 ttttctgttt tgtctaatag acctgattct attaattcta ataatccaca aaccatgatc
    21661 accatactag atgtatcttt ttcttctctg ctagaatcat caaagatcaa atcccaataa
    21721 caaatggtat cttctggcaa ccgattcata aaataattgg ctaatatttt gcttaaatca
    21781 aaatattttt gttctttcaa ataacgataa cttaatgcaa aaccgtaaat cccccatgct
    21841 tggcctctag cccaacagga attatcacta taaccttgat gcgtacttcc atatcttggt
    21901 tttccatctt tgacatccat ataaaatgta tgataagttg aaccatcttc tcttactaaa
    21961 taatctgctg cattttgaat atgagcctga gcagcttttt tatatttttg atttccagtt
    22021 tcttcactcg cccaatacaa taatggaaga ttcatgcaac aatccatgat cattctacct
    22081 tgttgtgaag gatcactagg atctccccaa gcttgtataa ctcctgcctt ctcccaaaaa
    22141 cgctgaagta atgtttctgc agcatcaatt gaagcttcct tcatttttcg atttcccgtt
    22201 attttataat ctgctacggt tgataaagaa tacaaaaaac caagatcgtg atgattagtg
    22261 ataatttgac agtcaatcct gtggataaaa tctatatctg ctttttcagc tgtttgttga
    22321 aataaaggat cacccgtctt ctcaaataac aaccaattaa ttcctgtcca aaatccttct
    22381 gtccaaccaa tattgtctct taatggataa cgtcctttta taggacactc gcttgggaat
    22441 tgatactgac tgttactgat acgtttgatt aacctctccg tgtgtctgcg acaacgctcg
    22501 atctcattat tccattcttt ttccattaat tctttataac attcatttat ccatttttct
    22561 ggatgtatta tctcttcaaa catcacttta tcaagcattt ccccaccagc ctttagcata
    22621 attttagtct ttttttattg tttttatttt ggatagttag cccggttgtc ccatcaaaat
    22681 caattttggg acgattgttc catacttcta aactataatc ccgatcttga tgagcaacca
    22741 ctcctgttcc gagccaatgg gttccttttc caaatgtacc ctctaatcca ggaataaaag
    22801 tgttttccca tgtcatcaag tttgtattgg gcaaacccat aatagctgtg gattttcgtt
    22861 taatagtatc gtcacttaaa cagataatac ctgaaaagcc agcttcactc accctatagt
    22921 tttccttgtc ttcttctatg attattcctt ctttctcagg agaacattca atagcaaacc
    22981 ctgtctcata tagaacatat tctgtatcta attctacttt gtgtacgcga atctgccagc
    23041 cttcaaaagg aataagccaa gttctgattt ttgcctgtaa agtaggttcc catgtagagg
    23101 caagtacctc tttcttacat acaatgtctc gtacattatt tcgaacgatg aactgtccat
    23161 aggttttgat gctctcattc ttaaaactgg tcgtgatata tgtgtccgct cgctgaatcc
    23221 ctagcattga atccattgcc atttctgctt tcaattgatt cgctcgcggt atcgaaaaac
    23281 caaattgact agaataagca aattttaaat atttttcatt ggtcaatgta tggaaatttg
    23341 gccctaattg tcccgcattc aaaaaaaatg tatgtccatt atcatgttgt atgagcaaat
    23401 tggcttctga aagaagttta gttccttcac gaataggcat aggcatttct ttagccgtcc
    23461 aatactcatg gtcttcaggt agcgccaaca ataaaaaaat cttattcagc cataatggag
    23521 ataacgtact attatagggt tcagtcaatg tcaattgagg gtaggtataa ccaatattca
    23581 ggataccttt ttcatcaaat atttcttttt gcatccacca tcttatattc cgattgacta
    23641 accccttgat ttcacctaat ttaaaaggca aaagatcggc ccacaacata gctgaccaaa
    23701 agcttgaaac tgcaaaacga taaatcatgc ttcgaccaaa aggcacattt gcaccatctt
    23761 ccgcaaaaaa atgaatatag tctctagaaa aatcaatagc tcggttctta tatatctggc
    23821 taatgggctt ttctggttct agtacgctat aaatcaaacc ataataatga aatgcaaaag
    23881 gattataata atcttggcga cctcttgaac tgtctcgata ccagccattt tgaagataac
    23941 aattttctat attatcaaat gcttctttca gtgctgattc tttaactgga taaccaaatt
    24001 tttggataat tgttccgaca attatcttaa aaaattgcca attaccatct gcacattcat
    24061 attcaaaaat ttgcgagaac caatgaataa tctggctttt ttctcctgta tctaattttt
    24121 tccataataa ttgttcatga tgatataacg ctaataacat tgcgggcatt tctaccatac
    24181 gctggtctct ttcatgtatt tctccccaat aatcgggatg ggaaggatct gttccagctt
    24241 ttattcctga tagaattaat ttcaaccatc gttcatctaa ttggtcaatt gcgggccccg
    24301 ctccccataa aacccgagag aatccttcca ttcctgcaat tttatttcca tatcctaccc
    24361 cttgatgtat ataatcaatt tgtgcgccac ttgctcgata aaacggctgg agtggttgat
    24421 ttatcttttt aaataagtca aagtaatcct gtctggtcct taatagtggt actggatgtt
    24481 tcattgtatt ttctcctctt tttactacca aatagctaat tccgactgtt ctaatcgaag
    24541 taagccttca ataaaaaaat aatcagaata gatcagtggc acattataag tcagttctct
    24601 atggtatgct tctgctccgc ctccaatgat cccatcttca tccatattcc aatttgcata
    24661 gtgcttttct gtcttttgga gtatattgat agcagcttca tgatacattt ttgatcgtac
    24721 agaggaaaca tatcctgcta attccagaag accgcatgca gcgcatactc cagcactggt
    24781 atcaatattc gaatctttta cagcaaaatc aatgagagga atataaccag ttttttcgat
    24841 tttctgaata aaatttactg ctatcttttc tgctatagct agatagtacg gattttttgt
    24901 gtaacgataa cttaacgcga atccatataa agcccatgca tttcctctgc tccaacaaga
    24961 attctcattg tatccttgcc cgccaagtaa ccgaatatat ttccctgatt ctgcatcaaa
    25021 ttctgcgata tgcccggttg atccatcttt cctcactaga tacttagctg ttgtatctgc
    25081 atgctgccga gcaattttag agaacctcgg atcaccagtt tccctcgaag cccaatacag
    25141 taatggtaaa ttcatcatac tatcaataat catccaacca ggtttatggt cattccatgc
    25201 tactaaatag ttccctgaaa tattatagcg tccagcaagt accgtagctg catgtaaccc
    25261 tagttgtcga ctatgtttgt tttgagactg ttgataatgt gcaatagccg atggtaagaa
    25321 taaaaaacct acatcatgat gaacgtctga aaaatggtac agggcagatt ctaataattg
    25381 ttcttgttgt attgctgcct ctttgaactt ttctcgtttt gtcttgtgaa agagctgcca
    25441 taaaatacca ctccaaaaac cattggtcca ccagtcgatt cctctgtcct ttattacgtc
    25501 tgtatatttt ccgttgtaag aaatatatgg aattttattc cccattctgt ctaattccgc
    25561 atctatcttt tcagaagcta cattcaaaat ttttcttgac cattccttcg tctgttcatt
    25621 catggatatc ccgccattct tttaattttt atgaatgtgg agttgctcct agaacgaact
    25681 agatggttaa cattcgttat tttttttact tatttgcagc tccaatgtca ttctccttaa
    25741 atttagactg cgcccacaca taaatcaaga ccattgggat cactgaagtt gctaaaatta
    25801 gcataattgc gccataatta attggctcac ctgtactaga aaccgtcata tttttgataa
    25861 ttaagggaac cgtatattta tctttatctg aaagcatgac taatggaaat agatattgat
    25921 tccaacttcc cataaagata agtaaaccac tagtaataat cgtaggtgat aaaatcggta
    25981 cagcgatttt cgtaaaaatc acccactcat tggcaccatc gattctggca gcctccatca
    26041 gtgctgtagg aaattgactg ctatattgtc gcatcataaa cactgaagtt gtactggcaa
    26101 tcgaagggat gatcacacct gcataagtat tcgataatcc taaacgactc ataatgtaaa
    26161 ataaaggaat caatgtggta aaaaaaggca ccatcctaga tagcataact gtattgaaca
    26221 acagtttatt ccccataaaa cgatactttg ctaatgcata acccgccatt gtagaactgg
    26281 ctgtagctga aactgtactg attacagcaa taacaatcga attccaaata atcaagggat
    26341 aattatatct cgccatgatg gcttgccagt tttttaatag catatcccca aacttgaaat
    26401 tgattccgcc acttaaaatt tcttgattac tttgcgttga agctacaatc atatataaat
    26461 atggcatcaa aaatattaag gcaccaaaca caataatgac gtacgtaaaa attctgcttt
    26521 gtatcttttg tttagtcatt tttatcacct ccgaatttaa attgaatagc cgataatata
    26581 acagatacaa acaccatcgt ccaggcaata gcagaggctt ttccaaaatc aaccatttca
    26641 aaacttgttt tatataaatt gactcctacg accaaagctg aattttctgg tccattggaa
    26701 gtcccaaaga atatatttgg gatattgaaa ttacccaagc cattgatagt ggctaaaact
    26761 gtggccatta aaatgattgg ctttagcatg gggatcgtta ataaaaagaa ttgccgaaat
    26821 ttcgatgctc catctatttc agcactttcg tatatctctt tagaaatccc ttgaagacca
    26881 gctaaaaata aaatagtgtt atatcctaca ctaagccaaa tcatcgtgat gatcattgat
    26941 attcgtatcc aaaaaggatt tgttaaccac tgtacaccgt taattcctag cgcattcaaa
    27001 aatccattga ataacccagt cggattgaaa aaagtcatga atacggaagc tacagccacc
    27061 gttgatgtaa tggttggaat ataatagaca gttctaaaaa atccttttcc ttttaactgt
    27121 gctgaattca ataaaacagc aaagtaaata gctaatagca tcgttattgg aattgatcct
    27181 gccatgataa tcaaaacatt cgtgtaagat ttaataaaca atggatctcg gaagatagct
    27241 agataattgt caaatccaac aaattcaaat gagtagccaa ttttcataaa actaaaagca
    27301 aacgagataa tgatgggaat caaaatcgtc acaataaaga aaataacaaa aggtgtgacc
    27361 aatccataag cacttttttt atgagacgta tctgttgctt ttttcttgct gttctttatt
    27421 gtcttgcttg gtaacgaaga ttgcatcatc gttaagtcct cctaatattt tttaatcacc
    27481 agttaatttt acgccgtact tatgagcaaa attttctgct tcttttagat atgaattttc
    27541 aaaatcacct gtttgccaat agttatatgc agcggtagtc aaataagacg tagcatctga
    27601 ataagtggct ggtaaaacag tatttgatgt attttcattg attttattca atagttcata
    27661 gtatttttgt cctccttagt agtcaaactt tttctcagct gcttctgttt gataggccaa
    27721 tgagttagat gtagccacgc ccagctccag tgcgttggct aagcattctt catctgtcag
    27781 cataaatgta agaaattgtt gtgccacttg tggatttttg gcatctttag ggacataaaa
    27841 acttgatcct cctgatactg caccttttcc tggattttct tttgaaaaag gaatcagtgg
    27901 agccatgcgc catttgtcag atgcatcagg aaaattcaaa gacatattcg tagcatacca
    27961 gccgccagca acaaacattg cagattcttg aaatgctttc tcagcatctt gtgcaccgta
    28021 gaaatgtaca atatctgagt cgatcatttc tttgattaac tttgcagcat gtttcgcttc
    28081 tttagtattc agacggatat ttccttcttc atcaagcaaa gattgattct gctgggctag
    28141 catgttgata aacaattctt ggtccccaga ttctggcaag gcaattccaa aactaccagt
    28201 tttttctttt aatgcttttg ccacctggat atattcttcc caagaactga tttcttcaaa
    28261 atctacacct atttcagcaa atttttttgg ttgataataa caaagtgctg gggtaaaatc
    28321 actagcccaa ggaataatcg tttcattact cgtttgttga cgcaaaatat tcaatttttg
    28381 atcataaaac tgatcgccat atttgtcata aaatccatat tcatcagcac tataaaaagc
    28441 atcttgaaat ttttccagca cacctgctgc tgaagtgtct gccatggaga taatatccgg
    28501 catatcttcg tgtgttacca attttggggt gatcatttgt actgttgctg ttcccgaagc
    28561 tacattcaca atttttaagt caatatttgc tccagttttg cggttataga tttttgcagc
    28621 attttcaaca tagtttgtca gtttgccgtt tgcgacatat acttctaatg tagtggcttt
    28681 ttttatcatt ggatctgcga tgtttgctgt tacttcttcg ttagtttttc cacatgcact
    28741 taagctgaat aatagggtaa tgtttagcaa agctatcacc aatttgtatc tttttttcat
    28801 gtctatccct tctttctttt caagttctta tataaaacgc tttcacttat gtatattaa
//
LOCUS       DACCVZ010000029        28075 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.029, whole genome shotgun sequence.
ACCESSION   DACCVZ010000029 DACCVZ010000000
VERSION     DACCVZ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28075
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.029"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(190..1089)
                     /locus_tag="IVW63_001321"
     CDS             complement(190..1089)
                     /locus_tag="IVW63_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAP7859603.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            complement(1099..1455)
                     /locus_tag="IVW63_001322"
     CDS             complement(1099..1455)
                     /locus_tag="IVW63_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP7859604.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            1810..2106
                     /locus_tag="IVW63_001323"
     CDS             1810..2106
                     /locus_tag="IVW63_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HAP7859605.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            complement(2750..3703)
                     /locus_tag="IVW63_001324"
     CDS             complement(2750..3703)
                     /locus_tag="IVW63_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7859606.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(3726..4481)
                     /locus_tag="IVW63_001325"
     CDS             complement(3726..4481)
                     /locus_tag="IVW63_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7859607.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            complement(4478..5437)
                     /locus_tag="IVW63_001326"
     CDS             complement(4478..5437)
                     /locus_tag="IVW63_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAP7859608.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            complement(5430..6380)
                     /locus_tag="IVW63_001327"
     CDS             complement(5430..6380)
                     /locus_tag="IVW63_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAP7859609.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            6530..6982
                     /locus_tag="IVW63_001328"
     CDS             6530..6982
                     /locus_tag="IVW63_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HAP7859610.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            complement(7071..9338)
                     /gene="gshAB"
                     /locus_tag="IVW63_001329"
     CDS             complement(7071..9338)
                     /gene="gshAB"
                     /locus_tag="IVW63_001329"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HAP7859611.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(9525..10523)
                     /gene="ftsY"
                     /locus_tag="IVW63_001330"
     CDS             complement(9525..10523)
                     /gene="ftsY"
                     /locus_tag="IVW63_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAP7859612.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            complement(10534..11343)
                     /locus_tag="IVW63_001331"
     CDS             complement(10534..11343)
                     /locus_tag="IVW63_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7859613.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            complement(11352..14933)
                     /gene="smc"
                     /locus_tag="IVW63_001332"
     CDS             complement(11352..14933)
                     /gene="smc"
                     /locus_tag="IVW63_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAP7859614.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            complement(14953..15639)
                     /locus_tag="IVW63_001333"
     CDS             complement(14953..15639)
                     /locus_tag="IVW63_001333"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAP7859615.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            complement(15987..17768)
                     /locus_tag="IVW63_001334"
     CDS             complement(15987..17768)
                     /locus_tag="IVW63_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7859616.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            complement(17794..18708)
                     /locus_tag="IVW63_001335"
     CDS             complement(17794..18708)
                     /locus_tag="IVW63_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7859617.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            complement(18735..19697)
                     /locus_tag="IVW63_001336"
     CDS             complement(18735..19697)
                     /locus_tag="IVW63_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7859618.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            complement(19697..20641)
                     /locus_tag="IVW63_001337"
     CDS             complement(19697..20641)
                     /locus_tag="IVW63_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7859619.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            complement(20642..21646)
                     /locus_tag="IVW63_001338"
     CDS             complement(20642..21646)
                     /locus_tag="IVW63_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7859620.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            complement(21914..22156)
                     /gene="acpP"
                     /locus_tag="IVW63_001339"
     CDS             complement(21914..22156)
                     /gene="acpP"
                     /locus_tag="IVW63_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAP7859621.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            complement(22278..23279)
                     /gene="plsX"
                     /locus_tag="IVW63_001340"
     CDS             complement(22278..23279)
                     /gene="plsX"
                     /locus_tag="IVW63_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAP7859622.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            complement(23328..25364)
                     /gene="recG"
                     /locus_tag="IVW63_001341"
     CDS             complement(23328..25364)
                     /gene="recG"
                     /locus_tag="IVW63_001341"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAP7859623.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            complement(25481..27163)
                     /locus_tag="IVW63_001342"
     CDS             complement(25481..27163)
                     /locus_tag="IVW63_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAP7859624.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            complement(27215..27577)
                     /locus_tag="IVW63_001343"
     CDS             complement(27215..27577)
                     /locus_tag="IVW63_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP7859625.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            27847..28035
                     /locus_tag="IVW63_001344"
     CDS             27847..28035
                     /locus_tag="IVW63_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAP7859626.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
BASE COUNT         7765 a         6079 c         4949 g         9282 t
ORIGIN      
        1 gattatcgtt caaaaaaaga atacacgctt gcatctagta ctctgcgagt tacaaatcat
       61 ccgatcaaat aaacattcgc tgattatttt ccgcaaaaaa agcagcatat ccacgataaa
      121 tggatctact gctcttactt atccttatgt tttacaaggt attttctttt acacattact
      181 aatgctgtct caatacggaa cgattgtcat cgcttgttca aattcctctt gcaaatgttg
      241 tgtttgatag gcctgaaaag ctgggtgatg ggcacgcaag aggacacgta atttcatagg
      301 atcatagctg tctagcaact gttctttcaa gacaaaatct cgggtcagct gccattcata
      361 ataataacca aaaggtctgc agctgtaaat cgtgtgaccg atggatttat cttcaaagcg
      421 acgatgcgta tggccaaaaa ctacttgttt gatatttgaa taacggtcaa gtaattctcc
      481 gaatgattct gatcctaaaa atgcatttaa tttgttccaa cgctcataag gagcagattg
      541 atacatgata aatgcccgtt taggaacgaa atgagtggat aaaatcacct caagtttttt
      601 tgcttccagc tggtctagca aattttttgc agctgcaagc atttctgcat tgacctcgag
      661 atctgttttc ccacgctgga tgaaccgatc ataccaatac aaacgcttca ttcgtacgat
      721 tgcctcgtaa tctttcaatt cggaaaactg atagtcgtac cagccattca tccctaaaag
      781 aacggtctgc tcatttaaag caatataccg ttcatttaaa aaatgtgggt ctggaaaatg
      841 gtccatcatc tgttcattgg gcacatctgc caactcgtga ttgccgaaat gaaatgtcgt
      901 agataatcct ttattgacga aaaattcgac aacagctagg caacggtcta ctttattagc
      961 cgtatctccg gctagatgaa gccgagtgat cttgtgcttt tgcaaaactt gccaaagctg
     1021 catcagctct gattcgccga atttattgat gtccacatgt aggtcgctga tgatcgccaa
     1081 ttttcccatt ttatccctct agtcttttcg aacaacttgc aagttgcctt ttctcaagcc
     1141 gcttggtcct tttaattgta aactattata agttggttct aaagcaagtg tggatggatc
     1201 atccatgtaa agtattgcac tgtctttgat tttgattggt ccaactggtg tatcagccac
     1261 tacagaataa agacttagat ctgtttgtgt atcttttttg acaatgatca atcgaaatgc
     1321 cgtatccaat tggcaactga cttggctttc tgcaaatgga ccgtcaccgt tttcgatatc
     1381 taataaaagt tgatcgtctg cttctaattt attcttcaat acttcttgtg cttcttttgt
     1441 cacttctaat ttcatctgta tcacctcatg tcatagaata atcactttat tcatcagatg
     1501 caactaattt gtctggttct gactgttctc aatttattgg aaagtaagtc attcgtttat
     1561 tatgatttct cttatcacaa aagagacaac tttccctttt cttcgttcag tttcttgaac
     1621 ggaaaaagac ccaaaaagca acctgttatt tgtttaacct tattcctttc ttaaataaca
     1681 aaaaatacta taaaaaataa aaaaccttta acaactattg gaaaaagaat tactttttgt
     1741 tcacggatta ttaacaactc ttcggtagag taaacttatc aaataaaaga cttctttgga
     1801 ggaatcacta tgaaggaata tataaaaaac atctatttta tcgaagaaac acaaaatatc
     1861 gagggttctt atattgaagt aaaaacactc tttgtcaatg aagataaaac caaagcattg
     1921 gatatttata aaaaattagc ttcaaaaaaa acgaatagtt ttggattgat attaagcgag
     1981 tataaaatca aagcagaaga gagttatttc tatcaattac taaaacggtg gagtaagctt
     2041 cccgccgatt tttatcgaaa aatgcagatc atcaactatc aaccgcttgc tgagacacat
     2101 gcctaaatag aggttgtgaa atcagtgctt tgagctaata ccgaaggtca gctgattgaa
     2161 cattgtttag aagagattgt gacaactgcg atttgctttg agtaataaga acgctggaca
     2221 gaaaatagct tctcatattt tctagtctag tgggcttatt gccgagaagc agcagatgga
     2281 acatcgttta gaagagattg tgacaactgc gatttgtttt gagtaataag aacgctggac
     2341 agaaaatagc ttctcatatt ttctagtcta gtggacttat tgccgagaag cagcagatgg
     2401 aacatcgttt aaagaagaga tcggtacaaa ataaaaatat ctaaatttaa gttttatcta
     2461 agtttcgctt tgtacctttg attcaaatca aaggaggcga tcttgatgct gaaaaaatgg
     2521 atcacactat tttttgccac tccccattct agaatcaacc cgtatgatgt agataatgaa
     2581 ttcacgttga aaaaagattt ctcaaataaa taaaaaccat ccgtaaaatc atcaatacga
     2641 ttttacggat ggtttttgat aacttctttg aggataggct cttgctattt aagaatgtaa
     2701 gaaacattat tgttacatag tatgagagtt taatcctctg ttatttatgc tatttaaatg
     2761 cttgattcac atcttcgatc atcagtttca ttgattctaa accgcccccg cttaaatacc
     2821 agacatctgg ttcaagggag atgatctgct gatttttacc agcattcgtt tgtgctacca
     2881 gttcattggc agaaatatca tctttgctgt cgtctccacc aatagctttt gttctgtcta
     2941 ctacaaataa gatatccgga tttttttcca gcacatattc ataagaaaca ctttgaccgt
     3001 gagtggatgc ttcgatttga tcatctgctt gttcaaagcc aaataaatca tggatgaaac
     3061 cgaatctaga accagatccg taggctgata attgcccttc attcacaagt gtgactagtg
     3121 cttttttgtc agtagcttct gctttctttt tcgtctgatc gattgcacta gataattcct
     3181 ctaattgagt tttagcttct tcttgcttac caaagatctc ccctaaagca gtgacatttt
     3241 gctggaaaga ttcccatgga tttttcgcat ctaaagaaag gaaaatggtc ggagcaattt
     3301 gacttagatc tttttgaaaa tctctttgtc ggccagaaat gatgattaga tctggctgaa
     3361 gctgattaat tttttctaag tctggttctt ttattccacc tgctgattct acttttttat
     3421 aggatgaaag atactcagga aggctgcttg tagctgctcc aactacctta tctccaacac
     3481 caagagcatc catcgtatct aaagaaccat tgtcgaatac gacgactttt tctggattat
     3541 ttggcacctc gatttggtct ccattactat ctgttatcgt caatgtagtt tcagtttgtg
     3601 tgctgctttt ttttgtgtct gcctgactgg tgttgttgct atttccacat gctgctaaac
     3661 caaatgatgc tagaatcaag atacctacta ctaatttttt catctcttct ctcctaatgt
     3721 tagttttaga aataaagaca gaatctgcgg ccttcaatct cacaaatccg tatgtccatt
     3781 tcgtataatt catccaatac atcttttttt atcatttctt gggtcgttcc ttgcgtaaat
     3841 aactgtccat ctttcattgc aacaatttcg tctgcataac ttgcagcaaa gttgatatca
     3901 tgaagaacaa taacaattgt tttcccgatt tcttgtacta aattttttaa aatctgcatg
     3961 atttgaaccg caaaattcat atctagattg ttcaaaggtt catccagtaa aatataatcc
     4021 gtgtcttgcg ctagcaccat tgcaatatac gcacgttgga gttgaccgcc tgaaagagtg
     4081 tcaatcgatt gatccgctat ttcttctaac ccaaggtgtt ccagtgattc ctgaacgatt
     4141 tcctcgtctt ttgtcgtcaa ttttcctttc gtataaggaa atcgtccaaa ttctactaat
     4201 tctttcacgg tgatttggac atttatttca ttcgattgtc gtaggatcga taattttttg
     4261 gctaattcat tggatttcca agcctttact tcgttatggt ctaaatagat ttcacctgta
     4321 tcttttggta tcaaacgact gatcatcgac aacaccgttg actttccagc accatttgga
     4381 ccgataaaag cagtcaactt cttttcagga atcgttaact gtacatcttt aaccactgat
     4441 tttccatggt acagtttatt gaccttttgt aaatcaatca taggatactc ttcctttcgc
     4501 gaatcaattt tgtgacaaaa taaattcctc cgacaaattc aacgacgaca ctcactgttg
     4561 tattccagcc gaaaatctgc tctactgcga gctgtcctcc tgtcagaaac agcatagcta
     4621 ccagaaagct tccgataaat agctgaccat gacgataagt agaaaagaca cgataactga
     4681 tatttgcgac aataaaccct aaaaaagtaa ctggacccac aagagccgtt gatgtccctg
     4741 tcaaaagact gacacaacat aaaatcaaaa attcaaaacg atctgtgtct atcccgaggt
     4801 ttactgcttg ttcatttccg agatggaaaa cgtctagcac atgtcgatat cgaaataaca
     4861 ggtaccagca gccgataatg atcaaagaag caggcaaaag atactgactc tggatattgc
     4921 caaagcttgc aaataatctg ccttgaagca aatcatattc attcggatcc atgatgactt
     4981 gtaaaaaggt actgacacta ccaaaaagcg tacctaaaat catccctgac atcagtaata
     5041 aaaaaagatt cgctctcatt tttttcaaaa gaaagaaaaa taacaataga ctcagcccga
     5101 ccatcagccc aacgttcaat aagaaaaaaa ctgtacctgt ctgctgaagc atcgtcactc
     5161 ctccgataaa gaagaaaagg accgtttgga caaggacata taacgactca agtcccaata
     5221 ctgaaggagt caaaaactgg ttatgcgtaa ttgtctgaaa gctgattgtg gcactgctga
     5281 cagctagcga gacaaggata aatgcaaaaa ttttcttact cctcaatgca catgcaaaat
     5341 gccagtttcc atatgtatgg atcgtcaagt acattcctgt aacaaataaa acaagaacaa
     5401 gcataccaat aaaaatagat ggcttttttt taagcatatc gtcgtcccct tatcagaaga
     5461 taaaggaaga tagccccacc gatgattcca acgatcacac tgactggtat ttcataagga
     5521 aaaatcaaca cgcgagcgac aagatcgcaa aatactaaga acaaactacc tgctaaagca
     5581 gttacgccaa ttgttttgtg cacttgatct ccatatattc tagagacaag attcggaatg
     5641 atcactccga taaaaggaat gcttcctacc atgatcaaca tgactgcact agccaatgat
     5701 actaagccaa tgcctaaaaa ctgcatcttc tggtaatcta ttcccagatt tactgcaaac
     5761 gattcgccca gaccaatgat cgtaaatcgg taagcaaata gccaaaccaa gagcaacaat
     5821 ggaacaacag catacaataa ctcataattt cctcgtatca cagtcgcaaa attcccttga
     5881 agccatgaag tcatattttg taccaactgg aattgataag caaaaaaagt agcaactgaa
     5941 ccaatgatat tccctaacat gactccaatc aacggaagca tcaattgatt tttctggagg
     6001 aacaatcgcg taagggataa aaaaagcaat gttcctgcaa aagcaaagca aaatgctgtc
     6061 aaggatcgga caatcaagga tgcaccaggt aggaaaatca tagccactaa aatacctaaa
     6121 cgcgcactat ccatcgtgcc cgcagtcgtt ggtgaaacaa atttattttg ggtcaaatgt
     6181 tgcatgatca acccacaaat actactggtc gctcccacaa ggatcaaaca aatcgttcgt
     6241 ggcaaacgag tcactagcaa gatttgtaag ctttgcccat ctaactggag cagttctgac
     6301 aattgtacat tcgatactcc gatgaacaat gaaatactac ttaaaataac taataatgct
     6361 actagtcgtc cgtagcgcat ccaatccacc tttctaattg agaatgattt tcattcttat
     6421 tttaagtgaa tcgttgaaca aaagcaaccg ctttttcata tgttttaggt attattggga
     6481 atatgctata atcgtaagaa agacaaagag aagaaggagg gtatttttta tggcacaaga
     6541 tgatgtaaaa agccatttgg ataagggact ttatggtaca cctttagtga accctgaaga
     6601 acagcataaa tatttaggga cattcaggga acgctgctat cttagtatga ctgttgctga
     6661 aatgatccaa ccaaaaaaca aagaaaactt tttaaaagaa ctcaaaaaac atccagatgc
     6721 ttccatactc ttgaatgggg ctctacccct ttctgtccaa aaccaatata tccagctagc
     6781 aacgaaaaac aatagccgtt tcactgtagt caacgattac gtcactgcaa atcctgagga
     6841 attcggattg ctcttaacag caaaagaagc agtaaatgaa cctgtgattg atatcgaaaa
     6901 aaaataccca gaagaaaact cttcgccagc tgaaaaagaa aaaccaaaaa agaaaaaaag
     6961 cttctgggat cgtttatttt aaaacgaaaa aacacataaa tttttacatg caaaaaaagc
     7021 ttttgatcag attgacatca aataggacaa tctgtcaaaa gctttttctt ttaaaatact
     7081 tcaggatata acaatttcaa tacattcatc gtcaatcttc tgccttttcc tgcaaaagga
     7141 taaacatgca tatgcatggc tggattgaaa tttgcttcga tgatcccata tgctttttta
     7201 tcagttgtag gatcgatttc tttatctggt ataatcaaat cgataccact aatcttagct
     7261 cctagtgctt ctaccgcaga aacggcgatt tttttgtaag cttcagaaaa ttcatcagtc
     7321 atatcgatcg aatcaccacc tgtactgata tttgagttct cccttagata aacaatttga
     7381 ttggcttggg gaactgattc gatcgtcaac ccttgttctt tcaacatcaa ttgttctaat
     7441 tcacctaatt ggatcaattc taaaggtgca cgatgattcg ttccacgcaa agggtcacta
     7501 tttttttctt caacaagttc tttcactgtt cggatactgt caccaataac attagcaggg
     7561 actcgcaaca tgatggcttg gacttctccg tcgatcacaa agaaacgata ttccgttccc
     7621 ggcataaatt cttctactaa aaccgaactg tcttcacgaa aagcaatggc taaacctgct
     7681 tgataatctt ccagactagc tccttccttg aaaatcgtga tacctaaccc gtaattggtt
     7741 gatttaggtt tgatcacaaa tgcctgctcg gcaaatctcg gataagcttt taccgcttct
     7801 tccatggatg aaaattctgc gcctcctggt acccggaacc cagcttcttt taagactttt
     7861 ttcgttactg ttttgttttc catgataagt gggacgatat agctgtcctt acttgtcatg
     7921 tttgcatttt tcacatattc tacatggtct tggaattgca gacgcaaaaa ttgatccgac
     7981 tcatctaata ctttgacttg gacacctttt tggatggcat cgaacataaa tatctgagta
     8041 gaaagttcca tttcgcgaaa accggccaac tgatagggac gttcatggct ttctttataa
     8101 tattgatgtc ccaatgccac agcaacttct tgctgactcg atagctgtgc ttcttgatag
     8161 agtttcgctg ctaacgtttg ttcaggatga tccatttgag tcaatgcttc ctctactaaa
     8221 taaagagaat ccaaccaatc caattcaacc agcatttgct tcattccttc aagaatttct
     8281 ctaccttctt gatgaaattc tgtttgatct gatggttgtt ctagtgctac tttgttattt
     8341 cgagtcgtac cttctgctac ccattggtca cagtcttctt tttcttctgt ccataacatg
     8401 tacatcagga ataattgtaa gaaccgaact tgctctggat tgatacccaa tcttgcataa
     8461 ggattcaaat cgatattccg caattcaata taacgaacac ctgttgttgc taaatctgcg
     8521 actttctttc cgcctcggaa acgaagcggt gtataaaatt ctttctcctc cgaaagtttc
     8581 ccttcttcga tcattcgctc gatatctgct aaatactgtt tcatagaagc ataggaaact
     8641 ttcacatttg gatgattcgt atagcccagc gcactgttgc gaatactgcg aacaggttct
     8701 tgcggatgtg attcatctaa aaagtagttc ttctcactca ttggtgaagc accgaataaa
     8761 taagtgatca tccagcgata gcgcataaag tttctcgctg ttttcaaata aagttctgtt
     8821 ttgaattcgg aaaaatcttg aaattcttcc tgatggctga acaatgttct tagcaactca
     8881 tcgccaaatt caaaattgaa atgaataccg cttaccatct gttttcgctt cccgtatttt
     8941 tttgctaaat aacgtcgata caagacatct tcgaaatttt ttaattttgc aataatgatc
     9001 tcttcgtctt tttccggtaa ggcaggtggc atacttaatg gccagatcat ctcttctttc
     9061 ggtatagaac gagcagtcac atcataaaca gcagcgagat actgaaataa ttcgggaata
     9121 gaatcggtaa caggggtgat catctctgtt tgtgtttcgc taaaatctgt ttggatatag
     9181 gggtgatagg atcgatcgcc aaagattgct ggatgatcgg tttttgctag atttcctgca
     9241 agatcaaccc gctgtccttc ccgttctata ccaaatcgag cttggtcgat aaaagggcgc
     9301 gcattgacat gcaataataa ttgcttaaaa ttcatcatta agtgacctcc aattcatatg
     9361 aatctaatta taatcaaaaa gtctaagaaa aagaacgaaa ttgtttgaga accgcttaca
     9421 aataagtata aaaatgaagg catcaaaaac acagctatgt taaaaacaat cattcaaaca
     9481 aggagctgca acttttgtca cagctcctgc tttttagaca tgggttattc ttcttttagt
     9541 aatcctttga acaatccaac gacaaaatca tttggatcaa acggctccaa gtcatcgatt
     9601 ccttcaccaa gaccgaccaa tttcactggt aaatgcaatt cattacggat agcaagtacg
     9661 ataccgccct ttgctgtacc atctaatttt gtcaaaacaa gaccggtcac atctgttgtt
     9721 tctttgaatt gttttgcttg aaccatcgcg ttttgaccag tggttgcatc taatacaaga
     9781 agtgtttctt ggggtgcttc tggtaattcc cgctggatta ctcgttttat tttttctaat
     9841 tcgttcatca agttcacttt attttgcagt cggcctgcag tatcaactag taaaacatct
     9901 gcctgctctg tctttgctct ttccaaagca tcgaatacga cagctgctgg atcgcctcct
     9961 gcattgccac gaacaacttc aacaccagcg cgttcgcccc agacaactaa ctggtcgatt
    10021 gctccagcgc ggaaggtatc tgctgctgcc atcaatactt ttttaccttc gtttttgaac
    10081 tgatgggcaa gtttaccaat acttgttgtt ttccctacac cattaacacc gacaaacaaa
    10141 ataactgtta gtccgtcttc ttggatattt agttcattta cttcattgat tccttccgct
    10201 tcatagagat ccacaagttt ctcgatgatc gcattttgga cttctgccga ttttttcgca
    10261 tttctgagtt tcacttcttg acgtaatgct tcggtgattc gtatcgctgt ttcaaaacct
    10321 acatctgcac cgataagtgt ttcttctaat tcttcaaaaa agtcttcatc gactgttcga
    10381 aaattggcaa acaactcatt catccgttca ccaaatgttt tacgcgtctt ttctaaaccc
    10441 ttgtcgtact tctcctgtac ttcaacttct tctgttttct cttcgccagt aaaagcacgc
    10501 ttgattttat caaaaaatcc catttgactc cccctactct aatacaaatt tttggatcac
    10561 tttggctacg ccattttctt cattgctggc tgtcacgaaa tctgctgctt ctttgacgaa
    10621 aggcacagca ttctccatcg ctacgcctag tccagcatat tggatcatcg gtaaatcatt
    10681 ttcctcatca ccgatcgcca tgatttcttc ttgtttcaaa ccaagatctt ttgccaataa
    10741 agaaatacca taagcttttg taacaccttt tggcataaat tccaaaagca tacttcttgt
    10801 tttgatgatc tcatacattt catggaattc tgctggtatt tctttgattt taggatctaa
    10861 ttcttcttgg tcataagcga ttactgcctt attaagcaca aattcatctg taatatcgct
    10921 tatatccgct ggttggaatt gcagcagctt attcaacaca ttgtacaagg attgcttcct
    10981 tggggcacta ggcagctgta aaaccacatt gtcagacaaa acatctagtg gcagatccaa
    11041 ttgctgagcc agtttgtata agcgttggat atctgatact tccatcactt tcttttccat
    11101 gatttcacca gtatcatttt tttgtaccaa accgccgttg aaagtgatgc tgtagtcacc
    11161 ttcatctacc agtcctaatt cttgcagata atgcgccatc gcagctaagg ggcgtcctgt
    11221 acatagaacg atcttgaccc cttgctgttt tgcttgtgct aatgcttgtt tattctcatc
    11281 tgaaatcagc ttttgttcat ttaataatgt accgtccaaa tcgattgcta ctaatttgat
    11341 cattttcgtt cctacacttt cgtttcgttg attttcgcct cttcattgat atcttccatc
    11401 cgtacagaaa cgatttttga tacaccggat tcctgcatcg tcactccgta cagtacatct
    11461 gctgcgacca tcgttccttt gcggtgtgtg actacgataa attgtgtgtc atcttggaaa
    11521 tcgctcaagt aacgaccaaa acgtttcacg ttggcttcat ctaacgctgc ttctacctca
    11581 tctaagatac aaaacggaac aggacagaca cggataatgg aaaagagcaa cgcgatggct
    11641 gtaagtgctc gttctcctcc agaaagcaaa cttagacttt gcagtttttt gccaggaggt
    11701 tgtacttcaa tctcaatacc tgttttcagc aaatcagttg gttccgtcag tactaattca
    11761 gctttaccgc cgccaaacat atttggaaag acaattttga attcttgacg gatagcttca
    11821 aatacttctt tgaatcttgt ccgcacttca tcatccatct catccatcgt ttcaaacaat
    11881 tggtttttcg ctgctaacag atcatctcgc tgtgttgcta agaatgtatg tctttcactg
    11941 acttgttcgt attgttcgat tgaatttaag tttactggtc ccagtttttc aatctgttct
    12001 tttaaggatg aaacctttgt tctactgtct tcgatatcgg ttgtttcttg atagtcttgg
    12061 gaagctttct caaatgtcag ctgatattct gactgcagat aggtcaaatg attatctaaa
    12121 atcatttcag ctcggtcttt ttggacttct aatttggatt gttccgacag tcgtgctttt
    12181 tgctcacgat tacgctctgc caagactgct tcaagcttat cgatctcctt ttgccttcta
    12241 tctcgctgct ctttggcttt tgccaactcg gcttttaatg tttctcgctg agcagataat
    12301 tcgttaattt gtttttccaa actttcttct gtgacttcat gatcagaaaa gtctgctgtc
    12361 aatgtcgcca actgcttttc tatcgcttct tgacgttcgg ttgcctctgc tttttggact
    12421 cgggcaccgc ggagctggat ctgcagatga ttaaactgct ctttcaagac agcaagatct
    12481 gcttgttctt gtgctttttg actttgtact tgtgctcttc tggcttccat ctggtcgctt
    12541 tcttgactta acgatttgat ttcttcgtcg attttttgtc gttgcgattc aagatctgtt
    12601 tgtttgtctt tcaattcgtt cgtttgcttt tcgtaatctt cgataaactg ctgcagttca
    12661 cgtgtctcaa aagttgagat ttgcttttct ttttcaaaac gttcaagttc atttatgatg
    12721 ttttgtagct gatttgtcgc ttcttgttct tcaaaacgta attgttcgcc tcgtgtacgc
    12781 aaaacttctt gttcttcggc taaacgagct gtttcttgtt gcagctcctg aacttttttt
    12841 tcttgtgctt ggagttgttt atctgcttct tcaaattcac tagtcaactg tttcaattct
    12901 tgattttgta caaacaaact gccttggttt cctcgtttat tcgctccacc tgtcatggat
    12961 cctccggcat tcatcacatc accttctaag gaaaccactc gatattgata gcggatcgtt
    13021 tgcgcgattg cattggcact agttaagtct ttggctaaaa ggatcgttcc tagcaggttt
    13081 tgaaccacag tttggatttg atcgggataa ctgacttgtt cactggcaat ccctataaac
    13141 ccttctacag ctgctgcttg tgtcaatata tgagccggta attgtcttgg tttgattgtc
    13201 gtcagtggaa ggaatgttgc tcttcctcct ctttgctgtt tcaaatacgt gatggcttgc
    13261 cgagcatctt tttcattttc aacgatgaca tgctgggctg ccccacctaa agctgcttcg
    13321 atagctaacg tgaaatctgc aggaacatcg atcagttcag ccactgctcc gacaataccc
    13381 gaaagctgct gtttatgctg caagaccaat cgaacccctt ggtaaaaacc aaaatagttt
    13441 tcttggattt cttgaaggct tttcttacga gcacgtagct gctggacttg attcattaat
    13501 tgatacattt taggctgttc ttttgctaat gcttcttgga actttttccc gttttgttgg
    13561 atcatttcta acttctcttt tgtttcagtt aaagatgatt ttagctgcgc ctgcttttgt
    13621 gtcaattctt ctttttgtaa gatcaatcgg tctactgatg cttctacttc cgattgcttg
    13681 gctaacgtct gcttgctttt tgctgtttct tgtatatatt gacgttctag atacttcagt
    13741 tcgtttccta cagctgcttg ttcttgcatc aaatcaacat attgatctct taattctgcc
    13801 aataattctt tcgttgattt ttggtatttt tctaattctt gctgtgtttt tatgagattt
    13861 gcttcagctt tttggatctc tgtttctttt tctgctgctg ctttcatcaa gctttcttga
    13921 agcttttcaa aatgtttaac ctttttttgt gcttctgcta atgaagtttg atattcttgc
    13981 gagctttttt gtgtatgctt tgtccgctcc tgcaaaacat ctttttgtcc ttctgtctgc
    14041 ttcagttttt ccgaaagatc taataatact tgctgatttt tttcgatcag acgatcggct
    14101 tgcgcatttt ctttacgctg cttcgccaaa atggattctt gttcttggat cgactcagat
    14161 agtttgccta attctagatt gaatttcgca agctgtgctt gtttgttgtc ccaatctttt
    14221 tttgctgtct tgatttcagc aaccatcaaa gagacatcgg tttgagtcag tgtttctttt
    14281 agccgtaaaa actcctttgc tgcctcactc tgggcggcca aaggagttaa ctgttcttcc
    14341 aattcgtgga tgatgtcttg gacgcggctg aggttgtctt ctgtttcaaa aagcttctgt
    14401 tctgctttct ttttccgctg cttgtatttc aagacaccag ctgcttcttc aaagatccca
    14461 cgacggtctt ccggtttact actgaaaatc gcttctactt ttccttgaga aatgattgag
    14521 aacgattctt ttcctaatcc agaatctaag aacaattctt ggatatcttt taatctgcag
    14581 ctttgtttat tgatgaaaaa ctcgctttcc ccagtccgtc gataacggcg ggttacactg
    14641 atctcattgt actccaatgg cagataatga tcactattgt ctaaaatcac tgtgacttct
    14701 gcaatattca gctgcttacg ggtatcggaa ccggcaaaga tgatatccgg catttttccg
    14761 cctcgcagac ttttagcaga ttgttctcct aatacccagc ggatagcctc tgtaatattg
    14821 ctttttccgc tgccatttgg tccaaccact gctgtgacgc tattttcaaa atcaatgact
    14881 gtcttgtctg caaatgattt aaaaccggct atttcaattc gtttcaaata caaagctttc
    14941 cctcacttac ttttacagtg ctgccaatgc attttccgcc gcagcttgtt ctgctaattt
    15001 tttcgatttc ccttgtccag tgccaatcaa ttgatcatct acataaactt cgatccaaaa
    15061 tactcgttca tgagctggac cttcttcatt gatcaatcgg tattcgattg atacatcacc
    15121 tgatttttgc aagacttctt gtagttttgt tttatgatcc atctcatgtg aaaaagcacc
    15181 tgctttgact ttaggaaaaa tcactttttc gatgaatgca tgggtcgtgt cgaatccctg
    15241 gtcaagatat aacgcgccta aaaaagcttc gaataggtcg caaagcaatg ctggtcgcgt
    15301 acgtcctcct gaattctctt ctcccttgcc caacaaaaca tattgatcaa agtgacattc
    15361 tttggcaaat ttcgacaagc tgtcttcgcg aacgatcgca gctcgtgttt ttgtcaattt
    15421 tccttctggc aaatgaggat ataaacggaa taaatactga gaaaccatca gttctaaaac
    15481 ggcatctcct aaaaattcaa gtcgctcatt atccgataat tgcagattgc gatgctcatt
    15541 cacataggat gaatgggtaa aagcttgttc aagcaaattt agatcgtgaa aaacgatgtt
    15601 atagttttct tttagttctt ttgtcagctg gttgtccatt ttccacattc cttttatgga
    15661 tattttttcg atacttcctt attatactgg ttttttgtca aatttgaaat ggttcggtca
    15721 aaaggtaagt aaagctttaa taatcctagt gattgacgag aagttgtgaa aaattcgttt
    15781 agtttcgagt atgaagaaaa aattttgtga aaatggcttt ccatattttt gcataaattt
    15841 gacttaatac cgagaaactg gactttgaac accgtttatt ggagaagtca tgaaatcagc
    15901 gccttgacct gaatattaga gaaataaaca gaaaaatatc aaaaaaccga aaaaggacat
    15961 cgcccttttt cggtcatttt tagtgattat gaacgtgaat ctgctgtaac agaaacattt
    16021 gcccatgggt ttggtacatc ataagaccaa tcccagtctt tgacacggtc gttgactggc
    16081 aatacttcat tacggaacaa cgttggaatc gcaaatgctt cttcaaatgc atattgttgc
    16141 catttttgat atgcttcttt ttggtactct tcatcaaatg ctttgcttga actgatatcg
    16201 ttgatcaatt ttgtattttc ttctgattca taacgagtgt agttgaacgc agcatttggt
    16261 ccccatagtc cacttggatt tggatcagtt cctgtattcc aagcagcttg gtaaacatca
    16321 atttcaggat catcgttttc taatttatca tagaaagaat tgaattcgat cagacgacct
    16381 gttgtgtatt ggacatccaa accaatttct ttccattgtt ggatatagta atctgccaat
    16441 ggttgcgctg tttccccacc ggacatcgaa gcaaagttga ttgttagttt atttccatct
    16501 ttgtcttctc ttaaaccatc gtcatccaca tctttgtagc cagcatcatc taatagtttt
    16561 ttcgctttgt ctagatcttg tgtgaatcct ttcatctcat catcatggta tgactggaat
    16621 actggaggaa tcaatgaagt cgcattgctt ctcaaacctg catagaaacg ttcacctact
    16681 gcattattat ctaatgcata gcccattgct tgacgtaatg atttatcagc catttttgaa
    16741 tctggattgt attccacact ctttgtatct gcattccatt tacctaactt gaatcctaga
    16801 taagtataag aagtttgttc acggcctaag tttgtatagc cagcaatttc tttataggta
    16861 tcgtaagtat ctgttggcat ttggaaaatc atatcatata atttagagtt caatgcttca
    16921 gttgcacttg ccatcggtac agatttcatc gtgatctttt tcaatttagg cgtaccattc
    16981 cagtagtgct cgtttggcaa gtattctact gattctcctg caacgatatt actcatgtaa
    17041 taagggccaa aagtcactgg atttttacgt acttgatcgc ttgattccat atctttgatt
    17101 gctacacctt ctaacgtatg ttttggtgct gcatatgacc agataccacc acccgattga
    17161 agcatgcttg ggtttacttc tttatattcg atttcaactg ttttgtcgtc tatttttttg
    17221 attccggaga ttgtgtcggc acttccatca tgatattctt ccatacctac gatgttacgg
    17281 aaagtgtcgt cataacggat accagtgtaa tctttattcc caatgatttc gtaagggaaa
    17341 atcacatcgt ccgccgttac atcttcacca tctgaccatt tgacgttgtc ttttactttg
    17401 attgtcgctt ttttcgtatc ttcatctaga tcaagcgttg cagctccgtc gtctgtgatt
    17461 ctgaaatcgt catcgtttgc aaatagcggt tcatgagaag gagccataaa agctgcatca
    17521 tatgaatctt ggtaaaactc ccactggaac aatcctttaa actgactgtc cgttgcgacc
    17581 gcagcttcta attcgccgtc ttcgattgca tcatcattat tttttgttgc aattggaaaa
    17641 gttaattcct ctttgttatt gccgttgcct ccagagttgt ttccagaggt atctgtacct
    17701 ccgcccccgc atgctgcaag aacgacagca gacatcagcg ctgcaaatcc aaaaatcgtt
    17761 ttcttcattc ctatttcccc cttcgcttct atactagcct aaccgttggc gcgcatctgc
    17821 agaacgcttg aatgcttgtc caacataatt gatactcaac atcaaaacta aaataaggat
    17881 tgatgcgggt aaccagatcc attgccgatt cactaagact tctccgttac ttgcataacc
    17941 gatcaatgta cctaaactag gtacatttgc cggcaagccg aaacctaaga aagtcaaagt
    18001 tgtctcgata ccgatgtttg ccgcaaagtt catcgtcaaa ttagtaatga ttaatgaact
    18061 tagattcggc atgatttcgc ggaacatgat tttaaaatca ttggttccca ttgtttttga
    18121 ggcactgaca taatctcttc ttgcttcaga taatgtcttg cttcggaata atcgggcttt
    18181 agctacccaa taaaatgcac tcatgatgaa tataaaggac cagacattgt atctggaaat
    18241 aatcgatacg aagacgataa tgatcagcat gatcggtaga atcatgataa aatcaacgat
    18301 ccgcatcaag atgttgtcaa tgatccctcc gtagtagcca gagatgatcc ctaatccaac
    18361 cccgatgatc gaagtaagga tcgtgatcgc aaatccgatc gtaacagagt ttctagcacc
    18421 tatgatcaat tgtcctaata catcacgtcc gccttcatct gctcccagaa tgaacttttg
    18481 tccttgtgtc gaaactgttc ctggtgcagc gtatttgtcg aagatactaa catacatcac
    18541 tttgtcttga tcggtcagca tcgcaccgat aaagatcact aataataaaa ccactagcaa
    18601 acctaatgaa aaaatagcaa ttttatcttt tttaaattct cgagcaatca ttcgtatccc
    18661 cataggagga atactttctt gaactgctgt attgtttttt tcactcatcg atccattctc
    18721 ctttctgatt ggttttattg aatccgaata cgcgggtcaa cgatactcat gatgatatct
    18781 gaaagtaatg tccccactag cgtcgcgatt cctaaaatca atactaagga tgtgatcacg
    18841 gtatagtccc gttggccgat ggaatcaata aatagttttc cgactcccgg ataaccaaaa
    18901 atcttttcga taactacaga accagcaatc aacgaagtga tttcataccc catttgagaa
    18961 gccatcggca acgctgcatt tcggaaaata tgtcgactga atactttatt cgtcggtacc
    19021 cctttggaac gggctgttct gacaaaatcg agcgatttcg aatcgattac ttcacttcgc
    19081 agatattgga ttgtgacggc agtcgccaaa aatgcttggg taattgatgg taacagaata
    19141 tatttcaaac ggtctatcca ttgagtgata aatccacctt gcaaacctag tgtttgtgat
    19201 ccacttgttg ggaaccagcc taaacgataa ccaaaaacaa atagcatgat caagccgaag
    19261 ataaataaag gaacagcaaa actaaagaag ttgtagatta cgacaatctt atccaagatt
    19321 gaattttgat accggccagc aagcatcccc agaggcacag caatcaaata agtaaggaca
    19381 actgtcaaga tcgatagata taaagtgttg atgatccgtt cgccgatcaa gtcagcaaca
    19441 gagcgtttgt ataagaaact ttgaccaaaa tcgccttgca aagcatttcc gatccaacgg
    19501 aagtactgga cataccatgg gtcattcaag ccagctgctt gtcgcatctg ttcgatcact
    19561 gccggatcct gatttggatt gatcaaaccg gtaaatggat cccccggcat cgcttgggct
    19621 aataagaaga tcagaacact taaaataata acttgcggga tcatcaataa aacacgtcgc
    19681 agaatcgttt tccacattag cttgcacctc catctttcaa cgccactttg tgtgtagttg
    19741 tgatcgtacg caaatcgtag actcgaccag tcgcatcata gtattctttt tggttttgga
    19801 tatactcttg ttctactctt cgtcgatttt ctttgtggct ttccctattt tctacatcga
    19861 tttgcggaat agctgaaagc agacgtttcg tatagatatg tcgcgggtca ttataaatgt
    19921 cttctcttgt accgatttct acaaatcgac ctttgtacat aattgcgata ttgtcgcaca
    19981 tgtgttttac tacacctaaa tcatgtgaaa tgaataaata gctgaggccg tattcttgct
    20041 ggattcgttt catgaaattc aatacttgcg cttgaacaga tagatccaga gcagatacag
    20101 gttcatcggc tacgatcagt tttggattgg tagcaacagc acgggctact cctagacgtt
    20161 gacgttgtcc gcctgaaaat tcatgaggat atttatatag cgcatcttcc ggcatcccaa
    20221 cgatatctag cagtcctttt acctttttct tttcttcttg atcgcttaac cgttcaaaat
    20281 ttcggatggg ttcagcaatg atatccaaca ctcgcttttt aggattcaaa ctggacattg
    20341 aatcttggaa gatcatctgc acatccttgt tataacccat ttttttgcgg ttgcttcgct
    20401 tcgttacatc ttttccttca tacatgattt gtccggctgt taccttttct aatcccacaa
    20461 cggcttttcc cgtagtagat tttccagagc cagactctcc cactaaacca tatgtctttc
    20521 ctttttcgat aataaaatcc acaccatcta cagcatatac atgatccgtt actcgattga
    20581 agaatccact gcgaataggg taatgaactt tcaggtcttt gattgtgatt aattctgtca
    20641 tctacacctc tcctttttcg tctctaaagt ggaaatgctt atagcaggag caacgtacca
    20701 agtggttcgg tgcgacttca tgaaggatag gctcttcttc atgatcgctt gctggtatcc
    20761 atggaatacg tggtgcaaac cgacaacctt tacgaggcat gtttttcaga gaaggaacga
    20821 caccttcgat cacatggagt tctgcatcat gatttccttc ttgtggtata gagttcagta
    20881 aagagcgtgt ataaggatgc ttaggatgat caaacagttc ttttacacct gctacttcaa
    20941 cgaactgtcc gccatacatc actgccactc gatcagccat ttctgctacg actcctaagt
    21001 catgagtgat caagatgatc cctgtttttg tttcttcctg aaggtctttc agtaaatcaa
    21061 gaatctgtgc ttggatggtt acatctaggg ctgtcgtcgg ttcatctgca atgacgattg
    21121 gaggtttgca ggcgattgcg attgcgatga tgacacgttg tctcataccg cctgatagtt
    21181 catggggata ttggcgtcca actctcgcag gattaggaat ccctacttgt tctagcaatt
    21241 ctagtgcacg agcttgacgc tgttctgcat tcatctttgt gtgataggaa agtccttctt
    21301 tgatctggtc ttcgattctc atgagaggat ttaatgcaga caacggatct tggaaaatca
    21361 ttccgatatc atttccgcgg attttattat agagcgtttc gttcaggtcg attaaattca
    21421 gatcgttata taaaatctca cctgtaattt ttgtgttatt aggatcaagt aatcccataa
    21481 tcgtagtagc caaggtactt ttcccgcacc cagattcccc aacgattgct aaaatctcgt
    21541 ttttgtctaa agtaaatgaa acgtcatcta ctgcatcgta atagtcatct ttgagtcgga
    21601 atcctgtatg taggttctga acttctaata attggttatc ggacaatcga atacccctct
    21661 ctgcttccta aatggaagtt tttcttaata aaaaaggaca ttacacagaa taaagcgttt
    21721 tataacaaag gttattctta tctttgtgta atgaattatt aataattata tagaaaatcg
    21781 ctttactttg caacataatt tctgtttatc gccagaatta tcagaaaaat gacttttacg
    21841 tgtcaaaaag attaaaaaaa gaaggataaa aagctgtatg cagcttttta tccttctttg
    21901 cttttatttg aaattattta agatggctgc tgatataatc tactgcgcca ccgactgttt
    21961 caatttgttc agcgtcttca tctgaaattt ccgtaccgaa ttcatcttca agctctaaaa
    22021 cgaattccat aatactaatt gaatcagctt ttaaatcatc tttgatgttc aattcatccg
    22081 tcactttatc ggtatctatc tcaaaatgat ttgaaataat tttcgctact ttgttaaata
    22141 cttcttcgcg agtcaacttt ttcacctcca agaatcatac acttgtcaat tacctacacc
    22201 atggctaatt ttactggcat ttttcaggaa tgtccacctt tttttcaatg gaacggattg
    22261 cttcagatat ccaaatacta ttcttcgctt ttttcaaatt gttcgactaa ttgtccaact
    22321 acatctgtct caagcattgt gtggatttgg cggatcgtat agcgaacagc atcggggcct
    22381 gttgctccat gagttttaat gactggtgct ttcaagccaa acaaaacggc accgccatgt
    22441 ttggaataat ccatttctgc tttcaaagaa cgtaagccgt cttttaaaag catagcgccc
    22501 atttttcctt tgatcccttc atttagaata gcagatttta atagattcat catattcatt
    22561 gctgttcctt caatagattt caaaacagcg ttgcctgtaa atccatctgt gaccactaca
    22621 tcagccacac cattgagtag ctcacgagct tctacgtttc caataaaatt caagcttgtt
    22681 tcattctgaa ggagttcata ggcttttttc gtcacttcac taccttttgt tgcttctgtt
    22741 ccgttgttta agagtgcgac acgaggacgt ccgatacctc ggactttacg tgcataaaaa
    22801 gaacctaaaa taccgtattg caacaaatgt tctggtttgt tttctgcgtt agcgccaaga
    22861 tccagcatat cgaaaccggc accttctttc cctactactg gcaaggtaga catcaagcca
    22921 gggcgttcga tatttttgat acgtcctacg atgaacaacc ctgctgctag tagcgcgcct
    22981 gtattccctg ctgaaaatac agcatctgct tcaccgtttt tcactgcttg tgcagcaagg
    23041 accattgatg cagtcttttt tcgtcgaatt gcttttactg gctcatcatc actattgatt
    23101 ttttcgtctg tatggataat cgtgatgttt ttttcatttg ttaagtattt cttgatttct
    23161 gcttcttttc cgtaaagtaa gaattctact tctggaaaat cttgctgcgc taaagccacg
    23221 ccttctacaa ttgcttgagg tgcgtgatct ccgcccattg catctacggc aattttcatt
    23281 gtttccactc ctttttccgt catcagtata aagtatagca cagtctgcta atcgaaataa
    23341 cgattatcct gattttctat ttggaggctt tgcgctaaag gctgatactc aggaagcatc
    23401 tgccaatcct ttatctgcca aagggctgca gcctcttctc tggctacctc caaaacattt
    23461 ccatccgtca ccaagtcagc aatcgcaaat tgaggcagac cagattgacg gaagccaaat
    23521 acttcaccag gaccacgtaa ttccagatct ttttcgctta gtacaaaacc attggtggtc
    23581 tctgtcatga ttttcatccg ttccacacct agttcatttt taggattagc aactaagata
    23641 cagtaggaag catcacttcc gcgtccaaca cgtccacgaa gttgatgcag ctgtgccaat
    23701 ccaaatcgat ccgcatccat gatcagcatg acggtcgcgt tcggcacgtt tacccctact
    23761 tcaattacag tagtcgaaac taatatctgc atctggttgt ctttgaaggc ttccatgatt
    23821 acttcttttt cctgattctt cattttacca tgtaacaagc caacttcata ttttggtgca
    23881 aatagttcac gaagtttttc atagatttcc actgcatttt ttacatctaa tgcttctgat
    23941 tcttcaatca gcggacagat gacatacatt tgatgtcctc ttgccagttc ttttttcgtc
    24001 caatccagta cactgtccaa ttgaggtgtt cttacccagc gtgtttcgat cgggatacgt
    24061 ccagctggaa gttcatcaat gatagataca tccatctcac catatgctgt aatagctaat
    24121 gttctaggaa tcggagtcgc tgtcataaat aagacatctg gtcgccagcc tttttcacga
    24181 agtactttcc gctggttcac gccaaaacgg tgctgctcat ccgtaataac tagacctaaa
    24241 ttctgaaatt cgactccatc ttggatcaat gcatgtgtgc cgatcacgat gttaatttcc
    24301 ccttgctcta gtttttcaag gagctcacga cgttcttttg ctttcgttga ccccgtaagc
    24361 aatgcgatgg ttacttcatt gggatcaaac agctgttgca agctttccat atgttgttgt
    24421 gccaagattt ctgtaggcac catcaacgca ccttggaaac ctgctgtaac ggtagcgtat
    24481 aacgcaatcg cggcaaccac tgtttttccg ctacctacat ctccctgcaa aagtcgctgc
    24541 atatgctgcg gactgcgaag atcccgacag atttcattcg ttacacgttt ttgtgcattt
    24601 gtcagttcaa aaggtagctt ttgagtaaat tctttcaatt tttggacatc ataaaggatc
    24661 tccaaaccat tcgtttctgc tttttctgct tttttcaatc cttgaagacg catttgaaat
    24721 aaaaagaact cttcaaaaac gacacgtcgt ttggcttgat ggttttcttc gtggtctttt
    24781 ggaaaatgca tacttcttac agcagaagct cggtcaagca gtcgatattt ctccacaagg
    24841 ttgtttggca gattttcttc aatcaatgtg ccgtattctt gaaacccttt tttgattaga
    24901 tcaactaatg tcgtttgacg aattgatttg ttgacgtgat atatcggcga aaagtcatcc
    24961 attgtttgag aacctaaaat cttcatcccg ttcaatgctt tacgctttgc atcccattta
    25021 ccgtatacgg cgatttcctc cgataaaatg actttttctt ttagataagg ttgattaaaa
    25081 aaagaaacgt tgaacacatc atgttcttgc atcatacgaa attgcaatcg gcttttttta
    25141 taaccaaatc gattcatcac aggaggcgag actacgattc ctttcaaagt aaccttttct
    25201 tgatcttgga tctcgtttag atttctttcc tgaatatctt cgtagcggaa aggataataa
    25261 gtcagtaagt cttcaatcgt ttggatgccc aagctggcaa gactagctgc tcttttttct
    25321 ccgactcctg ccagcatagt gattggatca tctaaagaac gcataaattt ttcctccctc
    25381 ccttaacaaa aaaaggactt ggtcagcgat catacctgat cactaaccga aggcctttta
    25441 tgaatgaata ctgtgttaga aagatattct gacacagaaa ttattcagca gaaaatagat
    25501 aaggatagac aggctgatct ccttggtgga tctcgatttc caaatcagga tgtttttctg
    25561 ttagtttctc agcaaattca tttgcttgtt caactgttcc ttcatcacct gccaagatcg
    25621 ttacgatctc tgtgtcctca ttgatcattt gttctagtgt acttaacgct gttgctgtga
    25681 tatctgggtt agagatcagg atttttccat cgatcatgcc caaaaagtct ccttctttga
    25741 tctctacacc gtcaattgag gtatctctga tcgcgtgagt gacttgaccg ctcacaacgc
    25801 tagacaacat ttctgtcatc gtttctttgt tttcttctaa agaagcttga tcattgaatg
    25861 aaagcatagc tgtcaatcct tgggaaatcg ttcttgaagg aacaactgct actgggatat
    25921 ctgctacttc tgctgcttga tcagctgcca tgaagatgtt cttattgttt ggcaagacaa
    25981 tcactttatc tgcgtttact tcttgaatcg ctttaacaat gtcttccgta cttggattca
    26041 ttgtttgccc accactgata acataattag cgcctaaact ttcaaacagc tcttggacgc
    26101 ctttaccagc agcgatcgct acgataccat acgggatacg tggtgtttct tttttcgcaa
    26161 actcgttcac ttcttcatcg tgttccaaaa tcgtctcatg ctgcaagcgc atgttgtcga
    26221 ctttgatttt gactaatgaa ccgaattttt gtccataatt caagacttct cctgggtttt
    26281 ctgtatgcac gtggactttg atgatctcgt catcattgac cacaagtaaa gaatctccta
    26341 taccatctaa atagttacgg aattcttcgt aatcgaatgt actatcgact gtaggtcctt
    26401 ctccgatttt taccatgatt tctgtacagt aaccaaaatg gatatcttct gtcgccattt
    26461 gaccttggac actgcgatga tgttctgcat tgaccatatc atccatttct gctggagaag
    26521 gttcatatgt ttcatccgct tggaattctc cattcaatgc acttaaaaag ccctcataaa
    26581 caaacagcag tccttgccct ccactgtcta cgacaccgac ttcttttagg actggaagca
    26641 agtctggagt tttagctaaa gcacgctttg ccccttttac aacagctgtc attacttcaa
    26701 cgacatcatc agtacttttt gctttctttt ctccagcttt cgctgcttct ctagctactg
    26761 tcaaaatcgt tccttctact ggtttcatta ctgctttata cgcagtttca actccatgag
    26821 tgaaggctgc agcaagatcg gaagcattta atgagacaac atctggaatt tgcttagaaa
    26881 atccacgaaa caattgagac aaaataacgc cggaatttcc gcgcgcaccc atcagcaatc
    26941 cttttgaaag cattgctgct aattctccta ctttttctga ggttgaatct actactgcct
    27001 tagctccact agtcatagat agattcatat ttgttcccgt atcgccatct ggcacaggga
    27061 atacatttaa tgaattgacg tattctgcat ttacttgcag acgattcgca cctgcctgga
    27121 ccatttcctg gaactggctt gcacttattt ctgttacact cacctagata atcctccttc
    27181 agatcgactg ctgagttacc agccagtctc ctgcctagtc tggcagtaca cgaacacctt
    27241 gtacaaagac attaactgaa ttggcagtta cgcctaataa tgcctctaga ttgtatttca
    27301 ctttttcttg gacgttgcgg gaaacttcag agattttcgt accatagctg ataatcgtat
    27361 aaacatctac agcaatacca ttatcttctt ggcggacaac tactcctctt gagtaatttt
    27421 ctttacgcaa aatctcagta atattatctt taatttgatt tttgctggcc attcctacaa
    27481 caccgaacac atctgtcgcg gcgccaccaa caactgttgc aattacatca ttggtaattt
    27541 caatggttcc agctgacgtt tgaattttta cagccatgaa tgagcctcct taacgggtaa
    27601 aaaactccca tttttcttct atcatatttt atcatagcgc aacttgaaat aaaaggcagt
    27661 tacccaaagt actcaaaaac cttgcaaaat ttcaggtata accttgttta atttacaatt
    27721 attcttctca attgtcaatt gtatctatga aaatgtactt gcaaatttcc attctatatg
    27781 atatgttagt ctggtatgag ctgaattatt ctattgctcc aaatcaaggc aaaggaggaa
    27841 attaccatgg caaaagtttg ttactttaca ggtcgcaaga caaaaagtgg aaacaaccgt
    27901 tcacacgcta tgaactcaac aaaacgtact gttaaaccta acttacaaaa agttcgcgtt
    27961 atggtcgacg gaaaacctaa aaaagtttgg gtgtcaactc gtgctttgaa atcaggaaaa
    28021 gttgaacgcg tttaattgaa tgatacttgg accgttcaga tagtgaacgg ttttt
//
LOCUS       DACCVZ010000030        28016 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.030, whole genome shotgun sequence.
ACCESSION   DACCVZ010000030 DACCVZ010000000
VERSION     DACCVZ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.030"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(43..300)
                     /locus_tag="IVW63_001345"
     CDS             complement(43..300)
                     /locus_tag="IVW63_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859627.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARVFFNRIRQKSPILYRWVMNAVRYEGYRW"
     gene            complement(467..2437)
                     /locus_tag="IVW63_001346"
     CDS             complement(467..2437)
                     /locus_tag="IVW63_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859628.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            complement(2452..3318)
                     /locus_tag="IVW63_001347"
     CDS             complement(2452..3318)
                     /locus_tag="IVW63_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859629.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            complement(3308..3541)
                     /locus_tag="IVW63_001348"
     CDS             complement(3308..3541)
                     /locus_tag="IVW63_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP7859630.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            complement(3553..5715)
                     /locus_tag="IVW63_001349"
     CDS             complement(3553..5715)
                     /locus_tag="IVW63_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859631.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYQKEEKEAKAKK
                     AKVKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEEVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLLIPDDPNMFESEVEEATDFYSAVEQLEVATN
                     GLERLAETFNSSEEVEFEALAEDIPDEKEALFADDDKPTEAENQEVSIEETQTQIQTE
                     TYQQSKIDEKPESQSDKENYVYEVEKIVSESDVPKSLDADFLEKNFEQIIADKFQPVV
                     LDEINDPVDLNEEMLSIAELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGK
                     QMLADELLRIEQATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSSIIRKDYDMA
                     KQAYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQN
                     QEAKEVVVERIINSLKPEIENSLTDVQEKTLEIVEKTKSENEAEFHDTKEKITDVVVK
                     YFANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYRSNSEKLAEQS
                     EALREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTIL
                     GSSYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVIS
                     IDGKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            complement(5715..5957)
                     /locus_tag="IVW63_001350"
     CDS             complement(5715..5957)
                     /locus_tag="IVW63_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859632.1"
                     /translation="MVFDREKMLAHANEVLMSGLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTIDRKKGVLQ"
     gene            complement(6067..6405)
                     /locus_tag="IVW63_001351"
     CDS             complement(6067..6405)
                     /locus_tag="IVW63_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859633.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNEQLG"
     gene            complement(6804..10445)
                     /locus_tag="IVW63_001352"
     CDS             complement(6804..10445)
                     /locus_tag="IVW63_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859634.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLIDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGQDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDENGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEDDEITLDQTHQELRNEMSGEDVSDRVHRELGNGASGESQSRELNSNFDNSA
                     IRNDTALKDRESLSKETDKEQSDVKKKFIPTPNINQTDKYETNNGLGMSKDNQSIREP
                     ELTNDNNRTNNSKSTSDNSGKSNQSTKKPSTAKSAVEYLSKTGKNVYTSADKALAKSP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            complement(10448..12397)
                     /locus_tag="IVW63_001353"
     CDS             complement(10448..12397)
                     /locus_tag="IVW63_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAP7859635.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKAEDKDNEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQM
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFR
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPKKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            complement(12439..13497)
                     /locus_tag="IVW63_001354"
     CDS             complement(12439..13497)
                     /locus_tag="IVW63_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HAP7859636.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLEERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVNKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            complement(13615..14070)
                     /locus_tag="IVW63_001355"
     CDS             complement(13615..14070)
                     /locus_tag="IVW63_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859637.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            complement(14654..15457)
                     /locus_tag="IVW63_001356"
     CDS             complement(14654..15457)
                     /locus_tag="IVW63_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP7859638.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKALSDKLGTLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            16437..17660
                     /locus_tag="IVW63_001357"
     CDS             16437..17660
                     /locus_tag="IVW63_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAP7859639.1"
                     /translation="MESYQFQIFKLVPSLERRGNRMKITEKNVNPKFEPTESNLKKFD
                     LTVTLSNELVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLEDHFTQYAFDQVVNLTSKYAISFFQLFTKDFNLYLANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            17695..18462
                     /locus_tag="IVW63_001358"
     CDS             17695..18462
                     /locus_tag="IVW63_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP7859640.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFEDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LNIDFAKVRKGRNYNFAVQFNISSEFDEKTYREKKLG"
     gene            18654..19052
                     /locus_tag="IVW63_001359"
     CDS             18654..19052
                     /locus_tag="IVW63_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAP7859641.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(19359..19754)
                     /locus_tag="IVW63_001360"
     CDS             complement(19359..19754)
                     /locus_tag="IVW63_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859642.1"
                     /translation="MKQEKRKMKQTQTETVNDTLADQLAGYYKLFEMGKAQRLIHYLW
                     KYKILFLFWESTLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVIS
                     DAGIERNIKRVSFKITLNKPTDKKLSEAF"
     gene            complement(19755..20132)
                     /locus_tag="IVW63_001361"
     CDS             complement(19755..20132)
                     /locus_tag="IVW63_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859643.1"
                     /translation="MKSKKETEPMKATHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            complement(20122..20517)
                     /locus_tag="IVW63_001362"
     CDS             complement(20122..20517)
                     /locus_tag="IVW63_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAP7859644.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            complement(20584..20769)
                     /locus_tag="IVW63_001363"
     CDS             complement(20584..20769)
                     /locus_tag="IVW63_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HAP7859645.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            complement(20851..21105)
                     /locus_tag="IVW63_001364"
     CDS             complement(20851..21105)
                     /locus_tag="IVW63_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859646.1"
                     /translation="MNYTDEEQITLEYVFIDEEGEEIEKVLIISSKDLENALTYEPYE
                     STVTVNEFLDTYTSDDTWEIMNICNANNIQFAEKTNKSFY"
     gene            complement(21127..21372)
                     /locus_tag="IVW63_001365"
     CDS             complement(21127..21372)
                     /locus_tag="IVW63_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859647.1"
                     /translation="MWTLEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTS
                     LECVWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            complement(21379..21663)
                     /locus_tag="IVW63_001366"
     CDS             complement(21379..21663)
                     /locus_tag="IVW63_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859648.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGIVKQLIKDREFKKFNSRQVYN
                     RQLKKAILKHKDSFIGNLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            complement(21766..21948)
                     /locus_tag="IVW63_001367"
     CDS             complement(21766..21948)
                     /locus_tag="IVW63_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HAP7859649.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAENHTSKATGLAVSS
                     FLTLLTLFVTLSFSFV"
     gene            complement(22154..22693)
                     /locus_tag="IVW63_001368"
     CDS             complement(22154..22693)
                     /locus_tag="IVW63_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859650.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGDYSSANEVIEEKKGYAKNGLE
                     IVDTKVTKIYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKRQLDRIKEESNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVA"
     gene            complement(22806..23072)
                     /locus_tag="IVW63_001369"
     CDS             complement(22806..23072)
                     /locus_tag="IVW63_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP7859651.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            complement(23074..23295)
                     /locus_tag="IVW63_001370"
     CDS             complement(23074..23295)
                     /locus_tag="IVW63_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HAP7859652.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKQLMKEHEENDQSISHEDMLKELGL"
     gene            23521..24339
                     /locus_tag="IVW63_001371"
     CDS             23521..24339
                     /locus_tag="IVW63_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7859653.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            24343..24639
                     /locus_tag="IVW63_001372"
     CDS             24343..24639
                     /locus_tag="IVW63_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859654.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(24821..25174)
                     /locus_tag="IVW63_001373"
     CDS             complement(24821..25174)
                     /locus_tag="IVW63_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859655.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKKKPTDHNPIQQEHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(25194..26249)
                     /locus_tag="IVW63_001374"
     CDS             complement(25194..26249)
                     /locus_tag="IVW63_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HAP7859656.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYKNI
                     LSFSLANLARLEDQSDDVLTVNLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDETLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            26465..26863
                     /locus_tag="IVW63_001375"
     CDS             26465..26863
                     /locus_tag="IVW63_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859657.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KVAVEKYFDSLEESAKEIFNGEKAGSYELDGIRFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
BASE COUNT         8666 a         5048 c         4276 g        10026 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaaaaaaact ctcgcttttt cttcatcagt aaagttttta tacaactgat tacaataatg
      181 aggtttttga agtttctgaa tacctatact aacttcaaat ccttcttcat gttgaattag
      241 gattacttct gtgtctctac ctagaaatat tcgatctaaa atttttatgt ttggtttcat
      301 tatttaacct ccactataat tatttcactc agtaaggttt cactttatga aatttctata
      361 gttctctttt cacaaaacgt accatgttct ctaagactgt ttttagtctc aaatatacat
      421 gttttttctt atcctttcct tatacactca aaatcaaaga taaaacttaa agaataaact
      481 ctccaataac aaaattatta gtcagatcca ctggtctcct gatctgaaat ttattacttc
      541 ttcctgttgt caaatactgt ctcaaatcaa cagaaagttt ttgatcatct tctccttttc
      601 tagcaggagc aacttttttt tcatacttca ttaactctcc actggtcatc tttccaatga
      661 tagtgtaatt aaaatcactt tcaaaacttt ggtaaatttt tccatctgta ttgaatatat
      721 cagctgtttc aatatcttct ttgtattcat tgtcttctcc tgaaccgatt gtatcaaata
      781 gaaaggcaag acgaattcca tcttcttcaa gcattgttaa tcttttttta attagcccaa
      841 cggtttcaat agataactta tcgaagccgt gaatcataac aatatcatct ttttttgctt
      901 gtgatgtgat gaaatcaaag gtatttaaaa attgagcttc cataacattg gtttctgctc
      961 ttagatcacc taagttatag taaaactgta atttgtcact tttaccgatt tctttcagtg
     1021 tcgttctttg attaaacatc ctagagaagc tgtctaatgc tgttctcaat gtgtctttta
     1081 atacaataat acgatcgact tctttttcag taccagattt tttggctttt gtttcagcat
     1141 tagtcaaata gctaataaaa tccccaagaa ctggcattgt atcactactg ttcaccaaaa
     1201 gttttgaacg ttcttcataa ttaatatccc aaagtttctg acttatataa aagttaccta
     1261 attctttttt caataaaact ctagttgcag aatctaatgt tctgcctgct aacaaataaa
     1321 aaatctgagt tagtttatcg agattccgtc tatataaatc accaatgtcc ttttgattac
     1381 caaaaagctc caaagagtta agaccttctt cagccaaatt aaccttttct attacactgt
     1441 ttaacgaagg tttggcaaca aatgttctac cagttggatc accaaagtaa tcaaatttat
     1501 ttaagacaat atgaaaagtt cgtttatgat ttgccattgc attattagca atcaattgcc
     1561 cccaaagtga tgatgctgag attttttcat catagccttt aattgtagcg tttttgtgtg
     1621 atgccactaa aactttactt gtaaaagaat catccagtgc cataaaagct acaccacttg
     1681 cgtagctagt agacatagtg ccgatagccc atccattcgc atcatctaaa cctttgcgaa
     1741 ttgcatgatc atttcctgca aaatccgaac tcatagacgt atactcatag acattcccga
     1801 ttggttcact taaaagtcta tcaaacagat cacgttgatc tcctccatat gacataagct
     1861 ttaatccata cattttttca tcatacaacc gttggagttt aattagctgt tcgctgattt
     1921 tattaggaga atcggatact aataggattt ctagcttcca atcaataatt ttatttgcca
     1981 tgctgtctag taaagatgct gtattcaaat ccataatccg cataacagtt ttgctaattt
     2041 cagcatctga attttttcct tctaaattat tttcataact attcgttgat cccccaacat
     2101 tctcgtgcat tatttcttgt tgatcttttt gtgacactgg cttatctgct tcaattagat
     2161 aggcttttac cccttctact ctcacttcag gaatagcttt aaccatccaa ccaaatccat
     2221 aatttctatt cattccataa gtattcacta atttcacaat tgttccccac cgcttacctg
     2281 tcctaatgta agatggtgta aattgataac caactaaaga tgttaaatca ctaacaaagg
     2341 tattattcac tacctttgaa tttctagttt tttgttcttt tttagttttt ctcttttttt
     2401 tgaaatttaa tagttgtgat ctacccataa tttccattta atctctcacc tctatttcag
     2461 tgcataaata tcagataata tttcttttgt ttgtttagct gacaactgag tgacactata
     2521 ataaagtcct ctactcgtat agttttctaa acgttccaca ccttcatcca ataccatctt
     2581 agattgagat ttcaagataa gatattggat tactgttgtt ttcacaccat caatatattc
     2641 tgatacaaat cgttcttgct gatctattat gtcaaagact gctttgttac tccttgcatt
     2701 tcgtttttgt attttcatat ttcgagtttg tctttccgta ttctgaggtt gagatgaagt
     2761 gattttgatt tcagctaagg aacgatctct ggtattttga tattgtattg atttcgattc
     2821 ctgagccata acttcttctg gaaaagcggt tagtgatgta gccccatcta gattgaacat
     2881 taatgctaca ctcccatctc gatatacgat tgttccatct tgtttcactt ttaaaatctc
     2941 tgtgcctcga aatggtttct ttttccccat agatactctt gctgaattaa ctactgattt
     3001 gaacagtcta atagaaccag aaatcaatga accactagat ggatcaataa acatatactg
     3061 gctaattaga ataagaaatc caattatcat taataacgtt ggaacaaaaa taaatttcag
     3121 tttaatcgta tcagaaacta agtaaacaat tgatccaaga acaacgactg caacaactat
     3181 agctgataca attaatcttt ttgctgtaac agaataggtg ctattgacat gcttttcaag
     3241 ccattcaact ctgacaattg tttcagaagg tttttgatgt aagttatgtt taaatccata
     3301 gtttgagtta tctgccatca gaaatacttc ctttcacgtt caacttacgg taaacaccta
     3361 cagttatcac tattgcaaca ataagcaagc caattaaaga tattgacttg ctcattgtct
     3421 cgttcgtttg tggtagttca tttacctgat acacgagctg tgcttcctgt aagtgctgag
     3481 aagaggtcat gttttcttga ttgttttgaa ttactggata aactattttt tcttctcgca
     3541 taatagccct ccttagttat tatcagataa gtgagcttga attttgtact gatttccgtc
     3601 tggagttttc acaactgctt tttctccatc aatagaaatc acttcagcct tagttgtttt
     3661 cccatcaata ctgatgacaa catctttccc aactttgaac tctgtagttg gtgttgcttc
     3721 atagctacta tttgttgaag cagagttcgt atttgtccca atcgaatttt ccactctcga
     3781 aatagatgtt tgagtttgag cctgtgcttg ttgattatta tgactaataa agtaggacga
     3841 tcccaagatc gttccgcaag ccattgcagc gacagaaatg atagtagcca tctttttact
     3901 tgtaaaatca cgttttgaac ttgattgatt ttctgtagca actgctaatg atttcgtttt
     3961 ttctgccatt tgagctagat cacttcggga acgagataag tcttctctta aagcttcact
     4021 ttgttctgcc aacttttcgc tatttgatct ataaccctct gctaaatctt tgacctcttt
     4081 cattcgatct ttatattctt cgatagtttt ttgttgctct acaagttttg tttctaattc
     4141 tttcgtgttg ttagctactt gcttttcaac ttcttctttg ttcgcaaaat atttgacaac
     4201 cacatctgtt attttctctt ttgtatcatg gaactcagct tcattttctg actttgtttt
     4261 ttcaacaatc tctaacgttt tttcttgcac atctgttaat gagttttcaa tttctggttt
     4321 caatgaattg ataatccgtt ccaccacaac ttcttttgct tcttggtttt gtttcaatgc
     4381 atcgttttta atagattcaa ttgcttcttg gtactgttga tcaagacttt cttcagttgc
     4441 ttttctatat tcatcttctt gttgtttaac ttctggtaaa tgttcagcat cataccgttg
     4501 ctctagtttc tttagttcag catccaaata agcctgtttc gccatatcat aatctttacg
     4561 aatgatactg gatttttcca tcactaaatc atcaatctta gatgcttctg cttcgtagct
     4621 ctctttagca accgataatg tatttgtaaa ctgattttga ccatttaatg aggttgcttg
     4681 ctctatccgc aaaagctcat cggctaacat ttgctttcct ttgaggatca attgctcctt
     4741 cgtcttattt aattcactgt tgattttatt attagcgata gaaatacgag cattcatact
     4801 ctctttagct aaaaacagca atggtttcaa ctcagctatg gatagcatct cctcgtttaa
     4861 atcaacagga tcattaatct cgtctaaaac tacaggttga aatttatcag cgatgatctg
     4921 ttcaaaattt ttttctaaaa aatcagcatc taagcttttc ggtacatcac tttcggatac
     4981 gattttttct acttcataaa cataattttc tttatcactc tgggattcgg gtttttcatc
     5041 aatttttgat tgttggtagg tttctgtttg tatttgagtt tgtgtttctt ctatgcttac
     5101 ttcttgattt tctgcttcgg ttggtttgtc atcatctgca aaaagagctt ctttttcatc
     5161 tggtatgtct tctgctaagg cttcaaattc aacttcttca gaagagttga aggtctcagc
     5221 aagtcgttct aatccatttg tagctacctc taattgctcc actgcgctat agaagtctgt
     5281 agcttcttca acttctgatt caaacatatt aggatcatcc ggaataagta ataattgacc
     5341 actactatcc ataaaacgga cacctgctaa tagcttctct ttaaattttt ctggtagatc
     5401 agctacataa ttcaaacttg acttcaatag aacgacatac ttttcggaat cgagaatagc
     5461 atcatcctca tctataactt cctcactgtt gagcttttgt acatcttcaa ttaccatata
     5521 atttttcttt ggtaaatctt tggtcagcaa cgcatcgaat tctttccata cctttacctt
     5581 agcttttttt gccttcgctt ctttttcttc tttttggtac acttcgagta attgtggctt
     5641 caaagagagt gcaactacag gaactgtttc tgccacataa ttaatagatt cggtaatatc
     5701 tttgaatttt gccattattg taaaactcct ttttttcggt caatagttct tttctgtttg
     5761 tctagcatat atacatatgc tttttcgaat ttaataagcg tttcaagtct ggctttttca
     5821 atctttttac tcccattccg ataatcatag aactggttaa cattcatatt cattatcttt
     5881 gccagttcgg tacctttcag accgctcatt aatacttcgt tggcgtgagc taacattttt
     5941 tctctatcaa aaaccatctt acatttactt tcttccctca cttctaaact acgcttggag
     6001 cgtagttttg tggtaaaaag taaattgaac aaatcggcat attatccaaa tttgttcaat
     6061 tcacttttaa cctaactgtt cattttttgg aaattttgaa actagataga taccaacaac
     6121 tggaataagt gctgatataa tattagcttt ttggttcaaa tcattacctg ttttagtacc
     6181 cattgtgtaa agcataacgg ttgtaattac agggataata aagattgcaa taatcgcccc
     6241 aacatatttt aatccatctc cccattttgc atcaccaaaa aatttcattg cagtgaatcc
     6301 tggtttcaac gaaaaaacga atgccaagaa atacaaaaca acttgtacta aagttttcat
     6361 atcaggcgtc attccgctaa ccaaattttt aatagaatcg aacatataaa aacctccttt
     6421 ttaatatttt taataagtta attatatcat cgacaaatct tatttgttca cttgtcaatg
     6481 atctaactaa gaaaaagacg tctcgatatt tacatcttta tgttatcata ataacataaa
     6541 tttttgatga ttaaaagaga ttttccatta aattatttca ttttttttat tggctaaaaa
     6601 tgctggttta tcaagttttt gtttagataa taattctgtt ctttaccagc ataagccctt
     6661 tttaattaaa caactttgaa cagtaaatat ttaattcatt tatagataat tttaaaaatt
     6721 tttttgcata aatagaaatt tttcttgaca tcttcagtta aaaataaaag taaaaagaag
     6781 gagcaaatca atgctccttc tttttattcg tcttcagact tattttcagt tgatttctga
     6841 ttaccgtatt ttacaatata gtccttgact gacatggtag atttcttcac tactttacca
     6901 gtcttggatg ctcctgtagc agtagccttg gcaaccttag ccgttccttt acctatttta
     6961 atagcttcgt ttttagcttc ataggttatc cctgctagac taccttttgg agattttgct
     7021 aaagctttat ctgctgaggt gtaaacattt ttaccagttt tcgatagata ttcaacggct
     7081 gatttggctg ttgatggttt cttggttgat tgattagatt tccctgaatt atctgaagta
     7141 gatttagaat tatttgttct attattatca tttgtcagtt caggttctct aattgattga
     7201 ttgtctttcg acattcctaa tccattattt gtttcatatt tatctgtttg attaatatta
     7261 ggagtaggaa tgaacttttt cttcacatct gattgttctt tatccgtttc tttcgatagc
     7321 gattctctgt ctttaagtgc tgtgtcattc cgaatagcac tattatcaaa gttactgtta
     7381 agctctcttg actgactttc accagatgct ccatttccta attcccgatg cactctgtct
     7441 gacacatcct caccactcat ttcatttctt agttcttgat gagtttgatc taatgtaatc
     7501 tcgtcatctt cattctcagg aattgcaaca gcaattggcg tatgccgttg ttgttcgagt
     7561 tctctatttc gatctgccac aagcgcatct ctcgtctcaa tgatattccc attctcatcg
     7621 actaaatcgc cattcacatt atatccatcg ctgtgtttac caagtttatt accaaactca
     7681 tcaacaagat ttccatcttc atcaactaaa cgcccttttt cgtcaactaa acgtccgtta
     7741 ctatcctgac caaaatcacc atttagcaac ctgcgtccat tttcgtcaac aagatttcca
     7801 tcttcatcaa ctaagcgacc tttttcatca attaaacgtc cttcgctatc cataccaata
     7861 ttaccatctt cactatcttc caatggttta ccattagtat ctataaggtt tccatcttca
     7921 tcgatcaaac gccctttttc gtcaataaag ttgcctttag catctttacc gtatttacta
     7981 tcttttaata tttcaccatt ttcatcgaca aagtttccgt tttcatcaac catacgtcct
     8041 aaatgatcaa tatattgttg ggagttatta cgtagttgat cttgacgaac taaatctttg
     8101 aaagaggtat tattgattgt tgaaccaact ccgccaccgt tgaatgacat tccttctggt
     8161 gtttcaggaa ttactttatc agcaatggac ttagcatcag cattgctatc tcccatattg
     8221 ttcaaacgtt cagccatttt ttgcgctcca actgctccaa gacctcctgc aaccatatct
     8281 tttactgagc tgttgccacc atcataatag ggatttttag ctccttggct tttcttgatt
     8341 gctttagaaa cgccgtccac aactcgcaca gcatcatttc tattaccaaa taataactta
     8401 gcacgttcat caaacccaaa cgctacttca agtggtaagc caataagcat attaatcaaa
     8461 ttatttactt tttcgccttt tttaaaaact aaaagatatc ctacacctaa aatcatagca
     8521 gatcgaacaa tatttgctac gccatcgcca actaatgtat taggaatgaa tcccacagca
     8581 gtatcaccaa atgcacgaat aaaagtaatc agaaagatag gtaattgtag tccgatcaga
     8641 gatgttgtaa caacacctaa tgaaattgcc atcacacctg ctcctgatgc aagtgatcct
     8701 gttagaacta cttcccaaat ccgaataaat tcacgtttaa atgctttcac gatattcaca
     8761 ttgaacatcg cccaagcaca tgctaagtaa agaactgcta aaacgattga ttcagcgttc
     8821 atcgctagcc acgagccaaa cttacccatc gctccatgac caactaagga tgctgtacgc
     8881 cattctgttt ttactgttga catattctta gcactgcctt gaattcctga aggagcgata
     8941 ttatacgcat aaaacttagc tcctgatgta tcaagtgccg attggagcaa taaagctacc
     9001 gactgtgtgc taaaagttgc attgttagca acgccccaag gttgagtagc atcaaagtta
     9061 tgcgctgttc cttttccatc aggcttgcga ttgtcgtctg tcacattttg atttgctgac
     9121 caaatatatc catttaaatt ggttggtttc ttaattgcac ttccttcttt tccatcccct
     9181 aaattatagc ctgtccaaac agcaggcgct cttcccatat aagcatcatt ttcggcgaca
     9241 ttaacatcac cggcataagt attaatattg aaagtatcat tcgatgacca ttcttttaat
     9301 agagccatac cgactgaatt agaatctaga tcattatttt gtctggcata actgctagta
     9361 ttgatcgctc ttatcattgc agatttttta gatggttcat aatctgtatc aacgaacttg
     9421 atttcggatg taggctttcc gtcaggtaca tcaccaccag tatcagatga tggagcaaga
     9481 ttttgagtag aagcccaaag tcttgtgtta atgatgtagt cagaaacaac atttgttggt
     9541 atatctccat ctttttttgc tgactggatg ccgttgatat aaactcccaa tagcgatcct
     9601 gccactggta agaatataaa caatacaaaa atacgaacaa tccatttttc aagtactggt
     9661 gataatccct tcgagttaac accatctttc gacaataatt tcattccttg ataacctagt
     9721 attgctgtga aaaagagcat agataagctt gctatcgctt taaataattc attatttaat
     9781 cccaaattgt taagcaagct agttaatgct ttagataccg gattagatac atccgatcca
     9841 ccttctcccc accccataag agaaaatata ttcatactca tgaaaaattt tccaaggagt
     9901 tcatttatgg attcagcaat attagaaagg attaaactaa ttgatccgat aaaactacca
     9961 atcgtcctac caatacttcc tagaatggat gatgcttgac ttgcaatagc atttcctgag
    10021 actgtttcaa tatatccgta gtaactataa gttgctaaag tagatgctag ttgcgtacct
    10081 gcattacccc ctgcaatcga attaccttgt ttagaaatgt cagaataagg gaaatcggca
    10141 ctgataccac cttgtcctaa caaattcatt tgtccagttt tagcggcact atcattgact
    10201 tctttatctc ccattaggat acgagcatat agtgtccaca ttccttgttc tgccggttta
    10261 ctttccgcat aagcaacgtt cttatttata actgtttctt gtttgctatc ttgattgtca
    10321 ggagttggat cattcattcc aaaaggagcg cctaaagtaa ctgctaatac tcctccaata
    10381 actagacctc ttacgaccca tcgttttatt ctaaggtttt gtagtaaata tttcttgaat
    10441 ttcatagcta cgcccctcca atcgaaaata caatcttgtt ttctttactt tcagcaacgg
    10501 aaggctttgc aataatttca gcattagaat caccttttcc ttcaaacgct ccggcttcac
    10561 tcaacttaac atcgaatatt tttgcgtttg gataagtaat tattgcttca gtaatcgctt
    10621 cttcaaactc agattcaact aaatgcaaga tattccttgc accccctgat ttagaatcct
    10681 cttgtgaagc catgtcaaaa actaagtgca tggagagatc gtctgcataa aaattttgac
    10741 catatactct ttctttctta ggtggaagac gtaaatctat atttaaatgt tttcgtacta
    10801 attcagcact cttcaacatt tcattataag caatttccag aagagtttgt tcggataaag
    10861 cccaaaatgg aactattcgt ccaaatcggt taataacttc aggctttaga ccttcaccaa
    10921 tcaaggcttg tttgatccct gatgcgactt ttcggtattc tctttttagt tcagtgctgt
    10981 attcattaga attttccttg tttgtaacac gagatagtga gctatatcgg tttaacgaat
    11041 cgaacatctc cgcacctgca tttgttgtcg caaataaaat tgtatttgac aatgaaacgg
    11101 tgtcgtgaac ttctcgatca tcccatcctc tttcagtaaa acttatccta ccttcatcta
    11161 aaattgataa aaaggcatcg agtgtttcta caccagcttt ctcatattca tcacacacaa
    11221 taatcgcaga aggatcatgc cttacatgag tacctataag tcgtctaaaa cgcattgcat
    11281 catctttggt tttgtagtcc ggcatattaa ctaagagaac tttattttca tcgccataaa
    11341 gtcctcttgc cacggcttta gccattgcag ttttaccgac ccctgttgat cctgtaaaca
    11401 gagcagttgc ttttggttgc tttcgacctt taaaacgatc aaatccaagc ttcatacgtt
    11461 taaacaacat tgttatagta taaactgcta acggttgtcc ttttatggac tttaattcct
    11521 cttgaagttt ttccatatca aaatcagaat ctagctgaat attatactta ccaaatattt
    11581 gcaatagact ttctcgatta taagcatttc cgtctactcg atcttttgca atcaaatcct
    11641 ccattacagc aattgattta gccggttcgg acaaatcctc acgataaagt ttgtttgctt
    11701 gtacgatttc ttgaagtaat tcatcaggaa tcctttgcga taatctaaaa gaagcctgag
    11761 gatcatcttt aacagaggat gtatttagcc attgtctcaa aatatcgacg acaacatcgc
    11821 tttttagttc attcaattct aacggttgta gccgtctccc taaggcatca tctcttttga
    11881 tatagttttc atattctttt cttgtagtag cggtaatcat ttgaagtgat tcatttgcta
    11941 acggttcttt tagcgaatca cccccaattt tattgccact cccaaaagag ctaacaactt
    12001 tatgaaactc gtcaatgaag aggacaaatt cattatcttt gtcctcagct tttaaaattc
    12061 gctcatattc tttcaatctt ggaattaatg tttctaaacg tgtttggagg acatcatctc
    12121 ccccaacacg caattgtccg attgataatt tatatacttg tactttcttt ccatcttgtc
    12181 gctgtctttc agcccattca cttgcaagtg ctgttttacc tgttccggct tcacctaaca
    12241 agatagcttg cggtgtttcc ggtctattca agatcagtga caactcatgg agttcgtcat
    12301 cacgtcccac taacttatgt tttggtggtt tcattggtgt gagagcatga ttaaattcgg
    12361 tttgaatatt cttaaaaaac tcggtactat tttccatctg tttgtgttca cttcctctaa
    12421 aataagaata atttacttct agtcagtcaa agttaggtac ttaaatgtcg tcttcatgtc
    12481 tccaaaagaa tctttgttaa agtcagcatt tttgtattga tcaatcaatt tttgtgtatc
    12541 attgattgct ttaatttcgg tctccattcg actgtctagt tgacgaatac tttcttgcga
    12601 atctttatcg tcaggatttt gttgtaaacg ttccagatac tcagcttttg tggcttcaat
    12661 tttcttgatg ttagtatttg aagcatttaa ctgatcttct agcttattta caacattatt
    12721 cttacttgta actgctacaa cttttgaata atcaatatcg ccatctttgg taagaaagct
    12781 tccttgatag acattagttg aatctgaata tggatttatt ctgaaattga tattatcagg
    12841 agtattaaca ggttttgctt ttttcccaaa agaaattact ccttcattat taacatcatt
    12901 catagaatat tgagaaagtg cttttgtaac tgaatctgct tcattcacat tgactttggt
    12961 atcatcgtca gctgtatcat caccagaaat tagtgatact tggtttgcaa taaaaacttg
    13021 ataagctctt tcctctaatt taccttttag gaataagaaa gcatccccat cagtacttaa
    13081 catcccatag ctcatttcaa gcttcttagg acgatctttt tcttttgttg ccatatataa
    13141 gttatagttt tttccttgcg tagataacaa ctttctagcg ttttgggagt aaccaagttt
    13201 tactactgtt acatctctat tttgatctgt ccacacatct gaaatagtga tttctgctcc
    13261 tgatcgagca aactccaatg aagaccctat aggtgttgta ttgttcacga gataataatt
    13321 atagtttcct aattgataaa tgtagctacc caagcctgtt aataaaaaaa gcactcctag
    13381 aaaagttgca agcataatgc gtaatccgtg acgtgttctc ttatccttat caccaagcaa
    13441 ccctccaata atactgtatt gatctttggt agatgttgaa ttgacgtttt tttccatcag
    13501 tttgtctgcc cctttcataa aagagcaaac aatcagacgt tttttcggta attctaggtt
    13561 cgggattttg aatcatttcg gtatattctt ccccattaat atttaacaca aaaattatct
    13621 tcctttcttc gttcctttct tttgctcttt attttccaaa taatcaatga tttttgctat
    13681 tgtaccaaga tagtaattcc cctcagcttt gttttttcgg attttgctaa ccattggagt
    13741 aggtacaatc tcttcatctc tcaattcact gaaagatttt ttacctagat attttccaat
    13801 aacagatttt aaaaaacgtt caaaatcttt ctcgtaagtt gttttcttgc cttttagttc
    13861 atggttcata ttgtcaacga cttttgcggt ttcaataatt gttttagttc tcagcttaat
    13921 aatttcatct ggaattttca atcctcgtaa tttcatcgtt gtactaactg gtaacccatg
    13981 ctttactgca tcagcaatac taaaactttt tagatcatct agtaagctct ccatatagtt
    14041 aacaaattca tgccaattaa tagcattcat tgtctcaccc cttcattttt ttaaaatgag
    14101 gttcgggcgt aacacattta tgttattata atatcataat aacataaata aatcaatcag
    14161 caaatttaga tatcccttaa agtatcagca attattcaac aagatattta ttttagctat
    14221 ttcagtcatc ataaaagact aattagcaat aaaataacta atattatcca tttatcagac
    14281 gaaaagaaaa aacttatcta attactctat attaactttt aacaaatagt tgacttgtcc
    14341 aaaaatgtta ccttcaatct cacaaagata ttaagatgtt tcctaccaaa actgatatca
    14401 ccggactttt tattctgtgt tgtccaaaag tgttaccttt agtcgatcaa caaattaaaa
    14461 aaaattgttt ttttcttgac ttgtccaaaa gtgttaccca tagttgttaa aatttgtata
    14521 gattagccat tctttcgaat attatttaga ctgaaacttg cttacaaaaa aacttcttgc
    14581 atttattgtc caaaagtgtt acccatactt ttttaaagaa gcaggttgta ttaaaattac
    14641 aacctgcttc ttctcaatct tcttctaacc aattatgcat tgaaatggtt ggcaagtttg
    14701 attctggctc actaaaagtg aatctgagcc gatcaactct tcttcctttc tttgcataga
    14761 ttttttcata atcaaaagtt tcaaatacct gtattccgtt ttcatcagga gctaaaaatt
    14821 cttctttcgc ctgctctagt attcttttgt caatatttgt cattctataa cttgaaggta
    14881 tacttaatgc tcttctaaaa tcttcaactt tgactaccca ataaccattt cgccactctt
    14941 tatttctgta ttgcatgaga tgacgataca attcttttgt gtagctactt cttagttttg
    15001 taaaattatc aagttcaaaa cgagtaaagt ttttgccaat tgagtttaag ataaattcaa
    15061 attcctcatt tgccttaatt gtaactgttt ccttctgttt atctatccgg aatttttgaa
    15121 aaagccacag ctgttcatag acgtctgaat cttcaaaacg gtaggttaaa gtacctagtt
    15181 tgtcactcaa agcttttaac acagaataaa aactgtcctt ttctcttctg tcgtatttga
    15241 ccaaataacg aaagaggttg aaatcaaaag ttacttctgc tgttccttga cgtttcattt
    15301 ttgataaaat agcccaaaac acatccattt caacaggctt aaatcctcgc aaagctgttg
    15361 tattcagacc attgttataa cgcacaattg catttgtttg ttctgatact aaatctacat
    15421 cactatcaat aatcttttcg gtaacttctt gagacattga ttactctcca atcttctttt
    15481 tgcgctcctt taatcatgtt aatctggtac taattaaagg aaacaatttt ttctgcttgt
    15541 tacctaaatt aaatcacaac taaaggtaac agtcaacaaa gatttgttac taatctaatt
    15601 ttctattttt tcgccttcca aatcaagaaa accgaaggta acgtcttatc ctagtgtgat
    15661 acctcaaatg tccacttttg ttacctttgc tgtccaaaag tgttaccctt actgtccact
    15721 tttgttacct ttactgtcca aaagtgttac ctttataccc ctttaatact tactctccca
    15781 agagattaag cctcccctaa cagatatatt aacagatatt taacagatat attaacagat
    15841 atttaataaa ggaggattac tcctctctta tttcaaaatc ttaaaaataa aaaatcttaa
    15901 aaaaaactaa cactatctag gagtttattt tgcttgtgta actttgaata attgaaaaaa
    15961 aggaaaagga ggaagcttca gcttcccctt ttatttatat ttataatata tattttaatc
    16021 tttaaaactt tagcaacctt caaaaaggct ttatatcaat cttaaataga ttttagggtg
    16081 gacataaagc gatgcgaaca tggacaaaaa gcgatgtgaa tgtggacaaa aagcgatgca
    16141 aacgtggaca aaaagcgatg tggtattccg aatatatcca aaaaaagaaa aagtatgtga
    16201 atttatttct aaaaactaga aaaatatttg ttttttaatt ttggtaattt ttataatttc
    16261 gtattttttt gaaaaggatt tttatattga aaatgttcta aaatagcgat ttctgctgtc
    16321 ttatcaatga aaattgatta aaaaaataaa atgtgtttta cagagattga gttatgttat
    16381 aaatttacga tacatttctt attgtatcgt atcgaaaaca ggtctatact tattcaatgg
    16441 aatcgtacca gttccaaatt tttaagctcg taccaagctt agaaagaaga ggcaatcgta
    16501 tgaaaataac agaaaagaat gtaaacccga aatttgaacc taccgaaagc aatctaaaaa
    16561 agtttgattt aactgttact ttatcgaatg aacttgtaga cagcattgtt gaaatggatg
    16621 ctatgccaca aaaaatttat ctttatgcta taggacatct tgaccctaaa aatccgcctt
    16681 ttaataatac tgttaaagta tctaaaaagg ctttatttgc gttgatgtct tctagttcat
    16741 cttcttcaaa acattcaaga ttaaaacaag ttattgaaaa attgcatcag caatctgtca
    16801 ttaaaattca aagaactaaa cctaacggta agactgaata caaagtcatc tcaccgctag
    16861 aaattactga attcaatgat ttttctgatg cagtatctat taaatttagt agttcaatta
    16921 tgcctttatt aacgaactta gaagatcatt ttacgcaata tgcatttgat caagtagtta
    16981 acttgacaag caagtatgcg atcagttttt ttcaattatt cactaaagat tttaatctgt
    17041 atttagcaaa tagagataac ttaacatgga gtacaaaatc acttgataga ttaaaaaatc
    17101 ctgttttctc cattgcagat ttacgaaaga aatttagtat tgagaaaaaa tataaagctt
    17161 ttcgagactt tgaaagacgt gtaattaaag aaccgattgc ccaactgaat aaatacactg
    17221 attttaaaat tgactatgag cttatcaaga aggggcatac ttatacaaat ataaagttct
    17281 tgcttacacg taccatgtca gttccggtac cttataagca agaacaaaga gaccctgctt
    17341 atttaaaagg cgcagaagat aaaacagaga aaatgaatca atcgtacttg aaagctatga
    17401 atagcaaata cactaaatta ctaatcaaaa actttttgat cagttctgcc gacttatgcg
    17461 atcttaaact tatgagccga cttcagaata aagtttatcc gctttatgat cgtttatcca
    17521 aagatagagg atttgaatca gttgtcaatc acctatctta cgttgctact cataaggagg
    17581 attacacaat aaaaaatact gttaaatatc tcgaaaaatc aattacgagt tatttgcctt
    17641 atgtgaacct ttatgattaa caactgaaaa aatgcgtgaa ggaaggaaaa acttttgaaa
    17701 aaagatgaac tgacaaagta caatgaggag ttcttagcaa caattgacat gaaaatggat
    17761 ttaaagtcgt atgaacttta tcaattgctg ttcagttata tctcacccac aaagctaaag
    17821 aaaacaggcg tagtagattt acctgttaaa gcgattatta attacatgga tgttgatcaa
    17881 aatcttgaaa cggaactaaa aaccatagtt aacactttgc aaagacaagc agtttatgaa
    17941 atttcgaatc tagacaaaaa atataagacg tatactactg tatctgctat tgatcggatt
    18001 cattgggatt tagaagagca tagtgtatct ttcagttttt cagaagatgt aattccctta
    18061 attgtctcaa tcaaaaagaa gtatccgttc tttgtttttg aagacttagc atcttttcaa
    18121 aaaaaatata gcatcgtgtt atacaaatat ttggcgatgt attataaaaa atatcttatc
    18181 gccaaaaata aaggagattt tgagaaagct gaaatatata agaatcccct gattgaaata
    18241 gttaaaattc gtgagattac gaaaacagaa aatgagtata aaacaatatc gaattttgat
    18301 agacgtgttt taagggaatc agttgaggaa attaatgaaa aatcaatgct gaatattgat
    18361 tttgctaaag ttagaaaagg cagaaattac aattttgctg tccagtttaa tatttctagt
    18421 gagtttgatg aaaaaactta tagagaaaaa aaattaggtt aatgcaaaat atatcttact
    18481 cgtttgaaga tgcttcagac gtatgctaag atatatagtg ccttgggagc aaggtattaa
    18541 tctcctttag aggttaatta gcttgtgatc gcctatcaat ttttttggta ggcgattctt
    18601 ttttttgaaa caaaaaagca aaaattattt tttaattaga gaggtgcaat gcgatgaaat
    18661 actttttttg tgcagtattc gaatggaaag gaaatgaata tgcagttaaa ttcccagatt
    18721 ttccagactt atatacacat ggtgaaactt tagaagatgc ttttgagatg gcgcaagaag
    18781 tattggaagg atacttggtg cttttagagt tgcaagaaaa agaaattcca tcgcctacgc
    18841 ctgttcaaga gttaaatgca agaatcaagc gatctgagaa tgttaattta tttgtcgtaa
    18901 aagctaatac gaaagttgct aaagctcgaa acaagcaaaa ttatgatcga aaatcagtga
    18961 ctgtggaaca ctatttaaat gttttagcgg ctgaagagaa tattaatctg tcgaaagctt
    19021 tgaatgattt gttgagagaa aagttgattt gatgtctctc agatgatcat attaagcaaa
    19081 aacagcttgt tttaggacgt atggatttaa gaaagacaaa ttatcaaaga atatattaaa
    19141 agctctcaga agccttctga gagcttttaa attgctatgt attgtactgc atctgctcaa
    19201 attgattttc ttttcatgct taccatgtat ctaattttcc atcaagtaat ttttagatat
    19261 gtattgagta ataaatagca aatttgcttg atataagctc gaattaggtg ctttgtaatg
    19321 tgttaggata aaattataca agaaaatgtc aaaagctctc agaacgcttc tgagagcttt
    19381 ttatcggtag gcttgtttaa cgtgatcttg aaggataccc ttttgatgtt tctctcgatc
    19441 cctgcatcgc taattactaa gtgttcttca agtgtgatgt aggtatataa attaagcatc
    19501 aaaatggtgt agataagcaa aaaactccct aaaactaagt gttgattata aaaatctgac
    19561 ttataaaaaa gaactgagaa tgttagtgtt gattcccaaa aaagaaacaa aattttgtat
    19621 ttccaaagat agtggatcaa gcgctgtgct ttacccatct caaataattt ataataacct
    19681 gctaattgat cagcaagcgt atcgttaacg gtttctgttt gtgtttgttt catctttctc
    19741 ttctcctgtt tcaattaatc taaaatttca gattgagcaa gcaactcatt gtggtagtcg
    19801 gtttgaaatt caaataacaa ttttgccttc ttaacgaggt ttaaagcgtt cgttagtgat
    19861 tcacttaatg cttcaacatc tttaactgat tttgcatgtt tcattttttc agtgtgcgta
    19921 tagcagaatt caggtattga gttaggggtt gcctgttcaa taaacatctc aattcgcaag
    19981 ttattatcct caaaaataat tagatcattg gcaaagtgtt tggtactaac gctaatgcca
    20041 gttgtatctt ttaatagatt attgattaac gttcgagaga aatagtttaa gtgtgtagct
    20101 ttcataggtt cggtctcctt tttacttttc aagcaactct tcttccagtg ctttttgaag
    20161 tagttgagag aagtttatgt ttttctcctt ccctaaaaga actaaccatt ccggaacact
    20221 aacatttttt ctaattgttt ttgtatttaa gcttcttcgg aaaagtttaa tgtttagttg
    20281 gatgattact accacttggt tggctttcaa agttaattct tccactgctg atggtttagg
    20341 aaattctgca tctggtacac tatatagcgc taatcctaaa gcatccttag cgtttaaata
    20401 tgcttcttca agactatttc caaaggtaga tatttccggt aagtcaggga aaacgatgtt
    20461 ataagcttct ccttctttct cgaagattgc cggataaaaa atattttttg tcttcatttc
    20521 ctcgctcctt ttctagtgta agagaggata gtatgcctaa taccaaatag gaaggcaagg
    20581 ctgttaaagc cctgcttgct tccagatatt agcttctgtt cctagtggta catcaccatt
    20641 gtggatcgga acaacgaccg ttcttttagt cttggaatta taaaattttg catgactgcc
    20701 agtttgtcca gtctttttga agccgttaga tttgagaatt tttacaattt ctcttgctgt
    20761 cttaggcata gctaccctcc ctttacaaaa tctattatac acattgttgt gtatggaatc
    20821 aatagaaaaa gaggatgttt tattgcaaaa ctaataaaat gatttattgg ttttttcagc
    20881 aaattgaatg ttattagcgt tgcaaatatt catgatttcc caagtatcat cagaagtata
    20941 ggtatctaag aattcattga cagttacggt tgattcgtat ggttcataag tcaaagcgtt
    21001 ctccaagtct tttgatgaaa taatcaagac tttttcaatt tcctcccctt cttcatctat
    21061 gaaaacatat tctaaagtga tttgttcttc atcggtataa ttcatattgt gttctccttt
    21121 cttgtactaa gaaaaatgga tatttccaat tgcatcccac tcggcaccat tgtggtatag
    21181 gacgtgaccg agcgttacgc ctttgaaatg ttcttctaaa tacatccaaa cgcattcaag
    21241 gctagtacct gctttgagat tgtagaagtc tgcatccaat accttttcag aagttatcgg
    21301 atcaatgcga gttggtactt caataaattc agtccaaatt tctgcaaaag tcttaccttc
    21361 caaagtccac actccctatc aattaattcc aaaagcaaat agagaaatca agcgaccgtc
    21421 aatagtcact tcaacaactg aaaatgccgt tgaaacagtt ttaacatcta cactttccaa
    21481 gttcccgatg aaggaatctt tgtgctttag aatagctttc tttagctgtc tgttatacac
    21541 ttgccgactg ttaaactttt tgaattctcg atccttgatc agctgtttaa cgatccctgc
    21601 attaattgta taactttctg caatagcaac gtgagtaggt tgctgtaaag tagctgttag
    21661 catcttgtca ctccttccta aaagttaatt agcttgttta caaatacatt atacacatcg
    21721 gtgtgtataa tgtaaagaga aaaaggtgct aatggatcag ctgttctaaa caaaagaaaa
    21781 cgataaagta acaaataaag tcagcaaagt taaaaaggat gaaacggcta gtccggttgc
    21841 tttgcttgtg tgattttcgg ctttcttata gatcaaatag gaaattatca gtgatattcc
    21901 agtaaagaat aatgtactag ctgtcactaa aagaaatagg ttaatcatac gatacactcc
    21961 ttctgtaata ttggtatcag atacgtttaa atgcgtttct gagctgtttt ggatcagatg
    22021 gtgatgtttt tagccctacc ctaaaaacaa agcccagaaa agaatttaaa agcgttcgta
    22081 cctaatacgt ttatattcat atacatatac ataaacataa acgtgtatac gtttatgttt
    22141 atgtatttaa gttttaggct acttccttaa catctcctgc tgatagtcga gtgaaccgag
    22201 tgagtgatcc atcttgtagt cgaaaaataa agctacgttt gagtttatac tgatagacag
    22261 cgacatacga tccatcccag attgagtaag ttttacctgc aactaataag tcatcaagtt
    22321 ttggtttatt gctttcttct ttaattctat ctagttgtcg cttaaccatt ttttcttgat
    22381 caccgacaaa gaatttcaac cattttttcg gaattttctt aaagtaagca ggactgtcat
    22441 ttaagaagta gattggtttg tacatttcat ctcgaaagat gaagctgtca atatcgtagg
    22501 ttccttctgc atctttgaaa aggataattc catagatctt cgttactttg gtatctacga
    22561 tttccaaacc atttttggcg taccctttct tttcttcgat cacttcattt gctgatgaat
    22621 aatcaccata ccatcccata aaaaatcgct ccttttgaaa gttaattagc ttgtttacac
    22681 ttatattata cacaccggtg tgtataatat caagaggata ttgttctttt ttaggtaaag
    22741 tgggatcgta aacagtgatt ttgttgggtt aacaaaaaaa cagacaagcc ttatcagctt
    22801 gtctgttact tataaacttc acttctgtga ccaatagaca atataagaat tgtcacttca
    22861 tgctcgctaa tatcagctat tatacgatat gcacctaccc tatatcgcca gtagcctgat
    22921 ttattagctg ttagaccttt accatgcttt cttggatcat cagtgcctac aagatttttc
    22981 tcgatccagt ttaggataac ctttgcctga aacttatcca ttttttttag cgctttttga
    23041 gcttcacgtt catatcttac ttggtaagtc atcttataag cctaactctt ttagcatatc
    23101 ttcgtgggaa atactttgat cgttttcctc atgctctttc attagttgct tgtaggtggc
    23161 aaagtctact aacgtttctg ctgtttgcag ggaattacta cgcataaatt cagaaatgtt
    23221 atctccgttg aattcagcaa ctttttcaag aaaatctttt tcttctttag atacacgaat
    23281 acttattact ggcatagttt atcaactcct tttcaattac attgtactac gattgtatga
    23341 caaatgcaat agttatatat ttgaatatat acataaacat aaacatatac atatatatgt
    23401 ttatgttgta gaatataaaa gcaaatataa atataaacac gtttatgtat ataaacatat
    23461 acataaacgt gtttatagtg tataatggag ttacaaaagg ttaataaggg aggtttaatc
    23521 atggaaaaga agttgtcaat cattactgga aacattgaaa aaggtggaac aggtaaaaca
    23581 acaacaatct acaatctagg tggatatgct gtcgaaaatt taggtatgaa ggtgctgtat
    23641 attgatgaag ataagtcgca aaacctatca aaacgatttc ctgatgcttt cagtaaagcg
    23701 aaaagagaga atacaatcaa tcatttatat cttcatggat cagctgaacc tttagctata
    23761 aatgagaaca tggatatttt agtagcaggt gaagatttaa aacaagttga gatgcaaatg
    23821 cgtgatatgc ctaacaacag aaccctactg tttagatgga tcgttgttaa ctatgaacag
    23881 cttaaagaga agtatgatct aattctgatt gatactcata atgatgcagg tctactagct
    23941 caaaatgctt gggctgtatc tgatcttgtc gtaggcattt ctgatccatc taaagatggt
    24001 tttgaagctt tgctgaagct tggtaaagat attgatgcac tagcaaaaca gttgattgat
    24061 attaagactg gtgaaacact gatggaaact aaatacgcta cgatcggtag caggatcaaa
    24121 cataatacta attcaagtcg tgagttccta gaattggtac caacgttatc taattatctt
    24181 ggatatgtac aagagaagga attgcttaat gcaactagct tagaaggtaa gaatattgct
    24241 gagttcgcta aggataagaa tatctatcgt aagaataagg atttctttga aagcacgttt
    24301 acgctataca acaaaataat tgatacggca caagaataag gagtgattga agtgaaagaa
    24361 aatagattta aaaaattcgc tgaagctgaa gtagaagaag ttcctgaagt ggttgaagca
    24421 gttgaagaac ctaaacaaac acctaaagaa acaacaagtt ctttggtagc taaactaaaa
    24481 agtgatagtt ctgaaaagaa gaaaaattat caattcacgc ttcaaccatc acaaagaaag
    24541 aaattatcta aaatcagcga aaagttagga attcgatcag attcagcttt acttggtgaa
    24601 atgatagata acttgtatga tgaagttttt ggtgagtgat cagtttaaag ctgatcactt
    24661 tttttattgg aataagcggt taggtatagc ttaactaaat ttcgtatacg tgtttatgga
    24721 tatatacgta tacatgttta tatacatgta tacgtatatg tttatgtttg tatttgtaca
    24781 taataaaaag gctaggtatt gtaacctcgc ctttttattt ttaaagtaag tctttgttac
    24841 ttggtgcatt gaaccctttt agcattggct tttctttctt tgctgaatga tcggatgtaa
    24901 ccgttgaagg atgctcttgt tgaatagggt tatgatcagt tggtttcttc tttacttctg
    24961 ctactttgct atcgtttcta tcgttgcctg cttcaataat tgtaacttca ttgttcttta
    25021 cacgccgata taggttcaaa gcttttttga tcgtctgaga gtatttaacg cctagtgttt
    25081 catattcgga ttcaagaaac tctgctaaag gtaactcgct aaccttttct ctattgatta
    25141 taactacata acgctctgat tttcccttat tcatgttgat ctccttcgct gttttattga
    25201 gttaaaccaa acttgtaaaa gccttttaca ttagaaaatt cactgtcttc aacaaacaag
    25261 gtatgcggaa ttttatcttt tacaagttgt ttgtcgataa tagaagctcc accaccagta
    25321 aagacaactt tatctaaggt tgtgaagttt ttgaatgtag ctaaaacttc tgcaacaacc
    25381 atattggtgt atgtttttat ttctctttca actacttctg aaatatcaaa actttcattt
    25441 ccgcttggct taaatagata tacgcctttt tctttgcctt ctcggataat cttttcaagt
    25501 tggaaagcat taggactgat cggaaggtca agcatattta cgatacgatt atataaagta
    25561 aaaatgccgg tatccttttg ttcacgattg ttttcgtcaa tttcaaaatt ttggacaaca
    25621 tcaaaaagtt tcgtgccacc accaatatca acaaaaccga tcttctgact gatcaatgtt
    25681 tcatcttgta cactaccatc atcagcaagt aggaggttat atagtgttcc aatcggctgt
    25741 ggcagtaccc aaacggtatc tacgtttata ttataagcct taccgtcaac ttcaactgaa
    25801 tgttgtcgtg tggcttgttg catcacgtat ttgacgattg tttcggtata gtcggatgaa
    25861 ggcagaccta aaactagatt aacggttaaa acgtcatcag attgatcttc taaacgtgct
    25921 aggttagcta aagagaaaga taggatattt ttgtaggttt cctgcttgta tctgctgatc
    25981 ccaaaaccta gtgattctat cacgtagtca tcttttccta gctcgtgtat atccttccca
    26041 aaataatagc tttcagtagt gtttactagg ctatattcag aaacgtttag tgatcgtttt
    26101 aatgaggaac ctatattaga aaaacgtcct gaattaatga tatttttgtt caaaatacga
    26161 gagggaagtg agagtggaga aacgtgtgta ctcatttctt ttactgattt attccctaag
    26221 tcaacggaaa acaataatgg ttctttcatg gtatgacctc tttctgtttg tgtttatggt
    26281 atttcggtac gaaaatagtt tacacctatt tactattagt tgcaactgtt tataagaaaa
    26341 aaatgcaatc ataaaagtct aattaattat aataaagtgt aaataaaaag gtgtaaataa
    26401 atgcttgcaa atttatctta ttatgatatt ataaaatcat aaattatatt aaggagtgat
    26461 cctgatgcga ttgagaagaa ataagaatta cactaccatt attttagaag attttactga
    26521 tcaagaatta cttattgtcg gtaaaacaaa agcagatttt atcgaaaagg gaaatgcttc
    26581 aatagtaaaa gcttcaaagg ttgctgtcga aaaatatttt gattctttag aagaaagtgc
    26641 taaggaaatt tttaatggag agaaagctgg tagctatgag ttagacggta ttagatttag
    26701 cttgatccca acaactgaaa atattattcc gaagaaatta tattatatct tttcatctga
    26761 aaaacatact tcaatgaagc cttgtatttt tgattggcaa tggttgattg atgctgtatt
    26821 ggatgtaaaa tgttcaaaat acaatattac tttggggtgt taattatgag tatgctagtt
    26881 agaaaattac cattatctgt aagagaattt ctattttact tggtctgctt aatcgcatca
    26941 gggtttaagc tgatcgaaca tatttttatc tttgcttatg tattagcaat gatcgcattt
    27001 ttatctggcg gttggttaat tatttatttg ttaagctaag ttttagatca aaaataatta
    27061 gtaaattaaa cgataaaata accgttaata aatgtaatga aaggacaacg cctaacaatc
    27121 agcttgtaat aagattataa aataacataa tatcaaaaat agtgcttttt aaaggacaaa
    27181 ttaagtgtat caacataaac gtgtatatgt atatgtttat gttgatactt tttttgtctt
    27241 aattttttat ttttaaaatt ctatttacta atgctgtata gatagtgatc agaaaaaaca
    27301 aaatagcgag attaagctat ttattagttc atatattata ttcagattaa tatgatccag
    27361 tattaatctg aaggcaaaac caatatattt ctacggactc ttgtaaaact atttaaattt
    27421 tcctgctaat aaaataacga aaatagaata tttagctttt ttataccatt ttacgataac
    27481 atgatttcat ttgtaatatt aaaacattta aatttttaat tattctttca aattagatca
    27541 attaatatcc ttataaaaga gcataataaa tggtttttac atcgttattt attgatatta
    27601 atctcatcca aaaaaatgaa aacgcatact tttatgggtg attgaatgtg attttaatac
    27661 atataccaat taaaagaaaa ctttttagat ttttacttac aaatttataa aaaaacaaga
    27721 taattgatac tttgattttg cgaacatttt atcttgccgc ctaattcagc tttaatatca
    27781 tgattatatc agtaacaaat cgctttttta gctaatttaa gcatcaaata attattctta
    27841 atcagggaaa aaataactaa taaatggatt ttgggaatag gtaaaaactt gatcggtttc
    27901 tggctaaaaa taacgtgaaa aaggaaatat aaaataacat ggagcgtggg aggaataaag
    27961 aaattttaca cgaaaggtgc gcagggatgt aaagaaactt aacacgaaac aaaagt
//
LOCUS       DACCVZ010000031        27792 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.031, whole genome shotgun sequence.
ACCESSION   DACCVZ010000031 DACCVZ010000000
VERSION     DACCVZ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27792
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.031"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(313..2205)
                     /locus_tag="IVW63_001376"
     CDS             complement(313..2205)
                     /locus_tag="IVW63_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7859658.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2202..3929)
                     /locus_tag="IVW63_001377"
     CDS             complement(2202..3929)
                     /locus_tag="IVW63_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7859659.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3945..4595)
                     /locus_tag="IVW63_001378"
     CDS             complement(3945..4595)
                     /locus_tag="IVW63_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7859660.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4799..5095
                     /locus_tag="IVW63_001379"
     CDS             4799..5095
                     /locus_tag="IVW63_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP7859661.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5287..5907
                     /locus_tag="IVW63_001380"
     CDS             5287..5907
                     /locus_tag="IVW63_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAP7859662.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5999..7165)
                     /locus_tag="IVW63_001381"
     CDS             complement(5999..7165)
                     /locus_tag="IVW63_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP7859663.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7177..7530)
                     /locus_tag="IVW63_001382"
     CDS             complement(7177..7530)
                     /locus_tag="IVW63_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAP7859664.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7658..8680
                     /locus_tag="IVW63_001383"
     CDS             7658..8680
                     /locus_tag="IVW63_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HAP7859665.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            complement(9119..9553)
                     /locus_tag="IVW63_001384"
     CDS             complement(9119..9553)
                     /locus_tag="IVW63_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859666.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9663..11522)
                     /locus_tag="IVW63_001385"
     CDS             complement(9663..11522)
                     /locus_tag="IVW63_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP7859667.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11640..12800)
                     /locus_tag="IVW63_001386"
     CDS             complement(11640..12800)
                     /locus_tag="IVW63_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HAP7859668.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13107..14531)
                     /gene="araA"
                     /locus_tag="IVW63_001387"
     CDS             complement(13107..14531)
                     /gene="araA"
                     /locus_tag="IVW63_001387"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HAP7859669.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14547..15245)
                     /locus_tag="IVW63_001388"
     CDS             complement(14547..15245)
                     /locus_tag="IVW63_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAP7859670.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15202..16863)
                     /locus_tag="IVW63_001389"
     CDS             complement(15202..16863)
                     /locus_tag="IVW63_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAP7859671.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17081..18481
                     /locus_tag="IVW63_001390"
     CDS             17081..18481
                     /locus_tag="IVW63_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAP7859672.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18733..19812)
                     /locus_tag="IVW63_001391"
     CDS             complement(18733..19812)
                     /locus_tag="IVW63_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7859673.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19898..20857)
                     /locus_tag="IVW63_001392"
     CDS             complement(19898..20857)
                     /locus_tag="IVW63_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HAP7859674.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20869..22392)
                     /locus_tag="IVW63_001393"
     CDS             complement(20869..22392)
                     /locus_tag="IVW63_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAP7859675.1"
                     /translation="MDEEVKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHE
                     TADGDGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIE
                     PNSFGLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQ
                     KKPFGVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPR
                     LPSYPEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFD
                     RQIEEIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMED
                     TLLFGSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAK
                     GQVLKQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLL
                     DQGEHYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22402..22966)
                     /locus_tag="IVW63_001394"
                     /pseudo
     CDS             complement(22402..22966)
                     /locus_tag="IVW63_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
     gene            complement(22972..23835)
                     /locus_tag="IVW63_001395"
     CDS             complement(22972..23835)
                     /locus_tag="IVW63_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7859676.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23849..24745)
                     /locus_tag="IVW63_001396"
     CDS             complement(23849..24745)
                     /locus_tag="IVW63_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7859677.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24920..26191)
                     /locus_tag="IVW63_001397"
     CDS             complement(24920..26191)
                     /locus_tag="IVW63_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7859678.1"
                     /translation="MKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTLTFWNGF
                     TASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFIALNYPD
                     FAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMYMYWNND
                     LFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLANGGKLV
                     NDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIEINGPWL
                     NNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFLKYWNTT
                     EIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQISAINNDI
                     INPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26181..27698)
                     /locus_tag="IVW63_001398"
     CDS             complement(26181..27698)
                     /locus_tag="IVW63_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAP7859679.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
BASE COUNT         8114 a         5856 c         4816 g         9006 t
ORIGIN      
        1 caagaggttg tgagcctgcc gtttaactcc gagtcacaag gagcaatttc aaaaaacagc
       61 ttctcaggtt tgttgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
      121 aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagatacaa aacggaaaaa
      181 tagcttctca tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacaccg
      241 tttattcgga aaaagggact gtgacacgac ttttgtcaca gcccctaaaa aaaataataa
      301 atttgtacta ttctatgaag cttcttcttc agaaaactga ctgttataaa gatctgcata
      361 gaatccgtct ttttccatca atgtatcgtg gtttcctgtt tctacgatcg aaccatgatt
      421 catcacaata atgttgtctg catcgcgtat tgtagacaag cggtgagcaa caacgaaact
      481 tgtccggttt tccaataggc ggttcatcgc tttttgaatc agtatttctg ttcgtgtatc
      541 tacactagat gttgcttcat caaggatcag gacatctgga tttgctaaga atgcccgcgc
      601 aattgtgatt agctgacgct gcccttgcga aatattgctt gcatcctcgt ttaatacagt
      661 gttatatcct tctggcaatt tacgaacaaa atcgtctacg tgagcagctt tagcagcctc
      721 aatgatttgt tcgtctgttg catcgtcgtt cccatatttg atattgtcat agatacttcc
      781 tgtaaacagc caagtatctt gcagtaccat tgaaaactgt gcgcgcaatt catcacgtga
      841 aagatcacgg gtatctacac catcgtaacg aatactacct ccagaaacat cgtagaaccg
      901 ttcaagaagg ttgatcagtg tcgtcttccc tgcaccagtc ggacctacaa tagcgaccat
      961 ctcaccaggt ttgacatcca agttaaaatc agtcattagc aagttatctg gtgtgtagcc
     1021 gaattgaaca ttttcaaaac gaactttgta tggtgtatct ttttcttctg gaaggccaga
     1081 tttttcattg gacatctctt cttcatccaa cacttcaaat acccgttcgg ctgaagcaac
     1141 tgttgattgg atagtgttca tcaaacttgc aagttgagtg attggttgag agaactgtgt
     1201 tgtatattgc aagaacgctt gaacatcccc taatgtcatg ttcccatttg caacttttac
     1261 tccgcctagt acagcgacga acacatagcc tagattttta acgaaattca tcaacggcat
     1321 gatgattgcc gaaataaatt gagctttcca accagcggca tacagattct gattttcttt
     1381 ttcaaatact tcctggtctt tttcagtatg attgaatgtt ttaacaatgg tatgaccacc
     1441 atatgtttct tctacttggt tattcaataa acctaaactt ttttgctgat ctgcgaaaaa
     1501 cacttgtgat ttcggcgcta cgatcatcac gatgatcaag cttaaaggga tcatcaataa
     1561 cgcgactaac gtcaattgcc agctgattga aagcatcatc acgatgaccc caatcaatgt
     1621 gactgcacta gttacaaatt gagtcaaatt ttgctgcagc gtgcttgcga tgttatccat
     1681 atcattgatt gctcgagaca tgatatcccc atttgtatgt gtatcataat aggaaatcgg
     1741 tacacgattc attttggctt ccaaatcatg acgtaattca taaactgttc gttgggaaac
     1801 acgtgtcata ataaattgct gtaaaaagtt gaatacagca gaaatcaaat acatcacgat
     1861 tactgtcgca atgatctgcg cgattttatc aaagtctatc ggaaattttg ttacttgttg
     1921 gccttgttgc atctgttgag cgccagccat tacacctttg aatatttctg tggttgcttt
     1981 ccccaagacc tttggtgttt ggatttggaa gatcacggct gctattgcta gtacaaatac
     2041 agcgatgatc gcaaccatac gtttagacat atagccaaac aatcggcgta ccgttcccca
     2101 gaaattttta ggcttttcac cttttacacc gagatttctg ccaggtccac catgtcctgg
     2161 accgcctgct ggtccatgag agggacgtgt gtttgtttta ctcatgctaa gtcctcctct
     2221 cttagttgtg aatgaacgat ttcttgataa gtttcgtttg ttgctaatag ttcttcatgt
     2281 gttcctttgc caaccagttt tccttcatct agcacaagga tcatatctgc atccattact
     2341 gtacttactc gttgagcaac taaaacggtg atactttctt tcatattcgt tttcaatgct
     2401 tggcgaagat tggcatccgt tttgaaatcc aacgctgaga aggaatcatc aaacacatag
     2461 atatctgctg ttttgactaa tgcccgtgca attgccagac gctgtctttg tccaccagag
     2521 aagtttcctc ctccttgttc cacatggcta tctaagccat cttccatctc tgaaacaaaa
     2581 tctttagctt gtgcgatttc taatgctttc caaatcattt catctgttgc atccggctta
     2641 ccatactgca tattgtctcg gatcgttcca gagaacagaa ctgctttttg aggaacaaag
     2701 cccattaatt ctcgcaaatt atattgagtc atgtcactaa tgtccgttcc atttatttgg
     2761 atcgaaccag attcgatgtc atataatcga gggatcaaat tgactaaggt cgttttacct
     2821 gaaccagtcc cccctatgat tgcgacgatc tcgcccgact tggcttggaa atcaatatct
     2881 tccaatgcaa gtttttctgc tccatgatat cgataattga catgattgaa ggccaatgtt
     2941 gcgttttttc cagcaaaaga aactgtttta ggattttcag ggtcatggat accgattttt
     3001 tcatccaaca cttcattaat acggtcagct gaagcttgtg cacgaggcac catgataaaa
     3061 atagcggaaa gcatcataaa gctgatcaag atctgcatcg cataagtcat aaatgcaatc
     3121 agattaccga cttccaaagt catatctgct atgtagtgtc caccaaacca agtgattgct
     3181 acgtttgtac cgctcatgat caatgtcatc attggcatca tcaatgcgac gatcgtatta
     3241 actttgattg ccgtatttgt ataatcttta ttcgctaaat caaaacgatt ttcttcaaag
     3301 cgtgtcttat cgaatgctcg aatcactctg acccctgtca atccttctcg aaataccagg
     3361 tttaaacggt cagttttctt ttgcatactt ttgaataatg gaacagcaaa gtacatgatt
     3421 ccgccgatca aaataatcat tactgggatg acaactaaga agatttttgt caactgatga
     3481 tctttttgat aagcaagtat gctcgcgcca atcaacgtga ttggtgcatt gatcatcata
     3541 cgtaaaaaca tttgtgtaac catttggatt tgagtcacat cattggtcgt tcttgtgatc
     3601 aaagaggccg ttccatattt atcaaacgca tcttttgtca gactctctga ttttttatag
     3661 acatccgtac gcaattgctt acccagtttc tgtgattcac gagtagcaaa aaatgtattt
     3721 gcgatagcag ctaagatact gatcaaagaa aagccgatca tcacaaaacc tgtatgccaa
     3781 atataatcga catctccttg cgctacccct ttatcaataa tattggaggt aagtgtcggc
     3841 aaatataaat ctgccagtac ttggatcacc atgaaaactg cagctgcaat tgctgaagtc
     3901 aaggagatcc gttttacgat ttttagcatc tagttccctt ctttctattt atatactccg
     3961 tttttcagcc aagaaagttt caaattgaat tcactgattg cttgctctac tgagtaatct
     4021 tcagatgttg aaaataagcg atacgaatgc gcaattgttg taaatacagt attcatcact
     4081 aattggatca gtaattccaa ttcatgatca ttttttactt tcagcttcgt ccgatcgatc
     4141 aattcaagca actcttttgc atcttgtttg tgttctttat gtggatcgtg aggcgttttt
     4201 tggcgactcg tatgaggagc gacttttctt gaggcacggt aatccatgtt cataaacaag
     4261 ttacgataaa aagaagcatt ctcgccttcc aaaatctcat aaatcatttt agaaaaatag
     4321 gattcgaatc ctttgaatag atcaccatcg gattctttca ttagttgtaa catatcttta
     4381 gagctgtcac gtctcattgt ctcaaagtaa taaaaataaa gatcctcttt atcttcaaaa
     4441 tactgataga aactgcctct agggatatcc gctaatttga cgatattagc aatcgaagct
     4501 tcttttaagg gtactctaga aaactcgatt ctcgcagcct cgattagtct tttttgtttt
     4561 tctttaggca aatggaaaaa tgtctgtgtc ggcatatgga ttctcctttc tttcaagatg
     4621 acacattgtc atatgacgct atgtcattat aacacctcct acctgttttg caagacattt
     4681 gcatagtttt tttcattatc atccgataca ttaaaaaagt gataagagga atccttccat
     4741 ttgaattaat gagagttgcc cattaaaata gccacatact aaacaaagga tgagataaat
     4801 ggcccaatca attagtgtcc aagacttcaa taaattgcct ctcgatgctg acagcatcgt
     4861 tttagataca agaaatacct tagattacac aaaaaaccac ttaagccact cgctttctat
     4921 ccccgctgct atcttgccaa gacaattaaa aaatctagat ccaaagaaac tttattatat
     4981 tctaagctat acaggcaggc gatcagaagc attagccgat caacttactg ctaatggttt
     5041 tcgtgctgtt tatatcattg gtgggatgga agctcttcag tcgagtgttg cttgaatatt
     5101 gcttgttaga ttcaaaagag gctgtgacaa aaaatcgtgt cacagcctct tttataccct
     5161 gtcttttttt agttatttat tcttcaacct tatcaatatg acttgatagc cttttctttt
     5221 tcgagtaaac tgattttgtt agtcatagtt ataacaatca tagcaataaa aggagaaggt
     5281 aagcatatgg catctgtttt agtagtcaaa ggtcatcccc taactgcaga agaatcgcgc
     5341 acagttaagg cattgacgtc ttttttaaca agttataaag aaaatcatcc agatgatgaa
     5401 gtgactgttt tggaacttta tcgcgatgat attccggaaa tcgatgaaga attattatca
     5461 ggttgggaag cattacgtgc tggtgcagaa ttcacttcct tatcagaaag tcaacaacaa
     5521 aaaattgctc gtttcaatga attgactgat cagttccttg ctgctgataa aatcgttatc
     5581 gcaaacgcct tatggaatct aaatatccca acaaaattaa aagcttggtt cgataccgtc
     5641 aatgtagctg gaaaaacgtt ccgctataca gaaaacgggc cagaaggatt agtgacaggt
     5701 aaaaaagcac tgcacatcca atctaatggc ggtgtataca acggacaaga ctttgcctct
     5761 caatatgtaa aaggtatttt aaactttgta ggcatcgatc aagtagatca gctattcatc
     5821 gaaggaatcg attatgaccc tgaccgtgca gatgagttga tgcaaaatgc attagataaa
     5881 gctgctgctt taggtaaatc attttaaaaa ttgagataaa tgcatacaaa agagacagag
     5941 gaaaaaatct tcaaagcagc atttgtgcct tggatatttt cccatctgtc tctttttgtt
     6001 attctttctg ctttttcaac ggattttctt cataaagaga agagattgtt gtgtaccatt
     6061 caaaaacatg agtaatcact actttagctg ctgcataaac aggaatcccc aagatcacac
     6121 cgatgattcc gaacaatttc ccagaagtca gcagaactaa taaaatcgtt actggatgga
     6181 ttgctaactg attccctagt actaatggag agatcaagcg tccttctatt gtctgctcta
     6241 ctgcaaaaac gatcagtact ttgatgatca tgaatggacc tgctacaatg gctaaaaaga
     6301 tagccggaat catcgctaaa aatgatccta agtaagggat caggtttaaa aaacccgcaa
     6361 taatccccaa cgtgacagca tactctaaac caatgaccgc aaaaccaatc ataaacatga
     6421 ttgccacagc aaaagccaca gttagttgtc ctcttatata agaagaaact tgactattca
     6481 tttcactcag cacattcaac gtcggttttt gcatgcgtgt cggtaaaaat ttgacaaaat
     6541 aaggtgctaa ttgtttaccg tctttcaata gataaaataa gataaacggc atcgtcagca
     6601 gagccactaa aatagtcgct accgcgccga caaaacttcc aagactctga actgtactct
     6661 tagatatatc ttggatcata tcgcctgccg aattcatgaa cttatcacct gctgtttcca
     6721 actgttcgcg aaattggttg aacagcgggt cccgcaaaat ctcggttaat ttattatcaa
     6781 tcgtatctac atattgaggg aagttactga tgaagctcac tgtttgttcc tgaatcttag
     6841 ggatgatcac tacgctcccc catgcgatta gtgcaacaac caaaacaaac agcccaatga
     6901 tactgtaaag ccttggtact tttcgctttt caaagtaatc aactaccgga ttcatcaagt
     6961 aatacaagat tcctgctaaa atgataggca gacctacgat tgctaaaaat tgccagattg
     7021 gtgcaaacaa atatgaaact tttgtaaata aaaagacgat cagcaatatt aacaatacaa
     7081 caagtaaggc tgtgactact tgattattta aaaaccagcg ccaaaaccac gataccggtc
     7141 tgttcttctt attttttcct tccataattc ctcctgttag ttataaaaaa tttggcttcc
     7201 caaaccaata gcaggcagtc tatgcggatg aagatagatt ccatttgcaa tttgtccttc
     7261 ttctggacaa gcatcaaaaa tcaatgatac gtgagctact gtctttaaat tcccattggc
     7321 catcggaccg acataatcga tcgtatatac ctgatcatca aaagcaattg ttccgcctgc
     7381 tttcaaagaa aaaggttcgt cttttgatac ttcttgaatc accgaatatt ttcgtaaggc
     7441 agctgttgct gttttatcga acaaaatcag catgggttct tccttgttta ttgcttctgt
     7501 cccaatttct gtaatctttg cctgaatcat tgcactctct cctttaattg ctttcaaaaa
     7561 cagtataaca cattctcatt ctttagccgt gtggaataat tatgtgatag aataaaaacg
     7621 aaaactattt cattacaatt aggaggaatc agctcatatg atcgaaaaga taattttagg
     7681 aacctatacg cgtcgcgaaa gtaaaggaat ctatacgatc gaccttgata cagaaaaaga
     7741 agaattagcc aacctttcat tagctgttga agaaaatagc cctacctatg tagcaaaaag
     7801 taaagctggc aatctttaca cagttactag tgtggatgga ttaggtggtg ccggtgcgta
     7861 cgataaggat tttcattttt tgaatgcggt aacagagtct ggcgctcctt tgtgttatgt
     7921 agcggttgat gaagcacgtc aattactata cggggcgaac tatcataaag gtgaagtaaa
     7981 tgtctaccat atattaggag atggcgaact gaaagcagca gattcaatat tccatcaaga
     8041 agcgacaggt cctcataaaa accaagatca tgcgcatgtc cactatacgg atctgactcc
     8101 tgaccaacga ttagtcgtat gtgatcttgg tacagatcgt gtgtatactt atgatgtgtc
     8161 cgaaaacggc aaattgaatc ttgtaactac cttcactgca gagccaggaa caggccctcg
     8221 ccatcttgtc tttcatccaa atggacaatt cgcttattta tttggtgaat tagacagcac
     8281 agtccgcgtg ctttcttata ataaagaaac aggtgctttt gaagaattac agaaaatatc
     8341 gaccttgcca gaagaattcg acggtgaaaa tggaggggca gctatccgca tttcaaatga
     8401 tggcaagttc ctttatgctt ctaaccgagg acataactcg attgctgtat tcgcagtttt
     8461 tgaagatggt tcccacattc aaaacaagca aatcatctca acagaagggg attttccccg
     8521 cgatttcgca ctagatccaa gcaataattt tgtcgtgtgt gccaatcaga acaccgataa
     8581 tctgacatta tatcgccgtc atcctgaaac aggattactg gaattactga aaaaagatgt
     8641 ctatgtacca gaatgtgtct gtgtttattt tgatcgttag taagaaaagg agaatgaaat
     8701 gaatcagcaa gacgtattag acagactacg ggaagaacta aatattcctt tctttgatgg
     8761 gaaaatcgaa gataaagagt atagcgaaga ggaatatcag aaactcaaag ccgatttaca
     8821 gaactacttt gaacaatatg tacagaatgt agaaaactaa tcagctttcc atactatctg
     8881 aaaagaacat caggacaaga cttttccgtc tatcctgatg ttcttttcta caaataaaaa
     8941 accgccgaga tggttagact cgacggaaaa ggagtattta ctcgattttg agtaagtaca
     9001 aggttgttgt tggttatagg tatgtcatta tcataaagga ttttgatcac tctatcataa
     9061 aggtaatatt acatttatat tagataactc tagtttttat tgttatcaaa gatttctttt
     9121 attttttcaa caacaaatta gtcatttttt ggatggcagc tgtcaattgg tctgtcgctt
     9181 ggtcttgttt tgcttcagat gtattgaata gatcttcatc tacccctgat tcaagatcga
     9241 tactttggat catttcttca cagcctgcta catatgaaag ataagctttt tcaaaatttt
     9301 tatgaatgcc cattgctttt gctggtggac gcaaagtact gactttcata agcattgccc
     9361 gatatttttt tgttccttct tcaaataaca ggatgatctc ttcaagagtc gatttgtcca
     9421 gttcacttgt ttttccttca tcaattgcgt ttctgatcac ttcatatttc ggatgcattc
     9481 cttctccgat tgcttctgtt tccttgacga tttgatcgat ggactgcaca taatagccaa
     9541 tattcggtaa catgttcgtt ttcctacttt ctccattgtt gttattattt attctacttg
     9601 tttttatcct caaatgacaa gtacttgaaa aaatttaatg gtttctatac agctcgccat
     9661 tcttattcgt gctcaaagaa accatctgct aaactatatt gtttccctgc gacaatgtca
     9721 tattggatca attgatattc gtcgtaaatc tcttgttgcg agcgattgaa ttgcgcttct
     9781 ttataccact gtccgttttg atagtacagt tctcgttcaa acgccggaag ttcctgttct
     9841 aatgataaaa gcagctgata aaagccattt gttgtctgat tcgtctgttc cattagattc
     9901 gctgcaaaat aaaacggact ggtgattgca tcgtgagtcg tttgcttttc taattctcct
     9961 ttactgtcga acataagaaa ttgtgtttca tgcaatgttt gtttgtcatt ttttgcttgg
    10021 atcgtatctg aatagatccc tggaagatga tccccccaaa aaacaactaa agtccttcta
    10081 gaaagattct tcaattcttc cgtgaactgc ttcagtgccg tgctgctata ggaaatatct
    10141 tgcagataat tctctaagtc aagtgtccca cttccatctg aagtttttgc aggatagtct
    10201 agattatcat actttccatc gtagggcata tgtgtctgca tcgtgactaa atgaatgaac
    10261 tgaggtgttt tttcttcctt gagaagtgtc attacttctt tgtaagctga ctcatcagaa
    10321 atatatggat tattctctat cgtatccgta taggtcatcg tacgctcgct gatgaactgg
    10381 tcaaatccta atgtctgata aacatcctct cttttataca tcgaagtatt gtatggatgg
    10441 atcgctgtcg tctggtatga ttgtgcgttt aacgctgaaa cgatagaagg aagctgatcc
    10501 atttttggta caagcatcgt gtaaggggtg gtgagttgcg cattaaataa cgccatagaa
    10561 aaaccagtca atgcttcaaa ttcgatattt gctgttccac cgccatagtt ttgagaaagc
    10621 atattgccac tatatgtttg atcagctact tcataataat ctgccaatgg ctcaccagat
    10681 acttctacgc cgtttaatcg actaggatct gagaaacttt cactcatcac gaacacgatg
    10741 ttcggcgact cttcctctac agttttattt ttttcatcgg ctagcttctg gtatttttca
    10801 gtgatttctt tgatcttttc tttcgaatat ccttcaggtt catccattgg ttctaccttc
    10861 agattgtaca aaaacccacc gataaaacca gtgttatagt agttcatttt ctggctgtaa
    10921 ggtatccata gtgccgtttt attatatgct tttcgcaaca aattatcggg attgttgaaa
    10981 ttactgatat accctagcag tccaattgcc acaagcagtg tcgttaatcg gatcaattgg
    11041 aatcgccttc cttttttcag gcttcgaaac atgtaccagc aaaacaatcc tatcacggtt
    11101 cctgcggcag ctaagatcac tgtaaacagc atagtgccgg tcatatcttt cagcaatccg
    11161 atttcagtga tcatcttcaa atcgtctgga taaatcggtt cttgccgata actcattttc
    11221 atataatttg caaaacctaa tacaccgatg gctacgacat acgtaaggga acctaaaggg
    11281 acagatcctg ctagtgcaat cagaaaaata agaataatca gcaagacgag acaggctaag
    11341 aagaattttt ccgtatgcca agaaaaagca aatttcaacg caaggtctac ggatagatca
    11401 ttttgacacc actgcaaaaa taaattacta aaaacaacaa gaaaaaagat actgatgatt
    11461 gctgctgttc cttttaaaat ctttttctgt ttggtcgaaa gtctgcttat atatcttttc
    11521 aaatgcttgc tccttcattt ctatcaataa aagaatgttg cttctcttat tttagttgta
    11581 cgaaattcga aagtaaagaa cggaaagaag aattaatgaa atccaaatat tctctttctt
    11641 tatggccttt ctggtttctt taataagcgg acctttcgta ctccagaaat tttttctagc
    11701 tgttgtttca cttgattgag ctgttcaaaa tcagtactgt ctatgtcaat caatatgtag
    11761 acatgctcat tcttatggtt acgcgatata tctgcgatcg ctagctcgtt ctcattcagc
    11821 agagaaaata tctctgctaa tatattggtt ttcttttgat aaaatatagt gaatcgaaac
    11881 ggcgcttgga aaaacattcg tgcggatgga taattgaccg cttctctaac cgtaccgaac
    11941 aaaagataat cttttaaggc ttcaactgcc aaacgtccgc tgtctgccaa agcttcctga
    12001 gtcgatcccc ctagatgagg caacataagt atacggtcat tttctaagaa ctcttcttct
    12061 ggaaaatcag tcaagtattt agccagatgt tgtttttcca atgcttgcat aacagcatat
    12121 ttatcaacaa tttcacttct tcctacattg ataagtacag catctttttt cattttttct
    12181 atattcgcct gatcgatcaa tccttttgta tcttctgtca acggcagcat gactacgatg
    12241 taatccgagg tagaaagaac tgtttctaaa tctgcttgcc gaacataatc caactgggca
    12301 tcgcggatag aataacccaa gacatccatc cctaagctat agcaacttag cgctactttt
    12361 gtgcctatcg ctccaagacc aagaagaccg atggttttgc cttgcaattc tcgtcccaca
    12421 taagcacttc ttttgttttc tgcctgttct aaaatattag gacctgttag tgtttgtacc
    12481 atacgacttg cttcgattat cggacgggaa gataagagca aacagcacaa aacaagctct
    12541 tttactgcat tagcatttac acctggtgta ttcatgacga tcgtcccgtt ttcagaagct
    12601 ttttcaacgt tgatcgtgtt caccccaaca ccagctcttg aaattgctag caaatctggt
    12661 gtaagccatt catctttcac tttcgtacta cgaataacta ttccttcggc tggcaaatca
    12721 tctattattt tgaaatattc cccttgtaac ttttctatct cttgttctgg aatagcatca
    12781 atcaaatgaa cgtgatacat aaaaccccct ccttactaac aagtatctcg aaatttctgc
    12841 aattagacaa ctgtttacca tttgacttcc tagaagcaaa aagagcagtt agagcagagt
    12901 aggctgagtg ataaaaataa ggctatgaca agttactgcc ataagcctta ttttcgagag
    12961 caaaatattg agggtgagat atcttgataa atggtgttcc gttagctgac attgataata
    13021 agactaaatt tcaaaaaagt tgaaaagcaa atttcgtcaa tctcttctta tttcttaaaa
    13081 ctaagtggct ttttcacaac ctctttttat ctaataacca ctgtttccaa ctcaactaat
    13141 tttgcccacg tttcaatttg atctgttgtt agatttagcg agacaacggt atgatgaccg
    13201 ccacctgcct gaatccatga atggacacct tcatggaaat tcggtttagt tttccataac
    13261 acacgtgcaa caggtaaatt aggtgcttca gtcgttggtt caaaggcttc tacttcattg
    13321 atcagcagtt tataatgcgt accgaaatct gccatcgata cgactacccc ttctcctgct
    13381 ttcccatcaa atacaagacg cgccggatct tctctatctc ccattgataa aggagaaaca
    13441 acgattcttg gtttcgtcgc agcaagcgtc ggatctactt ccatcatatg ggattccaag
    13501 attgcttctt ggccactagc tagctcgtaa gtataatctt ccatgaatcc tgtatctttc
    13561 cctcgagcca tgattttcag caaccgatca atcgctgcag ttttccagtc gccttcccca
    13621 gcaaaaccgt atccttctgc catcaaacgt tgtacagcta gtccaggtag ttgtttcatt
    13681 ccatacaggt cttcaaaatt agtcgtaaaa gcgttatagc ctccttcttc taagaaacgg
    13741 cgaataccga tttcctgctg agcttgtact tttacatgtt cctcccatgt cttttcttca
    13801 taatcaccat agtcgaaggt atacaattcc ttgtactctt caaataattg atcgacttct
    13861 tcgtctgata cgcgatcgat tacttgtaca agatctccga taccaaaata atcaacagtc
    13921 caaccaaatt gaatctgtgc ttccactttg tctccttctg tgacacccac gtttctcatg
    13981 ttgtcaccaa aacgagccac ttttattcca aaactttcat tataggctac tgcaacatcc
    14041 atccaatcag caatctcttt ttggatctca ggtcgtttcc agtagccaac gacgatttta
    14101 ttttgtttat ttaatcgagc attgatgaac ccatattcgc ggtcaccatg agcggattga
    14161 tttaaattca tgaaatccat atcgatcgtt ttccaaggaa tgctttcgtt atattgcgta
    14221 gctaaatgaa gcaatggttt ttgtagaagc tttgtcccgc ggatccacat ttttgctggt
    14281 gagaaagtat gcatccaagt gatcacacct gctacttctt ctcgataatt gacctctttc
    14341 atgatttttg tgatcgtatc agcagtaact gctaattctt gaaggcggat tggataaggc
    14401 aattggccat tttcattcag ttcatcgacc atttcttgtg catgtttctt tacttctcgc
    14461 agtgcttctt ccccatataa atgctgtgat cctacaacaa accaaaattc tttttctcca
    14521 atattcaaca taattagcca ctccttttat ttgttttgtc cgtaatacgc attttttccg
    14581 tgttttcgta aataatgttt atctaaaatc cgttgaggca gctcttctga aaatgaattg
    14641 agctgtctgg taaataaatt catcttgcat acttcatcta gtacgactgc gttcattacc
    14701 gcactttgcg catctttccc ccaagtaaat ggaccgtgtc cgtgtaaaag tacccctgga
    14761 attgctaagg gatcaatttt gcgttctttg aatgtttcta tgataacttt tcctgtttca
    14821 tattcgtacc cgctgtcgat ttcctgttgt gtcaaaaatc gagcacaagg taccgatcca
    14881 taaaaagtat ctgcatgcgt cgtccccatc gcaggaacat ccaatcctgc ttgtgcccag
    14941 atcgtcgccc atgtcgagtg agtatggacg attcctccga tttgaggaaa tgaacgatat
    15001 aaaacagcat gagtaggcgt atccgaagag ggattgagtt taccttcaat gatatgattg
    15061 tccaagtcca caacgaccat gtcgtctgct gtcatctctt cataactgac tccgctaggt
    15121 ttgataacga aatatcgtgt ttcaggatca aaagcgctca catttcccca tgtatatttg
    15181 acgagtccgt gtttaggcaa gtcaagattt gcttggtata cttcttcttt cagttgttcc
    15241 agcattttct atcactcctt tttcttgcaa ttgatgaatc gctgtttttt caatgtcgat
    15301 cccctcacgg taacgtctca taaatatctg atagcctgct atttcttctg ctgaaggtgt
    15361 gatggtgatt ccttggtctt gtccaaacac gtcttctgcc aagaagtttt ctaaagactt
    15421 cccatgtcga tccatcatat aggctgctaa taacgcgatt ccccacgctc caccttctcc
    15481 ggctgtgtcc atcactgtaa ctggtgcctc catagcagat gctagaatcc gctgtccaac
    15541 ttctggtgtt ttaaaaatcc ccccatgccc cactaaacga tcaatttgga cattctcaga
    15601 tttcaatata tccattccga ttctcattgc accaaaagca ctggctaaat ggatccgcat
    15661 gaaattcgct aaatcaaaac ggctacctgg tgtacgtaca aataatggcc ttccttcatt
    15721 tactcctgta atgttttcac cggaaaaata accataagaa agtaatcccc cgcaatccgt
    15781 atcgccttct agcgctttgt tgaataatac cgtgaataat ttatctctgc ttatctccat
    15841 acccaaagaa ttggtaaatt cttcaaaaat actgacccaa gcattgatat ccgaagagca
    15901 gttattcgta tgaaccatgc ctactagttc tcctgaaggt gtagtgacca tgtcgatttc
    15961 cggatggaca ttttctagtt ctttttctaa tacgatcata gcgaaggcgg aagtaccagc
    16021 cgaaatgttc cctgtccctt tggctacact gttcgtagcg accataccgg ttcctgcatc
    16081 cccttctggc ggacaaaccg ggattcctgg tctcaaattt cccgtagggt cgatcagata
    16141 agcccctgat tcgcttaact tgccagcttc ttctcctgct actagaactt taggcaaaat
    16201 gtgatccaag tcaatcgcta cgtgcgcttt ttcgattaac tgaccaaaaa tatttttcat
    16261 ttcttgatgg taggttttcg ttgaaggatc gataggaaac atgcctgatg catctcctac
    16321 gcctagtact ttctcaccag taagctgcca atggacataa cctgcaagcg ttgtcaaaaa
    16381 attaatttct ttcacatgtt cttctttatt caaaatagat tgatacaaat gagcgatact
    16441 ccatctctgc ggaatattgt attgaaattt ttccgttaat attcgttctg cttcttcagt
    16501 gattgtattt cgccaagtac gaaatggtac tagtaactgt tccttgctat caaatgctag
    16561 ataaccgtgc atcattgcac tgaacccaat cgacccgatt gtcgtaagat tctcgccata
    16621 gatttcgaat acttctgctg ccatttttcg gtaactgacg cgcagtcctt tccaaatatc
    16681 ttctaatgaa taggtccaga taccattttc tagtttgttt tcccactcat aactaccagc
    16741 ggcaatagga gtaaaagatg aatcaatcaa tacagctttg atcctagttg atccaaactc
    16801 aatccctaaa gatgtacgac catctatgac atctaacata ctttgcgcat ttacttcctt
    16861 cataatgatt taactccctc cttctcgtca aacctgatca aaccgtcttt ttagtagcgc
    16921 ttacaatgat tattgtatac ttttgtacgt acatgtcaag cagttattta caagaataca
    16981 ataaaaaaca cttgttttgt acgtacataa gttataaaat gaaattgctt acaaaatctg
    17041 atcaaccgcc ttctcgaaat tctagaagga gagaatactt atgaaaaaag aaaaaaaagt
    17101 ttcctcatcg tttatttatt tttttggcgc atttggcggc attctatttg gatatgatat
    17161 tggtgttatg accggcgcct tacctttttt acagcatgat tggggtttgg caggtaaagc
    17221 ttctttgata ggatggatca cgtcttcggt catgttaggt gcgatccttg gcggctcttt
    17281 atctggtctt ctttctgata agcttggacg acgaaaaatg attcttcttt ctgcacttat
    17341 ttttatggct ggttctgtcc tttctgcatc tgcccctcac aatggttctt attttctgat
    17401 tgcagcaagg attcttctag gtttagctgt tggcgctgca tctgccctag ttcctgctta
    17461 tatgtctgaa atggctcctg ctagactaag gggaagattg tcagggatca atcaagtgat
    17521 gattgcttct ggcatgctcc tttcctatgt tgcagattat ttgctaaaag ggttgcctga
    17581 aacgatggct tggcgcgtga tgttagggct cgctgctgtc cccgcgctga ttttattttt
    17641 cggtgtttta gctctaccag agtcaccgcg ttttcttatg caatctggcc gcttggaaga
    17701 ggcaaaaaga gtattgaact atattcggac accaaaagaa gctgaacagg aattcgaaca
    17761 aatccagctg aatgtcaaac aagaaaagac aaccggaact tcttggcata ctttgttttt
    17821 agaaaaatat cgttccttag tcattgccgg tattggtgta gcagtattcc agcaatttca
    17881 aggagctaat gctatttttt actatattcc gctgatcgta gaaaaagcga ctgggcatgc
    17941 agcgagcgat gcattgatgt ggccgatcat ccaaggaatc attttagttg ctggttcttt
    18001 gctctttttg gttattgcag acaagttcaa tcggcgaact ttattgaaaa taggcggtag
    18061 cgtgatggga ctttctttca tcctaccagc tgttttagga actgtactgg atgctcatac
    18121 aaattcgttg ttgattctct tgtttttatg tatttatgtc gcattttatt cttgcacatg
    18181 ggctccactg acatgggtaa tcgtaggcga aatattccca ctagctgtcc gcgggcgagc
    18241 atctggccta gcctcttctt ttaattggat tggttctttc ctagttggct tgctttttcc
    18301 tgtgatgact gcttctatgt ctcaagaaat cgttttcggc atttttggga tcatctgctt
    18361 tttaggggtt ttatttattc aagagatcgt accagaaact cgtgggaaat ctttagagga
    18421 aatcgaacaa agtgcatcta aaaaaactta tcctaaacgt atttctatcc atcattctta
    18481 aagaggttgt gacagaagtg gtcagcttca agaaataaga aggaaccgct tagtttccag
    18541 tcacaaggaa caatttcaaa aaacagcttc tcatgtttga tgaatattgt gacttgtgac
    18601 cagttggtag gagaacaccg tttagtggag aggtggtgaa agaaacgttc agccttgagc
    18661 gatgacaaaa gctctcacaa acattgcgac gagtaaccgt aggagcaata agaggcggta
    18721 aaaacccgtc tcttattttt cgttttcttt cactgtttcc cgttcaacta gtacaggttc
    18781 atagagaata tttggctgtg cctgtccttt ttcaatcgtt gtgacgatcc accgtgcggc
    18841 atcttgtccc aacttttctt ttggatgcgt caatgttgtc aattttttat tccctaaatg
    18901 gcttaaagaa gaatcgtctg ttcctacgat cgataggtca tctggaatat gatagccatt
    18961 ttctgtcaac ttatctagca ttaaactagc tatttgatcg ttatagcaaa tgatgccatc
    19021 taaagcttgt tcttctttca accgttgtac tgttttttca gcgattgttt ctcgtgtttc
    19081 cgtggtgaaa gtaatgatat cttccgtcaa aaaacgcaca ttatactgtt cacacgcgct
    19141 gataaaacct ttcatcctgt attttccttg aagatcgtcg atttttgtga tgaacaacag
    19201 acgctgatgt ccttttttta tcaaatattc tgctgccata aaaccgactt tcacatcatc
    19261 taaacaaata taagaggcat ttaactcttc ataagcagca ttgatcatca ccatcggaat
    19321 gccttgttct ctcaaagcaa cataaagtgc taagtttggg ttatactgat tacttttcgt
    19381 aggctcaacg atcaaaccat ctaccccata agcaatcatt ttcttcaaac actctttctc
    19441 caattcgtga tcgttattcg tactggctaa aagcaatgaa tacccagatt ctcgtaattc
    19501 attttcgatt cctcggataa tcgacggaaa aatataatca gagagatatg tggtgatgac
    19561 accgatcgtt tttgttctgt tcaatggtgt tttttctttc ttatagctgt catctacata
    19621 tgtgcccgac cctttttctt tacgcagata gccctcattt accaacacag cgattgcttg
    19681 ccgaatcgta tgtctgctga cgtcatatat ttcttgcagc ttgaattctg agggaatggt
    19741 tgtatttact tcgtattcct cacgaaggat cttttgtttt atctcttctg caatatcttg
    19801 atattttgcc atttgccttg ccccttttta tttgtacgta catatatcat aacgagtctg
    19861 caaggtttat tcaagcaaaa atcaaggttt cttgtgctca taaggcatac ggaacaggtt
    19921 caccaaattc tggaaatcct tgctcattcc acgtaaagca ttgcgcgttc gcgtgccgat
    19981 taggattgtc taacggatcc cctttttggt tcttctctgg tcgagcatga tagatcaaaa
    20041 tatcaaagca cccgtcttct gaaaccgtaa acgagttgtg accaggacca aattgcttat
    20101 ttttttcaga agaaacgaat actggctccg ataatttatg ccatgattct tttaataaaa
    20161 gattcttgtg ctcatcagcc cacagcaggc ccatggcata gttttcatct gttgcactac
    20221 cagaatacgt aatgaatatt ttcccattgc gagtaaggac tgctggacct tcatttactg
    20281 aaaaaccccg tttttcccat tcatactcag gtatagaaag gaggatctgc ttccccttta
    20341 acgtccaagg attatccatt tcggatagat aaagattaga attcccagta atttcaggat
    20401 cttgttgggc ccacacataa tatagctttc cttgagaaga gaaagttgtt ccgtctaaac
    20461 tgaaagtttc ccttttcgtt tttatttgtc ccttttctat ccaatctgta ttcattggat
    20521 ctatatgctg attttcaagt acgaacatgc ggtgatgatg agattcatca cgtatagttt
    20581 tatgattgct tgcagcaaag taaatatacc attttccatt gatataatgg acttcaggtg
    20641 cccagatcaa ttcactcatc ggtccttctt catgagcctg ccatacaatc aggcttgcag
    20701 catgttctaa ttcattcagt gactttgccc ttcttaattc aatcacttgg tagcctggaa
    20761 ccgatcctgt aaaataataa taaccatctg tatgtttata tacccaagga tctgcccgtt
    20821 gccgaacgat aggattatta taaagtgtct tcatcataac aaatttcctc acattttctt
    20881 tattctaatt acattccaag agtatttttc tatccctaca tttaattcgt catgtttttc
    20941 tattgaaaaa tagtttattt caggttttat tttttctggt tcttcacgtg tatttttgtc
    21001 caacagatcg ctactggtta atgtgtagtg ctctccttga tctagcaaat tgaaatcatg
    21061 ttcaatcgtt atcttttgtt gttcatttgt gcgattgatc aagaaaatag tcagctgatt
    21121 gccgttatct acgatcacac tgtccacata aggaacattt tttatctttt cacaatcata
    21181 aacagggcaa atgatttgtt gtttcaatac ttgaccttta gcatatttcg ataagtgttg
    21241 catcacataa taagttggat tcctccatgc ttgtccttta gcatctgtca gtattaaagg
    21301 tattgtgttt actaacaatg attgacaact aatctttacg cgatctgcgt gtcgtaaaat
    21361 agccagccct aatgaaccaa ataataatgt atcttccata gtaaagtaac accaatcgat
    21421 gggactaccg acttcaaaat ccctatgtct tttttccggt tgggcatgta cattccattc
    21481 atcaaacgct agatacattg ttttctcact tctcaaatat ccttttacat aatcacaagt
    21541 agcaacgatt tcttcaattt gacgatcgaa tcgataagct tttgcaaggt atgtcgctgt
    21601 atcatcacgc tcatttttag gaggtttagt caagtcttct tcatcatact tatcaatata
    21661 gttatgcaaa gctaaataat ctacattctc ataagcttct tctaatgcga tacgatccca
    21721 ttcagggtac gatggtaaac gtggcgtaga gcttccaact aagattgttt caattgaatc
    21781 atccactaac ttcatgactt ttgaggcttc atttgctaac ctaccatatt cataagcact
    21841 cttagccccc acttgccatg gaccgtctag ctcattccct aaacaccata atttaacgcc
    21901 aaaaggcttt ttttgcccat tttttattct taaatcactc cagaaggttc cttttggaaa
    21961 attacaatat tctactaaat tttttgcttc atcaattcct tttgttccta aattcaccgt
    22021 gaatatcggt ttcgcttgta catgactgat ccatttaaaa aattcgtgga gtccaaaaga
    22081 atttggttct atacctcgcc atgctaaatc aatttttttt ggtcgttgtt ctttcctacc
    22141 tacagtatcc acccaatcat aaccagatgt aaagtttcct ccaggatagc gaatgacacc
    22201 taattctaat tcctttacat aagagaggac atcttgtcta aacccgtcac catcagctgt
    22261 ttcatggccc ggttcataaa tccctgtata gacgacactt cccatatgct caacaaatga
    22321 gccaaacagc cgagaactga tctctcctac cgtaaaatcc tctctgattt ttactttcac
    22381 ttcttcgtcc aacagctttc cctacctttc atttcctata gtcaagataa tagatacaag
    22441 tttccatacg ccaccagcaa agataaaaat aaaaggaggg aaaagaaata tgagcagtac
    22501 aaatcctaat aacaatacgc aacaaagaat atttctcaaa aaatcaaaaa atactttcca
    22561 tgcactttgt tcaaaaattt gtaaaaatgt gatatctttg ttttcagaaa tcacatatat
    22621 ccaggataaa agaaacatgg aataaataag taaaactaca tatccactaa ttgaaagtac
    22681 gattgtctgt tcttctaata attgattaac aagaaaataa ataatgatcg ttaacagact
    22741 aaggaacaag ttcttaccaa aatgttgctt tattccttga aagaaaaaat aaatgatatt
    22801 tcctgatccc tcacctttcc attgcgccat tacataaaaa aacagcacat gtagcaggca
    22861 cgatagtaat aacaggcaaa cacacgatta cccagagaat acctaataag atgtaatcag
    22921 aaaccacaat caactgtcca taaagtttag tctcaactat tttcatcttc ctcactcttt
    22981 cattccagac atagctgttc cttgaacaaa atatttctgt gcaaaaatat aaaccactag
    23041 taatggcagc attgaaataa ccgttccagc cattacaggt ccataaaaag aaatgttctg
    23101 ccctgtaaat aaagctaacc ctgctggtaa agttctcatt tttgaactac ttgtcaatat
    23161 caatggataa agcaagtcat tccaactatt catcagcgtg aaaatcccta atgataaaag
    23221 agtaggtttg ctcaatggca acatgatttt caaaaaaata ttaaactcac ttaatccatc
    23281 aatgcgtgct gcctcttcca aagaatctgg taaagtaata aaaaaggaac gcatcatgaa
    23341 gataccaaat gcagttgtca tacgaggaat gatcaaacct gcataagtat caagcatgcc
    23401 aagcaaattg acttcaataa atagaggaat catgaagact tggaatggga tcatcattgt
    23461 cagcaaaacg aaatagaaca aaactgattt tcctttgaaa cgcatacgag caaatgcata
    23521 ccccgcaaga gaatcaaaga atacagaagt gatcactgtc cctccagcaa aaatcactgt
    23581 atttttgatg taatctaata aagggatcgt tgtccaaacc ttaatatagt tatctagggt
    23641 atagctatct gcaaatattc taggcggaaa tgagataatg tctttttcgt gtttaaaaga
    23701 agaaataatc agccacaaaa aaggaaacgc aataaccaac aatataacta gcatactaat
    23761 cgttcgaatg atttttttac cactaactgc ttttcgacta ttcacagtaa ctgtaatcga
    23821 gctttctggt gccatacagg tttccctcct atttcatttg tttttctttc cgtgacatgt
    23881 acacattagt ggagatagct atagttgcaa caatgataaa caaaaccgaa gacagtgctg
    23941 atgcatagcc caattcataa ggtgctgtaa atcctcgact gtaaatatat tgaacagctg
    24001 tttctgtctt aaattgtggg ccaccagcgg ttgcaacata tacttggtca aacacttgca
    24061 tcgaaccaat cagattcgtt aaaatacaaa aacctaagga gggaacgatc tgaggtagcg
    24121 taatgttaaa aaactgctgt cgatttgttg caccatccat ttgagcagat tcatacaaag
    24181 agggagagat tccctgaata gcagtcaaga gaatcgtcat agtaacacca aaattcttcc
    24241 aaacagtcat gatggctacc gtcggcatag caagggttgg atcgcgaaaa aattgaggga
    24301 tcggcaagcc gacttgtgaa aacaagtaag gaatcgcccc tacattcgga tcaagcaaca
    24361 tagaaaaaat aatcgcaatt gacgtcaatg aacaaataac tggaatgtaa aatgtcgaac
    24421 gacaaaaacg attgaatctg gtatttttag ataatgctac tgctgctaat aaaccaacga
    24481 taatttgtgt tggcgtttcg agtacggtga aatataaaga atgaatcaac gaattaactg
    24541 ctcgttcatc actaaatata cgtgtgaaat tttcaaaact tacaaaattt cttgatgtaa
    24601 agaaaatatt caaatctgta aaactaatag caaatgttcc taaaagcggt atgacagtaa
    24661 ataataataa aactaaaaaa gatggagtta aaaacaaata cgcagcacga tcaggacgat
    24721 tccaatattt ggtgaatccg ttcatatagt ccacctcatc tttcattttg ataaaatata
    24781 caatcttggt ttaaacgaat ctgaataaga tatccgaaca atcgctgtga tttttgcaat
    24841 aacacctatc tgcaaatact aggtcgatca ttcagatatc tgtatcttgc caacagtcta
    24901 tcctgtataa agttctgtac tatttttgca gtaattgatt gatggcatca tctgcatcgt
    24961 tcatgagtgt ctcaggatct tctcctgcta ataatttttc aatcagtgga ttgatgatat
    25021 cgttattgat cgcagagatt tgggtaaaac ctggtaaata tggctctgca tagtccattt
    25081 gtttcgataa ttcagataca ataggatcat tttttacttc ttcatctttt gctactgaat
    25141 ccaagtaggc aggaaaacca ttttcgatac tccatttttt accaatttca gttgtattcc
    25201 aatatttcaa aaactcatag acagcttctt ttttattatt atctgtactt gccggaatgg
    25261 catatcctac gccatctaaa atagctgttt ttttgtctga atcactccct tgtggtaagg
    25321 tagtcacatt ataatcaatc tcgtttgctt tcaatccgtt atttaaccat ggcccattga
    25381 tttcaatggc tagttgacca gcattcatta aattgtccat ttcggcgcca gaaatcgatt
    25441 ctggaccagt cttgtctaca tggatcattt tttggatcgc ttttaacgtt ttaaggttct
    25501 caggagacgc aaattcagac ttagtataat catcgttcac taatttaccg ccatttgcta
    25561 acatccagtt atataacggt gcagttccat ccttattgaa gacaaaacct gatacatttt
    25621 tactactatc agttaatttt ggtgccattt ctgtcaattc ttcccaagta gtaggtggtt
    25681 gttcagtatc taatccagct tgtttaaaca aatcattatt ccaatacata tacatgcctt
    25741 gtacctgcat ggggacaaaa tactgtttac cttctacttc acctaattca atagccgttt
    25801 ctttaaaatc agatttatct actccatcat attcccagaa atcgtctaat ggttgtaccg
    25861 ctccgttttc tacatactgt gcaaaatctg gataatttaa tgcaataaag tcaggtgctt
    25921 ttttagaaga aatcgctgta ggaagttttt cattcaaatt ggcccaagtc atgatatcca
    25981 tttcaatttt gatgttttta tcatttgttt tattaaattc attaacgatt tcttgcaata
    26041 tttcaccatc agatgcagta aacccattcc aaaaagtcaa agtcacttct ttatcagaat
    26101 cagattctgc tgaacttccg ccaccgcaag ctcctaaaat acctgttgca gctaccaaca
    26161 aagagccaat taaccatttt ttacctttca ttttttgttc ctccttcatc tgataaacga
    26221 catctgacca cattccaaga tagcggtttc aataaacaat tgattttccc atcttcagct
    26281 tttacatttg ttgaatgact tggttttact tgttcacttt taggaagatt agttgctttt
    26341 gtatcaaatc cactcatttc agaaaaatca atcactccct ctaatgataa ttcagacaag
    26401 tgaacagtta gattcatttc ttcttctcca cggttaactg caaatatgac aagttctttg
    26461 tcatttatta cggctatact ttctaaatac ggcacttctt caaaatcttc cgtcgcatag
    26521 tttgctgaac gaatttgtgg gcttaacacc tctccttgtc catacacagc agcttgcata
    26581 aatggataat agatcgtctg tctccaagct tctccgtttg tttctgtcct gattggtgca
    26641 ataacattta ccaattgagc aagacaagca atctttactc tatctgcatg tttcaataaa
    26701 gtgattaata gacagcctaa tagtaatgca tcttcaaaat tatagttatc ttctagtaaa
    26761 ggaggagcaa tctgccaagg cgctgcttgc tcatcttgtt ccgctgaatg ataccaaata
    26821 ttccattcat caaaggacag gttgatctgc ttcttactat gtttcttcgc cttgactgta
    26881 tcgcacatcg ctgtcacttc agaaatgaac cgatccatgt ctaaggaacg tgcaagataa
    26941 tgagaaagat catttttttg gttgccataa tattgatgca gagacaaata atctatttga
    27001 tcgtacgctt gatcaagaac tgttaactcc caatcaccaa atgtaggcat ttgccgattc
    27061 gaacttccgc ataaaaccac ctcaattgaa tcatctacga gtttcatcgc cttagccgtt
    27121 tcctctgcta accgtccata ttcttccgct gttttatgtc caatctgcca aggaccgtcc
    27181 atttcattcc ctaaacacca tgtcttaatt ccaaaagggc tctcttgacc attcgaacgc
    27241 cttaaatcac tccaataagt tcctttagga aaattacaat attcgactaa attacgagct
    27301 gcatctactc cacgagtacc cagattgaca gccatattga tttcggcccc cacatgctga
    27361 caccagttat aaaattcatg aatcccaact tcattcgttt caattgtccg ccaagctaaa
    27421 tccaaccttc taggtctatt tgctatgggc ccaatactgt cttcccaacg aaatcctgac
    27481 acaaaatttc caccaggata tctaatcatg ggaatgttca attcttttac caagtgaatg
    27541 acgtcttggc gaaatccact tttattagct gatggatgat ctggctgata aatcccttca
    27601 tatactgctc gtcccatatg ttcaataaat gaactgtaca accgcggatc aactttgcct
    27661 acacgcttga cactactaat caacattgtg gcttccataa ctgacctcct ttaatttata
    27721 catgaataat acacctcgtt gaaagcgttg tcaataatat aaatgttaaa cttacttatt
    27781 ttttatcgat tt
//
LOCUS       DACCVZ010000032        27235 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.032, whole genome shotgun sequence.
ACCESSION   DACCVZ010000032 DACCVZ010000000
VERSION     DACCVZ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27235
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.032"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            656..988
                     /locus_tag="IVW63_001399"
     CDS             656..988
                     /locus_tag="IVW63_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAP7859680.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYAGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            1607..1948
                     /locus_tag="IVW63_001400"
     CDS             1607..1948
                     /locus_tag="IVW63_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAP7859681.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYYQKLTDNPIGFGLLPEDDEGNEWFKMTLTNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            2062..2301
                     /locus_tag="IVW63_001401"
     CDS             2062..2301
                     /locus_tag="IVW63_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859682.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            2413..2607
                     /locus_tag="IVW63_001402"
     CDS             2413..2607
                     /locus_tag="IVW63_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859683.1"
                     /translation="MEEKLLKTMKQKHLKRLSVMQYINDMQITGKEKACLLGSMKNFE
                     QLRRTYVKTSSNCQLLLEVS"
     gene            2693..3364
                     /locus_tag="IVW63_001403"
     CDS             2693..3364
                     /locus_tag="IVW63_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAP7859684.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQQEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            3417..5393
                     /locus_tag="IVW63_001404"
     CDS             3417..5393
                     /locus_tag="IVW63_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP7859685.1"
                     /translation="MAINRYVKKAGMLIGMLGIIAGCFQGYRAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            5408..6160
                     /locus_tag="IVW63_001405"
     CDS             5408..6160
                     /locus_tag="IVW63_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP7859686.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTILSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLESNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            6176..6931
                     /locus_tag="IVW63_001406"
     CDS             6176..6931
                     /locus_tag="IVW63_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859687.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGHEKQEGVNG
                     AKFSVYDVSDILQKMDVKDLTTDQIESQLKNRVKKLSSDQLKLVSNEETKTIDQQTGV
                     FEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSEAS
                     QPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            6944..7204
                     /locus_tag="IVW63_001407"
     CDS             6944..7204
                     /locus_tag="IVW63_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859688.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            7201..9291
                     /locus_tag="IVW63_001408"
     CDS             7201..9291
                     /locus_tag="IVW63_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP7859689.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            9318..9782
                     /locus_tag="IVW63_001409"
     CDS             9318..9782
                     /locus_tag="IVW63_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859690.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            9779..10021
                     /locus_tag="IVW63_001410"
     CDS             9779..10021
                     /locus_tag="IVW63_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859691.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            10039..10341
                     /locus_tag="IVW63_001411"
     CDS             10039..10341
                     /locus_tag="IVW63_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859692.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            10411..12474
                     /locus_tag="IVW63_001412"
     CDS             10411..12474
                     /locus_tag="IVW63_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859693.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVA
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKYEKIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEE
                     AQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            12474..15086
                     /locus_tag="IVW63_001413"
     CDS             12474..15086
                     /locus_tag="IVW63_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAP7859694.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFCEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNKEISEMI
                     GKRLLLESEKVVKE"
     gene            15083..17614
                     /locus_tag="IVW63_001414"
     CDS             15083..17614
                     /locus_tag="IVW63_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859695.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKEND
                     QSFVHQSTAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            17664..17996
                     /locus_tag="IVW63_001415"
     CDS             17664..17996
                     /locus_tag="IVW63_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859696.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            17997..18590
                     /locus_tag="IVW63_001416"
     CDS             17997..18590
                     /locus_tag="IVW63_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859697.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            18753..20777
                     /locus_tag="IVW63_001417"
     CDS             18753..20777
                     /locus_tag="IVW63_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP7859698.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            20777..21976
                     /locus_tag="IVW63_001418"
     CDS             20777..21976
                     /locus_tag="IVW63_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAP7859699.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            21992..22636
                     /locus_tag="IVW63_001419"
     CDS             21992..22636
                     /locus_tag="IVW63_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859700.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            22647..23453
                     /locus_tag="IVW63_001420"
     CDS             22647..23453
                     /locus_tag="IVW63_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859701.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            23475..23705
                     /locus_tag="IVW63_001421"
     CDS             23475..23705
                     /locus_tag="IVW63_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859702.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            24219..24527
                     /locus_tag="IVW63_001422"
     CDS             24219..24527
                     /locus_tag="IVW63_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859703.1"
                     /translation="MEVRIRNVDEKIVREIDRRCDELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQDKFDQLLNQLIDKFSFVQSHNTKVLEEYICQNNQIIELLIEQSRGGEV
                     "
     gene            24529..24951
                     /locus_tag="IVW63_001423"
     CDS             24529..24951
                     /locus_tag="IVW63_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859704.1"
                     /translation="MAKVIDKHIYFYETHIDVLDEIIATHAEVKNYSEAVRFLCMNYD
                     SEVEKKVNSNQAKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            24971..26560
                     /locus_tag="IVW63_001424"
     CDS             24971..26560
                     /locus_tag="IVW63_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859705.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPEE
                     EQELRLIKNALEDFYIPEGETFSESKTGKEFSETSNEAQSLMKHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKVLTHSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQTFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKKNTRKPYTEIENGVSYIVPKG
                     KRRQATLDEMKTNYVHELERFSYEKNRMGMEKRNLLTRKSDLRNTLTKVVKEPVRYDR
                     HAMSLLTEVYKNLPKKRSEWHYGDENRTKLSPYTREKLDELTQYVLTKEPGYQEYIQI
                     SKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIERMDQ
                     MQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEK
                     YHASKAYEEQQRRIQMEQERQ"
     gene            26572..26907
                     /locus_tag="IVW63_001425"
     CDS             26572..26907
                     /locus_tag="IVW63_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859706.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLINEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            27048..>27235
                     /locus_tag="IVW63_001426"
     CDS             27048..>27235
                     /locus_tag="IVW63_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859707.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT        10117 a         4189 c         5597 g         7332 t
ORIGIN      
        1 caacacaaaa aagagaacaa acgtttgcat gttgctgttt tttagttata ataatacgcg
       61 aagagaggta atttcatttt ttaaaaaagc taaaaacctt gatattactt cttttcaggc
      121 aatacgaata ttattcgctt acattttttt gtataaattt agttgtttta aatttaattg
      181 tctgctacgc ttgtgatgaa ttaattttcg ttctgcactt ttggacgata aatttggaca
      241 attgaaaata caaaaaaaag aaaggccctg tgagactcgg aaggctggta accttcgtcg
      301 acgtccacag gtggcattaa gacaaccttt aatcccttaa tgcgtttacc tttcagtgtt
      361 acggtattac ccgcaacgga tttagtataa cagatattca aaagtgatac cacttttttt
      421 ggctgtgtta aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcataatgtt
      481 ataaaaatgt ccgtgtggct ctttgccgta tgacgaacgc tgaaattaga gggaacgcat
      541 gtttggatgc gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga
      601 aaaataacaa gaaaaactta ttaaaaatat ttaaagtaag tgggtggatt attttatgtc
      661 atatacagga attttgagtc tcgaagatat ttgtcactac ggtaaacggt gtaccgctac
      721 agagaaaatc acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa
      781 atatataatc cagaaagaca aagtctcaga ggaaatgatt tattacgctg gtaaacaaaa
      841 gcaaataatt ttaaaagatc ctatcccttt aaaagaacta tatccaacaa tcaaacatgt
      901 ttatgaccaa aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc
      961 aaaagggatg gggcgtttaa tcagctgaat tgatcattct cataacttgt attttatcgt
     1021 ttttcgcttg cttgaaaata ttgtcgagac ttctaaaaga acttagaatt actagaaaaa
     1081 taaggagtag acttgatcta tcaacaattc ctttcggggg gtgacggggt aggtttttac
     1141 gattggtaac gtaaaaaatt ggtcaatcga gtaaatgccc ttgtttggat agtggtgaaa
     1201 tgaatttgtg taaataatat gcacagagta aacaagaggg aatttagaag ttagacaagt
     1261 tagaatagcg cctagattaa tcatgagcag ctactaaggg atctaggctt tgacgcaaac
     1321 tcatggaata aggagtaggt cttctcgtaa tggggaggac gcacaagaaa ttgtgtcgtg
     1381 tgctgcagta catgtagata cttgcgagga cgttggtcat tggatcaatc gagcatttac
     1441 cgatttctac tagggtttct cgtttcggac gccataaacg agtcgatatt ttttatgtat
     1501 ttttaagtaa acgaaaaacg ataaaatatg aacgagtcct gaataaagtg aaaaaattga
     1561 tataaaacat agagaaaatg aaatttacgt aatggaggaa tgacaaatga aaaattatga
     1621 tccgaatata cgattgggca cacatactat taaggtttct ttccaacgtt gggattacaa
     1681 aggatttgtg acgtttagaa gaggcggaaa ttgtaaagga ttagatgttt tagcattaga
     1741 cgaggatgat ttatactatc aaaaattgac tgataatcca attggattcg gcttgctacc
     1801 tgaagatgat gaaggtaatg aatggtttaa aatgacgctt acgaatgata atggagacga
     1861 attatctgtt gaagatactt ggtcatattt gagtgattat attgtcagcg ttgaaatcat
     1921 tgaatttgta gcggataaag aagaataaaa actggaggaa taaattttac agataaaggc
     1981 ttagaagaag tcacgacgaa taataaaaag gtagtattac cttaggcatt gagtaaggaa
     2041 ttcatttagg aggaaaatta gatggcgcga ccagttttag aggcgatgga tatggatact
     2101 ttgacaaaag gaaggtatgt acagctgtta gctcgtggtt attcacctaa agatgtattc
     2161 aaatccctgt ctaaaggaac agatatggaa aaagaaagat tacgaaaaga attcgattat
     2221 tggagaaccc ataatggaat caaggatttg aaaccagcac ggccagtaat taaacgaaag
     2281 aaaaagataa cccaagactg aagtgtagag cgtatgtgat cataggcttt tttatttttg
     2341 caaaaaacaa ggaaggtagg aaaactcatg aattatgaag aaatcgaaaa cagaaaaaaa
     2401 gtgtcgaaat aaatggaaga aaagttgcta aaaacgatga aacaaaaaca ccttaaaaga
     2461 ttatctgtca tgcaatatat caatgatatg cagataacag gaaaagagaa agcttgtttg
     2521 ttaggttcaa tgaaaaactt tgaacagttg agacgaactt atgtgaaaac aagttctaat
     2581 tgtcaactat tgttagaagt ctcatgacat tcattaatag aattcatttt taaaactttt
     2641 tctatggaaa tgagaaaaag attttttgtt ttgtctgaaa gggggtagct ggatgagaaa
     2701 atggttattt ggttttttag gagtcgcttt aatcgtcttt tgcagtgtgt ttggctatgt
     2761 tagctaccaa aaacatgaag gagaggtgtt taagcaaaat atagaaaaaa agatgcccgt
     2821 agatcaaatc aatgcacatg caaagagtta taaggaggat gcaacgaacg tcaataatga
     2881 tatgtctttg gggcaaatgt tgtccataca acaagaagca atcgaaatgg gcgtcaataa
     2941 acaagtattt gcacaaattc agattcctgc acttggttta gcattgccaa tttttaaagg
     3001 ggcaaatcaa tacactttga gtcttggagc ggctacttat ttttatgaag atgctgaaat
     3061 gggcaaagga aactatgtcc tagcaggtca taacatggaa atgccaggtg ttttattttc
     3121 tgatattcaa aagttgtcat taggggaggt gatggactta gttagtaacg atggcgtcta
     3181 tcgttacaag gtaacgcgta aatttatcgt acctgagtac tttaaattaa tcgatggcgt
     3241 tcctgaagag aactctttct tgtctttgcc aaagaaagga gagaaaccct tattaacgtt
     3301 gtttacttgt gtttatacgt cacaaggaaa agaaagatac gtggtacagg gagaactaca
     3361 ataacaaggt tttaatcaac gtgagtcgtt gaaatatgaa atgaggagag taaaaaatgg
     3421 caataaatcg gtatgtaaaa aaagctggaa tgcttattgg aatgttagga atcattgcag
     3481 gctgctttca gggatatcga gcatatgcag aagatgtcac gcaaaaaacg ccaccagaga
     3541 aggtcaatat cacggttcat aaattaatgt acgatcaagg aacgcaattg aatgttgata
     3601 ttgacgggat caaaaacgat ggttatacgc acgatcaata tcctacaggt gtaacgaaat
     3661 acaacaaggc agattatggt gatgttgagt ttacgttagg aaatattacg gatcaagtat
     3721 taccgagaga agattctgat ctaaccaacg cgaaagtgga cgagattgta caagatgtag
     3781 aagacaaggg atctaacagt gagtacgtca agaatgcaac caacaaaatt acttcagctg
     3841 tagatgaaaa tggtgagatc acttttactg atcaaccagc ctatgtcaat tccaaaggga
     3901 atgtatatgt ggtttatgaa agtaaatccg ctgctggatt agtcacacaa aaagcaaaac
     3961 caatggttgt gattgcgcca atgacagata aaacaggatc aggattttta aaaaatattc
     4021 atttgtatcc taagaacatt gtttctaagt tgagttttga attaacgaaa tttggtgacg
     4081 atggcgcaga ccaaagcaaa caaacccttt taaaaggggc aaaatttgag ttatacaagg
     4141 gcgaacctgg aaaaggaaca aaattgggtg atcttgtatc ggatgatcaa ggaaagctga
     4201 ctgcgactga tttgacgtta ggaaaatact attttgtgga agttccttcg gaagttgtag
     4261 tgggatcaga tcaagaacca acagcagatc aatatttatt aggcgcagac gctcgcaacg
     4321 atgcgcacaa taaattaacc tttgaaatta cgaatgatgg cgtgacaagt gacttaaaag
     4381 cttcatacgt aaactataaa gcaccagtga tcgataaaac agtaacaaat ggaacaggac
     4441 aagaacattc tttccaaatt ggtgacgcag taaattatca aggaacgatt catattccaa
     4501 cagacattgc aggtggcgca gacggtatca cagtaaacgg tgtgaaaagt gaaacttctc
     4561 cttacagtgt atttaaatgg ggagatacag caggacaggg actttcttat gtcgctgcta
     4621 aagcaaatat caaagtaaca aataaagatg gatctgtggt attaaaagaa aatacagatt
     4681 ataaaatcca aaattcagaa aatggctttg tgatcgattt tatcgtgaat aatggccaag
     4741 taagtgatac tgtagcaagt ttacacggac aagatcttca aatgacttat aacatgtatg
     4801 taaatgacag cgcagctgtt gccaatccat taacaaatag cgtggatttc gtttataaca
     4861 acaatccatt taatcaggaa gaacaccacg aaaaaacgaa agctgacgtt gtgacttatg
     4921 gtgcaaaatt cttaaaagtc gatagcggac tatttggaac aggaatcaaa gcaacaccgc
     4981 ttgaaggcgc agaatttgct gctaaaaacg cagaaggaaa atattatggt ggattagttg
     5041 atacggataa agacggtgtc aaagaagcag tatgggtaga cgatgtagca aatgcagcga
     5101 tcctaaaatc agataaagaa ggtcactttg aaatcactgg tttaactgaa ggtgaatatt
     5161 cactggaaga aacaaaagcg cctgaaaact atcaaaaatt aacgaaagag atctctttca
     5221 aagtagacaa agattcatac aaagaagaaa accgaatcac gatcaaaaac aatcaaaaag
     5281 cttccgtacc aatgaccggt agcaacggtt ttcaaacgta tgtattaatc tcttgcttgt
     5341 tgctaggagc aggggcactt tctgcagttg tttactttaa gaagaaagcc tagaaggatc
     5401 aaaaccaatg attatcagga agcctaagaa aaagcgaatc atgggtaaat ggatcattgc
     5461 tttctggtta ctttcagctg taggtgtctt acttttgatg cctgctgaag cgagcgtggc
     5521 gaaataccaa caaaatcagc agattgccgc aatcgatcga acaggaacgg cagcagaaac
     5581 ggattcttct ttggatgttg ctaagattga gttaggcgat cctgttggta ttcttacaat
     5641 tctaagtatt tctttaaaac taccaattta tgacggaacg tccgacaaaa ttttagaaaa
     5701 tggtgtaggt attacggaag gaactggtga tattacagga ggaaacggta aaaatccttt
     5761 aatcgcaggt catagtggac tttataaaga taatcttttt gatgatttac cttcagtaaa
     5821 aaagggagaa aagttttata tcaaagttga tggtgagcag cacgcttatc aaatcgatcg
     5881 gattgaggaa gtgcaaaaag acgaactaca aagaaacttt gtcacttact tagaatcaaa
     5941 tcccaatgaa gatcgagtaa cgctaatgac atgtacgcct aaggggatca acacacaccg
     6001 ttttctagtg tatgggaagc gagtaacctt tacaaaatca gaattaaaag atgaagaaaa
     6061 taagaaacaa aaattatctt ggaaatggct tttaggaagt actgtttttc tttcagtcat
     6121 gatcattggt tcgctatttg tttataaaaa gaaaaaataa aggagggtaa ccaacatgag
     6181 aaatagaaaa tggctatttg tttgtgcagc cgctcttttt tctttcactg cctacacaca
     6241 gttgacgttt gcagacagac aagaaagcac ggatagcaca gaacaaacaa tccaaacgtc
     6301 agatagcagc acgattcaaa gcagcgatga aaccgtcgat tcgtcaacag ttgattcttc
     6361 agaagaacct aaaattgctg aagacgatca aatagtcaaa cagaccattc acgttcaaaa
     6421 gattatttct tcagaacaat tagacaacca ggggcatgaa aaacaagaag gagtaaatgg
     6481 cgcgaagttt tctgtttatg atgtatcgga cattttacaa aagatggatg ttaaggatct
     6541 cactactgac caaattgaat cccaattaaa aaatcgagtg aaaaaactat ccagtgatca
     6601 attgaagcta gtttctaatg aagaaacaaa gacaattgat caacaaacag gtgtctttga
     6661 attctcggta gaagtacagg caaatcagaa acaagcttat tatattgtca atgaatcaag
     6721 tcctgaaaac atttctaata gcgaggatat tttgctatta acacctgttt ctgataaaaa
     6781 cggtgaattc ttaaaggatg tgtggatcta tcctaaatca gaagcttcgc aacctaaaga
     6841 agaagtaaaa aaaatcgttt ctactggcgt aaagaaaaac ttctttgaga attgttggga
     6901 ttttgttact cacttgtttt ctagagatta aggaagaaat aaaatgaaac tgatcaaatt
     6961 attattattc aatttttctt gtttaaccgc agtctttttg tactgcggtt tattattttc
     7021 taaactatct attttgccaa gctaccaact atacctaatg aggattttaa acataccagc
     7081 tgcttccatg ccgctagata ttatggaaaa gctcattagg aatccattat ttactacgat
     7141 caatttgatc gttattgtcg gaatttcact agtcatttat aaaaaagagg ggatgaaggg
     7201 atgaatttta aacactcgtg gacaagacgg ttaaaatatg tttttcccat aatgatgatg
     7261 ttaggtacat tgtttgggtt aaaaacagcc aatgtctttg ctgaaaaagt tattgtcgat
     7321 ccgtcaaatc caatccagaa cgtaaagaat aattttatta ttccaaaaga tgttcctaat
     7381 gcaaaaacaa atattactgt aaacggagcg tcaaaagttt acaaatatca tgttgatgcc
     7441 aacaaaggtg gttttacaga cgactacgta ggattagtgg agggaaacaa aaatatacgc
     7501 tatccttctt tccaaaaaga atacggtgaa acaaaccttg ttttagaagg cgtaacaacc
     7561 aacaccaaag tcaatattga ctatggaaaa atcggtacgt ataacgggaa aaaagtcaat
     7621 atcaagctag ttctatctaa tattcactta tactcggata cgttgccgtg gaatctacta
     7681 gataacaact atacaaaaac tcattttcga gacgatggct ataaaaatac gaatggtgca
     7741 atgagtaaat ctaaaaaaag aacagtactt tggatctcag acaatctttt ctcaggaatt
     7801 gtttaccatt caacacaaat gaatgtgcag ctagtagcca catatgagga cggtagcccc
     7861 gttcaatttt caggagatac atttatcagt tttaactctt tgaaccctgc aggaggaaaa
     7921 agcacggatc ttaaaggaga atatgcccac tatgacaaaa tgaatacgac agattggtat
     7981 gtcagaaaag atacggttct ttcagaattt aaatctttct acaacaatct gaacgtggta
     8041 ggtggccacc caggaggaag ctctaagctg acacaagcgg ataatgattt caataatttg
     8101 catgataaat taggagatcc gaagtttggt caaggtactg tgtcctttaa aatatctgaa
     8161 gcaaatccga cgtttgtgat tggttcttct aatgttcaaa cctggtttac tttatcttct
     8221 gcgacaatct ttagtgttgt tcctgatcaa cctgaaaaaa caggggttga taaaaatgga
     8281 aataacgtga acgataaaat gttgcaagta ggagacacga ttcaatatcg aatcaaacag
     8341 aaggtgaatc gattaggagt ggatttacta gcggtttacg atcgatttga gttaatcgat
     8401 aatttaccaa aagaagtaaa ttacgtcgat gcacacgttg aaagtggtac aaataaaaaa
     8461 ttcgatgtat ctggtgaagt gacctatgac aaaacaaaac accaggtaaa atatgcagcg
     8521 aaagctgata cattaaaaaa tcgaatgaag tataacggcg aaacttacga attagtgatc
     8581 aatgtaaaag tcaatgaatt ggccaatcaa aatagtgtag ccaaaaatca gggaacgtcg
     8641 atcattaata aagtagaaaa ggatacaaat atcattaccg tttatttccc taaaattcca
     8701 gtgaaagaag tacaacaaaa tggaaaagat gtaaacggac gaaatgacgg taagaagggt
     8761 acgccgacag ctcctttaaa cgcaggatct gaagtacaat atctagtcac acaaaaatgg
     8821 cacacaaaag gcgtagacgc tgcgtcagat cactacaaac aatttagtat tcaagatcca
     8881 attgaagctc gtttgacata taaagaaggt tctgcgcaag taatagataa gagtaaagga
     8941 aaagatatta cttctgaagg cacactaacc tatgatagca attcaagaac gctgaagtgg
     9001 gaagcttccg ctgacttctt aagtaacaat cttttagatg gacgagaaat tcagctgata
     9061 tttacagcta aaactccatt acaatcagaa aaaaatattg ataaccaagc cgtagtagca
     9121 gtagataatg tttctaataa aacaaatgtt gtgacaattg gggttgatcc taacttgcca
     9181 caggtcattg ttcctaaaac aggttctaca catttagtaa cgatttcagc ggtcagctta
     9241 ctattacttg tgttagcaac ttttagttat gcggttctga gatacattta aaataaaaaa
     9301 acgaaagaat gaataaaatg aaaaagttaa taatagtagt tacttccttg attgccatga
     9361 ttgttatttt agtcggatgt agtaatgaaa aaaataaaca aactaatcaa gataatggcg
     9421 tattgaaatc aggaactatg tggaaagaag aagtaggtgg tcttgtttat aatttgaaaa
     9481 ttatagacga gactacctgg gaatactctg agagtgtatg gcatccagat cctgtacaaa
     9541 taacagtcaa gaggcaaaaa gactataaag gtttagaaag atacaaaata gtagattcag
     9601 ctggtgttag ggaatttata aacaaatctg attctttatt tattgttgtt ccctatgaga
     9661 agaatggcgt aaaaaaaata atttttcttg gatctagcaa ggatgaaaag cgaacgaaag
     9721 agaaattgat tcacgatgga tcacaatcca ataaatataa gttacaaaag actagcgagt
     9781 gattgctagt ctttttattt gtcctgaagg aggaatcaca gtggcaaaag ctaaaacgcc
     9841 atttgaaaaa gccgcgtcta aaatcttaga acgccgcggt gtatctgaaa cacagtggaa
     9901 acaagaagtc cttgaaaaag cacaatttga cctattacgg ggaaaagaca aggacttaga
     9961 aggatatatc tatcaacgtg aacgtgaaaa gcttgttttc gatgaaatta ttaaacacta
    10021 aaaggagcga acaattttat gtttgaatca attacaatga attttttaac acaaccgaaa
    10081 gtagtagctg cggttgatat ttttagagca ttacaaactg ccgcaactag tttaaaaaac
    10141 aatctgatga tttttgctgc tgctgcggcc gttgcttcca ttgttattgg gggtcttttc
    10201 ttcctatttg gacgaagagg agctgaaaat gggaagatgc acgtaggcta tgtattgatg
    10261 ggggtaggag ttattttagc agcagcttct attgtggttt cgttatttgg attgtttgga
    10321 caaacacctc aaggattata agaaagtaaa aaagtaggag taagaagtag tcgatacttt
    10381 ttactccttt tttatgaaag gagaatactc atgtacttta cgattgcagg caataccaaa
    10441 acagataaag agttaataaa aaaagcaacg aaggaagtag gaaagcgtac ttctttttta
    10501 ccgaaaacaa ttaaatattc tgtcattgaa acggaagaac agctacatgt gttagggaaa
    10561 gtactggaac acgaaagtcg atcttctgtt aagttgactc tcacgttaca tgacacagaa
    10621 ggaaaaatag agaaagctgg tacagaatac gtttttggcc cactggatta tcaaatttca
    10681 gaaggtttct atcctacatt gatggattta atccgccttg atgtgtttaa agaaacggat
    10741 gaaactatga gtgtggaaga gtcttatcga aacgaaaaac ttttacaagt tttagaagaa
    10801 gagttagaga gcgaccaaag aaaagtgaat caagggagtg aagtcgaagt aaatgaagaa
    10861 gtaccatggg aacgaccaat atttccaaag aaggagtcaa aagaaaaaga gacagtctat
    10921 gttgacgaac aagctgatat tccgactcag aaatcgatat ttgaggaaga gaacgatgtg
    10981 atgggtcaat tggaggtaga tccctttgaa gaaacaatgg aggatgaaga gacggccgaa
    11041 gtagaagttg atccagttga agcgaatgaa gagtcaacat ggactgaagg ggattctcag
    11101 gaatatattg aaccacttat cagtgaagaa gtagaaaaaa acgaaataga gatacaaaag
    11161 gcaactgtat ttgattatat tttggatcaa tatccgccag agcatgaatg gatgaaagaa
    11221 aaaaacaaat tatttttaaa tgagctttat tcgaaatatc aattacccca aacctatcaa
    11281 gcatttttag agagtaaaga agaattaatc tcacagggta aaggcacact tttagaacag
    11341 ttagagtctg tccaatcaac aaattggcat gagcttgcac aagaagattt attagccacc
    11401 tttgaagaac gtcaacaaga aacagatcaa gaaattaatg agtatgcgac ggaacagtcg
    11461 tctaattggg agaaagcaaa agaggaacta aataaagaag aacagcgagt gattgaagaa
    11521 gaagtacaaa aaattaaaga gcgatacgaa aagaaacgcg acaatgcgta ttccttgtgt
    11581 gtagcaaaga tcaataattt tactcagacg aatcaagaag cgttatcgaa agaaaaagaa
    11641 aacttgttaa aagaacgtat taaagaacga aaagaagaat tttaccgagg tttgcgtaca
    11701 gataagctaa agattagcaa agaattaaat gaacaactga ataagctata tcaaacaacg
    11761 actgaagttc ttatggaaaa atacgaaaag atccagcaag aattacaagt gcaaattcca
    11821 aaatggaaaa aagagtatga aattcaacaa caagaattga aagaacaaga agaaaaacaa
    11881 cggcaaaaag aaaaagagcg cgaacaatta gaactaaaaa aacgtgaaca ggatcttgcg
    11941 gaacaacaaa tggcaataga aaaacaacgg ttaaaccaag aaaaggaaaa agaagcagct
    12001 gctcgtaagg aacgtcaaga acaaatggat acattgcgac aagctcagtt aaattatcta
    12061 gcacaacctc aaccaacgcc ttcagtagct gctgttcaaa ccccaatgaa caaccaaaca
    12121 aatctaactc cttcaccaca gcgttccttt aacggatgga tggtgggatg tattgcaagt
    12181 ttaagcttgc ttctaggtgg aggaacagta tttgctttta atcatatcaa tcaatcttca
    12241 caggctgatt ctgtggccac aacgacgtca atcaaggaag aagcccaaga acaagcaaga
    12301 aaagagtatg aacaacaatt agaagaatta ttgaatcgta ccaatcagtc aacaacagag
    12361 tcaagcatgg aaaatagcaa agagagtgat tctagtaagg ctaaagaagg atcaagcgat
    12421 tcaactgtac aatcaaacac ttccgaaagt tcagaatcaa atgaggtgaa ataatgcgtg
    12481 ttagagaaac aacgaagcga aaagacaaac gattcaattt agaaaagaat aggtatcttt
    12541 ctcatttcta tcgctatact ccctcaggag aagagctacc agaaaaacat gacaaacgca
    12601 tttcgaaaaa gattttttat agtggacttg tatacctccc tttagagtat ttagtaacaa
    12661 gagtaccaga agttttcaac cgattggaaa ttgttaaggg aagcttacaa ggaataaatc
    12721 tgtttcaatt acaggaaatg ccacaggtct ttcattttga ttcagctggt ttttggaatc
    12781 catttactcc tacaactagt ttgggtacac gtttagcaat ttcgacagtt tgtgtggttc
    12841 cagctgtact tatgggattg aaaatggaca tgtggtttcg tcctctagca gatggacaaa
    12901 aaggggataa tcgattaatg accttaaaag aaatccaaca gatttatccg caaatacctg
    12961 aaacaaaaac tacttttcca ggttatggag gtattccaat cacacattac aaaaaatatt
    13021 ggtacattca aacagatact gttaatacgt gtattgttgg tacctctcga tcagggaaag
    13081 gtcagattga agtgttagcc accattgaca atttatctcg tgcagaaaaa caaagttcaa
    13141 tggtcgttaa tgatccaaaa acagaattat atgttggtag taaagatgaa ctagaagcta
    13201 gagggtatga tgtatatgcc tttaatatca ccgatccact gcaatcaatg agtgataatc
    13261 cattggcact catcgtgaaa tactggaaac gaggagacat agatactgca acacagttaa
    13321 ccaatacttt cacaaatacg atttattatg atgccaacgc ttcagataac aaatacttta
    13381 acgaaaacgc gcagaaagct gtcaatgcgc ttatttttgc gttgttagaa caagctgatc
    13441 aaacaggaga ttactccaaa ttgacaccga ataatctcgt tgagcttctt tctgagattg
    13501 gcggttttaa ttattatcca gatccagaca atgaattcaa acagttgaat gccttagatg
    13561 aatttatgaa tcagttgcca cctggaaaca ttgcaaaaaa acaatatggg gcaacgaaaa
    13621 ttggatctga taaagcgaag ggaaatattt tatcaacggc aatcacggga ttgaatccat
    13681 ttactctaac gaaaattgca aagatgactt ctcaatcaac gattgattat aaatcggttg
    13741 ggtttccaaa atacttagat ttgaaattac atgaaagtct tttaaatcaa cgagtcgtag
    13801 tagaatttta tcataaggga aagaaatttc atgaagaacg tgtcaaagta ggctataaag
    13861 gattttgtga aatcaatttt gattgtcatt tagttgcagg tgatcaagtt tgtttaaaat
    13921 acgatcatca aggaaaagaa tatgtggctt ggtatgaatt ttctcaaaga gtattgaaag
    13981 acgaagaggg taatatcgtt tatcggaaaa aacgaggaga aacccatttg ccagaattag
    14041 aaaaagaagc cgttctaaca ttagatgagg agaaaagtaa cttattagta gagtctattc
    14101 ggatgcacta taccgataaa ccaatggcta tttttatgct tacacctgat tatgatccat
    14161 ctaaccatat cattgttagt atttttctta gtcagttata taaagaatta tctacgcaat
    14221 gtgttaagac taaaggagat aaatgtcacc gcaggattca ttttatttta gatgaatttg
    14281 ggaatatgcc accaatggat aatatggaag gaatcatgac ggtcacagct ggccgaaaca
    14341 tgttgtggga tctgtttatt caatcttatc agcaacttta tgcgaagtat ggagaacaaa
    14401 acgcagcgat tatcaaagaa aattgtcaga cacatattta tattatgtcg acagatgata
    14461 ataccatcga agaattttct aaaaaagtgg ggaataagac ggttgaacaa gagaacagta
    14521 ccatcaattc attaggtatg aatactcata tcaatcgcaa tgttgattca gatcgtatct
    14581 taactcctga aagaatttct acttttttag aaggtgaaac gattgtactc gctcctttaa
    14641 aacgacaaga tttgaaaggt cataaaatac ggccgtatcc tatttttaat catggggaaa
    14701 cgaatcttcc ttatgcttat caatatattg aagatttcaa tccatcgtgg gatatcaatg
    14761 atatagacat acattgtaca catgcggact tggatcttaa ggctttacaa attgattatg
    14821 attatttcct accagatgaa tatgctagaa atctctatca tggactgcat gatcaattag
    14881 aagaaaaaaa cgaagaaaat atgttttata aaatcgttca atctcttgag aatgagacgg
    14941 ctaaaaaatt gttaattcaa ttttacgaag aacaagcagc agatcgactt caagaatatg
    15001 ttgaaaagtt gatcaaaaat aaagaaattt ctgaaatgat tgggaaacgg ttgttattgg
    15061 aatctgaaaa ggtggtgaaa gaatgatcat tggaggaatt ttttctggca tagccgactg
    15121 gtggtcaggc ttattcggag aaggggatgc aaaccccaaa accgtaacga aagtcttaca
    15181 agattatggt aattatctgc agtatcaaga tgtatttagt tggatttgga acacttttct
    15241 gtggggattg attaaaggat tatataatct caatacttta ctagaaaaaa ccatttatca
    15301 aagctttgat ttaaaagact tattgaacgc cgctggggta aatgcactat ttcaaagttt
    15361 gattagtaag gtattggctc ttttttgtgt cgtcacatta atttatttag gcttgaaatt
    15421 ttttatgagt aaacacccac caaaagtcaa aaatatcttg gttaatttat ttatggccat
    15481 gatcttgatt tttggtggga gttctttaat cgatgaaggg ttaaatatca gtaaaagctt
    15541 ttacggagac gtcactgcag caaataaagc agataaaacg ggttcacctg cttttcaaat
    15601 tattcaaaat aatgtgatcg atgtcagtac attactagca actgacccga ataaagtaga
    15661 atccctgcca acagacaaaa gaaatgcttt aacagcgaaa aattttaaaa cagcgaatat
    15721 caatgggatt attactccta aacaagctaa agaaatggcg gataaagata agagtggttt
    15781 atcagattta caaaaggatc ggttaagagc gttacaatac cgattggaac tagatgataa
    15841 tgggaaagaa attcctgttc aaattagtga cgaaggctta gcaaaatatg tctatacttc
    15901 agggtatcgt cgatacagta gtaaaccagg tattatctta gctggtgaat cttctttggc
    15961 ggtggcctat ttatttatcc tatttacgat cgttacttgc attattgagc tggtatttaa
    16021 aaaattctat ttagtgattg ccgcgtcaac ggactttgag acaggccaac ggatgaaaag
    16081 tgcgatagaa gatatttctc aatccttctt gttattggcg tttacgattt tagaattacg
    16141 aatctataca ttaatgcttt caggtatcgg tgatttgcat gcggcaggaa agatcaatgg
    16201 attcttgtat gttgttgctt taattgtgct aactattgcg ctattcaaag gctctcaatc
    16261 ggttacgaag attttcggtg ttgatacgag tctgaaaaac ggcagtaatt ctcttcttag
    16321 catgtttgcc ttaggaaata ttgcgaaaaa tgtgggtagc ggagctaaaa accttgcaag
    16381 tgctggtaag agtggtttaa gccatttaaa tgatattcgt aaaaatggat ttggccatcg
    16441 aaaagatgtt acccctgata acggggaaga acaatcagac gataaagcta caactgtacc
    16501 taatagtaag aaaacagttt ccgaaatgtt cgggaaagcg aaaaatggtg tttctaaagc
    16561 cgcagaaggt cttggttacg tcaatgaacg tgggttaaaa ggaacagctg aagatcttac
    16621 agaaaaagcc aaagacacct tagaagagaa attagacggc acgagagcta aagaattggc
    16681 tgaagctgtg aagaatccat ccgaagcact agaaaaacaa aaagaaaaag cttcagaagt
    16741 caaagaagga ctaaaagatg cgtatggtga aggacaagtt aatgcagcag taaaagctaa
    16801 tacaacaacc gaaaaagaaa atcaagaagg tatagtgatt ccttcagtca aagatcacca
    16861 agaagcgttg cactctaatg aaaattcgat tgaagagaaa aattccatag aagaaagaaa
    16921 ttcagaagaa ggaaaaaatg gacagttacc aaaaactgat ccagaacaat atcgctataa
    16981 acctaacagt gaccttgaaa atgagaagcg aatttcagat ttatcaaaag taaatcaaga
    17041 agacaaagca gaaaatgagg gacagttacc aaaaactgat ccagaacaat atcggtatag
    17101 atctgttaac tccgaaaatg aaaaacgcat ttcagattta ccaaaacgaa atcaagaagt
    17161 acaaacggat gaggattcca tcgttctgcc aaatgataat ggaatcgaag ttggaactga
    17221 aaaatcaacg aaaattggtt tacctaaggc acaaaattta ccaatgaaag atagtcgttt
    17281 gaatcaattc aaggagaatg atcaaagctt tgttcaccaa tcaactgcag gtactgttca
    17341 aatgaaacca agtcgtttgc ctgaaaatgg aaatctgaca actgtttctt acaatttatc
    17401 tgaaagtggt gagacaggga atgcgtccgt tcaaaatgtt gtgacaagag aagctgcacc
    17461 aaaacctatt caaaacgttc atacaggtta caagccagca aatgtggcat ttactgcacc
    17521 aacaaaaata aatgtgacaa gagaaactaa aaacaggaac aatgcattga aagaacaact
    17581 attgagggat atcaaacagg atatcaaacc ataaaaggcc tacaagttag gccttttatt
    17641 tatatgaaaa ggagaaatca attatggata aatatataaa catgaaaaac cctccaagat
    17701 ttagtggaga atggaagttt ttcgcttttt tctttttaga tctattaacg cttggtggct
    17761 gctttttttg ggcgaaaatg gtcaataatc ttgtccactt accactcttt tttgcactct
    17821 tgaattatgg cttatggatt gcgatagcgt tagtgattgt ttggcgaccc tataataacc
    17881 caggtcaacg acaaattttt gcgattatcg agtctatttt ttttgcggac aagaaccatt
    17941 atcatgcgtt agatcctaac cgaaattatc atggtacgta taaggaggat gaataaatgc
    18001 gagtcaaagg acaaaattca gttgaaagga aatccatttt gcagtttgga aaaccagaag
    18061 agcgctctat cttggactta tttccgtata aatcctgtac agaagaggga gtcttaatta
    18121 ctagagaaga tcattttcaa cgttattatc gtgtagtttc tacagacgtg gaaggattaa
    18181 atgaacaaga gaaactagaa cgaatgaatc agttgaccac cgtcatgcgt acgtatgtgc
    18241 caacaattaa gttagttagt ttgaccacag agacggatct aacggaacaa atcgtgcaaa
    18301 agcggcaatt attagataaa aatcgtatgg aacagtcctt aggaagaaat ctacaacgat
    18361 taaaaaaata tgaaaagaaa ttagtcgaag aaatccagga attgaaacga gcagaacaag
    18421 aacgtcctga cttaagcttc tttttcgtca ttgaaggaaa gacaatcaag gatttacaaa
    18481 ccagaaaccg tcagttaatg cgatctagtg gcattttagg gttaaaacca ctctacaaaa
    18541 aagaattgat caagattctg tatcgaatga acaatatgaa tgatgagtag gaatggagaa
    18601 gagagaatga aatatccgtt gatatggtta gaaaaagatg ttccgaagga agagaccact
    18661 agaaaatttc ctcacacttt aagcctgggt aagttgggaa aagggcaatc ttttaaccaa
    18721 gtaaagaatc aaacaagaag aggtgactgt acatgttaga agcaattaaa acagcttttt
    18781 caccacaaaa tgatcaaaaa gtacttgatc cattaaagca actaggaaat cgggaaatag
    18841 aaattttaaa atccaaaggg tatgatttag attttttaaa acaagtgatg ccacaaggtg
    18901 ggttaaattt tgatgaagaa tatgtgacgt atggtaatgg ttattcacga tgtgtgacag
    18961 tttatcacta cacaaaaaat cctacgcttt tttggttggc caatctcatg aacaatcctc
    19021 atacagtggc cacactcgat gttagcacag atgaaaagca aaaagtgatt gatcaaatca
    19081 atcgtgcctt agatgaatta aatgatcgat cagataatga acgaaaagcg actgaccgaa
    19141 ataaaagcgc agaagaatac ctggaactag cggaatatgc tcgtaaattg acttctaatg
    19201 gggaaatttc taagcaagtc aaagtgagag tacatgttta cggaaacacg attcaagaag
    19261 tagatgaacg agcgcaggaa ctgatcgaaa atctaaaagg gatggattat cgtgcggtga
    19321 cttatctgca taaaaccaaa cgagattggc aatcgatgtt taccatgttc gatgaacaag
    19381 ctgaatggtt cggaaatatc aaagggcaat cactaccatc gttaaacatt ggcggaggtt
    19441 tcccgttcca ccaccaaacg ctaaaagatc caggagggac acaatatggg gaaaccatga
    19501 caggcggccc atttgtctgg aatgcgacgt ataaaaatag tgtacggttg tctactaata
    19561 ccttgcttct aggaatgatg ggagctggta aatcgaccgt tcttaaaatg atcgcggaag
    19621 cccatttagc tgcaggagac tttatttggg gctttgaaaa gggaaaagac tttattcctt
    19681 tcttaaagga atataacggt attatggtgc gtttagacgg atctgacgga atgatcaatc
    19741 ctttagagat atttgccaca cggacgtatg atgaagcatc cagtttatat gacgatggat
    19801 cagtcaaaga tttgaagatc aatgaagcag cgtcctatca aacacactta gacaaagtgg
    19861 tctatcaggt acagttagtg agtcctcagc taaaaggaac gatgaaagca gaatttaaga
    19921 cctacttaaa tcgtttttat gaagagtatg gaacagtacc acgcggcttt acttcctcaa
    19981 attcgcgttc aaatacggag acgcaagtca caggtaaaga tccagaagct tatccgacgt
    20041 tcaaagaatt tttagacttt ttaggacaac tggaattacc aggtgcttcc caagagaaaa
    20101 agaatcgaaa agaagaaatg gaatccatcg tagaatcctt atgtgagacg tatggcatga
    20161 tttttgatgg gcatagtacg attcgacacc ttgaccaaca acagttggtc ttttttgaca
    20221 ttgactctat tacaggctta gatcgagggg tacaacaatg tcaaatgtac atggctatga
    20281 cgttgatttg gaatcaggca ttgattcaag gaagaagaca acgacgttta attaaagaaa
    20341 aacaaatgga agaacaagac ttcaaacgct tcttggcgat gattgatgag tgccataatg
    20401 cgattaatcc agattttatt gaaacggtaa attatgtcac aaactttcaa cgagaaatgc
    20461 gtaaagtaga agcaatgact gttttagcta cacaatcccc acaagaaatg gtgccagaaa
    20521 atatgtcttc tgataacttc tcgaaactga agaaagtctt tgaattttct tctacgaaga
    20581 tctttatgcg tatggatgaa tctattttac gtcatataga aggattagtg ggtaaatcaa
    20641 tgacgaactc agaattagaa tccattcctc aacaaaatca aggagacgct gtgatcaatt
    20701 ttggctcaaa agaaaccatt cgtgttcatt ttagtccgaa caaacgtcaa ttaaaattgt
    20761 ttgatggagg aaaataatgg aaaaccaaaa tgaaagttta atcaaacagt atgttaagcg
    20821 tcgtgcaaag cggcgcttat ttttgtgggt gtttggtact tctgcaggtt tgattactat
    20881 attgatcact gtgtttgtga ccctttttct aatacttgcg gcaggttcta ttgataattc
    20941 tgattcaagt agtggtggcg aagcttttac aggagaatat tcggaaggct tacccattta
    21001 taaagaaatc aaaggaagag gccctttttc tgatgagatt gcgcaatatg ctgtaggtgc
    21061 agcagtgaag tataaattat taccaagtgt gatcctttcg caatacggtt atgaatcagc
    21121 gtttggtacg tcggcgtccg caagaaatga tctcaattat tttgggatta cgtggtttga
    21181 tgggtgtctg tttcctaaag gaactgcgcg tggaattggt ggcattgaag gtggctggta
    21241 catgaagttt cccaactcaa aagctgcctt ctcctattac ggctttatgg tagccacaca
    21301 atcaaatttt aatgcttgtg tcggaaataa aagccctggc gcaagcttat tgatcttagg
    21361 acgaggaggg tatgccgccg caggaattac tgaagacagt gcctattata aaaattgtat
    21421 gtctattatt aatacaaata aattgatgga gtacgatgag tttgcgatta aacactggag
    21481 agaaggcggc ggaactggtg gtacgattac aggaagctgg ggcaatccat tcccaggaag
    21541 tagcttagat aaaaattcgt tcagtggagg acaacttttt gggaaaaatc caggaggaga
    21601 attccgacct aacgggttcc atgatggact agactttggt tcagtcgatc atccaggaag
    21661 tgagattcat gcggttcatg gcggaaaagt cgtgtacgtt ggcaatcctg gtatttcagg
    21721 tttgggtgcg tgtgtgatcg tgattaatta cgatggcttg aatatggtgt atcaagaatt
    21781 tgcaaatagt acaggaaatt ctcgagtgaa agtaggcgat caagtgaaag ttggtcaagt
    21841 aattgggata cgagatacag cacacttgca tttaggattt actcgaatgg attggcgtca
    21901 agcacaagga catgcattca ttgatgatgg tacatggatc gatccgttac catttttgaa
    21961 tagcagcaaa aaatagatca ggagaaaaaa tatggaaaat aaaaccttaa aaatcgtctt
    22021 aacagctgca attagcgtta gtttaatcgg caatattgcg ttgttttggc agcttaaaga
    22081 agaacaagag acaaatacct ataaaattga agaagtggct aaaaacgcgt ctgataagct
    22141 caaaaaaaat tcttctgagg cacaggcgaa gatcgacaag ttaaatcaaa ccatcaatga
    22201 gaaaaaccaa gaaatcgatc agctgaagca acaagatggc acaaaagcaa aagaggaagt
    22261 aactgaagca caaagaaaga cggcagaaga gttcggtcaa ttggccattg ataaatcatt
    22321 aagcagaaat gaattaacgg aaaaactaaa agatgtcgca acccaagaag tgatcgacaa
    22381 attaagtcct gcagacgatg atcaccaaca tgacgactac ggaagttact cttttacatt
    22441 aggtgacgtg caaacttacg ctcaaacaag cagtgtaaaa gaggaacaaa attttgtcgt
    22501 atttgttgat tatacaatcg gcaatcctca atttaaagat gtcaaaccac aaaaaataaa
    22561 aggtggatta actgtcactg aaaaacaagt agatggtcaa tggaaagtca cagactttag
    22621 ttatttcact cgttaggagg aagaaaatga gtaagaaaaa aggagcaaga caacgtttta
    22681 aaaaacgaaa aagttatctt agatggctgg ggatctttat gattctcggc tttttgattc
    22741 ttgctagtcc gatttacaca cataaaaagg tagacatacc agatgaagta agcacgaacg
    22801 catttttaaa cacgaaggaa ctgacgatgg tttcaaaaga aaaaggagcg aaccagcaat
    22861 tagtttttga atttgcgatc gacgatgaag atcagagctt attaaaagaa ctagctaatc
    22921 ttaattatcg tgtagaagta aagacagcta aaggggatta tcaagcaata aaagccaaag
    22981 tgatcaaggt gtctgatgat tattttgtag tgaagttagc acatgtacca gaagaatata
    23041 tcgccatgcg tttaaccatt attcctgaaa aaattgatcc aaaagtggat atgcaagaac
    23101 cacaagatct gatttattac gttcacgaag ataaggttaa agatcaagtg aaagatgaag
    23161 attatgaaca acatgcgatc aattacaaag tgaaaggata caaaaaagaa caaaaagcag
    23221 cacaaaaaca aatggaatcc ttccaagcaa ccattgattt gaatgaagaa ttagtgaaga
    23281 agctaaaaga tcaattgcct tatcaagtcg cagatgatca ggaaaatact gaaaacaaga
    23341 ttaatagcta ccagcaagaa attgaaacat cgaaaacgca aatgaaagat caagaagaga
    23401 tcattcaaaa acttcaagaa aaaattgatc gtatgacaaa agaaaagatt tagaaggaca
    23461 ggtggagtga aaaaatgaag cgaacaaact tggctgacaa agatactttc gctgagcaga
    23521 aagtattgat taaagcctat ctcaaagttg taaaagctaa agaaatatgt cgagaagtga
    23581 atttatctaa tacaacaata tctgagttga agaatggtcg aaagaattta gatactttaa
    23641 aattcagatc atttgaagct ctatatgtag ctgctaaaaa atattttaca gctgataaca
    23701 aataaaaaac aggagtattt tatgtgaaaa aagtatataa aaaatgctta tgaatcagct
    23761 atatcacctt aaccatttgt taatgagatg ggagaaaaca ttaaccacga ttctaacgca
    23821 aacatcaagc acataaaaca tttaacactc ctcctttctg gctgaagatt tcaaccaaac
    23881 aggaagacag cgtatcaatt atagcataca ctttttctta aattcatttt tcatatgaca
    23941 aaatatttcc ttctaatcga caaagttaga aggatttttt attgtctaaa tacacaaata
    24001 accttaattt ataaagagca taaggaaacg tgggaacact ttttaaaaaa agtgttccaa
    24061 taggctgtgc ctattacgtt tctcaaaaat aattgtggga acaaaatatt taaaaatagg
    24121 atagtgaaag gatagcaaag gatagtaaaa ggatagaagc aggatagcga aaaggatagg
    24181 ctccttttcg ctatcctttt taaattggag gaattaatat ggaagtaaga ataagaaatg
    24241 tagatgagaa aatcgtaaga gaaattgatc gaagatgtga cgaactaagt aaccgaacgg
    24301 gtaataaatg gagtcgtaac gattatttaa agctactcgt tgaaaatgat tttgatcgtc
    24361 ctttgatgga atataaacaa gataaatttg atcaattatt aaatcagtta atagataaat
    24421 tttcttttgt tcaaagtcat aatacaaaag tattagaaga atatatttgt cagaataatc
    24481 aaattatcga acttttaatt gaacaaagta gaggaggaga agtttaacat ggccaaagtt
    24541 atagacaagc atatttattt ttatgaaaca catatagatg ttctagatga aattattgca
    24601 actcatgcag aggttaaaaa ctatagtgaa gccgttcggt ttctatgtat gaattatgat
    24661 tcagaagtgg agaaaaaagt aaattccaat caagcaaagt tgaatgcaat gggaaaagaa
    24721 atttctattt taaccgaaat ggtttcagag tttgcggatc tccatttgaa agatacaggg
    24781 attttaattg gtacaaattc aactgtttac caagaagcaa aagagcgtgt ggaaggcaag
    24841 ataaaagcaa atcaaacgaa gaaatattct cctaagataa agaaaacaat aagcgaatca
    24901 gtgactacaa aaagtgaagt atttgatcca acaaggttct taaaacgata aaaattagaa
    24961 ggagaatgtg atgagtaaat cacctgcagt cattctcact tgtcaattta ccttgcccaa
    25021 taaaaaatct ttttcaacat acattgatta tatgacaaga gaaaaagcgc tggaagaaaa
    25081 ggaacgacgt acgcccgagg aagaacagga actgcgtcta ataaagaatg ctttagagga
    25141 tttttatatt cctgaaggag aaactttttc ggagagtaag acgggtaaag aattcagcga
    25201 aacgtcgaat gaagcgcaat cgttgatgaa acatggaatc aattttgaca agttagaaga
    25261 acaagatttt accaaatatc tttcttatat gacacgtcac tatgcgttag aacaaaagaa
    25321 agtactgacg catagtgaac aaaaagaata ccaacgcttg aaccaagcaa taaaaaaata
    25381 tcaaacagag ccacacaaaa aagcttcagg aaatcttcct ggagtttttt ctatggcttc
    25441 agacgaagtg aaaggaagtg atctgaagga gatcaagcaa accttccaaa gaggacaaca
    25501 aaaaggctca atcatttatc aagatgttgt ctctcatgat cattcgtatc ttgaaaaaat
    25561 aggattgtac gatcccaaaa cagatacttt agatgaagaa ggtttaaaag cagctggaag
    25621 aaaaatgatg gagacattgt tcgagaaaga gcaactgaat gaaacaggct actggatggc
    25681 aacgattcac cgaaatacca aacatatcca tattcatttt gcagttgttg aaaaaaaaaa
    25741 tacgcgtaaa ccatacactg agattgaaaa tggtgtgagt tatatcgtac cgaaagggaa
    25801 gagaaggcaa gcaacattag acgaaatgaa gactaattat gtacatgagt tagaacgttt
    25861 ttcttatgaa aaaaatcgaa tgggtatgga gaaacgaaat ttattgacac ggaaaagtga
    25921 tttgcgtaac accttaacca aagtagtgaa agagccagta cgttatgatc gacacgcaat
    25981 gagcttatta actgaagtat ataaaaactt acctaaaaag cgttcggaat ggcattacgg
    26041 ggatgaaaat cgaaccaaac tttcaccata cacaagagag aaactcgatg agttaaccca
    26101 atatgtgtta acaaaagaac ctggatatca agaatatata cagatttcaa aagcattgaa
    26161 agaagaagca aaaagtcttt atggggaaag caagagagaa tcaaaggatg cagaaaaaaa
    26221 tgctctcttt gatttaaaaa agcgcacagg aaatgccatt ctaacagaac tgaagaaaca
    26281 ggatagtcaa ataaaacctt taatagaaag gatggatcag atgcaatcta tttacaatga
    26341 acgatccttt cgaacactta aacagttgcc aacgaatgaa tacaaatata gttacgaaga
    26401 attcatgaag cgcaggaaac aattccaaca aagagttgtc acgcaacgga gtttgcgtca
    26461 attaaatcga acgattaatg cccatgaaga aaaataccac gcaagtaaag catacgaaga
    26521 gcaacaacga agaattcaaa tggaacaaga aagacagtag gaggaatagc aatgaaacaa
    26581 tatttagatc aatggaaagt tatagaagga tcattaagag aagaacgaat cgaacaactt
    26641 cccgattgtt tagaaaaaga gcatttgttt cagataagag aaatgttgat aaacgaacag
    26701 tttgatccaa atcaattttt agtcgttgag tacccagcta ctggtgtgta ctgttgtaat
    26761 catgtgaagg gtgaaaaata ttttatcatt caagaatatg agggcaagtt agcgccttat
    26821 tatactactt gggaaatgaa tgaagagggg atcaataact tcccgtgtaa aagcattgaa
    26881 gagtctattt cactcacaga atgttagttg ttaagtgaat aaaagaagta aaagagtcct
    26941 gaacgtgatt gtccaggact cttttttttc actgaattgt tttccgccaa ttcattgagt
    27001 ggtgcgattt ccgtctacat tatatcaaaa gaaaggagga agaagaaatg gcttattcaa
    27061 cgattggagt tgttgttgaa aaaagcagag acaatcttgt ttttgtgaca gaaattcaaa
    27121 caggcagagc ttttgtagtc acagacaaag cggcaaaagc atatcaaagt ggcgatattt
    27181 taacgttaaa tctgactacg aagacgttcg tcgatgcggc agaagattat ccatt
//
LOCUS       DACCVZ010000033        26768 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.033, whole genome shotgun sequence.
ACCESSION   DACCVZ010000033 DACCVZ010000000
VERSION     DACCVZ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.033"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(26..1957)
                     /locus_tag="IVW63_001427"
     CDS             complement(26..1957)
                     /locus_tag="IVW63_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP7859708.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="IVW63_001428"
     CDS             complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="IVW63_001428"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAP7859709.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2886..3638)
                     /locus_tag="IVW63_001429"
     CDS             complement(2886..3638)
                     /locus_tag="IVW63_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP7859710.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3798..4007)
                     /locus_tag="IVW63_001430"
     CDS             complement(3798..4007)
                     /locus_tag="IVW63_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859711.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4018..5345)
                     /locus_tag="IVW63_001431"
                     /pseudo
     CDS             complement(4018..5345)
                     /locus_tag="IVW63_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5710..6297)
                     /locus_tag="IVW63_001432"
     CDS             complement(5710..6297)
                     /locus_tag="IVW63_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAP7859712.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(6380..7630)
                     /gene="clpX"
                     /locus_tag="IVW63_001433"
     CDS             complement(6380..7630)
                     /gene="clpX"
                     /locus_tag="IVW63_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAP7859713.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(7877..9166)
                     /locus_tag="IVW63_001434"
     CDS             complement(7877..9166)
                     /locus_tag="IVW63_001434"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAP7859714.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(9320..10252)
                     /locus_tag="IVW63_001435"
     CDS             complement(9320..10252)
                     /locus_tag="IVW63_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859715.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(10409..11068)
                     /locus_tag="IVW63_001436"
     CDS             complement(10409..11068)
                     /locus_tag="IVW63_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAP7859716.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(11071..12096)
                     /gene="sppA"
                     /locus_tag="IVW63_001437"
     CDS             complement(11071..12096)
                     /gene="sppA"
                     /locus_tag="IVW63_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAP7859717.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(12109..12399)
                     /locus_tag="IVW63_001438"
     CDS             complement(12109..12399)
                     /locus_tag="IVW63_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859718.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12808..14613
                     /gene="glmS"
                     /locus_tag="IVW63_001439"
     CDS             12808..14613
                     /gene="glmS"
                     /locus_tag="IVW63_001439"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAP7859719.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(14685..16040)
                     /locus_tag="IVW63_001440"
     CDS             complement(14685..16040)
                     /locus_tag="IVW63_001440"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAP7859720.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(16064..17233)
                     /locus_tag="IVW63_001441"
     CDS             complement(16064..17233)
                     /locus_tag="IVW63_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859721.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(17230..18117)
                     /locus_tag="IVW63_001442"
     CDS             complement(17230..18117)
                     /locus_tag="IVW63_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAP7859722.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(18306..21998)
                     /gene="nifJ"
                     /locus_tag="IVW63_001443"
     CDS             complement(18306..21998)
                     /gene="nifJ"
                     /locus_tag="IVW63_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAP7859723.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            22197..22718
                     /locus_tag="IVW63_001444"
     CDS             22197..22718
                     /locus_tag="IVW63_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAP7859724.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(23417..23974)
                     /locus_tag="IVW63_001445"
     CDS             complement(23417..23974)
                     /locus_tag="IVW63_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859725.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(24153..24764)
                     /locus_tag="IVW63_001446"
     CDS             complement(24153..24764)
                     /locus_tag="IVW63_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859726.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(24877..25134)
                     /locus_tag="IVW63_001447"
     CDS             complement(24877..25134)
                     /locus_tag="IVW63_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859727.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(25731..26009)
                     /locus_tag="IVW63_001448"
     CDS             complement(25731..26009)
                     /locus_tag="IVW63_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859728.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(26043..26294)
                     /locus_tag="IVW63_001449"
     CDS             complement(26043..26294)
                     /locus_tag="IVW63_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859729.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         7558 a         5767 c         4585 g         8858 t
ORIGIN      
        1 aaacccagcc tcttcttttt tatttctatg cttctgctac tgcaggagct tttctcaata
       61 aaccataaat cacaccagat acgactgctc cgatagcaat aaacaccaaa tacatgaccg
      121 ggtgactcag taagaataca acgaaaatcc cgccgtgagg agccagtaat ttgattccga
      181 aagctccgac taatccgcca gttaaagcag aaccaataat aaaacttgga atggcacgaa
      241 tcgggtcagc tgctgcaaat ggaatcgatc cttccgtgac aaacgatagt cccatcacga
      301 tgttcgtcaa accagcatct tgatctgttt tgctgaattt attcttaaac aaacgtgtag
      361 caacgaaaat tgccaatgga ggtaccattc ctccagccat aacagaagcc atcacgacac
      421 ttccgccagt tgcaacagtc gtagctaaag ttgctgtacc aaacacataa gcggctttgt
      481 tgattggacc gcctaaatct gccgccatca ttccagctaa taatgcacca agtaaagcag
      541 cattcgaacc actcatactt gtcaagaaac cgttcaatgc atcattgatt gctttcatag
      601 ggacattgac cagcaacatc aagaaaccag taatcagtaa gccaaacact ggataaaaga
      661 ggatcgtttt aattccatcc aatgattttg gtaagttctt gaataattta cgtaaaaata
      721 cgatgacata accagctaag aatccaccaa tcagtgcacc taagaatcct gcaccgcctg
      781 tattagctaa tgcaccagca gcaaatccaa cgatcaaacc agggcggtca ccgatacttg
      841 aagcaataaa tcctgctaat accggcagca tgaaaccaaa tgcagcttgt ccgatttggt
      901 tgaaccagct agcagcttga ttgtaattcc ctagatttga taattgatca tgtggcacgc
      961 caataaattg gtcgatcatg aaagaaagcg caatagcgat tcctccacca ataacgaaag
     1021 gtaacatgtg tgatacgccg ttcatcaaat ctttgtaaat tctttgtccg atagtaccat
     1081 ccgcatttcc ttcttctgaa ctgctttctt ttccatcacc atggaatact ggtgcagtac
     1141 cactaagggc tagattgatc aactcttctg gtttacggat accatcactg acaggacgat
     1201 tgatcagttc ttttccgtca aagcgattca tctctacttt tttgtctgct gcaacgatta
     1261 caccttctgc acgggcgatg tcttcagcag tcaatcggtt tttgattcct tctgaaccgt
     1321 tcgtttcgac tttgatctcc acacccattt ctttcgcttt tttcttcaaa gcatcttctg
     1381 ccatgtaagt gtgagcgatc cctgttggac aagctgtaac ggcaacaacg aattttcttt
     1441 ctggatgagc agaagcttct gcagcttgtg tttcttgttc tgctttttct tctgcttctt
     1501 tttgctcttc agctgtttgg aacaagtctt ggacttcttc tggtgtattt gcttctttta
     1561 attttcctac gaaatctgca tcaatcagca atcgagatag tgctgctaat gcttgcaaat
     1621 gtgtgtcgtt tgcgccttct ggagctgcga tcatgaaaaa cagataagtt ggctgtccgt
     1681 ctaaggcttc ataatctact cctttttggc tttttgcgaa taaaactgtt gcttctttaa
     1741 ctgcactgtt tttcgcgtga ggcatggcga ttccatcacc aagacctgta gaagtttgtg
     1801 cttcgcgggc tagaattcct tctttatatg tttcgatatc ggaaatccgg ccggcatcaa
     1861 acattttttg gaccatttca tcgattgcgc cttttttatc agtcgcttgc aaatccatga
     1921 tcatcgcttc tttgaccatt aaatccttga tattcatgat tatcctcctt gaaactaatc
     1981 aatttttgtg atttcaactt ctggcagcaa ctcatcaatc aattcgcgag ctgccaagtc
     2041 atcagaaaaa gctgttgcgc ttccgcaagc aactccccat ttaaaggctt cgattggatc
     2101 tttcgtacgg ctgtaagccc caataaagcc agcaatcatt gaatcccctg cacctactga
     2161 atttttcaat gggcgaacta atacattcgt tttataagtt ccttgttccg tgaagagcaa
     2221 agcaccgtct ccagccattg agatcagcac attctgtgcc ccttcagcta gtaatttttt
     2281 cccatacgga atgatttctt ctacagattg gaaggttgtg ttgtaaagct cagctaattc
     2341 gtgattgttt ggtttgatca acaacggttt cttaacaagt gcatttttta ggtcatcacc
     2401 tgttgtatca atcacgaaat ctgcaccttt ttctcgaatg atatcaatca gttcttgata
     2461 aaatcctttt cgcaggctag ctggcgcgct tcctgacaat acgacgatat ctccttgtcc
     2521 tactgttcct aatgcttgct tcaactcatc gatttcttca tctgaaatag atgggcctaa
     2581 gccattgatc tcagtttcag tgtctgattt tagtttgata ttgattcttg tatcttcttt
     2641 tacggttgtg aacaaagact ggatttgttc tttttcaagc cacttcgaaa taaattcgcc
     2701 agtgaaccct cctaaaaacc ctagtgctgt agattgagaa tcgatccgtt tcaaaatacg
     2761 ggaaacattg atcccttttc ctccaggtaa cttgaagtct tccttcattc ggttcaaatc
     2821 gcctagtttt aacccatcta cgcgtacgat ataatcaatt gatggattaa gtgttactgt
     2881 gtaaatcatt gtattgcctc cttaattgtt gtcttttcac ggaattcatt aacgaattct
     2941 aatggacaac gctcggttat gatcgtggct gcttccaaag gtgcaacaga ggtgaaggac
     3001 aactggttga atttggtatg atcaatcaat acaaatgtct cttcggaatt tttcatggct
     3061 aaacgtttaa cagctgcctc ttctggatcc ggagtcgtga atccttgttc aagatgggca
     3121 ccgttcattc ccataaatgc tttattaaaa tgaaaatttt ttagttgttc tatcgcatta
     3181 gatcctaaaa cagcattagt tgccagcttt atcgttccac ctaaaataat ggtagcaagc
     3241 tccaaatcaa ctaaatttgc cgcatgttga acggaatttg tcactactgt gatctgtttt
     3301 ccttgcagaa aaggaatcat ttctaacgta gtagagccag cgtctaaata aatgacatct
     3361 tcgtcattaa tggtttcagc tgccgatttg gcgatttgct gtttttcgtg aacgtttttg
     3421 agtgattttt cactcatatt ctgctcaaaa ttcaataatt gctctttctt agctccgcca
     3481 tgaactcttt ctagaaaccc actattctcc agctcttgta aatcacgtct tatcgttgat
     3541 tcagaagcat tcaaaaggtt tacaagatct tgtgatttca cgattttctg ctgttcaagc
     3601 aagtctagga ttttttgtct gcgttcctct gtaagcattt tcacgatcac ctcaatacaa
     3661 ataatagcat attttttttc tactagcaat ataaatcagt caaaaacgtt cataaaaatt
     3721 ataaatcagt caaaaaaaaa ataaaaaacc agtcagaaag actggttttt tatttttttg
     3781 tctatcatca agccgtttta tcgtttttta ttttcgcttc ttgttttttt catataaaca
     3841 gaagcaggtt ttctttcctt atgaagaaga taataataaa gtcccatccc gccaaacatg
     3901 accaaaaaac cgatgactga tcgaatagga aaattaggaa caaaaaagag acagacggat
     3961 aataatgatg ccggaaccat tattcgataa tagagttgtt tatccatttt cttcacctca
     4021 tattttttgt aaagtaatca attgttctaa ttctcggtaa tctaaaaatt gcacacgcag
     4081 atgctgctca cctttcttga catcgaattg gatacttcgc cgctttttct ttattcgttt
     4141 gaaggtaaca tcagagagtc tatgtttgat ttcctttaac ggtaattctg acagggattc
     4201 tgaaggaaca tagattctta aggataaaag atactcttga tatttttcat ctgttacctc
     4261 tacttctaga tattccctaa tataataaca ataagcttcg attccattat ccaaagcaac
     4321 agtcggatcg ataactttat agcacatcat gcgtgatcga ttctcgtcaa cccaaggaaa
     4381 atacgcctga gcatttagtg ttccgcgaac acgcctttct ttataatctc cttgttggat
     4441 atcataactt tttgttacaa aaaatgaagc attcttttta ggaacaggtt gcatttgtgc
     4501 attctgatac tggacagatt ggatcgtatg gtcagtgtaa atgtattcaa cgaatggcgg
     4561 tttcaataaa ccgacaccat tgtcccaagc aagatgatca aacccaagct ggtccctaaa
     4621 ataggattga aacatttgat tgtttggctt ttgccagtta aaggggtctc gataaagctg
     4681 gatacatatg acttcgtttt ctaattcctt cactttttct acttgttgga tgtcgagaaa
     4741 aatcggttta gggatgattt gatgataata gcgactataa tacatttccc aacacgaagt
     4801 gaaacataaa ccttggtaaa aaagatcgta tcctggaaat tggttgcaat cgactactac
     4861 ttccccgttt tgttgtttca ttttaggtaa atgttcgatt tcatcctttt tctcaaacaa
     4921 tagccgttga gagatctgtt ttgtattgtg atagataaac tcgctataag ctcgcatata
     4981 ggcgaacacc ccatgagcaa tcattttttt ctgaatgaag tctcgaatca aaaattgctt
     5041 ttctttgaaa acagagatag acaatacatt ttttatcaat aattgattat cttccaagcg
     5101 aaaactacat tcgttctcgt catttcctac aactaaccaa ctttcgtctc ttaccgatgc
     5161 tagcattatt ttttcttgaa gctttcgaag atcatacgga tccgcttgtt gtgtgaaaga
     5221 gcggataaat gttggctgga tcaacagacg tgtcaaaata gcccaatcgc ttatttcctg
     5281 tttttttctt cttcatttaa gtctgtgagc tggatagtca tcaataattt atcttcgcca
     5341 atcattttct cacctctttc aaatcttttt ataatttaat tataaccaat gataaagaaa
     5401 aactaaaact ttatgtctta gaaaccaatt tggacgatta catgatagac taagtaaaaa
     5461 gaaacaaaga ggtgtttaca atggggttga aatttgaacg tacagataat ttagataaac
     5521 ttttcgaatc atttgctgtc gatccggaaa aaacagttgc accaaaagaa gagatcgatc
     5581 gatttctaaa accacagcca caaaatgaaa agaaaaaaga caagaaacaa aagtaagtta
     5641 agctcaaaaa aagacttacc agccaaactt ttatgaaaga gtttgactgg taagtctttt
     5701 ttattctttt tatgattcaa ttgcttgttc gattgctgcc cacgcttctt cttttccctg
     5761 ttttgtaacg gaagaaaaga gaataaacgt gtcattgcga tcaaaatcca acgctttttt
     5821 gatttcgctc tcatgcttgt tccatttacc acgagggatc ttatctgcct tagtggcaac
     5881 aacaattaca gggatatcat aatacttcaa aaattgatac atctggatat cttcttgaga
     5941 aggcttatga cgcaaatcta ctaaagaaac gaccgcacgt agctggtctc tagtcgttaa
     6001 atatgtctcg atcatctttc cccattttgc tcgctcagtt ttggatactt ttgcataccc
     6061 atatcccgga acatcgacaa aatgtaatgc gttctcgatc aaataaaaat tcaatgtctg
     6121 ggtctttcct ggcttaccgg aagtacgggc taaattcttt cgatcaatca atgtgttgat
     6181 aaaagaagat ttccctacat ttgatcgtcc tgccagagct atttctggca attgtgtatc
     6241 tggatattgt tttggtgcca ctgcacttat gataatttca gcttgatgga ctttcatggt
     6301 ctctctcctt aacaaggtga tgaataaagc aagcggctgt cgcaaaagcc aaaatgactt
     6361 ttacggcagc ctcttttcat caacccgctt ttttctctga atctttatag attactgttg
     6421 gctcaccaga caattcagct gcttcttttg tgataatcac tttttcgatg ttttcatttg
     6481 aagggatatc aaacatcaca tccatcatga tttcttcaat gatggaacga agtcctcgag
     6541 caccggtatt gcgttcgatt gcttttttcg caatggctct caacgcttca ggttcgaatt
     6601 caagttcggt attatctaga gaaagaagtt tttgatattg tttgactagc gcatttttcg
     6661 gctcagtcaa gatccgtacc agatcatctg ttgtcaattt ctctaaagct gccataacag
     6721 gtaatcgtcc gataaactca gggatcaatc cgaattttag taaatcttca ggaatgatat
     6781 gctgcatgac actttcgtct tcagaaagtt tttggttttg tgtaccaaat ccaatcgtct
     6841 tttcgcccat acgattcttc acaatcgttt cgatgccatc aaatgcacca cctacgatga
     6901 acaatatgtt cgtcgtatca atctgaataa attcttgatg tggatgttta cgtccgccct
     6961 gaggtggcac acttgcaaca gttccttcta gaattttcag caaggcttgt tggacacctt
     7021 cgccggaaac gtcacgagta atagatacat tttcgctttt acgcgcaatt ttatcgatct
     7081 catcaatata gatgatccct ttttctgcaa gttccacatt gtaatcagca gattgaagca
     7141 atttaagcaa aatgttttct acatcttccc ccacataacc agcttctgtc aaacttgtcg
     7201 catctgcgat tgcaaaaggt acattcaatg tttttgctaa tgtttgtgct aaaaatgttt
     7261 taccagaccc tgtaggtccg atcaagcaga tattgctttt ttgcagttca acatcatctg
     7321 tgttttcttg tgcttgctga ttgacacgtt tatagtgatt gtatacggca acagctaacg
     7381 agcgttttgc gcgatcttgt ccaatcacgt agttattcaa tacttcaaga atttctagtg
     7441 gtttagggac ttcagtgaat tcgcgtacag cttcttcata aaattcttca tcaatgattt
     7501 ctttacatag gtcgatacat tcattacaga tgtagacccc tggaccagct acgatctttt
     7561 tcacttcttc ttgggttttc ccgcaaaaag aacagcgtac ggtctcattg ctacttggat
     7621 tgtcatacat ggtcttcacc ccttaacttg caaaaagtat gcaagaaact atcaaagact
     7681 ttacagtctt ttactatcat aacatagttt agtaaaaaga aaaagtgttt aacaaaggat
     7741 caactgacct atacctttgc attttttact cttaacaaaa aataaggaac tgtgacaaaa
     7801 tcgtgtcaca gtcccttatt tcgaataaac aattttctag aagtagcttc ttcagaaatg
     7861 atttattact tgatttctat tctttcgctt ctgtcgctgt acctgtgatc aattcgattg
     7921 cttttttcat tgtcacatca tgttccagca tatcttctgt caacacgcgt ttgatttgtt
     7981 cgattggcat gttgtatgtt tctgataatt cttggatttc tgcattgatt tcttcttctg
     8041 ttgcttgaag attttcagca gctgcaattg cttcgatcac aagatttgtt cttgtgcgca
     8101 tttctgcttc accttcgaat tgtttatgca agtcttcttc tgtagaacca gttaattgat
     8161 agtacatttc aggagagata ccttgacgtt gcatgttgtt caagaattcg tccattgaac
     8221 gatgtacttc atcatgaacc atcacgtgtg gcaattcaac gatttctgcg ttttcaacag
     8281 ccatacggat cgctgcttca tcttttgcat cgtccgctgc tttttctttt gtttctacta
     8341 attctttgcg atatttttct ttcaattcgt ctaatgttga tacttcgtca tcaacatctt
     8401 ttgcgaattc gtcatctaat tcaggcactt cttttgcttt tacttcatgg attgtcactt
     8461 tgaagactgc ttcttttcca gcaagatctt ctgcttgata atcttctggg aaagttacat
     8521 ttacatctag actttcacct gatttatgac caactaattg atcttcaaaa cctggaatga
     8581 atgagcctga acctaattca agtgagtaat tttcgccttt tccgccatca aacgcttcgc
     8641 catctacaaa gccttcgaag tcgattacta ctgtatcgcc attttcagct gcagcatctt
     8701 ctttgataac taattcagct tgtgcttctt gttcacgttt gatacgtgca tccacgtcag
     8761 catctgttac ttcacggtct tgtttttcaa caactagatc tttatattgt cctaatttta
     8821 cttctggttt cactgttact tcagcagtga ttacccagtc ttgacctttt tccatgcttt
     8881 caacatcgat ttttggttga gaaacaggat cgatgccagc ttctttgaca gcagcttcat
     8941 aagcttctgg taatacagca ttcaatgcat cttcatataa agcttcttca ccgtacatac
     9001 ggttgaatac ttgacgagaa actttccctt tacggaatcc aggtacgttc aagctttttt
     9061 tcactttatt aaacgcagtt gttaatcctt tttggatttc gtcttgcgca atcgtaaatt
     9121 ttaaaacacc atcattcgtg cctttttttt caaatgttgc agtcatttaa ttccctccga
     9181 gtttagaaat tcattttata catcaaaaac gtttcatgca tacctttaaa tagtacacta
     9241 accctttcaa attgtaaaca tattgaatgg atagaatcct tgtttttcat aacattttta
     9301 tctttttcac tgataaaatc taatggaaga agatcatttg ctgcaaaatt ttttctcttt
     9361 tttttaaaaa atcttgtttt tcatcttctg taccttcata catcgttttt cctgtacacg
     9421 cctctacagt cagttgaaac cagcgcttcg ggtcttcgat gtatgtatca tagacaggat
     9481 aaacaattgc agattgcaac gtgaattctt cttttaacac ggaactaagc agcgcatctt
     9541 cattcccgta acgatctgaa aatacacata attgctggta acttgcctgc tgctgcggct
     9601 ttggcagatc ttttggtatg actttgacta acttttcttc aatcgtcaaa tagaaaacag
     9661 gatggcattc gttcaattgc ctaagtgtct ccagtaattt tgcccttgct aaaatatgga
     9721 cctctggcga tacaataagt ttactcgctg tttggataaa ctcatgataa ggaagctgtt
     9781 cgatctcatc aatagacgca agctgacgtg caggttccaa cgaaggaagt tcctccgatt
     9841 tattgtggag tgccttgatc ttctgcctct ccatttgtcc ggataattct tctgcaaatt
     9901 ggattttttc aatgacccgc tgctcgaaag cttcataaaa atctgtactt gctatcaatt
     9961 ttctagcata taaaaaatct tgtgtactga ttaacaagtc aaaataaaat tcagcaaact
    10021 cctcattttg aagatactgt ttttcatgca agagtgcttg cttcaatgct tcttttttct
    10081 cgtccaactc gtaaagacaa aaaacaagca ggctattagc ctcaaagctt tctttcaact
    10141 cgtaagctcg ttgaaataat tcttttgcct gctgatattg ctggtttgct agtgcttgtt
    10201 gtgccactcg cattaaattc tcatattttt ctggaaaatc aatcggcttc acgcagtgtc
    10261 ctcctcttgc tcatattcag ctcatgttca atagtagcaa aacaaaaaaa gcatgacaat
    10321 taaaaataac tgaagcaccc tctaaaagct agattttaga tctgactttt agaaggtgct
    10381 ttcaactgtt actgcttttt attgctcatc agctgttgac ttcctggttg aacgctttga
    10441 tcagattgat cgtaacaaca cttgtattag tgaaaaaatc gcccagatgt tgctttttct
    10501 gattaaagac tgctggaaga taccctaaca tcagcaaagg aaattttaga atgaaccggc
    10561 aagcaccttc tctaactaaa acggttgacc agctaagttc ttcttcatca aagctgatga
    10621 ctcgaatacc aaagatcatt ttcccaatcg tttggccatg attgaatttc gtcaataaaa
    10681 taaaatacgc tagataaata agtaaggctg tgaatccgta gagactcaga taagaatctg
    10741 aaaaattaag ccaacctaga tttttggcaa taccaagtgt taaacgcgta atagctccga
    10801 tacacaaaag atcgaccaag aaggcaaaca ttcggataaa aaaacctgca tagaaatact
    10861 taggaaaatc atttgctttt ggcggttcat ttcttgtgtc cgtatacttt ttccatttac
    10921 gttgtttctt tttgatttct tcgggcgtca aaggctctct ttcaaaagag ctcagtacct
    10981 tttgggaaaa gttggagtca ggtcctacag caggctgctg ttgcttatct ttttcttgtt
    11041 ccttattttc atttgaaagc tctgacatgc ttactcacct ccgtaataat acattgcttt
    11101 tggtgattcc gctgtcccta gattctcaag aacggataag atctgactag tctcagaagg
    11161 cttcaatccc tggaattctg ctagtttact tcctaaccat gtactagcaa acccagatgg
    11221 cgtggaagaa tattctacta gttccgcatc ttcaagctgt tgttcctttc gtatagcttt
    11281 taaagcatct tcaggaaatc ccaattcatc gactaaacct acttcttttg cttggacacc
    11341 atcataaatc cttccatcag caattttttt gacttcttct tcagatttat tccgtccctc
    11401 gctgacgatt gctacaaaac gactatatgc gctgtcgata tatgcttgaa gcaccgcttc
    11461 ttcttctttt gtctctggtc gcgttcctga acccatatct ttcaacgctc cgcttttaac
    11521 tgttgtatct tccacaccca gtttttctag aagtcctgaa taattcaatc ctgacatgat
    11581 cacaccaatt gagccggtca ctgtttcttc tgttgcaaag attttatctg cttgagcaga
    11641 aatatagtag ccaccgctag ctgccatgtt tttcatgctg acatacattg ggatatcatg
    11701 ttctttacga atcgtatcca atttcttagc gatttccgca ctttcgtaga caccgccacc
    11761 aggagaattt acttctaaaa agataccttt gactgttgga tcttcttcaa tcgccttcag
    11821 ttgttccata aaatttttat gattgtaacc ttcagaagca aataaacctg aagaccctcc
    11881 cgcagcaatc gttccatcta ctgataattt tacgattttt tgcgtactgt ctccctcttc
    11941 caacacattt ggagctagtt cttcatcccc atataaccaa ctgttcaatc cctcaatttg
    12001 atcgttttcc tgaggcttag tcaaactagc tgaaactaac gaaaccacaa ataatcctgc
    12061 agcaatcaga actgctgccc aacgtctttt attcattctt tctcctttct aatacaagtt
    12121 ttttatgacg atcacagttt ctgactgctc agaagtgtcg aaccgctctg ctttttcttc
    12181 ccgcgcatac ccggaaaacg actcttttgt taattcatct tctaccgtaa actcacgagc
    12241 ttgagcaact tccaaggcat caggtgcgat ttcttggatg ctatcccagc cagtatctaa
    12301 aaatattttc gtatcatctg atacaccagc tgatgcttcg aatttggaca attgtttttt
    12361 taacattccc agtgtcatga tctcaatttt tgaatccatt tttactcctc ctctatccga
    12421 ttactttcta ttgtaccgaa ctcctgaaaa agatgataga taaaaaccca ttattttttg
    12481 acataaaaag gacatttgac aaagaatttg atatatacca atttattttt tattcttttt
    12541 ttgttgacaa gaacattcgc aaaaggttat gattttaaat gtttccagat aaaaaacaaa
    12601 aaggaggata gttatacctt ttaggatagc gccaggtctg tgtaaacaga tgacgaggag
    12661 agggtttatc gaaagattcg gcggatggcc ctagggactg cactctacag aaaatccaca
    12721 aaaaatgtct gcaaagataa aacaaaagga ttttcctgca gctggaagca ttcatacgaa
    12781 ttcattatag aaagtaggat gttttttatg tgcggaattg ttggaatgat tggattaaaa
    12841 aatgtaacac caggattgat tgacggtcta gaaaaattag aataccgtgg ttatgattca
    12901 gctggtatct ttgtctcaga tggcacaact gattatctgg tcaaagcaca aggcagaatt
    12961 caaaatttga aaaacaaaat aaatattgat actacaggaa atataggtat tggtcataca
    13021 cgatgggcaa ctcacgggca accttctgaa gaaaacgccc atccacatac ttcccaaagt
    13081 ggacgcttcg tgctcgttca caacggcgta atcgaaaact ttgaagaact taaaattgct
    13141 tatttagcaa atgaccactt tattggtgag accgatactg agattatcgc tcatctaatt
    13201 gaaactttcg cgaaggatac tacaacgcaa gaggcgtttt taaaagcttt gcgggtcatc
    13261 aaaggttctt acgctttcgc tttgattgat cggacagcac ctgatgttat ttacgtcgct
    13321 aaaaataaaa gtccactatt aatcggactc ggcgatggat tcaatgtgat tgccagcgat
    13381 gcaatggcta tgcttgctca tacgaaggaa ttcgttgaga ttgaagatga agagatggtt
    13441 accgtcacat cagaaaaagt tattattcaa aattttgcag gtgacatcgt agaacgttct
    13501 tcattcgaag cacaagtaga tgcttcagat atcgagaaag gtacctatcc tttttatatg
    13561 ctgaaagaaa tcgacgaaca gcctattatc atgcgtcgta tcgctcaaaa atacgtaaca
    13621 gaagacaatc gtgtctctct tgatcaaaag ctggtcgata cattgtctga tagcgatcga
    13681 atctatatcg ttgcttgcgg aactagttac catgcggggt tagcaggtaa acagactttg
    13741 gaaaaattga cacagattcc tgttgaggtt catttagcca gtgaatttgg ctataacaca
    13801 cctcttcttt caaaaaaacc attctttatt ttcttgagtc aaagtggcga aacagcagac
    13861 agccgccaag tgctggtaaa aatcaaccgt ctcggctacc cttcacttac gattacaaat
    13921 gttgctggtt ctactctttc gcgggaagca tcctttacac tgctattgca tgctggaccc
    13981 gaaatcgcag tagcatcaac gaaagcttat actgcacaaa tagctgtact aactttatta
    14041 gccaaagcta tcggtgataa aaaagaattt gaaacttctc ttgtattcga tatcactcat
    14101 gaattgagtt tagttgctaa tgcgatggaa tcggtcatcg cccaaaaaga ttatttagaa
    14161 gagttggcag aagtatatct cagcgataca agaaatgcct tttacattgg acgtggtgct
    14221 gactacaacg tttctcttga agctgctttg aaattgaaag aaatcagtta tatccaggca
    14281 gaaggttttg ccgctggcga attgaaacat ggaacgattg ctttgatcga agaaggaaca
    14341 ccagtgatcg gaatcatcag tgaagaagtg actggtgcgc atactcgagg aaacctgaaa
    14401 gaagtcgaaa gccgtggcgc taaaacacta gttattgtct cagagggatt agaaaaggaa
    14461 agtgaccagc tggtgctacc aactgtccac ccttatctaa ctactctaac cacagtcgta
    14521 ccgactcaat tacttgcata ttacgcaacg ctattacggg gattcgacgt tgacaaacca
    14581 cgtaatttag cgaaatcagt gacagtagaa taataaaaga acaaggacca gtgtcagaca
    14641 tctgacactg gtccttgttc ttttattttt tatgaaaata tctcttaatc cagtccgatt
    14701 tcttctttga ctactgccgc gattttatcg acatagtaat taactttctc atcagtaggc
    14761 gcttctgcca tcactcgaag taatggttct gtaccggaag gacgaactag gattcttcct
    14821 tctgatccca tttcagcttc tgcctcttca atcacttttt tgattgccgg aacatccatc
    14881 gcaccgtttt tatcacttac gcggatattc actaattttt gcggatagat tgttacctct
    14941 gctgcaagct ctgataattt cttacctgtc tgtttcatga tattcagtaa ctgaattcct
    15001 gaaagcatcc catctccagt tgtgttaaaa tctaagaaaa tcatgtgccc agactgctcg
    15061 ccgccaaagt tataatcgtt tttgcgcatt tcttctacaa cgtaacgatc accaacttgt
    15121 gtaacgacat ctttcaaacc gattccttcc accgctttgt ggaatcctaa gttactcatg
    15181 acagtcgtaa cgatcgtatc ttttttcaat cgattttttt ctgccaagta tttagcacag
    15241 ataaacatga ttttatcacc gtcgacaatg tttccaagtt catccaccgc aataatacga
    15301 tcgccatcgc catcgaaagc tagtccagca tctgctcctt tttcaacgac catctcagct
    15361 aaacgttctg gatgggtaga gcctacgccg tcattgatat ttaacccgtc tggatttgtg
    15421 cccattgtat aaaaatctgt ttcaagatcg gcaaacaaac gattaacact tgttgaagtt
    15481 gctccgtttg ctgcatcgac acaaatggtc aaaccggaaa ggtcaccgtt gatcgtttgt
    15541 acaaggaatt gagaatattt caataagcct tctggaaatt cttctacagt tcccaatcct
    15601 tcagctgatg gacgaggcaa ttcatccact tcagcatcta ataatgcttc aatttctagc
    15661 tcttggtcat ctactagttt aaaaccatct gcaccgaaaa atttgattcc attatcttgt
    15721 gctggattat gagaagcaga aatcatgacc cctgcgcttg ctttttgcaa acgtgtcaga
    15781 taagcaacac ctggtgtaga gatcacacct agctggaaca cttcgatacc caccgataaa
    15841 agtcctgaaa tcagcgcttc ttctaacatt tgacctgaga ttcttgtatc ccgccctact
    15901 aacacgcgtg ggcgttttcc ttcttcttca tgctggctta ggacataacc tccgcaccgt
    15961 cccagcttaa atgcaagttc tggcgtaagt tccttgttgg cttcaccgcg tacgccgtct
    16021 gttccaaaat atttacccat agttgtaaaa ttactccttt aacttaattt tctgaggaat
    16081 ttgttctgct catttgtgtt gattcgcttg tttctgatgt ttcttctgta cttgtggtcg
    16141 agctgcttgt cccagattcc gaactggaag aaatggttgt tgtcgatggt tccgttcctg
    16201 aatcagcaga tgaaatactt ctactcgtac ttgtattttc ttgtgtccga ctgctcgtcg
    16261 aagcagagct actgcttgac gtttgcaaca cgggtgtaat ctccacacta actgattcgg
    16321 gcttgatact taacccctct tctactggta tttcaatttt acgagttgtt cgatgattga
    16381 tacctgagac attgatcggt acagcaatac tgtcaccgat cgatgcaagc aaatcgctag
    16441 agccgcttac ttctgcttcc agttttgaaa aactgaaatc atagctttct accccggcag
    16501 ctggtgttcc ttgctgtatc ccataaagtc gtaccgactt gcttggcttg atcgaatcag
    16561 ctctcactgt tacttgcact ggatcagaga cgatacttaa tacttcccct gctgcattca
    16621 gcgcctgtat tgggacctca ctattaatcc catcatctgt gaccatcgaa gcgtccacat
    16681 cagctactac tcgtttgatt tctgccaatg ttttgtcacc tgtagtgatg gagacttttt
    16741 taggactaac ggaagtatca tcaagttcat atccagatgg tgtgaacgtt gaaggaatca
    16801 acgtttccac atcgaaatct tttattacct ttttctcaac cgttactgta atagtcgatg
    16861 gttcgatctt tgctgtgaca gcactgctca aattttgaat ttttagcgga acttcatgtg
    16921 ttccttcgcc cagcttagtg atatctgctg tgacgcggaa catccgtgta tcttcgtttg
    16981 cctctgcatt caactgaact cggtttgcac tggaaagttt gacagtcact gcattttcat
    17041 atccatggat atagtagcgc tttgaatcat aagaaatctt gatcggcacc cccgtaactg
    17101 tttgattata cgcttcattt ccagaaagcg tatttggaac ggactggcca tttgcattga
    17161 agtacagcgc aatactgaac agcaatgcaa taaaactgta aagaatgctt gtccgtttct
    17221 cttttgagat catttgcgat cccctccctt agtcataccg tctaggaaag attgaatcac
    17281 gtttttcttg ttttttgttt tctcttcagc aattagttct ctacgcaaga ttgccaaata
    17341 ttcttgctgg gataagccag ccatcagttc attatctaac gtgatgctga cgtccccggt
    17401 ttcttcagag acaacgatgg taatcgcgtc actgacttcg cttataccga cagctgcccg
    17461 gtgtcgagtc ccgaattctt tagggatcaa catactttct gatagaggaa gataggcgct
    17521 tgctactgcg atctttcctt cttttacaat aactgcaccg tcatgcagcg gtgtattagg
    17581 aataaagata ttgatcagca gctccccagt gatatctgca tctaaagcaa tccctgtctc
    17641 aatatactca tctaatccag tatgacgttc gatagtgatc aacgcaccga tttttcgctt
    17701 ggacatatat tggatggctt tgtcaaaaga caagatcatc ttctcatctt cctgctgttc
    17761 gctttttgat tgtttgaaaa gcgaactgcg tccaagatgt tccagtcctc tccggatttc
    17821 cggctgaaaa atcacgatag cagctatcac cccgtacgta atgacttggt tcatcagcca
    17881 agacaaggtg tgcagaccaa tgatttccgc tacgattcgg ataacaataa aaatagctac
    17941 acctttcaga agctgaatcg cttttgtgcc tcgcagcagt tggatcagtt tgtatacaag
    18001 ataccagaca accagaatat caagtatgtt caccaaaaaa ttcagagaga acaagtcacc
    18061 ggaaaacatt tgctgccaat agtccaaatt aaaaagttcc ccgatttgaa atgacataaa
    18121 aagcctctct tctcttttga gatttcctct ctagtatatc atatgtttta attttagagg
    18181 ctgatatgct cgtatttttc ttgagaaaaa cgcataattt tcaagaaaat tgcaagtatg
    18241 cgttttattt ttctctgcaa taaatatttt taaacttcag agaattattc attatatttt
    18301 ttctgttatt tttccttttt ttcttttgta gcttgttcca tttttttacg tcgttctgct
    18361 ctggcagctc ttctagcagc tcttctttct tctgcttcaa ggtccgtcgt tttttctttt
    18421 ctagtcttaa cgggtacatc gatagattcc tctggttcaa gtcgtttctt gattttttct
    18481 aattctcccg tcagtgcagc atagttgtaa aaacgtgttt tagcgtcgtg gacagtcttt
    18541 tcaaataaag cttttgcaag atttggattt gcgttatcta gcgaggaaaa gcgaacttgt
    18601 ttcctcatga aatcaggcat agcagagaaa tcaggttttt tgtagtccaa agtcattggg
    18661 ttcttgtttt tttcgaccat tgtagggtta tatcgatata atgaccaata accagaagaa
    18721 acagcttctt ttgcttcttt aagcgattct ttcattccgc caagcaagcc atgtgtgata
    18781 caaggcgtat aggcaataat cagagaagga ccaggatact tttctgcttc ttcaaatgcc
    18841 ttgatcgttt gcatttgatt ggcacctgaa gcaatttgcg ccacataaac atttccatat
    18901 gtcatcgcca tcattcctag atctttcttt gaagcatact ttccactagc cgaaaattta
    18961 gcgattgccg aagctggtgt tgcttttgag gtttgaccgc cagtattgga atagacttcg
    19021 ttatccaaaa caaggatatt cacgtctgct ccgctggcaa gtacatgatc gatcccgcca
    19081 aaaccaatgt cgtaagccca tccgtctcca ccaatcatcc attggctgtt ttttacgaat
    19141 agatcctttc tcttgtatat atcctccagt tcagggaaaa ttgatcgttc gctttcgatc
    19201 gcagcttgca gttttgctgc tctttgctgc gttccttcac tctcaaacat gtgtactaac
    19261 cagtcttcca tcaattctcg tagttcttct gatacttttg gcaatacttc tttgattgaa
    19321 cttgccaaag cctcgcgacg agtctgtgcc gctagaagca taccataacc aaattcagca
    19381 ttatcttcca ataaagaatt tgaccatgca ggcccttgac cacattcatt ggtcgtataa
    19441 ggagaagcag gagaagcacc gccccaaata gaagaacagc ctgtcgcatt cgcgatcatc
    19501 attcgatcac cgaacatttg tgtcaataat tttacataag gtgtttcgcc acagcctgag
    19561 caagcgcccg agaattcaag aagcggttga ttgaattgtg tagacaagac agtattcttt
    19621 cctttgactg gatttgcttt ttgtcttaat gtcattgcaa aagcccaatt cacagcttgt
    19681 tctttctgtt cttcataagg cttcatcact aaagcttttt cttttgcggg acaagcctct
    19741 acacacagac cacaacctgt acagtcttcc actgaaactt ggatacggta ttttacgccg
    19801 tctgcgcctc gcatttctct cacgataaat ccttctggcg cttcttccat ttcctcttca
    19861 tctgctaaaa atggacggat ggcagcatga ggacaaacaa aggcacattc attacacatc
    19921 gtacagcgat cactaatcca ctcaggtact tctaaagcga cgccccgctt ttccatagaa
    19981 gccgttccta aaggcatttc gccagttgtc attccatttg ctacaagtgt accaacagag
    20041 agttgatttc cttcctgtgc attcactggt tcaagtattt cttgtatata accagtgttc
    20101 cttttattga ttttttcagg catctccaac gttctccaat ggtctgggat cgcgacttga
    20161 tgaagcagtt cggtcgtccg atcgattgct tgtatgtttt tttctacgat agccattgat
    20221 ttatgtccat agcttttcag ggcttcttct tttagcagcg gaagcacctc atcaaaagga
    20281 atgatgtcag ctaatttaaa aaaagccgtt tccattgccg tattgatccg gcgtcccaaa
    20341 ccgacttctt gggccaatct catggcattg atcgtataga atctaatgtt attttcagcc
    20401 aagtaacgtt ttaattttaa gggcagatgc gtttctaatt gttcgtcgct ccaaagagta
    20461 ttcaataaaa aaatgccacc tggcttcaat cctttgacca agtcatagct atgcaggtaa
    20521 gctggtgtgt gacaggcaac aaggtccgca tgctcgacaa gatacgctga acgtatcggc
    20581 gtatctccaa aacgaagatg agagacagtc agaccgccag attttttcga atcataataa
    20641 aaatagcctt gcgcatattt atcggtgtga tctccaataa tcttgatagc tgatttattt
    20701 gctccaactg ttccgtcaga tccaaatccc caaaacttgg cctggaatgt ttgcggttct
    20761 gtcaaatcca gactttcctt tggttccaaa gattgataag tcacatcatc cacgatccct
    20821 atggtaaacc gttttttgcg tatgcttggg tcttttttca attcatcaaa aactgctgag
    20881 atttggtcgg gagtcacatc tttagacccc aatccgtagc gaccaccaat aacagccggg
    20941 cgaagttcag aatcatataa cgcactttga acgtctaata agagaggttc tccacctgcc
    21001 cctggttctt tacttcgatc aagaacagca attgttttta ctgtatgagg caacttttgc
    21061 acgaatgttt ccactggaaa aggacgataa agatggatat tcaaaaaacc tgttttccgt
    21121 ccgtttgcat tcaagtaatc aatcgtttgt tcaatcgtct gtgcaactga tcccatagaa
    21181 acaatgactt cttccgcatc gtctgctccg taataagtca ccaagtcata agaagttcct
    21241 cgtaatcggt tgatctcttt catatatttt tgaacgattt caggtaattt atcataatag
    21301 gggttgatcg tttcccgttg ttgaaaatgg atgtctggat tctggttcgt accactaaca
    21361 gtcggatgat tgggattcat ccctcgttta cgaaatgaag ctaatttctc ctgattgatc
    21421 agaggagcta attcttcata ttccaaaact tcgatttttt gaatctcgtg actcgtacgg
    21481 aatccatcaa agaaattcaa aaaagggact tctccttcaa tagaagcaag atgggcaaca
    21541 ggtgctaaat ccatcacttc ttgtacactg ctttcagcta acatagcaaa tcctgtttgt
    21601 cttgcagcca tcacgtctcc gtgatctccg aaaatattca acgcatttgt cgtcactgcc
    21661 cgactagcaa cgtggaaaac acttggcagt agttccccag caatcttgta catattcggt
    21721 atcatcaaaa gcagcccttg tgaagcggta tatgtagttg tcagtgcacc agttttcaat
    21781 gatccatgga ccacaccagc tgctcctgct tcggattgca tttctactac ttttactggt
    21841 tgaccgaata cgttttcttt tcctgctgct gaccattgat ctactaattc agccatggtc
    21901 gaactgggtg ttattggata tattgcagca atctcggtaa atgcataaga aatatatgcg
    21961 gctgccgtat tgccatccat tgttttcatt tttcgcatga ttcatcatcc ttgttcatat
    22021 tctctcttat tatctgttcc attataacgt aaaacatgcc atttttttct tttatttata
    22081 aaaatatttt acatgtatct atttgaattg gtcatctaat ttttagacaa acagtctaaa
    22141 tcgttgcctt tttttgtcag acatgtataa actataagcg aaagaggtgt tttaacatgg
    22201 atatatcagt gattgatgca acgaaaacaa atacacaaaa aggaatcctt tatggttcat
    22261 cgaatgctcc taaaaaaatg gtcgaattca tcaacttagc ttgtccgtat tgccgacaat
    22321 ggtttgaaga atcttatgag ctattagaag aagcagtcca aagcgggcaa ttgcagcgag
    22381 tgatcaaatt gttcgataaa gaaaaagaaa gcttacagcg agggaacgtg atgcaccggt
    22441 atctcacaat cagcgatggc caaaaagcga tcaaagagat caaacaaata ttcgatactc
    22501 aagacgagtg gaaacatctt tctctccaag aagtagcgga ttttgcagta gataaactaa
    22561 agctgacaga acaaaaagac gaacagctga gccaagctgt catcaacgaa gctgagcaag
    22621 cacatattcg atttgttcca actgtcatct tgggtaaaga aatctttgat gaatctattt
    22681 caatagagga attaaaagaa ttgatccaaa caaaataaaa aaataaggag cgtgggacaa
    22741 aagtaaagaa cacttttgtc tcacgctcta aacacgtata aacggcggaa gcagaagcaa
    22801 ctccttctta tttcttggag ttaaacgctt ctgtcccagc ctccttattc cgaataaatg
    22861 gtgtccaaaa gcttgcatct gccagattat ctcatttctt atgacaagct aagcaaatta
    22921 tctccaccaa ataatttatt catatttttg acttgcgcat actaactaat tcttaaattt
    22981 tcatacaaaa tttctcaatt tcccttaacg agtaatattt atgtacggtg attctcacta
    23041 gtatcccaat cactttttaa gttatcccga tttcaattct acttcaaaaa tagttgcttt
    23101 tatgtatgct gttagttgat tagatggtca tttgttgagc taggtcgttt attttaaaca
    23161 agttgtttct ttagcttata cctatctcgt ctaccaaacg caagatggca aacacaaatg
    23221 catacgcatc tgtatttgcc actttgattc gtataaagct aacaactatt aactcctctc
    23281 agctaatagt tgctctcttt tttattcaga ttcatttttg ctgatcacag cctagtattt
    23341 caatggtttt gaacactaaa ccaaattgtt ccattacaac attcactggc tgatgaaatg
    23401 gattagtaga tttcgattat tcaaagcgat tttctattgg tggatcgtgt tcccaactaa
    23461 taagacggat tccaaaccta tcgtacagat cttctaaacc acttataaat tttgcaccta
    23521 tttcaggtgt tttattgcgt ggatattcta ttgttacgcc attaaatgga taccaattag
    23581 gattaggctc tctttttttc tgtacatctc ccatagaata gttagcactt tctgggacat
    23641 aatatattct tcgaccatcc tctaattcat ctaataagat atttcgtgat cgtctatcac
    23701 ttgctaaatg tagacgccac gtgcgatacc atgccatgct acctgcatct gcagaaaatc
    23761 catcaaataa tgcaacaatt gtatcttcta tcacaatcct ttccccatct acttcatatt
    23821 ctaatctaaa atcaaactcc cctcgggtaa tttctggtct tggtggctta ggacccaata
    23881 ttattctact taaaaccgca ttcgttccca gatgaaacac agctataaca acaataatga
    23941 ttaatatttt gtttctattt gataaatttc tcattattcg cacatcacct ctacattctc
    24001 acatattagt tcgtaatact cctttaatat caaaatatct actggtcgta ataatattcg
    24061 ctatgaattc ctactactcg tataagaaag gccaaatcat cagcttttac ttgctgatga
    24121 tttggcttgt ttctatttat cgtaattgtt ttctaatcac caaaattgtt aacaatcggt
    24181 tcagatattt cccagttgat taaggtaatt ccgtattgtg tcaaaacttc ttgcgcttct
    24241 ccgaaattaa gtacagttct tatgtatcca ctttctccta atataaagtc tacctctctt
    24301 ttaaaacctt cctcgagatt tctaagggct atatgtggtt ttaatgacat tgattgtaca
    24361 ttttccccca tataatattg cgcacttcct cgactaaaat agattcctag atcgtcccca
    24421 aaaggtagat cttctctacc actagctaat ctacttctcc atcttcgttc tcttttcata
    24481 gaacctgcgc tgaactcaca cccgttaaac tcagctatga cagtatcttc aattatgtta
    24541 atctgtccat ctagttcgta ttcaatccta aatggaaatt ctccataggt gatttccggt
    24601 tcgggtattt taggtgagat taatgcaaag aaaggaaata ttaagcttgg caacatcaaa
    24661 aaaactcctc ctatgatcac aattcccgat gtaatccaaa atataatttg tacaattctc
    24721 attgatccat tgtattccat tttattcccc ctattactat tcatatccgc ctatctatat
    24781 cgatcttcca atgcagagat aattgcttcc ataccttgat tttttactga gttacctatg
    24841 cgagatatca ttctccacta aggtgcatca tattgtctat ctaacatgat taattctcca
    24901 ataggtgtat actcctccaa aaacaacatt taatgcatct ccctcgacaa cataagctac
    24961 catgtttgct gtatatgtgt ttgagtctaa ttcataagca gataaattta ctgtcgctgg
    25021 attaaatata atcgcattcg tatttatagc tactgaattt gctgcttcag caccaccttt
    25081 tgaatgtccg atcattgtga tttcaatagt aggatttacg tggacagccc tcaccgttta
    25141 ccctgaccat tatagaaatc gcttactttt ttgaactacg caacaaagga tacaatgctc
    25201 ctaacttcac tgtctccatt tttgtccact aaggaatata aaaaataggc attaattcat
    25261 ttaattcggt cacaacacgt taccttttaa atcattatac tgtatctcat acattattat
    25321 caataaacta ttataaaaat gcaaaaaatg ctttatcaat ctattttgta attggtcata
    25381 atatcattga aatcataccc tgtatcgatt tttcctatga atctcgtcta tttgtgattg
    25441 acgaaaaaga ggcaagacag acactggaat ggtaatttta cccactattt tgctccaact
    25501 atttgtaatc gtacccactt ttgaaatacc gagatgatca ttttaattga tatgctgatt
    25561 cccaagcaaa accccaagaa attaaatgct ctatcgcatc tagcttcttg ggttttgctt
    25621 atataaattc caacatttaa attttttatg ctgttcggtc tcagaaatgc cgtttttgct
    25681 tatatcacaa tatcaagatg tcaaattatt cgtgttgccg atgactttga ttaatttttt
    25741 tcaaattgtt tattaagact aatgctgtct ttttgcagat accaatgttc gaacttttta
    25801 acattatcat atgatcctgc aagttttaac ttcttaccat tagatgttat caaagttata
    25861 attaaccttg cctttttccc attaggatct tttattttat gaattttctg caggtaatct
    25921 ctcctaatgg cagctatttt tacctcatca gtgctgataa accattgatc atccacatac
    25981 atactgcctg ttatgttgtg tttttccatt tcttccgaga acgaaaagtt taaggctcgt
    26041 tcttacttcc aaagttgaat gagtccatgg attggactta gtgtgagaat tgagaacaac
    26101 aataagaatc catatcctcc cgcaaacatc cctaaggcta tactgtctct ccatccataa
    26161 gtaggattag aagagaaaag agtcaccgtt tgtaataata tgaaaaggaa taatccagca
    26221 caaacaccaa agataacaac tccaaacatt gaatttttat acaatgacca tttatttata
    26281 ggcttttctt tcattttact tccccctact gttctgttca cacggaatga attcaaagtt
    26341 cataagccct cctctttgaa catatgaata cgacttgcta actatacttt aaaaaagctt
    26401 gttttaagcg gttataggcg agttgtaatc tctattcatc tcattagcaa ataacttgcc
    26461 gaaaagtcta ctgaaattaa agcagatagt ggaagaatta tttagccagg atagacacta
    26521 tttgtgaaac acatgtcttt acttttgaaa ttctatgatg aaaagccttg gaatacagta
    26581 gctcttaatt ggtaatactt tttccattat aaataacctc ttttcatttt atatttatcc
    26641 cctctaaaaa taatatctaa tctaatattt taaacttata tttccctcgc tgtgctaata
    26701 gagcattact aaataaatag aaactagaaa aaagcattac gcctgccaga ataaaccaat
    26761 tatttgta
//
LOCUS       DACCVZ010000034        26160 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.034, whole genome shotgun sequence.
ACCESSION   DACCVZ010000034 DACCVZ010000000
VERSION     DACCVZ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.034"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(62..1093)
                     /gene="queA"
                     /locus_tag="IVW63_001450"
     CDS             complement(62..1093)
                     /gene="queA"
                     /locus_tag="IVW63_001450"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAP7859730.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1286..2461
                     /locus_tag="IVW63_001451"
     CDS             1286..2461
                     /locus_tag="IVW63_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP7859731.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2465..3106
                     /locus_tag="IVW63_001452"
     CDS             2465..3106
                     /locus_tag="IVW63_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7859732.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3103..4020
                     /locus_tag="IVW63_001453"
     CDS             3103..4020
                     /locus_tag="IVW63_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7859733.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4017..4688
                     /locus_tag="IVW63_001454"
     CDS             4017..4688
                     /locus_tag="IVW63_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7859734.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5229..5717)
                     /locus_tag="IVW63_001455"
     CDS             complement(5229..5717)
                     /locus_tag="IVW63_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAP7859735.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5918..6184)
                     /locus_tag="IVW63_001456"
     CDS             complement(5918..6184)
                     /locus_tag="IVW63_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAP7859736.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6184..6447)
                     /locus_tag="IVW63_001457"
     CDS             complement(6184..6447)
                     /locus_tag="IVW63_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP7859737.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            complement(6440..6712)
                     /locus_tag="IVW63_001458"
     CDS             complement(6440..6712)
                     /locus_tag="IVW63_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859738.1"
                     /translation="MYWCCCIDSQALDSTFAKDDTLLPITLRLATASRKGVRSERGQR
                     SSLKRGLFLYVKKRKSLLNLSALLYFFDVLNQVRYNYIRKRRRDNG"
     gene            6923..7108
                     /locus_tag="IVW63_001459"
     CDS             6923..7108
                     /locus_tag="IVW63_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7859739.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(7250..9073)
                     /locus_tag="IVW63_001460"
     CDS             complement(7250..9073)
                     /locus_tag="IVW63_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HAP7859740.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9671..12376)
                     /locus_tag="IVW63_001461"
     CDS             complement(9671..12376)
                     /locus_tag="IVW63_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAP7859741.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12682..13629)
                     /locus_tag="IVW63_001462"
     CDS             complement(12682..13629)
                     /locus_tag="IVW63_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HAP7859742.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13819..14088
                     /gene="rpsN"
                     /locus_tag="IVW63_001463"
     CDS             13819..14088
                     /gene="rpsN"
                     /locus_tag="IVW63_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAP7859743.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14264..14626)
                     /locus_tag="IVW63_001464"
     CDS             complement(14264..14626)
                     /locus_tag="IVW63_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP7859744.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14637..15758)
                     /locus_tag="IVW63_001465"
     CDS             complement(14637..15758)
                     /locus_tag="IVW63_001465"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAP7859745.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15774..16124)
                     /locus_tag="IVW63_001466"
     CDS             complement(15774..16124)
                     /locus_tag="IVW63_001466"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAP7859746.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16254..17765)
                     /locus_tag="IVW63_001467"
     CDS             complement(16254..17765)
                     /locus_tag="IVW63_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP7859747.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18087..19439)
                     /locus_tag="IVW63_001468"
     CDS             complement(18087..19439)
                     /locus_tag="IVW63_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAP7859748.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19592..20668)
                     /locus_tag="IVW63_001469"
     CDS             complement(19592..20668)
                     /locus_tag="IVW63_001469"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAP7859749.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20864..22609
                     /locus_tag="IVW63_001470"
     CDS             20864..22609
                     /locus_tag="IVW63_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAP7859750.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22889..23326)
                     /locus_tag="IVW63_001471"
     CDS             complement(22889..23326)
                     /locus_tag="IVW63_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAP7859751.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23310..24683)
                     /locus_tag="IVW63_001472"
     CDS             complement(23310..24683)
                     /locus_tag="IVW63_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859752.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(25005..25493)
                     /locus_tag="IVW63_001473"
     CDS             complement(25005..25493)
                     /locus_tag="IVW63_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7859753.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25515..26117)
                     /locus_tag="IVW63_001474"
     CDS             complement(25515..26117)
                     /locus_tag="IVW63_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP7859754.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7503 a         5561 c         4838 g         8258 t
ORIGIN      
        1 ctttgtcata aaatctttgt aaagcttttt tgttattcaa aactagcggc ttttcataac
       61 cttatttcac gaacatcgca tctccaaaac taaagaaacg atagcgctct tcaatcgcat
      121 gctggtaagc agataaagtc aattctcttc ctgcaaaggc actaactaac atgactaaag
      181 tcgattttgg caaatggaaa ttagttgaga aagcttctac cactttgaat tcatagccag
      241 gcgtaatgaa aatatcagtc catccgctgt ctgctttgat ttctccatta aatttcgttc
      301 caatcgtttc taatgttcga attgaagttg ttccgacagc cacgattttc ccgccatttt
      361 tacgtacttg gttcaatcgc tcagccgctt cttccgtcaa acggtagaat tcactatgca
      421 tatggtgttc ttcaatttta tctacgctga caggtcggaa tgtacctaac cctacatgta
      481 gtgtcagata gactaattca acaccctttg cttcgatctc atcaagtaat tctttcgtaa
      541 aatgcaatcc agctgttggc gctgcagcag aaccattttc tttcgcatag acagtttgat
      601 agcgatctgg gtcttccaga cgttctttga tatatggagg caatggcatt tctcccaatg
      661 attcaagaat ctctagaaaa attccttcat actcaaagtc aatgatccgt ccgccgtgtt
      721 ccaattcttc tttcactact gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa
      781 ctttggcacg tttcgcaggt ttgatcaatg tctcccacgt atctccttgt gtattcgtta
      841 gaagaaggac ttctaaatgc gcaccagtat ctggtttttc tccatataaa cgagcaggca
      901 gaactcgtgt attattcata actagcgcat caccaggctg taactcttca atgatttcat
      961 ggaaatgttt atcttccatc tctccagttt tccgatccaa aacaagtaaa cgagaatgat
     1021 cgcggtcttt taatggtgtt tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt
     1081 ctgttgttaa catatcgtca ctcactttct atcatgtgct tcatcattct atcatgtttt
     1141 tcgttctgtt ggcaaaatca gcactttttc acttctattt tttgttttcc taaataaaaa
     1201 aactacccta tttgtatttt ttcattgttt taggcatact agtaatagat agttcttcat
     1261 tgaaaataga aaaagaggtg gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa
     1321 aggtggaaaa gtcgctgtag aggacgtcaa tctttcattt gaaaagggtg agttcatttg
     1381 ttttatcggt acgagcggaa gcggaaaaac gacgacgatg cggatgatca accgaatgac
     1441 tgatccaaca caagggaaaa ttttgattga tggaaaatcc atccaagaaa ttgatccagt
     1501 ggaattgcga cgtcagatcg gctatgttat ccaaagtatt ggattgatgc ctcacatgac
     1561 gatccgtgaa aatatcactc ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa
     1621 taaaacagct gaaaaaatga ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta
     1681 cccacatgaa ttatctggtg gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc
     1741 gaatcaagat atcatcttga tggacgagcc attcggtgcg cttgatccaa tcactcgtga
     1801 ttccttgcaa gaccttgtca aagatttaca agagcgtttg ggaaaaacga tcgtatttgt
     1861 aacccatgac atggatgaag cgattaaact agcaagccgt atcgccatca tgagtgaagg
     1921 ccgtgtgatc caatttgata caccagaaaa tattttacgt catcctgcaa acgatttcgt
     1981 agaagagttg attggagaag atcgcctact acaagccaag ccaaatgcga caagagtcgg
     2041 cgaagttatg ctaaatacag caatcacgat tacaccggaa aaatcattac aagaagcaat
     2101 caaactgatg agggaaaaac gtgtagatac gttgttagtt accgataatt cgaatgtatt
     2161 aaaaggattt atcgatgtag aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg
     2221 cgacattttg aataaacatg ttttttacgt aaaagaatcc gcctatcttc gtgatacctt
     2281 gcaacgcatt ttaaaacgcg ggctgaaata cgtgccggtc gttgatgaac agaacaaagt
     2341 cgtaggtatc ctgactcgtg catcattagt ggatatcgtc tacgatgtga tttggggaga
     2401 agatcccgca actactgatg ttgcagagtc agctactcct gaagaatcta aggaggtctg
     2461 acctatgcag cagttttttc atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca
     2521 tctttatatt tcaggacttg ctttgatcat tggtatcatc attgctgtac cgcttggtgt
     2581 cttactgaca cgttttccaa aagctgccac gattgtgatt ggcttaacca gtgccttgca
     2641 gacaatccct tctcttgctt tattggcatt gatgatcccg ctatttggcg taggtaaatt
     2701 acctgcgatt atcgcactct ttatttattc attattgccg attttacgta atacgtacat
     2761 tgggatgaaa aatgtcgatt ggaattatcg ggatgtggca aaaggcatgg ggatgactga
     2821 gttccaatcc attttttccg ttgaattgcc cattgctatg ccaacgatca tggctggtat
     2881 tcgtttagct gccgtttacg tgattgcatg ggctacactt gcctcttata tcggcgctgg
     2941 tggtttaggc gatttgattt ttagtggact gaataattac caaccagatc tcattttggc
     3001 aggtacgatc cctgtaacaa ttttagcact attggctgat tggcttctag gtctcttgga
     3061 acaccggctg acaccgatcg cacttagaga ggagaatgaa gaatgaaacg tatactaaaa
     3121 atgaccatgg ttcttttctc tcttcttata cttgcgagtt gttccttccc tggtcttgcc
     3181 agcaatacag atgaagacac catttcgatc acaggtggaa tcacttcaga agcacagatc
     3241 ttagcaagtc tagttgccgg aatggttgaa cattatacag ataaaaatac cgcaatcatc
     3301 aacaatctgg ctactacaac tatcaaccat caagcgatga tgaacggaga tgcttcaatt
     3361 tcagcggctc gctacacagg aacagattta acgactacat tgaaccttcc tcctgaaaaa
     3421 gatccgaaaa aagcgtttgc taccgtgaaa gatgaatttg agaaaagata cggtcaaacg
     3481 tggttcccgt cctatggttt tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca
     3541 caaaaatacc atctatctaa agtcagcgat ctgaaaaatg tagcggatga attagtagct
     3601 ggtgtagata cttcttggat caatcgtaaa ggagacggtt atgacggctt ccaagaaact
     3661 tatggcttct ccttcaattc gatattacct atgcagattg gacttgttta tgacgcagtc
     3721 gaagcaggaa aaatggatat tgttcttggc tactctacgg atggacggat cgccagttat
     3781 gatctagtca tgttggaaga tgatcgtcaa ttcttcccac catatgatgc tgctccagtt
     3841 gtagacaaca agatattagc tgatacgcct catttaaaag aagccttaaa taagttaggt
     3901 cataccatca gtacggaaaa aatgcaggaa ttgaactacg aagcagataa taatctagtg
     3961 gaaccatcag tagtagcaca acgtttctta caagaaaacc actattttga agggaagtga
     4021 agcaattgga taaaatgaat gtctttcaac aatttttcta ttatttccag gaaaatggct
     4081 cctatatctt tgcacaattt atccgtcact tcctgatttc tatctatggt gtcctctttg
     4141 cagcagttgt cgggattccg gttgggatca tgatttctag gagacgtaaa ttagcaaact
     4201 gggtgattcg tttggcgaat atcatccaga cgatcccttc tctagccatg atctccattt
     4261 taatcattgg attaggcctg ggagtcaatg tcgtgattgt tactgtattt ttgtattccc
     4321 tcttaccgat catcaagaat acgtataccg ggatgatcca agtagacaaa aacatccttg
     4381 atgtcggcaa aggcatgggg atgactgcta gacaacgact attcatggta gagttaccac
     4441 tctctgtttc tgttatcatg gcaggcataa gaaacgcgtt agttgttgcc atcgggataa
     4501 ccgcgatcgg tgcattcgtc ggtgctggtg gtcttggaga tatcattatc cgaggaacca
     4561 atgcaacaga gggcacatcg attattttag caggtgcatt gccaactgca ttaatggcga
     4621 tcatcacgga ctggctttta ggtattttgg aaagacggct agatccagcc agccgtacat
     4681 cacgctgatg ttattgtaaa aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct
     4741 tttttagttc tgtcattttt aaggcaataa tccactctga ttcttccctc cttatgggca
     4801 aagagttgct tttcttagct atttatccat tccgtatact ccaacttcat actgccaacg
     4861 ggttcatatc tgcatccacc gactaagttt ttttcttatc cgctaaggca ttttgccaat
     4921 ccattttccc atcactcgtc atggaattca taccacatga tctctaaata ctcgtctgct
     4981 tgttctttga attgggcatc aattcttaca tcctttggcg tggctttcat ttaagccttt
     5041 tccatcagtc ctcgattgtt cgatgccttc agctgcatca tcaaaactgg tgactgccgt
     5101 atcggtaact tcgatcatct tttatacaat cgggaacttg ccatcctcat ccttggctaa
     5161 aaacatatct agccattcca gcttctcgcc atgggaggtt tgcggttcct aaaaccggta
     5221 cacgattctt atggactgca tccgtcgcaa ctagacttgg cgatacgatg atccttcacc
     5281 agaagagcac ccccgtaaac caattgatcg atatattgcc aataagaaaa gacattggcg
     5341 taaaagatat cgatccctcg tgatgcattg ccgttgatac tgctattcat ggccgaaagc
     5401 gccacgactt taacttcttc cgtttgagtg acattcatgt tcggcaatgt cgctttggat
     5461 acccgctctg ctaaaggaac gacactggta ttgtatttcg tatctgtatc ttttccaaaa
     5521 gaccatgcca acgaatcctc tgggaaccaa taagacgact ccggttgatt gtccattgct
     5581 tttttcaaca tacttttggc tgtttctcga taaacgacat ttccaattgt cttcgcctca
     5641 ctttggcgat aatcgatggt cgttgccact gccaacacta acaacgatgc tccaatttta
     5701 ctgattttcc ttgtcacact tcttcctcct tgttttacat aaacccgtca acattccatt
     5761 cctaaactca aacaatgacc cttcaaaggt ggagatatag gaacaaatta aagaaatcat
     5821 gcaataaatc caagaaggtt ggttttagaa caaaaaaaga gtctcctttt tggggagact
     5881 ctttgttaac tatctaaaaa ggttggctct tctcacttca ctcataatgt gtccaggcag
     5941 aataaatttc tacaacttta ttttcctcat caactttgta aaccactcga tgctgtctat
     6001 tcagcctgcg tgagtatctg ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg
     6061 gcatatatgg atcttccttc aatgtctgaa tcacttcttc aaattgtttc tttaaattcg
     6121 tttgcttgat ttttcttaaa tccactttcg cagagttttt gattgcgact gtatagttac
     6181 tcatcaaaga gcttcccaat caatatcatc gatattcgta aagctactgt cgtctttttc
     6241 gcggtctcgt actttatcta aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc
     6301 tctccagtct tccagcccaa tcaatacagc attgtttcca ctacgatcac taataatctc
     6361 gatttcagta tgattttcat ttacctcttt caataactga taaaaatttt tacgagcagt
     6421 gctaggattc atcgttgtat tagccattgt ctctcctcct ttttctgata taattatagc
     6481 gtacttgatt aagtacgtca aaaaaataca ataaagcact taaattcagc aaacttttcc
     6541 tcttttttac atagagaaaa agaccccttt ttagggagga tctttgtcca cgctcacttc
     6601 ttactccttt acgactagcg gtagccaaac gtaaagtaat tggtaacaac gtatcatctt
     6661 tagcaaaggt cgaatccaaa gcctgtgagt ctatgcaaca acaccaatac acgaaggttc
     6721 ctcgttgcag tgtgacttga ttgatatctt gaataacctg aggatacgca cgaaagattt
     6781 gtaacggtta ttcaaaactg attttggccg tcaagtcttc tactgcctca aaaatgattg
     6841 cctctttcgt ctcctgtcat tcatgttcac tatcgatttg atacttgctt agaccgttgg
     6901 gtttgtgaat caccaattaa aaatggcact gagttatggt aacaaaaaat ggtcacttga
     6961 cgaggctgag attcctactt atgaagacac atggcactta agagtcgagg taaaggaaga
     7021 agctgaaaat ataggaggct gtacattatt tggcaaagga ttcggaaatt atgatcaaga
     7081 catcaaaatc aaaatgtttt acagctaaat aggaagaata ataacatttc atacgctgtt
     7141 cccatcttta atggcttata gagggcacct ttagctgaga ataagacaaa acagaccctc
     7201 tagcttcaat taagagctag agggtctgtt tttgatttta aaacttggtt tatttcttca
     7261 aatggtagct ataggtgctg acaacgatat tttcacgcca agacaatcgc aatcttaacc
     7321 gcaaacttgt ttggttatgg agaatattct gccagcgtct gtttggtaca aattgaggaa
     7381 tcaacacagt agttgtatag ttttgtttcg ctgcattttt acttacgata tctacataac
     7441 ggataattgg attttcaatc gagcgataag aagagtggac gattgaaaaa cggacatctg
     7501 ggaaatgctt tttaaattct gcttcgattt ctttttcttt ttcgacatct tcgtctagcg
     7561 aaacatgcat cgcaacgaca taatcaccga tcgaacgtgc gtaattcaac gcaccgatat
     7621 ttacccgtgt cacattcccg actaatacaa gaacggtatt cccgtcataa tcatgtagtt
     7681 ttgcatcatt ttctaaacga agctgttctg ctactttttt ataatgatca tggatcttat
     7741 aaaaaatgaa cataacgatt ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat
     7801 agacaaacaa aatcgcaatg attgcatatg agatgaacgc acccgtaata ttggcaatcg
     7861 atttgcttaa ccatcttttt ccttcttttt tccatttgac gaccatccct gtttgagata
     7921 aagcaaatgg aatgaacacg ccgatagagt ataacggaat caagcgttct gttgagccat
     7981 ggaaaataaa cagcaatacg atcgaaccta gcgctagtgt gataatccca ttggaatagc
     8041 ctagtcgatc cccacgatct tgatacatgt gaggcatgaa tttatctttt gccagattgt
     8101 atgcaagaac tggaaaagca gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg
     8161 tagcaaattg aaggacgtaa tacaaaatac catgtccaaa gacagcttta ccaatttgag
     8221 acaaaacagt gacttctttt tcaggaacga tcccatacca atagttgata aatgtgatcc
     8281 ccacgaagaa gaaacctaag atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg
     8341 ctcttggctt cttaaagaat ggtacagcat tactaatcgc ctccacccca gttaaagagg
     8401 aagaaccaga agaaaatgct cgtaaaatca aagcgataga aacacccggc acagccgctc
     8461 ctggaagtgc agtagcttgc aatggcacag cacctgtcac gatattatat aaaccaacaa
     8521 cgatcagtaa cgagatcaca aggataaatg tgtacaccgg aaataatagg aacgatgcag
     8581 attccctcag cccacgaaga ttcagcatca tcagtagcaa aacgattgtc acagaaatag
     8641 cgacttgatg accgtagagt gctggcaccg ctgatgtgat cgcttcagca cctgctgaga
     8701 cagatactgc tactgtcaac atgtagtcga tcaataaaga gccaccggaa atcaagccag
     8761 cattctttcc aagattctca ctgctgacga catatgctcc cccgccatga ggataagcat
     8821 ggatgatttg acgatatgat agcgttaatg aaatcaataa aataataaca aaagcggcaa
     8881 tgggtagcga ataccagatg gctgcagcag acaaagcgac taaaacgaca acgatttgtt
     8941 ccgtaccata tgcaatagat gataacgcat cagacgacaa taatgccaaa gcagcaaatc
     9001 gggttaattt gtgctcatca ttttcagcag attttaaagg cttacctact aacaaccttt
     9061 ttaagtaatc caatttctaa actcctttac acacaatttt acttcaagtt ttatagtcga
     9121 aaatttatag taaacaagat gttatagtac gctcactgac cttaaaagtc aataaacttt
     9181 aagaaaataa ttggaaaaaa acagaaaaat atcaagcgct ttttcaaacg ctttaataca
     9241 gcaaaaatct aacatttttt tatgggcttt ttctttgaat tctataataa aaggatagaa
     9301 cttgacttag aaaatcaagt tctatccttt ttgatatctt aacttttgga agagagatgt
     9361 aaggctgctt tctacccatc attcttacta ctcgaagcat agcgcagttg tcacaacctc
     9421 ttgataaacg gtgtttaaaa gcttgcatct gcggtaataa gcccaaccaa attaaaaaca
     9481 taagaagctg tttttatttg gtcgttctta ttacttgatg cagagcagct tttttacaac
     9541 ctcttggtac acggtgttca atcagctgac cctcggtatt agctcaaaaa aacggcaaaa
     9601 tatgaggaac tatttttcca tttttttctc taatactcag gtcaaaacac tgatttcaca
     9661 acctcttttt ttaatgaaaa atatggctct catgcgccgc ttctttgaat ttcgtcattt
     9721 tttcttcgat gaacggatag attgccgttc ctacgattcc aaagacaaca aacaaaccga
     9781 tcatgatcca gattgctttc gtagcatttg gccaataaat tcctcctgca gattcccgta
     9841 acaagtttac cgcatgagta aatggcaaga acggattgat catttggaag aatttccctg
     9901 agacttggat cggatagttc ccgcctccgc cagagatcga cagtactaag atgataatag
     9961 cgatcccttt accgacatta tcgaataatg cagccaagac atagacgatc atcatgaacg
    10021 ctaaggcgat caagacagca aatgacacgc tgtagaccgg attttggaca tctactccta
    10081 gtaagaaaat attccctaat gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg
    10141 tcagcatacg agcaacgaat tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta
    10201 aatagtattc tgtcgtagca acacttgaaa gaagaacagc gccgacccac agacatagtg
    10261 cagtataaaa cggggtgcta gctgaaccgt tatttgcgat tggataaagc gcattggttt
    10321 gtagctcaac aggttgtgta aagaagtcac tttcttttgt tgcgtctagt ttcaataatt
    10381 tgatgacttc gcctagatcg acttcttgtt cgccttttcg gatcgcgtct gctgcttttt
    10441 ggataccagc tttgatattt ggccagtcat tgttgatcaa gtccgcagca gcgttcacag
    10501 ctgtttcgac ttctggcatt ttttcattta ctgttgtcaa tgtaccggtg atttcatttt
    10561 ttagtgctgg ccaatcattt tggataaaat cagcggccaa tcctaatttt tgctgaatga
    10621 tcggtaattc attgttgtat aggtctgccc cttcattgat gccattgacg atggtatcca
    10681 tatttccatt cagcattgta ttggcatcat ggatttcttg tccaattgca ggcatttctt
    10741 tttgatattt ttctaaaatt gccactgcat tcgttacagt tgctttcgtt gagctgagaa
    10801 gcgaatcaaa gtcgatctgg tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat
    10861 cgatgacttg gtctagtaga gaagtgacag tggaactgat ttgacctgta ttgataccag
    10921 caatgatgcc attgatatta ttaacaacgg catcaatttg atctagcaat tcatcaatag
    10981 ccttcgtgtc ttcattttga acagctgtgt tcaaagcaga taggcggttt tgcagattgc
    11041 ttagcaaggg ttttaattga tttagctgat caataattgg ctgtaatttc gtatttccag
    11101 cacttgtttg caatttagtc aggaactcga ccagtttatc gattgcattt tgttgttgag
    11161 atattccgtc aataaagccg ttcaatacat tgctgatgtt tttcttttca tcatcagtca
    11221 gcttaccatc ttcaatagct gttcttacag tatctattaa cgaacctgtc gttgttgcca
    11281 cttgtccaat tgacttcaat gtaacatcta cactgtttgt gatgcttggt atcgcatctt
    11341 tcagctgaga ggcacctgat tttgtttggt ttgctagatc acttgcctga ttttctaaat
    11401 ttttcacatc tggcaagata tcttgtactt gttggatgat cgtcaagcct tgttttgctt
    11461 catcgattcc ttggttcatt gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta
    11521 gttgcttacc ggcattttgg atctctggga ttttttcttg caaatcaagg atgatttttg
    11581 cttgatcttt caactcaggc attttgtcat tcaatgcaac gactttttca cccatctcat
    11641 ctactttagg gatgtaatcc acgaattcat ttgctttatt cagtttttcc ttgatttcag
    11701 gtagttgact ttgtaattcg aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt
    11761 catctgttga taaaatcata tctttaactt tattgatact tactaggttc gtatcgatgt
    11821 cgtaacctat ctcattgaat actttcaata aagtcgaact ggctgttttg ataaattcat
    11881 ttgtgatttg cgattggatc gaacttgctc ctttatcggt gattttcggt gcaatcgcat
    11941 tgattttttc atttaccgta tattcgattt ttggtttctt gatatcacca ctagtaaaac
    12001 tcagcagatc ttctgagaaa tcctttggca agtaaatacc tgcgtaatac tttccggaac
    12061 ggactccgtc ttctaattgt tcttttgaat caacgaattg ccatcctaat tgtttatttt
    12121 tatgaagcga ttcgatgact tgctccccaa tggccacttc tttaccttga aactctgctg
    12181 gcttgtctgc actgtaaaca gcaattggca gctctccagt atttccatat ggatcccata
    12241 atgctttgat gttaaaccac gcatatagcg aagggatgat catgatcgcg atgatcagaa
    12301 gtgttgcaat cgggtttttg aaaatccgtt tccagtcaag caaatataat cgaagcgtat
    12361 ttttgattga ctgcatagtt ctcccccttc ttcttttttc agctgaatta ctttaccatg
    12421 tatttcatac ttttttcaat cggctttttt caaaaaagtc gaatttttgg acatatcacg
    12481 gcaattgtct cattgtaatc tcttacatat tgagaaataa ttaaggatta cagcctttac
    12541 tttatcatga aataaaaggg aaagataatt ttatgccaaa gtttttatct attatacgta
    12601 tacgcaaaaa agctaaaaca ttttttgtct ttgcccctac aaaaatgttt cagctttttt
    12661 cgttttttat tcctgtattt cttatttttc gaatgacagg atgattttcc cagcaggagg
    12721 atgtccttca actagctgat gtgcttggat gacatgctta agtgaagcag acagattcat
    12781 tgaaataaaa acatgaaagg ctcctttttg gtaggctttg attatgccag caaaggcttc
    12841 tgcatctaga tattcctttc ttggaacaaa cgattcataa aagccttcct ttttttgccg
    12901 caaatctaga tctgggaggt catttaatgc aacatacctg ccgcctggtt tcatgatctg
    12961 gatgccggtt tctcctttga tacttccttt cgtcgcatcg attacaaggt ctgcctgatc
    13021 agcaaattgc agacctggat ttgttttatc ataagcagca aatgctgaag ctcctaattt
    13081 ttttaccttt tcctcatttt tactggatgc actggttaag attcggattc ccttttcatg
    13141 gagaagctgg atcagacttg acccgaccgc acctgatgct cctagtatca ttacagtatc
    13201 tgtcggctgg atttccgtca aatggttgat tagattataa gccgtaattc ctggcgtgac
    13261 cattccggct gcttcttccc aactcatttt atctggaatt tttgctactt ttgctgatgg
    13321 caacacgact tcttctccgt aagtcccgcc gactgcatgg acagctactc gatcacctac
    13381 atgaacagtt gtgacatctg aaccaatctc tgtcacaata ccagcgccat cattacctgg
    13441 tacataaggg aatttcaatg ttcgtatctc tttcatttct cctaaacgca aggcaacatc
    13501 ataaggattc acactgaatg cttttatttc tacacgaaca tgtccagaac cgacttctct
    13561 gggatgagca tcgatttctt caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa
    13621 tcttcgcatg gtcaccatct ccctttttct ttaagtttac gtttatgcct ttattttgac
    13681 aaaaaaaatg tcttttcgtt ttggcgcatg attcaaaaca aaatagttgt cttttttcgc
    13741 gtaacgtgtt aaattattta tctaaaagcg taaagattac gatttacgct aataaaaaat
    13801 aattggagga atttgttgat ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa
    13861 gaaacgattg aacgctatgc tgctttacgc caggaattaa aagcgcaaaa agattacgaa
    13921 ggcttgcgta aacttccttt agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc
    13981 gatggacgcc ctcgcggata catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa
    14041 ttagcacata aaggtttgat tccaggagta aaaaaagcca gctggtaatc caagtctggc
    14101 tgtaatgtaa aggaggaggg cgcatggacc actccttgga tcatcaaaaa agatacgttc
    14161 gcttcttcta gcagaaatgc tggtactaga agcagacgta tcttttttta cgcacagctg
    14221 gtcctttttt atatgtaaag gctgcatggt tacttcgcta tatttattta gtaacaggag
    14281 tcagtgcttc gatacccaca ctaattttca atgctcggtc aacttctgcc ataatgggtc
    14341 gatccaaatg gcagaccttt tctttcaatc ttgatttatc gatcgttctg atctgctcca
    14401 acaggataac ggagtctctt tctattcctg ttccagtagc tttgatccca atgtgagtcg
    14461 gaagcttagg tttagccatt tttgccgtta tggccgcaac aatgatcgtc gggctaaaat
    14521 ggttacctag attattttga ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca
    14581 cgactggaga aagatcagca aaataaatat ctcctctttt taccatagga tcctccttat
    14641 tcttgatatt ctcttggtat ccgctgtcct aatccgcaag ccacttcata gtggatcgta
    14701 cctaattgat ctgctatatc ctgcatagtg atttctttgt ctgcattttt gccgataagc
    14761 gtcacttttg ttccgacagg aaattcttga ggcaatcgga tcatcagttg atccatacat
    14821 acacgcccaa tcgtttcaca gtagttccct tctaccaata gagaaaaacc ctgcatcttt
    14881 cgtggccagc catctgcata accgatcggt atcgttccga tccactctgc ttcaggagtg
    14941 atatatgttt ctccatagcc gattccttca cctgctggga gttttttgac ttgaatcaat
    15001 tcagaaacca gctcaagtgc tggctgcaat ggataaactt ccggtagtgc gtgcccagag
    15061 ggattaagtc cgtacattgc tactccataa cgaatcatat tgccgattgt ttcatcatgc
    15121 cataaagccg ttgcactatt gctgacatgt acatatcgag gaagttcggg aagttttttc
    15181 agcacttcta taaagcgttc tttttgcaga ttccaatatg tatcatctgc ctgatctgct
    15241 gtagaaaaat gggtaaataa accttcccat tctaatacac gactttcttt gatgaatgca
    15301 gctgcctctt ttacttcttc aggtgtacaa aatccgatac gacccatccc agtgtctgct
    15361 tttagatgaa tcgaaagagg cgtctctagc ttacttttct ctaaaacagc agctgctgct
    15421 tgcaaccatt cccgtgtacc tgcagttact gataaatcat gagcaacagc tacagtcagt
    15481 gcgtcgtaag gaaccatatt caagataagg atgggctgag taaatccagc ttctctcaac
    15541 tcgactcctt catctaaatt tgaaacacaa aagcccgaag ctccacctgc aactgctgcc
    15601 tcagctgttt caatagctcc atgaccgtat ccgttcgctt ttactactgc aaacaattct
    15661 tttccttgcg gaagtcttgc aacttcattt gctacatttt cagttatagc ttttttatgt
    15721 atcactgctt tcgttgggcg gtgccaagcg acaaccatcg tttttccttc tttctagtct
    15781 tccaaaataa tttgtgcaaa agctgtttca tttgtatgag taatactgac ccatacattg
    15841 ccttcatgag gtgaacgcgt cacaacaggc tgaccatttt cattttttaa aatctcgaca
    15901 tcttgaaagg taacttttcc gatcccagtt ccccaagctt tagagaaagc ctctttgcaa
    15961 gcgtaacgcc cgcctaaaaa ttctacttgg cgatgaaaag gcaaggactg gaatagtttc
    16021 atttcatcag aggtcaagat tcgtgcaatg aattttggtt tttcttcgat cagccgagtg
    16081 atcctaggaa gttcgactgc atcgatccca attcctttta tcatatgctt ttctcttttc
    16141 aataaattta gaacactctc attctaccaa attataacca ttttgccaca aataagtcca
    16201 caaataacaa aaatgaaagt ttctcttaaa aaagagaaac tttcatttta tgtttaatcg
    16261 ttatttgaac ggattacaaa tccgcgtttt ttatcattgt gacgtttacc gccatctttt
    16321 tggctgttat tatttttgct ataaccgcct tttgatttgt ttccacgata attaccgccg
    16381 tcacgacgat tacggttgtt tccgccacca cgtttgccat ttttattgta tccttttttc
    16441 tgcattggca atgggcgttc tggtgtgatc ttcactggca ctgcatcagc tggatctttt
    16501 gctgtcgttt ttagcaaaag tgcaactaaa tcttgtgcag aatattcttc taataattta
    16561 tctgctgttt gcaggtattt atctagacca ttttctgcaa gttttgtttc gatttgttca
    16621 actgcagcac ctaattgacc tttgaatgct tctttttcgg ttggtggacg taaagtcgtc
    16681 atccgttttt tcgtcaagtt ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg
    16741 aaagtcacag acataccgcc ttttccggca cggcctgtac gtccgatacg gtgaacgtag
    16801 ctttctggat cttgagggat atcatagttg tacacatgag tgacacctga aatatctaat
    16861 ccacgtgcag caacgtctgt cgctacaagg atatctaaat gaccgctctt aaatgaacgc
    16921 aatacgctca ttcgtttttg ttgagacaaa tcgccatgga ttccttctgc acggtaaccg
    16981 cgtgcttcta atccgcgtgc caattcgtct acacggcgtt ttgtacgtcc gaagacgatt
    17041 gttaattcag gtgtttgaac atcaaacaag cgagtcatga tatcgaattt ttcgtattct
    17101 tttgcgcgga catagtattg atcgatcaag tcagctgtca tttctttcgc tttgatcttc
    17161 acatgatgtg gatttttcat gaatttaacg ccaatattct tgatagctgg cggcatcgtt
    17221 gctgagaaaa gtaatgtttg tctttgatca ggaacttgtg aaatgatttt ttcgatatct
    17281 tccaagaagc ccatattcaa catttcatct gcttcatcca aaactaatgt ttgaacggtt
    17341 ccaagtttca atgtgtggcg gttaatgtgg tcaagcatac gtcctggtgt acccacaacg
    17401 atatgtggac gatctttcaa gccacggatc tgacggccaa tatctgctcc gccgtaaacg
    17461 gcttgtacac gtactttttt gtcgcgccct aaacgatata attcttcttg tgtttggata
    17521 gctaattcac gtgttggtgc gataactaaa ccttgtaatt cgtgacgatc tggatcgatt
    17581 ttttctaaca ttggtaatcc aaatgcagct gttttccctg tacctgtctg tgcttgtcca
    17641 ataacgtctt ttccagctaa tgctagtgga atcgtttctg cttggatagg cgttgcttct
    17701 tcaaaaccag cgcgttcgac tgatttcaac aattctggtg ataattctag ttctttaaat
    17761 ttcaaatgaa tcctcctata tggttgttaa ctgaggatgt agcttttttg ctaccccgtc
    17821 gatttgttcg gtcaaagtgt attgtttctt tttgacagtg gccacgcacg tttttatcca
    17881 ttcttagccc ctgtggcacc accgaaaaat cactttgcga agtttaggca ttagaaaagc
    17941 caaacgggtc gcgttcagct ttatcattat tatgacatct ggcttcaaca agttgtttct
    18001 atggcaaaac cagtccaatt tctcttcatc tttcggcaat aggttattct aacatagttt
    18061 ttcgttttct gcaagtttac agatttttat ttcatttgct gaagttgttc taccacttca
    18121 aataagccca tgctgttgct gccttttagc ataatactat ctgttgcttc aagattttgt
    18181 ttgatagcat caatcaattt attcttttct ttttccaaat agaacacagg tagttggggg
    18241 tatttttggt tcaattcttc ttttagtgca tgcatttgtt ccccataaag gaaaatcatg
    18301 gcgaatttct caggatcgat atgttcactc atttgcgcat gcatatttaa agactctttc
    18361 cctaattcca gcatatctgc taacacagcg attctgcgtc cttttgttgg cagattttta
    18421 aaagtatcta ataccagtcc catggctgtt ggatttgcat tgtagacatc gctcaaaata
    18481 gctgcaccat ttcctgccgt tagccattcg gttctgtttt gagtgataga aacatgggcg
    18541 agcccttggc gtatctcagg tatggacagt ccaaagaagc gcccgatcgt atacgcaatc
    18601 aaagcattcg ttacattata acttccaggc agcgggatcg taaatgtttc tccttctact
    18661 acaaaatcgg tttgtgcttt tccttttgct gtcacttccg catgaacatc gccatttcca
    18721 ataccgaatg ttgtgactgt ttgtactaat gttgccgtta aaggtgtcag caacggttca
    18781 tctgcgggca caacgagtaa tccgtctgat acaagtccgt cagtgatttc cattttggct
    18841 ttagcgattc cttctcgcga cccaagattt tctatgtgtg cttcaccgat cattgtgatt
    18901 gctgcagctt ttggttgagc cataagtgaa agttccgtga tttcattggc gtgatccatg
    18961 cccatttcca aaacgatctt ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga
    19021 ccaatattat tgttgtaatt tccttgcgtc ttatatgttt tgtatttttc agacaagaca
    19081 gacgcggtta gatctttcgt ggtggtttta ccattgcttc ctgtaattgc aacgacttct
    19141 gcgcctactt tttccaagta ataggttgcc aattgctgca tggctttcaa aggatctgct
    19201 acaggaataa ctggaaaatt ttttggagct tgttcaacag gcaagctcca aaatgaagca
    19261 gatgctccgt ttgtgatcgc ttgctggata aattcatgtc catctcgcgt accagcaaga
    19321 ggaacgaata aacttccttc ggttatcttc cggctgtcaa attcgacatt ggtaatcttt
    19381 gtcagtgcag agcattcgct gcccacggct tgtgcaattt cttgtattgt tagattcatt
    19441 gagatctctc ctaaaaaagg ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg
    19501 actctcactt ccaagtaaat ttctctattc gtatttagaa gctagaatga acgcggttac
    19561 gcaatcactc cagcctcttc tttatttctc tttattcatt tttttcaaaa aaagattgac
    19621 gctgatggta tcgattcatt cctaactgga tcagttcttc aatcaaatca ccgtatttca
    19681 agcccatatt ttcccataag agtgggtaca tactgaactc cgtaaatcct ggcatagagt
    19741 ttaattcatt caggaataat tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc
    19801 cgcttccacc taacatcgtg taagctaact tcgcgtactc ttgcgctttt tgataaactt
    19861 cttctggcac ttcggctgga atctgcattt cgattttatt attgatatat tttgcttcat
    19921 aatcatagaa tgctacgtct tttacgactt caccaggcaa agtcgtccga acgtcttcat
    19981 ttcctaatac agcaacttcg atttcgcgcg cttcaattcc ttgttcaacg attgctcgag
    20041 aatcatactg ataggctgtt gctaaagcat tttgcagctc ttctcggttt tctgcttttg
    20101 taatgccgac actagaaccc atattcgccg gtttgacaaa catcggataa agcaaagaac
    20161 cttcacattg atcaaatact tttttaggat tttctttcca ttgattctta agtactggta
    20221 cataaggaac ttgcggcaca ccagcagctt gtaaaatata cttggtcatg attttatcca
    20281 tggcacatgc actggtcaat acgcctgcgc cgacataagg catattcaat gtctctaaga
    20341 agccttggat cgttccatct tccccgtttg gcccatgtaa aactggaaaa acgatggctc
    20401 cttcttcttt gatttcgccc ggattgatca cttttcctgt aaagccttcc tctgtctgtc
    20461 cacttgggtc ccatgaaaga tgcaagacat ctttgctggc aggtttttct gttagtaatg
    20521 gacctttgac ccattgtcct tcttttgtaa taaatacgag ttgaacttgg taataattat
    20581 aataaatggc atttaaaact gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc
    20641 gtccgccata tagtaaagta atcttcaaaa gattgtcctc ctgtattcta aatcgttcag
    20701 tgatttactc tcatatttta gcacaaaaca aaaataaacg aataacttat ttataaaaaa
    20761 acgagccagc ttctaaaaga acgagcgtca tttatttttt gtcagctaga ttatttgtcc
    20821 cgttttttat aaaaagttat gataaagaaa aggagggatg atgatggcgc aaacaaatcc
    20881 acgcagccgc ttggcagaaa tcattcgagt gttcatcaat tacaatgtag tgccaaactt
    20941 tgtacagcaa aaaaatcccg aacaggtaaa aaaagccttt gaagaactag gccccacctt
    21001 catcaagata ggacagatgc tttctgttcg agaagatttg ctttcttctg ccttcactca
    21061 aacattcaaa acattacaag atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac
    21121 gatcgaaaca gaactttctc tttcattatc agatatattc gatgattttt caaaatcgcc
    21181 ttttgcctct gcttctatgg ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt
    21241 agtcgttaag atccaacacc ctaacatcgc cgaagagatc cgacttgatc ttcaactatt
    21301 tgaacgagcg atccctttga tcaaatacat tcctgaaact agcgtagttg atctaaaagg
    21361 ggtactccaa gaagtaaaac gttccttgat caatgaaatg gacttcttaa aagaaagtca
    21421 aaatggcgaa caattctatc aaaagaacaa tggctggaaa gagatccgca gccccaagat
    21481 ttatgacgct ttttgttcga aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt
    21541 gaatcattta atgaacgccg aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa
    21601 gcagctgaaa caagaagttg caaagctttt agttgagaac tttatgaaac aggtgtttga
    21661 tgatggtttt ttccatgctg atcctcatcc agggaatctg ctattccatg tactaacaaa
    21721 agaagaacag acacaagcta gccgaaaaac tgaaacagtc catgaaaaag agttcggttc
    21781 ctttgctttt cgagcctcca cttctgcaga agaccctgtt gcgccatata ccatcaacta
    21841 catcgatttt ggtatgatgg ggcatctttc tgcaggactt aggcaaaaac tcacacaagc
    21901 cgttttagcg ctgtatacga aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg
    21961 tcagcaagaa ggctcgtttg atgaaagtcg gttccaccaa gaactgacaa gttttcttga
    22021 acagtattat gattctccta ttgatgaaat caacttgcaa gaagtattca cacatgtcgt
    22081 gacgatttgt catcaaaata atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc
    22141 atttgggaca ttagaagggg tgatccgcgt cctcgatcct gaagtttccc tcatggaagt
    22201 cgcttcgcct tttgctcaac attattttct cactcatctg gatgtagaag atacattgaa
    22261 acaaagcgga ttagacttat tggaagggat gaaggctgcg cctaagatcc ctcaacagct
    22321 ccaccatcta ttagaaatgt ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa
    22381 gcaagacaaa ttattgagca ggatcgaaag tatgatcaat cggcttgttt tcggtatgat
    22441 tttagctgca ttgatcgtag ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc
    22501 agaggtcgtt tccttattag ggatatttac gtatgctatt gccgcattcg tcattatttt
    22561 tttggcaatc gatgcattga tccaaatgta taagaagagg aaaaagtaga aaaaggttgt
    22621 gacagaaaga atcagcttca agaaataaga aggggtttta cataaattgt ttctcaaatt
    22681 tttgtgaaaa ttcggcttat ttttcgaaga ggctacttct gaaacaccga gaataaaaaa
    22741 tgtgaaaaag ctgttctgca cccagtaata agaacaatca aaaagggaac atggaacaca
    22801 tttatcctgt ttccctgttc cctttttgat gtattcgagc ataaataaaa taccttcgtt
    22861 acctactatc ttctgtactt ggtaaacctt agtcaattgc cttttttaac gcttgacgaa
    22921 aagacatatg atctttctcc gtaaagggtt ttggaccctt tgtccttatg ccagcttttc
    22981 ttaactttcc actatgataa cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt
    23041 cttttccaga gtgatggaac actcgcacac ccttcggcaa tacaagtgaa gctaaaccat
    23101 aatcttgcgt gatcaaaaag tcattcttct taaccatacc gacgatttta taatccgcac
    23161 tatcagctcc gcggtctacg tagacgattt ggacatgatt agcgtattct ttggtcgtat
    23221 aatggtccac actggtcacg ataaccacgt caagaccata ggattctcct aattttatga
    23281 catcttcttt tactggagaa ccatctccat caatgaatag cctcattctt tttcgccttc
    23341 ttccataaat gataaacagt tactaatccg ctcagtaaaa gaccaacatt gatccatttt
    23401 gccaagataa gcagttgtac actttctatc ggcactgatt catggttcag cgtgatcaat
    23461 aatagatgga ttggctctcc catttctttt gctaaaacaa acaaaagcgt catcaataaa
    23521 aactggtgga tcacactccc tttattttga gtagtatact tgacaacgat ccggcgatcc
    23581 attggaatag ctgtatcagt ttgataatat tccttattta gccagctgcc tgttactacg
    23641 tgccagaaac taagcagaaa gacacctatc gcaaaaccat ttggaatcaa gaggaccaat
    23701 aaagaagaac tcagtccaag caattgcata gccaatggag accatgttaa acgtttcaaa
    23761 atccatggtc cgactatttt tgctgcaatc aagcctgctg cataaggcaa atacataaaa
    23821 atcgaaagtt tttctaatcc gtacagtatg ccaacataaa aactgctaaa taaaaaaagg
    23881 aaattcccta gcattccatt tagaaaagta aacagattta gccagcttgg caacttccat
    23941 tccttcttct ggtgtcctaa aacaaacacg aacaagatga acagcagcaa gaaaccataa
    24001 atagcaagat caaaaagcct ttcatcgaat aacaatcggg catttctcaa aagaaacaat
    24061 aagccaaaga atatcaaaaa taaaacaagc tctcgcgtag ctaccagatt tcttttgatg
    24121 tctttgaaat ccagttcgta acgcggataa tgactaaccg tatggtaggc catgacgtaa
    24181 aaaagtgtat aaatagtaaa gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct
    24241 tgatacagga gaaatagcca gatagctgca aataagtact ttttcccatc catattgata
    24301 aaaccttgcg tcttttcgtg aaaattgacc gtggtattag caggtacaag ccatgctgca
    24361 ctcagcccta gcaaaacact tgaaaaataa aataaaggaa aataaaatac gcctaatatt
    24421 ccaagcaatg aaccagcacc accaatcagc agagcgatca tcagcaacgt gtaactatct
    24481 agaccaaatc gtagactgtt gactaaaaat agtccagtca tccgaaaggc ataaaacagc
    24541 gtaaatggca aaatcgtcag ccaattatgc gagtctgtta gtcccaaaaa taaaagataa
    24601 ggaataaaaa taaccgtgtt acttaagata aagggcgttg tttgtgtaaa attacgccca
    24661 aatcgtttga gtttttcgaa catgacaatg gctccttaaa cagtcttata actaatctgc
    24721 tcttcgattt tagcattaaa ggggaaataa accaatttta cagaatatat tcttgtaaaa
    24781 aaaaatacag aaagaagcat aagcttcttt ctgcattttt acggtacttg attactcaag
    24841 cagacaagcc cttctccaca aaagtcttgc ccgacacccc tgcatccggc aggtgataaa
    24901 gatagaaatc aattatcctg tgcctccaaa atcaattagg agctctgtaa accagagtcc
    24961 ttctcgaccc gtcgcataaa tttactttaa cacagttcct atgtttatgc gagagctttt
    25021 ttcattttat aatcgaccat ttgaaatcct tgaccgatat ctgaaataag ttcttctgta
    25081 atctcaaatc cttcatgctt ataaacctcg attgcttgat gattcccctg attcactcgc
    25141 aaaaagatct ctctttcctt tgtttgcgca gcaagttctt cataccagcg aaaaactgaa
    25201 gaagtcaatc cttgaccacg tactttattt agcaaatata atttacttaa ataaattttt
    25261 ccatttatct cttcataagc agtgtaaccg acagtctttt cttcgctttt taataaaaag
    25321 taggacacac cttctgtcag ttctttttga atctgttttt ttgactgata agttttcagc
    25381 atgtaatcca cttgtttttg accaatgatc ggcacaaaag cttccggcca tacttcttgt
    25441 atgactgcca tcagctcatc cagttcattt tctgttactt ttattttttc catacaccca
    25501 cgtccttttt tacattataa atgaccttgc gcttgatgga ataaaaagag catgatcatg
    25561 ctatacacac ccaccgacca tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa
    25621 gataatttcg tcaaaccagc tactagacag atcaagtcgt ctggcgcaaa gggaagcagc
    25681 aaggtaacaa ctagtacttt tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat
    25741 ttctgatact tttttggcga taaaataagc tggacaaagg ctacgccata gtaacggaca
    25801 agcaaaaatc cgattgcttc cccaatcact aggccaatac aactatataa aagcccaaat
    25861 ccattgccaa acatcagcat gcccgctact gaggagatcc ctcccggcaa aataggaatg
    25921 atcacttgga tcacttgcaa cagaacaaat atcatcactg catacttgcc aaattgctgg
    25981 ataaacgctt gcaaagacgt gctcgatcga aaaatcccat gatgataagc ataaagaatc
    26041 aacacaaaga aaaaaaacag accaataatg ggcatgatct gaagacattt ttgtaaaact
    26101 gatccttttt tagacatcta tattccccac atcttttttc atttattaaa actgcctcct
//
LOCUS       DACCVZ010000035        25882 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.035, whole genome shotgun sequence.
ACCESSION   DACCVZ010000035 DACCVZ010000000
VERSION     DACCVZ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.035"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            157..2217
                     /locus_tag="IVW63_001475"
     CDS             157..2217
                     /locus_tag="IVW63_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859755.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            2300..2869
                     /locus_tag="IVW63_001476"
     CDS             2300..2869
                     /locus_tag="IVW63_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7859756.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(3044..3850)
                     /locus_tag="IVW63_001477"
     CDS             complement(3044..3850)
                     /locus_tag="IVW63_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859757.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            3988..5502
                     /locus_tag="IVW63_001478"
     CDS             3988..5502
                     /locus_tag="IVW63_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HAP7859758.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYSVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(5905..6888)
                     /locus_tag="IVW63_001479"
     CDS             complement(5905..6888)
                     /locus_tag="IVW63_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HAP7859759.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(6893..7540)
                     /locus_tag="IVW63_001480"
     CDS             complement(6893..7540)
                     /locus_tag="IVW63_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7859760.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(7625..8257)
                     /locus_tag="IVW63_001481"
     CDS             complement(7625..8257)
                     /locus_tag="IVW63_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP7859761.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(8273..8824)
                     /gene="coaC"
                     /locus_tag="IVW63_001482"
     CDS             complement(8273..8824)
                     /gene="coaC"
                     /locus_tag="IVW63_001482"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HAP7859762.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(8821..9558)
                     /locus_tag="IVW63_001483"
     CDS             complement(8821..9558)
                     /locus_tag="IVW63_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HAP7859763.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(9555..10544)
                     /locus_tag="IVW63_001484"
     CDS             complement(9555..10544)
                     /locus_tag="IVW63_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAP7859764.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            10801..11343
                     /locus_tag="IVW63_001485"
     CDS             10801..11343
                     /locus_tag="IVW63_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7859765.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            11360..12445
                     /locus_tag="IVW63_001486"
     CDS             11360..12445
                     /locus_tag="IVW63_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7859766.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            12457..13263
                     /locus_tag="IVW63_001487"
     CDS             12457..13263
                     /locus_tag="IVW63_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7859767.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            13264..14091
                     /locus_tag="IVW63_001488"
     CDS             13264..14091
                     /locus_tag="IVW63_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7859768.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            14088..15161
                     /locus_tag="IVW63_001489"
     CDS             14088..15161
                     /locus_tag="IVW63_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7859769.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            15589..18285
                     /locus_tag="IVW63_001490"
     CDS             15589..18285
                     /locus_tag="IVW63_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7859770.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            18362..18850
                     /locus_tag="IVW63_001491"
     CDS             18362..18850
                     /locus_tag="IVW63_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP7859771.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            18862..19356
                     /locus_tag="IVW63_001492"
     CDS             18862..19356
                     /locus_tag="IVW63_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7859772.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            19377..20186
                     /locus_tag="IVW63_001493"
     CDS             19377..20186
                     /locus_tag="IVW63_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7859773.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            20183..21004
                     /locus_tag="IVW63_001494"
     CDS             20183..21004
                     /locus_tag="IVW63_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP7859774.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            21055..23154
                     /locus_tag="IVW63_001495"
     CDS             21055..23154
                     /locus_tag="IVW63_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HAP7859775.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            23151..24269
                     /locus_tag="IVW63_001496"
     CDS             23151..24269
                     /locus_tag="IVW63_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAP7859776.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            24308..25186
                     /locus_tag="IVW63_001497"
     CDS             24308..25186
                     /locus_tag="IVW63_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP7859777.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            25377..25529
                     /locus_tag="IVW63_001498"
     CDS             25377..25529
                     /locus_tag="IVW63_001498"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859778.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
BASE COUNT         8190 a         4486 c         5449 g         7757 t
ORIGIN      
        1 acataagtta ttattccgat tttcttgaaa caataaaaaa tcaaaaaaaa tactctccta
       61 atagtccatc ttcttttgat tttatttata taatgaaatc atcttatgaa aattactact
      121 tcatgtttag acaagagtag ggaggactaa gaataaatgt gttcaaaaag acgttcaaaa
      181 caactaaata aacacgcttg tcgtttagat aaggaacggt cgtgttctga aaaacactac
      241 gttaagttta tgatgcgcac gatgctgatc agtttatctg taggtgtcta tatgcatgta
      301 cccgttcagg caacgacaca aaccatcaag gtcgtacgta cctctgtttc tgagaccact
      361 gattccccta tcactattac tcatactttc actgatgcaa atggaaaaca gctacttcct
      421 gcattgactt cctataataa agtcagttat cctccaacga taaaccacta ctggttaatt
      481 cctaacaaaa cattatggac atcggaaacc ggaagcagtg tgccgctttc tatcttttcc
      541 gatatgactg atcctacaaa aggtgatcag ttaaaacaga tcactgatat tttgaatcat
      601 gctttgacag atataaagga cggtggaagc gcacaagttt cttatgtata tgaaaaagat
      661 tattcacagt ttgaaagaaa gaaaatcgat gttctggcag ggacaaaagt ttcgatatct
      721 gatctggtag aaaggctgaa gaacgcagat ggaacacaag gagatatgtc caaagtaatt
      781 tcaaacaatg ggaatatcgt ggatacgact aatacaggaa catctactat ttccttgtcc
      841 tattttgatc caattgcttt aaaaacaatg actgcatctg ctgtgatcca tgttcgtgct
      901 gatcaaacag ctatcaaagg aaaagatctt cacttaagaa caggagagag ttacgcccct
      961 aaagatcttg ttgaatatgt aacaaaaagc gatggaactt caggaaataa agaagaaatc
     1021 aaaatgaacg ggacagtaga tactacaact ccgggagaat atcccgttgt attaacttat
     1081 atagactcga aaacatcaaa tgtggcagaa acaacagctg tagtttatgt agaagcatct
     1141 gctgcttcat cgactgtcat cactcatttt atagatagtc aaacaaataa agaacttcaa
     1201 gcagaaacac atatgagtag tgtaaatcgt attcctgatt tgcgcctacc tgctgaattt
     1261 tctgatcgag tgccaaatat agatttatcg acttatgaac aaaatgggaa agtcacttct
     1321 atttctgatt ggatgcaagc aaacggatta gacagaaaaa gtcactggtc ggagatcctt
     1381 gaagtacttc actcagaact gatgaataat aggaagcaat caggagggga aattaccttt
     1441 acttatgttt atataccaga caatcgttca ttagaaggtc atgatcttat tgttcatcca
     1501 aacgaaaaaa taaacaaaga agagttgatc caatcagcaa caaattcctt aggtaaaccc
     1561 gtaccgttaa aggatgtatc ggttacaatc aatgaagtac cattggagga tggttatttg
     1621 accaaacaaa caggtgattt tacgattatg tatagttatc atgacccgta ttcactccaa
     1681 gaactccatg ctcagtcact attacatgtt ttaccattaa acaaacagat agatcaaaaa
     1741 gaacaaaaaa gacaagaaga aagcttgtca gaaaaaaaac aacaaatggc tcatgcagtt
     1801 tctccaacag ggaaagtaaa acaaacaaga agcctagagt tagcaagaat atctagaaaa
     1861 atctcagaat ctaataaaac gataaggcaa gaagctcatt tggccccaca agtttctgga
     1921 ttggaaaatg aaattttaga gcctaaaata aaacaacaat cagaaaaaga atttgttgct
     1981 aaacagtcgg aagatcagaa ggaatcagat gaccagaagg aaacgaagaa aaaacgcttg
     2041 tcaactattg attccaccga tgagcatctg cagccgcaag taccacttcc tagtccggga
     2101 acacccgcac ctggtggagg tattccttct tctgctttag gagatttcat gcgaggtatg
     2161 gcaggaacat gggtatacgc taatcgaaat gaatttgacg cagatgactg gttctgattt
     2221 atatctctat ctgttatagt caaataagta gctgagtcat atgttatttg gcataatgga
     2281 gacgaggagg gatagaaaaa tgttagataa aacgttacct tacgcagaaa tctggatgac
     2341 aagaccactt caacaaaatg ttccaatcac gcctttagcg gaaggttttg aatttcgatt
     2401 ttatcaaaaa gaagatgaat ctgcttgggc ggagattgag acttccgttg gggaatttca
     2461 aacgacagat gaagcacttg agtattttca acaaaacttt gctccttatc ctgaagaact
     2521 tgaaagaagg atgttttttg tagagacaaa aaaaggagaa aaagtagcaa cctgtaccgc
     2581 ttggcgaaaa aaatcaagag agcaagtgta tccggttttt cattggttag cagtgaaacc
     2641 agattaccaa ggaaaagggc tcgcaaaagc attgactgcc agagtcttgc aagaatttcc
     2701 taccctccat acggacggac caatctatct tcacacacag acatggagcc atcaggcgat
     2761 tgctctttat aaaaaaatgg gttttacttt tattgctgaa aatctagacg gcacacctaa
     2821 tccagattat gaaaaagtta tgcaggtttt aagtaaatta gataaataac gaaatggtga
     2881 aataagtcct cagtattggg ataaaaaacg aaatagtcat tcctcatatc ttactttttt
     2941 gagttaatac tatcggataa ctaatggcat gccatacatt caaaaaagaa ggggcagtga
     3001 caaaagtatt gtcactgccc cttctcttgt tttttagcat gttttatcgt ttgatttttt
     3061 taggaataaa attcttgatg aacgtaaatt tttggtaatc gtttcgacta tagaggtaac
     3121 caaatacact gaaaacaact gctccaataa aattaacaaa taaatccttc atagtatcca
     3181 tgattcccac gtctaagtaa ccattttgga tgattgtttt atctgtttta ccatctgcat
     3241 tttgactttc aatgattgtc cgagtgatat ctggaacatg atagacagtg tttccgtctt
     3301 tacttaactc cacactattg atttgctgga tgatcgtatc tttttgcata tcgaattgca
     3361 gtaatttatc tgctgaaaat tccacaaact cccacataac accaactgtc atcgaaaaac
     3421 agaaggaaac aactgctagt aataaaggag tcaagttcat ggtttttgta tttttattga
     3481 gcaaataaac aagggaaaag ccgacacccc cagctaaaaa tccgctgaat gcatgtagaa
     3541 aagtatccca cattgaaaaa tagccataaa aatcacttaa ctctcctaaa actgttgaac
     3601 taaaaataaa agataacaaa atgatttcta gcatatttgg aatctgtatc tttaatatct
     3661 tttccagaaa ataagggatt tcaaataaaa ttaatgtcag taataaaagc attgtatttc
     3721 cccagtgttg gttccagacc tgatccacta gcataataac gacgatgata cgtaataaaa
     3781 tatagattcc gtttgtgatt ctacctgcag tttttgtact gttcgtaaaa aaggttttca
     3841 aatgattcat aaaataactc cttcatgtat atccttaatt atactaagaa gcgtgtgttt
     3901 accaaagcta tatgacttaa agaaaaacag agttgatatt gtgaaaaaaa tcacttaata
     3961 tagtataagg agaaaagggg gatacaaatg aaaaaattag ttgctggttt attaacagcc
     4021 gttgcacttc ttgctatgag cgcatgcggc gcagatcaga aaaatacagc gcagacaagt
     4081 tctagtacga aggaatctgc cgaagtatca tcaggcgctt ctgaacaagt atatacagat
     4141 ccaaaagaaa tgaaagaatc ttatgatgtc gtgattattg gagctggtgg tgcagggatg
     4201 gcagcagcta tcgaagcaaa agatgctggg ttgaatccag taattttgga aaagatgcct
     4261 gttgccggag gaaacacatc taaatcatca agcggtatga atgcttcaga aacaaaattt
     4321 caaaaagaag aaggaatcaa agactcgaat gatgccttct atgaagaaac gctaaaaggt
     4381 ggtggaggaa cgaatgataa agaaatgctt cgatactctg tcgatcactc tgctgatgcg
     4441 gtcgattggc tagatcaaaa cggtatcaaa ctggacaact taacgatcac tggagggatg
     4501 agtgaaaaga ggacacatcg tccgtctgat ggctcggcta ttggtggata cttagtggag
     4561 gggttattga ataacgtcca tgagcgggaa atccctattt ttgtcaacgc agatgtgaca
     4621 gacattaaga aaaatgggga aacggtcaat gaagtgactg tacatgttca aggagaagaa
     4681 ccaaaagagg tcaccggaaa agcaatcgta gttaccacag gcggttttgg tgccagcaaa
     4741 gaatttattg aaaaatatcg tcccgattta gctgattata ttacgacaaa tcaagaagga
     4801 tcaactggag atggtatcac catgattgaa aaattaggtg gacaaaccgt tgatatggat
     4861 aaaatacaaa ttcatccaac tgtgcagcag gatgaggggg tcttgattgg tgaggttgtt
     4921 cgcggagaag gagcaatctt ggtcgatcaa gaggggaaaa gatttgtcaa tgaaatggat
     4981 acaagggata aagtatctgc agcaattaca gcattgcctg aaaaatcagc ttatttgatt
     5041 tttgaccaag gcgtgcgtga tcgtgccaca gctattgaat tttatgacca aaaaggatat
     5101 gtcacaactg gaaagacaat ggaagaatta gcagaaaaaa tcgatttacc aaaagaaaca
     5161 ctagcaaaaa cagttgatgg atggaatacg gatgttgcgg agaaaaaaga tgctcaattc
     5221 aaccgtgcca cagccatgga acatgactta tcgtctccga attattatgc gatcaaaatc
     5281 gcaccaggaa tccattacac gatgggcggt gtgaaaatca atacgaacac tgaagtatta
     5341 gataaagaaa accagccaat tagggggtta tatgctgctg gtgaagtcac aggtggctta
     5401 catggaaaca accggatcgg tggaaattca gttgcggaga tcattatttt tgggcgacaa
     5461 gcgggcatac aagcagctcg atttgcttcg gaaaatgaat gaaatagaac gtaaataaaa
     5521 agaggttgtg aaatcagcgt tttgagctaa taccgagggt cagctgattg aacactgttt
     5581 agtgaagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc aagtaaaaac
     5641 agcttcttat gtttttaact tggttggact tattaccgca gatgcaagct tttgaacacc
     5701 gtttattcgg aaaaagagcg tgggacaaaa gtaaagaaca cttttgtctc acgctctaaa
     5761 cacgtataaa cggcggaagc agaagaaatt ccttcggaaa taagctgaaa ttcacaaaaa
     5821 tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc ttctgtccca
     5881 gcctcttttt tgatcagcat gattttattc agttatcttc aaaatgattt ttccgatgtt
     5941 tttgtttgct tccatatatt catgcgcttg tttgactgcg ctgaattgga atgtacggtc
     6001 aatgattggc cgaatcttgc cattttctag aaaaggccca gctttttgca taaaagtttg
     6061 tgcgagctct gctttatact gatcacttct aggtgtcaat aatgtaccaa gcagttggac
     6121 acgtttccca atcaatacac caaggtctat ctcaggcacg atggtcccac ctagcatacc
     6181 aatcaagacc caacgtccat caacggctat agaagctaaa ttcttttccc agtaagaagc
     6241 gccgatgaaa tccaaaataa catcgactcc ccgaccttca gtgatttttc gtacctcttc
     6301 ttgaaagtct tgttttttat agttgatcaa ttcatctgca ccaagttctt tacaaaaggc
     6361 gagtttttct tctgatcctg cagtaacgat gattttcgcg tgagaaagct gtctagctaa
     6421 ttggatcgct gctgttccca caccacttgc tcctgcatgg atcaagacag tttcgccttc
     6481 ttgtaatttt ccaagccagt aaagtgtttg ataagcagtc aaaaaaactt ctgagattcc
     6541 agcagcagaa acatagtcta gcgtatcagg gagaaggatt gcacgatcgg caggcatcac
     6601 agcatattcg gcataaccac ctagattgac taatccgtat acttttgtcc caggagtaaa
     6661 agtggagata tcacttttat tctcaactac ctctccagct acttcgactc ccaaaatagg
     6721 gtagggaggt ttcaaagaga ctgattctct tttcataata tctgttcgat tgacagctgc
     6781 tgtatggact ttgatcagta attcgccttg ttttggttta ggaacaggca cttcaatttg
     6841 ttctaataca tctacagaac caggatgctt gattgaaatg gcacgcatgg atctattcct
     6901 cctttgccca ttcttggaat gctgtattca actctttgct accttcagaa agtactagag
     6961 tcgtacgaga aatatccgtt tcttccacta gagcggcaag tacagcagca actgtagagc
     7021 gagtgatcgt ttttgatgcc ttctcattag gcttagttaa ttgaatggaa gtaacttctt
     7081 catcgttagt caatgtgact ggttgaagaa tgacaaaatc taagttagtt cgtttcagcc
     7141 attcatctgc ataatgttta gtaatataat aatctgtcat ggactcaggc cattttgctg
     7201 gttcatctgc ataaacagca ctgaccatca gatagcgaga gacatgcgca ttttcagctg
     7261 cgatcactgt tttgattgcg ccatccaagt ctacttgcag aagattcttt ccttgagagc
     7321 cggcagcaaa aatcaataca tcgatgcctt tgaatgcttc ggtcattttt tccacggacc
     7381 aagttaaatc aaaagagaca tacgaaacat tctctttttt tactaatgtt tgggaagcaa
     7441 catctctcac ccctgcaaaa atttcatggg aacttggagc taaatctttt atcaggtgtc
     7501 ggccaatttg tccgtttgca cctacaacaa aaattttcat ttggatcatc ctttcgacgt
     7561 caaatctttc cattcaatag taacaccaaa agagaaaaaa atcagagatc ggctacgatg
     7621 actatcagtt agtaagagaa gggtgcttga agtatcttaa caagacattg catactgctg
     7681 cagtcgcaag acctgcgacg attccttcag gtataccact tgtaaaaata accgctagaa
     7741 tagctgaata aacagcattt aaatttgttc cgatgacttt ggcataatct tgctggaata
     7801 aaaagtagat catattcatc actaaaatcg tattggtcaa tgaaccggaa agtccagcta
     7861 agaataaaga aacggaatct gctttttgtt tcattagttt gcgcagacct ttataaacga
     7921 aataaggaac caccccaatc aagatgcgag gaataaacgc gatcagcaag gctttccagc
     7981 ttccatgttc tgttccgatg actgggataa acggagaaaa gacaaaagac aaaggtgttt
     8041 ggataactgt gctacggatc atgctgatca gtccaaatgt accgccaaga aaagcaccta
     8101 gtcttggtcc taaaacgatc gaagcaatga ttacaggaat atgcatggtt gttgcattga
     8161 ttggaccgat agggataaaa cctaaaggcg taacagctaa taaaatcaaa atagctaaaa
     8221 acatcgcagt taatgtaaag ttttttgtat ttttcataag tactcctttt ttctaagcat
     8281 ttctttcatt aagagtcagc atgacctgtt cgatgatcgt ctgaatatca gctaaggcac
     8341 cttttccaaa atctccacaa gctaaaagag attctcttgg ttcaatttcc tgatagccga
     8401 cagatctcaa tgtttccaga ttacgctgag tgatcgggtt ttgatacata ttcgtgttca
     8461 tggcaggggc aatcaatttt ggtgttccca ctggaagcgc cattgcgact gttgaaagaa
     8521 gatcgtctgc aatgccgttt gctagcttgc cgataatgtt tgctgtagca ggcgcgatga
     8581 gaaacaagtc agcttgtttt gctagttcga tatgattgat tacctgcgga tttgattctt
     8641 gcatgacgtc tgtatggact gcgcgcttcg acagagattg caaggttaat ggcgtgataa
     8701 aatgtgtgct gcttttagac ataatcacat ctacctgggc acctaatttg acgaattgac
     8761 ttgtaagatc agcgcttttg taagcagaaa tacttccagt aacgcctagt aagatctttt
     8821 tcattttgat tcctccagtc taattttctc agtaatcaat gcagcaatct cagatttact
     8881 ttgagcttct tccactgttc catctttaga taagagatag ccgtggtgtg tctcgccatg
     8941 gatttccgtc aaatcatttg cgaaaataaa atcagttttg ttatttatca gactattttt
     9001 tgcgactgcc agaagagatt cctttggtac atctactaat agtttgaaac caatgatttt
     9061 tgcttttggc tgccattcac gtagataaga aatgattttt ggtgttttct tcaaaacgag
     9121 cacaagatgc tcggtgttag aagagatctt tgaaacagtg gtatctgtct gttcattttc
     9181 cgcaaaccaa ttgtccagtt cttcttgcgt tgaagaagtg ggtaggtttt ttgccagctg
     9241 ttcttctgaa aaactaaaag caggagtaaa atcactgact gccatactgt ggataatcgc
     9301 atcgtagtgt tcttttttcg ttagttcttc taattgtaaa aataagtcca gtgcagattc
     9361 gatcgtataa atcgttatat tggagtgtct tttcggtttc agtgcttgtt tcgtagtcac
     9421 gtaatcgatt gtggtatccg gattggcagc taaataatca gctaatgctt gccctaatcg
     9481 tcctgtcgaa tgatttgtaa tagcacgtac ttgatcgatt ttttcagtcg ttcctccagc
     9541 tgtgattaga atcttcattt atggtcacct acatttacta gtgttcttcc ttggtgtgtt
     9601 ccagcaagta gtttagatgc tgtttcaggc aattgatcca gagtaatctc ttggacgacc
     9661 agttcatctg caatctgcaa atccgccatc tgttgccata aagaaagacg ttgatctatt
     9721 ggtacattga cagaatcaat tccaatcaac tggatgtttc gcagaataaa aggcaagaca
     9781 gtcgcgttta gtttgattcc cccagcattg ccacataaag ctactgcacc gttataagag
     9841 atcaatggaa gaagactgct tagctgctcg ccacctactg tgtcgatgac atagtcgatt
     9901 tgctgttttc ctaaagcttt tgttgtctct ggcagaaatt catcaggtcg tacgacttgc
     9961 aaagcaccta gactttttag ccatgtgaca gactcttctt ttctggaaaa ggtaatgatt
    10021 gactggaatc ctagtttatg taacagggct atcgctgtac tgcctacacc gccagaagca
    10081 ccagtaacga caactttttt atcggaggtc ataccttgac ggattaaagc gttcacacac
    10141 aacatagcag taaaccctgc tgtaccaagg atcatcgctt gacgcagcgt catatttttt
    10201 ggtagaggaa ctaaccagtc tcctggtact ttttgatatt ggctataacc gcctggatgg
    10261 gtgacgccaa gcccaaaacc agtagcaagt acaagatctt cttttgaaaa acgtggattg
    10321 ttactttgga cgacagttcc ggataaatca atccctggag tcatcggata tgttcgtatc
    10381 acctgaccag actcgctcat tgccaatgca tctttataat tgacatcaga ataggcaatt
    10441 tttaccaaga cttcattttc agccaactca gtaaatggca gatcactgat tgctgtatgg
    10501 aaaacaggtt cctttattac ctgaaaagat cgaaaagcgt tcattcgtga gacactcctt
    10561 ttaaaatttt cttttatcat accataaagc ctactctttt attcttgttc ttccgtaaat
    10621 ttagacaaaa attaggtgaa aaataaagaa tcaaacaact agaatttatt ccaaaagata
    10681 aagaaatatt cagcaaaaaa attttacaaa gggttgcctt tttcaataaa tttcgtatac
    10741 taatacgagt ggtagtaaac aggaagttta ctattagaaa acttcgattc ggaggaaatt
    10801 atggaaattg gtgagaagtt aagaaatttg cgcatccaaa agaatttgac acaagaagaa
    10861 ctaggcgaac gcacagattt gtcaaaaggg tatatttccc agttggaacg agatttaagt
    10921 tcaccatcaa tggaaacatt cttttctatt cttgaagtct taggtgtgac tccagaagaa
    10981 ttttttcatc aagaagcagc gaatctgcaa gtggtttatt caaaagaaga tcatacggtt
    11041 tatttcgatg aagaaaacgg gtatgaattg gaatggctcg tggctgattc gaatgaaaaa
    11101 gaaatggagc ctgtcttgct gacttttgaa ggtgcaggag aatataagac gtttgaacct
    11161 tcattatctg aaacgtttat ttttgtatta gaaggggaat tagagttaag cttaggagag
    11221 acggtctatg tggcaaaagc aggacagtcg atctattatc aagcgacaaa acaacatcaa
    11281 ttaaggaatc atctcaaaaa acgaacaaaa gtattgattg ttgcaacgca atcatatttg
    11341 taatataggg ggtaaaaacg tggggaaacc aatcatttca tttgatcaag tagtgaaacg
    11401 ctatgatgat gaaacagtat taaaaaaagt aagttttgag atcgaacaag gaaaatttta
    11461 tacactgctt ggtccttccg gctgtggtaa aacaacgatc ctacgtatta tagctggatt
    11521 caccgaagct acagaagggg acatctattt tgaagggaaa cggttgaatg atttgccagc
    11581 taataagcga caagtaaata cagtcttcca agattatgca ctttttcctc atatgaatgt
    11641 ttttgataac gttgcttttg gattgaagat caagaaaatg tccaaatcag atatcgaaaa
    11701 gaaggtaaaa gatgctttgc gtatggtcca gcttcctgga tacgaaaaac gggagattag
    11761 tgaaatgtct ggtggtcaaa gacagcgtgt agcgattgca cgagcaattg taaatgaacc
    11821 gaaagtattg ctattagatg aaccgttatc ggcgcttgat ttgaaactac gtacagatat
    11881 gcagtatgaa ctgcgggatc tgcaacaacg attaggaatc acgtttattt ttgttactca
    11941 tgaccaagaa gaagcgttgg caatgagtga tgagattttt gtcatgaata aagggaaaat
    12001 cgtccaaagt ggtacacccg tagatattta tgatgagcca atcaatcatt tcgttgctga
    12061 ttttgttggg gagagcaata tcgtggacgg tgtaatgatc gaagataatc tagttgagtt
    12121 tgttggtaag caatttgaat gtgtcgatgg cgggatgcgt ctaaatgaac cagttgaagt
    12181 tgttttacgc ccagaggatt tgacgatcac gacaccagat aaaggaaaac tagtcgtaac
    12241 ggtcgatact cagctgtttc gtggtgtcca ttatgaaatc atctgttatg atgaacagca
    12301 aaatgaatgg atggtccatt caacgaaaaa agctaaagaa ggaagcaaag taggattggc
    12361 ctttgagcca gaagatatcc atgtcatgcg tttcaacgag tctgaagaag aattcgatgc
    12421 acgtcttgac agctacgaag aatagggggg acaagaatga aaacaatgcg caggatctat
    12481 tccgtccctt atattttgtg gctcggttta ttcgtgatcg cgcctgtatt aatgatcatt
    12541 tatcaatctt tttttgatat gaatgggcaa ttcacgctga ataattatct atcttatttt
    12601 acgtcgggga catcgctttc tatgacgatc aattctgtat ggtatgcatt tttgatcacg
    12661 tttttcacgc tgatcatcag ttacccgact gcttattttt taacaaaact gaagcacaag
    12721 caattatggc tgatgctgat tattttgcct acatgggtga atctgctgct taaagcttac
    12781 gcatttattg ggattttcag tgtgcacggc agcgtgaatc atttctttga ttttatcggg
    12841 atcgggccga aacagatatt attcacagac ttcagttttc tgttcgtggc aacgtatatc
    12901 gagattccat ttatgattat gccaattttc aatgcattgg aagagatgaa tccttctttg
    12961 atcagtgcta gtagagattt aggcgcgaat agctttgaga ccttccgacg agtgattttt
    13021 ccgttatcat taaatggtgt gaaaagtggt gtccaagcag tatttattcc ttctctttct
    13081 ttattcatgc tgactcgtct gattggcgga aatcgggtga tcactttagg aacggctatc
    13141 gaacagcatt tcttggttac acaaaactgg gggatgggtt ctacaatcgg tgtgatttta
    13201 atcattgcta tgttcatcgt gatgctcctg acaggcgaga agaaaaaagg aggtcgctca
    13261 taaatgaaaa aatttaaatg gtcgtatctt tatttaggga tcgtcttttt attcttatat
    13321 gcaccgatct tctatctgat tttttattcc ttcaatgaag gaggaacgat gaacagcttt
    13381 acaggattta cttgggaaaa ttatgaagct gtttttgaag atacacgttt gatcattatc
    13441 gtattgaata cgttcatgct ggctttctta tctgcattga tcgccacgat catcgggaca
    13501 tttggggcta tgggaatcta ttacacgaaa aaacgacgtg cacggacagc gttgttgagc
    13561 atgaataaca tcttattagt ctctcctgat gttattatcg gtgctagttt cttgattttc
    13621 tttacactac taggattcgg attaggtttt cagagtgtat tgctttccca tattgctttc
    13681 agcattccaa tcgtcgtctt gatggtcttg ccaaaattgc aggaaatgaa cgattcaatg
    13741 gtcgatgcgg ctagagacct tggtgctaat aatttccaag tagtcaaaaa tatcattttg
    13801 ccttatcttt ctccaggaat catagctgga tattttatgg catttaccta ttctcttgat
    13861 gattttgcgg ttacattttt cgtcacagga aatggcttta cgacgctctc agtagagatc
    13921 tattctcgtg caagacaagg aatcagttta gaaatcaatg cgctaagtgc gttagttttc
    13981 ttgttctcca tgatattggt cattggatac tactttatta gtaaagaaaa ccgtccaaaa
    14041 cggctgaaga aaaacagaag agtacgcgag ggggtggcac ggctgcgatg aaaaaattac
    14101 aatctctgtt tttaggtatt ctcatcatta ttgcggtgct gctgcttggt gttcgtcaac
    14161 ttgaaaaaac aagtggcatg agtggagcaa aggtacttac catctataac tggggagatt
    14221 atatcgatcc tagtttgatc acgaaatttg aaaaagaata tggatacaaa gtgaattatg
    14281 aaacatttga ttctaatgaa gcgatgttca caaaaatcca gcaaggtggg acaaactacg
    14341 acatcgctat accaagtgaa tatatgatcc aaaaaatgat caaagaaaaa ctagtacttc
    14401 cattagatca ttcgaagatc aaaggattaa ataatattga tccacgattt ttagacttgg
    14461 attttgatcc agataatcag tattcgattc catatttttg gggaacttta gggatcgtat
    14521 ataacgataa attctttgat gcaaatcaaa ttaagcattg ggatgatttg tggaagccgg
    14581 aattaaaaga cagtttgatg ctgattgacg gtgcacgaga agttatgggg ctttctttga
    14641 atagtttagg ctattctttg aatagtaaga atatggcaca gctgacagaa gcagcaaata
    14701 aattgaatca tttaacacca aatgtcaaag caatcgtggc agatgagatc aaaatgtata
    14761 tgatcaatga agaagcctcc gtggcagtga cattttctgg cgaagctgcc gatatgatgt
    14821 gggaaaatga acatttacat tatgtgatcc caccagaagg atccaatctt tggtttgata
    14881 atatcgttat gccaaaaacc gtgaaaaata aagaaggtgc ctatgatttc atcaacttta
    14941 tgctagaacc ggaaaatgcg gcacaaaatg cagagtatat tggttattct acaccaaatg
    15001 aagaagcaaa agcgttattg ccaaaagaca tttcgtcgga cgaacaattc tatccatctg
    15061 atgacacgat ctcccatctt gaagtctaca aagatctagg atcgaaatac ctaggcatct
    15121 ataatgacct attcttagaa ttcaagatgt ataggagata atggcaaaac tcagtaagaa
    15181 tggggactta tcaacgttct aaagagctaa aaatcgtcct ttttctatct gagttttcca
    15241 atcttctacc aaaagcggat gaaacgccgc tttttttgtg ttattttatt ttttctacca
    15301 cgtttttcta ccagagaaaa gtggacaaaa ccattgtaaa atagggcccg agacgggcta
    15361 gtaaatctaa gattgaaaaa gttacagaag gataaagtaa ttggaaacta tgcaaatata
    15421 cttaaccctt ctgtaatcta ttaataaaac taatatatga atccagttca atatttgtag
    15481 ctatgaaaaa acataaaaat catattagat aaaaactaaa ttggtagata aattattttg
    15541 tcagatatct gaggcaaata ttcgactatt tgtgtttcaa agtaaaaatt ggaatacaaa
    15601 tatagaatag acatattgca gccgatagtt tattatgctt ttagacacat taaactggag
    15661 gaaaaaatga aaaagagcgc taaagatcga gtttttgatg agctgatacg actaacaggg
    15721 aatatgtctt ctgtcactgc cgagaaaatt tcgaagaatc taggtatctc tcgtcagaat
    15781 gccagccatt atttgacgag attagtggaa gataaaaagg tcgagaaatt accgggaaag
    15841 cctgttttgt ggaagccttt agatgaatat gcggttgtag ataatacgga gcaaataaac
    15901 gaagcctttc attctgtagt tggtcatgac ggaagtctga gagaggtcat tcaaaaatgt
    15961 atagccgctg tcaaatatcc gcctaacgga ctcagtgtat taataaatgg agccacgggt
    16021 gttggaaaaa gttttttagc cacaaaaatt tttgaatacg ctatccatga gcaaattatt
    16081 gaaaaagatg caccatttgc tatcttaaac tgtgccgatt atgcggacaa tcccgaactg
    16141 ctttcggcaa cactgtttgg atacaagaag ggggccttta cgggggctga aaaggatacc
    16201 gatggtttat tggcaacggc caacaacggc tatctttttc tcgatgaggt ccatcgccta
    16261 tcgaaagaaa atcaagaaaa gctctttcta tttattgata ctggaaacta tcgtccagtc
    16321 ggtgaaaatg taaattggca ttctgctaag gttcgtttta ttttcgccac gacggaaaaa
    16381 ggtgaaaatt atttattaga cacctttgat cggcgtattc aaattagtgt tatgttgcca
    16441 acttttgaag atcgccccat tcgagaacga ttagagctga ttcaattatt ttttcaaaat
    16501 gaagcggatg ttttacaaaa agatattatt gtttcaagag aagccttgtc tttaatgtta
    16561 tctcatccct ttagtgggaa tattggtaag ctgaagaata tcattaaaat cagttgtgcg
    16621 gatgtgtata gtcgaacaca agaagaacca ttaacgattg ggaaaaatga gatcttgatt
    16681 cagttaaata tgctggaatc cgaagtagaa agcttgccga ttgctagttt attgataaag
    16741 aaaaatcaaa agataaaaac ggatcgaatc aaaccgtttg attatgattc gattttggaa
    16801 aaaattactc agctgataaa tgaaggtaat ttcaatgaaa atttttcttc gataaagaat
    16861 gaagtacagc atttggtgca tcacattgat aaggattctt ttttatcaat gagtagaaaa
    16921 ttgatgattc agatgtttag aaaggtctgg gtatccgttt taggaaaaac gtacggattg
    16981 acgacgagtg gacctgttgc agaaattatt agcagatcct atgtcatttc cccaagctat
    17041 aagacagact taaccgggat aaatcgtaca ttagctgcaa atctacctcg gacgacttac
    17101 ttatgtaatc agttcttgga gcatttacca ccgctctcag aaaaggacga gaactttcta
    17161 agactgctta ttgtcgtgac tttatctgat tatgtagatg aatccatcga gctgaagggc
    17221 ctgttgcttg ctcacggaga tagtacggct agcagcattc aagcagtagt gaatcaatta
    17281 tgcggcaatt atgtttttga agcgttggat atgccagtag agagtaatgt gtcagagatt
    17341 gtcgaatcga caaggaattt cgtgaaacgg caagtgaata cagatagtct agtgctgatc
    17401 gtagatatgg gctctttaaa tcaaatttac acacagatca agaacgattt aaaaggggag
    17461 ttacttcttc tgaataattt gacgacttcc attgcacttg atattggctt gaagatgacg
    17521 atgaatgcgc catttaaaca gattgcggag gatgcagcag acaagtattc aatcaatgtt
    17581 caatactttg aaggcttttc tcaaagtagc aacattatca tttcctgtat gtcgggtttg
    17641 gggatttcgg acaaattgaa agatgttttt cgtcatcatt tatcggatga atccatcgaa
    17701 gttttcacga aggactacag agaactacgt gaattaatcg accaaaatga tgaaacttat
    17761 tttgacaaga caaaattggt catcacgact tcggatcttc cacgttcctt ttcaattcct
    17821 aatattaatg tttatgacat cttagacggt gatggagcag ccaatttgga gcatattttg
    17881 agtcctgaaa tgaagccggc agaatttaac cgcttgattc aggagctagt aaaattcttt
    17941 tcgttggaag gaattgcgga ccgtttgaac tttctgaacc caacgatcgt gatgagtgaa
    18001 gtggaaacag tcatttctaa atatgaaaat tactatcatt tcactttaaa tggccgtgta
    18061 aaactaaatc tctatatgca tacggcattg atgatggaac gtttattctt ggctcggaca
    18121 gaaaaatctg aagaaccgaa ttatgatttg aaaccagatg aagatgaatt ttattatgtt
    18181 tctagaagta tttttcaatc aatggagatg aaatataatt ttaaagtcaa tgcttatgag
    18241 ctttcgctgc tctatgaatt attaggaccg tatattcaaa aataaagtgt ctaaaaaagt
    18301 gtctaatctg ttttttttag gttagacact ttttttaatg tgaattaacg tgattaaacc
    18361 aatgttttta aaagttggca caggaattgc ttatataaaa gtgaacagaa agaaaggaat
    18421 taaccatatg aagaaaattc taatagcgac tcacggtcac ttagcttcag gctttcttag
    18481 cagtattcaa ttactgacgg ggaaggttca agagattacg gtgattaatg cttatgtgga
    18541 tgagtgtgat tttgaacagg agttgaatgt atttgtaaac caggtgaacg agcaggatca
    18601 gatttttgtt tttaccgatt tatttggcgg aagtgtcaat cagaagatta ccaaaacctt
    18661 tttggagaaa gagattgctg taactatttt gtctggcttt aatctgccaa ttctgctcga
    18721 aatagtattg gcaaccaagg aattaacaaa ggaggatatt caggaactgg taaataaatg
    18781 ccaacaggaa ttaaagatga ccattcttga tgaggtacat gtagtaaatg aagaggaaga
    18841 ttttttttag gaggaagaaa aatgattaaa gcagtgcgaa ttgatgaacg attaattcat
    18901 ggacaagtag cgatgacttg gacaaagagt ctaaatttaa ccgggttagt agtagcaagc
    18961 gatgaggcgg ctaccaacga tattcaaaag atgacattga agatggctgc accatcgaat
    19021 gtcaaagtca ttattaaaac agttgatgac gcgattcatt tgttaaaaga tccgcgggcg
    19081 aaggacatgc gcttgatggt tttagtccct aatgtcaaag atgcggtaaa agttgcgaaa
    19141 gctttcccaa cggaaatcga attaatgaac gtggggaatg ctgggaaaat gacaccgcca
    19201 tcggaagata agaaaacctt atcaaaggaa gtgatgttaa cgacgtcaga aattcaagac
    19261 ttaaaagaat tagttgaact ttatccagat accgtttttc agcctacacc ggcgatggaa
    19321 aaacgttcag ctatctctat tttgagtgat ttttagaaaa aggaaggaga aaaattatgt
    19381 atgatgcatt tgtagtcgct ttggccgttt ttattggagt tgctggacat gaaatgttcg
    19441 ggatgtccat gctgagtcgt ccgattgttg ttgctccgtt agcaggagcg ttgatggggg
    19501 atttgcagac ggggttgatt gtcggggcgt cactagaagc catctttatg ggtgtcgtca
    19561 atatcggaat ctctagtacg gcggagcctt ctttggctgc tgggctggct acagcgttcg
    19621 caatcaaaat gggaggaaac gtggatgcga ttattcccat tgtctttcca ctagcagtat
    19681 taggattaca gttaatgaat atgatttttt cttttgtatg tggaccgatg gctgctaaat
    19741 ttttcaaatt tgcaaaatct ggtgatcaaa aaggaatcat caatctgcac ttctttatgt
    19801 ggtttgtcca ctatgcgctt tatgctctta ttccattctt tgccgtttta tttggagcag
    19861 atgttgtcaa aagcgtcttg gataatattc cagaggtcat catgaacgga ttaacagtcg
    19921 ctggaaatct gctgccggca gttgggatgg cgatgctgtt acggatgctt tggagtaaaa
    19981 atattgctgt gtggtttttc tttggggccg ttgttatggc gtatctcgag ttaccattga
    20041 ttgcaattgc cgcagttgga acgattattg caattgttat agcccaaaga gatctacaac
    20101 taaaaaatat atctgttcat gcagttcaaa gcgatgctgc tgtaaatgca acgcttgacc
    20161 aagaagagga ggatttcttt caatgaaatt agctgatgga atttctaaag atgagaaaaa
    20221 attggttcgg aagatgtttt ggcgctcgat gactatgtat gcttcggtga atccggtgac
    20281 gatgggcggc ggtggtttcg cctattctat gatgcccttc attaatcatt tctacaaaag
    20341 tgaagaagat cgagctgcgg cgctggaacg tcatacacag tatttttcga cgaccattcc
    20401 ttgcgcgtcc tttgtcatgg ggattgcggc atcgatggag aaggaaaatt ctgaaaaagc
    20461 tggttttgac gtggaaagta tcaacgcgat caaaacgagt ttgatgggac cattggctgg
    20521 aattggcgat tcattgttct ggggagtttg gcgtgtcgtt accgcgggac tagcgatcaa
    20581 cttagccaat gccggaaata ttttggcacc aattatcttt ttagttatgt tcaatatacc
    20641 taattacttg atgcgatact atggcggcgt tttaggctat tcattaggct ctaaatatat
    20701 tgaaaagctg tatgcgaacg ggttaattga aattctgaca aaagctgcta gtatcttggg
    20761 tctgatcatg gtaggtgcaa tgacgatcag tatggtcaaa ttcaataccg ttttgagctt
    20821 ttcaatgaag ggcgaagaac taatgaatgt ccaagaaatc ctcgatagta tttttaaagg
    20881 aattgtaccg ttattggtaa cattgagctg tttcaaatta ctagataaaa aagtcggcgt
    20941 catcaaaatt atttttggaa tggtcgtctt gggaatttta ttgtcattac ttggaatcgc
    21001 atagtaggaa gctgcagcta ctaggctgca gtttttttag caaggaggga aaagatgact
    21061 attaatgaag taatttattc acccaaacac ccatttttta atgctgagtt aaacgacgga
    21121 aatgtgacta cttcaaacga atacagctac tatcggaata ttcctgatgt aaagggattg
    21181 accttcgatg taagtaatca aaagacatta gcaaaccttg atgtttgcgg gacgattcaa
    21241 acgttgacct tttatcgaga aaatttacta actgaggaaa aaccaggtgt ttgggtcaat
    21301 aaacagctct ctcaaaccaa ttcgttatcc ttaaaggttg aagtaaacgg gattgtctac
    21361 catttgtcag aatcggatca tcgtattgaa gtcgatgtga ttcaagactg tttgcctaga
    21421 tatattcatc attattcgac gtttaaggtc attgtagtat cctttgctcc catactggct
    21481 aataagcgtt taagtatgct tgttcaacag gtttacattg tgaatgaaac acacgaaagc
    21541 cttcaagttt cagtgaaaga tgtgccttcg tatcaagaga agtattcgga tcagcaaaat
    21601 gtgttgattt ctcaaaaagg aaataaggac acgatcgcac aacaggaagt ggcaagcttc
    21661 gccattgctt ttgtggaccc aaatgctttt gaagaagtaa tgacttttca ggaatctgat
    21721 atcgaaaaat ggctgaagga aacattgaac tattttgctc agctatttgg gcagctgtca
    21781 atgccaaacg atagagttgt ccatctctat cgtcgtgcac tttatcaaag cttttctagt
    21841 ttcggtatga atcgacaggg acaggtcgtc ggcagcaatt ggggcagcta tcctgctact
    21901 aatcgaattt ggaataagga tatgtattac gcatcattgc cattcaccat gtttgaaccg
    21961 gagttatgtc aaaaaacggt tctatggttt gatcaatatg gcgttaagtt tcctggttca
    22021 aaatttacag gaggtatcaa tcattctctg agtaattcgt tatccagtgc gttactggct
    22081 agtctttatt ttgaacatac tggggataca aaattctttg agcggtgtcc gcaggttcta
    22141 ctgaatgctt caagaattat tgaggacata ttagctcaac gtcggtcagg ggaaccaatg
    22201 ctttttccat ctgtttggtt atcagacgcc tttgcacttg gaaagtatca taccggcagc
    22261 aatctttgtc tttggaaggc ctgtattgga cttgcagaaa tttttgaagc cctagaacaa
    22321 ctgagtctta gcaagcgata caaaaacatt gcctgtaaac taaaggaatc aatttgtaaa
    22381 caaatgacta tcgatggtcc ttttggtgag caatttttgg agggaatcgg tgatgaggag
    22441 aaaacaacct attcagtgaa gcactatcaa aaaccgattc ttgagcaagg gttaatcttt
    22501 ttaagtgatg tgattgtgga tggaaaaatt aatttattga tgcatgatgg agaagaatca
    22561 gacactacgt tgatgccttt ttatcaattt ttagataata aagatcattt atatcagaac
    22621 accatggcct tttctgctag ttctttcaat ccaacctata gcgaggaaat caaaggcatc
    22681 acttggggat tagaatccgg cgccactttt cctggcttta tcactgtttt aatgagcgag
    22741 ctgcacaacc ctcaagcttt cgtaacccga ttagaagaac taatttgttt ggcagattta
    22801 gacggttcgt ggtggtggtg gccgtatcgc ttagaggctc aacaaggaga agtcgtgcga
    22861 gactttggct gcggcaaatg cggctgggca tcgggtcttt ttgtcagcct aatgatcagt
    22921 caatatttcg gattgaaatt caaaaaagga gtattgcaaa ttgatcctgt tgataattta
    22981 acgttttctt ggaagaattt gaagttcggt caagccttca tttcgattga atgtacgcaa
    23041 tccgagttga gtatttcaaa tttgtcagaa aagccattga aaataagtga tacgaaaaaa
    23101 attcttcacg tagaaaaggg aaaaacgatt cacattcaaa ggagaaaaag atgagtatac
    23161 taaaaaatat tacccaattt aaaaaaatcc agagtcgagc aatcactccc gaaaatccaa
    23221 caggcgagaa aggtaaagct gcgatgttgc caagcgagct aggaccaagc cgcaaaggtc
    23281 gtggcgcaat tccgctgact tctggtgaag aaactgtgat tgcggatatt actggaacgg
    23341 gaataattcg tcatatgtgg atgacgattc gtgatcgaac agaatttggc agttttgttt
    23401 tacgtgattt aatcttaaga atttattggg atgggtcgga tagccctgct gttgaaagtc
    23461 ctttagggga tttcttttgt aatgggtttg gagagcgttg cgaggtgaac tcgttgccga
    23521 tagtggttaa tcctacaggg ggctttaatt cctatttcga aatgcctttc caaacatccg
    23581 ctaaaattac gatcgagaat ttacatccga aggatatgtc ctcatttttt tatacgataa
    23641 attacgcttt ggtggacgaa ttggaagaaa atagcctata ttttcacgca aattggcatc
    23701 gggaacgcat taccaaatta caggaggatt ataagttaat tgatcgatta aagggtcaag
    23761 gctattacgt gggtacttac cttgcgctta cctgcctaga acgttattgg tggggcgaag
    23821 gcgagtttaa attctacatt gatggggata gtgagtatcc gaccgtaacc tcaacaggtt
    23881 cagaagatta ttttggcggg gcgtgggcct ttcatgagta cgatgagttc ggacgtccac
    23941 atgcgaaaaa ctattcaaca gcctttttag ggtatcctta ccaatcaaat agagatgcca
    24001 caagagatcg ttttgaaacg ggaaaattga atgccgttca tgcctttggt gacgacgcaa
    24061 tgccacgaca tggtctttat cgttggcatc ttcaagaccc catctgtttt accgaagatt
    24121 tatcggtcac tttacaacaa atcggcaacg atgatgttcg cttatttgag cggcaagacg
    24181 atgttgctag tgtcgcttac tggtattcaa cagaagcttc aggaaatact aaacgtcatt
    24241 tcactgatcg agaacgcttg ccgcgttaat gaagtgtttt tcacatattc gaagggagga
    24301 acctatgatg atatatgggg caattgaagc tggagggact aaatttgtct gtgcagtcgg
    24361 tactgaggaa ttaacgattt tggaaagagt cagttttccc acaacaactc cagttgaaac
    24421 aatgaagcag gtcattgatt tttttaaacc ttttaaggaa caattggcag gcatcggggt
    24481 cggctgcttt ggtccaattg atattcaatg caaatcaacg agtttcggtc atatcacatc
    24541 aacaccaaaa cttgcttggc aaaatttcaa ttttgtagga acgctaaagc aatatttcaa
    24601 tattccgatt gaatggacaa cagatgtcaa tgcggcttgc tatggtgaat atgttgctgg
    24661 ttctggcaaa gggttagcag gtgttgcata cttcactgtg ggaacaggta tcggaggtgg
    24721 tgccttgttc aatgggactt tcgtggaagg gttcagtcat ccggaaatgg ggcatatgtt
    24781 gatcaagcga catccaaagg acaatttttc aggaaactgt cccttccacc aagattgttt
    24841 agaggggatg gcagcaggac cagcgattga aaaacggttg ggtgtaaaag gccagaattt
    24901 attggctgac gattcgtttt ggcagattga agccttttac cttgcccaat gtgcatacaa
    24961 tacaacactg atgttttcgc cagatagaat tatttttggc ggtggtgtaa tgaaacaaga
    25021 acacatgaag aaaaaagttc aggataaatt tgttgagctt ataaatggat atgttgaaat
    25081 accaccaatt gatagctaca ttattacgcc cgaattaggt gataatgccg gaataatcgg
    25141 cggattagca ttggccagaa aagcggtaag aaataagcaa ccataattaa tgaatgtttc
    25201 attgatactc atgtcaaaag tatttaaccg agtaatcaaa tgatcaaatg aagttggata
    25261 aagcgaaaat gaattcaaat aaaaaggctc taagtcaaat cgtgttgttt tcattaaatc
    25321 actgaaagga aatgcttctg cgtttccttt tttctttttg ttgtgcgctg tataccttga
    25381 ggatattcac tggtggcgta cacttaaata gtaatatatt gtgttacttt atgtctgtgg
    25441 taatagttat agttgcttac caatgtatgt tcatttttcg aaatgttgac ttcataatcc
    25501 ttggcttaat gtttgaattt ttttggtgat agattttttc agccgtataa aataaatcgt
    25561 aattctatta tagagagttg tgattataaa aagatagcaa gaaaaaaaaa gaaagtttct
    25621 atacatttta aatattttat tcctatttct attgctaaaa aagtagaaat tctatattta
    25681 cctttaactc tcgcttctct tgcaaatgta gttagcattt taatcgataa taaactcagg
    25741 tagttatatt accttgaaat gattgataat tttgtcactt ctattttttt tgcaataaat
    25801 tttttatttt agtgaaaaat aagaaactat ttctttgaag gcgataagtt agaaaaatat
    25861 tattgtagtc ttttctttat ta
//
LOCUS       DACCVZ010000036        25752 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.036, whole genome shotgun sequence.
ACCESSION   DACCVZ010000036 DACCVZ010000000
VERSION     DACCVZ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.036"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..397)
                     /locus_tag="IVW63_001499"
     CDS             complement(<1..397)
                     /locus_tag="IVW63_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7859779.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYF"
     gene            670..3141
                     /locus_tag="IVW63_001500"
     CDS             670..3141
                     /locus_tag="IVW63_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP7859780.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3244..4980)
                     /locus_tag="IVW63_001501"
     CDS             complement(3244..4980)
                     /locus_tag="IVW63_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAP7859781.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4977..5681)
                     /locus_tag="IVW63_001502"
     CDS             complement(4977..5681)
                     /locus_tag="IVW63_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7859782.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5812..6315
                     /locus_tag="IVW63_001503"
     CDS             5812..6315
                     /locus_tag="IVW63_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAP7859783.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6275..6613
                     /locus_tag="IVW63_001504"
     CDS             6275..6613
                     /locus_tag="IVW63_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAP7859784.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6634..8052
                     /gene="ffh"
                     /locus_tag="IVW63_001505"
     CDS             6634..8052
                     /gene="ffh"
                     /locus_tag="IVW63_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAP7859785.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8164..8742
                     /locus_tag="IVW63_001506"
     CDS             8164..8742
                     /locus_tag="IVW63_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAP7859786.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8746..9267
                     /locus_tag="IVW63_001507"
     CDS             8746..9267
                     /locus_tag="IVW63_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP7859787.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9346..9900)
                     /locus_tag="IVW63_001508"
     CDS             complement(9346..9900)
                     /locus_tag="IVW63_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP7859788.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            10153..10428
                     /gene="rpsP"
                     /locus_tag="IVW63_001509"
     CDS             10153..10428
                     /gene="rpsP"
                     /locus_tag="IVW63_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAP7859789.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10440..10691
                     /locus_tag="IVW63_001510"
     CDS             10440..10691
                     /locus_tag="IVW63_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAP7859790.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10816..11607
                     /locus_tag="IVW63_001511"
     CDS             10816..11607
                     /locus_tag="IVW63_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859791.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11777..12298
                     /gene="rimM"
                     /locus_tag="IVW63_001512"
     CDS             11777..12298
                     /gene="rimM"
                     /locus_tag="IVW63_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAP7859792.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12288..13049
                     /gene="trmD"
                     /locus_tag="IVW63_001513"
     CDS             12288..13049
                     /gene="trmD"
                     /locus_tag="IVW63_001513"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAP7859793.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13185..13532
                     /gene="rplS"
                     /locus_tag="IVW63_001514"
     CDS             13185..13532
                     /gene="rplS"
                     /locus_tag="IVW63_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAP7859794.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            13905..14567
                     /locus_tag="IVW63_001515"
     CDS             13905..14567
                     /locus_tag="IVW63_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859795.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            14646..17873
                     /gene="fss3"
                     /locus_tag="IVW63_001516"
     CDS             14646..17873
                     /gene="fss3"
                     /locus_tag="IVW63_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAP7859796.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            17987..18301
                     /locus_tag="IVW63_001517"
     CDS             17987..18301
                     /locus_tag="IVW63_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP7859797.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            18314..18688
                     /locus_tag="IVW63_001518"
     CDS             18314..18688
                     /locus_tag="IVW63_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP7859798.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            18698..19042
                     /locus_tag="IVW63_001519"
     CDS             18698..19042
                     /locus_tag="IVW63_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAP7859799.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            19113..20258
                     /locus_tag="IVW63_001520"
     CDS             19113..20258
                     /locus_tag="IVW63_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAP7859800.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQCATCF"
     gene            20973..22832
                     /gene="ltrA"
                     /locus_tag="IVW63_001521"
     CDS             20973..22832
                     /gene="ltrA"
                     /locus_tag="IVW63_001521"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP7859801.1"
                     /translation="MNKVKTNKTLRHSEYYGMTQIFDELYVKSDKKEVFTELMTIIMS
                     DENIRLAYRNIKNNKGSYTASTDKKSIRDIKTLSEDTFLTEVKVLFRCYKPRAVRRVE
                     IPKPNGKTRPLGIPSIWDRLIQQCILQVLEPICEAKFHNYSYGFRPNRSTHHAIATCN
                     RLANRGKLHFVVDVDIKGFFDNVNHSKLLRQMWTIGIRDKWLLGIIRSMLNAPIVLPT
                     GKVEHPKKGVPQGGVLSPLLSNIILNELDWWVASQWQNTTIETEKIMDRRDKGKGIDK
                     TNQYRALRRTNLKEIYIVRYADDFKIFCRKRSHADKIFHATKMWLKERLSLEISEEKS
                     KIVNLKKGKSEYLGFELKLIKKGKKYVVESHMSKKSMTRVKIQLKKQLRKVARPKNHC
                     EQAKEIGLYNSMVIGIHQYYGIATCVNLDCSKIAYTLKPFINHKLPTKKHGKILNTFI
                     KSKYGKSKEMRWLNNVPIVPLNYVQFRLAVPLSEGTCKYTESGRSKIHSKLKLDLALL
                     LHMMRNSNYERSIEFVDNRISKYSAQKGKCAITGKFLEYEEIHCHHIVPVKQQGTDKY
                     SNLIIIHKNVHALVHAIEEKIIHKYLNVLNLTNEQIEKLNELRVKAGNSVLTV"
     gene            22926..23177
                     /locus_tag="IVW63_001522"
     CDS             22926..23177
                     /locus_tag="IVW63_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAP7859802.1"
                     /translation="MTSKDYLSLFNFRVALGRMSELGYSMMFGEVDKKFFMKRIKGRG
                     YVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG"
     gene            23237..24379
                     /locus_tag="IVW63_001523"
     CDS             23237..24379
                     /locus_tag="IVW63_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HAP7859803.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            24404..24658
                     /locus_tag="IVW63_001524"
     CDS             24404..24658
                     /locus_tag="IVW63_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859804.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            24914..>25752
                     /locus_tag="IVW63_001525"
     CDS             24914..>25752
                     /locus_tag="IVW63_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP7859805.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGR"
BASE COUNT         8685 a         4543 c         5440 g         7084 t
ORIGIN      
        1 cgaagtactt cttagcgatt agtttacgtg attgattttc gtacagttcc atgagaatcg
       61 cctgcttcag ttcctttgtt agttgatgat gttcatcaac taagtccgtt ttcgcagaaa
      121 aggtccttcc acaatcatgg cagagaaaac gggtacgttt taattctaaa atagttaact
      181 tttctttgac tttcaacatc tgagtgcgtg tcgtatagga accgttgcgg ataatacgaa
      241 ccgatcgaca gtgttcacaa taggaagaag agtcatccaa ttttccttta ataaactgcg
      301 cttgaacgcc tttatattct ttttcaatca gccattcttc atcaaaaaat aaatgtttat
      361 ctgttaatcc gagtaatttt ctagtatgat tatccattga gagactcctt tggtaggatg
      421 acgttttggt cgactaaatt ttaccaaaag tgagtctctt tttgagttga aacgaagaaa
      481 aagtgttagt agaaaatcgc cttcgatttt ccaccaacac aaaatattat agaacccttt
      541 ttttttgcta tatgacagga atgaaaggtg tttgcaagct taatgtgagg aacactttcc
      601 atatctgttc tatactggat aggagaagtt tggaaatatc cagaaaacga aatcaatcga
      661 ggtagccaca tgaagaataa atggataaat cgaagtaaaa aaaagaaagt aacacaaaga
      721 tcatcagata aagtcatccg tctttttcca tcgtataaag aaggattaac ggcagatcaa
      781 gtcaaggaac gaatagaaaa aggtgcagca aataattcag tcgatcccac attcaaaaca
      841 aatcagcaaa tcgtattgga aaacatattt acgtatttca atttgatctt tcttatctta
      901 gccattttgc tttgtttagt agaatcctat aagaacttga cttttttacc agttatcata
      961 gccaatacag gaatcgccat ttttcaggaa attcgatcca aaaagatctt ggacgaacta
     1021 aatgttttaa atacagcaaa agtcaatgtc atacgagacg ggatagaaca aacaatagat
     1081 atagaagacc ttgtaataga tgacattgtt attttagaga ctggatatca aattccagca
     1141 gatgcagagg tcgtggaagg gaaactgcaa gttaatgagg ctttattgac aggcgaagca
     1201 gatgaaataa ccaaagaaat aggtgatcca ttaatgtccg gcagtttcat tgtttccgga
     1261 aaagcttacg cccgattaga caaagttgga gcagattcgt atatttccca gctgacagtc
     1321 aaagccaaga caatgggaga aggagaacag tcggagatga ttgcttctct taatcaattg
     1381 atcaaatgga ttgggatcat cattattcct atcggtatcc tgcttttttc tcaaagttac
     1441 ttttttaatg gaaacacgat caaagaaagt gtcgttgcaa tggaagcagc attgatcggt
     1501 atgatacctg aaggactgta cttgctgacg acgattgcat tagcattaag tgcgactaaa
     1561 ctagcaaagc aaagagttct tttacacaat atgaaaagca ttgagacatt ggcaagggta
     1621 aatgtccttt gtgtagataa aacaggaacg atcacagaaa ataaaatgtc tgttcaaaaa
     1681 atgatcgtct ctaaaaaaca agaaataatc agtcagtcag atcaattgga agcatgcatt
     1741 gctgactatg caaaagcgat ggcaggagac aatgcaacaa tggaagctgt taaagcatat
     1801 tttacaaaaa ccactgatca atcctatcac catgttattc ctttttcttc tgtccaaaaa
     1861 ttcagcagtg tagcgttggc agacaaggtg tatgttttag gagcgcccga aatggttttg
     1921 cgcgatcaat tgccggaata tgcggaagag tttgtttctt tcgctgaaaa aggctatcgc
     1981 gtgttggtct ttggtgtgta cgatgggatt cttgaagaac cagtattgac agaagcagtc
     2041 acaccattag gctatattct gattgctaat cctatcagaa aagaagcaag agccacattt
     2101 gattacttca aaaaacagca agtagccatc aaagtgattt ctggagataa tccgctcacc
     2161 gtatccaatg tagctgtcca agcagggatt tcacatgctg atcagtacgt tgatgcatct
     2221 aaattatcag aagaagaata tgaagcagct gtcgaaaaat atacagtttt tggacgcgtc
     2281 aagccagaac aaaagaaaat cttcgttcaa ttgataaagc gtaacaatac agtagctatg
     2341 acaggtgatg gcgtgaatga tattctagcc atgaaagaag cagactgcag tatagcgatg
     2401 gcttccggaa atgaagccgc catgcaggcc tcacaagtgg tcttacttga ttctgacttt
     2461 tcacgcatgc cagaagttgt tgcagaagga cggcgcgttg tgaacaatat tgagcgatca
     2521 gccagcttgt ttttagtgaa gaatattttc tcctttttgc tctcactgtt ttcagtgatc
     2581 tttgctctga cctatccttt agaaccatca caaatcacat tgattagttt gtttactatc
     2641 ggacttccat ctttcttgct tgctctagaa gaaaacaaaa agcgaatcag agggaaattc
     2701 atcatgaatg tgatggaaaa agctgtgcca ggtggactaa cagatatgat cgtagtcggt
     2761 gcgttggtga tctgcggggt gactttgaat ctaaataaaa cagatgtttc tacagcatct
     2821 accatgcttt tgattgcagt agggttcctc gttctctata aaatctgttc accgctgaat
     2881 aaattcagaa gtcagatcat tcttttctgt gctagcggta actttttttc ggtcatcttt
     2941 ttgcataagc tgttttcaat caccggtatc tcagctgtat cacttttgct gttgagcatt
     3001 ctatttttct cggcagattc gatttttagg catttgacca cattggtaga atatttgttt
     3061 gaacgtaaaa atgaaaaaga gcaaaagccg tttagtcgcg tagctaaaaa atttctatcg
     3121 atatttaaac gagaaaattg acgaaaagta tctcaaaaaa gagtaaaaaa gaacaaccac
     3181 tcgtgtatct ttcgaagcag gatgagtcat ccaactttaa aacgcacgag cagttgctct
     3241 tttttacatt ttcggaatgg taacggtgaa agtcgaacct gttccaagat gactgtctac
     3301 agtaatcgta ccattaagga gttgcacgta gtcttttaca atcgctaacc ctaatccggt
     3361 cccgcctgaa tgtcggcttc gcgccttgtc tacgcggtaa aaacgctcaa agatccgttc
     3421 ctgatcctca atgtcgatac ctataccaaa gtcttggaca gaaaacgata gatcatctgt
     3481 tgcctgatag cggataataa tctcgctgtc gctttttgaa tattggacag cattttcaat
     3541 cagatttttg ataattggat aaaggatatc tgttttagta gtaaatggtt cgttctttcc
     3601 aatcaatcga atcgtcaacc gtttcttttc gatgattggc tgataatttt gaacgatttg
     3661 ctggaaataa ggttctgtat aaattgtctg gatctcgtaa gaattctcgc catcttttga
     3721 cagctggatg atttcccgaa tcagtttatc taaccggatc gcatcttttt gcatgatctc
     3781 aagaaaagaa gtcagagttt gcgggtcatc ttttgcacca tccagtaaag tctcggtaaa
     3841 accaatcagt gaagtcacag gagtttttaa ttcgtgagag acgttgccaa cgaaatcctt
     3901 ttgtagcttt tctaaacgtc gcactttcgt taagtcatac gccaccccta gaatctgtcc
     3961 ggtaccttct gaattagtaa agtagcgcaa actcaagtct aatgtctgcc gaccttctgt
     4021 aagggtgatc tcctgatgga tcagcggatg ctcaggagtc acttgatgaa tcagctgaat
     4081 gagttttggc tcttgaatga cttctgtgta ccgctgttca ggttgatagc ttaccacgtt
     4141 taaatgtagc tgcatctttg gattaagcag tagtaaacga gaatcagcat catcaatcag
     4201 gaatacgcca atcatcagtt cgttcagtaa cgtatataat tgctcttctg tggtagtaca
     4261 cgcccgatac atcttactca tttgttcgct caacgcatta atcgtctgat acaattcttc
     4321 ccattgatcg ggtgtttgca tgattacttc cgcctgatta ggattttgca ccattttttt
     4381 tagtacgggc agcacggttt tcaatggctg gtttttttga tagatcagat aatagatcat
     4441 tcctgcaaga acaaggaaga aagacagaaa gaagaaaaag acccaacggc gaaaactctc
     4501 agttctcggt aaaaaaacgc ttgtcggttc tgcgatacgt aaaatggctt ctaactggcc
     4561 actttttttg actggtaatg cgacatataa aagatcctca ttcaaagtag tacttttgcg
     4621 caaagcgcta cctaggttcc caccattcaa tacggctttg atttcgggac gggagtttcg
     4681 ctgttcattc aatgtttcat tgtttgtgtc aaataagatc tttccagtag catccattaa
     4741 agtaatccgt tcgttcgact gatggacgaa ttcttccaaa gcagttttgt tttgcgctgc
     4801 ttggaggttt tcgacatcta attgccggat cagcagttgt gctttttttg tcaggtagct
     4861 ttcttgctgt tccacgatct gctgttgaaa ataatgggaa atcaattgcc agccaccaaa
     4921 aaacaaacta actaaaagaa taagaaagaa gagacgttca taaatttttt tccatttcat
     4981 cgtttgggtt cctgaaactt atagccaaat cctctaatag tcaccaagta ctttgggtgt
     5041 tttggatctc gctcgatttt ttctcgcaaa tgactaacgt gtacatctac gattcggctt
     5101 tgtcctgcga agtcaaaatt ccaaatgcgg tctagcaatg tgtctcggtc gatcacacgg
     5161 tcttttcgtt tcatgaaata aacaagtaat tcaaattctt tcggtgttag ttcaatcaga
     5221 tggtcgtcta cggtcacttg ataattggtc aaatcagcag tgatttgtcc aatcgataga
     5281 tattcaggct cagcttcatc ttttgattgc ttacgaggtt caattcgtct gaatattgct
     5341 ttcatacggg ctaatacttc gcgaggacta aatggtttgg tcaaatagtc gtcagcacct
     5401 atttctaggc caatgatccg atccacttgg tcatctttag ccgtcagcat caaaatcggt
     5461 gtttcatttt tttcttgacg cagccgctga gtgatctcca tgccatccat cgttggaagc
     5521 atcacatcta aaatgatgaa atcaaatgat tgttctaatg ctaattctaa tccttcgcct
     5581 ccatctgtgg cactggttac cttgtagcct tctttttcca aattgaacgt caagagcgtt
     5641 acaatagaag gttcatcatc aacaactagt atttttttca ttcaaatctc ctttaaatag
     5701 gtttcattct gtttatattt tagcatagaa tcagtacaaa gggctatttt acaaaagaaa
     5761 taaatggtat aataggaagg cactttgctg aatagaaagg aagagcagtc aatgattgga
     5821 atcagtgcat gtttaggcgg tctggcctgt cgctatgatg gacagaaaaa agaagtacca
     5881 gaattgatgg aactagttga aactggagaa gctgtcatgg tctgtccaga agtgatcggc
     5941 ggattaccaa ttcctagaga tcccgctgaa atcattggtg gaaatggatt cgatgtgtgg
     6001 aaagatcaag caaaagtatg gacgacaagc ggcgaagatg taacggaagc gtacaaaaat
     6061 ggcgcgatca aagcctatca aaaattgcag gaaaaacaca ttgatctagt catcatgaag
     6121 gaaaaaagcc cttcatgcgg aacccattcg atttatgacg gaagtttttc cggaataaaa
     6181 aaaaatggtg ccggagtggc tactgcttat tttattcagc aaaaaatgac tgtgctctct
     6241 gatgaagaat ggctgaaaac tagaggtgag cagaatggaa atcgaaaaga ccaatcgaat
     6301 gaacgcgctc tttgaatttt attcgacctt attgacagaa aaacaaatga actacatgga
     6361 attatattat gcagatgatt tttcattagg tgagatcgcg gaagaatacg aagtaagccg
     6421 acaagcagta tatgacaata tcaagcggac aagcaagatc ttggaggatt atgaaaaaaa
     6481 actccatctt ttttctaatt atattgttcg agaacaggta ttggaaaata tgactgcata
     6541 tattacagat aagtacccgg aagataaaaa actacttgaa tatgtacagc aaattcaagc
     6601 aatcgaagaa taaataaaag gaatgaagaa aatatggcat ttgaaagctt aactgaacgt
     6661 ctccagcagg cgatgggaaa aataagaaaa aaaggaaaag tatcagaagc tgacgtaaaa
     6721 gaaatgatgc gggaaatccg ccttgcctta ctagaagccg atgttaactt gcaagtagtc
     6781 aaagatttta ctaagcgcgt acgcgaacgt gcggtagggg cagaagtgct ggaaagttta
     6841 tcacctgcac aacaaatcgt aaaaatcgtt gatgaagaat tgacgatcac acttggttct
     6901 gaaacagcag agttaaataa atcaccaaaa ataccaactg ttatcatgat ggctggtctt
     6961 caaggggcag gtaaaacgac ctttactggt aaattagcca attatttaaa gaaaaatgaa
     7021 aatgctcgtc cgctcctaat cgcaggggac gtatatcgac cagctgcgat cgaccaattg
     7081 aaagtattag gtcaacagct agacgttcct gtatttgata tgggaactga agtcagcccg
     7141 gtagagatcg tccgtcaagg gatggagtta gcaaaagaaa agaaaaacga ctatgtattg
     7201 atcgatacgg caggacgtct gcatatcgat gaaacattga tggatgagtt gaaacaaatc
     7261 aaagaattga cgcaaccaaa tgagattttg cttgttgtcg atgccatgac tggtcaagat
     7321 gccgtcaacg tagctgatag cttcaaccag caattaggta ttacaggggt cgtcatcact
     7381 aaacttgatg gggatactcg aggcggggca gcactatcga tccgctcagt gacaggcgca
     7441 ccaatcaaat tcatcggttc tggtgaaaaa ttgactgact tagaagtatt ccacccagat
     7501 cgtatggcta gccgtatcct tggtatgggg gatatgctga cattgattga aaaagcgcag
     7561 caagactacg acgagaaaaa agcggaagaa cttgcacaga aaatgcggga aaattcattc
     7621 gatttcaatg actttattga acagcttgat caagtgatgg gtatgggccc actggaagat
     7681 ctaatcaaaa tgatcccagg aatgaatcaa gtccctggaa tcgaaaacgt caaggtagat
     7741 ccaaaagatg ttgaacgcaa aaaagcgatg gtttattcta tgacgccagc agaaagagca
     7801 aatcctgatc tgttgaaccc aagccgtcgt cgccgaattg ctgccggttc tggaaacagt
     7861 gttgttgaag tgaatcgaat gatcaaacaa ttcaaggaat caagaaaaat gatgcagcaa
     7921 atgtccaaag gggatatgaa catcccaggt atggaccaaa tgtttggttc aggcgtcaaa
     7981 ggaaaactag gcaaaatggc gatgaatcga atgatcaaga aaaataagaa gaaaaagaaa
     8041 aaacggaaat aagatgaaaa aaacagcttc ggtacagact gaaaatgtct actgccggag
     8101 cttttctatc agcaattttt attctttact aatacaatta ctctaaacga agaggtggca
     8161 cagatgagat gtccgtggag tgaacaaaca gaaagtatgc ggcaatatca tgatactgtc
     8221 tggggtgttc ctgaatatga tgaccaaaag ctgttccgaa aattgatgct tgatattaat
     8281 caagccggat tgagctggca gacgatttta aataaaagtg aagcattcga tgaagcatat
     8341 gatcgattcg atatcaaaaa agtcgcaaat tatggagaaa caaaaatcag tgaactaatg
     8401 gaaaacaaag gaattattcg taaccgaaga aaaatcgaag cagccgtcca aaacgccaaa
     8461 gcagtcttga aaattcaaga agaaatcggc agtttttcag agtatctttg gtcgttttct
     8521 aatggaaaaa tcgttgattc ttcttatcat tcacaagaag aagtcccaac aacaagtcct
     8581 ctttcagatg aattagcaaa agatctaaag aaaagaggat ttaaatttat cggaagcaca
     8641 acaatctatg cttttttaga agctgtcggg atcatcaatg atcaccttga cagttgtttc
     8701 cgcaaagaag aggtcgtacg tatcggcaga aagggcgaat aaagcatgcg aaaaatcata
     8761 ttttatggtg ctataagttt agatggctat ttggcaacga aaacggatga tcttcaatgg
     8821 ctttttgaca ctccaacagg taagcaaact acttatgaag ctttttatga aacaatcgat
     8881 acgaccatca tgggcagaaa aacttatcag gaagcaaaaa aatatttgga gaccgaagca
     8941 atttatccag agaaaaagaa tttcgttttt tccacccacg cacaattaca attgccagat
     9001 gctgaggtcg taaacgaaga tcctgttgct tttctaaaaa atctacaaat gacagaagga
     9061 aaagatatct gggttgtggg tggcggtcga ttgatcaaac cgctattgga acatcaaatg
     9121 attgatgaat ggtatatcca gattacccct gtattattag gggacgggat tcctttattc
     9181 caaaaaggaa catatgaagc gcgttttgaa atgctagaca cgacacgatt cggtgaattt
     9241 atcgaattgc attatgtacg aaagtagaag taaataaaat aaaaaaggca actatatgca
     9301 gaaatgtcct gtacatagtt gcctttttta ttaccgttat gctttttact ctgttaattt
     9361 gttagaaaaa tctagatacg catctaaaat cgtttggaag aaacttaatg ttccttcaac
     9421 gatattacca ttttcatcaa ttagattcgc aacgtttccg atatatgctt ccggttgctg
     9481 caaggttggc acattcaaaa agacaagtga ttggcgtaga tggtggtttg cgccaaagcc
     9541 gccgatccca cctggtgatg cagtaacgac taaacctggt ttatgatccc aaacactgtg
     9601 tccataaggt cttgagccta catctaaagc atttttcaat actgctggca cagaacggtt
     9661 gtattcagga gtaacgaaaa cgacaccgtc tagtcccctc acttcctcac gaaaacgagt
     9721 ccattcagca ggagcctgtt ctggagtttc gagatcctca ttgtaaaatg gcagatcatc
     9781 gatttttaca aatacacttt cgtacccttc aggaagcaat ttcgcaaaag cttctgctac
     9841 ttttttgttg taagaatctt ttcttaaact accaataaaa aatccaattt tttttgtcat
     9901 acgatttttc ctccttcaaa ctatctataa taatcttaca aaagataagt aactggagca
     9961 aataaaaaca cttactgaca aaagctacat agaagataga ttacttattt ttaacaaaaa
    10021 agaagtctaa aatcttctat tttctaaaaa aaatcgaatt taatcaagct gtaaagaaaa
    10081 aaagctttac agggtaaaaa aaaactgtta cactacatct tgtgaataaa acaatggagg
    10141 tggaaataaa taatggcagt taaaatccgt ttaaaacgta tgggttctaa aaagagtccg
    10201 ttttaccgta tcgtcgtagc tgattcacgt tctcctcgtg atggacgttt catcgaaact
    10261 gtaggtactt acaatccttt gaaagaccct gcagaagtag ttttaaaaga agacttagtt
    10321 cttgactggt tatcaaaagg tgcacaacct tctgacactg tacgtaacat cctttcaaaa
    10381 gaaggcgtta tgcaaaaaca ccacgaagct aaattctcaa agaaataagg tgaccggata
    10441 tgaaagattt aagcgactta gtcttaacaa tcgttcgtcc gctagtcact tatcctgatc
    10501 aagtcaagtt agacgtcgta gagtcgaaag acttttacga gtacaatcta acagtggctc
    10561 ctgaagatat tggccgtatc attggaaaac aagggcgtgt tgctaaagca atccgcacaa
    10621 tcgtttacgg tgttcggatc aatgcaccga aaaaagtgcg tttgaatatc atcgatgata
    10681 aggaaaagta aataaacgtg ctgtactcga attttcgagt gcagcttttt tgtttttttt
    10741 attaattgaa gaaatgatta tttggcaaaa caagcaagaa agcgtatcct tataggagga
    10801 gggagtgaac agccaatgag aaagaaaatg ttatttattc catttgctct attgttaagc
    10861 gcttgtagtt cggttactca agaatcagac aatacacatc tatcaagcag tatatctgaa
    10921 actgttacca gtccagaaaa aagtagtacc aaaacggctt ccaccactga acaaacaatg
    10981 gctacctcaa ataatgagaa aaagactgct ttagaccagt tgaaagaaca acagccaaat
    11041 gttcccatgc ctctagatgt accagtctct tcaggctatc tcaatatcgc agcgacacat
    11101 acaaagcaag gttattctat tttatattac agaacagatc gtcccctcgg gttgaatgct
    11161 gacgaattga atcaagaaac gcctattgca acctatctat atcaatatgg gtttgcttct
    11221 agtcaagaaa caatccaagt tttgcagcca tttgagatcg acacaaatgg tcagcaagtg
    11281 gacttaggtt ctcgaatcac agggtatcag caaggtgcag caggttcaag ttttcttgaa
    11341 tggcaagaag gaaactggcg tattcgaatc cgtgggaata atatagaagg ccaagatccc
    11401 ttactattag ctaaagaaat cgtagcttat ttggaagaaa acagtctacc agcacctgaa
    11461 caatttggta aaattactgt tgatatgggt gatacgacga atcgagccgt agaagtaagc
    11521 tggcaagaac cgaaaaatgc ctatacgatc actcatcaag atcctatgtc tgcgttgaag
    11581 atggcagttt ctatgaagag gttgtgaaat cagcgcgctg atctgagccc atcatttaac
    11641 tccaagtcac aggaagtaat caaaaatagc acgccgcatt tttgcataat tttggcttaa
    11701 taccttaaaa gaaaactaga attgcctctt cacacatgct aaaataaaac agacaaaaaa
    11761 gaaatgggga tataagttga ctgaatactt gaatgtagga aaaatcgtaa acacacaagg
    11821 tatcaaaggc gaagtccgtg ttatctcaac aacggatttc ccagaagaac gttacaaaaa
    11881 aggaacggtg ctaacactat tccaagacgg aaaagcacct gtggaattaa cagtcaaaag
    11941 tcatcgcaaa cataaaaatt ttgacttatt gagttttgaa ggacatcctt ctatcaatga
    12001 tgtggaaaaa tatcgggatg gcatattaaa agtgtcaaaa gacaactctg tagatctagc
    12061 tgaaaatgaa ttctattacc atgagatcat cggtctgcat gtattagaag atggaactga
    12121 gttaggtaaa gtaaaagaaa tcttgtcacc aggtgccaat gatgtttggg tcgttcaacg
    12181 tccgaaaaaa gctgatatat tgcttccata tatcgcttct gtcgtcaaag aagtcgattt
    12241 agaagctgga gtggtccgtg tagaaattcc agaaggactg attgacgatg aagattgatg
    12301 tattgacttt atttccaaga atgtttgaag gtcctatggg ggaatccatc atcggtaagg
    12361 ctgtagataa aggattatta gatatcaata tctctaactt ccgcgattat tcagataaca
    12421 aacatcagac agtagatgat tatccatacg gcggtggagc aggtatgctg ctcaaagtcc
    12481 agcccatcta tgataacatc caagccattg aaaaagctgc accggatgtc aaaaaaagag
    12541 taattcttct tgacccagct ggtaaacgat tcgatcagaa aatggcagaa gaattttcac
    12601 aagaagaaca cttagtattc atttgtggtc attatgaggg atatgatgaa cgtatccgca
    12661 cattagtgac agatgaagtt tccttaggag attatgtcct tactggggga gaattaggtg
    12721 cgatggtcat gatcgatgca acagttcggc ttttgccaga tgtgttaggg aatcagactt
    12781 cagctcaaac ggattcttat tcaaccggtt tattggaaca tccccaatat actcgcccgg
    12841 cagaatataa agggatgaaa gtaccagaag tattgacaaa tggaaatcat aaattgattg
    12901 aagaatggca attaaaagaa tcactaagaa ggacctatca acgtcggcct gatcttttgg
    12961 aaacacttga atggacacct caaatgacga aatttttaga agaaatcaag aaagaagaac
    13021 aagaaaaaac agcagatgaa gccaagtgac tttttctaaa atcttcttta cagtaggttg
    13081 ataatatgtt agtattttat ggtgagtgca aaagcactta actattacga tattccgctg
    13141 tgagaaaagc tcataagaat atttggaata aggagaagaa aaccatgaat ccattaatcg
    13201 aagaattaac aaaagaacaa ttacgttctg acatcccagc gttccgccct ggtgacactg
    13261 tgcgtgttca cgcaaaagtt gttgaaggta ctcgtgaacg tatccagtta tttgaaggtg
    13321 ttgttatcaa acgccgcggt gctggaatca gcgaaactta tacagtacgt aaagtttcta
    13381 acggagtggg cgttgaacgt acattcccat tgcatacacc acgtgttgca aaaatcgaag
    13441 tagttcgcta cggtaaagta cgtcgtgcaa aattgtacta cctacgtgca ttacacggaa
    13501 aagctgctcg tatcaaagaa atcagaagat aaacacggaa aacttccttg gaaatctgaa
    13561 atttgtgaaa agtccttgta tatcaagggc tttttctttt ttctctatca cagttttaag
    13621 ccatttttgg ctgttttgga ccatttttca atcatattcc cttaaaaatt gtcctagatt
    13681 gtccgacatt gactatcagt gtcgtcaaaa tagggcaaaa tttagtagtc agcttgacga
    13741 caaatataat acgaaaaata ccaaaacatt taccgaattt agcaactttt gaacccaagt
    13801 ttctcaaagg gtcagctatt agcaaaaaag acaaaacatg tacttttcta ctaaaaagtt
    13861 gatgtgatag gcttctatct aaataactat taggagtttt tatcgtgaag caaaatgatg
    13921 gacgtatcat ttggaaaaat caaagtgagt taaaactgat tttaacaatt aatgaattca
    13981 tcgaaaaaca cggaattaca tctagccgtc aataccagaa aaagctatca gaaaatccaa
    14041 attctgcacc aagtatgtgg ttcattaaca aaaaatatgg atcatgggag aatttattga
    14101 ttagtatagg acgagaaaat actgggtatg gaaaatgggc tagaatgtca gaacaagaat
    14161 tattggaaat agtagaagcc tttattaagt gcgagaagat aacctctcaa cgaatgtacg
    14221 aacaaaaatc agtagggaag aatattcctt cacttagtac cattaaaaag atgttaggag
    14281 atatacgtcc actttttaaa gaaaaaaatg atggatctcg atttactgat ttcgaactgc
    14341 tgttagaact aaaaaatgaa ataatccgat taaaactaca ggatgattta tcaatgacaa
    14401 agtttcgaaa actagttcaa tccccaaaac taccatcagt tgatacaatt atgaaaagaa
    14461 cgaacaaaaa ttgggaggaa ttgatggcag agattggatt tgattatcga agaatcaaaa
    14521 tttataagca gagaaacaac ctatccaaga caaagaaaac taaatagtat cactctaaat
    14581 cagacgttca aaattaaaat ttggacgtct tttttattac ccaaaaacga aaggagattt
    14641 attttatgaa aaagccaaga tttaagaatt ggcgtttgct cgcaacactg agtctattat
    14701 gccaaacaat tggtggatcg cttggcccaa cgattgcctt tgctgatgaa attactcatc
    14761 cacaaacggt aactgtggaa ttggatttgg ctcaccagta tgctgtcgaa ggtacattta
    14821 gcgatggtcg tcccatgtca gaagttaccg ttccgcacta tgcagtttac aatggtgtga
    14881 agcaagatat tttctgtatt gagccagggg tgccgattta caatgagttc actcctggtt
    14941 atgagaaaaa tccattgcct gatatgtcgg agaaagcgaa attagtttcc gttttatgga
    15001 aggaagctgg tacggatgtg gatacacata ttgtggccca gaagatgatt tggcaagaag
    15061 ttaatggcta cacgcttcac tcaattaaac gttctgatgg tagtgcagta aatatcgcag
    15121 ccattgagtc aaaaatcaat caagccattg cggattatca aaagaaacca agcttccata
    15181 actccacagt gaaaaccgtg ttaggtcaat cgactactgt gacagatacg aacggcttga
    15241 atttatcgga gtttgatgaa gttgtcgaga atatcgcaaa tattgattat cgtgtgaacg
    15301 gcaatcaact agtgattact ccaaatgcca attcaaaaga gagtggtgaa ttaaccctaa
    15361 agaagtcagc taatacagga acaccggtag cttataaaat ggctggtcaa caaactttga
    15421 tggcgggggc aattgataag cccaatacct acacaatcaa aattgatgtg gaaactgagg
    15481 gttctttgaa gattaaaaaa gtcgataaag aaacaggaaa tgttgtaccg ggaaccgttt
    15541 tccatttaga ctttggaaaa acattacctg caaaagacgt gaccaccgat aaagaaggca
    15601 ttgcgacatt ggatgagatt cctcatggcg cgaaagtaac cattactgaa aaatcagtgc
    15661 cagctcctta tacgattgac actacaccaa tcaccgcaac cattaaatct ggtgagacta
    15721 tttctgtgac ttcaaaaaat actcgcgaaa aaggtcaaat cattttgaat aaaatggggg
    15781 tggaaacagg aactgatctt tggaacgaca aatactcatt agccggaaat acgtttgcca
    15841 ttcgcaaaga cagtccaacc ggtgaaattg tccaagaaat gaccacggat gaaaaaggtc
    15901 atgcggaaac accaaaagag attgccaatg cgttggaatt gggaacctat tatgtgaccg
    15961 aaaccaaagc tagtaatggc tttgtgaata cctttaaacc agtaaaagtc gaattgaact
    16021 atgtcaatca aaccgtggct cttgttacca gtaacgtaaa agggcaaaac caagaaatca
    16081 ctggtgaaac cactttgaca aaagaagaca aagataccgg taatgaaact caaggtaaag
    16141 ctgagtttaa aggagctgaa tatactctct ttactgcaaa agatggtcaa gcggtcaaat
    16201 ggagtgaggc ttttaaacca gagttagtga agggaacgaa agcttctgat gaaacggtga
    16261 ctttgacttt agatgaaaag aatcaagttg ctgttaaaca cttagcgatt aatgagtatt
    16321 actggcaaga aaccaaagca cctgaaggat ataccttgga tgaaacaaag taccctgttt
    16381 ccatcaaaaa ggtggatgat aacgaaaaaa atgccgtgat tacccgagat gttacggcaa
    16441 aagaacaagt cattcgcttt ggctttgatt tctttaaatt tgctggatca gctgctggga
    16501 ctgccgaaac tggcttcaat gatctgacct ttaaagtatc gccattggaa ggaaccagtg
    16561 agattacagg tgccgaagat gaagcaatta cagcttataa cgagcaacta ggttttgatg
    16621 gctatggcaa gtttgaaaat cttccttatg gggattattt acttgaagaa gtagaggctc
    16681 cagaaggatt tcaaaaaatt acgccattag aaatccgttc tacttttaaa gaaaataaag
    16741 cggattacac taagagtgaa tacattttta cgattaccga aaaaggacaa aaacaaccaa
    16801 ttaaaacggt gaccgttcct tacgagaaac tgacgaataa agcattttct gttagcttga
    16861 atcgtttgat gctctatgat ttacctgaag aagaagatag cttaacttct cttgggactt
    16921 ggaaagacgg aggcaaagaa ttgacagacc ttgattctac cgagctagtt gataaattga
    16981 gctataactt gcatgaaatc aaagaagact ggtatgtggt agcgcaagcc attgatgtgg
    17041 aagcgacaaa agctgcccaa gaaaaagatg aaaaagccaa accagtggta attgccgaaa
    17101 caaccgcaac gttggcgaat aaagagaaaa caggaacttg gaaaattttg cataaattaa
    17161 ccgcagaaca agttttggat aaaaccatcg tcttattcaa ctatgtgtat gaaaacaaga
    17221 aaccctatga agcaggtgat gatccagtag cgaaagatgc tagcttgaac aatcaagccc
    17281 aaactgtcaa ttgtacggtg gaacgccatg tttccatcca aacaaaagcc cacctagaag
    17341 atggttcgca aacctttact catggggatg tggtggatat gttcgatgat gtgtcgatta
    17401 cccatgatgt actggatggc tcaaaagaag cttttgaaac aattctgtat gcattacttc
    17461 cggataatac gaccaaagaa atttggaaat ctggcaaaat tgattatgaa gtgaatgaca
    17521 aagaattcac taaaaccgta cttgcggaaa aagtggacac aagtaaatat ccagaaggta
    17581 caagttttac cttcaaagaa attaactatg gcaaagacgg aaacatcaat gggaaacaca
    17641 atgaggatct aaaagaaaaa actcaaactt taacacctaa aaaagttccg acaacaccaa
    17701 gtgcaccaga acaaccggaa ataccaactg ttccaagtga ctctcaagaa tctagtccta
    17761 cagtaaagac attcccacaa acaggggaga aaaattctaa tgttctgctg tttattgggt
    17821 ttaccttgat ctttgcgact gctgggtatt atttctggaa tcgccgaaac taaggtgatg
    17881 tgatgaaaca actaaatagg aaaaaccaac gtgcgcgacc gcctcctaaa aaaagtggtc
    17941 gcgctatttt tgtatccaaa actaaaaatg aaaagaggaa aagaagatgg aattgaaatt
    18001 tgttgtgcca gatatggccg aaacctttgg aaagataagg tatgccggcg aaggcgaagt
    18061 tttaactgaa ggatatgggc ggaatactac agtaattggt cgtagttatc atttgtattc
    18121 cagtaagcaa cgagccgatg atattgaagt ggtggtagct gcggaagccg gcgaaaagga
    18181 ttttgatcaa gatcaaccac taaaagccgt gaatccccat ttggttgcca aaggctatga
    18241 gattgagaat cgtgggttta ccgactacgt gttgtatgtc gatgatttag tgaaagcata
    18301 ggaggaaaag aagatgagat taacagaagg tattgttgta gattcaggac taacgtttgg
    18361 gaaattacga ttttccgcat tacgccgaga agtacggaag caaaatgagg atggaacggt
    18421 tagtaacgag gtaaaagaac ggacttataa tttgaaatcc tctgcgcaag gtcgaatgat
    18481 ccaagttagt atcccagcaa atgtaccctt acgcgagttt gcctatgacg cagaggtaga
    18541 gttggtcaat ccaatcatgg atacggtcgc caattatgtt ttccgagaag gaactactgt
    18601 caattggttc attaaggccg atgatttagt cttgaaacga caaccagatc agggaaattc
    18661 tacaaaccaa aatgaaggaa agaaataggt gaagcgtatg gaaattaatg ttgaacatat
    18721 tttagattgt ctcgatcaat atggaaaagg tgagctaacg gaggaacaac tcactaaagc
    18781 attaacctat gatgaaaaaa tgtttctgat tatgcatcaa gggttactgg aagtaggtaa
    18841 cgatgccgaa gaagattttg atgtactgaa ttggttaggg gaagaagagt ccttctttat
    18901 ggttatcgaa gtaaatgaaa gtctatgtcg agaagccgaa accgtattgg aagaaattgg
    18961 tgtggaaatg ccggatgcca ttgaagtttt tttaaagcaa ctagtggaaa cgaaacaact
    19021 ccctatagca gtaaatgact agcataactg cttgaaattg gatcaatgaa atcctatgaa
    19081 gcttttttcg attggaggtg gaaaccataa aaatgtacaa agggcatcgt atacgggcag
    19141 gagatcagca cttggtttat cactttgttc ttggctggct actcgctctg ttcatcggtt
    19201 ggatgagcgt cttttatttt caagagctta gacaatttga tatttctaag ctatcacttt
    19261 ctactataga aatcgttcgt tctataaaag atttaatcta tttgctagga agtctcgttc
    19321 tttcaggaag cacgatgttg ctttatatac acttttttca ggatcattgg cgcagtttgt
    19381 ggcatcgaca aaagctagcc cggatgattc tagaaaatca ttggtacgaa gtaaaacaaa
    19441 ctcagagtga aggatttttc aaagacctca atagtagtcg aaccaaagag acaatcagtt
    19501 acttccccaa aatctattac cgtatgaagg atggtttact ttctattcgc gttcaaattt
    19561 cactgggaaa atatcaagat cagcttttaa agctggaaaa gaagttagaa agtggtctat
    19621 attgtgaact agtagaaaag gaactcaaag actcctatgt ggagtacact ttactgtatg
    19681 atataattgc caatcgaatt gggatagacg aagtagtggc agaaagtggg gctttgcgat
    19741 tgatgaaaaa tcaagtatgg gcttatgatt ctttacctca tatgttaatc gctggcggca
    19801 caggtggtgg gaagacttac tttttactca ctatcatcga ggctttatta aaatctgatg
    19861 ccgagctttt tgttcttgat cccaaaaatg cggacttagc cgatttaggt acggtaatgc
    19921 ctcatgtcta ttcccaaaag gaggaaattt ctgcttgtgt ggaagatttc tatgagcgca
    19981 tgatgactcg tagcaaggca atgaaagaaa tgcccaacta caaaacagga gagaattatg
    20041 cgtttcttgg acttccacca aactttttaa tctttgatga atacgtggtt tatatggaaa
    20101 tgttaacgac gaaggaaagt gcggtgattt tgaataagct caaacaaatc gtgatgttag
    20161 gtcgtcaatc tggtttcttt ctgattctag cttgtcaaag accggatgcg aaatatttag
    20221 gagacgggat tcgcgatcaa tgtgcgacat gtttctaact gaaaaggtta ggcacttaaa
    20281 agaagaaaac ataagtttcc ttttaaggag aactgatatt ttgagcagtg gaatgatggg
    20341 gtaacgccct gaaacgctcc cttaatactc cgactggctg tttaacatat agctgttaga
    20401 tggtcagaag ctcggtgaag tcggctgaaa gttaccgtaa atatgataaa ttcatatacg
    20461 aaagttgttc agaggtgaat gatgtaacct ataggtcgga ggtctataaa atactcacgg
    20521 tgagaatgta agtaatacta ctgacgaact tgcgaatgaa agaatctata cacggactgt
    20581 atagaaatgt acaggattct accgtatcaa cggaacagaa tgtatgttgt ggtttagtaa
    20641 gattattggt tatgaacaac catgcaatgt tacaggcatt ggaaatatac aggttcaaag
    20701 caagcaccta aaagtatata taaagataaa aatatcgaaa catgggaagc tggcaatgtg
    20761 gaggaaacta tattccattg aaacatttgt gacgaagaat aataagcaca tttatgccag
    20821 tgaaagtggt ggcacagtac caatgaggat atagaaatat atcggaggaa tagccactag
    20881 tcaaaagaaa tcgttaatta aatgatgtat ttcatagaat cgagtaagac aaaataaaca
    20941 ctacaaccta agtaaacaaa ggtagtggtg ctatgaataa agtaaaaaca aataaaacac
    21001 ttcgtcatag tgaatactat ggcatgacac aaatatttga tgaactgtat gtaaaaagtg
    21061 ataaaaaaga agtttttaca gagctcatga caattattat gagtgatgaa aatattcgac
    21121 tagcatacag aaatatcaag aataacaagg gcagttatac agcgagtacc gataagaaaa
    21181 gtattcgaga cattaaaaca ctgtcagaag atacctttct aactgaggtt aaagttcttt
    21241 ttcgctgtta caaaccacga gcagttagac gtgtagaaat tcccaaacca aatggaaaaa
    21301 cacgccctct gggcattcca tcaatctggg ataggttaat acaacagtgt attttacaag
    21361 tcttagaacc gatatgcgaa gctaaatttc acaattatag ttatggattt cgaccaaacc
    21421 gttccacaca tcatgcgatt gctacctgca atcgactggc aaataggggg aagctacact
    21481 ttgtagtaga tgttgatatt aaaggattct ttgataatgt caatcactct aaacttttgc
    21541 gtcaaatgtg gacgattgga atccgtgata aatggctatt aggtattatt cgatccatgc
    21601 taaatgctcc tatagtccta ccaaccggta aagtcgaaca ccctaaaaaa ggtgtacctc
    21661 aaggtggtgt cctatcccct ttactatcta atatcatatt gaatgaatta gattggtggg
    21721 ttgcttcaca atggcaaaat accacgattg agacagaaaa gattatggat aggcgagata
    21781 aaggcaaagg cattgataag actaatcagt atcgggcatt aagacgaaca aacttaaaag
    21841 aaatatacat tgttcggtat gctgacgact tcaaaatctt ttgtagaaaa cgaagtcatg
    21901 cagataaaat atttcacgca acgaaaatgt ggcttaaaga acggttatca cttgaaatta
    21961 gcgaagaaaa atccaaaatt gtcaatctca aaaaaggtaa atcagaatat ctaggatttg
    22021 aattaaagct aatcaagaaa ggtaaaaaat acgtagtcga aagtcatatg agcaaaaaat
    22081 caatgacaag agttaaaatc caattaaaga aacaattacg taaagttgcc agaccgaaga
    22141 atcattgcga acaagcaaaa gaaattggat tatataattc tatggtgatt ggaatccatc
    22201 aatattatgg aattgcaacc tgtgtaaatc tcgattgcag taaaatagcc tatacactaa
    22261 aaccgttcat caatcacaaa ctgccgacaa agaaacatgg aaagatatta aatacattta
    22321 tcaaatcgaa gtatggaaaa agtaaagaaa tgcgatggtt gaataatgtg ccaattgtac
    22381 cgctcaacta tgttcagttt agacttgctg tccccctatc agagggaact tgcaagtaca
    22441 ctgaaagtgg acgaagcaag atacacagta aattaaaatt agacctagcc cttttacttc
    22501 acatgatgag aaatagtaat tatgaaagaa gtattgaatt tgtggataac agaatatcta
    22561 aatattctgc tcaaaaggga aaatgtgcta tcacgggtaa atttctcgaa tacgaagaaa
    22621 tccattgcca ccatatcgta ccagtaaaac aacagggtac agacaaatac agcaacctca
    22681 ttattattca caaaaatgtt cacgcattag tccatgctat cgaagaaaaa atcatacaca
    22741 aatacctgaa tgtattaaat ctaaccaatg aacaaataga aaaactaaat gaattacgtg
    22801 tcaaagctgg taatagtgtt ttaacagttt aacttgaaaa atatatcata cttaacattc
    22861 ttttgatgga acgccgtatg aagtgaaagt ttcatgtacg gtgtgaagcg ggggaaaatc
    22921 tggagatgac atcaaaggat tacctatcgc tatttaattt ccgggtggct ttgggtcgta
    22981 tgagtgaact gggatattcc atgatgtttg gcgaggttga taaaaaattc tttatgaagc
    23041 gtatcaaagg tcgaggctat gtagatacgg gagggagtgt gattagtgag ttttatacgc
    23101 cacttgtacc aaaaggatat gatttcttaa gggaaattag cgacattggt ggattaaacg
    23161 ttaatacgga aggataaaat aatagtatgt agcctaggag tgtcaagaat cctgggcttt
    23221 ttttacgagg tgatttatga catttttaga tttattcgct gggattggtg gcttttgctt
    23281 aggtatggaa caagcgggtc accagtgtat cggcttttgt gaaattgatg attttgctcg
    23341 ccagagttat aaggcaatcc atgatacaag taaggaggtg gaaatgcatg acatcacaag
    23401 tgtatcagac gagtttattc aatctctcgg accagtggat atcctttgcg gtggatttcc
    23461 gtgccaagct ttttcaattg cgggaaagcg gcaaggattt tccgatactc gaggtacttt
    23521 attctttgaa atcgctcggt tcgccgctat tctccaacct aagtttttat tccttgagaa
    23581 cgtccgggga ttactcaatc acgaaggagg ggctacgttc gagacgatcc tccgaacgct
    23641 ggatggattg gggtatgatg tggaatggca agtgcttaac tcaaaggcct acgttcccca
    23701 aaaccgtgag cggatcttcc ttatcggaca ttctcgagac gcatgtaccg aacaagtatt
    23761 tcctatcatt ggatcgtctc caacatctga tcaaaacatc agaaacttat taaatatcaa
    23821 cccttccaat cgaggaatgg ggggacaagt ctatgggtca gatgacgtag cgcctacctt
    23881 gaccggtgat gaaggaatca aaatcgcatt gccggtagat gatggaattt ctgtagcggg
    23941 tatgttactg ggaaattttg aacaaggcaa tcgggtttat gagataactg gaacagcgcc
    24001 tactttgtca acgaaacaag gcggaacgaa gatcatgctt cggaaaaacg aaacagaata
    24061 tcaagaggtg aagccaggga acagtgtgaa cctggctttt cctaattcca caagtcgtcg
    24121 aggccgtctg ggaaaacaaa gtgtgcatac cttattaaca ggagaccaac aagcagtcgt
    24181 cacggatcag tatcaaattc gaaagttaac acctagggag tgctggcggc ttcagggctt
    24241 tccggactgg gcttttgatc gagcttctca agtcaattca gatagtcagt tgtataagca
    24301 ggctggaaat tctgtaacag ttccggtcat ttttgatatt gctagaagat taaaggaggt
    24361 aaaaacagat gatttatgat gagttgattg gggaatctac tgggtgattg gcaagattca
    24421 gtcagatccg gaattggaag aagaactgta ccggctcaat tttgatattc gcaaaaacgg
    24481 ggtgaaagtc cctgatgatc cgtatgtaat tgatgaggaa acggatgctc gaatggagct
    24541 gaatcaagtc atcagtgaat tggaacgaat tgcggacttt gctaaagaac ctgatatccg
    24601 ccaatacttg tttgagataa aagcagagtt ggaaattgag ggtattaccg cggagtaacg
    24661 gccaaataaa ccactgatag gcactgaccg cgggggattt gcgaagcaga aatcctccgt
    24721 ggtgctgtgc ctgtttatgg acggcgttag ccggccatga tgtctcaccc cccgtatcta
    24781 acaggggggt acaaaaacac aaaaaataag caagcaacga taaggaatgg ctgtcctatc
    24841 aaggataata agcaatttgt gtagatgtta actgatttga aaaagttaac accttaaatt
    24901 tggaggtgag aacttggcac aaaggaattt agattatcgg ctattaaaag accggcgtaa
    24961 tgaatatggc gtttcacaaa ataaattagc tacgacttgt ggacttagtc gcccgtactt
    25021 aaatcagata gaaaatggtg gcgtaaccgc atcgacaaaa accatgagga aaatttttga
    25081 ccaactggaa agtttcaatc ccgagttacc tttaacgtta ctgtttgact atgtaaggat
    25141 tcgctttccc acaacggatg cgaggaaaat cattcaagag attctccatt tgaaatttga
    25201 ttatatgctc cacgaagatt acgcctttta ctcctatcaa gaacaatatg ttatgggaga
    25261 tattgtggtg atgttgtcac atgaagaaga taaaggcgtc cttttagaat taaagggtcg
    25321 tggttgtcgg cagtttgaaa cttttttact cgcccaaaag cgtagctggt atgacttttt
    25381 cgaagattgt ctaaaagccg gtggcgtgat gaaacgctta gacctggcaa tcaatgatcg
    25441 agttggcctg ttagatattc ctgatttaac gaaaaaatgt cagaaggaag aatgtatctc
    25501 cttgtttcgt accttcaaaa gctatcgttc cggggaactg ttgaaacctg atgataaaga
    25561 tggtatgggc aatactttgt atattggcag tcttaagagt gaggtctatt tctgtttgta
    25621 cgaaaaagac tatgagcaat atatcaagtt agggattcct ttagaccaga ccgaaacgaa
    25681 aaatcgtttt gaaatccgac tgaaaaatga tcgagcttat catgcaattc aagatttgtt
    25741 aaaaggtcgc ag
//
LOCUS       DACCVZ010000037        25263 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.037, whole genome shotgun sequence.
ACCESSION   DACCVZ010000037 DACCVZ010000000
VERSION     DACCVZ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.037"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..210)
                     /locus_tag="IVW63_001526"
     CDS             complement(<1..210)
                     /locus_tag="IVW63_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP7859806.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
     gene            complement(309..623)
                     /locus_tag="IVW63_001527"
     CDS             complement(309..623)
                     /locus_tag="IVW63_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859807.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(691..1185)
                     /locus_tag="IVW63_001528"
     CDS             complement(691..1185)
                     /locus_tag="IVW63_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859808.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            complement(1178..1492)
                     /locus_tag="IVW63_001529"
     CDS             complement(1178..1492)
                     /locus_tag="IVW63_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859809.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            complement(1708..3099)
                     /locus_tag="IVW63_001530"
     CDS             complement(1708..3099)
                     /locus_tag="IVW63_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP7859810.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            complement(3084..3695)
                     /gene="mobC"
                     /locus_tag="IVW63_001531"
     CDS             complement(3084..3695)
                     /gene="mobC"
                     /locus_tag="IVW63_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HAP7859811.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            complement(3699..3896)
                     /locus_tag="IVW63_001532"
     CDS             complement(3699..3896)
                     /locus_tag="IVW63_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859812.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            complement(3887..6565)
                     /locus_tag="IVW63_001533"
     CDS             complement(3887..6565)
                     /locus_tag="IVW63_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859813.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            complement(6552..6770)
                     /locus_tag="IVW63_001534"
     CDS             complement(6552..6770)
                     /locus_tag="IVW63_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859814.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            complement(6846..7898)
                     /locus_tag="IVW63_001535"
     CDS             complement(6846..7898)
                     /locus_tag="IVW63_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAP7859815.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            complement(8051..8377)
                     /locus_tag="IVW63_001536"
     CDS             complement(8051..8377)
                     /locus_tag="IVW63_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859816.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            complement(8389..8589)
                     /locus_tag="IVW63_001537"
     CDS             complement(8389..8589)
                     /locus_tag="IVW63_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7859817.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            8664..9314
                     /locus_tag="IVW63_001538"
     CDS             8664..9314
                     /locus_tag="IVW63_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7859818.1"
                     /translation="MSIKILLNLWFSCYNSLEFTIGGVTLNRIKFYIDSSKKTIKQIS
                     TETGINYTTLTNYYRGERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIK
                     TARLEKKDKIVKNIASLDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSF
                     EYTILFAKQKKFINKALNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            9369..10535
                     /locus_tag="IVW63_001539"
     CDS             9369..10535
                     /locus_tag="IVW63_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7859819.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            10952..14179
                     /gene="fss3"
                     /locus_tag="IVW63_001540"
     CDS             10952..14179
                     /gene="fss3"
                     /locus_tag="IVW63_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAP7859820.1"
                     /translation="MYKKQKKKLCVLTILSLAVQSIVGAIAPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCVEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIADYQKKPSFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENTANIDYRVN
                     GNQLIISPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTVKIDVE
                     MEGSLKIKKVDKESGDIIPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTATIKAGETISVTSKNTREKGQIILDKTGIETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGHETQGKAEFKRAEYTL
                     FTVKDGKAVKWTENFKPELLKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDSEKNAVITRDVAAKEQVIRFGFDFFKFAGSTTGTAETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDYTKSDYIFTITEKGQKQPIKTVTVPYGNLTNENFSVSLNR
                     LMLYDLPEEEDSLTSLATWKEGDKELTTLDSTELVDKLSYNLHEIKEDWYIVAQAIDV
                     DATKAAQEKDKKAKPVAIAETTATLANKEKTGTWEILHKLTVEQVLDKTIVLFNYVYE
                     SKEAYEAGDEPVAKDASLNNQAQTVNCMVERHVSIQTKAHLEEGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALFPDGTSKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYDKDGNINGKHNEDLKEKSQTLTPKKVPTTPSTPEQSEMPTVP
                     SGSQESSPTVKAFPQTGEKTSNVLLFIGFSLIFATAGYYFWNRRN"
     gene            14291..14605
                     /locus_tag="IVW63_001541"
     CDS             14291..14605
                     /locus_tag="IVW63_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP7859821.1"
                     /translation="MELKFVVPDMVETFGKLTYGGEGEVLSEGYGRNTTIVGRSYHLF
                     SNKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLIAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            14618..14992
                     /locus_tag="IVW63_001542"
     CDS             14618..14992
                     /locus_tag="IVW63_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP7859822.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQLNQGKPTNQNEGKK"
     gene            15002..15346
                     /locus_tag="IVW63_001543"
     CDS             15002..15346
                     /locus_tag="IVW63_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAP7859823.1"
                     /translation="MEINVEHILDCLDQFGKGELTEEQLTNALTYDEKMFLIMHQGLL
                     EVGNDAKEDFDVLDWLGEEESFFMVVEVNESLCRQAESVLEEIDVEMPDAIERFLKQL
                     VETKQLPVVVND"
     gene            15415..16431
                     /locus_tag="IVW63_001544"
     CDS             15415..16431
                     /locus_tag="IVW63_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAP7859824.1"
                     /translation="MYKGHRIRAGDQHLIYHFVLGWLIFLFIGWMSVFYLQELRQFDI
                     SKVSFSTSEIGWSMKDVICLLGSLALSGSMMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQGEGFFKDLNSSWTKESISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LENKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIEEIVAENGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIQALLKSDAELFILDPKNADLADLGTIMPHVYSQK
                     EEISECVEDFYERMIARSRSMKEMPNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            17025..18899
                     /gene="ltrA"
                     /locus_tag="IVW63_001545"
     CDS             17025..18899
                     /gene="ltrA"
                     /locus_tag="IVW63_001545"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP7859825.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            19025..19381
                     /locus_tag="IVW63_001546"
     CDS             19025..19381
                     /locus_tag="IVW63_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAP7859826.1"
                     /translation="MILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRV
                     ALGRMSELGYSMMFGEVDKNFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREIS
                     NIVGLTVHTERENNSV"
     gene            19426..20568
                     /gene="dcm"
                     /locus_tag="IVW63_001547"
     CDS             19426..20568
                     /gene="dcm"
                     /locus_tag="IVW63_001547"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAP7859827.1"
                     /translation="MTFLDLFAGIGGFRLGMEQAGHQCIGFCEIDEFARRSYKAIHDT
                     RKEVEMHDITSVSDEFVRSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     ATLLQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQSRERI
                     FLIGHSRDACTEQVFPIIGSSSTSDQNIRNLVNINPSNRGMGGQVYGSDSVAPTLTGD
                     EGIKIALPVKDGISVAGMLSGNFEQGNRIYEVTGTAPTLSTKQGGTKIMIRKNETEYQ
                     EVKPGDSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKGVKAYDL"
     gene            20558..20847
                     /locus_tag="IVW63_001548"
                     /pseudo
     CDS             20558..20847
                     /locus_tag="IVW63_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395166.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21103..22287
                     /locus_tag="IVW63_001549"
     CDS             21103..22287
                     /locus_tag="IVW63_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP7859828.1"
                     /translation="MAQRNLDYRLLKERRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     IASTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVRKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYYAIQDLL
                     KGRSIESTTFSIINRYLRFADKVDGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     IV"
     gene            22302..22397
                     /locus_tag="IVW63_001550"
     CDS             22302..22397
                     /locus_tag="IVW63_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAP7859829.1"
                     /translation="MEIVKDMLLVLGGSMLGVTVMCLMNASAAAD"
     gene            23167..25077
                     /gene="ltrA"
                     /locus_tag="IVW63_001551"
     CDS             23167..25077
                     /gene="ltrA"
                     /locus_tag="IVW63_001551"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP7859830.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         8304 a         4412 c         4636 g         7911 t
ORIGIN      
        1 taaatcagat acataagccc atgtacccgt tcgttgtaaa taaagttctt cttgtaacaa
       61 ctcccatttt ctcttagaaa tcataatgac gccatcgttc aatccatttt tagaatccct
      121 agtaatttct atttcagaat ttgaatgaac tacttcttgc aacactttac ctatattttc
      181 tttgaagttt gttggagtaa tagtatccaa aatgaatacc tctcttctct atacctctat
      241 tatgaagtgc ccataaaata aagcaagcgt tgaggaataa ttctatcaac acttgcttta
      301 ttaagctttc attttgtagt ttgactaaaa ccaataatct tatttctaaa ctctcgaaaa
      361 acttcttgtg gttgataata gtctggatct atttcaaatg tttgtgagaa taattcattg
      421 aatttttcta ctgaaataat gattttacca ttcttctctc gactgttttc tattatttct
      481 gcttctaatt caaataaatc tagtgacgaa ctaaaatcat aaatcatgtc atattgaata
      541 aaaaaatcaa gaaaaagttg ctcaaactct tccttattta tcactaatgt ttcaaacgga
      601 acaactttat tttcctcagc cattctccca gttccatttt caaaaatcac aaaactgata
      661 ttaccttaaa aactactaac aaaataaaac ttataaagta aatggcaacc caactatgta
      721 accattctct ctacgtacta cgatttggta gtcctgcctt tcaatcggta attcataata
      781 gtaatttact gtttcttctt tgccactttc aatatactct ggattatcca atatcatatc
      841 atactcataa agttcttcac catccttatt ttcaatcgac cattgttgtg gacgtatcgg
      901 attttctgta tcatttataa gtgtataggt cacttgtaat acacgatcat gttgtgcaaa
      961 ttcatttctt ttttcggtca cttcaatatt tttaaatgtt agttcaaccc catctgcctg
     1021 ataagtttca cctattttta aatcttttgt tacaattttt attggctttt cttctggaaa
     1081 atgtctggct ttaattgtta gataacttcc aaaaagaatc aatcctagta gcactaaaag
     1141 aattccttta acgagccact gaaacgggaa gtaaacttta aacatctttt ttctcctccg
     1201 ttttgtattt gttttttaga gaatacgata acttttgatc aatgtcatcc agcttttcaa
     1261 ttacttcatt acttatcatt gattctagtt ctgaaatttt ttgttcaaat ttaatgcttt
     1321 caggatcatt aaatttatta tttgatggac tagctaacac tggtaaattt gaaaccataa
     1381 cacgaaacat atttgccttt gaaccaaaaa ttcctttgtt ttggttgtaa aaattgttga
     1441 atatttcttt agtttcttct gaagccgaga ctttaaaata tggatagttc atttttttct
     1501 tccacctttc tttttttggg agggagtctg tagggagctt gctccctcag agatttaccc
     1561 gccatctgac ttgccagaaa gtagcctagc gtgagcgggg cggattgact ggcaagtaga
     1621 tgggtagctg gcgtatgtcc taaaaactgc ttctttccaa gcaactcttc ataggcaaaa
     1681 aactggaaag tccactaaca agcccattca gaattccatt tcaaaatttt gttgcctttt
     1741 ttgctgattt tcaatcattt gttgtgtgaa ttcataatcc tttttagcac gatacatttt
     1801 tacatcgtca ttcattatgc gactgatttg atagtgaatc tgtttagcag aaggtgtatg
     1861 agaacaattt tcaaaaccct ttgccggtag aaataactct ttctgatcag tctttttaat
     1921 agaaattgtt ttacttttcg cactacgtaa agtttgagga ttcacatccg tatgaagttt
     1981 aatcgtgtat tcttgatcat cttctaaaga cattgtattt acaaaatgct tgtctacctc
     2041 tcgcaagaag tcatcatatt taatgaattt ttcatcgcct tcacggtcgc taaattgctt
     2101 ttgtgcgatg gaatctaatt ccacaaacgg tacatttaac tcaccagttt tgtaatttac
     2161 tccactaatt agcgacataa cttgctctct ttccatatta aaaaaatttt ttatatgtga
     2221 ttcttctaaa ttcttttcaa gttgttcaga aacagattca aatgaatatc ttttccctaa
     2281 ctttcttgca ctaaaagtac gttcgacata ctgacttttt tcttttctag attgtttatc
     2341 tcttcctaaa gtaattaact cacctctacg ctcatagaaa tttacacctt gtttgtaaag
     2401 aacatagcca agtttgttat ttgtttttga aaattgataa acttcaatgt tatattcttt
     2461 tgccaaatga tccgaaaaat cttcaaaaga attcacttcg catttttcca acgttgcttc
     2521 gatcgcattt tgcacaaact cttgataatt aatttttcca tatttcatct tagaaggatc
     2581 gtttgaataa agattggttc tcttttctaa gttttcatag tactcattat tcactgattc
     2641 aagaccatgt tcattgagga cttgatcgtt aatttttcgc attagttcta aatctttagg
     2701 gtcaatacgc aaccttttac atgtttccat gttaatatta ttaatgacaa gatgactatg
     2761 aaaatgatct ttatcattgt gacttgcaac aatgatttgc gaatttggaa aagctttctc
     2821 tgcaaattcg acagctattt cgtgcatttt atcaatactt aactctttag aagtactctt
     2881 atcaaacgaa tgaataacat gaaacgcttg tgctatatct ttagatttat tcatcttggt
     2941 acgtactaaa ttcatttctt gcagtgcttc ctcactatca tcactacaat ttattcctga
     3001 gactgcaaca catttttctt tttttgaagg attagctgca tattgtaata gcgaggataa
     3061 atttttcttg cgtcctttcg atgttatagt agctcccaaa gttgtttcac ctcatctttt
     3121 aaacttgcaa taatctgaat tgagtgaatt aaattccgat caactttttg ggaatactct
     3181 tctttcgtac ccggtctagt ttgcttttct atccaatatt cgaaatattc tttttctact
     3241 tctgataatt taaaaaaaga gggggcactc cgattggact ccaaaaaaat gtcatctgga
     3301 taactaatca tcaacttttt tgctatgcta ttcgcaagtt catctttaaa aatgttgtaa
     3361 cggctagcat caaaactaaa atgtaggctc ttttcttttt tatcttcaga ttcttctcta
     3421 aaatatttag caatgatatt taatgccttt accgcttgat tcaaattgtt accaatttga
     3481 tttaactgtt tggttaaaac taccctatca tcttcagcta acaacggcgg ttcatatttg
     3541 agtcccttta accgctcacg gcaaacgtct gctctagaaa ttcccctttg ttttgcaatc
     3601 aatgtcagtt caagataagt ctttttatcg acacgaaaat ttaaggcctc actatgtttg
     3661 cgattttttt cgtacatttt ttgtttatca tccattgatt atcccctcac atttttttct
     3721 agagagcaac atttgaaatt gctctctatt tcatttttca tctttaattc ttcttgaatc
     3781 atcagttcaa tataattagt gaccgtgatt ttttcatttg ttgcgttctt tactgattca
     3841 cataattcgt caagttctaa gaaatcatgc gtactaatct ttagaattaa ttgcatgaca
     3901 atccccccct tttatttctt aataaattat cgaaaagtgg attaggatca ttaagtgtat
     3961 ctctgaataa ctcattgtct tcataagtga atcttcgtct tgattttgat cccttatcat
     4021 tttcacggat ttcactatca ataatcactg tttcatgatt tgaatcaaat tttttcgctg
     4081 actttctgtc ttcaacgata ttgatttttt gtgttttttc tttcatttct ccactatctt
     4141 tttgaatgtt ctcccgaaca tctactgttt tgaatccttg actacttgta gaactttgta
     4201 cattttctcg gacatctact gtttttggtt gacttgcact gctaccttgc acattctctc
     4261 ggacatccac tgatttaaac ccttgactac ttgtagaatt ttgtacattt tctcgaacat
     4321 ctactgtttt tggttgactt gtactgctac tttgcagatt ttctcgaaca tcaattgtct
     4381 tagtaccttg agcatttgaa gaactttgta aattctctct tacatcaaca ttccgtccaa
     4441 catgaccatt cagtgaacct tgaatatttt ctcggacatc tactgatcgg ccaccatgac
     4501 tacttgtaga attttgtgga ttttctttga ctaatttttc taatcctgta tttgaatttt
     4561 tagcttcttg aattctttct ttggtcaacg cttcttttcc gtcaatatta gcgcctgtcc
     4621 gcccttctac acgtttcctt aacattattt cctcgcgatt cattgcttca ggcgtgtatt
     4681 tcgcttcatg acgcttctga ttaattaatt cttcagcaga cttagcttga ccgtgcatag
     4741 catttttacg ttcttcaata tcttgttgga ctttttgctg aattgcgctt gcaggattat
     4801 tattcgattc agcattattt ttcattgctt cacgcatacg ttcagaacta gacataattc
     4861 tatcggcatt ttcaacttta gcaccatctt ttctatctga aagacgtgtt ggcacggaat
     4921 cagcatattt tccagtttca tcttctttat ttttagctaa cataggtttg ctatttttat
     4981 taatagcgga cactgtacca tcatctaaac cttctttaaa cttattcttg gtatcattag
     5041 ctatatcacg catactctta aatggttttg ttgctctttc actagccatt gtagctccat
     5101 ctgaagctaa accggataat ccacgttcat gggcatatcc caaagctctt ccagttttgc
     5161 cagctttttt tgatagagtt tcgccgaaat tcttttctgg ttttcgatct tctccttctc
     5221 cgcttccttt agcacgatta aatccatttg atccttttct aaacagcatt gcgcccattc
     5281 caaaagcaga agcaagttgc ccatagcctt ctttgagtcc aatatcaaca ccaaagtatc
     5341 tcatgactgt tccactgcct ttgattaaaa caaaaacggc acagatataa gcaattgttt
     5401 ttataaaaat atttgttgag ataccttgtc ctgagttcag aaaattgata aacatagcaa
     5461 acattgataa cccaaatcct tgaaacccaa cagttaagta acattgtaga atatctgata
     5521 gaacaacttt tgaacgctgt cctgtctcaa tatctgttgc aaaaacaaga acacctaaca
     5581 cacgtttaaa tgcaagttct agtattgctg taatgatcac aaacgcgctg aacacatagg
     5641 cgattgctaa cgctgtcaac ccaattgaaa tcccccatag atttgcttgg tatcggtaat
     5701 agcctgattt caagctatca gaaaatgttg ataagaagtt gtcagaaaac tttgtagcaa
     5761 caaattcatt attagaattt tcaactaatt cataacgaag attgtccgca attggatttt
     5821 ctttttccaa tttatcaatc actttatccg ttaacacttg tgtgagatcc gtctgttgaa
     5881 aattttttcg tgttaaatta tttcgatcct ccgttttatc aatgcttgag tactgatctg
     5941 ttttattaat atatgctaaa tctgttactc cttgttttat caatgaccaa gcgactccgt
     6001 catctgaatt tgtaatcgta gtagagtcct tataaaatgt tttagcaaat tgaataccac
     6061 tagaaatcat ggttggcatt aaaagtatta atgctataga catcactacg ttcattccaa
     6121 ccgattttaa atccactgtt ccttttccag taatcatttt gtaaccaaca aacatcaatg
     6181 aaaggatcat taatccaatg acaattgtat ttacggctga ttgataaaca ttatttagcc
     6241 ctgtactttc aatgaaattg aacaaatcca gcacatctgg aatcatattt tgaatcgaat
     6301 ctgtcacagt aaacatgcct tttaccacag cccatccgag ccaaatcccg aactgactaa
     6361 ggaaatctcc attgtacttt tttaggtaag gtctataaag agaattattc aaaaactctg
     6421 tttgactttt tgtgtcatca aaccaattga aaatactcgc atgagcaata ttacttgtaa
     6481 aaataatcat agctatcaga acaagaaaat taacaaccaa ccaatttatt tttttattgg
     6541 caatcttttt ttcaattatt ttcatcgtta cctcccttag cccattttct gaggctctca
     6601 gagagcttct gagccatttt ttgattaatt atgacatgag ttacacaatt atcattttca
     6661 gctcttaaat cgagaactat agtgttgaag caaatagtct cgattaattc gagactatct
     6721 gtattttgat ctagacacca aacttgatct attaaacgat ttttaatcaa aataacccct
     6781 cctatattca aagttctcaa atgaagtgga gatacccctc catttcattt gactcaattc
     6841 tattcttatt gcttatctat tccttcgctg atttgcaatt caattagttc taacgcttta
     6901 ttttttagag aagcaaagat ataatcgtct ttttgtttga tacgatgatc tgtttttgct
     6961 cttcgtatca agtcacgtaa agtcattgat agctgttctc taacatgatc tacaaaatac
     7021 ttgttattac aaatttcata gataattttc agttgaattt tttgttcttt ttcagcagat
     7081 ctaatcgcat atttgaattt tttgtaccag ttgtcgaatt gacgataatc actattgcta
     7141 gccagtttta agcaattcac aatactttct ccccatattt gtttaagaag attttcttca
     7201 ataaatgttt cgatcaattc ttcatctaat ttattatttt tagttgaaag tgattcaaga
     7261 agatcatcat tatgtgattc tttaatatct ttactatctt tataagactt atataattct
     7321 agttcatttt ttgaactatc agcaaaattg tttttgtctc ttgttttcat tgatgtgtcg
     7381 catagttcaa attttgaact atcaacagaa tattgatttg ttccatagtt caaattttga
     7441 actatcaagt ttttttgtct attttcttga tgggttatct tattaatttt ataaacatca
     7501 tctttgcaca gaacaggctt taacaaataa taaaaatttg ggaacatttg cattttactt
     7561 ttattgaagc cattttttct tttcacaaga agtttaactt tttgaagttc atctagtgct
     7621 gataagattg tattttttga cattcccgaa atttctacga gatttttgat ttcaaatatc
     7681 aaaaaaattt tttgattctc atcatacaag ttatttttca atgaaagtct atttctatct
     7741 tttagtaaca tataaactaa cttagaactt agtttcattt tcttatattt ttcatttacg
     7801 tttaaaaaaa taggatattg atagtataat tctgcatata tatcagaatt agaatagcct
     7861 tgcttttcaa ctaagctttc aacttctttt tcattcattg tcacacctgc ttctgatttt
     7921 atttgctata atagattcaa ataaagtttt ctcagaactt tattattgag tgttcccccg
     7981 atctgcaaac tgacgggaac actcttttta attttttcta cttcatcaaa tttaaaaaac
     8041 gaggtgtttt ttaaatttga tgactcaata tccatttttt gcattcttct tttgaaaaca
     8101 actccatttt ttctaataaa ataactggca atcccattct tttaaatttc aaaaaagttg
     8161 tatatgatac attcaaatat ttagccatct cttttccttt tagaaatggt ctttctaatc
     8221 cggtatcaat tcttgcttga tcaatagcct cttttgtcat ttcaaaaaca taatttttca
     8281 attgattcgt ttgttgttta tctaacatta ctgtaattcc tgcatccatt atttttctcc
     8341 tctcattttc tatttcttca atcagccaac tcgccaagtt gtatttattt agattttcaa
     8401 atcattaagt aaccaattta ccaacttttg ataagtagat gctctaatac tttctttgct
     8461 cccattttcg attttgacat atgttttccg atttatacct atcaattttg ctgcatcgtt
     8521 tttagtaagt ataagatcgg ctctatgtct tcttaagctt ctaatgaatt gatcattaag
     8581 agttatcatt cagcgcctcc tttcaaatta ttcactttgt ggtttttatc ttaataagca
     8641 cattttaaac cacaaaacga gtaatatcaa ttaaaatatt actcaatttg tggttttcat
     8701 gctataatag tttggaattt actatagggg gcgttacttt gaatagaata aaattttata
     8761 ttgattccag taaaaagacc attaaacaaa ttagtacaga aactggtatt aactatacaa
     8821 ctcttacgaa ctattaccgt ggtgagcgaa atcctagaaa tactgaaaca tggaatatcc
     8881 ttgctgatta tttccatgtt cctgtaagtt atttgatggg attagacgaa acaaattcca
     8941 tagaacaacc taatcttgat agaataaaaa ctgctcgttt agaaaaaaag gacaaaatag
     9001 tcaagaatat tgccagtctt gactcagatt attttactga attatctaat ctatactttt
     9061 ccatgacttc tttacttgaa gtcaaacttc aagaagatga ctccgacttt ctttttttaa
     9121 aaagtattct agaggactcc tttgaataca cgattctatt tgccaaacaa aagaagttta
     9181 ttaataaagc tttaaactta aatatcgatg aaagaaaaga gttagaatct gagttatttg
     9241 gcaacttaac ccaagtacag gttaacaatc taaaaagaga gataacagct cgattaatat
     9301 caaaacttca ataaaactaa ttattcaatc agccaactcg ccaagttatc agattggaga
     9361 gattagttat gtcaatacaa aagtacacaa caaaaagcgg tgcacgatat agtgtccgct
     9421 tgtatgttcg taaagatgaa aatggaaagc aagaatacta tgtaaaaaaa gggtttaaaa
     9481 ctgaaaaaga agccaagtta cacgaagcaa gaaaaaaggt cgagattgaa gataccggct
     9541 atcataagcc ttctaatgac ttgtttataa cagtgtatga agaatggttg ccttcttata
     9601 ggaatcgtgt acaagaaacg acatatcaac gtacaaaaga ccttttccgc ttgcatatac
     9661 taccaaaatt cgggaataag tccatttcta agattactcc tgttcactgt cagaatgcag
     9721 tcaatgaatg ggctttaaaa ttcaagaata tcaaacagct taagtcttac agctctcaaa
     9781 tatttgagta tgccattttt gcagagctat tacaccgaaa tcctatggca aatacaaatc
     9841 taccaaagcg ggaaaagaaa gaaaatgaaa attacttttc attagaagaa ctaaaagctt
     9901 tttgggatat tctcaataaa gaagagcctt taaaacatat tttaatcttc cagcttttga
     9961 ttactactgg tatacgtaaa ggagagctag ctgctcttca ttggtctgac atttattttg
    10021 aagaacagct aatgtatgtt agaaagagct atgcaactat tcgaaatgaa gagaagaatg
    10081 caagaagaaa aactgtcagg attcaaaaaa atacaaaaaa tatatcttcc gaacgaatat
    10141 taccaattga tgcacaaact attgaaatgt taaaaatctg gaaaaaagaa caagctcgag
    10201 agcttttgca gtttggcata aatacaaata caaaaaatca acttatcttt acctatgtaa
    10261 atgcagacgg tgacattaat caacctttgc atgcggacta ttcaaataat atattgaaac
    10321 gtttagagaa gaaatataaa tttaagcacg ttactattca tggattccgg cacactcacg
    10381 ctactcttct actagaaggt ggagcaagta tcaaagaaac acaagatcga ttgggtcata
    10441 aaaatgctga aactaccctt aacacttatt ctcatgttac tgaaaaagct caacgaaatg
    10501 cgttagaaaa attcattgct tacactggtt tataatattg tcattacctt tctcattacc
    10561 agaacgaaaa aaagacacct tctcgcaatg agaaagtgtc tgaaatcgtt ggtataacaa
    10621 cgattaacgt tttgaaaact gtgaagcttt acgtgctttc ttaagacctg gttttttctt
    10681 cgtatcattg aataagtttg aaaagccttg atttataaag gtttttccgt aaatatattt
    10741 tgttatattt gattaaattt gaaatgtttg tgttctaaaa tgtgttctaa tttaaaggca
    10801 gtatatttcg tattttatat taaattttta ggctcattca ttctcaaatc cattctattt
    10861 agtcaataaa tattttaaaa agactttata aacaaagatg ttcaagcgag catcttattt
    10921 ttttgtgcct aatttgaaag gagaacattt catgtataaa aaacaaaaaa agaaattatg
    10981 tgtattaact attttgagtt tggctgttca atcaattgta ggagcaattg ctcctacgat
    11041 tgcttttgct gatgaaatta cccatccaca aacggtaacc gtagaactag atttagcaca
    11101 tcaatatgct gttgaaggaa cttttagtga tggtcgtcca atgtcagaag tcactgttcc
    11161 gcattatgca gtgtacaacg gcgttaaaca agatattttc tgtgttgaac caggagtccc
    11221 gatttacaat gagttcactc ctggatatga gaagaacccg ttaccagata tgtccgataa
    11281 agccaaatta gtttccgttt tatggaaaaa agtaggtaca gatgcagata ctcatattgt
    11341 ggcacagaag atgatctggc aagaagttaa tgggtatacc cttcactcaa taaaacgatc
    11401 agatggtagt gccgtaaata tcgcagccat tgaggcaaaa atcaatcaag ccattgccga
    11461 ttatcagaag aaaccaagct tccataatag tacggctaaa acagtattag ggcaatcgac
    11521 tactgtgacg gatacgaata atctgaattt gtcagagttc gatgaggttg tggaaaatac
    11581 cgcaaacatt gattatcgtg tgaatggcaa tcagttgata atcagcccaa atgccaattc
    11641 aaaagaaagt ggtgtgttga cgcttaagaa atctgctggt accggaacac ctgtcgccta
    11701 taaaaaggct ggccaacaga ctttaatggc cggggcgatc gataagccga acacttatac
    11761 ggtcaaaatt gatgtggaaa tggagggttc tttgaagatt aaaaaagttg ataaagaatc
    11821 gggtgatatt ataccaggaa cggttttcca tttagacttt ggaaaaactt tacccgcaaa
    11881 agacgtgacc accgataaag aaggcattgc gaccttagat gagattcctc atggtacaaa
    11941 ggtaaccatt actgaaaaat cggtgccggc gccttatacg attgatacca cacccatgac
    12001 tgccacaatt aaagcaggtg aaaccatttc agtgacttca aaaaatacgc gagaaaaagg
    12061 tcaaattatt ctggataaaa ccggaattga aacagggagt gatctttgga acgataatta
    12121 ctctttagcg ggcaatacgt ttgccattcg caaggatagc ccaactggtg aaatcgtcca
    12181 agaaatgacc acggatgaaa aaggtcatgc agaaacacca aaagagattg ccaatgcgtt
    12241 ggaattggga acctactatg tgactgaaac caaggctagt catggctttg tgaatacttt
    12301 caaaccagta aaagtcgaat tgaattatgt caatcaaaca gtggctcttg ttaccagtaa
    12361 cgtaaaaggg caaaaccaag aaattactgg tgaaaccact ttgacaaaag aagacaaaga
    12421 taccggtcat gaaactcaag ggaaagctga gtttaaaaga gctgaataca ccttgtttac
    12481 tgttaaggat ggaaaagcgg tcaaatggac cgagaacttt aaaccagaat tgttgaaggg
    12541 aacgaaagct tctgatgaaa ccgtaacttt gactttagat gaaaagaatc aagttgccgt
    12601 taaacactta gcgattaatg agtattactg gcaagaaacc aaagcgcctg aaggatatac
    12661 cttggatgaa acaaagtatc ctgtatccat caaaaaggtg gatgatagcg aaaaaaatgc
    12721 tgtgattact cgagatgttg cggcaaaaga acaagtgatt cgctttggct ttgatttctt
    12781 taaatttgct ggatcaacta ctggcactgc cgaaactggc ttcaatgatc taacctttaa
    12841 agtgtcgcca ttggaaggaa ccaatgaaat caccggtgcc gaagatgaag cgaccacagc
    12901 ttataacgag caattagggt ttgatggtta tggcaagttt gaaaatcttc cttatgggga
    12961 ttatttactt gaagaagtag aagccccaga aggttttcaa aagattacgc cattagaaat
    13021 ccgttctact tttaaagaaa ataaagagga ttataccaag agtgattata tctttactat
    13081 taccgaaaaa gggcaaaagc aaccgattaa aacggtaacg gtcccttatg ggaatctaac
    13141 caatgagaat ttctcagtca gtttgaaccg tttgatgctt tatgatttgc ctgaggaaga
    13201 agatagctta acttctcttg cgacttggaa agaaggagat aaagaattga ctactcttga
    13261 ttctaccgag ctagtcgata aattgagcta taatctacat gaaatcaaag aagactggta
    13321 tatcgtagct caagccatcg atgtagatgc tacaaaagct gcccaagaaa aagataaaaa
    13381 agccaaaccg gtggcgattg cggaaacaac cgcaacttta gcgaataaag agaaaacagg
    13441 aacttgggag attctgcata aattaactgt cgaacaagtt ttagacaaga ccattgtctt
    13501 attcaactat gtgtatgaaa gcaaagaagc ctatgaagct ggtgatgagc cggtagcgaa
    13561 ggatgctagc ttgaacaatc aagcgcaaac tgttaattgt atggtggaac gtcatgtttc
    13621 catccaaacc aaagcgcact tagaagaagg ttctcagacc tttactcatg gtgacgtggt
    13681 agatatgttt gatgatgtat ccattaccca tgatgtacta gatggctcaa aagaagcttt
    13741 tgaaacaatt ctgtacgctt tatttccaga tggtacaagt aaagaaattt ggaaatctgg
    13801 caagattgat tacgaagtga atgacaaaga atttaccaaa accgtacttg cggaaaaagt
    13861 ggatacaagt aaatatccag aaggtacaag ttttaccttc aaagaaatta actatgacaa
    13921 agatgggaat atcaatggaa aacacaatga agatttgaaa gaaaaatctc aaactttaac
    13981 gcccaaaaaa gttccgacaa caccaagtac accagaacaa tctgaaatgc caactgttcc
    14041 aagtggctct caagaatcta gtcctacagt gaaggcattc cctcaaaccg gggagaaaac
    14101 ttccaatgtg ctactgttca ttggctttag cttgatcttt gcgacggctg gctattattt
    14161 ttggaatcgt cggaactaag gtgataagat gaaacatgta aatagtagaa aacaatacgc
    14221 gcgaccgcct cctaaaaaag tggtcgcgct atttttgtat tcaaaactaa caatgaaaag
    14281 aggaaaaaat atggaattga aatttgttgt accagatatg gtcgagacgt tcggaaaact
    14341 aacatacggt ggtgaaggtg aagttctatc ggaagggtat ggtcgaaata ctacaattgt
    14401 tggtcgaagt taccatctgt tttcaaataa acaacgggcc gatgatattg aagtggtggt
    14461 agctgcggaa gccggcgaaa aggattttga ccaagatcaa ccactaaaag ctgtaaatcc
    14521 ccacttaatt gccaaaggct atgaaattga gaatcgtggg tttaccgatt acgtgttgta
    14581 tgttgatgat ttagtgaaag cataggagga aaagaagatg agattaacag aaggtattgt
    14641 cgtagattca ggattaacct ttggcaagtt gcgtttttcc gcattacgtc gagaagtacg
    14701 caagcaaaat gaggacggaa cggttagtaa cgaggtaaaa gaacggacct ataatttgaa
    14761 atcctccgcg caaggtcgaa tgatccaagt cagtattcca gcaaatgtac ccttacgcga
    14821 gtttgcttat gatgcagagg tagagctggt caatccaatc gtggatacgg tcgccaatta
    14881 tgtttttcgg gaaggaacca ccgttaattg gtttatcaag gcagatgatt tagtcttgaa
    14941 acgacaactg aatcaaggaa aacctacgaa ccaaaatgaa ggaaagaaat aggtgaagaa
    15001 tatggaaatt aatgttgaac atattttaga ttgtctcgat caatttggca aaggtgagct
    15061 aacggaggaa caactcacta acgcattaac ctatgatgaa aaaatgtttc tgattatgca
    15121 tcaagggtta ctggaagtag gtaacgatgc caaagaagac tttgatgtac tggattggtt
    15181 aggggaagaa gagtctttct ttatggttgt cgaggtaaat gaaagtttat gtcggcaggc
    15241 agaatctgtt ttggaagaaa tcgatgtgga gatgccggat gccatcgaaa gatttttaaa
    15301 acaattagtg gaaacgaaac aacttcccgt agtagtaaat gactagcata actttttgaa
    15361 attgcccaat gaaatcctat tgggcttttt cgactggagg tggaaaccat caaaatgtac
    15421 aaaggacatc gcatacgcgc aggagatcaa cacttgattt atcactttgt tcttggctgg
    15481 ctaatctttt tgttcattgg ttggatgagc gtcttttatt tacaagaact tagacaattt
    15541 gatatttcta aggtatcatt ttccactagt gaaattggct ggtctatgaa ggatgtaatc
    15601 tgcttgctag gaagtctcgc tctttcagga agcatgatgt tactttatat acactttttt
    15661 caggatcatt ggcgaagtct ttggcatcga caaaagttag ctcggatgat tctagaaaac
    15721 cattggtatg aagtaaagca gactcaaggt gaaggttttt tcaaagattt gaatagtagt
    15781 tggaccaaag agagtatcag ttacttcccc aaaatttatt atcgaatgaa agatggctta
    15841 ctttctattc gcgttcaaat ttcactggga aaatatcagg atcagctatt gaagttggaa
    15901 aataagttag aaagcggact gtattgtgag ttagtagaaa aagaactcaa agactcctat
    15961 gtggaataca ccttgttata cgatatgatt gccaatcgaa ttgggataga agaaatagtg
    16021 gcagaaaatg gggcgttgcg attgatgaaa aatcaagtat gggcgtatga ttccttgccg
    16081 catatgttaa ttgctggcgg cacaggtggt gggaagacct atttcttact caccattatt
    16141 caagcactat tgaagtcaga tgcagaattg tttatcctcg atcccaaaaa tgcggacctc
    16201 gccgatttag gtacgataat gcctcacgta tactcccaaa aagaagaaat ttctgaatgt
    16261 gtggaagatt tttacgaacg catgatagct cgtagtaggt caatgaaaga aatgcccaac
    16321 tacaaaacag gagagaatta tgcgtatctc ggacttccgc ccaacttttt aatctttgat
    16381 gaatacgtgg cttatatggg tgcgaatcgt tttcctacaa gcatcgaata gatgtgaaat
    16441 ggaagcctat tgagattatc aatagtgaca actaatgttt tgagagatgg aatgaaagcc
    16501 ttcaagttga gctgaaacat ccccgctaat actcctacat gctctaatca atgaagtaga
    16561 ttggttttgg tatgaagcta ggtgaagtcg tctgaaatct gcctaagtgc ttgagcataa
    16621 ggctgactat agggcgggcg gctgaaaaag ataactatgg taagaatgtc tgaaaatgac
    16681 tgacgaatct gcgaatgtac gggtctaaaa ggctgatctt attgaaagat aggaacatac
    16741 ggacgtatgg tgagataccg acaagtaagg ttccatgata tgaaaatcgg gatagctaac
    16801 gaagaagcta taatttcaca ggctcatagt agatacctaa ggttatacat gatagctaaa
    16861 aacattggaa cgatgtaagc agaaaactat caattaaatg actacttcta gataggtgca
    16921 tataagtaat aacgaaattg ctttgtttct gtgaaagtaa gggcacagta ccgatgaagc
    16981 gtctaacaaa tgtggaggga tagccctaag tctatttaat aacaatgaat gttgaaacag
    17041 atgaagttca aggatctggt aagaacgtgg gaaaatccgt tatggaggtg ccacgcttga
    17101 acacaaaaat acgttactgg gaatattatg atctacaaga aacattcgat cagctattta
    17161 ctcaaagtag aaacgggaaa aagttttatc aattatatga gttaatcatt tctgaaaata
    17221 atattctttt agcataccgt actatcaagg caaacaaggg gtcttcgaca ccaggaacgg
    17281 attccttcac aattgataac tataaggaaa tgaaccaagc agagtttatc catcttattc
    17341 tcagtcattt agaaaattac aaaccaaaat ccataaagcg agtaatgata cctaaaccca
    17401 atggtgagaa acgcccatta ggaattccat gcatgattga tcgaatgatc caacagatgt
    17461 tcaagcagat actggagcca atatgtgaag ctaagtttta tgaacatagc tacggtttca
    17521 gaccattgag aagtgcaaag catgctctag gtcgcattat gtatctcata aacatcagta
    17581 aaatgcacta tgcagtagac attgatatca aaggtttctt tgataatgta aaccaccgtt
    17641 tactgataaa acaattatgg aatataggaa tttgtgacaa acaagtctta gctattcttt
    17701 caaaatctct gaaatcaccc attcaaggag aaggtatccc gagcaaagga acgatccaag
    17761 gaggtatcat ttctccacta ttatctaatg ttgttctaaa cgacttagac cattgggtct
    17821 caaagcagtg gcataccttt gaaacaaagt atccctatac taaaggttac aataaatttc
    17881 gtgctctaag agatacaaat ctaaagcaag gctatattgt caggtacgca gatgacttta
    17941 aaatcatgac taatgattat ccgacagcat taaaatggtt ccacgctgtc aagctttacc
    18001 taaaagacag acttaaatta gatatttcca atgagaagtc taaaatcgtc aatttgcgta
    18061 aatgtaagtc ggaattttta ggattcgcta tttgcgtgaa acaaaaaggg aaaaaatggg
    18121 tttgtaattc acgtatttct aacaaaaaaa aggatcagat taaagaagag attaaacaaa
    18181 gaatcaaaga tattcaaaag agtcctacag cacaaaatgc tctcctgttt aatgctctcg
    18241 tgctcggtgt tcataattat ttcaggtatg ccactcatat taatttagat ttgaatagga
    18301 tgaactacgt tctttcattc actacttaca accgattatc aaattgtagt acaagatgtt
    18361 accccaacaa agcttcccca acttacaaaa agttttactc aacaacgatg aaaacgtata
    18421 aagtagctgg agtctatttg taccctcttt gcgacgtatc tacaaaaaca atttacggat
    18481 ttaatacgga ggatacaccg tttactccgt ttggtcgtca aagattggag cacaaaagcc
    18541 tacagtctct tgtgttccaa gaattaagaa aattgatgga atcgaaaata ccgaatagaa
    18601 cggttgagta tttagatagt agaatatctc gttactcaat gaaatcaggc aagtgtgaga
    18661 ttacaaaaca atttttgcca gcaaaagccg ttcactgtca tcactatttg ccaaaaagtc
    18721 ttggtggaga cgacaaattc gataacttga gaattattca taaggatatc catcttctga
    18781 tccatacaac aaataaaatg ataatcgatc actacgtgca tgaactgaaa ctggtgccag
    18841 agcaaatagc aaaaatcaac ctttatcgaa agatgtgtaa tctgcaaaac attcaataga
    18901 aaataaatag atggaacgcc gtatgaggtg aaagtctcac gtacggtgtg gagcggggga
    18961 aaagatggag attatatcaa attcttacct atcgctatag atgttaacga caaaagaaag
    19021 tgcggtgatt ttgaataagc ttaaacaaat cgtgatgtta ggccgtcaat ctggtttctt
    19081 tctgattcta gcttgtcaaa ggccggatgc gaaatatcta ggagatggga ttcgcgatca
    19141 gtttaacttc cgtgtggctt tgggtcgtat gagtgagctt gggtattcca tgatgtttgg
    19201 agaagtcgat aaaaattttt ttatgaaacg catcaaagga cgaggttatg tagatacagg
    19261 gggcagtgtg attagtgagt tttatacgcc acttgtacca aaagggtatg atttcttaag
    19321 ggaaattagc aacattgttg gattaaccgt tcatacggaa agagaaaata atagtgtgta
    19381 gcctaggaat atcaataatc ctgggctttt ttattgaggt gatttatgac atttttagat
    19441 ttattcgccg ggattggtgg ctttcgctta ggtatggaac aagccggtca ccagtgtatc
    19501 ggtttttgtg aaattgatga atttgctcgg aggagttata aagcaatcca tgatacaagg
    19561 aaggaggtgg aaatgcatga catcacaagt gtatcagacg aatttgttcg atccctcgga
    19621 ccagtggaca tcctttgcgg cggctttccg tgccaagctt tttcaattgc gggaaagcgg
    19681 caaggatttt ccgatactcg aggtacttta ttctttgaaa tcgctcggtt cgccactctt
    19741 ctccaaccta agtttctatt ccttgagaac gtccggggat tgctcaatca cgaaggaggg
    19801 gctacgttcg agacgatcct ccgaacgttg gatggattgg ggtatgatgt ggaatggcaa
    19861 gtgcttaact caaaggccta cgttccccaa agccgtgagc ggatcttcct tatcggacat
    19921 tctcgagatg catgtaccga acaagtattt cctatcattg gatcgtcttc aacatctgat
    19981 caaaacatca gaaacttggt aaatatcaat ccttccaatc gaggaatggg tggccaagtc
    20041 tatggttcag atagcgtagc accaaccttg accggtgatg aaggaattaa aattgcctta
    20101 ccggtaaagg atgggatttc tgtagcgggt atgttgtcgg gaaattttga acaaggcaat
    20161 aggatttatg aggtaaccgg aacagccccc actttgtcaa cgaaacaagg gggaacgaag
    20221 attatgattc ggaaaaatga aacagaatat caagaggtga agccagggga cagtgtgaac
    20281 ctggcttttc ctaattccac aagtcgccga ggtcgtctgg gaaaacaaag tgtgcatacc
    20341 ttactaacag gagaccaaca agcggtagtc acggatcagt accagattcg aaagttaaca
    20401 cctagggagt gctggcggct tcagggcttt ccagattggg cttttgatcg agcttctcaa
    20461 gtcaattcag atagtcagtt gtataaacag gccggaaact cagtaacagt tccggtcatt
    20521 tttgatattg ctagaagatt aaagggggta aaagcatatg atttatgacg agttgattgg
    20581 agaaatctac tggatgattg gcaagattca ggcagatccg aaattggaag aagaactgta
    20641 ccggctcaat tttgatattc gcaaaaacgg ggtgaaagtc caggtgattc gtatgtagtg
    20701 gatgaggaaa cggatgctcg aatggagctc aatcaagtca tcggtgaatt ggaacgaatt
    20761 gcggaccttg ccaaagaacc tgatatccgc caatacttgt ttgagataaa agcagagttg
    20821 gaaattgagg gtatcaccgc ggagtaatag ggaaataacc cactgatagg cactgaccgc
    20881 gggggatttg cgaagcagaa atcctccgtg gtgctgtgcc tgttcatgga cggcggcagc
    20941 cggccatgat gtctcacccc ccgtatctaa caggggggta caaaaacaca aaaaacaagc
    21001 aagtaaccat aaaaaatgct tgttgtatca aggatattaa gtaatttgta taggtgttaa
    21061 ctcatttgga aaagttaaca ccttgaattt ggaggtgaaa acttggcgca acgaaattta
    21121 gattatcggt tattaaaaga acgacgcaac gaatatggcg tttcacaaaa taaattagct
    21181 actgcttgcg gacttagccg cccataccta aatcagatag aaaacggtgg cgtaatcgcc
    21241 tctacaaaga ccatgagaaa aatttttgat caactggaaa gtttcaatcc cgatttacct
    21301 ttaacgttac tatttgacta tgtaaggatt cgctttccca caacggatgt gcggaaaatt
    21361 attcaagaaa ttctccattt gaaattcgag tatatgcttc atgaagatta cgccttttac
    21421 tcctatcaag aacaatatgt catgggcgat attgtagtga tgttatctca tgaagaagat
    21481 aaaggtgtcc ttttggaatt aaaaggtcgt ggttgccggc agtttgaaac ttttttactc
    21541 gcccaaaagc gtagctggta cgactttttt gaagattgtc taaaagccgg tggcgtgatg
    21601 aaacgcttgg atttagcaat caatgatcga gtggggctac tggatattcc tgatttaacg
    21661 aaaaaatgtc agaaggaaga atgtatctcc ttgtttcgta ccttcaaaag ttaccgttcc
    21721 ggggaactgt tgaaagctga tgaaaaggat ggtatgggca ataccttata tattggcagc
    21781 ctcaaaagcg aggtttattt ttgtttgtac gaaaaagatt atgaacaata tatcaagtta
    21841 gggattccat tggaccagac cgaaacgaaa aatcgttttg agattcggtt gaaaaatgac
    21901 cgtgcttatt atgcgattca agatttgtta aaaggtcgta gcattgaaag taccacgttt
    21961 tccattatca atcggtattt gcgatttgcg gataaagtag atggaaaacg gcgaaccaat
    22021 tggcccttga atgaacaatg gggtcgtttt attggacgga atcggaaaga gattcaatta
    22081 acttctgaac cgaaaccgta taccattgaa cgaacattaa attggctagg tagacaagtc
    22141 gcccctacgt ggaaaatggc taaggagttg gatcgattga atcaaacaac gtatatccag
    22201 gatatggtac agaatgcgcg actctcggac cggcataaaa agattttgga gcaacaaagt
    22261 atggcaatcg aaaacttgat tgtatgaaaa gaggaatttt gatggaaatt gtaaaagata
    22321 tgttattggt acttggtggc agtatgcttg gtgttaccgt gatgtgcttg atgaatgcaa
    22381 gtgcagcagc ggattgagca atggaaaaga aaggaaagtg acaaaatgaa tttcggacaa
    22441 aatttatgtg cgactcgttc cttagtgaaa agctaaggca ctaataaaag aacgaaaaag
    22501 tttggttatt aggagaactg ataatctgac aggtggaatg atgaagtaac gctctgaaac
    22561 gcctgccctg agcctccgac aagcattgta tgaggaaact cagaatgttt gaagctcggt
    22621 aaagacggct gaaagatacc gtaatagttg atgaacatat atcttctatc gaaaactatc
    22681 cagaggtggg tagcgtatcc aacaggtcgg gggtctataa aatatctatg gttagaatgt
    22741 tctataagga actgacgaaa cagcgaatgt acgggtctaa atttgaactt tgtagaaatg
    22801 caaaggtacg agaaatcgta gctggtgtgg caaagtaaga atataggtta tgaaatgcca
    22861 tataacgtta caggcggtat caagccagca ggcttatagc tagtgaccta aggatatata
    22921 tgtatagata agattatcgg aacgaggaaa ggtattgggt tctcatcaag agaataaact
    22981 gacgaagaac aataagcagt tgaactaatg ctgaaaagca gagggcgaac ctaagaaatt
    23041 cttgtaatga gaatggagga atgccctcaa gtcgtgtata tattagaaaa gtattatgtt
    23101 gtttcaataa ggattacgag taagataaaa aagctcactc aatttcaagt aaaggagtga
    23161 agccttatgc ctaaaaataa aaatgaaaca ttgtgtgtag aagatttaag acacgctgaa
    23221 tattacgaaa tgcaaaacac ctttgatgat ttatatgcca aaagtaagaa tggagatatt
    23281 ttcactcatc ttatggatat tatcctatcg agagaaaata tattactggc atatcgaaat
    23341 atcaaagcaa atgcaggcag taaaacagca ggaacagacg gtacaataat taaagatatt
    23401 ggcaaattgc cagcagaaac agttgtcaaa aaagtaagat acattgttgc aggcagtcca
    23461 catgggtatc gacctaagcc agtgaggcga aaagaaatac caaaaccaaa tggtaaaacc
    23521 agacctctag gtattccttg tatgtgggac aggcttatac aacaatgtat aaaacaagta
    23581 ttagaaccaa tctgcgaagc taaatttagt gaaaacagct atggttttag acctaatagg
    23641 tcagttgaaa atgcaataaa agcaacctat aaccgcctac aaatcagcca gctacattat
    23701 gtgattgaat ttgatattaa gggtttcttt gacaacgtga accattccaa gctgataaaa
    23761 cagatatggg ctatgggaat acgggacaag cacttgatat tcattttaaa aaggatatta
    23821 aaagctccaa tcaaaatgac taacggtaca ataacatatc cagagaaagg aactccgcaa
    23881 gggggaataa tatccccact actagcaaac attgttctta atgagttaga ccattgggta
    23941 gaaagccaat ggcaggaaaa tcctgttaca aaaaactatg tggttcatat caataaaagc
    24001 ggtagcccat gtaaaagcaa cgcttacaaa gaaatgaaga aaacaaagtt aaaggaaatg
    24061 tatatggttc gttatgcaga tgattttaga gttttctgcc gctacaagga aagtgctgaa
    24121 aaagccaaaa tagcaatcac tcaatggatt gaacaacgat taaaattgga agtatcacaa
    24181 gaaaaaacaa gaattgtaaa tgttagaaaa agatactccg actttcttgg tttcaagatt
    24241 aaaatgatac cgagaagaaa gaagttagtt gttaaatcac atataagtga taaacaattc
    24301 aaaaaccaaa aagacaagct ggtatcacag gcaaagaaaa ttgcttctcc ctcaaaaggg
    24361 aaaacggaat tagaagaaac aagactttat aattcaatgg tattaggtat gcaaaattat
    24421 tatcagattg caacgaatgt aaatctggat tgtatgaaac tgaatagagc tgtaatggct
    24481 atcttcacta acagattagg tacaaacaaa aggggcagat tgagaaaaac aggcagacaa
    24541 cttacgacaa aggaggcaac aagatatggt aaatctaaaa tgcttcggta tgttgctggc
    24601 gagggcgaac ctattttccc tgttggatat atccaacaca gaaaaccaat ggcaaaggtg
    24661 tatttagcga attgctacac tctagaggga agaaaattta tccacaccaa tctaagtgtt
    24721 gataaattac tgatgtacca gttaatgaaa ttatctttgg aaaatcgcac aatagaatac
    24781 gcagacaatc gaatttcgct attttctgct caacatggaa aatgtgctat aactctggaa
    24841 gaatttcaac aagctaatga aatacattgt catcatattg taccaactgg agctggtgga
    24901 aatgacgatt ataaaaatct tattttggta aaagaggcgg tacaccgtct aatacacgct
    24961 aaaacagaag aaacaataca aaaatatata gctctattga agctaaataa agtccagctc
    25021 ataagactaa ataaatatag agtattagct ggcaatcaag aattaaactt gatataggtc
    25081 tactacataa atacttttca atataaacac gatggaacgc ggagtgcggt gaaagtcgca
    25141 cgctccgtgt gaatgggggg aaaagtttga gatatttata atatcaggaa cttacctatc
    25201 catatatcaa tggtttttaa ccaatgctca atctttagtc ttactagcga ttgtggtcat
    25261 tgg
//
LOCUS       DACCVZ010000038        24258 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.038, whole genome shotgun sequence.
ACCESSION   DACCVZ010000038 DACCVZ010000000
VERSION     DACCVZ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.038"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(45..1340)
                     /gene="purB"
                     /locus_tag="IVW63_001552"
     CDS             complement(45..1340)
                     /gene="purB"
                     /locus_tag="IVW63_001552"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAP7859831.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1353..2486)
                     /gene="purK"
                     /locus_tag="IVW63_001553"
     CDS             complement(1353..2486)
                     /gene="purK"
                     /locus_tag="IVW63_001553"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAP7859832.1"
                     /translation="MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVS
                     DCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTD
                     LLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKG
                     QYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHN
                     NILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRP
                     HNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENK
                     PDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2470..2958)
                     /gene="purE"
                     /locus_tag="IVW63_001554"
     CDS             complement(2470..2958)
                     /gene="purE"
                     /locus_tag="IVW63_001554"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAP7859833.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3374..4681)
                     /locus_tag="IVW63_001555"
     CDS             complement(3374..4681)
                     /locus_tag="IVW63_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAP7859834.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4684..5265)
                     /locus_tag="IVW63_001556"
     CDS             complement(4684..5265)
                     /locus_tag="IVW63_001556"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAP7859835.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5381..5478)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5837..7129)
                     /locus_tag="IVW63_001557"
     CDS             complement(5837..7129)
                     /locus_tag="IVW63_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP7859836.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7126..7749)
                     /locus_tag="IVW63_001558"
     CDS             complement(7126..7749)
                     /locus_tag="IVW63_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859837.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7752..8588)
                     /locus_tag="IVW63_001559"
     CDS             complement(7752..8588)
                     /locus_tag="IVW63_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7859838.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8605..9492)
                     /locus_tag="IVW63_001560"
     CDS             complement(8605..9492)
                     /locus_tag="IVW63_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7859839.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9508..10791)
                     /locus_tag="IVW63_001561"
     CDS             complement(9508..10791)
                     /locus_tag="IVW63_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7859840.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11474..12157)
                     /locus_tag="IVW63_001562"
     CDS             complement(11474..12157)
                     /locus_tag="IVW63_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAP7859841.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12175..12792)
                     /locus_tag="IVW63_001563"
     CDS             complement(12175..12792)
                     /locus_tag="IVW63_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HAP7859842.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12802..13626)
                     /locus_tag="IVW63_001564"
     CDS             complement(12802..13626)
                     /locus_tag="IVW63_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAP7859843.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13619..14179)
                     /locus_tag="IVW63_001565"
     CDS             complement(13619..14179)
                     /locus_tag="IVW63_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859844.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14353..15309
                     /locus_tag="IVW63_001566"
     CDS             14353..15309
                     /locus_tag="IVW63_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP7859845.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15614..16570)
                     /locus_tag="IVW63_001567"
     CDS             complement(15614..16570)
                     /locus_tag="IVW63_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HAP7859846.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16674..17276
                     /locus_tag="IVW63_001568"
     CDS             16674..17276
                     /locus_tag="IVW63_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP7859847.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17364..18863)
                     /locus_tag="IVW63_001569"
     CDS             complement(17364..18863)
                     /locus_tag="IVW63_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAP7859848.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18879..19403)
                     /locus_tag="IVW63_001570"
     CDS             complement(18879..19403)
                     /locus_tag="IVW63_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859849.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19701..20450
                     /locus_tag="IVW63_001571"
     CDS             19701..20450
                     /locus_tag="IVW63_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAP7859850.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20441..21226
                     /locus_tag="IVW63_001572"
     CDS             20441..21226
                     /locus_tag="IVW63_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP7859851.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21195..21911
                     /locus_tag="IVW63_001573"
     CDS             21195..21911
                     /locus_tag="IVW63_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP7859852.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22013..23032)
                     /locus_tag="IVW63_001574"
     CDS             complement(22013..23032)
                     /locus_tag="IVW63_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HAP7859853.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(23051..24109)
                     /locus_tag="IVW63_001575"
     CDS             complement(23051..24109)
                     /locus_tag="IVW63_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014372913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAP7859854.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT         7188 a         5222 c         4225 g         7623 t
ORIGIN      
        1 tttttgctat tctattttaa ttgaattttg caactcactc ttctttattc caaacctact
       61 cgtttgaata tcacgtcaac gtttttcaaa tgatgatgat aatcaaaggc atcgtctatt
      121 tcttctttag ataataccga tgtgatggtt ggatcttctt ctaacagcgg gcggaactgc
      181 acttggttgt cccaagcgta cgcagttttt ggctgaacaa gatcataagc ttcttctctt
      241 gtcattccct tatcgatcaa tttcagcata acgcgctggc tataaatcaa accaaatgtt
      301 gcagacatat tccgcttcat gttttcagga aagaccgtta gatttttaac gatattgcca
      361 aaacgattta acatgtaatt caataaaatc gtggtatcag gcaagatgat tcgttctgct
      421 gaagaatgag aaatatctct ttcatgccat aatgtgacat tttcataggc agtgaccatg
      481 tgtccgcgca ccactctggc tagaccagcc atattttctg aaccgatcgg attccttttg
      541 tgcggcatag cagaagaacc tttttgacct ttcgcaaaaa attcttctac ttcacgtgtt
      601 tcggattttt gcaatccgcg tatctctgtt gcaaaacgtt caatacttgt agcaataagc
      661 gccatcgctg agaaatattc agcatgtaga tcccgaggga gaacttgagt agagatttct
      721 tgtggacgga tccccaattg tttacataca tactcttcaa taaatggcgg gatatttgcg
      781 aacgttccca ctgctcctga gatttttcct gcttctactc cttttgccgc atgttcaaat
      841 cgttcgatgt tccgtttcat ttctgaatac catgtggcaa gtttcaatcc aaaagtagtt
      901 ggttcagcat ggacaccgtg tgtccgaccc atcatcactg tatatttgtg ttcttttgct
      961 ttttcgccaa tgatttccgt aaaacgtttc aagtcttccc gtaaaatatc atttgcttgc
     1021 ttgatgagat agccataagc agtatctacg acatccgtac ttgttagacc ataatggacc
     1081 cattttcttt cttctcccaa tgtttcagaa accgctcgtg taaacgcaac gacatcatgg
     1141 cgtgttaatt tttcgatttc caagatccga tcgatatcaa atgatgcatg ctcacgaatt
     1201 tttttcacat cttcttgcgg gatttcacca agttctgccc aagcttcatc tgctaaaatc
     1261 tcgacttcga gccacgcacg gtatttgttc tcttccgtcc agatattccc catttcaggg
     1321 cgtgtataac gttctaacat gttttttctc ctctaatccc aaatattcgt ttgtttgatt
     1381 tcttccagcg tttgctggat gtcttctgtc aagatagtga tatgtcccat cttgcgacct
     1441 ttttttgctt gtttttttcc atagaaatgg aattgccagt ctggcttatt ctcaatcaag
     1501 cgatagcttt ccagcagttg ttctcccaaa acattgacca ttactgcatt gcttatcaaa
     1561 cgtacttttt ctcctaatgg ccaaccacaa atacctcgaa tatgggcatc gaactgactc
     1621 atagaacaag cttcaataga ataatgtcca gaattgtgag gacgaggagc taattcattc
     1681 acatatagcc cgcctgtttt tgttaaaaac atttctaccc ctaaaacacc tgaaaggctc
     1741 actgcttctg caatcacacg ggcaatacgc tcagcctcct cgatcacatc ctgatcaatc
     1801 gcggctggag caatcgtttc atgaagaata ttgttgtggt ggatgttttc cacgaccgga
     1861 aaagtcgtga aatctccttg accatttcct gccaccatga tcgaaatctc tttttcaaac
     1921 gggatccatg cttctaaaac acaggttcct tctcttaaaa ggtccatggc aggagctaga
     1981 tccgcccgac ttttcaaaac atactgcccc ttgccatcat agccgcctcg agtggttttc
     2041 aaaacacaag gatagccgat cccgtcaatc gcatcttgga tatccgtcgg actgacgatc
     2101 gttgcataag gagcaatcac gatgttattc gtttccaaaa aagatttttc taacaggcgg
     2161 tcttgcgtaa tcgcaagcaa gtctgtccct tgaggaataa atgacatggg taaaatcgca
     2221 tttaacgcct ctacactgac gttttcgaat tcataggtaa tgacatctgt tcttctggca
     2281 agctctttca gcgcaaaggt gtcatcatag acactttcaa tgtgccaatc tgcaacttgt
     2341 gcggctggac aatcgctcac aggatccagc acacctactt taaagcccat ttcttttgca
     2401 ctaatcgcca tcatacgacc taattgaccg ccaccgacga tcccgatcgt tgaaccaggc
     2461 aacaaaggtt taaccaagtt gatcactact ttctataaca gttttagcca acattgaacg
     2521 tctttcagcc aatttagcct ccaattctaa atcatacatg gaaagcatct gtatcgcaag
     2581 tagtccagca ttaattgctc ccgcttttcc gattgctgta gtagctacag gtactcctcc
     2641 aggcatttgg acaatcgaaa gaagcgaatc caaaccattt aatgttcgtg attggaccgg
     2701 tacaccgata accggcaaag ttgtttttga tgcgaccata cccggcagat gcgcggctcc
     2761 ccctgctcct gcaataatga ttttgattcc tttttttcga gcgttttgtg catattcaaa
     2821 catcaaatct ggggttcgat gagcagaaac gacctttttt tcataagaca caccgaattc
     2881 atccaatatt tgacatgctt ctttcattgt ttcccaatct gaagtactcc ccataatcac
     2941 agagattttt gctgtcattg tttttcctcc cagtttttct acattcatat tttaacaatc
     3001 actttttttg atgtcaaaga aatttcgaat gttaacaaag aaaaacattt tattgttcgt
     3061 gtttattaaa gataaaaaaa aggaatgtga caaaagttag gtcacattcc tttttatgga
     3121 taaacggtgt tctcctgcca actcctcggt cacaaggaac aatattcaac aaacatgaga
     3181 agcttttttt tgaaattgtt ccttgtgact cggagatgaa cggcaggctc acgacctctt
     3241 ccttcaacgg tgttcaatca gctgaccctc ggtattagct caaacaaacg gcaaaatacg
     3301 aggaactatt tttccgtttg tttctctaac aatcaggtca aaacgctgat ttcacaacct
     3361 ttcttttgct ctattacttc ttgaaggctt cttccaatat ttcttcatct tttttcaatc
     3421 cattaaagat caaattcaat atgatagccg taatgctact cattacgatg ccatttccag
     3481 tgaacatttg caatgtttgc ggcatttgac tgaataatgt cggcgtaaca ttgaaaccca
     3541 gcccaaatcc aacagaaaca gcaacaatca atagattttt atcattgctg aaatcaactt
     3601 ccaacagcat acggattcct tggactgcca ccatcccgaa catgactaac attcctccac
     3661 caagtaccgg ctcagggatg atttgtgcta acgcaccgat tttagggaat aatcctaaaa
     3721 caatcaagaa gaatgcagag aaatagatgg gttttcttgt tttgattccc gaaagttgaa
     3781 ccaatccgac attttgagaa aagccagtat aagggaatgt attgaaaata ccgcctaaga
     3841 taacggcaag tccttctgca cgatatccct ttttcaattc ttcttctcca acatttttcc
     3901 cagtaatgtc accaagtgca aaatatacac ctgttgattc taccatgctg accatggaaa
     3961 tgatgatcat tagtaaaatc gaccatacgt cgaaagttgg tttaccaaaa taaaagggtt
     4021 gtggaacatg gaacaacggc gcatctccaa tcgcgctcag atcaatcatt cccatgaaag
     4081 cagctaagat gcttcctccg actaaaccaa tcaataccgc gattgaacga atgaaccctt
     4141 ttgccagcat ttgcacgcct acaattagga gaatcgtcac aaatgcaagt agcagatttg
     4201 ttttgtcacc aaaatcagct gctgttgcat tacctccacc cattttctcg attgctacag
     4261 gaatcaaagt caaaccaata acggtgataa ccgttcctgt tactatagga gggaatagtt
     4321 ttttaatttt agaaaagaca ccagaaacta acacaacaaa gatcccagaa gcgataatag
     4381 atccgtagat agctcctact ccttcattgg ttccgatcaa gatcagtgga gctactgctt
     4441 ggatcgcaca tcctaaaacg acaggcaagc caattccgaa aaatcggtta actgtcaatt
     4501 gcaataatgt cgctaatcca cacataaaga tatcaattga aatcaaataa gtcatctgtt
     4561 cttgattaaa gcctagtcct gtaccgatca aaagaggcac cgctactgct cctgcataca
     4621 tcgctagcag atgctgcagc cctaaaaccg cagcttttcc attttgtgtt tctttttcca
     4681 cgattatgcg tcctcctcaa gaaactcaac ttgtccattc gtcaaggaag caatacgcgc
     4741 aagagaaacg actctcaatc ccatttcttc aagtaactga cgtccatctt ggaaagactt
     4801 ttcgatgacg atcccgattc cttctacttg cgctccagct tgctggcata attcgatcaa
     4861 tccttttgcc gcttgtccgt ttgccaagaa atcgtcgata atcaatactt tgtcttctga
     4921 agataaaaat ttacgagaaa tagaaatcgt acttgtcact tgtttcgtaa aagaataaac
     4981 agaagctgtc aataattctt catccatcgt caaacttttt gcttttctag cgaagatcat
     5041 tggaacatct aattctcttg cagcaaataa agctggtgcg atcccagaag cttcaatggt
     5101 cacaactttc gtgattcctt gttctttaaa tacttctgca aaccgttttc ccatttgttc
     5161 catcaataca gggtctactt ggtgagtgac gaagctgtcg acttttaata cgccctcgcc
     5221 taatatacgt ccgtcttttt gaatacgttc aactaattct ttcactttat ttgctccttt
     5281 atcatttatt aataccgaaa taaccgcttt tgtgcaaaaa cctactatgt ttctgttaaa
     5341 gaaaaacacc ctccacttta tcataagaaa agaagggtga aatagccaat cttttactta
     5401 tagtccagca tttacggtac tggctagaaa ctgtcatcca tattatgacg atatataagt
     5461 aggtatgtaa aactaataat agtgtaaatt cattttcttg caactgtttt gcacgtgaag
     5521 gcagtttgcc atatttgaat aaaaaatgtt gtttcaaata ttgaaaacag tctaacacta
     5581 ctttctgaaa ctgacaacgt ggtttactta tttttttgta aaatctaatg atttttaatg
     5641 cattattcct ttttgttcgg gtttaaatag ttatttttat tttctcctat ctaaaaaagc
     5701 agcccacata aaaagaaggc atgacaaaaa gcatgtcata gccccttttt ccgaataaat
     5761 agtgttcaaa agacagccta tcggcaataa ggcaagattt tataaactac gggaagtaat
     5821 ttccgtaaat ctattcttat tcttttaagc tgacaagctc gtcaatcact actgcttttc
     5881 ctgaagcaat agaatgattt gctgcgattc ctgtcaaaat cgacaaaata ccatctacgt
     5941 gagttgctgc ccgattccac ggatcttctt ctttttcttc accaaataga tcatctaata
     6001 aacgcggatc tcctccgcca tgtccgcccg cttcttgttc gacgattacc tcatatggct
     6061 caccgaacat cggatagaca tggatggact gaagaacggc tgctccttca tcctttttat
     6121 ctccacctgc attgatgtaa gacttttcga tcactttcat ttcgatccgt cctttgctgc
     6181 cattgaaaga aacattgaat ccttcccacg gcatatacgc gtttagcgaa tacgtcaaaa
     6241 tcgcaccagt ttcatatttg accgttacgc ctagtgtatc ttcaatagag atatcatcgg
     6301 aaaatacact gcggtcacga atatatccac tgtctttttc tgcttctaaa tacatttctc
     6361 gcaattcctc attggctgac aggtctatag caaatggatc agctttagct agttcgcttc
     6421 catagcatcg actgtaaaat atttctactc cgcgtttctc cgcattatgc atcccataaa
     6481 agtttaatcc accgaatgca aatacctttt ggggacggct gttcaaccaa aaattcacta
     6541 gatcaaaatg atgggtagat ttatgaacaa gaagcccgcc gctattgtgc ttatttcgat
     6601 gccatcttct gaaataatct gccccgtgtt gcgtatttaa cagccattcg aagtggatag
     6661 aaaacacatc accaatcaca tcactttcta tcagttcctt tatcttcgtg tgatacggtg
     6721 cataacgata attaaaagtg actcgcaggc ttcttcccgt ctgtttttgg accgttatta
     6781 tttcttgagc tttttcctca tcgatagtca gaggtttttc gcaaataaca tcatatcctt
     6841 ttttcattgc acgaatgata taatcatgat gcgttcgatc tactgacgta ataatgactt
     6901 cagccggccg tacgtcatcc agtagttgct caaattgtga tggcatacat gtctttactt
     6961 ttttctgtcc atacttgttc acaagtatcc gatttgcata atccatcctt gtttgagata
     7021 catcacaaaa accgactagt tcacaagttt gatgatacgt agaggcaatt gcctcataaa
     7081 aaaaacgcgc tctcccacca agtccgactt gtacatattt tttcttcatt taaagtcatt
     7141 ctccttttct tttaagcaaa atactgtgac aaatggcagc cctggataca gtaatgcagt
     7201 gagtaaaaaa tcatgctgta tacaccagaa cagtccatac aaaaggcata aataccacag
     7261 aaaccccttg acgttttttg acaacagcca gatattcctt ttgatcaaat aaacaagact
     7321 atctgcttta tcttctttgc agatatcaat tagcgtacta aaaaaactat gggatacaaa
     7381 aagcaacaga cacaatagaa aaggaatcag ataccaagct ccaatctttc ccactaataa
     7441 ataccaatca actgcaaaaa taatgacaaa cagctgaaac aacgtaatga tgaaacacat
     7501 ccgtttgatt tttcctttcc tccaacatac ctttttttct gccaagtaat ggacagatag
     7561 ataataagaa ggatacatca tcaaaaaata aatcagatag acaacacgag cagacagcac
     7621 taatcctaaa gtgaacaaac atcctagaac taaagcgaaa agagcattac tgataagact
     7681 ggttaaaaaa atccgacaga catagtagtt gagcttgtaa agaaacatct cttctattgg
     7741 ctttttcata ttcagccctt cagaccgctt gtactgatcc cctggacaag atatttattg
     7801 aagaataaga aaatcagaaa aaccggtagc agcgacaacg tagacatcgc aaacatactc
     7861 gcgtaagtcg tactagatcc agcgtctgca aataatttga tggcaatcga taccgtgtaa
     7921 gatctcggct tgtttaaata aatcaatggt cccatgaagt cgtcccattt ccaataaaac
     7981 tggatgatga tcgtcgtgat gatcgaaggt ttcagcaaag gaaaaataat tttggtaaag
     8041 acactatact tgctgcatcc gtcaataatc gctgattcat ctaactcttt ggggatgctg
     8101 accatgaatt gcatgatctg gtaaatgaaa aatgcttgtc caaaaaaatg tggtaaaatc
     8161 agcggcacat acgtcccaac caaattcagc cgattgtaaa taataaactg cggaatcaaa
     8221 atcacttgtg caggaatcat catcgttact aacatgacga cgaaccagaa tctttttcct
     8281 ttgaaatcga ttctcgataa tgcgtaagca atacaagtcg agctcagaac tgtccctatc
     8341 gtcgaaactg cagagatgac aaacgaattc ctaaagaaag taaaaaatga aattccagca
     8401 aaccccgccc atccttttgc gtaattttcc cattgaaaag tctctggaat caaattcagc
     8461 gaaccactca taatctcttg atccgtttta aaagaacctg cgatcatcca taagaccgga
     8521 taaatcatga ctagacctaa tagcaaaata aaaccgtatt gaaaccattt cgttactgta
     8581 ttattcattt cttcctcctc tcattcacac aacgacccat ttttttgatg atttgaaaat
     8641 cagaaaggtg acagctccca taatcaacag catgatccac gaaatagcac tagcataccc
     8701 catagaatta aaagaaaaag cttggttata cacataaaga gcataaaagt tcgtggcatc
     8761 attcggacca ccttgggtaa tgataaatgc ctgcgtaaaa gtcataaacg ccgcgattgt
     8821 ctgcataacc aagttataca aaatgatcgg cgaaagaaga ggtaacgtga tcttgtaaaa
     8881 cgtctgccat ttgttcgctc catcgatctc tgccgcttca taatacgagc ctgggatctc
     8941 tttgatacct gcagcaaaga tgatcattgc cgaaccgaat tgccaagcag acatcaaaac
     9001 aagagggatc atgaccagtt tttgatcgct aaaccaggaa agcgcaggtg cgcctaatcg
     9061 ttccaggaaa atattcacta acccgttttt agaaaacaac tcccgccaaa ctagagcgat
     9121 agaaatactg ccaccgatca aactaggcac ataatacaaa gaacgaaaga aagtcgttcc
     9181 tttgatattc ctcgttaaaa gataagcaat caatagacca aagatcagtt tcacaggtac
     9241 agatgcaaat acatagagaa aagtgactcg gatggagttc aaaaaacggg catcactcag
     9301 catctttata taattatcca agccgatcca tgagactgga tttcccaaac gataatcggt
     9361 gaacgaataa taaagtgaca agatcatcgg tatcactgtt atcaatagaa atcctaggat
     9421 gaatggagaa gcaaatacgt aaccgaccac attgtcttga tccaagaacc gttttagttt
     9481 ttcttttttc atgccttcct cctgctgcta tcctagaatg tttgacgcaa actcataaag
     9541 actctctgct gcttcttctg ctgttacttc ttcataaatg actttttcaa ctaaaagatt
     9601 gtattggtct tgaatttccg gattcaaagc actatcaaag acattcactt cgccgttgtc
     9661 catatcggaa atcatttcta aataatcaaa tgtcgcttgc aaagttgcat catctgcacg
     9721 agcgagctgt tctcgaatat tcgacatgat tggtacacca cgttctcctt ttaaaatttc
     9781 attggcttct tcactgtttt gaaagaaatc aataaactta gcagcttctt ctttatgggc
     9841 tgagcttttt gccatactca gcatttgcga agaacgtaaa gggataccag attctccatc
     9901 tgcttttctg cgaggtggat taatcaactg aatctccata tcttcaggag cccctgacaa
     9961 tatttctgtc aactggttac ttgatagaaa caccattgcc gcttctctat ccctaaccgc
    10021 ctgaaaagac agatccgtcg tacttgcagc tccaccacct ggttctggat gggccccttt
    10081 gtctaccaga tttttacgca gctggaaaaa atctgttaga tagtctggat tttcaaatcc
    10141 caagctgtta gatagatctt cccgattata aaaattcaat cctttctcaa cttgtggtat
    10201 ttgaataata cagccagcta taaaatcttc gaatcttgaa atagcataga ttcctaattc
    10261 ttcagtgatt tgatagctga tttgttcaaa ttcatcccat gtccaatttg aagctggttc
    10321 agggatattt aattgttcaa atatattttt attgtaagca atcgcaaacg aattcacccc
    10381 gttagacagt ccaactaatt gcccgtcgta agtcgtcgtt gctaaatagg attcatctgc
    10441 attagaaata tcaattatcc cttgctccac atattcatct aatggttcaa tctgattgat
    10501 gtattgagga aattgattgt tcagttggaa aatgtcccag atatcatctg atgctgctag
    10561 tgtacctaat tttgtgtaat atccttcata atcataaaat tcataatcga tcgtcacatg
    10621 gggatttttt tcttcataaa gctcgattac ttttactgtt gcatcgtgtc ggacttgcga
    10681 accccaccaa gccatgttca gcgtgatttt tttgtcatct tcttgcccac aagccgtcaa
    10741 gaagaataac ataacactta aagctaagat gattctcatt cttttcttca ttctctgcac
    10801 ctctacttcc attgttattt ttcaatatac tgtattttta tacagaacat atttattaaa
    10861 cgatcttttt caaggggaat aaaaaccaag acttgcctta tcgttctgcc taggatgaac
    10921 aactcaatac tttcaagaaa aattagatag tgctgattct tctttcatcg ctaaaaacac
    10981 ttcttgcttc aatgatggga ggataattac gcaaagaaaa aaggatatca gacaactgcc
    11041 caatatcctt gacatagcta aataagcatg cttcttcgtg tgcgctcttc cctaaaaaac
    11101 agaaaaataa ctagtaattc tgtatgaaat taggtacaat atacacgtcg atgcacaagc
    11161 attgactatg gcaacttgat tggtcagttc ccgctgactt ttcaagcccc gacaatttag
    11221 ctgctactaa attgtcgggt gcctttttta gtttttattc gtttttcatt ctatagaaag
    11281 cgcttcaata aatcaagaca tttttttgtt agaatgctaa taataacaaa aggttttaac
    11341 tcttcttatg tacattacag gtaaaaaaac aaaaaaattt ctcttttttt tgaattctga
    11401 acaaatagta ctggagtaca aaagacgagg aagagccact atctgctctt cctcgtcttt
    11461 tgattctcac ctgttattca tgattctttt tctcagtttc ccgatatttt tccattttac
    11521 gactaaaaag ctctccgcta cttggtggcg tatatgtgat ggcatttgct cctgcttgaa
    11581 tggtctcagc aatactttct tccgttggac cacctgtcgc aatgatagga agttcaggat
    11641 attttttacg aaaatggcgt actgcttctg cagtttcttt acctgcactg atattgataa
    11701 tcgaaatacc agctgctaac ttttcatcta tttctgtata tttcgacgtt accgtactga
    11761 taactggaat atcaactact cgacaaactt cttttactgt ctctaaaggc gtaggaccgt
    11821 tcaaaacgac ccctaacgaa ccttgcgctt ctgcgaacat gctcatgtag gaagaacgag
    11881 caccttgtgt caaaccacca cctacaccgg agaaaactgg aatgtcagct gcctcaataa
    11941 tgcttttagt aatcgctgga tgaggtgtaa aaggatacac agcaattact gcattcgcat
    12001 ttgtattacg tatgatcgca atatccgtag taaagatgat cgaacggatc aattttccaa
    12061 atatcttgat cccgcttgct tctaaaatga tttccggtac tcttacgata tcttttctca
    12121 attccgtcat gatttctggc gtaaattgtt ctgccatcag ccacttctcc tttgctatct
    12181 ccggtcatac tgattcaatt gatacgtctc gatgacctgg atgatttttt gcgcataacc
    12241 ggggtctgtc gcataacctg catcttgcaa tgcttgtgcg gcttcctgat agttggtggc
    12301 cgtaatcact ttttcataca gcgcaggatt ccaatctact ccttggacga acagttgtgt
    12361 atggtcatcc atggactgtt cccatgaatc atacactttg aagtctcctt ggatagttat
    12421 ccattcttcg ttaacaaatt cctttgtttc caggcttact ttcttctgat ccccataagc
    12481 cttgatcccg aaaagattat tgtatttgct agccaaggta ctttttcccc aatttgattc
    12541 taatatagct tgtcctaaaa tgatactagg aagcactcca taaccatctt gtagttcttg
    12601 ggcatgcgga acaagccgtt caataaattg ctgatgggat tgcgcttcat tttcttgctg
    12661 attatcagta aaaggagaag acagattctt caaggaaaaa acaaaggcta agagtatcac
    12721 tgctacaccg gcaaccactg ctggccaacg gatattcttg cgcttttgct ttttccactt
    12781 ttttttcgcc atgatcaatt cctacttttc atttaattca ttcagatatt cttctagcgt
    12841 caattggtgt ttggtgatat actcagcgtt ttctttaccg acataacgta agtgccaagg
    12901 ttcatatgtg atcttagtta tatcttcgtg tccttttgga taacgaacga taaatccata
    12961 ctgcgcagca ttatctgcga tccatttagc tccaggctga tctccgtaac ttgcatccaa
    13021 tacagtagaa ggataactgt tgtaccagtt ttgatcgacg acatcgactg ccagacctgt
    13081 gtggtgttcg ctgtatcctg gctccgtaat cgtttcttta gtaatctttg tcgcctcctc
    13141 ttctgataca ccttgacgac tcatcacatc ttggacattt tgttcgaaaa cttgttgttg
    13201 ggatgataca gaccggtaag ctgagaccat cactaatgga aatccagctg cttcagcagc
    13261 cttggcaaat gcttcatatt ctggagcaat gcgtttgtcg atcaagtatc cgttacttaa
    13321 tgatgccaat tgagtagact catcaatttc tttttctaat ttgtgatctg gaccaaccaa
    13381 aactagcttc caatcgtctg ttttaacatc tggcaattgt ttggacgtac gatcttttgt
    13441 ttctttgtcc tttaccttgc tgctggttgt ttgactgttc ttttctttac tagcagttgt
    13501 tttggtgctt gttcgttcga ctgcttgatt gccggcttga acatgcgaat catcatcgct
    13561 aaaaataaca tagcccattg ctgcgatcat aatcacaact gctccaaatc ctaaaaattt
    13621 attcacttga aaaatccttt cgttgttctt cacgttcccc attcgcctca tgaacgtaag
    13681 tttcttccag attttcattc acccaatcga gaagttcgat tttttctcct tcgatctgtt
    13741 tttgaacatc tgctggcaga cgaaaattca aaatatcatc atagccccat tcatcatatt
    13801 gaatacttac tttcaagtca aggtatctac cagcctgctg attatttttc aaagggatca
    13861 gctcgacttt tgctgctttg ctgctaagcc atttttgcgc gatgcgtgtt ttgatttgct
    13921 tgtactctgc aacggcaacg tttcgttttt cgggaaaaat aatcgtttga cgcaaaatct
    13981 tttgcgttag catccattca taatcagtga aaagattttt tactttctgc atcgcttcag
    14041 atggcagatt tttctcgcca tctttccatt tttgccattg ttctggactg atcagcaagt
    14101 attcatctaa aaaatttttt tcagtttcaa actgttctaa taatacactc ataataagat
    14161 caatatatac ttgatgcacg tttatcccct ccttttaact attctactta agttttgatc
    14221 aaaaagcacc tcttaaatcg ctgctttcat tttttttaat gtttcaagtc ctctcctctt
    14281 tattcttcgt gatttttgtt ataataatag acagacaaga aactcaatcc aactatgaag
    14341 gagcgttttc agatgaaaaa atatcaatgg ggaatcgttg gtcttggtac catcgcacat
    14401 gagtttgccg aaagcttcaa tcaagagacg agcgaactaa cagcagttgc ttccagaact
    14461 tcagaaaaag cggaaaactt cgctcaccgt tacaatattc caaaagctta cggaagctat
    14521 caagaaatgt tagacgatgc tgaaatcgac atcgtgtaca ttgctgtacc aaatagacag
    14581 catatcgacc atatcttggc agcattggaa gcaggcaaac acgttctatg tgaaaaagcc
    14641 atcacgatga ataaaaaaga actggctgac gctatgcgct tagcagaaga aaagaatttg
    14701 atcttagcag aagcgatgac aatcttcaac atgccacttt atcagcagtt acgctcaata
    14761 atggatacag gaaaactggg ggctttaaaa atgatccaag cacctttcgg cagttacaaa
    14821 gaaccagacc ctaaaaaccg gttcttcaat ccagaattag ctggaggagc tctgttggat
    14881 atcggtacgt atgctgtatc tttcgctcgt ttctttttga gctctcaacc tgaagtagtt
    14941 gcctctacaa tggttccttt tgaaacaggc gtggacgaac aatccgtcac tatcttgcgt
    15001 aacaaagaaa atgaacttgc tgctgtcagc ttgacttttc aggcaaaaat gccaaaagtc
    15061 ggtatcgttg cctttgagaa cggttatgtg acgattgctg attacccgcg tgctgatcgt
    15121 gcggagatct tatttacaga tggtacaaag gaattcatcg aaagcgggaa tacatctgaa
    15181 gcaatgaatt acgaaataaa gaatatggta cacatgattg aaggtgactt gcccaatcgc
    15241 tctctcttct tgacaaaaga tgtcatcgaa atcttggatc aaatgcaagt tctatggaaa
    15301 aatatgtaat tttaaaaggt tgtgaaaaag ctgttctgca tcaagtaata agaacagcca
    15361 aacaaaaata gctcctccta tttttcgttt ggctggactt attaccgcag aggaaagctt
    15421 ttgaacaccg tttaagaaag aggttgtgag cctaccgttc agctccgagt cacaaggagc
    15481 aatttcaaaa aacagcttct catgtttgtt gaatattgtg acttgtgacc gaggagttga
    15541 caggagaaca ccgtttaaag aagaggttgt gaaatcagct ttttgacctg aatattagct
    15601 gaattcacaa cctctatttt tggatttttt gttgggagaa ttctgccttg atttcaataa
    15661 aacttttaaa agactgcaaa aactggaaca attctgctcg atcctcgaat tcagggcgac
    15721 tagtcggcag aggcatttgc cgatacaata cataaacttc ttcaatacgt gttaaaattt
    15781 gtctgccatc atttgactct gaaaatgttt ctgcagtata aatcaataaa ccatagatat
    15841 gttttccata ataagctggt tgctggattc tctctagatt ttccagcatg tctttaatca
    15901 cattggcctg tgctcttctc atagagaagt aagtttcgta gtatagcggc tgtctgagcc
    15961 agtagttttc ttgatgttct ctggcatctt cttggctttc gcgaatgaat gtcagtaaat
    16021 gttcgcattt gatctgcaca tcttctttat tttctgataa aagaaattct gccatttgtc
    16081 tcaaaatatt tcgaaattct ttttcgatct gtatttggtt ttccttcagc tgcttcgtac
    16141 gatctggcat gtaaacattt gcaagcaaag caaatactaa tccaatcgcc attaatcccg
    16201 cttcattgcc gatcagctgc caagacatgt tttcctccac taaataatga gtgaccaaaa
    16261 ccgaatttac tactatccct tcggttaatt tgaagcgaga ggcaagcggg atgaacagga
    16321 ataaaaaaag actgaagcca aaaatagtat acccaacagc aaaaaaactg aacagtgctg
    16381 ttgccgtagc taatataaag gctgcgattc gattcatgcc cgtacgcaat gtagagcgct
    16441 tggtatttcc tacacttaat aatgcaatga tccctgcagc tggccaatac aacagcgata
    16501 agctacccgc tgtgaccatc gaaaagaaga cactgatcac tgttttgact gttcgcattc
    16561 ctatacgcat ttacttcccc cttttttatt ttaattatac ttgaataatg aaaaactagc
    16621 tatcagacaa aagtttaggt atgatagtaa aaagaccaaa aaggagaatc tctatgcaat
    16681 ttggccgttt tcgactaggt atgcgtacga tcaaaagtgc cttagctgtt tttttatgta
    16741 tcttgttttt tcatttgact caacgaggaa tcccgatgat tgctgcatta tctgctgttt
    16801 tttctttgcg tcaggacttg actacaaccg tttcttttgg aaagtctagg atcatcggca
    16861 atacattagg tggtacatta gctatcattt atttttttgt caaaagctat tttcacaatg
    16921 attttttggt agaattgatc ttgcttccta ttctagttat tattgtgatc gtcgtgtcag
    16981 atggtattaa caataattcc ggtatcattt ccgcaatagc tacgttgttg ctgattgcgt
    17041 tgagcatccc tcaaggcgaa tccgctttgt atgctatcca acgtgtacta gatactttta
    17101 tagggacatt cattgcaatc ggtatcaatt tctttcttcg tcctcctgaa acagaaaaga
    17161 aggaagaact atcagaagat ttggtcgaac tccaaaagaa agaacgattg ctaagaacaa
    17221 atttacaaga gatagaagct aagatccaaa aacaaaagaa aaatagcgag gactaatttt
    17281 cttttgcaat aaaataaaaa aatggagaga agaactttaa aaagtcttcc tccatttttg
    17341 attgaacggt gaagtgtact actttattct tccttcatcg agttttgttc tgcctctttt
    17401 ggcgcttcat acatatttac ttggctagta gtcccacgtg tcgacaaatt ctctacgatt
    17461 tccttcaagt caagtcctgt tgtcgctttt agtgtttctt gagtagaaga aagcaaattt
    17521 gtggcataat ttgtcactcg gttcgctcca ctggtttctc ctgaactgct tcctgtatcg
    17581 acaacagaga ttttttcgat atttcctagc ggctgtgctg cttcgcgcat caattgcggt
    17641 agcatatcga taaccatact caagacagct gcttcgccat attccttgaa ggcattggcg
    17701 atcttttgtt ttgcttcggc ttctgctttt ccttttgcta gtgctgcttc ggcttctgct
    17761 tgtccagcta aacgtgtctt attggcttcc gcttctgcca gtgcttccac acggaatcgt
    17821 tctgcttcgg cttcagtcac ttctttgact ttttgagctt gtgcttcttg ttctttagcg
    17881 taccgatcgg catctgcttt tttcttcact tccgaatcat attgcttttc acgacgtgtg
    17941 atttcttttt cttccagttc gatttgtttt tgacgttcta cgattttaat ctgcatttcc
    18001 tgttcgatta cttgttgttg tgctcgggca ctttctaaat tgtaggcttg gtctgctttt
    18061 gctttagcaa catcttgttc ttgtttgtag gttgctaatt tcagttcttt ttcttttaat
    18121 gattctgcga tctctgtttg tcgctgtaat tcagctgctt gtgattcttt ttctgcttga
    18181 gcttttttga tacgcgtttc ttttagagct tccgcttctg ctatatctgc atctcttttg
    18241 acttgggcga ttcttggttt ccctaaagag tcaagataac cgtttttgtc tctgacctct
    18301 ttgatagtga aagaaacgat gatcaacccc atttttgcaa ggtctacaga agcgacttct
    18361 tgtacgcttt gactgaactt atcgcgattt tgatagattt cttctacagt catagaacca
    18421 agaatcgagc gcaagtgtcc ttctaatact tctcttgctt cattttccag ttcttctctt
    18481 gtcttgccta aaaactgttc tgctgctgta gcaatctctt ctacagatga accgattttg
    18541 atgatcgaag taccatcaca catcaccggt acgccttgtt ccgtatacac ttcaggggtg
    18601 gagacgtcca atttactcga taatagactg atccgattcg aacgttgaaa aactggcaag
    18661 acgaatgcgc cacctccacg cacaattttg attttgttat tgctttcatc aatgtgcaca
    18721 tttttgcttc ctaaataact tccactgatg atcaacgctt catccggttt tgctgtctgg
    18781 tacttcgcta caaagacgat cagcaacatc agtaaaatca aagctgcgat tgcgatcgcg
    18841 ataaaaacaa ctggtatttc catttaacac acgctccttt aagcttttat catgctttca
    18901 taaggcatga cataacagat tctttccttg atctcaatga tcaatacttt cgttccccgc
    18961 tcagctgtct gttcttgggg gctgtaaaaa caagctggac gactaatgga accggtaaca
    19021 cttttcaact gaatttctcc catacctcgt acagggatcg gtgtgatcac aacagctact
    19081 tgtccttcca gagttttttc agaagacgac atcgttgatt cggcatgttt catcggcatc
    19141 aatatataga aattaagcaa aaataccaac actatcgata tgcctccact agcaataaat
    19201 aaaaataaag atgattgatc tgttaaacgc tcacctagaa aaccaaataa gcttgtgaaa
    19261 gttaaccaag ggataataag catcggatca agcgggccat caaaatcgaa tacatctcca
    19321 aaaataatca ataggactgc caatcctgca caaatcagca atgtatacca ataaatcgtc
    19381 tcaagtgcga ttccccctat catatacacg cctccttcca tttctacgtc tatcatacca
    19441 atgtttgaaa attctgtata gcttctttta ccgactcagt ggtgtttttt ataggaaggt
    19501 tgtgtttatc gttgacaatt tgttaaattt ttgttttcat gttaaaattt tcacaataaa
    19561 ttctttcgag gtagcctatg tttccttttt ttaagaaaaa accattaaag ctccagaaca
    19621 cgatcatcct tgtcgtttgt ttctccacat tcgtttcttt gattgtttct gccatattga
    19681 tcaggaattt tattctttcg atgaaccgat ctagtgtgtc agataaaatc tctagcattg
    19741 ctaaaatcgt tgccaatgat aaactcatcc aaaaaaagct gcagactggt gacccgacac
    19801 atgcgattca aggaataaca aatgaaatca tgattgcatc gaatttagat tttatcgttg
    19861 tcatggaccc tgaaggcatt cgatattctc acgcagaccc aagttacatc ggtcttcctt
    19921 tctcaagtca tgaagatgtg aaaaaagtga ttggaggaca agaatttttc tctgaaaaag
    19981 aaggaatgtt agggttcggc ttccgctatt tcgtccctat ttattatgat caagagatta
    20041 ttggtgcagt ttgtgttggc ttaacaaaca acacgattga caatcaagtc aaagatggac
    20101 aaaaaatgat tgttttttca ttgattattg gacttagcgt aggcatcata ggcgccgttt
    20161 ttcttgccca aaaaatgaaa aaagtactgc ttggacttga accacaagaa atagcagaac
    20221 agttaagtga aaaaacgatt atcgaaaatg aagtagatga aggaatctta gccatctctt
    20281 ctgataaaac tatcctcttg atcaatacac ctgcaaaaaa cattttctac caaacagagc
    20341 agctattgga tttcgaagta ggaaaaaaat cagtgataat ctatatgacg ttttgtttaa
    20401 agagacgatt gagcatcaaa cgaccgttcg gactcaatcc atgtatttaa atgggataga
    20461 aactatttct agcgttacac ctctttttag caatgaccgt tttttaggag cagtcgcaac
    20521 tttacgaaat cgatcagaag taatgaaatt aatggaggag cttgggggga cgaaacaata
    20581 tataaactcc atgagagctc aaacccatga attcatgaat aaacttcatg tcatttctgg
    20641 tttgattgat ttgaagaagt atgaagaagt cacccatttt atccagcagc taaatcaaaa
    20701 ttataaaaaa gagattggcc aagtctcaag tctgatcaaa gtacctgcaa ttgccggttt
    20761 tttattaggc aaaataaacg aagccaaaga acaatctgtt gaaatgctgt tagaaagcga
    20821 ttcttttatc cctaaaatgg agatggatga ctccatccat tcacttttgc aagtgttagg
    20881 gaacttactt gataatgcaa aagaagccgt gctacaaaaa catgaaagaa acggacaggt
    20941 ccggattcat ttaaactatg acacagaagc tgaagtattc atcgtgaccg tctgcgatga
    21001 cggtgtcggg atatcagaag aaatctcaga aaaaatattt acgctaggtt tttcgacgaa
    21061 gggaatcaat cgtgggtttg gattgaatct catccattca atcgtcaaac gccacggtgg
    21121 atttttagaa ttttccaaac aaacaaatgg cggtacaatc gtctatctag aattaccaaa
    21181 aaaggaagat caaaatgatg acaaatgtcc tgataatcga agatgatcca atggttgcag
    21241 aattgaatcg tacttttgtg gaaagcatcc ctaatatgaa cgtaatcgaa agtttcagaa
    21301 atgtagaaga aggaaaaaaa tatttcagac aaaaaaacgc agatctgctg ctgcttgatg
    21361 tatacatgcc tggcgaaagt ggtatccatt ttttatcttg gcttagacag caaggaaatg
    21421 atatcccagt gattttgatc actgctgcag atgatatcga aaccataaag aatgtgatcc
    21481 gctacggtgc cttagattat ttgatcaaac cgttcacttt gcaacgtttt cagctggcga
    21541 tcgaaaagta tcttgctttc tctcagacaa tccaaacgac tgaaaaagcc gatcagaaat
    21601 tgatcgatca agtattcaac cacaccactc ccattcacga aataccatca ttcatcgatt
    21661 tgcctaaagg tctgtcaaaa ctgactttaa aaaaaataag tgcatttatt ctaaaagaag
    21721 atactatttt ttcaacaaaa gaactggctc aaaaaagctc actgtcacgt atatccgtca
    21781 agaaatattt gaatttttta gtagaacaag atatattgaa cgaaagaatc aaatatttgg
    21841 aaatcggccg gccgctaacc tgttatgaat tgacaaagaa tgggcggaaa aagctcacag
    21901 attactgttg agtcatcgaa ttatcccata caaaatagtc caagtataca gaagtaacaa
    21961 ctgtttactt ggactatttt taaacatttt attgacgaat atccatgttt tcttatctta
    22021 attgacgggc tttaggaaga gatacctcat ttttcgtttt tccagtttct attatttcac
    22081 gaaagttctc gaaacttgtc gaaatcatat ttgataatgc ctcatctgta tttgaaccta
    22141 catgcggggt tacaagaact ctagggtaca tttctactaa ttgctggata gcagggtctg
    22201 gaatcgtctc ccatggcttg aaggatcgga aaaaaacctc tgtttcattt gcaaaaacat
    22261 cggttgcaaa accagctaaa tgattgcttt tcaaagctct taaaatagct tcattatctt
    22321 gaagctctcc acgggctgta ttaatcaaga tgctaccttt tttcatttga gctaaaaatc
    22381 cttcattgat catttgatcg ttttcacctg ggatatgagg tacatgaata ctgacaatat
    22441 cgcttttggc taataactct tcaagcgagt ggaacgtcaa tactttttta gcagcttctg
    22501 tctgatgaat atcgtagccg atcactttgg ctcctagtcc cttaaacaaa acagcttccg
    22561 tcaaccctat cctgcctgtt cctatgatcc ctactgtgca atttctgatt tcacgactaa
    22621 acatttgctc atccactcga aaatctttga aagatgttcg gatcgtcgta tacgcagtat
    22681 ttctcaaaag catcatggca aaagtcaaag ataactctgc tatcgcattt ggcgaatacg
    22741 atggtacacg ggctactgtc ataccaaaat cagctgccgc ttgtagatcg atatgattga
    22801 ctcccacagt ccgtgtaaaa acataacgaa tcccatattc ctgcattttt gcaagattgg
    22861 tctcatctgc tatacaattt cccctcaaca atacagcatc atggtccttt gctgacacga
    22921 tattgtcatg tgtcaacagt tcttcataaa gactgagatc ataatggtaa atattcaatt
    22981 tttcaaaaaa atctatctcg ttcggacgaa caccgtaaca tgcgattctc atactttctt
    23041 cctccatttc ttatgaaaat aaacctatgc catgaatcat ttgtaataca acgatccata
    23101 caggtgtcag taccacagca aaaatagttg acagtaagga tgcattggag gctaaaagtg
    23161 cctccctatc aaaactgata gcataggctg ctgccactgt tgcagctggt gtagccatca
    23221 tgataacgat tgttgccagt gcttcaaaat tgactggtag aatattcgtt gccgtcaaaa
    23281 ctgctagaat cacgatattc aatgcaggta caaataccac tttgactaga ctgtaatacc
    23341 atgaagtttt ttcagatgca gcttttttga agcttacttc acctaatgtt gcgccgattg
    23401 ctagccacgc caatggtgaa cttaaaccag ctaaataatc catcggctga aatagccacg
    23461 gtgcagtctg gtcaattcgc aaaaacgcta cttggcttat ctctccttct gcacctgtaa
    23521 ctgacacttg tggcagatac ccttggaaca gccaaatgaa aaggccggca aaagtagcga
    23581 taatgattgg attgacgaac atcgctttga tatttttagc ttccatcttc aagccactca
    23641 tttttatgta tccataagaa tacaaaaaga ttcggtagcc aatattgaaa attgaggaat
    23701 acatcacgcc gacaggacca taaatcgcac tgacgatagg cgttccgaaa aaggtcgtag
    23761 aaccaaagat cgtcaggaca cgcaacgttg tttgcttatc ccctttatag cttaagaaaa
    23821 aaggttttga aactagaata agaataatat aaataactaa tccccaaatc aagacattga
    23881 ttccttgcat cagtaattct gtattgatat cttgcatgaa agctcgaaat gccagtgctg
    23941 gcaaagccac tgttaagacg actttcgata gaatttttcc aacagattca gaaaaaatcc
    24001 ccttttttct acaaacaaac cctaataata taataaaaac tgttgaagtg attgcactga
    24061 caatcgacat atctgtcaaa gtcgatcgaa aaatgtcaaa taagttcatc tttctcctcc
    24121 taattatgtt catttattca caataaaaaa agcttttatt ttgctaatac gtattaacat
    24181 ttttaatttt atctttacat tgttacttat tgaacaatag gaaattaaag aaacttttga
    24241 aacttatgta aagtgatt
//
LOCUS       DACCVZ010000039        23909 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.039, whole genome shotgun sequence.
ACCESSION   DACCVZ010000039 DACCVZ010000000
VERSION     DACCVZ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23909
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.039"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            144..542
                     /locus_tag="IVW63_001576"
     CDS             144..542
                     /locus_tag="IVW63_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAP7859855.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            526..1221
                     /locus_tag="IVW63_001577"
     CDS             526..1221
                     /locus_tag="IVW63_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAP7859856.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1815..2702)
                     /locus_tag="IVW63_001578"
     CDS             complement(1815..2702)
                     /locus_tag="IVW63_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAP7859857.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2887..3726
                     /locus_tag="IVW63_001579"
     CDS             2887..3726
                     /locus_tag="IVW63_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP7859858.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3922..4896
                     /gene="sgrA"
                     /locus_tag="IVW63_001580"
     CDS             3922..4896
                     /gene="sgrA"
                     /locus_tag="IVW63_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HAP7859859.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5194..5550
                     /locus_tag="IVW63_001581"
     CDS             5194..5550
                     /locus_tag="IVW63_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859860.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5553..6710
                     /locus_tag="IVW63_001582"
     CDS             5553..6710
                     /locus_tag="IVW63_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859861.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6736..7176)
                     /locus_tag="IVW63_001583"
     CDS             complement(6736..7176)
                     /locus_tag="IVW63_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP7859862.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7336..7842
                     /locus_tag="IVW63_001584"
     CDS             7336..7842
                     /locus_tag="IVW63_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP7859863.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            8010..9923
                     /locus_tag="IVW63_001585"
     CDS             8010..9923
                     /locus_tag="IVW63_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAP7859864.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9928..10929
                     /locus_tag="IVW63_001586"
     CDS             9928..10929
                     /locus_tag="IVW63_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP7859865.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11131..11337)
                     /locus_tag="IVW63_001587"
     CDS             complement(11131..11337)
                     /locus_tag="IVW63_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAP7859866.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11983..12831)
                     /locus_tag="IVW63_001588"
     CDS             complement(11983..12831)
                     /locus_tag="IVW63_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP7859867.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12995..13897
                     /gene="gnd"
                     /locus_tag="IVW63_001589"
     CDS             12995..13897
                     /gene="gnd"
                     /locus_tag="IVW63_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HAP7859868.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            13899..14900
                     /locus_tag="IVW63_001590"
     CDS             13899..14900
                     /locus_tag="IVW63_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAP7859869.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14897..15181
                     /locus_tag="IVW63_001591"
     CDS             14897..15181
                     /locus_tag="IVW63_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP7859870.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15214..16011
                     /locus_tag="IVW63_001592"
     CDS             15214..16011
                     /locus_tag="IVW63_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP7859871.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            16025..16858
                     /locus_tag="IVW63_001593"
     CDS             16025..16858
                     /locus_tag="IVW63_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7859872.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16876..17733
                     /locus_tag="IVW63_001594"
     CDS             16876..17733
                     /locus_tag="IVW63_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP7859873.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17755..18264
                     /locus_tag="IVW63_001595"
     CDS             17755..18264
                     /locus_tag="IVW63_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7859874.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18301..18702
                     /locus_tag="IVW63_001596"
     CDS             18301..18702
                     /locus_tag="IVW63_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859875.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18814..19167
                     /locus_tag="IVW63_001597"
     CDS             18814..19167
                     /locus_tag="IVW63_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859876.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19201..19644
                     /locus_tag="IVW63_001598"
     CDS             19201..19644
                     /locus_tag="IVW63_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP7859877.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19661..20746
                     /gene="uxuA"
                     /locus_tag="IVW63_001599"
     CDS             19661..20746
                     /gene="uxuA"
                     /locus_tag="IVW63_001599"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAP7859878.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20739..21452
                     /locus_tag="IVW63_001600"
     CDS             20739..21452
                     /locus_tag="IVW63_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP7859879.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            22204..22404
                     /locus_tag="IVW63_001601"
     CDS             22204..22404
                     /locus_tag="IVW63_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP7859880.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            complement(22508..23809)
                     /locus_tag="IVW63_001602"
     CDS             complement(22508..23809)
                     /locus_tag="IVW63_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP7859881.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         8160 a         3716 c         4937 g         7096 t
ORIGIN      
        1 tccatacatc cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat
       61 gtgttattca ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg
      121 atattttacg aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta
      181 tagaagcaga agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg
      241 aaacattaac agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt
      301 gtgatatgaa gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg
      361 tccaaactaa tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc
      421 cggaacttcc aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga
      481 caatcattaa aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt
      541 gatacagcaa atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta
      601 acaacaaatc ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa
      661 gaaatcaaaa aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa
      721 gaagaaatga tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc
      781 aaggtgccgg tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat
      841 ttgattaccg gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga
      901 gcagattata ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa
      961 gtgattgatt cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca
     1021 gctagtttca aaaattgtga acaagtcact acagccattc gatctggagc tcatgcgata
     1081 acgttaggta aagagctact agatcaagta ttagagatgc cctcgattga taaagcagtg
     1141 aggggcttcc aagaagattg ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa
     1201 aaggtcgctg attacttctg aatcaatttc tccataaaat aaacgatagc cttctcgaaa
     1261 actcgaggag gctatctgac gattcaatat tcattaattt aaagtttggg tgactattac
     1321 taactattac ttatttctca tttaaacgat gtattcccta acctctaata catccttgta
     1381 actctgaagt tacgccagtt ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata
     1441 aaaatatctt tcgtgtttct ctagtataac agaataagaa gaacaagtcc agaagggata
     1501 tttttagtct tttttaaaat aacttttcag tcgagtttga gtttatgata gttgtttttg
     1561 aagcgatacg gcaagtgaaa aaatagggaa gcatgaaaga atctacttaa tggcgcattg
     1621 attcatgtga tagaaataaa aaactttttt aaattatatc ctcatgattg taacaaatcc
     1681 agtgatttgt tttggtacaa ataaaaaaag gccccgatga agttgtggca aaagtggttt
     1741 gcctcaaaaa taagaaggaa tttccaaaaa tcacttctca aattttgcca catccccaat
     1801 tgggtcaaat ttgtttattt gaatatattt tttacataag gatctttaat agttacattg
     1861 tcttttttca tcactttacg gattgtttta tccatgaatt ccgtatcaag agtttttgct
     1921 tcggtagcaa ttttttctag ctcagatttg tatttgtctt tattagaacc tttatcctgt
     1981 ttttttacca tttttactag ataatagctt tgctgataag tcgttggatc tgttacagga
     2041 atgatatcag aaacttcccc gttttttagt ttaaatgctg ctttttttac ttcagtagga
     2101 atctctggat tggttgaatc aaaattcatt tttccatcag tttcctttaa tgttttattt
     2161 tttccataag cttgaacaag cttggagaaa ttttctcctt catttgcttc tttttttgct
     2221 ttatctgctt cttctttagt cgaaaataga atgatctgtg tactaacttc tggatagaat
     2281 tctttccaag cagtgtctag atctttatct gttaatttta cattggcttt caaaccgtat
     2341 tggaaagcca gcatctgttt aaagagtttc ttatatgtct cttctgtttg gccaactgct
     2401 tttaattgtt ccttgtagtt tggaccgagt tttttgattt gttcattata ttcttttgtt
     2461 acttcctttg aagaaatctc ttttccgtat acatcatcaa atgctttgaa gacaatcatt
     2521 ttttttaata gtgtttgatt atttgattta acttttgggt tatcataaaa atcctgaact
     2581 gtaagtgttc cacctttaaa cgttgcaatc gtttcattgg acttgctaca acctgagaat
     2641 agtaaaattg cacatgctga aaggcacata attagtagtt gttttttcaa aaaatttccc
     2701 atcctttcct tattaaaaac agtctaacag aagaattagg gagacagtct ttcattttcg
     2761 taaggttgct gtagatattc ttagttcgta aaaatctatt ctctctatga tggagaacat
     2821 ttacatagtt ttcacgagac aagaaagaaa agggttgtta aacttaatat aaaggaggga
     2881 tgaaagatga tcaggattat tcggttgatt ggatctgttt taatagtctt agttggtttt
     2941 gttttaggaa ttcttgtcaa taatgcactt gcggatatgt ttattggaaa tagtgaatgg
     3001 attggagcaa ttgccggtac ggtcggacat ttagctgttt ttttactagc tttatttctt
     3061 gctagtaagg tcgaaggaaa aagaatagaa gattatggtg tttctgttcg aggaaaagac
     3121 tgggggtatt tagcgggagg tctcgttgtt ggaattggag tgtttctgct tattactagt
     3181 ccattatatt tgacgggggc gtatcggtta gattcaggaa acgcaaacat tgtgccgctg
     3241 ataacgagtt ttattttatt tattgcagtg ggggcatcag aagagctttt attccgtggc
     3301 ttttttcagc atcagatgct tagatttggt ccgttaatag caatgattgg atctgctgca
     3361 ttatttgctc ttttgcacgg attgaatcct aacatgacat ttctggcagt tttcaatatc
     3421 tttttagcag gttgcttttt cagcgcactt atctacagta caggaagttt atttacggct
     3481 attggtgctc atattacttg gaattggaca caaggagcta ttttgggtat accagtcagc
     3541 ggaacgcaag aacaaggttt tttctccact ctgatccaat cgcaaaatac aataattact
     3601 gggggaaact ttggggctga agcatctata tcaactacat tattcttgtt agtcttgatt
     3661 gttggtttgt tactctatgc atataaaaca aagcggatga agaaatacac tgctgtttat
     3721 caataaaaga tgaagaaagc aaggctgata tcggtcttgc ttttttaagt ctgtcattga
     3781 ttaaacgaaa aagtaaacaa attcaagcga atacacgaca tcttttgtta gattttcaca
     3841 actgactgtc gtgttctcat cattttcatt ttatataatt cctttatcaa atagaaggta
     3901 attatatgga gagtgataga aatgaagaaa acagcgaccg tattatttgt tattcttggg
     3961 ctgagtataa ttgcagcaat gattggaatc agtacttctg caaatgaacg ggcaaatgag
     4021 aatctttcat ttactgtgaa aactgatcgg attgtttatg acatgacaca acaagtcatt
     4081 actattccag tcaaaccaaa caaaagcgtg aatgctagtg atgtacatgc tgttctaaca
     4141 tatggttggg atggtaatgg aagttcagaa aaagttattg gggaagttta tttaaaagac
     4201 gtacaatgga ccgctggtat tgagtataca ataatgattt ctgcagaact atcgattgat
     4261 gagatcaaga gtaaagataa agttgatttg attgtttttt atgatggaca gatgacgatc
     4321 acggagaatt tgaaaccaag cagttggaca gttgttggac cgccaagcag tacggatagc
     4381 acaagtagtg aaagcagtac agaaaacacg agcggtgaaa gcagtacaga gagtacgagc
     4441 agtgaaagta gcacagaaaa cacgagcagc gaaagcagta cggagagtac gagtagtgaa
     4501 agtagcacag gaagcacgag cagcgaaagc agtacggaga gtacgagtag tgaaagtagc
     4561 acaggaagca tgagtagtga gagtagcaca ggaagcacga gcagcgaaag cagcacagga
     4621 aaagtaaata atgaacttga tttggtacct atcataccaa ctaaggaaca aaagagaaat
     4681 gcagggagca acctaaaaag tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat
     4741 catcaagaaa aagcgaaaga aacagataat agaaaaagcg atttaccaga aactggtagt
     4801 agaaccttga acaagctaat tacatggatg ggtgtgttac tcattttgat tgtaggagca
     4861 agctattttc gttctctctt ccatcgagtg aaataaagaa taaaagcaac agatctaaaa
     4921 ttgaataaaa cgatagattt ttgagtgaat atttcattcg agagtgctgt attgcctggc
     4981 gaagttgtag ctttgccaga tctatttttg tttactaaca tatttgagaa acaggaaata
     5041 acaggaacac aaatggaaaa taagagcaag aataattgac aatgcacact gcgcatggta
     5101 gtatctctga aaaatcagta acgaatctat ttgtacgtta ttcatgtagc tgtcggaata
     5161 agtctaaata atagataaaa aggagtatgt actttgtttg aagaatttat tgatatcaat
     5221 gaaaggcaag tatatcaatt tttgaactat tgttatgaaa gagacgagaa attatatgtg
     5281 gtgaaggata tcgctttaga tctaaactac accctggcta agatgaattc ggtgattcaa
     5341 caagcagaat cgttttgcga aaggtatcca gaatataaat tatcttttct ttcagaaaac
     5401 aagatgataa aagtcgagtt ttcttctcag tttttactga gtaaagttta ttctatactt
     5461 ttagagggaa cgattggtta tattttactg gattcacttt acaaaggtac ttatcaatcc
     5521 ttagaaaatc ttagtcaaaa aattatataa gtttgcgtac gattcaaaga aaattaagag
     5581 aacttaatac tattttgaaa aactatcatt tatcttgcag cttgaaaaaa ggtaatccga
     5641 tagaaggaga agaataccgt atccgatact tttttcactt gatgtattgg cagtcattcg
     5701 acgaaaatca ttctgatata ttatcaagta taaaaaataa acgtcaacta ttagaaaaat
     5761 ttgcgaaaca tgcgccatat acgcgtagta tagatagaaa gaaatggatc agcctactaa
     5821 gaatttcgtt gcaacgaatg aaacaaggcc actcgattac gtatgtccca gaagagatga
     5881 acaaatttgt gcatccattg ataacaaaag aagagtttac gcattacata ctagagcctt
     5941 tttttgaagc aaacttctgg tcgatgaatc acatcactcc aacagagcaa gcttaccttt
     6001 attttatgtt tggtgtaatg aacacctatt tggaagaaga tttgttggat actccagata
     6061 aagtacaaga aagttggggc tggattgaat cgtctattgt agaaaatttt gaaaaaaact
     6121 tcaagatttg ttttacaact tcagaaaaaa attatctata tgtcaatttg gcaatgatcc
     6181 atttgtattc aagggttttt gggacaaaaa agaaggtgga tgcttttgga aaatcagcag
     6241 aagacagaga ttttcagcat atatttccag tgatgtatcc aatcatgcaa cagtttttta
     6301 gtggggtagc tcgcagaatt ccagagctta atacttatta tgaaaagaac agacggttga
     6361 tttttcaata ctgtatgtta gtcagggata tttttataaa acacgaacaa cctgtcatat
     6421 tctatattca atcaaagtat ggtaaaacac aggaattatg ggcaaagaaa aggatattat
     6481 ctatgactga acgcccaata aaatatagtg catccgctga tcagttacct gatattgtca
     6541 ttagcgatta tcctatcgac aaaaaggcat atgatcaaac gaatacacag atattttact
     6601 ggaatggaca acctacaaaa aatgattggg cgcgtctgaa agctgaaatc ataaaaatca
     6661 ggaatgagaa aaatagatcc atattggaaa aattggattt cgttaattaa gaaaagcaga
     6721 ttgtttatgc caaaattaag acattgcaaa aagattattt tctttaaaat cgacaagatg
     6781 accagaaagc aagagttcgt tgagctcttg ctttctttta gttttagaaa ggaacatcct
     6841 gattttatct tcgctaaatc cagtcaaaag ttttgcagat tggtcgtaga taatcggttt
     6901 tttcaataaa gaaggggatg tacgaatctc aatatatagt tcactcaaac tgagttcatc
     6961 tattctgtga acaagatttt tataactaat agaatgagta gagagcattt cggtcacgcc
     7021 gttgtttgtc aattttagta agtggataaa ttcatttttg gttagtggtt gacgaattaa
     7081 gttctgttcg ataaacggta tatcatggac gataagccaa cgttttgcgc gtcttgaaga
     7141 cgagcagcca gaacctgtat acaatttaat catcatacat tcctccaata gctaagtatt
     7201 tatgaaataa taacatgaag aaatagtcga aaagtgccat ttagaggtgt aaaataagaa
     7261 aatgttgtca cgtataatgg aactagctag ataagaaata ctattaaatc aagaaaaaag
     7321 aaagaaggca caagtatgtc aaacacagcc gacgcaatag tagtgatcga tttacaaaaa
     7381 ggggtatgtt ttgattcttc gccgatacac gaattagaaa cagtgacagc attagtgaat
     7441 aaaagaatca aaacatacga aacgattggg aaaccagtta ttttcgttca acacgaagat
     7501 gctcaattag tgccacaaac aaaaccatgg gagctattgt cggaattatc tattcctgag
     7561 cacagttatt ttgtgagaaa aacccatgcg aattcatttt ataagactaa tttgagtgtt
     7621 ttattaactg aattggactg tcattcgatc gaattatgtg gggcacaagc agagtattgt
     7681 atagatacga ctgtgaagtt tgctcatgga ttaggatacc agcttatgat gtgtagagga
     7741 gcaacgacaa cttatgataa tccttttatg aaagcaaagg aaacaatcgc tttttacgag
     7801 aaaatttggg ataaacgatt tctgacattt ttggagcaat aagttgtttc ttcgtttaaa
     7861 aaaagcagaa tggatactgg tttatccatt ctgctttatt acgtaaaatg agaaaataat
     7921 cctgttctat ttttatggga taaaccattt attttttgta taaaaaatgt ttgcgtttac
     7981 atataattct cctagaaaca taaaaaggag tgaatagctt gagaacaaaa caagtattaa
     8041 agggagcgtt ggtcatctta tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg
     8101 gagagagcat ttcttccgaa tcggaatctc gggaggtaga aaccacagaa actactgatg
     8161 ctggaaatga aacgaaatcg agtacttcac aaacagaaac aaatactgaa acaacggttg
     8221 agacatctgt tactagcaca gatcaagaaa cgaccgctac cacagataac caacaaacag
     8281 aagaagcaac agctacaaaa atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca
     8341 aagagaatgg gacagaaaat gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat
     8401 atttgaatta cttcggtaaa cagatgacag aaatacttaa tggaccaaca gaagacatca
     8461 agtcaaaatt aatagagtta ttagtcactg agcttgctgt taatgattat ggtgtagata
     8521 aagagattat caaacatctg attgctactt atctattgta cgatatcgct tttgcaaaaa
     8581 acagtgtgtt gatgtcgatg cttggaggta cagatgatgg gacaacgcct acagaaaaca
     8641 caggcttcta tccaaataca aaacaacttc atcaaactgt actaaacaaa caagatggca
     8701 aaatgatgga tgtatatgca tattatgtcg atcaaggttc agataaaaca gtcatgatcc
     8761 atggcggatt tcgagggaat tggaataacg ggatcgttac agaagaatac aatgattttt
     8821 ataaggccgg gtataattta ttatttgttg attccagagc gactggtaat agcggaggcg
     8881 attatgtgac ctatggacaa tatgagtcag atgacgtcct ttactggata aatcaagaag
     8941 ttcgagagcg gccatctcaa aagattttac tttatggtgg ttcgatggga gcagctacga
     9001 tgatgtctgt attagcgaaa gatattcctg tcaatgtcaa aggaattatt gaaaattgcg
     9061 gatttgcatc aattgatgaa caactacgtt ttacgtacag ccagacagta gcccccgcac
     9121 taccggatgc cataaaaaat cagttagaca tcattgggga tcaagagcat gaagatttat
     9181 ttatgggcct tttgaaacaa tactattttg atcaggagat gcatttggat acaaaagctg
     9241 ctctacctac gattggaatg tcagattcat tgcctaaatt gattatccat ggaacagcag
     9301 atgatgtagt acctgtgtct aacgcgcaaa aattatatga gttatcagga gggtataaag
     9361 atcttttatt agtagaagga gcagggcatg gaaaggcaca ggaagttgac catgctgcct
     9421 acacgaaaca tgtaacggac tttttgaaag tagtgttcca tgatcagata aacgtaaagt
     9481 atgtggatga aaacaataaa agtctactca aagaccagga cgaaatccag ctttacggag
     9541 cttatggaga aaattatatg acagagcaaa agacattcga aggatacgaa ttagcaaatg
     9601 ttgaaggacc gactgaaggg atttttaatg agacgatacc aactattatt ttctattaca
     9661 aaaaaatccc agtagctcca ccaaaaaagc aagatccgac agagaatgca gacaataagg
     9721 gaaagaatga acctcgagag gatcaatcaa gtgatgatac gcaaccgatt cagatgacag
     9781 tgaaagtaca aaaaaagaca gatgcaaaaa aaagaatgtt gccgaaaact ggagaaaaga
     9841 aacattcgct tctcatttat tcaggtggat ttttatctgt tagcacgatt atcacatgga
     9901 tttggcgaag aaagagaggg taaatgaatg aaatggttca agcgaatagt gattgcagta
     9961 ccagttatca tcgtagttat tttagtcact gtatttttga ttaatcaaat cacaccaaag
    10021 ccgattagct tgcttgttag aaaacaattt gacacaagtg aaaaagaaca agtatatgcc
    10081 cgaccagatg atttccagca aaaaatcgaa caaatcgata taaaaaaaga aatatcctat
    10141 ccttcaaagt acaaaaataa taatatggat atctacacac cgaaagtgga aaagaaaaaa
    10201 ttaccgattc ttttctggat gcatggaggc gcatatgtag gaggggataa aaatgattgt
    10261 cgtgattatt tggaatatct atgttcagac acgcagcaaa tcatcgtaaa tatagattat
    10321 gaacgatcac cggaagcaaa acatcctaca ccagttatcc aattgaacga agccattcaa
    10381 gcagctaaaa aagagataaa agatcaagca gattggtcga atatttcgat tggtggaaat
    10441 tcggcaggtg cacaaattag tggagaatat ttgttagcac ttcaaaatga agaaattaaa
    10501 aaagctgatc atcttgatcc gactttggag aacaagcaga ttacgaagtt tatttctttg
    10561 tctggtctgt tggatccttc tgcacttact caagtaagtg ataaaatctc tagctttctt
    10621 tatgaaaaat gtggatgggc ttactttgat aataaggact ttgaacaatc agagaaggtc
    10681 aaaagtttag ccttggtcag acatgcggat cgttggacgc aaaacacatt cttaacggat
    10741 ggaaatacaa atacgtttac gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg
    10801 ggggtgaaag tcacaaaagt agattatgcg gagaaaaatg ctgttttgaa ccatgaatat
    10861 cagtttgatt tcagcaataa acaagcgcaa gaaacatatc aaaagttagt aatgtttttc
    10921 aaggagtaaa gtcttatgat gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca
    10981 aggagcaatt tcaataaaca agcttttcat ggtttatgaa tattgtaact tgtgactgag
    11041 gagttagaga tggcaagggg caccttttat tcgaaatttg ggaatatcac acgattattg
    11101 tcacgatctc ttttacgtaa attttataag tcagatttgt tgttttgatc gtttaaaaaa
    11161 agcaacaaat ccgaagcctg cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa
    11221 gaatgctggt tccactaata ttccgttgtt attgatataa ggctgggaac aaagatgaat
    11281 agcaaataaa atcaatgcac tagcgaaaaa aagcaaagaa atatggatag ctttcataag
    11341 cagcacctcc ttttttataa ttgtatgata aatagattaa gaatctataa atgtgacaag
    11401 tttgttagga tgtgaataaa atgatcatct agcgaacttg aaacaaagat ggctaatgat
    11461 aagcaattaa tgattcagca atcagatagg tacaaagttt accatcatac gtctagacca
    11521 ataatagaaa atatgggaat ataatagaaa agatttagga tacccccaaa agaatttccc
    11581 caaaaattcg atgtatccta aactttttta ttttacataa caatcatatc aactgtgaaa
    11641 taaaattaca aatgataacc taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt
    11701 aattcaccaa aatttttttt aattttttag aaaataagaa acaaaaataa taaaaaaaag
    11761 aaaagataaa ttttttacta ctgtatacta actttgttat cgcatctaac aagtaactcg
    11821 aataatacca atacaacctt ctccaaagat gcgatgacat acgttctaac ccaccgacta
    11881 ttgatgttct gtaccaccct tgcagaacca aaaaagccac taccaaatat ttggtagtgg
    11941 ctttttttgt tttatggatt tttcgctttt tctgttatgg tgctattctt tgatttcaga
    12001 aatagtatgt cgaactttag cgatagaacg acgtgattct ttttcgttgt aaaacatcaa
    12061 aatcacatat agagagtcca aaatgcttag ttgagaaata cgggaagcta aagcttcaga
    12121 tcggaattct gtttcttcag aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga
    12181 agaattagct tggctagtaa taacgattgt ttttgctcca gtttttctta cggtttcagc
    12241 aatatggatt gtttcttttg attgccctgt gtgagaaatc aaaacagcac agtctttttc
    12301 cgtcaataaa gaagcttcca tcaattgaat atggtaatcc gtgctgtgag aagttgcgat
    12361 aggggaacgc aaaaatttat gataagcgtc agttgctaca atctctgaac cgccaacacc
    12421 gaaaaaatag acacgtttag attcattgat aatagtagcc gcttttttta gatccttttg
    12481 ttgtaacaac ttttttgtgt catttaaagt tgaaatacta gactcgaaca ccttttgcgc
    12541 catagtgagc tcagtatctg ttttctgaat attttcgtgg atagaaatag cagatagatc
    12601 attttcttgg atcaacatgg ccattttaaa atctttaaat ccattataac caagtttttt
    12661 tgtaaattga aaaaaagtag agtcagcaat gcccagttca cttgctaaat tgctaatagg
    12721 actatgactt actttgcttg gattttctaa aatataatcg gcgatagcct gttcttttgg
    12781 gctgaagtcg ttgtacattg ttttgatttg tagtcttatg gagacgctca tgagaattcc
    12841 tcattttcat aataagatta tcattttttc cgttctcatt aatgttaaag atacaaggag
    12901 agtaggaaaa aatcaaacaa aaaatatttt tgtaaaatct atttacaaaa aaattttttt
    12961 gtataatgag ggtataagaa atggaggcgc tatcatggaa attggtgtaa ttggtttggg
    13021 aaaaatggga ttgaatttag ctttaaactt aaaagagcac catcacaaag tacaaggact
    13081 cgacatttca agtacagctg ttagtcaggc aagagaaaat gacattcctg cttatcaaga
    13141 gatctctgaa tttctagcta cttttgagca gaaaaaaatc atctggttaa tgcttcctgc
    13201 tggagagata accgaaaaca tgttaagaaa actttttcca aaactcggac caggagacat
    13261 tattattgaa ggcggaaact cttattataa agattcaatc cgtcgagcag aagagtttca
    13321 gaaaaatgaa atcggttact tggattgtgg gacttctgga ggaatcgaag gagcacgaca
    13381 tcaagcctgc ttaatgattg gaggagataa agaaactttt ctatccgtgg aacaattatt
    13441 caaagatgta gcaattgaaa gaggatatct gtatgctggt gcatccggaa gcggacactt
    13501 cttgaaaatg atccataatg gaatcgaata tggaatgatg caagcaatcg gtgaaggatt
    13561 ccaacttgta caaaaaagtg agtatgcttt tgacttggaa caagtcgcac gtgtttggaa
    13621 tcatggttcg gtgattcgcg gctggctgat ggaaatcatg gaagatcagt taaacgaaca
    13681 tcccaattta agtaattatc ggggaatcgt ttctgcatca ggtgaagcaa aatggacggt
    13741 tgaaacagcg ctagaaatgg ctgttccagt tccagtaatt gcaactagtt tgttcatgag
    13801 gaatctttca caggaagaag atagtttttc agcaaaagta gtttcagcac taagaaatgg
    13861 gtttggcgga catgaaatag ttgaaaaggg tgagtaaaat gccagattat catatagcaa
    13921 tcgttaattc cagcagtttc ggaagagtct ttccacacca cttggaaaga ttaaagtcag
    13981 ttggagacgt tcatttcttt actgttgatc aagagattcc aggaaaagaa ctagcggagt
    14041 tacttaaagg attcaatatc attattgcaa gtgttacgcc attttttcga cgagattttt
    14101 ttgaaaacaa agatgaactg ctattgattt cccgacatgg tattggttac aacaatattg
    14161 atttaaaagc agcaaaagaa caccagacaa tcgtatctat catacctgct ttagttgaac
    14221 gaaatgctgt agcagaaaat aatataacta atttgttgtc catgcttcga cgcacgacac
    14281 aagcacaagc aagagtcaag gacgatcgat gggaagatcg ggcggagttc gtcggtagga
    14341 cgctgtttaa caaaacagtt ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg
    14401 aaattttgcg taacggtttt cgctgtgatg ttctagctta tgatccttac aaatcagatt
    14461 tatacatcga aagctttggt gcaaaaaaag tagaacttca agaattactg gaacaatcag
    14521 atatcatttg tttatgtgcg aatttgacag aagagaacta tcacatgatt tctgataaag
    14581 aagtcgatca gatgaaagaa aatgtttatc tatctaatag tgcaagaggc gctctagttg
    14641 atgaagaagc gatgattaat ggtctgaaaa gcggaaagat cgcaggatat gccacagatg
    14701 ttttagaaga agaaccggga cgtcaagatc atccgtattt agcgtttgaa caagtagtga
    14761 ttacgccaca tatatcggcc tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg
    14821 tcagagatgt cgaacagatc agtcagcacc ttcttcctga acgttctgtc cagacaaaga
    14881 gcaactatat aaaaggatga tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc
    14941 tcaattttat ttatatgaag aaggtggtat ttcaaaagtt tctgatctct tgaaatcata
    15001 cggcgcgaaa agagtactgg tcacccacgg aacggtatca tgggaaaagg cgctacctaa
    15061 attagtattt ttgaatgacg aaacgattca atttttttat catcgttatt ctggagaatg
    15121 tagttatgct gaagccagac gaatagctac aatcatcaaa aaaatgaaat cgatttcgta
    15181 gttggcgttg gcggaggaaa actgaccgat ctagtgggtt atagtgccaa tcttgcaaga
    15241 atcgatttcg gagtcatccc tactttagct agtaattgtg ctccatggac acctcttgct
    15301 gtcatgtata aggagaatgg acaagcagaa gggaaaacag aacactttta cagacaagct
    15361 gcttttttta taacagatcc ccaattagtg attgattccc ctgttccata tttcattgcc
    15421 gggttagcag atacactagc aaaatggtat gaatctgagc tcatcttaga acaagatttt
    15481 ttgcaagatg aatcattttt gaagctagca caagatactg cgaagatctg caaagaagag
    15541 attttgaatc attctgctaa agcaatccaa gatatggcac aaagaaaact gacatcggag
    15601 ttcaaacagc tttcagagat tatctttgct gttgctggtt tagttggagg attaggagat
    15661 aaatacgcaa gaaatgcggc agcacatgct atgcatgacg ctatcagtaa atatattccg
    15721 gaaagccatc gttttctaca tggagaaaaa gtagcgtatg ggattttcta tcaactggca
    15781 ctagaaggtc gctgggaaaa aatagacgag ttatatcctt tgtatcggga attagaactg
    15841 ccggtttctc tagaacaaat gggattattt ccgaaagata aacagataat agataaaatg
    15901 gctgaattta ttgattcgaa agagaaagtg catttgattc ctatagaggt aacacagaaa
    15961 tcactgatac agtcaatgat ggaactggaa ggttatatca gaaagatctg aaggaggagg
    16021 acacatggaa acattaagtg tagtacaaag tttgttgatt gctttatggg tagccgcggt
    16081 tatgtcccgc tggttaggtg gaggagccac gttgacctta cgtttttctc ctttgatgac
    16141 tggattagtc gtcgggttga tcatggggga agttgcacaa gcgatgattg ttacagccgc
    16201 tttgcaaatg atttatatgg gggttttttc tccaggagga tcaatgccag ctgaaccatc
    16261 tattgcagca gctatcgcag taccagtcgc attattaggg gatctgtcgc cagaagcagc
    16321 gattgccgtt gcggtgccag tcggattgct cggaagttac ttgtatcagt ttcgtttttt
    16381 catcaatact tttttaggta aatatacaga caaagctgta gaagatttga atacaaaagc
    16441 tatggcccga tcaattattc tttatccaac ggttgcctca tttttattat tcgttccgct
    16501 tgttttcatt gctttatatt taggggcgcc attgatcgct gatgtaatca aagctttaga
    16561 gggaacagtc gttatccaca ttcttgaagt agtaggtgga gggttagcgg caatcggtat
    16621 cgcgacaact gtatacgtta tcggtcgaaa agattatctg gtctttttct tccttgctta
    16681 ttttatgagt gttgttttga aatctttaga tattacgatg gttacttatg ccatttttgg
    16741 gattattatc gctttgatct ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac
    16801 aagcaataac aattcagcat cttttgatga cgaagatgac tatgatgacg gattttaatt
    16861 taggaggaat gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc
    16921 acgaaaaaag atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac
    16981 tcttttgaac gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa
    17041 ctttataaag atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac
    17101 actcaattaa gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcaa
    17161 agagcagaag aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac
    17221 acgaaagcgg gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc
    17281 gtccaatata tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc
    17341 gcactttttc cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca
    17401 agacaagctt tcactatggg ccgtaatgct acaggcctaa tgcaaaacac tggtgttcag
    17461 acagcgattg aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac
    17521 tatgtaaaag tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag
    17581 gaaattcttg atcaaatcgt gccagggata ttacctttag ctgtcgtaat gggtgtgtac
    17641 ttgttctata cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata
    17701 ttaattgtgc tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt
    17761 gtagtcaatt tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta
    17821 tctcaaaaaa gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa
    17881 tttatgagag atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt
    17941 acaccagaga aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt
    18001 ttgatcgcaa aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa
    18061 gaattgaata ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa
    18121 tctgtttatt taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc
    18181 gtaaagaata tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta
    18241 ttgaacaagt ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa
    18301 atgaagaaga acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag
    18361 cgccgtacaa aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt
    18421 atgagaacag atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt
    18481 tatgttggag atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt
    18541 catgcattag gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac
    18601 tctatattat tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat
    18661 aacaaaaatc ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta
    18721 gcatttggga gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa
    18781 acttttattc gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat
    18841 gatccgagtg tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac
    18901 agcgtgagat cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca
    18961 gatacaccgc tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa
    19021 gttgataagt tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg
    19081 cagttcttct atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc
    19141 aatcagatta ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta
    19201 atgttggaaa tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg
    19261 gaagtaattg tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac
    19321 atccaaacat tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc
    19381 atgctagtat ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc
    19441 aatgaactga ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca
    19501 atgttgttag aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa
    19561 caaattgtca aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa
    19621 aaattagatg aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg
    19681 gtatggtgaa aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa
    19741 tgggataatt ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat
    19801 tgaggagttg aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt
    19861 agcgatccac gatgcaatca aggcagggac agatgaacga gattactata ttgataacta
    19921 tatacgaaca atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa
    19981 accaattttt ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc
    20041 tcttttatac gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat
    20101 acacagccag tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt
    20161 cgctcagctg gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac
    20221 ttatttttta gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca
    20281 tccagatgat ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga
    20341 cttgaagaaa attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg
    20401 atctttaggg gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg
    20461 catccatttt gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac
    20521 ggcacatccc tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca
    20581 agaagggttc gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc
    20641 tatgcctgga tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata
    20701 tgaggcgata agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca
    20761 tctttgatat ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa
    20821 aatcagcaca aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc
    20881 aaacagaaat ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata
    20941 tcaaatggcg agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag
    21001 tatatacgaa aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata
    21061 caatcgtggc ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc
    21121 tatatgcctt gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac
    21181 cagagatctt tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat
    21241 ttgaagactc gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca
    21301 tcaaagatca tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg
    21361 taagtttata tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac
    21421 gatttttaga aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt
    21481 atttattgtc ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag
    21541 tatctacctt atttgtagtg aacaatttag aacaaacaca aaacgcatct actgttatct
    21601 accagtagat gcgtttaaag agaagaacga gaatcgtcca tatgagggtt tccactcctt
    21661 atgcagattt ttttaattct tgcactgctt gttcgatcgt aacacctgtc gctacatgat
    21721 tggtattttc tttgtcaaaa acgacaaata gattcaaatc tgtatccaag gttactcgat
    21781 attgtatatc tttgttatag aatgtcatag ccattctcct ttctttaaat acttgctgaa
    21841 aggcaacgaa cgcgttgata acgaaattcc atttataagt ataccaccaa ttgaaaggtt
    21901 ttcatagtta agaaatttta aagtcaaaag ttgcagataa aagcaaataa acaagaaaac
    21961 aaaaagtgaa tcaatcgcgg ttattcaact ttttcttcga ttcgaagaca atagaagaca
    22021 atgaatttta tatttcattg cattatcctt gtgttattag aaaaagcatg atatattaaa
    22081 tgagtaatct attttgaaac gtaatttgag cgatatatct acatagataa aactcctttt
    22141 gcctatcaaa tatttattgc aacgaaaaaa cgtacattga tacgtatcag gaggaattta
    22201 tttatgaata acggtacagt aaaatggttc aacgcagaca aaggttttgg ctttatcact
    22261 ggtgaagatg gaaatgatgt atttgcacat ttttcagcta tccaaggtga cggcttcaaa
    22321 actttagaag aaggccaagc agtgtcttac gatgttgaag atggtcaacg tggccctcaa
    22381 gcaacaaaca ttgttaaagc ttaataaaaa ttgactttta accgtctttt cgaaagaaaa
    22441 gggctctttg tcaaatagga ctgatagagt gagataagaa catctaaggt agaattcctt
    22501 ttctacttta gatgtttttt gattcatagg taatcagatt atttagtaag aaaattctgg
    22561 tcttcatttt ccgaaagctt cgaaagccat aagcgactcg tttcaatgct ttgatgtggg
    22621 tatgcagatt ttctattttg gcatttgaat aaggcaattc gagggctaaa cgaatgccgg
    22681 attcatagtt tataaaagct ttttttatag aatgcagttc ttttggaacg gaattgggca
    22741 tcgttcttac aagtttaaag aaagtgtccg cctctttgtc gtgaaacgct tgaagaattt
    22801 cttgatagta aaaataggcg attcgtaatt cgtcagagat cgaaagcaga cgatccacca
    22861 cttcactttc ggtgagatac gcccaaccaa aattgcgcca tttggtccat ttgtcataaa
    22921 caagcttgtc ctgtcgtttg atcagaagcc gagacaacgc ctttaattgt cgataatatt
    22981 tggcttgtgt tggatcgttt cgatcaaagc ttttcatgat tcgtacgcga atatcctcaa
    23041 atttacgaat gagatgtttg acaatgtgaa aacgatccac aacgagtttt gcctttggaa
    23101 aacattcctt tatcagagag gcataagaaa cattcatgtc cgtcacgatg acctttacct
    23161 tcaatcgtgc gcgtcgttca aattgcataa aataagaaac gagagccttt ttcttccgtg
    23221 aaggaagaat atccagtaat tttccagtat cgccatccat acaagaaaag gagtagggac
    23281 cgacttgatt tttcagtgaa cgaaattcat ccattaataa acaacgcggt aaccaatttc
    23341 tttttacttt tgtcatgggg atcagagaag cgagtgtccg agaaacggtc gaccaagaaa
    23401 cgccgcaatg cttagcaatt gtcgtcattg cttgtttttc agttagctct tctaaaattt
    23461 tatagcgcac ttgtttagcg ataaagcagt ttctatcgac aatgtaggta ttcgccgtaa
    23521 aataggtgtg gcagccacga cagtggtagc gttgtttcgc taaagcaaga taagtcagtt
    23581 ggttcgcaca tttattaagt tgaatgagcg attttttctt tccgttctta acgatcatgc
    23641 cttcatgatt catctgttta cacaaaggac agcgacgaat ttctttactt aacgtcgcag
    23701 aaacaacaag actcttgata ttcttaatgc tcttcgattc cacatttgtg atgaaaatgt
    23761 ttttatcttt gattccaagt agtagtttga tatgatgaag atcaggcata cagaacgctc
    23821 ctttgattgt gttgtggtga ttcaattcta acggagcttc tgtatgtttt gttttttcat
    23881 gctcaaaagg gaccgataga atgattttc
//
LOCUS       DACCVZ010000040        23827 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.040, whole genome shotgun sequence.
ACCESSION   DACCVZ010000040 DACCVZ010000000
VERSION     DACCVZ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.040"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(53..787)
                     /locus_tag="IVW63_001603"
     CDS             complement(53..787)
                     /locus_tag="IVW63_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAP7859882.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="IVW63_001604"
     CDS             1114..1524
                     /locus_tag="IVW63_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAP7859883.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="IVW63_001605"
     CDS             1517..2218
                     /locus_tag="IVW63_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAP7859884.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="IVW63_001606"
     CDS             2218..3804
                     /locus_tag="IVW63_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP7859885.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="IVW63_001607"
     CDS             3823..4044
                     /locus_tag="IVW63_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HAP7859886.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="IVW63_001608"
     CDS             4041..4802
                     /locus_tag="IVW63_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HAP7859887.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="IVW63_001609"
     CDS             5182..5691
                     /locus_tag="IVW63_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAP7859888.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="IVW63_001610"
     CDS             complement(5766..6305)
                     /locus_tag="IVW63_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAP7859889.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="IVW63_001611"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="IVW63_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAP7859890.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7372..8169
                     /locus_tag="IVW63_001612"
     CDS             7372..8169
                     /locus_tag="IVW63_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-nitrite transporter"
                     /protein_id="HAP7859891.1"
                     /translation="MNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGT
                     AVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLA
                     LSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILV
                     EGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFAS
                     HGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD"
     gene            8197..8832
                     /locus_tag="IVW63_001613"
     CDS             8197..8832
                     /locus_tag="IVW63_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAP7859892.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="IVW63_001614"
     CDS             8852..9625
                     /locus_tag="IVW63_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7859893.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="IVW63_001615"
     CDS             10033..10830
                     /locus_tag="IVW63_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HAP7859894.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="IVW63_001616"
     CDS             10808..11221
                     /locus_tag="IVW63_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859895.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="IVW63_001617"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="IVW63_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAP7859896.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="IVW63_001618"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="IVW63_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAP7859897.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /locus_tag="IVW63_001619"
     CDS             15998..16558
                     /locus_tag="IVW63_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAP7859898.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="IVW63_001620"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="IVW63_001620"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HAP7859899.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="IVW63_001621"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="IVW63_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HAP7859900.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="IVW63_001622"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="IVW63_001622"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAP7859901.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="IVW63_001623"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="IVW63_001623"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAP7859902.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="IVW63_001624"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="IVW63_001624"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAP7859903.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="IVW63_001625"
     CDS             21905..22483
                     /locus_tag="IVW63_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAP7859904.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="IVW63_001626"
     CDS             22535..23017
                     /locus_tag="IVW63_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HAP7859905.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="IVW63_001627"
     CDS             23134..23508
                     /locus_tag="IVW63_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859906.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7780 a         4286 c         5116 g         6645 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcgtg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaca
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagtt
//
LOCUS       DACCVZ010000041        23034 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.041, whole genome shotgun sequence.
ACCESSION   DACCVZ010000041 DACCVZ010000000
VERSION     DACCVZ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.041"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..2564)
                     /locus_tag="IVW63_001628"
     CDS             complement(<1..2564)
                     /locus_tag="IVW63_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859907.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSIP"
     gene            complement(2786..3670)
                     /locus_tag="IVW63_001629"
     CDS             complement(2786..3670)
                     /locus_tag="IVW63_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAP7859908.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(3765..4202)
                     /locus_tag="IVW63_001630"
     CDS             complement(3765..4202)
                     /locus_tag="IVW63_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859909.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            complement(4419..5330)
                     /locus_tag="IVW63_001631"
     CDS             complement(4419..5330)
                     /locus_tag="IVW63_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP7859910.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(5707..6345)
                     /locus_tag="IVW63_001632"
     CDS             complement(5707..6345)
                     /locus_tag="IVW63_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7859911.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(6349..7119)
                     /locus_tag="IVW63_001633"
     CDS             complement(6349..7119)
                     /locus_tag="IVW63_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAP7859912.1"
                     /translation="MIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQE
                     ISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSTYWERNILSGEIYPPLK
                     IKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFS
                     FFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIER
                     EPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            complement(7537..7953)
                     /locus_tag="IVW63_001634"
     CDS             complement(7537..7953)
                     /locus_tag="IVW63_001634"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859913.1"
                     /translation="MMTREKEAYERFILLFVERFNQAFHTDYATNIFEDFENSYSYSV
                     ISSTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNGFSLHQVLWCLLGKKKI
                     IITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGI"
     gene            complement(8004..8385)
                     /locus_tag="IVW63_001635"
                     /pseudo
     CDS             complement(8004..8385)
                     /locus_tag="IVW63_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339091.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8511..9176
                     /locus_tag="IVW63_001636"
     CDS             8511..9176
                     /locus_tag="IVW63_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7859914.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(9573..11606)
                     /gene="brxL"
                     /locus_tag="IVW63_001637"
     CDS             complement(9573..11606)
                     /gene="brxL"
                     /locus_tag="IVW63_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HAP7859915.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
     gene            complement(11724..14246)
                     /gene="pglZ"
                     /locus_tag="IVW63_001638"
     CDS             complement(11724..14246)
                     /gene="pglZ"
                     /locus_tag="IVW63_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HAP7859916.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     FIWNSDHIEEKQKYGQLYRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMK
                     RSVKTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQ
                     LTYNEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSV
                     IYIYHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYK
                     RSHVEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPI
                     TSSIFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLS
                     TTLEFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEF
                     VNRRYTVEDTYYLVIKNQKNDLTERIKFIIDNPFAESFDFDI"
     gene            complement(14362..17994)
                     /gene="pglX"
                     /locus_tag="IVW63_001639"
     CDS             complement(14362..17994)
                     /gene="pglX"
                     /locus_tag="IVW63_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HAP7859917.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQAITKEYLGKVREYISKFNEFTNMDILYGMKEIQEKYLHILDVAEMLVDKYV
                     AVVTNPPYLNKMDKKLKKYVNDNYSDVKKDLFSVFIKLNSQMLIDNGYASFMTPFVWM
                     FISSYEKLRSFLINERNISSLIQMEYSAFEEATVPICTFTIKNSNEQDGSYIKLSDFK
                     GGMEVQKIKTLEAIHQHGECDYFYSTNQDNFKKIPGMPIAYWASDNVITDFAQGKLTN
                     DVADAKQGLATGNNNKFLRYWFEVEFNKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKW
                     YGNNEYVVNWENDGDEIKNYVNENGKLKSRPQNLNYYFKKGITWSTLSSGQVSFRLQN
                     QAIFETKGSVLFSKDITDFEEIFGYVNSKLVNHFLTFISPTLDYHEGPMGKLPFLKVT
                     SERKLKKIREKVDENIDIARKDYNALETSYEFRRNILLSYMFKKDLSEAFNCLSRQLV
                     NQFNTLKSNEEELNDIFINHYSLEKELTKEVQDEYISARLPDKAREIKDFISYSIGCI
                     FGRYSLDEDGLIFAGGEWDPSRYQKFKPDTDNVLLITDDEYFKDSQIDIVNRFIDFVE
                     ITFGKETLEENLQFIADTLGGKGTSREIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGK
                     QNGFKALMYLHRYTPDQLGKVRTEYLHELQKAYDNRIELRQQQISTSDNPKERNAMTK
                     EIVKIQKQLKEVREYDEKLGHLALKRIELDLDDGVIVNYDKLQRDPKTGEKFQIFAKG
                     VKEPKK"
     gene            complement(18058..21729)
                     /gene="brxC"
                     /locus_tag="IVW63_001640"
     CDS             complement(18058..21729)
                     /gene="brxC"
                     /locus_tag="IVW63_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HAP7859918.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLGMSGGNKFKNRYTFTYAQVLDQRPYKQAG
                     NAEMTVNFISPYSDLAGQEAELALKSSRNLLFVELPSDKEFKDDIAMYARMNLYLTTT
                     YSSVVKNFDAIRSEKSGELQELSASINDQLNELLKSAKFFYNGAEIQLTGSDFKAKFQ
                     SALQKMAEEVYHKLNQIDAPKEKEDILYLVKESKNEIIEDPSNEQAVQEIFNFINDQK
                     RNHLTITMKTIRDRFETKQPYGFTELDVEWCIAKLFMSGKIDLLYNNVQISRMDDPNS
                     IVMIIQKRRESEKIKIEPSAVISPKAKKLVDEIGRELFQSRNIVDENNNEHTMENFKK
                     YLKGQLDNLRSYFDLQNTYTYPSAYEYEQIKKYLEVIVQTSDVEDFFYTIKKYRDELF
                     DWAETYDKIKNFHKQNSTQKKIWENAQDKIRLIEKSRRQTSSQEIDQLIHEMKTILKK
                     ADPYSDMMKLNELIQEFIEQYNQLLELESQEILNKLTEEKQATFKLLEGKDFKDQFVP
                     IVDQEFQELKAKIEQANTIDDLVFLSLNVAEQYLIFNQRFDNEENRRRQEEQARKQIE
                     AANLIRETEKDEIDSAAKAEEIAIVKPTIQQKTVPMRTLNVHVKTIKSAADIDELTAE
                     INQKLKEQLQENTEITIQF"
     gene            complement(21754..22329)
                     /locus_tag="IVW63_001641"
     CDS             complement(21754..22329)
                     /locus_tag="IVW63_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HAP7859919.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            complement(22329..22928)
                     /locus_tag="IVW63_001642"
     CDS             complement(22329..22928)
                     /locus_tag="IVW63_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HAP7859920.1"
                     /translation="MNKKYSAGLVSKRFWFSEFKLYIQLRLEGYTDIEIKEKNEHENI
                     FFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLNIDNQKLVNLISILMIDDLFNEFM
                     TEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDISKWKDYTIKRLIAAYQTNLIETGL
                     VRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLALGGIL"
BASE COUNT         6993 a         4531 c         3344 g         8166 t
ORIGIN      
        1 gggatagaaa gaacaaattt acctgtatca tcaatagttg tttcggacaa aacagcttga
       61 ttttttttca atgaaaccaa agctcctgct tcgcctgtac ctgtgattga gcgagaagct
      121 gcattgatca atgtggtact taatttagca ggctcaggag gaatcacatc gactgtcgtt
      181 ttggcagagt ccagttctgt cacttcttgg ccgcctctta cttttttagc agcaactatt
      241 tgcacttgat cccccgttgt tagtctttct tcgttgggta cttgaacctc aaacaaaccg
      301 ccttgttcgc cttctcccca cggattatat cctgtccctt cattttcatc tgtttgtcct
      361 tgtgtgagag cagtaatttc tacaggtgat ttcgtcgtat ctgcataagt aatacgtaaa
      421 gtcacttcta cttcgcctgt ccaagcatct cttggctttg cctcgacacc ttcgggaaca
      481 acgacatgcc catagatttt tttatctgca ttcgttggta ctcttaagga ttcaatcatc
      541 ggaagctggt tattggcact gattcgatta taatttttca ttccggcacc tgtctgagca
      601 aattcatttg ttaaacctgc actagggctt gatacaaaat tacctaagtc ggttccattg
      661 atcgataagt ctgtcatatc agaaaaataa tccggatctt tttcaaagtt atcgaacgtt
      721 actcctgcct ttcgccataa agcaatttct gaatgagcga tcttcaaaga agaatcgcca
      781 tttccttgaa atacccagcc acctatgcca ttagtctcgc ttccgatccg tttgttttgg
      841 aaatcgaaat aggtaggaga ttctaagtct acattcaaca catccccact gatgatgcca
      901 gtcttatctt ccccagtttt cccgaccatg actaaataag ttttttcgcc agccataaag
      961 ttcaaatcaa tatctccagt tgtatctacg gtagctccgg aatctgcgcg tatatcgata
     1021 tttgattttt ctccagtaac cgtaaaatca gctgaccctg gactttctag aaaaccagaa
     1081 gcgtcataaa attggatcgc ttggtttcct tgattgagtc tgttcacata agatttgcca
     1141 tcccctgcat ttcttacctt caatgagcct ccattagtta ctgttagttt ttgcgtaccg
     1201 ttctcaaaac gaactgcgct agaacgacca ctttgcttat caatatcgat gactgatccg
     1261 gctccttcta cgatcaaaga aagtcctttc cctacaaaac gcatcccatt gtttccaggt
     1321 tggtcgccat ctccagccat tttgaccgag atttgtccac cacttgatac atggatttga
     1381 ctagaatctc cttgcaggcg aaatccgcca gtagtcgctg tattgattgt gattttccca
     1441 tcattcgaca cagcgactct tgatcctgag cctctcattt ggataattcc gcgattgttg
     1501 tcgttggtaa tattgatctt tgtatttacc gaaaattcac ttcctgagcc actgacttta
     1561 aatgtgacat tcccgggtag cgtatcgaca gcctctcctt catcgctgac gccatctgcc
     1621 cgatcatagt caagagagac ctttgaacca ctcaagatat ggagtcctgg tgctgttttt
     1681 ccactgcccg tctcatcacc tgaatctaga aaaccataga attttcctag atatggtcca
     1741 taaagctgac taccattgat tacatttagc tgatagcttc tacaaaaata agctttaccc
     1801 ggagcggcat tcatcccttc tttcactggt tggacatcca atacaccgga aacaccatct
     1861 aatgtgacag ttgcacgagg ggcgtaaatc aggcctaatt tagaaccatc atataagtca
     1921 agtgtcccgg taaattttat ttctcccgta aaatgatatc tgtttcccca aaaatcggac
     1981 atataagcaa tgataatggc atttccatcg atatttggta tcaacccacc tggatgagct
     2041 gccgttcctt taaaattctg aaactcgatc gactgaggtg tctcattgat atagatgtga
     2101 tgtgtgccga aattatgagc aagtccgcca aaatcgataa cgatatctcg cttgatctcc
     2161 aattccctgt ctaaagtcaa aggctgagtt aaacgaatct tagctactga ttcgtctgcg
     2221 agaagctgcg tcagttcttc tgttgtggca gcttcgctgt acccatccgc tgaaacaact
     2281 ctaacctgta cctcttcact gctatcagac gtttgttcag ctacttctga ggtctcactt
     2341 gtcttatttt cttcttgcct tgtattagaa gtaggcgcct cactttggga ttctgtagtt
     2401 tcagaagtaa ttgattcttc tgaaaaagta gtcttgtcaa aactttgatt ctctgattgc
     2461 gttgattcgc ttgttttctc tacatcggca aaaacggatg tcaccatcaa gagagggaag
     2521 acaaacaaaa tcgacgcaat cagctttttt acatattgat tcattctcca ccatcctctc
     2581 tgacgttttg acaattttat tttaacgttt taatttattt gtaattgtac tttcatattt
     2641 aaaatatgta tttttatggc aaatttttct gttaggtgaa aatttctttt ttgtacaaaa
     2701 aaaggctgtg acaaaagtct tgtcacagtc ccttattccg aacaaccgat gtcctcctga
     2761 caactcttcg gtcacaacct ccattttaac aataaacctg taaatgtgag ggtaacactt
     2821 tgattgtcac aggtaattta tccccttcat ctccatcaac attcgtcgtc aattcttcct
     2881 catcagctaa tgacacaact aattgctcac aagtaagata ggctagattt ttcgtagatt
     2941 catctactcc ttttaatagg tctggcaatg ttttaagcgt atcgatcaaa gaagaatctt
     3001 ttaaataaac caaatggagc ttaccatcat ccacttttgc atttggaagt aatgtttcaa
     3061 aaccgcctac tgagttagtt agtcctatca gcaagatact gctctcaatt tcttccttct
     3121 ttccatcaac ttctacgtga aacgagtagg attgtgtgga agctaactgt ttgattcctg
     3181 acatgaaata agctagtttt ccaaatttcg tcttcttctc cgcatctaca tcattgattg
     3241 cttcagggat agagccaatt gcgacgacat tcataaaata gtcgtcattt atttttccaa
     3301 tatccaatgg cttgactgat tcaatcgaaa aatgattgat cgcttcctca ggttctagcg
     3361 gtatccctaa tgctcgagcc aagtcattca ccgtacccaa tgggaaaaat ccgaaatttg
     3421 gccgatgttc ttgttcagcg attccactga ttccttcgtt gactgttcca tctccgccca
     3481 tgacaaacac actatgatac ccttccgtag ccgcttcgcg agtaaagttt tttgcatccc
     3541 ctgctttttt tgtatgcaag acgaccactt catcaaacac cgattccaat tttgctatcg
     3601 ctaattgctc aaattccttt gcttgttcac cgcctgaact ggggtttacc actaataaaa
     3661 cttttttcat cactttcttt cccttctgat tgatttcttt aatataacga tagcataaag
     3721 aaaaaaatta ggctgtgatg aagtactgtt catgaaacat tcatttattt tttgacaaga
     3781 taaaataccc atactatgaa actgaggaaa attaaaacaa tgatatagga aataaaagaa
     3841 aatgataggc attgtatacc taataaagta aaaatcttag gtggcagata aaaacacaaa
     3901 aatagcaaga gaatgtaata gcgtttcttc cactttttgt tatcagacct tatagcgatc
     3961 agaggaatac caaatgcata actgaaaaac tcttgatgta ctgttaatat gtcacgacct
     4021 tgaataataa atgcaacaat ccccgctata attagtgtgc ctaataccaa aacggaaaat
     4081 tgatgaatat attttatata caaatgatcc attgtacttc ctgccttttt atttgtgaga
     4141 aaaacaaatc cgtatacgtg aataacttct agaaataaaa gaaatttgca aaaccactcc
     4201 atttatctac ttctacgtgc attttttaat atcgttttct ttatttaaga ttatacagaa
     4261 aaatatctag ggtggctgga ttctaagtaa aaaaaatttt taaaataaaa agaactaaat
     4321 caagtaataa ttaaactact gttgatttag ttctaataaa aagatttaga tgaacagttt
     4381 tattgattta aatagttcat attttttatt tataccgctt atttactact tgctgtacta
     4441 gaatctgaag tgaatgtact caaaacattt tcaaagtctt tgtctttgat ttttacatta
     4501 gcgtctttca atacttcgcc aattacttta ttctggaagg tactgtcact taattttgtg
     4561 tctgttgcaa tttctttcaa ttcttttttg tatttatcca tgtcgttgcc tttgttttgg
     4621 tttttcacca ttttaaccac ataatattcc gtagtataag ttgaagcatt ggtagaagtg
     4681 atcacatcag aaacttgacc atctttcaac ttaaaggctg cttctttgac ttctgccgga
     4741 accgttgtag tagtggaatc aaatttcact tttccgccat cttcttttgt cgtagtatca
     4801 gttgacttgt ctttggctaa tttagagaaa tcgtctccct tatcagcagc tttcttcaca
     4861 tcttttgcat catcttcact tgctacttgg ataatttgag cttccacttc tggatggaaa
     4921 gattcccaag ccgtttttaa atcttcatcg gtcaatttga tatgtttctt tagaccttct
     4981 tgaaaggcta gactttgttt gatactgtct ttgaatgttt gttctgtgta acctgcagat
     5041 ttcaattgtg aatcaaatga atcacccaat tgtttctttg tttgatcata ttgggaatcg
     5101 atttctttgg ttgatacgtc atctccatat ttatcttcaa atacttgata aacgatcaac
     5161 tgttgcacag cggaatctgc tccttgcatt tttttcaagc tatccattac ttcttgttcg
     5221 ctgattgtac cgcctttata actaacggct gttttttcac cggcattcgt acagcctgac
     5281 aataagccag tgcctagtac gatggcaagt gctaaaaatc tttttttcat ttatcaattc
     5341 tcctactttt cgttttttgc gaattgctaa aaacaaaggt gttcaagatg aaaatcatca
     5401 agaacacctt tactaatctg ctcgatacgt cctgaataga tataaggcta cacaatccag
     5461 aaagttcgct cagcagaata aatgtcaagt agcacatcac accttaatat actacttctt
     5521 ttgttaccgt ttttcaagtc tatcttgcgt tccgtattta acgtaactaa ttcttagaac
     5581 aaatgttatc gattttgttt ttcttcttcc gctgttggga tattcaaatc agacactttt
     5641 atgttcgatt ttccagacat ttttttgttg tttttattag aaaaagtttg ttttttcatt
     5701 tgttttctaa agcatgatct tcttgtttcc tattttggtc agatatggat catgcgtgac
     5761 cacgataact aacgtacctt gggaagcctg ttgcgataag atttcaacga cttgctcctt
     5821 atttcgttta tctaatgatc cagttggttc atcggctaaa atgattttgc tattcttcaa
     5881 taagactctc gcacaggcga ttctttgctt ctcaccacca gataatgtgt agataggcgt
     5941 acttagcttc ttgtttatat ttactttttt caatgcctca tactttgctg ttcgcttatc
     6001 tgaaacattt aaattcgaaa acttcaatcc aatatctaaa ttaaaatcga ttgtttcata
     6061 ttcaatcaac ccaaaatctt gaaaaagaaa agagagggca tttcttttta tcaagcgctt
     6121 ctctcttcca gttaaatgtt ttgtttcttg attaaataaa taaaattgcc ctgaactgaa
     6181 ttgatcattc aatcctaata tattcaataa agtacttttc cctgctccgc tctctccaac
     6241 tacagtcaca aaatccccag catccgcagt gaaacgatcc aaatgaagaa tcgttttgtt
     6301 tcgaatgatt tttttcgcac cttttatcac tatcaacggc tccaattgtt aacctccatt
     6361 catcagcaat aactgacttt tcttttctgt agacaaaata aaaacaactg aaagaataaa
     6421 atcaatgaag ctaaagaaaa aaatattaaa aagatattta ggctctcttt ctataagaaa
     6481 aaggaagatt acacttgtcg ttccccattt gatgaggttc atcatgaaga aatctttata
     6541 cgtttcaaag agcgaataac cacttgaacg aaagatagcg attttccgac aattgtagac
     6601 aaaatatatg cataacatga catagctcaa caagaagaaa gaaaagaaag tgagtaaaaa
     6661 tatctgtatc aagtaatgaa atgatctgct taacactttg acagctatct cttcagtctg
     6721 agtatacgga aatgataact gcaagttatc acgtaactga ctttcttcaa tcagctcaaa
     6781 taacctttct ttcgacaaag agcctatctt gatctttaac ggtggataga tttctccgct
     6841 gagaatattt ctttcccaat acgtactgtt tttcaatgtc agtatttcaa caaccggata
     6901 atgttcgatc caggggatag aaggaataaa tgtataaatg ggttgattgt tttttataaa
     6961 tagaaatttc ggttcttttt cactgatttc ttgataatat tctgttattt gcgccaggtc
     7021 attttttaaa tctgtatgtc tatatcgttc agggatcaat ataacagggt gcgtttcttt
     7081 ttcggttatt tggatcaacc ttccagagac atcaatcaaa ggaaatttct taagataatt
     7141 cagatttatt tttatccctc tgccaaactg ttcattttct tcattcaagt aatctgatac
     7201 attgactaat atacttccgt ttttattcaa agtttcatat aattcctgat cggctgctga
     7261 tgcaaaacga ttggaataaa taaaatccac gtggtttttc ccgatggtta ctggataaaa
     7321 tacatgatag tcctcaccag cgatttcttt tggtgtttca tgggaaacag ctaactgtga
     7381 agaagaaaaa acgatagttg ctaattcgac attggcaacg gtcaaaagaa gagaaaacaa
     7441 caatccaaat gtaaaaagaa tgtattggat atagttgaac gcttctctta acgaagcgat
     7501 tttttcaact aataaaagag aaatcaaaga gataccctat attccgctga acaagaaaac
     7561 gtacatctgg aacaaataaa gaaattgctc cttataatac ataaaaataa aaccaccaat
     7621 gattcctgca attatgaatg taataatgat tttctttttc cccaataaac accacaatac
     7681 ttgatgtaat gaaaagccat tattcaacaa taaactgatt tctttattca tcaataagaa
     7741 aaaggatgat aacaaaagga ataaaagaat caatccaata gttaaataca ctcgataatt
     7801 atatacgtct gtacttgaaa taaccgaata cgaatagcta ttttcaaagt cttcaaaaat
     7861 attagtggca taatcagtgt gaaatgcttg attgaatcgt tccacaaata gtaaaatgaa
     7921 ccgttcatag gcttcttttt ctctcgtcat caagaaaaat tcaccttcaa aatcttttat
     7981 tttgatcgat tcttcaatgg acgttacgcg aaaggaggta ttagaatagg gtaccttctc
     8041 gtgagaagat ttgacatccc cttgataata caatgtcatt tcaagctttg gctgtatctt
     8101 gaagttccaa gatgtatcta cttcattgga ttcatttact gtttttttca tataagaaag
     8161 ctcagtttct gatgagacat tttcaaatac catgattagc tgctcatatt cttcttgccc
     8221 aataaaatgt tgtggcaatc gaatcggagt ataagtatct gtttgatgga aaaattcatt
     8281 tgtccgatag agtacctgtt tatttataat aaccaaggca aaaccactca tgataccggt
     8341 cactatgatt gtgagtaaaa ctgtgaactt ttttttgatt atcaccactc tcccttactt
     8401 aaatgattct ttgataaaat cataccgttt ttcatcaaaa aaacgtatct atcaaatgta
     8461 taggtcatgt agaataaatc tatatactgt agaatcgaaa ggagaagaag atgaacatcg
     8521 gagaaaaaat acgaacttac cgcagaaatt gtaagcttac gcaaaaagaa ttaggcgaaa
     8581 aaatcggtgt ttccgataaa acaatctcta gttgggaaaa ttctcgtaca atgccagacc
     8641 ttgaaatgct gtcactttta catcagactt taggtctgcc gattgatttt ccttctattg
     8701 aatcagctac cgaatcaata gaaccaacat tgccggatga acctcttgtt atcaagaaat
     8761 cttattcatc aaaacaaccc ttctcactca aaaagacact atctttcttt ctgctcgtct
     8821 tttgtttggt ctatcttttt cttatcaatt atcaatataa aaatgaaacg gttgatcgat
     8881 tcaatccttt tttgaaacca caaatcggct ataccacact ccctgtagga tacgtggaaa
     8941 attccatcga acattgggta tgtaatgata tctttgttca tggtacatgg ctgtcttttc
     9001 acgctggaga ggtagaaaaa ggtaagaatc atgctgtaat caaacacaaa ggaaaacacg
     9061 tcatgaacgt tcgcctgctc acttgggaag ccattccctc agattaccaa gaaatcctca
     9121 tccaagacta tgacgatgcc ttaaaaagaa gccctcagga gccagatagg cattaagtag
     9181 gagatgaacg tagagataga aaaaatcaat gcacatgatc ttatcaaaaa aaaacagggg
     9241 tacaaattaa ttgaaaaagc tttgagatga aagttcctaa ataaaaaagt tcagaatgat
     9301 aggtaaaaaa atgactaact attctagtat taggctattt gtattattct tctgttattt
     9361 ttatatcaaa aaatccagaa ataactaaat ataggtattt ctggcttata gtataatatt
     9421 tacgccacag cccccaatga ttctttttgg aatcatgatc aaggacggac atacacaaaa
     9481 atattttgcc cattcgatcc gaatagatta acgactaatc tagtaagtaa tatagattgg
     9541 tacgtagtca aaccagcaaa tggaaaagtt gtctattcca ccccaagggc tttaaagaca
     9601 gcatcttccg gcgtttgata aaaaatcaaa ttaaaggtac ccattaattc tgggggtaca
     9661 gttccaatat cagcagcgct tatcataggt acaagtactt ttttcgctcc ggcatctttt
     9721 gctacttgta aacagttagc taaattatct accttaatca tagaaccacc aattgtaata
     9781 tcccctaaaa taactaaact tggtaataca ggtttattta aggaaactga gcataaagct
     9841 attatagttg ataacgataa tgtttttgtc ataccaatgc cattcatatc ttgaacatga
     9901 acgacaaaat cttttgtcgt caaactaata gactgactaa cacttccata attagctctt
     9961 aaatatcggt atgccgaatc catcgcttct cttgctccag catctgaatt gatcccagta
    10021 cgttcaaact ttccatttcc cgaagtcatt tgcgtttcca atttataggt acctaattgc
    10081 ccagttttgc cataagatac cgtgtacaaa tgccctggct tccctaaccc ttctggaatc
    10141 aaagttcctc caccttgttc aggaacagaa acatactctt ctcgctcttc ttctaaatca
    10201 atgtatgaaa aattgacatc ataaaattcc attccaccaa ttttctttaa ttgttctttt
    10261 acacgacgac gcatttcaag agcaaatctt agtatttctt cgacatcact tttttcaaat
    10321 ctaccatcag gatacaacag tttcatcatc ccagatacaa tccgacgaac tgcaatcgta
    10381 tcccgctgat ttaattgaga accaagtttg aaatatttat caaaactatc gccaaaacta
    10441 acttttcgaa gctcacgcat gacttcagaa aaataatctg taatgaagcc atagtcattt
    10501 gtaaaaaaat ctggtcgata tttaggaatt tcccaacctg gtaaataaca atgcatccga
    10561 tccaaaaagg ctgaatccgt ccccataacc tccggaaatg gctcaaataa attcgaagtt
    10621 ttcaatatta catcaacgct ttgattaata tttcctacaa aagccattga tgctgaagca
    10681 ttcttttctt ctttgcctct agcaaaagat cctgaagcca tgtaatcttt catgatttga
    10741 acgccatcat tatccttaaa tttaatccca gcaacttcgt caaaagcaac acagtcccac
    10801 atacctacaa gtcccattgt acgactagcc atattataga aaaggtttgc tactgttgtt
    10861 tgtccacctg aaacaaggat tgagtttggt gaaatttctt tatatacatg cgatttacct
    10921 gtaccacgtg gtcctagttc acagagatta aaattatttt caattaatgg aataagtctt
    10981 gctaaatgaa gccattttac ccttttatta aattgtgtag gttccatacc aatggaccgt
    11041 agaagtaagt caatccattc atttgtagta aactccttgc gagccatctt gtaagcctca
    11101 atgtctaaac caggcatttg gattggatca accttttttg caataaaagg gctattccaa
    11161 cgatcattct catcatacca atattccatc gaaacaatac accagatccc cccacctaat
    11221 aatcgatcaa attttttcgg atactcttca ctaatttgaa cattttttaa tcccaggtta
    11281 gagaattctg cttcataaca atctttcttt tcatttaaat gtacagttac tttatcaata
    11341 actgtataac cacccaattc acgaattttt gcttttactt tttctgcttc atcaggacgc
    11401 acatagtttc gagcaagaat atttttaaca ttttccacac ctttttcaac caatgtttca
    11461 tccaatgacg aagcatacat accaagtaaa tattccaata cataaacagg tacattcgca
    11521 ccttctttaa ttttctttgt taaatctttt ctgacaatct ttccgggaaa gaattcagat
    11581 aactttaaaa tttcctgttg ttccactaga attcctccat gtgttcagtc attataatag
    11641 caattaaagt atatcatact taaccagtag gcttgataat acaaaagaaa aagtatccac
    11701 aaaaaattgt ggatacctcg tttttatata tcaaaatcaa atgattctgc aaaaggatta
    11761 tctataatga attttattcg ctcggtcaaa tcattttttt gattttttat cactaaataa
    11821 taagtatctt caactgtata tcgacgattt acaaattcaa aaacaaattt agtaaaccgc
    11881 tgatttgcat cttctgtttt tgaatccgca acatagattt cttcatttga gatacgttca
    11941 ccatattcat cttcaaaata aagccagaaa gatgcggggt cataaacatc actaattgca
    12001 tttttttgat agaattctaa cgtggttgat aatcctgtaa ttctgcggtt gctagtcatt
    12061 aattcaattg ctactggttc ctttgcattg ctacctttgg ctaccgtaat ttctagaaca
    12121 gggactagca tttcttgaat agatgaccct ccatgaacgt agctttgtcc cccgccagct
    12181 ttcttaaaaa tacttgaagt aatcgggaca caaatgtttc tagtgtcatc atttcctaaa
    12241 gaatctccca aagagtaatt tttcgtacca attatttcgt attcttcttc actaagaata
    12301 aaacgacgtt ctacacgatc tttttcattt ctagatggat tttcaatctt atctacttct
    12361 tcaacgtggc ttcttttata aataaatcca tgatcagccg taactataaa acgatagata
    12421 ctgccatcat tatgcaagcg attaataagt cgggaaattt cgcttatcgc taaatcacag
    12481 gcctcaaaaa ctcgattttc attcgagtga tcacctgttc tatccacttg atcgtgataa
    12541 atataaatga ctgatttgcc attaaatact tctcgtacct cagccttatt catcttaacc
    12601 acatcatcat aatttaaagc tacagcattt gcatctcgtt gctggagaat cgcatttcga
    12661 ttggataaac cattcgtttt tttcccatca atcagtactt ctgttccttc attgtaagtt
    12721 agttgattgt ttggtaataa ggcggcttta ccgaattcag taactgaagg taatacagaa
    12781 agaaagctag ccatgtttgt tgaatacttc ttttctctaa ctaacttacg ttctaaattc
    12841 atccctaact catatcgaaa agcatctgaa ataataacta cagttttaac agagcgtttc
    12901 attacagctt gattataaaa ttttcgaatg gatggacgat tcttaaattc aaaagtttga
    12961 ttccaaattt gtcctgattg atcaagaaac ttcgaataat ttgcttcaac taatcgatac
    13021 aattggccat atttttgctt ttcttctata tgatcactat tccaaataaa tttccgataa
    13081 tgcgtatcaa cccaatacat ttccttctca tattgagtta gcaaattatc catgttcatc
    13141 ggcaagcaca atctgttttt atccacaaga taataagcat gtttcaataa ttgatactca
    13201 taaatataat ccgatgcgaa atgcattttt tcgcgctgct ttaaactatc aaaaattgtt
    13261 tgtcctgcaa ttttcgttgt agtgtcagaa gcctttaatc gttctgcata aaacattaat
    13321 atttttgcat gaatctcaga aaatacgtct gcttcaatta gatcatcaat ttctatactg
    13381 tctaataatc catcaccatc aatagcctga tatacttttt tagatagctg ttcaaagctt
    13441 tccatgtaac gtgtatcatt cataaactga tccatgaaag taataatgtt tgctttcaaa
    13501 tgtagtattt caaatccttt gaacttcttc ggcatctctt gatcaatttg ataataaaaa
    13561 tagttcaaat aaagacacat cgtcagcttt tccaatgttg gctggctatc cgtaaagcca
    13621 aatttcattt gaataaattc ccaaaattta gctgttaact gatacttatc aagttccctt
    13681 aaaggattct ccctactttc tgtaaagctt tttagaacta cacgcagtaa atcatttaat
    13741 cgaatacttt tcgatttcaa caaaacagcc attatcatta attcaatcgt ttctgattta
    13801 ttaattgtca tatgcgtact aaattcacca aaacttctca tgcgatcctt tgcattaaag
    13861 aaattacgat actgtttaac tgtctgatga aatctaagtg gaatagccaa ttcattcatg
    13921 ataatcgcta agcggtctgc actaaattcc tctgaataat tcaatacact caacaaatga
    13981 ttatcttcat ctttatcatc ccaacgagga aatggcgcat agattaaata gttagtttcg
    14041 ggatcttcat attccaataa acgcttagtt ttaaattgtg cgtccttttc taatcgatag
    14101 atttttgcat tttgaatgac caatgagtca atttcttcaa gaaaatcctg atttgaatca
    14161 aaccaaaaaa tgattttcct acatccataa ttaggaaaac gttgatttaa tttttcttca
    14221 atttgttgcg tatttatatc tgtcatcaat ctcacctaat cgttctcttt ctatacccct
    14281 tatattgaca taatttggat aatttcgcac gcaatttaag aataaaaaag aaagttgtta
    14341 gaaaacaact ttcttagata actatttttt tggttctttg accccttttg caaaaatttg
    14401 gaatttctcg ccggttttag gatcacgctg caacttatca taattgacaa ttacaccatc
    14461 atctaagtct aattcaattc gttttaatgc taagtgaccc aacttctcgt catactcacg
    14521 aacttctttt aattgcttct gaatctttac aatttctttt gtcattgcat ttctttcttt
    14581 tgggttatca cttgttgaaa tttgttgctg acgcaattcg attcgattgt catacgcttt
    14641 ttgtagttcg tgtaggtatt cagtacgtac ttttcctaat tgatctggtg tatagcgatg
    14701 caagtacatt aacgctttaa agccattttg ttttcctgag tccaattgcc aataaattgg
    14761 tcgattggag tatgttttta aatggtcttt gtaaaaatct tgtacgaagt aacgacgaat
    14821 aatttctcga cttgtccctt tgccacctaa agtgtcagcg ataaactgga gattttcttc
    14881 aagggtttct ttaccaaaag taatctcaac gaaatcaatg aaacgattga caatgtcaat
    14941 ttggctatcc ttgaaatact catcatcggt gatgagtaaa acattatcag tatcaggttt
    15001 aaatttttga tagcgggaag gatcccattc gccgccagcg aagatgagac catcttcgtc
    15061 tagggagtaa cgaccgaaga tacaacctat tgaataagaa ataaaatcct taatttccct
    15121 cgccttatca ggtaaccttg cagagatata ttcatcttga acctcttttg ttaattcttt
    15181 ttcaagagaa taatgattaa tgaatatgtc gttcagttcc tcttcattcg attttagagt
    15241 attaaattga ttaaccaact gcctacttag acagttaaat gcctctgaga gatctttttt
    15301 aaacatataa cttaacaaaa tgtttcttct aaactcgtat gacgtttcaa gagcattata
    15361 gtcttttcta gctatatcga tattttcatc cactttttct cttatttttt ttaattttct
    15421 ctcagatgta actttaagaa aaggtagttt tcccattggt ccttcatggt aatccaaggt
    15481 gggagaaata aaagttaaaa agtgattaac taatttagag tttacatagc caaatatttc
    15541 ttcaaagtca gttatatcct ttgagaacag aacagatcct ttagtttcaa aaattgcctg
    15601 attctgcaat ctaaaagata cttgtccaga tgaaagtgtc gaccaagtaa ttcccttttt
    15661 aaaatagtaa ttaagatttt gtggtctaga ttttaacttc ccattttcat taacataatt
    15721 ttttatttca tctccatcat tctcccagtt aaccacgtat tcattgtttc cataccattt
    15781 tctaaaacga ccacctttag ttgtaggaaa ccattttttt ctagactttt tagcgtcctc
    15841 taatgtttta gcatcaaact ttattttgtt aaattctact tcaaaccaat accgcaaaaa
    15901 tttattgtta tttccggttg ccaacccttg ttttgcatct gcaacatcgt tagttaattt
    15961 tccttgagca aaatcagtga ttacgttatc gcttgcccag taagcaatcg gcattcctgg
    16021 gatttttttg aagttgtctt gattagtact ataaaaataa tcgcattcac catgctgatg
    16081 aattgcttct aacgttttaa ttttttgaac ttccattcca cctttaaaat ctgataattt
    16141 tatatagctt ccatcttgtt catttgaatt ttttatcgta aacgtacaaa ttggaacggt
    16201 tgcttcttca aaagctgaat actccatttg aatcaaacta gaaatgtttc tttcattaat
    16261 taaaaatgag cgtaactttt catagctaga aatgaacatc caaacaaatg gcgtcataaa
    16321 ggaagcatat ccattatcaa tcagcatttg gctattcaat ttaataaaca cagaaaatag
    16381 atcttttttg acatcagaat agttatcatt tacatatttt tttaatttct tatccatttt
    16441 attaagataa ggcggattag tgactaccgc tacatattta tcaactagca tttcagccac
    16501 gtcaagaatg tgcaagtatt tttcttgtat ttccttcatc ccataaagaa tatccatatt
    16561 cgtaaattcg ttgaattttg atatatactc tcttactttt cctaagtatt ctttagttat
    16621 tgcctgatta tttttatcga ctaacttaat gattgatcca agttctttcc cattttcaaa
    16681 ttgatcaaaa attaactctt tgtattcatt ccagcgttca ctatacttat cattgttcaa
    16741 ttcactaata cgctcttgat actcgtctgt cactttagga gaatcaataa actctcttaa
    16801 attcggcgat agactttttt tcaaaaaaag acgatcgtat tgacgccctt tcatcataat
    16861 tgcaaaataa gacaattgat acgctctttt atcgatttca agaccatata aattgtattc
    16921 aacgattgca cgtgcagcat cacgctcaga atatcctaac gtaagataaa tttccatcaa
    16981 tacatcgaag gcgtaaacta aaatatgccc agaccccatt gcgttatcga taatttttag
    17041 ttcttctggt tttaaattac ttacagatgt tgcttgttca aaagcatatt tatctggaat
    17101 taagtatttc aacttatttc ttaattcact attgggataa tgatctaacc aatactttcc
    17161 taaactattg tcaaccatat aacgaacgac ccaatctgtg gtaaatagtt gagttgctgc
    17221 cggaatatct tgttttttga caatcccttt ataaatattc accacttgat tatgtggctc
    17281 actattatag tactgataca accacccaat aatctctacc tgtccaccag cttgaacata
    17341 gaaatcatcc tctggaatac ttaaaagatc agcgattaca ccatcttttt taatataaga
    17401 agctgtaaac aaaagttctg tataatcttc tacttcttca aatagctcag gtaagtaatc
    17461 attcaattga ttacagattt ttataaaaat caattgatac agcttgtcca ttgcttctgc
    17521 tgaattatct gttttccaag ttctgacttg ttgctgttca ttactagata attcttcaaa
    17581 gatatcggca tcataaatat ctgtaataat atctggctca attttcccac ttatttcact
    17641 agataataca cgatacgtgt caggtaaata atcatttacc tccataaacc gaatggcaat
    17701 caatcggtta aaccacgtat aagcaacctc ttcgattaac tcttgaaaag cttctgaata
    17761 agaagtgaca gaagcacgtt gttttagttc tgcaatcaat ttgtttcttt gcgctatttc
    17821 ttttccttga attcttattc ctgatttttc gatttcttgt aaattgctat caattttctt
    17881 cacatcttca atttttgatt catcaattcc taaacgtttt gctttagtca ttacttcatc
    17941 aattaatttt ctacgggcat tgaccgcgaa attctttatc gctttcttat ccatttttct
    18001 ttcccttcta tatgtaacct ttgaaaagac aggcaccttt ttatgcctgt cttttcacta
    18061 gaattgaatc gtgatttctg tattttcttg aagttgttcc ttcagttttt gattaatttc
    18121 agctgttaac tcatcaatat ctgctgctga cttaatagtt ttaacatgaa cgttaagtgt
    18181 tctcattggt actgttttct gttgaatagt aggttttact atcgctattt cttcagcttt
    18241 tgctgcagag tctatttcat ctttttcagt ttcacgaatc aagtttgctg cttcaatttg
    18301 tttacgtgct tgttcttctt gacgtctgcg gttttcttca ttatcgaaac gttgattaaa
    18361 gatcaaatac tgttctgcta cgtttaatga taagaaaaca agatcatcta tagtattcgc
    18421 ttgttcaatt tttgctttca gttcttgaaa ttcttggtca actattggta caaattgatc
    18481 cttaaaatct tttccttcta ataatttaaa tgttgcttgt ttttcttccg ttaatttatt
    18541 taatatttcc tgactttcca actctaacag ttgattatat tgttcaataa attcttgaat
    18601 caactcattt agtttcatca tatctgaata aggatcagcc tttttcaaaa tggttttcat
    18661 ctcatgaatc aattgatcaa tttcttggct agaagtttga cgccgacttt tttcgattaa
    18721 tctaatttta tcttgtgcat tctcccagat ttttttctga gtactatttt gcttgtggaa
    18781 atttttaatt ttatcatatg tttcagccca gtcgaataat tcatcgcgat attttttgat
    18841 tgtataaaaa aagtcttcaa catctgacgt ttgaacaatt acttcaagat atttttttat
    18901 ttgctcatat tcataagcac tagggtaggt ataagtgttt tgtaaatcaa aataagagcg
    18961 taaattgtct aattgacctt ttaaatattt cttgaaattt tccattgtat gttcattgtt
    19021 attttcatca acaatattac gactttgaaa cagttctcta ccgatttcgt caaccaattt
    19081 ttttgctttt ggcgaaatca ccgcgcttgg ttcaattttt atcttttcac tttctcgtcg
    19141 tttttgaata atcattacaa tactatttgg atcatccatc cgtgaaattt gtacattgtt
    19201 ataaagtaaa tcaattttac cagacatgaa aagtttagcg atgcaccatt ccacatcaag
    19261 ttctgtgaat ccatacggtt gttttgtttc aaaacgatca cgaattgttt tcatcgtaat
    19321 cgttaggtga tttctctttt gatcattgat aaaattgaaa atttcctgaa ctgcttgctc
    19381 atttgatgga tcttcaataa tttcattttt gctttctttc actaaatata agatatcttc
    19441 tttttcttta ggcgcatcaa tttggtttaa tttatggtat acttcttcag ccattttctg
    19501 aagtgctgat tggaattttg ctttaaagtc ggagcctgtc agttgaattt ctgcaccgtt
    19561 atagaaaaat tttgcagatt tcaacagttc atttaattga tcgttgatac ttgcacttag
    19621 ttcctgtaat tcaccagatt tttccgaacg aatcgcgtca aagttcttta ctacactcga
    19681 ataagtcgtt gttaaataaa gattcattct agcatacatt gctatatcat ctttaaattc
    19741 tttatctgat ggcaattcta cgaataataa gttacgggaa ctcttaagcg caagttctgc
    19801 ctcttgacct gctaaatcag agtatggtga aataaaatta actgtcattt cagcatttcc
    19861 agcttgcttg tatggacgtt gatctaacac ttgtgcataa gtaaacgtat accggttttt
    19921 aaatttattt ccacctgaca tgcctaattt ttcataggca aaactatttc ggtctagaac
    19981 gccgtcaaaa attcgtttag atagttctac gatcaaatca ctatctgtaa tattttgatt
    20041 tttaatctca cgagtaattt cctgttcttc atcagtttgg aaaatataac tatctaagtt
    20101 cttccgcaca aagttttcct taattaaaag gtccaatgct tcttctactc gttttttagt
    20161 ttccaggcgg tcttcgttga tatttcttat catcaagctc gtaatatttt caacatttgg
    20221 tttgatggct tgatcaacat atttaatcat gaataaaatt cgtaagacat ttacgttaaa
    20281 gttatctata tcagttggtc tttgaatatg agaattattt gtagcttgtg taatcactcg
    20341 gctaattgct gtatcaatcc aacgttctaa cgagtaataa aactgatcta aagaaaccaa
    20401 actggttgta tcattttcct tatttcgttc agcggcttct ttaaacattg ctagtaatga
    20461 acgttcacca gacgataagt ttgatccttg atagctgtga ttacgaatct cggttagaat
    20521 ttgccccaat aaattgaatt gatagggaat aaatggataa acttctgcgt aattttcagc
    20581 atcttggaag agctttaatt caggactatc aacaaagagt aatttatttt tcaattctgt
    20641 ttgaacagtt tcaaattgta aggctaaaga atcattggca aactcttttt tcttcaaaat
    20701 acgttcttta attacttcat cggcatttgc tgaagataaa ctcacagttg tggcaaaacg
    20761 atccttgatc ttagaaaaat cattatcaga attgttatca aagtttgtta cgtgatcaat
    20821 cgcttcctga cttgtcacta atacccaagc cttaccttca caaattcgac ccaaatcttc
    20881 cacaacggtt tgtaactgca aagtcaactc acgattaccg ccgatatatt gtccgacctc
    20941 atcgactaga aaggcaatat gatggtctgc ttctttggaa tcaagatagc ttttaactag
    21001 atttgcaaag tcatcaatgc ttattaaata atttcctgat gctttttcta aaaaattatc
    21061 aatagcggct tcactcataa aatcgatttt aagtgccgct tctttgatat catcttggat
    21121 ccaatcaaac tcatggcgct cttcttgcca ttttgcccca ttaatctctt caaaagcagc
    21181 tttgaatgca tcaaactttt cttctttaat taaccgacgt tcaaaatctg ctagatgtgg
    21241 aatcgtgctt aatccttgca tttcgttaaa tacctttaaa aaaacattca cgattccgtt
    21301 tttgtctttt ttaccacctg catcactttt tgaatcaata ttaaacagaa taacatctgt
    21361 atttatttgt gagcaccgtt ccatcgttgc caaagtcagt ggatctttga ttttcccatc
    21421 ttctttgaag taatcaatgg ctttcttgtc atttatttct cgatttgcga gcaagtaaga
    21481 aataattttt aagaaatgag atttacctga accaaagaac ccctgaatcc aaacacccat
    21541 tttatctgtt ggtgtattga tactccgttg gtaggcatca aaaattgttt taaagtgttt
    21601 ttgtagttct ttcgtaacca cgtattcttc taattcttgt tgaacatttt catcctttgc
    21661 ttgaccgacc ttaataactc cttgaatatt tcggtcaatt ggttttgcaa aaatatcttt
    21721 aattagcatt taatctccta ccttccatcc caactaaatt ctaaatgctc gataataatt
    21781 atcatcttta ttggtattaa gaattgtcaa acttaattca tcatattccc ctggatacat
    21841 catcacaact ggtacgcgat caaatacctg atgcatttta tttaaaatag agtgcgctct
    21901 aattaatgga tataattcgc caattcctgt caggaacaca actgattttt ctggtgtatg
    21961 ggcatccaca tattcaaaaa atacattttc ttcctcaggt aaatccattt tcaataaacg
    22021 accaatgctt tccactaatt tttgtaaacc acgtcgttct tccatcttaa tcgctttttc
    22081 agtgaaaccg cgtttttcta gatactctaa cataatcaca tagagattat aaactttcac
    22141 ttcataatta tcaccaacag atgttccaga tatatcatta atataatctc ttacaattaa
    22201 ctcgtctttc ggatcgtagt caaagatata atagcctact tcattaccta aaccacgatt
    22261 caataaaaaa tcttcttttt gaattacttc attcaacttt tccaaatgct cttgaatcga
    22321 taatgacatt ataaaattcc tcccagtgct agtacaatat ctttacgatt cttgtcaact
    22381 aaccattgaa tcaatcgttt atctaataat atcggagtca ttcgtccata ttctttttcc
    22441 cctctgacta atcctgtttc aattagattc gtttgataag cggcaataag ccgtttaatc
    22501 gtataatctt tccattttga aatatcttct gaacttctcc gcttctctgt aaaaaaagaa
    22561 cggtaatcaa ctggtgttaa ttgcaaattt cctttacgta gattttcagc atatacctca
    22621 gtcataaatt cattaaaaag atcatcaatc ataaggatgg aaatcaaatt cactaacttt
    22681 tgattatcta tatttaactg attgaaaagt tgcaatccag cttcatccag ttgactaact
    22741 ctccttttca cgttctgata gatttctttt tgacggttac tgctcactgc aaaaaaaata
    22801 ttttcatgtt catttttctc tttaatttct atatctgtat atccttctag tcgtaattga
    22861 atatataact tgaactctga aaaccaaaag cgtttagaaa ctagaccagc agaatatttt
    22921 ttattcaata gattgcctcc taatcatcta taattcaata agtaaacaag tgttttttgc
    22981 tcatcgttag cattcatttt ttagtatcta ctatacaata catatttatt atag
//
LOCUS       DACCVZ010000042        22421 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.042, whole genome shotgun sequence.
ACCESSION   DACCVZ010000042 DACCVZ010000000
VERSION     DACCVZ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.042"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            6..305
                     /locus_tag="IVW63_001643"
     CDS             6..305
                     /locus_tag="IVW63_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7859921.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="IVW63_001644"
     CDS             378..1739
                     /locus_tag="IVW63_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAP7859922.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="IVW63_001645"
     CDS             1761..2021
                     /locus_tag="IVW63_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859923.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="IVW63_001646"
     CDS             2035..2787
                     /locus_tag="IVW63_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAP7859924.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="IVW63_001647"
     CDS             complement(2881..3486)
                     /locus_tag="IVW63_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP7859925.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="IVW63_001648"
     CDS             complement(3539..4513)
                     /locus_tag="IVW63_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HAP7859926.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5670)
                     /locus_tag="IVW63_001649"
     CDS             complement(4891..5670)
                     /locus_tag="IVW63_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7859927.1"
                     /translation="MLLRVVGSIIFRYTLEEVNNVPKYEEIANILRERIRSKEYPLDS
                     FLPNQVDLVKEFGASRMTIKKAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEY
                     EGLSLQMKRRHRSLKSQIIHFDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVL
                     EHTFMPVHLVPGLKKEHLLASIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAE
                     NDPVLEVQQVVYLKDGQPIEYSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="IVW63_001650"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="IVW63_001650"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAP7859928.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="IVW63_001651"
     CDS             7161..8558
                     /locus_tag="IVW63_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP7859929.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="IVW63_001652"
     CDS             8639..9079
                     /locus_tag="IVW63_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP7859930.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="IVW63_001653"
     CDS             9227..9553
                     /locus_tag="IVW63_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP7859931.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="IVW63_001654"
     CDS             9554..10303
                     /locus_tag="IVW63_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859932.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="IVW63_001655"
     CDS             complement(10383..10838)
                     /locus_tag="IVW63_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP7859933.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="IVW63_001656"
     CDS             complement(11265..11540)
                     /locus_tag="IVW63_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859934.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="IVW63_001657"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="IVW63_001657"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAP7859935.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKGLQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="IVW63_001658"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="IVW63_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAP7859936.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="IVW63_001659"
     CDS             14770..17436
                     /locus_tag="IVW63_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP7859937.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="IVW63_001660"
     CDS             17800..18552
                     /locus_tag="IVW63_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP7859938.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="IVW63_001661"
     CDS             complement(18574..19728)
                     /locus_tag="IVW63_001661"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HAP7859939.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="IVW63_001662"
     CDS             19913..22354
                     /locus_tag="IVW63_001662"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HAP7859940.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         7197 a         3933 c         4674 g         6617 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaaggact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagctg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt t
//
LOCUS       DACCVZ010000043        22330 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.043, whole genome shotgun sequence.
ACCESSION   DACCVZ010000043 DACCVZ010000000
VERSION     DACCVZ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.043"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            26..805
                     /locus_tag="IVW63_001663"
     CDS             26..805
                     /locus_tag="IVW63_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859941.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSYVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            851..1795
                     /locus_tag="IVW63_001664"
     CDS             851..1795
                     /locus_tag="IVW63_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7859942.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVAIVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            1811..2590
                     /locus_tag="IVW63_001665"
     CDS             1811..2590
                     /locus_tag="IVW63_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HAP7859943.1"
                     /translation="MEETINLEEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            2602..3300
                     /locus_tag="IVW63_001666"
     CDS             2602..3300
                     /locus_tag="IVW63_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HAP7859944.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3328..4092
                     /locus_tag="IVW63_001667"
     CDS             3328..4092
                     /locus_tag="IVW63_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HAP7859945.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQITAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            4137..4826
                     /locus_tag="IVW63_001668"
     CDS             4137..4826
                     /locus_tag="IVW63_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAP7859946.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYISHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            6053..6733
                     /locus_tag="IVW63_001669"
     CDS             6053..6733
                     /locus_tag="IVW63_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAP7859947.1"
                     /translation="MIGIEEKKGVQKDVTIDREENLRGHRFYWIGRRAQDIFFSALAL
                     IALSPVMLITALAIVIDDPGGSPIFVQDRVGRNGKLFKFYKFRSMCVDAEAKLEALLA
                     QNEMDGPVFKIKDDPRITRVGKFIRKTSIDELPQLWNILKGDMSIIGPRPALPREVEQ
                     YGDYERQRLFVQPGLSCYWQIAPHRNELSFEEWVELDVKYINERSFITDWKIIFLTLQ
                     AVLFGYGE"
     gene            6762..8075
                     /locus_tag="IVW63_001670"
     CDS             6762..8075
                     /locus_tag="IVW63_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAP7859948.1"
                     /translation="MNIILLSGGSGRRLWPLSNDIRSKQFIKLFKDENGEYESMIQRV
                     YRQITTVDPDAKVTIATSKSQASAIHNQLGDKASICVEPCRRDTFPAILLAAAYLHDE
                     LGVGDDESVAVCPVDPYVDNSYYEGVEALEKLVQQNTANLTLMGIAPTYPSEKYGYII
                     PESSNEVSTVKEFKEKPDKATAEKYLAQNAVWNAGVFAFKLGYLLEKAHAMVDFEDYR
                     DLYSKYETLTKISFDYAVVEKETSIQVMRYNGDWKDVGTWNMMAEVMADNIKGKAVMD
                     DTCVNTQIVNELNIPILAMGCKDMVIAASGDGILISDKERSGYMKPYVEKISTEVMFA
                     EKSWGTYTVMDVQEGSMTVKVSMQAGQKLSYHYHNSRDEVWTVVAGQGKAIVDGMKQI
                     LRAGDVVTIAAGCKHTIEAVTNLDIIEVQIGETISVADKYKSSLN"
     gene            8881..9648
                     /locus_tag="IVW63_001671"
     CDS             8881..9648
                     /locus_tag="IVW63_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HAP7859949.1"
                     /translation="MGIEGGYLMSRMRFMNTEIDNLTMGEVLVEVEKMIQDRRCGYVV
                     TPNVDHIVQLETGKELQDVYKNASLILTDGKPLIWISKFYKTPIKEKISGSDIFSLLC
                     KMAAEKGYTMYFLGAAEGVAAKAADNLMKRFPGLNVVGTYSPPYGFEKDEDEMFKIDS
                     QIKRANPDMLIVGLGCPKQEKFMFYNCDRLGVPVSFGLGASLDFEAGNVKRAPKWMSD
                     YGFEWLFRITQDPKRMAKRYLVDDLKIFKLALKYRKK"
     gene            9675..10676
                     /locus_tag="IVW63_001672"
     CDS             9675..10676
                     /locus_tag="IVW63_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HAP7859950.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFRENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSTELSYSRTERVTNIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALKGKYADKKKLVDKAIYLERVLCNEAGGWQDQIAAAYGGFNRI
                     NFNSDGYEVLPIIITPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAVLTDKNRDLDDFGRLLDLTWRLKKATGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQNAVRSAMSNLMYIPFEFENGGTQVIHYTPEMYIPK"
     gene            10699..11985
                     /locus_tag="IVW63_001673"
     CDS             10699..11985
                     /locus_tag="IVW63_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HAP7859951.1"
                     /translation="MKVVIMAGGKGTRISSVASDIPKPMIKIENKPVLEHEIECLRDQ
                     GFTDIILTVSHLGDIIMNYFGDGSGISPVTGQPFDVKIEYFLEKEPLGNAGALFRLKD
                     NLTEDFLLLNADAMFDVDFNRFVAYHREKGGLVTLFTHPNSHPYDSGLIIADKDGSVD
                     RWLVKEDSRPTYYRNRVNAGLHVISPAVLDVEINTPKIDLDRQLLKPLAGTGKMFCYD
                     SPEYVKDMGTPDRYYAVCEDFKAGRVKGKNLQNKQKAVFLDRDGTINQYVGFLRHIDE
                     FELIKGTEDAVKKINAAGYLAIVITNQPVIARGEVSFEELEEIHNKMETLLGYKGAYL
                     DAVYYCPHHPHKGYEEERPELKFDCECRKPKPGMLIQAATDFNIDLSQSWMIGDGEND
                     IKAGQAAGCKTALVGESEYGQDMTIATLSEFADKIC"
     gene            12019..12672
                     /locus_tag="IVW63_001674"
     CDS             12019..12672
                     /locus_tag="IVW63_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP7859952.1"
                     /translation="MIDNRLQKHIDLLIKRYPTLEVIKQDIVDGYLIMEECYLNDGKL
                     LIAGNGGSAADSEHIAGELMKSFKTPRPVSREFADKLIAVDPVKGSELAKNLEYGLMA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRPGDVFLGISTSGNSKNVINATVVARA
                     LGMKVIGLTGAKGGELARVADVCVKAPETETYMIQEYHLPIYHCWCLMLEDKFFGNR"
     gene            12705..13910
                     /locus_tag="IVW63_001675"
     CDS             12705..13910
                     /locus_tag="IVW63_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP7859953.1"
                     /translation="MNVLFITTQFPYPLDNGGKIGAYNGISVLSRDYDVTVLSFTEEP
                     QYVEEGVSFFREKFNSVKFENPVIHDVHIRNNPMKLVEALAIGYCLRQPYIVSKFYDS
                     KMLQLIDEKFSNNAYWDIIFIDYLNMQSYGQYIREKYKTQFGKYILKDHNIEYDLVLQ
                     EAESSRGLKKKLLQLEYKRTRKYEEAAVNRADYCFSVCDANTEVLKKINDNSYTMLPT
                     YEMLTGVKKNIEKNTILYLGNLSWKSNMQGLVWFLESIYPNIQQRIPDVKITIVGSGP
                     VGTDFSKYSGVDYRGYVKDISHIYDDQAVLIVPLLEGSGIRIKILEAFNNEIAVVSTL
                     VGCDTIGAKDGSELFIADNEKDFATAVVRLLEDMNLNEKVRKNAKLFLKEKYSLTARQ
                     DEFSAIINS"
     gene            14040..15365
                     /locus_tag="IVW63_001676"
     CDS             14040..15365
                     /locus_tag="IVW63_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859954.1"
                     /translation="MIVAAMSYHLTGNSNVASLIAVVGVVYAIVKACNNEYLAIWVMF
                     VLGSDIWGIVPYINIGSGVLHWSDFNVIVAIFLCLRFIKVKARSRYGIVYSVMLIFIL
                     IACVQSHSIYGQDVHTTLLTARELLVVISFWPIVKIVYSERITKNEFIDLVCKFTRWT
                     MCIYWFEWILVNMGFNITFLQTGARWGTRIYIDPIFIILYFFINLYAVIYKREGYNST
                     NKSIWNCIFSLLTFVIISQGRSGILYVVITSVIMLLISLKPSKIIRFGILGIALIACL
                     VSVTQIREVVISSFVESQSSDTGNIAYRIAEQDYFENKLEGHELFGVGIPNNHDARAV
                     EYSGKTIDFESKKYNPYYLEDLGAFEIRYRFGIIAYALYIVALAISIIDAGFRRDKSV
                     AAFAGMAFMVFMALNFNLLAYITARPFGFMISLILIEISAFNDEFIYIE"
     gene            15382..16512
                     /locus_tag="IVW63_001677"
     CDS             15382..16512
                     /locus_tag="IVW63_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859955.1"
                     /translation="MNLDRLKKIANMISPIIKVINAPLAYFSGKSDYMEKGILWPTVT
                     TYSNNSRKVIQYTTLPKNVDNMAQMQWAGESFEDICIVLQGPVLEDGDFTLNTVKMYN
                     KYYPKVKLVVSTWIGLSEETECKLREAGADVVLCKKPEKTGAYNINLQLTSAYEGVKM
                     AQKLGCSYALKTRTDQRLYANDVLKYFQTLLNIFPSSDCKVVNQRLIFTTYGKSFRYL
                     PFNLCDFLVYGETSELLKLYGIQRDNRASDFGKIIYTEEKEFNKKIFTLLEGKQGVSP
                     YDVFPDFDALYKKYMFAEYYIVYNYFLENIASNESYGDLMDAYYSYLKKYAVVADSEK
                     LLLYWPKYVQYNVKFENELDFYAKLDSKKWMDIYANYTPFSQ"
     gene            16538..17623
                     /locus_tag="IVW63_001678"
     CDS             16538..17623
                     /locus_tag="IVW63_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="HAP7859956.1"
                     /translation="MKIGIVTIVNGASFGNRLQNYATQKVLENNGYTVETINNCFDKE
                     STLSIVIKNAIYTLFKFIPHFKKSKSIWKRMYTFYQWDKQYIDYSHRKIDASKKNSFV
                     SIKNDYDYFLVGSDQIWNPKYAANKGFELLSFVPNEKRVSLSTSLGVPSIPSDLEKLY
                     VTEWNKFKSISVRENQAAKIIEDLTGTTAAVHIDPTLMLERSEWEAFQKKPDNIDENY
                     ILSFFLTNPPKDTVDVLDKVAKDLKIGVLTLDASWEYFQDITPNHFVYLISHARMIYT
                     DSFHCTVFSLLFGKPVVVFDRFDSEKMNSRLSTLLNKVNKAHFWVGKKADEAMIRAIA
                     SEPEYDIDKLMVSERECVKAYLKEYLQ"
     gene            17646..18461
                     /locus_tag="IVW63_001679"
     CDS             17646..18461
                     /locus_tag="IVW63_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859957.1"
                     /translation="MEHLSDCFGKMKIVTTSCAREYFKDDLDKSEYSCFVDSRAAMFF
                     AMGQALAKRRNVVVMLADELTSCYTALTECAFQQVDLIVFAFQTVRHEIDLASLKNCG
                     CNLINCSAQDDIDRVVSNTKGLNQTTVIKINMNCESDKDHICEYIDLPDIPVFFHGSL
                     YSPASKKKYEQYGQVSKYLGYLVGGKDAILIISHNEFLNDISVWINYYSFGEIQPKII
                     IFDSPNDYQYKWLCDLECSVAHSTNRFLSEDLALLQNNGISIVLRGDNYDIVS"
     gene            18445..20163
                     /locus_tag="IVW63_001680"
     CDS             18445..20163
                     /locus_tag="IVW63_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylase"
                     /protein_id="HAP7859958.1"
                     /translation="MISSVKNVQILVSLLKQHNIKDIVISPGSRDFQLVHSVETDSFF
                     RTYTVVDERSAAFFANGLSMAIDKPVCVCCTSSTASSNYMAAAKDAFANGIQLVLLTA
                     DRDYRRLYQMEDQMIDQVDMYGAYVRSNVDIPIVKDSDDEWYATRKINEAILELNHGV
                     KGPVQINYQLMDLSAPFVETMPEYRKITRYQEDDLLSSVEIFKQKLLSKKRIMVLCGQ
                     QEENNLSALLEEFFIKYNTIIIKDNYSNIHGEHFIKTVLVTERMSVNAFIDYCPDLVI
                     TIGKHVWSFVKYTLRDKKLKFEHWRISEDGKIVDPFNKLTSVFQCSAEFFMETVTAGV
                     NSNNNLEYYNLWKTRLSKVCYPELVYSNFYAISELVKKIPDSALVHSSILNAARLYDF
                     VSDDKALLSFANLGADGIDGCLPTFLGQAEADKTRPAYLISGDLSFFYAMNSLCGDIP
                     DNAHIFLINNHSGSEFHTNFGKFYNGSLSVDKHIAAGHISNAKDWALENNIKYITADS
                     KESLKSGLDVFINTFDSPVLFEVFTDPDTDTSVLESFYSINKVITPKMYFRKALDIIK
                     KHLHIK"
     gene            20189..21025
                     /locus_tag="IVW63_001681"
     CDS             20189..21025
                     /locus_tag="IVW63_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7859959.1"
                     /translation="MAIKSYIKRLLLYIRHGDPKINLDVSYLSEGAMLAGKTVIITGG
                     AKGLGFAIAKSFIAQGASVIITGRDMDSLNNAKCQLGDMCSIRAFDITDAKMYRTFFE
                     DAYETFGRIDILLNNAGISLHEDGFMSVTEKTWDKQMDTNLKGVYFFTQEFIKFVKEK
                     NQMQANIIMMSSERGLCGDSIPYGLSKAAINSLVVGLSKKYISEGIRVNGIAPGVTAT
                     AMTGISEKGNLYNPATIGYRYFLPEEVAQVALFLASSLSNCISGEIIACDQGQYLSRN
                     WG"
     gene            21030..>22330
                     /locus_tag="IVW63_001682"
     CDS             21030..>22330
                     /locus_tag="IVW63_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAP7859960.1"
                     /translation="MGILLKKYNSLSEPAKASIWFTLCNVLQKGILFLTTPIFTRMLS
                     TAEYGKYTIFISWYSIIAIFTTLNLSAGVYNKGLIKYENKYALTSSFLGLSSFISLCA
                     LMLYLPFRTVINGLLDLSTEFVILILIESIFEPAFLLWSVKERFDYKYQKLVLITVLM
                     AVLNPGLGIILILSFGEYAIWRVRAYVVVNVVVGMFIGIGILAKGKKLFDKEYWTYAL
                     RFNLPLIPHYLSMTLLNQVDRLMINSMVGASEAAIYSIAYTISSMMNIITTAINGSFI
                     PFTYKAIKDGVYEKIKSVANQLLVLIFVLCSFTMLFGPELIWVVGGEKYMDAVWIIPP
                     VAASVFFMFLYPLFGNIEFYYEKTNYVMFASCVGSIAKIISNYVSIPRFGYISAGYTT
                     LICYMLFSFAHYMFYKKILRENGIKEDMYNIKNIIFLSVLM"
BASE COUNT         7420 a         3266 c         4852 g         6792 t
ORIGIN      
        1 atcatcaata cttaggagtg aatctatgga aaagccattc gtcaagtcat tgactgctgt
       61 ggcggtaggt gcaggtgcta ttgcgatctg tttgtttggt taccatatca ataatcagcg
      121 gcaacatcag caacggatca attatgcaga atctgccatc accaatcaaa aagacacctt
      181 gacttcttta tcaaaagaag tagacaagct gtatagtaca aaagaaaaaa tttttctaaa
      241 ccctgaaata acagaagaaa caatcacaag tttgtcaaat aagctatcct atgtcaaact
      301 ttcagcagat gattacgaca tcaaagaatc agaattgcct aaagaagctg ttgcaatcca
      361 agatgagaag aaagcaatcg tgacacagtt agatagtgca gaatcaaaac tgaagatcca
      421 gacagctgtc aacgatttgt ttactaaaaa tgtatcaaac tggcagcaag ctgtagacga
      481 tgtcatcatc aaagaaaagg tgacaagtgc agatgtcgct cgtgtacgtg aaaatatgag
      541 cttttttaaa gatagtcctt ggaaaacggt tgttatgcaa tatttaggat tcgctgatac
      601 tcagatcgcg caagtcacgc aactagatca gttattcgat acgatgttga aggatggtca
      661 agtgactgcc accgctactt acgatcaata tttgacggcg ctcagtcaaa tagagcagat
      721 ccggaatgaa aaaataagcg cagcatacgc aacaaaagca caaactgttg ctcagcaaat
      781 gggctatagc aatataagtt attgacagtt aaaacgttga ttcaagcaag gttagcaaac
      841 ggaggaaact atggcaagac gaagaagaaa atcaagaggg aaaaaaatat ttctgattat
      901 tttagcagtt cttatcgtat tagtattagc aattgtagga gtaggagcaa aattatatct
      961 ggatctctca cattctattg agaaaactta cgaatcagtg gaacgaaccc aaggagaacg
     1021 aacgaaacca gttgatctgg acaaacaaga atctttctct gttctattga tggggattga
     1081 tactggagat ttaggtcggg tcgatcaagg aagatcagat acgatgatgg ttgccatagt
     1141 cagtcctgaa gacaaacaga caacgatcgt cagcattcct cgtgatacgt atgtcgacat
     1201 cgtaggtcgt gacacaaaag acaagatcaa ccacgcttac gcattcggcg gagctgccat
     1261 ggcgatggat accgtacaaa aatatgtaga catcccaatc gatcactatg tctctatcaa
     1321 tatgaaaggg ctaaaggaac ttgttgatgc agttggtggt atcgaagtca ataatgacct
     1381 cactttctca caagatggct atgactttac aatcggtaaa atcacattga acggggatca
     1441 ggcattatct tattctcgta tgcgttatga agatccaaat ggtgactatg gtagacaaga
     1501 gcgtcaaaga aagatcgtag aaggtgtagc aaaaaaagta ttgagtttaa acggtgtcag
     1561 caactatcaa tccgttttga atgctctaga gtcgaatatg aaaacagaca tgagctttga
     1621 tgaaatgaaa aaaatcgctt tagattatcg ggaggcattt ggtacgatca agcaagatca
     1681 gctgcaagga gaaggcttta tgcaagataa tatctcctat caaaaagtca gtgatcaaga
     1741 acttgatcgt gtaaaaaaag aattaaaaga tcaaatgaat ctagagaata aataggaaag
     1801 tggagaaaaa atggaagaga caatcaactt ggaagaaatt tttgaaacat tacgcaaaca
     1861 cttggtaaca atcatcatct caatgtttgc tggcttggcc atctcaggaa tcgtaacatt
     1921 tttcatcttg acaccaaaat acagttcaca agcacaattg atcgtgacac tgccacaatc
     1981 agacacagca aatgtcaatg atgtcaatac gaacctgcaa atgatcaata cgtataaaga
     2041 tatgatcgtc agtgatttag tactaaatga agtcaaagat cgtttagaaa cagaagacaa
     2101 tgtgaaaatg actgctggac aaatcaaaga tgcgatctcc gtcaatcagt cacaaaattc
     2161 acaaatgttc tcgatccagg caataagcac gaatgcagtg actgctcaac agatcgctaa
     2221 cacaacttca caagttttcc aagagaacgc aaaagacgtg atgaatgtcg ataaaatctc
     2281 gattatttca ggtgcagttg ccaatacgac acctgtttcg ccaaataata aattgaatct
     2341 agtgattggc ttagtattag gaatgatggt aggcgtaggt ctggcattct tattcgaatt
     2401 acttgatcgg acagtgaaag atgaaaaata tgtgacggat gcattaggat tcccaatctt
     2461 aggaacagtt ccagaaatgt cagcgaaaga attgaacgct ggtatccgta aaaaaggaac
     2521 agctcctgca cgaccaaaag ctacaaacga taaaacagcc ccatcacgca gaagccgctc
     2581 aagagtctag gaggaagaaa aatggcacga acacagaaac aaaaagcagc acaaactcat
     2641 gcagtcagtt tgatcacatt aacaaaccca tcttcaccaa tcgccgaaca atatcgtacg
     2701 atccggacga atatccagtt tgcctccgca gctggtcagc aaatcaaaac gattgtcgtg
     2761 acttcatcag gtcctggaga aggaaaatcc accactgcag caaacattgc agtcgttttt
     2821 gctaaatccg gtcaacgagt tctactagtc gatgcagatt tacgtaaacc cgtcgtctat
     2881 aagacattcc agctgaacaa tgccagggga ttaagtacag cacttagttc atcaggaagt
     2941 gtagcagatg taatccaacg aacgccagtc gagaacttgt cgattttgcc tagtggacct
     3001 aagccaccca acccatcaga attgttaagt tcgccaagaa tggatcagat cctagacgaa
     3061 gcaagacagt tatttgacgt ggtgatattc gatatgccac cagtagtagc cgtaacagat
     3121 gcacagatca tgtcttcaaa aacggatggc actttattgg tcgtacgtga aaatacatca
     3181 cgtaaagaat cattgaataa agcaaaagaa ctgctagaga tggtacaagc acgagtttta
     3241 ggtgttgtat acaacggagc agaacatagc aaagatgctg gttattacta cggaaattaa
     3301 ggaataagaa gagaggagac aagagaaatg atcgatctac attgccatat cctaccagga
     3361 atcgatgacg gggcagaaaa cttagaagca agtattgcaa tggctgaaaa agcgattcag
     3421 caaggcatca cgcatatttt atgcacacca caccacaata atggaaaata cagcaatgaa
     3481 aaatcacaag tcatttctct agtcgcttcg ttacaagccg aattagagaa aagacagttg
     3541 cctttgacgt tattggaagg acaagaagta cgtattaccg gaacgctcat cgaagacatc
     3601 caccgagatg aaattttatt tacagattta gatgatacat atcttctgat cgaatttccg
     3661 acactggaag tgccgttata tgcagaatgg cttttttttg agttgttaga actaggaaag
     3721 acaccagtga tcgtccatcc agaacgcaac gcgcattttc gagaagaccc aaatcatttg
     3781 cttccgttcc tagatatggg atgtttggcc caaattactg cgccaagtta tgttggtgta
     3841 tttggcaaag acattcagaa aacagccaaa acaatggtca aacataatct cgtgcagatg
     3901 gctgcttctg atgcccatgg ggtctctaag cgtacctttt acttaaaaga gtgctatgag
     3961 cagattgcta aggactttgg taaggaaaaa gtagtacaga tgaaacaagt cgcaaaggat
     4021 ctgatcaacg gggatgaaat cagttatcca gtctatgaag aggtaaaaaa gaagaagttt
     4081 ggtttatttt agttctttat tcgtagataa aaaggaaatg aggagagagg gaaagtatgg
     4141 aaagtgaaga tttattatct cgtattagtg aagtacatcc taatcaagtt tggttggata
     4201 aagaaaaagt tgaaaaacga tatatctatt tattttttaa aagaatgatt gatattgtag
     4261 gaagcattat tggtttgatt ttagcttctc ctttgatgtt ctatgtagct tatcgaatca
     4321 gaaaagaaga gccaggaagt ccgatatttt tttgccatac acgtgttggt aaaaatggaa
     4381 aaacattcaa aatgtataaa ttccgttcga tgtgtttaga tgctgaagaa aaattggaag
     4441 aattacttga tcaaaatgaa atagaaggtg caatgttcaa gatgaaagaa gatccccgtg
     4501 tcactaaaat aggtaaaatt atccgtgcca aaagcattga tgaattgcca cagctatgga
     4561 atgttttaaa aggcgatatg agtctaattg gtccacggcc acctttggag agggaagtag
     4621 ctgagtacac gagatatgat cttcaacgct tgtatgtaaa acctggttgt tcaggtttgt
     4681 ggcaagttag tgatagaaat aatgttagtt tccataaaat ggttgagttg gatttagagt
     4741 atattagtca tcgaagttta atgtacgact tgaggttgat tttaaaaacg ttttatgtta
     4801 ttgtcaagcc caatggagca tattagttag ggatagaatg atggattgtt aataaaaaag
     4861 attacacatg ttcatattat cgtttcaaaa gtaataactg taattatgga gggtttgaat
     4921 cacttgtaga aaatctaaaa aaagaaaggt gaatggggca attcagtatc attattctta
     4981 tataaaagaa aatattcgaa attttgggat gataccactc ttaaatataa tgatctaaat
     5041 gctttaatat tggtatatcc gatataggaa ctgacgagct atttagtatg atacaaaagt
     5101 atattgatag ccattaataa attttccaaa aaataatgac agcacaccaa tttttataat
     5161 ttagcttgtt gaatcggtat gttcatggga cggttcaaaa aaagaatcga aaaaataaac
     5221 ggtaaaattt tagtgaatcc tatgtaataa aatttggata gatggaaaaa cagcacataa
     5281 ggaggctgag tttgttgtca tttctgctcc tacaaactat ggtagtgaat gtgttattga
     5341 attagtgatg tctgttactt cagagacatt ggggataatt aacttcacta tacctgtagg
     5401 gtatacaaaa aatggaagaa aaaatattat caatagattt tatttagttc agaattttta
     5461 cgtggaagta aattattgat gataatcttt atccaattag aattattatc gtaggatgtg
     5521 atgatgatag ccgtgaagtt gttcaagtat ttaccaatgt ctacaacgca gaaaattagt
     5581 ttgggttttt cggattggaa aatttcaatg tataaaatca taaatttgct gtaaatagac
     5641 agtttggggt agtaatagcc caataaattg ttcgataaac tcatctttgg ggtgagaata
     5701 gctcaatcat tgaatttcaa acctgccttt ggggtgggat tagaggtcaa tatgtaccta
     5761 cataatactt tttggaaaat gatggtgttg agaatgtaag tacatttcaa tgtgaaattc
     5821 taatatagcc ccaaacgagg tcaataaaaa tgacctaaac tcgtatttct cccctaaacg
     5881 aggaggagat agatatgaaa attgaatgtg ccggcgttgg agttggctgc ttttagtagg
     5941 aatgaacatg gttcgatgag aactgtttca gatagagtgg tcgatgatca caggccttta
     6001 agtcgtttac agatgatgag acttgtaaaa atagagggac gaatggaaaa agatgattgg
     6061 tatagaagaa aagaaaggtg ttcagaaaga cgtaacaatt gatagggaag agaatcttag
     6121 gggacataga ttctattgga ttggacgcag agcacaagat atcttcttct cggctctagc
     6181 tttgattgca ttgagccctg tgatgctaat tacagcgctc gccattgtga ttgacgatcc
     6241 cggtggcagc ccgatttttg tgcaggatag agttggaaga aatggaaagc tgttcaagtt
     6301 ttataaattc cgatctatgt gtgtagatgc tgaagcaaaa ttagaagcct tgttggcaca
     6361 aaacgagatg gatggtccgg tcttcaagat taaagatgac ccaagaatca cgagagttgg
     6421 taaatttatt cgaaagacaa gtatcgatga gttacctcag ctctggaaca ttcttaaagg
     6481 tgatatgagt attattggac ccagacctgc tttaccgaga gaggtggaac aatacggtga
     6541 ctacgaaagg cagcggttgt tcgtacagcc tggtcttagt tgctattggc agattgctcc
     6601 acatcgtaat gaactgtcct ttgaagaatg ggtggaactt gatgtgaagt acatcaatga
     6661 aagaagcttt atcacggact ggaagattat cttcttgact ttacaggctg tattatttgg
     6721 atatggtgaa tgattatata tagtattagg agttgaaata tgtgaatatt attttattat
     6781 cgggtggtag cggtaggcgg ttatggccgc tgtccaacga tattcgtagc aaacaattca
     6841 tcaaactgtt taaggatgaa aatggcgaat atgaatctat gattcaaaga gtttatcgcc
     6901 agattacaac tgttgaccca gatgcaaagg tcactattgc aacaagtaag tctcaggcta
     6961 gtgcaatcca taatcagttg ggagataagg cttcgatttg tgtagaacct tgtcgtagag
     7021 atactttccc tgcaattttg ttagctgcag catatcttca cgatgaactt ggcgtaggtg
     7081 atgatgaaag tgttgcggtt tgtcctgttg atccttatgt agataattcc tattacgaag
     7141 gcgttgaagc ccttgagaag ttggtgcagc agaatacggc taatttgact ttgatgggta
     7201 ttgcacctac atatcctagt gaaaagtacg gttatatcat ccctgaaagt tctaacgaag
     7261 taagtactgt taaggagttt aaggaaaaac ctgacaaagc aacggcagag aaatatttag
     7321 ctcagaatgc tgtttggaat gccggtgtat ttgcgttcaa acttggttac ctgttggaaa
     7381 aagctcacgc aatggtggat tttgaagatt atcgtgattt gtattccaag tatgagactt
     7441 taaccaagat cagctttgac tatgctgtgg tcgaaaaaga aacgagcatt caagtgatgc
     7501 gttataacgg ggattggaaa gatgtcggaa cttggaacat gatggctgaa gttatggctg
     7561 ataatattaa ggggaaagct gtaatggatg atacctgtgt taatactcag attgtgaatg
     7621 agttgaatat tcctattctt gctatgggct gcaaagatat ggtaattgca gcaagtggcg
     7681 atggaattct gatttctgat aaagagcgca gtggctatat gaagccgtat gttgagaaaa
     7741 tcagtacgga agtaatgttt gcagaaaaat cctggggtac atataccgtt atggacgttc
     7801 aggaaggctc catgactgtt aaagtttcta tgcaggccgg acagaagttg agctaccact
     7861 accacaattc tcgcgatgaa gtttggactg ttgtagcagg acagggtaaa gcgattgtag
     7921 atggtatgaa gcagattctt cgtgcgggtg atgtggtgac tattgccgca ggatgtaaac
     7981 atacaatcga agccgtgaca aatctggata ttatcgaagt tcagattggt gaaactatta
     8041 gcgtcgctga caagtataag agttctttga actaaaagtt cgcgaggtag ttattatgga
     8101 gatactaaaa tttcaacccg tgggtaaaga ttatctttgg ggtggagaac ggtttaagac
     8161 ggaatttgga aaaaattgac ttaacaccat taagcttata cgtgggaatg cttagttcat
     8221 ctagacgata actacgtacg gaaatatcaa atatgaagga cagaatggta aaaccgagtt
     8281 gtggtatgta ttggaagcta caccgggggg tgatttatgc ttttgagtac gatgtaacag
     8341 aagaaatgtt acgaaatgct gtgatggaca gatcacttgg gaaacattta tataaagaag
     8401 aagtacacaa gggagatctt ttttatgtca gttcatggta ttggcgctgg agtattagtg
     8461 gctgaaatac aggaaagctc aaatgttacc tatcgagttt acgattatga tcgagtagat
     8521 aagaatgata ataagtgaga attgtacttt gaaaaagcga ttcaggtaat gaatatggaa
     8581 gccactttga aattggagaa aagaaataag ctcattcatt tttatcctgg tggctctcgt
     8641 gaaatactgt gtagatgtaa atactgtgag cccgaaagaa tccaagtaaa gacggggttt
     8701 tcgttctcgg taaaagagga atcttttcaa gttcttttat gtatatcggg ggacggacaa
     8761 gttgagtcgg caaatggtgt tatgaaactc attagatttg taaaaaagat attgtatgtt
     8821 tttgccaacg aatattggaa gatgttaagt gttgagcgat gcggacttac tgaaaattag
     8881 atggggatag agggaggata tctaatgtca cgaatgagat ttatgaacac agaaattgac
     8941 aatcttacaa tgggtgaagt attggtagag gttgaaaaaa tgattcaaga taggagatgc
     9001 ggatatgttg taactccgaa tgtggatcac attgttcagt tggaaacagg aaaagagttg
     9061 caagatgttt ataaaaacgc atctttaatt ttgacggatg gtaaaccatt gatttggatt
     9121 tcaaagtttt ataagacacc aataaaagaa aaaatatcgg gatccgatat attttcttta
     9181 ctgtgcaaga tggctgcaga aaagggatac acaatgtatt ttttaggtgc ggcagagggc
     9241 gttgcggcta aagcggcaga taacctgatg aaaagatttc cgggattaaa tgttgtagga
     9301 acatactctc ctccttatgg gttcgaaaaa gacgaagatg aaatgtttaa aattgattcc
     9361 caaattaaac gagcaaatcc agatatgctt attgtgggtt tgggttgccc taaacaggaa
     9421 aaatttatgt tttataactg tgatagattg ggagtacctg tgtcttttgg tctaggagct
     9481 agtttggact ttgaggcagg gaatgttaaa agagcaccaa aatggatgtc agattatgga
     9541 tttgagtggc tgtttagaat tactcaggac cctaaaagaa tggcaaaacg atatttggtt
     9601 gatgatttaa aaatctttaa attagcacta aaatatcgga aaaaataaac tatattcaat
     9661 gaggacaatg aagtatgatt attacaaaaa caccttttcg catgtctttt tttggcggcg
     9721 gaacggatat ggaagattat tttcgagaaa atggcggtgc agtgctttcc actacttttg
     9781 ataagtactg ttatgtgaat gtgcgtcatt tgcctagatt ttttgattac agcacagagt
     9841 tatcatattc tcgtactgag agagtaacaa atattgaaga tatcgagcat cctgcaattc
     9901 gtaatgcgat gaaaatgcta gatatgcatg aaattcgcct tacatatgaa gcagatcttc
     9961 ctgcacgttc tggtctgggt acatctagtt cttttgccgt aggtatgttg aatgctttct
    10021 atgctttgaa gggcaagtac gctgacaaga agaaactcgt tgataaagca atttatcttg
    10081 aaagagtcct ttgtaatgaa gcaggcggat ggcaagatca gattgcagca gcttatggtg
    10141 gctttaaccg aatcaatttc aactcagatg gctatgaagt attgcctatt attattacgc
    10201 ctgagcgtaa aaagcagctt aacaacaact tgatgatgtt ctttactgga ttcaccagat
    10261 tttcctctga tgttcagaag gcaaataatg tcagcggcac agaggacaaa agagtaagac
    10321 tgaaaaaaat gtatgagctt gtggatgaag cagaagcggt tctgactgat aagaacagag
    10381 atctagatga tttcggcaga ctgcttgatc tcacttggag attgaaaaag gctaccggtg
    10441 gtgcgattag cactggaagt atcgatgaac tttatgaaaa gggcatggct gctggtgcat
    10501 tgggcggtaa acttctcgga gcaggtggcg gcggtttctt ggttttttat gttcagcctg
    10561 aaaaacaaaa tgctgtgcgt tcggcaatga gtaatttgat gtatattccg tttgaatttg
    10621 aaaacggtgg aacacaggtt attcattaca caccggaaat gtatattcca aaataaagaa
    10681 atcagcgagg ataagaatat gaaagttgtt attatggcag gcggtaaggg aactcgcatc
    10741 tcatcggttg caagcgatat tccaaagccc atgattaaaa ttgaaaacaa accggtattg
    10801 gagcacgaaa tcgaatgtct gagagaccag ggattcacag atattattct taccgttagc
    10861 catcttggcg atatcattat gaactatttt ggcgatggtt ctggaatttc accagttact
    10921 ggtcagccct ttgacgttaa aattgaatac tttttggaga aagagccatt aggaaatgcc
    10981 ggtgcattgt ttcgtttaaa ggataatttg accgaagact tcctcctgct gaatgcagat
    11041 gcgatgtttg acgttgattt caaccgattt gtagcatatc accgtgaaaa gggtggcttg
    11101 gtgacattgt ttactcaccc taacagtcat ccatatgaca gcggtctaat cattgcagat
    11161 aaggatggct ctgtagacag atggcttgta aaggaagatt cccgtccaac ttattaccgt
    11221 aacagagtaa atgcgggact ccatgtgatt agtcctgctg ttcttgatgt cgagataaac
    11281 acacctaaga ttgacttgga ccgtcagtta ttaaagccgt tggcaggaac cggaaaaatg
    11341 ttctgctatg atagtccaga atacgtaaaa gacatgggta cccctgatcg ttattatgct
    11401 gtctgtgaag attttaaggc tggaagagtg aagggcaaaa atcttcagaa taagcagaaa
    11461 gctgttttcc ttgatcgtga tggaacgatt aatcaatatg ttggctttct gcgtcatatt
    11521 gatgagttcg aactaatcaa gggtactgaa gatgcagtga aaaagatcaa tgccgctgga
    11581 tatctggcta ttgtaataac gaatcagcca gtaattgcaa gaggtgaagt ttcttttgaa
    11641 gaattggaag agatccataa caaaatggag acacttcttg gatataaggg cgcttatttg
    11701 gatgcagttt attattgccc gcatcatcca cataagggat atgaggaaga gcgcccagag
    11761 ctaaaattcg attgtgaatg cagaaagcca aagcccggaa tgttaattca ggcagctacg
    11821 gacttcaaca tagatttgag tcagtcttgg atgattggcg atggcgagaa tgatattaaa
    11881 gcgggccaag ccgccggctg taagactgca ttggttggcg agagtgagta tggacaggat
    11941 atgaccatag caaccctgag tgaatttgca gataagatct gctaagggat gttttatcac
    12001 gaaaggagag tataaacaat gatagacaat agattacaga aacacattga tttgctgatt
    12061 aaacgctatc ccactcttga agtaatcaag caggatattg ttgacggata cctgattatg
    12121 gaggaatgct atttaaatga tggcaagctg ctgatagcag gaaatggcgg atctgctgct
    12181 gattccgagc atattgcggg tgagctgatg aaaagcttta agacgcctcg ccctgttagt
    12241 agggaatttg cagataaatt gattgcggtt gatcctgtaa agggttctga attagctaag
    12301 aatcttgaat atggtttgat ggcgattcct ctcgttgctc atgaagcgct ttccactgcg
    12361 tatattaatg atgttgatgg cctaggtgtt ttcgcacagc agttgtttgg atttggaaga
    12421 cctggcgatg tattccttgg tatttcgaca tccggcaata gcaaaaatgt gataaatgca
    12481 actgttgttg ctagagctct tggtatgaaa gtaattggct taactggagc caaaggtgga
    12541 gaacttgcaa gggtagcaga tgtttgtgtt aaagctcctg aaacagaaac atatatgatt
    12601 caggagtacc atttgccaat ttaccactgt tggtgtctaa tgttggaaga taaatttttt
    12661 gggaatagat aaaatatcta agcccatatt gaaaggataa aattatgaat gtactattta
    12721 taacaactca atttccatat cctctagata atggcggaaa aattggtgcg tacaacggta
    12781 tcagtgtttt atctagagac tacgatgtga cggtattgtc tttcaccgaa gaaccgcagt
    12841 atgttgaaga aggtgtcagt ttttttcgag agaaatttaa tagtgtaaaa tttgaaaatc
    12901 ctgtgataca tgatgtacac ataagaaata atccaatgaa attggtagaa gctttagcaa
    12961 tagggtattg tctacgccaa ccttatatag tttcaaagtt ttatgattca aaaatgctgc
    13021 agttaataga tgaaaaattt tctaacaatg catattggga tatcattttt attgactatc
    13081 tgaatatgca aagttatggt caatacatac gggagaagta taaaacacaa tttggtaagt
    13141 atatcttaaa agaccacaac atagaatatg atttagtcct acaggaagct gaatcaagtc
    13201 gaggtttaaa aaagaagttg cttcagttag agtataagcg tactcgaaag tatgaagagg
    13261 ccgcagtaaa tagggccgat tattgcttta gtgtgtgtga tgcaaatacg gaagtactga
    13321 aaaagattaa tgacaacagt tatacgatgc ttccaactta tgaaatgctt acaggggtga
    13381 aaaaaaatat agagaagaac acgatcctat atttgggtaa cctttcttgg aaatccaata
    13441 tgcaaggatt agtttggttt ttagagtcaa tttatccaaa tattcaacaa agaattccgg
    13501 atgtaaaaat cacaattgtc ggtagcgggc cagttggaac agattttagt aaatattcag
    13561 gcgtggatta tcgtgggtat gtaaaagata tttcacacat ttatgacgat caagcggtgc
    13621 taattgtacc tttgttagaa ggtagtggta taagaataaa aatattagaa gcgttcaata
    13681 atgaaattgc agttgtatct acattagttg ggtgtgatac gattggcgca aaagatggaa
    13741 gtgagttatt tatagcagat aacgaaaaag attttgcaac ggctgtagtt agactgcttg
    13801 aagacatgaa tttgaatgaa aaagtaagaa agaatgcaaa attattctta aaagaaaaat
    13861 actccttaac ggctagacaa gatgagttta gtgcgataat taacagctaa tatatatata
    13921 agcttatctg atgatgattt ataggaggaa atatatggag atggctgaga gaaaggaaaa
    13981 gaaacttgga aataagaata tcatattatt ttagaaaact cctgttattt tatgtttgtg
    14041 tgattgttgc ggctatgagt taccacctta caggcaattc caatgtagcg tcattaattg
    14101 ctgtagtagg agtagtttat gctattgtaa aggcgtgtaa taacgagtat ctggctatat
    14161 gggttatgtt tgtattaggt tctgatatat gggggatagt gccatatatt aacattggta
    14221 gtggtgtgtt gcattggtca gattttaatg ttatagtagc gatatttctc tgcttgagat
    14281 tcatcaaagt taaagctagg agtagatacg ggattgtcta tagtgtaatg cttatattta
    14341 ttttgattgc atgtgtgcaa tcgcattcaa tctatggaca agatgtacat acaacgctct
    14401 taacagctag agaattgcta gttgtaatat ccttttggcc gatagtaaaa atagtatatt
    14461 cagaaagaat aactaaaaat gaattcattg atttagtgtg taaattcaca agatggacaa
    14521 tgtgtatata ttggtttgaa tggattcttg ttaatatggg attcaatata acctttttac
    14581 agacaggtgc acgctggggt actagaatct atatagatcc gatatttatc attttatatt
    14641 tctttataaa tctatatgcg gttatatata aaagagaggg ctataatagt acaaataaaa
    14701 gtatatggaa ttgcattttt agtttactga catttgttat aatctcgcaa ggcagaagtg
    14761 gtatattata tgtagtaata acctcggtta ttatgctttt aatttcgctt aaaccatcca
    14821 agattattag atttggtata ttaggaattg ccttaattgc atgtctagtg tctgtgaccc
    14881 aaattagaga ggtcgttata tcttcgtttg tagagtctca gagcagtgac acaggtaata
    14941 tcgcatatag aattgctgaa caagattatt ttgaaaataa attagaaggt catgaactat
    15001 ttggagttgg tataccaaac aatcatgatg ccagagctgt agaatattca ggcaaaacaa
    15061 tagattttga gtctaaaaaa tataatccct attatcttga ggacttaggc gcttttgaaa
    15121 ttcgttatag atttggtata attgcatatg cgttatatat agttgcttta gctataagta
    15181 ttatagatgc cggatttcga agagacaaat cggtcgccgc atttgcgggt atggcattca
    15241 tggtgtttat ggcgcttaat tttaatttgc tagcgtatat tacagcaaga ccgttcggat
    15301 ttatgatttc tttaattttg atagaaatat cggcattcaa tgatgaattc atatatattg
    15361 aataggtaag ggagagcaca gatgaattta gatcgattaa agaaaatagc aaatatgatt
    15421 tcaccaatca taaaagtgat aaatgcgccg ttagcgtatt ttagtgggaa atcagattat
    15481 atggagaagg gaatattgtg gcctactgta acaacctact ccaataacag tagaaaagtg
    15541 attcaatata caactttacc taaaaacgta gacaacatgg ctcaaatgca atgggctggg
    15601 gaaagttttg aggacatatg tatagttctt caaggtccag tattagaaga cggtgatttt
    15661 acactaaata ccgttaaaat gtataataaa tactatccta aagtaaaact tgtagtgtct
    15721 acttggatag gattatctga agagacagaa tgcaagttgc gtgaagctgg tgcagatgtt
    15781 gtattatgca agaaacctga aaaaacaggt gcgtacaata ttaatctaca acttacttct
    15841 gcatacgaag gcgtaaaaat ggcgcaaaaa ctggggtgta gttatgcgct gaaaacgcga
    15901 actgatcaaa gactatatgc aaatgatgta ctaaagtatt tccaaacatt attgaatatt
    15961 tttccatctt cggactgtaa agtagtgaat cagcgattaa tatttacgac ttatggaaaa
    16021 tcatttagat atcttccgtt taatttatgt gattttttgg tatacggaga aactagtgaa
    16081 ttattaaaat tatatggtat tcaaagagat aaccgagcat cagactttgg gaaaattatt
    16141 tatactgagg aaaaagagtt taataaaaag atatttacac tactagaagg aaaacaaggt
    16201 gtatctccat atgatgtttt tccagatttt gatgcactat ataaaaaata tatgtttgca
    16261 gaatactata ttgtgtataa ttatttcctg gaaaatattg caagtaatga atcttatggt
    16321 gacttaatgg atgcctatta tagttattta aagaaatatg cagttgttgc tgattcagaa
    16381 aaattgttac tatattggcc gaaatatgtt caatataatg ttaagttcga aaatgaactt
    16441 gatttctatg cgaagttgga ttcaaaaaaa tggatggata tttatgctaa ttatacacct
    16501 tttagtcagt gattatatgg aaaggatgag gtgaataatg aaaatcggaa tagtgactat
    16561 tgttaatggg gcaagttttg gtaacagatt acaaaattat gcgactcaaa aagtgttgga
    16621 aaataacggc tatacagttg agacaattaa taattgtttt gacaaagaaa gtaccctatc
    16681 cattgttatc aaaaacgcta tttatacatt atttaagttt ataccgcatt tcaaaaagtc
    16741 aaaaagtatc tggaaaagaa tgtatacatt ttatcaatgg gacaagcagt atatagatta
    16801 ttctcatcgt aaaattgatg catctaaaaa aaacagcttt gtgagtataa agaatgatta
    16861 tgactatttc ttggttggta gcgatcaaat ttggaatcca aaatatgcag ccaataaggg
    16921 atttgaactt ttatcatttg ttccaaatga aaaaagagtt tcattatcaa ccagtttggg
    16981 agttccatct ataccaagtg atttagaaaa attatatgtg acagagtgga ataagtttaa
    17041 atcaatatcg gtacgtgaaa atcaagcggc aaaaataatt gaggacttga caggcacaac
    17101 tgcggctgtt cacattgacc caactttaat gttggagcgt tcggaatggg aagcctttca
    17161 aaaaaaacca gacaatattg atgaaaatta catcttgtcg tttttcttaa ctaatccgcc
    17221 taaggatact gttgatgtat tagataaggt cgctaaagat ttgaaaatag gtgttctcac
    17281 cttagatgcg tcttgggaat attttcaaga tattactccg aatcattttg tttatttgat
    17341 ttcacatgca agaatgattt atacagattc attccactgc acagtttttt cattgctatt
    17401 tggaaaaccg gttgtggtat ttgaccgttt tgatagtgaa aaaatgaatt ctaggttaag
    17461 tacattgtta aataaagtaa ataaagcaca tttttgggta ggaaaaaaag ctgatgaagc
    17521 aatgattcgt gcaatagcat ctgaacctga atatgacata gataagctga tggtatcaga
    17581 gagggaatgt gtaaaagctt atcttaaaga gtatttacag taaaattttg aaatgggatg
    17641 aaaatatgga gcatttaagt gattgttttg gtaaaatgaa gattgttacg acttcatgcg
    17701 caagagaata ttttaaggat gatttggata aatcagagta ttcatgtttt gttgattctc
    17761 gagcagctat gtttttcgca atgggacaag ctttagctaa aagaaggaat gtagttgtaa
    17821 tgcttgctga tgaattgaca tcgtgttata cggcactaac agaatgtgca tttcaacaag
    17881 ttgatttaat tgtgtttgct tttcagacag tcagacatga aattgattta gcatctttga
    17941 agaattgtgg ttgcaatcta attaactgta gcgcccaaga cgatattgat agagttgtgt
    18001 ccaacactaa ggggttaaat cagacaacag taattaaaat caatatgaat tgtgagtcgg
    18061 ataaagatca tatatgtgag tatatagacc tgccagacat acctgttttt ttccacggta
    18121 gcttatactc acctgcaagt aaaaagaaat atgagcagta tggacaggta tcgaagtatt
    18181 taggctatct cgtgggggga aaagatgcaa tactcataat ttctcacaat gagtttttaa
    18241 acgatatcag tgtatggatt aattattatt cttttggaga aattcaaccc aaaattatta
    18301 tatttgacag tccgaatgac tatcaatata aatggctgtg tgacttagaa tgcagtgtag
    18361 ctcattcaac caaccgattt ttgtctgagg atttagcctt attgcaaaat aacggaattt
    18421 ccattgtgtt aagaggtgat aattatgata tcgtcagtta aaaatgttca aattttagta
    18481 tctttattaa aacagcataa tattaaagat atagttatct cgccaggtag tagagatttt
    18541 caattggtgc atagtgtaga aacagacagt ttttttagaa cctatacggt tgtagatgag
    18601 cgcagtgctg ccttttttgc taatggactt tctatggcga ttgataagcc cgtgtgtgta
    18661 tgttgtactt cttcaactgc ctcttcaaat tatatggcgg cagctaaaga tgcttttgct
    18721 aatggcatcc aacttgtact tcttactgct gatagagatt accgccgctt atatcagatg
    18781 gaagatcaga tgattgatca ggtagatatg tatggggctt atgtgcgttc taacgttgat
    18841 attcctattg ttaaggattc tgatgatgaa tggtatgcta ccagaaaaat aaatgaagca
    18901 atattggagt taaatcatgg cgttaagggt cccgtgcaga ttaattatca attaatggat
    18961 ttaagtgcgc cgtttgttga gaccatgcca gagtatcgta aaattacaag atatcaagag
    19021 gatgatttac tgtcatcagt agagattttt aaacagaaac tattatcaaa aaagagaata
    19081 atggttttat gtggacagca ggaagaaaat aatttaagtg ccttattgga agagttcttt
    19141 attaaatata atacaattat aatcaaggat aactattcta atatacacgg tgaacacttt
    19201 attaagactg ttctagtaac agaaagaatg agtgtaaatg catttattga ttattgccca
    19261 gatttggtaa taactattgg taaacatgta tggtcttttg tgaaatatac tcttagagat
    19321 aaaaagctta aatttgagca ttggcggata tctgaggatg gtaagattgt tgatccgttc
    19381 aacaagctaa catctgtctt tcagtgctca gcggaatttt ttatggagac tgtcactgct
    19441 ggtgtgaata gcaataataa tcttgagtat tataatctat ggaagacaag attatcaaaa
    19501 gtttgctatc cagagttagt ctatagcaat ttttatgcaa tttcagaact agtaaaaaaa
    19561 attccagata gtgcattagt tcattctagt attttaaatg cggctagatt gtatgacttt
    19621 gtatctgatg ataaagcatt actcagtttt gctaatttag gggctgatgg tattgatggt
    19681 tgtttaccaa catttttagg tcaggcagaa gcagataaaa ctcgacctgc gtatttaatt
    19741 tcaggagact tgagtttctt ttatgctatg aatagtttat gtggtgacat tccagataat
    19801 gcacatattt tccttattaa caatcattct ggaagtgaat tccatacaaa ttttggtaag
    19861 ttttacaacg gatcattaag tgttgataag catatagctg caggacatat ttcaaacgca
    19921 aaggattggg cattagaaaa taatataaaa tacattactg cggattctaa ggaaagtctc
    19981 aaatcggggt tggatgtatt tattaataca tttgacagtc ctgttttatt tgaggtcttt
    20041 acagatccgg atacggatac gtctgttctg gaatcttttt atagtataaa taaggtaatc
    20101 acaccaaaaa tgtattttag aaaggcgtta gatattataa aaaagcattt acacattaag
    20161 tagatgttta ttgcgaggtg aaacaaatat ggcaataaaa tcttatatta aacggttatt
    20221 gctttatatc cgtcatggag atcccaaaat aaatttagat gtgagttatt tatctgaagg
    20281 tgcaatgctt gctggtaaga ctgtgataat tacgggtggt gcaaaaggac ttggttttgc
    20341 aattgcaaaa tcatttatag ctcaaggcgc aagcgttatt attacaggaa gagacatgga
    20401 ttcgttgaat aatgctaaat gtcagcttgg agatatgtgt tctatcaggg cgtttgatat
    20461 aactgatgct aaaatgtatc gaacgttttt tgaagatgca tacgagacct ttggacgtat
    20521 tgatatactg cttaataatg ctgggatctc gttacacgaa gatggattta tgagtgttac
    20581 tgagaaaact tgggataagc aaatggatac aaatttgaaa ggtgtttatt tctttacaca
    20641 ggaatttatt aagtttgtta aagaaaagaa tcaaatgcaa gcaaatatta ttatgatgtc
    20701 ctcagaaaga ggcttgtgtg gtgatagtat tccgtatgga ttatcaaagg ctgcaattaa
    20761 ctctttagtt gtaggcttgt ctaagaaata tatttctgag ggaattaggg ttaatggtat
    20821 tgctcctgga gtaactgcaa ccgctatgac tggtatttct gaaaagggta atttgtataa
    20881 tcctgcaacg atcggttata gatattttct cccagaagaa gttgctcaag ttgctttgtt
    20941 tttggcaagt agtctttcaa actgtatcag tggtgaaatc atagcctgtg accaggggca
    21001 atatttaagt cgaaattggg ggtaataact tgggaatatt attaaaaaaa tataatagcc
    21061 ttagtgagcc tgcaaaagca tctatttggt ttacactttg taatgtgttg caaaaaggaa
    21121 ttctattttt gactacacct atttttacaa gaatgctttc aactgcagaa tatggtaagt
    21181 atacgatttt tatatcgtgg tattctatta tagcaatttt cacaacgttg aatttatctg
    21241 caggtgtcta taataaagga ctaattaaat acgagaataa atatgcatta acctcgtcat
    21301 ttttaggatt atcgtcattt atttcccttt gtgcattgat gctatacctt ccatttagaa
    21361 cggttataaa tgggctactg gatttatcga cggagtttgt catattgatt cttattgaat
    21421 caatatttga gccggctttt ttgctttggt cagttaagga acgatttgat tacaagtatc
    21481 aaaaactagt actcatcaca gttcttatgg ctgttttaaa tccaggtctc ggtattatat
    21541 taatcttatc atttggggag tatgctattt ggagagtacg agcttatgtc gtggtaaatg
    21601 ttgtagtggg gatgtttatt ggcataggaa tactggctaa gggtaagaaa ttatttgata
    21661 aagagtactg gacatatgcg ctcagattta atttgccatt aataccacat tatttatcaa
    21721 tgacattgct gaatcaggtt gatcgcctta tgataaatag tatggttgga gctagcgagg
    21781 ctgcgattta tagtatcgct tacactatat ctagtatgat gaatatcata acaacagcta
    21841 taaacggttc ttttattcct tttacataca aagcaattaa agatggcgtg tatgaaaaaa
    21901 ttaaatccgt tgctaatcaa ctattagtgt tgatttttgt cttgtgttcg tttactatgc
    21961 tgttcgggcc agaattgatt tgggttgtcg gaggagaaaa atatatggat gctgtttgga
    22021 ttattcctcc agttgcggca tcagtatttt tcatgttttt atatccgctt tttggcaata
    22081 ttgaatttta ctatgaaaag acaaactacg taatgtttgc atcttgtgtg ggctctatcg
    22141 caaaaattat ttcaaactat gttagtattc cccgttttgg atatatttcg gctggttaca
    22201 cgacattgat ttgctatatg ttgttttcct ttgcccacta catgttttat aaaaaaattc
    22261 ttagagaaaa tggtataaaa gaagatatgt ataatattaa aaatattata tttctttctg
    22321 tcttaatgat
//
LOCUS       DACCVZ010000044        21632 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.044, whole genome shotgun sequence.
ACCESSION   DACCVZ010000044 DACCVZ010000000
VERSION     DACCVZ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21632
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.044"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            212..1018
                     /gene="proB"
                     /locus_tag="IVW63_001683"
     CDS             212..1018
                     /gene="proB"
                     /locus_tag="IVW63_001683"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAP7859961.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1015..2262
                     /locus_tag="IVW63_001684"
     CDS             1015..2262
                     /locus_tag="IVW63_001684"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAP7859962.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2338..2682
                     /locus_tag="IVW63_001685"
     CDS             2338..2682
                     /locus_tag="IVW63_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859963.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2799..3125)
                     /locus_tag="IVW63_001686"
     CDS             complement(2799..3125)
                     /locus_tag="IVW63_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7859964.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3498..4700)
                     /locus_tag="IVW63_001687"
     CDS             complement(3498..4700)
                     /locus_tag="IVW63_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7859965.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4817..5332
                     /locus_tag="IVW63_001688"
     CDS             4817..5332
                     /locus_tag="IVW63_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP7859966.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5531..5977)
                     /locus_tag="IVW63_001689"
     CDS             complement(5531..5977)
                     /locus_tag="IVW63_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAP7859967.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6024..7502)
                     /gene="msr"
                     /locus_tag="IVW63_001690"
     CDS             complement(6024..7502)
                     /gene="msr"
                     /locus_tag="IVW63_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAP7859968.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7856..8485)
                     /locus_tag="IVW63_001691"
     CDS             complement(7856..8485)
                     /locus_tag="IVW63_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP7859969.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8469..8933)
                     /locus_tag="IVW63_001692"
     CDS             complement(8469..8933)
                     /locus_tag="IVW63_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7859970.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9420..10688)
                     /locus_tag="IVW63_001693"
     CDS             complement(9420..10688)
                     /locus_tag="IVW63_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAP7859971.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10919..11656)
                     /locus_tag="IVW63_001694"
     CDS             complement(10919..11656)
                     /locus_tag="IVW63_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7859972.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11723..12292)
                     /locus_tag="IVW63_001695"
     CDS             complement(11723..12292)
                     /locus_tag="IVW63_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAP7859973.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12420..13292
                     /locus_tag="IVW63_001696"
     CDS             12420..13292
                     /locus_tag="IVW63_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP7859974.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13634..14506
                     /locus_tag="IVW63_001697"
     CDS             13634..14506
                     /locus_tag="IVW63_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7859975.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14503..16461
                     /locus_tag="IVW63_001698"
     CDS             14503..16461
                     /locus_tag="IVW63_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7859976.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16712..17563)
                     /locus_tag="IVW63_001699"
     CDS             complement(16712..17563)
                     /locus_tag="IVW63_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7859977.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17686..18153
                     /locus_tag="IVW63_001700"
     CDS             17686..18153
                     /locus_tag="IVW63_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAP7859978.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18416..18898)
                     /locus_tag="IVW63_001701"
     CDS             complement(18416..18898)
                     /locus_tag="IVW63_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP7859979.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18998..19861)
                     /locus_tag="IVW63_001702"
     CDS             complement(18998..19861)
                     /locus_tag="IVW63_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP7859980.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            complement(20358..21545)
                     /locus_tag="IVW63_001703"
     CDS             complement(20358..21545)
                     /locus_tag="IVW63_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HAP7859981.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT         6489 a         4472 c         3917 g         6754 t
ORIGIN      
        1 aaactactcc tattctaaca tatccgaggc tgtaaaagac tttctttaca aattcttcaa
       61 gaaattctgc tatcttaaag taaaccatta attcgttctt tttccaaacg actacaagtt
      121 gtacaaaaaa actatttttt acatgacttt actcgtcaaa acaagtagaa tagaacgaaa
      181 ttaatgagtg gatatttgat tgaggtgtca catgcgtaaa gaaattaaaa atgcaaaacg
      241 aattattgtc aaagtaggaa caagtacatt gatttatccc aatggaaata tcaatcttgc
      301 ggcaatcgat cagttagctt ttgtcctttc tgatcttaga aatcggggaa aggaagtgat
      361 cttagtctca tcaggagctg taggcgttgg tatgcataaa ttacatttgt cagaacgtcc
      421 gactttgatt cctgaacagc aagctgcggc ggctgttggt caagccgaac tgatgaatat
      481 ctataatcaa agattcagtg tatataatca acagacggca cagatcctcg tgacaagaga
      541 cgtggtagat tatcctgaaa gtcgtaaaaa tgtgaggaat acattggaac agcttttgat
      601 tatggacacg atccctatcg tgaacgaaaa cgatactgta gcagtggatg aattagatca
      661 tctgacaaaa tttggcgata atgatcagct gtcagccatc atggcaaaac ttgtcgcggc
      721 agaccttttg atcgtccttt ctgatatcga cgggttttat tcagataatc cgactacaaa
      781 tcccgaggct cagatgtatc gctatatcga taaaatcgat gaaaagattc tggcacaagc
      841 aggtggtgct ggtagcacat ttggaacagg cggtatgcag agtaaattaa aagccgcttc
      901 taggatattt gaagcaaaca gcgcaatgat tttagcaaat ggaaaaaatc cggcaattat
      961 ttttgatatt cttgcaggaa aagaagtagg tactttattt aaggaggact tgaaatgact
     1021 gacttgatgc aattaggaca acaggcaaaa gatagcgcgc aacaactagc acttatgcct
     1081 acaaaccgca aaaatgagct acttgttcaa atggcacaaa ccatcaaaaa gaatcaacaa
     1141 gcgatcattg aagcaaatca taaagactta gaaaaagcag tcgaaaacaa tatcagtgaa
     1201 acgatgcaag accgcttgca gctgacacct gagcgaatca atgccatggc tacagagatc
     1261 gaaaaaattg cttcgttaga cgatcctatt ggaaaagtag atgagatgtg gacgaacacc
     1321 gacggattga gaatcggcaa aaagcgcgtg ccactaggcg tgaccggcat catttacgaa
     1381 tctcgtccaa atgtcacgac agatgcagct agtctagcat tcaaatcagg gaatgccgtt
     1441 atccttcgcg gtggcaaaga agcattcttc tcgaatcaat tattagtcca attattgcag
     1501 caagtactgg tcagtgctgg cgaatctcct tatgccatcc agtttgtcga tgatacttct
     1561 catgaaactg caggacagtt gatgcgattg acagaatact tagatgtgct gattcctcga
     1621 ggcggagcaa aattaatcca acgagtcaaa gaacaggcaa cggtacctat cattgaaaca
     1681 ggtacaggaa ataatcacgt atatatcgat aaagaagcac agttatctat ggcagtgaac
     1741 atcatcgtca atgcaaaagc ttcccgtcca tctgtctgta acgcggcaga aacattgctg
     1801 atccattctg agatcgcacc ttttttcttg ccagctattg aaaaagaact ggtagaacac
     1861 ggggtctctt tacgtgcgga tgctcgtgcg ttagaatatc tagagacggc tgctttagca
     1921 gaagacacag attgggatac tgaatatcta gattatatcc ttgctgtcaa agtggtcgat
     1981 tctttggatg aagcaattgc acatatcaat cggcataata ctaaacattc agaaacgatc
     2041 gtgacagata gttatgcggc tagtcaacgt ttcttaaatg aagtggacgc ggcggctgtc
     2101 tatgtcaatg cctccactcg ttttacagac ggatcggtat ttggttttgg tgcagagatt
     2161 ggtatctcta ctcaaaagtt gcatgcccgt ggtccaatgg ggttaaatga attaacttcc
     2221 acaaaatata tcatttatgg cgatggacaa atccgcgaat aatgtttcgt gtgaaacatt
     2281 attcccgcct tttgcctttt ttctgtaaag gttctatcca actagaaagg tgtcaatatg
     2341 tttgaaattt taatgatttt ttttatttac cttatttctc tgaatatcgc tgcttttctg
     2401 ggagtcggta ttttatccct tttctttcaa ttcaaaaaac gaagcatagg gagtcaacgg
     2461 gaaaaatggt cgcagtattt tgacaaaatc gggcaaaaag ggctggttac acgcttgcac
     2521 attagttaca tggttgcatt atgcttatta gcgacaatca attactattc ttttttcgat
     2581 cattcaatcg cttatacgat tacgctactg attgctggga tttttcactt atcttataaa
     2641 tatcagctga ataaaaacca cttgaatcgg actttccgct aaaaaatatc cgtacgataa
     2701 gtagagtgcc ttgaagatcg gcaaaaaact gccggacttt ttagaggctg tgacaaagat
     2761 tttgtcacag cctctttttc catataaacg gcgttcgcct accagctgcc tggtaaatct
     2821 gtttcctctt cgttaagaag cgaaaatccg tcaaatgttt cgccatcata ataacgaagc
     2881 agctcatcca tggacaagtt catcgttttt tctttttctt cttccgctga ttcagccagt
     2941 agctgttccc gatacacctg atacatacca gctatttttt gctgcatcgc ttttctagtt
     3001 tcaccttccg cattgattat tggcaattct ttgatatagc cacgataaat caaccgatca
     3061 tctgaaaatt caatgggtaa ttcaacgagt gtcaacccga cttcctgaaa atattcttcc
     3121 agcatctatt atccccccat tctttttctt aaatgaattt tagcttacct actgaaaatt
     3181 ttccagtttc attattttga gaaaaaaagg gaatgtgaca aaaatcgtgt cacatcccct
     3241 ttttccgaat aaatggtgtt cttctgccaa ctcctcaatc ataagtcaca atattcaaca
     3301 aacatgagaa actgtttttt gaaattgttc cttgtgattc agagttaaac gacagtctca
     3361 caacctcttg gtaaacggcg ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg
     3421 aaaaatatga gaagctattt ttgtttggct gttcttatga cttgatgcag gacagctttt
     3481 tcacaacctc tgatttctta ttcttcttca tttgtagcaa aataattacg gtgataaatg
     3541 atacaacata cactgataag aacaatggca cctgcaaaat aaaacgcata gctttcacca
     3601 atatgttcac caatcacacc tgcaataaat ggtgctaaag ctccaccgaa aaagcggaca
     3661 aaactatagc tggacgaagc aacgtttcgt tgcagacctg gtatttccat agcaatcgtc
     3721 gtcaacagtg tattgataat tccttggaaa aatcctgcta acacaatgct gatcggtaca
     3781 aggactggca tagaagttcc agctcctaat aacagcaaac aaataatgaa taagacaaat
     3841 gctgctaaaa ttgtccgata agtcgtaaac ttccgctcaa gagccggtgc aacgaaaatc
     3901 gaagcaatag ccagaagcac accccagcca aaaaatacaa aaccgacttc taattcagaa
     3961 tagccaatca ataaaaatgg cgcatacgca agtaaagtaa agaatccgaa attatataac
     4021 aatgcgatta gtccaactga acgaagttta tgattgctta acgctttgac accttcccaa
     4081 aggcctactt ttctctttgg tttctcagtt tcaggtaaaa gtaccgctag ggctataaaa
     4141 ccgcaaaaca tcaaaaatgc taccccaaaa aatggataac gccatgaacc actgcccaag
     4201 accccaccga ctagagggcc aacagccatt ccgcagccaa gtgctgcttc atacatcatg
     4261 attgcttttt ctgtgttacc aactaaaata ctgacgatcg ttgctaaagc agtagagaca
     4321 aataaagcat tcccgacacc ccagccggca cgtaacccaa tcagcattcc gatattccca
     4381 gataatccgc caagaccagc gaatacaacg atgataaaca atcctgtcat caatgttttt
     4441 ttcaaaccga tccgactaga taagaaacct gtaaatagca tcaccacacc agtgactaac
     4501 atgtaactag taaataacag ggtcgtttca gctggcgtag cgtttaactg tgcagcaatc
     4561 gtttttaaga ttgggtctac tagacccact cccataaaag cgatcataca ggtagctgct
     4621 acaactagcg ctgaactttt cccctttgtt tcttcatttg tttgttcttg tatatctatt
     4681 tgattctcca atatttccat ccctttctct ctattagcat catacatgat ttattttaca
     4741 tgtaaatatg cacatgtaaa acgtggaaac tttactgtga tataataaag aaaataagac
     4801 gagaggtagg atttttatga atactttagc ctatatatta ttatgcgtgc ttttatccaa
     4861 accacgttct gggtatgaat tgaagcagct gatcacaatt ttttgggaag cccatcacag
     4921 tcagatctat acaacgcttg ccaagttaga ccagcagggt tatgtgaccg ttttggacaa
     4981 agacgagcac tctcaaaaaa agatctacca cttgactgat gaaggacgtg ctcttgtaga
     5041 ggaatggatc aaagaggaaa ctcccgctcc tacgcaaaaa gatgaatttc tagcaaaaat
     5101 ctatgctttt tcgacgctcg ataaaacaac agctactgga ctgctattca ctagagaaca
     5161 acagctgaac aaaatcatgc aaaaaaatca aaaaaaattg aatgacctct cgctagacaa
     5221 gaaacaagaa tttggacgtt atgttgtgat ccagcgcaga attatgcttt gtcagcagga
     5281 actccaatgg tgtcagcaag taagagaaca aatgcagcag ttttttgagt aagggataaa
     5341 cagaaccttt ctagaaatat ctattgaaga gcaaattatc ttcaataaaa gagcaataca
     5401 gttggaaaag aaaaagcgat ccgaacgaca ggccaaaacc tatcgttcgg atcactattt
     5461 ttctagaact gcattcaaga gactatgaca aaaagcatgc caaggccttt tttcaaataa
     5521 cagtgttcca tcattcatta ctttgaattg cttttagcac acttcttgaa agcgggccaa
     5581 cgatgatcaa ctgcaacggt aaagcggcaa tcacattcat tttccaagca ttcatataag
     5641 cagagaataa ttgatcaggt attccttgtt ccatgatcac accgaataaa gacatacatg
     5701 tcaccattcc taaaaccatc aagcatgaaa tagttaagat catttggacc ttgctttctg
     5761 gatttactgg tagtttaaag gcaatttttt tcgccagcac accgatgatg aagacatcca
     5821 aaatgaaagc caccacgaat ccaggcacta gaccaatcaa caaacttgat aaatgaagat
     5881 cttgatgcag ccataaatta tacgcgctca tccccaagac catcaaaaaa cacatcattg
     5941 ttgtaaaaat tattccttct tttttatttg taggcaatct gtaccactcc tttaaatttg
     6001 tcacgaaaat catcgtagca catttaaaaa tttctcgtaa gtactttttt tattttctgc
     6061 ccttttattt cataaacttc atcagccgta cgctcgacaa agtaagaatc atgagaagta
     6121 aacaaaatcg ttcccggata tatttgcatt agcttctcta aagcttcgat cgttgccata
     6181 tcaataaaat tagtcggttc atctaacagc aacacattac ttggcttagt aaaaagcaaa
     6241 gcaatcgtca gacgggtcgc ttctccccca cttaatgtac ataacggttt cgtcaaagtt
     6301 tcctgagcaa accctaagtg attcagcaaa ctacggacaa gcgattctga aaactctgtt
     6361 tgtctcatga caaaacgaat gatggattct tcagatgtca tttgataacc cttttgctga
     6421 tatacttgaa agcttacttt cggagagaga aggattcctt ctccttgttt gcggatatgt
     6481 tctaataagg ttgtcttacc tgaaccattt tcaccgacaa tcgcgatttt tttacctaaa
     6541 gaaaactgaa aatcaccatt taccagtaat gttctcccac ttctttccaa ttggacattt
     6601 tgtcccatga tgggatagcg gctgtggagt tcaagagatt ttggtactgg aaaacggatt
     6661 tgtttcatct gctgcggctt ggttgtttct cctatttttt ggagtcttct ctctaatgtt
     6721 ttcgcattct tttggatggc tttttgtaca ctgtcttttt gtttagagga agacaaccga
     6781 tccggtctga tttgttgctt tttcttttta ctggacactt tttccaactt ttccgcttgt
     6841 tttttctttt cttggatcga tttttccaat cgttttttct ctttcatgat cgactctgct
     6901 tctcgtagct gagtcttttt ctccaattcc ttttgagtga gataggcact ataattcccc
     6961 gaaaactctc ggatttctcc gtcttttact tcccagattt tcgatgctag ctcatctaga
     7021 aaatagcgat catgactaac aaaaaccagc gtaccataat aataacgaag ctcttcaatc
     7081 agtcgatcaa tactttttct atctagatgg gttgttggct cgtctagaag catcccttgt
     7141 tcataagaag aaagaagacg tatcaactcg atctttcgtt cttcccctcc gctccatttc
     7201 cgctctgaag tttcttccag tcttaactgg aaatgactgg ctaattccaa atttaggtcc
     7261 tttgcttcag cgagataggt taattgaggc aggtagttga aggtgatctc tgtttggatt
     7321 ttcccatgat cgggaaaaag ttcaccggct attagtttga gcaaagtcga tttaccgaca
     7381 ccattttctc ctatgatccc tatacgatct tgctgataga cacgaagaga atcaatagat
     7441 agttctagct ggttgccaaa gctgacttgt agatttgtta tatttactgc taaattttcc
     7501 atatgtttta cactcctatt tcatgtaaaa caacaattat cgatactaaa aaagagcaga
     7561 aaaatctgtt tgcaaaaaaa ctgcatcaca tcttttccta ctctgaacga aataactatg
     7621 actaaatcac caaatctgtc atagctttca cctattctac tgtcgttcga aaaaatggac
     7681 atactccatc catgaaattg ttgtttatac atgtcttttg aatttattta gttgttattc
     7741 aaaagttcga aacgtaattt catcgatgca gtcatttttc cgacctcctt ttttattagg
     7801 ttaccacaca cgattcaaaa aaagcaatag ctactgaata gtaactgaaa accttttatt
     7861 cgaacgtagt gatcttttct ggtgctaaac gaacagactc gtaaccttct tctaccgctt
     7921 ttcctattga taaaataata actggaacat aacggtcttt atccaaacca aatgcctctg
     7981 ccaactgatc tgcttcgact ccaccaattg gatttgtttc atagccatga tcacgcgcaa
     8041 ctaacatgaa ttgcatagcc gctaagctag aatcgacttt gactacatcg ttcatttctt
     8101 ctcttgaaaa actcttgtaa taaggaatga tcgcagctaa ttgttgatct ctgacttctt
     8161 ttggcatctt ccctgattcg taagcttggt tatagatttc ttcgccatat tcgtaacatt
     8221 gcatatcgcc aaaaatcatg accattgcag aagaagtatc attttgtctc gtattgaaac
     8281 ggatcaaagg acgcaagatt tcttttgctt cctcgctttc agcgaccaca aagcgccatg
     8341 gttgcatatt gacagaagaa ggtgcagtcg tcgcttcttt gatcatttcc agcatttctt
     8401 cgtgtgggat tttgtatgtt tcatcatata cgcgaacgga tcttctacca gtcataattg
     8461 ttgaaaaatc atttttttgt tccattatta ttaacctctt tcgtttctgt tgttatattg
     8521 caaagttggg tattcaattt atctaaaagt gttagaaatt gtttcatttc tacatcgctg
     8581 aaagccgggg atagcacgga acctgtatct ttatggtcca tttcacaatg ctcgattttc
     8641 ttctgggctt tttctgttag cgctacatac acttcccggt tgttctgagg atttctctga
     8701 cgcgaaacat agccatttgc ttccaatacc ttcagatgac gagtaactgc tccttgatca
     8761 atctgcaact tttcttgcaa actgctttgt agcaatggat tttcttcttt cagtctcatc
     8821 atgatctcgt atctagtaag acttataccg atattttctt caaagatctg gacgattttt
     8881 tgatcggcta atttgatttg atataaaagg tgactaatct cttctaaaga cataatttcc
     8941 tcctttctaa taattgactc gtcaacgatt gacttgtcaa taatagaata aaaaaagaaa
     9001 aaagtcaaag aatcagctgt gtaataaaaa aaacgctctc aatagaaaag tatagagaaa
     9061 agaaattttt tgtagaatga acggaaaaaa tgataaagaa agcacaacgc taaaaccaag
     9121 attattgatt cttatcaaac tatagaagat agctcttctg cagtagaaaa ttttacaccg
     9181 ccaaaaattt ccgaaatcgc cttttgcaag aatcccgtcg aatattagaa attggatcag
     9241 tatgcttaaa cagtaataaa aaagttatga caagatgttg tcacaacctt ttttgagtaa
     9301 acggtgttca aaaacttgca tctgcggtaa taagttcaac caaacaaaaa acatgaaaat
     9361 ctgtttttgt ttggctgttc ttactacttg atgcagggca gctttttcac tacctctttt
     9421 taataaccat aaaatcctat tccttcatat ctccagccca tcggtgttag ccaatctctt
     9481 tccttagcac tcaaggtata gtgatgggta ccagtttttt catttggatt aaatagtcga
     9541 taaattggct tggaaccacc agaataaaaa cttagacctt cataacgcca accgattttt
     9601 gttaaagagt tgatctcaga ttgtgccatt gtgtaatgat ggtctccact gtaaggattg
     9661 tataaacggt agacaggttg tccgctgttt ggtgcttgcc aagcaatccc ttcatattcc
     9721 cagcctacag ttggcagata atttttttct ccggcattca atgtatataa atgttctcct
     9781 gtatgacggt tatacagacg atacatcgga gaagttgaag ttggtgctgt atcatactgt
     9841 gtcagattat aggtttcgat tacattgttc aatgtagaac cataattagg cgcagtggca
     9901 taacgacctg ttagccaagc cgtagcatct ttgtaagagt tcgtattgct tttccatgca
     9961 ccggaatagt agtaaacgcc tggctgaaaa gaagtcgtct tcaataccgt tacgttatct
    10021 tgcaatgatt ctttgtacga aggatatttt ctaaaagcgg cattcaccgt aatccattgc
    10081 ccattcacat attccgaagt aggcatcgta acagattggc cattatagct tcctttaatc
    10141 ccaaatagat tgtaattagg ggcagaagcc aaagtactgt tcccccagcc actttcaacg
    10201 atggcttgag caatcatgac tgatgcatat aagtcattgg cacttgccaa actttgtgca
    10261 gttgaggcaa tactatcaat gaacgcttgt tgagaattag cagatgagcg agcataaaaa
    10321 gcatagccag tatagttttc gaattcagac aaatctgctt gatgggtatg tgtcaatgtt
    10381 tgcccatctg tcaattggtt cgtgatttct tctgcattct ctggattgtt ctgagcttct
    10441 gctgatgtac tgtcttcggt ttgtgtttgt tctgttgttt cagttgttgg ttcttcggtt
    10501 gaaattgtat tttctgagac agtagctgac tgcaaagtac tctctgtatc gttttcaatt
    10561 cctgtttctg aagaactcga tgtctgagtt gcgacagttt ctgtcgattc ttcagctagc
    10621 actgttgtgt tggcaactgc tagatttcct aaaagaataa cgctaaataa taaattcttt
    10681 gctttcatct tttttctcct ttgaattatg aaacttttcc taaataacag tgtaactaaa
    10741 aaagtaaaag caagtcaatg tccatattta aataacattt gtttcttttt gataaatttg
    10801 ctttttctac ataaaaagac gtaaatgaag aatattcttc tccattcacg ccttaaattg
    10861 atggtcgttt gaataactat ttaacaagta attctctttg gatattatcc gttatggatt
    10921 atacttcctg tgtcgtcgga cggataatca tgttactgac agacatccgg tctggcgttt
    10981 ctatcgcaaa tgctacagca gaagctatat cttcggaggt caatccccat tctttttgcg
    11041 cttcatgaag ttcaagagca gcctttttgt cgctgatggt ttgatataat tcagtttgaa
    11101 cagctcctgg agagatgatc gtagatttga tgttattttg ccgttgctct tgacgtaatc
    11161 cttccatgat tgcacggaca gcaaattttg ttccgcaata aacggcggaa tcaggataaa
    11221 caacatgtcc cgccacagaa tcagttgaaa tgatatgccc agatttttgt ttttccatga
    11281 ttggaagtac ggcggaaatt ccatttaaca cacccatgat gttgatatca agcatatttt
    11341 gccattcatc acggtgacct tcaactaatg gagcggttgg catgattcct gcattattgt
    11401 acaatacatc gattcgaccg aacttttcca tcgctaaatc gataactgct tggacttgtg
    11461 caaaatctct tacatctgct gtttgaatat atagctcagc ttctggtaaa gattctttta
    11521 ttgcttttag gcgatcttct cggcgtgcag ctataactag tttagcccct ttttctgcta
    11581 atagcttcgt tgttgcttca ccgattccgc ttgaagcgcc catgatgaca atcacttttt
    11641 ctgataaatc attcattcta ttctcctcct gttttgaaaa atctcttgct tatactcact
    11701 atctcttatt tcatcttact gttcaaataa tccgttcgac aggtttgacg attttggcag
    11761 ggattcctgc aacgatggta ttgtctggga catctttcgt aacagttgca ttcgctgcaa
    11821 caatggcatt ctcgccaatc gttacgcctg gcagaatagt tgctcctgct ccgatccaag
    11881 catttttctt gatgtggatt ggctttacta acaagcctct tcgttctttt ggatcggtta
    11941 gatggttcac cgtgatgagg ttgacacgag gaccaatcaa tactgaatct tctaaacaga
    12001 tgccacctaa gtcaacgaac atcacttgac gattgataaa gacatttttc cctatactaa
    12061 tatgtttgcc gaaatctgta taaaaaggca gcagaacagt caccgtatca tctactttgt
    12121 cactaatgat attttctagc cgtttgcgga tatctgctgg ttcatggtac ccagtattca
    12181 gcgctgctaa aggctcttcg ttttcagctt ggatctgatg gatcacttca aagagcggat
    12241 ccgttactcg aatctcttta ttgacgattt gtttttcgat gaggcttgtc attttgctcc
    12301 ctccttttat ccttacttta taacggacgg cttatcatgt ctaatactta taaaacatac
    12361 ttaactattc cttttaacta tacttagtgg tatgcttttt taaaaacagg agggaaaaaa
    12421 tggatattcg tatactgacg tattttttag cagtagctag agaaaaaaat atcagccgag
    12481 cagcaaaatc tctgcatatc acgcaaccta ctctctcaaa acaactgaaa gatttagaag
    12541 aagaacttgg tgtgacactt ttcactcggg gctcccgaga gatacagttg acggattctg
    12601 gtcgatatct ttattcaaaa ggaaaagaaa tcttgtcgtt ggtagaaaaa acggcgaaca
    12661 atttaacaaa tgacgcaatc atctctggag aaatctacat tggcggaggc gaaactaaag
    12721 caatctcttt catttctgat agccttcatt cgttgatcaa ggcgcatcct gatatccagt
    12781 ttcatttata tagcgggaat gcagatgata tcatagacaa actggatagc ggattacttg
    12841 attttggact cgtaatcgaa ccgacaaaca aacaaaaata ccagtcattt cgactgccag
    12901 cccaagatcg ttggggactt ttgatacatc gaaatcatcc tttagcaaag caaaccgtca
    12961 tccatccgca ggaactgaaa actgttcctt tgatcatttc ccggcaaacg tcagtggaca
    13021 gtcaactagc tgaatggcta ggtttcagca tagatcagtt atcgatcgtc ggaacatata
    13081 acttattgta caatgcttct ttgatggtcg ataacgggac ttttggtgca ttagctctag
    13141 atgggatcat caatacttat gggacggaaa aaatattcat cccactcgat ccgccattac
    13201 aagcttcact gaatctcatt tggaaaaaag accagcctct ttctcctgct gctcgtaaat
    13261 ttttagatgt cctaacggag aaatacagtt aagtagagtt tttttccttc gctttcagct
    13321 ttttaacaac gaataagata agcaaaagat ccaacgatta aataacataa gtttcttaat
    13381 ttatttcttc cttttatttc tgataattcc agtaaattac tataattata aaaaaagaat
    13441 tgacaaaaca taactgtcta tataaaattg attacgttaa caataattcg tttcatgtga
    13501 ctggatcata ctaggcatga aaaatctctg aggaacatgg tttccctagg aggtttttcg
    13561 tgtctatttt tgtttggccg caatcaactg gtctagcaaa cgtgaaaacc aaatcttcaa
    13621 aaagggtgcg cgcatgaaaa tcaaaaagat ctttaatcaa aatgcagtat tggtagatga
    13681 cggtggacag gaaaaagtag ctattggaaa agggattgga tttgacagaa aaagaaatga
    13741 tttgattttt gatcgtgatg tcgaacggat atttgtcatg gaaccagaag gtcaaatcaa
    13801 gttgcaaaat ttacttaatc agattgatga acgcttttta tttgcagcag aaacgatcat
    13861 tgatcatgcg gaaactgttt tgatggaaaa gttgaatgaa catgtattga tcgctttgac
    13921 cgaccacatt gctttttctg cggagaacat taataacggt atcgtcatcc gcaacaaact
    13981 tttaagagaa atcgaagtgc tttacagtga tgaattcagt attgctcaat gggcagtaga
    14041 gtatctgaca aaagagcttg ggattccata tacttatgac gaagcaggat atatcgcaat
    14101 ccatattcac agcggacgaa gcggtcggaa caataaccat cgcagtatcc gtgaagtgac
    14161 gattgtatct gacatcatcc atttagtgga atcagaattg gaaacagata tccattcaga
    14221 accattttca ctgaattatt caagactggt gaatcattta cgactgcttc tacaacgaac
    14281 ccatgcgcaa caatatgctg ttttagacac ggaaatcgta gaaatggtca aacgaaaata
    14341 cccagaaagc tataagattt ctaaaaaaat ccgtgtgttg ctgaccaaag aataccagct
    14401 cgcgatcacg aaagaagaac tgggttactt ggccatccat atcgagcgtt taagaagcgc
    14461 aatcgtacaa acaaatgtta acaatcatga ggaggaaaaa aattgaaagc atatctacaa
    14521 cgaatgggac gttcccttca acttccagtt gcggtcttac ctgctgctgc tttactagta
    14581 gggatcggaa actggtgggc atcttatagt aacgacattg tcgctcattt tttacaagct
    14641 ggcggtaacg cagttttagg tcaattacct ttgctgtttg ccgttgggtt agcactaggg
    14701 atgtcagtgg acaaatcagg tgctgctgcc ttggcaggtt tggtcgcatt tgaagttcca
    14761 gtaaatgttt taaaaactga ttcagtagct actttattga atatcaaacc agaatcagtt
    14821 gatccatctt ttgctcagat cagtaacgta tttattggta ttattgccgg attgattgcg
    14881 gcagctcttt ataatcgttt ccacgaagca aaattaccga tggctttatc tttctttagc
    14941 ggcaagcgtc tagtgccaat cttggctgcc tttgtcatgt tgctgatcag tgcagtgcta
    15001 ctgctcgtat ggcctccggt ttactctgct ttagtttctt ttgctaaatt cattttgagt
    15061 ttaggctggg gtggtgcagg tctttatggc ttcttcaacc gtttactgat ccctacagga
    15121 ttgcatcaag caatgaactc cgtgttctgg tttgacgtag caggaatcaa tgatattggt
    15181 aaatttttgg cttctgaagg aacaaaaggc gtaacaggaa tgtatcaagc tggatttttc
    15241 ccaatcatga tgttcgggct tccagcagga gcatatgcta tttacagaaa tgcacgtcca
    15301 gaaaacaaag caaaaacagc ttccttgatg ctagcagcag cttttgcttc attctttact
    15361 ggtgtgacag aaccacttga attttcattt atgttcgttg cttggccatt atatgtcttg
    15421 catgcaattt tcactgggat ttctttagca gtgagtgcat tcttccattg gacagcagga
    15481 tttgccttta gtgccggatt tgtcgattac ttcctatctt tgaaaaatcc gattgcgaat
    15541 cagccattga tgttgatcgt ccaaggatta gtaacagcag tgatttacta ctttggcttt
    15601 aactttgcta tcaaaaaatt ccatctgatg actcctggcc gcgaggaagc agatctttca
    15661 gatgacgata ctgcaacgac taattcagac aataaatatg cggcacaagc aagcaaaatc
    15721 tacgctgcat taggcggagc cgacaatgta acttcgatcg ataactgtac tacacgcctt
    15781 cgtttgcaag tcaaagatac aggcctgatc gatcaaaata aaatcaaagc cactggcgta
    15841 cctggtatga agatcatcga cggaaaaaat gcgcaagtca tcgtaggtac agaagtacaa
    15901 ttcgttgcag atgagatggc aaaactacat ggtggtgctg cagcacgacc tgcacaaaca
    15961 aacaccgtgg ttaaaacaga aacatttgcc ggtgaaacga tcgaacaaga tatttacgct
    16021 atcgcaaatg ggaaactgat tccaatcact gaagtttcag atgatgtatt cgcggaaaaa
    16081 atgatgggtg acggctatgc tgtattacca gaaaatggag aaatcttctc tccaatcgct
    16141 ggtacgatca caaacatttt cccaacgaaa catgctgtcg gaatccaaac agatgctggt
    16201 atcgaagtct tgcttcatat gggcatcaac actgttgact taaaaggcga accattcact
    16261 ttatatgtag aagaaggtca aaaagtcgca agaggtcaat tgattgcttt agttgatctt
    16321 gccgctattc aatctgcagg caaaaacacg gatatggtcg ttgtattcac aaatggcgac
    16381 aaagtccaaa gcttagaaat cgaacccgca cgtgatgtaa aagcaaatga taaaatcggc
    16441 tctgtttcca acaaagcctg agccatcgtc ttccccagac ttttttatcg ataaacaaac
    16501 aggagctgag acaaaaatct tgtctcagct cctttttccg aataaaaacg gcgttctcct
    16561 gccaactccg cggtaataag tccagctaaa cgaaacatat gaagagctat tttttatttg
    16621 actcttctta ttacttgatg cagaacagct ttttcacaaa atttttcttc atactcaaaa
    16681 ctaatcggct ttttcacaac ctctttatac attattcctg atccaatatt tcttttaatg
    16741 ctgcttcaag agaagttaat ggttttccca atactttttc taaatcatca gaggaaatag
    16801 ctaactgatc ctttttaata tcatgttgga tcgctaaaaa catgtcagct gcttcttgag
    16861 ggaatccggc ttcttttaga ttttcgacaa acgctgcatc acttgcttca ataatttcta
    16921 actctttacc tgtcgcacgc tctaatgcct tggctaattc ttcatagtca gttagattgc
    16981 cggataattc taagatttct ggagagtcac tttctactag tacttttgct gcagcttctg
    17041 catattcacg tttcaatgcc caacctgttt ttccatttcc tgcagcataa acgaattgac
    17101 cagtttttaa agcctgccca atgataggta attcattctc tacataccaa ttattccgta
    17161 aaaatgtatg ggaaatacct gaatccttaa tcattttttc agtgaattgg tgatctggcg
    17221 ctaatacact gatcgagtga tcggcatctg caaaacttgt ataagcgata taagataccc
    17281 cagctgcttg tgctgccttc actacattct tatgttcggc ttgacgattt cctggaacgc
    17341 cagagacaaa aagcaatcga tctattcctt tcaacgcttc tttcattgag tctaaatcat
    17401 cataatcacc aatacgtata ttaaatccag cttctttcag tgcttctcct ttttcttcac
    17461 tacgtactag tacatagatt tcattttgtg gaaccatctt ttttaagaat tccagcgcat
    17521 aaccaccaaa acctccagtt gctcctgtta ctaaataatg catatttgcc actccctatt
    17581 ctttttattt gttaagattt acagctgtac atttataaat tacaccttta tcataaagag
    17641 tgtggtaaga taagtcaagc aaaaaaaatg aaaggatgac aactgatgaa gtattctctg
    17701 caatttagtg atgcaatcca tgtacttgcc tatattgaaa tgtttcaaga tacccgatca
    17761 ctttctagtg agatgattgc cagtagtatc gaaacaaatg cagcaaatgt acgtaaaatc
    17821 atgagtcagc tcaaaaaatc cggtttgatc tttacaaaaa ccggaaaacc gcagccttcc
    17881 cttgccaaaa gtccagatca gatttcttta ctagatgtct atcgcagcat cgaaggtaat
    17941 acacagctta tccaagtcga tccaaaaaca aatccaaatt gcgtcgttgg tgcgaatatc
    18001 caagaagctt tagaagaaag ctacgctcgg ctgcagaaaa aggcagaaga agaaatggct
    18061 aagatcacac ttgatagtct gatacataaa atagccgttt tggaaaaaga aaaaagacca
    18121 gaaaacacag gcctcgtaga gagattttta taattctctc tactgtgcct gcatttttct
    18181 gatcggaatc gtctacataa attcttttat tctccggggg acaaaagcct tgtcatgccc
    18241 ctttttcctc tctaatgctc aggtcaaagc gctgaagtca tgacgtcttg ataaacggtg
    18301 ttcaagtagc tgaccctcgg cattagttct gaaaaatgca aaatatggaa agctatttcc
    18361 catttttcct ctctaatgct caggtcaaag cgctactttc acgacctcta tattatcatg
    18421 gtttattgac taccggtatc cagatttctc ccatatattt cccgttggta actcccattt
    18481 cgactacagc atttggaccc ccaacatagg cgtaatcttc tacttctctt aaaacatgcc
    18541 caaaggccgt attcgtcaaa tcatttctta attcttcagg cgattctgct aaagcgctta
    18601 caacaagata cgttcctttt gggaatggga tgattcgcgt agtgtttgga acatcctgac
    18661 tcgtttgaac accgacatag tacatcattt tcccgttata gggttcgttg actgtaaaga
    18721 aataatgatt ttcagcagct tgtttcaatg catctattgt tccattaccg ataacttttt
    18781 gctcaaatgc ttgtttctct gcagccaaac cgacaaaatc cgtattgcta ctcttcaatt
    18841 ccacaccaat acccgtcacc gtaaaatctg gtttttcttc gatcctatac tttgccattt
    18901 ctcccaccct ttctattata ttaagttcat cttacataaa attaaaggga aatgacacga
    18961 ttacgctctt ttttctaggg atatttttat tttttaacta tttttttgct ttcactgcaa
    19021 tccaaatctc actgtaaaca ttactgaaat cctctcccca ttttgtaaaa gagatctcgg
    19081 gagcttcgac taacccataa tctgaagaag gaagccattc tgcatagatt ttcccccaag
    19141 tatcttgtaa agtttgggga aatggccctt tattaggaaa aatggcccaa gtgtgttctt
    19201 ctatagcaag catttctaaa tcagcgtacg gattttcttt tgtcgtagca aagccaatca
    19261 tgtgcatcaa actgcccttt tcttccaagc ggtctccatc aaatccataa gaaacgttga
    19321 ttacttgatt tggatataaa tctcctaact tatgcatctc ttccctttga gtctccgtga
    19381 tcgtctgcgc taacttttgt atttcttgat tgactccttc aaatttgaca ggaacttttt
    19441 tcgccacacc tgccacataa aactgttctt tcttttcgat acgaaattcc atcgattttc
    19501 ctcctctgac atcaataaaa aatgtcaagc gtggaaaaga tttttgtatg ccgtatctgc
    19561 tgatttctga aggcagatat cctgaccaat cacgaaaagc tcttgaaaaa ccttcgactg
    19621 tttcatatcc atatctaaac gccgtttctg tcactcttga tccatctaga agatcgcgat
    19681 tagccaaagc caatctacgg tttttgatat agtccattag cgacatccct gcaataaacg
    19741 taaagatgcg ttttaattga tattcagaga ttcctgtatt ttcggctatt attttatagg
    19801 aaagtccttc tgtcaaatgt tcttcgatgt aatcgatcaa ttggttcaga tctttaagca
    19861 tatttatctt cctccttgat tgccttttta tcatattatc aaagaaagtc aattacttga
    19921 tgaatcagga accaatttag tcagatgtag aaaatgttgt atggatctaa agaaaattct
    19981 caagcagcgt ttcgtaacgg ataattggta ttatctgcct atctatgttt tacctttaga
    20041 aaaataaatt ttggggaaga cagattctaa gtaaacaaag cggtaaaaat atcttttatt
    20101 cccttagtta atccgcttac tacctactgt acaaagcaaa ttgttgttca aactgctgat
    20161 cagaacgctg cttggatttt tctttgcagt caagtccaca atcttgtgta aaagttcaac
    20221 ctcatcaaaa gcacaatgtt ttgcgttgtg aacctaactg ccatgccttt ctttctgagg
    20281 agagaggtca ggagcagtag cgcagcgact cttgatgtct ctcctcagaa agaagagact
    20341 cgcacaggtt catggtgcta aatgttattc gaattaaatt ctaaatattt tcgtggagaa
    20401 gccagccact cagtgtcttt ttccatcaaa agtgttccaa ttatccgagt gatggaattg
    20461 atatttggaa aaatccgaat cactcgttct ctccggcgaa tctcttcgtt caaccgttcc
    20521 aacacattgg ttgtacgaat ccttcggcgg atattttcag gaaaagacaa aatttgaata
    20581 gcatcttcaa agccgttttc taaaatgtcg caagcagcac ttaattttga atcacaacca
    20641 tatttttcca agaagtgctc ttttctttca cgtgtcaatt caagttcaga ggctttaaag
    20701 atactcttca actcgtcttt tacatcagaa gaaactttct ttggcagctt atcaaaaata
    20761 tttctcaaaa agtgggcttg gcatctttgc cagctcgcac ctaaaaagtt cttgcgaaca
    20821 gccttaacta accctttgtg tgcatcagaa atgaccagtt ttacaccgaa caaacctcgt
    20881 tgaacgaacg attgaaaaac ggtatcccaa ttatcttccg attcgccgtc ttgaacatca
    20941 aaaccaagaa tcgtacgtcg tccatcagaa tcaatgccga taccaatata tacacctttt
    21001 gagacaatac gatgattttc ccttactttc atatacaggg catcacacat gaaaaatgga
    21061 tattccgagc cttctaggct ccggtttctc cactcaaaaa caaatggatc caactgtttc
    21121 atcagatttg aaacgaatga tttagaaaca gtcgcaccat ccgttagcag ttcaactgtt
    21181 ttagttactt tgcgagtgga gacaccagaa atgaccattt caatcatggc agcgatcaaa
    21241 gctttttcgc ttcgctgata tctttcaaag atagtaggac taaacttacc gtctctggtt
    21301 cgtggaacat gaagttctaa cgtaccaatt cgagttgtaa acgaacgatc gtagtaacca
    21361 tttctttgtg attgccgttc ttctgaacgt tcataggcat ttgcctgaat atattgattt
    21421 cgttgttctt ccatcagctg attaaacatg atagtcataa gtgtttttgc ggtatcattc
    21481 gcaccgcttt cgtttataat tgcttgaatt tcttcgcttt caaaagtaaa atgtacttga
    21541 gtcattgata tcagtcctat tcgagtatgt tttctgcaaa aaacattgta ctcctaactg
    21601 agatcaatgg cttttttgat gcttcacttt ta
//
LOCUS       DACCVZ010000045        21406 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.045, whole genome shotgun sequence.
ACCESSION   DACCVZ010000045 DACCVZ010000000
VERSION     DACCVZ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.045"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            86..787
                     /locus_tag="IVW63_001704"
     CDS             86..787
                     /locus_tag="IVW63_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP7859982.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1396..2412)
                     /gene="tsaD"
                     /locus_tag="IVW63_001705"
     CDS             complement(1396..2412)
                     /gene="tsaD"
                     /locus_tag="IVW63_001705"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAP7859983.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2409..2873)
                     /gene="rimI"
                     /locus_tag="IVW63_001706"
     CDS             complement(2409..2873)
                     /gene="rimI"
                     /locus_tag="IVW63_001706"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAP7859984.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2880..3422)
                     /gene="rimI"
                     /locus_tag="IVW63_001707"
     CDS             complement(2880..3422)
                     /gene="rimI"
                     /locus_tag="IVW63_001707"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAP7859985.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3406..4230)
                     /gene="tsaB"
                     /locus_tag="IVW63_001708"
     CDS             complement(3406..4230)
                     /gene="tsaB"
                     /locus_tag="IVW63_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAP7859986.1"
                     /translation="MYYCTSFAFGIFILRIKKYATMEGENVIAERIKYMITLGIDTAN
                     QTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAIDQLFADLQISPKDIDRIAVSDGPGS
                     YTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAANCIGVDNIIVPMFDARRKNVYAGAY
                     RWKENRLETVLEDVHISASDLFTQLQKLNEAIYFVGSDCHKFFSEIKEILPSAMINTV
                     PAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKRVEAEEKWLETHTPGDESYVEKI"
     gene            complement(4319..5299)
                     /locus_tag="IVW63_001709"
     CDS             complement(4319..5299)
                     /locus_tag="IVW63_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP7859987.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5323..6807)
                     /gene="galT"
                     /locus_tag="IVW63_001710"
     CDS             complement(5323..6807)
                     /gene="galT"
                     /locus_tag="IVW63_001710"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HAP7859988.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6819..7808)
                     /gene="galE"
                     /locus_tag="IVW63_001711"
     CDS             complement(6819..7808)
                     /gene="galE"
                     /locus_tag="IVW63_001711"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAP7859989.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            8056..8223
                     /locus_tag="IVW63_001712"
     CDS             8056..8223
                     /locus_tag="IVW63_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HAP7859990.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(8285..10096)
                     /locus_tag="IVW63_001713"
     CDS             complement(8285..10096)
                     /locus_tag="IVW63_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HAP7859991.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(10093..10458)
                     /locus_tag="IVW63_001714"
     CDS             complement(10093..10458)
                     /locus_tag="IVW63_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HAP7859992.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(10621..11016)
                     /locus_tag="IVW63_001715"
     CDS             complement(10621..11016)
                     /locus_tag="IVW63_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP7859993.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(11034..11996)
                     /locus_tag="IVW63_001716"
     CDS             complement(11034..11996)
                     /locus_tag="IVW63_001716"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HAP7859994.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(11996..12208)
                     /locus_tag="IVW63_001717"
     CDS             complement(11996..12208)
                     /locus_tag="IVW63_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HAP7859995.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(12229..12927)
                     /locus_tag="IVW63_001718"
     CDS             complement(12229..12927)
                     /locus_tag="IVW63_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAP7859996.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(12947..13489)
                     /locus_tag="IVW63_001719"
     CDS             complement(12947..13489)
                     /locus_tag="IVW63_001719"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAP7859997.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(13621..14625)
                     /locus_tag="IVW63_001720"
     CDS             complement(13621..14625)
                     /locus_tag="IVW63_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAP7859998.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(14622..15611)
                     /locus_tag="IVW63_001721"
     CDS             complement(14622..15611)
                     /locus_tag="IVW63_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAP7859999.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(15608..16414)
                     /locus_tag="IVW63_001722"
     CDS             complement(15608..16414)
                     /locus_tag="IVW63_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860000.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            16580..17536
                     /locus_tag="IVW63_001723"
     CDS             16580..17536
                     /locus_tag="IVW63_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7860001.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(17613..18131)
                     /locus_tag="IVW63_001724"
     CDS             complement(17613..18131)
                     /locus_tag="IVW63_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP7860002.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(18219..18368)
                     /gene="rpmG"
                     /locus_tag="IVW63_001725"
     CDS             complement(18219..18368)
                     /gene="rpmG"
                     /locus_tag="IVW63_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP7860003.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            18596..19042
                     /locus_tag="IVW63_001726"
     CDS             18596..19042
                     /locus_tag="IVW63_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAP7860004.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(19237..21132)
                     /gene="asnB"
                     /locus_tag="IVW63_001727"
     CDS             complement(19237..21132)
                     /gene="asnB"
                     /locus_tag="IVW63_001727"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAP7860005.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         6435 a         4548 c         3696 g         6727 t
ORIGIN      
        1 ttctaatgtt ggtatgttaa aactttacaa attctttaaa aaaagtgaca ataaatatag
       61 tgaacaataa ggagaggact ttttaatgcg tgttaataaa atcgattttc acttttcaaa
      121 actcagatat caacctgatt ttgaacattt ctcggatgaa gagttccaac agatcaagga
      181 acatactgtt cttcgttctt ataaaaaagg acagatcctt ttcgacgatg gtgatcccag
      241 acaacggttg tatatcttga ccaaaggact cgttcgttta gaacgttatg atgaaagtgc
      301 aacttattac tactatgact atgtgaatac aaataacctt tttcctatgt caggaatgtt
      361 tggagaagag acctacactt atacagctca agcgatgact gatattgaaa cattctacct
      421 tcctgtttcc tactatgaaa aattagcacg aaaaaatccc gaacagttga tctatatgat
      481 acaaaaaatt tctaaagtag ttgaaataca tgaattgcgt atccaaatcg gattgacctc
      541 tagcgccttt gaccgggtaa aacaaaattt attcattttg aaagaagaat tgggcgtacc
      601 aacaaaagat ggtcatatca ccattcctta tccgatcacc ttaaaagaat tagcagtgaa
      661 tagcggcacg acacgtgaaa ctgctggaca agtaatcaaa caactacgtg attccgggct
      721 gttagattat gacaaaaagc gttttacttt ctgtaagaca gctactactc cagctatgag
      781 agaataacgc gaacaaaaat aagcagtgac cctgataaat atcagggtca ctgcttattt
      841 tcctccctaa aacttctgaa agatccggca gttttagatc actggacaag actcaaagat
      901 tttctatgtg tgtttcagtt atgtaatatt cactgtttgc aaaaaatact gttagattaa
      961 ctagatgaag cgtcttgtcc tcatccgatc tagattattc gatattcctc gacaataaac
     1021 gattactcag tgagggcaat cagaggaacg gataatgata aataagctgt aaaaaatagc
     1081 aaaataacaa taatgattaa aagtatgtaa aaaatagggc tttgacaaaa acgtgtcaca
     1141 gccctatttc gattaaacgg tgtgtacctg tcaactcttc ggtcacaagt cataatgttc
     1201 ataaacatga ggagctgttt tttgaaattg ttccttgtga atcagagtta aacgacaggc
     1261 ttacgaactc ttgattaaac ggcgttcaaa agcttgcata cgcggtaata agaacagcca
     1321 ggtcaaaaac atgagaagcc gtttttcctg ggctgttctt attacttgat gcagggcagc
     1381 tttttcacaa cctctttatt cagataaaac caagcttgga tcagcattca actgatagct
     1441 agcaaaattt cttttttgca tttccacatg tgctgctgct ccaatcattg cagcattatc
     1501 tccacaaagt cgaagagggg gaatcactag ttctacctca gggagtttag ctgccaaagc
     1561 atcctgcaat ccttcacgca acccttgatt ggccgctaca cctccagcta taatcagttg
     1621 cttgactgga taattttgac aagctcgaag tgttttagta atcaatacat cgatcacact
     1681 tgcttgaaag ctagctgcta aatcattttt gtctagatct tctccacgct gttgtgcatt
     1741 atgcaccaaa ttgataaatg cactttttaa tccgctaaaa ctgaaatcat aattatcttc
     1801 atggatcatc gctcgcggaa aatggtaatt atcttttccc tgatgagcta gctgatcgat
     1861 ttcttttccg cttgggtaag aaagacctaa tactcttcca actttgtcat aagcttctcc
     1921 tgctgcgtca tctcttgtct ccccaatgat ttcatatgat ccatcttctt gcatatagac
     1981 taattctgta tgtcctccgc taacaagaag tgccatcaat ggaaactgga atggtttaac
     2041 cagacgggct gcatagatat gccctgccat atggtttaca ggaataagcg gcaattggtg
     2101 tgcccaagca aaagccttag ctgcagaaat accaatcagc aacgagccga caagtcctgg
     2161 tccataagtg acagcgactg ccgataaatc ttctgccgac acaccagctt ctaccagtgc
     2221 atcttccaag cataaggtga tttgttctac gtgatggcgg ctagctactt caggtactac
     2281 gccaccaaaa cgtttatgac tgtttatttg agaagcaacg atgttagata agatctctgt
     2341 tccatttcta acgaccgcta cactcgtttc atcacaactt gattcaatcg ccagaatcaa
     2401 ttcttcattc atttcatcgt ctccgttttt aactttctgc tcataatgat cgcatcttcc
     2461 gtcggattgc gataatatga tttccgttta cctaatatac gaaacttttc tgattcataa
     2521 agttttcttg ctgcttcatt agatagacgt acttctaaaa aaacatgcag cgaatctttt
     2581 atttgttccg taatcagtaa ttgtaacaaa tgccgtgcat gcccttttcc ttgttctgaa
     2641 actgcaacag caatatttgt gatctcgact tcatctatta ctttcgagta tccaataaag
     2701 ccacagatct ggttatcttc agctaaaagc agataatcag agtgaggctg ttggatgtct
     2761 gccaaaaact gcattttcgt ccaaggtgaa ccatgtggat aagcattttc gctaatcatc
     2821 catacgcatt ctgccaagta cgcttcatca aaatcttttt ttctgcaaat caactaatct
     2881 cactcatttt ctaaaagttt tatcatatcc aacgcatctt cttttgtttc agtgtaatat
     2941 ctttttttga tcgttgttgc ttgaaacccc aatttccgat aaagtctttg tgcatcttga
     3001 ttactcatac gcacttctaa tgacatcgtc tcacagcgat tcattatagc aaagttctcg
     3061 atttcgtcaa taagcagcga accgattcgt ttacgctgat atgccggtcg aacggcaata
     3121 ttcgtgatat ggcaatctaa accgaacgct cttgaaccga taaaaccaat cattcttcca
     3181 ttatcaaaga tacctagata tagatgagga agcggtgact tcaattctga tataaaggca
     3241 ctttttgtcc atggcaattc gccattatag acttctcgtt cgacatccag cagctctttg
     3301 atatcttctg tagtcaattc tcttagtacg taacgacgat cgatttgttc gactgttttt
     3361 tctgtataaa tcattttatc ttgaaaaaag cttctggcat acgctctaaa ttttttcaac
     3421 ataactttcg tctccaggtg tgtgcgtctc caaccatttt tcttctgctt ctactcgttt
     3481 taaatagcga ggaagaaaag cttgtttctc tgcaactggt tcaactaaag cacctaattg
     3541 agccacagtt acaccacttg gaatatccca tgctggaact gtattaatca tcgcactagg
     3601 caatatttcc tttatttcag agaagaattt gtgacaatca ctcccgacga aataaatagc
     3661 ttcattcagc ttttgtagtt gtgtgaacaa atcagaagca gaaatatgta catcttcaag
     3721 tacagtttct aatctatttt ctttccagcg gtatgcccca gcgtatacat tttttcttcg
     3781 agcatcaaac atgggcacaa taatattatc cacaccgatg caattagccg cgatggtttt
     3841 cagactagat actcctacta gctctttatc taatgtataa gcaatcgttt ttgctgtcgt
     3901 tacacctata cgaagccctg tataagaacc gggaccatca gaaaccgcga ttcggtcaat
     3961 gtcttttgga cttatttgaa gatctgcaaa caattggtcg attgcaggca tcagtgttac
     4021 actgtggttg cgtttgatat ttgtttgtat ttgtccaaga atttgttcgt cttctaccac
     4081 accgatcgcc aaagtttggt ttgcagtatc tattcctaat gtaatcatat atttgatcct
     4141 ttctgctatg acattctcgc cttccattgt agcatacttt tttattctga ggatgaaaat
     4201 accaaaggca aaactagtac aataatacat gattatctgc tggcgggcaa attttgcccc
     4261 ttcctgaaac acaaaaaagc tgcggtatca ctccattttc ccacagcttt tccatctttt
     4321 atttcgttga ttctcgaata atcaactctg tttccacaat aatctttctt gaaaccggtg
     4381 ctttggaatt acttaattga agaatcgtct ccactgctag ctctcccatc cattcggtat
     4441 aaacttttac agtagaaagc gagggcgtta catatttcgc tacactgaca tcattgaagc
     4501 ccatcacaga aatatcttct ggtaccacta aacctttttc ttgaatcgct ttcagtgcgc
     4561 caatcgctaa tgcatcatta gctgcaaaaa gcgcatcagg aacatgcgga ttcgttttta
     4621 aatattgctt cactgcttga tatcctgact cgacagaaaa atctgcttcg ataattggac
     4681 cttcgtcgta gcctttttct gccaaaactt gttgaaatgc cataattctg ggatctttta
     4741 gccgctgatg gtttttcttc gtatattctg ttccagcaag catagcgata tgttgcgctt
     4801 tatgggagac aaagtgttca atgacttttt gaacacttga cttaaagtcg acaactagag
     4861 agtcgattcc ttgagaagtg ccgtcagaat ctaccaaaag caaggcattt tgggatcctt
     4921 tcatttctaa taactgagct tcgtcgaatt ttcctagtgc gatcgttcca tctgccggaa
     4981 gatcactaat ggaatcccac gtttctttca ataaagtaac gtttgcttct tctgcctttt
     5041 tttcgattcc taggcgaata gataaataat aaagatcttc aagctcttcc gtatcgtcgt
     5101 accactggat caggcgaagc gtttgcttag tatttgctgc atttttacga tgtttcgtat
     5161 aatttaagcg ttctgctgct tcaaaaattt tttgctttgt ggctaagcca acggaaagat
     5221 caggatcata gttgagaact cttgaaacag tagcaggaga aactcctgcc aactgcgcaa
     5281 tgtctttaat tgttgccatt tgtctctcct ccttttttac gtttataaaa tcgcagtaaa
     5341 tcgttcaaac gctgcctgtc ctttttcatc tcgcttgaat actccagcgt cttccagtac
     5401 acgtgcaaaa acctgaccta cagatttttg tacgacatcg gtgaccgtat ctttcgtcaa
     5461 atcaggatgt tcttttttta attgttctgc ccacggacga tgatattcag ccatctggtt
     5521 ttcttctcct aataagaaat gctctacttc tactagttct ggtttcaaac gaggtggtaa
     5581 aacagcaagc cccattactt cgatcaaccc aatgttctcc tttttgatat gttggacatc
     5641 tttatgtgga tgaaaaatcc catcaggatg ttcttctgaa acattgttgt ctcgaaggac
     5701 aaggtccaac tcaaagtaat tgtcccttct tcgtgcaatt ggcgtaatcg tatggtgtgg
     5761 tgtaccatct gctgaaaaag ctctgataga tactgtttca tccgaatatg ctttccattt
     5821 ttccaatact gagttagctg cttcaataag caagtttttc tctgttgatt gcaaacggat
     5881 cacagacatc ggccatttca cgactcctgc gatgacttgc ggataatctt ctagtttgat
     5941 aagtttttct atcggtgctt ttgccatagg aaattcatga cgtcctgcct gataatgatc
     6001 atgagaaaga atcgatcctc caacaattgg taagtcagca ttcgaaccaa caaagtaatg
     6061 aggcaagact tcagtaatcc gaagcagtct agcaaatgtt tcctttgtga ttttcatcgg
     6121 gcggtgttgt tctgataaaa tgatcgaatg ttcattgtaa taagcataag gggaatattg
     6181 gaatccccag ctttcaccgt ctagattcat tcgaataatc cggtgattgg tgcgggctgg
     6241 atagttcaag cgacctctat atccttcgtt ttccatgcaa agcatgcagg taggatagtc
     6301 tacttttacc gcctcgcgtt ctgctgcgat ttgttttgga tctttttctg gcttagataa
     6361 attgattgtg atttccagtt caccatactc cgactctgcc ggaaatttga tgttttttgc
     6421 gatggctctt gttttgatgt agtcattttt cttacttaaa ttaaagaaat actcagttgc
     6481 ttcctctggg cttttcgaat agtgctgtgc aaagaatgca ttgacgactg aaggtggcgg
     6541 tgtgagaaaa tccattaatt gcgcttcaaa aatctcttgt tctgctggca attctgaaag
     6601 aacaccattt tctcttgcct tagcgacaag ctgatccaat aagtctacag attcttcctt
     6661 aactggtctt acttcaatgc tttctagagc atcttctcct accatcccta aaagacgatt
     6721 ctgtaaatat aagcggtcca tttccatcca tccgccagct tcgatcgcaa gtgtggcaaa
     6781 atcacaaatc gtttgactga ttgacatatc tcattcccct attcttcata accatttgga
     6841 tggctgacat gccaatccca tgctgttttg ataatcgctt tgatatctgt gtattcaggt
     6901 ttccagccca gaatctctct cgctttttca cttgaagcga ctaatcggct aggatctcca
     6961 gctcttcttg gtgctatttc tgctggaatt tcttttcctg tcacttctct agctgcttct
     7021 agcatttcct tgactgagta tcctttgctg ctgcctaaat tgaagaagtt gctttcattt
     7081 ccttctttca agtattccaa agctaaaata tgtgcagcaa tcaaatcttc tacttgaaca
     7141 taatctctga tacatgttcc atctggtgta tcataatcgt ctccataaac agccaaggct
     7201 tttctttgac caagagctac ttgtaaaatg attgggacaa gatgcgtttc tggtgtatga
     7261 tcttctccga tagatgcatc tgcttttgct ccggctacat tgaagtagcg caaagcgaca
     7321 tagcgcatgc catatgcttg gtcacaccac ttcatcattt tttccatcat caatttactt
     7381 tcaccatacg gatttttagg attagctggt gtatcttctg tgattggaga ctctttcggc
     7441 tctccataag ttgctgcagt agaagagaat acgattttat tcacgttgaa ctcgtgcatg
     7501 acttcaagta agatttgcat accgtatacg ttgttgttga aatacatcaa tggtttttcg
     7561 acagattctc ctactaaaga gcttgcagca aaatggatta ctccttcaat cggttccttt
     7621 tcaaatacgg aacgtagaaa ttctttatcc cggatgtctc cttcataaaa atgagcatct
     7681 ggatgtactg cttgtttgtg acctgtgagc aaattatcta ccacagctac ttgatacccc
     7741 ttttgaacta gctggtctac agcgtgcgaa ccgatataac cggctccgcc tagtactaaa
     7801 attgtcataa aaaacactcc tttgattagt aaaattgtgt ttgttgattc tatataattt
     7861 aaaaaacgaa gtttactttt atggtgaaaa caaacaaagt aaaatttcgt aaattcatat
     7921 ggtaaattta taataaaaca tttagtaaac attttcaagg gttttttgca aaggtttaca
     7981 aacaaacgta aaactagcct ttttttctct tttgttccat aatagatata acaaataata
     8041 aatgaggtgg attcaatgaa aaaatttgta tctggaatat tagtaggaag tctggcaaca
     8101 gccgctgccg ttgctggttt ggttgcttct gtgaaaaaaa cagtgatcga tccaattgac
     8161 gaaaaagaag caatgatcga agaaaaccgt aaaaaagcaa tgcgtaaacg cgtttctcgt
     8221 taataattat ttaaaaatac gcatgaagac tttctaaaaa acagataagt catcatgcgt
     8281 atttttattt gtcagtcaat ataagttgtg ctattttatc tgcctgtctc agattccatg
     8341 gatctgtata aggtctagct actgctgcag ttagccaatc cacaccttca acaggtattc
     8401 catagcaata aaagtcagac tggatttccc ctgaagcatc aatcacgcga ttcgtacctc
     8461 gctcaacatc tatagcttct gaatgataac ttcctgtatt atctgaaaat gaaaaagggc
     8521 gaacaagttt gttttccttc aaatttttta tgacaggatt acttgaacga gaaaagcttg
     8581 tttgtggcaa tcgagcttca atcaaatagc gactgctgat ttctttatct tgtagagaaa
     8641 taacatagcg gttgtgcttt tgctgaatat caaatggcgg ttcgatcaaa tgaaaaatac
     8701 ccgcatctat cagtgctgct aattctttcg tccgaatgat tggcggaccg atcgttaaaa
     8761 agctatttag atgagtaaac catccccata gtatttcttt gtattcctta gcagaaaaaa
     8821 cgtgccattc aatagcctgc cggattggat cacgccagtc ttttaatgca tcaaatgttg
     8881 aagcaaatgc tcctgtgcaa ttgccttttt ccgcttcttt tatctgccct tcaataaata
     8941 ttcggctagc ttctgaaaag ggctcattct gataggcaag aggagtttct aaatacgacc
     9001 aatcccatct ataagggatt agtgctggat gctttccgag acactcctct gaagagaggg
     9061 agagaaaatc atgctcaaaa tttttctttg gaatcggcaa gtgatattct tcgatgattt
     9121 tcttgtaata aaacaactca acgtcttttt tcagatagtc aaaaaatgtt tcgccagtca
     9181 aaaatcccga ctgatgccat tgctccaggt tttcttttgt tagtaaccgt ggccatgcca
     9241 ttgctccgcc ttgcttttga tttcttcctc gagggtaata agggagcccc cttcttgatc
     9301 cactgtatac aatcggttcc ttgcctgatg gatgatagac cagttttccc ttttcgttct
     9361 cgaagcgccc tcctcttgat actgtaaaca atccgacata atcaaaaaaa cttaagccta
     9421 gacctcttaa aaagacattt tctttaggcg gtatcttcga aagatctaca tctgcaggat
     9481 tagaaggaag ctgatacagt aaaacatttt tctttgcgta gtctacccac actctttctt
     9541 cttctgtctc atcattttcc cagtgaccgc ttgctaaaac aagctgatcg atagaatagc
     9601 tttgctgatc tgtctgtaaa agataaccat cttttctttt gcttactttt tttactaaag
     9661 aataaacaaa ctgaatagaa gctggaaatt cttcttgcaa ctttgagaaa aaccagcgtt
     9721 gatagagtcc gtataaacat cgagtagatt gctgatcttt ttccagacga ttgatttctt
     9781 ctataattag ttgcttattt ttggttaccg tctgttcgat ataatctgta gcaggtcctt
     9841 tactccattg aaacaagttg ggtccctgtg ttaccaatcc tccactggac aatgtttcat
     9901 ctgtaaaaag cgtcacttgt tgagaaacag aattcattaa taactccggt ggctgattca
     9961 accgccaaac tcgacctcca ggaccattgg gatcgaaaag aaaaagttca agagaatgtc
    10021 tgtcctgatt attatggaga atcctttctg ctacacttaa tcctctaggt ccggcaccaa
    10081 tgatccctat tttcatttgc atgcctccat ttcgataaat tttttcaata aaacagcatg
    10141 gttctgatgt tcattttttg caccataaac aaaagtaatg actggatgtt ctttcataag
    10201 ttgactgagt ttaaaaatag cttgcttctt ttcttcttcg aaaatcaatt cttgctggta
    10261 tttctttgca aatgaagcaa atcgttctgg tacatggtca aaagttttgc gtgcttcatt
    10321 actaggtgca atttctttca accacagatc taactgcgct ttttcttttg aaattcctcg
    10381 tggccagaat ctatccacga gtattctata gccatcctct ttttcagcat caaggtaaac
    10441 acgttttaat ttgatcatag ttgtttcctt ctttctacct tttcgcttag cttatatatg
    10501 tagataatag cacaaaataa aaaaaatgaa cggcacaact atccattgcg ccgttcatgt
    10561 gatcttggtc aaaatctaat gattgattcg gtttttaaag ctgtcataca atcatctgtt
    10621 ttatactttt ttacttttga tttttccaga ccatccgtca tatccaccct taagtaaata
    10681 aatctcttga taacctgctt tacgtaattt atttgctgta cggatgctca aacttttctt
    10741 ttgatcgtaa atatagacag gctggtcttt tcgaatagat cctaatgaat ctttcaaaac
    10801 agtgtaaggg atgtttcttg cacctaaaat atgcccagca tcaaacacat ctttttcgcg
    10861 aacatcgatt acttgtgctt ttctcattcc ttctcgaaat tcttcttctg tcaaagtcgt
    10921 tgctgaacgt ttggccatta ctcgtagata gacttcccaa aggatgattg caagcacaat
    10981 caatagcaaa atgatattaa ttacccataa aaccatgtaa tgcctccgtt tttttaagca
    11041 aatttcaagg ctaatgaggc agcaccaatg acaccagctt cattaccaag ctctgctaat
    11101 ttgatttttg ttgattctct tacttgcggg aaagtaaatt ctttaaaata tttctctaca
    11161 cggctacgta aaaattctcc tgctgccgat actcctccac ctaacacgat acttgacgga
    11221 tttaatgtat tccccaagtt tccgcaagct aaacctaagt agaagcatac gcgatcaaca
    11281 accatcaatg caaacggatc gtcttcttga gccatttcaa agatatcttt acttgttact
    11341 tcttctccgt tgtctagcat tgctttcagt tttgaatccc ctgcgtattc ttctgccaag
    11401 aaacgaccta ggcgtaccac acctgtagcg ctagatacag tttctaaaca tccgcgttta
    11461 ccgcaagtac attcgaaccc ttcaggatcc acagtgatat gtccgatttc tcctccagct
    11521 ccgctcacgc cgtgaatcaa atttccgcca gcaacgatac ctccgccaac acctgttcct
    11581 agagtaacga atacaacgtc tggatcgttt tctccagcac ctttccatcg ttcacctaaa
    11641 gcagcaacat tcgcgtcatt atcgatagcg aatttgattc ctgttcctgc ctcgatcagt
    11701 tttttcacaa attgaacttc tgtccagttt aagttatacg caccaataac cgttccagct
    11761 tcgctgtcca cgcttcctgg ggtacccatg ccgattccga taaagtcttc ggctttcata
    11821 ttatataaat tcaaacgatg attgattgat tcaatgattt caggaacgat atgcttacca
    11881 tcatccaaaa tattggtatc gatgctccat ttttgctgaa tctctccttc tggtgttaaa
    11941 attgcaaatt ttgctgttgt tccacctaaa tcaatcccaa taatcttctt gtccattaca
    12001 aatttccttt ctttcggctt tcttcaattc ggtgctctct ttttaatatg cgccacgctg
    12061 tcatgtatgt atcatgatca atcaaacggc tatcatacag attacgcaat tcgatagtca
    12121 ttaattcaat gtcatagatg cgtgcaccca catagataaa gatgccaaat tttttgaaca
    12181 gctgctgtac atcatataag ctctccatct ttaagcactt ccttcatatt atacaagtaa
    12241 accatatttt tttaaaccca gtaaaataca tattacaaaa agaaatacaa aaactagtgt
    12301 agaaagaatc ctttggtgta tcgaatagct tgtctgttgt ttcggtagac ccaaaacatt
    12361 ccctaacact aatccgccaa ttagcccacc gacatgtccc caaacatcta cagaggtatc
    12421 cagaagacca aaaacaaatg tcaacacaat aaataaaaga aaatgtctga ctagctgctg
    12481 gatcgctggg ttatgtttaa aatgaaaccc taagataaac aacgcaccga acaaaccgaa
    12541 tatcgaagta cttgcaccac cagacagaac attcgcttcg ttaaaagcaa agcttgctgt
    12601 atttcccatt atcccgctga acatataaat caagaaaaaa cgccaatggc catagattgc
    12661 ctcgatttgc tgccccataa aatacagtat cagtgagttc attacgaaat gcatcagtcc
    12721 aaaatggatg aagattggtg tcactaaacg ccaccattca ttgaagtgaa caagataagg
    12781 accatacatt ccggcataat aagggatctc aagtcgcgga aataattcca tcatgaggaa
    12841 gaccgctgtc tgtatcccta aaaaagcata ggtccataac ggtcgtctta accatgcacg
    12901 caattttatt tgctgttgat aattcatgaa aacctcccat ttcattttag tcaataaaca
    12961 attgttggat cttctgatca aagctctccg gttgccattg ttcattcaat tgttcacgaa
    13021 aaacaaggct acatgttttt ttatgaaaat tatttaaata ccggtcgtaa taaccaccgc
    13081 caaaaccgat tcgataaccg gctctattgt agataatacc tggtacaatg aggagatcga
    13141 tcatctccgg caaatagagc ttctctgatt gtggctcaag aacaccaaaa ctcgaacgta
    13201 caagaacgga ctgttcatcc atttcataaa acgccatctg acgtttcggc aaagttttag
    13261 gtacaactat tttcttttgt tctttttctg ctcgttggat aaccggctgt gtatccagtt
    13321 caaattcatt cgataaagtc gtccctatca cttttgctga cttccagtac tcgctggcga
    13381 atagctgttt atagattcgc tgttcttttt cctttttctt gccacttttg gccagatttt
    13441 tcagcttttc gattcctttc cggcgtaatc ttactttcaa ttggtccaaa aactcaccct
    13501 tccttctctc ataaaatggt ataggaaaaa aagaaaaata gcaatcgaac tttcaaataa
    13561 atgcataaat agaataaaaa gaagacctag aaatgattgg ccttcctttt ttaatgaatt
    13621 tcaactgttc agcgcgtgtt tttgtctgat aaaaagtgca tacagaaaat atggcgcacc
    13681 aaaaagggca atcaaaattc ctgtaggtac ttccccactt ggtagaatca ctctagcaac
    13741 catatctgca ctaagcagaa aaatggaacc gaacaaaccg ctcagaacaa aggtccagtt
    13801 attttcttta cgtacgacta gcttcgcagc atgaggagct agtagtccta caaaagataa
    13861 actacctgtc accgctacac taccgcttgc caaagcaaca gctaacaaca aaaggatttt
    13921 ttgactttta gccacgttaa ggcctaatcc ttgcgcgcgt tcttgaccaa atgatagcaa
    13981 tacaatcctc tgtgcataaa gtcctcctag cggaattaag ataaccgccc atggaagcaa
    14041 tgcccaaaca taaggccagc tcgcacccca gattgatccc gctaaccatg cattcacaaa
    14101 tccataattt tccttagata attggatcgt gcatagcaat gttaatgcag aaaggccggc
    14161 attaacggca ataccggaca ataagattcg attcataccc aaaaagccat ttcgatcata
    14221 ggccgcaaga tagacacagc aagcagctaa aacaccacct agaaaggcta caactagcaa
    14281 tagaaacggc agcgaatagt gcgaaaagaa acctaaataa agcatcacta aaaatcctgc
    14341 tccggcatta atgcccaata tactagaatc tgccaattca tttcttgtta ctccttgcaa
    14401 gatataacca gaaacgccaa gacaagctcc tgctaataaa ctgatcagta atcgaggaac
    14461 tcgaaattct ctaacaatca gcgccaaaga agatgattct ttccctatga acgtggcaaa
    14521 aagctgatcc aggtaaataa aaggcgtacc aatcattaaa ctacctatag acaggatgac
    14581 aagtacaaaa agcaagaaat agaacgtcca atatattttt ttcaccgttg ttccctcctt
    14641 acttgtatca gtaaaaacgg aacgccaatc aatgcaatga ctaatccaaa aggtgtttca
    14701 aaagggggat tgatcatcct cgctgtaaaa tccgccaaca taaccaatcc accgccaact
    14761 aaaaaagaga caggtagaac ataacgatag tccgttccaa ccattccgcg aacaactggc
    14821 ggaaccaaca gcccaataaa tgaaacaggt ccgactaacg aaacggcaat ggctgctaac
    14881 actgcaacta gacagaaaac aatcaaccgc gttcgtttag gatgacttcc aagagctaat
    14941 gcatgtgttt cactcaaatg aatcaaagat attgcttttc ctaatgaaaa agaaaccaaa
    15001 acagcaagta tatataaagg aaacaatact gctaattgtt tccatgtgat attggcagct
    15061 ccgcctacaa accaaaaagc aagatcctgc tgcagattaa agaattgggt aagtgcttgg
    15121 ctgatagcag taaaaaaaga actaatagct acgccagcta aaatcagctg taaaggattc
    15181 atgcccattt tcgaaaactg caaaaaacca aatacgagca aagttacagc aaaagaacct
    15241 gccaatgaca ttagaaacac agaaaaatca gaagctttag gccaaaaagc aaaactaagg
    15301 gccattgcca acgaagcacc cgcgttgatt cctagtaagc ctgaatctgc taaaggattt
    15361 cttgtcactc cttgcatcaa tgcaccgctc aatgcaaaac aactccctac aagaaatgct
    15421 cccgccacac gaggcaaacg aatatttcgt atgatttggt gactttgttt tgatctatca
    15481 aaatcaaaca acgcctgcca aaaatctgct ttttccacag tcgctgcgcc atttgaaaga
    15541 gcaacaaaaa aaataatcaa aagaacaaaa cagaccaaaa gcaggagtct atttttcttc
    15601 atagtcctca taattgatcc tcctgctctt ttggcaacaa atcataggtt agaaaaactg
    15661 gtttatttgt tcttggaagc gtgacaatcg ttgcatcaat ctcaaatatt tttttcatac
    15721 actcttttgt gatcacttct tcaggtgtac cttctgtgat caacttaccg tttttcattg
    15781 ctaataaata atctgaaaaa cgtgaagcat gattaatgtc atgaatcgac atcaagatcg
    15841 ttgtttgttt catttgattg atttcagtca ataactgtag gatctctaat tggtgtgccg
    15901 gatctaaaaa tgttgtcggt tcatccaaga tcaagatatc tgtttcctga gcaagcgcca
    15961 tagcgatcca gacacgctgg gtttgtccac cagacagcgt tgcgatatcc cgcatacgaa
    16021 atccagctag acctgtagca tccaacgccc actcaattgc ttcatgatct tgcgtgtcca
    16081 tgccactgaa cagtttttga taagggtatc gtccgtaaga tactacttct tctactgtca
    16141 tacctgtagg gtgttcacta gtttgtgcta ataatgcaat tttttttgca agttcttttg
    16201 aactgtatgt agagatatca gagttattga caatgatctt tcctgatttc acaggtagta
    16261 tacgggtaaa acttttcaat aaagtagatt ttccacttcc atttggccca atcaaactag
    16321 tgattttccc ttcaggaatc gtaacagaca tgttttcaat gatttttttg ttttcgtagc
    16381 cggctgcaat gtcagctgct cttaatctcg tcatttcacc catcctttcg ctgaaaatca
    16441 ttctcaatta tgacgctgtt tcaacatttc gtcaagcgct actttcatat ctatagccaa
    16501 atgaagcggt tgacagcgtt cgaaatatca ggaataataa ccaatgagaa agattctcaa
    16561 ttatgttagg aggaaagaaa tgaaattaaa aacaaaagta ttcacattat ctagcatatt
    16621 gctgctggct ggagtactga gcgcttgctc cccctcttca gataaagaaa cagctacaac
    16681 tgccaattcg acgacttcat ccaatagtac tcatacagtc acagatacac ttggacataa
    16741 agtagagatt ccaaacgcgc ccaaacggat catcggcagt tacttagaag actatctgat
    16801 tgcactaggg gaaaaaccta tcgcccagtg gactgttggc agtggttcca ttcaagatta
    16861 tctgcaagat gatttaaagg atgtcccaac gatttcttat gaccttcctt atgagaaagt
    16921 gttaagcttt gagcctgatt tgctgttgat ttcttcttcc gctactgtcg aaggcgggaa
    16981 atacgaacaa tatagcaaaa tcgcgccaac ttatgttgta aaaaacggaa cagatgtcac
    17041 atgggaagaa caactaaaag atgtcggcaa agctttggca aaagaaaaag aggcagaaaa
    17101 aatcatttcc gattatcaaa aatccatcaa gaaaactcga gaagaactag cagataaaat
    17161 cgagaacaag acagctgcag tgttgtgggt gaccaacaac tcagccttta tggtcagcaa
    17221 aaatcggtca agtggaagaa tcgtatacga cgatctggaa tttggtgttc ctgatctagt
    17281 ggaagaggtc tccaaaaaag ccacttctga ctggtctgct gtttcctctg aaaagctagc
    17341 tgaattagat gctgactaca tcatccttgt gaacagtgac aaagatgctg ccatgttcaa
    17401 tgaaccaagc tggaagaatc taaaagcagt gacagacaat catgtactgc aattcggacc
    17461 tgaatctagt tggctatata acggacctat tgccagtcag gaaatggtca atgatatcaa
    17521 agaaaaacta aattgatttt aactaaaaaa agcatcttca cgattagtcg tgagatgctt
    17581 tttttcttat taacaaacta gacgcataga ttttattctt cttttgaagc aaccctattt
    17641 tttactcttt cccatttttg aaaacgatgg gcatatagat tttcttgatc cgttatcccc
    17701 tcatactcct ctataagggc gaagtctgaa aaatcaatat tcccaatata cgtatcgcct
    17761 tcaaacgtgc tatcgatcaa tgttcgccag atccgaccag tgtaaggaag aagttcttga
    17821 aaaatccgac taccacccga aacatagata tcttctgaga tcgtttgact atacgacaaa
    17881 agttcatcga tcgaatgcat tacttccgca ttttctttcg tgcgaaaatt tggttgcgtt
    17941 gtcaacacga tgatatggcg ataaggaagt gaaagatccc ccattccttc ataggtcttt
    18001 cttcccatca ctaaaattcg atccattgta tgttcgcgaa agaaacgcat atcatttggc
    18061 aatcgccatg gtaacaaacc atttttgccg atcagaccat ttttatcttg tgcccacatg
    18121 gaaataaaca tattatccgc tccttatgat tttagatgtt ttgagataaa aaaagtctca
    18181 attctttgac cagcaaggaa ttgagaactt taaaaacatt attttgtttc acggtgcaaa
    18241 gtaactttgc gttcgcgtgg gcaatatttt tgtttttcca aacgatcagg attgttacgt
    18301 ttgtttttgc ttgttagata gttacgttct ttacaagaag tacactctaa agtgatgttt
    18361 acgcgcatgt ttttccctcc catttttaca agaatcctct aagatgactc tcagacttga
    18421 ttatcttacc atgatttttt ctagattgct agtgtttttc acgattttgt taagtaaaac
    18481 tacttgacga taaatacaac ggttttactt ctcaaacaaa atctttttct ttttgtataa
    18541 atacccttac acttgtttat atagattatg ttttttaata aagggggata ctaatatgcc
    18601 atggaacatg aaggactttc ctgcatcaat gaaaaactta gataaattga caagaaaaaa
    18661 agcaatcgac atcgcaaatg cattattaga tgaagggtac cctgataacc gtgcgatccc
    18721 aattgccatt gatcaagcaa aaaaatggta tgaagatgct agtgaatcag aaaaacgaac
    18781 tttcgaaaaa gaaaaaaatc caagcaagac ggatgaacac gatacgaatc ctcgtgctgg
    18841 aaaactgctt gattcagatg tgatcgtaga atatgaggaa gaacaatgga tcgtgaaatc
    18901 taaaggggca aaaaaggcaa gcaaccattt tgatacaaaa aaagaagcaa tcgaaaaagg
    18961 aaagcaagta gcacaaaaca aagaatcaac tttgttcatt tataaaaaag atgggacaaa
    19021 agaaaaagaa atcgattatt gaacatatgt aaaggggttg tgacgaaaat cgtgtcacaa
    19081 cccccttatg ttcgaaacaa tggtgttcct ctgccaactc cgaaccataa gtcataatat
    19141 ctataaaacg ggaagagctg ttttttgaaa ttgtttctta tcactcagtg ttaaacggta
    19201 ggagaaaacc tcttttttat tgatatttga ttttcatcaa acagtcacat agtcgattgc
    19261 ttctgcttgc ggaatcgttt catctacaaa gtagacttta taccatgtca agaaactgaa
    19321 gattgtccag atttttcttt gctcttcttt acgtccttcg tgatggtcat ctagcaactt
    19381 catgattttt tcttgatcaa aaaattcttt tgcaaaatct gcttcgaata atgctttgac
    19441 ttgttcgtag ccgtgttctt ctttcaacca agctttgatt ggcacaggga atcctaattt
    19501 cacacgattc gaccattctt ccggaagatg tttgttcgca gcttgtctga aaatatcttt
    19561 tgtgttgttt tgattcaata aaaacttact tggtatttgt tgagccaatt tcatgacttc
    19621 gatatccaat aaaggtactc ggacttccaa agaacttgcc atagaaagtt tatctgcctt
    19681 taacaagata tcttttggca tccattgatg aagatcgaca tattgcatct tattgacttc
    19741 atctttgatt ccttctgttt tctcgtaatg aacagtcatg atttcatcca cagatggtgc
    19801 tgtttgatat tttggtgtta acacttctga tgcttctgat tcttcgaaca ctcgagcatg
    19861 accgataaaa tattcttttg caggagcaag tgattcatat aaatggatcc gtccatggaa
    19921 gtttttcatt tttccgattt tacgtcctaa attatagcgt gttccttttg gtaatttttt
    19981 caatccttga gcaatcacac ggatgaattt tgaattcgta tggaatccat acgtttggta
    20041 tcccgcaaac agttcatccg ccccttctcc agattggact acccgcacac tttgtgaagc
    20101 aagatttgct aaaaagtaca aaggtacgca agaaggattt gaatcaggtt catctaagtg
    20161 atactggatc aaagggaatg ctttgaacga catgtctccg tcgatcactg ctgctgtatt
    20221 atctaagtcc aatagttcgg ttagttttct ggcttcaatc gcttcattat aggttttatc
    20281 atcaaacccg attgagaaag aatgatctgg tttcaataca gaggttacat aactggaatc
    20341 aaccccgctg gataagaaag aaccaacttc tacatcactg accgtatgtg cttcaataga
    20401 agcttgaacg gtttcgtcga ttttttcgat ccattcttgt cgggaatgcg tttcttttgt
    20461 ttcaaaatct gcatcccaat attgctgaat gtctattttt ccatctttat acgtataata
    20521 atggccttca ggcaaacgat agacatcttt gaagaatgtt tcgccgttta atggagaata
    20581 ttggaaagtc atataaggtt tcaacgcttc tttgttcaat tctttgttaa aatcaggatg
    20641 aggcagaaaa cttttgattt ctgaaccaaa cataaatgtt ccgttcattt ctgcataata
    20701 atatggtttg atcccaaagt ggtctcttgc accgaataac tcattctttt cattatccca
    20761 aatagcaaaa gcaaacattc cgcggatctt ttgcaataat tctgttcccc attcttcgta
    20821 accatgcaaa aggacttctg tatctgcatg tgtttgaaaa acgtggccag ctgcaatcaa
    20881 ttcttctctc aaaggctggt aattatagat ttcgccatta aaaataatga tctttgtccg
    20941 atcttcattg taaataggct gagtaccgcc ctctaagtca ataatactta atcttctgaa
    21001 tcctaaagca acatgtttat cgatatattc tcctgaacta ttaggtccac ggtgaacgat
    21061 tcgatccatc attgtattaa taattgtttt tttgttgtcc ttgtcgttaa caaaacctac
    21121 aataccgcac atttaacttt cacatcctaa tataaaatta ctgtttattt cattcatatg
    21181 catcttatca tagaataaat agcggacgaa tattttctct cttacaattt cgtcacgtga
    21241 aaacaaaaga tgaaagtttc tgtttttaca gaaaataaag tcccaatatc taatttacca
    21301 tgttttcttt tttgaggcta ccttattctc ttcgtgttaa aaaaatatta gtggatgcta
    21361 tttccaaaaa aaccagcaaa aaaagacacg acctaaagat cgtgtc
//
LOCUS       DACCVZ010000046        20617 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.046, whole genome shotgun sequence.
ACCESSION   DACCVZ010000046 DACCVZ010000000
VERSION     DACCVZ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.046"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..115)
                     /locus_tag="IVW63_001728"
     CDS             complement(<1..115)
                     /locus_tag="IVW63_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP7860006.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="IVW63_001729"
     CDS             246..698
                     /locus_tag="IVW63_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860007.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="IVW63_001730"
     CDS             712..1401
                     /locus_tag="IVW63_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860008.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..3877
                     /locus_tag="IVW63_001731"
     CDS             1526..3877
                     /locus_tag="IVW63_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HAP7860009.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3957..4352
                     /locus_tag="IVW63_001732"
     CDS             3957..4352
                     /locus_tag="IVW63_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860010.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4677..5294
                     /locus_tag="IVW63_001733"
     CDS             4677..5294
                     /locus_tag="IVW63_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7860011.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5335..5634
                     /locus_tag="IVW63_001734"
     CDS             5335..5634
                     /locus_tag="IVW63_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860012.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5668..5835
                     /locus_tag="IVW63_001735"
     CDS             5668..5835
                     /locus_tag="IVW63_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7860013.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            5856..6197
                     /locus_tag="IVW63_001736"
                     /pseudo
     CDS             5856..6197
                     /locus_tag="IVW63_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(6277..7569)
                     /locus_tag="IVW63_001737"
     CDS             complement(6277..7569)
                     /locus_tag="IVW63_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP7860014.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSECRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
     gene            7636..7947
                     /locus_tag="IVW63_001738"
     CDS             7636..7947
                     /locus_tag="IVW63_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7860015.1"
                     /translation="MFWKIKKMLVSSTNIKKYRAKKIKERQAQGIEIAKKKGKFKGRQ
                     HKFKENDPRLKHAFDLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRD
                     S"
     gene            7947..10091
                     /gene="topB"
                     /locus_tag="IVW63_001739"
     CDS             7947..10091
                     /gene="topB"
                     /locus_tag="IVW63_001739"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP7860016.1"
                     /translation="MSTVILAEKPSQALAYASALKQSTKKDGYFEIKDPLFTDETFIT
                     FGFGHLVELAEPGHYDEKWQNWKLESLPIFPDRYDFEVAKDKGKQFKIVAELLKKANT
                     IIVATDSDREGENIAWSIIHKANAFSKDKTFKRLWINSLEKDVIRSGFQNLQPGMNYY
                     PFYQEAQTRQIADWLIGMNASPLYTLNLQQKGVQGTFSLGRVQTPTLYLIFQRQEAIE
                     NFKKEPFFEVEASIKVNQGSFKGVLSPTQRFKTQEELLAFVSSKQAKIGNQEGIIADV
                     QTKEKKTNSPSLFSLSSLQSKVNQLYKATASQTLKAMQGLYEAKLLSYPRTDTPFITE
                     NEFAYLKANFGKYSGFLGLDLEMVQTEPRKRYVDGSKVQEHHAIIPTKQVPTESALAK
                     MDDLQRKIYALVVKTTVAMFLPDYLYEETKIQTKVADLLFQSIGKTPKQEGWKILFKQ
                     QTKEEKEDVQTLPLVIIGERAEVGVKSVEKETQPPKAFTEGTLLTAMKTANKTVDDEE
                     AIKILQEVEGIGTEATRASIIEALKQKEYIQVIKNKLVVTEKGKLLCQAVESQHLLTS
                     AEMTAKWETYLKKIGKREGNQENFITNIKKFIVHLLEAVPNDIEKLNFSDYQEQKEKE
                     AEKSIVGKCPKCGNNIVLKKSFYGCSNYPECKFTLAEHFRKKKLTKTNVKELLEGKET
                     LVKGIKNKEKKPYNAVVKIGEKGYIDFISFSK"
     gene            10211..10450
                     /locus_tag="IVW63_001740"
     CDS             10211..10450
                     /locus_tag="IVW63_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013646120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAP7860017.1"
                     /translation="MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMEIRLRSKLKSVLIVHYLKILYNRN"
     gene            10499..10583
                     /locus_tag="IVW63_001741"
                     /pseudo
     CDS             10499..10583
                     /locus_tag="IVW63_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
     gene            10708..11445
                     /gene="erm(B)"
                     /locus_tag="IVW63_001742"
     CDS             10708..11445
                     /gene="erm(B)"
                     /locus_tag="IVW63_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAP7860018.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(11642..14608)
                     /locus_tag="IVW63_001743"
     CDS             complement(11642..14608)
                     /locus_tag="IVW63_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HAP7860019.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            14754..15329
                     /locus_tag="IVW63_001744"
     CDS             14754..15329
                     /locus_tag="IVW63_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016204422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7860020.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            15543..16238
                     /gene="vanR"
                     /locus_tag="IVW63_001745"
     CDS             15543..16238
                     /gene="vanR"
                     /locus_tag="IVW63_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAP7860021.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            16216..17370
                     /locus_tag="IVW63_001746"
     CDS             16216..17370
                     /locus_tag="IVW63_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAP7860022.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            17585..18553
                     /locus_tag="IVW63_001747"
     CDS             17585..18553
                     /locus_tag="IVW63_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAP7860023.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            18546..19577
                     /gene="vanA"
                     /locus_tag="IVW63_001748"
     CDS             18546..19577
                     /gene="vanA"
                     /locus_tag="IVW63_001748"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAP7860024.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAFITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            19583..20191
                     /locus_tag="IVW63_001749"
     CDS             19583..20191
                     /locus_tag="IVW63_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAP7860025.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         6874 a         3420 c         4172 g         6151 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattatgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt
     3781 tacttatctt gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat
     3841 tattcaattt caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt
     3901 gtccttttcc tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga
     3961 tgattatgga agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat
     4021 gtggaattat ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca
     4081 agatagtaga ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt
     4141 ttgaaagagt accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag
     4201 agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc aagcgacttc aaagaaaaaa
     4261 agaaagaata caattatatt gtaaaggcaa aagtatcaaa aagatttatt tttaacccta
     4321 aattagaaat atatagtgtt gtaatagaat aatagtgtta aaaaaattgt aaaagttaaa
     4381 gaagtcaaat tctgatgtga aaaataaaat ataccatgga agacataaaa gaaaaactgg
     4441 ataactagtt tatttaatgg cagaccgtta aggcctgcca tttttatgta ttttagcgga
     4501 ataaatataa tcatgcggga gtgtaaactt actgtttcaa aaagtatact ttttgacatg
     4561 ccttgatttt ctttgtttat gtatggcata ataaccacat aatacaattt gaaacgtttc
     4621 tgatttaatc tgattgtttt gaaacaattt tagtgaaaaa agggtagata aaaacgatga
     4681 gaaaattttt ttatatccgg gtcagtagtt atgatcaatc gatcgaacga caactgattt
     4741 ccgcgaagga attaggaatc cctgaagaat atatatttgt agaaaaagcc agcggcaaag
     4801 attttaaacg ccctgaatat caattaatga aacggatgtt tcgaaaagga gatttactct
     4861 atctacaatc attagataga ctaggcagaa ataaacaaat gattttagaa gaatggcgag
     4921 aattaactaa ggaaaagcag attgatattt ctgtgttaga catgcctctg ttagatactg
     4981 ctagttacaa gcaactagat gggttagaga cgcttatctc tgacttaatt ctgcaattac
     5041 tcagctatat ggccgaagac gagcggaaac gaattaatag ccggcaaaga gaaggcgtag
     5101 aagctgcgaa acaaaagggt gtaaaattcg gcagaaagaa aattgcttta cctcctgaat
     5161 ttcctgcgat ctattctgac tggaaagcag gaaagataac tgcagtctat gctatggatc
     5221 aattgggcat gaaacgaaat accttttatc gacgggtgaa agaatatgaa cataccttgc
     5281 accacttttc ttgatagata taacagctat tagacgggaa gggagagttt gaaaatggac
     5341 ttaacgaatc aaagggtcgt ttttactgga acgctgcagc aaatgacacg aacccaagcc
     5401 atcggtttgg ttcactcttt aaacggccat tgtcaatcaa gtgttacttc aaaaacaaat
     5461 ttcctggttt gtggtcagta ttctaagtcg ttgtttgatg attctctcta tacaaaaaag
     5521 gaacaaaccg cgcgggactt gattgcgtta ggtcatgaga ttaccatttt atcagaagtc
     5581 gaattttatg cgttaattag tcaacagttg aaagaatggc aacggtattt ataatcgtta
     5641 gtaaaattta caaggaggaa aatttttatg aagcgaaaat cttatgatcg ttggggcatt
     5701 gaaataacta gttttaatcg aaatattgct tttcacgtgg agtgtgactg tggggaatta
     5761 gcaaaaagtg tttatcaaaa aaattacttt tactgtccta aatgccatcg ccgatacggg
     5821 gtacatggaa catagaaacg aaatagtgcg gtagaaaaga acagaactta gatcggcaat
     5881 tacaagcgtt acagggcgtt tctaaggtct tttcagacaa attaagcggt caatcggtcg
     5941 aacgcccaca attacaagct atgcttaact atattcgtga aggggatatt gttattgtta
     6001 ctgaattaga tcgattagga cgaaataata aagaattaac agaattgatg aatcaaattc
     6061 aaattaaggg ggcaaccctg gaagtcttaa atttaccctc aatgaatggt attgaagatg
     6121 aaaatttaag gcgtttgatt aatagccttg tcattgaatt gtacaagtat caagcagaat
     6181 cagaacgaaa aaaaatggct ctttgtcaaa tgatgttggt aaagagaaat cttagaataa
     6241 ttggagatca agtggatcag ttcctcttga tcttttttag ttgaaaatca atgcgttgcc
     6301 atgacgaatc atgatgcgca atttgaaatt ataaaagcta cgaaagccat atgcatttcg
     6361 ttttaacact ttgatatggt tgttcagaca ttcaagtggg ccatttgaat aactttgttg
     6421 taaagcattt ttgatttgtg gcagaaattt ctggaacgtt ctcaaggtcg tctgatagcc
     6481 ttcgggaagc atgatattat tggtaagtag ttcttcaaac gatacgtagt ctcgttcctt
     6541 tacagcgtaa agaaagtctt gatataactg atagcctaca cgcaaagcag ggctcccttt
     6601 cagtaagcga tccacaatat cggtctctgt taaatgagct ttgaagccag gtcgccaaag
     6661 gcgtcgagta taatcaagct tgcgttcatc tttttgaaga agtttccagt atctttttaa
     6721 ttgcttacct aattgatagt gtttttgttc tttgcttttt aatagttggt tcgtttcttt
     6781 gattcgatga ttgcgaaagg tacgaccaat atgttggacg atgtgaaacc ggtcaataat
     6841 cagctgtgct tttggaaaca gctttttaac gagcgataca taaggagcgt acatatcaat
     6901 cacgatccat tcgaccgctt cacgaatttc tcgtgaaaaa tgactaaaat aacgttttaa
     6961 aaaaggcagt tgtcggttct cgacaatgtc caacaagcgc tgtgtttgtc catccatcat
     7021 gatgaaactc atagcacctg aaacaccccg aactgatttg aattcatcaa aacaaagtac
     7081 cttaggtaac ggtgtccgaa aaggattcaa cggacgataa aatcgcttca taatacggta
     7141 aacagaagag accgatagat ttttctgagc ggcgatctct gtcattgagg tatttttttt
     7201 cagacgagtc acgacagacc agcggacttt ctcactgatg aaacagtgtt ttttcgcaac
     7261 agaagtatct gcgacaaagg tccgctgaca agctttgcat ttgaagcgtt gctttttcaa
     7321 ttcgaggtag gtacggcatt cagaaacatc gttcattaac aaccggacgg ttgttgtacc
     7381 ccaacgcaca atatctgaag caatctggtg tttacagtgg atgcattctt gggctgtata
     7441 aatcaagttt ccacgataaa tatgacagat ttgccctttg tatttttctt ttgtgagaca
     7501 attttcgtta aaagtaactg ataagtctag aatatctaat gtttctttga taaggtgagt
     7561 gtaagacatc ttgattcctc cttttgggtt ggttcgccaa attaattcta aaggatttca
     7621 aggtgtcttt tctatatgtt ttggaaaata aaaaagatgc tggtgtcatc caccaacatc
     7681 aaaaagtata gagctaaaaa aattaaggaa cgtcaggcac aaggaatcga aattgctaag
     7741 aaaaaaggca aattcaaagg tcgtcagcat aaatttaaag aaaatgatcc acgtttaaag
     7801 catgctttcg atttgttttt gaatggttta tccgataaag aagttgaaga acaaactgga
     7861 atcaatcgcc gaacgtttag aaggtatcga gcaagatata acgtgacagt cgatcaaaga
     7921 aaaaacaatg aaaagaggga tagttaatga gtacggttat tttagctgaa aaaccaagcc
     7981 aggcattagc ctacgcaagt gctttaaaac aaagcaccaa aaaagacggt tattttgaga
     8041 tcaaagaccc actatttaca gatgaaacgt ttatcacctt tggttttggg catttagtgg
     8101 aattagcaga accaggtcat tatgacgaaa agtggcaaaa ttggaaactt gaatctttgc
     8161 cgatttttcc tgatcgatac gattttgaag ttgcaaaaga taagggaaag cagtttaaaa
     8221 ttgttgcaga acttctcaaa aaggcaaata caattattgt tgcaacagat agcgacagag
     8281 aaggtgaaaa tatcgcctgg tcgattatcc ataaagcaaa tgccttttca aaagataaaa
     8341 catttaaaag actatggatc aatagcttag aaaaagatgt aatccgaagc ggttttcaaa
     8401 atttgcaacc tggaatgaat tactatccct tttatcaaga agcgcaaaca cgccaaattg
     8461 ccgattggtt gatcggcatg aacgcaagcc ctttgtatac gttaaattta caacagaagg
     8521 gcgtacaagg tacattttca ctaggacgtg ttcaaacgcc caccttatac cttatttttc
     8581 agcgccagga agccatagag aattttaaaa aagaaccttt tttcgaggtg gaagctagta
     8641 taaaagtaaa ccaagggtcg tttaagggcg ttctaagccc cacacagcgt tttaaaaccc
     8701 aagaggagct tttagctttt gtttcttcta aacaagctaa aataggcaat caagagggga
     8761 taattgctga tgttcaaacc aaagagaaga aaacgaatag tccgagtttg ttttctttaa
     8821 gtagtttgca atcaaaagtc aatcagcttt ataaagcgac agcgagccaa actttaaaag
     8881 ctatgcaagg actgtatgaa gcaaaattat tgagttatcc aagaacagat acaccattta
     8941 ttacagagaa cgaatttgct tatttaaaag cgaattttgg caaatatagc ggttttttag
     9001 gacttgatct tgaaatggtt caaacagagc ctagaaagcg ttatgtggac ggtagtaagg
     9061 tacaggaaca ccacgccatt atcccaacaa aacaagtacc taccgaatct gcattagcga
     9121 aaatggacga tttacaacga aaaatttatg ctttagtcgt taaaacgacc gttgccatgt
     9181 ttttacctga ttacttgtat gaagaaacca agatacaaac gaaagtagct gatttgctgt
     9241 ttcaatcgat cggaaagaca ccaaagcaag aagggtggaa aattcttttc aaacaacaaa
     9301 ccaaagaaga aaaagaggac gttcaaacgt taccactcgt tatcattggc gaacgtgccg
     9361 aagttggtgt taagagtgtt gaaaaagaaa cgcaaccgcc aaaagctttt acagagggta
     9421 cattattaac tgctatgaaa acggcgaata aaacggttga tgatgaagaa gcaatcaaga
     9481 ttttacaaga agttgagggg attggaacag aagcgacaag agcaagtatt attgaagcgt
     9541 taaaacaaaa agaatatatc caagtgatta agaataagct tgttgtaact gaaaaaggaa
     9601 aattattgtg ccaggcagtt gaaagtcagc accttttaac gagtgctgaa atgacggcta
     9661 aatgggaaac gtatttaaaa aaaatcggta aaagagaagg caatcaagag aactttatta
     9721 cgaatatcaa aaaattcatt gttcatttac tggaagctgt acctaacgat atagaaaaac
     9781 taaatttttc tgattaccag gaacagaaag aaaaagaagc agaaaaaagt attgtaggaa
     9841 aatgtcctaa gtgtggcaac aatattgtat taaaaaaatc gttttatggt tgttcaaatt
     9901 atcctgaatg taagtttact ttagctgaac attttagaaa gaaaaaacta accaaaacga
     9961 atgtaaaaga attactggag ggaaaagaaa ccctggtaaa aggaatcaaa aacaaagaga
    10021 aaaagcccta caatgccgtt gtaaaaattg gggaaaaggg atatattgat tttatatctt
    10081 tctcaaaata aacataaaag ccctttaaag agggctttta tatattaatc acaaatcact
    10141 tatcacaaat cacaagtgat ttgtgattgt tgatgataaa ataagaataa gaagaaatag
    10201 aaagaagtga gtgattgtgg gaaatttagg cgcacaaaaa gaaaaacgaa atgatacacc
    10261 aatcagtgca aaaaaagata taatgggaga taagacggtt cgtgttcgtg ctgacttgca
    10321 ccatatcata aaaatcgaaa cagcaaagaa tggcggaaac gtaaaagaag ttatggaaat
    10381 aagacttaga agcaaactta agagtgtgtt gatagtgcat tatcttaaaa ttttgtataa
    10441 taggaattga agttaaatta gatgctaaaa atttgtaatt aagaaggagg gattcgtcat
    10501 gttggtattc caaatgcgta atgtagataa aacatctact gttttgaaac agactaaaaa
    10561 acagtgatta cacagataaa taaatacgtt agattaattc ctaccagtga ctaatcttat
    10621 gactttttaa acagataact aaaattacaa acaaatcgtt taacttctgt atttatttat
    10681 agatgtaatc acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt
    10741 ttaacgagtg aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat
    10801 accgtttacg aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt
    10861 aaacaggtaa cgtctattga attagacagt catctattca acttatcgtc agaaaaatta
    10921 aaactgaaca ttcgtgtcac tttaattcac caagatattc tacagtttca attccctaac
    10981 aaacagaggt ataaaattgt tgggaatatt ccttaccatt taagcacaca aattattaaa
    11041 aaagtggttt ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac
    11101 aagcgtacct tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt
    11161 cagcaattgc ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc
    11221 ttaataaaac ttacccgcca taccacagat gttccagata aatattggaa gctatatacg
    11281 tactttgttt caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt
    11341 catcaagcaa tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta
    11401 ttgtctattt ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt
    11461 ttgtaaatta taaaagaatt gttttaatgc aggtataaaa gatgaacccg caccaacacc
    11521 gccaccaatt ttagatagct ttgattggta catttttagc gctattcggg gtagcgtcag
    11581 gaaaatgcgg atttacaacg ctaagcctat tttcctgacg aatccctcgt ttttaacaac
    11641 gttaagaaag ttttagtggt cttaaagaat ttaatgagac tactttctct gagttaaaat
    11701 ggtattctcc tagtaaatta atatgttccc aacctaaggg cgacatatgg tgtaacaaat
    11761 cttcattaaa gctacctgtc cgttttttat attcaactgc tgttgttagg tggagagtat
    11821 tccaaatact tatagcattg ataattatgt ttaaagcact ggctctttgc aattgatgct
    11881 gtatggtgcg ttctctaagc tcaccttgtt ttccgaagaa aatagctctt gccaatccat
    11941 tcatggcttc tcctttattc aatcctcttt gtatttttct tcttaatgat tcatccgata
    12001 tataattcaa aataaagatc gttttttcta ttcggcccat ctcacgtaag gctgtagcta
    12061 agctgttttg tcttgaatag gaacctagct tccccataat aagggatgct gaaactgttc
    12121 cctcccttat agaatgagct aatcgcaaaa catcctcata attttcttta atgacctttg
    12181 tatttatttg tccacgtaaa atggcttcta gttttggata ctcacttgct ttatctatcg
    12241 taaataattt tgagtccgat aaatccctta ttcttggggc aaatttaaat cctaataaat
    12301 gagtcagtcc gaatatttgg tcagtgtaac cggcagtgtc tgtataatgt tcctctatgt
    12361 ttagatccgt ctcatgatgt aacaaaccat ccaaaacatg aatcgcatct cttgaattag
    12421 tatgaataat ctttgtgtag taagaagaga attgatcact tgtaaatcgg tagatggtgg
    12481 ctccttttcc agttccataa tgtggatttg catctgcatg tagtgatgaa acacctagct
    12541 gcattctcat accatctgac gaagatgttg taccgtcgcc ccaatagaaa ggcaattgta
    12601 atttatgatg aaagtttact aatatggctt gggctttatt catggcatct tcatacatgc
    12661 gccattgaga tacattggct agttgcttat atgtaagtcc gggtgtggct tcggccatct
    12721 tgctcaagcc aatattcatt cccattccta aaagggcagc catgataatg attgtttctt
    12781 ccttatctgg ttttcgatta ttggaagcat gagtgaattg ctcatgaaat cctgttatat
    12841 gggccacatc catgagtaaa tcagttaatt ttattcttgg tagcatctga taaaggcttg
    12901 cactaaattt ttttgcttct tctggaacat ctttttctaa gcgtgcaagt gatagctttc
    12961 ctttttcaag agaaacccca tctaacttat tggaattggc agctaaccac tttaaccttt
    13021 cattaaagct gctggttctc tccgttatat aatcttcgaa tgataaacta actgataatc
    13081 tcgtattccc cttcgattga ttccatgtat cttccgaaaa caaatattcc tcaaaatccc
    13141 tatattgtct gctgccaaca atggaaacat ctcctgcccg aacatgctcc cgaagttctg
    13201 ttaaaacagc catttcatag taatgacgat taattgttgt accatcatcc tcgtataaat
    13261 gtcttttcca tcgttttgaa ataaaatcca caggtgagtc atcaggcact tttcgctttc
    13321 cagattcgtt cattcctcgg ataatctcaa cagcttgtaa aagtggctca tttgcctttg
    13381 tagaatgaaa ttccaatact cttaatagcg ttggcgtata ttttcttagt gaataaaacc
    13441 gtttttgcag taagtctaaa taatcatagt cggcaggacg tgcaagttcc tgagcctctt
    13501 ctactgaaga gacaaaggta ttccattcaa taaccgattc taaaacctta aaaacgtcta
    13561 atttttcctc tcttgcttta attaatgctt gtccgatgtt cgtaaagtgt ataactttct
    13621 catttagctt tttaccgttt tgtttctgga tttcctcttg agccttacga ccttttgata
    13681 acaaactaag tatttgccta tcatgaattt caaacgcttt atccgttagc tcctgagtaa
    13741 gttgtaataa atagatggtt aatatcgaat aacgtttatt ttcttgaaag tcacggaatg
    13801 catacggctc gtatcttgag cctaagcgag acagctgcaa caggcggtta cggtgcaaat
    13861 gactaatttg cactgtttct aaatccattc ctcgtatgta ttcgagtcgt tctattattt
    13921 ttagaaaagt ttcgggtgaa ggatgacccg gtggctcttt taaccaaccc aatatcgttt
    13981 tattggattc ggatggatgc tgcgaggtaa taatcccttc aagcttttct ttttgctcat
    14041 ttgttagaga tttactaacc gtattaaata gcttcttttc agccattgcc cttgcttccc
    14101 acaccattct ttcaagtgta gtgatagcag gcagtataat tttgtttttt cttagaaaat
    14161 ctatgcattc atgcagtaga tgaatggcat caccattttc caaagctaat tgatgaaggt
    14221 acttaaatgt cattcgatat tcactcaggg taaaagttac aaagtcgtat tcacttcgaa
    14281 tttctttcaa atgatcccaa agtgtatttt ccctttgagg ataatgatca agcgaggatg
    14341 gactaacacc aatctgtttc gatatatatt gtatgaccga atctgggatg cttttgatat
    14401 gagtgtatgg ccaaccggga taccgaagaa cagctaattg aacagcaaat cctaaacggt
    14461 tttcttccct ccttcgctta ttaactattt ctaaatcccg tttggaaaaa gtgaagtagg
    14521 tccccagtat ccattcatct tcagggattt gcataaaagc ctgtctctgt tccggtgtaa
    14581 gcaattctct acctctcgca attttcattc agtatcattc catttctgta ttttcaattt
    14641 attagttcaa ttatatatca atagagtgta ctctattgat acaaatgtag tagactgata
    14701 aaatcatagt taagagcgtc tcataagact tgtctcaaaa atgaggtgat attttgcgga
    14761 aaatcggtta tattcgtgtc agttcgacta accagaatcc ttcaagacaa tttcagcagt
    14821 tgaacgagat cggaatggat attatatatg aagagaaagt ttcaggagca acaaaggatc
    14881 gcgagcaact tcaaaaagtg ttagacgatt tacaggaaga tgacatcatt tatgttacag
    14941 acttaactcg aatcactcgt agtacacaag atctatttga attaatcgat aacatacgag
    15001 ataaaaaggc aagtttaaaa tcactaaaag atacatggct tgatttatca gaagataatc
    15061 catacagcca attcttaatt actgtaatgg ctggtgttaa ccaattagag cgagatctta
    15121 ttcggatgag acaacgtgaa gggattgaat tggctaagaa agaaggaaag tttaaaggtc
    15181 gattaaagaa gtatcataaa aatcacgcag gaatgaatta tgcggtaaag ctatataaag
    15241 aaggaaatat gactgtaaat caaatttgtg aaattactaa tgtatctagg gcttcattat
    15301 acaggaaatt atcagaagtg aataattagc cattctgtat tccgctaatg ggcaatattt
    15361 ttaaagaaga aaaggaaact ataaaatatt aacagcctcc tagcgatgcc gaaaagccct
    15421 ttgataaaaa aagaatcatc atcttaagaa attcttagtc atttattatg taaatgctta
    15481 taaattcggc cctataatct gataaattat taagggcaaa cttatgtgaa agggtgataa
    15541 ctatgagcga taaaatactt attgtggatg atgaacatga aattgccgat ttggttgaat
    15601 tatacttaaa aaacgagaat tatacggttt tcaaatacta taccgccaaa gaagcattgg
    15661 aatgtataga caagtctgag attgaccttg ccatattgga catcatgctt cccggcacaa
    15721 gcggccttac tatctgtcaa aaaataaggg acaagcacac ctatccgatt atcatgctga
    15781 ccgggaaaga tacagaggta gataaaatta cagggttaac aatcggcgcg gatgattata
    15841 taacgaagcc ctttcgccca ctggagttaa ttgctcgggt aaaggcccag ttgcgccgat
    15901 acaaaaaatt cagtggagta aaggagcaga acgaaaatgt tatcgtccac tccggccttg
    15961 tcattaatgt taacacccat gagtgttatc tgaacgagaa gcagttatcc cttactccca
    16021 ccgagttttc aatactgcga atcctctgtg aaaacaaggg gaatgtggtt agctccgagc
    16081 tgctatttca tgagatatgg ggcgacgaat atttcagcaa gagcaacaac accatcaccg
    16141 tgcatatccg gcatttgcgc gaaaaaatga acgacaccat tgataatccg aaatatataa
    16201 aaacggtatg gggggttggt tataaaattg aaaaataaaa aaaacgacta ttccaaacta
    16261 gaacgaaaac tttacatgta tatcgttgca attgttgtgg tagcaattgt attcgtgttg
    16321 tatattcgtt caatgatccg agggaaactt ggggattgga tcttaagtat tttggaaaac
    16381 aaatatgact taaatcacct ggacgcgatg aaattatatc aatattccat acggaacaat
    16441 atagatatct ttatttatgt ggcgattgtc attagtattc ttattctatg tcgcgtcatg
    16501 ctttcaaaat tcgcaaaata ctttgacgag ataaataccg gcattgatgt acttattcag
    16561 aacgaagata aacaaattga gctttctgcg gaaatggatg ttatggaaca aaagctcaac
    16621 acattaaaac ggactctgga aaagcgagag caggatgcaa agctggccga acaaagaaaa
    16681 aatgacgttg ttatgtactt ggcgcacgat attaaaacgc cccttacatc cattatcggt
    16741 tatttgagcc tgcttgacga ggctccagac atgccggtag atcaaaaggc aaagtatgtg
    16801 catatcacgt tggacaaagc gtatcgactc gaacagctaa tcgacgagtt ttttgagatt
    16861 acacggtata acctacaaac gataacgcta acaaaaacgc acatagacct atactatatg
    16921 ctggtgcaga tgaccgatga attttatcct cagctttccg cacatggaaa acaggcggtt
    16981 attcacgccc ccgaggatct gaccgtgtcc ggcgaccctg ataaactcgc gagagtcttt
    17041 aacaacattt tgaaaaacgc cgctgcatac agtgaggata acagcatcat tgacattacc
    17101 gcgggcctct ccggggatgt ggtgtcaatc gaattcaaga acactggaag catcccaaaa
    17161 gataagctag ctgccatatt tgaaaagttc tataggctgg acaatgctcg ttcttccgat
    17221 acgggtggcg cgggacttgg attggcgatt gcaaaagaaa ttattgttca gcatggaggg
    17281 cagatttacg cggaaagcaa tgataactat acgacgttta gggtagagct tccagcgatg
    17341 ccagacttgg ttgataaaag gaggtcctaa gagatgtata taatttttta ggaaaatctc
    17401 aaggttatct ttactttttc ttaggaaatt aacaatttaa tattaagaaa cggctcgttc
    17461 ttacacggta gacttaatac cgtaagaacg agccgttttc gttcttcaga gaaagatttg
    17521 acaagattac cattggcatc cccgttttat ttggtgcctt tcacagaaag ggttggtctt
    17581 aattatgaat aacatcggca ttactgttta tggatgtgag caggatgagg cagatgcatt
    17641 ccatgctctt tcgcctcgct ttggcgttat ggcaacgata attaacgcca acgtgtcgga
    17701 atccaacgcc aaatccgcgc ctttcaatca atgtatcagt gtgggacata aatcagagat
    17761 ttccgcctct attcttcttg cgctgaagag agccggtgtg aaatatattt ctacccgaag
    17821 catcggctgc aatcatatag atacaactgc tgctaagaga atgggcatca ctgtcgacaa
    17881 tgtggcgtac tcgccggata gcgttgccga ttatactatg atgctaattc ttatggcagt
    17941 acgcaacgta aaatcgattg tgcgctctgt ggaaaaacat gatttcaggt tggacagcga
    18001 ccgtggcaag gtactcagcg acatgacagt tggtgtggtg ggaacgggcc agataggcaa
    18061 agcggttatt gagcggctgc gaggatttgg atgtaaagtg ttggcttata gtcgcagccg
    18121 aagtatagag gtaaactatg taccgtttga tgagttgctg caaaatagcg atatcgttac
    18181 gcttcatgtg ccgctcaata cggatacgca ctatattatc agccacgaac aaatacagag
    18241 aatgaagcaa ggagcatttc ttatcaatac tgggcgcggt ccacttgtag atacctatga
    18301 gttggttaaa gcattagaaa acgggaaact gggcggtgcc gcattggatg tattggaagg
    18361 agaggaagag tttttctact ctgattgcac ccaaaaacca attgataatc aatttttact
    18421 taaacttcaa agaatgccta acgtgataat cacaccgcat acggcctatt ataccgagca
    18481 agcgttgcgt gataccgttg aaaaaaccat taaaaactgt ttggattttg aaaggagaca
    18541 ggagcatgaa tagaataaaa gttgcaatac tgtttggggg ttgctcagag gagcatgacg
    18601 tatcggtaaa atctgcaata gagatagccg ctaacattaa taaagaaaaa tacgagccgt
    18661 tatacattgg aattacgaaa tctggtgtat ggaaaatgtg cgaaaaacct tgcgcggaat
    18721 gggaaaacga caattgctat tcagctgtac tctcgccgga taaaaaaatg cacggattac
    18781 ttgttaaaaa gaaccatgaa tatgaaatca accatgttga tgtagcattt tcagctttgc
    18841 atggcaagtc aggtgaagat ggatccatac aaggtctgtt tgaattgtcc ggtatccctt
    18901 ttgtaggctg cgatattcaa agctcagcaa tttgtatgga caaatcgttg acatacatcg
    18961 ttgcgaaaaa tgctgggata gctactcccg ccttttgggt tattaataaa gatgataggc
    19021 cggtggcagc tacgtttacc tatcctgttt ttgttaagcc ggcgcgttca ggctcatcct
    19081 tcggtgtgaa aaaagtcaat agcgcggacg aattggacta cgcaattgaa tcggcaagac
    19141 aatatgacag caaaatctta attgagcagg ctgtttcggg ctgtgaggtc ggttgtgcgg
    19201 tattgggaaa cagtgccgcg ttagttgttg gcgaggtgga ccaaatcagg ctgcagtacg
    19261 gaatctttcg tattcatcag gaagtcgagc cggaaaaagg ctctgaaaac gcatttataa
    19321 ccgttcccgc agacctttca gcagaggagc gaggacggat acaggaaacg gcaaaaaaaa
    19381 tatataaagc gctcggctgt agaggtctag cccgtgtgga tatgttttta caagataacg
    19441 gccgcattgt actgaacgaa gtcaatactc tgcccggttt cacgtcatac agtcgttatc
    19501 cccgtatgat ggccgctgca ggtattgcac ttcccgaact gattgaccgc ttgatcgtat
    19561 tagcgttaaa ggggtgataa gcatggaaat aggatttact tttttagatg aaatagtaca
    19621 cggtgttcgt tgggacgcta aatatgccac ttgggataat ttcaccggaa aaccggttga
    19681 cggttatgaa gtaaatcgca ttgtagggac atacgagttg gctgaatcgc ttttgaaggc
    19741 aaaagaactg gctgctaccc aagggtacgg attgcttcta tgggacggtt accgtcctaa
    19801 gcgtgctgta aactgtttta tgcaatgggc tgcacagccg gaaaataacc tgacaaagga
    19861 aagttattat cccaatattg accgaactga gatgatttca aaaggatacg tggcttcaaa
    19921 atcaagccat agccgcggca gtgccattga tcttacgctt tatcgattag acacgggtga
    19981 gcttgtacca atggggagcc gatttgattt tatggatgaa cgctctcatc atgcggcaaa
    20041 tggaatatca tgcaatgaag cgcaaaatcg cagacgtttg cgctccatca tggaaaacag
    20101 tgggtttgaa gcatatagcc tcgaatggtg gcactatgta ttaagagacg aaccataccc
    20161 caatagctat tttgatttcc ccgttaaata aacttttaac cgttgcacgg acaaactata
    20221 taagctaact ctttcggcag gaaacccgac gtatgtaact ggttcttagg gaatttatat
    20281 atagtagata gtattgaaga tgtaaggcag agcgatattg cggtcattat ctgcgtgcgc
    20341 tgcggcaaga tagcctgata ataagactga tcgcatagag gggtggtatt tcacaccgcc
    20401 cattgtcaac aggcagttca gcctcgttaa attcagcatg ggtatcactt atgaaaattc
    20461 atctacattg gtgataatag taaatccagt agggcgaaat aattgactgt aatttacggg
    20521 gcaaaacggc acaatctcaa acgagattgt gccgtttaag gggaagattc tagaaatatt
    20581 tcatacttcc aactatatag ttaaggagga gactgaa
//
LOCUS       DACCVZ010000047        20496 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.047, whole genome shotgun sequence.
ACCESSION   DACCVZ010000047 DACCVZ010000000
VERSION     DACCVZ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.047"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            72..3461
                     /locus_tag="IVW63_001750"
     CDS             72..3461
                     /locus_tag="IVW63_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAP7860026.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYRKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            3464..4885
                     /locus_tag="IVW63_001751"
     CDS             3464..4885
                     /locus_tag="IVW63_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP7860027.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            4882..6759
                     /locus_tag="IVW63_001752"
     CDS             4882..6759
                     /locus_tag="IVW63_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP7860028.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            6851..7693
                     /locus_tag="IVW63_001753"
     CDS             6851..7693
                     /locus_tag="IVW63_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP7860029.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(7845..8720)
                     /locus_tag="IVW63_001754"
     CDS             complement(7845..8720)
                     /locus_tag="IVW63_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP7860030.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            8927..9958
                     /locus_tag="IVW63_001755"
     CDS             8927..9958
                     /locus_tag="IVW63_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAP7860031.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            10047..10352
                     /locus_tag="IVW63_001756"
     CDS             10047..10352
                     /locus_tag="IVW63_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HAP7860032.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            10531..12546
                     /locus_tag="IVW63_001757"
     CDS             10531..12546
                     /locus_tag="IVW63_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP7860033.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            12548..12832
                     /locus_tag="IVW63_001758"
     CDS             12548..12832
                     /locus_tag="IVW63_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7860034.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            12858..14231
                     /locus_tag="IVW63_001759"
     CDS             12858..14231
                     /locus_tag="IVW63_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAP7860035.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(14314..16329)
                     /locus_tag="IVW63_001760"
     CDS             complement(14314..16329)
                     /locus_tag="IVW63_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HAP7860036.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16351..17565)
                     /locus_tag="IVW63_001761"
     CDS             complement(16351..17565)
                     /locus_tag="IVW63_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7860037.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            17786..18730
                     /locus_tag="IVW63_001762"
     CDS             17786..18730
                     /locus_tag="IVW63_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7860038.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            19026..19970
                     /locus_tag="IVW63_001763"
     CDS             19026..19970
                     /locus_tag="IVW63_001763"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAP7860039.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
BASE COUNT         7007 a         3753 c         3887 g         5849 t
ORIGIN      
        1 gtaacgcctg tttattttaa taattttcac tattcacgtc aaaacagaaa aaaagaaaaa
       61 ggaggggaaa aatgacgacc acagggaaga aactgaaagt tattttcatg ctgataatat
      121 tgagtttatc aaactttgtg ccattatctg caatagcaga cactacagat gatccaacag
      181 ttttagaaac aatttcagct gaagtcattt cggatcagtc tggaaaaaaa gcactgaaca
      241 tcaagctaaa tgcgaataac accagtgctg aaaagataga aaaagaaatt ggtctagtcg
      301 aaaattactt aagtgatgtg gaaagaaaag aaggagatgg ctatgcttat caggtaaata
      361 gcgggaaaat tacgttggaa atctcatcaa acactaaaca aactatcgat ctgagttttc
      421 caatcgatcc agcactttac cacagccagg caaacaagct gatcgtcgat aataaagaat
      481 atgacattat tgatgagaca gaaaataaga aagatacaga tgtgtcagta ccaaagccag
      541 acgaaataga agaagaatca tcaaaagaaa acgaaaattc tgtcagccca tttacattgc
      601 ctacattatc cttgccagct gtgagtgtgc catctaatca aacgattcct acagaatata
      661 caacagatga tcagggcact tatcctaaag ccagttggca acctacagga aatacaaatg
      721 ttcttgatca tcaaggcaat aaaaacggaa caaatcaatg ggatggtata aattcttgga
      781 atggagatcc taatgatcgg acccattcgt atatcgaata tggaggaacc ggtaatcaag
      841 cagactatgc gatacgaaag tatgcaaagg aaacaagtac acccggattg tttgatgttt
      901 atttgaatgc tcgtggaaat gtacaaaaag atatcacgcc tcttgatctc gtattggtcg
      961 tagactggtc aggaagtatg aacgacaata atcggatcgg tgaagtaaag attggtgtcg
     1021 atcgttttgt cgatacttta gcagatagcg gtatcacaga caaaatcaat atgggatatg
     1081 tcggctactc aagcgaagga tatagctaca gtaacggtgc agtacagatg ggttcatttg
     1141 attcagtgaa aaatcaagta aaatccatta caccttcacg gacaaatggt ggtactttta
     1201 cacaaaaagc actaagagat gcaggaagca tgctatccgt tccaaatgga cataaaaaag
     1261 tgatcgtttt gctgacggat ggtgtaccaa cattttccta taaagtacag cgggtacacg
     1321 cacaatcaag cagcaattat tacggaactc agttttctaa tacgcaagat cggccgggaa
     1381 atacttctct aatctcaaga atctatgatg cacctgacca aaacaatcta tccagaagaa
     1441 tcgacagtac gtttatcgca accatcggag aagcgatggc actcaaagaa cgaggaatcg
     1501 aaatacatgg tcttggcatc caacttcaaa gcgatccggc agctggtctc tcaaaagcag
     1561 aagtagagtc tcgtatgcga caaatggttt catcagatga aaaaggcgat ctttactatg
     1621 aatcagctga tcatgcaaca gatatctctg aatacctagc caaaaaagct gtacagatct
     1681 cagcaactgt aagcaatgga caaataaatg atccaatcgc agaaccattc atttatcagc
     1741 ctggtacact ttcagtcaag agtgtgggga caagtcctac aacggtcact ccatctattt
     1801 ccatagaagg aaataccatc aagagcaatc agatctattt aggaaaagac caagaaatcc
     1861 aaatccatta ccaagtgaga atccaaacag aaaatgagga cttccatcca aatttctggt
     1921 atcaaatgaa cggcaggaca actttccagc caaacattga taccaatgaa ttagctgaat
     1981 tcggtatacc atctgctaaa gctcccggag tcagtcttca catcaaaaag ttatgggaag
     2041 aatttgacaa caatctagct gatcgtccag atcaagttac ttttgagatt caacgggaac
     2101 atacgacaaa tgctgcagct tggaaaaacg gatatattcg aatcattaaa ccagctaaag
     2161 atacaacaaa tacgtgggaa cgtgcagaca ttgacaaatt atctgcaaat agcggagaaa
     2221 gttatcaaga gatattatca ctacctcaat acaataatca aggtcaagca ttcagttacc
     2281 aaacaatcaa agaattacct gtaccaggat acgattctca acaaatagat gcaatgacat
     2341 ggaaaaatac taaacaattc acaccgttaa acttgaaaat aacgaaaaat tcctctacag
     2401 gtgaaaagga tcttattggc gctgttttca aattaacagg agattctatt gatactttac
     2461 taacagatca tggcgacgga acctattctc ttccagaaaa tgtcaaattg caaaaagaaa
     2521 tgacctatac gctgacagaa acaaaagctc cagaagggca tggattaagc aaaaagacta
     2581 cttgggaaat caagatcgct tctgatggta cggtaaccat tgatggaaaa acagtcacta
     2641 cttccgatga tacgatccag ttgactattg aaaatccttt tgttgaagtt cctgtagcag
     2701 tacgtaagta tgcgatgcaa gggacggaca aagagataaa tcttaaagga gcagcatttt
     2761 ccctacagaa aaaagaagca aatggtactt atcagccaat tgacagccaa acaacgaatg
     2821 aaaaaggtct tgccagtttt gattcactca cacctggtaa atatcgagtc gttgaaacag
     2881 ctggtcctgc cggatatgat acttcgccgg gaaattatga attccaaatc gataaatata
     2941 gaaaaatcat ttacacggga aaaaataccg agatgacaaa taatgtatgg acgctcactc
     3001 atcaaaatcg actaaaagcg tttgatctaa cggtacacaa aaaagaagac aacggacaga
     3061 cattaaaagg agcaaaattc agactgcagg gaccagaaat ggacttagaa tcgccaaaag
     3121 atggacaaga aacagatacc tttctattcg aaaatttaaa acctggaact tatacgctga
     3181 ccgaaacttt tacaccagaa ggataccaag gtctaaaaga gccagttact atagttatac
     3241 acgaagatgg gtcaattcaa gtggatggac aagatcatga atctgttctg tcaccaggag
     3301 ccaaaaacaa ccagatttct ttagacatca cgaatcaggc aaaagtacca ttacctgaaa
     3361 cgggaggaat tggccgttta ggaatctatc tagtagggat gattggttgt gcgttttcta
     3421 tttggtatct ttttttgaaa aaagaaagag ggggcagcta aatatgaaaa aacttggttg
     3481 gcttagtatg tgtctcttct tgttactatt taaaccagct tttactcagg tagcaacaga
     3541 aacagaaaca gaaatggttc agattacttt acacaaattg cttttcccaa acgggcaact
     3601 gccgaaaaat catccaaatg acggacaaga aaaagcttta ttacaaacgt atcgaggatt
     3661 aaatggtgtc acattccaag tttatgatgt cacagattct ttttaccatc tacgggaaaa
     3721 gggcaaaacg gtagaagaag cacaagcaga gatcgcaaaa aacggtgcgt cttccggtat
     3781 gtttaccgca gaagcaacaa ctacaactct taacaacgaa gatggtatcg cttctttttc
     3841 tctggccgct aaagatcaag aaaaaagaga taaagcgtat cttttcattg aatccaaagt
     3901 accagaagtc gtcaaagaaa aggcagagaa tatggtagtt gttcttcctg tacatggaca
     3961 aaacaatcaa aaactttcaa ctatccattt gtatcctaaa aatgaagaaa acgactaccc
     4021 tgatccacct tttgagaagg tattagaaga gcctagaaat gattttacga ttggtgaaaa
     4081 aatcacttat tccttgcata cgacaattcc tgtaaatatc cttgactatc aaaagttcga
     4141 attgtcagat agtgcggatg aagcattaac gtttttacct aatagtttaa cgatttcatc
     4201 gaatggagaa aagctgacag aaggctttgt catacacaag aaacctcacg gatttgatgt
     4261 tttattttcg atcccttcgt tggaaaaata tgctggaaaa aaactgacca tttcttatca
     4321 gatgcagcta agcagtacag cacaggcgaa caaggaaatc aacaacaacg gaacactgga
     4381 ttttggtttt ggtgtcagta caaagaaagt ctctgtatat acagggagta agcaatttgt
     4441 caaaatcgag acaaataaac cagataaacg attagctggc gcagtattcc ttattaaaaa
     4501 caaagcagga aattacctcc agcaaacagc caacggatac aagtggacaa agaacgaatc
     4561 agatgcgctt cacctgattt ccgataaaaa tggcgctttt tcaatttccg ggttgaaaac
     4621 aggaagttat cgattaaaag agatcgaagc accttctggt tatattttaa gtgaaacaga
     4681 aattccgttt accatttcaa cttttctttc tgaggataaa gaggcggaca gtatattgaa
     4741 agtagtcaat aaaaaagaaa atagccgtcc atttcttcca aaaacaaacg aaacgaaaaa
     4801 tacactttta ggcgttgttg gtatggtatt cgcaagcttt gcaatctggt tgtttatcaa
     4861 aaaaagaaca ggagtgaaaa aatgaaaaat cataaaaaaa taaacgttat gttaggagtc
     4921 cttttcctta ttttaccatt actcacaaac agcttcggcg caaaaaaagt gtttgcagag
     4981 gagacagcag ctcaagtcat ccttcataaa aagaaaatga ctgatttacc cgatccttta
     5041 atccaaaaca gcgggaaaga aatgagcgaa ttcgatcaat accaaggatt agccgatatt
     5101 tcattttcag tttataacgt cactcaagaa ttttatgcgc aacgagataa aggagcgtcc
     5161 gtggatgcag caaaacaagc agtccagtct ttgactcctg gtacaccagt tgcttcagga
     5221 acgacagatg ctgatggaaa tgtcacttta tctttaccta aaaaacaaaa tgggaaagat
     5281 gcagtctaca cgatcaaaga agaaccaaaa gacggagtgt cagctgccgc aaacatggtt
     5341 ttagctttcc ctgtatatga gatgatcaaa caagcagatg gctcttataa atacgggaca
     5401 gaagaactag atactatcca tctctaccct aaaaatacag tcggtaatga tggaacgttg
     5461 aaagttacaa aaatcggtac tgccgaaaac gaagcactaa atggagcaga atttattatt
     5521 tctaaagaag aaggaacacc aagcgtcaaa aaatacatcc aaagtgtcac agatggattg
     5581 tacacttgga caactgatca aaccaaagcc aaacatttca ttactggtca ttcttatgac
     5641 atcggcaaca atgactttgc cgaggcatct attgaaaaag gccagttgat cgttaatcat
     5701 ttagaagttg gaaaatataa tttagaagaa gtaaaagctc ctgataatgc ggaaatgatt
     5761 gaaaagcaaa caatcacgcc ttttgagatc ctggcaaata gccaaacacc agtagaaaag
     5821 accatcaaaa atgatacgtc taaagttgat aaaacaacac ctcaattgaa tggaaaagat
     5881 gtcgcaatcg gtgaaaaaat tcaatatgag atttctgtca atatcccatt aggtatcgct
     5941 gataaagaag gaacgcaaaa caagtacaca acattcaaac ttatcgatac tcatgacgct
     6001 gctttaacat ttgataatga ttcttcagga acgtatgctt atgccttata tgatggaaat
     6061 aaagaaatcg acccagtaaa ttattctgtc actgagcaaa cagacggatt cacggtttca
     6121 gttgatccga attatattcc ttcattaact cctggcggta cattgaaatt cgtttactat
     6181 atgcatttga acgaaaaagc agatccaacc aaaggatttt ctaaccaagc aaatgtcgat
     6241 aacgggcata caaatgatca aacaccaccg tcagtcgatg tcgttactgg gggcaaacga
     6301 tttgttaaag tagatggtga cgttacatca gaccaaacac ttgctggagc agaattcgtc
     6361 gttcgtgatc aagatagtga cacagcgaaa tatttatcga tcgacccatc cacaaaagcc
     6421 gtcagctggg tatcggcgaa agaatcagca acggttttta caaccacaag taacggttta
     6481 atcgatgtga caggtctaaa atatggcacg tactatctgg aagaaacgaa agcgccagaa
     6541 aaatatgttc cattaacaaa ccgtgtagca tttactatcg atgaacaatc ttatgtaaca
     6601 gcaggacagt tgatttctcc tgaaaaaata ccaaataaac acaaaggtac acttccttca
     6661 acaggcggta agggaatcta tgtgtatatc ggtgcaggag tagtccttct actgattgct
     6721 ggactgtact ttgctagacg caagcacagt cagatttagt ctttttgcaa gaattggaaa
     6781 aaggagcagc ggattacgca aatgctcctt tttcttttat tatcaaacag tcatcacaag
     6841 gagaacacaa atgaaaccaa agaaaaggaa acttctagat ctgctgatgc ttttcttgct
     6901 tctctcagga atagggatac tagcttatcc atttgttagc gacgcgctga ataattatct
     6961 ggatcagcag atcatctctc attatcagca acaagcggtc aaagaaaatg aagaagtcat
     7021 ggctaaaatc caagaaaaca tgacaaagaa aaaccagcaa ttagcaaaag aaggtggaaa
     7081 tccaggtgca gatcccttta ctaagaaaaa agaacctgcg aaaaaggata gaacctattt
     7141 tgagaaacat acgatcggta ttttgacgat ccctgagatc aatgtccatt tgccaatttt
     7201 tgatgaaacg aatactgtgc tgctagaaaa aggtgcctca ttattggaag gaacgtctta
     7261 tcctacgggg ggagaaaata cacatgccgt tatttccagc catcgaggac tgcctcaagc
     7321 aaagttgttc acagacttac cgaaactgac tttaggtgat tctttctata tcgaaatcaa
     7381 tggacggaca ctcgcttatc aagtcgatca gatcaagacg gtagaaccga ctgatacaaa
     7441 agatctgaga atcgaaaaag ggcaggattt cgtgacactc ctaacttgta caccttatat
     7501 ggtcaacagt catcgcttac ttgtcagagg gcaccgggtt ccttatcatg caaaagaagt
     7561 tcaaaaagaa gtacagaaag tatccgagaa caaacgattt ttcctgtatg gattgttagc
     7621 tgcatgtata ctgattttcc tccttcttat atatcttttt cgtcaatcgt tcaaaataag
     7681 aaacagaagt tagctattcc tcatttctat aatatatcta ttcgaatcgt tccgtaaaca
     7741 aacaggctga ggtttgaaaa agaaaacttc agcctgtttt tatgatgata tcaaagagag
     7801 cctatcaaac actatctttc ttattactaa atgaggatct tttcttaagt tttccgatat
     7861 tctttaagaa ggcctttttg catcaattct tgtttgtttt tcaagttgcg gatattctct
     7921 tcaaaatttt gagaatatat cactgagaat aacgtattta atacgtaatc gaaggcaatt
     7981 tgagaggaga aagtcgctac tttagcaaaa tcatattcct cctgcgatat aacaagacac
     8041 atatcagcct gtttggccat ttctgaatgc tgatttccgg taatcagcaa ggtaggggcc
     8101 tctacatgct tcaaataggt cattattcgt tcataatgat ggatgcgacc gctgtagcta
     8161 ataaaaatgg cgcaatcctc gctagtcaaa ttggctgcat tccaagaaga atcactgtat
     8221 tcttcagcca tgatcaaaaa cttattcaac ttgaccattt tattctggaa tttccttgcc
     8281 gtgatttgag aatcaccttt tgcaaaaaga aagattcgct gtgccttgtt caatacttta
     8341 ccgatttgat ctaaatcttc atgttcaatc tgcaattgtg ctttttttat tgactggatc
     8401 gataaatccg ccattttctt tgcaatttgc tgagtgctat cttcacttga aaaaggaaaa
     8461 ttaggatcaa tcgtttgatt gaactgagca atcaattgat gaacttcccg ccccagctcg
     8521 aaacggaatt ctttaaatcc gctgaatccc atttttttgc ataaacgaat gatagctgaa
     8581 tgggaagtat acgtagcttt tgctaattct tcaatcgtca tgtagactgc agcttcgata
     8641 ttcctacgga tgtaatcgac aatccgtttc tctgtcgtgg taaacaactc ttgttttgtt
     8701 agtttttctt caataagcat gatctgacct ccaaattcta tcttactgat aaacacttgg
     8761 ttccgctact atctttttga tttttatcct tactttgaac attaatttca ccaaaccgaa
     8821 tgataacaag tgtttttctg aactttttta ccagaatagc tattataaat actttctgcg
     8881 cttttctagg atatactgaa aacatcaata aaaggaggca ccactcatgc ttacaatcgc
     8941 ttatcttggc aatggaaaga gtacaaatcg ctatcatttg cctttttcaa gaaaacttac
     9001 gaacaaaatc aatatcaaaa aaattttttc cccatctgaa ccagtgtgga aaacattcga
     9061 agacatcgaa tatactgatc agctgtctga tctttgggat gatcctgaga tccaattagt
     9121 tgtcatcact acacctagtc aatttcatta tgaatatgga aaaatggcac tcgaacatgg
     9181 taagaatgta ctagtagaga aaccttttgc agaaacgtca aaggaagcag aagagttatt
     9241 tgcattagca aaagaaaaag gtctatttat ccaatgttac caaaacagac ggttcgattc
     9301 tgacttcttg acagtccaaa aagtaatcga aagcggaaaa ttaggggata ttttagaagt
     9361 agaaatgcat tatgattatt tcagaccgga agtaccagaa aatacgcatg aattttctac
     9421 tgcgaacagc tatttatatg gacatgcttg tcatacagta gatcaagttc tttcttattt
     9481 cggcgaacca gatgatatca gctatgatgt acgtcaactt ttagggaaag gacgaatgaa
     9541 tgattacttc gatctggatt ttttctatgg aaatatgaaa atttcgataa aatccagtta
     9601 tttccgcatc aaagaacgtc caagtttcgt cgtttacgga aaaaaaggga tgttcgtgaa
     9661 acaaacaaaa gatcgacaag aagaacatct gaaaatgttt tacatgcctg atcatgaaga
     9721 ctttggtatc gatttgcccg aacattatgg tgtattgacc tatatagatg aacaagggag
     9781 ttatcatgaa gaaaaagtaa tttccgaggt tggtgattac agccgtgtct acgaagggat
     9841 ttacgagaca ttagttaatg gcgcagaaaa agtcatcaaa gatgaagaaa caatcttaca
     9901 aatgaaaatt ttggaagaag gaatcaaaag cattcaagaa tcagaaggaa aaatatgaca
     9961 tatttgtaag aatcgggttt gttttttgac gcataaactg tcttattgta cgatgaaaaa
    10021 gtatagaact actaggagga accaacatga caaattatga cggtgaaaaa cacaaacgat
    10081 taagaggttc aatggcccct aaaacagaag aagaagtggc tttagcagga actaattctg
    10141 gtgaaacaga agacaaagaa gaatcattag ctggcacaaa ctctggtgaa acagaaaata
    10201 aagaaacagc tttatctggt tcaaattctg tagaagagga aacaaagcct aatgagccca
    10261 atcactttga aaaagatatc gaaaaagcgg ttgaagatgt caaagaaaaa tttgaagaac
    10321 tgacctcaaa aaataaacat gatcatcatt gatcggacga aatcaattca taaaagcagg
    10381 agacatttgg tcacctgctt tttttctgta tccattcgat agaaatcgtt cggtacagtc
    10441 gtaaaaaaaa tccaactgta agttgtacca aacacccctc gatttaaaag cgctaccata
    10501 ctagaatata agtaggaggt gaacagcgct gtgaactaca aaattagtta tctcctgaaa
    10561 acaccaagag aaatcagtct agaaaaagca gcagagatca tcgaagtaaa tacaagcgag
    10621 gcgatcaaac aattaactcc ttttgccgaa tatgtggatg atacccgtat ccgtataaag
    10681 aaattccgag caatcgactg ggcagaaaaa tttttggata ttactcgatt tgaagctgtg
    10741 tataccgaac aagagcgaag agatcttctt tatttgatgg tttattcgac tgcaacgtct
    10801 gtttctgttt ttcattttca agattttctt caggtttcta aagggacagt cctgtcagat
    10861 atcaaaaaga taagaaatga attagaagtg gaagattgtc agctgtcgta tactaggaaa
    10921 actggtttta ggctgctagg gtcagaagca atattaagaa gagaagcaaa aaatcgcact
    10981 gctcgtttga tgcagtcact tgctggaaga tttgggctca cgtatttaac cgcaaccctt
    11041 tccattgatt attacgccaa agttagagat ttgctagata aaacgatttc actatcagat
    11101 cttcgattcg caccaaatcg aatggatgaa ttagcttatt atttgagttt gacaaccatt
    11161 cgaattggaa aaacatccat ggaactggta aaagatgctg aactgttggc ttctcttgca
    11221 gtcactgaca ttagtcgaca agtattgact ggccttggct attccgaaca tcaaaattcg
    11281 gagattatat ttttctctct ttgcttagca tcgatcgttg aaggagatgt ccaggagcct
    11341 gcacttgatt ttttgctgga atgttcttca gaagtcatcc atcgcatgga attcctgatg
    11401 gccgtagaat ttgcttcgtt tcgtgaatta ttgatgaatg tcttttatca cttggtccct
    11461 gcctattttc gtatttccta ttctttttat ttacctaatg tgatgatcga tcaaattaag
    11521 catcaatatg cttccatcta cgaaatgaca agaaaagcat tacttccgtt agaaagacga
    11581 atagggaaga gcatccctga agaagagatt ggttttttca ctatactatt tggcggagag
    11641 atcagaaaag cggacgcaga agaaagaaat agaaaaataa gagccgtgat cgtctgtcca
    11701 agtggcatta gctcttcatt gatcttaaaa agtgaacttc agcaattatt cccgatgatc
    11761 ttttttacag agactaattc agctgaccgc ttacacgagg ttgacgaaac ttcttacgat
    11821 attatttttt ctactgtacc tctcacactt actgataaga aaaagtctct ctatgttctg
    11881 catccaatca tgactgactt ggaaaaaaat cagctgatca atcaagtaca aagagattgg
    11941 ctgataccag gattttcaat gccttctgcc caagaattgt tgtcggcgct actgccttat
    12001 atcgaattaa aagaaggcgt agacgaagaa aagctctatc aagtattaaa tcgtaaaatg
    12061 aacaaacttt tagaaaagaa ggaggatcaa cgtcctatgc tatctgaatt attaacagaa
    12121 gaaatgatcc aattatcgga tcaaccaaaa aactggcaag aagcaatcac atttgccgca
    12181 cagccgctat tatcagaaaa taaaatagaa gaaagttata tcaaagctat gatcgagcgc
    12241 gtggagcagt atggtgcgtt tatccatatt ggcgatcaca tcgcattacc tcatgctcgt
    12301 ccagaagatg gcgtaaacga agtagggatg tctttgctga aacttcaaca acctgtggat
    12361 ctgcttgata atccagccca tcccattagt ttgttcatct gtttagctgc tatcgataat
    12421 gaggcacatc ttcgggcttt ggcaaattta acaaagctac tttctaataa acaaaatctt
    12481 caagatttat tacacgcatc aacaaaagaa gaaatattag cgatcataag aaaaggagac
    12541 gaatgatatg aaaatttttg cagtatgtca aagtggatta ggaacaagtt ttatggtaga
    12601 gatgaacatc aaacaagcac ttgcagatct tggagcagat gtggacgagt ttgaagtaag
    12661 tcatacggat gttggaagtg tatctagcga tatggctgat tatttcttca ttgagcattc
    12721 tttgaaagat acgctaactt ctatacctga tgaaaagctc gtacctttgc aatcgatcat
    12781 tgacagcgaa gaagtaaaag aaaaagtaac gaagatcttg tcaaaagaat aaaaatgatt
    12841 caagggagga actatcaatg gataaattgt tgaatttgtt tgtgtcaatc gtcagtcagc
    12901 cctccatcct cgtttctttg attgcactgc ttggtctcgt tcttcagaag aagaaatttt
    12961 cagaagtgat ccaaggaact atcaaaacat ttgtcggatt cctagtactg atcggcggtg
    13021 ctggtttaat cagtaattca ctaacccctt ttgcttcgat gttccaaaca gctctgcata
    13081 ctcaaggagt agttcctagc aatgaagcag tagtggcgat tgctttgcaa caatacggta
    13141 cacctactgc tttgatcatg ctagtaggga tgatcgtgaa tattttactt gctagattca
    13201 caagatataa attcattttt cttacaggtc aagcaatgct ttatgtttct tgtctaacag
    13261 cagtcatttt agtaagcgcg gggtttactg caaatttgtg gatgatctta ttaggcgggg
    13321 tcttcgaagg aacactatta actattacgc ctgctctttg tcaaccgttt atgaagaaca
    13381 tcactggaaa caatcaagtt gcgttagggc ataccggaaa tatcggttat gcttctagtg
    13441 gatggatcgg aaagtttttt ggaaacaaag accgttctac agaggacata aagattccta
    13501 aaagtttcag ctttttgcga gattctactg tatcgatcat gctcttgatg tcgatcgtat
    13561 atgtcgcact tgctttgtta gctggtcctg gatttgttga aagagaacta agcaatggag
    13621 acaacgctgt aatctttgca ctgatccaag ctggaacatt cacagctggg tttgttatcg
    13681 tccttcaagg ggttcgaatg gtgttggcag aaatcgttcc agcattccaa gggattgcta
    13741 aaaaactcgt acccgattct aaaccagcat tagatgttcc tatcgttttt ccatatgcac
    13801 ctaatgctgt attaattggc ttttttgtta gcttctttgt aggaacacta tccatgtttg
    13861 ctatgatagg cttgcaaact acagttatca ttcctggggt agtaggacat ttcttctgcg
    13921 gagctgcttc tggtgtcttc ggcaactcga ctggcggtag aagaggggcg gtattaggtt
    13981 ctgctttcaa tagcttattg attagttggc tgccattatt tatccttcca gtattaggag
    14041 atcttaaaat cgcttcttct acatttgccg atactgatta tctagtacca ggacttgtac
    14101 ttgggaaact aggagaatac ggtcaaatag ccttgacagt tggaatcatc gctttctttt
    14161 tacttgtcgt attatctagc tttctttttg ccggaaaaag aacaaacatt gtttctaaag
    14221 aacagaatta agcaaacttc aaaataaaaa ttgcttggac aatatcagaa gaagatttaa
    14281 agtcttctga tatgtcgcaa gcagtttttt gttttatgca tttatttttg aatagcttgt
    14341 taagacaagt ggctgttttg ctagaagagg ataactttta ccattcattt tcactgttcc
    14401 gcctgttcta tcagaagtaa tcacgatctt atcttttgtt ttttcaagcg aaatctttcc
    14461 atctttgata ggtagcgtac aattcagtgt ttcaaatgaa tctagattag gttgtatcat
    14521 aaattcttca taacctggct ttgttggata caaaccgata aaatagcgtc ctaaaagata
    14581 gattgggctt gctccccatg catggcataa gctttttcca taaggatctc catacatact
    14641 gtacttttca tttcctgttt gagtagggtc gtattcttcc cagaaagtta ccgcatcatg
    14701 agataacatc cctccccaat aatcaagaat cgtttggtag acgatattcg tctgtccgag
    14761 tttgcataaa gcatcttgtt catagaattt gaaatatgga gtagtaatct gtgtgatagt
    14821 gtcattcaat aagacattct ttaagatcga ttgctgttgg tctttgttag caaaatcgaa
    14881 taaaacagcg aaaatattcg catgacgcgt cacatttctt ctcccagatt catagcaatc
    14941 gataaaagcg ccaagttctt catcccaaaa gtagtcaaat aggttttgtt tcaatagttg
    15001 atatttttct tgatagagat gagtatgata attttcgttc tctccatatg tttcagctaa
    15061 gatatctccg caagtgatca tggaatgata ggctttcagt aataagactt gttctgcagc
    15121 aagcgttcct tctttatcca tttcagacca atcaataaat atccaatctt ttgctctccc
    15181 ataaataaac cctaattcat tcgtttgctc catcaagtat ctcattaatg attgcatctt
    15241 agggtagacg atgcgtaaaa attcatagtc tttcgtcatc atatagtggt tttcgatacc
    15301 aatcaaccac aagatcgaat agtcaacgat agtattcata tgctgcttga tttcattttg
    15361 tcctcttaat gctaatatcg ttcgtttatt gatttcctcg tcaaaaaaaa gatattgatt
    15421 gatcatgaat gattgatacg catctccaga ccaaatccag cgatctcgtt tgataccgtc
    15481 gataaaaaac aaatcactac ataacttgaa ggcttcttct gatactgacc agatctgatt
    15541 cagtaaagaa gaatcgcttg aaaaagcagc ttgtttcgaa agagataaaa attcatgaaa
    15601 aacttgaagt tgaaccattc cagtagaaac ctctggtata aacaaatagc gaaaagcgcg
    15661 tttacgagct ttcatttttc ttgtcattcc tatttgctta tagtagcaat aatcgatatc
    15721 catagcttct acatcggact ctccataaca tagagtgata gattcgatat ggtcatccag
    15781 agatattagt tctacacagc cattcactgc tcgcccaaaa tcgaataaga ttcctccgcc
    15841 aatctccgtt tcagtgactg gatggacgca ttctttttga taatagattt gatttggatc
    15901 ttttgcgata tcgacataaa gcggactcca gccagctgga tattcttcaa taaaattact
    15961 tgctgtccag ccaatatctg attttacttc gtctccctcg ataaacatcg ctggtagccc
    16021 tgatgtatgt cctacaaaga tacgaatttt tgctttacca gctggacaag tcagccattt
    16081 tccacatgga tgtttttgtc cattaatttc tacataccca actccttgga tcgtcacttt
    16141 aaacatggaa ggttgatcaa gaaagtaata tctcttaaac ttgacgttcc gatggcaatc
    16201 atccatgtac cagtacgctg gccagtcaaa acctcgttct tcccgttgga aattttgtag
    16261 cagtccatgg cggatctcaa agtctccagg ataccaaagc catctatctt tatgtttttc
    16321 atttgtcatt ttacacgacc tccatcaaat ttattttgtt gtcaattgtt cttttatttc
    16381 ttcatctact cttatcactg tctttctatt cgtcctgtgt actactagaa ggctaataag
    16441 cgcgctaatc aacagcaaga tactgccatt gacgaaaaca gcaagtgttt tactcccaag
    16501 agaagcaaaa gagagaaaga gcaaaccata tggtgcaatg aaagtaccta aattagcgcc
    16561 aaccaataag attgaagtat tgaaactctc cgcgtacttg ggcgcttgga tacttacttg
    16621 gttgaataag taaggaatga ataacgaaaa agaaattcct gttaggatcg caccaaaccc
    16681 aatcacatac aggtttatca cagtggcaat caatacaaag ccgattccca tcagtagtaa
    16741 agaaagtgta agcatatagc gatgtgcttt tgtctgaagc cagccaaaac aaactccggc
    16801 agccatactt gccaattgca tgattgttaa gatattcgct gcattagttt cgtttcctag
    16861 agaataagtc gtcaggactg tggctaattt aatcgataca gcattatata ccacgatgac
    16921 cagcaagaga aaaataccat aactaatcat tttaggattc gttttgatta cttgtcttgt
    16981 tggggctgtg ccatgcgatt gaagttcagt tgtttcaggt gtaggaacaa acaaaacaaa
    17041 caagacaaga ataggtaagc tgatggcgta gactaaaaag gtatattgcc aaccgaactg
    17101 tactagctgt cctgcaacaa atgtcattaa agctgcacca aatccttgaa atgcactttg
    17161 aaaaccaatc atagaggctc gttcatctcc gtgataaaag gcagcaatca tgctgactgc
    17221 caaagaattg atcaatccaa agccaatacc tagtccagct cttgaagcta agacaatact
    17281 gtaactttgt gagaagaggg ggaggatacc acaaatcgat gcaatcacta atccgatgat
    17341 cacagtttgt ttttgtccga ttttcctagc aataaaacta ctaatcaaaa caaaaatagt
    17401 gaccataaaa gagggagcag tcgttaataa ttcaacagca gataaagaac gcgtggcata
    17461 agtagctgac atactgggaa ttgcagacgt gactgcacca gcagaagtca aaataagaga
    17521 gactgacagc agagaaaatt tcatcatctt tttattcata agcatgttcc tttcattttt
    17581 gtaagcgctt atcaaaaata tagtatgaag tggttattct ctcaatagcg gaatcacagg
    17641 aagttcatgt cccaaccata gaaagtcttt atgaaaccaa aaatagcttt gcatataata
    17701 gcagtacagc gtgaactaat aagcgaaaga aaccgcttac aaaaaggagg gagtcaattg
    17761 gaactagctg aattagacat tttttttgcg taacgaagaa tcaatcgaaa ctctgcagcg
    17821 tgaacaagga atgaatatca atgatttaaa cttagcttac catcttcaga caccgccaaa
    17881 aatccaccga ggggatctat ttcaacaggg aaatattcat atcagtaaac accgtcgata
    17941 tgcggaagtt cccgagcata cacatgattt tgttgaaatc aattatatgt atagcggtac
    18001 atgtttacaa attattaatg gagaaaggat agagatggaa gaaagtgacg tggtgatcat
    18061 tgataaagaa gctactcaaa gaatcgaata cacagggcaa gaggatattt taatcaacat
    18121 cttattaaaa gaagaaacct tatctacaga gatattgaat catttggcaa gcacaaataa
    18181 tctactttct tcttttttga taaatgcatc aaaagaaaaa ggggaacata cacaattcat
    18241 tcattttcgc ggcggaaaaa caagtcgttt gacgcatttg attgaaaata tgctgttgat
    18301 ttattttgat acatacagtc ataagatccg ttcgttaaat ctctatacat cactattact
    18361 gatcgaattg actcatttat tagaacaaca aagcttttca tcagcagatg gatgcgcaga
    18421 aaatgagatg cttagagtat tagattatat cgataagcat tttacttctt gtacgttaaa
    18481 agaaacagca gctcattttg gctacaatcc ggtctatctt agtaataaat tgaaaatgta
    18541 ttttgatgct tcctttcaag aactggttct aaagaaaaaa ttcgactttg cgttggaact
    18601 gattcaagaa acgagttttt cgttggaaga aatcgctaat cgtatcggat ataaacaaac
    18661 gacttcttta ttcaaattat tcaagaagta ttcaacatgt actcccaatg aatggagaaa
    18721 taaacattaa gaagaaaatc tttcactaaa gcatatgaag gaaaattgtt ttaggtgcga
    18781 ttgctgtctt attatatcgt tgcagcgaat ttttttggat ttattttcag ttctaaactt
    18841 ttggttgtat tatcagggga tataggtgta aacatttgtc atttatctgt tatgcgtatt
    18901 caggaattcg tttccatcaa aaattataat aacaactatt ataattaaca tgttgataaa
    18961 atgaataaac aagactatac ttttcatgaa agtaacaaat agttatgaaa aggagctgtt
    19021 tattcatgaa aaaaacaagt cgtaaagtag taatcgtcgg tacaggtttt gttggaacaa
    19081 gtatcgctta tgcaatgatc aaccaaggaa tctctaatga attagtattg atcgatgtga
    19141 atcaagaaaa agcagaaggg gaagcattgg accttttaga tggtatggct tggggcgatg
    19201 aaaatgtggc tgtatggtca ggtggctatg aagaatgtaa agatgctgat atcgttgtta
    19261 tcacagctgg tatcaaccaa aaacctggtc aatctcgttt agatttagtt aaaacaaatg
    19321 cgtcaatcat gcgccaaatc gtaaaagaaa tcatgggatc aggattcgac ggtattatcg
    19381 ttgttgcttc aaacccagta gatattttga catatatcgc ttggaacgaa tctggtctgc
    19441 caacatcacg tgttatcggt actggaacaa cattggatac aactcgtttc cgtaaagaaa
    19501 tcgcattgaa attaaaagtt gacccacgca gcgtccacgg ctatatctta ggtgaacatg
    19561 gtgattcaga agttgctgca tggtcacata caactgtcgg tggtaaacca gtgtttgaaa
    19621 ttgtagaaaa agaccatcgt attgcccaag atgaattaga tgtgattgct gataaagtcc
    19681 gtaatgctgc ttatgagatc attgatcgta aaaaagcaac ttactatggt attggtatga
    19741 gtactgcacg tatcgtaaaa gctatcttga ataacgaaca agctgtattg cctgtatctg
    19801 cttatttaac tggtgaatac gacgaaaaag atatctttac aggtgtgcca tcaatcgttg
    19861 acgaaaatgg tgttcgtgaa gttgttgaat tatcaatcaa cgaagaagaa aaagcaatgt
    19921 tcagcaaatc aacaagtgct ttaagagaag tattgaacac tgtattataa gaaacaatga
    19981 atatgaacta aaaatcctaa aactgcttaa cagctgaaat agctgttaag cagtttttta
    20041 ttgatatcta ataggtaagc aaataaatag aatggttaaa attaatcggt ccgaaaatgt
    20101 atccgtacat atgaacatat gaaatttaat ctgttgatta caataagcga atcgttatca
    20161 atgtttatct gtggttaatt aaaaaatcct tccgcaacgg caaatacaat gattcatatc
    20221 taattcgttc atatttgatt aactgaataa agaaactggt ttttatcatt caattaaacg
    20281 acaaaaaaag taagaaaaac tgcaaaattt ttttataatt ttgcataagc agattttgat
    20341 ggaaaaatga cgatttttga taaaaaaccg ttcgagagag gtttatcatt ttttaaatct
    20401 actttgtata atatatatta tgtaaactaa aatatataaa aaatcagccc actagttcta
    20461 aaccactatt tcctactatt cactcttttg tattcc
//
LOCUS       DACCVZ010000048        20361 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.048, whole genome shotgun sequence.
ACCESSION   DACCVZ010000048 DACCVZ010000000
VERSION     DACCVZ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.048"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            292..1431
                     /locus_tag="IVW63_001764"
     CDS             292..1431
                     /locus_tag="IVW63_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HAP7860040.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLARHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHSIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1498..2073)
                     /locus_tag="IVW63_001765"
     CDS             complement(1498..2073)
                     /locus_tag="IVW63_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP7860041.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQVGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(2078..3052)
                     /locus_tag="IVW63_001766"
     CDS             complement(2078..3052)
                     /locus_tag="IVW63_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HAP7860042.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPVDIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGLDGLGDTNFPMVLAKQAESL
                     HAVDFLTDYFKEKTDTSVIALGPLTNIASALKNSPSVGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFEKLKQPIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIDESICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(3076..3120)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            3335..4303
                     /locus_tag="IVW63_001767"
     CDS             3335..4303
                     /locus_tag="IVW63_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP7860043.1"
                     /translation="MVIFYFILILIFIGISYHFLSYFYAKKLVRAGVQRGYDWYEETG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGIPKTIKSYDGLKLAGQMFLQPTQQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLIPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPDASIILHGSSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMIMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            4416..4694
                     /locus_tag="IVW63_001768"
     CDS             4416..4694
                     /locus_tag="IVW63_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP7860044.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARREGKKIIPSCPYAKKEFEKKPEYHDVLRQS"
     gene            4812..5048
                     /gene="secG"
                     /locus_tag="IVW63_001769"
     CDS             4812..5048
                     /gene="secG"
                     /locus_tag="IVW63_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAP7860045.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAVWMILLFVLAFLSSK"
     gene            5160..5906
                     /locus_tag="IVW63_001770"
     CDS             5160..5906
                     /locus_tag="IVW63_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP7860046.1"
                     /translation="MKQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFAVRA
                     LEEESVIGGGFFCSPLSPVETNVPENFEKYVRQVLKIAGKSEKEINEKAVSYRSLAEH
                     QLMDIQDQAAIAESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQWYPE
                     SGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            5909..8266
                     /gene="rnr"
                     /locus_tag="IVW63_001771"
     CDS             5909..8266
                     /gene="rnr"
                     /locus_tag="IVW63_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAP7860047.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILVEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSDEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDIVGRRDLRDQLIVTIDGEDA
                     KDLDDAVTVKKLENGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHEIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILEMMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            8288..8752
                     /gene="smpB"
                     /locus_tag="IVW63_001772"
     CDS             8288..8752
                     /gene="smpB"
                     /locus_tag="IVW63_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAP7860048.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            9054..9773
                     /gene="atpB"
                     /locus_tag="IVW63_001773"
     CDS             9054..9773
                     /gene="atpB"
                     /locus_tag="IVW63_001773"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAP7860049.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            9826..10041
                     /gene="atpE"
                     /locus_tag="IVW63_001774"
     CDS             9826..10041
                     /gene="atpE"
                     /locus_tag="IVW63_001774"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAP7860050.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            10132..10656
                     /gene="atpF"
                     /locus_tag="IVW63_001775"
     CDS             10132..10656
                     /gene="atpF"
                     /locus_tag="IVW63_001775"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAP7860051.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            10643..11185
                     /locus_tag="IVW63_001776"
     CDS             10643..11185
                     /locus_tag="IVW63_001776"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAP7860052.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            11208..12764
                     /locus_tag="IVW63_001777"
     CDS             11208..12764
                     /locus_tag="IVW63_001777"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAP7860053.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEETLNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            12778..13680
                     /locus_tag="IVW63_001778"
     CDS             12778..13680
                     /locus_tag="IVW63_001778"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAP7860054.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            13703..15109
                     /gene="atpD"
                     /locus_tag="IVW63_001779"
     CDS             13703..15109
                     /gene="atpD"
                     /locus_tag="IVW63_001779"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAP7860055.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            15123..15545
                     /locus_tag="IVW63_001780"
     CDS             15123..15545
                     /locus_tag="IVW63_001780"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAP7860056.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            16014..16244
                     /locus_tag="IVW63_001781"
     CDS             16014..16244
                     /locus_tag="IVW63_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HAP7860057.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            16341..17642
                     /gene="murA"
                     /locus_tag="IVW63_001782"
     CDS             16341..17642
                     /gene="murA"
                     /locus_tag="IVW63_001782"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAP7860058.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNCPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            17655..17831
                     /locus_tag="IVW63_001783"
     CDS             17655..17831
                     /locus_tag="IVW63_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAP7860059.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            17966..18262
                     /gene="yidD"
                     /locus_tag="IVW63_001784"
     CDS             17966..18262
                     /gene="yidD"
                     /locus_tag="IVW63_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAP7860060.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            18326..18709
                     /locus_tag="IVW63_001785"
     CDS             18326..18709
                     /locus_tag="IVW63_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7860061.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHH"
     gene            18878..19762
                     /locus_tag="IVW63_001786"
     CDS             18878..19762
                     /locus_tag="IVW63_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP7860062.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            19879..20112
                     /locus_tag="IVW63_001787"
     CDS             19879..20112
                     /locus_tag="IVW63_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HAP7860063.1"
                     /translation="MSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGP
                     KEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            20200..20280
                     /locus_tag="IVW63_001788"
     tRNA            20200..20280
                     /locus_tag="IVW63_001788"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20234..20236,aa:Tyr,seq:gta)
     gene            20287..20358
                     /locus_tag="IVW63_001789"
     tRNA            20287..20358
                     /locus_tag="IVW63_001789"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20319..20321,aa:Gln,seq:ttg)
BASE COUNT         6758 a         3566 c         4426 g         5611 t
ORIGIN      
        1 tttttttgca actagcttct gtatatgatg tttacaaaga atggtacaag aaaagatcat
       61 ccttgaaaaa ggaaagctaa caataactag catcatataa gagcttttaa ggatagaaca
      121 gtagaatagg aatctatggg caagtcctct cgtataaata aaataggagg gaagtagcag
      181 catatttttc ataaagtggc tctctttctt catttttact ttggttgctc ctatttgaaa
      241 attcgagcac actcaaatac aataaaaaga aatggcaagg gagaggatta gatgaaaaaa
      301 gaagaaaaaa tcgcgatttt acaagagatt atccgaatta aatcagtgaa tggaaacgaa
      361 ggtgaagtag cagcctattt gaataagctt ttggcaaggc atgacataac aggagagatt
      421 gtttcttaca gagatggtag agataatttg attgctcgtt accaaaaggg ccaatcagga
      481 aaagtgttag gcctatctgg acatatggat gtcgtggcgg ctggtgatga atcgtcttgg
      541 acctatgcac cctttgcagc agaaatccat gggaaccgtt tgtacggacg tggtgctaca
      601 gatatgaaga gtggcttggc agcaatggtg attgccatga tcgaactgaa agagtcagga
      661 aaaccattta acggaacagt caaattatta gccactgtcg gagaagaagt gggtgaacta
      721 ggtggggaac agctcacgaa agcaggctat gtagatgact tagatgcctt gatcatcgga
      781 gagccaacca attacagttt gatgtatacg cacatgggat caatcaacta tacagtcacc
      841 tcgcacggaa aagaagcgca tagctctatg ccagaccaag gttataatgc aatcaatcac
      901 ctaaatgaat tcattacgaa agcaaatgct gaaatgaatc acctcgctga aacaatcgag
      961 aatcctgtcc taggaaaaac aatccataat gttacattga tcagtggcgg gaatcaagtc
     1021 aacagcatcc caagccatgc gcagctccaa gggaacattc gatcgattcc agaataccca
     1081 aatgataaaa tcattgcatt gctgcaatca atcgtcaatg aattgaatca agagacagac
     1141 tatcatttgg aattgatgat cgattacaac aaaatacctg tcaaagctga tccagattct
     1201 cctttgattc attccattca gcaacaattc agccagccat tacctttagt tggagcggca
     1261 gcaacaacgg atgcagccga atttacgaaa gctaaccatt ccttcgactt tgtcgtcttt
     1321 gggcctggtg tcgttacttt gcctcatcaa gtagatgagt atgttgaaat cgataattat
     1381 ttggatatga tcgaaaaata tcaaggaatt attttatcct acttagcgta agattttttt
     1441 aataaatgaa aaaacagagc cagattagca ttattttgct aatccagctc tgtttattca
     1501 gcctattttt ctttttgaat atatcaagcg ttggggcaac atagtgatga ctaatgaaac
     1561 aacgacgata gacaacaagc gatcaaggta gtctgtaccc acctgtacca agatcacact
     1621 tgttgtctga cttaaaccta acccatgtaa tagctgaacg atcatactgg atcctgagga
     1681 ggtgatcccg ccaaataact gaacggtaat gatcgaagaa acgatcgttc caggtaccga
     1741 caaaatcaaa gcgagtaata acagtttcaa gctgttttta tctttgccga gatatcttgg
     1801 caaaatcaat ccagcaagca agcctgtgag aatttggatt ggcgaataat acagagaaaa
     1861 aatatctgta gtcactccac ttaaaatacc gctggacaat cctgtcagca ttccaggtac
     1921 aggcccaagc aatgcaccag caaaaatcgt tccgatagaa tcgagataga ttggcaaacg
     1981 aagccataaa gcaatcgttc ctccaatata attgatccca atacacaaag ccatcactgt
     2041 aagtacgcga gttgccattt tgtttttatt cattttgtta gcccatcttt aacctttcca
     2101 aatctttcat aatcgtttct tcttgtgcat ttaaaagaac ggttaaaaac tttcggaaaa
     2161 aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc caaaattcat
     2221 aacgatcaac caatgtttgt ccgcgactta ttccttgagt ttctacagca gtgaagcttt
     2281 taaagccttc acagatggac tcatcgataa aataagcaac agctaatgga tcattgatga
     2341 cacatcctaa gattctttct tgtttccagt gaaagtcaaa ataaaaacga gtgatcgctt
     2401 ttagatactc tccctcttca ggattcattt ggcagcaata ttcaaggata gtcggtgtca
     2461 agacgatttc tcttgtcaca tctaacccaa ccatttctat cggttgtttg agcttttcga
     2521 atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact ggtgaacagt
     2581 taccatggct tttgtaagtt ccgcccattg agacaaaacg atccatatgt ttcccaacag
     2641 atgggctgtt tttcaaagca gaagcgatat tggtcaaagg ccccaaagca atgactgatg
     2701 tatctgtttt ttctttgaaa taatcagtca gaaaatcaac tgcatggagc gattctgcct
     2761 gtttggctaa gaccatcggg aaatttgtgt cccctaatcc atccaaccca tgagtgtctt
     2821 gcgcactaat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca gggatatcta
     2881 aacgatcaca gcgctccaaa catttcagca cattctgcgt accgatatct acagggacat
     2941 tcccgcaaac gacggtaata gcaactactt cgatatcagg ggatttgaca gctagtgata
     3001 aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tactttacgc attatttcca
     3061 atctcctttc tttagagata cttagttttt tattctggga agtttccgaa ccagtccaag
     3121 acgagtgtct tgtttataat gcacgaaatt agtatactgg cttttattgt gaatgtaaat
     3181 gctctcttac aagtaaatct attgagaaga actttaagta aatgatacaa tgaaaaagaa
     3241 atggaattta cgtgtgccga agaaaaagaa tcctattgat cggtatattg tataataaat
     3301 agattatagt ttggcagaaa gcggcgggtg tacgatggtt attttttatt tcattcttat
     3361 tctgatattt ataggaatca gttaccattt tctttcttat ttttatgcaa agaaattagt
     3421 aagagcgggg gtacagagag gctatgactg gtatgaagaa actgggcacc gcttgatgga
     3481 tcctgctgca gtcacgtcag tagaaaaaaa gcgacaaaaa ttagaagaag agtgtgaaag
     3541 cttctgggaa caaggaatac cgaaaacgat caaaagttat gacgggttga aactagctgg
     3601 acagatgttc ctccaaccaa ctcagcagaa taaatgggtc atttgtgtac atgattatcg
     3661 aagtacaggg aaaagagata tgtctcatat aggtaaaaga tatgcagaga aaggattcaa
     3721 cgttcttata cccgatttac gtgcgcatgg agaaagtgaa ggagaaatca tcggaatggg
     3781 atggctagac cggctagatt taattgcatg gatccaactc atcttagatg aacaaccaga
     3841 tgcatccatt attttgcacg gcagttcgat gggcgcttct actattatga tggcaagtgg
     3901 tgaaaagctt ccatctgcag tcaaaggatt tatcttagac agcggatatg tttctgttta
     3961 tgcggaattt cggtatatgt taagtaaaat cacggtcttt cctaaaaaaa tgatcatgag
     4021 atatgcgaat cactatgctc agaaatacgc aggttattct ttaaagcaag catcagctac
     4081 aagacagctt ggtagtaacc atttgccttt gttagtcatc catggtgaaa gagatcattt
     4141 tgttcctaca gaagcagcat acacgattca aaacgctacg gcaggggata aagcattact
     4201 gcttgttcca gaagcagaac atttggaagc atcgatgaaa gatccgaaaa cctattggac
     4261 agtgattttt tcatttattg aacaaagaat aacgatggat tgattttctc ttcctttttg
     4321 taagcaacac gaggataaat aattgtttat agaccatgag actgttaaaa taaggtagga
     4381 ataaaaaaat atcagttatt tgaggagtgc ggcatatgga aatcaaagag gaaaaaaatc
     4441 gtcttgcttt attcaatgat gagcaacaag aaatcggaga aatgacatgg tcggatgcgg
     4501 ggccagacat catgatcatt gaccatacat ttgtcgatcc agcatatcgt ggtcaaaaat
     4561 tagctgaaaa gctagtgtat actggagtag aactagcaag acgagagggg aaaaagatta
     4621 tcccttcatg cccttacgca aaaaaagagt ttgagaagaa accagagtat catgacgtct
     4681 tacgccaatc ataataataa cagctgaaag atttgcactt tcagctgttt ttccatttat
     4741 atagagttgt cacggagttt tatctatgat aaagttaaag agacgatatc ttttgggaag
     4801 gaggctgcta tatgtataat ttaattttgg gaatcgtgat cgttttatcg attgttatgg
     4861 tcattgcgat tatgatgcag ccaagcaagc aaaatagtgc agcgagtgca tttaccggcg
     4921 gtgcggatca actattcggc aaacaaaaag ctcgcggctt tgaagctgtc atgcagcgat
     4981 caactgcagt catgggagct gtctggatga tcttattatt tgtcctagca tttttatctt
     5041 cgaagtagtc gaataagcct ctcgcacaac ggcgggcggc tttttttatt gcaaagagaa
     5101 cgcttaagaa gaagttatga aagaaactat ggtaaaatga ggcgaaagag gtgaaacgag
     5161 tgaaacaatt accaaaaccc ctttatgcaa aacatggaaa acgagcagtt ttgctgcttc
     5221 atgcgtactc aggaagtcca aatgatgtcc ggatgctcgc acggttttta gaaaaagcag
     5281 attatacagt ctatgcgccg ctatttaaag gacatggaac gatggagcca tatgatatct
     5341 tgcaagaaaa agcagaaagc tggtgggcag atactaaaaa agctatccat tttttacagt
     5401 ctgaacagtt ttctgatatt gccgtattgg gattatcgat gggtggcatc tttgctgtac
     5461 gggcactaga agaagaatca gtaattggcg gcggtttttt ctgttcgccc ctgtctcctg
     5521 tagaaacaaa cgtgcctgaa aattttgaaa aatatgtacg tcaagtgctg aagatagcag
     5581 gcaaatcaga aaaagaaatc aatgaaaaag ctgtgtctta ccgctcgtta gctgaacatc
     5641 aattaatgga tatacaagac caagcagcaa tcgcagaaag tagactatca gatatccaac
     5701 agccaatatt tttagctcaa gctgggaaag atgaaatgat cgacccaaat ggtgtatttg
     5761 aaacggcacg caaattgagc cgccaacgag tgacacttca atggtatcct gaaagcggtc
     5821 atgtgattac agttggcaca gcaagacgcg aattagaaaa agacgtgttg gaatttttag
     5881 aaaaattacc ttggaatgag gaataaatat gacaaaagaa acaataaaag agaaaattct
     5941 ctttttcatg gaaagcagtc gcaaacgtag tttttctatg gaagaaatcg ctgaaggtct
     6001 aggctttcaa aaaagcgatg attttaaatt actagtacaa acgattgctc aaatggaaag
     6061 agaacagagt atcgttttca ataaaaaagg aaaagtcaaa cttcctttaa aaccgatctt
     6121 ggtcgaaggg acatttcggg caaatgaacg aggatttgga tttgtaacga ttgatcccga
     6181 agaagatgat atctatatcc cgaaagaagc gactggcttt gcaatggatg gggataccgt
     6241 agcaattgat atcatgaagc gagcaaatac agatatggat cgcggagcag agggaaaagt
     6301 agtggagatt cgagaccgag cgactactca gttagccgga gaatttgttg cttattcaga
     6361 cgaagagata caggaaacgg atctttatgg tgtggtcatc ccgaaagata gaaagcttaa
     6421 ccaattcaaa gtgtatgcag cggcagaggg agttcgtcca gttgacggaa gtattgtatt
     6481 gatcgaactg acccattacc ctgaaaaagg gtatgcaact agtttagaag ggataatcaa
     6541 gcaagtgatt ggtcataaga atgaccctgg catggatatc ctctcgattg tcgtggctaa
     6601 cggtattcct acaaaatttc ctgatgatgt gttatctgag gcagatgaag ttccagacca
     6661 gatcagcgaa aaggatattg ttggacgcag agatttaaga gatcagctca tcgttacgat
     6721 tgatggagaa gatgcaaaag atctagatga tgcagtgacg gtcaaaaaat tagaaaatgg
     6781 taattatttt cttggagtac acattgcaga tgtatcttac tatgtgacgc aaggcagtca
     6841 actggacaga gaagcatacg aaagaggaac aagtgtctat ttgaccgatc gagtgattcc
     6901 gatgatccca caacgtttat ccaatggtat ctgttcattg aatccccatg ttccacgact
     6961 caccatgagt tgtgaaatgg agatcgatcc aaatggacaa gttgtctctc atgagatttt
     7021 tccaagtgtg atccaaacaa cagaacggat gacctacaca gctgtcaatc aaatcttaga
     7081 agatcaagat gaagaaacga tgcaacgtta tgctcagctc gtgcctatgt tccaagaaat
     7141 gggtgaattg catcgaatcc ttgaaatgat gcgaatcaaa cgtggagcga tttcttttga
     7201 ggatcgtgaa gcgaagatcc ttgttgatgc tgaaggacac ccaaatgata tccagctaag
     7261 aagcagaggg ataggtgaac gcttgatcga atcctttatg cttgctgcca acgaaacggt
     7321 agctgaacat tataataaat taaatcttcc gtttatttat cgaatccatg aacagccaaa
     7381 agaagaaaaa atgcagcgct tctttgattt tgcttcagct ttgggcattc tggtccgagg
     7441 aacgaaagga acgatcacac caaaagattt acagcatgtg atcgaaggag tagaagacaa
     7501 accagaagct gcagttatca atactatgtt gctaagaagc atgcaacaag cacgctattc
     7561 agaagacaat tttgggcatt atggcttagc ggcagattac tacacacact ttacatctcc
     7621 tattcgacgc tatcccgatc taatcgtcca tcgtctgatc cgttcttaca gtgaagataa
     7681 aagtgaaagc aatcaaagtt cgtgggctgc ggaacttcct gaaattgcag atcatagttc
     7741 taagatggaa cgtcgtgcag tagaaacaga acgtgaagta gattccatga agaaagcaga
     7801 attcatgatg gacaaagtgg gagaagaatt cgatgggatc atcagctctg ttgtgaaatt
     7861 cggcctgttt atcgaactgc cgaatacagt agaaggattg atccatatca atgaattgaa
     7921 acaggactac ttccattttg ttgaaaatca tttagctctt gtaggtgaaa gaactggtct
     7981 gacttttaaa atcggacaaa aagtgcgcgt aaaagtagtc aaagctgatc cagatgaacg
     8041 agcagtggat tttgaactcg tttccgcaga agaggtcact gcgttggaac gtccaaaagc
     8101 acgcaatgga aaatctggaa aacgagaagg aaaacaagca ggcaaacgct cagaaaaaaa
     8161 tggcaagaag aacaaacgat atagtgatag taagcaaacg ttcggtaaga aaaaagggaa
     8221 aaagccattt tacaaaggtg tcaaaaagaa gaaaaagaaa aaataaaatg agttggagga
     8281 aacagctatg ccaaaaggcg agggaaaact aattgcacaa aacaagaaag ctcgccatga
     8341 ttattcgatc atcgacacga tggaagcagg gatggtcttg caaggaacgg agatcaagtc
     8401 gatacgaaac agccggatca atctgaaaga tggatttatt cgcgtccgca acggggaagc
     8461 tttcttgcat aatgttcata tcagtcctta tgaacaagga aatattttta atcatgatcc
     8521 gttgcgcacg agaaagttat tattacacaa gaaacaaatc gttcgtcttg aaaacgaatt
     8581 gaaaaacact ggaatcactg ttgttccttt aaaagtctat attcgtaacg gctatgccaa
     8641 ggtattgatt ggtctggcaa aagggaaaaa atcgtatgat aaacgggaag atttgaaacg
     8701 aaaagatatc gatcgacaaa ttgatcgaac attaaaaaat ttctctagat aatttcatta
     8761 tcctttttcg catattcggt gcttttgctt ttacttaatg ataaaatttg ttagcattta
     8821 atctgataaa acatgattat cacaggtttt ttcttagatc aggagcaccg tgcatgggga
     8881 aaaattcgct tcgtttttga ctgaaataaa aaagtgtcta attttcatga aaatgttttg
     8941 aattttctgt ttcatggtgg tatgataccg tgtggttaga aaccgattgg aaaaaaccag
     9001 atacgcacat gaattgattt tatgtgaatt tcggggaaaa gaggtgaaat ggattggatg
     9061 aacgctcgct aacgtttcac attggaccaa tttggtttga tggtacagtt tgtataatgg
     9121 tgttactgac ctgtttgatt gttttcttct tagcttactt ttttacaaga aatcttaagt
     9181 tgaaaccaac aggcaaacaa aatgcgatag aatgggtcat tgattttagt cgaggaatcg
     9241 taacagataa tctgcctaga aaagaattga gcaatttcca tttgttggca tttacattgt
     9301 ttttatttgt ttttgttgca aacaacatag gtttagtaac aaaaatcgtc ttacctaacg
     9361 aaacaacact ttggaaaagc ccgacagcag acccgtttgt tactttaact ttggcattta
     9421 taatgatctt acttactcac ttattcgggg tgaaaaagtt aggcttcaaa ggatatttcg
     9481 taaattcgtt cttgaaaccc tatagtttta tgtttccgat gaaactgatt gaagaattta
     9541 caaacttatt aacacttgct ttacgtcttt atgggaatat ttatgcgggg gaagttttgc
     9601 taaccttgat tgcaaaaatg atgacaagct taggctggtt ctcattacca ttagcaattc
     9661 cattagagat ggtctggatc gcgttctcct tgtttattgg gagcatccaa gcatttgtct
     9721 ttgtcacttt gtcaatggtt tatatgagcc ataagattga agtagaagaa taatactcgg
     9781 ttaaaaaaca aactactatt tatctatttt aggaggaaaa caattatgaa ttatatcgca
     9841 gcagcaatcg caatcatggg agcagcaatc ggagccggtt atggtaacgg tcaagttatc
     9901 tctaaaacaa tcgaatcaat ggctcgccaa cctgaaatgt ctggtcaatt ccgtacaaca
     9961 atgtttatcg gggtagctct agttgaagct gttcctatct taggggtagt tatcgccttg
    10021 attctagttt ttgccgttta attgaatcag tattaaggca gaaacaacat cgtttgttac
    10081 tgctttttta catggaaact agaaatactc caaagaaagg aaggctcgcc tatgctgaat
    10141 caattggcaa ttgcagaagt tggcaatgcg atgttaggta atatcatcgt tgtcagcggc
    10201 tcatttttga tactactggc tctcttgaag cactttgctt ggggaccaat cagcgatatt
    10261 ttgaaaaaac gtgaagacaa gatcgccaat gatttagatt ctgcagaaca atctcgcatc
    10321 aactcagcga aaatggaaca agaacgcgaa caacaattgt tagcctctcg ttctgatgca
    10381 gctgatatca tcaaaaatgc gaaagaaagt ggagaattaa gccgccaaaa tattttgaag
    10441 gatgctcaag aagaagcagc tcgtctaaaa agcaaagccc aagctgatat cactgtagaa
    10501 cgtgattcag cgctgaactc tgtaaaagac gacgttgcag aactctctct tcaaatcgcg
    10561 gaaaaaatct tgaacaaaga attatctcca gaaatgcatg aatcattaat caatcaatac
    10621 attgaaggtc taggttcttc aaatgaaact agataaatat acagtaggaa gacgttacgg
    10681 gaaagcttta tttgaactgg cgatcgattc aaatcaagca gaagaaatct atcaagatct
    10741 cgtaagttta cgtcaaatct atgaacaagt acctggatta gggaatatgt taagtgatgt
    10801 tcgtctagaa cctcatgaaa aacgagaaat catggacaag cttgtcagcg gttatgatgg
    10861 aatcgttaaa aactttttag aagttgttta tgagtataac cgaatggatg accttttgtt
    10921 catgattgaa gaatatgaac gtcgatatga tgaacatcaa gggttactat tgggaagtgt
    10981 cacaacagca gtcccacttt cagacgaaca acgaatacaa ttagaaaaga atgttgcaaa
    11041 aacaatggac tatcaatcag ttgaattaaa acaaatcgtt gattcttcta ttattggtgg
    11101 cgcgattgtt gaagccaacc atcgagtaat cgacggaagc attcgcacgc aattagaaaa
    11161 aatgcgtaat caattaaaca gatagtacaa agaggtaggt gaatcgaatg gccatcaaag
    11221 cagaagaaat tagtgccttg attaaagaac aaattgaaaa ttatcaaaac gtgctttcag
    11281 tcgaagaaat cggtaccgta acttatgtag gtgacgggat cgctcgtgca catggtttag
    11341 aaaacgcgat gagtggtgag ttgcttgaat tttcaaacgg ctcatacgga atggcgcaaa
    11401 acttagagtc aaatgatgta ggtatcatta tccttggcga tttcgagtcc attcgtgaag
    11461 gagataaagt aaaacgaaca ggtaagatca tggaagttcc agttggagag gccttgatcg
    11521 gtcgggtagt caatccgcta ggtcaaccaa tcgacggact aggtgaaatc gttactgaca
    11581 aagctcgtcc agtagaagcg atggcaccag gtgttatgca acgtaaatct gttaacgaac
    11641 caatgcaaac agggctaaaa gcgatcgacg cccttgtgcc aatcggacgc ggacaacgtg
    11701 aattagtcat cggtgaccgt aaaacaggga aaacttctat tgcgattgat acgatcatca
    11761 accaaaaagg tcaagatatg atctgtatct atgtagcaat cggacaaaaa gattctacag
    11821 ttcgtacaca agttgaaaca ttgaaaaaat atggcgcaat ggattacaca atcgttgtga
    11881 atgccggtgc gtctcaacca gcaccattac tttatatcgc accatatgct ggtactgcaa
    11941 tgggtgaaga attcatgtac aacggtaaac atgtattgat catttttgat gatctttcaa
    12001 aacaagctgt tgcttatcgt gaactttcct tgctacttcg ccgtccacca ggtcgtgaag
    12061 cttatcctgg ggatgttttc tacttgcact cacgtttatt agaacgtgca gcaaaattaa
    12121 gtgatgatct aggcggcggt tcaatgactg ctttgccatt tgttgaaaca caagctggag
    12181 atatctctgc ttatatccca acaaacgtta tctcaatcac tgacggacaa atcttcttag
    12241 aaagcgactt gttctacgcg ggtactcgtc cagcggttga tgccggacta tctgtctctc
    12301 gtgtaggggg ttctgcgcaa atcaaagcaa tgaaaaaagt tgctgggact ttacgtctag
    12361 acttagcaag ttatcgtgaa ttagaagcat ttacacaatt cggttctgat ttggatgcgg
    12421 caacacaagc aaaactaaat cgtggacgcc gtacagtaga aatcttgaaa caaaaactgc
    12481 atgcaccgct agctgttgag aaacaagtag tgattttgta tgccttgaca catggattct
    12541 tggacagtat ccctgtagac agtattttag acttcgaaca tgaattattc gaatatctgg
    12601 ataccaatca ttcagatatt tttgaaacaa tccgtacaac aaaagatctt ccagaagaag
    12661 aaacgttgaa cagtgcgatt caggaatata aagacatgtt cttagctaca aaaggaaata
    12721 attcctctac agaagataaa ttgaaatcca ttcaaaatgc atagtgaggt gagatgaatg
    12781 ggtgcttcat taaatgaaat caagacacgt atcgcttcaa cgaaaaaaac gagccaaatc
    12841 acgcgggcaa tgcagatggt gtctgcttct aagttgacaa aatctgaagc ttcttcacag
    12901 aagtttcagg tttatgcaac aaaagtaaga gaaatcgtta cgcatttgac tgctactcag
    12961 ttaaatgata ttgcctcaga aaatcctaga ggggatatca attacaacag catgctgctc
    13021 agccgtcctg tgaagaaaac cggttatatc gtcatcactg cagatggcgg tctggtcggt
    13081 ggatataaca gttcgatatt gaaacaaacg atgtctattt tagaagaaga ccaccaatca
    13141 cccgatgatt acgtgatgat cgcaattggc ggaactggtg cagacttctt taaagcacgc
    13201 ggtatcaacc tagcatatga gctgcgcaat ttatctgatc agccaagctt tgatgaagtc
    13261 cgcaaaatcg taaatatggc aacaactatg taccaaaacg aagtattcga tgaattatac
    13321 gtatgttata accatcatat caattcgcta actagtcagt ttcgtgtaga aaaaatgctg
    13381 ccaatctcag acttagatcc agaagaagca acgactttcg aacaagaata tatttttgaa
    13441 ccttcaaaag aagaaatctt gtctcagtta ttgcctcagt atgctgaaag tttgatctac
    13501 ggtgcgatcg ttgacgccaa aacagcagaa catgctgctg gtatgacagc aatgaaaaca
    13561 gcaactgata atgctgctaa tatcattgat gagctgacgg tttcttataa ccgtgcaaga
    13621 caaggggcta ttacccaaga aattaccgaa attgttgccg gagcttcggc actagaatag
    13681 tattgagatt ggaggaaaaa agatgagttc aggcaagatt gttcaagtaa tcggtcccgt
    13741 tgtcgacgtg gaattttctt tagaccaatc cttaccagat atcaacaacg cattagttgt
    13801 ttataaaaat gacgaaaata aatcaaaagt tgttcttgaa gcagcgttag aattagggga
    13861 cggagtgatc cggaccattg cgatggaatc aacagatggt ttacaaagag gaatggaagt
    13921 cattgataca ggcaaagcaa tctctgttcc tgtaggtaaa gaaacattag gtcgcgtatt
    13981 caacgtacta ggagatacga tcgatttaga aacacctttc ccagaagatg cggaaagaag
    14041 cgaaattcat aaaaaagcac cagcctttga cgaattaagt acaagtacag aaattttgga
    14101 aacagggatc aaagttatcg atttgcttgc cccatattta aaaggtggga aagtcggact
    14161 attcggtggt gccggtgttg gtaaaaccgt actgatccaa gaactgatcc ataatatcgc
    14221 ccaagaacat ggtggtattt ctgtatttac cggtgtaggt gaacgtactc gtgaaggtaa
    14281 tgacttgtat tatgaaatga aagattcagg agttatcgaa aaaacagcca tggtgttcgg
    14341 acaaatgaac gaaccaccag gtgcacgtat gcgtgttgct ttgactggtt tgacgattgc
    14401 ggaatatttc cgtgatgtag aaggtcaaga tgtactgttg tttatcgaca acattttccg
    14461 tttcactcaa gctggatctg aagtatcagc cttgttagga cggatgcctt ctgcggttgg
    14521 ttatcaacca acattggcaa cagaaatggg tcaattgcaa gaacgtatca catctacgaa
    14581 aaaaggttcg atcacatcga tccaagcaat ctatgtgcca gccgatgact acactgaccc
    14641 ggcgccggca acagcattcg cccatttgga tgcgacaacc aacttggaac gtaaattaac
    14701 agaacaaggg atttatccag cggtagatcc attggcttct tcttcaagtg ctttagcacc
    14761 tgaaatcgtg ggagaagaac attataaagt agcaacagaa gtccaacacg tattgcaacg
    14821 atatcgtgaa ttacaagata tcattgctat cttaggtatg gatgaattat ccgatcaaga
    14881 aaaagtgtta gtttctcgtg cccgcagagt ccaattcttc ttgtcacaaa actttaacgt
    14941 ggctgaacaa tttactggtc ttccaggttc atatgtccct gtagaagaaa cagtgaaagg
    15001 attccgcgaa atcttggaag gcaaatacga tgatcttcct gaagaagctt tccgaagtgt
    15061 tggccgaatc gaagacgtcg tagaaaaagc gaaaacacta ggctactaga aaggggtgcc
    15121 ccatggatca atatttaaca gtaaatgtgg taactcctgc cggtttggtc tatgatcacc
    15181 atgcagctat cgtcgttgca cgtacgacag ctggtgagct tgggattttg cctaaacatg
    15241 caccaatcat cgttccattg acgattgatg aagttcgtgt aaaacgaaca gattcagata
    15301 cccacgtcga ttggatcgct gttaatggcg gaatcatgga agttcgtgat aatgttgttt
    15361 caatcgttgc tgatagtgcg gaacgtgaac gtgatatcga tgtatctcgt gcggaacgtg
    15421 caaaacaacg cgcagaacgc caaatcgaag aagcaaaagc aaaacaagat acgaacgaat
    15481 tgaaacgggc aactgttgcg ttgcaccgag caatcaatcg tatcaaagta tctaagcact
    15541 cataaaatga gatgcggatg tttatccgtg tttaagaaca gtaaaaagag gttatgacag
    15601 aagtggtcag cttcaagaca taagaaggaa tttacgaaaa ttgcttctca aatttttgtg
    15661 aaatctcagc ttatttttcg aagaagctac ttctggaaca ccgtatatca gaggttgtga
    15721 aatcagcgtt ttgtcctgag tattagagaa acaaatggaa aatagttcct catattttgc
    15781 cgttttttga gctaataccg agggtcagat gattgaacac cgtttatttg gaataaggga
    15841 ctgcgacaag acttttgtct cagtcccttt ttttgcatat ttttagcatt tatttcctaa
    15901 aaaatgtaag gggattccta tatttttaag tatacttgtt tttcctttta tacattttat
    15961 ggtattatca ttttattagt tattataaaa caatcgttag aaaggacgtc attatgcaag
    16021 tatacggaat tgatgcggtg cttcgaatcg tgagtcattt ggcgtttatc tacttagcct
    16081 tctggtcttt acgttcgtta cgcattgaaa cttttttcag accaatgcat aatacgcaaa
    16141 ttagaatggc aatcgtactt ttttcaattt ttttagggta cactgcaagt aattttttct
    16201 tagaagttat cgctttatgc cgaaatcttt tcgttagcct gtaaatttta aaaaaaggta
    16261 ctattttaaa agcaaggatg ttataataga aaagattttg agtaagtgta tgctcattgg
    16321 aattttttgg agggaacaac atggaagaga tcatcgtaag aggtggcaat caattaaatg
    16381 gaacagtaag aattgaagga gctaaaaatg ctgttttgcc tattttagct gctagtttgt
    16441 tagcagaaga aggtattacg acattagaca acgttccgat tctttctgat gtcttcacta
    16501 tgaatcaagt gattcgtcac ttaaacgtag atgtagattt tgatgaacaa aagaatcaag
    16561 taacaatcga cgcttcaaga caattagaaa tcgaagcgcc ttatgagtat gttagtcaaa
    16621 tgcgtgcttc aatcgttgtg atgggtccgc tacttgccag aaatggacat gcaaaagtag
    16681 ctatgcctgg tggatgtgcg attggtaaac gaccaatcga tttgcattta aaaggatttc
    16741 aagctttagg agcaaaaatt attcaaaaaa acggctatat cgaagcaatt gcggatgaat
    16801 tgatcggtaa cacgatttat ttagatttcc ctagtgtggg tgctactcaa aatatcatga
    16861 tggctgccgt aaaagcaaaa ggaacaacca tcattgaaaa cgtagctcgc gaaccagaaa
    16921 tcgttgattt agcaaacatt ttgaataaaa tgggcgctca agtctatgga gctggtactg
    16981 aaacaatgcg tattgaaggc gtggatcatt tacatgcagt caaccactca atcgtacaag
    17041 atcgtatcga agcaggtacc tttatggttg ctgctgcaat gacacaaggc aatgtgctga
    17101 ttgcagatgc tatctctgaa cataactgcc cattgatttc taaattgatc gaaatgggtg
    17161 cagaaatcat tgaagaagaa ggcggagtcc gtgtcatcgg accaaaacat atcttaccta
    17221 cagatgtaaa aacgatgcct catcctggtt tccctacaga tatgcaagct caaatgacag
    17281 ctatccaatt agttgcagaa ggtacaagtg tggtgactga aacagtgttt gaaaatcgtt
    17341 tccaacattt agaagagatg cgccgtatga acgctcatgt caaaatcgac ggaaatgtag
    17401 caatcatgga tggaaaccat gaattgcaag gtgcagaagt atatgcaaca gacttgcggg
    17461 cagcagcagc attagtttta gctggcttga aagcaaatgg aatcacacgt gtgcgtaact
    17521 tgaattatct agaccgtgga tattataatt tccatatcaa actacagcaa ttaggtgcag
    17581 acgtcgaacg tgtagacatg gatcaaactt ctgctgaaaa aacagcacaa acgattgctt
    17641 aaggaagtgg ctgaatgagt aaccaacgat atatcttatt aactttgata aagattttag
    17701 tggtgatctt attgcttatc cttctttttg tggccggaac gatgatcgga tatggtgtca
    17761 tcggtggcgg caatccattt aaagtattcc agccaagttt gtggattcat attcgagact
    17821 tttttcattg ataaataaga atcacagtgg ttctagtcga tatgaagtga gccatgaagc
    17881 agaacatgat aaaagaaaac agaagggaac gttgacgtta gtcgcgatcc ctttttttag
    17941 taaaagaaaa gaaggaatct aattgatgaa gaagatattg atttatttag ttagaggata
    18001 tcagcgcttt atttcgcctg catttccacc tagctgccgt tattacccaa cctgttccaa
    18061 ttatatgata aaagcaattc aaacccatgg tgcgctaaaa gggacggtaa tggggactgc
    18121 acggatctta cgctgtcatc cttttgtcaa aggcggtatc gattatgtac cattgacatt
    18181 ccgattaacg cgaaataaga aagataaaaa agaaccagat tataaaaagg ttgtgaaaaa
    18241 tacgggtagc actgagcgat aaagaaaaag aggaaattta ttgtcaaagt aacaactccg
    18301 caactactta tatgggggac aaaaaatgat cgaagaacta aacaagaaag atttaccatg
    18361 gtccttgtta ttagatgcag atcctgataa agaaaaagtt caagtatatg tttccagagg
    18421 gagtggctgg atatggaaag aaaaagaaaa aacaataggt gtactgatct atgtggcaag
    18481 ggaaaaagaa tacgaaatcg tcaatgtagc agtaacccca acgtatcaag gaaaggggat
    18541 tggcggaaaa ttacttgaga cagcttttca gaagctttca cagctagctt caaaccaaac
    18601 tcggatcatt atacgtactg gcactactag tagcgctgcg ttacacctct atcaaaaaat
    18661 gggctatgtg gagattggtc gagtcaaaga ctattttatc catcattaat ctgagcccat
    18721 ttttgaaaat ggagatcaat taagggatca agtgatttta gcaattcact tacctaaaaa
    18781 tagctttaac taataaactt tcaattcgag aaaatgcttt caaatgctaa atagatacat
    18841 tacaatagct ttagcaaaca aaaaggagaa tatttttatg ggaatattag tttttgattt
    18901 tggtggatcg gctgtcaaat atggttgttg ggatggcaaa gagattaaag gtaagggaca
    18961 atttgcaacg cctgaatctt gggaagaaat gaaaacgcaa ttatttcaag tttataaaaa
    19021 aatactcgtt tcttttgaag tcgaaggaat tggaatcagc tctcctggag tagtgaataa
    19081 tgagaaacag gtgattgagg gaatcagtgc gattccttat attcatggat ttaatatttt
    19141 ccgagatttg gaaactctgt ttcaactccc agtaacgatt gaaaatgacg ccaactgtgc
    19201 cggaatggct gaattttatg aaggtgctgc ccgtgattat caagatgttg cttttgttgt
    19261 ggcaggaact gggattggcg gggcgttgtt cacgaaagga caaataaata aaggggcaca
    19321 tctttacggt ggagaatttg ggttgatgtt cttagatggc gataagacat tcagtaaact
    19381 tggtacagcg gtacagatgg cttggcgtta ttgtgaacgc aaaggtctcg ataaaaatgc
    19441 ttataccgga aaagatgtct ttgaattagc agaaactgga gatgcaatag caaaagaaga
    19501 agttgagagt ttttatacgt atcttacaaa gggattattc agtattcaat tttcgtttga
    19561 tccagaagtg atcgtattag gcggcggggt ttctgcaaaa gaagggctca ttgatgagat
    19621 caaaagccga atgaagaagc tgacagaaca attcgatctg catgatttcg aaccgcagat
    19681 tttattatgt gagtacagaa acgatgctaa tcttgtaggt gcagcagcaa actatctcgc
    19741 tgtacgtcaa ggagagaatt aagagcttta gagaaggtgc agcttgcata aaagaagaga
    19801 atgaaatgaa taggagattt ttacctaagg aatgttttat ttgctgcagt atgataaaat
    19861 atctgagagg tgaaaatgat gtcaaaaaaa aataaagata ttgaagtgcg tatagaagaa
    19921 gtgaaaaaag atatcaaagg taagaattat gaagtcactc agttatttat agggaaaaaa
    19981 atgattggtg agatcttagc ctatgggcca aaagaatatg aaattttctt tggtgaagaa
    20041 gattttggaa aagaaaaaag tcttgaaaat gcgatagaaa cagtgattcg acactggaat
    20101 ctgcacgaat aaaaaaatat caaaaaaact ttcaataaag ggttgcaaaa atctggaaga
    20161 ttaggtatta taactaagtc aggttgatac aaacctttcg gaggagtagc gaagtggcta
    20221 aacgcgacgg actgtaaatc cgttccttag ggttcagtgg ttcgaatcca ctctcctcca
    20281 tttcattggg gtatagccaa gcggtaaggc aagggacttt gactccctca tgcgttggtt
    20341 cgaatccagc taccccagta t
//
LOCUS       DACCVZ010000049        20286 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.049, whole genome shotgun sequence.
ACCESSION   DACCVZ010000049 DACCVZ010000000
VERSION     DACCVZ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.049"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            141..461
                     /locus_tag="IVW63_001790"
     CDS             141..461
                     /locus_tag="IVW63_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860064.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            913..1113
                     /locus_tag="IVW63_001791"
     CDS             913..1113
                     /locus_tag="IVW63_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP7860065.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1260..4049
                     /locus_tag="IVW63_001792"
     CDS             1260..4049
                     /locus_tag="IVW63_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP7860066.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4096..4623
                     /locus_tag="IVW63_001793"
     CDS             4096..4623
                     /locus_tag="IVW63_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP7860067.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4644..5834
                     /locus_tag="IVW63_001794"
     CDS             4644..5834
                     /locus_tag="IVW63_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP7860068.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5874..7172
                     /gene="asnS"
                     /locus_tag="IVW63_001795"
     CDS             5874..7172
                     /gene="asnS"
                     /locus_tag="IVW63_001795"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAP7860069.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            8225..8899
                     /locus_tag="IVW63_001796"
     CDS             8225..8899
                     /locus_tag="IVW63_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP7860070.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            8896..9237
                     /locus_tag="IVW63_001797"
     CDS             8896..9237
                     /locus_tag="IVW63_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860071.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            9267..9626
                     /locus_tag="IVW63_001798"
     CDS             9267..9626
                     /locus_tag="IVW63_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAP7860072.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            10150..12231
                     /gene="cadA"
                     /locus_tag="IVW63_001799"
     CDS             10150..12231
                     /gene="cadA"
                     /locus_tag="IVW63_001799"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAP7860073.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            12542..14008
                     /locus_tag="IVW63_001800"
     CDS             12542..14008
                     /locus_tag="IVW63_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7860074.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            14623..15162
                     /locus_tag="IVW63_001801"
     CDS             14623..15162
                     /locus_tag="IVW63_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HAP7860075.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            15236..15676
                     /locus_tag="IVW63_001802"
     CDS             15236..15676
                     /locus_tag="IVW63_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HAP7860076.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            15689..15898
                     /gene="copZ"
                     /locus_tag="IVW63_001803"
     CDS             15689..15898
                     /gene="copZ"
                     /locus_tag="IVW63_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HAP7860077.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            15898..18084
                     /locus_tag="IVW63_001804"
     CDS             15898..18084
                     /locus_tag="IVW63_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAP7860078.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            18104..20275
                     /gene="copB"
                     /locus_tag="IVW63_001805"
     CDS             18104..20275
                     /gene="copB"
                     /locus_tag="IVW63_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HAP7860079.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         6778 a         3527 c         4407 g         5574 t
ORIGIN      
        1 aaaaaagagg ttgtgacgtg gtcacgacct ctttttgacg attatgatac aaaaaacatc
       61 atttatgaac aaaatgtgaa taacgggcgt tcttgagata tgattttaat tgggaaaaac
      121 ttatcgataa ggaggtcttt atgaaaaaaa gactgttatg gtgtttgctg tttctatccc
      181 taagtttaac aagtcagcca gtttttgctg aagaaacaca gcggtctcct attacaggca
      241 cacgtctgta caaaaatgtt tatgtacaga caacagatct tgattctgcg attcctgaaa
      301 cagaagaacg gtctttgcag ccaagatttg gttacttttg gtactgtccg acctgtgatt
      361 atgaaagttg ctggcatttc ttacattcta cagctgcagc ttttgctttt actcatactc
      421 agaaatatga tggacatcat cctgttattt atgaggtata gatatgagca aaaaagaaaa
      481 actaatctcg ttgatcgtat tggtttgcct tgttcttctg gtaactgtca taggctatca
      541 gaaataccat gagaacatca gacctactaa agaatcttcc ccagcctcga ccgttgaaac
      601 agaaccgata agtagtcaga aagaataatt tttttagttt aaagaagaac atcagagcaa
      661 aaaaacacca actgaacaat atgtcgttta ttttaaaaaa agttcggttt ttcactttat
      721 gtaatcgctg agaaaacttt ttttaataaa aaaagtcgaa aaactctagc ttttttgtaa
      781 acggtatgat atactatagg agtagttttt gttcggtaat ctgtggtagc ttgtttcaaa
      841 taaacatctt ccagatatac accattcaag taattgcaaa atatgtgttg atacacaagg
      901 aggattttta ttatggaaac aggtacagta aaatggttta actcagaaaa aggatttgga
      961 ttcatcactg cagaaaacgg aaacgatgta ttcgttcatt tctcagctat ccaaggcgac
     1021 ggattcaaaa ctttagaaga aggccaagca gtaactttcg atgttgaaga aggccaacgc
     1081 ggacctcaag caacaaacgt tactaaagct taattaacct atactaaaaa ataaacgccc
     1141 agacatttgc gtgtctgggc gtttttgtct attttcttta aaaagcgatg agagtatttt
     1201 tctgcacttt gtagtataat ttcaaaagaa cattagaggc aggagaagag gaagatattt
     1261 tgaaaccaag aacttatgca gtcgttgata tcgaaacgac tgggacgaat ccaaaagaag
     1321 atcggatcat ccaatttggc tgcgtcatga ttgaatcagg tcggatcact tcacgttttt
     1381 cgatcgatat tcatccaggg cggaagattt caaaacaaat ccagcattta acagggatca
     1441 cgaatcaacg cgtccaaaaa gcgccttatt tcgaagatgt cgcccaaacg atttacaatc
     1501 ttttggcaga caccatattt gtcgcgcata atatttattt tgattataat tttttgaacc
     1561 atgaactcat gcgatgcgga cttcctagtt tgaagatacc aggcatcgat acagtagaac
     1621 ttgcacaaat tttcttgccg acggaaccaa gctttcgctt agctgatttg tcagaaagcc
     1681 ttggatttat tcatgagaat cctcatcagg cagatagtga tgccgaagtg acgggtcaac
     1741 ttcttttgct gatcgaagaa cggatgagaa aattgccaat catcacgtta gagcagattg
     1801 cgcgattaag tagacacaca ggtatggata cgagtcgttt catttatcat gtgattgaag
     1861 aaatgaaaga aaaaccagag ccacttgatc cctcattaga aatcgtcgat gggctagctt
     1921 tgcagaaaaa agaagtggaa ctattcacat ccgtccatta tggcgagcgg acatatccaa
     1981 gaaaaaaaca agcaaaagaa aaaatgtttg gtaaaacact gatgtatcga aaagaacaga
     2041 acagactgat gaatgcggtc tacgaccatt tcacaaaaga tgaatcaaaa gatttgatga
     2101 tcgaagcagc tacaggaatg ggtaaaacaa tcggttatct gctgccattg agttatttgg
     2161 ctacacctga aaaacccgct gtcatcagta ccgtttcgct agttttgcag cagcagatca
     2221 tagaaaaaga cattccattg ctgaatcaat tgctagatca gcccatacaa cctgtaatta
     2281 tcaaaagcta tcgccactat attgatttac agcgttttaa aggcacactt gtggaaccgc
     2341 cagaacaaaa acaatatgct ttgtatcaaa tggcggtctt agtttggctg acgcaaacga
     2401 agaccggtga tttggatgaa ttacatttaa caaatttgaa ccattcattc tttgcagata
     2461 tcgcgcacag aggtattgga tttttagcaa gaaatcagtc attttacgaa caagactttg
     2521 ttcgtttctt gcaaaagaaa atcaggcaaa gtaatttttt gattgtcaat catgcgtttt
     2581 taatacaaga aacacagcga aaagaaccat tgcttccagc tagtccattt ttgttgatcg
     2641 atgaagtaca tcatttgccg gaaatcgctg aaaaagtaaa tgacaaacga ttaagtatta
     2701 actatttcca taaacaaatc cagcaattag aagaaccaaa tcagctgttt gaccgaatac
     2761 aaagctattt accgaaagaa catgaagcct tacgctggtt atcgatttat cgagaagaac
     2821 tttctgcgct atgcgaagca cagatttgta tggcagaagg attaatgagt ttagtgagcg
     2881 gcaagcaacc taacggacag tatccagaag aagtcatgat gacaaaagag atgttggatc
     2941 agctgccact ggaatctggg acagccattg atcacctgca gcttttttat caggagatcc
     3001 agcagctaca gtcacaaatg cgtctgactt ttgagattat ccaagaaagc tggacaaacc
     3061 agatgcggat cgatttagca agtttatata gcttatttga tcaattagac aagcagtact
     3121 tgctgatgga tcaatggctg gaagactggc gagatcattt gatccattgg ttcgttcctg
     3181 ggaacacagc gcagcagatg atttttcatc tccatgattt tcaagcggct atgttgccgt
     3241 cgactgtttg gtatcctcga tatgatcgta ttctttatat tggaggaacg ctgaagatcg
     3301 gccctaatcg acactatctc tctaagcggc ttggcattga agcagcacct cttaaagtga
     3361 ttgcctctcc ttatgattat gagaaacagg caaggatcta tgtgccaaaa gaggcacctg
     3421 ccgtccatca agtcagcaat caagcatata tcgattattt agagacagca cttacaggtc
     3481 tgatcgaaca agaagatcgg ccaatacttg tgttattcac ttctcatgat gttttgcaga
     3541 aggtctatca gaaaatgcat ctgtctatgc tagaaaaagg acgagaaata ctagctcaag
     3601 ggtttggcgg aagccgggag aagcttttga aacgcttcat tttgtcagaa aaaagcgtat
     3661 tgtttggcgc tgacagcttt tgggaaggtg tagatttgcc tggggatgct ttgcagatcg
     3721 ttgtagtcac acgtttaccc ttcgataatc cgcttcgccc gatggtcaaa gctaggaacg
     3781 cttatttaga atcagagggg atcaatcctt tttaccagga atccgtacct aaagcagctt
     3841 tgaagttacg ccaagcatta ggtcgcttga taaggacgga gacagatcgt ggcgtattgc
     3901 ttattttgga tcgaagacta gtcactgcaa aatatggtgc acggatcatc catgcattac
     3961 cgaaaaaagt accgatcaaa gagctagcta tggaggaaat ctatcaggac atccatgaat
     4021 tcttaaagaa aaatgaagaa ggaagttaga ggagctgtct tttttcataa ttaaaatctg
     4081 ctataatgaa aaggaatgaa gataaaggag cgacgaccct tgaagaaaaa acagacaaag
     4141 gaaaaaacga ttaatcgcgt gttacttggc ttgatcgtat ttttattagc ggtcatcgtg
     4201 atcagctcga ttttttactt gcgttccagt cgtccggcgg tgcaggcgaa gaaagaagca
     4261 gtagaaatcg caaagaaata tgcaaatctt gaggaagccg atcattttta ttggtttact
     4321 cgaaagaaga catacttttc actgacaggt acaaatgata aaggaaaaga aatcgccgtt
     4381 atcattccta aatctggtga aaaagtaaaa gtattggatc aaacaaaggg actgactgaa
     4441 aacgaagcaa aacagacaat tgctgcggcc catcctgaaa tccaaatcga aaaagctgct
     4501 ttagggatgt atgatgatca gcctgtgtgg gaagtagtag gaaaagaaac aaatgggaaa
     4561 ctgaattatt acctgattgg ctttgaatct ggagatgaag tcaagacaat caagggaatt
     4621 taaaaggtaa aggaatgaat gggatggagt tatcaaaaag aacaaaacga ttagaaccgt
     4681 ctgtcacttt ggcagctgcg gcaaaggcca aggcattaaa agcaaaaggc agagatgtgc
     4741 tgagtttgac tgtgggagaa ccggattttg cgacaccaga aaacatccaa gaagcagcaa
     4801 tcgaagcaat ccgcaacggg aaagctagct attatacacc aacagcagga atcccagagc
     4861 ttcgacaggc aatcgttgat tatctgaaga aaaactatgg acttgtctat gaaccttcac
     4921 aaacagtcgt aacagacgga gcgaaatttg ctttgtatac ccttttccaa acgatccttg
     4981 acccgcaaga tgaagtcatc attcctgtgc cttactgggt cagttacggt gagcaagtaa
     5041 aactggcaga aggacttcct gtctttgtga aaggggaaga atccaatagc tggaaagtta
     5101 ctgttgaaca gctagaacaa gcacgttcag aaaaaacaaa agccgtaatc atcaattctc
     5161 catcgaatcc gactggaatg atttatagca agaatgaact gcaggcaatc ggtgaatggg
     5221 cagtaaaaaa tgatattttg atagttgctg atgatattta tggtcgttta gtttataatg
     5281 gcaatgagtt tactccaatt gcaacgattt cagaagcaat caaaaatcag actatcatca
     5341 tcaacggcgt gtctaaaaca tatgcgatga caggctggcg cattggttat gcggtgggaa
     5401 atcctgtgat catcaatgga atgatcgctg ttgcttccca gtcaaccagt aatccgacag
     5461 cagtcagtca atatgcagct gttgaagcat tgaaaggcga gcaagataca gtggaagaaa
     5521 tgcggaacgc ctttgaagaa cgcctgaata cgttatattc gcttgtggca gaactgccgg
     5581 gtgtttctct tgaaaagcca caaggagctt tttatctttt tcctaatgta aaagaaacgc
     5641 tacgcatgtg taaatatgaa aatgtcacac aatgggtaga agatctttta gaagaaacag
     5701 gggtagcgct tgtgactggc gaaggctttg gggcaccaga aaatgtccgc atgagttatg
     5761 ctactgatcg cgctacgtta gaagaagcgg tacgcagaat caagcaattt attgagagta
     5821 aaagtcaaaa ttaatcctaa agaaattcaa ggaatataaa aggagagtca tacgtggaac
     5881 aaattcaaat catcgattcg aaaaaccatg tgggagaaac agtaacaatc ggcgcttggg
     5941 tcgcaaataa gcgatcaagc ggaaaaatcg catttttaca attaagagac ggaacagcct
     6001 ttttccaagg tgtagttgta aaaagcgaag tgtcggaaga agttttccaa acagctaaaa
     6061 atctacacca agaaacatcc gtgttagtaa ctggagaaat ccgtgaagac agtcgttcaa
     6121 aatttggtta tgaaatcgga attacaaatg tggaagtggt aagcgagagc cacgattatc
     6181 cgatcacacc aaaagaacac ggaacagact tcttgatgga tcatcgtcat ttatggctgc
     6241 gttcttcaag acaacatgcg attatgcaga tcagaaatga aatcattcgt gcaacgtatg
     6301 aattctttaa tcaacatcat tttgtcaaaa ttgatccgcc gatcttgact ggttctgcac
     6361 cagaaggcac tacggatcta ttcgaaacaa attactttga tcaaaaagct tatttatctc
     6421 aaagtggcca attatacatg gaagctgctg ctatggcttt cggaaaagtc ttttcattcg
     6481 gtccgacttt ccgtgctgaa aaatcaaaaa cacgacgtca tttgatcgaa ttctggatga
     6541 tcgaaccaga aatggctttc actcatcaag aagaaagttt agaagtacag gaacaatatg
     6601 tagcattctt agtacaaaat gttttagatc attgcgaata tgcattagat gtactaggac
     6661 gagacaaaga agtcttaaaa acttatacaa aattgccatt ccctcgtatt acttatgatg
     6721 atgcgatcga attactgaag aaaaatggat ttgatgacat cgaatggggc gaagactttg
     6781 gttcacctca tgaaacgttc attgcgaatt cattcgaaca gcctgtcttt atcctaaact
     6841 atccaaaagc catcaagcca ttctacatga aaccacatcc aacaagagaa gacgtggtga
     6901 tctgtgcaga tatgatcgca ccagaaggtt acggtgaaat tattggcgga agcgaacggg
     6961 caacagacta tgatttcttg ctagaacaaa tccgtaatca cggtttggat gaaaaagaat
     7021 attcatggta tcttgatcta cgtaaatacg gttctgttcc gcactctggt tttggtctag
     7081 gtcttgaacg aacagtcact tggattgctg gtatcgacca tgtacgtgaa gctattccat
     7141 tcccacgttt gttgaaccga atttatccat aagaggtgat gaaaaagctg ttctgcatca
     7201 agtaattaga acagccaagc aaaaacagct gttcatgttt ttgaattggc gggacttatt
     7261 accgcagatg taagcttttg aataccgttt agtggagagg ttgtgaaaaa gctgtttagt
     7321 ttcgagtatt aagaaaaatt ttgtggaaat ggctttccac atttttgcat aaatttggct
     7381 taataccgag aaactggctt ttgaacaccg tttaaggaag aggttgtgcg cctgccgttc
     7441 agctccgagt cacaaggagt aatttcaaaa aacagttttt catgtttgat gactattgtg
     7501 acttgtgacc gaggagttgg ccggagagca ccgtttattc taaaaaagaa ctgcgaactc
     7561 tcgcagttct ttttttaaaa tacgggataa aggaagtttc cagcagacaa gagaagaaag
     7621 caaaagaaat tgctatttga ttcacaaggt tctataacga aatcgcaatc aatcaaacat
     7681 ttacaaagaa ggtaattcaa atggaaatct gatttgatga tgcttctgct gttgaaataa
     7741 agcagcatct agcacctgaa aacaaactaa tagtaacatt cgaagatgga gtaggtccgt
     7801 attttcagca tgcaataatc catatgtaag ttcaattcac ccttgaaatc atcggaccag
     7861 ataaagttat gaccaatcta tcccaagcaa tctagaagag atattagtaa agggacattt
     7921 actagaagtc ttagatgagc ctataaatat atgttctgat ggcgtcatca gtggtctgat
     7981 tgacggaagc ttaggtgtga tcgatctctc tggaccaaac aacgaaggaa tcaaggggaa
     8041 tccggcacgt taagaaaaaa atagcataaa aaactagaca cttgatgagc gttcattcaa
     8101 ttgtttgaag ggactaggct ggtgtcattt tttatacata tattttctct ttcgtcttga
     8161 tagggcttat gggataatat aaggaagaaa atcatcgttt tattcaaaaa ggagtttttg
     8221 acaaatgaaa aaacgtatat tatttatcgg tgatagcatt acagacgcag gaagagaccg
     8281 agcagaagca actgatctag gtaaaggtta tccacttttg attgccggaa aactaatctc
     8341 ccaatatcca acgatggaat ttgaatgcat gaaccgtggg ataggaggag acaaaattgc
     8401 agatctgcaa gtacgctggc aagaagattg tttagcttta caacctgact atgtatcgat
     8461 tttgatcgga atcaatgata cctggcataa tactagcgat caggctatat tcggaactga
     8521 gaaatctgct cagcaatttg aatccgttta tcgaaaatta ctaaatgaac ttcaaacagt
     8581 gggaatctgc aacatcatct tgatggagcc gtttgtactt cctataaccg acgaccgtca
     8641 tggctggcgt aaagacttag accctaaaat ccaaattgtt cgtaaacttg ctaaggaata
     8701 tggcgcattg ctggttcctt tagatggtat attcaatgct ttagggattg tttatggttt
     8761 ttcgaaatat acaagagaag atggggtcca cccaacgatt ggcggacatg agatcattgc
     8821 acaaagctgg atagatgcaa ttgccgcagt cgattttttt agtggagata aaaatgagcg
     8881 aaagaaaagt gagaaatgat ggaaatacgg tgggcagtaa aagaagatct acctcaaatc
     8941 aatcagctga ttactgatca tccagaatca ttcgtaaaag caaaaacggc agctgaccta
     9001 aatgataaga ataaactatt gctcgttgct gtaacaaaag aaaaacggat tatcggattt
     9061 gcgcaagcgg acgtgcaaca gtcagaagaa cgattggatc agcgaccatc aggaaaacta
     9121 atccaacaca cattagtaac aaaagaaaat acggaagaaa tccaaaaaaa atttgcagaa
     9181 tatttgatac tggaagctaa aaaaagaaga ataaaatcat tttttgccca gttttaatca
     9241 aaaacagtaa tagaaggaga aatacaatga gttgtttagg aaatgtcatc tggtttatat
     9301 tcggcggact aatcggtggt cttagctggt tagcagcggg gatactttgg tgtatcacga
     9361 tcataggtat cccaatcggt atgcaatgtt ttaagatcgc ctccctttct tttgcgcctt
     9421 ttggcaaaga agtaatttat caccagtctg gcatgtcatt gattgttaat atcatctggc
     9481 tgatcgtttc aggcctacca attgctctcg cacatgtcgt cagcggcatc cttctatgta
     9541 tcacgatcat agggatacct tttgccaagc aatctttcaa acttgctcga ttggcgttga
     9601 tgccattcgg tgcagaaatt gtataaaaga gaataataaa ggttagataa agcatagagt
     9661 caggtgggat acatgtattt cacctgactc tatgcgttct cctgtataag ttcttccatg
     9721 tgacttttac gtcttttatt tatatggggt tactgtttat ggaaagttga aataattttc
     9781 attaaagaac tctttctata tttttgaaag cgtagtggag cttcgaatat ctgggaagga
     9841 cattttgcag ggattgaaaa aagatattgt cctatcgaaa aattaatgaa tttagacaaa
     9901 ttgccagcaa caggcttcaa acttagttgc tatcctgtca agatcaagaa ggcaagtgcg
     9961 ggttggataa gagcagtggc aatgatcgaa aagaaaaaga aagaataagc caaaacatct
    10021 gtatggaaga aattttccga tgcagatgtt tttcattttt tctttcggat accttgacat
    10081 atgaataacc gttcatttat aattagttat gaagagatat tcatatgttg aggcgaggag
    10141 gtcattaaaa tgaaaagtta cagattagaa ggtttagatt gtgcgaactg tgcaatgaaa
    10201 atcgaaaaag gagttcagaa gatcaatgga gtcaaggaag caacggtaaa cttcacttct
    10261 ggaaaactaa cgattgacgc agaggaagat catttggcta cgattgaaca agaaataaaa
    10321 aaagtagtga aggaattaga accagatgtc aaagtaacag aaatagataa ggaaaaagta
    10381 tctgaacatg gaaatgaaaa agagagaaat acgctgttcc ggattttatt ttcccttgca
    10441 ggtatcgctt tattgctatt atttgatttt aatgaaccaa ttcgcttgat agggtattta
    10501 ttgatttatc tgctgatagg atatgatgta gtgaagaagg cagtgatgaa tatcgtcaaa
    10561 ggaaaaatct ttgatgagaa ttttcttatg tctgttgcta cgattggcgc tatgttgatc
    10621 ggtgaatatc cagaagccgt agcagtgatg ctattttatc aaatcggcga gtatttccaa
    10681 ggattggcag tcagtcattc aagaaaatcg attcgcgaat tgatggcgat ccgtccagaa
    10741 acagctcacg tgcagacgac ggaaggattg atgaccgtga accctgaaga cgtgcagatc
    10801 ggtcagtttg tacttgtgaa gcctggtgaa cgtgtaccgt tagatggaac gatcatcgaa
    10861 ggagaatcat tagtcgatac gtcagcactt acaggagaat cagtccctaa atctgtatat
    10921 gttggtgaaa cagtattaag tggatttatc aataaaaata aaccattttt agttcaagta
    10981 gaaaaatctt atgaaaattc tactatcagc aaattattag aattagtaga aaatgccagc
    11041 agtaaaaaag caccagctga aaatttcatt actaaattcg cgcgctatta cacaccagtc
    11101 gttgtaggat tggccgtttt attagctgtt ttacctccac ttgttgtttc tggagcggcg
    11161 ttttctgaat ggatctatcg agcattgaca tttttagtga tctcatgtcc atgtgcatta
    11221 gtgatctccg taccccttag tttctttggc ggtatcggag gagcaagtaa aatcggtgta
    11281 ttagtaaaag gttcaaatta cttggagttg cttgcacaaa ctgagacagt ggtattcgat
    11341 aaaaccggca cattaacgaa aggtgacttt tcgatccaga cgatcgatac aaaaatcgat
    11401 ccaaagatat tcatgcaata tgttgcgagt gcagaacagt tttctacaca tccgattgct
    11461 caatctgttt tagaaggcta cgcaggtccg cttttaccaa cagctaatat ccaagaattt
    11521 gcaggtgaag ggatcttagc tgaagttgat ggcaaacaag tattagcagg taatcacaaa
    11581 ttgatggaaa gatttgaaat ctcttttcct tcaagtcaag aaatcggtac attgctttat
    11641 ctagcgatcg atcaaagtta cagtggttat cttgttattg cagatacctt gaaagaagat
    11701 gccgtagacg cattggttca attaaaaaag gctggtgtga agaacacagt catgttgacg
    11761 ggcgattcga aaaaaattgc tgatcatatc gggaagcaag taggcgtgga caagatatat
    11821 agcgaattgc ttccagaaga taaagtgcag cggttagagg aaatcttaca aagaaacaat
    11881 aaaaagaccg catttgtcgg agatggaatc aacgatgcac cggtgctagc aagagcagat
    11941 gtaggaatcg caatgggtgg attgggaagc gatgctgcaa ttgaagcagc agatgtagtc
    12001 atcatgaatg atcaaccatc gaagattgca gaagcaatcc atttagcaaa gaaaacattg
    12061 aaaatcgtca aacagaacat tgtctttgct attgggataa aaattttggt acttgcctta
    12121 ggtgcttttg gttttgcatc aatgggagat gcagtatttg cagatgttgg ggtgacagta
    12181 ttagctgttt tgaatgccat gcgaagcttg catgtaaaaa ataaacgttg atcaatgaag
    12241 aggacgaatg aacgtcctct tttttttata tccttttctt aatgaaaaat gtaaagaaaa
    12301 tagataggat tataaaataa ctaatgtttt taattttgca gaaaattcaa aatagcttga
    12361 aattcaataa ggtaaatgaa ataaaagaaa ataacttatt tttttgatgg aaaaaatatg
    12421 aaaaaacgat gtgtattaaa taaaagaata cacacataaa ataacactgt cttgtaagtt
    12481 tgttaaaaat tgaatatgat tacatctgga taacaaattt ttatcataaa ggagagaacg
    12541 aatgaacaac aaacaattac gctggtttac tgttgcgtta attgcattta acatggtttg
    12601 gggcatgggg aatgtagtta ataactatgc tcagcaagga gtatcagttg tcacctcttg
    12661 gctattgatt ttggccattt attttattcc atacgcattg atcgttggac aattagggtc
    12721 agccttcaag gatagtaaag gaggcgtcag ttcatgggtc gaaaatacga catctaataa
    12781 acgactggca tactatgccg cttggactta ctgggtcgtc catattcctt atttggcaca
    12841 aaagcctcaa gcaatcctga ttgctggcgg ttgggcagtc caaggaaatg gaaatatcgt
    12901 aaatacgatg tcagtacaaa tggtagcagt tatttcactt attatatttc ttgccttttt
    12961 atatttatca acaaaaggac tttctacttt gaaagtgatt ggcggactgg ccggaacagc
    13021 gatgttcgtc atgtcgatct tatttattct tttagctgta acggcaccgt tcatcaatcc
    13081 aacgatggaa tttgccacac cacatatgaa tcaagtgaaa acatatattc caacatttga
    13141 tttcagttat ttcacaaccg tttcgatgct agtatttgca gttggaggag cggaaaaaat
    13201 atccccttat gtcaactcta caagaaatcc tgcaaaggaa tttcctaaag ggatgatctt
    13261 cttagcagca atggtaggga tttgtgctgt attaggctca gtcgcaatgg gtatgctgtt
    13321 tgctagcgat aatattccta aagacttgat ggcaaatggg gcatacagtg cttttcaaat
    13381 tttaggtaat tactatggta tcggtaactc attgatgatc atttacgcat tgacaaacat
    13441 gattggacaa atctccgcat tagccttttc aattgatgca ccactaaaaa tcttgttagc
    13501 agatgcggat ccagaatttg taccaaactg gctacgtaaa cgtaatcgta aaggtacatt
    13561 ggtgaatggt tatcttctga caggtatact agtaggaatc attattttgt tgccgatctt
    13621 tggtatcaaa gatatgaatg aattagtaaa atggttgacg aacttgaact cagttgtcat
    13681 gccaatgcgt tacctatggg tgttcttggc atatatgatg ttgaataaag cttataagaa
    13741 attcaattct gaatataaat ttgttaaaaa tccaaaaatc ggttttatct ttggtgcttg
    13801 gtgctttgcc ttcactgcgt ttgcatgtat cctaggaatg gtgccaaaag tagattatac
    13861 tgctgatcct aaagcatggt ggttccaatt attcacgaat atcatcacac caattgtctt
    13921 gatcttatta ggtatgatct tgccagcaat tgctcgtcga gacaaaaaca aagaaatcac
    13981 tgaaccagaa acagtggttc agccttaaaa tagaaatact tgttacaaga ggttgtgaca
    14041 gaagtggtca gcttcaagaa ataagaagga atttacgaaa attgcttctc aaatttttgt
    14101 gaagtttcgg cttgtttttc gcagaagcta cttctggaac accgtgaatc agaggttgtg
    14161 aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagccc ctcatatttt
    14221 tcgttttgct gggcttatta ccgcagatgc aagcttttga acaccgttta agaaagaggt
    14281 agtgagcctg ccgtttaact ccgagtcaca aggagcaatt tcaaaaaaca acttctcatg
    14341 tttgttgact attgtgcctt gtgaccgagg tgttggcagg agaacaccgt ttaaggaaga
    14401 ggttgtaaaa tcagcgattt gacctgagta ttagaggaac aaacgaaaaa atagctcctc
    14461 atattttgcc gttttttgag ttaatgctga aggtcagctg attgaacacc atttattcga
    14521 aacaagggac tttgacacga cttttgtcac agtcccttgt ttttttgcgg cgttataagt
    14581 ggtatgatcg aaccaaattc caaagagaag tgagggagaa gaatgaagat catcgtgatt
    14641 ggacaaagtg ggtcgggaaa atcgaccctc gcaaggaaga tcaaagaaat caccgacttt
    14701 ccgctactgc cgctagacct tttatggcat acaacagact acagtattca ggcaaaaaag
    14761 tggtttttgc aagaacagca atcgtttatg gtatctaatc cgtcatggat tgttgaagga
    14821 aattatactt ctacattaga ggaaaggatt aaagaagcag ataagatcat ttggcttaaa
    14881 gtgccgcgtt atctcgccat ctaccgagta gtttggcgtt ctctaaaaag aaagataaac
    14941 aaaaaatctc ggccagatat gcctgaatca ttttcagaga aactaaacag ggaatactta
    15001 gaatttttat cttttatctg gcattttgaa gaaaacaatg aaccgaaaat acagcagctg
    15061 atccaagtag ctaatgcaag aaataaactg atcatcctta aaacaagacg agagaaacaa
    15121 gaatttttaa ctaaattgaa aatagagagc aaaaataatt gacagttttt gtttacaagc
    15181 gtaatctgta ttcataagct aatgattaca tttgtaaacg aaaggtgtga aataaatgga
    15241 aaaagtcaaa acgccagtaa agatcagtga ttcagagtgg gagatcatgc gtgttatttg
    15301 gacacttgga cagacgacag cccaagaaat cacgcagatc ttagctgatt cgatggattg
    15361 gaaaccagca acgatcaaaa ctttgctggg acgtttggta aaaaaagaag tgatctggac
    15421 agaacaagaa ggaaaaaaat tcatttatca tccagctgtc tcggagatgg aaacagttcg
    15481 cagtgcgacg gaaaatcttt tttcccatat ctgtgcaaaa aggattggag agacgattgc
    15541 ggatctagta gaagaagcca ctttgactca agaagatatc aatgagattt tgaaacaact
    15601 ggaacaaaag caaccagtag atacgatcga atgtaactgt atcccaggtc aatgtgaatg
    15661 taaacaacat caataggagg aagaaaaaat gaaacaacaa ttttcaatcg aaggtatgag
    15721 ctgcaatcat tgtgcagcaa gagtagaaga aacagtaagc gcacttgacg gcgtgcaaaa
    15781 agtgaaagta aatttgaaaa aagcaaacgg tacggtcaag tttgatgaaa caaaagttca
    15841 atccgaaaag atttgtcaag caatcaatgg attgggttat aaagcagagg tgatttgatg
    15901 gcaacagcag aaaccaaaat ggatacgttc gtcattacag gtatgacttg tgcaaattgt
    15961 tctgctagga tcgaaaaaga gctgaacgga caacctggtg tggtcaatgc cacagtcaac
    16021 ttggccactg aaaaagcaag tgtcaaatat gaagggacga ccactgaaaa attaatccaa
    16081 agcgtagaaa acatcggtta tggtgcaatt ttgtacgatg aagcccacaa acaaaaaatt
    16141 gcagaagaaa agcaagcgta tttgaaaaaa atgctattcg atcttatatt gagtacggtt
    16201 ttgactttgc cgttgatgtt gtcaatgatt gctatgatgt taggaagcca tgcggcgatt
    16261 gttcactttt ttcattttcc aatcgtccag ttagtgctgt ctgctcctgt ccaattttat
    16321 gtcggtgctc gtttttataa aggtgcgtac catgcaatca agacgaaagc accaaatatg
    16381 gatgtattgg tagcaattgg aacatcggct gcctttgcat tgagcattta caacggattt
    16441 ttccgtggac acccccaaga tctttatttt gaaagcagca gtatgatcat cacgctgatt
    16501 ttgctcggca aatatttgga acatacagca aaaacgaaaa caggtaatgc aatcaaacaa
    16561 ttgatgtctc ttcaaacaaa aaccgcccaa gtgataagaa acgggaaaga agaaacgtta
    16621 gcgattgaag aagtagtcgt tggtgatcaa ctagtcatcc gtcctggtga gcagattcca
    16681 gcagatggtc gaattatttc aggaagcagt gcgatagatg aaagtatgct tactggtgaa
    16741 aatcttcctg tagaaaagaa tccggatgac acgctttttg gcgggacaat caatacgaat
    16801 ggtctgctac acatggaagt cacacaagtc ggcaagcaga cagtattagc gcaaatcatt
    16861 caaatggtgg aagatgctca agggagcaaa gccccaatcc aaaaaatcgc agatcggatc
    16921 tcagggattt ttgttccgat cgtattagtc atcgcgttta tcacgctcat agctacaggt
    16981 ttgatcactg gtgattggca actcgcattg atccatagtg tctctgtatt agtcattgcg
    17041 tgtccatgtg cattaggttt agcgacccca acagctatta tggtaggaac gggtgttggt
    17101 gcacgaaatg gaattttaat taaaggcgga gaagcattag aagcagctgc tcacttagac
    17161 agcattgttt tggataaaac tggaacgatt acagaaggaa agcccaaagt tacagatcta
    17221 gtcggttcaa aagaagtcct atctattttt tatactttag aacaagcttc tgaacatcca
    17281 ctaggtaaag caatcgtgga atacggaaaa ctgcaagaag cagcaacata cgatatgatt
    17341 gattttacag cccacccagg tgctgggatc agcggtacga ttaatggagt acgctatttt
    17401 gcgggtacac gtaaacgatt aattgaattg aacctatcat ttgatgaata ccaagaacac
    17461 gcgttagaat tagaacagca gggaaaaaca gtcatgtttt tagctgatga aaagcaagtg
    17521 atcgggtgga ttgccgtggc tgatcaaatc aaactagaag ccaaacaagc aatcaagcag
    17581 ctccagaata aaggattaga tgtttttatg ctgacaggag acaacaaact ggcagccgaa
    17641 acgattggta aacaagttgg tattgatcca aagcatatct ttgctgaagt acttccagag
    17701 gataaagcag cctacgtaga aaaacttcag aaagatggca aaaaagtcgg tatggcaggc
    17761 gatggaatca atgatgcacc ggccttagca ttagctgatg tcggtatggc aatgggaagt
    17821 ggaacggaca ttgcgatgga aacagccgat gtgacgctga tgaatagcag tttggcatcc
    17881 attgcacaaa caatcgagtt gtctaggttg acattgagaa aaatcaaaca aaatcttttc
    17941 tgggcttttg tctataatac gattggtatt ccttttgccg cactaggctt tttgaatcca
    18001 atcattgcag gaggagcgat ggcgtttagt tccgtcagtg tattgttgaa ctccctgagc
    18061 ttaaatcgac acatgaaaaa gtaagagaag ggatggagta aaaatgaatg ggaacgatat
    18121 ggagaaaaaa catgagcata aaaaagaagt agtaaacaaa gaaagtacag aatctcatga
    18181 aaaacagatg gagatgaaac atgaccatag tcagatggat cattccatgc acatgggaca
    18241 taaccatgga gatatagcaa acagcaaaca aatggaccat tcgatgcaca tggatcacga
    18301 acacggcggc atggatcatt ccatgcacat ggggaatttc aaacaaaaat tttggctatc
    18361 gcttatccta gctatcccaa tcattctttt ttcaccaatg atgggaatgg aatttccatt
    18421 tcaagtaacg tttcctggtt ctgattggct cgtattgatc ttagcaacta tactatttat
    18481 ctatggcggt cagccatttt taagtggagc taagatggaa ttgaaacaaa aaagtcctgc
    18541 tatgatgaca ctgatcgcga tggggattac agttgcatat atttatagtg tctattcgtt
    18601 tatcgcaaat ctgctcaatc cacatacaca cgtcatggat ttcttctggg aattggctac
    18661 tttgatcgtt attatgctac taggtcactg gattgaaatg aatgctgtgt cgaatgccag
    18721 caatgcttta caaaaactag cagaattact gccagaatca gtgaaacgct tgacgaaaga
    18781 tggaaaagaa gagacagttt cattgaaaga agtaaacgaa ggtgatcgtt tgatcgtccg
    18841 gtctggtgat aaaatgccaa cagatggtgt aatcttgaaa ggtgaaacaa ttgttgacga
    18901 atcagctgtg actggcgaat caagaggaat caaaaaacaa gccaatgaca aagtgattgg
    18961 cggttctatc aatggggatg gaacgatcga aatcgaagta actggaactg gtgaaaatgg
    19021 ttatctagcg aaggttatgg aaatggtgcg aaaagcacaa ggagaaaaat ccaagctaga
    19081 gtcattatct gacaaagtgg caaaatggct gttttatgtc gcattaattg tgggtatcct
    19141 ggcattcatc gcctggttgt tcttgacaga tcttcctaat gcattagaac gtatggtaac
    19201 agtctttatc atcgcctgtc ctcatgctct aggtttagct atcccattag ttgttgctcg
    19261 ctccacatca atagcagcta aaaacggatt acttttgaaa aaccgcaatg cactggagca
    19321 agccaatgat ctagatgtga tcatgctgga caaaacagga acactaacag aaggaaaatt
    19381 tactgtaacg ggtgtcgaag tacttgatga tgcgttcaat aaaaatgaaa tccttcaata
    19441 tctaggagcc ttggaagcga atgccaatca tccattggct gttggcatta tgaattattt
    19501 gaaagaacat gaaatcaagc cttatcaagc tgaaaatcta aaaaatcttt caggagtcgg
    19561 gctagaggca acagtcaaaa aacaacaagt gaaaatagtt aatgaaaaag aagttgagcg
    19621 tctcggatta aacgtagaac aagcattatt gaaaccttac caagaacaag gaaataccat
    19681 cagcttcctg attttagaaa atcatctagc tgcaatcgtt gctttaggtg acgtagtaaa
    19741 aacagaagca aaagaattta tccgaacatt gaaagaaaga aaaatcactc ctgtcatgct
    19801 tactggtgac aataaaaacg ctgcccaagc agtagcagat tatttaggga tcgaagaata
    19861 ttatggcggt ttattaccag atgataaaga agctgttgtc cagaaatacc ttgaccaagg
    19921 gaaaaaagta atcatggtgg gtgatgggat caatgatgcg ccaagtttag cccgtgcttc
    19981 aatcgggatg gcaatcggtg cagggacaga tatcgcaatc gattctgcgg atgtcgtatt
    20041 gacaaacagc gatccaaaag atattttgca ttttcttgat ctagccaagc aaacgcgaaa
    20101 gaaaatgatc cagaacctct ggtggggggc aggttacaat attcttgcaa ttccgctagc
    20161 agccggaatt cttgcgccaa ttggtatcat attaagtcca gcagttggtg ctgtcttgat
    20221 gtcgttaagt acggtagttg tagctctaaa tgctttgaca ttgaaaatca aataataatg
    20281 aaaaaa
//
LOCUS       DACCVZ010000050        20252 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.050, whole genome shotgun sequence.
ACCESSION   DACCVZ010000050 DACCVZ010000000
VERSION     DACCVZ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.050"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            225..1082
                     /locus_tag="IVW63_001806"
     CDS             225..1082
                     /locus_tag="IVW63_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAP7860080.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1197..2117
                     /gene="pstC"
                     /locus_tag="IVW63_001807"
     CDS             1197..2117
                     /gene="pstC"
                     /locus_tag="IVW63_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAP7860081.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2117..3001
                     /gene="pstA"
                     /locus_tag="IVW63_001808"
     CDS             2117..3001
                     /gene="pstA"
                     /locus_tag="IVW63_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAP7860082.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            3016..3822
                     /gene="pstB"
                     /locus_tag="IVW63_001809"
     CDS             3016..3822
                     /gene="pstB"
                     /locus_tag="IVW63_001809"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAP7860083.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3838..4596
                     /locus_tag="IVW63_001810"
     CDS             3838..4596
                     /locus_tag="IVW63_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAP7860084.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4609..5286
                     /gene="phoU"
                     /locus_tag="IVW63_001811"
     CDS             4609..5286
                     /gene="phoU"
                     /locus_tag="IVW63_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAP7860085.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5524..6554
                     /locus_tag="IVW63_001812"
                     /pseudo
     CDS             5524..6554
                     /locus_tag="IVW63_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
     gene            6551..7318
                     /locus_tag="IVW63_001813"
     CDS             6551..7318
                     /locus_tag="IVW63_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAP7860086.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7418..8986
                     /gene="liaX"
                     /locus_tag="IVW63_001814"
     CDS             7418..8986
                     /gene="liaX"
                     /locus_tag="IVW63_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HAP7860087.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9286..9603
                     /locus_tag="IVW63_001815"
     CDS             9286..9603
                     /locus_tag="IVW63_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HAP7860088.1"
                     /translation="MKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVAF
                     GSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDEW
                     SDF"
     gene            9603..9953
                     /locus_tag="IVW63_001816"
     CDS             9603..9953
                     /locus_tag="IVW63_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAP7860089.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10120..11058
                     /locus_tag="IVW63_001817"
     CDS             10120..11058
                     /locus_tag="IVW63_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAP7860090.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            11073..11903
                     /locus_tag="IVW63_001818"
     CDS             11073..11903
                     /locus_tag="IVW63_001818"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAP7860091.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKLHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11947..12972
                     /locus_tag="IVW63_001819"
     CDS             11947..12972
                     /locus_tag="IVW63_001819"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAP7860092.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12987..13925
                     /gene="galU"
                     /locus_tag="IVW63_001820"
     CDS             12987..13925
                     /gene="galU"
                     /locus_tag="IVW63_001820"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAP7860093.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            14050..14490
                     /locus_tag="IVW63_001821"
     CDS             14050..14490
                     /locus_tag="IVW63_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAP7860094.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKATAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14493..15095
                     /locus_tag="IVW63_001822"
     CDS             14493..15095
                     /locus_tag="IVW63_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAP7860095.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15154..16260)
                     /locus_tag="IVW63_001823"
     CDS             complement(15154..16260)
                     /locus_tag="IVW63_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAP7860096.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16470..17471
                     /gene="ccpA"
                     /locus_tag="IVW63_001824"
     CDS             16470..17471
                     /gene="ccpA"
                     /locus_tag="IVW63_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HAP7860097.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17807..20152)
                     /locus_tag="IVW63_001825"
     CDS             complement(17807..20152)
                     /locus_tag="IVW63_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAP7860098.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
BASE COUNT         6442 a         3574 c         4307 g         5929 t
ORIGIN      
        1 ttaactttgg ggtatctctt gttttttggg gaaagcaaga aataagctaa tatatgctat
       61 taaaagagac acatttcaaa gccagtatag catagaaact tttaatgaga tagttttttt
      121 tacaattatg agaatttatt ttgttattta atgattttga ttcgttttca tcaagtaatg
      181 aaaatgataa aataaacata ctttaggatt aaaggagatt tctaatgaaa aaacttaaat
      241 tattcttacc aataatagga ttagccattc ttttatcagg ctgttcaaag tggattgatc
      301 gaggagaatc cattacggct gttggctctt ctgctttaca gcctttagta gaaacagttg
      361 ctgaaactta ccagacagaa aatcctggaa aattcatcaa tgtacaaggg ggcggaagcg
      421 gaactggttt gtctcaagta cagtcaggag cagtcgacat cggaaactct gatttgtttg
      481 cggaagaaaa atcggggatc gatgcctcag cattagtcga tcatcgagta gcagttgttg
      541 ggatcactcc tattgtgaac aaggatattg gcgtaaaaga catcagtatg gaaaacctga
      601 aaaaactatt tacaggcgag atcaaaaact ggagtgaagt cggtggaaaa gatcagccag
      661 tagttatatt gaaccgcgct tcaggaagcg gaacccgtag cacgtttgaa aaatgggtat
      721 tggacggaga aacagctgtt caggcacaag aacaagattc aagcggaatg gtgcgccaga
      781 tcgttgccga cacacccggt gcaatcagct atgttgcttt ttcttatgtt tccgatgatg
      841 tagatacgtt gaatgttaac ggtgtagaac cgacagatga aaatgtgaca acgaacaaat
      901 ggacgatttg ggcatatgag catatgtaca caagagatca tccaaaaaaa ctgacaaaag
      961 aatttttaga ctatatctta tctgatgaag tacaagataa catcgttgga gaactaggtt
     1021 atatccctgt ttctcatatg aaagtcgaac gtgattggca aggaaatatc gttaaagagt
     1081 aatctttaca caaaatttac aaacttagct aaacttttac atgttattaa aaccaaattg
     1141 atgttcaatt tgtacactga gtgagtatgt taaacctgat taagggggag tcatctgtgg
     1201 aagatgtgaa aaaagtatta ttaacaaaat caaaacgttc aaaaatggaa cagcgtggaa
     1261 aattcatcag ttttttatgt atcgcgctga tcgtgttggt tgtattatct attttttatt
     1321 ttgtagctag taaaggattg gccacctttt ttactgataa gatcaatgta tttgattttc
     1381 tgtttggtac agattggaat ccaagccaaa tcggagcaaa tgggaaacca atggtagggg
     1441 cattgcctat gatcacaggt tcgtttattg tgaccttttt atctgctatc gttgccacgc
     1501 catttgccat tggtgcagca gtattcatga cggagatctc tcctaaaaac ggaacgaaga
     1561 tcttacagcc ggtcatcgag ctgcttgtag gtattccttc tgtcgtttat ggttttatcg
     1621 gtttatcagt tatcgtgcct tttgtcagaa gtatttttgg cgggacaggg tttggtatct
     1681 tagctggtac atttgtgttg ttcgttatga tcttgccgac tgtcacaacg atgactgttg
     1741 atgcattaaa ggcagtgcca cggcactatc gggaagcttc attagcgctt ggtgccacaa
     1801 gatggcaaac aatctacaaa gtcgtgctac gagcagccgt gcccgggatt ttaacagcag
     1861 tcgtttttgg tatggctcgt gcgtttggtg aagccttagc tatccaaatg gtcatcggta
     1921 atgcagcatt gatgccaaca ggacttacta ctcctgcttc tacattgacg tccatcttaa
     1981 caatgggaat cggaaataca atcatgggaa cagttgaaaa taatgtgtta tggtcattag
     2041 cgctgatctt gctattgatg tcattattct ttaatatcgt gatccgtatg attgggaaga
     2101 aaggagagct gaaataatga acgcaaaacg ctcagataaa attgctacag gtgttttata
     2161 tatagtttcg gggatcatcg tattgatttt agcagcttta ctactttata tcttagttcg
     2221 gggaataccg catatttcat ggtccttctt gaccgaacct tccaaagcct accaagaagg
     2281 cggtggaatc gggatccagc tatttaactc gatttatttg cttttgatca cgatgatcat
     2341 cagttttcct atttctttag gtgcgggtat ctatctttca gaatatgctg gaaaaaactg
     2401 gctaacagat gtgattcgca cgtcgattga aatcttgagc tcgttgcctt ctgtcgttgt
     2461 cggtttattc ggtttcttgg ttttcgttat tcaattccag tatggtttct cgattatttc
     2521 tggtgcattg gctttgactg tattcaactt gcctcttttg actagaacag ttgaggagtc
     2581 tttacaagcg gtccattaca cacaacgaga agcaggattg gccttaggtt tgtcacgctg
     2641 ggaaacagtg ataaaagtgg tggttccaga agcgacacca gggattttga ctggtgtgat
     2701 cctaagttct ggaagaattt ttggtgaagc agctgcattg atctatacgg ctggacaaag
     2761 tgcacctgcg ttagatttta cgaactggaa tccattaagt gtttcaagcc cgatcagcat
     2821 tttccgtcaa gctgaaacat tagctgtcca tatttggaag atcaatacag aaggcacgat
     2881 gcctgatggt gtttctgttt cggctggcgc ttctgccgtg ttgatcattg ctgttttact
     2941 gttcaacttc ggcgctcgtg cgattggcaa acgattatac cgaaaaatga cttcagccta
     3001 aggagaagaa gcaaaatgaa aaaatataac tggaatgaaa caaatgtcat caccatgcca
     3061 aaagagaaag aagtagcact atatacggat gatctacatg tctggtatgg cgacaatgaa
     3121 gcaatcaaag gagtggatct ggaatttgaa aaaaataaga tcactgcact gattggtcct
     3181 tccggctgcg gaaaatctac gtatcttcgt tcgttgaatc gaatgaatga tgggatcgct
     3241 aatacgaaaa tcactgggaa aatcatgtat caaggcgtag atattaatgc gcctcaagtg
     3301 gatgtttatg agatgcgcaa acggattggc atggtttttc aacgtcctaa tccgttcagc
     3361 aagtcgattt atgacaatat tacatttgct ttgaaacagc acggcgaaaa aaacaaaaag
     3421 aaattagatg aaatcgttga aacaagcttg aaacaagctg ccttgtggga ccaagtaaaa
     3481 gacagcttgg acaaaagtgc cttggcttta tctggcgggc aacagcaacg tttatgtatt
     3541 gctcgtgcga tcgcgatgaa acctgatatc ttgctgctag acgagccggc aagtgctttg
     3601 gaccctattt cgacaggaac ggttgaagaa acacttgtaa acttgaaaga agactatacg
     3661 atcatcatcg tgacgcataa catgcaacaa gcagctcgta tcagcgacta tactgccttt
     3721 ttctatctag gaaaagtaat ggaatatgac aaaactaaca agatatttac cagaccaaaa
     3781 attcaggcaa ccgaagatta tgtgtccggt cattttggtt aagacggagg cctcaacatg
     3841 acaaaagaaa ttatttcatc taaagatctt catctgtatt atggaaagaa agaagcacta
     3901 aaagggatca atctaagttt caatcaaggg gaaatcactg cgatgatcgg tccttctggt
     3961 tgcgggaaat ccacttatct gcgttctttg aaccggatga atgacctgat tccgaatgta
     4021 acgatcaccg gaagtgtttt atataaagac aaagacatct atggtccaaa aacagatgtt
     4081 gttgaactaa gaaaagaaat cggcatggta ttccagcagc caaacccatt tcctttttct
     4141 atctatgaaa atgtcatcta tggattgaaa ttaaaagggg aaaaagataa aaaagtcctt
     4201 gatcaagtag ttgaagaaag cctgaaggca gcgtctgttt gggatgatgt gaaagacaaa
     4261 ttgcataaaa gtgctttatc tttatccggt gggcagcagc agcgtgtatg tatcgcacgt
     4321 gttttggcag ttaatccgga aatcatctta ttggatgaac caacaagtgc gcttgatcct
     4381 gtttctactg ggaaaatcga aagtatgctg ttagaattaa gagagcggta tacgatgatc
     4441 atcgtgaccc ataatatgtc tcaagcttca cgtatttcag ataagacggc attcttttta
     4501 gatggtcact tgatcgaata caacgatacg aagaagatat tcatgaatcc agaaaaacaa
     4561 gagacagaag attatatttc aggtcgattt ggataaggag gaaacggaat gctacgtaca
     4621 caatttgaag aagaattgct gaatctccat aatcagttct acgaaatggg gatgatggtg
     4681 agcagcgccg tgcacaagtc agttcgtgca tacatcaaac acgataaaat cttagcccaa
     4741 gaagttatcg aaaacgatat aaatatcaat aacatggaaa cacgcttgga aaagaaaagt
     4801 tttgaaatga tcgcattgca acagccagtt acaactgatt tgcgtatgat cattacggtc
     4861 atgaaagcta gctcggattt agaacgtatg gccgatcatg cggtgtctgt tgctaaatcc
     4921 acgattcgcg taaaagggca gacgagaata ccggaaatcg aaaaagagat ctccgatatg
     4981 tccgattatg tgaaaaaaat ggtggacaac gtcctagtag cttatgtcaa aacagacgaa
     5041 aaagacgcac gtacgatcgc caatatggat caaagagtca atgactattt caatcgaatc
     5101 tataatgcaa caatcaaaaa tatgcaggaa aatcctgaga cagtcatcag tggaacagac
     5161 tacttgaatg ttgccagtta tctagaacgg atcggagact atgtgacaaa catctgtgaa
     5221 tggatcgtct acttggctac agggaaaatc actgagttaa atacgaacca caatgagatt
     5281 ttctaaactg aagctgtgat tatgccgttt gtttaggaaa agaggttgtg aaatcagcgg
     5341 ttgtgaaaaa gctgttctgc atcaagtaat aagaacagtc aaacaaaaaa tagctcctca
     5401 tatttttcgt ttggctggac ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     5461 ggaaagggtt tgtgacaaaa catgtcacaa acccttttca tcatttcata gaaaggataa
     5521 agaatgcaaa aaaaaattag catcatcact atatttttta tttgtgtgct tacttcatgg
     5581 gttattcagc atcaagctgc tttatatgaa gtacctgtca tcgagatcga aaaagtacga
     5641 ataaaagagg atcatcaatt gattacagga agactgatga acacggatca aaaaggagaa
     5701 tcgatttatt tatcggttcc ttatcaaaaa aatcaaatag aaacagcaaa tataaaagcg
     5761 agacaaatgt atctagtcca aatgcatgga gatgaatggc agctagtagc aaaaaaaaat
     5821 gatggctggc ttttcttctt cacaagtatc ttcattggcg ccatgttgct tattggcgga
     5881 aaacagggtc tatttgcttt aggaagtctc atcatcaata tcgttttact ttacttttgt
     5941 tgctcatctt tactaaaaca gaagggattt ctctattaaa tatatctatc ctgttcgtcg
     6001 ttatagggat gattattagc atattggctt taaatggatg gaatagaagc agtataatca
     6061 aaatttcagc tgcagttacg agtgtttttt tagcattttt tatttgtctt ttgacaatga
     6121 atcattggaa agaccaagga ctgcgctatg aggaactgaa ttatctgaca cgaccgtatc
     6181 gttctgtttt tctttctagc gtactgattg gaacagctgg aggaacactc gataccgtta
     6241 tcacagtcat tgcgacatta gaagaattga ctaagcgaca accagaaata acagcgaaac
     6301 agttatggct ttcaggaagg caagtgggtc gagatgtgat tggctcgatg accaatatcc
     6361 ttttgttcgt ctatatcagt gggtcagttc catcgcttct tttatattta ggaaatcaat
     6421 ggtcgttcaa agaaacgata gaacagcatt tatcattgga atttttacgc gtcattgctg
     6481 gcagcttagg aatagtatta tcgatcccta tctcggtcct cttttttctg actgtaagga
     6541 ggctgaaacg atgaatgtac ttattatact tgttgggatt ttagcaatca gcgtgctact
     6601 tattggcggt acgcaaggta tgtatattct tttaggctta ttcatcaatt tagggatctt
     6661 tttcctgttg ttattcggtt atcatcagaa gtggccgata ctggcattgt cggtcatagg
     6721 atttttattg attgctgtgg ttatcttatt ttttatcaac ggttataatc taaaaatgcg
     6781 tgcagctttt gtgagtatac tgatcttttt attttgtttc ctactattgc ttcctatcac
     6841 tgatttttta gcgatccaag gttttacatc ggtagaacta gaagaattat ctggcttaga
     6901 taagacttta gcgattgatt ttagattact tacgagatcg ttgcttctga ttagtcttag
     6961 tggtgctgtt ttagatgcta gtgtagcaat ttctagtggg acattcgaag tatatcaggc
     7021 aaatccgcaa ttatcttttt accaattgcg ccattctagt ttcgctattg ctaaaaaaat
     7081 attggcgtca acagtaatga cacttctttt tgcattcatg ggaagttctt tagcgttgat
     7141 cctctggttt attgatttag acattccttt tcagcaagtg atcaatgaaa aatcatttgt
     7201 tctagaatat acgatggcta ttcttaccac attgtctgca ctacttgttc ttcctttaac
     7261 ctgcgtgact acagcatatc tctttacaaa aaagaaagaa caactcaaga tggagtaaaa
     7321 gttacaactt aagtcctatg acatttttac tgaatcagtg cataatatgg atgtaaggaa
     7381 aagcttgcaa acaattttgc ttaaggaggc aatttccatg aaagaaagag aacgtatttt
     7441 agatttagtg aaaaaaggaa tcctttcgac tgaagaaggc ttagatttat tagaaagcat
     7501 ggcaactgaa aaagacgaaa agcaaataaa aaaagaagca gacaaggtaa ctgctagtca
     7561 taaagaaaaa gatcaggcaa gtcaattgat cgataaactt gaaaacggcg aagaagaaat
     7621 ttctgagcca gttgatccaa aggaaagaga aagacaagat caagaaaact tagaaaagat
     7681 cttagatgaa ctagcaactg aagcgaataa aacttcggcg cgtctagatg aagtaaatgc
     7741 tcaattcgct gacaataagg cagcacgcaa tgagaaacag gaagcattga tgcagctgaa
     7801 tacaaaagaa gaattaggcg agttgacaga agaagaatta gcacagcgtc agacgttaga
     7861 agcagaaatc aaagaattag aagctagtgg cgatacactg ttagaagaac aattgaaatt
     7921 agaagcagaa ttaaaagata tccgtaagaa tcaatggtct gagaaaaaag aaacgtttac
     7981 tgataagttt gaattgccag atgattggaa agatcaagca acagatacac tgaatcaagt
     8041 aggcgaaaaa atgtcagaag ctggatcaca gttaggcaaa ttcttgaaga aaacattcca
     8101 aactgtttca gaaacagtga atgacaacat ggaatggaaa gatgtcagct tacgtgtccc
     8161 tgggattgcg acaacgaaat ttgagcatga attttactat gaagctcctg cagcaagtat
     8221 ccttgatatc aaggcagcaa acggaaacgt gacgttaaaa acgtgggaca gcaacgatgt
     8281 gaaagttgaa gctaagatca aactttacgg aaaaatgggt gctgaaccat ttgaagcatt
     8341 ctctgaacgg agccagattg aggttaatga agatcatatc tccttccaaa ttccaaataa
     8401 acgtgtgcgt gcagaccttg ttttctactt acctaaacga gtatacgacc acgcagctat
     8461 taaacttcta aatggcaaca tcatgattga aacattggaa gctaaagata tttatacaaa
     8521 atctacgaat ggtaacatca tcgtggacca attaactgca acgatgctgg aagtagaagg
     8581 tgtaaacggc aatatcgata ttcgaaacgg gaacatctta gattctatta tcgaaacagt
     8641 aaatggtaca gtgacatttg gtgcgacagc agaaaacctt tctgtgtctt tggtaaatgg
     8701 tgatgtacgt cttacgatta aagaagataa tttgaaaaaa gtagaagcaa gttcagtgaa
     8761 cggaaatgtc aaagtcgctt taccagatgg catcggtttg gaaggacatg ctaaaacaag
     8821 tcttggaagt atcaacagcc gtctgtccaa ttacgaagta gttcgtgaga aaaaagaacg
     8881 gacaaaccaa atgttgcaat tccgtcgtgt ttcagatggt gaaatcacgc aagtgcaact
     8941 ttcaacgaca acaggaagta tctatttaaa agatacagat aaataaagag gttgtgaaag
     9001 agatgttcag ccttgagcaa taagaagcga ttttgtaaaa tagcttcccc tattttacaa
     9061 aattgtgcct tattgccgat aggctatctc ttgaacaccg tttaccaaga gattatgaac
     9121 ctgccaatta tcgccgagtc acaaggaata atttcagaaa aagctcgtca cgttttatga
     9181 atatggtaat ttgtgaccga gaattttgca gaaagacacc gattaagaag aaggttgtca
     9241 caacgatttt cttcatttaa aatagtagaa cagaggtgag acatgatgaa aaaaaagttg
     9301 acaaaatcca ataaaaatgt tgttttgaca gggactttag caggaatagg agaatacatc
     9361 gggattgatc cgactgttat ccgtgtgctt tatgtattcc tgagcttagt tgcttttgga
     9421 agtccaatca ttttatacat tttattagct ttgattatcc catctgcgcg ttctgcacga
     9481 acaaactatg gacataacaa tgcatattat gaaaaaaaca attatcgtga acaaactcgt
     9541 gaacaaacaa aaaaacgcaa agaagcggaa aaaatcgatg atgacgaatg gagtgacttt
     9601 taatgtcgta ctttcaacgt attttagtta atacgttaac attcatatca ttggctgttc
     9661 tttttcctgc gatggtccat gtgagcagta tttggacggc cgttcttgcc agcttcgtat
     9721 tgtctgtgtt gaatatgttt gtcaaaccga ttttgacgat actgtccctg ccctttacat
     9781 tagtcacatt gggattgttt acgtttgtta tcaatgcagc gattcttaaa atgacctcct
     9841 tttttgtggg agcagaacat tttagttttt cttcattcgg tgcagcgttg ttagtagcta
     9901 tcttgatgtc gcttgtcaat gtaattgtca gcgaacataa cagtagaaaa taaaagaaag
     9961 ctgtgccgaa ctatcggcgc agttttttta tttagaatca ggaatgcgtt ttctattaca
    10021 ttggtaatta aataaaaacg ttttttttaa ttggtagtac ttttggctag acaatgataa
    10081 aatgatagag aacactctaa tagaaatgag gtagcatgaa tgtcagaagt tgtaaaagtt
    10141 agccaattag tgaaaaaatt atctttggaa atcgtgacag gcgacgagaa aagcttagac
    10201 cgtgtcatcg taactgggga catctcacgc ccaggactag agttgactgg ttattttaat
    10261 tattattccc ataatcgttt acagctattt ggcagtaaag aaatcagttt tgcggaacgg
    10321 atgatcccag aagagcgttt gatcatcatg agaagattat gtagtgaaga tatgcccgca
    10381 tttattattt caagaggatt accggctcca gaagaaatga tccaggcagc aaatgaaaat
    10441 gggatagctg tactgcgttc tcccatctca acttctcgtt tattaggaga attatccagt
    10501 tatttagatg gtcgccttgc ccctcgaaca agtgtccacg gtgttttagt ggatgtttac
    10561 ggattaggtg tactgattca aggtgacagt gggataggaa aaagtgaaac agcgttggag
    10621 ttgatcaaac gcggtcatcg attgatcgca gacgatcgag tagatgttta tcagcaagat
    10681 gaattaacgg tgatcggaga accgcctaaa atcctggaac atctaattga aatccgagga
    10741 atcgggatca ttgatgtaat gaatcttttt ggtgcgagtg cggtacgtgg ctctatgcaa
    10801 gtccagttgg ctgtttatct ggaagcatgg gcaaaagata agaaatacga ccgtctgggc
    10861 tctgaagaca cgaccgttga aatcgcggaa gtgggcattc cacaaataaa aatccctgtc
    10921 aaaacaggac gaaacgttgc aatcatcatt gaagtagccg cgatgaattt ccgtgcacgt
    10981 acaatgggct ttgacgcaac gaaaacattt gaagaaagat taagtcgctt gattgaagaa
    11041 aactcaggca acgactagca aggagtgaca atatgttagc acaaatcaat cgagttgctt
    11101 ttgagcttgt agggattcct atctactggt atgcattgat catcgtatca ggtatcatta
    11161 tcgccatgtg gcttagcagc agagaggctg ttcgggtagg attaaaagca gatgatgtga
    11221 cagattttat gttgtgggga ttgcctatct ccattattgg cgctcgctta tattatgttt
    11281 tatttgatct tccccagtat atagctgatc caatccaaat attcaatatc cgttcaggag
    11341 gcttagctat ttatggcgga ctgattgcag gcgcgatcac gctgtatttt tttactaaat
    11401 atcattttat ttctttgtgg acttttttag atatcgctgc accaagtgta ttattagcac
    11461 aggcaatcgg tcgttgggga aatttcatga accacgaagc atatggacca gacacgacgc
    11521 gaagcttctt agaaagtctg catttaccgc aattcatcat tgataatatg tatatcgaag
    11581 ggatctatcg tcaaccaaca tttctttatg aatcactttg gagtttgatt ggatttattt
    11641 tgcttttgtt tttacgaaag aaactacacc ttttgaaaaa aggcgaagtc cttttatgtt
    11701 atctaatgtg gtatagtttc gggcgtttct ttattgaagg attacgtaca gacagtcttt
    11761 actttttagg tgtgatccgt atttctcaat tattatctgc tgtgttattt gtcggtacat
    11821 tgattctatt tatttggcgc agaaaaaaag gaaatttacc ggattatgac cgctcattag
    11881 gaaaaaatca acaaattatc tgatttttag agcgttaaaa atgaaaaaaa tttcaggagt
    11941 ggtaaaatga attatagagt agcggtttta ggaccaggct cttggggtac tgctttggca
    12001 caagtcctcg ccgaaaacgg acatgacgtt cggatttggg gacatcgtgc ttcacaagta
    12061 gaagaaatca acacccaaca cacgaatcaa cgttatttac cagatcatta tctacccgat
    12121 tccatccaag cattcaccaa tatggaagat gcagtaaaag acgcagatgc ggtgctattc
    12181 gtcattccaa cgaaagcaat acgttctgtt gcaaaagaac tagtgcctaa attgaataca
    12241 aagccagtga tcatccatgc aagtaaagga ttagaacagg gaacacataa aaggatctct
    12301 gacatcttgt tagaggaaat cccagcagaa aaaagaaaag ctgttgttgt tctttctgga
    12361 ccaagccatg cagaagaagt agcgaaacat gacatcacta cgatcacagc tgcaagtaca
    12421 gatgcaaaag cagcaaaata tgtacaagag ctgttcatga ataattattt tcggatctat
    12481 accaatcctg atgtgatcgg tgtagagatg ggggcagctt tgaaaaatat tattgctatt
    12541 ggtgctggcg ctattcacgg cttagggttt ggcgataatg caaaggcagc aatcatgacg
    12601 cgcggattag ctgagatcag ccgtttaggt gtagcaatgg gtgccaaccc gctgaccttt
    12661 atcggattaa gcggagtagg cgatctagtc gttacttgca caagtgttca ttctaggaac
    12721 tggcgcgcag gcaacttgtt aggacaaggg cagcccctag aagaggtgct agccaatatg
    12781 ggaatggtcg ttgaaggtgt gaatactacc caagcagcga tggaactagc ccaaataatg
    12841 gaaatcgaaa tgcccatcac tcaaacaatc tatgaagtgc tgtatgaaca aaaagaaatc
    12901 aaaacagccg caaaagaaat catgttacgt gatgggaaaa aagaaaatga attctcatta
    12961 acaatttttt gaaggagcga atgtatatga aagtcaaaaa agcagttatt ccagcagcag
    13021 gattaggaac aagattttta ccagcaacaa aagctatggc aaaggaaatg ttgccaattg
    13081 ttgataaacc aacaatccag ttcatcgttg aagaagcgtt gaaatcagga atcgaagaca
    13141 tcttgatcgt tacaggaaaa gctaaacgac caatcgaaga tcactttgat tcaaatattg
    13201 aattagaaac aaacctaagt gaaaaaggaa agaccgaatt attgaaatta gtagaagaaa
    13261 cgacagatgt caacttgcat ttcatccgtc aatctcatcc aaagggttta ggacatgccg
    13321 ttcttcaagc aagagccttt attggaaatg aaccgtttgt cgttatgcta ggcgatgata
    13381 tcatggaaga tgaagtacca ttgacacagc aattaatcga tgattacgaa cgtactcatg
    13441 cttctacgat cgccgttatg caagttcctc atgatgaaac ttcaaaatac ggaattatca
    13501 atccaggaga agtattggaa gatgggttat acaatgtcaa aaactttgtt gaaaaaccag
    13561 atccaagcaa agcaccaagt gatttagcta ttattggacg ttacttattg actccagaaa
    13621 tttttgatgt attgtccgag caacaaccag gagccggaaa tgaaatccaa ctaactgacg
    13681 caatcgatac attgaataaa acacaacgcg tatttgcccg taaattcaca ggtaaacgtt
    13741 acgatgtcgg tgacaaattt ggttttatga aaacaagtat tgaatatggt ctaacacatc
    13801 cagaagtagg tgcaccttta cgtgagtata tcctgtcttt aggtaaaaca ttagaagcag
    13861 aaggaagcaa gatcgatcat aatccaaaag gaataacaga aatcaaagaa gaaaagaaaa
    13921 aataaccctt ttttctaacg agcttcagct gctaattgaa taaaaagtag ttgaagctcg
    13981 tttttatttg tttaaaaaac acgaaaatgc tatccttata gaaaagagag acaagaaggg
    14041 agtttgatca tgtcaggagg agaaattgca ggattgattg cagcaatcgc ctttgcgata
    14101 cttgtcgttt ttatcgttcg tgtgttgttg caagtttcta aaactttaga aaaagtagat
    14161 cagactgtag cagaagcaaa tacgacgatc gaaatcgtca caaaagacgt agatcttttg
    14221 tctagacaag tagaaggctt gctggtcaaa agtaatgaac tgctcttgga tatcaatgga
    14281 aaagtcgcaa cgatcgatcc attgttcaca gcagttgctg atttaagtga aagtgtatca
    14341 gaacttaatc attctagtaa aaacatcgcg acgaaagtcg gcggaatcgg taaagcgaca
    14401 gctaaagcga cggttgccgg aaaagtcggt gggacagcga tgaaattttt taaaaacaaa
    14461 aaacatactg aaacgacagg aggaaaataa aaatggctaa aaaaggtgga tttttattag
    14521 gtgcagtagt cggaggaaca gccgcagcaa tcgccgcgtt attgttagca ccaaaatctg
    14581 gtaaagaact tcgggatgaa ttagctgccc aagcggatga tttgatggat atggcttcag
    14641 attacacaga tatggcgaaa gaaaaatcga ctgagttaac aggtattgca aaagaaaaag
    14701 cgcaagatct ttctcaacaa gcaggtgatc tagcaggtag tgtcaaacaa aaagtaagtg
    14761 aatcagcaga tgaagcagga agtgaatctg acgatatctt gttaaatctt aaagaacaat
    14821 cagctgactt atctaatcgt ttcaaaaaaa cggcagaaga tatgaaaaaa cctgcagatg
    14881 aattaggaag tattgctaaa gatacttcag aagatatcat gattgatgta aaagacgctg
    14941 ctggtaaagc aggagatact gtcaatgaag gaatgtcaga agcaaaacca gttgcagatg
    15001 acacaaaaga aatgatgaaa atggcaaaag aagatgcgaa agaagctaaa aaagaaataa
    15061 aagatacaat gacagattca tctacaaatc actaaaatca caaatttata gaataaaaag
    15121 gtgggagcgg actagctctc acctttttta ctcttatttt tctaaaacaa gtaattcttt
    15181 tggtgtagtc gtgaatggca cacagccatc gcttgtcaca tatacacagt cttcgatacg
    15241 tacccctact ttttcaggaa tatagattcc tggttcaaga gagaagcaca tcccttcttc
    15301 gattactaag tcatttcctt ctacaaggga agggaattcg tggacggttg ttccgatccc
    15361 gtgacctaaa cggtgattga aatattcgcc gtagccatag ctgttgatca cgtttcgtgc
    15421 gatttgatca agttcacctg ctgtcacacc tggacggacg gcttcttgtg cggcaagctg
    15481 tgcttcaaga gtgatgttgt atattttttc ttggaagtcg gttggttttt gataagcaat
    15541 tgtacgagta gcatcactgc aatagccatt ccaaacaacg ccaagatcga ataacacaag
    15601 ttcattcggt gaaatcttcg tgtttcctgg tgtaccatga gggcttgcag catttgctcc
    15661 tgcaaggact aatgtgtcga aagacatttg tgaaacacct tgttttttca attggtattc
    15721 gatttctgca atgatcgctt gttcagtcac gccttctttc actgctttaa agccaatctc
    15781 aaatgcaaca tcggcccatt taccagcttc gatcagtttg tctttttcct ctagagtttt
    15841 gatcagttgt agacgttgga tgatggaagt tagatcagtg taagaatccg ttcccgtcaa
    15901 gatatcagag atagcatcga agcgctcgac agtcaaggcg ttcttttcaa tccctacatt
    15961 gccaggctga ccatagcgag cacgaagttc ttttccgatg atctcccaag ggttttcgct
    16021 gtctaaatag ccacggacat catacgccca actactgttt tgagcatctt caacttccaa
    16081 agcaggagtg aaaaggaaag gatcttgttc aagagggata aaaagagcta gtacacgctc
    16141 atgaggatca ctttcgtatc cggaaaagta agcgatgtgg ccagggtcgc tgatataagc
    16201 caattcgact tggtgttgtg ccatccattg acgtagttca ttgattttta cgttattcat
    16261 ttggcaacct actttctaaa ttaattttgt attcaataat tgtaccactg atttattaaa
    16321 agaccaacgt tctaaaaact gaaaaaagta aaaattttca tgaaaacaga gataaaacgg
    16381 ttgcaattct tgagattatt tgatattcta ttttagaaat gtaagacgta ttttcagaaa
    16441 acatataaaa tatgaatagg agaacacaaa tggaaaagca aacaatcact atctatgatg
    16501 tagcgagaga ggcaaatgtt tcgatggcta ctgtttcacg tgtcgtaaat ggcaatccaa
    16561 acgtcaaacc agcaacaaga aaaaaagtct tggaagttat cgatcgcttg gattatcgtc
    16621 caaacgcagt tgcgcgtggc ttggcaagta agaaaacaac aacagttggg gtaatcatcc
    16681 ctgatgtcag caatatgttc tttgcttctt tagcacgtgg tatcgatgat gtggcaacaa
    16741 tgtacaaata caatattatc ttagcaaatt cagatggtaa cgaccaaaaa gaagtcaatg
    16801 tattgaataa cttactggct aagcaagtgg acggcgtgat cttcatgggt caccatatca
    16861 cagacgaaat ccgtggagaa ttttcacgtt caaaaactcc tgttgtatta gctggctcta
    16921 ttgatccaga tgaacaagta ggtagcgtaa acattgatta tgtatcagca acaaaagatg
    16981 cagtaaacaa attggcaaaa agcggcaata aaaaaattgc ttttgtcagt ggtgcgttga
    17041 tcgatcctat caatggacaa aatcgtctga aaggctataa agaagcatta agcgaaaata
    17101 acctaccata tagcgaagga ttgatctttg aagcacaata caacttcaaa gatggtctat
    17161 ctctagtcga tcggatccat aatagcggtg caacagctgt ctatgtttca gatgatgaat
    17221 tagccatcgg tattttggat ggtttattag accgtggcgt gaaagtaccg gaagaattcg
    17281 aaatcatcac aagtaacaat tcactactga cagaagtagc tcgtcctcgt ttaacaagta
    17341 tcacacaacc attatacgat ttaggggcgg tatctatgcg cctattgacg aaaatgatga
    17401 ataaagaaga agtcgaagaa aaaacgatta tcttgcctta tggaatcgaa gaaaaaggat
    17461 ctacaaaata ataaaaggac aaccattcag aggttgtgag cctgccgttt aactctgcgt
    17521 tacaaggagc aatttcaaaa aacagcattt catgtttgat gaatattgtg actcgtgatt
    17581 cggagttggc aggagaacac cgtttattcg ggaaaagggg ctatgacaaa attttgttat
    17641 aatccttttt tttgtcttaa aaaagagaga aagtggttga aattacattt atcgtatata
    17701 aaacaatccg tgtatagatg ctgcattatg ttcaccacca tcaaaaaaat aagggactgt
    17761 gacaatacta ttgtcacaat cccttattac tgtgtattct attaaatcaa tcatctttct
    17821 catctgattc tttggttgct tgattcgctc ttgcataagc tgaagcggtg ttccagtaat
    17881 ctgtatagtt ttcatcggta ccgccaacgc caaatttaaa ggcgcttttc ttcggtccat
    17941 ttttcgccca tagcgattca actgtttttc ctggtgtttg gatggatttt ttattgacag
    18001 taacttttcc aggtgtttga ccagtaaatc cagatacttt tttcttcatc acatcagatg
    18061 ataattcgaa tttctcatca gtgccaaaaa tgtcaggttt tgcttggtaa gcttgattga
    18121 tcagattggc aagataatta gccgaacgta tccttgcttt gctgtccatt ccggtattgt
    18181 catcgtgccc tgcccagcta ctgatggtaa tagacggagt agagacaatt agccatgaat
    18241 ctcggtattc attggtagaa ccagtttttc cgacccaatc tgcttttcct agatttccgt
    18301 ttaagcttga gatggcatct ttgaatggtg tagtgatttt tgcattgatc acactgcgca
    18361 tcatgtcatt catgatcgat gccgttgctt ccgaatagat ccggacagag ttgctttcgt
    18421 gtttataaat tacatttcct gcgttatctg tgatggaatc gatgatatag ccttcttcat
    18481 agacgccgcc gtttgctaaa gcctgaaatc cattggtctg ttgaagcgtc gtgacatcta
    18541 ctgtacctaa aggagcagat tcaacgcccc aattgtcatt tgccgggtag ttcatctttg
    18601 ccaagtagtg ctcgtaagca tattgtttcg atccaccgga attcaacaca tcttgatata
    18661 agtgataagc cgggatattg ttggaccatt ctagtgactc acggacggtt tggaaggtgt
    18721 tcgatccttc gttagtagca ttgacgattt tctcgccagc attttctcct tcttgccaag
    18781 ttgttgcata atctgataca cgggattctg atccgataag ccccatgtcg attgcaggtc
    18841 cataaacaag aactggtttg attgatgagc cagcttgacg ttctgtatcg aaggcatggt
    18901 tattttgatt ctgactgtaa ttccgtccgc caacgaatcc gtagatgcgg ccagttctgt
    18961 tatccatcaa tacatttccg gtttctactt gactgccagc accatcatct aacatgtatc
    19021 cataattttc tacgccattt tgcaatgcag catagacatc tttatcgatt gtcgaatgga
    19081 ttgtatatcc tttattttgg atcgtttgct gtgccttttg ataataagcg tcactgaccg
    19141 atgaatcaga catatcagcg ttgtcttttt cagccaattg ttgtgcaatg attcttgttg
    19201 cttcattcat cacagtataa tacaagaatt ctctgtcagt ctgttctgcg atttgttgtg
    19261 gtagaaagtc ttttgtaagg tcataggctt ttgcttcttc gtattgttct ttcgtaattt
    19321 ggccttcacg atacatactg aataaaacaa aatcttttct ggcaaggccg gcagaaagat
    19381 cttcttttag cgcacctgtg ttcgtgtatg gactatacgt gatcgggctt tggggtaatc
    19441 cagcgatata agcagcttgc ggcagcgtca catcttttgc atctacacca aagattcctc
    19501 ttgcagcttc ctggactcca gcaatgtttt gtcccttatt attacgacca aatggtgaga
    19561 cattcaaata cgtagcaatg atctcatctt ttgaaaagta tttttctact tgtgcagaaa
    19621 gaatgatctc atttgcttta cgtttgaatg ttgtttcatc tgtaaggatc tgctgtttga
    19681 ctaattgctg tgtcaaagtt gatccaccag aagagccaat accagtagct tcagatacta
    19741 atgctcgtaa aacagcttta ggaacgtaac cttggtgttt atcgaagtat tcatcctctg
    19801 tgctgataat tgcagttttc aataaaggtg aaattttatc agatgaaata gtcgtgcgca
    19861 tcagatctgt ctggattttt gatatctctg tattatctgc ataaacaatc tttgacgttt
    19921 ctgtaatgtt tcctagttct gtctgcagtg cttttttagt cggcaattgt gtgtcttcga
    19981 cgagataggc aaaatagcca gcgcctattc caatacctag agctgcgaac atcaaaagaa
    20041 gaacagtaat aaaaacagtc aatgattgaa aaactctaaa aataatctta ggaacaaacc
    20101 atttttcttt ttttcttcta ttctgttttt ttcgagtatt tttgcgtggc aaaagggtca
    20161 cctcaactaa tggttttatt tcgctaatta tagcaaataa tagaacaaaa aaacagacaa
    20221 ggctgttttt ggcaggaatt tcttttttaa ag
//
LOCUS       DACCVZ010000051        20128 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.051, whole genome shotgun sequence.
ACCESSION   DACCVZ010000051 DACCVZ010000000
VERSION     DACCVZ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.051"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            133..636
                     /locus_tag="IVW63_001826"
     CDS             133..636
                     /locus_tag="IVW63_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAP7860099.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKEQIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCNLAEELEGTPIGEAASEIQHAFFNSFEEMVEH
                     VDDIVYYPDCDDMSDVAHYLIVEAGDFGEVPEQLKPYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPE"
     gene            763..1800
                     /locus_tag="IVW63_001827"
     CDS             763..1800
                     /locus_tag="IVW63_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860100.1"
                     /translation="MANIQTSFIDFHNSIRLDVEDNTLLKDYKDQVIDGLKDYLPDDV
                     KFETFLQGSYSVYTGIKSCDEKIDFDIDIAVAFEIDHTVYEDPREPKLWVKEALVEIF
                     PNAQVNLKVPCVTATFTGKKTKKNVHVDVAVYAKEDENYFLAKAKEFSAPENRCWEEA
                     DPKVLKEKINSHVADSDDRKQFRRCIRYLKRWKDNNFNQEYKPTGIGLTINVMDTFLV
                     NKSTDFLTRKVQYNDMECMKQIVSSLKDSFVYEYSETDGWHYRLHAYLPVKPNSDTYS
                     KMTVNQMSDFKNKLSKLYDDLIFAIDTEDEYEATKRLNNQFGEDFLIISEEEVTEKNL
                     RNAFVTDYPSA"
     gene            1815..3512
                     /locus_tag="IVW63_001828"
     CDS             1815..3512
                     /locus_tag="IVW63_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HAP7860101.1"
                     /translation="MDYTDILKEKLTDVVRLFDGNYYGDFSFATIGKLRLKIEIPKHF
                     PLVLPRIYIHNFDHLGLYLPHVEKDGLVCFSSDINYLVDEENSELVLLQCVNKTIKTI
                     EEGLKGLNKNDFRKEFVAFWDKQENQISLFYLCEPALFIKSVDTIMYGKSLVALDKEN
                     ELQLNAASRLFNGEKEDTHELDAYYVPIRNKNNIMPPKNNKAWSKKDILQIVKKNVTG
                     ANKRFFLKLEKRKNRHNVLLILDIPIEEKSNNVIIGFLFTKQSGSIKDYKGTPRTVLV
                     QRHDELYLVNRTSGENYGLGANIAIVGVGSVGSKIAENLGPLGVRKMTLIDNDCFQAE
                     NLYRNSLGADSLKNARSQNNFFKVDLMQEELEKKIPYLCVEVESMNVLDLISMQPGFF
                     KEYDYVFVCIGDTMASLALNNYFSKSSQKVFYSWLEPYGIGGHTLFINYSLNQKGCFN
                     CLYTDSNSKNRCSNRASLVKEGQIFERTLASCRSKFIPYNAIASTECAINAIKLFHKV
                     NQNNMTNSTLFSWIGDGSTFENLGYQYSDRNTFLNGVNKFEERFFSKYCKVCGELDD"
     gene            3505..3966
                     /locus_tag="IVW63_001829"
     CDS             3505..3966
                     /locus_tag="IVW63_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860102.1"
                     /translation="MIKFSCDRIVIEVRDEVLKIFEQYRQGKDDLPEAGGVLHGKRLK
                     NGSIIITDITTPQIGDIQKRLLFKKNREIHQQLSNEKWIESNKFSIALGEWHTHPEAV
                     PTPSNVDKKSWRLNVSKQHDDRVYVFIIVGFSDLRMWLLSKKSDIRQAIKL"
     gene            3979..4839
                     /locus_tag="IVW63_001830"
     CDS             3979..4839
                     /locus_tag="IVW63_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860103.1"
                     /translation="MKSQKNIWWWGFLVGKVMIPALLLISLPMITFFFTNKKMSKEAV
                     IFFFGDQKATFIETLVTSLQLNLNYIFSIIIVISLLNFFKKRNSGKVFNSNGNVYYNY
                     FYFVFWVAATLLGYDKIQIAGIPIHMQYKLVLSGIFSEVLPDIYDDHYDSDGTCKVSI
                     EKENFDDIDGYDSVNLLIIDTYDIKMSELSMENQTYPTIIVRGNSIDGVRKVNRSLIL
                     EIKKTMDEIQKSDFKKVFVASTSNPKNSINIINSSFRFFGRSRRFKLYVLQKDYASNG
                     KYSKKYRIFI"
     gene            4877..5266
                     /locus_tag="IVW63_001831"
     CDS             4877..5266
                     /locus_tag="IVW63_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP7860104.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLMFV
                     IVFAHVPPLSMIEGAFLKYLGIPIAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            5253..7700
                     /locus_tag="IVW63_001832"
     CDS             5253..7700
                     /locus_tag="IVW63_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP7860105.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDLQTDALVSMI
                     GDSQIDYRFFIGFKLISTDEEVNLKNLRKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVKRVTPSDLTYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPTRCLIEEKPRYLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAKSVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HKEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALASAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVIVELRKEDSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDKEDESNQKCMRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            7705..9813
                     /locus_tag="IVW63_001833"
     CDS             7705..9813
                     /locus_tag="IVW63_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP7860106.1"
                     /translation="MKKKLFRIFGIVLISLVTLIILLSLVGTVAEATGLVDDTVGAGN
                     LYSQYSLGNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEVGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMNMFNLQSNDSQSMGRRVMRKPQMLMNRTLR
                     QLNRNVGRTLAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEIPSDLNKEK
                     PIPNNKKQSRMNLAGRKVGKVLDTQALVKDKTKQVKDGVRNTPTNLKYNFHKGIEKTK
                     KAPEEFKRGLVQEKANRGELREKQQQRRDEKIAEKRKVLNEIGNPHGKRRENVPIKAK
                     VQSQKDRAPKRIVRANSNPEIKRKFASQEIISKGINQSSSKKNSFQQVKRRSTLSKRT
                     NRKVQKSLNPHPKPRSGEKK"
     gene            9810..10814
                     /locus_tag="IVW63_001834"
     CDS             9810..10814
                     /locus_tag="IVW63_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAP7860107.1"
                     /translation="MNVKKLSAISLTFLTISFMGILMCVGLLFGEDSEGSSSSGAPPG
                     GSSVSEEVLKHRAMVEKYAKESDITEYVPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNFGGGYLDYVAKNGKKHSFALA
                     ESFSKEKSCGQKIDYPNPIANKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSRPETGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            10833..11744
                     /locus_tag="IVW63_001835"
     CDS             10833..11744
                     /locus_tag="IVW63_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP7860108.1"
                     /translation="MKIKIERNQKEKSLKKKKERVVSVGKHRKMVLALWLLLSCSLTF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGIENFTKDFSKEYFSWKNNKEAIEKRMNNL
                     EQYLTEEGFALSQDMVRADIPTNSEVQSVKVLDVEKSSEEFVVSFLVEQKITEGKKAQ
                     SISSAYRVTIFEDENRNYIVTSLPTMIAKPDRAKYKTKQVENDSKIDAKTTEEIAEFL
                     ETFFKLYPSASEKELEYYVENDAMRPINIDLKFSKLEDPVYLQNGKKILVSTKIKYLD
                     NVSKTTSYFQYKLILQKNGNWKIIDVK"
     gene            11931..12218
                     /locus_tag="IVW63_001836"
                     /pseudo
     CDS             11931..12218
                     /locus_tag="IVW63_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(12406..12621)
                     /locus_tag="IVW63_001837"
     CDS             complement(12406..12621)
                     /locus_tag="IVW63_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860109.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(12880..13047)
                     /locus_tag="IVW63_001838"
     CDS             complement(12880..13047)
                     /locus_tag="IVW63_001838"
                     /inference="COORDINATES: protein motif:HMM:NF018933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7860110.1"
                     /translation="MGSECGHTDGKKSFTIREWTCPICRTHHDRNVNVSINILIKGYV
                     YKHCLRKHQEP"
     gene            complement(13392..14831)
                     /locus_tag="IVW63_001839"
                     /pseudo
     CDS             complement(13392..14831)
                     /locus_tag="IVW63_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172772.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(15379..16050)
                     /locus_tag="IVW63_001840"
     CDS             complement(15379..16050)
                     /locus_tag="IVW63_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HAP7860111.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRYLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCQCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEKWIAYITLK
                     KRGTI"
     gene            complement(16399..17850)
                     /locus_tag="IVW63_001841"
     CDS             complement(16399..17850)
                     /locus_tag="IVW63_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAP7860112.1"
                     /translation="MKKSLKLASAVILMSQLFIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTLSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSAESSTTSSSTSEITSSKVTRPNHIESSKKEAPKTEGQTKNFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            complement(17962..19305)
                     /locus_tag="IVW63_001842"
     CDS             complement(17962..19305)
                     /locus_tag="IVW63_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP7860113.1"
                     /translation="MKKIVIIGSNHSGLAAARFLNLCDSNYEVILIDKKSEISYLECG
                     TSLFIKREVSNLEDLFYQNRRELNSKIKKLFLETAVDKIDIQNKKIICVKKDGTRFSQ
                     EYDKLILATGSKQIMLDVPGNNLANIFSIKNFPNAKEIFKALDDNTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGKKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHIDNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPVFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            complement(19439..>20128)
                     /locus_tag="IVW63_001843"
     CDS             complement(19439..>20128)
                     /locus_tag="IVW63_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP7860114.1"
                     /translation="NPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTA
                     GNKKGIVVVTYPDGSKEEVEVTISVEDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTV
                     TLPNGSQYHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNEKDSE
                     KAVSKDNKTDNQGSKQNKNRGKSSPQKQSSKAYPKTGEIDSNIFTISGGLILLGTLGL
                     LGYKNRKKENE"
BASE COUNT         6498 a         3414 c         3743 g         6473 t
ORIGIN      
        1 gagttttcca aactgattgg cttcttggtg attgctttga ttgcggtagg tctggtcttt
       61 aatgcttctg gtgtgaagga tgtcctactc aatttgttta accgaattgt cggtgcctga
      121 gggggaatca caatggaaca gatgcgtgtt tatattgcga accttggaaa atacaatgaa
      181 ggtgagttgg tgggggcatg gtttacccca cctgtcgatt ttgatgaagt gaaagaacag
      241 attggattaa atgacgaata tgaagagtac gcgattcatg attatgaact gccttttgag
      301 attgatgagt atacgccaat tgaagagatt aatcggttgt gtaacttagc ggaggaacta
      361 gaaggaacgc caattggtga agctgcttct gagattcaac acgctttctt caattctttc
      421 gaggaaatgg tagagcatgt ggatgatatt gtctattatc cagattgcga tgatatgagt
      481 gatgtggcgc attacttgat tgtagaagct ggtgattttg gcgaagttcc agaacaattg
      541 aagccgtata ttgattttga tgcttgcggt cgagatttgg agattggagg aaattatttg
      601 gttactagtc gtggagtttt tgagtatcca gaatgaatca aacactatat atagtgtttg
      661 attagtatat gtaagcaaaa aaacacaata tatagagtgc aaactgaagg gtaatgtgat
      721 ataatatttg ccgaagaaat atttttgaaa tgaggtaata ttatggcaaa tattcaaaca
      781 agttttattg atttccataa ttcaattaga ttggacgtag aagacaatac gctacttaag
      841 gactataaag accaagtaat tgatggatta aaagattact tacctgatga tgtgaagttt
      901 gaaacttttt tacagggaag ctattctgtt tataccggaa taaaaagctg tgatgaaaaa
      961 attgattttg acatcgatat tgcagttgct ttcgaaattg atcatactgt ttatgaagat
     1021 ccaagggagc ctaaactgtg ggtaaaagag gcgctagttg aaatttttcc taatgctcaa
     1081 gttaatttaa aagtaccttg tgtaactgct acatttactg gaaaaaagac aaaaaaaaat
     1141 gtgcacgttg atgttgcggt ttatgctaaa gaagatgaaa attatttctt agcaaaagca
     1201 aaagaattca gtgctcccga aaaccgatgc tgggaggaag cggatcccaa agtattaaaa
     1261 gagaaaatta atagtcatgt agcagattca gatgatcgaa aacaatttcg aagatgtatt
     1321 cgctatttaa aaagatggaa agataacaat tttaaccaag aatataaacc aacaggaatt
     1381 ggacttacaa ttaatgtgat ggatacgttc ctagttaata agtccactga ttttttaact
     1441 agaaaagttc agtataatga tatggaatgt atgaagcaga ttgtttcttc gctgaaagat
     1501 tcatttgtgt atgagtacag tgaaacagat ggttggcatt atcgtctaca tgcatatctt
     1561 ccagtgaagc ctaacagtga cacctattca aaaatgacag tgaatcagat gagtgatttt
     1621 aaaaacaaac tttctaaatt atatgatgat ttgattttcg ctatcgatac tgaagatgag
     1681 tatgaagcta caaaacgatt aaataatcaa tttggggagg attttttaat tatttcagaa
     1741 gaagaagtta cagaaaaaaa cttaagaaat gcatttgtta cagactatcc gagtgcttag
     1801 gttggtgtta aagattggat tatactgata ttttaaaaga aaagctaaca gatgttgtgc
     1861 gtttattcga tggtaattac tatggggatt tttcatttgc tacaattgga aagttgcgtt
     1921 taaaaattga aataccaaaa cattttccat tggtacttcc taggatttac attcataatt
     1981 ttgatcattt aggactttac ctaccacatg tagaaaaaga tgggttggta tgtttttctt
     2041 cagatataaa ttatttagta gatgaagaaa attcagaatt ggttttattg cagtgtgtta
     2101 ataaaactat aaaaacaatt gaggaaggtt tgaaagggtt aaataaaaat gattttcgaa
     2161 aagagtttgt tgctttttgg gacaaacaag agaatcaaat ttcgttattc tacctttgtg
     2221 aaccagcgtt gtttatcaag tcagttgata caataatgta cggtaagtct ttggttgctt
     2281 tggataaaga gaacgaatta caattaaatg cagcgagtag attgtttaat ggagagaaag
     2341 aagatactca tgaattagat gcatactatg ttccaattag aaacaagaat aatattatgc
     2401 ccccgaagaa taataaagca tggtcaaaga aggatatttt acaaatagta aaaaaaaatg
     2461 taacaggtgc aaataaaaga ttttttttaa aacttgaaaa aagaaagaat agacataatg
     2521 ttttacttat tctagatatc ccaattgaag aaaagtcaaa taatgtcata attggatttc
     2581 tttttacaaa acaatctgga tctataaaag attataaggg tacgcctagg actgtattag
     2641 ttcagcgtca tgatgaatta tatttggtga atagaacgag cggagaaaac tatggattgg
     2701 gtgctaatat agctattgtt ggggtagggt cagttggcag taaaattgct gaaaatcttg
     2761 gtccattagg tgtgagaaag atgacactca tagacaatga ttgttttcaa gctgaaaatt
     2821 tgtatcgaaa ttcacttggt gcagatagtt taaaaaatgc ccgatctcag aataattttt
     2881 ttaaagttga tttaatgcag gaggagctcg aaaaaaaaat cccatacctt tgtgttgaag
     2941 tggagtcaat gaacgtttta gacttaatta gtatgcaacc tggttttttc aaggaatatg
     3001 actatgtttt tgtttgcata ggagatacaa tggcaagcct ggctttaaat aattattttt
     3061 ccaaaagtag tcaaaaagtt ttctattctt ggctggagcc atatggcatt gggggacaca
     3121 ctctatttat aaattattct ctaaatcaaa aaggttgttt caattgtctt tatacagatt
     3181 caaactctaa aaataggtgt tcaaatagag cttctctggt aaaagaagga caaatttttg
     3241 aaaggacttt agcgagttgc cgctcaaaat ttataccata taatgctatt gcctcgacgg
     3301 aatgtgcaat taatgcaata aaacttttcc ataaagtcaa tcaaaataat atgaccaata
     3361 gtactctttt ttcatggata ggagatggga gtacttttga gaatttagga tatcaatata
     3421 gcgacagaaa tacttttctt aatggagtca ataagtttga agaaagattc ttttctaaat
     3481 attgcaaagt atgtggggag ttagatgatt aaattttcgt gtgaccgtat tgtcattgaa
     3541 gtaagggatg aagttcttaa gatatttgaa caatatcggc agggaaagga tgacttgcct
     3601 gaagctggag gagttcttca tggaaaaaga cttaagaatg ggagcataat aattaccgat
     3661 ataacaacac ctcaaatagg agatatacaa aaaagattac tctttaaaaa aaaccgagaa
     3721 attcatcaac agctttctaa tgagaaatgg atagaatcaa ataagttttc tattgcattg
     3781 ggagaatggc atactcatcc tgaagctgta ccaactccat caaatgttga taagaaaagc
     3841 tggagactga acgtgagcaa gcaacatgat gatagagttt atgtttttat tatcgttgga
     3901 ttttctgatt tgagaatgtg gttactgtca aaaaaatcag atattaggca ggctataaaa
     3961 ctataaagga gtgattaggt gaaatcacaa aagaatattt ggtggtgggg gtttttagta
     4021 ggaaaggtaa tgataccagc ccttctctta atttctctac cgatgattac ttttttcttt
     4081 accaataaaa aaatgagtaa agaagccgtg atttttttct ttggagacca aaaagctacc
     4141 tttattgaaa cgttagtaac atctcttcag cttaatttga attacatttt ttcaattatt
     4201 attgttatat cgttattgaa tttttttaaa aaaagaaatt caggaaaggt gtttaactct
     4261 aatggaaatg tgtactacaa ctatttttat tttgtatttt gggtagcagc aactttactt
     4321 ggttatgata aaattcagat tgcaggaatt cctatacaca tgcaatataa gttggttttg
     4381 agtggaattt tttctgaggt gttgccagat atatacgatg atcattacga cagtgatgga
     4441 acatgtaaag taagcattga aaaagaaaat ttcgatgaca tcgatggata tgactctgtg
     4501 aacttactga ttattgatac ttacgatata aaaatgagtg aattatctat ggaaaatcaa
     4561 acatatccta cgataattgt tagagggaat tcaatagatg gagttcgtaa agttaataga
     4621 tctttaatct tggaaataaa aaaaacaatg gatgaaattc aaaaaagtga ctttaaaaaa
     4681 gtatttgttg cttcaacatc taatccaaaa aatagtatca atattattaa ttcatcgttt
     4741 agatttttcg gtcgatcacg taggtttaaa ctttatgttc ttcaaaagga ttatgcaagc
     4801 aatggaaagt atagtaagaa atatagaatt tttatttaag aaggaatttt tccttctttt
     4861 tattttggag gaaactatga aaaaaataaa aagctacacc agtatttggg cagttgaaaa
     4921 agtcatttat gcgattaatg actttcagct gccttttcct gtgaccttta accagatggc
     4981 ttggtttgtt ttatccttga tgtttgtcat tgtatttgcc catgtgcctc cgctatccat
     5041 gatagagggg gcttttttaa aatacttggg cattccgata gcggtcactt ggttcatgtc
     5101 gcaaaagacc tttgacggta agaaaccatt gggattttta cgatccttta tcagctatca
     5161 cttacggttt aaggtcactt ttgcaggaaa gaaagttaaa gaacagaaga aacgatggga
     5221 cgaaccaatc accttggtaa ggagtgtgaa ttatgtaccc gattaagtat attgaaaata
     5281 atcttgtctt taaccaagaa ggcgagtgtt ttgcttacta tgaattagtg ccttacaatt
     5341 actccttttt gtcacctgaa cagaagtatc aagtacatga taactttcgc caattaattg
     5401 cgcaaaatcg tgaaggtaag atccatgcct tacaaattgc cacagaaagt agtattcgtg
     5461 ccacacaaga acgttcgaaa aaggaaatta ccggtagact caaagaagta gcaaagcaac
     5521 gaattgattt acagacagat gcattagtat ccatgattgg cgatagtcag attgattatc
     5581 gcttctttat tggctttaaa ctgatttcga cagatgaaga ggtcaatcta aagaatctca
     5641 ggaaatcttt cttttctgga cttcaagaat ttgtctatgg agtgaatcat catttgatgg
     5701 gtgattttgt ttccttatcc aatgaagaaa ttcgtcgcta taccaagctt gaaaaactaa
     5761 tggaaagtaa attggctcga agatttaaag tcaaacgagt aacgccgagt gacttgacgt
     5821 atttaattga acatatctat ggtgaaaaag gcacaccgtt tgaagaatat gaattccagc
     5881 taccaaagaa aaagctgaaa tcagaaacgc tggtgaaacg ttacgactta ttacgtccca
     5941 ctcgttgttt gattgaagaa aagcctcggt acttacggat ggaacatgaa aatcatgagt
     6001 cttatgtagc gtacttaaca attaatacca ttgtagggga aatggagttt ccttcctcgg
     6061 aacttttcta ttaccagcaa caacaattta cgtttccgat tgatacttca atgaatgtgg
     6121 aaattgtgac gaataaaaag gccctagcta ccgttcgtaa taagaaaaag gaattaaaag
     6181 atttagacaa ccatgcctat caatctgata atgaaacgaa ctccaatgta ttagatgctt
     6241 tggattccgt ggatgaattg gaaaccacct tggatcagtc gaaagaatcc atgtataaac
     6301 taagctatgt ggttcgagtg agtgctaaat cagtggatga attaaaacgc cgctgtgatg
     6361 aagtgctcga tttttatgac gataccaatg taaaactagt ccggcccttt ggcgatatga
     6421 tgggtctaca caaagaattc ttaccctcaa gtaagcgata catgaatgac tatattcaat
     6481 atgttacgtc tgactttttg gcgggacttg gttttggggc tactcaaatg ctaggagaat
     6541 tagaaggcat ttactttggc tataacgtag atacggggcg caatgtttac ctgaaaccgg
     6601 cattggcatc acaaggggtc aaaggctcag taaccaatgc tttggcatct gctttccttg
     6661 gttcgttagg tggggggaaa tcttttagca acaatctctt agtctattat gccgtccttt
     6721 ttggtgggca agctgtgatt gtcgatccaa aaggagaaag aggcggttgg aaagaaacgt
     6781 tgccagaaat tgcggatgaa attaatattc ttaacttgac cagtaagcca gaaaatcaag
     6841 gcttacttga tccctatgtg attatgaaga aaaagaaaga ctcagaaagt ttggcgattg
     6901 atatcctgac ctttttaaca gggatttcca gtcgggatgg ggagaagttc cctgtgttac
     6961 gcaaagccat tcgaacggtt acccaaagtg atcagcgagg attattacaa gtaatcgttg
     7021 aattgcgtaa agaggactca ccagtcgcgg aaaatatcgc ggatcacatc gagtccttta
     7081 ccgattatga ttttgcccat ttgcttttct cagatggttc gattacccag tcgattagtt
     7141 tagataagca gttaaatatc attcaagtag cggatttggt tttaccagat gcagaaacca
     7201 cttttgaaga atataccacc atggaattgc tgagtgtttc catgctaatt gttatttcca
     7261 cttttgcctt ggactttatc catagcaacc gagaaatttt caagattgtg gacctggatg
     7321 aggcttggag ttttcttcaa gtagctcaag gaaaaacgtt atcgaataaa ttagtgcgtg
     7381 ctggtcgggc catgaatgcc ggtgtttact tcgtcacgca aaacagtgat gacttgttgg
     7441 atgaacgttt gaagaataat attgggctaa agtttgcatt tcgcagtacc gatattcatg
     7501 aaatcaagaa aaccttggaa ttctttggat tagataaaga agatgaaagt aatcaaaaat
     7561 gcatgcgaga tttggaaaat gggcaatgct tgatgcagga tttgtatggt cgagtaggtg
     7621 tggtccaagt tcatccagtc tttgaagaac ttttccatgc ttttgatacc cgtccgccag
     7681 ttcaagagag aatggagtga ggagatgaaa aagaaacttt ttcgtatctt tggaattgtt
     7741 ttaatcagtt tggtcactct gataatactt ttgagcttag ttggaacggt agctgaggca
     7801 acaggtctgg ttgatgatac agttggagcc ggaaatcttt attcccaata ttcacttggt
     7861 aactatcagt tggatttctt tgtggatagt tcgtgggatt ggctgccttg gaattggggt
     7921 gatggcctag ggaagagcgt aatgtatgga ctttatgcca ttactaattt tatttggaca
     7981 gttagtctct acttatcaaa tgccacgggc tacgtggttc aagaagccta taagctggat
     8041 ttcatttcag atacggctga aagtattggg aagaatatcc aaaccttagc cggcattacc
     8101 gaaaatggac tccagacctc gggcttttac tttgggtttc tattattgat gattttagct
     8161 ctaggagttt atgtggcgta tacaggatta ttaaaacgag aaactaccaa agcagtccgg
     8221 gctgtcatta attttgtgat gatttttcta ctttcgggtt cgttcattgc gtatgcgccc
     8281 acctatatca caaaaatcaa tgattttagc tcagatgtca gcgaagcggc tcttagcctt
     8341 ggaaccgaga ttgtcgtgcc gaattcagaa agccaaggaa aggacagtgt ggatttaatc
     8401 cgagatagct tgttttccat tcaagtccaa caaccgtggt tactcttgca atttgatgat
     8461 tccaatatag aagaagttgg cgaagatcgt gttaacaaaa tcctgtctgt aagtccagat
     8521 gaaaataaag gcaaggatcg ggaagaagcg gtcaaagcgg agattgaaga taatgacaat
     8581 gcgaatctca gtattaccaa gaccatgaac cgcttaggga ccgtggtctt tttggtgttg
     8641 ttcaatattg gcatatcctt ctttgtcttt ctcctaacag ggattatgtt gttctcgcaa
     8701 attctcttta ttatctttgc gatgtttttg ccgattagtt tcttattgtc catgttgccg
     8761 acttatgaga gtttgggcaa gaaggcgatt attcgcttgt tcaatacgat tatgatgcga
     8821 gcaggagtta ctttggtgat tacgactgca tttagcatct ccacgatgtt tttcaatatt
     8881 tcggcaacct atccattttt catggttgct tttctgcaaa ttgtgacctt tgccggtatc
     8941 tatttcaaat tgggcgacat tatgaatatg ttcaatctcc agagtaatga tagccaatca
     9001 atgggaagac gggtcatgcg aaaaccgcaa atgttaatga atcgaacatt gcggcaactc
     9061 aatcgaaatg tgggacggac tttggctttt ggtggtggtg cagcagttgg aaataagttg
     9121 gcaaaggaac aatcaaaatc caaatttaag ccatccggtt cttctctacg aaagaattca
     9181 cgattaccga acgatcacga gataccatct gacttgaata aggaaaagcc aattccaaat
     9241 aataagaaac aatcccgaat gaatttggcc gggagaaaag tcggcaaggt tctggatacc
     9301 caagctttgg tgaaagataa gaccaaacaa gtaaaggatg gagtacggaa tacgccaacc
     9361 aacttgaaat acaacttcca taaaggaatt gaaaaaacga aaaaagcacc ggaagagttt
     9421 aagcgaggac tggtccaaga aaaagcaaat cgaggagagt tgcgagaaaa acaacaacaa
     9481 cgtagagacg aaaaaatagc tgaaaagcgc aaagtattga acgaaatagg gaatcctcat
     9541 gggaaaagaa gggaaaatgt tccgataaaa gcaaaggtcc aatctcaaaa ggatagagca
     9601 ccaaagcgga ttgtgagagc aaattcgaat cccgaaatca aacgaaaatt cgctagccaa
     9661 gaaatcattt caaaaggaat aaaccaatcc tcaagtaaga aaaattcttt tcaacaagtg
     9721 aaacggcggt ctactctgtc caaacgaacc aatcgaaaag tacaaaaaag tttgaaccct
     9781 catcccaaac caaggtcagg tgagaaaaaa tgaacgtaaa gaaattaagt gccatttcgt
     9841 taactttcct aacaatctct tttatgggta tcttgatgtg tgtgggctta ttgtttggtg
     9901 aagacagtga aggaagtagt agttcaggtg ctcctcctgg ggggagtagt gtctcagaag
     9961 aggttttgaa acaccgtgca atggtggaaa aatatgccaa agaatcggat ataacagagt
    10021 atgttccgat tcttttagcg attattcaag tggaatctgg tggcacaatg gaagatgtga
    10081 tgcaaagttc tgagtcagcc ggtttaccac cgaattcatt aagtaccgag gcatccatca
    10141 aacaaggatg tctctatttt gcgtctttgg ttaagcgttc caaagaatta ggttgtgatc
    10201 aagatagtat cattcaggcc tataactttg gcggtggtta tttggactat gtggcaaaaa
    10261 acgggaagaa gcatagtttt gctttagctg aatctttttc aaaggaaaaa tcttgcggtc
    10321 aaaaaatcga ttaccctaat cccatcgcga ataaggaaaa tggtggatgg cgctataact
    10381 atggcaatat gttttattgc ttattggtga agcaatacct aactacaaca cagtttgacg
    10441 ataaaacagt ccaagggatt tttgacgagg cgtttaagta tgaaggaacg gcttatgtat
    10501 ttggtgggtc aagacccgaa acaggatttg attgtagtgg cttgactcaa tggtgttatg
    10561 ccaaagttgg tctgaaactt cctcgggtgg ctcaagatca gtatgatgcc atgacccata
    10621 ttgacctaaa agatgccaaa ccaggggatt tggttttctt tcattcgact tatgatgccg
    10681 gtacttatgt gacccatgtc ggtatttatg caggggagaa tcgcatgttt catgcaggag
    10741 atccagtagg ctggacgaat ctaacagaaa gctattggca gcagcatctt atcggtgctg
    10801 gacggtacaa ataagagaaa agaggaaaaa gaatgaagat aaaaattgaa cggaatcaaa
    10861 aggaaaagag cctaaaaaag aaaaaagaac gagtcgtatc cgtgggtaag catcgaaaaa
    10921 tggtgcttgc cctttggctt ttattatctt gtagtcttac ttttggcgtt tataaaaatt
    10981 tcaccgccat tgatcaacat acaactcatg aaaaagtggt tattaaagag aaagtagtga
    11041 atacttctgg tattgaaaac tttacgaagg atttttcgaa agaatatttt tcgtggaaaa
    11101 ataacaaaga agcaattgaa aagagaatga acaacctcga acagtacctt acagaagaag
    11161 gtttcgcttt aagtcaagat atggttcgag cagatattcc cactaattcc gaagttcagt
    11221 cagtaaaagt cttagatgtt gaaaagagct cggaggaatt tgtcgtttca tttttagtgg
    11281 agcaaaagat tacagaggga aaaaaggcac aatcgatttc ttctgcatac cgagtgacga
    11341 tctttgaaga tgaaaacagg aattatatag taacgagttt gccaactatg attgcaaaac
    11401 ctgatagggc aaaatacaag acaaaacaag tagaaaatga ttcgaaaatt gatgccaaaa
    11461 ctacagaaga aatcgctgag tttttggaaa cgttctttaa attatatcca tcagcttctg
    11521 aaaaagaatt ggagtattat gttgaaaatg atgcgatgcg accaatcaat attgacttaa
    11581 agttttcgaa gttagaggat ccagtttacc tacaaaacgg aaaaaaaatt ctagtgagta
    11641 caaagataaa ataccttgat aatgtatcaa aaaccactag ctactttcag tacaaattaa
    11701 tattacaaaa aaatggaaac tggaaaatca ttgatgttaa ataataatga ctcaatctaa
    11761 atttatgaga agttataagt agtttaactt atttcaggca gaagtcgccc atcctctata
    11821 ggtgggtgat gaatgccgtt cggtaactcg aaaaccgaca attaagacat agtgcctttt
    11881 tattttaatc catgtcataa tcagtctata taagaaatgg ttgatatacc atggaattag
    11941 atacaaataa tcattcatta tttcttcttt gttaccacct tattttagta gtgaaacatt
    12001 gtaaacatct cattgatgat gtaatgttag cttatgcaaa aaactatctt tgaaagaata
    12061 tcagaatcac atcacattac cttagttgag tgaaatcgtg ataaagacta ctttcatatt
    12121 atgctcaaag cacaacctaa aaccgaatta acaaaattca gcaatgccta agctcatgtc
    12181 tgataaaatg agactttcta agggtcaaaa atttcctttg aatacgatca ttagcttaga
    12241 taaaagtaaa aaccttagaa ctacggggat agcttggtta ataagagata tcgctgttaa
    12301 taaagacata agcttgcaag tatgctctat tcccaagaat ctcccacttc aagcactaag
    12361 gatcgttaaa ttcagctaag tggcaagtag ttcactagac gataattatc tccatatttc
    12421 aatctcagct tttccatttt tcatagcaaa ttccgttatt tttatagcat ctaaaagatt
    12481 cagcttttcc actgatcttt caccactttt cagctttttt attgtgctta aattgatacc
    12541 agtacctttt gatattgaat tggaagtaaa atcattaagg gtttttttta ttaaattcat
    12601 atccgcaatt ccagcgttca taagaatgaa gattctcctc tcatagacta ctttgaaaat
    12661 ggtactacag tggctgttta tatatttcag taggttactg tagtggtcat tttattataa
    12721 ttagaaaagg aacctaaatc aaaaatgcta aagaaaattt tcatagtatt aaacctatca
    12781 tgactaaagc cacggaattc ttgataaaag agtatacttg caagcctatg tctttactaa
    12841 cagcgatatc tcttattaac caatctatcc ccgttgttcc taaggttctt gatgttttct
    12901 aaggcaatgc ttgtatacat agcccttgat caaaatattg atactaacgt tgacgtttcg
    12961 atcatgatgt gtacggcaaa taggacaagt ccattctcga attgtgaatg acttcttacc
    13021 atctgtgtgt ccacattctg aaccaatttg actagacgga aatcatttat ctatcttgat
    13081 gatttttttg acagaagtat cgaaaatctt tacataatct gggtgttgca ttcttatgca
    13141 gatgagagcg ttagctccgt attcataacc agttgcctct aaaacgtagt ccatcggtgg
    13201 atacctagct tgcggttgcc agtggctttc gcagtcttct tgtaatcaaa tcgagcatct
    13261 aattgagtac tagtattttg aagataatac ttgagttttt cggttttcag aagttcactt
    13321 catcttccat catccatgga aatcccactc acccatacgc aggcctccaa aaattcttca
    13381 acaatggttt ttcagacatt tttctgaata cctccttgtt ttttgatacg ccagatagtc
    13441 aggaaaaagg caacaaaaca caaaacaaag ctgcctaaaa aggtaatctt cattccatat
    13501 aaaaagacat ccggccgatc tgcgatatag ttagttactc gttggcccat cttagcagac
    13561 atcgcttgat ataagaccgt cgtagaaagc gaaatcccga tgaccatccc caaatttcgg
    13621 gcaaaggaat tcatggagcc tgccagtccc aaattttcga tagtgacaga actcataacc
    13681 atcgtattat ttggggactg gaacaaggca ttgccggcac ccatgatggc agtagcgaca
    13741 atgtacagcc acaaaggaga gtccactgac aaaaacatat acatgacttg ggttaccgac
    13801 aataaaccca agcctactaa tacaaaaatc tccgggccaa cccggtcggt caggtatccg
    13861 cttaaaggcg ccccgacgac catcatcaag ggaaagacca tcatcaacag tccggcatag
    13921 ctaggactca acccgcgagc attttgcaga taaaaaggaa tcactacatt aacaaagaag
    13981 ttggaagaaa aaatcaacaa ggctgtaatc aagctcatgg taaaaatctt gttcttaaaa
    14041 ataccgaaag aaatcaatgg agaggctgct ttcttttcaa cttttaaaaa gctgacaaag
    14101 gcaatcactg aaattacgaa cagtacaagg gggactggat ggaaaaagcc actttcttgc
    14161 cccaaaaaga ttgttccaaa aaggctgata atcgtagccg caatggcagc aaagccccct
    14221 ccatcgattg tatggccgct catggtgata tcttttggta agaatttttc agcaatcaac
    14281 atcgttacga ttcccaccgg tacattgatc caaaaaatgt acgcccaaga aaattgggac
    14341 aaaatcaagc cgccaagacc tggtccagca atcgagccta atgaaacaag cgcaccgatt
    14401 gctcccaatg cccgaccacg ttcatgtatg ggaaagactt ccgtgatgat tccggcattt
    14461 gtagccatag tcatactagc accaatggct tgtaccaccc gtgcgaacaa ttaaatacct
    14521 agcgaatgat tgaacccaca caacagcgag cccaagacaa agatcagcgt accaatccga
    14581 aatactttga ttttcccaca gctatcgcca attttaccaa acagcaacaa acaagaacag
    14641 acaatcatca gataaacgga cactacccat tccgcttgat tcattggtat gcccatatca
    14701 tctgagatgg taggtagtgc aatattgaca atactgccat ccaatgtgga catgaaggta
    14761 aacatagata tagcaatcaa aatccaccag cgattttttt ggacttttgc atcttcttga
    14821 taactatgca taataggatt tcctttctaa tgatcgtgta gctaagaaca atataaccta
    14881 tgtctactgc ccaacaactt ctcgcgactc tagccatagg aagcttgagt aatttcgatt
    14941 tgttattctc atgtaaccat gtaagtttga gatgctttat ttgaacttac tctatagtaa
    15001 ctagtgataa ttcgctttac tttcttctag caatttctaa aagtcgactt cattgttctt
    15061 cagattaata gtgtgagcta tctcgtgaga cgtaagaaaa tttccattct actttttccc
    15121 aattttttca tatttatggt gttgcaccta tttgttttcc aatttgcttt tcaaatacat
    15181 tgctatgata ttcaattcca taggattata ctaaatgtca atagtatgaa taatatatta
    15241 tagatgttta tatatcactg ttaattatta tccacaataa ttaatgatta cctcgatatt
    15301 tgtcaatcaa aggttgaaac aatttatttt cagcatcttt tctaacttga gctgcactct
    15361 taatagaatc atacgatcct aaatagtacc tctttttttt aaagttatat acgcaatcca
    15421 tttctcttta gaacgataaa ctcccttaac accacttgta ttatttttcg gtaattttga
    15481 cgttagacac tctattactg tcccttcaac acatgtcctt gtttcttgcc tttttaaaca
    15541 tccacaactt tgagtatgtc caaaaaataa gttactataa cttatctcac acatactgcc
    15601 acactcacat tgacaaaccc attttgtttt ccatgaacag ttattgtcca aaggatactt
    15661 tgcagtaagt aatccgaatt ttttattttc aatgtgatgc ttttttgatt tcaaacatcc
    15721 acagcttttt acatcacctt ttagaagtcg ctttgccgat actaactttt ttctcccaca
    15781 cagacattga cattcccaaa caacagttcc ttcacttcgc agtttagttg gcttgattgc
    15841 aactaactta ccaaaagttt tatttgtcaa atttttatat ttatgcctat ttttataatt
    15901 tccacatcca caacttttgg ttctacctga tagtaagttt gatcgatata caatcgtttc
    15961 attcccacag tcacataggt aacgatattt tttatatcca ttatgagtaa tctcctcaac
    16021 aacagtaagg tgaccatatc tttccttcac tgcacctacc ctcccaagaa agaagtacca
    16081 tataatttca attaactttt aataaatcag aaaaaaatat tttcaatttt tcttagtctg
    16141 attttatgac taatttataa tacaagactg aacgatacgt acacgaaatc ctcaagatag
    16201 ataaattgtt ttcatctagt aaaacctgct caaaatatga gcataaagac ggcaataata
    16261 cactcgatat tcgataatgg acttgtttta tttgtcaaac tcatcgtaat cgagatatca
    16321 attccagtct caatatcctg atcaaaggtc taagaatcca accattttct tgttactttg
    16381 tcagattgat tacctttttt agtctccgaa taataaggtt ttcggatcaa ctaacatgct
    16441 ctgagaaaga ctactatctt tgcaaatttc caaatgaagg tgtgggccag tactattccc
    16501 agtacttcct acatagccaa ttatttgtcc ttgcaaaaca ttatctccag tttttactag
    16561 gtattgttgc tggtgagcat ataacgcggt tgatccatct tcgtgttgta tcaccacgta
    16621 atttccccaa gagtagtgaa actctgcttt aacaacctta ccagctttaa ctgcatgaat
    16681 cggctcaccc tgtgtagctg ccatatcaag tcctcggtga aattcatttc cacgatttcc
    16741 aaacaaactg gttattgaat aattatgaat aggcacttgg tatccagtct tactcatttg
    16801 tggaccttta acttctttat catagttggt taaatcatag gttttaatta attcatttag
    16861 cttcaaatag tattgtgtat ctgttgcata ccgtcctgta aggaatttag ttgcttctcg
    16921 atatgtttta ctattagctt ttaatgctcc tgcataaaaa tctttatttc cactaattcc
    16981 cttagttaat aatttggcat aatcttcaaa actttcctca tagttttcat acactctaaa
    17041 ttttgattgg gtcgtataaa gcgttccatt acccaaatct tcgtttgtta ccataatgac
    17101 aaagtttcca ttataagttc cttttatccc aaataaattg taattcggtg cctgagctaa
    17161 ctggctttga ccactggcag attctaagat cgcttgtgca atcataacag aagcatataa
    17221 atcatatttc tgaccaattt ttctcgcaga ctcaccaatt ttcataataa aattttctac
    17281 agattcattt ttgtcaaaat gaatttcttc attaccagat agtattggtt gtgattggaa
    17341 agattctgtt gattctattt gctgtggtgt cgaaaaattt tttgtttgtc cttccgtttt
    17401 tggcgcttcc ttttttgaag actctatatg gtttggtctt gtcactttcg aagaagttat
    17461 ttcacttgta ctacttgaag ttgttgaaga ttcggcactt gaaatcgtac tactttcact
    17521 tgacgaagtt gttgaagact cggcatttga agtcgtacta ctttcacttg acgaagttgt
    17581 tgaagactcg gcatttgaag tcgtactact ttcacttgat gaagttgttg aagactcagc
    17641 atttgaagtc gtactacttt cacttgataa agttgtcaaa agttcactac tctctgctgt
    17701 tacatcggaa ttactcattt cagtcgtctc ggttctttct tttgcaattt tgtatgttga
    17761 attttcgctt gccaacacat ggaaaggtgt tgctataaag agttgggaca ttaatataac
    17821 tgctgatgca agttttaaag attttttcat ttgatttacc tctctttttt ctctttaata
    17881 gtgttttcta ttaaaaatta tgataaatat tttcaatgaa ttgagtaata cagtatattt
    17941 cttgatttca tttagtaacg attatgtttc aatgtttaat cctgttactg cctttaaaat
    18001 aaaattatag ggttggctaa aactaggatg aaataaataa tctaacattt tcaatttgtc
    18061 taatgtaatt tgttcttcta tagcaagaga aaacattgat aatagtccag ataaatcttc
    18121 ttgactacaa agttgtacac ctactattct ctttgtattt ttttcaaagc taattcttaa
    18181 ttttacacga ctattttttc tcaaaaaaac aggtctaatg aaatcttcta tttctatata
    18241 atctatagac tcacttaata atcgtgctgt ttttaaattc aaacctgctg cgtaaaaatt
    18301 gtaattaaat atagaaaagc catttgtaaa ttgggaacca gaaggtgtaa aatcttgatt
    18361 gtcaatatgt tgagttgcaa tataagctgt tcttagagca ttagaaatag aaaaatcaac
    18421 actacttcta ttaatggacg taaaaaaagt tgtagcacaa tccccaatag catatatatc
    18481 ttttatattt gtttgctggt attcattagt tagatatgct ccactaacat ctctcaagag
    18541 ttcctttttg ccaattggac tattagatag aaatcctata gcttgtacga ccatatccat
    18601 agagtattgg gtaccacttg tagtgactat tttttcaatc ttttttcttc ctaaatattt
    18661 tttaggactt tctgatagac aaagatgtat tccatttttt gatagtattt cttcaacttt
    18721 atctgaaaaa ctacggtcgt aataagtcga caacactcta tctgcaacat cgaaaagata
    18781 tacttctttc cctctttttc ttatggcttc agcaatttca actccaatat atcctgctcc
    18841 aataattcct acttttttaa tagtattatc atctaaagct ttaaaaatct ctttagcatt
    18901 tggaaaattc tttatcgaaa aaatattagc taaattattc cccggtacat ctaacataat
    18961 ttgctttgaa cctgtagcta gtataagttt gtcatattct tgggaaaatc ttgtgccatc
    19021 tttttttaca caaataatct ttttattttg aatatcaatt ttgtcaactg ctgtctccaa
    19081 aaacaacttt tttatcttag aatttagttc tcttctattt tgataaaaaa gatcttctaa
    19141 attgctaact tctcttttta tgaacaacga tgtcccacat tctaagtaac taatttctga
    19201 ttttttatct atcagaataa cttcataatt tgaatcacat aagtttagaa atcgagctgc
    19261 agctagcccc gaatggtttg atccaataat tactattttt ttcacttaat cacattcttt
    19321 tcccttctat gaaaagtatc ttcattttta actaacaacc tatctcccaa aataaaaaac
    19381 aaaaagagga agaaaaagat tcttcctctt ttcagagaag atttaagaaa ttgattttct
    19441 attcattctc tttttttcga tttttatacc ctaataaccc taaagttcct aacaggatta
    19501 aaccaccact aatagtaaag atattactat caatctctcc cgtcttagga taagcttttg
    19561 aggactgctt ttgaggactg cttttgcctc tatttttgtt ttgcttgcta ccttgattgt
    19621 cagtcttatt atctttacta acggcttttt cactgtcttt ttcgtttgaa gaaacaacta
    19681 cattagtagg ttcactagta ttaccagatt catcagttgc agttactatc acttttgttc
    19741 ctgcctctaa tttaggaact ttaactgtaa aattaccatt tttatcagct gtcccatggt
    19801 attgactccc gtttggtaat gtaactgtca cctctgcatt tggttcagtt ttaccagtaa
    19861 caatttggtc accctctgta ataggatcaa cttgaggttt attcggtgct tttttatctt
    19921 ctacagaaat agtaacctct acttcttctt tagatccatc tggatatgtt actactacaa
    19981 tccctttttt gtttccagct gtactaacat ctactttctc tttccaagta taagtagttc
    20041 cttttggtag atcttctttg ttcttaattc cctcagatgc gtctggctct ttatttaagt
    20101 ctgtagtcac tttttgtcct tcaggatt
//
LOCUS       DACCVZ010000052        19509 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.052, whole genome shotgun sequence.
ACCESSION   DACCVZ010000052 DACCVZ010000000
VERSION     DACCVZ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.052"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="IVW63_001844"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="IVW63_001844"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAP7860115.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="IVW63_001845"
     CDS             complement(1173..1868)
                     /locus_tag="IVW63_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAP7860116.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="IVW63_001846"
     CDS             complement(1881..2597)
                     /locus_tag="IVW63_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HAP7860117.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="IVW63_001847"
     CDS             2927..3532
                     /locus_tag="IVW63_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HAP7860118.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="IVW63_001848"
     CDS             3857..4180
                     /locus_tag="IVW63_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAP7860119.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4362..5732
                     /locus_tag="IVW63_001849"
     CDS             4362..5732
                     /locus_tag="IVW63_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAP7860120.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5862..7163)
                     /locus_tag="IVW63_001850"
     CDS             complement(5862..7163)
                     /locus_tag="IVW63_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAP7860121.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7393..9384)
                     /locus_tag="IVW63_001851"
     CDS             complement(7393..9384)
                     /locus_tag="IVW63_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HAP7860122.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9528..9794)
                     /locus_tag="IVW63_001852"
     CDS             complement(9528..9794)
                     /locus_tag="IVW63_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP7860123.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="IVW63_001853"
     CDS             complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="IVW63_001853"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAP7860124.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="IVW63_001854"
     CDS             complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="IVW63_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAP7860125.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13138..13701
                     /locus_tag="IVW63_001855"
     CDS             13138..13701
                     /locus_tag="IVW63_001855"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAP7860126.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13954..14475)
                     /locus_tag="IVW63_001856"
     CDS             complement(13954..14475)
                     /locus_tag="IVW63_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAP7860127.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14478..15320)
                     /locus_tag="IVW63_001857"
     CDS             complement(14478..15320)
                     /locus_tag="IVW63_001857"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HAP7860128.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15313..16038)
                     /locus_tag="IVW63_001858"
     CDS             complement(15313..16038)
                     /locus_tag="IVW63_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAP7860129.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16214..16510
                     /locus_tag="IVW63_001859"
     CDS             16214..16510
                     /locus_tag="IVW63_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860130.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17078..18670
                     /locus_tag="IVW63_001860"
     CDS             17078..18670
                     /locus_tag="IVW63_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750719.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP7860131.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18683..19423
                     /locus_tag="IVW63_001861"
     CDS             18683..19423
                     /locus_tag="IVW63_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP7860132.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5582 a         4002 c         3702 g         6223 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata gtaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttgattcttt gactcaattc ttggcttctt
     4261 tttatggagt ttcataaatt atcattgatt tctaattggt attctcagga taaacgctat
     4321 atactactaa ctaaatttta aagatataag gagtttaaaa gatgcgcgat ttaacaaaag
     4381 gaagccccgc taaactgatt ttgatgttca ctgttccttt actgatcgga aatgtttttc
     4441 agcagttcta caatatgatc gatatgatca tcgtgggtca gacgctaggt aaaaatgcgc
     4501 tggcagcggt tggtgcaact ggaagcctga catttttgat cattggcttt gcccaaggtt
     4561 taacagctgg tttagccatt attaccgcac aacgttacgg tgcaaaagat tatcggggtc
     4621 tgaagaaaag ttttgctgct agtgttgtca ttagtcttgt cgtcactgtg attttaactg
     4681 tcctaagtct cctgtttatt cgtccgatgc ttcaattgat gcaaactcct cctgaaatac
     4741 ttgatcaagc acaaacattt atttcaatta ttttattagg gatctttgca tcagtcagtt
     4801 tcaatttgct ttctaatgtc attcgcgcac ttggtgacag ccgcacacca ctattctttc
     4861 tgatcattgc ggtcatcatc aacgtcgtac ttgatttgat ctttattatc tattttggca
     4921 tgggtgtgga aggtgcagct attgctacag taatcgcaca agtttcttcc agcgtactgt
     4981 gtctagtgta tatcaagaaa aaaatgcctt tgttacagtt acgcaaaaaa gatttcaaat
     5041 ttgaaaaaga agagtttgct gtacacctaa atgctgcttt gccaatggcg tttcaatctt
     5101 cgatcatcgc tgttggtgct atcgtgttac aagcagcact aaatagtcta gggacagatg
     5161 tcgtagctgc tcaagccgct gctggtcgta tcgaccaatt tgcaaatcag ccgatgatgt
     5221 catttggtat tgcaatggca actttcactg cacaaaacta tggtgcgaaa gaatatggcc
     5281 gaatcttgca aggggtacgt caaactttac tgatgagtgt cggatttagt ctcttagcag
     5341 gtgctatcgt cattttcttc ggtcatttct ttgttcaatt gtttgttagc ccatcagaaa
     5401 cacgtgtatt tgaattagca caaacctact tcaatatcaa tgggtctctt tactggatct
     5461 tagcagtcct gttcatttta cgctacacac ttcaagggct tggacaaagc aagatcccta
     5521 cgatcgccgg tatgatggaa ttgcttatgc gttcttttgc agctatcgtt cttacaggaa
     5581 tgtggggata cccaggagca gcagcagctt ctcctttagc ttggatcggt tctgttgccg
     5641 tgttgcttta ctcttatatg cgttcgatga aacaattgaa acacatgggt gaagaggaac
     5701 atttcacatt agaacatgca gaagcaagat agccttgatt aaaagaaatc gttgcggcta
     5761 aaaatgaaaa cttttattga aaatatcttc ttcgtttacc gaaaacaggt tttttagata
     5821 acaaaaaggc tgtgacaaaa aatgtcacag ccttttttct tttattctat ttttctttcc
     5881 gtggactcta ctttgaaata atcgatatgt gcatgctggt attctaatac cgtgaaacgg
     5941 aatgatgcaa tctcaatgat tgttcctgct tttatttctt tatatcggct agaagcaaag
     6001 cccgcaagtg tagtaaaatt cgtttcttca aactctggaa tctctacatg aaaataacgc
     6061 tggaaatcat ctaatgttag tttgccggag atgatataag agccatctga ctgttccgct
     6121 atcaatgctt cgtccaaatc tgtctcatct cggatttccc cgacgatttc ttctaaaata
     6181 tcttcaatcg tcactaagcc gcttgtccct ccgtattcat cttttaagat agcaatatgc
     6241 tttccctttt ttcgcatgat cgtcaataat ttttttatag ggatcgtttc agttgttacg
     6301 atcggctctt caatcaactg ttctactgtc agctggtcat ctttataaga ttgcttgatc
     6361 aaatctggca aggtgacata acctaaaaca ttgtcttttg attctaagat aaccggatag
     6421 cgagtatgtc cttgttcaat cgaagctttt atcgcttctt tgacggtttc tgaagcttcg
     6481 aatacttgca tggacgtacg gtctacttgt atatcttttg ccaaggtatc atcaaattca
     6541 aacacgtttt ccaaataatg atattcttct ttggtcaact ctcctttttc ataagaattc
     6601 aatgcgacta atgtcagctc ttcttgagac aatgtctctt ctccttcaga tacgagacgc
     6661 acacctaata gcttccctag ccctgcagct gaatgattca atacccaaat aaaaggaaac
     6721 attactttat aaaaataatg aagtggttta actacgaaca agacgacctt ctccgtattg
     6781 acgatactat agctcttagg aagcagttcg ccaataacca catcgatata cgtaactaaa
     6841 ataaatccca gcgccacaga gattgtactg ctaatagccg aactaaaagg tagtttaccg
     6901 atcactggtt ctagtaaagc cgcgacagat ccttcaccga cccacccgat gatcaaaccg
     6961 gttagcgtaa ttcctaattg actagctgat aaatagttat ctaaatggtg tgtaacatga
     7021 agagctagct tggcgttctt tacattttcc ttttctagtt gttccaatct tgatcgtctg
     7081 attttcacta aagcaaattc acttgctaca aaaaatgaag taattgcaat catcaaaaat
     7141 aaaataatga aattgataac catattctcc cgcctttctc tttttctatt gtaccctttt
     7201 tctacaaaaa gattgaaaat aatgcgtatt catatttagg aataaaaaag gagatgcggc
     7261 atttttcagc cacatctcct tatcacttca aaatcattgc gttacttgtt gctaaacagc
     7321 tttttcatga cctctgataa acggtgttca agtagctgac attcgacatt agttcaggtc
     7381 aaagcgctac tttcacaacc gctctttcaa ccatgttttc cgagtatttc caatgataag
     7441 cggaacagtt tcatgtttta cttcgctgta ctctagccca aaccatgttt ctggcgaggt
     7501 agcgattttt ttgattgcca gttttgcctg catgatttga cgttgccatt ttcctagagt
     7561 tgtcacattg gaaactactt catcaatcag gacaaattgg aaatcgccaa cttctcgccc
     7621 tggtgtcaga gagtatcttt gtggctgttt tggcaaacgg ccttgtttca tcaaatcatg
     7681 gatgacttgg cgaacatata cgttgatttc ctgttggacc ctgaaaccta agaacagatt
     7741 cacttggaca ataaaatcag tgtccatcat atctacttga tattctttcg tatatggctc
     7801 atccgtcact tccacatgaa caaaccaata gactcgtgct cttttaggcc gtttatctaa
     7861 aatcgaatag atgaactgtc ggccaacttt atcttcagcc atatcaggaa ccaagaagac
     7921 cacatttgtc tgatagattg gtaaagaagt atcatcacgt aattctctaa gctgcgggat
     7981 ataatctctc aaagacacat cctcggttga cgattcgcga ataatgttcc cttgttccca
     8041 aataaacatc acgactaaga tgatcaaacc aatcagaacg gctacaaaac cgcctcggaa
     8101 gaatttgaca acacttgaga taaagaaaac gacttctatc gcaccgaaga aaaaggtaac
     8161 taaatatgca agccaacgag aatgcccatt ttggataaga taaaagtaaa gcagtgctgt
     8221 tgtcatcaac atcgtcacag tgatcgatag accgtaagca gcttccatat gatgagacgt
     8281 tcggaatgtg acaaccacta gagaacaggc gatccataaa atcagattga ctgctgggat
     8341 atacatttgc ccgatactgt tcccaggata catgatcttt aaccgaggca gcagtttcaa
     8401 cttgattgct tctgaaacta gcgtaaacga acctgtaatc aatgcttgcg aagcaatgac
     8461 tgcagcgact gttgcaaaag caacgccgat cacgatccaa ctttgaggca tcatttggaa
     8521 gaatggattc aggttcttga tttgctgtgc ttcagggttt tgataaacat tcaacaacca
     8581 cgcagcctgc ccaaaataat tgataaccaa acaaattttg acgtaaggcc agctcagacg
     8641 aatatttcgt ttgccgacat gtccaagatc ggaataaagc gcctctgcac ctgtcgtagc
     8701 caggaaaata tttccaagaa tgaacaagcc taatttgtta tctgcactaa aaagcagctg
     8761 gatagcataa taaggattca gtgcacggat aactgtccag tcttgactga agttcattaa
     8821 tcccattacg cctaaaaaag taaaccaagc gaacatgatt ggtccgaatg cttttccgac
     8881 aatatctgta ccaaagcgtt ggaccatgaa taaaacaaaa ataataacta aagtgataat
     8941 gacgatcacg ttctggttat taccgaaccg gtcaaaaaac tgcggaattc ctcgcaagcc
     9001 ttcaatcgca gtcgttaccg tcacagcagg ggtcaatacc ccatctgcta gtaaggcagc
     9061 tcctccgatc attgcaggaa tgatcaaata tttcccacct tttcggacaa gtgtgtagag
     9121 tgagaaaatt ccaccttcac catggttatc tgcattcaat gcaatcacga catatttgat
     9181 tgttgtcagt agagtcaatg tccaaaaaat caatgagact gatccgataa caaaatcagg
     9241 attgattcct gacaatccgc cattatcttc aacaatcgat ttcataacgt aaagcggact
     9301 tgtcccgatg tctccgtaga cgactcccat cgctacaagc aggccagcca ttgatatctt
     9361 tttggtattg tgcgttgttg ccacgttttt ccctcatttc ttgttatatg gatatccttt
     9421 aggtaagctt gaatgataga tgatattctt atccatgaca cccgctttcc taaattgctt
     9481 ctaattatcc aagtaacaca ctgaagtgtc aacttatttg aataaaatta ttctttcttt
     9541 ggacgttctc tgatacgtct tgccacaaat gaataaagag caaggcaaaa aattgcaccc
     9601 aataatgctg gtatcaaata aaaaccgccg agttccggtc ccagtggtcc tagtaaaaat
     9661 tcgccgagcc aactacctaa aaaaccgata atgatatttc cagatacgcc tcccgggact
     9721 tcctttccta aaattgcgcc agctatcaaa cctaatatac cgccgataaa taacgaccat
     9781 aaaaaattca gcatctcctt tccctccttt atccatattt ctcactttta ttttacgctt
     9841 tattcagaag gactccaaaa atatgcgcca agaaactcca gaaaaaaaga agttgtaaca
     9901 aaagtgttca gcttatttcc gtagaagctg cttctggaac accgtgaatc agaggttgtg
     9961 aaatcagcgg tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt
    10021 gccgtttttt gagctaatat cgagggacag ctgattgaac atcgtttatt ggagaggttg
    10081 taaaaaagct gttctgcatc aagtaataag aacagccaag taaaaacagc tcctaatgtt
    10141 tttaacttgg ctggacttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa
    10201 aaaaggactg tgacacggct tttgtcacag tccccttttt tcgaataatt attgtccccc
    10261 tgtcaccttc acgatcacaa gtacattatt cctatgaatt aaattatttt tcttcatttt
    10321 tcgttgaacc atcttcgttc aacattgctt ttcttgacag atttacgcgt ccttgtttat
    10381 cgatttcagt tactttcaca aggatctcat cacctagttt aacaacatct tcgactttat
    10441 tgacacgatc gtttgctaat tgggaaatat ggacaagtcc atcttttcct ttgatcaagt
    10501 tgacgaatgc accgaatttt tcgatacgga caactttccc tagataaact tcaccaactt
    10561 tgacttcttt ggtcaaatct tcgatgatct tgatagcttt tttgatcatt tctgcatcag
    10621 ctgaagcaat acttactttt ccatcttgat cgatatcgat tttcacacca gtttcatcga
    10681 tgattccgtt gatcgtatcg ccgcctttac cgataacatc tttgatttta gcaggttcga
    10741 tctggatcat ttcgattttt ggtgcatatt ggcttaattc ttcacgtgga gcagcaatcg
    10801 ttgaagtcaa ttcttctaag atttccatac gtgcttgttt tgcttgagtt aatgcttcag
    10861 ttaggatttg ttctgtgatt ccttgaatct tgatatccat ctgtaaagca gtgataccat
    10921 cttttgtacc ggcaacttta aagtccatat cgccaagatg atcttccagc ccttggatat
    10981 cagttaggat cgtatagttt tcaccatcag aaacaagtcc catcgcaata ccggcgactg
    11041 gcgctttgat tggtacacct gcatccatca atgctaatgt gccagcacag atacttgctt
    11101 gggaagaaga accatttgat tccaatactt ctgctactaa acggatcgta taaggaaatt
    11161 cttcttctga agggattact tgtgctaacg cacgttcacc taatgcgcca tgtccgattt
    11221 cccgacgccc tggagagcct gcacgtcctg tagaaccaac agaaaattga gggaaattgt
    11281 agtggtggat gaatcgtttg ctgacttcca cccctaaacc atcaatgatt tggtgctctc
    11341 ctagaggtgc gagtgtacaa gctgataaag cttgtgtttg tcctcgtgtg aacaaacctg
    11401 atccatgtac acgtggcaat aagctgacct ctgatgacaa tggacggatt tcatccaatt
    11461 tacgcccgtc aggacggatc ttatcgatgg tgatcaattc acgtacgaca tctttttcaa
    11521 gatcttctgt gatttgttta acttctttca acaagtgatc ttcatcttca tgacctgcaa
    11581 atttctcagc ataagcttcg cggatatcga tcttcacctg ctcgatatta tcttcgcgag
    11641 caagtttttc ttcagtcatt actgctgctt tcattgtagc gtaagaagca tcaaagattt
    11701 cttttttcaa tacttcatca acttgcagta aagtcacttc cattttttct ttccctactg
    11761 cttgaacgat ttcttcttgg aaagcaacta actctttgat agcgtcaaaa ccaaacagca
    11821 atgcaccaag catgtcttct tctgaaactt ctttcgcgcc gctttcaacc atattgatgg
    11881 cttgtttcgt tccggcaaca gtcaattcga tatctgtttg ttctgcttgt tctactgttg
    11941 gattcaagac gtactcgcca tttacacgac caacttctac gcctgcgatt gggccgtcaa
    12001 atgggatatc tgagattgat agtgctaaag aagaacctag cattgctgcc atagctggcg
    12061 agcagtctgt ttctacactc atcacgatgt tcgttacttg gacttcatta cggaagcctt
    12121 ctgcaaacat cgggcgaatt ggacggtcga tcaaacgggc agtcaatgtt gcttccgtac
    12181 ttggacggcc ttctcgtttg atgaaacctc cagggatttt ccctgctgca tacatttttt
    12241 cttcataatt gatcgttaat gggaaaaagt ctgtatcttt tgcttcttta gaggccacag
    12301 ctgcacttaa gactactgta tctccataac ggactaaaac ggctccgttt gcttgttttg
    12361 ctagctgacc gacttcgatt tgtaagggac ggccgcccca tgtcgttttg aatacttgtt
    12421 tttctgacat aacttctcct tttccttctc gtgaaagcaa gacgctacta aacaaatgaa
    12481 aactgccgaa agccgtcttt tgagcagctt tcatttggtt agtaggagtc catctagctt
    12541 gatcacggaa ttttacttaa ttgatatacg agtaaaaaaa gtgagattca tgtgaatccc
    12601 actctttttg actaaaatta acgacgcaag cctaaacgtt tgatcaattc gcggtaacgt
    12661 tgaacgtcag ttttacgtaa gtaagctaac aagttacggc ggtgaccaac ttttttcatt
    12721 aggccgcggt atgaatgatg gtcttttttg tgcacgcgtg catgttcatt caagtggttg
    12781 atttcttcag ttaatacagc gatttgtact tctggagaac cagtatcccc ttcatggcga
    12841 gcgtattcgt tgatgatttc attcttgcgt tcttttgaaa ttgccatttc tttcacctct
    12901 ttcgattatt cccctgcgac tgagtaaaac gttggtgatt cgcttaacca agtggcaggt
    12961 catgtgccta gagcacacag ctatacttta cctgaaaccg ggttgaaaat caagtagtta
    13021 atcattaaga aaaggtagtt ttcaaacaat cttactacta cttttccatt tttgtggtaa
    13081 actataatgc gaaaatagac ttgaaacaca gtcttttaag aaaggggtac atattccatg
    13141 attacaatgg atgatatcat tcgtgaagga aatccgacct tacgcgaagt tgcaaaagaa
    13201 gtttctcttc cattaagcga agaagatatc tctttaggaa aagagatgct tgagttctta
    13261 aaaaacagcc aagatccaat caaagctgaa gaactacact tacgaggcgg tgttggctta
    13321 gctgctcctc aattagatat ttctaaaaga atcattgctg ttcacgtacc aagtcctgac
    13381 ccagaggcag atggaccttc tctaagtact gttatgtata atcctaaaat tttgagccat
    13441 tctgttcaag atgcttgttt aggggaaggt gaaggctgtt tatctgttga tcgagaagta
    13501 ccaggatatg ttgttcgcca tgccaaaatc actgtgtctt attatgatat gaatggtgaa
    13561 aaacacaaga ttcgtttgaa gaattatgaa tcgatcgtcg ttcaacatga aatcgaccat
    13621 atcaacggtg tgatgttcta tgaccacatc aacgatcaaa atccatttgc actaaaagaa
    13681 ggcgtattgg tgatcgagta gagaattggc aggttccttc gatactatgc tacaagaaag
    13741 ctttataaaa aaggggagtg ctcaaaagct gcacttccct tttttatgtt tctccactaa
    13801 tcgaaattta gatagacatc tagaaatcgc aattccaaaa aattctgtgt attggatacg
    13861 catcttttct tattttttct tatttcttcc atatgggtgt ttatctcaga gatgatagaa
    13921 tagtttctag gataaaaagt agcagctacg atgttatcct tcgtagagga ttcctgcttc
    13981 agctagtttt tgtttgatgt ttttcagcat atgcttttct gggtagcgga tcgtatgcag
    14041 atggatgccg cctgttaatt cggataacaa agtagcatta cttttttgat aacgtctcat
    14101 aaaggaatcg atatcttgtg gcgttttgat gtgcaaagtt cctgctaact caccgtaaag
    14161 gggatgttcc acaattacat caatgatttc accaccattt tcaacgatta gtctcagttc
    14221 ttcttctgtt tgatcttttc catgctggac agcgatttta ctgatgtgcc cagtattggt
    14281 ttcttctgtt tcgaggatat aacctcttgc tgttgccacg atacttttac ctgcagctcg
    14341 tagtaaagca atatcgccta caatgatctg acggctgact ccaaaagttt tcgcaaactt
    14401 gctagcactc actggttttt ctgtatttgc caaggtttgc atgatttgtt ttcgccgtgt
    14461 ctctccttcg atcacactta ttcctccttc attttgtttt ggtattcgcg cgagtgtttc
    14521 atcaaatcaa catacgtgtc tgttattgtt tccttatatc ccttattttt cagcagacta
    14581 acaactttat ccaatacttg ctgctctctt tttgcatcat aaactgcttg gttttcttct
    14641 tttttcactt gtcctatttt agttaccgta tccattcttt tttctaataa agcaaccaac
    14701 tctcgatcga tcatatcgat cttatgacgt aatgtttcaa gagactcttc tgttagttct
    14761 tcctctactg tcttgatgat acgagcagga tttcctgcaa tcactacatt gtcgggaaaa
    14821 gatttggtca caaccgaacc tgcgccgact actacgttgt cccctagagt gacacccggc
    14881 gtgacgataa ctcctccgcc taaccaaaca ttattaccga ttttaatggg ttttgcgtac
    14941 tccagaccgc tgttacgttt cactggatgt agtggatgcg tcgccgtgta aagctggaca
    15001 ttcggagcga acatgcagtt atcaccgatt tcaatcgtgc tgacatctaa aaatgtacaa
    15061 ttgaaatttg cataaaaatt ctccccaaca aatatattat atccgtaatc aaaattgata
    15121 actggctcca tatagatttt tttccctgta cggccaaaag tctctttcaa caattgggat
    15181 cgcagttccg ctgattctgc ttggttgatg atttggcttt gacttcttgc aaacatacgg
    15241 tcggcaacca gctcaggatc attggcaaaa taaagctcgc ctgcaatcat tttttctttt
    15301 tcggttttga attcagtcat aatctgctcc taattcttgt atttttttga aaacaaccgc
    15361 tccgtcttct tgaataaacg tataaggctc cgctaaataa acaggcgttt gattgattac
    15421 taagattttg gctgacggct ggcgaaactg taccagatca caaaacggat gaacttgaaa
    15481 actcgttcca acaatgacga tcagctctgc ttggctgacg gcataagccg cctgctccat
    15541 gactccatct tgaaaccctt caccatataa cacgatgtct gggcgtattt gtcctccgca
    15601 tgcttgatgt ttgtcgctgt gaagatattc tttccagtct accgtttgtt gacattttcg
    15661 acaatgacat tgatacagac tcccatgaaa attgacgagt tgcgggcttt tagcctttgc
    15721 gtgcaaaccg tcgatgtttt gggaaacaac ccaaacattt ttttctttcg ctagatgtgc
    15781 tatttccaaa tgaatgatat tgggttttgc ttcaggatga taaatctttt tgacaaattg
    15841 atagaattta tccggttcat tcaccattgc ttgatgactc agcaagtatt ccggctgctc
    15901 catcccgtgg tagattcctg acaaagatcg atagtctggc actccagaag gtgtggatac
    15961 ccctgcaccg gtcaaaaatg taatttgctg ataagctaat atctcttttg ctgcttcgtc
    16021 tactgttaat tgtttcatgt tttgtcacct cactttccat tatagcccat actcgaacaa
    16081 atttattgtt gaaaagtcag aaaaatggga ataaaaaagt gttatgggca tttgagcaat
    16141 ttatcacaat gttcactgac aaaagaatga aaacgtgtta caatactgct gtataaaagt
    16201 gaggtgaatc gatatgttac cattctttat ttattggggc gttattctgg cttgtatcgc
    16261 ctggttagcg ttaagcgttt atttctctgt tttttatctt gtacgcaaag aaaatggaaa
    16321 tctttgggct tttgctttat tcaacgtgat tgccgcaatt gttttagcca ttacattagc
    16381 cgtatatcga acatggggct ggggaatcac ccaatactca agtttgattt atctaatatt
    16441 agccatttat ggcgtcgttg ttcttttgca agcgatccta ggacgtgagc caaagaaagc
    16501 ggcagcttaa atgatcgaga tggaactgga cacaggaaat tttctgttct agttcttttt
    16561 ttattgtatt acatacattt ttgtgtataa ttatactatc gtttgcaatg gatagatgat
    16621 tcacattttg attgtttttt cggtaaaagt aaagatttct atatttatca gtattttttc
    16681 aaaaaccagc agttatagat tgacaaagcc tctcgagtat cgtaaacttt ttttgtataa
    16741 ataactgaat acgagatgcc tcaatcaatg aggtagaggt cgcgagaatc attaaccctg
    16801 tggagtgaag caaacatgga gaagcaggaa tagggaggat cgccgaaatg tgcacttttt
    16861 tgcttggagt gtatgttggg acgcaagtta agagcttgcg gactgtctta gcagtgatgc
    16921 taagttgcgc tatgttttgt gagaggttta tcaccttatg gaattttagc ggccttttta
    16981 tatctataaa tcggtcgctt tttatttttt cagataaagc tttaccgcat ttcatctaga
    17041 ccgctcgtgt atcatataat cagaaaggga gaaaaaaatg aaaaaaaata tggtttcagt
    17101 tgccgtacta tttgcttttg tcttctcact attcagtgtg ggatctctgg caaatgcaga
    17161 tgaaaaaaca ccgagcgatg agtttcgcgt aggtatggag gctgggtatg cacccttcaa
    17221 ctggtctcaa caaacagatg agaataatgc cttgccaatt caaggccaaa atagttacgc
    17281 cggcggttat gatgttcaaa tcgctaaaaa agtagcagat ggtttaggga aaaaattagt
    17341 catcgtccaa acgaaatggg atggtctggc tcctgccctt caatcaggca agatcgacgc
    17401 gatcatcgcc ggaatgagcc ctactgctga acgacgaaaa gaaattgatt ttaccgatcc
    17461 ttattacgaa tcacaattag tagtagtagt tcaaaaagat agcaaatatg caaaagcaaa
    17521 aagtttagca gatctttctg gagcaaagat cactgctcag ttaaatacat tccactatac
    17581 tgtgatcgat cagataccag atgtgcagaa acaacaagca atggataatt tctcagcaat
    17641 gagaacagct ttagcttctg gaatgatcga tggttatgtc agcgaacgtc cggaaggtgt
    17701 aacggcaact agtgtgaaca aagacttgga aatgcttgaa ttcagcggtg cagatggctt
    17761 ccagacaaac ccggaagatg ttcagatttc tgttggtatg cgtaaaggcg acccggatat
    17821 ccaaaaagta aaccagattc tttctggcat ctctaacgat gaacgaacca aaattatgga
    17881 ccaagcagtc aaagatcagc ctgctgcaac tgatagtgaa gaaaaacctg gcatcatttc
    17941 tgatttcact acgatttgga aacaatacgg caatatgttc ttacgaggtg ctggacttac
    18001 cttgttcatc gcattgatcg ggacagttgt cggtactaca cttggattac tgattggtgt
    18061 cttccgttcg gtacctgaat caggaaatgc actgactcgc ttcttccaaa aaatcggaaa
    18121 tgcacttctt tctatctatg tcgaagtatt ccgcggaaca ccgatgatgg tacaagcaat
    18181 ggtcatcttc tacggtctgg cactcgcttt tggcatttca ttgaaccgaa cgattgccgc
    18241 tttgtttatt gtctctctca atactggagc ttacatgaca gagatcgttc gtggggggat
    18301 ttttgcagta gatgaagggc agttcgaagc tgcgcaagcc attggtatga cccatggcca
    18361 aacgatgaga aaagttgtta ttccacaagt tttacggaat atcttgccag caacaggaaa
    18421 tgagtttgtt atcaatatca aagatacagc agttttaagt gtaatcggcg tagctgattt
    18481 gttcttccaa ggaaactctg cttccggtgc gaatttccaa ttcttccaaa catttacgat
    18541 cgtcgggatc atctacttag tcatgacctt tacgatcacc agaatcctgc gggcggtaga
    18601 aaagaaaatc gatggtcctt cagcttatac caagcttgaa gaaatcgaca attcaaattt
    18661 gcaggaataa ggaggaagaa tcatgaatga aaaaattatt gaaatcaaac atctaagaaa
    18721 aagcttcggt gaaaatgaag tattgaaaga tatcagcgta acagtcaata aaggtgaagt
    18781 tgtgacgatc atcggttctt ccggttctgg taaatctact ttcttgcgct gtatcaattt
    18841 actggaaaaa ccaacaggcg gcgagatcat ttataatgga gaaaatgtat tagctcctaa
    18901 atataattta cctaaatatc gaacgaatct aggtatggtt ttccaatcct tcaacctgtt
    18961 caacaatatg aatgtcttgg aaaactgtat gtctggtcaa acaactgtcc tgaaacgaga
    19021 taaagaaact gccaaaaaag tagcaatcga aaatctggaa aaagttggta tggatcgtta
    19081 tatcgaagcc aaaccagcac aattatctgg tggacagaaa cagcgtgtcg caattgctcg
    19141 ggcattatca atgaatccag atgtattgct attcgacgaa cctacttcgg cgttagaccc
    19201 tgaaatggtt ggcgaagtgc ttaatacgat caaagactta gcacatactg gcttgacaat
    19261 gcttatcgtg acgcatgaga tggaatttgc aaaagatgta tctgaccgtg tcatttttat
    19321 ggataaaggt gtgattgcag aagaaggtac accagaagat atctttgtcc atccgaaaga
    19381 agaacgtaca aaagaattcc tttcacgtat tttaaatgct taggatcaat agctgattgg
    19441 gacaaagagc tgcggtgttt accgcagttc ttttttatga attactcata aaaggtaaat
    19501 ttctgaaaa
//
LOCUS       DACCVZ010000053        19038 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.053, whole genome shotgun sequence.
ACCESSION   DACCVZ010000053 DACCVZ010000000
VERSION     DACCVZ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19038
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.053"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            105..1148
                     /locus_tag="IVW63_001862"
     CDS             105..1148
                     /locus_tag="IVW63_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyhydrolase"
                     /protein_id="HAP7860133.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     VPNPTPAPSTEKVLNVPVVWQGNTMLCEGASLLEGLHYKGVATNQSLTSFVNYMPKAN
                     DNNPYHGYSGEWRHNVNGTYQGMMADPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFRNGAYHVVDPVFGAKWINASTYE
                     RAFNVTGMAVAVR"
     gene            1321..1545
                     /locus_tag="IVW63_001863"
     CDS             1321..1545
                     /locus_tag="IVW63_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860134.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEYKENIPKNLQGSER
                     YEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            1548..1805
                     /locus_tag="IVW63_001864"
     CDS             1548..1805
                     /locus_tag="IVW63_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860135.1"
                     /translation="MINEDFRSENKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGLRSYTTSEKDK"
     gene            1907..2260
                     /locus_tag="IVW63_001865"
     CDS             1907..2260
                     /locus_tag="IVW63_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860136.1"
                     /translation="MISENLSYENNKHLVKENKKVEDYKNMYIEMKKSPLCIQYKNDN
                     WKQVVEFVKPHSIRRVRRGKKKSELVNSGRAVIRVITKDYPVEYGDYILRLSYHAFVV
                     LKEEHFNEFFNLKSK"
     gene            2313..3107
                     /locus_tag="IVW63_001866"
     CDS             2313..3107
                     /locus_tag="IVW63_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860137.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSKRLRITVEYGTNESATELKQRYLDTRREASKKYNDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            3136..4254
                     /locus_tag="IVW63_001867"
     CDS             3136..4254
                     /locus_tag="IVW63_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860138.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLRTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGNSKDEVKGVVIDDDFEFDFD"
     gene            4287..4607
                     /locus_tag="IVW63_001868"
     CDS             4287..4607
                     /locus_tag="IVW63_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860139.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            4862..5754
                     /locus_tag="IVW63_001869"
                     /pseudo
     CDS             4862..5754
                     /locus_tag="IVW63_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5774..7402
                     /locus_tag="IVW63_001870"
     CDS             5774..7402
                     /locus_tag="IVW63_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860140.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMNLTIKRIYDLLSLI"
     gene            7453..7824
                     /locus_tag="IVW63_001871"
     CDS             7453..7824
                     /locus_tag="IVW63_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860141.1"
                     /translation="MRELTLSSKELEKKTALLNEIFSADCIIQSLKESSFSKLTDQEK
                     ISYMLSLDNLGTKYDESASSDKLLIELVSSLSSFGKMKRFNVILEIFAWLIPSFIWFF
                     YIFIVESELIAKVSLGLLIPI"
     gene            7909..8109
                     /locus_tag="IVW63_001872"
     CDS             7909..8109
                     /locus_tag="IVW63_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860142.1"
                     /translation="MLKRIAWDKDNKTDIELKEYKYNYFSRCIDRKLLFKKEGLEFSF
                     DEDEFEKLVMDWRKNLLDTVQF"
     gene            8243..9469
                     /locus_tag="IVW63_001873"
     CDS             8243..9469
                     /locus_tag="IVW63_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860143.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            10319..11644
                     /locus_tag="IVW63_001874"
     CDS             10319..11644
                     /locus_tag="IVW63_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP7860144.1"
                     /translation="MFDYSREPVNDYFLIDMKSFYASVECIERNLDPMTTPLIVMSRS
                     DNTGSGLTLASSPTAKKKYHITNVSRATDLPYPLPKELHIVPPRMNLYIKKNMEVNQI
                     FRKYVADEDLLIYSIDESILKVTKSLNLFTSSGTRSERRRELAKIIKDEIQKETGLIA
                     TVGIGDNPLLAKLALDNEAKSSKEFIAEWTYETVPEKIWKINEMTDFWGIGSRMKKRL
                     NHMGIMSIEDLANWNPYTIKSQLGVIGLQLYFHTNGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPKDYTRREEVELVVKEMAEQVAIRIRQHNCKTGCVRLAIGTSILEEKSGFSHQMKI
                     PITDNTKELQNYCLFLFNKFYEGQEVRHIGVTYSRLVYTDSLQLDLFSDPRKKIAEEN
                     LDRIIDKIRQKYGFTAIIHASSMLEGARSITRSTLIGGHAGGLGGLHND"
     gene            11637..11984
                     /locus_tag="IVW63_001875"
     CDS             11637..11984
                     /locus_tag="IVW63_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860145.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
     gene            12335..13156
                     /locus_tag="IVW63_001876"
     CDS             12335..13156
                     /locus_tag="IVW63_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAP7860146.1"
                     /translation="MGLLVPRANTYTIPLTKRQLIAKRYQRITRAINREFWNSESDTA
                     HSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQVIKNAFQEILPN
                     SDIRADGQVVKINFHDGIKFEIVPAFNEKDYLGESKGFIYPDSNMGGNWKATNPKKEQ
                     EAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEAMGNWKFVENNSG
                     GQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICLEKVLKKIAL"
     gene            13176..13736
                     /locus_tag="IVW63_001877"
     CDS             13176..13736
                     /locus_tag="IVW63_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HAP7860147.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNETHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            14786..15553
                     /locus_tag="IVW63_001878"
     CDS             14786..15553
                     /locus_tag="IVW63_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAP7860148.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            15579..16124
                     /locus_tag="IVW63_001879"
     CDS             15579..16124
                     /locus_tag="IVW63_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860149.1"
                     /translation="MGERTQALITVKYGNSKTKVSVSIHYQWGYGRFMLMDVLNQGIY
                     LINKAYDLRDESREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            16125..16691
                     /locus_tag="IVW63_001880"
     CDS             16125..16691
                     /locus_tag="IVW63_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860150.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTIEGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMETENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGTDDCVAYYTTAE"
     gene            16706..16954
                     /locus_tag="IVW63_001881"
     CDS             16706..16954
                     /locus_tag="IVW63_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860151.1"
                     /translation="MEGMDFIDHEDLIDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDNTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            16973..17212
                     /locus_tag="IVW63_001882"
     CDS             16973..17212
                     /locus_tag="IVW63_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860152.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEELLRKAKQKGYPDKMLKQIGYYM
                     PEERIEKESCKVLFDSEQLLVLLTQNKLICQFENN"
     gene            17229..17813
                     /locus_tag="IVW63_001883"
     CDS             17229..17813
                     /locus_tag="IVW63_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860153.1"
                     /translation="MNENKMVLSEYARLRTINWLNGMQSSGAFDGFDEENMDFESLSN
                     EDIRYYFIEWYFTEPDEEVEDEPELILERQRILFSEQDSKRLYGLYDLQLKGLKAQYV
                     ADSYDDMVEQGADRVVTYSEDDEEEWENYSDDEICFNDGYMPIEITEEEYDKVSDSDE
                     IGMCTVVSGLDIDVQRVEVAYQKMKERIKSKVES"
     gene            17920..18201
                     /locus_tag="IVW63_001884"
     CDS             17920..18201
                     /locus_tag="IVW63_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAP7860154.1"
                     /translation="MKVKNPKEKSRIQVGIDKDLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTMDMPVDVLDTDEKLEEWFNEA"
     gene            18191..18532
                     /locus_tag="IVW63_001885"
     CDS             18191..18532
                     /locus_tag="IVW63_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP7860155.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     NKSDQIKRVYFPIAEWEKVGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSAIDTKKL
                     NRFIERLQRKV"
BASE COUNT         7294 a         2421 c         3847 g         5476 t
ORIGIN      
        1 acaacaacga ttatgatctt aaaacaatcg tttatgtaat tggcaatctt acgaataatt
       61 ttcatgcaat aatgacaata aaaaatgaaa aggggtaaaa tcaaatgaaa aaatttttag
      121 taggaattct attcacaatg gggctagtat tattatcacc ttcagtttca gcagaaagct
      181 ctatttccat gtatcgtatg tataatccca atagcggaga gcatctatac actagaagcg
      241 ttggagaaag agacaatctg aaacgttatg gatggcatta cgaaggtgtc gcatggcaag
      301 ctccaacaag tggtactcct gtttatcgtt tgtataatcg gtataacggt gaacattttt
      361 acacagttga tgccggagaa agagataaga tttcacacac aggatggacg tacgaaggtg
      421 ttgcgttcta ttcctacaac ggagcaaata gagttcctgt aacacgttta tataacaaat
      481 acgtgaattg gcatcactac acgttagatc aaaatgaaaa gaacgtaatt agtaaacaag
      541 gttggaagat tgaaggtaca ggctggtatg caatgccaaa cagcgtacca aatcctacac
      601 ctgctccaag cactgaaaaa gtgttgaacg ttcctgttgt atggcaagga aatacaatgt
      661 tatgcgaagg agcttcttta ttagaaggtt tacactacaa aggtgtagcc acaaatcaaa
      721 gcttaaccag ttttgtaaac tatatgccaa aagctaatga caataatcct tatcatggtt
      781 actcaggaga gtggcgtcat aacgttaatg gaacgtatca aggcatgatg gctgacccag
      841 tagttaaatg ggcaaaaaac gttggcggta atgccgtcaa tatcactggt tcaggaacga
      901 atggaatcaa gaatgaaatt cgcaatggta atccggttgt aacttggatt acttataact
      961 atgctacgcc agagttcaaa caaatgcctt ggggtcgtgc agtatggaat ggacatgtag
     1021 ttctcgtgga tggcttcaga aatggtgcat accatgttgt tgaccctgta tttggcgcaa
     1081 aatggatcaa tgcaagcacg tatgagagag catttaatgt gactggaatg gcggttgctg
     1141 tacgttaatt gatagaatta tcaactaaat gaaataagag cttaattact gaaatggtaa
     1201 ataggctctt atttttttag aggaaatttt tgtaatacga atctataaca aaaaatattg
     1261 aatgtagtac acaaaagtgg tatattaaaa tcgtagagat tatgcgaaga ggtgattttg
     1321 atgaaccaaa gaagaagaaa aaggttagaa gaaataagcg agcgactttc cgagctaaag
     1381 gatgagttag aagtaattca agaagaagag tacaaagaaa atatacctaa aaatctacag
     1441 ggatcagaaa gatatgaaaa agcagaagaa tccgttgatc aacttgaaga agctgttgat
     1501 ggtttatccg acatattaga attgattgaa gatatagcta gctagagatg attaatgaag
     1561 atttcaggag tgagaataaa atgattgata tttcactgat agagaagtta cttttctcaa
     1621 ataagtacac cgcaaaagag ctggctacaa gatggcaaat atccgaatca gctattaaag
     1681 cctatcgtca aaataaggga agcgtaggat ggcgtgattg gaaagggatc agcattggaa
     1741 aagcagaaga cataatgaaa cgtgaaggac ttcgatccta taccacttct gaaaaagaca
     1801 aataacttaa tgtttgaaaa gataaaatat ctgtcttaaa gctatgtcaa attcaaatgg
     1861 tgaatgtttg ctaaatataa tgcaaaaaaa ggaagggaaa tattaaatga taagcgaaaa
     1921 tttgtcttat gagaataata aacatctagt taaagaaaat aagaaagtag aagattataa
     1981 gaacatgtat atagaaatga aaaaatcacc actgtgtatt caatataaaa atgataattg
     2041 gaagcaagta gtcgaatttg taaaacctca tagtatacga agagtacgaa gggggaagaa
     2101 aaaaagtgaa cttgtaaata gcggaagagc ggtaattaga gttataacca aagattatcc
     2161 agttgaatat ggagattata ttttaaggtt aagttatcat gcttttgttg tgttgaaaga
     2221 agagcatttc aacgagtttt tcaatttaaa aagtaagtaa tcatattttt ttgtagacgt
     2281 gtataaagtt aactaaattg cgaggtgatg acatggtagc aaaaaagaat actctaaaag
     2341 aagcttctga aaaatatcaa gatatgaaaa gacgaggatt aataccgaaa gacaaaaaag
     2401 gtatatggag agaatttgtt aaggaagtca gtagtgatcg aagtggcggt gactttgttg
     2461 gacgatatac agcaaaaggc tatagcaaac gattaaggat cactgttgaa tatggaacga
     2521 atgaatcagc tacagagctg aagcaaaggt acttagatac acgaagggaa gcttcaaaaa
     2581 aatataatga tttcaagagc agaggtctga ttcctaaaaa gaaaaaggga atttggcgtg
     2641 agtttttcaa ggaagaagat agcaatcgga ataagggaga cttcattgga cgatacacag
     2701 caaaaggcta cactaagaat ttagggatca aggttgaata cggaactggt gaaagttcat
     2761 gggaattgag aaatcgctat ttaaatacat tgttagagaa atataaagca gaattattgg
     2821 agttgttcga tgttaatgat tttatcgaga tggctgaaaa gtatggtcat gaagaaggtt
     2881 ttatgatcaa tgacattatg gttattgata attttacgga tttattagca cttgcgaaaa
     2941 aagcaaggga tttaagagaa acgcagatgt atctattcag aaataaaaac ggaagaaacc
     3001 ggagaactga atcgagtgag attgaagatt actacgatgc ctttacacac gatctgggag
     3061 cctttgtaga cgagataagt ggtgtaatga acaaatatag ggtctagaat aaaaaagccg
     3121 gagatgagca gataaatggg aaacaatagc atatacacac ctgaaatgca gaataaaatt
     3181 aaaagacttg tcggattagg gtggatgaca agaggaaaat tagattcttt tagtacgatc
     3241 aaatatcttt tgatggacat ttaccgtcag aacaagcaaa caggaataca ttttttgggc
     3301 tatgataagc cggaagatgc acctttcttt gttccaagtt cagcctatag agccagtacc
     3361 tccggtagca tgtataactt ggatttgttt gaggaaggag caaagatgat cgaatatgat
     3421 ttcaacgaag cctattcgag gatcatgaga aattatcctt tgccgtcaaa cacttatttg
     3481 aaagcaaaat ataatacaga tcaagctatt ttgagagcga taaatagacc aaaagtaaga
     3541 ccgtatgaaa atttaagaac gtatatgttc tttttggtta attttgaagg aacagccaaa
     3601 gaaggaacat atgctaatcc aaaatcacag tcgatgtttg cggattatgg cgaaaatccc
     3661 aaaacagcta atgagcctat ttggttatcg gagattgagc taacacttat ccttgattat
     3721 tatgatatta aagagatgga agtcctagat agccacacat ttttgacgaa aaaaggatta
     3781 ctcaaagaat attttgaaag aatcgagcca ttaaaaactg atcctgatac gttgaagctt
     3841 tataaaaatc ttagaacgaa agtatttggt gctatcggac aaaaatcatt aagagaagga
     3901 gaaacaagca ccttcgataa atacagtatg tataatcgag cgtattcctc catggtagca
     3961 ggcgtattta gagatcgtat ggttagatat gaacagaaat acgttcatag cgcatatggg
     4021 ctattaaaaa ttcggactga tggattgtat ttcagatccg aagtaccaga gtttgaagag
     4081 ctgtataaac ttggagtagt taagaaaaaa gttcatacaa tatccaaaga agaagtcgaa
     4141 aaagctttag aatttaaaaa caaaggattt gaaaataagg gctcctttgg gaactctaaa
     4201 gatgaagtta agggtgttgt gatagacgat gatttcgagt ttgattttga ctaaatactc
     4261 tttggaaaag atggtaggag gtaaatatga agaagaaaat tgtggaagga aatgtaggtg
     4321 ttattattct aaaagattca actgactatg ctaaatcaat ggcactaaaa gacgaaaaag
     4381 ttgcacgcat ggataaagat ttagttgaat ttctgatgga tgatacagaa agattaaaag
     4441 gggatcagtt tttgagttta atgaaagaca aaggcttaaa cacatatggt ttatttgatt
     4501 ataagaaatt agctatagag tgggtaaaag aaggagaaat attttttatt gaagaatggg
     4561 aaggtactga gaacttagtt cttcatcagt atcttttgaa agcttaatct aagtaaaaca
     4621 gttctgacta gttatgcttg tcagaatttc aaaggatgtt ttccataacc atcatcattc
     4681 aaaaataaag gatttgaaaa taagggttcc tttgggaaat ctaaagatga agttaagggt
     4741 gttgtgatag acgatgattt caagtttgat tttgactaga tttttttgaa aggtttaaga
     4801 gtaaacaagg taagaactaa gatcatgaag attgagagta aagaagatag aggacgaatg
     4861 tatgagaaca cactatattt atttagaaga taaaattgta gatgaaattc cggcaaaaag
     4921 tcgagaacaa gctagaaaat tatttattga aaaatacaaa gagatcaatg gagatagtga
     4981 agttccaaaa gtggtcgtaa cagttagaaa aaggcaaaca aaaaagagaa gtacgtttca
     5041 tgtcagccct gatatatata atcttataga gcgacataga agtgaagata atatttctat
     5101 ctctcaatat attgctacag ttattgatga attgatttca ggaaagtatg actatgcttt
     5161 tgattttgag gatgaaaagg attacaaaag tgttgctgtc tttcaatctg attttgagaa
     5221 gctaaaaaac tatgctggca ggagaaatgt taattttgca agactactag aagagttcta
     5281 ctccgaagag ttgggagtag gaaatgaata caagagagaa acttatgcga aattgtctca
     5341 taagttatcc caagcgctta aagaagtgac agaagttaaa gcggaactag atgctaaact
     5401 tgaagaagtg aaaaaatatc aaacagagag gaagaacaac atgaagaatc aagtggaatt
     5461 tgacgaacag aaaaatttga aaaagcaaga aaacgctata acaaaattat gaatgaactt
     5521 agctatgaac acttaacagt tcatgaagaa ttgagtgagg gtacagaaaa atatacgatc
     5581 gcagatatgg ttaatgaagt ggaaactctt ttagcttctt tctttgaaaa tggtcacgta
     5641 aacgatgaat ggcgaaaaga agaacctaaa agggttaacg cttatattgc tcgattaaaa
     5701 aggtttattg ataaatataa ggagaatagt gacaaatttt ctaaagataa ataaggagag
     5761 agtgtgatta catttgccag aaatcgaagg aatattttcg ccaaaaatag gtaaaaaaca
     5821 gttagatttc agcagttttc cgagcgtaaa tagagattat aatctaggtg atgaggtaca
     5881 gatactaaat attgatttca aagaactaga cttcgctgtt gctgtttcca acaaacccaa
     5941 ggcattggaa cgagtgaaaa aaatatacca agagaatgat caaaatatca aaaatatgat
     6001 caaaaagtat agacgagata attcaaaagt tgaagacgtt ttattcaacg gtacggcaaa
     6061 acatgatttg aatgtttata tggcattagg agtggctttg tactgtaatt caattaatca
     6121 gacagatatt ttggttaata tcgtgaggaa tagctatcaa aaaatattaa aaataagtag
     6181 cgaaacaaac ccttattatg caatgaaata tcttggggat aatttattaa atgataaaaa
     6241 attgatgcac aacactgaag agctgttatc taatttggct gcgattaact ttctattcaa
     6301 aacaggttct gaagattatt ttatagataa cgtactaaaa ggtgcttacg gaacagcatt
     6361 ttatccgctt tacaatatga aacagcataa agccgaacaa aaggataaca aacttgaaat
     6421 taaaaagatg aaagaactat taggtatagg atttgtaaag cccaattcaa aagtcactat
     6481 tgcttcgtta gcaactacta acaatgatgg gaaaatagta aatgggtttg acgattcaga
     6541 tatagatata ttgtcaaaat catatttttc tttgtatgga gattttgcag atttgatggg
     6601 tattgatagt tacttagtca ataattttga gatcaagggt agcgagctga atgatattgt
     6661 gtatttcgtt ttaatctctc tatatgcaat tgatcagaat accgagtacc gacaaattga
     6721 ctatttgcta gttttttata gtttgttata tcagttcgtt ttaactcggt tgtttaaaaa
     6781 tgctaaggaa gaattgatcc tgaattctga ttatgaaata gcaaaacaaa ttgcaagtat
     6841 tagaaaagaa aacaaatctg aagtaatcaa attaagaaaa gaattaagta ttgcgagtaa
     6901 agaaaacggt cggttagaat ctttagtcaa atcggcaaaa aaagaagagg aacttttgaa
     6961 gcaagagatt aaagaattaa aaggaatcag aaaagaactt gaacagctga ggtttgaaaa
     7021 taaagtatta aagcaattgc aggagcaaga acatagacaa tcattaaatg gtaaaactga
     7081 agagccttca ctgtctgaaa tgatagctta tctaaaacat aaaaacattc ttttagtggg
     7141 aggacatgta aattttcaaa ataaattaac tgaactatta ccaaatatta aaatgtttga
     7201 tgtaagcgaa aataatggaa agatacttaa aaatttgaat acgtgtgatg cgatttttct
     7261 atatacagat tacttgaatc atggtctata ttatcgtgtt atgagtgaaa tttctaataa
     7321 agataagata ttttatttgg ataatcatgt gaatatgaac ttaacaatta aacgtattta
     7381 cgatctttta tcacttatat aaagagagaa gtgataaata ggacacaaaa tttggaaagt
     7441 aggtaagtca ctatgagaga actaacttta tcttctaagg aattagaaaa gaaaactgct
     7501 ttattaaacg aaatatttag tgctgattgt ataatccaaa gtttaaaaga aagttcattt
     7561 tcaaaactaa cagatcagga aaaaatttct tatatgctaa gtttagataa tctaggaact
     7621 aaatatgatg aatcagcaag tagcgataag cttttgattg aattagtatc aagtcttagt
     7681 agttttggaa aaatgaaaag atttaatgtg atattagaaa tttttgcttg gttaatccct
     7741 tcatttattt ggttttttta tattttcata gttgaatctg agttaatagc caaggtctct
     7801 cttggactgt taattccgat ataaataggt tcagcaattt actttaataa cttgtataca
     7861 cgtattcaaa taaaaaagca gttattacat gaaggattaa gtggtaatat gttaaaaaga
     7921 attgcatggg ataaagataa taaaacagat attgagctta aagaatataa atacaattat
     7981 ttctcgagat gtatagatag aaagttactg tttaaaaaag aaggattaga atttagtttt
     8041 gatgaagatg aatttgaaaa attagtgatg gactggcgta agaatttact ggatacggta
     8101 caattctaaa agcaattgag gtcgaaattc cgatacttga atcatgatct atattatcgt
     8161 gttatgagtg aaatttctaa taaagataag atatttcatt tggacagtca tgtgaatatg
     8221 agcttaacaa ttaaacgtat ttatgatctt ttatatgttt ataaacatta atgaggtgct
     8281 aaaattgaca acaataacta tgacaaaaaa aatagaagta tatgttgatg gatcacaaga
     8341 agaaagggat tccttttttg attttttttg gaaaaatagt agagaatatg taaaagcgtt
     8401 gaatctggta tataaacagc taatgtttga agagttgata aaagatgcaa ttaaagaaat
     8461 ggatcaaggt tatgctgaga gagaagaaag tattcaaaat cggattgaaa agttagcata
     8521 tactgatcca atagatcaaa aaaaacttga taaagcaaaa gctgaattat ctaaattgag
     8581 aaatgaaaaa aataaagaag cgagagaaat attaacgcaa gcgatagggt tgaagagtca
     8641 aacgagaaca cgagatgtag caaaaaaatt agactttgac tttggagatt ttgttgattc
     8701 cgcaaatatg aaagctagta aagattttgg caatgatttt atcggaattg tgaccggaca
     8761 aagaacgcct agaatatata aaaatagaaa caaatatgga ttactacctt ttagaggtcg
     8821 agatattaaa atccataaag atgataagtt ttatatttat ttacctaaag gctttaggtt
     8881 taaagtgaat ttaggtagca agccaagaaa agcaagagat gttgcttcag ttttacaaca
     8941 cattatggat ggcgattaca aattaaatca aagtaatctt atttttgatg gaagaaaatt
     9001 attttttaat ctaacaattt cttttgaaaa aagctataat gaaatggaat tcaagaaagg
     9061 taatgaattg atcgtaaact ttgcagattt gtgtagcggt gaatgtttaa ttaatgataa
     9121 atctgtaatg tcttttggtg atagccaata tataagaaac ttcaaaagta aaattttagc
     9181 aatgaaatca aaagaacaaa gccgaggagt cttttctaag ggcggtcatg gtcgaaaaag
     9241 aaaattagat caagatcgat gggaagcaat aaagaaaaga gaaagtaatt ttgttaaaac
     9301 ttataataat caatgttctg caaaaatcgt taaaactgct attcgcaata aagctcaaat
     9361 tattcgtatc attgaaccag ataaggctta tggcgaatgg gcttactatc aattgaaaga
     9421 acaactagta aacaaaggaa aaagatatgg gatagaagtc agaagttagt aaattaaaca
     9481 atcgttgatt tggcaacgaa atagtgaggg aaaatccact cactgaaggg taaactccgt
     9541 caagttgtgt gaccagacgg aaggacgaat gttgttgagg ttttagaacc atataaaaca
     9601 gcatgtttct caaattttta ggataaggga aattgctagc agtttgtttt agaaccatat
     9661 aaaacagcat gtttctcaaa tgagtacttt aaattaattg atggcgttcc tgctttagaa
     9721 ccatataaaa caacatggat ttaaaacaag aagtaagtca gttctccttt tactttagta
     9781 aggaaaaata aagtattctc aataaaactt aaaataagca aacctttgtt ttaatagcta
     9841 atcgaagtaa aacccaaagc catatgaacc cctgaatcag cgaaagttta tgatgatttg
     9901 gattactaat agtttaggaa ttagatggta aatctaaatt aaacaatcgt tgatttggca
     9961 acgaaatagt gagggaaaat ccactcactg aagggtaaac tccgtcaagt tatgtgacca
    10021 gacggaagga cgaatgttgt tgaggtttta gaaccatata aaacagcata gttctcaaat
    10081 tgtttaaaat gattgtcaag ttaaaaaaat ctgggatcat ataaaatagt atagttctca
    10141 aatatgatta gaaaccctat taaagagcaa tattaagcca acttacttaa atcgtttaat
    10201 taagaacaat aatctctttt agtcagactt ttagtctgac ttttttgtat ttccaaaatt
    10261 tattctttac aaaaacgaac atacgtttgt ataattgctt gtgaatgggg gaataaaaat
    10321 gtttgattac agtagagaac cggtgaatga ctatttttta atcgacatga agtctttcta
    10381 tgctagcgtg gaatgtattg aacgaaattt agacccaatg actacaccgt taattgtcat
    10441 gagtagatcg gacaacactg gttcaggtct gactctagct tcttcaccta ctgcaaagaa
    10501 aaaatatcat attactaatg ttagtagagc tactgattta ccttatccat taccaaaaga
    10561 acttcatatt gttccaccac gaatgaactt atatataaaa aaaaatatgg aagttaatca
    10621 gatttttaga aagtatgtcg cagatgaaga tttattgatt tattcgattg atgaatcaat
    10681 tttaaaagtg acaaaatcct taaatttatt tactagttca ggaacaagaa gcgagagaag
    10741 aagagaatta gctaaaataa tcaaagatga gattcagaaa gaaacaggtc taatagcaac
    10801 agtcggaata ggagataacc cattattagc taaacttgca ctggacaatg aagcgaagag
    10861 tagtaaagaa tttatagctg agtggactta tgagactgta cctgaaaaaa tatggaaaat
    10921 aaacgagatg actgactttt ggggcattgg atcacgcatg aaaaaaagat tgaatcatat
    10981 gggaattatg agtatagaag atttagcaaa ttggaatccc tacacaatta aaagtcagtt
    11041 aggtgtaatc ggactccagt tatatttcca taccaatgga attgatcgta cggatattgc
    11101 tattccacca gaaccaacca aagaaaagtc ttatgggaat tcacaagttc taccaaaaga
    11161 ttatacgagg agagaagaag tagaactagt agtcaaggag atggcagagc aagtagccat
    11221 tcgaattaga caacacaatt gcaaaactgg ttgtgtacgc ttagcaattg gtacgtcaat
    11281 tttggaagaa aaatcaggtt tctcgcacca gatgaaaata ccaattacag ataatacgaa
    11341 agaattacaa aattattgtc tttttttatt caataagttt tatgaggggc aggaagtacg
    11401 acatatagga gtaacttata gcagattagt atacacagat tccctacaat tagatttatt
    11461 tagtgatcca agaaaaaaga ttgctgaaga aaatttggat aggattattg ataagattag
    11521 acaaaaatat ggatttacag ctattataca tgcttcatct atgttagaag gtgcaagaag
    11581 tattacgaga agcactttaa taggaggaca cgcaggagga ttaggaggtt tgcataatga
    11641 ttgaatataa cgatagagga cgtttaaaat ggtcgggatt ttatttgtct gatcatactg
    11701 aaagaatcaa tgcagacaat gtacaacgtg ctaatcataa tttggcaaaa gaacaaatga
    11761 cgactgaaga gattgcgaaa atactgagaa ctgctgtcat aaaaaataga cccgtctgca
    11821 ttcaaaaaga ggaacgaaac gctgaaggtt actatccaga tgatgtagta ggaaaaatta
    11881 ttggatatga cgagcttggt gtatttgtgg aagaagaaaa agttcactat gatgaaatta
    11941 ggaatgtttc tttctcggaa ttattaaaat ggagtcagat atgaacatta ttaaaaaata
    12001 cgaattcggt tatattacgt atgaacagct aatagaggaa ttatggggat atggtcaaca
    12061 attaattaat gaagtgggga ttgattgctt ttgtttctat attgaatccg gagcaggata
    12121 ccataagaac agatactata tatttccata tccaccaaaa tagtctctta gatattttta
    12181 aattttctcc aaatactttc aattattgtg aaatatttcc ctttaattaa tcaaattttt
    12241 tataaaagta atatataaaa taaattgctt gaagtattat atttagatat cataatttat
    12301 ggaagaaaaa ttaattaaaa aggatgagat tataatgggg ttactggttc cgagagctaa
    12361 tacttatact atacctttaa cgaaacgcca attaattgct aaaagatatc aaaggattac
    12421 tagagccatc aatagagagt tttggaattc tgaaagtgat actgctcaca gtttatacgt
    12481 aggttcttat gggagaggaa cggcaattag tactagtgat atagatataa tagttgaatt
    12541 accgatggca gaatttgaca gattcaaaaa ttatttatca aatggaccgt ctaagttatt
    12601 acaagttata aaaaacgcat ttcaggaaat actaccaaat agtgatatta gagctgatgg
    12661 acaagttgtt aaaataaatt tccatgatgg aatcaaattt gaaatagttc cagcttttaa
    12721 tgaaaaagat tatttgggtg agtcaaaagg gtttatttat ccagattcaa acatgggagg
    12781 gaactggaaa gctacaaatc ccaaaaaaga gcaagaagcc atgaaattaa agaatacaaa
    12841 aagtaataat ttattatatg ctacgtgtaa acattttcga catgtacgag atacagaatt
    12901 tacgagttat catctttcag gaatagtaat tgacagtttc gtatatgagg ctatgggaaa
    12961 ttggaaattc gttgaaaata acagtggggg tcaaaacatt agttctgtat cttatgagac
    13021 agctttatta gaatactata actcacataa agttatgggc ggtttaaatt tatactctcc
    13081 tggaagcaat caatttgtta attctgatag tagtatcata tgtttagaaa aagtattaaa
    13141 aaaaatagct ttataaagtt ttatggagga acaacatggg agacgaaaaa aagcgcttgg
    13201 aagttcaatt acgtgaagca tatggacgag taacgtatac ttacaccact catttaaagc
    13261 aagccgataa tattatttct gacaataaaa ttttaaggtg tcttcaaatt ggtttgtcag
    13321 cccttactac tggaggggta cttagtacca ttattactga taatagtgag ttaacctttg
    13381 ttgctggatt atgttcaaca atttctcttg gattaaactt atactttaag aattttgatc
    13441 ttgctgaaga agctaaaaat catcaaattg ttgccgataa attatggttg atcagagaag
    13501 aatacgtaag cttactaaca gatttaaatc gtttaagtgt tgaagatatt gtgaaaaaaa
    13561 gagatcaatt aatgaacgaa actcatgaag catataaaaa tgcccctaaa acaaatagta
    13621 aaagctatga atcagctcag aaagcattaa aatctgaaga agagcaattt tttacagaag
    13681 aggaattgga taagatgtta ccagagcatc ttagaaaaaa gagttctaaa tattgaactc
    13741 tttttttatg cttaaaattc tcttgtaatt tttctattca tctatattta agaagaaata
    13801 tgatgataga aacatctcct aaagccaccg caagccgttc taagcatagc ttagcccgac
    13861 attgctagat atgctcatct caccatgaac gtttcctaaa gccaccgcaa gccgtcctag
    13921 ccattgccta gtccgacatc gctagattag tgcatctcgc cataaaagtt ttctaaagcc
    13981 accgcaagcc gtcctagcca ttgcctagtc cgacatcgct agattagtgc atctcgccat
    14041 aaaagttttc taaagccacc gcaagccgtc ctagccattg cctagtccga catcgctaga
    14101 ttagtgcatc tcgccaaaaa agttttctaa agccaccgca agccgttcta agcatagctt
    14161 agcccgacat tgctagatat gctcatctca ccatgaacgt ttcctaaaac caccgcaaac
    14221 cgtcctagcc atcgcctagt gcctagtccg attttgcttg atcggttcca tttctgttta
    14281 tttagtgggt caacaccgta atcttaaata gccatcgcct atttaagatt actaggtctg
    14341 ctttgaaggt aaaaagtctt tcattcttca agacttttag gctttcaagc tacgcctgaa
    14401 agcattgaaa ttcatcgctc tttatttggt tttgccattt ataattcctt acgcccatta
    14461 tctttttcgc ctgtcttgcc ttgtcagaag tgtttagagc ttatctcatc tttggattaa
    14521 tacaagtggc gtaaattttt ttctaaacgc aagcgttacg aaaataattt acttaaacac
    14581 ttgtattaat ccggcagata agaacgcatt ctaatcactc ccgacaaggc aagacaggcg
    14641 aaaaagataa ataaatgaac gaaaggaaga aacataaaat gcaaaaccaa atagcgatga
    14701 agaaaaaacc acctccctct aaaacaatcc aaacaaaaaa gaattttgaa aaaccaaaaa
    14761 tcaaaaacag aaagaagcgt tcaacatgag agatagaatt ttagaagtta atcaagaaat
    14821 ggtaaacaag ttaacaaata tcagtgggaa ctatgaaaag tacgatggta ctttacttga
    14881 taattatatt tttcacgata cacaaaatat cagaattggc agaagtaaac cgagagcgtt
    14941 cattctcatc aaagagaaat atttgaatga atggaatagc acctatgaaa tggttatgac
    15001 tgataacttt gaaaaggtat tggatttcag aaatgctttg ttgggttctg atatgggaaa
    15061 tagcagtctt gaatctattg aagttgaaaa caagaccgag aatgaaggtg aaggattgat
    15121 taagaatgtc ctgaaaatcg aacaaaaata tatcagtgaa gatagaagtt tttatagagt
    15181 cacaagctcg gttggtctag caaactttgc tactaactta attggaaaca atgctagtga
    15241 atctttgcta gtgatgtgtc tgaatacaaa gaatgaggtc attgcttata gcgaagtttt
    15301 caaaggtgga attaatcaat cagtagcgat accaagagag atttttcaac tagctttgct
    15361 aaacaattca gcaaaaatcg cagtatcaca taatcatccg agcggatatg aatttccaag
    15421 tgaaaatgac aaaagtttta ctacgaattt gaaaaacgca ggaaaaacaa ttggtattga
    15481 attgttagac catatcatcg taacaagtaa aaacacaagc tattactcat ttcaagaaaa
    15541 tggttcttta taaaaattag agaaaagagg aaaacaagat gggcgaaaga acacaagcgt
    15601 taattacagt caaatatggt aacagcaaaa cgaaagtaag cgtgtcaatt cattatcagt
    15661 ggggatatgg tcgattcatg ttgatggacg ttttgaatca aggaatatat ttaatcaata
    15721 aagcatatga cttacgagat gaatcaagag aagaattagc aaaaggaatc tttgatagaa
    15781 gtacaggagt tatcaatttt gttacctatg aatctggagt gagtgcttat gatgaaacag
    15841 ggtttggtgg gcgctatgaa ccttatcaag aaacgattga agatgtgatg aagttttcag
    15901 ataacaatga tggctatgct catttagaga tggtgttcga tgaaaatgga tttagtctag
    15961 atgataaaac cagattgcga ttgtttgatt ttgagggtca acagatagga ctaaacaagt
    16021 tttgtgaaag cggaaaagag tttgctacga aagattttat taagggatac agattattgc
    16081 tagaaaatta tggaataaac ctagaagaag agagcgtgaa ataagtgttt gaaaaaagaa
    16141 aagaccagtt ccctaattta gaagcgaaaa gtcaaaaagt gattgatggt gaaatgattg
    16201 aattattcca aaaaagttat ggaaccatag aaactaccgc aagttgcaaa tactactttc
    16261 aaggaaagag aaacacgttt aaaggctttg ccgattctga tgaagaattg gcaaagaaaa
    16321 tcattgattg gcttgtcagc agtgaacacg tagcaagaga agataccgtt agaacaacga
    16381 ttgagggtga agtcctaaca ggtactagat gtgtttgttg taatcatgaa tttgtagaag
    16441 atgaaggttg ctaccgaatc aatgaatatg gtgattttat ttgccagagt tgccacgaga
    16501 tagaatttcc aaccgaaaga agttggtttg aatacatgct acaagattat gagatggaaa
    16561 cagaaaatgg tgaagtagtt ttttgtacca aagaggaatt gagtaagaga agcgatgatg
    16621 aaattgaaga ttggtgtgtg tggttagtag ggacagatga ttgcgttgca tattacacaa
    16681 cagcagaata ggagtgtgaa tcagcatgga aggaatggat tttatagatc atgaagattt
    16741 gattgatttt ggttatacat ggaaaggaat ggtaggtatt agcagaagtc ttgctaatgc
    16801 cttttacgaa agaaattatg cagtctatgt cctttatgat gacaatacag aaagccttgt
    16861 tgatgaagag tataaattgg atttagagaa tgttttatat gggatagaaa aagaagattt
    16921 agcaaaatat attttttcat ggttgggtca ataaacgaaa gagggtagca acatgacaaa
    16981 attcaaaagt aaaggtatgc aatggtgttc ttattattat gttgggaatg atgaagagct
    17041 tttgagaaaa gccaaacaaa aaggttatcc agataagatg ttaaaacaga ttggctatta
    17101 catgccagaa gagagaatag aaaaagaatc ttgtaaggtt ctttttgata gtgaacagct
    17161 attagttttg ttaactcaaa ataaattgat ttgtcaattt gaaaataatt aatatggggt
    17221 gaagaaccat gaatgagaat aagatggtat taagtgaata cgcaagattg agaaccatta
    17281 attggttgaa tggtatgcaa agtagtggcg cttttgatgg atttgatgag gagaatatgg
    17341 actttgaaag tttatcgaat gaggatatta gatattattt tatcgaatgg tattttacag
    17401 aaccagatga agaggtggaa gatgaaccag aattaatttt agaacgtcaa agaattttat
    17461 tcagtgaaca agatagtaag aggttgtatg gtttatatga cttacaactg aaaggattaa
    17521 aagcgcagta tgttgctgat agttacgatg atatggtaga acagggggca gatagggttg
    17581 tcacttattc agaagatgat gaagaggaat gggaaaacta ttcagatgat gagatatgct
    17641 ttaatgatgg gtatatgcct attgaaatca ccgaagaaga atatgataaa gtgtcggata
    17701 gcgatgagat tggtatgtgt acggttgtaa gtggattgga tatagatgtc caaagagtag
    17761 aggttgcata ccagaagatg aaagaacgta taaaaagtaa agtagaatct tgatttgatt
    17821 ggattgtttg caaagtagct aattaagagt ataatataat cataaatgta gttaatggat
    17881 ataataatga gtatattata ctcaaaagag gtgaacgaaa tgaaggtaaa aaatccaaaa
    17941 gaaaaaagca gaattcaagt cggaatagac aaggatttaa aagaaaacgc agaaatgata
    18001 ttggaagagc tagggttaaa tccaacaaca gcaatcacaa tcctttataa gcaagtggtc
    18061 gctagaggtg agtttccagt agagataaag ctaagcgaag aggaaaagca aggaatcaga
    18121 ttgcaacagc taactatgga tatgccagtt gatgttctag atacagatga aaagttagaa
    18181 gagtggttca atgaagccta atgagatagt aacggtctat gttgcattta cagataaaaa
    18241 tggtggtaaa agaagaccta ttttggtggt tagtgataaa gaagatagag tagaattttt
    18301 tggaatcaca agtcaatatg agaataaatc agaccaaata aagagagtgt attttcctat
    18361 tgcagaatgg gaaaaagtag gtctaaagaa gcaatcatgg attgacgtag ggtctttaaa
    18421 ggctattccc aaaagccgag agaacatatc atttaaaaag gttggtatgc tatcagctat
    18481 tgatacgaaa aagctaaata ggtttatcga gagattacaa agaaaagtct aacaaggctt
    18541 ttcttttttt gtttatatgt atattaagat atacgtttat ataaacgtat ttatgtatat
    18601 taaaatacac gtaaatatat acgtgattat aaaaattaag aaaatattaa gtattgttaa
    18661 atagtgataa ttagtaatat acgaattata agatacattt tatatttaat gtatgtaaat
    18721 aaataaaatg actgacggat attgaatagt aataaataac aataattcag acggatacag
    18781 tgagtgaagt agcttgctac gaacgaacag gcagaatgaa acggtagttt cattagagca
    18841 agtcgcttgc gacgtagcgt taccactgat gtaactggca agttacatag agagagtttg
    18901 cttgcaaacg aacgttaccc acttgaatag aaaacaaaaa taacatatta gtgaattttg
    18961 aataggagcc acaactcaac caaccgcttg cggtgggtga gtcccacgga ggaaaagacg
    19021 aacgaacggt cgcgtagc
//
LOCUS       DACCVZ010000054        18617 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.054, whole genome shotgun sequence.
ACCESSION   DACCVZ010000054 DACCVZ010000000
VERSION     DACCVZ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.054"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            299..1960
                     /locus_tag="IVW63_001886"
     CDS             299..1960
                     /locus_tag="IVW63_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7860156.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2377)
                     /locus_tag="IVW63_001887"
     CDS             complement(2030..2377)
                     /locus_tag="IVW63_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HAP7860157.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2461..3402
                     /locus_tag="IVW63_001888"
     CDS             2461..3402
                     /locus_tag="IVW63_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7860158.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3403..4446
                     /locus_tag="IVW63_001889"
     CDS             3403..4446
                     /locus_tag="IVW63_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7860159.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4452..5522
                     /locus_tag="IVW63_001890"
     CDS             4452..5522
                     /locus_tag="IVW63_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860160.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5512..6465
                     /locus_tag="IVW63_001891"
     CDS             5512..6465
                     /locus_tag="IVW63_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7860161.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6477..7487
                     /locus_tag="IVW63_001892"
     CDS             6477..7487
                     /locus_tag="IVW63_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7860162.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7772..8593)
                     /locus_tag="IVW63_001893"
     CDS             complement(7772..8593)
                     /locus_tag="IVW63_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAP7860163.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8690..8968)
                     /locus_tag="IVW63_001894"
     CDS             complement(8690..8968)
                     /locus_tag="IVW63_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860164.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9236..11245
                     /gene="metG"
                     /locus_tag="IVW63_001895"
     CDS             9236..11245
                     /gene="metG"
                     /locus_tag="IVW63_001895"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAP7860165.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11724..12311)
                     /locus_tag="IVW63_001896"
     CDS             complement(11724..12311)
                     /locus_tag="IVW63_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860166.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12486..13808
                     /locus_tag="IVW63_001897"
     CDS             12486..13808
                     /locus_tag="IVW63_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7860167.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13963..14739
                     /locus_tag="IVW63_001898"
     CDS             13963..14739
                     /locus_tag="IVW63_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAP7860168.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14732..15301
                     /gene="rnmV"
                     /locus_tag="IVW63_001899"
     CDS             14732..15301
                     /gene="rnmV"
                     /locus_tag="IVW63_001899"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAP7860169.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15294..16178
                     /gene="rsmA"
                     /locus_tag="IVW63_001900"
     CDS             15294..16178
                     /gene="rsmA"
                     /locus_tag="IVW63_001900"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAP7860170.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16629..17258
                     /locus_tag="IVW63_001901"
     CDS             16629..17258
                     /locus_tag="IVW63_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860171.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17382..18491)
                     /gene="ugpC"
                     /locus_tag="IVW63_001902"
     CDS             complement(17382..18491)
                     /gene="ugpC"
                     /locus_tag="IVW63_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAP7860172.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
BASE COUNT         6081 a         3346 c         3786 g         5404 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgtggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt ttttcatttg attgctcctt tatttttggt
     2401 tcattatcta ataatgtagc gaaacatctg tcagaagtca aaagctaggg ggaaacatta
     2461 gtgaatagtt atatcaaata tgtattaaaa cgtgtctttt tcatgatcat cacgctttgg
     2521 ttaattgcaa caatcacctt tttcttgatg caattgctgc cgggcacgcc atatacgaat
     2581 caggaacgtt tgagtcctga aacaatcgag atgctaaata aacaagtcgg tttggataaa
     2641 ccagttatcg tacaatatgg gatttatctt tctaatttgc ttcaaggaga ttttggaatt
     2701 tccttccaat ttaaaaacca gccagtcgca catttgttag ctggaagaat cggaccatcc
     2761 ttgcagttag ggttacaggc aattatcttt ggaacagtcc tagggacgat tttaggaacg
     2821 atctctgcca tgaagcaaaa tacatgggca gatacatctt ctacactcgt agcgatatta
     2881 ggtcgttcca ttccaaactt tgtatttgct gttttattac aatatatctt tgcaatcaaa
     2941 ttacaagttt tgccaatcgc aaaatgggat ggctttgtgt acacaatctt accaacaatt
     3001 gcgttggcca tgtcgccgct tgctgactct gctcggttta tccgtacgga aatggtggaa
     3061 gtactgcata gtgattatgt ggaattagca aaagcaaaag gattgagccg ttgggaaatc
     3121 gcctttaaac atggtcttcg aaatagtttg attccattga tgactttatt aggaccgtta
     3181 gctgtagcat tgatgaccgg atcactggtg gtagaaaata tctttgctat tcctggtatc
     3241 ggggaacaat tcgttaagtc aatcacaaca aatgattatc ctacgatcat ggctgtaacg
     3301 atcctttact catttatgct gatttttgtt attttgatcg tggatctatt gtacggtcta
     3361 gttgatccaa gaattcgtgt ttcagaaggg agccgaggat aaatggaaat gataccaaag
     3421 cgttatgaaa cagttgcaga tatccctgcg gatgaatttc ttccattaca aaaaaatacc
     3481 gaagaagaac gtgaacagat tactgcacct tctttgaatt ttatccaaga ttcatggcgc
     3541 cgtttaaaga aaaacaaagc tgccgttatt tcaatggttt tactattggt catcattttg
     3601 atctctgtga tcacaatctt tgtttctcct catgatccaa ctgcccaaaa cgtggcttat
     3661 atcaatttgc ctcctcgtat tccgggaatc aatatcgatg gattgaatgg aaaagcaatg
     3721 gttggtggtg aacttgttga taaatatgct caagcaaacg tcccttcaaa cgtaaatttc
     3781 tttttaggaa cagacggttt gggacgtgat gtattaagcc gcttatttat gggaatgaga
     3841 atctcgttgc tgatcgcatt tattgctgca ttactagatg taacgattgg tgtagcttac
     3901 gggttggttt ctggtttgtt aggcggacgt gtcgataacg tgatgcaacg ttttttggaa
     3961 atcttatcag gaattccaaa cctcgttgtc atgattttga tgttggtcgt ttttgaacca
     4021 ggaatttttt caatcgtggc tgctatggcc atcacaaact ggataccaat ggcacgtatc
     4081 gttcgtgcac aaacaatgaa attaaaagat caagaatatg ttttagctgg attgacatta
     4141 ggtgaatcaa gaatgaaaat tgcattcaaa catattttgc cgaatatctc tagtgtcatt
     4201 attattcaaa tgatgtttag tattccatct gctattttct tcgaagcctt tttaagcttt
     4261 atcggtttag gtcttacgcc tccgtcagct tcattaggaa cgatgttgag cgaagggtac
     4321 aagacattcc tgtatctgcc ttatctatta tggattccgg cagtaacttt atcggttatc
     4381 atgattggct ttaacttact tgctgatgga ttgcgtgatg cctttgatcc taaaatgaaa
     4441 gagtgaagac gatgacgaaa attttagaag tgaaagactt agaaatctct tttgatacgt
     4501 atgctggaaa ggtacgagcg attcgcggtg tcaattttca tttgaataaa ggagaaacat
     4561 tggcgatcgt tggggaatct ggaagtggaa aatcagtgac gaccagaagc atcatgcgct
     4621 tgctgtcaag caacgccaat atagatgctg gtcaaatcct ctttaaaggt aacgatatcg
     4681 ttggaaaatc agaaagagag atgcaaaaaa tccgtggtaa agaaatagcg atgattttcc
     4741 aagatccaat gacctcttta gatccgacga tgcccattgg gaagcaagtc gctgagtccc
     4801 ttagaaagca taataaagtt tcaaaaaaag agggacaaaa agctgcatta gaattgctta
     4861 aattagttgg aatacccgaa gctgagaaac gtatcaacag ttatccgcat cagttctcag
     4921 gaggtcagcg tcaacggatc gtgatcgcga ttgcactggt atgttatccg gaaatcctga
     4981 ttgctgatga acctacaaca gcgcttgatg tgactattca agcacagatt ttggagctgc
     5041 tgaaagaaat tcagacaaaa atcgatacat caattatctt tatcactcat gaccttggtg
     5101 tagtagcgaa tgtcgctgat cgtgtcgctg tcatgtatgg aggaagaatc gttgaagttg
     5161 gaacatcgga agaaattttc tacaacccgc aacatcccta tacttgggga ctgcttggtt
     5221 caatgccgac attagatagt gcgaacgatc gattgtatgc tattcctggt tctccaccgg
     5281 atttattgaa cccgccaaaa ggagacgcat tctatccaag aaatgaattc gcgatgaaaa
     5341 tcgatgcaga acaagaacca ccattttttg aactatcaaa aacacacaag gcagcaactt
     5401 ggctacttgc tccgcaggca cccaaagtga caccgccaga agaaatccaa cgtcgctggg
     5461 ctatctttaa agagaaacaa aaacatactt acggtcaagg aggaattgct gatgccaaat
     5521 aaactacttg aagttaaagg attgaaacag tatttcaatg taggaaaaaa gaatgaagta
     5581 catgctgtaa atgacatcag ctttcacatt tatgaaggag aaacattcgg tttagttgga
     5641 gaatctggaa gcggaaaatc cactactggc cgtacgatca ttcgcttgaa tgaacctact
     5701 gatggtgaga tattattcga cggtcaagat ataacgaaga tcaaagataa aaaaggtttg
     5761 acgaaattcc ggcatgatgt tcagatgatc tttcaagatc catacgcttc gttgaatcct
     5821 cgtatgaaag tcagagatat cattgccgaa ggaattgatg ttaatggact agctaaatca
     5881 tctgaagagc gtgcaaaaaa agtcgatgat ctattgagaa ctgttggatt gaatccaagc
     5941 cacggtactc gttatcctca tgaattttca ggtgggcaac gccagcgtat tggtattgca
     6001 cgagcattgg cagtaaaacc gcgttttatc atttgtgatg aaccaatttc tgcactagat
     6061 gtgtcgatcc aagcccaagt ggtcaatttg ttgcaagatc tccaaaaaga acatcaattg
     6121 acctatctat ttattgcaca tgatttgtcg atggttaaac atattagtga ccgaatcggt
     6181 gtaatgcata acggcttgtt attagagatg ggaacaagtg atgaaatcta taatcacggt
     6241 gttcatcctt atacagaaag tttgttatct gctattcctc taccagatcc agaccatgag
     6301 agaaaacgca gaagaatcaa atatcaacct gaaccagatg acggacaagt acgtcaactt
     6361 cgtgaaatcg caccagaaca ttttgtctat gcaactgagc aggaagtccc atattacgca
     6421 aaaaaactaa aacgacaaaa ggaatctctt ctggttgcta actaggaggg acatagatgc
     6481 taaaagcttt taaattccgt atgtatccga cagaagaaca aaaacagcaa ttgattcgta
     6541 cttttggatg tgctcgattt acctataacc atttgctgaa aaagcggcag aaaagttggc
     6601 aacaaacagg agtagccaat ttttcgctca cacccgctac attaaaaaaa gaatacccat
     6661 tcttaaaaga agtagacagt cttgctttag caaatgcaca gcttaatttg gatcgggctt
     6721 ttcgcaatta tttcaaggga cgtgccagct tcccaaagct taaaacgaaa aaaagtatgt
     6781 ggcaatctta tacgaccaac aaccaaaccc gtacgatcta tctggaaaat ggctacttaa
     6841 agttaccaaa acaaaaagaa ctaatcaaga taaatcagca tcggccagtt gaaggatcga
     6901 ttcgctccgc tacgatttct gctcgatata atgaagaatt ttatgtcgca ctactttgtg
     6961 atgtttcgcc agtaaaaaaa gaatctttag ctaaatggat cgggatcgcc tatcatccga
     7021 agacattgat ccaaacatct cgacctctag aagtaacttt accaaaattt caccagacag
     7081 aagaaaagct gcaacatgca cagcggaaat tgaatgtgaa agtccgctcc gctcaccata
     7141 gaaagatcag gttagatcag gcaagcaatt atcagaaaca aaagagaaaa gtaatggatc
     7201 tttatctgaa acaaaagaac cagcgagaag attatcttga acaattatct gggaaattgg
     7261 tcaaacaata tgactactta tttgtagaat cttttccaaa agaagaggca catgctgatt
     7321 tttctattca cgactggcat aaattaataa caaaattgcg ttataagtcc caatggtata
     7381 ataaaaaatt tcttttgatc aataccgacg gagcagaaga aagcaattcc gtaagaaaga
     7441 gccaagtagt agaaaaaatg ggcagacatt cggttatcaa gggataaaaa atgaatgaaa
     7501 ctgataggag cgttagggtt agccttgtta ataaaaagtc ttaatgactt ttgtttctag
     7561 gaatttttct tttgaagaaa agctcactaa ttatgacaaa ccaataaaac aatagcagaa
     7621 aaagttcgta cgagcttttt ctgctattgt taatttttta ttcagaaagt ttacgaatac
     7681 atcaaaattc tgaaacaaaa aacgtaactc acaaagagtt gtttttgcgt tttttcttga
     7741 atgattaggt ctgaatcttt tgctcacaac cttattcatg gtgccccggc ttgagctgat
     7801 agatttttga aggacggccg attcctacag gacgttcacc gatctcatcg aaatattgga
     7861 gcatagcttt cttaaaattg gaatgatcga tcgttttata atcgatccct aagaatttag
     7921 caaatacttt tcgagcttcc gtaatcgtga aatctttacc taaaacttgt agaacttgcg
     7981 gctcgtgttc cattttattg actacacggt tgaatgcttt caagatgatt tgactatggt
     8041 caaaagccaa agtatctttg ccagaagact ctccagtgac taaatcaagc gagatagcca
     8101 cttctccgct agataaatgg atcttgttac tatgacgttc tagtgtgaac cagcgtactt
     8161 ccttggcatc atctccggcg attagcggtt cttctccaat aaaggctaag tagctgactg
     8221 tgacgaccca gcctcgcgga tctcgattag gcgtactgaa tgtatgcagt tgctcaatat
     8281 tttcttttga aataaccaca ccagtttctt cctttgtttc tcttaagacg ctttctccag
     8341 ttgactcatc cttttggaca aagccaccag gcaatgccca tgaatttcga taaggatgcc
     8401 cttttctttg gatcaacaaa actttcagct gatcttcttc tttgttatag cacatcagta
     8461 cgatatcgac agtcaaagag ggcttgtcat attctggacg ttcctgtttt tgataccagt
     8521 taagaaattc ttcttcactt gctttatgtt cataatataa tttttcttct tctttagaag
     8581 caaaacggtt catctgacca cctccattga cagtaaaagt actttttacc ttattgtagc
     8641 agactctgaa aaaaaaccaa ggatttactt gaaaaatcta ggttatcatt taaatatgaa
     8701 aaataaatgg aagtatgaga ttgaataaaa agaaaagcag ataaaacggc aatactttat
     8761 accgctcttc acgaatggca aagaagccac aaataacgat atatacgtca atgataaaac
     8821 gcaaaatcca agctgctgtc ataaaactgt tcaaatgccc atggaggtta aaataaccat
     8881 acatacgaat ataaaaatag ctgaatatta aatgtgctaa tgaaagaaaa gcaatactaa
     8941 gtgtaaaaaa aagatgtttc ttctgcatga ttgttccagt cccttactaa gatagatagt
     9001 ctttattata ccacgtgtga ggggagaaat aaaaagccgt tttttagtag atatgaaaca
     9061 aaacaaaaac ccgcatttat tcaacctatt catcctttta aaggatagat tgaacgtaga
     9121 tagaagtcgt ttatccagtc tttttcattt tgaaaaaaag ctaacagcat gcttttttta
     9181 tggtatacta gcaaggaaac gaattcgcat catgcgataa aggaggaaga gccccgtggc
     9241 agaaaaggaa actttttata tcactacgcc aatctattat ccaagcggca aacttcatat
     9301 cggcaactcg tatactacga ttgcatgtga cgcaattgct cgttataaac ggttgatggg
     9361 ctttgatgtg ttttatctca ctggagtgga tgaacatggt caaaaaatcg aaacaaaagc
     9421 agaagaacta ggtgtaaaac cgcaagaata tgtagataaa atggcggctg atgtcaagaa
     9481 attatggaaa acgcttgata tcagttatga taaattcatt cgcacgacag atgattacca
     9541 taaagcagct gttcaaaaaa tatttgatcg tttattagaa cagggagata tttacttagg
     9601 tgaatatgaa ggctggtact ctgtttctga cgaagaattc tttacagaaa cacaacttgc
     9661 agaagtgtac aaagatgacg aaggtaacgt gatcggtggt aaagcgccaa gtggacacga
     9721 agtagaattg gtaaaagaag aatcatactt cttccgcatg agcaaatacg cagaccgtct
     9781 attggaatac tatgaagaac atcccgaatt catccagcca gaatctcgta aaaacgaaat
     9841 gatcaacaac tttatcaaac caggattaga ggatcttgca gtttcacgaa caacttttac
     9901 ttggggagta ccagtcaaga gtgatccgaa acatgtggtg tatgtatgga tcgatgcatt
     9961 atccaattat attactgcac taggatatgg ctccgaagat gaaagtctat tcgaaaaata
    10021 ctggcctgca gatgttcaga tggtcggtaa agaaatcgtt cgctttcata cgatctattg
    10081 gccaatcatg ctgatggccc ttgatttgcc tctacctaaa aaagtatttg ggcatggctg
    10141 gctattgatg aaagacggaa aaatgtctaa atcaaaagga aatgtcgttt atcctgaaat
    10201 gcttgtggaa cgttatggtt tagatgcact ccgttattat ttgcttcgtg ctgttccgtt
    10261 tgggtcagat ggtgtcttta cgccagaaga ttttgtttcc cgtgtcaatt atgatctggc
    10321 aaatgatcta gggaacttat tgaatcgaac gattgctatg atcaacaaat attgtgatgg
    10381 actcgttcct gactatgcct cacttgtcac tccatttgat agtgaactgt ctacgacggc
    10441 tgctaacgtt gtcggacgtt accatgatgc aatggaaaaa atggaattca atacagcatt
    10501 ggctgaaatc tgggtgctga tttctcgtgc aaacaaatac attgatgaaa cagaaccatg
    10561 ggtattagca aaagacgaag aaaagaaagc tgaattgaat agtgtcatga tccatttagc
    10621 tgaatctttg cgtatcgcag cgatattact tcagccaatc atgacagaaa cgccagagaa
    10681 gatcttcaat caactaggat tggactctga aacaatgaat cttgaaggat tacactttgg
    10741 cgaatttcct tcaggaacaa aagtagttgc aaaaggtaca ccaatcttcc cacgtttaga
    10801 tatggaagaa gaagttgctt ttattcaaga aaaaatgtct gaaggtactc aaacaaacga
    10861 agatacagtc aaatgggatc cagaagaaac agaacttgtt tcaacgaaag aaaaacaaat
    10921 caaatttgat gtatttgaaa aagtagaact aaaagtagca gaagtcatca actgtcaaaa
    10981 agtagaaggg gcagataagt tgctgcaatt ccgactagat gctggagaca gccaagaccg
    11041 tcaaatcttg tcaggaatcg ctgaatttta tcctgatcca agcgaattga tcgggaaaaa
    11101 agtcgtcatt gtagcaaatc tgaaaccacg aaagatgcgt ggacaaatca gtcaaggaat
    11161 gatcctttct gcagaagcac cagatggctc tttacaagta atcgaagcac caaaatccat
    11221 gccaaatggc tcagaaatcg catagaaatt caaagggggt atgacactag ttgtgtcata
    11281 cccccttttt ccgaaatttg agaagcaatt ttcgtaaatt ccttcttatt acttgaagcc
    11341 aatcatataa tacagaaaca gagaactatc caaaataaat cctagaaaaa gaagtacgag
    11401 cttcgctgat ttttgttaat ttagaataat actaatagga atcgtaaaaa cagaaaaaaa
    11461 gcataatgat aaagggtcgg gcagatttta attgattcat ctggtactct tttttattgt
    11521 ccttacattc ataaagtttg aatgcaatga ctttattaca tctatattta tatctaacag
    11581 tagcgttgat gtgttaatta taagttctat cactttatgt tcaattagtt tgtgctctta
    11641 tatgtgtgat tgaaaatata gataaaaaaa caatcatcgg ctttgacttc gatgattgtt
    11701 ttctttattt tgtaaaaatc ctatcacttg attttatggt aaccttttat ttttgtcttc
    11761 aaacggcttg gtaagagagc agtaagcagt gcaaatggga tcgaaaagac ataccagaaa
    11821 atcgtacgtc cgataccata atgttgatag agctttgtca acatcacgtg taacaagatc
    11881 aaccctaaaa gcaaggagcc agctataaac caatgattat cccaatgcat gacttcacta
    11941 agtgccatca ctccaaaagg atagaaataa aaatagatcc cgactaaggt catccgccag
    12001 ttctttgtaa atgttccgat attcaataaa aagaaaatcg ctgaaagcaa aataccgata
    12061 ggcggaaaaa gcccaaccaa aaaggaatac aacatccccc acaagatcat cacaggacct
    12121 ttgatcaatg caacgattgc gatgaacaaa gtcagcaata ttagtttttg tgataacgtt
    12181 gcaacagtca ttaatccaaa taaaattaat gtgaaccaat gccaatggga ctgctgttgt
    12241 tctttacggg aaaaatcgac ccggttggat aaataatctg ctaatttcgg ataagaacgc
    12301 ttaaaatcca taaactgttc ctccttcgtg gaaaaggtag gtttagtata cgaaaaataa
    12361 aaaagaaata catccgtctt aagagggagt ttttcactga aagtggagaa aaaagaatgg
    12421 taaattaaaa tattctcagt tatactgaaa attataccaa atttcaaaga agaaagagga
    12481 tgggaatgaa aggcaaacta aaacgagaaa tcaatctgtt tggcgcatta gctaccgtta
    12541 tgggaaccgt gatcggtgca ggcgtcttct tcaaaactgc tgctgttact gctagtactc
    12601 agtctacaag tttgacattg ctagcttggc ttttgggtgg tttcttaacg atctgtgctg
    12661 gattgacagt ggctgaatta gctacagcaa tcccggaaac tggtggagct gtaaaatata
    12721 ttgaagctgc gtatggaaaa ttgcccagct ttttattagg atgggcgcaa agcttgattt
    12781 actttcctgc taatattgct gcattatcga ttatctttgc gacacaattg acgaacttat
    12841 tacaattatc taccgattat cttttgttga ttgcagtgat caccgctgtt tctgtgacag
    12901 ggttgaattt gttagggaca aaagtcggtg cttctgtaca atcagtgacg ttgattgtta
    12961 aattaatacc aattgctgtg attgtcatat ggggattatt gaccccagga caaggaactg
    13021 tccagttatt tccaatcgaa gctggaaaag atgttacttt tgtcgaagga ttgagcagtg
    13081 cgttgttagc aacgttgttt gcttatgacg gctggttagg tgtcggtgca atggcagggg
    13141 aaatgaaacg gccggaaaaa gatttgccta aagcaattat tcttggtttg agttttgtaa
    13201 cagtcgttta tctattgatc aattttgttt ttttgaaaac tttgccgatt gatcatcttg
    13261 ccggtaattt gaatgcagct tctgaagcat cagacgtcat ttttggagga atcggtggaa
    13321 agctggtcac tattgggatc ttgatctcgg tatacggtgc attgaacggt tatacactaa
    13381 ctgggatccg cgtgccttat gcgatggctt tagaagacga gctacctttc agtaaacagc
    13441 tgacaaagct ttcaaagaag tttacggttc cttatgttcc tgcggttttc cagttagcag
    13501 tagcttgtat tatgatgagc cttggttctt tcgacttttt aacagacatg ttgatttttg
    13561 tgatgtggct attcagttta ctgattttta tcggtgtctt tattttaaga aaaaaagcgc
    13621 cggaattgcc acgtccatat aaagtaccac tttatccaat cgttccgatt attgcgattc
    13681 tcggtgctat tttcatttta ggtatgacga tgatgacgca aacgaaatta gcattgatcg
    13741 gtataggtgt taccttgata ggtatcccag tctattatca aaaaaagaaa aaacgctcag
    13801 aagagtaaaa tatttcaaca acagacagaa aaagtacgaa ctaggtcctc tagatcttcg
    13861 tgctttttct atttcaataa aacaagttct tctattttga tttttgctac ttctgcaagt
    13921 agtgcttatg tgctaaagta agaatgaaaa ggagagataa acatgatatt tgattctcat
    13981 acccatttaa atgctgaaca gttcaatgaa gatattccag aaacgattca gcgagcacaa
    14041 gaaatggggg taacgaaaat ggcggtcgtg ggcttcgata cgccaacgat tgaaaagtct
    14101 ttgcaattaa gccatgacta tccaaatata tacagtatta tcggctggca tccgacagag
    14161 gctggcagtt atacgaaaga aatcgaaaat aaattacaag aacaattgac tttaccaaag
    14221 gttgtagcat taggggaaat tggcttggat tatcattgga tggaagaccc gaaagaagtc
    14281 caagataaag tatttcgcag acagattgct atcgcaaaag aaatgaacct accaatcagt
    14341 attcatacta gagaagcact tgaagacacg tatcaaatcc taaaagaaga agatgttcga
    14401 gatatcggtg gaatcatgca tagtttcagt ggtgattatg aatgggcaaa acgatttctt
    14461 gacttaggga tgcatatttc atttagcggt gtcgtcactt tcaaaaaagc attagacgtc
    14521 caagaggctg cagcaaatgt accaatcgaa cgattacttg tggaaacaga tgccccttat
    14581 ctggcaccag ttccttttag aggaaagcga aatgaaccag gctatactcg ttatacagta
    14641 gaaaagattg ctgaacttcg gaatcttccg acagaagaag tggctgccca aacatggaca
    14701 aatgcgcacc gattatttgg tctaagcgaa catggataag atgaagatcc aagagattat
    14761 agtcgttgaa ggaaaagacg atacaagaag gctgcgggaa gtagttgatg cagatacgat
    14821 agaaacaata gggtctgcaa tcaatgaaga gatcctgatg caaattgaac atgcccaaga
    14881 gactcgtgga gtgatcgttt ttaccgatcc tgatttttca ggagaaaaaa taagaaaaat
    14941 cattatggaa gctgttcctc aggcaaaaca tgcttttttg ccgcgcacac aagctaaacc
    15001 aaagaaaaag ggaagccttg gtgtcgagca tgcaagtgat gctgctattt tagaagcatt
    15061 gaaaaaggtc gtgacgccag acatttccca aacggctgtt tctgaaatca ctagacaaga
    15121 ccttttagac tatggtttaa tagctggggc acaagcaaaa gaaaaacgag aaaaactagg
    15181 tgacgagttg cgcatcggtt acacgaacgg caaacaattg gaaaaacgtt tgaagatgtt
    15241 tcgtattacg ccgaaagaac tcgcccaagc aatgaaaata gtggaggaac aacatgagtg
    15301 aatatcgtga aattgcgaca ccctctagaa caaaagagat tttattgaaa catggttttt
    15361 catttaaaaa aagtttagga caaaattttc tgactgaacc aaatatttta aggaaaatcg
    15421 tagaaactgc gcaaatagat gaacatacga acgtgatcga agttggacca ggaatcggtg
    15481 cattgacgga acaattagcc aagcatgcaa aacaagtcgt agcatttgag atcgatgatc
    15541 gtttgatccc tgtattggct gatacgatgc aaccctatga caatgtgact attgtacatc
    15601 aagatatttt aaagaccgat ttgtcaacag ctgttagaga aacatttcat gaggagcttc
    15661 cgttaaaagt cgtagcgaat ttaccttact atattacgac accgatcatg atgcattttc
    15721 ttgaatcaga tttggttgtg gatgaactag tcgtcatgat gcaaaaagaa gtagctgatc
    15781 gtatctctgc tgaaccagga acgaaagctt atggttcatt atcgattgct gttcaatatt
    15841 atatggaagc cagtttagca ttcatcgtac caaaaacagt atttgtccct cagccaaatg
    15901 tagattcagc gattttgaaa ctgacaagaa gagatatacc ggcagtcgaa gtgacagacg
    15961 aaaaagcatt tttccgattg acaaaagcgg catttcagca aagaagaaaa acgctttgga
    16021 ataacttgca gcattcgtat ggcaaagatg accagacaaa agcatggtta gcaaaaagct
    16081 tggaaacagc tggaatcgat ccaaaacgtc gtggggagac tttgtcatta caagaattcg
    16141 ccgcattaag caatgcgatg tcagaaaata tgcagtaaaa aaagaggttg tgacagaagt
    16201 tgtgaaaaag ctgtcctgca tcaagtaata agaacagcca aacaaaaata gttcctcatg
    16261 tttttcgttt gtttgggctt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    16321 aggttgtggg cctgccgttt aactctaagt cacaaggaac aatttcaaaa aacagcttct
    16381 catgtttttg agttagttgg tcttattact tgatgcaagc ttttgaccac tattatgccg
    16441 aacaaggaga tgtgacacaa attttgtcac atctcctatt tttgtttctt gatcaaaaaa
    16501 ttcttatact tgatactcac actcattttg tatggattta gaaaagaata tgtgtcttga
    16561 cagttattag taagtgagtt atactaagtc gacatttatg tgtcaagaca tattaggaga
    16621 gagaaaaaat gagaaaaaat tcagttcgaa aactaacgat ttctgcttta ttgattggga
    16681 tgggggtcat tatcccaatg gtcatgccta aaatcatgat tccaccagct tcctttactt
    16741 tggcgtctca tgtgccatta tttattgcga tgttttttac accaggagtt gcagtggctg
    16801 ttgcgctagg tacgacattt ggtttctttt taacaacgcc ggttatcatc gcattgcgag
    16861 cattgtcaca tcttgtgttt gcgttgattg gggcttggta cttgcaaaag catccgagta
    16921 tcgttttaaa aaatggacag tttacttttg ctaattggcg tttccaaggg ttcaattttg
    16981 tgatcggtgt gattcattct ttagcagaaa tgctagtagt cagcatcttt tactttattg
    17041 gtaatatgcc tgaaacatat tattctcaag gatattttta tacagtattc atcttgatgg
    17101 ggattggtgg gcttatccac agtttagttg attataatat tgcttatttt atagcaggaa
    17161 cactcagcaa atattttgat atccccgtat ttacggcagc aaaaaaagaa aatcggaaag
    17221 agtcgattca agggtacgcg aagaaaacga catattagac atgatctctc aaaaaaaaaa
    17281 ctctcatcta gtaatggata ataaatcctc taagatgaga gttttttgtc ctaaaaagag
    17341 ctgcaccaac atcttctggc acagctctaa cagggggcaa tttatggaag tttgatgact
    17401 tgttctgttt ctttatcaaa gaagtggcct ttgctgatgt tgaaggcaag gtcgactatt
    17461 tcgcctggtt tatggaaatc tcttgcatct acttttgaga tgaactcagt agaaccagtt
    17521 tttgtgtaaa gcatcgtttc agctccaagt aattcggaaa cgacaacttc tgatttcact
    17581 acggcttcag gtgaagcttc aagggctact tgttcactgt ggatgtcttc tggacgaata
    17641 ccgaagataa cttcttttcc ttcataacct ttttcaacta atactttgtt ttttccttca
    17701 ggaatacgaa gcttaagccc atgtccatct gtgataacac catttttcaa tgtcacatta
    17761 aagaagttca tggcaggaga tccaataaag ccggcaacga acatattgac gggtgtatca
    17821 taaacttctt tcggtgtacc gatttgttgg ataaatccgt ctttcatgat aacgattcgg
    17881 tcagccatag tcattgcttc tgtctgatcg tgagtaacat agatggtcgt tgtttcaaga
    17941 cgctggtgaa gtttggcaat ctcagcacgc atggctacac gtaatttagc atctaaattt
    18001 gataatggct catccattaa gaagactttt gcatcccgaa cgattgcccg tcccaatgcc
    18061 acacgttggc gttgtccacc agataaagca gctggttttc gtttcaagta ttctgtcaga
    18121 cctaagatct ctgctgcatt gtccacacgt tttttgatgt ctgctttatc atatttacgt
    18181 aatttcaagc caaaagccat attatcaaaa acagtcatat gaggatacaa tgcgtagttt
    18241 tggaaaacca tggcaatatc acggtcttta ggtgccacgt cattcatgac ttttccgccg
    18301 atatttagtt ctccttcaga gatatcttcc agtcccgcga tcattcgcaa agtagttgac
    18361 tttccacaac cggaaggacc aacaaaaacg ataaattcac ggtctttgat tgatagatta
    18421 aaatcagtta cagaataatt ttctgcattg tcatattttt tatatacgtt tttcagagcc
    18481 atttctacca taatacgttc cacactttct tttttagttt tattaactat ttaaagtata
    18541 aatgaaagcg ttaactaact tcaatgtcat gttgaacaag aattttttct tttttttgtc
    18601 aatgtgctag ttttaag
//
LOCUS       DACCVZ010000055        18491 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.055, whole genome shotgun sequence.
ACCESSION   DACCVZ010000055 DACCVZ010000000
VERSION     DACCVZ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.055"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(100..1872)
                     /locus_tag="IVW63_001903"
     CDS             complement(100..1872)
                     /locus_tag="IVW63_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002841847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860173.1"
                     /translation="MRMQMIGGLTMKSFYKNKFALTNQGAEDLVKASISSFFVYCINM
                     VPAFIIMMLIDELVLENVKPPWLYFTVSFVTLLFMYWLLDREYENLYNSTYKESAHLR
                     MQIADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVM
                     LLVGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEI
                     NSFNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLL
                     TGEVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSP
                     LKSFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDY
                     DEGCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAA
                     RLANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLD
                     AENEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKIVDQGTHSELYRRSE
                     IYKNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(1826..3580)
                     /locus_tag="IVW63_001904"
     CDS             complement(1826..3580)
                     /locus_tag="IVW63_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860174.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLK
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(3690..4259)
                     /locus_tag="IVW63_001905"
     CDS             complement(3690..4259)
                     /locus_tag="IVW63_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HAP7860175.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(4277..5701)
                     /locus_tag="IVW63_001906"
     CDS             complement(4277..5701)
                     /locus_tag="IVW63_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP7860176.1"
                     /translation="MKELFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSG
                     KSTLLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTN
                     TTSELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLS
                     LNSKLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVK
                     NRTVKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDIN
                     FDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQF
                     FTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSK
                     TNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGG
                     IKKDIKLRVEDSTLIEQIFNDITK"
     gene            complement(5703..6371)
                     /locus_tag="IVW63_001907"
     CDS             complement(5703..6371)
                     /locus_tag="IVW63_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAP7860177.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(6502..7086)
                     /locus_tag="IVW63_001908"
     CDS             complement(6502..7086)
                     /locus_tag="IVW63_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7860178.1"
                     /translation="MESGLSHFEKVGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCIDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(7421..7651)
                     /locus_tag="IVW63_001909"
     CDS             complement(7421..7651)
                     /locus_tag="IVW63_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HAP7860179.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLTKLRYEDYLDIGFQLTDKGKKFIDDYKKRF"
     gene            complement(7666..8616)
                     /locus_tag="IVW63_001910"
     CDS             complement(7666..8616)
                     /locus_tag="IVW63_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAP7860180.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(8613..9455)
                     /locus_tag="IVW63_001911"
     CDS             complement(8613..9455)
                     /locus_tag="IVW63_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP7860181.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            complement(9588..10313)
                     /locus_tag="IVW63_001912"
     CDS             complement(9588..10313)
                     /locus_tag="IVW63_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP7860182.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGGTA"
     gene            complement(10774..11088)
                     /locus_tag="IVW63_001913"
     CDS             complement(10774..11088)
                     /locus_tag="IVW63_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAP7860183.1"
                     /translation="MHKDLLIICETGISASLLVSKMLETIRAKNLSYEIDYATIRNVE
                     EKLNYKDYDVLLLTPQVARSEEKVKEIIKKEKCTAQIVYIKQEDFRYMNIENIIASIE
                     ED"
     gene            complement(11104..12699)
                     /locus_tag="IVW63_001914"
     CDS             complement(11104..12699)
                     /locus_tag="IVW63_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HAP7860184.1"
                     /translation="MNLFSIISFLVIVICVWLFAYSRSRSVDTSGSEGFFMGGRSLTA
                     LPIAGTIIMTNLSTEQIVGQNGQSYHAGMEVMAWEVTATIAIVALAVIFLPKYFKYGI
                     NTISDFIEIRYDTVTKRIISILFIVTYMTSFLPVVLYSGSLVFNKIFHIDELLGVQPI
                     VAIIIVAMAIGIVGILYLLIGGLSLSANSDSIYGVGLLACGLLVPILGLMKLGDGSFV
                     GGIEHVVVNTPWLLNSVGSIDSAVVPWPTLFTGMLFNNLYFWCTNQMIVQKALSGKNL
                     AEAQKGAFLVGVFKILGALFLVFPGIVARNIFGDSLMSNPDNAYPFLVSEVLPKMIFG
                     IFAAVIFGAILSSFAGALNATSTLFSLDFYKPLINKKANDKQIARAGKTVTVVVGIIS
                     IIVAPFISFAPAGLYQFVQEFNGLYNMPLLVIILFAFYSKKATAFGAKTTIAVHIVLY
                     ALSKMLFQNIHFLYVLTALFVLDIIILMVVSKLKPDGEFVLNSFDTKVDIEPWKYTKV
                     TAIALVVIVILTYVAFSPIGFAG"
     gene            complement(12722..13612)
                     /gene="iolE"
                     /locus_tag="IVW63_001915"
     CDS             complement(12722..13612)
                     /gene="iolE"
                     /locus_tag="IVW63_001915"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015076872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HAP7860185.1"
                     /translation="MTKQIQLAIAPIAWTNDDMPELGSENTFEQCISEMALAGFTGTE
                     IGNKYPKDPEVLEQYLNIRGLKVASAWFSAFLTTKPFEETAEAFKAHRDFLHAMGAKV
                     IVVAEQGHSIQGIMTAPVFDDKPVFTDEEWKKLAEGLEKLGDLAHEKDMEIVYHHHMG
                     TGVQTTEEIDRLMEMTDPDKVKLLFDTGHLVFSGENPIAVYNRHQDRIKHIHFKDIRQ
                     ETAEEVEKEKDSFLNGVKKGVFTVPGDGMIDFTPIWTAIHASDYEGWIVVEAEQDPAK
                     ANPFEYAVKARSYIREVTGL"
     gene            complement(13629..14654)
                     /gene="iolG"
                     /locus_tag="IVW63_001916"
     CDS             complement(13629..14654)
                     /gene="iolG"
                     /locus_tag="IVW63_001916"
                     /EC_number="1.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase"
                     /protein_id="HAP7860186.1"
                     /translation="MNNIRVGIVGLGRLGKVHAQNLATGVSCCELTAACSLVETELAF
                     AQKKLGVKHTFSSYEEMVKSSVIDAVFIVSPSGFHCDQVRLAMENGKHVFTEKPLGLE
                     VEDIKKTQKVIEEHPEQVFMLGFMRRYDESYQYAKKMVEDGEIGEITLIRCYGIDPSE
                     GLESFVKFAMNNDSGGLFLDMAIHDIDLVRWFTGQEVDQVWAIGKNAAYPELDQAGEL
                     ETGAAMMSLSDKTIALLVAGRNAAHGYHVETEIMGTKGMLRVAQAPEKNLVTIMNDQG
                     IIRPCSQNFPERFREAFIREAQEFVSCIQEKRQPAVNAEDGLQSTKIALACQESFDTK
                     SLVQLKK"
     gene            complement(14678..15685)
                     /locus_tag="IVW63_001917"
     CDS             complement(14678..15685)
                     /locus_tag="IVW63_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP7860187.1"
                     /translation="MRVKVGVIGTGAIGIEHIDRINQKTQGAYVTAVSDINVKAAKEV
                     AKRVDAKFFETGEALIASEDVDVVVVTSWDPTHEQYVLEAIKHGKYVFCEKPLAMDAA
                     GCRRIVDAEVAYGKKLVQVGFMRRYDRGYIELKEAIESKQYGEALMMHCAHRNPSADE
                     NYTTPMAISNTAIHEIDVLRWLLNEDYESVQMILPKKTSNSHADLHDPQLLIFQTKSG
                     VTIDLEIFVNCRFGYDIKCDVVFETAEVGMTDPAYTRIKSEEKNYTPVSPDWQTRFLD
                     AYDYEFKLWIDSIKNDAVVGPTAWDGYVAAITMMACHESRETKTKVMIQMDERPALYN
                     E"
     gene            complement(15798..16958)
                     /locus_tag="IVW63_001918"
     CDS             complement(15798..16958)
                     /locus_tag="IVW63_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HAP7860188.1"
                     /translation="MNIQLKMPANLRIGGGTIQFLMEESEQLGNKPLIISDTVMEQTG
                     HLQKIKELLGKTDDQLAEYTDIQAEPTQENVYDALKLFQKHQCDHIIAFGGGSCLDTA
                     KVVAVLAANQLSLEAIHARNFDQLQAGIPLIAVSTTAGTGSEVTDVAVITNTKTAVKM
                     MMKDLVFMPQISIVDSDFTKTVPPKVTAATGVDALCHALESYVSVKANEVTQLFSLEA
                     MKKILNTLSQAYENSDDTEAREQMSLASTEAGIAFSNASVTLIHGMSRPVGALFHIPH
                     GISNAMLLPVFFEFSKDAIQTELATIARFIYPAAEDLSLEEAADYLIKKIQELCEQLS
                     IPTIRDYGIDQQAFMAALDKMAADALTSGSPQNNKKVPSHSQIKELYVQAYG"
     gene            complement(17034..18488)
                     /locus_tag="IVW63_001919"
     CDS             complement(17034..18488)
                     /locus_tag="IVW63_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010825391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="HAP7860189.1"
                     /translation="MTRFLRNYIDGRWVASRSTEFEEVMNPATEEALANVPLSSKAET
                     AEAVKAADAAFQTWKKVPVPVRGRYLFKLHQLLTDHKSELARLITLENGKSLSESLGE
                     VQRGIENVEHAAGITNLMMGDSLSTAATDIEITNYRYPIGVIGGITPFNFPMMVPFWI
                     FPMALAAGNTVVLKPSEKTPLLMEKIVELVEKAGFPSGVFNVVYGAHDVVNTLLQDPL
                     VKGISFVGSKNVGEYVYREGTKNLKRVQALTGAKNHVVVLKDANIDRAVKDLIGGAFG
                     SAGERCMAASVIVLEEEIADQFVEKFKAAAKAIKIGNGLDEGVFLGPVIRKDAQQRTF
                     DYIQKGVDEGAKLVLDGRENIPEKGYFVGPTIFDNVTMDMKIWQDEIFAPVASIVRVK
                     DLMAAVELTNESEFANGSCLYTNNASAIRYFRENVDAGMLGVNLGVPAPMAWFAFSGW
                     KHSFFGDLHANGKDSVEFYTHRKVVTARYAQSEI"
BASE COUNT         5705 a         3848 c         2879 g         6059 t
ORIGIN      
        1 gtgtattcaa aattagatgc tgtttaataa aattattctt tttgaaaaag aattataact
       61 atatcccaaa aattgtaggt taatttaaag cctatttcat catcgtgatt gagcttcttt
      121 ttcatagacg aatttctcag atagtttagt tttctttatg agatttttgt atatttctga
      181 ccttcgatac aactcactat gagtaccttg atcaactatt tttccttgat ccatcactac
      241 aattttattt accttttcaa tagacttcaa gcgatgcgat ataattagta ctgtcttatc
      301 ttgtattaaa cgatttaaac tttcctgaat acgtttttca ttttccgcat ctaaactggc
      361 agtaatttca tctaaaatta aaattggcgc atttttcaaa aaagcccgtg ctatggatag
      421 gcgttgtcgc tctcctccag aaagtgaact tccgttttct ccgaccaatg tatgataacc
      481 gtcaggtagt ttttcaataa agtcttcgca gttagctaaa cgagctgctt ttttcacttc
      541 ctcatctgac gcttgactat ttccaatacg tatattttcc aaaatacttg tattaaacaa
      601 agttacctct tgaaaaacaa tagcgatttt gctaaacaaa gaagctggag atacacgttt
      661 aatatcatac ccatcaatta aaatacagcc ttcatcataa tcatacagtc tagacactaa
      721 tttcaagata ctagttttcc cggaaccact agcacctact aacgcagtca cttctccttg
      781 tttagccgta aaagagatat gatctaaaat tggggtattg ttatcatatg agaaagagac
      841 atctcgcaac tcaatgtcaa aagatttcag aggactatct gatccctctt ggatactggt
      901 ttccttcata gctctaattc gctgtatttt aggagctaaa taaaatattt caagcactgc
      961 ttctttcata gaatcgaagg aatcctttat ttttattgcg gctagtaagt aaccaacgac
     1021 gtagagtata gtcacttcac ccgttaacag taagtgaaca cctactagaa tgactactgc
     1081 taaactaaca tatgagaaaa tagaggataa ggccatgact gaaaaagtac ttaattctac
     1141 ctttaaatga atcctttcac tctcttccat ttttttgaaa agtctgtctt gaactttttt
     1201 agatagatta aagctattaa tctcttgctg caattctata gtttcttgaa attcttccga
     1261 gttttctctc aaagtatcgt aatatttagt attggctttc gtttgggatt tctttgataa
     1321 caagattaag acaaaactaa ataacgttgg caaaataaca gctaatccca ttttgacatt
     1381 accaaccaaa agcatcactg aaataaaagg gaaaaacaga gccataccgc cggctttagg
     1441 tattgcatga ctcatcgcat gctcaatacc ttcaacgtca gacatgatag tttgagataa
     1501 atctgataaa ttatgttttg aaaaatagga taatggtaaa tttgacaaat cgtctgcaat
     1561 ttgcattctt aaatgcgcac tttctttata agtactatta tataagtttt catactccct
     1621 atctaacaac caatacatga aaagcaaagt aacgaacgat actgtaaaat aaagccaagg
     1681 cggctttaca ttttctaaaa ctaattcgtc tatcagcatc attataatga atgctggtac
     1741 catattaatg cagtatacaa aaaagctaga aatagatgct ttaaccaaat cttctgcgcc
     1801 ctgattagtt aaagcgaatt tgtttttata aaaacttttc attgtcaagc ctccaatcat
     1861 ttgcattctc ataattagtg accaattgtt tatacacttg atgtttagcc attaattcat
     1921 tatgatttcc acgttctact attttccctt ctgacaagac aagaatttca tctacagatt
     1981 taatgctgga taatcgatga gctatcataa taactgtttt ttctttcatc agatgttgaa
     2041 aagccttttg tagttcatac tcattatctg gatcaataga tgcactggct tcatccataa
     2101 taacaatctt tgcatctttt aaaattgctc tggcaatagc tatacgttgt ttttctcctc
     2161 ctgacagata aactccttta ctaccaatta aggtatgctc tctttcggga aatttttcta
     2221 aaatcgattc gcaaccggct aatcttagcg cgtcaaatac tttacttgct ggcgcttgag
     2281 gatttgctat agaaacgtta tcgtaaatac tctgattgaa tagtttcgta tcttgaaaga
     2341 caaaagcaat tgtgttaata attgtgtctt ttgaatagtg atttaaaggc ttaccaccaa
     2401 ttttaatctg tcccttatcc acattgtaga aacctgaaat tagtttagct atcgtactct
     2461 ttccgcttcc tgattttcct actaatgcat aaattctttt ttgttctaaa actaagttga
     2521 aattttctaa aacacactct tctttgtatg aaaagctgac attttcaaat gcaatgtcac
     2581 aatttttaat ctgtgtctcg ttcccatatt ttagttggtc ttgcttcatt tctaaataaa
     2641 gggagtctag tgtttcgact gcatatcttg cttcaaacaa gtgcatactt acatacatta
     2701 ttctcatgaa agaaacaaaa ataattccac ttaaaaaaaa caacatcaac aagtcaacag
     2761 ctaatatctt gggagtggta agagaagtta taaaaaaggt tataggaact atcaaaatgc
     2821 aaactatgcc aaaaaatagc cattgaaaaa gaacaaaagg tgttttccca ctcaaagaat
     2881 acttatatgc aaacttagca taatcgttaa ttgctttatt caaggcttta aatgatgtta
     2941 ctttagcacc aaatatcttt ataacttgaa ttcctcggat atattctacc gtttcagagc
     3001 ttaacacatc taacgattct tgatattttt gaataaaatt tgtattctct gtcattttct
     3061 ttaacaagaa tacaccaatt actaacatgg cgattagaac caatccaatt ttaaaattaa
     3121 tgaaaaagcc taaggcaact gataaaacag gtgttactat ggcttgagca ctatctggaa
     3181 tcaagtgagc aattgccata tgtgttttag ccgcgttgtc atcaattgtc tttcgaatat
     3241 atcccgaaga atttaaatca aaaaaacgaa aacttgcttc tgttaaaccg ctaattccct
     3301 tttttctcaa attagtctct aagcgaaacc caaggatatg agaaaataag ccagaaaaaa
     3361 tataaaataa agctcctaaa gttaaccaag caacagtttg aaccgcataa ctcttagcta
     3421 aatattcatc tcctacaata attagagact taagaaattt gtaaatactg taatatccat
     3481 agactgttaa tacgacagaa aaatcagaaa ataaagtggc taaccatccg tagtatttca
     3541 ttttagggac ataactaaat aattttttgt atactttcat tttttcctcc cccgcattca
     3601 atttcttctc ttattcgttt acaactgtta atgctttccg taatagcgta aattagagat
     3661 gtacaaacag atagaaggta aactacgttc tattttttgt atttttttaa gacttttctt
     3721 ccaatcaata caccaatcat agataaactt gctacaacta acactgaaat gattccccat
     3781 atacctaccg catagtggat cattgcatcc attgttgcag cagattgtcc tttatctatc
     3841 caatcttgac gaaaacgatc tgtaaagaac catataggaa tccactgtcc ggcagcactg
     3901 cctaattgca ttagagccca agacgcaact tgaggaattg ctcgatcata tccaaataca
     3961 gatagaataa tatcagctaa gatcgccata ctaatcgaac tgataaacca aggtaagtac
     4021 gccccgccca ttaacgtaaa aaataacaat aaaacaattg tgtaaatagt aaaaattcct
     4081 tttctagggt agttatagct aatataaaca aatatgattc cagataataa tccaaaaatc
     4141 cctggggata tgctgtgacc aaacgcccca ccaatactac taaccattat tgaaaaaaag
     4201 taaattacta gggaaataac tgtagctaaa ccaataaaaa tataatcttt tgttttcata
     4261 tatattctcc tcaattctat ttcgttatgt cattaaaaat ctgttctatc aaagttgaat
     4321 cttctactct aagttttata tcttttttta ttccaccatt ttttaaataa ataattctat
     4381 tgcatgtttt ataaagaaat tccggatcat gagtggctat aactactgca cccttttctt
     4441 ttaagtcttt aataaggtca gcaatccttt ccatattaat ataatccaac ccacttgtag
     4501 gttcatcaaa tagaaataaa ttagtttttg acaatgaagc tatagaaacc aataatcttt
     4561 gtttttctcc accggataaa tcaaacggta attgatcttt cattttataa agttccattt
     4621 tttttaaaat tttttcttgc tgatctttac taactatttc attccccagg gctaactcgc
     4681 tcctcactga ttctgtgaaa aattggtaat ccatttcttg cattactaaa aacggcgatg
     4741 acaaattttt tttattttcg attatctttc ctttggtagg gcgaataatc ttcatgagta
     4801 ttcttagtaa ggttgttttc cccacaccgt ttttccctac caaaccaata acatctccaa
     4861 ctttgacatc aaaatttatg tcttttagaa tattttcata agtaatttct tcaactttta
     4921 atacatctgc acttaccttt tcgatatagg gaacttcaat cgaactatta aaaatgtcaa
     4981 atttccttaa tgcgttattg ttttcagttt ttaacaactg aatagttgta gtttttacag
     5041 ttctattttt aacaaataga acttgatcaa ttaattcttt caaatagtaa aaacgatgtt
     5101 cagctataac aatagtaaat cctttatttt ttaaatcaca aagtaagtca gcaagtttct
     5161 tagtcgcttt gaagtccaaa tttgaagacg gttcatccaa tataattaat ttagagttta
     5221 gcgataaact acatccaata gaaattttct gccgttcacc acttgatagc gaaaaaatgt
     5281 ttttatctaa tatatttgaa agatctaata attcagctaa ttcattgatt cttttatcca
     5341 tatgctcttt tgtaaatcca aagttttcca tcgaaaatac taactcactc gttgtatttg
     5401 ttgtaaagaa ttgtcctcta ggatcttgac ttacgtagcc aatatttttt gatatacttt
     5461 cttgtgttaa ggattgtagc gagttatttt caaataaaat ttccccaacc aattttccgt
     5521 cataaagtct tggaataagt ccattcatta actttaatag tgtggatttc ccactcccag
     5581 aagaaccagt aatcaatgta agactacctt tttttattga aaaattaagg tcaacaagcg
     5641 cttgttcctt aacatcctta tatgaaaaag aaacattgtt aaattcaaac aattctttca
     5701 cctcaaatca aaatacttaa gaaaaaaata gtaacggaaa acaggatgat atagtctaat
     5761 aagctcatgt ttgttttata gtaagaactt cttttcacag gagattctat cccctttgtt
     5821 attgcattag cggtcatttc ttcagcaatc atagttgcac gtataagaac gggaactaac
     5881 agaaattcca aatattgcag aggctgaaaa aaagacaagc gaatgtttct catttttaaa
     5941 gattctttaa tcattcttat ttcagaacga taagtcggaa agaatctgat cactactgta
     6001 atacttaaca ttattttttt cggtaaatgt attttttcta aagaggataa taattcattg
     6061 ctagtataga cactaaccaa caaccatgag atcattacga ccggcaacat tcgaaataca
     6121 atatataagg atgtcccaaa aaatatagta aaaaactcta tcttgatagc atcaataatt
     6181 ttcattacta aaaacagaac tgaataaatc aagatgaaat aaatacatgt ctttatttta
     6241 cgaaacatca atactaaaac tgtagcaata atgaaacacc ccacttgaaa tatatttccc
     6301 tttcctaaaa aaataatgac cggaaaaaaa atatttaaag taatcaaggt taacggattg
     6361 atttttgaca ctctttcacc tccaaaaaat aagatcgcac tgttatctta agctgataaa
     6421 aatgcaccgt tattcagata acagtgcgat cttatcaaaa agcataactg agaacaattc
     6481 tcaatgcaag ctttttttta attaactcag taattcaatc cacccaggaa cagaaaattg
     6541 atacaatctt ctggttaata gcatagtctt ttcttttgaa tagctatgct tcaatatatc
     6601 atagaatgta gcgtagaatg agtaaatgta gaagtggatt tcttcttcat taaagactaa
     6661 attttgattg atcattccga tagtctttaa cttatctata caacagactg tcttttttgt
     6721 cacaaatgat gtaatttttt caacaatatc ttgatatttg gttccagctg attggaataa
     6781 aaccaaatcg aatatacgtt tattctcaaa aatataatta ataaatggat ctaattcatt
     6841 gaagttctct ctccaacttt tctctatatc tatattttct aagtttaaga ggtatttggt
     6901 aaactcttca ttatacatat taataagcgc attaatatgc ggctgaataa tttcttcaaa
     6961 taacgcttcc ttagaagtaa aatgtttata aaaagcaccc gtagttacgc ctgcggtcaa
     7021 gcacagttgc cttatcttag tttgctgaaa tcctactttt tcaaaatggc ttagtccact
     7081 ttctattaat ttttggtgag ttgtaatata atctctggtt tctatgggta cttcctccta
     7141 ataagatgaa ttaactatat tatcttacac aggacttgaa gtttcaatcg ttaacgtcta
     7201 ttactgaact cattccttag agctaaacta atgagaaaga gcaaaataac tgatacaaaa
     7261 agcaatccta caagaattaa tagactcatc taaatcattc accttttcta aaataatccg
     7321 agaaagattt aaaaaaatta tatccagcta ttaggataag tcctatcata atcactccaa
     7381 tagccatttt cttatcctcc ctaaaaataa agccttttac ttaaaacctt tttttgtaat
     7441 cgtcaataaa ttttttccct ttatcagtta attgaaatcc tatatctaaa tagtcctcat
     7501 atctaagttt agtcagcatc tcacttacag atgctggact aacacttaga acttttgcta
     7561 aatcattatt ttttaatttc ttttttcttt ttgataattc ctgaattgct agtaaataaa
     7621 ttagtatagt agttgtttta atttgtacca tacctaccct ccaaattatt tcgaaaggcc
     7681 ttcagcaatt ttatccaggt tccatttcat catcgcatag taactatcac catcttgtcc
     7741 tttttctgca attgaatcag taaaaatcgt tgaatagata ggaatattgg tatcttttga
     7801 tactgttttc attggtctat cgtccacact gctttctacg aataaggagg gaacttttgt
     7861 tgtgcgtaat ttttcaacta agtgttttat ttgatctggt gttccttctt cttcagtgtt
     7921 gatttcccaa atgtaagcag aaggcacatt atacgctttc gagaaatatt taaagcatcc
     7981 ttcacttgta acaatcattt ttttatcatt cggaattgaa gcaaatttag atttagcttc
     8041 tttgtctaga gaatccaatt tttcaatata cttatctaga ttttctttat agaatttttt
     8101 attatcagga tctttttccg ctaactgttt ttcaatattt ttagcgtaaa taataccgtt
     8161 ttctaaattt aaccaagcat ggggatcttc cttccctttc tcactctgac cctctaagta
     8221 aataacatct atgccatcac ttgctgcaaa atagtctttg ttttcctctt tgttcgcatt
     8281 ttttactaat tttgtaaacc aagcatttcc tccagtttcc aagttaacac cgttataaaa
     8341 aatcaaatct gcttttgaag ttttttgaac atcttcaggc aaaggttcat attcgtgggg
     8401 atctttccca ataggtacga tactgtgtaa atcaatttta tcttttgcta tattttcagt
     8461 aatatctgct aaaatcgaat tagtaactac tacctttaat ttttcgttcg aagccactgt
     8521 atctttgtct ttactatttg ttgaacatgc cccgaatata aaaagagcaa tcaaaatccc
     8581 cagacttccc agtactgctt tccattttct catcataact ttctctcctt ctttcttaaa
     8641 aatttttgtt ttggtgagat tagaaaacta attacaaata agaatgccgc tgttaaaaca
     8701 atacttgatc ctgctgctat gttaaaacta taaccaatga acaaacctag caatgatgag
     8761 cacgctccga ctgtcgccga aataaatatc atagttttta aactgtttgc atataaatat
     8821 gctgtagcag ctggtgtaat taacattgca acaattaata tagttcccac actttgcata
     8881 gctgttactg ctactaaagt taatagaatc attaatagat aatgataaaa actgacattc
     8941 atccccattg cttttgccat taatggatca aaagaagtga ttaataattc tttaaaaaat
     9001 agaacaactg taaccaacac taaaacagaa acgccaattg taatccactt atcaatatct
     9061 tgtacagcta aaatatttcc aaataagata tgaaataaat ccgttgagct atttgcaact
     9121 cctataagga taactcctaa tgctaaaaaa gaactgaaag taataccaat tgctgtatct
     9181 ccttttatta cactattgct ttttataaaa gtaataatga tagaagctaa tagaccaaat
     9241 acaatcgcac caataaaaaa attaatacct aaaatataag aaattgctac tcctggcaaa
     9301 acagcatgag aaatagcatc acccataaga gacattcctc ttaaaataat aaaacaacct
     9361 actgttccag aaacaatccc tataactaca gatgtaatta gagcattctg taaaaagtga
     9421 aagtcataca gaccattaat aaaattttga agcatattat tccccttgta tattagagtt
     9481 agggttttaa ccttccggtt ttgattggat aaccctatga accatcgtta ttttaatttg
     9541 gtattaactc atttcttttg agataatata tttattggat tgagaggcta agccgttccc
     9601 ccctctccaa taaatatagt atctccatag gcttttttta aattctcttc attaaataca
     9661 gattctacac ttccgtgagc aattagattt cgattcaaaa gaataatatt atcaaaatac
     9721 ttctttacct tgcttaaatc atgatgcaca attagcactg tttttccctg atgtttcaat
     9781 tcttttaacg tatccataat tattcgttca ctaactaagt ctatccctac aaatggttca
     9841 tctaaaaata tgaaatccgc attttgagca agacatcttg ctaaaagtac acgttgaaat
     9901 tgtcctccag ataattctcc tatttgatga ttagaatatt ttcccatatc gaccttttcc
     9961 aaagcctttg aaactctttg ccattctgca tttttaattc tttgaaaaac tttcattccg
    10021 gcatatgttc ccatagatac acattctttt acttttattg gaaaagtaaa atcaatatca
    10081 gctttttgct ctacatatgc aatcttcacc agttttttat tgatatcttc attattaatg
    10141 gagacctctc cctgatgagg gataatattt aacattgctt taagcaatgt agattttcca
    10201 gcaccatttg gaccaataat acctgttaaa gcaccttctt gtatttttaa agaaatctcg
    10261 ttcaatgcta aaaaatcgtt ataacaaaca ttaagctttt tcacttctaa cataactttc
    10321 tccttctaaa tgataatgat tatcacgatc atatggtata caaaaattat attttagtca
    10381 accctaaatt ttataattta gatttttttc tgttgttgaa gattaggatg tcaaaattat
    10441 ttgaaactac tcgtatagta aatagtaagt aattttcaaa acacgaagaa aaacaaaaag
    10501 aaaaaaggaa acgccgaagc atttcctttc agtgatttaa tgagaacaac acgatttgac
    10561 ttagagtctc aaaaagtcga ataggtacac tcatttaagt gtctccattc gactttttgg
    10621 ggatgagctg gctattgagg tccgcttacc ctattgaata aatacaagat tgggtatttc
    10681 taataagtcc gcccttcata ttggggtgat cggggcgaac atgccatctt ttcatatacc
    10741 acctcctcga cactcaataa tcaaagattc tcgttaatct tcttcgatgc ttgcaatgat
    10801 gttttcaata ttcatataac gaaaatcttc ttgtttgata taaacgatct gagcggtaca
    10861 tttttccttt ttgatgattt cttttacttt ttcctcagaa cgtgcgacct gcggcgttaa
    10921 aagtaaaacg tcatagtctt tataattcag tttttcttca acgtttcgga tcgttgcata
    10981 atctatctca tacgatagat ttttggctct gatcgtttca agcatttttg atacgagcag
    11041 cgacgcactg attccggtct cgcaaataat caatagatcc ttatgcataa taccctcctg
    11101 tttttagcct gcaaagccaa ttggtgaaaa tgccacataa gttaaaataa caatgactac
    11161 caatgctata gcagtcacct tggtgtattt ccaaggctcg atatcgacct ttgtatcgaa
    11221 tgagttcaac acaaattctc catcaggttt caatttggaa accaccatca aaatgataat
    11281 gtccagaacg aataatgccg tcaaaacata aaggaaatgg atattttgga aaagcatttt
    11341 tgatagtgca tacaagacga tatgcacggc aatcgtcgtt tttgccccaa aagcagttgc
    11401 tttttttgaa taaaaggcaa agagaatgat cacgagcagc ggcatgttgt atagtccatt
    11461 gaattcttga acgaactgat acaatccagc cggtgcaaaa gaaatgaatg gcgctacgat
    11521 aatggagata atccccacaa cgaccgttac tgttttacca gcacgagcga tttgcttatc
    11581 atttgctttc ttattgataa gcggtttata aaaatccagt gaaaacaagg tcgatgtcgc
    11641 gttcaaagct cccgcaaatg atgataagat cgcgccaaag ataacagcgg cgaaaatacc
    11701 aaagatcatt ttaggcaata cttcactgac taaaaaagga tacgcgttat ctggatttga
    11761 cattaaacta tcgccaaaaa tattgcgagc gacgatccct ggaaagacaa ggaataacgc
    11821 acctaagatt ttgaagacgc cgactaggaa agcgcccttt tgtgcctcag ctaaattctt
    11881 gccggacaat gctttttgga cgatcatttg attggtacac cagaaataca gattgttaaa
    11941 cagcatccct gtaaatagtg tcggccatgg aacaacagcc gagtcgatcg atcccacaga
    12001 gttaagcagc catggcgtgt ttaccacaac gtgttcgatc ccgccaacaa agctgccgtc
    12061 accaagcttc attaagccta aaattgggac cagcagacca caagccagca gaccgactcc
    12121 ataaatggag tcactattgg cacttaacga caagccgccg atcagcagat agaggatgcc
    12181 gacaatacca attgccatcg ctacaattat gatcgcgacg atcggctgga cgcccagcag
    12241 ctcatcaata tggaagatct tattgaacac cagcgatcca gaataaagaa ccacgggtaa
    12301 gaaagaagtc atataggtca caataaataa gatcgaaata attcgtttgg taaccgtatc
    12361 ataacgaatc tcgatgaaat ctgagattgt attgatgccg tatttaaaat attttggcaa
    12421 gaatatcaca gccaaagcta cgatcgcaat cgtagcagtt acttcccagg ccattacttc
    12481 catccctgca tgataacttt gaccattttg tccgactatt tgttcggtgg acaggttcgt
    12541 catgatgatc gtgccggcga ttggcaaagc agttaagctc cgccctccca tgaagaaccc
    12601 ttctgatcca gaagtatcga cacttctgga tctagaatag gcaaataacc atacacagat
    12661 gacaatcact aggaaactga ttatagaaaa aagattcatc gtctagctcc ttttcaatag
    12721 attaaagacc ggtgacctct cgaatgtagc ttctggcttt gactgcatat tcaaatggat
    12781 tggctttagc cgggtcctgt tctgcttcaa ctacgatcca gccttcatag tcgctggcat
    12841 ggattgctgt ccagattgga gtgaaatcaa tcatcccatc accaggaacc gtgaagacgc
    12901 ctttcttcac gccgtttaag aagctgtctt tttccttttc tacttcttca gccgtttctt
    12961 gacgaatatc tttgaaatgg atgtgtttga tacgatcttg atgacggttg taaaccgcga
    13021 ttggattttc accagaaaag accaaatgtc ccgtatcgaa caataattta actttgtctg
    13081 gatcagtcat ttccattaaa cgatcgattt cttccgtcgt ttgaacgccg gtacccatgt
    13141 gatgatggta aacgatctcc atatcctttt cgtgggccaa atcccctaat ttttctaatc
    13201 cttccgccag ttttttccac tcttcatcag tgaaaactgg tttatcatca aagactggcg
    13261 ctgtcataat cccttggata ctatgaccct gctcagctac tacgatgact ttagcgccca
    13321 tcgcatgtaa gaaatcccga tgtgctttga aggcttcggc agtttcttca aaaggtttag
    13381 ttgtcagaaa cgcactgaac catgcactgg caacctttaa gccgcgaata ttcaaatatt
    13441 gttccaacac ctctggatct tttggatatt tgttgccaat ctctgttccg gtgaacccag
    13501 caagggccat ttcactgata cattgttcaa aggtattttc actaccaagc tcgggcatat
    13561 catcattggt ccacgcgatt ggtgcgatgg ctaattgaat ttgtttggtc atattctcac
    13621 actcctgctt atttttttag ttgtactaaa ctcttcgtat cgaatgattc ttgacaagcc
    13681 aacgcgatct tagttgattg caatccatct tctgcattaa ccgctggttg acgtttttct
    13741 tgaatacatg agacaaattc ttgggcttca cgaatgaagg cttctctgaa tcgttctggg
    13801 aagttttgtg aacatggacg gatgatccct tgatcgttca tgatcgtcac aagatttttc
    13861 tcaggcgctt gcgctacccg cagcattcct ttggttccca tgatctctgt ttcgacatga
    13921 tagccatggg ctgcgtttct gccggcaact agtaaagcta ttgttttatc gctcaggctc
    13981 atcattgcgg ctccagtttc aagctcacca gcctgatcca attctggata cgccgcattt
    14041 ttcccaatcg cccacacttg atcgacttct tggccggtaa accagcgaac caaatcaata
    14101 tcatggatcg ccatatctaa gaacaagccg ccgctgtcgt tattcatggc aaatttgaca
    14161 aagctttcca agccttcgct cggatcgatc ccataacaac gaatcagtgt gatttcgccg
    14221 atttcgccat cttctaccat tttcttcgca tactgatacg actcatcata gcggcgcatg
    14281 aagcctaaca tgaagacctg ttcaggatgc tcttcgatga ctttttgggt ctttttaata
    14341 tcttcaactt caaggcctaa tggtttttca gtaaagacat gcttgccatt ttccatcgcc
    14401 aagcggactt ggtcacagtg aaagcctgat ggtgaaacaa taaagactgc atcgatcacg
    14461 gaacttttga ccatttcttc atagctggaa aaagtatgct tgacgcctaa tttcttctgt
    14521 gcgaatgcta attctgtttc aactaaactg cacgcagccg taagctcaca acaactgaca
    14581 cctgttgcta aattttgtgc atgtactttt cctaatcttc ctaaaccgac gatgcctact
    14641 ctaatgttgt tcatgaaata cctccgtttt ctgagaatta ctcattgtat agtgctggtc
    14701 gttcatccat ttgaatcatt acttttgttt ttgtttcacg agactcatga caagccatca
    14761 tggtgatcgc tgctacatac ccatcccaag cggtaggacc gacaaccgca tcatttttga
    14821 tcgaatcgat ccacagcttg aattcataat cataggcatc caaaaagcgg gtctgccaat
    14881 ctggtgaaac aggtgtgtaa tttttttctt ccgatttaat tcgtgtatag gctgggtccg
    14941 tcattcctac ttctgccgtt tcgaaaacca catcacattt aatatcgtag ccaaagcggc
    15001 aattcacaaa gatttccaaa tcaatcgtta caccggattt tgtttgaaag atcagcagct
    15061 gcggatcatg caaatcggca tgggagttgc tggttttttt cggcaagatc atttgaacag
    15121 attcataatc ttcatttagc aaccagcgaa gcacatcaat ctcatgaatc gcggtgttgc
    15181 tgatcgccat cggtgttgtg tagttttcat ctgcgctagg atttctatgg gcacaatgca
    15241 tcattaatgc ttctccgtat tgcttcgatt cgattgcttc tttcagttca atgtagccgc
    15301 ggtcatagcg gcgcatgaag ccaacctgaa ccaatttctt cccataagca acttccgcat
    15361 caacgatccg gcggcagcct gctgcatcca tcgctaatgg cttttcgcag aaaacatatt
    15421 tcccatgctt gattgcttct aacacatact gctcatgggt cgggtcccaa gaagtcacaa
    15481 caacgacatc cacatcttca gaagcgatca atgcttctcc ggtttcaaag aatttagcat
    15541 cgacacgttt ggcaacctct ttagcagctt ttacattgat atctgagact gctgtcacat
    15601 aagccccttg tgttttctga ttgatcctgt cgatatgctc gatgccgatt gcacctgttc
    15661 cgataacgcc tacttttact ctcaattact tatccccctg ttctgttgtt taagcacaca
    15721 tagtatgcgc ttacaaaatt attcctgtgt agcttttatt cttaaaaggt agagccctct
    15781 ctttgctccg ccttttacta cccataagct tgtacgtata attccttaat ttgactatga
    15841 ctaggcacct ttttattatt ttgcggactt ccgctggtca acgcatccgc ggccattttg
    15901 tctaaggctg ccataaacgc ttgctgatca ataccataat ctcgaatcgt tgggatcgac
    15961 agctgctcac agagctcttg gattttttta atcagataat ccgcagcctc ttccagcgat
    16021 aaatcttcgg ctgccggata aataaatctg gcgatcgtcg ctaactcagt ctgaatagca
    16081 tcctttgaga attcaaaaaa gaccggcaat aacatcgcat ttgatatccc atgaggaatg
    16141 tgaaaaagtg cccccaccgg tcgactcatt ccatgaatca atgtgactga cgcattcgaa
    16201 aaggcaatcc ccgcctccgt tgaagctaag ctcatttgtt ctctggcttc agtgtcgtcg
    16261 ctattttcat atgcctgaga aagcgtgttc aaaattttct tcatcgcttc cagtgaaaat
    16321 agttgcgtta cttcattggc tttgactgaa acataagatt ccaaagcgtg acatagcgca
    16381 tcgactcccg ttgccgcggt tacttttggt ggtacagttt tcgtaaaatc agagtcaacg
    16441 attgagatct gtggcatgaa aacgagatcc ttcatcatca ttttgactgc tgtttttgta
    16501 ttggtaataa ctgccacatc ggttacttcc gaaccagttc cagcagttgt tgacactgca
    16561 atcagcggaa tgcccgcttg cagctgatca aaatttcttg catgaatcgc ttcgagactt
    16621 aattgattag cagccaaaac ggctaccacc ttggctgtat ccagacagct gccgccacca
    16681 aaagcaatga tatgatcaca ttgatgcttc tgaaaaagct tcagcgcatc ataaacattt
    16741 tcttgcgtcg gttcggcttg aatgtctgta tactccgcta attgatcatc tgtttttccc
    16801 aacagctcct tgatcttttg aagatgcccg gtctgttcca taaccgtatc actaatgatt
    16861 aacggcttgt tgcctagttg ttctgattct tccataagaa attggattgt tccgccgcca
    16921 attcttaaat tggcaggcat tttcagttga atattcacag aaaaaacctc tctctggctt
    16981 atagcctata acagaatcct cgaagctctt taacagagct tcgaagcaaa tctttaaatc
    17041 tcactttgcg cataacgtgc tgtaacaact ttccgatggg tataaaactc aacactgtct
    17101 ttgccattgg catgcaaatc accaaagaaa gagtgcttcc agcctgaaaa ggcaaaccaa
    17161 gccatcggtg caggcacccc aagattgacc cccagcatcc cagcatcaac attttctctg
    17221 aagtagcgaa tcgctgatgc gttgttggta tacagacacg aaccattcgc aaattcagat
    17281 tcattcgtca gctcaacggc tgccatcaaa tcttttaccc gcacgattga tgcgaccggg
    17341 gcaaaaatct catcctgcca gatcttcata tccatcgtga cattatcaaa aatcgttggt
    17401 ccaacaaaat agcctttttc tggaatgttt tcgcgaccat ctagtaccag tttcgctcct
    17461 tcatcgaccc ctttttggat atagtcaaag gtccgctgct gtgcatcttt tcgaatcact
    17521 ggtcctaaaa agaccccttc gtccaagcca ttgccgatct tgatcgcttt tgccgcagcc
    17581 ttaaattttt caacaaactg atccgcgatt tcctcttcca aaacaatgac ggaggctgcc
    17641 atgcagcgtt caccagcaga accaaaagct ccgccaataa ggtccttgac tgcccgatca
    17701 atattggcat ctttcagcac aacaacatga tttttcgctc cagtcaacgc ttgtacccgt
    17761 tttagatttt ttgttccttc acggtaaacg tattcaccga cattttttga tcctacaaag
    17821 ctgatgcctt ttaccagtgg atcttgcagc aatgtgttga caacatcgtg ggcaccatag
    17881 acaacattaa aaacaccgct aggaaagcct gctttttcaa ccagctcaac aattttctcc
    17941 atcaacaatg gtgttttttc tgaaggcttc agcaccaccg tatttcctgc cgccagagcc
    18001 atcgggaaga tccagaaggg caccatcatt ggaaaattaa acggtgtgat ccctccgatt
    18061 actccgattg ggtaacgata attcgtgatc tcaatatcag tcgccgctgt tgataaagaa
    18121 tctcccatca ttaaattggt gattcccgct gcgtgctcca cattttcgat tcctcgttga
    18181 acttctccca gtgactcgga caatgatttc ccattttcca gcgtgatcaa acgcgccaat
    18241 tcacttttat gatctgttaa aagctgatgc agcttgaaca gataacgtcc gcgaacagga
    18301 acaggaactt ttttccaagt ttgaaacgca gcatcggcag ctttaactgc ttcggctgtc
    18361 tctgctttgc tagacaacgg tacattcgcc agcgcttctt ctgtagccgg attcattact
    18421 tcttcaaact ctgttgagcg actagcgacc caacgaccat caatataatt tcttaaaaat
    18481 cttgtcattt a
//
LOCUS       DACCVZ010000056        18444 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.056, whole genome shotgun sequence.
ACCESSION   DACCVZ010000056 DACCVZ010000000
VERSION     DACCVZ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.056"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..1050
                     /locus_tag="IVW63_001920"
     CDS             <1..1050
                     /locus_tag="IVW63_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAP7860190.1"
                     /translation="FLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMT
                     TGAVVSGAFLGNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILG
                     HNSHSADLASINEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALV
                     LSFIHEKSLTVGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGG
                     LLIKYLIVDTIVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSF
                     DDVGLSKTYLTRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVF
                     TILGGFLLNRRRVKN"
     gene            complement(1331..2350)
                     /locus_tag="IVW63_001921"
     CDS             complement(1331..2350)
                     /locus_tag="IVW63_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7860191.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(2372..3379)
                     /locus_tag="IVW63_001922"
     CDS             complement(2372..3379)
                     /locus_tag="IVW63_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP7860192.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(3372..4037)
                     /gene="pgmB"
                     /locus_tag="IVW63_001923"
     CDS             complement(3372..4037)
                     /gene="pgmB"
                     /locus_tag="IVW63_001923"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAP7860193.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(4030..6324)
                     /locus_tag="IVW63_001924"
     CDS             complement(4030..6324)
                     /locus_tag="IVW63_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAP7860194.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            6584..8749
                     /locus_tag="IVW63_001925"
     CDS             6584..8749
                     /locus_tag="IVW63_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7860195.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            9053..9886
                     /locus_tag="IVW63_001926"
     CDS             9053..9886
                     /locus_tag="IVW63_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAP7860196.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(9988..11688)
                     /locus_tag="IVW63_001927"
     CDS             complement(9988..11688)
                     /locus_tag="IVW63_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860197.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            12195..13355
                     /locus_tag="IVW63_001928"
     CDS             12195..13355
                     /locus_tag="IVW63_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP7860198.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            13371..13814
                     /locus_tag="IVW63_001929"
     CDS             13371..13814
                     /locus_tag="IVW63_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7860199.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(14297..14827)
                     /locus_tag="IVW63_001930"
     CDS             complement(14297..14827)
                     /locus_tag="IVW63_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HAP7860200.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            14932..15483
                     /locus_tag="IVW63_001931"
     CDS             14932..15483
                     /locus_tag="IVW63_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP7860201.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(15636..16109)
                     /locus_tag="IVW63_001932"
     CDS             complement(15636..16109)
                     /locus_tag="IVW63_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP7860202.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            16247..17719
                     /locus_tag="IVW63_001933"
     CDS             16247..17719
                     /locus_tag="IVW63_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP7860203.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            17716..18426
                     /locus_tag="IVW63_001934"
     CDS             17716..18426
                     /locus_tag="IVW63_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HAP7860204.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
BASE COUNT         5672 a         3333 c         3809 g         5630 t
ORIGIN      
        1 tttttaccga cagcatttct tgtttgtgca attgtcggag tgactgtcgg cagttcattt
       61 acaacgattt cgacgattgg aattgctttt ttggggatcg gtcatttact tggattcaat
      121 gatgcaatga ctacaggcgc agtcgtttcc ggtgcctttt tagggaataa ctgctcgcct
      181 ttatcagata cgaccaactt ggcagcgggt attggaggag ttaatctatt cgaacatatc
      241 gctggtatgc gttatacgga tttcccagca ttcgtccttt cgttgatttt ttatacgata
      301 ttaggacata acagtcattc agccgatcta gctagtatca atgaaatgat ccaaaacatg
      361 aaagcgagct tttggatctc tccttggaca ttgattccac tagttatttt atttgggggg
      421 gcaatcaaaa aaattccggc tatccctaca ttactagcgg gatcgacagc tgctctcgtt
      481 ctttctttta tccatgagaa aagtttgacg gtcggaaaag cagcagacat cttgatgaat
      541 ggttatgtcg caaatacacc tgatccaaag ctagatgaac tgctttctcg aggcgggatc
      601 atgagtatgt taggttctgc tagtttgatt ttacttgcat tggcattagg tgggttactg
      661 atcaaatatc tgatcgttga taccatcgtt caagaattaa aagaaaagat ggaccgacct
      721 tctcgtttag tcgggtttac tgccttgagc tgtatcggaa tcaatctgat cgttggagaa
      781 cagtatctgt ccatcattct tccaggagaa acattcaagc gttcttttga tgacgttggc
      841 ttatcaaaaa cctatttgac acgaacacta gcggattcag gtgcgaccgt caattctctc
      901 gtaccgtggg gagtcagcgg cacattcatt atgggaacga tgaaagttag cgcgttgcat
      961 tacttgccat tcgccttttt ctcgattctt gcacctgtct ttacaatatt aggcggtttt
     1021 ttattgaatc gtcgacgtgt aaaaaattga aggaaggaaa aaagaggctg ggacagaagc
     1081 gtttaactcc aagaaataag aagaaactca agaaaattgc tttttaaatt tttgtgaatt
     1141 tcagcttatt tccgaaggag ttgcttctgc ttccgccgtt tatacgtgtt tagagcgtga
     1201 gacaaaagtg ttctttactt ttgtcccacg ctctttttta cagataaaca atgtgttaga
     1261 agtagtatct tcttttacat aaaaagctga ccataggata aatggtcagc gtatttagtg
     1321 agtcagctat ttagtatggg ttttctaaag gaacgactgt ctctcttttg atcaagcgat
     1381 gagggatgac caaacgtacg ccactgctca attcttcatg gatcaattcg cgcagctttt
     1441 gcatagcgac acgtcctaat tcggagatat cgatatcgat acttgtaagg taagggtgtg
     1501 ttaatgttga gaagatcgag ttgttgaagc taatgacgga gagtgtctct ggaatgacat
     1561 agccatacat ttgcgccaac tgcatcgtgc gaagggcgaa gatatcgtca atgaccacca
     1621 atgctgtggc ttcgttttct ttcaacgttt tctcaaagga cagataatcc tccggatgct
     1681 ctagtactac actggataac gcaggaagac cagccatcat cattgctttt tgataaccga
     1741 aatatcgttc gaaatacaaa ctttcatgag tcgtgtttgt cacaaacagg atattcttat
     1801 gtccattctg gatcaaaaat tctgttgctt gtttacctag aagctggtta tcattatcta
     1861 cataaacgat ttcgttctca tgatgataag gctgtccgat caaagtgaaa gggatgtggt
     1921 tttggtataa ataatcaatg acagtatctt gactatctga atacactaga ataaaaccat
     1981 ctacttgttt ttgtaaatgc atacgctgga cgttctctaa cagcaattca aaatttttag
     2041 cagtagcgat tgctgtagtc atatcataat tccgcgcttc ttcgttgatt gcttccatga
     2101 tctcaagata aaatgggtta ccgatccgct cttttgaatc aagagggggt aagattacgc
     2161 cgatggcact ggaaatgcgt tttcctagat tgcgggcagt catgttagga acataaccta
     2221 gttcatccat aatttttcgg actttcttct ttgttgtctc ggaaatacta ggatgatcgt
     2281 tgatgacacg agagacggtc gaggtggcaa caccggcttt tttcgccaca tcttttacgg
     2341 taatagccat gataaaaaca cctttctctt gttattgtgc agagaaccga taaatcgtct
     2401 gactgatccg ttcttgacca ggatggaggt tgatcgatcc aaatttgggg aaatgaacga
     2461 tatcagggat ttcttgcggt tcgattgcta atccgtagtt tgaatgcatc tgttttccat
     2521 tgacagagaa atcagcttcg aatccagtcg tagaaaataa taccatactt ttattagaag
     2581 ttgctatagt catttggcga ccagaatgct tctcgaataa ttgtaaggaa gttttggaaa
     2641 gcctaggatg atgcaaaaga aatacatcat ctagtccatc tggataacat gcaaggatct
     2701 cttgcagtgt tggggatttt ctaaagtcga ttggcagttt ttcttttttt gtccaatttc
     2761 cagtaggcag tttttcttga tctaattcaa gcacaccatc taaaaagacc gttaactgat
     2821 gttcatagat gtctcttgtt ccatttcctg aaaggttgaa gtaggcatgg ttggtcggat
     2881 tgcagatggt ttcaacaagg ctactagcag aggttgtcat ctctaattcg ttttttgtta
     2941 aacggtaagt gatcgtagca gtgattggtc ctggataggt agaaaattca tcttttaagt
     3001 aaaagaccac acctattgat gatggagttt tgaaaacttc tacttcccaa aattggaaag
     3061 accagccttt cgtgccaccg tggatatggt gtgatccgca gtttttctcc aatctatgct
     3121 caccccaaga agcatcccgg atccttccgg ctacaggtcc gacagttgct ccaaaaaagc
     3181 ttttgtctgt tagaacatct tcgaaacgat cgtaagacaa taaaacattt tctgattttc
     3241 cttctttgtc tggtgcgaag atttggtgca ggcgggcacc gtaattgaga agaacgactt
     3301 ctaagtagtc gttcttcaat gtgattttct ttatttcagt ctctggaact ggtacgacgg
     3361 agatctctgg attatccatg gtcatgccac ttttctttca agtaatcgat cgtaagaaaa
     3421 gtcgtatcag ggacaagcgg gatctcctct ccaaggtctt cagcacgtcc cacgccaatt
     3481 ggttgagcgc cacttgagag gatggcttgg ataccggctt gcgcgtcttc gatcccgata
     3541 cattcttctg cttttagtcc gacagctttt gctgcaagga ggaagatatc tggcgcaggt
     3601 tttccgtttg ttgcttctgc cgggtcggca atagcatcaa agtaaggtgt aagacccatt
     3661 ttttcaagta ggaatggccc gtttttactt gcagaagcaa gagcaatctt gattttttct
     3721 tcttttaaag aatccagtaa aggcacgacc ccggggaaga catcttttgg ttcgatcgtc
     3781 tggatcatct ctaaataata atcgtttttt cttttcgcta attctgcaaa ttcttccttt
     3841 gaaaaagagt gttcttttcc gccataagct aaaagcaaag agagtgagtc ttctcggctg
     3901 acgcctttta gctgttcgtt gaatgtgtgg tcgatcgtaa tgccgatttc ctgaccaagc
     3961 tttcgccaag cacgataatg gaattcagca gtatcggtaa tgacaccgtc taaatcaaac
     4021 aatacccctt taaacatttg cttcctcctt tcttagcgtt atttctagac gatccgctaa
     4081 agaataagac tgttcataga cgtaaatttc tagaggagaa ccttctaata actcgaaagt
     4141 aacttgttca tctgtgactg agatgaacaa taaacgtccg cgataattga tatggaaaga
     4201 ataagctttc caagtttttg gcagaaatgg tgcgaatctc aactgatcat gggcagtttt
     4261 catttgagca aatccttgga caatcgacaa ccagctacca gtcatggaag tgatgtgcaa
     4321 gccgtcttct gtgtcgttat tgtaattatc caaatccaag cgagctgttc gctggtacat
     4381 ttctacagct ttgctttcca ttcctaattc tgctgctaaa atcgaatgga tacttggcga
     4441 aagggaagac tcatggacag tcattggttc atagaaatca aagttttttt gcttttcttc
     4501 ttttgtaaaa gtatcattga agaaataaat cccctgtagt acatctgcct gcttgatgaa
     4561 gcaagatcta aggattttgt cccaagacca atgctgattc agaggaagat cgcttgtggg
     4621 aatatcggat acaggcatga gatctttatc taagaatgtg tcatgctgga caaagattcc
     4681 taattcttcg tcaactggga agtacatgtt ctctgcgata tctttccatt tggctagttc
     4741 ttcttcgctg atagtgatag cagcttcttt ttgataagtt aaataatttt ctcgcgtgta
     4801 acgcaagacc caagctgcga tcgtatttgt ataccaattg ttattgatat tgttctcata
     4861 ttcgtttggg ccggtcacac cgtggatcat gtatttattt gctcgttttg aaaaatggac
     4921 acggtctgcc cagaagcgtg cgatttctgc taaaacttcc agtccttcat ttttcaaata
     4981 ttccgtatcg ccggtgtaat tcgtataatt gtagattgca taggcaatcg cgccatttcg
     5041 gtgaatctcc tcgaatgtga tttcccactc gttatggcat tcgacaccag tgaaggtgac
     5101 cataggataa agcgcgcctt ttaatccttg ttgctgagcg ttgtggattg cttgcggcag
     5161 ttgattatgc cgatatttca gcagattctt agttacttca ggtttggcta aagcaagata
     5221 aagagggaca gcatacgctt ctgtatccca gtaagtggct ccgccgtatt tttctcctgt
     5281 gaatcctttg gggccgatat tcaatcgttc atcttcgccg tagtaagtag agaatagttg
     5341 gaacaaattg aatcgaatac cttgttgtgc ttcttcgtct ccttcgatga ccacatcggc
     5401 aagcttccat cgttctgccc aagccgctgt ttgctcttct tttgcttgga tataattgtt
     5461 tgtctggttc gttaattctg agacagcttt ttctgcttgc tgcgcttctg gaatatctct
     5521 actagtaaga acgataattt ctttttccac tgaccatgtc tcaccttgag ataattctgc
     5581 agacaagcaa ccatgtaatg ctaaagtatc ttcgtgatag tcagggatga ctgattttcc
     5641 attaacgaaa tggcgcattg ctgcagtaac agtaaattgt tcaatcccaa agttgtttgg
     5701 aatagtttta gtcgtcaaat agccgatttc ttctatagtt ccacgatcaa tctcattcca
     5761 aaaatgttca tcatagttgc tgtcttcgtt ttgaacattt ccatccaatt ttgatacgag
     5821 tttgactgtt ccgctacctt caagcatttc tatagttaaa tagatataag ctgattcttt
     5881 tttgacaatg ctcagaaaac gttcgaagga aatgcgtact ttattagtag aagtagtgat
     5941 tgtgaatgta cgagataata caccattttt catatctaat tcccagtaaa agtcttctgg
     6001 ttccaaagaa gccaagtcga tcagctgatc gttgatcgaa atatctatcg cgataaagtt
     6061 caaggcgttg atcacttttc caaagtattc tggataacca tttttccacc agccgacacg
     6121 tgtcttatcg ggataccaga cacccgccaa ataagtacct tgatggtggt cccctgagta
     6181 agtttcttca aagttcccgc gcatccccat ataaccgttt ccaatacttg ttaaagattc
     6241 ttgcagtcga agattttttt tatctaattg tgtcgtgctg attttccatg gatcaatagc
     6301 aaatagtcgt ttgatctgtt tcatttttct cctcctaatg agctgtttta tacgttcata
     6361 ataaacgcaa ccgattgcac aagtcaatag acaaaagaaa atatttcata gaaaaaagct
     6421 taaaaaaata aatttttagg agaaaattat agaagggaac acacgtatta taggttttat
     6481 agaatggtat agacagaaaa ataaaaaata aagcatttac aaaaaagaaa acgcacgcta
     6541 taatacgttt aacgaaaccg attgcgtaaa ggagctaaac ggaatgaaaa agatatttag
     6601 ttttgagttt tggcaaaaat ttggaaaggc tttaatggtt gtggtagcag ttatgccggc
     6661 agctgggttg atgatcagta tagggaaatc aattcccttg atcaatcctg attggacgcc
     6721 gcttgtcaca acgggcggag taattgaaaa tattggttgg gcaattattg gtaatcttca
     6781 tattttattt gctttagcaa taggaggaag ttgggcaaaa gaaagagcag gcggagcatt
     6841 tgcagctggg atctcattta ttttaatcaa tcggatcact ggggctatct ttggtgtcac
     6901 aagtgacatg cttgcgaatg aagatgcatt tacccacact ctgttcggta cgaagatcat
     6961 ggttaaagga ttttttacaa gtgtattgga agcaccagct ttgaatatgg gagtattcgt
     7021 agggatcatc gctggatttg tcggggcaat ggcttataat aagtactata attatagaaa
     7081 attgccggat gctttgtcat ttttcaatgg aaagcgcttt gttccgtttg ttgttatctt
     7141 atggtcaaca atcgtggcat tgattcttgc tgtggtgtgg ccaaacgtac aggctggaat
     7201 caataatttt ggtttatgga ttgcagaatc acaagaaagc gcaccgattc tagcaccgtt
     7261 tttatttgga acattagaac gtttactatt gccatttgga ttgcatcata tgctgacgat
     7321 tcctatcaac tatacacagc ttggcggatc gtatgagatt ttatcaggcg cacaggcggg
     7381 gacacaagta tttgggcaag atccgttatg gttggcttgg gccactgatt tagtgaatct
     7441 taaaggtgca ggggatatgt cgcaatatga gtttgtgttg cataactgga cgccggctcg
     7501 tttcaaagta ggacaaatga ttggttcttc aggtatcttg atgggaatgg cttttgcgat
     7561 gtatcgtaat gtcgatcctg ataagaaagc aagatataaa tcaatgtatt tttcagcagc
     7621 gttggctgtc tttctaacag gtgtaacaga accattggag ttcatgttta tgtttgctgc
     7681 tgtgccatta tatgtcattt attcagtgat ccaaggggct gcatttgcga tggcagatat
     7741 cttgccattg cgggtccatt catttgggaa tatcgaattg ctgactcgga caccgttagc
     7801 tatcaaagcg ggtctaggtg gagatcttat caacttcgtg ttgtgtgtga tcgcttttgg
     7861 tgttgttacg tatttcttag caaatttctt gatcaaaaaa ttcaactttg ctacaccggg
     7921 acgtaacgga aattacgaca atgacagtga agaaaccgtt gtatctaaca gcggaacagg
     7981 aacagcagat cagcaagtgg tccagatcat tcatttgctg ggaggaaaag aaaatatcaa
     8041 agatgtcgat gcttgtatga ctcggttacg cgtaagtgta aatgatcgag aaaaagtagg
     8101 gactgaagaa gcctggaaac gagcaggggc gatgggattg atcgtcaaag acaatggagt
     8161 ccaagcagtt tatggaccaa aagcagatgt cttgaaatca gatatcgaag atctgctgca
     8221 atcaggagca gagattccag agccagaaat ggtttctaca ggaaatggac aagcaggtag
     8281 taagcaatac ttaggtatag aacaagaact agtttccgca gcttctggag aagtgattcc
     8341 tttatctgaa gtaaaagatc cggtattctc acaaaaaatg atgggtgacg gctttgctgt
     8401 tattccaaca tcaagagaag ttgttgcgcc gatcgctgga aaagtgacaa gtattttccc
     8461 tagcaaacat gcaattgggc tggaaacgaa agatggtatc gaagttttga tccatatggg
     8521 aatcgataca gtccaaatga atcagccagc ttttgagatt gctgtcaaag aaggccaaga
     8581 agtaggaaca ggaacgaaat tagctgagat ggatcttgat gtgatccaaa acgaagaaaa
     8641 agatccaacg atcatgatcg tatttacaaa cgataaagta gaagaagtag tgatcaagca
     8701 attaggtaca gtgacagctg gtaaagtgat cggctccatt aaaatgtaag gagaggttgt
     8761 gaaaaagctg tcctgcatca agtcataaga acagccaaac aaaaatagct cctcctattt
     8821 ttcgtttggt tgggcttatt accgagaagc agcagtttga atactgttta gtggagaggt
     8881 cgtgaaaaag ctgccctgca ccaagtgata aaaacagcca aacaaaaaat agctcctggt
     8941 ccattgagct tattactgag gagttagcag gagaacacta tttgctggag aggttgtgac
     9001 aaaaattttg tcacaaccct tttgtttcga aatgaagaca aggagaaaac caatgaaatt
     9061 catgacactc aacacgcata gctggcttga gccagaacca gagaaaaaat tgcaagaatt
     9121 agcagataag atcctgttag aagattatga agtgattgct ttacaagaaa tcaaccaatt
     9181 actggaatct gaagaagtag aacctgcgaa gctaatgaag ttctgtccgg taaagaatca
     9241 agtacctatc cgtaaagata attttgccta ccgtttagtt cagcttttaa aggaacacgg
     9301 aaaagagtat ttttggagtt gggaaatgag ccacatcggt tatgataaat atgaagaagg
     9361 aaatgcactg cttacgaaaa aaacattgga aagtcaggtc cttaccgtct cccaatttca
     9421 aaagaaagaa gattatcaga cacgcaagat cttgattggg aaaacaaaga tagatgatca
     9481 ggacattttt gtctcgagct gccacttttc ttggtggaca gataaaaaaa gtggctttta
     9541 ttttgagtgg aaaaacttgg aaaactactt tttggaaact cgcgtaccac tttttttcct
     9601 aggtgatttc aataatccag tagactctca aggttattat actgtaagag aaagttgcct
     9661 tcttcttcaa gattcgtatg ttgtcgcgaa tgaaaaagga aaagcagcta ctgtggaaaa
     9721 gaaaatagat ggttgggaac aaaatacaga aaaattgcgt atagatttta ttttcgtccc
     9781 tgaaggaatg caggttaaaa aatatcaacg gatttttgat gggatcgata gtccaatcat
     9841 cagtgatcac tacggggtgg aaatcgaatt agatgtgaac gaataaaaaa tataacatat
     9901 aacataaaaa aactgattaa aataaaactc tccaaacgat tataccgttt ggagagtttt
     9961 ttgatcggat gtatttatcc cttttgccta agcacgtaaa agcttgtatc tatgataaat
    10021 aaataaacat agcaaggtaa accagccaat caaagtaaga gaaagaatga aatagaaata
    10081 gattggcgtt tgataatgaa gcgtgagctc gttgattcct ttttgctgct tcacgattgg
    10141 ggtcccgata tctgttactt cataatcagt caatgttttt ccattttgct gtagcacagt
    10201 ccgatcgtag acgataacag ggatatgaac agttttgtcc ccagtgtttt tccacttgat
    10261 tgtcaaaaga ccgcctggat gtgtttttat aaaagttgtt tcgttttcta gtatttcttc
    10321 gttataccgg tcgtatttat tgtcttttgt ctccttatag attggcagat agtcaggtgt
    10381 ggttttttgg aaaacgaaca agctggtaga catatctttg ctgaagaatg ttttccttgc
    10441 ttcttccggc gtatcgaata gataagtatg tcgactgaca aatgtttcat tttcccactt
    10501 ttccagatgc tggtataagt tctggatcgt ctgtgctgaa aaaataagaa tgccaaatat
    10561 acttaaaaga cggaaccact tttgttcaga ccactggttc agtgaaaggg caaggtaaag
    10621 tagaagcaat agcgtaaatg gcacgaaaaa tcgaaatgga aactggatca aactaataaa
    10681 aggcacattt ttttcgatca atgtcgtcca tggaatcaag ctagtagaaa gaaaaaagaa
    10741 aacaagactt gtgtacaaca cgattttttg gaataaggtg ttcttttgtt gaaagaaaat
    10801 aaaaagcaaa aaacctgata atatcaatat aggaaaggcc ttagggtaat ggagccaata
    10861 actgccatcc agatctatcg ccttttgact catttctctg ttaacaaagg gaggaagaat
    10921 cttattccca ctgtaaacaa tagctaatcc tgcccaaata tttgctgtca gaacaaaata
    10981 aagcaagacc gacttaatca gttgaagcag tgcttttcct ttttcagtct ggttaaaaaa
    11041 gtaataaaga taaaaaggga tatacatcaa agctaacatg atcgaagaca gtaaatggat
    11101 ctgtgtcata agtcccactg agacagcgac tttgataaca gggaactttt tatgaaggac
    11161 gaaatcagca atagggatca tacataaagg ataaaaacaa gtcccccagc tagtgaatcc
    11221 ttggttgata gaccagtatt gaatagaata cgtactcatg aataaaacgg ctactggtac
    11281 acttacccaa tttcgaacat tgacatatct cagtaaaatc agcatagaaa atcctgaaat
    11341 aagataaaga atgaaatttg aaagaatctg ataatgaaac cagctacctg caagcaacac
    11401 gatcaatcct tgtaaataag cgaaaaatgg gccgtaaacg gcattcacga tcctgccact
    11461 ttgctggaat ccataaaggg aaggaaaata atggaaatcc ccatatttaa tttgttgcgc
    11521 ggcatcatag aaccgattgt aatggaatgg ggcatcagca cccaaaatta gtttatgtgt
    11581 gaataaatga ggcatgagaa atgccaaagc aatgaaaaaa attgctaaaa atgggccata
    11641 ttttttcaat tgtcgaactc ctttgcaaac tttagataaa ttcatcatat atcctatgcg
    11701 agaggtaggc aagaaattag aaaattcatg aaaatattta tgaattttac aagaaaaaca
    11761 taagtgaaag ttctaaggag agaggatgcg acataagttt tgttgcatct ccttgttttg
    11821 aaacagaatt tttcttaata ctcgaaacaa agtagctttt tcatgacctc tcggtaaacg
    11881 gtgttcaatc agctgcttct cggtaataag ctcactagcc tagaaaatat gagaagctat
    11941 tttctgacta gcgctcttat tactcaaagc ataacgcagt tttcacaacc tcttccttaa
    12001 acggtgttca aaagcttgca tctgcggtaa taagcccaac ccaacaaaaa atatgagtag
    12061 ctattttttt gggctgtact tattacttga tgcaggacag ctttttcaca acctcatcgg
    12121 ctttcatttt ctattttttt cctgaaccca tataataaaa gaaagaacaa aaaaacttgc
    12181 aagggaggac acatgtgaag cagagtaagc aaaaacagtc tcgtcgactt ttgtttcgtt
    12241 tgtttttatt aatatgtatc gtcgtagggt tactgatcgc tttatatcca ttttatgtgg
    12301 attctttaaa tagttttatt gatcaaaaac gtatcgaaca agtacaaaaa cggaccgcag
    12361 ctgaaattga agtgcagcga aagaaaatgg aggagaaaaa ccaacgatta actgaccaag
    12421 gattcaatcc tggtactgat cctttcaatg aaaagaacag aaatgaaagt acaacatcca
    12481 gccaattaga ggaatggctg atcggaagta tcaatatacc taagatccaa ttaaatattt
    12541 cactttatga tcggctcaat ggtaggatcc ttgaaaatgg agcaggcgtc ttgcaaggaa
    12601 cctctttccc gcttggtgga aattcgacgc attcagtgat ctctgctcac agcggtttac
    12661 ctaatcgacg gttatttacc gaattagatc gtttagaaaa cggagacacg tttattttga
    12721 ctgttttggg ggagaaattg gcttatcaag ttaaaaatat acaagtggta ctgccagatg
    12781 acacgtctgt tctaacgatt tcagaaggag aagacttagt taccttgctt acatgtacgc
    12841 cgtatatgat caacacgcat cgtttgctag tgacaggaca tcggattcct tataacgaat
    12901 cggtaaaaaa agaagaagga aaaggaaatc aggaaagaac catgcggcaa tggtttattc
    12961 ttgcaggaac gataatagct gtagtcatac tgttagtgtt tatcggacga ctaatctatc
    13021 agtatagatt aagtaaaaaa gtgcttgatt tttcatttat tattagtgat tcgtcaggga
    13081 aaccggtaaa tggtagttca ttcattttga aacataagaa aaaaacactt actagaaatg
    13141 gtgtgccgtt ttcagtacaa agcgaccatc atgggaaagt caagctggat caattgcctg
    13201 gtggaactta tcgaatcgtt tcagctgatg atcctaaagt tgctgtttct tttggtatta
    13261 gaaaagtaaa acaagagaag atatactttt ttgaggggcg aaaacttgta aaagagcttc
    13321 aaaaaaatgg tttttatttt aaaatcaatg aataagtaag gagagaaaaa atgatccgca
    13381 caacaacaaa attgtctgcc aaagaactgg aatctgttct atcgatttgg ctgcatgcta
    13441 acttggattc tcatgaattc attccatcaa cttattggga gaatcaagta gaatctgtta
    13501 ggaaagcttt accagatgca gtgatttact tagcagaaat agatcaagaa attattggtt
    13561 ttgctggggt gattgatcag tttatcgcag gaatctttgt gaaaagggaa taccggcaac
    13621 aaagaatcgg tacgcaacta atgaaaaaaa taaaagaaac caataaaaca ctgactttga
    13681 cagtctatca aaaaaatcaa tcagctattc atttctatct ttcacaaggt tttacaattc
    13741 aaacacagca aaaagatgaa gcagtaaatg aggaggaact tgtgatgaaa tggaatcaaa
    13801 acgctgattt ttgatgaaca gaataacgaa ataatgctcc cagcctaatt ttttgctggg
    13861 agcattattt cattttgaag tcactaattt aactgtgtga atatgcagtt gttacaatct
    13921 ttgataaacg gtgttcaatc agctgaccct cggtattagc tcaaaaaacg gcaaaatatg
    13981 aggaactatt tttccatttg tttctctaat actcaggtca aaacgctgat ttcacaacct
    14041 cttgataaac ggtgttcaaa cggctgcttc tcggtaataa gcccactagc ctagaaaata
    14101 tgaaaagcta ttttctaact agcgttctta ttactcaaag cataacgctg atttcacaac
    14161 ctcttgataa acggtgttca atcagctgac cctcggtatt agctcaaaaa acggcaaaac
    14221 atgaggaact atttttccgt ttctttctct aatactcagg tcagaacgct gatttcacaa
    14281 cctctctttc acaaccttat tttactcgtt tataattttc atcgaagtat tttccgctac
    14341 ggatatcatc tggcattcca tcgtatggtt cttcgctaat aacatcttca ttgtctatac
    14401 ctgcatcacc catataagtg atcgtagcaa attcaggaac aagtaatttt ggataagttt
    14461 catatttttc acgagctgct tccatttctg cgatatgttc gttttggaaa gtaacagtga
    14521 tttctggatg ttcttcaacc catttaggga aaaagatcat tccgtgaagt ttcttttcat
    14581 ttggcataaa gtccaatgcc acgtctgtcc ctgttggctc tgtccaagtg attttgaata
    14641 cgccgtccgt caatttaacg atatcagctt cttggtcttt tacccaacgg cctttgacca
    14701 ttccgccatg gatacggtaa tcaacagtat ggtcattttt ggcataccat tcatattccc
    14761 aaccattgtc atacgtatag ataaagtgag ttccaataaa atcttccaat tctttaaatt
    14821 ctttcatgtt taagcatctc cttataaatt aaaacatgta ataaactaca tgttttcgat
    14881 tactcattta tgatagaatg gatttaaaga tttgtcaagg agggaaaact gatggcaaga
    14941 aaaaatacac ttcgatatat tttgttaggg ttattaagta agaagaagat gacaggatat
    15001 gaattgaatc aatcgttcaa aaatgaaata ggagaatttt ggcaagcaaa acatagtcag
    15061 atttatcctg aacttgcaaa aatggaagag caaggaatca ttcagcatca agtagagatc
    15121 acaggtgaaa aattggaaaa gaaagtttat gaattaacag aagaagggaa ggaacaattg
    15181 gcagagtgga ttcatacacc caccaatgaa ctaccggtta atcgagacga atttgttctg
    15241 aaattgtatt tcgtcaaaga cgtgaatgat ccggcattag tagaaattat tcagcagcag
    15301 cgtgaccttc atgaagaaaa acgacttcat ctattagagc gaaaaaaaac gatctttcct
    15361 actgaaaaag aaaaacatga aaattacgga cactacctga ttttagcgca tgcgatcaat
    15421 cgggaaacag aatatgcaaa ttggctaaca gatgtattag aagaaagtaa ccgaaaaaaa
    15481 taaaaaaata tccgaacagt gatggagaat tcctttctat atgaaagaaa cgcagatcac
    15541 cgttcggata ttcttatgtt caaacaggcc ttttttcaag tatttatgta gcatctactt
    15601 attaaaaagc ttggtactta ggagattagt ggcgtttaga gttcttttaa caactgttcg
    15661 tagtcagctt tttcatcgac aggaaggagc ttgtaagtta attcgtctgt ctcgttgtca
    15721 tgaatgatgt acatcttagc attctcttct ttgaagttac cgatttgtaa aatcgtatag
    15781 cgttcgtcga tcaattcgat atctttgatt gcttttgaaa aaactttacg gacatggtgc
    15841 attttctttt ggcggatttc tgccttttct gcagcttttg acaaagtaaa tccgtcatct
    15901 aaatattttt tgatcagttc tacttttatg actgtaggta aacgatattt tctaggacaa
    15961 ttcgcatcag cttcgatcga acgaatgaat cccttttgtt cccaatacct taattgacgt
    16021 ggagacacac ctacgatatc acttaattca ctgatgccaa caaccaattg atcattttcc
    16081 aacaaacgtt taagggaagc cccaaccatt tttgtcactc cttttgtcct cttgcttccc
    16141 ttaattatat ccgtattaac ttatgtgtca agtaggttga caaatagcga atttaggact
    16201 aaagtattct agtagtttca gaaaaaattc agaaagaagg agaaatatga gtaacaacca
    16261 acccgtagat atttacggaa aaccatataa tcggacactt ttagttgttg tcttattaat
    16321 tggtacattt tgtaccgttt tgaatcagac cttattgacg acagcttttc ctacattgat
    16381 gaaagctttc gatatttcag cgtctgatgt gcaatggtta acgactggtt tcttgctagt
    16441 caacgggatc atgatcccaa taacagcatg gctgatcaat aaattcagtt caagaaattt
    16501 atatctttct gccatgacga tctttttgat cggaacgatt acttgcttta cagcacctaa
    16561 ttttagtaca ttactaatcg gtcgtttgat ccaagcttgc ggtgtgggag tatcgatgcc
    16621 attattgcaa aatatcatgc tatctatttt cccgccagaa aaaagaggat cagcaatggg
    16681 gatgtcaggg atcgttattg gacttgctcc tgctttaggc cctacattat ctggttatat
    16741 cattgataac taccattggc gtgacttgtt tggtatggta ctgccaatcg ttgttcttgt
    16801 cttggtttta gcattcttcc taatgaaaag tgttattcca ttgtcaaatc ctagcattga
    16861 tattttatcc gctattttat caacgattgg attcggtagt ttactttacg gattttctag
    16921 tgtaggagat gacggctggg gaagcttgaa agtaattggt ttcttagttg ttggtgtgat
    16981 tttcatcgcc ttgttctcat ggcgtcaatt acatttggaa catccattct tggaacttcg
    17041 tgtattcaaa tcatctacat tcacgattgc agctgtttta gctggtgtaa caaatatggc
    17101 gatggtaggg gcagaaatgg tcgtaccatt gtatattcaa aatattcgtg gagaatcagc
    17161 attccattct ggcttgatgt tgttgccggg tgcattgatc atgggggcta tgatgcctgt
    17221 gacgggtgcg attttcgata aatacggcgc gaaacgttta gccatcacag ggatgttcat
    17281 tttgacagcg gcaactgcac catttgcttt cttgacaaaa acgactccag ttttatatat
    17341 cgtgatcctt tatgcgatcc gtatgtttgg gatctccatg gtcatgatgc cggtaacgac
    17401 ttctggtatg aatgcattgc caaataactt gatcagtcat gggacagcgg taaataatac
    17461 attccgtcaa atcgcaagct cgattggtac agctattttg atcagtgtgt tgacgaatgt
    17521 gacaaaagca aatatcccaa gcaaatctgt attggataat acgccattag cttataaaga
    17581 tcaggcaatc aatgccacac tgtcaggtta ccatgccgcg tttatcgtag cgatcatctt
    17641 tgggattctt ggctttatta ttgccttttt attgaagaaa aaagaacctg ttctaatgaa
    17701 agcgggggat aatgcatgat tattggagtt ttgattgtca gcttgcttgc ttttgcttta
    17761 acgaacgtgt tcgctaaaaa aacatggcaa acctttttat ctttgatttt cggactaatc
    17821 ttcgtcgctt cactaagttt gatcgtcgct aatttgtcca atcactttgg aatggaaaaa
    17881 gtaacggaaa caaaaacaga aaaaattgtt tccagtgctg attcccaagg agcagatatg
    17941 cttttgtata aagctttagg gaatggaaaa gaaaaagtgt atctttaccg aacaaatgaa
    18001 aaacaagaaa aaccaaaagc aactggtacg gataacgaaa caaataaagt agaaaagaca
    18061 gacggcgatg ctgaaaaagt gacgaaaact acttattggg aatacaaaaa cgacatgtat
    18121 aaattctggt tcaatattgc tgataacaat cacgaatatg acagccgagt gaatacattc
    18181 aaaatcccag agacatgggt agaattaagt acggaccaag cagccaagtt agctgaatta
    18241 gtgaagaaac agcaaagtac gatggaaagt gaagcaaaag cttatgttca agacggtatg
    18301 gtaaaagcaa tgactgaaaa tccaaaaatg agcaaagcag agcaagaaca acgtacgaaa
    18361 gccttagctg ctgaattcca acaacaagca ttcgcaaaat tagtgaaaga agcaaaaggc
    18421 gaataatatt ttgaacacca tgta
//
LOCUS       DACCVZ010000057        18230 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.057, whole genome shotgun sequence.
ACCESSION   DACCVZ010000057 DACCVZ010000000
VERSION     DACCVZ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.057"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(49..873)
                     /locus_tag="IVW63_001935"
     CDS             complement(49..873)
                     /locus_tag="IVW63_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP7860205.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(846..1526)
                     /locus_tag="IVW63_001936"
     CDS             complement(846..1526)
                     /locus_tag="IVW63_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP7860206.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(1549..2487)
                     /locus_tag="IVW63_001937"
     CDS             complement(1549..2487)
                     /locus_tag="IVW63_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HAP7860207.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(2732..3583)
                     /locus_tag="IVW63_001938"
     CDS             complement(2732..3583)
                     /locus_tag="IVW63_001938"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAP7860208.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(3737..6310)
                     /gene="mprF"
                     /locus_tag="IVW63_001939"
     CDS             complement(3737..6310)
                     /gene="mprF"
                     /locus_tag="IVW63_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAP7860209.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            6451..7257
                     /gene="proC"
                     /locus_tag="IVW63_001940"
     CDS             6451..7257
                     /gene="proC"
                     /locus_tag="IVW63_001940"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAP7860210.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(7336..8892)
                     /gene="rny"
                     /locus_tag="IVW63_001941"
     CDS             complement(7336..8892)
                     /gene="rny"
                     /locus_tag="IVW63_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAP7860211.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(9303..10352)
                     /gene="recA"
                     /locus_tag="IVW63_001942"
     CDS             complement(9303..10352)
                     /gene="recA"
                     /locus_tag="IVW63_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAP7860212.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(10461..11702)
                     /locus_tag="IVW63_001943"
     CDS             complement(10461..11702)
                     /locus_tag="IVW63_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAP7860213.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(11942..12520)
                     /gene="pgsA"
                     /locus_tag="IVW63_001944"
     CDS             complement(11942..12520)
                     /gene="pgsA"
                     /locus_tag="IVW63_001944"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAP7860214.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(12729..13613)
                     /locus_tag="IVW63_001945"
     CDS             complement(12729..13613)
                     /locus_tag="IVW63_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7860215.1"
                     /translation="MAFETIGEKLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFD
                     QLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQPETVSTSRKAMHQ
                     EESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDTASSLKVEGSVEES
                     SSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITDATKPVTLEFTAVN
                     RVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNATIKANGESVPVNP
                     GENNQSPKNVNLTLQYAE"
     gene            complement(14390..15676)
                     /locus_tag="IVW63_001946"
     CDS             complement(14390..15676)
                     /locus_tag="IVW63_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAP7860216.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(15669..16937)
                     /locus_tag="IVW63_001947"
     CDS             complement(15669..16937)
                     /locus_tag="IVW63_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAP7860217.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            17189..17650
                     /gene="mscL"
                     /locus_tag="IVW63_001948"
     CDS             17189..17650
                     /gene="mscL"
                     /locus_tag="IVW63_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAP7860218.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(17709..18155)
                     /locus_tag="IVW63_001949"
     CDS             complement(17709..18155)
                     /locus_tag="IVW63_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7860219.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
BASE COUNT         5201 a         3985 c         3185 g         5859 t
ORIGIN      
        1 agcctataaa aaatttttcg tttttataag gcttcttttc tttataattt agttattttt
       61 tcttctgaag gcaaccaata ttcgtttgat gatatttaca atcaggaaca aagcaataaa
      121 gactaatgtg attgttgctc ctggaggtgt atctagataa aacgagctag ttagtcctga
      181 cagcatccct agaaatccta cacaaacact gatagcaatc acgacattga agcttttgcc
      241 taatcgcata ccgattgctg cgggaagaac catgattgcg gatatcaaaa gtgcaccggc
      301 aatcgggatc atcacagcaa tagccacacc agtaatcaca ttgaacatca tcgacatcaa
      361 atgaacgggt agcccatcca cgtgggcggt atcttcatca aaagtcagaa catacatcgg
      421 ccgtttgaat aaaaagaaca atataccgat ggcaacgaat aagattccta aaaagatgac
      481 ttgctcccat gtaatggtca cgatcgaacc aaacagatag gattggatac ttgttgctga
      541 attccctccg ctcaaattca tcaatactaa cgctagcgcc aaaccaccag ccattaaaat
      601 ggcaatggag atttctgaat aggttcggta gatcgttcgc agatactcca atatcacagc
      661 tgctaataca acgactagca tggtcgtaag tgtaggatta aggttcaaaa agaatcctaa
      721 cgctacccct gctaaagaga catgagaaag cgtatcagcc atcagcgatt gtcttctgat
      781 cactaaaaac acacctagca tcggggcgat tccggcaatg aagatagcgg caagaaacgc
      841 tcttctcatg aattcatatg aaagcaacgc cattgagaat cctcctttct caccagtcgg
      901 atctgtctgt ccgcatactg tttgatatct tcatgatcat gggtgatcat tagaactgat
      961 ttcccatgga catgcgcact atgtcggaga agacgataaa attcatttct ggattcttca
     1021 tccatacctg ttgttggttc atcaagaaca aataagtcag ggtcagtagc aaaaatacgc
     1081 gctaaactga ttcgctgctt ttgtccgcca gacaattcac ctattcgccg atttcgcata
     1141 tcccacatcc ctacagcttc taaagcacgc tgtacatgtt gatgatcttt ttcagagaga
     1201 cgcttgaacc agcggcctct tggatatctt cctgaacgga ctaattcgat caccgtacta
     1261 ggaaaacctg cattgaaaga tgcaacttgt tgaggaatat aaccgatact taattttttt
     1321 ccttcttgat ttttctcagc aatctttatc attccttttg aaggtttcag taatcctaac
     1381 gatgctttca ccaaggttga cttggctgct ccattttctc cagttaaaat gacaaattca
     1441 cccgcatcta catgataaga gacatcttct agtacaggtt catcatcata gtaaaaggtc
     1501 aaatcagata tttcgatata acgcacctta caacctccat tctaaaactt aattgatact
     1561 ttcttttaaa gctttcagat ttttttccat gacagaaata taattttcgc ctgctttgat
     1621 ttgttcatta gtcaagcttt ctaaaggatt caacacttct agcttcactc ctgtttcatt
     1681 cgacaatgtc tcagctacct tcgaagaggc attttcttca aaataaatca ctttgatgtt
     1741 gtttttcttc acaaattctt ttagctcagc taagcgactt ggtgtgggtt cctgatctgg
     1801 tgaaacgccc gaaatcgcta cttgttttaa gtcgtattga ttcgctaaat aagcaaaagc
     1861 agcatgctga gtgacaaatg tgcggtttgt tgcatctttt agctcatcgg agtatttttg
     1921 atccagtgct tcaagctttt tgatataagc atcggcattc ttcgtaaaag tttccttttt
     1981 atctggatat ttttcgccta attcttcagc aatcgttctg acttctttta tagctaatac
     2041 cggatcgagc caaacatgtg gatcgtattc atgtgaatga ccatgccctt cttctgattc
     2101 ttcatgttcg tctgcttctt gcgattctaa acggtcgatt cctttagctg cttcgatcat
     2161 caaggtctgt ttgctatcca ctgaatcctt taacgaatcc acaaaaaatt ccatgtctga
     2221 actattatac acgaaaacat ctgcatcgga aatttctgct ctttcttttg cacttggttc
     2281 gaaatcatgc ggctccgttc cagcagggat caaaagtttc acgtttcctt catcccctac
     2341 gatctctttt gtaaaatcat acatcggata aaaagtcgta acgatcgtca aatcctcttt
     2401 tttgtctgct tccttgttcg tatttccaca tgctgcaaac agtaaagcac ctatcattac
     2461 cgtagctgtc aaaagatatt ttttcattta tatgctcctt tcaatgaaca aatcggaatt
     2521 ttacgattta ttaacgtgaa ctaatgtatc aaaataaaaa aacacagtca atagaaatcc
     2581 atcaatttct gatttaagca tgtatattct tgattaaatc gtaaaatgga tgagttgctg
     2641 ctcatatcta gccatttcac tacaataaaa aactgaagaa taccatttta ggattcctca
     2701 gtttttcatc acctatttta cttcttatat tttattgcag ggttcgtact aaataaactt
     2761 cctcacaaaa accttttaac ccattatata ctctctgcgc tcttgaataa tgttgacaca
     2821 aggcaaaaac ggttggtccg cttccactca tcaatgcagc atctgctccg tacttgatca
     2881 tacgctcttt gatttgatgg atgactggat gccgctttcc cgttatatct tctaaactgt
     2941 ttcccatttt tttgatcatc tgctgataat cttgctctcg gatggcttca gcaagtccgt
     3001 ggatgtcttg atgttggatg gcttgcgtat ctacttctct aaacactgta cgtgtagaga
     3061 cactcattct tggtttgacc aacacaaccc agcactgtgg catagaaggt aatacttgga
     3121 tttcttcccc tttgccaccg acaaatgccg tacttccgta gacacagtaa ggaacatctg
     3181 taccgacttc caaaccgatt tctgccagtt cttctaacga acagcccaga ttccataatt
     3241 ggttgatccc tcttagagca gctgcacagt ctgtacttcc tccgcctaat ccagctgcta
     3301 ctggaatatt cttcttaaca aagatcttga caccggtttt gatattgtat ttatttttta
     3361 gcaataaagc agcttgataa acattgttcc gttcatctac cggtaaaaat gctttatttg
     3421 tttctacaat gattttgtct tctgttattt cttcaaaaaa tagatgatct gccaagtcta
     3481 cgctcgacat caccatttcc aactcatgat acccatcttg ccgtctatat aatacatcca
     3541 gtcctaaatt tatcttggct ggcgcttttt caatcaattc catcctctca cccattcgaa
     3601 aagtctaagt cgcaagtatt ctatcatagg gaaaaataaa agtatagctt atgtctgcct
     3661 agtggttgat tttgtcatcg tttcaacagc tttcacagaa ttttctcttc ataatccaaa
     3721 caagttctag tgattcttat aattctgtga gcacttcttc tgccaaactc ggaacatttc
     3781 ctttttcttt tcctatcaga ctgagtagct gcatggtagc aaatccgaaa ttacttcctt
     3841 tcctataagc aaaataacgt ccttcccaat gatcgacata ttttaatttc ttttcataag
     3901 cagactggaa ggaatagaaa aaattaccat aattatatac gatatgcatg actttttctt
     3961 gaaagaaaga aaaatctgtt tctccaacat tagctaatgg agctaagcct agattggctt
     4021 ccgagtagcc cattttctcg tatacaataa acagattggc taacagatag tcagctaatt
     4081 cctcagattc tttaggtaag acccgcaaca aatcatatcc cgcctgcttc ttcgtcatcg
     4141 gctgagcggt gatgaagcca acgacttttt gatctttacg gacaataccg acaccgctag
     4201 ataatacata tgatttatca aatcgtccca cagagaagta tttttctcgt gcaccttgaa
     4261 gccatttttg tgaaacttca tttacagctt gatgtaattc ttccggcagt tgatcgtacc
     4321 aagtaaaatg gtatccttct ttcatcaaac gttgatattc aagttgctga ctcagccgag
     4381 acaagtcttc tgttgctaga tcaacaatcc ctgcttcacc tactttcgtg aagtgaaaac
     4441 ccaattcatg aagcatcact acgtagcttt ctgatatctt ataaaacgca agctgatagc
     4501 ctaaacaatc tgcttgtttc ataaactgat tcgttgctgc ccgcatcatt ttaggattgc
     4561 caactggatc tcctaaaaca aagcatttgt ttcctttgat ctgataacca aaaacgactt
     4621 gatcttggtc gtcttcttgg taataaaaat aactgtaacc tgacaagcga agctgatggc
     4681 ttgtagctgt gcctccgtat gtttccaata aacggtcaaa acggtctttt tcgtactcac
     4741 tgccaagctt cgtagtatct tcagctaaat attgataaag cgccactaaa gctagcaatg
     4801 agatgcccaa accaataagc cctgagaacc acacatcatc tgaaggaaac aaaataaaat
     4861 gatttcctgt tattcgaccg actaaaaagc gtccgctgtg atagcctgca attgcgtaaa
     4921 cgataaacaa aaagccgaac aagctagcat caaagattat agctccccaa gaataaacga
     4981 attttgttcg ataaaattct tttctggata accacacagc taacagaatc aagacatata
     5041 ccaatatcaa ctgccaagat aacgtacgtg tgattgtatt taaaatacca aaagatagta
     5101 aagcaatcgt aggcagaaat gcctttttga cttttactga aagtgctcta gcaaggccga
     5161 gtaataaaaa gccaaccaat agattcactg tctgatctaa aaaattgaat gagaacggca
     5221 ataatacttg aaatagccga ctgattgcag acagattagt gattgttgat agaagtacca
     5281 tcatgatccc cgcaaaatag acagcactta cgagcacgat atgcgcaacc ttttggaaaa
     5341 acagtcgcgg aatgttatct aaaaatcgat tgattttgac tcctgtatgt gtgatgaaca
     5401 atagaagtcc cgtcataaaa ggtagaacat aataaaacaa ccgataatat aatagccaaa
     5461 ctactgctac atcttgccga acaggcaatt gactcattcc taagatcatc aaaacgtcaa
     5521 aagtccccat tccacctggg accatcgtca gcattcctat caatgtagca atcatgaaca
     5581 taggatagat cgaaagcatc gaaatatcta ttctcatcaa cttgccgatg atcaaaaata
     5641 ccgcaagggc tcccgtccat tgtccaaagg atgccagtag cagaccaagc aagccttttg
     5701 gataaaactc gaagaacaat gtctttctct ttagataagc aaaaaagaaa atgactggtg
     5761 ctaaaaaact accgccgaaa agccagatcc aatagcttcg aaaaatactt tctgactgaa
     5821 taaaaaagac atcaataaat gtaagaaacg accatacaga caaaccagtc agcataaata
     5881 gtgcgacttt tgatacagtg gctaaaacca tttttctatt tgtctgcttt ccataaaaac
     5941 tagcccgcag acttgctcct accacaccac caaaaccggc gagattgttg atcgtgtttg
     6001 ttacccacgc agcaagaaga aactcttttc tttccatttt tggttttcct tgtttttcta
     6061 agactctgat cgtcacccaa tcatacaaca acatcggagt gacacccagc agtccagcca
     6121 gaatcatgag caggatcgtc atgcggcttt gttgtcccat cctttgccaa atatcttgcc
     6181 aactcatgcc attagcaata tttgcgactt gatttgccac aaagactaac acggagccga
     6241 aaaaaatcag ttttaaaatc agactatgtt cctttatcca ttgcagcatc aagtatcgtt
     6301 tatttttcac attttcccat tcctaacttg tatacttttg tgtcataccc caatgttatc
     6361 ttatttattt taatttttcc actttagacc tgttctttgc ttgcgatgat agaaaaagaa
     6421 agatatccta atgctaaagg agaggataac atgaaagtag gatttatcgg cacagggaat
     6481 atggcacaag ctattattga tggtttatta aaaaaaggaa cagtctcgaa agaagaggtg
     6541 ttcgtttcca gtggacattt tgaaaatgca caaaaatttg ctgctgaaac tggcgtccat
     6601 gcatgcaaaa gtaatcagga agttgcatca caatcagata tcgttctttt agccgtgaaa
     6661 ccaaaaatca ttgaaaaagt attggaagaa ctaagagaat atagccagaa agtcttattc
     6721 atttctattg cttcaggaaa atcattaaca gatttagaaa cagcgcttga agatcctcag
     6781 gcctccatcg tacgtgtgat gccgaatgtc aatgtcagcg taggagcagg cgtttctgcg
     6841 atttgcaaaa atgaagctgc cacggaggaa cagcttcagc aagctacgat gatttttgaa
     6901 gcaatcggca gcgtctatcc tttagcagaa tcagatttca gtacattcat tggccttgct
     6961 ggcagctcac ccgcattcgt ttacatgctg atcgatgcga tgggacggac tggtgtactg
     7021 aatggtttgt ccaaacagac agccactgag attgctgcaa aagcaattat gggttcttgt
     7081 caaaaattcc tttcaagtga taaaaatcca tgggaacttg tagaccaagt ttcttctcct
     7141 ggcggtacaa ctgttgcagg tgtagttgcc ttagaagaag caggattcat cccagcaatc
     7201 atcaaaggaa tcaatacgac gatcgagaaa gatcttgaga tgttgaataa aaaataatga
     7261 tagcaatgtt ttttcgtgcc ttacaaaaaa agaagagctg tggcttttgc cgcggctctt
     7321 cttttgtatt ttttattatt tagcataatc agttgcacga gtttcccgaa taacgattac
     7381 tttgatgtgt ccaggataat ccagttcttc ttcgattcgt ttacgaatat cacgtactaa
     7441 acgaacagcg tctaaatccg agatttcttc tggcttgacc attacccgaa cttcgcgtcc
     7501 agcttgaact gcgtaacttg attctacacc ggcgaagctg ttcgaaatat tttccagact
     7561 tcttaaacga cggatgtagt tttctaatga ttcacttcgc gcaccaggtc ttgctgctga
     7621 gagcgcatct gctgcagcta caaggacaga gataacagaa gtagcttcca catctccatg
     7681 atgagaagcg atcgcgttga ttactactgg gttttctttg tacttggcag ctaattccgc
     7741 accgatctca acgtgagatc cttcaatctc atggtcaagt gctttcccaa tatcatggag
     7801 caacccggca cgttttgcta attggatatc ttcgccaagc tctgctgcta agataccagc
     7861 taattttgca acctcgaccg aatgcttcaa gacgttttgt ccataactag ttctgaatcg
     7921 cagacgtccg atgatcttga ttagatctgg atgaagtgta tgagcaccga cttcaaacgc
     7981 tgcctcttcc ccgtattcgc gaatacgttc atccatttct ttacgagatt tctcgaccat
     8041 ttcttcgata cgcgctggat ggattcgtcc atcttgtatc agtttttcca aggtcatccg
     8101 tgcgatttct cttcggattg gatcgaatcc ggaaagaaca actgcttccg gtgtatcatc
     8161 gatgattaaa tcgataccag tcagcgtctc aagcgttcga atattacgac cttctcgtcc
     8221 aatgatacga cctttcattt catcattcgg aagggtaacg actgaaacag tcgtttctga
     8281 aacttgatct gctgcgcagc gttgaatcgc taatgataat aagtttttcg ctttgcgatc
     8341 tgcttcttct ttggcacgct gttcagattc ttttaccatt agagttaact catgattcag
     8401 ctcttcttca gtcgatttca tgatgacatc tcgtgcgtcc tcttttgata aaccagcaat
     8461 tttttctagt tctttttgtt gatcttcaat cattttttca acgtcttttt ctcgctcttc
     8521 aattaattgc tgttttgaac taagtgcttc ttctttactt tcaagtgagt tctcgcgttt
     8581 ttctaacgag tcatctttac gattcagcgt ttgttcgcgt tgaatcaaac gattctcttg
     8641 agattttaat tctaacttac tttctctcag ctcactttca acttcagaac ggtatttctg
     8701 attttcttcc ttagcttcta acaatgcttc tttttttaga gtttctgctt ctttttttgc
     8761 actatcgatg attccagcag ctgatgattg tgcaccagct atttctttct cgtgacgtga
     8821 ctttgcgacc ataaacccta aaccaagacc gacaattaaa ccgatgatag cgaggagaat
     8881 gttgaatacc ataaaatcca cctccatact atctttttca tttttatcat ctatacagct
     8941 tctatgataa attattctaa actcgtcaat atgcatcttc gcatatatgt gtacaaaaaa
     9001 catgcacaac tttattctaa tgtttgtacc ccgtagtgtc aactttaaat aaacaaagaa
     9061 acggctttct acttattcat taaacgatgg tttttaaaat aaatgacact agtttcatat
     9121 aggtaaacct ttaaattgag aaacttttct attaaattat tctttgtaga tgaacagata
     9181 tttttatttt atgtacccac tcgtataatt aaataactca cgatttcttt attcaataaa
     9241 aaaacggcag gtcaaggaga gtacctactc ttcagaccag ccgtttttgt ttatcataat
     9301 ttttattctt ctactaaagg caattcttct tgtccttttt catcttctgg gacagcgact
     9361 tcttcaccaa taccataagc tgctctaact agagcagaaa cttctgccat catttcagga
     9421 tgattagcca tatagatttt agcgttttcc cgtccttgac caatccgatc ttctttataa
     9481 gaataccaag caccgctttt atcaacaatg tctttttcta ctgccatgtc tagaagttct
     9541 ccttcttgtg agatccctaa accatacatg acatctactt cagcgatttt gaaaggaggt
     9601 gctactttgt tttttacgac tttgatcttt gtacggttac caacaatatc tgtaccttgt
     9661 ttcaattgtt ctgcacgacg tacttccaaa cggatcgttg cgtagaattt caatgcgcgt
     9721 cctccaggag tgatttctgg attcccaaac atcacgccta ctttttcacg gatttggttg
     9781 atgaaaatag cgattgtttt tgttttgttg atcgaaccag agagtttacg caatgcttga
     9841 gacatcaaac gtgcttgtaa cccgacatgt gagtcaccca tttcgccgtc gatttctgct
     9901 cgtggaacta aagcagcaac tgaatcgact actacgatat ctacagcccc acttgatact
     9961 aaagcatcag cgatctctag accttgttct cctgtgtcag gctgtgaaag aagtagttca
    10021 tcgatattca cacctaattt ttgtgcatat tgcggatcta acgcatgctc agcatcaatg
    10081 aaagcggccg ttccgccatt tttttgtact tctgcaatag cgtgtagtgc aactgttgtt
    10141 ttacctgaac tttcaggtcc atatacttcg atgatacgtc cacgggggta accgccgaca
    10201 cctaaagcga catctaacgc aagagagcca cttggaattg tagagatttg ttggtcgatt
    10261 ttttcgccca atttcataat agagccttta ccatagctct tttcaatttt tttcagtgca
    10321 gcatctaagg ctgctttacg atcatctgcc aatacgataa tcctccttat atttacaaat
    10381 cagagcaaca tttcattatc cttatcatat cttttttagt gaaaaaaagc aagaaaaaac
    10441 cgaacaaata ttcgcattta tcattttctt aaaagctgtt ttctcaaaag atcaaatcct
    10501 tgcataaccg cattatatct gatagcagca cgatctctgg caaagtgata tttttccgaa
    10561 accacgccgt ctttagatga aatagcgatc catactgttc ctgcagattg accttctaac
    10621 gtgtccggtc cagccactcc ggtgaaagct acactgtaat ctgttcttgc tatctcacgt
    10681 gcttgaatgg ccatctgctc cacacattct ttgctgactg ttccatattc tgctaatagc
    10741 tccggatcaa tctccagaaa accagctttt gtttggagcg agtaggtaac gaatccgcct
    10801 ggaaatactt cagatacacc agcaatgtcg cctaatgcgg cttggaaggc gccggctgtc
    10861 aaactttccg ctgctgttac agtctgcttg ttttctttca gtagttccac tacgactttt
    10921 gctagcgaat tatcatcgcc gtatccataa aaatattccc ctactcgttc ttggattttt
    10981 tcttctaatg ctaaaagagc ttgattccct gcctgaacat catttgtttt cactgtcagt
    11041 cgtaatgtca cttcatttgg tttggcatat ggtgcgatcg ttggattgat ctgtgtctca
    11101 atcagatctt ttagctcagt gaccagtcgc gattcaccaa tcccataaaa gcgcaaaact
    11161 ttagaaatta gtttttcttc agaaggaaaa cgttcctcta gtaaaggacg tacttgttcc
    11221 acaaacattg gtttcaactc attaggcgga ccgggaagaa ggatatacgc atgtgtatct
    11281 gtttgataaa aagtccctaa agcaagccct gtacgatttg gtagaggaac cccgccttcg
    11341 ataatctggg actgttgcag attgtttttg gtcatttttc gatgggttgt ttcaaaatat
    11401 gccaataatt ttttgtatcc ttccgtattt tgtatgagag acttaccgag gtgagccgca
    11461 gttgcttctt ttgtcaggtc atcttctgtc ggtcctaatc cgccacataa gagtatgagt
    11521 tcacttcttg tttcagctag agcaatcaac tcttctaaac gctgctgatt atctcctaca
    11581 actgtttgat aataaacttc gatacctaga tcagctagct gttctgacaa gaaagtggca
    11641 ttcgtattca cgacttgtcc tagtaaaagt tctgttccga cagctattat ttctgctttc
    11701 attacttccc gctcccttat atagtatacg ctgtattttt atattttttt atttaaaaag
    11761 agggcaagga gctgtgacaa aaatcttgtc acagctcctt gttccaaata aacagtgttc
    11821 tcctgccaaa acctcggtca taagtcacaa tatacataaa acatgaaaag ctgttttttg
    11881 aaattatccc ttgtgactca gagttagacg gcaggctcac aacctctcca ctaaacgata
    11941 cttacattga tcctttgaac acaccgctgt ttttgatgaa gtaatccaca cctgaataga
    12001 tagtaaagat cagacaagca taaagcatga tttgatctac tggaataccg atcaggctga
    12061 atgggatatt attgataaac agcaagataa tagcaaccat ttgtgtagcc gtcttgactt
    12121 ttcccggcca agctgcagcc atgacttctc catgttcgac aagtagtaaa cgcaagcctg
    12181 tgacggctaa ttcacgacag acaatgatcg ctactaccca accaggggcc tttccttggt
    12241 caaccaacat gataaaagca gtcataacta gcattttatc tgccaacggg tccgcaaact
    12301 tgccaaaatt agtgacaagg cctcgcgcac gggcaatttt tccatctaac cagtctgtga
    12361 tactagctaa agcaaaaata actgcaccta ctagctgtgt gacagccagt gtggtgtctc
    12421 ctacgttaaa ttgtccccaa tctaaaggta aacctacaac caaaatgaaa atcgggatca
    12481 tacaaattct aagtacagtt aatttatttg gtaaattcac actatcgact cctttcttcc
    12541 ctattctacg tgactatcag cgaagtttcc accgatatta tttacttttc caaatgaatt
    12601 tattcaaagg agtattttta ttgaaattga tctttttgaa ttaacgaaga aggaccgcga
    12661 cacagatttg tcacgatcct tcttttttat acctacaagt aaacagatgc gtaaactaat
    12721 ttatacgatc attctgcgta ttgaagagta aggttcacat tttttggact ctgattgttt
    12781 tcccctggat taactggtac ggattctcca ttcgctttga tcgttgcatt gcttgctgca
    12841 ccaatcgtga tggtcgcatt tgttgctgtt tccggtaaca cggtactctg tgtttcattt
    12901 gctgccagtg tcccttgata aacataggca ttgtctacta gcacacctaa ccatacacga
    12961 ttgacagcag taaattcaag ggttacaggc ttggtagcgt ctgtgatatt tactgcgatg
    13021 gcactgccag aatcttctcc tgtagctatt gccattttct tttcttcact tgattttgtt
    13081 gttgattcta ctgtagaaga ctctttggtc tgcgtgcttt gctctgagga agaggactcc
    13141 tcgactgatc cttctacttt aagcgaagaa gctgtgtctc cgattattgg atcagcttga
    13201 cgatcttgcc aagtcatata gcccacgaca acgacaatcg ccaaagcaac caatcctaat
    13261 aaaatgacag gaagacttgt ccaaaagcga cttggatgcg attcttcctg atgcattgct
    13321 tttctagaag tacttactgt ttcaggctgc ggacgttcag ggaccgatcc tgtcaatttg
    13381 cttttcccat caaaaacatc gactaaatgg tctccatctt ctcctacagc ttcagcgtat
    13441 tgccgaataa atgcccgcac gtaaaattta ccaggcaatt ggtcaaaatc atcattgtcg
    13501 attgcttcca aataacgttt ttgaattttt gtaatctgct gtaattcatc taaagatatt
    13561 tttttattca ggcgtgcttg ccgtaatttt tctccgatgg tttcaaaagc cactcgttca
    13621 tcttctccag tctgtttgat tctccgaagc atctgctgtt gcaacgaaag acgttatgtt
    13681 tgggtgctgt gacaaaagtc atgtcacagc tccttttttc cgaataaaca ttgttctcct
    13741 gccaactcct cggtcacaag tcacaatatc caataaatat aagaagctgt tttttgaact
    13801 tgttccttgt gactcggagt taaacggcag gctcacgacc tctttcttaa acggtgttca
    13861 atcagctgtt cctcggtatt agctcaaaaa ccggcaaaat ataaggagat atttttccgt
    13921 atgtttctct aatactcagg tcaaaacgct gatttcacaa cctcttcctt aaacggtgtt
    13981 caaaagcttg catctgcggt aataagtcca accaagttaa aaacattaag aagctgtttt
    14041 tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct tggtacacgg
    14101 tgttccagaa gtagcttctt cggcaataag ccgaaatatc acaaaaattt gagaagcaat
    14161 tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tctttgatta
    14221 cttcgtttga ttttatttta atataagttg attaaaagag agcatgattt gttttatttt
    14281 ctcactaatt tttccaacac aactaagaat accataaaag ctgattttgg aggaggttcc
    14341 tactacaagt ctaaaacgaa atttaagact tttcctcata aatactggtt tattttggtc
    14401 tcatgtaaaa ctcgctgaag gcctcttcac ttataaatgc ttccccagct gccagtacgt
    14461 ctttcatttg gatcgaatcg atgatttcag gaagatcaaa taaagttcga tcgccaaata
    14521 aactttgcgt aaattgattg gcaatatatt cgatcgaatt taatgattgg aaatattgtc
    14581 caagcatttt cttcttcagc aaatcgagat ttgtttctga cacttccgga tcatcagcga
    14641 atccaagaat gatttctttg actttttctg ctgctttctc tggttcgtcc gtatctccgc
    14701 tgaagtccgc aaagtgaaat tcacgatcca agctgaattc aaaaccaaag ctgtcatcga
    14761 taattccttg attgtacatc gctagatagt ttcgagaagt attgcctaaa atcatttgga
    14821 acaacagatt gattgctgtt ttatagcgta acagttctgt tccttcttgc ggcaatgtgt
    14881 ctaatccttt aataccaagt acaaatttat ctcgtgtaat ggctgcttcc aatgcacttt
    14941 gtttgatgat ttcttttgtg ttttcaggga aataacgtac aatttcttgc tttggaggga
    15001 aattttttgc ttcttggttt tcccgaataa gtttcatcaa tttctcaggc tccatcttac
    15061 caactacaaa taaaaccata ttgcttggct gataaaacgt ccgatagcac gtatacaagt
    15121 cttgagctgt gattttgtcg atactttcaa ccgtgcccgc aatatcgata tgcaatgggt
    15181 gtgtaggata caagttattt agtatgccaa aaaacatccg ccagttaggg tcgtcttcat
    15241 acatttggat ttcctgaccg atgattcctt tttccttgtt tacagtttct tctgtgaagt
    15301 aaggtgcttg tacaaaatcg atcagagtcg tcagattctt ttctacctga tccgtcgtag
    15361 aaaacagata gctggttttc gtaaaacttg tgaaagcatt ggcggaagct ccttgtttcc
    15421 caaataattg aaagacatca ccatcttctt tttcaaacaa cttatgttct aaaaaatggg
    15481 caattccatc tggaactttc accttttctt tttcaccata gggaataaat tcgttatcga
    15541 tcgaaccata attcgtactg aacaaaccat atgtcttgtg atagtcattt ttaggcaaca
    15601 aatacacggt caaaccgttt ggcagtactt catgataaag tgtttcattg atttgctcat
    15661 attctgtttt attcatttgc atttcctcct gctaaaaaga agattgcctg caattcgatt
    15721 tgctcagcta cttgttgtat ctctttgatc gttacgctct ccatacgttt caaccattct
    15781 tcatcagata attttgtttc cggcagccag ctgtccaaaa aagaagcttc gattgccgct
    15841 tgcggagagt ctagagaaag cagatattgg tttctcagca ttgcttttgt ctgagacagt
    15901 tccaactctg ttatttcacc atttcgcaaa ctttctaatt gctcgtgaat cagatgaagt
    15961 acttgatttc ggttcttttc atcgataccg gtttggacac tcatgaatcc tcggaacgta
    16021 tccacgctac tagaggcata ataagctaga ctttctttct ctctgacatt catgaaaagt
    16081 ttagagtgag gaaaaccgcc aaataaaccg ttaaagacca ttagcgcaaa acgttctggt
    16141 tcatcgtaat acacatttgt ctgataagct aggttcagct ttgcttgaac gattggctca
    16201 cgtacttgtc gttccttcac gatattcact tgaggttggg tataaaacag atctggataa
    16261 actgtttccc gcgactcaaa tggtaattgc ccaactgctt cagctgcttt gtccggatca
    16321 acatcgccga caacaaaaat gtcgatttga tcatttgcca tcatttcttg atagtaggac
    16381 gctagcgaac tagcagtgat cttgtccaaa tcttcgacta cgcccaaccc tgggatcttt
    16441 tgttccgggc tgttttcaaa ataaagttct tgcaaggcat aggaagcaaa agtttgttta
    16501 tcttccttca aactttccaa atatagacgc agattgttct tttccaagtc aaacgtcaac
    16561 tgatcaaact gatgattttt aatatttgga taaaataaaa cctcttttaa aaaatctacc
    16621 gcttgagaaa aaaggtttgg atcattgaca tattcaccat tcacaaaact gatccctgcg
    16681 tttagccaat gtaaatttcc tttttttcta actgataatc caaagcttgc gccataaagc
    16741 tctgcaagtt gcgcacttaa ctttgtctga tccggataat tcaaactatt tgtttccaac
    16801 atgctgctga gaagtgaacg tttcgtgatg acttcttgtt gcagacgcgc agtaaaacgg
    16861 ataaaaatcc ggatcgtttt gtattgtttt gttggtaaga catgaagatt cacgccttct
    16921 gccaattgat acaccatatt tatatgctcc ttttcacagt tgattgcccg cttactcttt
    16981 taatgggtca acctgccttt tttacttatt cctctgcttg aaatttataa gttcaggcaa
    17041 ttcgccgttt tttctaaatg atgttacact ttatagtata gcatagatgt tttttatcaa
    17101 aagaaacaga cggctaaaag cgtatattgt ttttttattt tttatttttc gatatactaa
    17161 agacaaataa aagaagggag ggtcattcat gatcaaagaa ttcaaagagt tcatcatgcg
    17221 tggagatgtc ttggatcttg ctgtcggcgt tgttattggt agtgcgttta caagcatcgt
    17281 aaaccaagtg gtgcaaggct tgatcacacc actaataggt tggtttgtcg caatgatcac
    17341 aggtacttct gatttagaag gagcactttc aattcttgac tggtcgccga caaaaggcgt
    17401 cacatttgcg tttggtaacg ttattagtgc tatcattaca tttctgatca ctggttttgt
    17461 cttattctta gttgtcaaag cggcaaaccg tgcgaagaat ttacgctcca aagaagagca
    17521 agtggaagtg gaagaaactc ctactgcaga agattatctt agtgacatac gcgatcttct
    17581 tgccaaacaa gtggcagaag acaatacaca tccagtagag caaacaaatc tttccgatac
    17641 ttctaaataa taaagaatct aaaaaaaaga aagccgattt tcagtgtcgg ctttcttttt
    17701 ttagattctt aacttgctac ttgttccttt ttcatgtcga tatgtggaat atcatcttcc
    17761 aaatacacat ctgagattgc cttgaatcca aacgactcat aaaaagcttg taggtattct
    17821 tgtgcgccga tcacgattgg tttttctgga aaatttttct ggatcatgtt aatcgtttct
    17881 tgaacaatct ttcttcctaa accatcttta cggttgtcct gatgaacaag gacacgtcca
    17941 aaatggatac tctccgcttc ttcatatact cgcgtgtagg caaggatctt cccatcagta
    18001 tcttgaaaaa acgtatgcca agcttgtcca tcaatgtcat caacttcttg ataaggacac
    18061 tgttgttcca caacaaaaac tgcgattcgt tctttgacga tcgcgtaaaa ctctgctgtt
    18121 gacaattctt caaatttctt tacctgatat tccactaagc aaacgccccc tgctttttta
    18181 ttcttagcat accgattcgc acacaaaaaa gcaaacgaac cttacgaatc
//
LOCUS       DACCVZ010000058        17746 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.058, whole genome shotgun sequence.
ACCESSION   DACCVZ010000058 DACCVZ010000000
VERSION     DACCVZ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17746
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.058"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            201..1166
                     /locus_tag="IVW63_001950"
     CDS             201..1166
                     /locus_tag="IVW63_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAP7860220.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(1265..2437)
                     /locus_tag="IVW63_001951"
     CDS             complement(1265..2437)
                     /locus_tag="IVW63_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7860221.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(2424..3569)
                     /locus_tag="IVW63_001952"
     CDS             complement(2424..3569)
                     /locus_tag="IVW63_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7860222.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(3583..4515)
                     /locus_tag="IVW63_001953"
     CDS             complement(3583..4515)
                     /locus_tag="IVW63_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860223.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            4632..5711
                     /locus_tag="IVW63_001954"
     CDS             4632..5711
                     /locus_tag="IVW63_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP7860224.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            5708..6326
                     /locus_tag="IVW63_001955"
                     /pseudo
     CDS             5708..6326
                     /locus_tag="IVW63_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(6436..6663)
                     /locus_tag="IVW63_001956"
     CDS             complement(6436..6663)
                     /locus_tag="IVW63_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP7860225.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(6766..9354)
                     /locus_tag="IVW63_001957"
     CDS             complement(6766..9354)
                     /locus_tag="IVW63_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAP7860226.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(9374..10033)
                     /locus_tag="IVW63_001958"
     CDS             complement(9374..10033)
                     /locus_tag="IVW63_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP7860227.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(10082..10585)
                     /gene="trmL"
                     /locus_tag="IVW63_001959"
     CDS             complement(10082..10585)
                     /gene="trmL"
                     /locus_tag="IVW63_001959"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAP7860228.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(10806..11672)
                     /locus_tag="IVW63_001960"
     CDS             complement(10806..11672)
                     /locus_tag="IVW63_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP7860229.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            11781..12422
                     /locus_tag="IVW63_001961"
     CDS             11781..12422
                     /locus_tag="IVW63_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAP7860230.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(12484..13845)
                     /gene="mgtE"
                     /locus_tag="IVW63_001962"
     CDS             complement(12484..13845)
                     /gene="mgtE"
                     /locus_tag="IVW63_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAP7860231.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(13863..14762)
                     /locus_tag="IVW63_001963"
     CDS             complement(13863..14762)
                     /locus_tag="IVW63_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP7860232.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(14764..15561)
                     /locus_tag="IVW63_001964"
     CDS             complement(14764..15561)
                     /locus_tag="IVW63_001964"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HAP7860233.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(15539..16243)
                     /locus_tag="IVW63_001965"
     CDS             complement(15539..16243)
                     /locus_tag="IVW63_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAP7860234.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            16374..16949
                     /locus_tag="IVW63_001966"
     CDS             16374..16949
                     /locus_tag="IVW63_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HAP7860235.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            17067..17744
                     /locus_tag="IVW63_001967"
     CDS             17067..17744
                     /locus_tag="IVW63_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAP7860236.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         5250 a         3806 c         3153 g         5537 t
ORIGIN      
        1 ttttttgtgt ttttcggtct tcggaccttt ttcattttcc tagacttctg ctataataac
       61 caagaattaa ttttgtaaca gatttttttg aaaaaacaag tttctttcat tcaaaaaata
      121 gaaaaagctt gctaattatt ggttaaccag caaacaggag tattaaaata tcttgtttta
      181 ttgaatagca ggaggaaatc atgaaattcc attatcatat attgatcaat ccatcggcag
      241 gcagcggaaa tggctataaa gtagcagaaa gaattttacc ggtattaaaa aataagcata
      301 ttgactatac acttcattat agtgaataca aaggacacga tgctgagatt gctgaaactt
      361 tggcaaaaga aacattgatt ccttggatag aagaagaaca gaaaacaatc gatactttcc
      421 cccttttgat catcgtagga ggtgacggca ccttacatca ggtacttgat actttctatc
      481 agatggaagt agaattccca gttgcttata ttccagcagg ttctggaaat gattttgctc
      541 gaggggcagg ccttccaaaa aatcccaaaa aaggacttca gctgatttta gcagctcaat
      601 caccagaaaa agtccacata atggcttatg aagaaaaaat aagtgaaaaa aaaggaatag
      661 ctgttaataa tttcggtata ggattagatg cagctatcgt ccatgcgaca aatcattctt
      721 ccacaaaaaa gcgattgaac aaatacaact taggatcatt ttcgtattta ttctctattc
      781 tccgtgcttt attcactcaa aaaggatttc caattctggt agatgcagga ggaaaacaat
      841 taagtttttc aaacgcattt ttatgtacag caacgaagca tccttttttt ggcggaggaa
      901 tcgcgattgt tccaactgct gatgcgtcta aaccagtcat tgattttgtc gtggtcgaac
      961 gaatcaattt ctttaaaatc ttgtggctca ttcttttact tatacagaaa aaacaattga
     1021 aatcgaaata tttccatcac tacacaacaa acagattacg tatcgtttca acaacaccgc
     1081 aacatggtca agaagatgga gaagaaatgg aaaaacgacc ttttgatatc acaataacca
     1141 caactaaaca gttgttttgg tgttaataaa agaggttttg tcagaagcta catctggaac
     1201 accgtttatt cggaaaaaag gactgtgaca cgacttttgt cacagtcctt tttttactat
     1261 gcagttaatt ctttgcccaa ttgggttgcc atcgatagtt tctttcttta cccaaaataa
     1321 attggatcat tgaaaacacc gcagcaaaag caactaagac acaaccattg aaccaaaaag
     1381 attctgcaaa tgtttgattg taactgagtg tttcactgat caagttatta ttttgaacaa
     1441 accaatatgt tggtgtgaat gccgctattt tgctaaccat ttctggcaag tattctgctg
     1501 gtacaaacac cccaccgata aagcaactgc ctgtgataaa aatatctttg atcccaccgc
     1561 tggtttctga gttttttacc aatgaagtga tacaagccga aaagctaatg atcggcaata
     1621 aaaacaagaa agtatttaaa atatgatacc ataccgttat atcccacgag gtgtggatca
     1681 ctaacagaac cattagaagt aagaagccac tgaacaacag cagcgagtaa ctaatcaaac
     1741 taaaggttac tttgcgattc aagtttcgtt tggtaatggg cgcactctgg tttcgtttac
     1801 tgatctcttt gcgattaaac gctagattga tgacgctgaa accgctaaaa atggatagaa
     1861 acaacccata agacaagaaa ttaaaggttg tgcccgtcaa cagctttttc atccgctgac
     1921 tatatcccgc acttagctca acttctccag taaccgagag tgccatttgt gtctgttcca
     1981 tagctgcatc gattgtttta tcttcttctt gaaacagaat cagtgtttgc aaaaaggtgt
     2041 tcacttgctg tgtaacaact gttttagaaa aggcatctgg gcgactctgt atcttgatcg
     2101 tcgccatctt tcctacttcg acttgttcgg taaagtctgc aggcagatgt aagataatgt
     2161 ttacacgatt aaaataaaga gcatcatcga tttctttttg tgaggttcca tccaatgtaa
     2221 cgactgtttc cttgtcattc aaatatttac gaaggccatc gactacaggc gactcttctt
     2281 cactaatcaa ggcgattttc gcatcttgca gagaggtatt ttcaacatca atattttgcg
     2341 caaaaaagaa tgtggcaaca acagtgataa ttacacctat cagtaaattc gatttatttg
     2401 ctttaagcaa tgtccaaatc gttttataaa gcgtcataac gcacccctct ttccatccaa
     2461 gcatttccta acgcaaaaag gaaaataaat ccgatcaacc atagaagatt ggtataaaaa
     2521 ctagccaaat cagtgtagaa ataaagttta tacaaacttt cgctgatcaa gttgacgaga
     2581 tttaattgac caacaatcgg aatatgaaga tcaatccaat acttcacttg ttccgacccc
     2641 atcataccag caaaaaagct catcgcaatc gtcactgaaa tcaagatgct atccttttgc
     2701 accagattca tttttggtat caaattacca accaatgtac ctaacaaaat cgcacacaac
     2761 gaccccagag cggtaacaat catcaaccat tgccaacgtt caccaaagtc tacttgatag
     2821 ataaaacgaa agacagctaa cataatataa atctctgtca aaacaatcgt aaagcttgct
     2881 gccaaattag cgattgaaac taacgattgc tttctaggaa tcaaggacaa gcgaatacca
     2941 tttgacgatt gatttgcttg ctgatcctgt acattgcgga ccccccacat cgtcccgtag
     3001 agaatcgcca ttccaatcag agtgaagaaa taaaaacttt tgaaactcat attacgacct
     3061 gcatgaactt cttgaaaaga tacttcttgt tcaaaaacag tcatgatggg cgcgagatca
     3121 acgttctcca cttctgccac tttactcgaa attataccaa tacgctgtaa aaattgatcc
     3181 atgacgtttt tcatcaacgt ctgactcatt cctgcttgac ccacatggag cgaaacagat
     3241 gaaccatcaa tgagataaaa accagccaaa tcatctgcat ttagcttttc attcgcttct
     3301 acttccgata gttcctgtac ttcaaataat ggtttatcat tgacttcgac ttgttctaag
     3361 actgtggtaa aattttccga aagcgctgtt tgatccgctt tgattacaat tccagtatta
     3421 atcgtttcaa gattgccacc ttgatcaatc tcgccaaagg ccgccataaa catcaatcct
     3481 aaaagaattg gaaaggccaa tgtccaaaac aacatggatt tatttcgcag cagtattttt
     3541 gtgcgatatt tataaaaatg ccaaaacatt atttcccctc ctctagtctc tcaaatcctt
     3601 gccagtaatc tctaaaaaga catcattcaa ggacgcttct ttggttgcta tttttccgta
     3661 actgatcttt tcttcttgta agattgtaag aatcggcaac aatactgtat ttagttcagt
     3721 agttgttact tggagctgac cttttttata agcgattcca tcagaagcta ttgttcgctg
     3781 aatcgctgac aacacatttt ctgggagtaa tgggatgtcg atcgtcaaac gatccgccgt
     3841 ccgtaccata tcttttagag attctttggt tcctttagca atcacctgtc cttgatccat
     3901 gatcacgatc tggtcgcaaa gaatttctac ttcttccatg taatgtgttg tatagacaat
     3961 ggttgctcct tgtcgattca gctccttgat actttctaaa attttattcc gactttgggg
     4021 gtctacagct actgtcggct catctaaaaa aattaaccgc ggcttgtggg caatcccaca
     4081 tgcgatgttc aaccgacgtt tcaagccacc actaagttct cctggacgaa acgaaacata
     4141 tttttctaat cccactaatt gaatcacctc ttcaatcaag gctttccttt tctctttttc
     4201 ggaaacatat aaaccgcaaa aataatcgat attttcttgc acacttagtt cgtcaaagac
     4261 cgcaacgtct tgaggaacga ccccaatcat tgccttgaca gcataatttt caggagtcat
     4321 tgttgtcccg aacaatttaa tggttccttt gtcataattt aacaaagaaa gcatacagtt
     4381 gatggcagtc gatttcccac tgccgtttgg acctaacaga cctaagactt ctccttcttg
     4441 tacttgcaga tcaaaatgat tcaatgctac aaaatctcca tagcgtttga ctaatttatc
     4501 aatttcgata atcatcatga aaaactcctt ccaaatttct tgttgatctg actataataa
     4561 agtgcaagaa aagaaactag tgacgattgg ctaaaccaca catgacattt gtcacaatga
     4621 aggagtctgc tatgcataaa tctcggctac tcaacgaaac tagctttcta ctggttatct
     4681 cattgctttt gctggtaagt caaggattcg ttgctatgca agttatctat ttattgatcg
     4741 ccgttttatt cactggtgtc agttatttac tgcctacaaa gccaaattgg attttccaag
     4801 ttattctatt tcttttatgt gcctttttac ctgatcttgt cctgtttctg ccagcgacga
     4861 tgcgagtgat cgcccctgaa gaaagccacc ttgattactt gtttttgtta ggttttttgt
     4921 tgatttcgac ggttggtaat catcccccca tcaaggtcgc ctttgtcgta attttgctgt
     4981 ttttttcctt ttacttacga aaaaaagatc aacgaacgac cgatcttgag aaaaagtaca
     5041 ttgtctccaa agatactcat tgggaaaaac aacaagagtt atcggaacaa aataaagcat
     5101 tggccctgtc acaagaaaca caattagcct tgcaaattgt ggaagaacgg aaccgaattg
     5161 cccgagacat ccatgacaat gtcggtcatc tgctgtcaag tgcgatttta caaattggtg
     5221 cgcttgaaat gatcaatcaa gaaccaaaac taaaagaacc attagaaaat ttaagtgcca
     5281 ccgttcacac tgggatggat cggattcgtc aaagtgtcca tgacctccat gagacatcga
     5341 tctcttttca acactcctta gagtttctga tcgctgattt tccttcttct gttacgattg
     5401 aaggaaactt gtttgaagga ttgaatgaaa cgcagcaaaa ctgcttctta atggtcatca
     5461 aagaagcctt aaccaacagt atcaaacata gtcatgccaa aaccgttgtt ttacattttc
     5521 gaacgttgcc ggccttttat cgcttgcaaa tcacgaatga tggcaccagc ccacaaaaaa
     5581 attctgctcc cggtattggt ttgaaaacga tgcgtcaacg tgttcaagaa caaaagggac
     5641 aagtccatat tttccaagaa aaccagcaat ttcagttaac gatcatttta ccaagggagg
     5701 gacaccaatg ataacagtag tcattattga tgatgatcca tttgtgacga aatcgttaca
     5761 aaccatttta gaaagcacga aagagatccg tgtgttaggc attggtcatt gtgccaagga
     5821 tgcgcgaaac ccatcgtccc gatgttttgc tgacggacat ccgcatgcct aaacaaacgg
     5881 gcatcgatgc tgccaaagaa attttggcta aatttcccaa agccatcctt ttgcttttga
     5941 cgacattcaa agatgaagaa tacatccgcg aagcattttc catcggtgtc aaagggtatt
     6001 taatcaaaca gaacttgcaa gcgattattc cttctgtcaa atccgcttat aatggacagg
     6061 ccgtatttgg taatgaaatc atcgagactt tcactcaaat gatgaagaat aaaccgacga
     6121 ttgatagtca tgcttatgct tcttttagtg aacgtgagct tgcaatcatc aaagaagtag
     6181 ctgccgggaa aaacaataaa gaaattgcag atgccttgta cttgagtgac ggcactgttc
     6241 gcaattacat cagccaatta ctagaaaagc tagatttacg ggatcgcacg caattggcta
     6301 tctattttta tcagcatttg caataagtct tatctaacac aaaaaaacct gaatgatgct
     6361 ccttcgcatc attcaggttt ttttcacatc ttctattcaa ttgtcccgca aaccatttcc
     6421 tcacgattga aagaatcaag gattcgcagg gctgccagga ttcgttggat tgttcggcgt
     6481 gttaggcgga aaaataggcg ccttgtctaa cgttttttct agttttgatt cttcacgatc
     6541 gtctcgttct acatcaggac tttcattcaa tttgaattct ttttccatct catctaactt
     6601 tttaaagtca ttgccagatt cttttgctaa tttcgctaat ttatcttcgg tttctttagc
     6661 cataaagtaa cgcccccctt ttgatttcag cttagcatat cacactgaaa aaacaaaaga
     6721 aaacgctaac caacgatcat ttttagctat ttctcatctt taaaatcaag cattttttgc
     6781 cggtataaaa tcgtagggag aactgttttc cataccaatc atcggatcta ctaactggtt
     6841 atcgatcact tctgctgtaa gaacgaaatc tttagaaaca gcaggttcta cctcttcttt
     6901 cttttcttct ccaacaaatg aagaaaacag atctggttcc actgtttcca ttacttggtt
     6961 tttcgtttca ttcgtcccac tgtcatcttc tacaggtagc ttttctttta caacccgtgg
     7021 ctcttttgta tagttcccat cttcaaatgg atcatttccg accaaagaat cttcataagc
     7081 tgctagtttg gtccggagag tgatattcat tttatcatta tccatgatcc ttgatttcaa
     7141 cgtagtcatc cggcttgctg attcattcgc tacacaagtg acataggctt gctcttcccc
     7201 taacaaaatc aacagttcct tactgcgagt cactgccgtg tagagcaaat tacgctgaag
     7261 catccgctga tattgatgga ccatgggcaa aataaccatc ttgaattcac tgccttgtga
     7321 tttatggatt gagcaacaat aagaaagagt gattttattc cattcgtttc ttttataagt
     7381 gacctcattt gcatcaaact ggataactaa ttcatccact ttatcttcag aatcttttgc
     7441 caagatgata cccgtgattt ctcccatatc tccattgaat acattcaatt cgggagtatt
     7501 gactaattgg aggactttgt ctcctatccg ataaacggtg tcgttccaat gtacttcctt
     7561 ttttccaggt ttccctggat tgaatatctc ctgcatcatt ttatttaacg catcgatccc
     7621 tgcaggtccc cgatacattg gtgctaatac ttggatatct tgtgcacgga atcccttatt
     7681 tttcgctttt tccacaattt tagagatcaa gggttcaatt tgataagcat cacttcggaa
     7741 ataggaacga tctttttgat tctttgtgaa atcttttggc agacgtcctt ctttgatctc
     7801 atgggcaaga ggaataatac tagaaccatc accttgccga taaatctgat tgagttccat
     7861 tttgggaatt tgttcgattt ccaaaagatc atggagtact tgaccaggac cgacagaggg
     7921 aagctgatct ttgtctccta ctaagataac ttgcatattc gtcggaatcg ctttgaataa
     7981 tgtgttagcc agccatgtat cgaccataga catctcatca acaatcaaaa gtccgccttc
     8041 taattctttc gtactgactg aaggtgtttt ttcccgtcca ttcagcccca gaagacgatg
     8101 gatcgtactg gcaggcagac ctgtcgtttc gttcattcgt ttagctgctc ggccagttgg
     8161 tgctgcaagt agaataggaa aaatttcttg ggtatatttt gaaggatcca attccagtcc
     8221 gttcaactct gcaaaaagat tgacgattcc gttgatcaca gtagttttcc ccgtacctgg
     8281 tcctcctgtt aaaataaata gaggggaacg gattgcttca gcgatagctt gttcttgcga
     8341 aggtccatac tgtatgccga atattttttc gatacgccga atattcttct gcacttcttt
     8401 ttcaggataa tggatttctt ttttacgact gagaaggcgc tggatcgaat taccgatccc
     8461 ccattcagaa aagtacaaac tgttttcgta aagattagtc tcttcttgtt gtatctttcc
     8521 ttcttcaaca agttggataa ttacagtagc aacctgatca ggctggattt caattgggcg
     8581 acttgtttct aaaatacgga tcgtttgctg aagcaatgtc tccgccggta cgtatgtatc
     8641 tcctgtttga actgcatgct gaaaaatctg atgcaagata gctgctcgaa ttcttctcgg
     8701 tgaatctgct gcaataccga tttgttcggc tagattatct gcacgtttga acccgattcc
     8761 ttctatgtct tcgactagct ggtacggatt ttcttcgatg atatccaaag actcgttctt
     8821 ataggcctgg tagatactga aagctaactg actaccgaac ccgtaacgat tcagtcccat
     8881 gatcacttga tccatcccgt ggtttagccg aatcgtctca gcaagcattt ctctttttgg
     8941 cttcgtcaaa ccggagattt gttttaatac cgaaggatca gcaatgattt tttcgatagc
     9001 atcttctccc agcaattcta caattttttc tgctgttttc ttcccgattc ctgggaattt
     9061 ttcgctggaa agatacgcta cgatcccatt tgcagttgtt ggcttttctt gctcatatct
     9121 ttcgagttta agctgccttc cgtatttagg atgatccact aattctccat aaaaacgata
     9181 agtctcattt tcttgaatat cgccgaaact tccggtgact acaatctctt tttcacggta
     9241 atcagctgtg gtttcactga tgtgtaccaa aagcactttg taaaaattac taggattttg
     9301 aaaaaaaatc gcggcaactg taccaacgaa ataaggcatt tcttctggct gcatcggaag
     9361 ccgcctcctt cttctatagt aaaggttctg gtgctgtttc agttcctaaa aaatctgttt
     9421 ggttccatac tttcagttca tatggcaata atctgcaagg ctcttcagtc tctaaaatcg
     9481 tcaaactact attgaacaat ccacccattt cacgcaactc acttagctct tttcctgtca
     9541 tccattgaat ggctgcagtt aaagaagctc catgtcctac gaataaaagt gggccatctt
     9601 tatgtcgggc aaccgcatct gctacaacag tttcgatacg tgtgattgcc gattcaatcg
     9661 tttctccgtg aaaaggagaa ggatcataca gatctaaatg attacgcaaa ttcggcagat
     9721 tatccggata tttctggtac atttcatcga tcgactgacc ttctaaagta cccagcccta
     9781 gttctcttag cttatctgta taaaaaatct ctaccggacg agcaagctct ttgttgatac
     9841 cttctgctgt atcacgtgct cgctttgctg tactggaata aattgcttta aaaggaacat
     9901 attttacctt tttcccaaat gctttgattt cttcgtaact ttgtggcaaa agcggagaat
     9961 cgccattgct cccttgaaaa cgtctttcct gattccattg tgtcttccca tgtcgggtaa
    10021 aatatagttc catacgcagc aaactcctgt ctttctttta ttttactcta taataaactg
    10081 tctaatccag cttgtcattt tcatagtgat gcgtcaattc taaattaggg aatccttgct
    10141 ggcgaagtgc ttcatacact atcattgcag ctgtattcga taaattcaat gagcggacat
    10201 gctcatcatt catagggatg cgtaaacact tttcttcgtt ttcacgcata aatgtttctg
    10261 gcaaaccggt tgtttctttt ccaaataaaa agaagtgctc ttctccatca gcaaaatttt
    10321 cgtcactata tactttatgg gcaaattttg agatcaaatg tagtttacga ttacctaaaa
    10381 atgttaaaaa agcttctaaa ttactgtggt aagtaatatt tacatcattc caataatcca
    10441 accctgcccg ttttagatgt ttgtcatcag ttgaaaaacc tagtggctcg attaaatgaa
    10501 gcggagtatt cgtggctgca cacgtacggg caatatttcc agtgtttgca gggattaatg
    10561 gttcaaataa aacgatatga ttcatcagga tcattcctct catatttatg ttcgtttcta
    10621 ttttctgaca atttgatttt tgcataaaaa aaaacgtatc aactcggtgt cagtcactgc
    10681 gagtcgttac gttagtgaag ctcttctcac taacttttat cagaacagga acctgataaa
    10741 aaccaatgaa aaaacaactt gttgctaata taacaccctc aacttttttt tgcaacctct
    10801 actcattaaa aactgctaga aaaacgtttt ctcttagttc cttttaataa ttctatgtca
    10861 attgtaatct tcttcaaagg attcttatat aagtctgctt tgattcgctc ttctacctgc
    10921 cattctaaag gtgacatggc caaaagatct ttttgatttt cctctggtat ctcaaattca
    10981 taggttacac gctgacgttc agttaatttc attgcttcag caaacttggc tactacacgt
    11041 tcattggaat aactctgttt ttcaggttga ttcggataaa aagcctgacg tagttccttt
    11101 aaataatttt cttgtggcac caccttcaac acttctccat cttctgagag tacacgttgg
    11161 aattcttggt aatgagaagg cgaaaagata tttaaaaccg cgttgaatgt ttgatcagca
    11221 aacggcaaat tggtcaaatc agctacacac caaaatgctt cggcagattg ttctgtagct
    11281 gcgtagactc cttcttttga aatatcaaat ccaacagcat tttgaatctt tttcaatttt
    11341 gaaagttcat tcaagaagct accttctccg cagccaacat ctaatagcga gacttcttca
    11401 ggtaaatgct gcgcaatagt ctcaataacg ggctgataca tgccagattg gatcattcta
    11461 cgccttggaa cgaacattcc ttgatcgtat tctgttttaa ccgcatggga taaaaaataa
    11521 agtgttcctt ttttggaaag gtcaaaacgg tgattatttt tgcatatcaa gccattatca
    11581 gactttttta cttcttcttg gcaaaccgga cagcggaaca gctgatgatt ttctgccaaa
    11641 aactggcgtc ctcggtcaat tttttttaac atagttcccc ctcatttctg ttttatctta
    11701 ccgttagatg ctcactttgg caactgctaa aaatatgata caatgcctag aagaaagtga
    11761 aagataaagg agaagattag atgatcaaag aattttgcgc tgaaaactac acatctattc
    11821 ctctagcaat tgctagagga gccgatcgga tcgaattgtg tgacaactta gcggtcggtg
    11881 gcacaacccc gagtactggt gtgatcgaag aaacgttaag ttatgctggg gaaaaagata
    11941 tccccgtaat gacgattatt cgtcctagag ggggcgactt cgtctataac gatatcgaat
    12001 tgaaaatcat gcatactgat ttgattgaag caaagaaatt agggacggat ggcgtagtat
    12061 ttggttgtct tactccttca ggctggctag acgaagaggc cttagaacta ttgatcgaaa
    12121 cagcagaagg gttgcagatc accttccata tggcttttga cagtattcct gaagatcggc
    12181 aattcgaagc aatcgattgg ctggtagaac atggtgttga ccgtatcttg actcatggcg
    12241 gtcctgctga caaaactatt gtagaaaatt tcccacggct taaagaattg attgcctata
    12301 cagatggccg cttaatcatt ttgcctggtg gtggtgtcac tgcagagaat gcagcacatg
    12361 tagctaaaga attgaacgta agcgaagtac acggaaccaa aatcgtggat cttcagttat
    12421 aatcttataa acaaaaaaac atttgcaaca ggcataatgc ttattgcaaa tgtttttgtt
    12481 tttttacata aaatagccca taaataaaga agcaatattg aaataaatca gtacactcgt
    12541 caaatcgctc aaagtcgtga taaagggacc gcttgctact gctggatcaa atcctagacg
    12601 atccattagc atcgggatta aactacctgc aagattcgcc actgtgattg caaatagcat
    12661 agccatccct atgacaaacc ccaagataaa attatgtttc caaaaaccta cgattagaaa
    12721 aatcgtgatc cccgtaacag ctcctgtgac aacgccggtc aagacttcag ccaaaacaag
    12781 tcgaacaaat ccatgatctt tctcatcaga aatcgcaagt cgacgaacag ccacagctag
    12841 cgactgggtt ccagcattac cggcagttcc tgtaatcagc gaaatgaaga ctgctaaaat
    12901 actcgcttca cttaccaagt cttcatagtg actgattaaa gaagcggtcg acatacctaa
    12961 aaacaacaga gtgatcagcc aaggcaaacg tcgagacgct gcctttactg gattttcatt
    13021 aatttcttcc acattgaccc cggcaagtcc tgaataatcg ctagcagctt catcatcaat
    13081 aacgtcgatg atatcatcga ctgtgacgat tcctaacaaa tgatcatcat aatcggtaac
    13141 aggaagagct aagaagtcat aatctctaaa tgtttgtgcc acatcttctt ggtcgtcgcc
    13201 tacatgaact gaaagcactc gttcgctcat cagatcagaa atcattgcgt cgtcatcatt
    13261 cacgattagg tcgcgcagag aaataacccc tactagctga ccttcttgat taacgacata
    13321 gatgtaatag attgtttcag ctacatctgc ttcgttcttc agcacgtaca tcgcagagcg
    13381 aacagtttga ttggctacga tcgaaacaaa ttcagttgtc atgatcgcgc cagccgtttc
    13441 atcctcgtaa tggagaagtt ccttgatttc actggcatcg tctgccgaca tcaaacttaa
    13501 atatttagca atttgctttt tatccagcgt attaagcaag tcaacagcat tatctgtata
    13561 catctcagaa agcatatcag ctgcatagct aggacgcatt tcatctaggt attctttcat
    13621 atgttcgttg tcttcttcaa tcacatcgaa catatccgct aattctttag gcgacagata
    13681 ggaatagatc agctgcctgt tctcttctgt aagagattgg tagaattgcc cctgctcata
    13741 gatatgcatc tctaaaaaac tgtttctgaa tgcctgaata ttattttccc ttaaatcttg
    13801 agtcaactgg gcaaatcttt cctctaattc ttgattttca tccaaaccaa tctcacctcg
    13861 ccttattctt caaaccgtct cacaactgcc tccatgtctg cggctaaagg ctgcttgaac
    13921 tccagcaact cttctgtaaa tggatggtaa aaacgcagat cataacaatg aagggcttgt
    13981 ctttttattc ccagatccat tcgcccgcca tacatatcat caccgagcag ggcacagcca
    14041 attgcggaaa aatgaactct tatttgatgt gtccttcctg tatgcagctg gatatcaact
    14101 aacgcgattt ctgttagtcg cttctctatc cagtactcag tctgtgccga acgtccttca
    14161 tcagagacca ttcgcttcaa tagcgaagaa taatctcggg cgatcggcaa atcgatatgt
    14221 ccatgtgccg ataaatctga aagccttcca ctgactaagg cctgatattt tttcacaaac
    14281 ttcttttcac gaagttgcat atctaatttt gcgtgcgcaa atccatgctt tgcaaaaagc
    14341 atcaagccag atgtatcccg atctagtcgc gtcaccacat ggattacttg gttttcgtaa
    14401 ccttgttttt tataataagc ctttacacga ttagccattg tcccatttgg atggtattgg
    14461 gcaggaatag acgaaacgcc tgctggttta tttactacca gaacgtgttc atcttcatac
    14521 acgatatcga tcggtgtttc atccaaaagt acggtttcat gttctccttc agcaggaatc
    14581 acaatggtta ccttatcatc cttagctaga gaaaacaaga cattttctac ttgatcatta
    14641 actttgattt gaccgccttg aaattttatt ttcgctaaca gaccctttga gatccctttt
    14701 tcttttaaaa aatattttac ttgctgagaa tgatctttct cataatccca tgtaaactgc
    14761 atatcaatcc tcactaataa aggcatcttt cacacgatgc caaaaatgca tatgtcgata
    14821 agaagcaaaa tggatccgtt cttctgctat tcgataataa attgagcgga tatttgcttt
    14881 tgcgacattc aattgatcaa ccgttacaag ataatcttct gtattttcca attttatttc
    14941 tagccattca tcatgggcaa tcacgatcgg agaacccaaa gtacgaaaca ctcgattatt
    15001 cagtgaagca atctctgcca actgaaaggc attgatacta ggatggatca cagcaccgcc
    15061 gacactttta ttatatgctg tcgaaccagt aggcgtagaa atcgtcaatc catctcctct
    15121 aaaactttca aacagctcgt ttttgatgta tacatcggct accatcgtac gattggcccg
    15181 tttaatcgtt gattcattca gtgctaaaaa atgctggtcc ggtgtttcat ccaaataact
    15241 gatccgaaca tccagcaagg gataactaac actttgttcc cggttcgttc gtaagctgtc
    15301 tactagttct tccagctcgt aatcccgcca atccgtgtaa aaccctaaat gacctgtatg
    15361 cacgcccaag aaacgcacat cattcagaca atgactgtag tgatggaacg ccgacaataa
    15421 tgtgccgtct ccgccgactg agatgaccaa ttctggctca tgatcatctc gttgaatccc
    15481 tgcttgttct aaaagtgcgt tcaaacgttc tgtcacttct atagtctttg cttctttatt
    15541 atgaacgatc gctactttca tcccctgcct cctctctttc gctttctttc ttcaaaagcg
    15601 ttcgatagta gacatcatct gattttcctc ttccatggga gaataaccgc tgtgcttctt
    15661 ggatttcttc acggatactg gacatctctt catccaactg ataggcagct tctgccgcac
    15721 gctgaagtcg ttcactcatt tcttctggaa aaacgccttg atatttataa ttcagcgaat
    15781 gctcaatcgt tgcccagaaa ttcatcgcaa gagtccgaat ctggatttcc gccaaaattt
    15841 tcttctcacc gctgatcagc tgtacaggat actcgatcac cagatgataa gaacggtagc
    15901 cacttgcttt tttatttgtg atgtaatctc gttcttggag aactttcatg tcttttcttt
    15961 tacggatgat ctcaacaact tgatggatat cttctacaaa ctgacacatg atccttaacc
    16021 cggcaatatc agacatttct tcttctaaac gtcccattgg aatatgccgt aattgtgatt
    16081 ttgttacaat actatcgact ggcttgactc tcccagtgac aaattcaatc gggacatgtc
    16141 gattttgttc acggaactgt ttgcggatcc cccgcagttt cactttcaat tctgatacag
    16201 tttgttcata tggtgctaaa aatgcttccc aatctcgttc catagctgat acctctactt
    16261 cattaacatt cattgtttat tctaccatat atgcaaagtt ttttcgtact cttgatttat
    16321 gcattgacca aaaaaagaaa attaggcaaa atagacaaaa aggagtcgat caaatgacac
    16381 aaatgcttga aatcgaatat aaatctatgc tgacaaagca agagtacgag atattcatcg
    16441 ctcactatca attaacagat aaagatttcc gtgtacagac taatatttat ttcgataccg
    16501 ttgatgaaca gctgaagaaa caaaattgtg gcctacggat ccgtttcgtt ggtcatcaag
    16561 ctgaatatac attaaaaaca cctgctgaaa aagggcgtct cgaaacaacg gataccttta
    16621 taacagaaga agcagaagca tttatcttcg aaaaacgtct gcctcgttca ggcgcagttt
    16681 ttcaaaaact ttctgatttg aatatcgatc ctgcttcatt aatccaaacc ggaaagctta
    16741 caacaaaacg agctgaattc cctattgaag aaggactttt agctattgat gaaagctggg
    16801 gagacaatct acacgatttt gaactggaac tagaggtagg ggatgcatct gtgggaaaaa
    16861 ttgcttttat aaatttttta aaacgttttt ctttacctta tcgtcctgct aagaacaaga
    16921 tccaacgtat gcttgaagct aaaaattaga aacctttcat tttcacaagg cacttgagtt
    16981 cattttttta cttttttctg ttaagttata ggatgtgaaa gaatctagtc actagttgta
    17041 tagaatctat tttgggggag attcatatga tcgaaatcta tttatttgtt aatcctttag
    17101 gggaatactg tttcgaaatg gaacaacagt tattacaatt tatcgaagaa gagtacggga
    17161 caccatcaaa agaaaagatg caatttcgct ttcttccttt ggtcaatttg cagacaattg
    17221 gggatgtcat gcaacaaaaa ggaatttctc agaacaatct tgaggaacgt aatcacttat
    17281 tctcaatgac ttattctgca gcattggact gcaaagcggc gcagtttcaa ggaaagaaaa
    17341 aaggccgccg ttttttgatc aaattgcaag aagcagtcgg ctgtaatgac ataccatatt
    17401 ctcaagaact tgctgaatcc atatttgaag aaatcggcgg cgatttgaat atgtttaaag
    17461 aagatcgtca gtctgacttc gttaaagaag tattcttttc tgatcaaaaa attgctcggg
    17521 aaatgggcat cacaaaacac ccttctgcag tcgtttacaa ttatgcctgc gaccgtgatt
    17581 ttggtgtttt agtagaagta aaaggtacaa gtagcctttg gagaatcaca gagctgtgta
    17641 aaacaacaga taactcatat caagttttta atggtgaaca tttacataca aatgattctc
    17701 agttccattc aagaactagc catttacact tgctttctaa ttaaaa
//
LOCUS       DACCVZ010000059        17379 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.059, whole genome shotgun sequence.
ACCESSION   DACCVZ010000059 DACCVZ010000000
VERSION     DACCVZ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17379
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.059"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(82..627)
                     /locus_tag="IVW63_001968"
     CDS             complement(82..627)
                     /locus_tag="IVW63_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP7860237.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(639..1331)
                     /locus_tag="IVW63_001969"
     CDS             complement(639..1331)
                     /locus_tag="IVW63_001969"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAP7860238.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1350..1634)
                     /locus_tag="IVW63_001970"
     CDS             complement(1350..1634)
                     /locus_tag="IVW63_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860239.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1647..2210)
                     /locus_tag="IVW63_001971"
     CDS             complement(1647..2210)
                     /locus_tag="IVW63_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAP7860240.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2438..3100
                     /locus_tag="IVW63_001972"
     CDS             2438..3100
                     /locus_tag="IVW63_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     protein"
                     /protein_id="HAP7860241.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3224..4420
                     /locus_tag="IVW63_001973"
     CDS             3224..4420
                     /locus_tag="IVW63_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAP7860242.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4521..5897)
                     /locus_tag="IVW63_001974"
     CDS             complement(4521..5897)
                     /locus_tag="IVW63_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7860243.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5934..6800)
                     /locus_tag="IVW63_001975"
     CDS             complement(5934..6800)
                     /locus_tag="IVW63_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HAP7860244.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6889..7914)
                     /locus_tag="IVW63_001976"
     CDS             complement(6889..7914)
                     /locus_tag="IVW63_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7860245.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7932..8606)
                     /locus_tag="IVW63_001977"
     CDS             complement(7932..8606)
                     /locus_tag="IVW63_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7860246.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8790..9683)
                     /locus_tag="IVW63_001978"
     CDS             complement(8790..9683)
                     /locus_tag="IVW63_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP7860247.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9757..11454)
                     /locus_tag="IVW63_001979"
     CDS             complement(9757..11454)
                     /locus_tag="IVW63_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP7860248.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11447..12760)
                     /locus_tag="IVW63_001980"
     CDS             complement(11447..12760)
                     /locus_tag="IVW63_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP7860249.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12760..16797)
                     /locus_tag="IVW63_001981"
     CDS             complement(12760..16797)
                     /locus_tag="IVW63_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAP7860250.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16810..17268)
                     /locus_tag="IVW63_001982"
     CDS             complement(16810..17268)
                     /locus_tag="IVW63_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP7860251.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
BASE COUNT         4871 a         3903 c         3018 g         5587 t
ORIGIN      
        1 agagcataaa acaaagtcgt ttgttttatg ctcttctttt attattttgt gctttttatt
       61 ttatcaaatc actttgtttt tttataaaat ttctgcgcct agtgtggact caaaatgtct
      121 caatgcccat tcatgtccaa cgggatcgaa acttgccacg gaatctttga aaatatggag
      181 tttgtatcct agattatacg catcgactgc tgtatgcaac acacagatat ctgtacatac
      241 gccggtcaaa taaatatctg tgatctggcg ttctcgcaaa cggatgtcta gatctgttcc
      301 actaaaagcg gaataatgcc gtttgtctat ccaataaaca ttttcctctt gctcatagtc
      361 ttggtataaa ctttttaaag agccgtacaa ttcccgtcca cccgttccta tcacattatg
      421 cggaggaaat aagcggttct ccggatgaaa ggaatctttt ggatcatgcg catcaatggc
      481 aaaaacgaca aaatcctttt gatcaataaa cttctttgta tgagcagtca gctttttttc
      541 aattacttgt cctgctgtcc cagtagtcag ctttccatcc tctgcaacaa aatcatatgt
      601 gtagtcaatc gagatcaatg cgttcatctt agtcctcctt atacgagatg tttgacaaat
      661 tcgatcacca tttctgctga tcgtttgcct gcgtcttcga taaattcgtc aaagctttgt
      721 gtcgccgagt gatctgctgt gtcgctcatt gcacgtacga tcaaaaatgg gatattgaac
      781 tgacgagctg tttgtccaac agcggctcct tccatttcgc aagctaatgc ttcagggaaa
      841 ttcgttaaga tttctttgat tttatctggc gagtcgacaa atgtatcacc tgtaacgatc
      901 aatccttctt ttgcgttcaa attcgttgct tttgctgctt taaccatttc actgcgcaaa
      961 tatgtgcttg cttcataata tagaggcatt cctggtaatt gtcctgggtt gtagccaaat
     1021 cctgttgcat ctgcatcaaa ataagctact ttgtctgata taacgatgtc acctacttgt
     1081 aagccttcac cgattccgcc agctgaacct gtattgatca ccatgttcac gccgtattgt
     1141 tggatcaaca gacttgtggt aatagatgct aagacttttc ctataccgga acgtacgacg
     1201 atcacttcgt ggttacctaa tgaacctgaa ataaataaag cgcctgcgcg ttcccatgat
     1261 aatggttcgc ttaggttctc tctcaaaatt tttacttctt cttccattgc gccgataata
     1321 ccgattttca tctttttaat tccttctttc tatataaatg cgattgctaa aaaaaccaca
     1381 cataacatta ggataacaat aataagagat ttcatcaaaa aagagttcca tttggtcgtc
     1441 ttttcccgtt cgctgatcct tgttttcgtg attggtttat tctttttgct ttctttacga
     1501 taaaagctgg caatcttttt ttcttcttgc tgataagctg tttctgcttt tcgctgtttt
     1561 tttaatgact cgcttgcttg tgcttgttgt cgcttgcgaa gttcgcttcg cgtaataagc
     1621 ggtcctttgg ccataagccg atccctctac tttcctttgg tcaatagttc ccagtattga
     1681 atcgcataaa tcgtctttgc atcacaaatc aactgatctt tcatcgcttg ttgcgcctct
     1741 tcaagagtta gatgatacaa ctccagtact tcgtcttcat cttgtgctaa aggattctcg
     1801 accttctcta ccccttgtgc atgataaata tgaaggactt catttgcaaa acctggtgaa
     1861 agatacatcg aagtaagatg gctcagcgac ttcgcacgat agccagtttc ttcttctaat
     1921 tctctagctg ctgtcatttc gggattttgt ccttctcctg gatcgatttt tccagctgga
     1981 atctccaaaa tcactttttc taaaggtttt cgaaattgtt tgacaagaag cagacgatct
     2041 tgttcgtcaa aagcaatgat cccgacaccg ccaggatgaa ataccagttc tctcttcgaa
     2101 gttcctccat ctggcaaacg aacttcgtct acagcaacat caataatttt tccgctatag
     2161 atttctttgc gactgattgt tttttcttca aattgctcat tgttcagcat atcttctcct
     2221 gctttctttg taatcataac tgcttttttt tcatttttca atttttctca aaaactcctt
     2281 attagtttac catagataaa ccttagattt tctctaaata tagaaaatcc ttctttagtc
     2341 cgatactctt tctagtagtc cgtatgctaa aataagtatg taatcgaata acgaaaagaa
     2401 ttcaatactc aacgataaat gacatggagg gtttattatg ataaaacgaa attggccgtg
     2461 gcttctagca ttggtcttgc tatttctctt tgtccgaaac aatagttttt cttttgttct
     2521 aggactttta ttgataggtg tagttttagt tttgtgggga ctctttggtt cgcgcaggaa
     2581 aaagggaaaa caagaagaaa ttcctgcact gactgacgaa cttgaaactc actatgaaaa
     2641 aagcggtatg acagcgaatg aaatttcatt ttttcgacaa acaatgaatc aaacaaaaaa
     2701 tgagatcaat caattgcaaa tgaatatgca gcagacagcc aaacttaaag caatcgatct
     2761 ccgccatgat ccagtcaaag cagcgaaagc tttattcaaa gaattggtga aagaaccaaa
     2821 ccgactgcat gaagcaagtc agtttcttta tacgcatctg ccgaatctag ttgatttgac
     2881 aaataagtat aatgagatca atgaccatga gatcaaaaac aaacagacct atgaaaaact
     2941 agaagaaagc gcgcagatca tcgaccagct gtcagcttta atcgcacaag attatcaaaa
     3001 attcgttgct gaggatctag atgatatcga cgtagagata tctgttgcga aacagagctt
     3061 aaagcgtgat aataaatatg aaccagaaca aaaggattaa ctcttttgtt cataaaagaa
     3121 gactcggaac attcagatga tgtctggctg tttcgagtac tttttctaaa gtagagacat
     3181 tcatgtaaga atcgagaaca gattcaacaa ggaggaattt tttatggatc ataaaccgac
     3241 tgaaacaaaa gatgttacac cagttaacga tacacttgaa gatttattga acaacccgtt
     3301 ttcaactcca acagatacgc tgaccacttc acaacaagcg gagattgatc agctccaaga
     3361 gcaacagaca gctgctcgtt taattgacaa actaccggcg gaacgccaag aacaagctaa
     3421 acagctagca gcaaaaatcg atgctaatga tgcacagtct gtcatcagct acggatcggc
     3481 tgcccaagca aaattaagtg aattctcaca atcgatgttg aatcatgtgc aagcacaaga
     3541 tattggtcct gtaggagatt ccttaactga actgatgtat cgtctccaag aagccaatcc
     3601 tgacgaactg cgtgccggag aagggaacat cttccagcgt gtcttcggga aggtcaaaca
     3661 atcgatctat gaagtgacag caaaatatca aaagattggt gcacaaattg acaagatttc
     3721 agtgaaatta gataaagaaa aagacggtct gctaaaagat aatctgatgt tagaacagct
     3781 ttaccagaaa aacaaagact actttgatgc actgaatatt tatatcgctg ctggagaatt
     3841 gaaaatggaa gaacttcaaa caacgatcat tccagaagcg atgaaaagag cagaagaaac
     3901 tggcgatcag atggatgttc agattgccaa tgattacacg caattcctag atcgtctgga
     3961 taaacgtacg catgatcttc gcttagctag acagatcacg atccagcaag caccacaaat
     4021 ccgtttgatc caaaacacaa atcaggcctt ggctgaaaag atccaagcat ctatcgctac
     4081 agccattccg ctgtggaaaa accaagtcgt gatcgcattg accttgcttc gtcaaaaaga
     4141 tgcagtaact gctcaacgcc aagtctctga aacaacaaac gacttattga agaaaaattc
     4201 agaaatgctg aaaatctcag ccatcgaaac agcgaaagaa aatgaacgtg gaatcgtgga
     4261 tatcgagacc cttcaaacca ctcaaaatga tttgatcgaa acaatccaag agacattgcg
     4321 tatccaaaaa gaaggaaaag aaaaacgtcg tcatgcagaa gtagagcttg gacacatgga
     4381 agaagatctg aaacaaaaac tgttggattt aacccaatag atcacctttc gcttgttact
     4441 aaaacaaacg cccaacaaca gtttattaca actgttgatg ggcgtttttc ttatctttct
     4501 tctaacttct ccattggagt ctatttctca ttcatcttgc tgtgtccata gccatagcca
     4561 aaataaatga tcagtccaat aaccattacg ataccgaaca cgatccatgt cacagtttgc
     4621 agacgaagca tcaatacaat acaagtcaaa atggagacga ttggcaatag cggaacgaat
     4681 ggcactttga attctccagc ttttggtttg ccaaacattt ttctcaactt cagtaagcct
     4741 agactaacaa gcatcaaata ggcgagcgcc atgatattcg ttagttccgc taatacattc
     4801 aatgggaaaa atccggcaaa gaatacagct gccacaccag cggcataagt cgcttttttc
     4861 ggtgtacgat gcttttgatc gatttctgtc ataaacttag gaagtaagcc atccttgctg
     4921 acagcaaaca gtaaacgagc aagtgaatac atcatcgaga tcgttaccgt cagtagcgtt
     4981 aaaattgccc ctacagcgat caccgcgccc actgttccat gtcctacata cctcattgca
     5041 aaagccactg ggtcattgac tcctagttca gtatacggaa cgattcctgt caagatcagc
     5101 gtcacgatga tgtaaaggac agtagcaatc agtatcgaac caatgattcc tcttggcaca
     5161 tctttttgcg ggtttttgac ttcctcggct gccattgcaa cggcatcaaa tcccaagaaa
     5221 gcaaaaaaca caagagctgc accatctagc acaccggaaa aaccaaaagg catgaatggc
     5281 tgccagttat caggtttaac gaaaaatatt cctacaatga taaacaacgc gatgatacca
     5341 aatttgacat ataccatggc attattcaaa cgtaatgctt tcttggcttc aagcgacacg
     5401 atgtaagtga cgaatatcac tacgagcacc gcaatcaagt caatgtatgt accattttcc
     5461 ggattgtacc cgccagttaa tgcttgtgga agttcggccc ctaaactttt caaaaaacct
     5521 tgcatatagc cagaccatcc ggaagcaaca gaggaaaccg ctagtaaaaa ttccccgatc
     5581 aacaaccacc ctgtcagcca ggcagcaaat tcaccaaata caacatacag ataggcatat
     5641 ggcccaccaa tcactggcac tcgcgaagca aattctgcga aacttagtcc agacaaaatg
     5701 acaacgattg cagctaagac aaatgaaagt gacagtgctg gaccagcatt ttgattggcc
     5761 gcaacccctg tcaccacaaa tattcccgta ccgatgatcg caccaattcc aagcatgatc
     5821 aaatcagacg tttttagttc ttttttcatc tcactcgtat gattgagatt gatctctttc
     5881 ttacgaaaca aatccattga agttcctccc cattttaggt tggaaaacag cgattaaact
     5941 gttttcatat accctaaaag gataccacct aaaatgacta aaaggcaacc aacaataaca
     6001 taaatgagct cttttttcgt ttttctttcg ccaaggatga aaatcccacc taaagtagag
     6061 ataatgatcc ccatttgtga aagtgagaag ccaacagcta aaccaagtga tttgactgtt
     6121 agaagcatgc agatgtttcc taagccccat aataatccac agatcatgtt tttccacaca
     6181 aactgatcga ctttaacttt acggaaagca aagaagcttg cgcctaagat cattccgata
     6241 ctttgaggta agataattga catcgcatcc aaattcgccc agttgacgat gatggtatat
     6301 acaccataac caatcgtaga gaagatcaat gctctaaaac ccttaccaaa atcaagcatt
     6361 ttattatctg tatctatttt tccttcgtca tcttgtcggg cagtcaaata cgcaccgctt
     6421 acaagaagag ctaaagcaat aataccgtat acataatctt tcgtttgtgt ccattcatgg
     6481 aagaaaacgg ctcccgcaat cgtattcaaa attaattgaa aaccagtaga caatggtagc
     6541 cctacagaaa cacccatgta cttcattcca tggaactgtc cattttgtcc aacactccaa
     6601 gctaagccgg ataaaaatcc gatcaagaaa atccaagggg tgattacagg actaacaacg
     6661 aaaaagacaa ctaaagaaaa cagaaatgca ccgatcgtca ttcctagtgt ttgttgattg
     6721 gcatcgccac caattttacc acttactaaa ccaatactac cccatgccaa catagggact
     6781 aatgctatta aaatttccat aaccaatctc cttttatttc acatgataag aaacttatca
     6841 gcgaaaacgt taacaacaca agcacttttt ttcgtttcta acgattttct aacgtttttc
     6901 attataaaaa tttaagattg ggaaaaataa agtcattgtt gtcccttttc cttcagttga
     6961 ttcagccgtc aaatggatac ctaatttttc ggccagattt tttgctaaat aaagtcctaa
     7021 tcctgttgaa tgtgttttgc taagtcgacc atttctccca gtaaatccct tatcaaagat
     7081 ccgtttcaag tcttccgctg ggataccgat ccctgaatct ttaactgaaa ggctgactcc
     7141 ttgcgcttcc ttttctatgc tcacaatgat gtttccgtga tccggcgtat atttgatggc
     7201 attactaagc aattggttga agataaaagc gatccattta gcatcggtca aaacagtatg
     7261 atcctcacca acgatctcgt agcgaatatt tttttggata aaataatttg cctgactgcg
     7321 tatcacaggc tgaatgattc cttttagtcc atattcttgg atgaggtagt cccgcgagaa
     7381 actgtcgagt cttgcataat acaaaacttg ttctacgtat tcatcgattt ttgataattc
     7441 attttctagt aatgtatact tttgatcgtc aatatcgaac tcgatcgaac gaactagcaa
     7501 tttagaagcg gaaagtggca ctttgatttc atggacccat gagtcaatat aatctttttg
     7561 gtcttgttga ttactgattg ctgattgcat tacttcttgg tgttcacgga tcagctgatt
     7621 gatatattct tctaccagtt tttcttcttc tgtcctccca ccactcaaat aattttgcaa
     7681 aggggaagtt ttttgtatgt cggctaattt tccccaccat cttctcttgc tcaagtaacc
     7741 acccagcaga taaaaaatca gaaagacgcc ctcaatcaaa gctaaataag caattgtgct
     7801 caaatcaact ttgatgtttg gcgccagcca catcacaaag atcgtcaatg caataaaaaa
     7861 cagccatccc aagatcaatg tccactgatc tttcaaatat ttaaaaaaat tcatcttaac
     7921 cgctcatcct ttcagggaac gatatatccc tgtcctactt ttgtttcgat atatccttgg
     7981 atacctgcct gttcgatttt tcggcgtaac cgattgatgt tgactgtcaa tgtattgtca
     8041 tctacaaatc gttcgtcatc ccacagtgct cgcagcaatt tttcccgact taagatcttt
     8101 ccattgtgct tcatcaaaat aaataataga cgatattcat ttttgctcaa atcaatgatc
     8161 tctccgttga tttccatact tccgttgtca acattcaacg taatgccatt gtggctcatc
     8221 atttcactag ataattctgt gtagttgtaa gaacggcgaa gtaatgcatt gatttttgca
     8281 atcagtacat cgatttggaa atgttttgtc acaaaatcat ctgcccccat gttcatagcc
     8341 atgatcatat ccatattcgt attcctgctg gagataaaaa tgatcggtac tttcgatact
     8401 tcacgtattt tttgacacca ataatagcca tccaaaacgg gaagattaat atctagtaat
     8461 acaagctgtg gttcttctct ttcaaagtct gagaacactt gattgaaatc ggtcgttcca
     8521 aaggtttcaa attgccattt ctcaagttcc tccatgatca attgtcgaat gatctcttcg
     8581 tcttcgacta ccatgatttt tgccataaaa aatccctcca tctttcttct tgctactaca
     8641 atatcaaaga agcccttgtg aaacaagttg gcttacctgg aaaatgtcat tttagcaaac
     8701 gttaaaaaaa actggaaata tgcgatttaa tcgcgtttgt ctcttccaag cagcttaaat
     8761 ttattatgtt attcttaata attggtctat tatctgttat ttttctttcg ttgtttttgt
     8821 cttttaaatt ttcgataaca ccaataaccg aaaagcgtta gcactagcaa tatacctaga
     8881 aggagtataa gtaatcgata aagatggtat ttttttgtct gttctatctt tgaagagact
     8941 tcttctgtaa agggaactcg tcttcctgtc actagtaatc ggtgagtgtt cacggtgtaa
     9001 ggtgtacaag tgataagtgt gactagatcc tgcttttctc taattgctaa tgtatttgtt
     9061 tttgttggaa ggacaacaat tttctcaacg acttcataag cgagcatccg accatacact
     9121 tcaagataga atcggtcatc ttgctccatt tcttcaagat ccgtaaagag ttttttctca
     9181 gcaataccgc tatgggcggt aatcacggaa tgtgtactct ctcctccagt tggaaaagag
     9241 gtgccttgca ggactgtcgc tcctctatct aacaaaagat cattcgtttc atcaaataaa
     9301 ggcaagctaa cattgatttt cggaatatag atggctccga tcatatgttg ttcgtaatat
     9361 tcttttcctg gattttggac atttctaacc gcttgctcaa aaggatcttt gacttgtccc
     9421 attcctggga ttactgatgt atgagcaagc gtctgatttt tcttttcatg cactgctaat
     9481 tgttgctcat gtttttcttc tttatcgcgt tcaagctgct tttgataatt ctcgatcctt
     9541 ctttgatcca aataattgct gagagcatct gctaaaaatg gatatgtaaa aactgcagct
     9601 ccggcaagaa acatcactgc cataaataat tgtaataaaa gactgatttg ggtttgaggt
     9661 ctattaccta ttttcttttt cattttcttc accttcttat ttaaaaaaac tgcagcaacc
     9721 tttataaaac cgattgctgc agcttatttt tgttgcttat acttcagact tcattttaga
     9781 tttacggtac cagctgtacg ctccaatcat caaacttatt ccgattagta agaatgccaa
     9841 gagcccgttc ccaccagtag caggaagtga cccgcgtttc atattcggta ctctttctgg
     9901 ccctggattt tctactccta cgatctgaat ttcttcatta tagcttccat aagagatgat
     9961 aaattcagta aaggctgcct cacctgttgg aagtacataa ccttctggcg ccatggtctc
    10021 tttcatttga taggttccat aatctaaccc ttgaacctca aagtatccat ttccatctgc
    10081 gacaaattct gttgcttgtc cgcttgttgc ccactcaatt ctatctgctc ctgattcata
    10141 aacagctaaa ggcgactccc ctttataaaa tattgcgtat tcagaacggt cttcattcca
    10201 caattcgaat cttgcatctt taagcaattc actgcttgat gcatcatatt tttcaaactt
    10261 tcttccacct gttgtgactt tctctggcgg ctctactcct tcttcataat caaattcatc
    10321 atttcgtccg atttcaataa ccgctgtgtt gttatggaaa tcatccgctt ctagttctgt
    10381 ggaaaccttc aaattatacg tgatcgttaa atctcctcca cgtgcatctg ctaatctacc
    10441 taaagtatct actttggcta ctccattttc ttctgtcaaa atcgtcacga caaacccgtt
    10501 gcttactact tctactatat aatcttgtcc ttttgttaaa atcgtctcgc cggctcgcac
    10561 ttctatttcc tgatcataat aagttagacc aactgtaggc gtatctgtga ttttgtaatt
    10621 tttgataaca gcgcttccgt tttcaaggac agaatcgatg aaataaggaa taggtgctgt
    10681 gatcgtgtaa gaagccgttt ttcctctttc tagatcaata taagaaatcg tttcttgttc
    10741 tccagcttca ttaataatcg ttacttgtct aaggtcgctt tcctctacat tcatctgttt
    10801 atctgcttct ctgatttcgt ttttcggata caaatgcaca tctgtattgt atgtgtcttt
    10861 ccatgtagaa ccatcccaca cgccatccac catatcaggc atcatcactg gcatcataac
    10921 aaccattgga gacgcgattc tggaaatatg agctggcgaa taagtttcta agaaaagata
    10981 gactttatct ctagaagaag gtgcttcttc cgtcacttgg acggtagaga ataccgcttc
    11041 tccagcttca ttcgttgttt gtttgtcaat acttgtcagt cgatatttta aaaaccaact
    11101 ttctgtgtgc cgtttttgaa tccattcaat cgcttcggca gaattaagac cgtcttctcg
    11161 ttccggtgtt aaaggattat ctcgaatcaa atcgtaatat acttccgtta cgtcaaacaa
    11221 atcaaaatcg actcctggaa tattttcttc accaaaatcc gtagaaacca atccgctatt
    11281 cggtcgttct tccggaacag atgagaaacc ttttttgtgt aatgtaatcg tcacttcact
    11341 tggtttttgt gcgacttctt cggctttgac tagttttccg ttcccgaaaa tccctattcc
    11401 cgcagtaacg agtaacagta cactcattcc cgtgacaatc atttttttat tcattttttt
    11461 ctccccgttc tttttttatt aataaaacag cacctaacaa taaaagaatt cctagtaaag
    11521 aaatcaacgt tcttgcttca ttcgtttgcg ggaatacgga ccattttcct gattgacctg
    11581 gattgcttgg accactcggc tctttcggtt tgtccgttgt ttcttttacg gtctcgttat
    11641 aaacacgtgg tgttgcggat tcataggcag agactggaac tttcccggat tctaattcag
    11701 ccatctcctg tccgttaact actacatatt gtggttggcc ttttgcatcc acccaaaatt
    11761 cagggatgat gacctcgatt ctcttacttg cttcatccat ctcgtaacct tccacacctt
    11821 ttaattcttc aaaataatag gtgccagaag gcaagaaacg ttgtcctgtc gtaacaaggc
    11881 cctctttatc cgaaatgaat ttgcttacat ttttgtcatt caaaggatca ttgtctgctg
    11941 gtttgatcca ttgatttttc aagtcattag caggagccat atctaaataa tatttccccc
    12001 cttctatcat ctgatataga gcaaaaacag caccttctaa tggttttcct ttttcagttg
    12061 ttcctctttg acgtccatac ttgaagaagt atggatctct tagataaccg acatttttag
    12121 gatagatatg aatctcttgc agttcctcgg ttgattctgt cgggtgataa attggcaaaa
    12181 tagcagcaat tgggatagct gtctgatcga tatcaacatc caatccaact tctggatcaa
    12241 tcgattcttc gaaaatcaaa taaactgcat cccgatcttg gtttttctta ggtgctttga
    12301 tacgtgcaat cccgtctcct aatccgccaa ccgtatcttt cccagttgtt accgaagtcc
    12361 ctatttggac aagcctttct tctgtgatta gctgacggat attgtttctg ttcgtttcag
    12421 cgatttgctg gacgaattct ttaggagtca tgttttcagc agcttttttt tcatgataat
    12481 aatcggtcat gtcgtaaatg gcaaatgtcg ctccatttag tggcaccgtc tgtgaaatga
    12541 tatctgctgt ttcccctgct tcctcagaga tagccaagcc atcattttca tggtattcaa
    12601 attgatcgtt ataatcgata tctcgaatca tccgtttatg caacacgaat tccacgacat
    12661 cttcccctga ttcttctgcc gacatcgcat gtggaagaag gactgctgca agcggtagta
    12721 aaacaagtaa ttgaagcatc aaacacaaca gctttttcat taccttgctc cctccttttt
    12781 agattgtctg acaaacaaac cataggctgc tcctgcaagc gccatgaaga atgcagcaag
    12841 caggatatag aataatcgtc cggatcctcc tgtagcaggc aacggatttt caggatcgtt
    12901 cccgacacta agctgtaatc tgattcgatt tgtctccaaa agttcatatt ctaactcttg
    12961 ctgtagatca ggcgtctctg cttcttcgtt tggataatac gaaatctcaa cttttagtgt
    13021 acccgcttct tttcctggaa ctacccgatc attttctatg tcaggttctt ctcgataact
    13081 aatttctaaa ataaagtaac ctggaagttt tctatagctg tcaggtgact tcacttcctt
    13141 gatccgatag accccttcca acaagtctga agcattgaat agggaagaat cgtttggatc
    13201 tggtgccaag cctccctcga tgatttcata ctctcctgca ctattttgtt tctcaattga
    13261 aaattctgcg ccttcaagac gtcggctatt catactgtca attttcaaaa gttccaaatc
    13321 gattggcgct agttcatctt ctaaggttac ttgtagtaca ccatcgatga tttcatagcc
    13381 ttccggcaag ggagcagttt cgtcttcgat gaccgtatct tcaatgataa acttaccttc
    13441 ttcattcagt gcaaactgga acacttgatc agatagccga tacccatttg gtgcgacaga
    13501 ttccgagacc tcatattcac caatagacag atgcagaggt tggtcgtaat ttaaatcgac
    13561 atacttttct actcctacgg cacgagaata gaagtatccg atcccaggca aacgtttcga
    13621 ttcttctggt tctaacggat taccagtgta tgctcgatac agcgggaagg aagaatcccc
    13681 cactttcctg atatcgaaac ctgcaccatc taatgtatgg ccttcatggt ctaattttct
    13741 aactcggatc tcccgataat caaacgtatt gtaagcagtg aatgctaccc ataaacgatc
    13801 ctcttcatct gttgtatacg tgagatattg ccaattttct tcacctgttt gcttgagttg
    13861 gatagtccct atagcattat cgtaaagtcg caagatccat gtgtcatttt catcaggttc
    13921 tttgaaacct tctgggttct ggctctcaat gattttgtat tctgcatagt tggtagtttc
    13981 ttcactatcc ttataaacaa atgaatctgg ctctccgatt ggatgaataa ctttctcacc
    14041 atccacgatt acatatttcc cgtcttcatc tactgaatag aacgtgagtc tccctttctc
    14101 ttcctctact tcgttcacac cagaaagccc tttcgctact ggatatccga tttccagtcc
    14161 gttaccatct gtttcataaa gttcaaactc tgcgccattg attggcatat tactgccttc
    14221 aattagttta ttgatattca tgtggattgg cttgaattca tttcgcattt ccagtttgac
    14281 atacaactca tcatactctg tgccttctat gttaggctct tgtacaacag aaagcttgtg
    14341 atattctcct tcataatagg aattcggatc tttaccttcc ggtccgccga ctctcgaacc
    14401 agatgtatat tcatctacaa gctcgtagtg acctaacatc tcatcttcgt tggctgcata
    14461 ttttttgatt tggaattgat acgtctcatc tactaactga taacgtggtg gtccagcgat
    14521 ctctctgatc caaaatatgt cgctgactgc tccagtttca tctcctaaaa tcggcatctt
    14581 cgtttcaaag atcgctattc cgtccgtggt agttttactt gtttcgattg gttcggcttc
    14641 cccactctct ggattttggt catataatgc aaattcgact ccagccaacg gctcgccatt
    14701 ttgacccttc ttgctgactt ggaaattacg gcctttatgt tcgtaacgaa tggaagaaga
    14761 tgggaaatac atccgtccag tagtgatatc attctcataa tcctccaggt tctgaatata
    14821 ggccatattg ttcactgtgc aaaaatttcc gtcttgagct cccgcatcaa gttttacttg
    14881 gtacttgatc ctgaccattt ccccttcacc taaagaaatc ggagaaaatt tataagcttg
    14941 gttttcccgt ccgacatacg ttgtcggagt cgccactact tctggtgggg cttgtccatg
    15001 acgttcttca tcccatattt ctggctcttg gtacttcatg ccgttttctc ctggatctag
    15061 atggtaaaac tgaatatctg ccgatctgcc agctccaaat ggtgagacat taaaaccagt
    15121 ttcatcataa agtgtggctt gctggatcgt tctcttgaag gtagaagaga tatcctccaa
    15181 ggctgtaaca atgtcattct tgttgttcgc attgtaatat cgcggtgtta cgccatcttc
    15241 ttctaaatca gcaatatttt tcaatacatt tcgtccaata gcatctagtc gttgtctccc
    15301 gctaacgttt ccatcgattc ctaaaccaat ggagaagata cttggcgggt tctcttgata
    15361 cttgtttttc agccaatgat gataagcaac tgtgttgatc gcagatgact tttcttgcga
    15421 agtaggactg ccattcgtat tgttattaga agaaccatca ccaacccagt gagtcgcttt
    15481 attatctcct tcttttacct ctccataacg atagtgtaca tttacttcat cttctggacg
    15541 gttaaagtca gatgcatagg taactggatg agtaaaccct gcattagaag tattcccaga
    15601 aaactcctca aaatttctga acaaaacgtc attatcttca gcaatcttat cttccatcac
    15661 agtccagttg ctccaagctc cattagtgct cgtacgataa cttgactgaa tcggtgcata
    15721 actgaaggtc ggtgtcccat ctcccacaac gattaggatt ttttctggat ttctattttc
    15781 tccgccattg tctttataca atgtttcata gccattttta agccctagtg taagcggagt
    15841 tcctccgatt ggtgtacgat ttaatgctgt attctcactt cccgtcaaac gattgatatc
    15901 atttgtcaat ggaaagatgt ccgaactgat ttgctcatgg ttattgatag ctgtactatt
    15961 atggtaaaaa ttcaccatac cgattcgaat atccagactc gggtcagaga gcagatcttt
    16021 actcatttcg tttactgcct caatcaacgc agcattttta gtttgactat tggtcccagc
    16081 ggttaattca ctcatactcg ctgacttatc tagaacaaaa acgatatcga ttggactgat
    16141 ttcctttttc tcgcccccga tgacatctag atagacattg taaagggttg ttgcatcttc
    16201 aggatgtaga tcagatgctg tgctgcttgg cagaacaggt tctacccatt ttttgatgta
    16261 cgccccgtta taatccaagt aactgttttc aaaattccgt tcatttcccc aaagctgaac
    16321 ggtttgagct ggaacgtttc tatcttcttc gcctgcagtt gatccattat tagtagcata
    16381 gtcgtaattt cgccagttcg ctcccccgtt tgtataatca ctatcatcga tcaagttctc
    16441 tccgtcatat ggcgagcctt tgtctccttg atagcgttca ttgctttgtg tccaatttcc
    16501 taacactttt gtatagtcat tcgttgtaaa cttcgggtag cgatgctgtt cgttttcaac
    16561 ttctccgcta ggatagatat attcataggg gtcttgcgta gctgttggcc caagacgctc
    16621 caaaataccg ttgaataact ggcgttgaat gcgctggagt gcttgaccgc tgggtacgat
    16681 tggttcgtcc agcttttcca tctcattttc ttcgctacgt tgaatttcag cggaatcttc
    16741 tgtatcagtt tcattttctt gtaattcttg gttatctatt ctttcatcaa ccaccacttg
    16801 aagaggtagt tacccttcgt tcacatcggg gatcttttct gtttcaaaaa tcaatgtgcc
    16861 ggtttctgct tcttttgaat aaacttttcc gacataccat tcttgaccat cgatcgtctc
    16921 gacttttagg tcttctccat cttcatcata ggaggataga cctgttccac gaacgttttt
    16981 tacggtacca atcccggcgg ctgccgcatc gattgctaaa cgtattctac cttcattggc
    17041 actttccttt ttttcaaaag ccagatgcca ttcaagggtt tcttcttttt caatatactt
    17101 cccttcaatt tttgcatagt cctcatctaa gaatacctca tcctcctttg tttctgttga
    17161 ctcagcagct acatccaggg tcgtcatatg atagactgac tggaaatatg gtccaaatag
    17221 caaactgaca gttactaact gcaaaagctt caattttaac cctttcacat ccttatactc
    17281 ctttcaaaaa tatttgtctt ctttcacaac aatcaacaaa acaatgccca tctaattata
    17341 atttaattta actttaattt taaatcaaat gatatcctt
//
LOCUS       DACCVZ010000060        17264 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.060, whole genome shotgun sequence.
ACCESSION   DACCVZ010000060 DACCVZ010000000
VERSION     DACCVZ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.060"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            126..1466
                     /locus_tag="IVW63_001983"
     CDS             126..1466
                     /locus_tag="IVW63_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7860252.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            1684..2127
                     /locus_tag="IVW63_001984"
     CDS             1684..2127
                     /locus_tag="IVW63_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAP7860253.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(2631..4049)
                     /gene="nhaC"
                     /locus_tag="IVW63_001985"
     CDS             complement(2631..4049)
                     /gene="nhaC"
                     /locus_tag="IVW63_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAP7860254.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(4452..5675)
                     /locus_tag="IVW63_001986"
     CDS             complement(4452..5675)
                     /locus_tag="IVW63_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAP7860255.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(5706..6545)
                     /locus_tag="IVW63_001987"
     CDS             complement(5706..6545)
                     /locus_tag="IVW63_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAP7860256.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(6562..7242)
                     /locus_tag="IVW63_001988"
     CDS             complement(6562..7242)
                     /locus_tag="IVW63_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7860257.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(7244..8317)
                     /locus_tag="IVW63_001989"
     CDS             complement(7244..8317)
                     /locus_tag="IVW63_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7860258.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     gene            complement(8964..9635)
                     /locus_tag="IVW63_001990"
     CDS             complement(8964..9635)
                     /locus_tag="IVW63_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP7860259.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(9722..12400)
                     /gene="mgtA"
                     /locus_tag="IVW63_001991"
     CDS             complement(9722..12400)
                     /gene="mgtA"
                     /locus_tag="IVW63_001991"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAP7860260.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            13059..13496
                     /gene="ndk"
                     /locus_tag="IVW63_001992"
     CDS             13059..13496
                     /gene="ndk"
                     /locus_tag="IVW63_001992"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAP7860261.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(13518..14384)
                     /locus_tag="IVW63_001993"
     CDS             complement(13518..14384)
                     /locus_tag="IVW63_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7860262.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(14544..16637)
                     /locus_tag="IVW63_001994"
     CDS             complement(14544..16637)
                     /locus_tag="IVW63_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP7860263.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
BASE COUNT         4989 a         3572 c         3048 g         5655 t
ORIGIN      
        1 ttcgcctaaa agttttctga atagttgtaa ttgtctgaaa atttgttatc attagtcatt
       61 gttaaatatt gctatttatt cttaatataa attttgattg tgaatttaaa agaaagaggt
      121 catttatgga agataaaaaa ttgaaaaaac aacttagctc cagacatatc accatgttag
      181 ctttaggtgg agcaatcggt gcaggtctat ttaaaggaag tggcgaagcg attgggatcg
      241 ccggcccttc tgtattgatt gcttttttga ttggtgggct gattttatat atcgtgatga
      301 aaggtctggg aaaaatcgtt ttaagcggtg gcgacacgca tcacggatta tctggtttga
      361 tacgccctta tctaggtgct cattctgctg attttactga ttgggtctac tggtctatgt
      421 ggattatcaa tatcatcgct gaagctgttg cagctgcttc ctttttgcag ttgtggttcc
      481 cgcacattcc agcctgggta tttgttttta tgttggctgt tttaactacg atcatcaatc
      541 tttattcggt acggttattc gcagaaacag aatattggct ggcttttgct aaaatcagtg
      601 tcattatctt actgatcatt tttgctactt atcttgtcgg tcagcaaatg ttgggcacag
      661 gcgttttccc tacccttcag caattgactg accatggtgg gtttactcct catggtatga
      721 agggaatcat cagttctttg cttgtagtta tctattctta cggcggttct gaactgattg
      781 ctatcacggt aagcgaagca gatgatccta aacgtgcgat tcctaaagca atcaaaggtg
      841 tcatgggaag aatcatttcc ttttacatca ttcctttgtt tttgcttttg attctttttc
      901 cttggaatac tttagcaggc acgaatgtca gtccttttgt gatggtattt gaaaaaatga
      961 atatcccatt tgcagcggat atcgtcaatt ttgtgattgt ccttgctttg ttctcatcta
     1021 tcaattcggg tgtgtatgca tcttcaagaa ttttgttctt ccgtttgaag gatcgaaaag
     1081 gttcctctag aaaactagct gttttaaaca agcatcaagt accgcaacgt gctgttttat
     1141 tttgtaccag tgttctttat cttggtgtag ctctttctta ttttgtcggt gacaaattat
     1201 ttggctatct ggcaggttcc ctttcgtata cagtattatt gatctggatc attatcagtg
     1261 cggcatcctt tgtactggca ctaagaaaag gaacattatg ggataaagga atcagctttt
     1321 ttgcattagc tgtcttagga ttgattttcc ttggtatcct gttcacgaac tccattgggg
     1381 taactgtatt gactggcctg ctttacctgt tcatttattt cagttatcaa aaaaagaatg
     1441 atgcgttcgt attgacgaat gaatgaaatc gatagaaaat tttattttat ttatgtggaa
     1501 tagatggagc tattgaagaa aggagttgtg acaaaagtct tgttgcaact cctttttccg
     1561 aataaacagt ctcatgacct cttggtaaac ggtgttcaaa aaccctctgt gcaaaataat
     1621 tgattgttct ccatgctcat gacatgatag aagaaaggaa tgaaaaaaag gagtttgttt
     1681 taaatgaaaa agtattggaa gtttttgttg atgatcggtg tttcaacggt agttatgttt
     1741 ggtatgatgt acttgaatgt ctatgcgctc gatcatatct tcttcagtcg tacacgagta
     1801 ttcatggcgt tgatgatggg tgcagtcatg gcagtcatca tgctgttgtt catgtggaaa
     1861 atgtatgaaa acaaaaagat aaatgttatg atcttagccg ctagtcttct tgtttttgcc
     1921 ggttccttgt ttatggtacg aagccaaact actgtcaacg acacagcttg gatgaaggcc
     1981 atgattcctc atcattctat cgctatcctg gcaagtaaac gagctgattt aaaagatcct
     2041 gaagtaaaaa aattagcgga agaaatcatt caggcacaag aagaagagat cgacaaaatg
     2101 aaaaaaatga tcaaagaaat ggaatgacca ttatccgtcc aaataaaaaa agaggatgtt
     2161 ccagaagtta tcagcttcaa gaaataagaa gaagctactt ctggaacgcc gtgaataagg
     2221 ggttgtgaaa aagctgccct gcatcaagta ataagaacag ccaaacaaaa atagcttctc
     2281 ctatttttcg tttggttagg cttattaccg cagatgcaag cttttgaaca ccgtttatta
     2341 agaggttgta aaatcagcgt tctgacctga gtattagaga gacaaatgga aaaatagttc
     2401 ctcatatttt gccatttttt gagctaatac cgagggtcag ctgattgaac accgtttatc
     2461 gagaggttgt gaaaaagtcg cttagtttcg cgtattaaga aaaattttgt gaaatggctt
     2521 tccacatttt tgtataaatt tggcttaata ccgagaaact ggcttttgaa taccgtttat
     2581 tcgtaaaagg gattgtgaca aaagtcttgt cacaatccct ttttatgttt ttattgttct
     2641 aattgcgctg tcttgcttac tgcttcttgc ggtttcacaa atttttttga gattccccaa
     2701 cctgtgaagg cactgaccat cgaaaacaca ggagaaagca aactgaaaaa tacgaatggc
     2761 aagtaagtga gtgtaggaat accaaatgta cttgctacga aacttccggc aattccccaa
     2821 ggcactaagt agttgattac tgttccacca tcttctagcg ttctacctaa tacagttgga
     2881 tcaaatcctg ctttttcata agtttcttta aatgcattac caggcagaat aacagatagg
     2941 aattgttcac caataaaaat atttactccg atacttgtca tcaatgttgt aaaaatcaaa
     3001 tttggtgtgt tcgtcatctt tcttgatact cgttccatca cggttgagat caagccaaat
     3061 tcgatcaaca atccacctaa tgacaaagtt agaataatca atgacacagt aggcatcata
     3121 ctttcgattc ctccgcggct aagcagtgaa tcgatttgtt ggtttccagt atttgaaaca
     3181 aaccctgatt cgatgacccc agccaacttc gttaaggaag tttgtgggtt ttgaataaaa
     3241 atcattccta ctgctacagc gatattcaac aaaatcgtta aaattgccgg cacctttttc
     3301 catgcacaca gtaacattaa aaataaagga atcagtgacc agattgaaat agtaaagttt
     3361 gcttctagaa catcagtcac ttcacgaata gatgaaagac ttgcggcttt acttgtgtgt
     3421 cctaaaatca tgaataaaaa gaaagaaaca acaaatgccg ggacagttga ccacatcata
     3481 tgcttgatgt gtttgaacaa atcggcatca acaatagctg ctgctagatt tgttgattcg
     3541 gataatggag acatcttatc tccaaaaacg gcacctgaaa caatagctcc aacaaccagc
     3601 gctggattta agcctagtgt tgtcccaata ccgaaaaatg caatcccaat cgttgacata
     3661 acagtaaagg cactccctac agcgctacct acgattgcac acacaacaaa tacagaaggg
     3721 acaaaccact ggacactgat caatttgaac ccaatgacca ttagagttgg aatgatccct
     3781 gcttgtatcc atacagcaat caatgaaccg actaaaataa aaataaagat tgggatgatt
     3841 cctggtttga tgccattgat gattccttcg tgcagccaat ctgtcgggta tctttttatc
     3901 actgcataca acatgaccat tccgatcgct gctaagatcg tgatattagg tgagaccttt
     3961 aatccgacaa cgccaatcgc aatgcctaaa acaataacca ttaatacaag tgttgcttct
     4021 aaaaaacttg gtgttccttt ttttcccatg ataatctctc cttttttagt tgttcttatg
     4081 ttctaaaaaa gttaagatat cggattactc cgccgcaatt catccgcgat tcctccttta
     4141 taaaaataaa aagacctgtt ttaaactaag gacgaatgac tccgcggtac caccttaatt
     4201 aaaaacagat ctgtttttca ctttcaaact tttattcaaa tgtatggact ttccatgtaa
     4261 ttcgtcaatt aggcttgatc ggttcacagc gaccaccgac tttctgaaca aaacacctaa
     4321 ccgctactgc gtgaaaagtt gacttgtacg aagtttacct tccataagat catttgtcaa
     4381 tgaaaaagaa aatatttttt catttttctg aaaattattt ttataacttt cacacacaag
     4441 attatttttt actagaaagt agcgccctct tgtttttttc ttgctactat ttcttgatgt
     4501 tcttgcttga ttctttctaa tagctttggc tctttcaaca gatcaagagc tgtattggcg
     4561 agtagttctg ctgcaatcgc aatagaagca aggcctttgt cacttttagc agcagctttg
     4621 aattcttctg tgtgtccggc aatatatgtc tcagagattg ctaccgtagg ctggattgtt
     4681 ggtatgactt ggctgacatt tcctacatca gaagaaccga gacttgttct ttgttccgtt
     4741 tctatttctt catctggaac acctgcttct tttgcatgct ggaagaataa gtcatcaaaa
     4801 gaaggagtaa cgatgacatc atcaactgca ttttggaaca atccaaactc aaaagtcgtg
     4861 cccgtactta tcgcagcacc tcgtacgata ttttccactt tttcatatac tttatctaat
     4921 gtttgccgat ttcctgcacg taaatagaaa cgtccagcag cgtaatctgg aatgacgttg
     4981 gcagctactc ctccgtctgt aatgatccca tggatattga catcttttgg caattgcaag
     5041 cgtagagcgt tgattccatt aaacacttgg atcaatgctt ccaaagcatt tactcctttt
     5101 tcaggtgctg ctgctgcatg ggaagcgaca ccgtaaaatt tgatgtcgac tggatcattc
     5161 gctaaagatt ctgtcgtttt cccataacga aaagctggat ggacgcataa cgctacatcg
     5221 acatcctcaa aaaaaccttc tcgaacaaag ctgcctttag ctgatccgtt ctcgccccct
     5281 tcttcccctg gggtgccata tacacggatt tctccaccag tttcatcaat gaattgcttc
     5341 actatgctgg cggctaatac ggagtaagta ccaaacaaat tatgcccgca tgcatgacca
     5401 atacctggta aagcatcgaa ttctgccaaa aaggcaattg tgggaccggg tttattggaa
     5461 atataacgtg catcaaaggc tgttcggtgt ccagctactt ctttttctac ccaaaacctt
     5521 tctttttcta attgtttaat caacgctgct gaggaataaa actcatagtt acttacttca
     5581 ggatgttcgt ggatatctag agcaagtgct tgatattctg gtaaacgata ttggattaga
     5641 tccttcaatt ggtttgttga gattgttgtt gtcataaaaa attcctccta tgctagtcat
     5701 ttttcttatt ttctcccgaa tgtttcccat gcaggcacgc ttgatccttt tgatgttttc
     5761 tcgattactt tgactgtgtc ttctgtttga taagcgtcta ctattttttg atacgtttta
     5821 ttgttttcat cttcttttct tgcaacgatg atattcacat aaggacgtgc atggtcatcc
     5881 actggttcta agaagatggc atcagaagca ggattaaatc cagcatctac agctacaccg
     5941 ctattgatca ctgaaatgtc tacatctgac aaagcacgtg ctgtttggga agcatctaat
     6001 tcagaaatgt ctagattttt tctattctcg gtaatatcag aaacagtggg cgcttgtcct
     6061 tttgccttat ccactttgat caatccagca gtttgcaata acagaagagc tctgccgcca
     6121 tttgtaacat cattagggat tgctactttt gctccgtctt tgatatcagc tacatccttc
     6181 aaagtgttag aataaattcc cagcggtgca ttgacagtat ttccgatcga tactaaatca
     6241 gttccgtgtt ctttattgta attgtctaaa aagaattgat gttggaaaga attcaaatca
     6301 atcgatccat ctgctaaagc cacatttggt tgattgtaat ctgtaaattt cacgtattcc
     6361 aaattaatgt tctccttttt caaacggtct ttcacgttgt cccatacatc tgtatcttct
     6421 ccaataatcc ctagttttac gatagtttct tttttgtcag ttgtatctgc ttttccttgg
     6481 ctacaccctg ccaaccaaat aattgctaca aatgtaatga ctacaaaacg aataattttt
     6541 ttcatttttt ctcctccact ttcaatgtgt aattttttta atcagttgat tactgataaa
     6601 ttgacttaaa aaaactaaga ttagaatcaa taatgtagcc acaatcgtta catctgtttg
     6661 gaatcgatta taccctctcg atatagcaag attccctaat ccgcctgcac ctactgctcc
     6721 agccatggta gtcagtccga tcacgttgat gatagtcaac gccgagaccc gaatgatacc
     6781 aggcaaacct tctaacaaat acacacgtaa aatgataccg attggactgg ttcccatcgc
     6841 ttctgccgct tcgatcaccc caggatcaac ttctagcagt gcgttctcga tttgacgagc
     6901 aaaaaacgga acaactccaa aaatcaatgg cactaaagct gctttcgcac caatcgtcgt
     6961 tccaactaag aaacgagtag tcaatgctaa aagagaaagc aagataatga aagggatgga
     7021 acgaatgata ttgatcagct tatcaagtat ttcaaatagc agacggttag ctagtaatcc
     7081 attagggcgt gtcactacta acgtcacacc taagatgatt ccaatcatcc cgccaatgaa
     7141 tgctgtccaa aaagacatat atagtgtttg cttcgtcgct tcgacaaatt catccggaat
     7201 caaataaaca ttgggcaaat atgttttaaa gaaatcagtc attttatctt cctccttcga
     7261 tcactttgat acgactatct aaatcgtttt tttgtaaaat atttattttt acaccagatt
     7321 tgatcaaata atccaatgct tttttccgct gtttggtttc tccagctaaa gtaacgatca
     7381 aactccctaa cggcgtttct tgtaataact ctacattgcc atataaaata ttcgctgtta
     7441 cttgatattt gctgtacaga tgagcgatta gaggttcgtt cgtctgattt ccaatataac
     7501 ttaattccac tagccattta ttggcgatct gatcggcaaa agcagaatgg gcaatgatcg
     7561 tttctaatgc ttggtcaaga tgagtagctg ttcgaataaa atctttggtc aattcttctt
     7621 caggattgct gaagatctgg atgctgctac ctttttcaac gattcttcca tcttccataa
     7681 ccgctacctt gttgcagatt tctttgacaa cttgcatctc atgagtgatc aggacgattg
     7741 ttaaacctaa ctggcgattc aattttttta acaatgcaag gatctgaagg gtcgttttcg
     7801 gatcaagtgc actggttgct tcatcacata ataatacctt aggttcattc gccaaagctc
     7861 gtgcgattgc tactcgttgt ttttgtcccc ccgacagttg tttaggataa gcagatgctt
     7921 tttcttccaa accgacaagt tccagtagtt cattcacttt ttgacgacgt tcctgtttcg
     7981 attttccaga atactttaaa gaaaaatcaa cgttgtcaaa aatagttcgg ctttccatta
     8041 gattgaaatg ctgaaagatc ataccgatgg cctttctttc ttttcgcaat tctttgggag
     8101 agagctgact cagattcgtc tgattgacaa tgacttctcc tgctgttggt ttctgcagca
     8161 aattcatcac acgaactaac gtacttttcc ctgcacctga gtaaccgacg attccataaa
     8221 catcgccttt ttcaatcgtt aaatctacag aatctactgc ctgtatctct ttttcttttt
     8281 gtttgaaaca tacagaaaca tctcgcaatt caatcattaa aattcctcct tatctaaaaa
     8341 aagcgtcctc aagaaaatga aaatgtcatt ttcttgagga cgcttttttg cgtgttacca
     8401 cctcatgttc aagctgtgtt cacacacaac tcctcttcaa gtacgatcat actctagcaa
     8461 gatatcggtc gcagccgtca tcgccttaca tctatgctcg ggatgaattg ctcgatggcc
     8521 attttccaat agtcgttcct tgcttcttct cagctaccga agctctctgt caaaggttct
     8581 tctatcgtac ttaccatttc aatgcaaata atattcaaaa aaaaagtcct tttactaaca
     8641 taaactatgt cagtaaaagg acgacgtatc gcggtaccac cttttttcgg aagtttcctt
     8701 ccctcaagcc caacatctca aaaagagaga ttggcgttcg ttttaacggt cgaacagttc
     8761 cgaatttgcc tacttatcga caaattattc tccaaggcca ttttcagctt ttcttacttg
     8821 actcttctca ccagccagag cctctctgca aagtttccaa acttactttc cttttcaacg
     8881 aaatcgatat tttgttgttg ggattaatct acatgaggaa aactgaaaag tcaagtacga
     8941 aattcaaatt attttttcta tatttatttt tctgtttttt tatttaacat ttcaataaca
     9001 gttcgaagat cttttccttc cgcaagaagt ttcaattttt ccttttcttc gacggtataa
     9061 tttcggacaa aactggaatc aggtatcaaa acaacgccta atcctgctcg tgaagcagct
     9121 gttgctccta ctaaagaatc ttccactgca aaggctgaac tagcttctaa tcctgttcgt
     9181 tccaaagctg tcagataagg aatcggtgaa ggcttgttct ccgacacttc gtctccgaat
     9241 gtaaacgtgt ccaagtaatc agctaattta aagtgatcca agatatctgt tgctcttttc
     9301 gtaacagtgg tcgtagcaat gcctagtttc atatgacgtt cttttaagtc tgccaatatt
     9361 tcttttgcat atggttttaa gtggatggct ccgcttgtca gctgttgata aaaatattct
     9421 tcacgcttcg ctcggacttc ctgtactttt tcagggctac ctgctgcttt cactaaaata
     9481 tcaaaacttt gtttccagtt ttttccgccc caagcgtcaa cgatttcttt tgggatatgg
     9541 atatcaaatt gctgaaatcc ccaaagccag ccatcacgat acgttttttc tgtgtcaact
     9601 aacaaaccat ctaaatcaaa tattgcacct ttcatctata cattaatcct ttccaaaaca
     9661 atacacatag tttagcacga ctggtccaaa aagaacagaa gcaaagaacc agccttctcg
     9721 tttataagag ttcttggaat cgacggatat agattttctt cacagctgtc acaagcgcca
     9781 gataagcgat gactgtagca aataaccata accagtaatt gccaggaagt ggcatcaagc
     9841 ctaattcagc accaaaactt gtaaaaggaa ggacagaacc gacaataatt cctaatgtag
     9901 tgataacaaa catggcaaat gttgcgttgc tttggataaa tggtactttc ggtgtacgca
     9961 gtgcatggag cactaaggtt tgtgtccata gtgattcgac aaaccatcct gcatggaata
    10021 atgcgatgaa aatcactcgc tgtgaactat ccaatgtatg gaaacttccg cccactacag
    10081 caggacaaat aacaaaatac atcaacaagt aagtagtaat atcaaatatc gaacttgttg
    10141 gaccaaagta aaccatgaat tccccaatac tagatgcatt ccattttttt ggctcgtcca
    10201 aatattcttt atccatccga tcccatggca aggaaatgca ggaaacatca tagatcagat
    10261 tcaaaaacaa aagttgtaaa ggcagcattg gtaaaaatgg caggaacgta cttgcaatca
    10321 gcacggaaaa catattgcca aaattagaac ttgctgtagc cttgatatat ttcatgatat
    10381 tcccaaaagt ttctcgtcca gaaagaaggc ctctttccaa aatcgtcaaa tctttttcta
    10441 aaaggatcac gtctgcagat tctttcgcaa tatccacagc tgtatctaca gaaataccga
    10501 tatcagccac tttcattgca ggagcgtcat tgataccatc tcctaaaaat ccgacagtat
    10561 gaccattttt acgtaaagct gtcgtcaaac gtgctttttg ctgaggattc aattttacga
    10621 atacttcatg gtcttcagct acttgtgcta attcatgatc actcatttcc gagattttct
    10681 caccggtaac caattcattg atctctagac ctacttgacg gcacactgaa cgtgtaacta
    10741 attcgttgtc cccagtcaga acttttacag ctacaccatg ttctttcaga gctttcaacg
    10801 cttgtttcgt tgtttctttt ggtggatcaa ggaaagcaag ataaccaatc aaaaccatgt
    10861 ctgactcatc tttgactgaa aattctccaa cgacgcttgg attggtcttt tgtgcgacac
    10921 caatcactcg taagccatct tcattaagtg actgtacttt tgcaagtacg gcttcttttc
    10981 gttcttttgt taatggtgta acagtaccgc caagatcaat aaatttagaa atgttcagca
    11041 tttcttcaat cgcacctttt gtgatcattt gtgttttacc agctggatca gcaaccacaa
    11101 cactcatacg acgacgttca aaatcaaaag gaatttcatc cactttttga taattgatct
    11161 tatctgtatc taaagtttct gttgcttcat caatgatagc cacatctaac aaatttttca
    11221 gccctgtttg atagtagcta tttagatacg catggcgcaa aacacgatca tcttcatttc
    11281 cttcacaatc catatgatat tcaagaatga ttttatcttg tgtcaatgtc cccgttttat
    11341 ccgtacataa cacatcgatt gcaccaaagt tctggatggc attcaaattt ttgatcactg
    11401 ttcctttttt ggccatcaca cttgctcctt tgaccaaatt cgtcgtaacg atcattggaa
    11461 gcatttcagg tgttagacca actgctacag atagtccaaa aagaaaagct tctagccaat
    11521 ccccttttgt aagcccattg atgacgataa ctgctggagc catcaatgac ataaatttga
    11581 tcagtagcat ggatgtttta tggatgccta attcaaagct tgattgaatt ggtttttcag
    11641 atagcgtttc tgctacatga ccaaatagtg tttcatttcc aacagaaaca atgattcctt
    11701 ccgcacttcc actgatgaca ttacttccca taaagacaag attttcgtaa cttgtttcgc
    11761 tttgctgatc gtcttcacat actttcgcat gcttttctac tggatagctt tcccctgtca
    11821 atgctgcttg ggaaatgaat aaatcctttg cggacaataa acgcatatcc gctggtatca
    11881 tatcccctgc tgaaagccga acaagatctc cacagacgat ttcttccata ggaatctctg
    11941 tgtactttcc attacgtttt acagctgccg ttactttcac aagtgatttc agtttttcag
    12001 ccgcttgatt ggaacgtacg gactgaatca acgtcattgt cccgctgacg ataaccatag
    12061 tgaagataat ggctacaccg aaaagatctt tatctccagg agctgctaat acatattccg
    12121 tgatgaatga aataattcct aatgcgatca acactaatgt aaatggcgtg atgtatgctt
    12181 tcaatatttc tacaatgaat ggtgtttttt tgccatatga aatcgcattt tcaccgtaat
    12241 tttctcttga acgttcgatt tgttcttctg tcaatccatt tgctgatgca tggaatagtt
    12301 caaataattc ttgtttcgtt tttccagcaa aagctgcata gattttttgt gtatctttct
    12361 ttttttccat ctcaatctct cctttgtgtc caaaagacag ctgttctcgc tgcttttggt
    12421 ctttagctat tcatcggatc gatagagaaa aaactgaaag gggctgagaa cagatagata
    12481 atagccctgg cctttcctct agatccttgt ttttcgaatg actgtcatcc atttgttctc
    12541 atctccttta ctaagtaatt ttaattcatg acttccaatc atttttcgaa tagttatttt
    12601 tccaattaga ccacctcctt tttatttttc accgatgggg atttgcggca acaaaaaaac
    12661 ctctcgccaa atactcagcg aaaggtttga aaaagcatat taaaaaaagc ttctcagatc
    12721 tcatcgttga gttttgacac tgtacaacgt aaaaagcaga tacctgcttt tagctacctt
    12781 atgaaaagcc ttatctcgac aattcctgtt ctacccattg gcgtctctcg acgtttttgg
    12841 gcagtagcct atgtttgtat aggagcctca cctaacaaat cttattcggt tttccttcgt
    12901 taatataaca actaaaaaag aggatgtcaa atcaattttc catgtttttc atactttttt
    12961 taaaatacac acgttatatt cctgtctcac gcggttttat ttgtctcatt ttccacctcc
    13021 cgctataata gaaatatagt aggaaacgag gtgctgttat ggaaagaaca cttgttatta
    13081 tcaagccaga cggcgtgaga cgccatttag tcggaagcat catccaacgt tttgaagcaa
    13141 agggactggc cattgctgaa atgaagtttg aaactatgac tcctgaatta gcaaaagaac
    13201 attatcagca cttgactgag cgcagttttt ttgatgaact gatcgattac atgacttccg
    13261 gtcctgtcgt ttatcttgtg ctggtcggcg aggaagtgat cgatatcgtc cgtaagatgg
    13321 ttggagcaac aaaagctgcc gatgctgttc caggtacgat ccgaggagac tacgcgctgc
    13381 cggggactga aaacatcatt cacgcttctg attcccgtga tgctgcggta aaagagatcg
    13441 cccgcttttt cccgccattc gatataaaca aaccgtctga aaaagcggcg aagtgataca
    13501 aattctaaac tgctggtcta gttgctgggt tcagcaatgg ccagcagttt tttctctaag
    13561 gacctccgtt gattctttcc taacatatat tcgagcactg tgaagaattc ttggtagtct
    13621 ttcgtctttt cttcccctaa agcagcagaa atcaatcttt gataataatc tgccatcaat
    13681 gtttcataga tcactgtact tctttcttta tgtgctaagc tccgtttcat atcttcattc
    13741 acactacgtg cctttttcaa ccgaccattt tctatataaa acgaagtcag gttcattaaa
    13801 aaagtaaaga gatactgctc atgattgttc aactgtgcta atcgtcgcat tctttttttg
    13861 attttcaaat aattgttctc aatgaaccga tcactgaata tccaaggaaa atcagctaga
    13921 atagatagtt caaattgacc atagtctggt atctgcatca agtattcttc aatgattcgg
    13981 cattcataac gtaaaaattc aaattctgtc tcagatactt ctgttttttc gaccatgtga
    14041 agattcaaaa ccaaataata cagatcttct gttttcttaa aatgcctacg gttattgctg
    14101 atctctttat aaggatcaaa gctgtcttct tgtacccgat ctagcattcg tctttttttc
    14161 tttaacttta ttggttcatc cagctggttt cgcatccatt catattctgc aagtgtcatg
    14221 ttcattcgct ctaaaaatga tctcaatgtt acaaatgaca tttttttcac tgaatttgtc
    14281 tcaatcccga ctagagaagt cttaaaacag attccttccg ctaattggga ctgtgtcaac
    14341 ttcttgttga ctcgaagttt cttgatcaat tcaccatcat acataatagt tctccttttt
    14401 aatttaaatt tttccacatt caataaatag atacgttaaa aaggaaaaat acacgaaaaa
    14461 aataaaaaaa tgtttttttc ataaaaaata ccaaccttca agcattagaa tgttgtctaa
    14521 ctactgaagg ttggtttgat tgtttattga ttattttttt gctgttcaac gtctgttctt
    14581 gttactggat ataagttggt tgttgtttta ttaccatttt ttgaaaagac acttgtcgaa
    14641 tgttcgcctt tttgcttttc gattgcttca ttacgttccg cttcattttt atagtcatat
    14701 tttttcggat caatcgtctc aaatccgttt ggcacataaa accgcaagag attttcctga
    14761 ttcagcttat ctgaaagact taacgcagtc ttgacttttt cctgatcttt ggagatttcc
    14821 tcatcgattc ctgctgcttt cgtatcgatg atttctcctg tctgattatt gtaagctttt
    14881 cctcctagga cggtgtattt gggtgtcaca aagttcccat ttcgaaaagc aactacttga
    14941 tcatgctgag aagataataa gtctgtacca aaatgaagat aatctttatc atcgattccc
    15001 aatagatgta gtaatgtcgg caaaacatcg atttctccac cgtattcatg attgactgtc
    15061 cctttagtat aaccaggcat atggatcatc aatggcactc gttgcatctg tgcgttgtca
    15121 aattcatccc atgtatctgg atctttacca agagcgcttg ctaaatcttt attatctgta
    15181 ttcgagatcc caaaatgatc cccgtaaatc acaaagattg aattttggta aataccagat
    15241 tttttcaaat acgtaaaaaa ttgttccaat gattgatcca gataatgtgc cgttcgaaca
    15301 taattatcta ctgtgctatt gccagtattc aaagatggaa agtcgaaatt cttgtcatcc
    15361 gtataataag gcgtgtggtt ggttacggaa agaaatttcg tgtaaaacgg ctgttgtaga
    15421 tgctcaagat attgggcaga ttctctgaat aaatctttat ctaatatccc ataacctaac
    15481 gtttcgtcgg attcatcaaa ataagatcga tcaaagaaat tgtcataacc taagttttta
    15541 tatacatgat ctctattcca aaaactagct acattcccat ggaaaacagc gcttgtatag
    15601 ccttgctttt gtccaaggat cgctggtgcg gcttgaaaga cattgtctga cccaagttct
    15661 gtgaataatg agccttgagg taaaccaaat gtgccagttt ccaacatatt ttcagcatca
    15721 cttgtctttc cctgtcctac ttcatgaaag aaattgtcaa agctgatcgt tgcttgattc
    15781 tggaaaatac tatttaaaaa cggtgtgact tcttgtccgt ctaccttcat attaatcaaa
    15841 aactgctgga aactttctaa atggagaacg atcacatttt tccctttagc gatcccaaat
    15901 gtttcgggat ttggctctgc ataatgtttc tttgtataat ctaaaacttc atcaatccca
    15961 ttactgcttg catgcgcgcg aacactgcta gtcattcctg ttttgattcc gtcataaata
    16021 gtatacgcat cgattcctag atatttgaca atatatgaac ggtcaaatgt tcgctgcagc
    16081 aattgtggac ggttggcttc gctcagcgct agatttcctg aaaaaataag ccctgaaaga
    16141 caggtaacag cgatagccat cggtttgccg acagggttgc ttttgatagg tattttcttg
    16201 accttcaacc aaaccagtag cccaatgaac acagcgatat ccagccagta gatgacatca
    16261 tggggcttca tcaaagaaaa ggagcttcct gacaatcctt gcgacacttt cgaaaagcct
    16321 aatacagatt tgactgtaat gaaatctgtg aattcccgat aaaaaataat attcaagtac
    16381 aacaaaagcg tatttaaaat atcaatgatc aaaagaatag ctaacgctgg ctttggcttt
    16441 ttaatataca aagaaaggcc aaaaaacaat aaggtagtcg caattgggtt gatccacaag
    16501 ataaagtact ggatcgtacc ttccacacct aatgaaaaat ctgcatagta ggcaatgatc
    16561 gtcttcagcc agaaaaagaa aacagctgtc aaaacgattg ctaaacgatt ttggcacaat
    16621 tttttaagtt gtgtcacgta tatcacttct ctctattcac attttttctt attttgctcc
    16681 tgaaaaatga aaatttccta aaaaagttgt tatcttaaga tttttttatt ctttctaaag
    16741 attattccgt ccacttttca cagcataaaa ccgctgcgat gtaagcgatt aaactaatga
    16801 agagataaaa gtcttgtggt gaccgcttca ctccacggta ttcaaaagcc agtttctcgg
    16861 tattcgtaca aaaaaagagg ctgtgacaaa attcttgtcg cagctcctta tttcttgatg
    16921 caggacagct ttttcacaac ttcttcctta aacggtgttc tcctgccaac tcctcggcca
    16981 caagtcacaa tatttataaa acatgagaag ctgttttttg aaattgttcc ttgtggctca
    17041 gagttaaacg gcaggctcaa gacctcttga tacacggtgt tcaatcagct gaccctcggt
    17101 attagattat gtcaggacgc taattttaca acctcttggt aaacggtgtt caaaagcttg
    17161 catctgcggt aataagccca accaaacgaa aaatataagg agctattttt tgaaattgct
    17221 ccttgtggct cagagttaaa cggcaggctc aagacctctt gata
//
LOCUS       DACCVZ010000061        17152 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.061, whole genome shotgun sequence.
ACCESSION   DACCVZ010000061 DACCVZ010000000
VERSION     DACCVZ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17152
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.061"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(734..1912)
                     /locus_tag="IVW63_001995"
                     /pseudo
     CDS             complement(734..1912)
                     /locus_tag="IVW63_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
     gene            1942..2352
                     /locus_tag="IVW63_001996"
     CDS             1942..2352
                     /locus_tag="IVW63_001996"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860264.1"
                     /translation="MVTLFYRRDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNI
                     DDVKSKILTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSG
                     EKVTFKINFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            2433..3053
                     /locus_tag="IVW63_001997"
     CDS             2433..3053
                     /locus_tag="IVW63_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860265.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            3754..4038
                     /locus_tag="IVW63_001998"
     CDS             3754..4038
                     /locus_tag="IVW63_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7860266.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            4041..4958
                     /locus_tag="IVW63_001999"
     CDS             4041..4958
                     /locus_tag="IVW63_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7860267.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            4951..5733
                     /locus_tag="IVW63_002000"
     CDS             4951..5733
                     /locus_tag="IVW63_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP7860268.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            5734..6414
                     /locus_tag="IVW63_002001"
     CDS             5734..6414
                     /locus_tag="IVW63_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7860269.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            6407..7303
                     /locus_tag="IVW63_002002"
     CDS             6407..7303
                     /locus_tag="IVW63_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7860270.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            7498..9147
                     /locus_tag="IVW63_002003"
     CDS             7498..9147
                     /locus_tag="IVW63_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAP7860271.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            9741..10676
                     /locus_tag="IVW63_002004"
     CDS             9741..10676
                     /locus_tag="IVW63_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860272.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGFFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            10669..11439
                     /locus_tag="IVW63_002005"
     CDS             10669..11439
                     /locus_tag="IVW63_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7860273.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            11855..12838
                     /locus_tag="IVW63_002006"
     CDS             11855..12838
                     /locus_tag="IVW63_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HAP7860274.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            13285..14322
                     /locus_tag="IVW63_002007"
     CDS             13285..14322
                     /locus_tag="IVW63_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP7860275.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(14411..14734)
                     /locus_tag="IVW63_002008"
     CDS             complement(14411..14734)
                     /locus_tag="IVW63_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAP7860276.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(14721..15428)
                     /locus_tag="IVW63_002009"
     CDS             complement(14721..15428)
                     /locus_tag="IVW63_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAP7860277.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            15514..15855
                     /locus_tag="IVW63_002010"
     CDS             15514..15855
                     /locus_tag="IVW63_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HAP7860278.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(16026..16874)
                     /locus_tag="IVW63_002011"
     CDS             complement(16026..16874)
                     /locus_tag="IVW63_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860279.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
BASE COUNT         5461 a         2916 c         3574 g         5201 t
ORIGIN      
        1 taatgaaaaa cgagaaggaa gatgacttta aagtagttta gtatgaaggt cgattgataa
       61 aacgatgtgg attaatgcta aataatgagt aatttttcaa taatacaaaa actgtgtaca
      121 gtattagaag tagagaaacg ctagcgtcga aaaaaagata tttttcgtga aaagtaatag
      181 gggctaaaaa gaaagtatac aatttattta tgtttctaag catataaaaa agagcgttga
      241 aaggaatatt tccccttcaa cgcttctttt ttagaagatt ttaatgacca tctcaacttc
      301 attttcaggt ttaggtaatt catggaagct tgtgtttatc gtgcttaatt gatcaactaa
      361 ccatgtttta ctttttgact cgtagacaaa tctaaaatta atatcattgt tctcgtgttg
      421 aagaggtttc tccaaataat ctggtgaata ttcatagtca acgtaacctg ctaatacaaa
      481 agaaagcagt ccattattta gtgtcagatt taacggatgg tcgtaagctt ttattttttt
      541 aatgtcatat tgtacatctt atgaagactt aatgactact tgtagtcaat agatttaaag
      601 tatttatttt ctcatttatg tatcaagaat aaatactgat ataataaaaa ttatatcaat
      661 gttttgatga agtaatttgg agggagcgtc aataattttg tgtaaataac tcgtccttct
      721 gcaaaataat gggttactca gtaaacattg aagctaatgt atccgtcact tgttggaagc
      781 ctttatggct tctatttaag aatttttgat tgtatgtatc aaagatggat actaggaaac
      841 gctctagtga ttcttcattt tgaaactgct cttttctgcg gctgtatttc ttgatttgtt
      901 tcttgaaaga ttcgattaaa ttagttgagt aaatgcttcg gcggatacca ggcggaaact
      961 cataaaaagt caataaatct tgatttttta tcagtgactg cgtcacttta ggataagttt
     1021 tttgctactt ctcaatcata ctccctaaaa aggtatttgc ctcttccttt gagctagctt
     1081 gataaacagc cttaaaatca tcacagattt cttttcgatc tttgacacgt actttatgag
     1141 caatattacg ggaaacgtga acacagcaat gttggtattt agctttagga taaatctggt
     1201 gaatcgtatc tttcatgcct tttaagccat cggtaataaa cagtaagaca tcatgaaccc
     1261 ctctggagta aatgtcctgt aacaactcat tccaaacgta ggtcgattca gtcggagcaa
     1321 tcgcataact tagtacttct ttagtgccgt cttctcgtat accaatggca atatagattg
     1381 cttctttgga gacggtttgc cgttttaaag gaatataagt agcatccatg aaaatagcga
     1441 catacttatc atttagagtt ctaactttaa atgcatttac ttcttcagtc agcactttag
     1501 tcatgttgga catggtttgg ggcgtgtagt gatgcccata cattttctca atcaagtctg
     1561 cgatttccga catggtaata ccttttcgga agaggtgaat gacggtctcc tctaagatat
     1621 cattcgtccg tctataagca ggaacagtct gttgcttgaa ctcgccgttg cggtcgcgcg
     1681 gaatctggag atgaagttcc ccgtactcgg tcttgaccgt acggtcatag gagccgttac
     1741 gagaattccc cgtgttaaaa ccaatgcgat cgtacttttc gtaatcgagg aaagccgtta
     1801 actccgtttt gagaagcgta ttgacagctt tttccaaatg gacacggaat aattcattca
     1861 aatcgccttt gttcgctaga gtctttagaa tttctgtagt aaaatcgttc atatggaagt
     1921 cctcttttct gtgaatgtgt tgtggtaact ctattctaca gaagggactt ccttttttct
     1981 atttacacaa aatattttac actctcgtca aatataaaaa ctagtacgaa attaatttgt
     2041 aaattattta agcttgataa aataagcaat atcgatgatg taaagtccaa gatattaaca
     2101 agaaaagtaa gcgaaccagt aaagctaacg gcacaagata aaaaaaatgg aattgttctt
     2161 tatggtgatg atgcaaagta taactataat tgggatacct cctcagaagc tgaggtatta
     2221 agtattccta ctaccgatac ttcaggggaa aaagtcacct ttaaaataaa ttttataacg
     2281 gcaatttcta agttggagta tgggaagcaa aaaaagagag ataacaatga tcaatatcta
     2341 cctaaaaaat aacgaattaa tgatgcatat gttaaagttg tttttttgaa ttaaacaact
     2401 caatttattc agttatatgt tcatcgcagc aagtgaacat taatcgagtt ataaaattaa
     2461 taggagctaa aaatataaat aaagttcgat cagaatttat ttttccagaa gattttttta
     2521 actggttttt ttatcaattc agtgaatgca agcgactctt aggtgagaat tattacttaa
     2581 aaggaatcgg cggatttatg gggaatgtgg ctgatgaaca aaatattata aaaggaatat
     2641 ctgaacaaac atcagagctt acagtaacta aagcatttat aagtaatggt gaaagtttga
     2701 aaaatgtaac tgcgcgaatt agaaaagaaa atgaagtaga cattgttttt ggaattgacc
     2761 atgaatgtaa ttcagtgata tatgtaacac aatcagcaaa tttaattctt tttgagaatg
     2821 gttgcaagga cgattttatg gtggtctatt tgtacgatat actaattcca aaacttcgtt
     2881 ccttatatat gtcttctgaa agtatttttg tgagtgaaca aaagggatct ttctcgaaaa
     2941 aaataggtat tgaagtaatt gaatcgatta tgtgtcataa tcatattacg ctagaagaat
     3001 tagaaatttt gatagggcaa aaaaataata acacgaaaat acaagtttct tagaaatcat
     3061 tttttattga gatatctaga taaatgattt attcttcaat caaccaactc gccaagctga
     3121 ggtaatgttt tgaggtaatg ataacataca actttttata ccctagtaaa actctataaa
     3181 caaagactta ttaatttcgc atgaaataca ttcctgtaaa atgcaataaa atagagtttt
     3241 gtttaaccag gtcttaagaa agcccgtaaa gcttcacagt tctcaaaacg ttaattgcga
     3301 ttatcgttcg agttcacgag ttacgagaat cgtactgggc gaagcaatgc tgagcgcagt
     3361 taccttaatc ctaacttttc tggcactttc cacaatttgg aaagtgcctt ttttgtgttt
     3421 ttagctatgt taataggtag gattcttggt ctataatatc attcgatcta taaacaaacg
     3481 ggaaaaagat aaagtatcat caaacaatat tatttatccg cttctgaggt tgtgacagaa
     3541 gtggtcagct tcaagaaata agaaggaatt tacaaaaatt gcttctcatg tttgataaat
     3601 attgtgactt gtgaccgagg agttggcagg agaacaccgt ttattcggaa gaagggattg
     3661 tgaaaagtct tttgtcataa cctcttattt ggtagctaat tgtaaatccc aaacggcatg
     3721 tattattttt cataagtccg tttttaagga ttaatgtttt cttttgcttt ttatatggtc
     3781 tggcttcagc gagaagttcc aacgcatata caaggacgtc tgatgtcaac gataacaacg
     3841 attaccatgg tggccagtcc acttggatta gcactgtttg gtgcgctctt tgattggcag
     3901 acaactcaac cacgtctgcg agacagtctg atttttcttg aaattcaatt ggaaaattta
     3961 cactttcttt atacatttct ggctgctttc tttatacccg tcaactatac ttcacttatc
     4021 aataagaaag aaggataagt atggattttg gaaatgaaac ggtcttgaaa gcaactggta
     4081 taaccaaaaa atacggtgct gccaaagcat tagataaagt atcgatcgaa atcaaacgtg
     4141 gaatgatcta tggtttgatt ggggagaatg gagcgggtaa gtctaccttt atgagaacta
     4201 ttatgggttt gatctcgatt gatgaaggtt cgatcgaatt atttggaacg acggatttgc
     4261 aggcagcaag acgacgtatg ggtcaatcga ttgaaacccc tgctctttat ccagaattaa
     4321 ctgcaagaga taacctacgt atccaagcag cgaacggcgg tgtgtcggat agagaaatcg
     4381 aagacctgct gaaaatgatg cgattggaaa atacagggaa aaagaaagca aagaatttct
     4441 ctttaggtat gcgccagcgt ttagctattg caaatgcact gatcacgaat ccagaatttt
     4501 tgattttgga tgaaccgacg aatgggatgg atccagcagg gatggcagaa atgcgagaaa
     4561 tcatccaacg tttggtaaaa gaacggggca tcaccgtctt gctttctagc cacttgctag
     4621 atgaattgtc acagatcgcc actcactacg gtattttgca tgaaggacac ttgatcaaag
     4681 aattatcgaa agaagaattg gcacaagaat ctcgtcaatt tataaaaatt gacacttcgg
     4741 cgacggaaca agcagtaacg gttctcgact ctcttggtta tagggattat tttgtccaat
     4801 ctagccgtgt tatccagctt tttgaaggaa ttgaccaagt agcagccatc aatcaagcat
     4861 tggtagaggc aaaagttcct gtggatggta tccacctagt tgggcaaaaa ctggaagatt
     4921 atttcttaca attaactgga ggcaatccac atgtttaatc tattaactgc tgaaaaaata
     4981 aaagtatgga agagccgtaa aatgtgggtc tcactaggac tgatggtcgt acttccgctt
     5041 ttttattctt ggaacgaatg gtatatgcat acaaaatacg gcaatgaatt aaaccaagca
     5101 acggatacag tcatcaacgg tgcaacaggg attttaatgg tggaaaaaat ggctgcatgg
     5161 attcttctgg ctttcgcagc atttgcgtgc ttttatattg gggaagaatt tcaaaacggt
     5221 acgattcgca atacgttatc tttaggacgg aatcgaatga cttattatgt gtcgaaactt
     5281 ctcgttacgc ttttgatcac aacacttggc gtggttttga ttacggggct agccatgatt
     5341 gcttacacac ttgctttcgg atttggtgaa gttgagggaa tcaaaaacta tggaaattat
     5401 gttctaaaag tatttcctgt attgcttctg ctgatattag cgacattatc tgttccagtg
     5461 gctttgacat tcatcactag aagtaccagt gtcagtttgc ttctttcttt tctttatatc
     5521 atgggaacgg ccttcgttcc cggtgttttc gcaaaaatca aaggcttgga atttctaacg
     5581 gagtggttta cggaaacgtg gctcatgtat acggactttg cgcaacaagc aacttattcg
     5641 caagcaccga aaatgattct ggtcagtcta gtaacaatcg tggtatcatc agctctagga
     5701 atgtttattt tccaaaaatc tgacattaag taggtgttcc tgctggaaac tattttgatt
     5761 atcgaagacg atgaagctgt tcattcttta ctggaggagg ttcttgaaca gagatacaaa
     5821 cttcttgatg cttattcagg tacggaagga aaattattgt taagcacata tcctgtcgat
     5881 ttgatccttc tagatctcat gcttccaggg ctttcaggtg aagcattgtt agcagaaatc
     5941 cgacagacat cgaatgttcc gatcatcgtt ctttcagcaa aaagcgatca aagagataaa
     6001 gtttccttgt tggcagcagg agcggatgac tatgtgacga aaccatttga tatcgaagaa
     6061 ctgttgttac gaatcggcat ccaacttcgt catcagactt ctgtccaagt aaaagatctg
     6121 tcgcaacgca tctattacaa ggaaatctta ctggacaaag agtcgaggga tgtaaatgtg
     6181 aatggtgtgg ctgtccattt gacaggaaga gaattcgatc tgctgaagct ttttttagaa
     6241 catccgaaaa aagtattttc gcgagcaaat ctttatgaaa cagtttggca agaaccatat
     6301 tttgatagtg agaaaacagt gaatatgcat atttccaatc ttcgagggaa actagcaaag
     6361 gcacatgctg tgtatattca tacggtgtgg ggagtggggt ttagatttga ttaagtggct
     6421 gttgcttctc gttgttatct ttatgggaag ttttattttc ttcctgcaaa gggaaatcaa
     6481 gagattaact aagaaaatcg ccactctttc tgaacgacaa gaatatggtg gtcgtctttc
     6541 agtcgaattt cgagaaaaga atctaatgga cctagtagat gcactgaata catgggtgga
     6601 tgaaaatgaa caaaaaggac aagcatttca agaaatggaa gaaaacatca gactatcgat
     6661 cgtcggcctt tctcatgatc tcagaactcc tttgactgct attaacggtt atgtacaatt
     6721 actggaacag gtagaggata cggagaaacg ggagaagtat ttaacgatca tcaaacaatc
     6781 tgttgcaaga ttactcagta tgacggatca gttttatgat cttgctcgaa tagagacgaa
     6841 gcaaaaagaa atggatctcc atacgctttc tttttctaaa gaggtggaag aagtattttt
     6901 ctctttttat gaacaatttt ctgagaaaaa tatcgaggta gcgttcgctg aacactcgat
     6961 aaatacaact gtattagcag atccgctcat gttgctgcga gtgctgcaaa atatcataca
     7021 gaatttattg cgttatgcag atggacaagc aaaggtgaca ttttcaaaag aggattcatt
     7081 cattcgatta acagtggcca atcctatcaa accaggagcg caaacctctg ttgaaaaagt
     7141 cttccagcgt ttttataccg aaaataccag ccgcacaaat acggaatcta gcggaatcgg
     7201 gctttacctg tcaaaaaaat tggtggaagg aatgggagga gagatgaccg ctagattaga
     7261 cgggggcatc ttctccatct ccgtcaagtt gcggagggtt taattggctc taatttacct
     7321 gaagtgaatg acaaaaaatt gtatctcgtt ttaaagacat cttctttttt ggaaggtgtt
     7381 tttattttgg tgtgattgat acgaattagg taacgaagac agttattttt gtaccccctt
     7441 ttcaaatagc gcaacagtgc tatactaaaa ctaacaaatc aaggaacgga gagggatatg
     7501 ggccaaagag aatttatcgt tttaattatt attgcagttg ttattttatt agttgtttta
     7561 gacatttttt cacgtttgaa agtaaaggaa acagttcgta gtaattgggg aaaaattcct
     7621 tatcaaccga gatttgataa agaagaaagt ttgaaggatg cgtggctcac ggagaaaaaa
     7681 ttccgttcat gggatagtga aatcgacgat cttacttggt atgacttgga tatgttcgaa
     7741 gtatttgaag ggatcaacag tacctattct agtgtaggtt cagaagcgtt gtatcagcgt
     7801 ttacgtagct ttgattttgg agaagattat cagttagaaa aactaattgc tttttatcag
     7861 gaaaatcctc aactgagaga aagaatccaa tatcaattcg ctcgtttagg aaaaaaagat
     7921 cataattttg caaaacaata tctagcggat ggaaaaagta aaaagattgg acgcgtaggt
     7981 ttatttattt ttcttggctt gcttccgctg gtgggtgtag gtttgcttct tttagggcaa
     8041 gtactaggaa tctatctagc aatcggtggc ttagtattca atacggtcta ttatctagtg
     8101 aagaaacaaa cactagaaac agagctgaat agcatgagtt atttggtttc aacgatttca
     8161 gccgccaatc agttagcaaa aatgacgaca ccacttcaaa aagagctgaa acagcaaact
     8221 aaaccattaa gagacatccc taaattaggt ttttcatttc gaatgaagag cgggagtgaa
     8281 gcagaattga tttttgaata tgtcaacatc atgttcatgc tgccatttat ctcctatcat
     8341 ttcgttctca ctaaattaga aaagcattca actgaagcca tcaagctgtg ggaattgctg
     8401 ggagaattgg aagttgcagc agccgttttg aattatcgca cctatatgcc gatcacttgc
     8461 cgaccagagt ttactgaggg cggtgtgaca gcgaaagata tctatcatcc attgttaaaa
     8521 gaagcggtag ttaatccagt caactggcag aagaatacat tagtcacggg ttccaatgca
     8581 tcaggaaaat ctacgtatgt caaaagtata gccatcagct gtattctagc acagacgatc
     8641 caaacagcga ttgcagaaca gtttaccctg caacctggac atgtgttgac ttccatggca
     8701 atcgaagatg atttatttga aggcgacagt tattttgttt cagaaatcaa atcgatcaaa
     8761 cgtttgctgg accaagtggc ttccaaagaa cgctgctact gcttcgtaga tgagatttta
     8821 aaaggaacaa atacgatcga acggattgct tcttccgctt cagtcgttcg gtggcttgcg
     8881 gagtatccat ctttagcatt tgtcgccaca catgatatcg aattgacaga gattttaaag
     8941 aattattgtg agaatgtcca ctttgaagaa caagtaacag aaggaaaagg aatcagtttt
     9001 gatttcaaat taaaagaagg accttcaagg acccgaaatg cgattgcctt gctgaaagtt
     9061 ttgaattatc ctaaatccat agttgaacag gcccaaaaag aaagtttgtt gttcgatgaa
     9121 cagcgtcagt ggtatccgtt tgattaactt tatcaaacga agcatgatgc gtgggtccaa
     9181 aaagacgatt atcaaaagaa gtacattgat gccaaaaaag tggcagaatt caatgggaac
     9241 gagtctgctg tccagatgat cttggaagat ttagcaaaag acgatacaaa ataaaccacg
     9301 ctgtcttcct tctagcagct tttatcgaaa aaacttagca tcagcgacga gacgcacgtt
     9361 ccatggcaaa gttctccgta aaacaaacag cgaaaacaga aattgaaaat aactatttcc
     9421 attttattta tttcggttaa aataaaagaa aaaagctttc gataaaagga cggaggaaag
     9481 cttaacatga ataaaaaaga caagaacctc agttataagg atcttctata tgtcatcgta
     9541 gtagttgctg tcggtacttt tatgatttta aaagttccag agttgtttag atagttattc
     9601 tatcgaagat gatcatgaac tagaaaacac atctcctctt tgttagcagg tgtgtttttg
     9661 tgtggaagcc aagttgtttt ttcatctgct gtattccatg atacaattaa gaatcatgtc
     9721 tataaggaga taggaaataa atggcaaatg cgcttgaaat aaataatttg aaaaagatct
     9781 atggaagtgg ggtcgaagca ttgcggggaa tcgatctttc ggtgaaagaa ggagatttct
     9841 atgcgctatt agggccaaat ggagctggga agtctacaac gatcgggatt attacttctt
     9901 tagtcaataa aacatctgga aaagtgaatg tcttcggtta tgatctggac aaggatctag
     9961 ttcgagcaaa gcaacagatt ggattggttc cacaagagtt caattttaac ccttttgaaa
    10021 cggtccagca aatcgtcgtg aatcaagcag gctactacgg tgtctctcgc aaagaagcga
    10081 tgaaacgcag cgaaaaatat ttgaagcagt ccaatctttg ggaaaagaga aatgtccgtg
    10141 cacgtatgct ttccggggga atgaagcgaa gactgatgat tgctagggca ttgatgcatg
    10201 aaccacgttt gctgatcttg gatgaaccaa cagcaggagt tgacatcgag ttgagacgcg
    10261 agatgtggga gtttctacga gaattgaacg aaaatggtac aacgatcatt ttgacgacgc
    10321 attatctaga agaagctgaa atgctttgtc gcaacatcgg aatcatccaa tcgggtgaac
    10381 tgatcgagaa tacaagtatg aaagagcttc tgtcaaaact gcaatttgaa acatttatct
    10441 ttgatttagc gccatatgat accaaacctg tgattgaagg atatgcttgt acatttgaag
    10501 atgagcagac aatcgctgtc gaagttgaac gaaatcaagg ggtgaacgga ttcttcgatc
    10561 agcttacaag acaaggaatc aaagttcttt ctatgaggaa taagtcgaat cgtttagaag
    10621 aactgttctt gaaaatcaca gaagaaaata atcatacgga ggagaaaaat gtttaatctt
    10681 tattttactg cattaaaaag tttagctatc aaggaaacga accgctattt gcgtatatgg
    10741 gtccaaacac tggttccgcc agtgatcacg acatccttgt attttgttat tttcggaaaa
    10801 atgatcggtg ggcggatcgg tgacatgggt ggtttttcat atatggaatt catcgttcct
    10861 ggtttgatta tgatgtctgc tatcactagt tcgtatgcca atgtttcttc gtccttcttc
    10921 tctcaaaaat ttcagaaaaa tatcgaagaa atcttggtag cacctgttcc tacgcatgtg
    10981 attatttggg gctttgtgat tggtggtgtg ggtcgcagta ttctcgtcgg ctctctcgta
    11041 acgatcattt ccttgttctt tgtaccactt catgtgtatt catggttcat ggtcatcatt
    11101 acattattga tgacggcaat cttgttttca ttagcaggac tgctcaacgg gatttttgct
    11161 cagtcttatg atgatgtatc gatcgtgcct acatttgtct tgcagccgtt aacttatcta
    11221 ggtggcgttt tctatgccat ctctatgtta ccgccctttt ggcaagctgt ttcaaaagtc
    11281 aatccgatcg tttatatgat ctccggtttc cgttacggat tccttggaac gatcgatgtg
    11341 ccagtagcaa catcgatgat cgtacttgtg ttattcatcg ttgttttgta cgccgttact
    11401 tggtatttga tcaataaagg aagaggattg agaagttaga aaagaggttg tgaaatcagc
    11461 gttttgacct gagtattaga gaaacaaacg ggaaaatagt tcctcatatt ttgttgtttt
    11521 ttgagcgaat accgagggtc agctgattga acaccgttta gtggagaggt tgtgaaaaag
    11581 ctgttctgca tcaagtaata agaacagcca aacaaaaata gctcctccta tttttcgttt
    11641 ggttggactt attaccgcag atgcaagctt ttgaacacca tttattccgg aaaatggact
    11701 gtgataagat ttttgtcaca gtcttttttt tgctcaatca gaaacatctt ttaagctgtt
    11761 cactttgctt ctttttttgt ttcctagtat aatgacaatg tttttgagaa agattgcgac
    11821 ttcactgctt gatagaatgg agagtaacaa ataaatgact actaattttt ggaaagagct
    11881 gccaaagcct ttttttgttt tagcaccaat ggaagatgta acagatgttg tatttcgcca
    11941 tgtcgtaaag catgcagcag caccggatgt cttctttact gagtttacaa actcagacag
    12001 tttctgtcat ccagatggaa aagacagtgt acgaggaaga ttaacattta cagaagatga
    12061 acagccgatg gttgcccata tttggggaga caagccagaa ttttttagag aaatgagcat
    12121 tgctatggca gaaatgggct tccaaggaat cgatatcaac atgggctgcc cagtccctaa
    12181 tgtagcagaa cgtggaaaag gcagtggctt gatccttcgt ccagaagtag cggcacaatt
    12241 gattgaagca gctaaagctg gcggtttgcc tgtcagcgtc aagacgcgta tcggctatac
    12301 ggaaatgtct gagatggaag aatggatcag tcacctactt catcaagata tagccaatct
    12361 ttctgtccat ttgcgtacgc gtaaagagat gagtaaagta gatgcacatt gggaagtcat
    12421 tcctaaaatc attgctttac gtgaccaaat cgctccacaa acactaatca cgatcaatgg
    12481 agatatcccc gatcgccaga caggagaaga attggccgag aaatatggcg ttgatggcat
    12541 catgattggc cgagggattt tcaagaatcc ttatgcattt gaaaaagacc cgagggaaca
    12601 tacagaaaaa gaactgatcg gactacttcg tctgcaacta gatctgcaag atcattattc
    12661 agaaatcatc ccgcgttcca tcacaggact acatcgtttc tttaaaatct atatcaaagg
    12721 atttccagga gcaaatgact tgcgagttca gttgatgaat acgaaatcta ctgatgaagt
    12781 acgagagatc ttagagacct ttgaaaaaga acatccaacg cttttcagtg aacaatgatt
    12841 tcttgcttga acaccgtgaa ttagaggtcg tgaaaaagct gtcctgtatc aagtaataag
    12901 aacagccaaa caaaaatagc tcttcatatt ttgtcgtttt ttgagctaat accgagggtc
    12961 agttgattga acaccgttta tatcagaggt tgtgagcctg ccgtttaact ctgagtcaca
    13021 aggagcaatt tcaaaaaaca gcttctcatg tttgatgaat attttgactt gtgaccgaag
    13081 agttggtagg agaacaccgt ttataagagg ttgtgacaaa agtcttgtcg caacctcttt
    13141 tttaaccaaa aaagtgcaaa tagtttactt taagtaagag aataattatg atgaataaaa
    13201 aaggtggaac aaatagcata ctatatatat tgaaatgaac actgtatgga tgctccaact
    13261 tgatgaagct aaggaggaat tcgtatgtca gaaaaggaat taatgaaggt agtcggtttt
    13321 tatgaagggt tgccgatcga tgatccaaaa agctttattg atgaaaaaga acagatacct
    13381 gtacccagtt cacgggatct tctggtaaaa gtcaacgcag tatctgttaa tcctgtcgat
    13441 acgaaacttc gccaagataa cgggataaga aatgctttac gtatcttagg ttttgatgga
    13501 gtcgggaaag ttgttgctgt aggtgacgaa gtgcaaaaat tttctgtcgg cgatcgcgtt
    13561 ttttacgcag gtacaacaac aagagcagga agcaatcaag aataccaact agttgacgaa
    13621 cgtattgtcg ctcttgcacc aaaaaatctt tcagatgaag aagctgcagc cttgccgttg
    13681 acctcattga ccgcttatga attgttattt gaaaaatttg gtctaactcc agaagaaaat
    13741 gccaatcgcg ggaaaaaaat cttagtgatc aacggatccg ggggcgtcgg ttcgattttg
    13801 aatcaactag cgcattgggc tggcctagaa gtctacgcga ctgcaagtcc gaagaatttt
    13861 gaatggctga aaaaaacagg tgtagactat ccaatcgatt atcatcacga cttaagtaaa
    13921 agttttcgtg aattaggaat cgatcaagta gagtatgtcg ctgtattatt cgatattacc
    13981 cgctactttg atcaaatcaa gcaccttgtc cgaccatttg gacatgtggg aacgatcgta
    14041 gggatcaaag agccgttaga tataggtgtt tggaaaaacc aatctatcag cttcgactgg
    14101 gagtatatgt tcgctaaaac agactataac tatgaaatcg aaacgcaagg agaagcttta
    14161 gcgcacattg ctgctttagc aaatgaaggg attatccgca gtacattgag caaggtctat
    14221 tcagatggga tgaatgcgaa gaacttgaaa caagcaacca aagacgtaga aacaggacat
    14281 atgttaggaa aagtcgttgt tagtggtccg ttcaacggat aagcaagaat acgccgattt
    14341 ttttcttatt tgactttgat aaaaacaaga gcgcatgaca gtaatttgcc ataagctctt
    14401 gtttttttat ttataataag cgaatcaacg aaagggaaag aattcctgcc aagacgatca
    14461 ccaataagct ttttgaaaga atagcagcta aaagtgtagg aactgaagcc aaagcatttt
    14521 cgagattgat ctgcggcaga tgtccgatat tttgggtaaa tagactgctg aaccataaag
    14581 cagacataat gacgatcggg acaaaactta aatactcaag caacggttgc ggtaaatcga
    14641 attttttcag taagacaaat ggtaggaccc tagaaagcca agttgctaaa gtacaaccta
    14701 aaatagtcag caatgtaaac tcaaaagaag gcatgtttga tccacacccc caatccgcac
    14761 ccaatcagtg ttacaactac aatcactaag ttgcttggga taaaaatcag tccgacatat
    14821 accagaatca aagtgagacc aatcaggatc aactgtaatc gtttagaggt gtttctatca
    14881 gaaatgactt gaagataaag taacccgata aacatagcga cgatggcgaa atccaaacca
    14941 aactttttcg gatcagtaat aaaattccct aaaagtgcgc caacaagaga agaacccacc
    15001 cacgtcaaat aagaaatcca attagctgta ttcatccaac gaaagtttaa cttttgtcca
    15061 gtatagttca atttattcat tcccagtgcg aaactttcat ctgtcagcaa tgtgccaatc
    15121 agcagatttt gaagcagccg atttttcttg aaataaggag caatcgtcat actcatcaga
    15181 atcattcggg aattgactag aaaggtcgag aaaacgatgg aaagcaatgg gctgtgacta
    15241 gcaagcatgc tgactgtgat aaattgggca gaaccagcat agaccagcag ggacatcaac
    15301 gtgacgacta gtggatgaaa tccggcagct ttcccaacga taccaaatgc aagtccaata
    15361 ccgatataac cgaaaacggt aggtaacgtg tctttgatcg cagtttttat atctaacttt
    15421 tcatccaata acaaaactcc tttagcacga cataaatttt cataattgtc gttaaacttg
    15481 tgaatattct aaatttttaa tgagcatttg tcaatggtgg gattgaaacg taaagaacta
    15541 gcgggtcgca gatttacacg tattgtttcg gtgggaggag gcgcgaaaaa tcttgcatgg
    15601 ctacaaatcc aagctgatat tttcgatgca acggtctatt gtttaagtgt ggaggaagga
    15661 cctgcattag gcgcaacaat gattgctgca ctagggttag ggtggttcga cacacctgaa
    15721 agttgttgtc agaattttat ccaatataca gatgcagtgg aacctctctt acaaaatgta
    15781 gaaaagtatc ataaaatcta tcaacaatgc cggaaaatct atccagcaac gaaggaaatt
    15841 tgtcatgact tataaaacaa aacgcgtacc taatagtcaa atgactaata ttgggtacgc
    15901 gttaagtctt ctttacttca tcctttgcat gattcgtgtt tttaaagcaa ggtctgctgt
    15961 atttcttgtg gatttaggat ggttgttatc gtttacttgc tatttttcat tgaaatcgtc
    16021 tttctttacc gtttctttag ttttttatct atttttttct tttggttaga aaattctttt
    16081 tcccgaaagt cttctttcag gatttttata gagtagcgtt ttgaataaga ggcgtcagta
    16141 tgatcgactt ggcagacgaa ccaagagaac atttgccttt tttctgcatg aggtgcttct
    16201 gctaataatt ctttccataa ataataacag tcctctatca gaagaagggt tcgttcatcc
    16261 tcaggctccc aatagaatgt ttcgagagta gcaatcactt cattgatcaa ttcgaatgcg
    16321 ggaagatagg cattttgctg aataagcgat tcaactgctt cttggatgaa ctttcgcatc
    16381 tccatgatga acttcgctgt tttcctgttt ttgtttttct tgataatatg atcgtattta
    16441 tggatgatag ttgttaattt atctgaataa tttattgcat gaaatggcat cttaactttg
    16501 aagcgttcga taaagtgcgg atgttctata agaatctctg ttaaaagctc ccgtacaaga
    16561 gaggaactag cggaggaaac aagggacgag agttcggaaa gtgagtagtt ggattttttt
    16621 attggacgtt cttcgtaagc gaataagaca gcagccatgt gtttgcattt ttttccttct
    16681 atggcatata gacaatcaca agtcatgttg gtcttttcat cccaagtgat cactacctta
    16741 taatcttccg tgccagaaac tgttgcggac aagtacttgc ttgtatagtt caaatgacgg
    16801 acaaaaccgt gcagatgata gctgtaaccg cgttccaaaa cgttttcagg aaaatactca
    16861 agccaattat tcatctagtt ctcctttcat gaaacactta tttatattta gtataaagaa
    16921 acgtttaaga aaaaagtagc tgattttaca tatttgataa tcacttttgc tcgaattgtc
    16981 aaaaattcat tctccttttc ttttcttaga gaatgtgaga aaaagtaaaa gaatagcgtg
    17041 ttttaaagat ggaacttttt ttgtttttta tttatctgac aaaaatgaag tgattttgtt
    17101 agaaataaat aattgttcca attgataaaa gaggtatgat gtatcgcaaa ga
//
LOCUS       DACCVZ010000062        16294 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.062, whole genome shotgun sequence.
ACCESSION   DACCVZ010000062 DACCVZ010000000
VERSION     DACCVZ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.062"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            426..695
                     /gene="rpsN"
                     /locus_tag="IVW63_002012"
     CDS             426..695
                     /gene="rpsN"
                     /locus_tag="IVW63_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAP7860280.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            710..889
                     /gene="rpmF"
                     /locus_tag="IVW63_002013"
     CDS             710..889
                     /gene="rpmF"
                     /locus_tag="IVW63_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAP7860281.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            921..1298
                     /locus_tag="IVW63_002014"
     CDS             921..1298
                     /locus_tag="IVW63_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860282.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            1319..1468
                     /gene="rpmG"
                     /locus_tag="IVW63_002015"
     CDS             1319..1468
                     /gene="rpmG"
                     /locus_tag="IVW63_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003550836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP7860283.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            1492..2475
                     /locus_tag="IVW63_002016"
     CDS             1492..2475
                     /locus_tag="IVW63_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAP7860284.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVIADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLEKFNHPLVFESDSSENH
                     YNGKHYHQHHQEHEFKSILLTSDQDIKKDFLFQLIDRLILTNQGSLYRFKGLIALQDQ
                     DFIVAIQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            2505..2627
                     /locus_tag="IVW63_002017"
     CDS             2505..2627
                     /locus_tag="IVW63_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAP7860285.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKQNKMKKLA"
     gene            2645..4168
                     /locus_tag="IVW63_002018"
     CDS             2645..4168
                     /locus_tag="IVW63_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAP7860286.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLIQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            4192..4431
                     /locus_tag="IVW63_002019"
     CDS             4192..4431
                     /locus_tag="IVW63_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860287.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYQFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(4624..5259)
                     /locus_tag="IVW63_002020"
     CDS             complement(4624..5259)
                     /locus_tag="IVW63_002020"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP7860288.1"
                     /translation="MVRHLFVDFQWSPEKISNRLKHEHMDFSISFITIYRAICNDLFD
                     TEPLSHGNKGLIRSLHHRGKTRHTKNHVESRGKICLTHSIHGHPKSADDRSDFGHWKA
                     DIVAGKTSGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEVLNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(5280..5498)
                     /locus_tag="IVW63_002021"
     CDS             complement(5280..5498)
                     /locus_tag="IVW63_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7860289.1"
                     /translation="MSQYCHLTILKRERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTNHLPKRKKIMLIEEKNADVITF"
     gene            5807..6634
                     /locus_tag="IVW63_002022"
     CDS             5807..6634
                     /locus_tag="IVW63_002022"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HAP7860290.1"
                     /translation="MPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGISKPIPII
                     QAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVVEEEQDI
                     RGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVDLSKILN
                     TNLFNIDETSYSMGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFAHLTDKN
                     FPGNITRAKGFLWFAQHSDFSTIFETSGSHKSIESLNYWVASLPKIECQMIIQKNPN"
     gene            6823..7230
                     /locus_tag="IVW63_002023"
     CDS             6823..7230
                     /locus_tag="IVW63_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAP7860291.1"
                     /translation="MKFLRKAGVKIGDVIIIGILIIPSFIPLFVFSIEKENETTEDAI
                     KYAIVQIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVR
                     TGWISKPGQTSICLPHKLVISIEKKESKDYYIY"
     gene            complement(7471..8811)
                     /locus_tag="IVW63_002024"
     CDS             complement(7471..8811)
                     /locus_tag="IVW63_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP7860292.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
     gene            complement(9087..9242)
                     /locus_tag="IVW63_002025"
     CDS             complement(9087..9242)
                     /locus_tag="IVW63_002025"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAP7860293.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLTDHHITHSMSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(9426..9629)
                     /locus_tag="IVW63_002026"
     CDS             complement(9426..9629)
                     /locus_tag="IVW63_002026"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP7860294.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKMLNR"
     gene            complement(9539..9871)
                     /locus_tag="IVW63_002027"
     CDS             complement(9539..9871)
                     /locus_tag="IVW63_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7860295.1"
                     /translation="MKKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(10385..10576)
                     /locus_tag="IVW63_002028"
     CDS             complement(10385..10576)
                     /locus_tag="IVW63_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7860296.1"
                     /translation="MNTLKEDFILAKNGNEEAVVAILKRFSALVHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(10674..11060)
                     /locus_tag="IVW63_002029"
     CDS             complement(10674..11060)
                     /locus_tag="IVW63_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP7860297.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFNKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            11754..12959
                     /locus_tag="IVW63_002030"
     CDS             11754..12959
                     /locus_tag="IVW63_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HAP7860298.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKDFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTGNLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            13104..13409
                     /locus_tag="IVW63_002031"
     CDS             13104..13409
                     /locus_tag="IVW63_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860299.1"
                     /translation="MLNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDA
                     KISSYLFFLIHDEFMDYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            14026..>16294
                     /gene="esp"
                     /locus_tag="IVW63_002032"
     CDS             14026..>16294
                     /gene="esp"
                     /locus_tag="IVW63_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HAP7860300.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVQAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEEPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSASAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDI"
BASE COUNT         5585 a         2441 c         3084 g         5184 t
ORIGIN      
        1 acgaaagaat cagtatgatt gaattagttc acttaatgtc tattcttata atataaggaa
       61 taatcaaagt tttaaaaaat tggcgataaa ccagttaaac ataaaagatt gaataaaaag
      121 ttatagtttc tttcatattg ccgttttaag tagaggaaaa gctacttaaa acggtatttg
      181 tgtttgattg gactaataaa agtgaattct tatttttcag agcttaaact gcatattctt
      241 ttaaatgatt tgattatctc tatgtaccga taaattcgtt ttcaaatagt tatctattca
      301 tatgagtttt atttcatgtt atttattgtt gacaagagca actcttgttg gtaaagtatc
      361 agtgtcaaaa cgtaacgatt acgatttgag atgtctaaat caaaataaaa ggagtataaa
      421 ggtatatggc aaaaaagtcg aaaattgcta aagcaaagaa acaaatggcg atgattgaaa
      481 agtacgcaga taaacgtcag gaattaaaag ccgcaggaga tcgcaccgct ctcgctaaat
      541 tgccaagaga ttcaaatccg aatcgtctga ggcttcgtga tcagacggat ggtcgtccaa
      601 gagggtatat gcgaaagttc ggtatgtccc gtattaagtt tagagaactt gcccatcaag
      661 ggttgattcc tggagtaaaa aaagcaagtt ggtaaaagga ggaaatatca tggcagtacc
      721 agcaagaaaa acatctaagg cgaagaaacg gttaagaaga actcatcaaa ctgtagtaaa
      781 accagaaatt tcatttgacg aagcgaatgg tgattataga cgtagccatc atgtatcttt
      841 aaaagggtac tataatggaa agaaagtaat taaaggagct tcaaaatagt ttaatatata
      901 acttttagga gggaatcaaa atggaaatta tttacccacc tttagttgaa gaaggattaa
      961 agtattatct tgaaacgacc cagcaatcgc tagataaatg cactttttat cgttcgatgg
     1021 tagagagagg aattattact gaaacgggtt taccgaccca acaggcaatt gaaaatggat
     1081 tagtcaaaga ttactatgag gaccaaggct tatcatttga tgatttttta agaatctatc
     1141 caatttttga agagtatgac gaggagttat ttcaatgtat tgatggttat tgggagatac
     1201 ctgttgatat gaaagaaaat ttagtttcac aattggaatc tggcgagtta acttttgaag
     1261 atgcacaaca aattcaagca tatcttgaag atcgataagt attgaaggag gaagatttat
     1321 gcgtcaaaat attattttgg aatgtgtcga aactggagaa cgtctgtatc tcaccagcaa
     1381 aaataaacgg aataaccctg aacggttaga attaaaaaag tattcgccaa aattgcgcag
     1441 acgggcaatt ttcaaagaag tgaaatagct aagtggtaaa aaggtgacaa aatgggcata
     1501 ccagttacaa tcgtttctgg gtttttaggg gctggaaaaa caacgctaat caatcaagcc
     1561 ttgcaagtct caccctaccc cagggaagaa attattataa ttgaaaatga gtttggtgaa
     1621 gttgggattg atcacaaatt attagttcat agcgaggaac gggtgttaca actaaataat
     1681 ggatgtatgt gttgcagtct tcgcagtgat ttattagcaa tattgatttc tttactggaa
     1741 acaatagaag aacatcaaca accaatttca caaatcatca ttgaaactac aggtatagca
     1801 gatccccaac caatcattca aacactttta acagcgcctc aactaagagg aagagtatat
     1861 atcgatagtt tattgactgt tattgatagt gacagttttg aacttattga aagagaacca
     1921 caagccctta agcaacttgt catagcagat cgcatttttg tgtctagaaa acaaaacttg
     1981 aatttatctg cactaaaaaa attacagaga gaaatcaaaa gtattaaccc tttatccgat
     2041 attcgaatgt tcacacatag tgaaacgatt caaaaaaagg atttttataa tttggaaaaa
     2101 ttcaatcatc ccttagtttt tgaaagtgat tcatcagaaa atcactataa tggcaaacac
     2161 tatcatcaac atcatcaaga acatgagttt aaatcaattc tcttaacttc agatcaagac
     2221 ataaaaaaag attttttatt ccaattaatt gaccggctga ttttaaccaa ccaagggagc
     2281 ctgtatcgtt ttaaaggatt gattgctttg caagatcaag attttatagt tgccatacaa
     2341 ggggtaaacg aacaggttaa ttttcaatac accactcgac aaaaagacca aaccactatt
     2401 attctaattg gaaaaatgtt ggatgaagaa aggatcaaac agagttttga taaattactg
     2461 gcggaaagca aataatgata agtattgatt aggggtaatt tctaatggag aaaacggata
     2521 tatctagtgc atatcgacga cttaaaagcc cgaatatcaa aactagaaaa agggcattaa
     2581 aaattatcaa agaacataaa caaaataaaa tgaagaaatt agcataatta aggaaggaaa
     2641 aagaatgaag aaaatcagtg taggacttat tgggatagca gctctaggat tattgggagc
     2701 ttgctccagc actaatgatg caaaagtatc gaatgataaa gatggaaaat tagaaattgt
     2761 aacaacattc tatccaatgt atgatttcac caaaaacatc gtcggcgatg aagcgaacgt
     2821 ggatttaatg gttccagcgg gatcagaacc tcatgactat gagccctcag ctaaggatat
     2881 ggcaaaagct catgatgctg atgtttttgt atatcataac gaaaacatgg aatcatgggt
     2941 accaaaagct aaagaaagtt ggaagaaagc tgggcctaat gtagtagaag gaacaaaaga
     3001 catgatttta ttgccaggta gtgaagaaga agatcatgat cacggagaag aagatcacca
     3061 tcatgaacta gatcctcata cgtgggtttc acccaaaatg gcaattaagg aagtttcaaa
     3121 tatcaaggat cagttagtta aattgtatcc gaaaaaagca aaagtatttg agacaaatgc
     3181 tgaaaagtat ttgactaaac tgaaacggtt ggatgctgac tataccacta gtcttaaaga
     3241 agcgaaacaa aaaagttttg tgacacaaca tgcagccttt ggatatttag ctttggatta
     3301 tggattgata caagttccta ttgctggact aagtcctgaa gaagagccat cttctggtcg
     3361 attagctgaa ttaaaagagt atgttaaaaa aaataagatc aattatattt actttgaaaa
     3421 gaatgctaat gataaaatcg caaaaacttt ggccaatgaa gctgggataa aattggaagt
     3481 attgaatcct cttgaaagtc ttacaaaaga acaaatggat aatggtgaag attatgtttc
     3541 agtaatggaa gacaatctaa aagcgttaga gaaaacaact atggttgctg gtgaagaggt
     3601 agttccagaa aaagaagcga aggatgaaaa gacagttgct aatgggtact ttaaagatgc
     3661 cgatgtgaag gatcgcgaat tgagtgatta tacaggcgaa tggcaatctg tttatccgtt
     3721 gttaaaagat ggaattttgg atgaagtttt cgattacaaa gcaaaactca ataaagacat
     3781 gacagctgcc gagtacaaag attattatac tactggctat aagacagata ttgatactat
     3841 caacattaaa gacaacacca ttgattttgt agtcaacggt gaacatcatc aatacacata
     3901 caaatatgtt ggatacaaaa ttttgaatta tgaaaaagga aaccgtggtg ttcgttttaa
     3961 ttttgaaact gatgatgcag gtgctggtcg ttttaaatat attcaattta gcgatcatgg
     4021 aattgcacca agtaaggcag agcatttcca tattttcttt ggtggagaaa gtcaagaaaa
     4081 actttataat gaaatgcata attggcctac tttctatcca gcttcattat ctgagcatga
     4141 gattgctcaa gaaatgatgg cccattaaaa tccaatcttt ggaggaaata catggtaaga
     4201 aaagtattat tgtctatgga ttccaagaat attgatgctt atcggcgtta tcaatttgca
     4261 aagcaaatga gattaaatgg gagtacatta gctgatattg ctgcaacttt acatgttagt
     4321 attgacacag ttcatagagt attaaaacgg gatcctgatt gttgttttat caaggtcaat
     4381 actggaagaa gtagacgttt agcaaaacgg cataatagct tggccaatta attgataata
     4441 ccagagtaga tcatttttcc cttatttgga tttgatctgc tttttattat ttcttgaatt
     4501 gtcaaatcaa gcgcaacact ttatcaaaga agacttcata aggtgttctc caatctaaac
     4561 actttctagg tctgttattc agtttttcaa tcatctgatt tatcgttgag ttatctaccg
     4621 tagctatctc tttcgatttt ggcaagtatt ctcgaatgag tctattcgta ttttaatttg
     4681 ttcattgttg ccaagggcat gaggatctgg aaaataaaag ggcatattat tcaatacttc
     4741 tgtaactgcg aaatgattgg agaattcttt tcctctatct ggagtgatcg ttttgaccgc
     4801 ctcatttgga atactgctta aaagttcaat cattttctcg ctcacataag cggctttctt
     4861 tctggggacc ttctttcctg ctaaaaggaa gcatgatttt ctgtctgtca aagtcactaa
     4921 acaagtacca ctagttttgc cagctacaat atcggctttc caatgaccaa aatcacttct
     4981 atcatctgcg gattttggat ggccatggat cgaatgagta aggcaaatct tcccacgaga
     5041 ctcgacatga ttttttgtat gtcttgtttt tcctcgatgg tgcaatgaac ggatcaggcc
     5101 tttattgccg tgtgagaggg gttctgtatc gaaaagatca ttgcaaattg cacggtagat
     5161 cgtgataaaa ctaattgaaa agtccatatg ttcatgcttc aaacgattcg agattttctc
     5221 tggcgaccac tgaaaatcga caaataaatg acgaacaatt gaccaaactc acggatcatt
     5281 tagaatgtga taacgtccgc atttttttct tcgataagca taattttttt ccgctttgga
     5341 aggtgattag tttttttctt gtttcttctc agttcatgta aaatagtaaa cgggctatgc
     5401 tgaatgtcgt tgccaattat actaatagaa aatccttctt cgtgaagcag aaagattctt
     5461 tctcgtttga gtatagtaag atgacaatac tggctcataa ttattttcct tctaggagtg
     5521 ttctcgacaa acttatacta gttggatatc gattatgact catttttatg tgttgcactt
     5581 aaagtgtaaa ttcaaggtat agaaagaggt tccctatgaa aaaataccta ttacaatctt
     5641 aactggctat cttggttcag gaaaaacgat acttctaaat catattctgt acggtgatca
     5701 cggaaaggaa attgctgtca ttgtaaatga cataggggaa gtaaatgttg atggggtatt
     5761 agtcgacaag aaaggtttta aaagaactgg agaaaaactt gtttcgatgc cgaatggatg
     5821 catttgttgt acattacgcg aagatttgat tgttgaacta gatcaattag tgcaattttc
     5881 tgacttgaat caaattgtta ttgaagcttc aggaatcagc aaaccaattc caattattca
     5941 agcaattata ttagctaaaa accctttaga cattgatttg acccaacgat tagagattgg
     6001 tgccattatt atagtagtgg atgtaaaacg tttttgggat aatttcgaaa cgggtgaaaa
     6061 gattcaggaa agaaaagctg aaggtaatgt agttgaagaa gaacaggata ttcgtggctt
     6121 gttaattgat caattcgagt gttgtaacat attactttta aataatagtg acttagtgtc
     6181 aaccaagacg atttacaaaa ttaacggtct aattgctaag ttacagtcca atgccaaaat
     6241 aattaggaca attaaaggtg aagtagactt atcgaaaatt ctaaatacaa atctttttaa
     6301 tatagatgag acttcctatt caatgggctg gttcaaagag ttagagcttg gctatcaaaa
     6361 tcatattcct gaaacagaag aatatggtat ctcaagtttt atctatcgaa atcggttact
     6421 ccttgacgca caaaaatttg cccatcttac ggataaaaat tttcctggca atattacaag
     6481 agcaaaaggg tttctttggt ttgcccaaca tagtgatttt tcgacgatct ttgaaacatc
     6541 gggtagccat aaaagtattg aatcattaaa ttattgggta gctagtttac ctaaaattga
     6601 gtgtcaaatg attatacaaa aaaacccgaa ttgaaggaag cctggcatcc gttgtttggt
     6661 gaacgcatta ataaactagt ttttattggt atgaagatgg atcaacaatg tattaaggaa
     6721 caacttgagg gttgtttaac tgattctctt aatgcagata atttccgaaa aatttcacca
     6781 tttccatgga aaaattctaa tatgtttagc cagatatcgt taatgaaatt tttaagaaaa
     6841 gctggtgtca agataggcga tgtcataatt attggcattt tgattattcc ctcttttatt
     6901 cccttatttg tattctctat agaaaaggag aatgaaacaa ctgaagatgc tatcaaatat
     6961 gccatcgttc aaattgatgg caaggaaatg gatcgcttcg atttggataa gatcaatcat
     7021 aaactcgtga attatcatcc tgcgaaggga caatataata ttgttgagat taaagatgga
     7081 agaattcgag ttaaagaaga taatagtcct gatcaaatcg cggttagaac tggatggatc
     7141 tcaaaacccg gtcaaacgag tatttgttta ccccataagt tagttattag tattgagaaa
     7201 aaagaaagca aagattacta catttactaa tctggaaata gatgaggagg tttttaataa
     7261 gaaaaagata ttattattaa taatagcagg ggctttatta agtgtgttaa gcgcttgtgg
     7321 acaagaaaaa gaagcggtga caacaggcac aagtatcttt aacgggacct gcaatggttt
     7381 agttaacagt cggttagatt acttattttg gctcttcgtc aatgagtgtt ggtgaagaaa
     7441 ttcaatagaa taatcgagat actcacacgg ctagacagct atcttgtcta gccgtgttgt
     7501 tgttctggct ttagtcagtt gggtagtgtt cttagttttc ttgaaatatt ttcctcgata
     7561 taaaaagatt cgttctcggt agttttgaaa gtttctaaag ccataggcaa ttcgttttag
     7621 tactttgata tggttgttca aacattctat agggccgttg gaatagggaa ctcgcaacgc
     7681 tcgtttgatt tctgttcgat atttcttgaa ggtcgtgaac actggttgat agtgctctgg
     7741 caactccttg tagtcttctt ttaggagcgc gacgaattca ggaacatctt gtcttctgat
     7801 agcggaaaga aaaacctggt agacttcgta gcctcgcttt aaggagtcat cataatataa
     7861 tagccgatcg actatctccg cttctgtcag atgatctcga aatgacggac gccagtagcg
     7921 atgctgacca ttcaattccc acgcattctt ttgaagtagt ctccagtatt tctttaagtg
     7981 cttcgaccga cgatcccctt ttttaaaggt cttcattact tgaattcggt ggttggtaaa
     8041 ggcccgaccg atgtgttggc taatatgaaa gcgatcggcg acgattcggg cattcggaaa
     8101 acactctttc accaatgtgc gatagggtgt atagaaatct gaaaccacta gacgtacttg
     8161 ttcacggact tttctagggt agcgcaagaa atagtcgcgt aaaggattga gttgccgatt
     8221 ttccacaata tcaatcagtt gatgggtctt gccgtccatc atgacaaagc tcatggctcc
     8281 cgagacgttt ttcaccgatt tgaattcatc gaaacacacc acttctggta acggctggtt
     8341 caaagaaacg gttttaggcc gaaggctgcg aagtattcga atgacagtgg tcggagaaat
     8401 gtgcttcata cgtgcaatca aagacataga aataggctca cttaatagct caagaatggc
     8461 ttgtttgact ctgcgggcaa tggagcagcg acgatcgcta actgaatctt ctgctaaaaa
     8521 agtctttcca cagtgtttac atttgaagcg ctgtttgtta atccgcacaa tggtcttgta
     8581 gttactgaca tcattcaata agatggatac ttttttccag ccccatttaa tgatcgtttg
     8641 cttattttga tagtggcaat ggaagcattc ctctggttga taggtcaatg tgccatcaaa
     8701 aacaaaacat gtttcgtcat taatgcgctc tttgcgaaag gcatcttcat gaaaggtaag
     8761 atttaggtct agaatatcta gtaactcttt ggtaaactct gaataggaca tcttgaaaca
     8821 ctcctttgaa tggttttcgt cgactttatt ctaaaggatt tcaaggtgtc tgtttgcgtt
     8881 tattagaaaa aagaaaaagt attggcaaca gaaggcgtca ccaacactag atattataga
     8941 tcccttattt tcttcgcttc aaattgtcaa ggagtcatca taaattttgt atggattctt
     9001 ttgtttgggt agtagtcttc taaataatct tggattaaca ccttcatctc tattttactt
     9061 ttatatttgt tggagtcgat taattctcat ttgattgatc gatgaaacgc ttcaattact
     9121 gcattgtcaa caggagtccc agtttggctc attgaatgtg tgatgtggtg gtcggtcaac
     9181 agctcttgat aaataaaaga ccgatgctgg ctacctctat cggaatgaat taccgtaggc
     9241 aattctcctt aataaatttg taatggacgg acgacaatct cttttttcat gtgtgaatcc
     9301 accatatagt aacgtagaat acgagttgct aagtcaatat aggtggacaa atagaggcga
     9361 ccgtcattac atggaatgta agtaatatcc gtcacccaaa cagcatcaat ttggttctgt
     9421 tcaaattatc gattcaacat tttttttacc atttctttga ttgttttttc tctaccatga
     9481 gaagatttgc gtcgatgaaa tcctcttgtg cataaattca tttcacgcat aagaacagct
     9541 acaacacgtt tattgatttc gattccttca tcgtaaagtt tttgagtgat ccctggagat
     9601 ccgtatcgat ctttgtgttc gtagaacact cgtcttcctc ttttagtcgt ttattttcct
     9661 gttcaagaat gtagaaatct gctttatcag gtaatctttt tccttgtcca gcaaaagcat
     9721 ttttcccgta tcgacgatat tctgaaaccc atcgggaaat tgttggacga gagatattgt
     9781 attcttcagc aattttcttg gtagttactt ttttctcaag gatatcctgt gaaatcttta
     9841 gtttaaattt acgatcatat gtttttttca atagagttca ttccttccgg taacgtaact
     9901 gatagtcaag aaaagtgtat catagcccaa cttagtatca gggtttgtca actaaactgt
     9961 ggaagttgat agataagagt ttttaacaac caaaattctc ttgactattt ttgaaatcag
    10021 acaaattttg attggacaca tagttgaata aatctaccgt cgttacggaa ggtaaatcgc
    10081 atgcttttca attctagagg agaagtcctc gttgaagtac catggcccag ttctggattc
    10141 gacctcctgc ccacttcgta cgtaaataaa gtaattttag gagtgagact gtgacaaaag
    10201 ttatttttaa gctaaaaacg aattaaaaaa cgttaataat taaaatcatt cgttttagat
    10261 tctatgaatc attatagaac gctgtaaaat cgatacttta taattataaa gaagatggct
    10321 tcaaatttat tgttcgaaat ttgaaactat ctttttactt atgtcacaga ctcccttagt
    10381 tgagttattc tttaatttcg aatttcgaga tagctagata tattgcaagc atacattctt
    10441 gataacaatc ttgatcatat tttccagttc tccaggattg cttatggacc aaagcgctaa
    10501 atcttttgag aatggccaca actgcttctt catttccatt ctttgctaaa atgaaatctt
    10561 cttttaaagt attcataaat ttaccttctt cccatgaact tataatctat ttattttttg
    10621 gggaaggagg aggacgagca aagaagcata caaaattagt tattatgcag atattaaacc
    10681 agcatttttt gaattttttt gtaaagtcga tgttttaaat ttgtcgcacc ctgtcttgta
    10741 atacccagaa cctttccaat ttctttatca gttttattaa agataaattt ttcgataaga
    10801 aaaatttgtt caggttcttt caacaaagga aggatttttg ctaattttat atcttcaaca
    10861 aggagagtca catttaaaac attaatcggt tgtttaaatt ttatagtatc tttagtaaac
    10921 aaatatggtg ggagttgatc aagttgttca tgtttttgaa tttcttcttg ttttttataa
    10981 taagtattag cggtgttcaa aatgaccttt tcaaagaatc gaatcaactg ggcatttacg
    11041 cgttcgtcgt tatctgacat attgcacacc tcctccatta agatttaaag ggaaaagagg
    11101 caaaaaacac gaaaagaagc taatgcaatt atgctgcgct gcgaataact tctataagct
    11161 cacatgcatt gataggactg ctgatgttta ttttcaaaaa tgttttttta gttgataatg
    11221 gatagttatc tttatactta gaaaagaaaa ttcatatatc ttcttaaata tcaaacatgt
    11281 ccttatggct aagaaaatgt cttgagcttt ttacgtataa taaatctttt ctaaaacctc
    11341 cttttggata atattcttat tcgtgtatag attgtatttt ttatttcttc ccccttcata
    11401 attaacaact agaaaagagt tcgaatagac acgtatttga acgaaaattt ttattggatt
    11461 cccaaattgg agtatttaga aacgaaaaat tcctattatc tgtatagtgc ttagataata
    11521 acggatcata ataattattg tctttgaact agatatatgt aaatagtatt catcatgatg
    11581 aaaaatgatg agttctcggt gataaaatgt actttttacg gtggaatata catgaaagcg
    11641 ataagtggat attttataat gaagtaagtt agcttatttt gacagaggaa tagtatttta
    11701 gataacgtat aaaatactat ttaatgatgt agaaaggaaa gagagaaaca aaagtgtttt
    11761 cagataaaga agtcttatta aagtctcttc atgtttgttt aaagttacct atcgtggttt
    11821 ttaattccga attcagtatt ataaaagagt atcgctcaga tagaactact tatttttttt
    11881 atgattataa aaagttacta actgataata ttaaaaaaac taaagatttc catttcttta
    11941 ctggtgattt taatgagatg tttcttctat acatgtttaa aaccagatat tacttatttg
    12001 gtccatttag agcaaataat attgataaag atttttttaa actaaaaatg aacaatttga
    12061 atgttgcaat ggctgataga gaacgactct ataattcatt gcaaaatttg actttgtatt
    12121 ctttaggaga cattcgagat attctgattt tagttcatta tttttttact ggaaaaatag
    12181 aagatctatt ccatgaaccg ttaattgaat atacaggaaa tctaagtaaa actatcgagc
    12241 aaatcaaaat agataatctg ttatcacaaa attacgatcc agaaatatat ctgtttcttt
    12301 atgaaaataa aatactggaa tatgttaaaa atggagatat tcgaaattta gaaaacatgg
    12361 tttttaatct gagtaatgga ataattccaa gtgttagtgg agatacgatt cggtctgaaa
    12421 aaaattattc tatcattgtt tttgaaaagt tagcacaaac gtctataaca ttaggaatgg
    12481 atataataga agcgtatcaa agtagagatg ctttgataca agaaaacgaa ttagctgtat
    12541 cgttacctga ggtcttaaaa gtgagggatt ctgggattgt ttattatact aaggaaatcg
    12601 gaaaaactaa gatagagcat ctttctccct taatttcttc tgtcgttcaa ttcatcggct
    12661 taaatatcta taaaagaatt actgtaaagg aaatagctaa ttatttttct gtaagtgaaa
    12721 ctaaattaag agaaagcttt aagaatgaaa tgcatattac gatttataat tatatctcta
    12781 agcgaaaaat ttctacggct aaaataatgt tgaaatcaaa ccatactatc agtgaagttt
    12841 ctttaggttt aggattttca gattcttcac acttttcgag agtattcaaa aagtacgcag
    12901 gtgtatctcc taagcaatat caattaggtt tagtggataa tttcaacaac attagctgag
    12961 aggttttatt ttattatgag actatatcat ttacgtagtt tggaggagtt gaggaaattg
    13021 gattttaaca aaaaattttt tgggaaattt ctgatttgag ttgtttcgta gaatctgagc
    13081 gtctaagtaa tggtaataat agtgtgttaa atgaatatga caaagtagta attaataaag
    13141 taaaaagttt atgtgaagaa gctagagaat ctatcagtca tattaatggt agcaatttta
    13201 agcaaacatt atttaatctg attaagctag atgctaaaat atcaagttat ttattctttt
    13261 taatacatga tgaatttatg gattatcaaa aattggatca gttaattgaa agagaaagct
    13321 gggaagatta ttacgtgggt ctaacttttt cagaaaagtt aaacaactac aagttaatag
    13381 attataagta tttgagtgaa agcaattaat tattcatgta gagtactaga cactttaaat
    13441 atggacaatt caattataaa gaaaaagaat caataattta atgaggctgt gacaaatgtc
    13501 attttttgtt tcgctaaaaa cgagtgaaaa aatgttgata actccaatca ttcgtttaag
    13561 attctaggaa tcattcagga atgctgtgaa accgatactt tataattata aagaaggtga
    13621 tttcaaattc cgaagaagga atttgaagtc acctttttac ttatgtcaca gtctcattca
    13681 gtaatgcggg ataaggctcc ttattccgct atttgaatac tctgaagttt aatctaagaa
    13741 agagtaatat tttgaaaaca tgcttcatcg catagaaatg aacttaattt cagaaagaat
    13801 acatacatat ctttttatat gttttcagct gctgaatggt taaaaagcac aaatatccga
    13861 aaaaaacatg aagaaatgta ctttttttgt tgtaatgtgc atgaaattct ttaagtaaac
    13921 tagttaacat aagtttagta agattcctat tctgtgaata atacgtatca gatttatctt
    13981 ttattcttac taagaaaata actattaagg gagttgattt gaataatggt tagcaagaat
    14041 aataagagag tatttctaga aaaaacaaag aaacgagtat tgaagtacag tatcaaaaaa
    14101 ttaagtgttg gggttgcatc tgttttggtt ggtgttggtc ttgtcttggg aacaactgaa
    14161 ctagttcaag cacaagatga aatttctcca agcaccccac ttgaaacagc gataagctcc
    14221 gtacaagtag gtgacaaagt agcttcgggg aatacttttc aggagaatcc tggttatacg
    14281 aaaaattata acttttcgga tttacaattt agtcctcaag aactaactgg agacacacta
    14341 aaaggcaata caattggatt tgaagtttac ggaaaacata atattgcagc atcaactaaa
    14401 aactgggaaa tccgtcttca attagatgaa cgattagcta aatatgtaga aaaaattcag
    14461 gtcgatccaa agaaaggaat tggatcttct agacggacct ttgtaagaat taatgattcg
    14521 ctgggtagac ctacaaatat ttggaaggtc aattatattc gtgcaagtga tggattattt
    14581 gctggggctg aaacaactga tacacaaact gctcctaatg gggtaattac gtttgaaaag
    14641 agcttagatg aaatttttaa agagataggc atagacaatc tcaagaccga tcgtttaatg
    14701 tatcgaatct acttggtaag tcatcaagac gatgataaaa ttgtaccagg tattgatagt
    14761 acgggctact ttttaacaga ttcagatgat ttctataata gcttagatgt atctgaaaat
    14821 aatcctgacc agtttaaaca tggatcagta agtgcaaaat atgaggaacc taatactcaa
    14881 acaaaagatg gttcaggatc cacaggtgct aatggagcta taatcttaga tcataagtta
    14941 acgaaaaatt ataatttctc atattcagct tccgcaaagg gcacgccttg gtatgctaat
    15001 tacaaaattg atgaacgatt agttccatat gtagcgggta tacagatgca catggttcag
    15061 gctgacaaag taacatatga tgtttctttt gaatcaggga aaaaagtggc tgatttagca
    15121 attgaacggc gcaaagatca tgaaaattat ggtgtaggtt caattactga taatgatctt
    15181 accaaactta ttgattttgc taatgcaagt ccacgtccag tcgttattcg atatgtttta
    15241 caattgacta agccattaga tgaaatctta gaagatatga aagcaacagc acaagttgaa
    15301 gaaaataaac catttggtga agatttcatc tttgattctt ggttgtcgga tacgaataaa
    15361 aaattaatcc agaacactta tggaacaggt tattattatt tgcaagatat tgatggtgat
    15421 ggaaaccctg acgataaaga agagagcgga gacacgaatc catatatcgg gaaacctgaa
    15481 ttagaagaag tatatgatgt tgacacaaca gttaagggga aagtattcat ccacgagtta
    15541 gcgggaacag gtcacaaagc ccaacttgtt gataaagaag gtactgtatt agcagaaaaa
    15601 actatcgctc caaatgaaaa agatggggct ccaatttcag atactgtaga atttgaattt
    15661 acgggtgtag attcaagtaa attaatcgcg aaagatgaat taaaaatcca aatcgtttct
    15721 ccaggttttg ataaaccaga agaaggttca accgttatta aggaatcacc aaaagcggtt
    15781 gataaacaaa ccgtggtagt tggatttaaa ccagatgcta aagaatcaat tcggaataat
    15841 aaaaacttac ctgaagatgc agagtattca tggaaaacag agcctgatac ttctaacgtt
    15901 actgatagta cgaaaggtat tgtaactgtt aagatcggaa atcgaacttt cgacgtggat
    15961 gtagagtttg ctgtaaaagc ttctcaagct atggaaaatg atgcaacata cgtacctata
    16021 acaacaactc cagaaacgac agttcaaagt ggaaaaccta catttgataa accagatgtt
    16081 cctttagcta aagatgcctt ttcaatttta gatgtctata ataaggactt cggtaatgca
    16141 agtgttgatg caaatactgg tattgttaca ttcactccag ctaaaggtgt aggagaatcg
    16201 gagccgatta ctggaacaat tcctattaaa attgtttacc aagatggttc tgtaggcacg
    16261 accgatttag cagtaactgt aagtaaagat attt
//
LOCUS       DACCVZ010000063        14993 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.065, whole genome shotgun sequence.
ACCESSION   DACCVZ010000063 DACCVZ010000000
VERSION     DACCVZ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.065"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..607
                     /locus_tag="IVW63_002033"
     CDS             <1..607
                     /locus_tag="IVW63_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860301.1"
                     /translation="ENQLFAGDVLEIVLNDQAGEAAAKGVQNKPSTNDEIGNHNPSDT
                     PVVYHDAPPFAPATKIVVEGGLSFLAPSKLDCGQIKATGLTQEAFGQMDIQEKLWIYD
                     QRETKSPWILTIKLSQPFTTDAGFSMQDVLYFKKAEEYQLVNEEELEIVRGQNSTNVQ
                     TDYSEYLNNGRAFKLVLTKENQIAGNYSAEMTWTLADAPTE"
     gene            627..1655
                     /locus_tag="IVW63_002034"
     CDS             627..1655
                     /locus_tag="IVW63_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAP7860302.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKTYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKG
                     AWKEKRWNLHTDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI
                     LKERRKKK"
     gene            1652..2410
                     /locus_tag="IVW63_002035"
     CDS             1652..2410
                     /locus_tag="IVW63_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP7860303.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(2496..3236)
                     /locus_tag="IVW63_002036"
     CDS             complement(2496..3236)
                     /locus_tag="IVW63_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7860304.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            3297..4550
                     /locus_tag="IVW63_002037"
     CDS             3297..4550
                     /locus_tag="IVW63_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP7860305.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            4851..5099
                     /locus_tag="IVW63_002038"
                     /pseudo
     CDS             4851..5099
                     /locus_tag="IVW63_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            5221..5547
                     /locus_tag="IVW63_002039"
     CDS             5221..5547
                     /locus_tag="IVW63_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAP7860306.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            5615..6328
                     /locus_tag="IVW63_002040"
     CDS             5615..6328
                     /locus_tag="IVW63_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAP7860307.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            6638..7490
                     /locus_tag="IVW63_002041"
                     /pseudo
     CDS             6638..7490
                     /locus_tag="IVW63_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            7611..9476
                     /locus_tag="IVW63_002042"
     CDS             7611..9476
                     /locus_tag="IVW63_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7860308.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            9524..10933
                     /locus_tag="IVW63_002043"
     CDS             9524..10933
                     /locus_tag="IVW63_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAP7860309.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            11041..11742
                     /locus_tag="IVW63_002044"
     CDS             11041..11742
                     /locus_tag="IVW63_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7860310.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            11901..12380
                     /locus_tag="IVW63_002045"
                     /pseudo
     CDS             11901..12380
                     /locus_tag="IVW63_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            13228..13803
                     /locus_tag="IVW63_002046"
     CDS             13228..13803
                     /locus_tag="IVW63_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAP7860311.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            13803..14243
                     /locus_tag="IVW63_002047"
     CDS             13803..14243
                     /locus_tag="IVW63_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAP7860312.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            14259..14960
                     /locus_tag="IVW63_002048"
     CDS             14259..14960
                     /locus_tag="IVW63_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP7860313.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         5066 a         2484 c         3161 g         4282 t
ORIGIN      
        1 agaaaatcaa ctttttgcag gagatgtatt agaaattgta ttaaacgacc aagcaggaga
       61 agctgctgct aagggtgtgc agaacaagcc aagtaccaac gatgaaattg ggaatcacaa
      121 tccaagtgat acgccagttg tttatcatga tgccccgcct tttgcacctg ctacgaagat
      181 tgtagtagaa ggtggtctct catttcttgc cccttccaaa ctcgattgtg gtcagatcaa
      241 agcaactggg ttgacgcaag aagcatttgg ccaaatggat atacaggaaa aattatggat
      301 ttatgatcag cgagaaacaa aaagtccatg gatcttaacg ataaaattat ctcagccttt
      361 cacaaccgat gcaggatttt ctatgcagga tgtcctatat ttcaagaaag ctgaggagta
      421 tcaattagtg aatgaagaag aactggaaat tgtcagagga caaaattcaa cgaatgtgca
      481 aacagattat tcagaatatt taaataatgg tcgggcgttt aaacttgtct taaccaaaga
      541 aaatcagata gctggtaatt actcagcaga gatgacatgg acattagcag atgcgccgac
      601 agaataaaga tcaaggagaa tgattgatga atcgaatatg gaataaaagt catcgaaaca
      661 actgctcttt acttctgatc cttctccttg gattcatcct ttggcagaca cctgtccatg
      721 cctccgaatt caattttgcg gtagattttg aattaccggc taatcagatt gataagaaca
      781 aaacatatat aaatgtaagg atggagcctg ggaaaacaca ggaaatcccc tacacggtct
      841 ttaaccgaac agataaatca gtaacagttg agacattgat ccactccgct acgacgaatt
      901 caaacggtgt gatcgaatat ggagaatcaa aaagtaaatt tgatgaaaca ttaagttatg
      961 atatgaaaaa cttagcaaaa acagtgggag aaataactgt ccctcctcaa agtgcggtca
     1021 ctgagacact ttcactgaaa gctccagaaa aagagctggc tggtgtggtc gcaggaggaa
     1081 tcacgtttca agaaaaaaaa gagaacgttt ctaacaaaag tacagttggt gtcgtcaatc
     1141 agttttctca agtgaaagca atcttgattc gaaatagcga aaaagagtct tccccaaatt
     1201 tgaaattaaa aaaaacttat gcggatcaaa gcgatggaag aaatgtgatt aaggcgaatc
     1261 ttcaaaatcc aaatgcttct tatatgttcg gcttgactac atcggttgaa atctacaaaa
     1321 aagaaacaaa agagccttat ctttcaataa aaaaagaaaa aatagatgta gcacccaata
     1381 caaattttga tttacttgtc ccattagaag gaaaaaaatt agctccggga cattatcaag
     1441 cggttgtgaa gggtgcttgg aaagaaaaac gctggaatct ccataccgat tttgaaataa
     1501 ctgatgatgc agcggaccaa ttgaatgaaa aggatattga tttaaaaaat cagccagaaa
     1561 catttgactg gcgatggctg atacttgttg gagtcattct tattggctta tttgctggat
     1621 tatttatttt aaaagaaaga aggaaaaaga aatgaaaaaa acaattgcat taagtaccgt
     1681 tctagctgga agtctattat tatgtacaca aagtgttttt gctgagaata agagctcagc
     1741 cactacagaa ggaacgattt ctgtaacaaa accagatgcc gcaaatcctg aagacgttgt
     1801 tccagttcct cctgttgatc caaatgatcc cgatacgccg tttacaccta acgaaccaaa
     1861 tcagggaaca tccggattac tgacgattga ccaagctcca gatcttgatt ttggaacaat
     1921 caagttaggt acagcaaaaa cagtatatgc tgcattacaa aacggaacgg acagtacagg
     1981 gacagcaaca caagtacaga atttcgtaca agtaacggat aaaagcggaa tttatgccgg
     2041 ttggaaacta tcagtcaaac gaacagaatt tattggtaca acatctgata cgaataaact
     2101 aactggttca aaggtgaaat tcaaaaacgc cgtgattcga aatagcgcaa ctaatagcag
     2161 tggaacgcca tctactattt ctggtactgg cgctgaagga attgagatcc cagcagatca
     2221 ggcagtagat ctagtaactg caggagcaaa tgaagggatt ggcacatgga tttattcatt
     2281 aggagagaat gtggaacaag ggagacaatc agtggaatta tttgttcctg tatccaatta
     2341 tgccgtagac aactacgttt caacattcac atggtcgtta acagatgctc ctacagaagg
     2401 gaaagcgtaa aatcaaatca atgacttcag ggagtggagc cgattcaagg ccaactccct
     2461 gaaatctgct atgcttacgt ctcagctctt attcatcaac tcgaagcagt tttttggaag
     2521 tcatggaaac gttcctttgt cttttcaaag atctttcgac caacgagtaa ggagtcacca
     2581 ttgaaaaatt ctaacacata atgagcagaa tcaattttct gcaattgcga taagttgata
     2641 cagtaagatt ttaatagtaa aaagtaagca tacttttcca actctgtctt caattgtttt
     2701 aaagaagtat tcactaattt atcttctgta gttgttttga ccataacttg gtttttcaaa
     2761 cctttgatac tttcaatata taaaatttcc cgaggataca ggacgagact tccacctttt
     2821 tgatcaataa agattttatc gacatttacg atttgctgtt ctttccaatt gatctgttct
     2881 agcacttgac gaatttgttc agataaattc ctgtcttttc tgatatatcc aatcggaagg
     2941 attttccgat tgatgatctc tactgcaaaa ttcgtataag cggtgaaaaa aacaatatta
     3001 ctatgtgcat tttttttacg tatttgttcg gcgacatcaa tacctgtgag tgattgcttc
     3061 aagtcgatat cgataaagaa aacatcgtga ttatcaatag tacccaactg gatcaactga
     3121 ttgatttgag agatagaagt gagctgcacg atattctcga tatgatgatt gaccaattct
     3181 ttgatgatcc attcgctgtg aaactggtta tcttctatga taaaatactt tttcatatgc
     3241 aggctcctat taaaaaaata tgtgtacatt ttgaaacaaa acaatggagg aataagatgg
     3301 tcgcaacagt gacactttat ttgaccttta ctttgatttt agatttaggt atctatttat
     3361 tcttttcgaa acaactgcta gtaaaaaaca gctttggttt tatagctttg atggtggtga
     3421 cacttttatt tcctatccct aaagtgagct ttccttacct agttggctta ttattgatgt
     3481 ttctttttta ttttactacg aaaaacctgt ttatcagctg tttgatcagt aatctttttt
     3541 ttgctatcac tggactcagc ttttttctgg tttttgatct gatggattat ttaggaaaga
     3601 gacatcttgg aacagcaagt ttttttgcac tacttatcgc atttattttc tatctattag
     3661 taaaaagtat agacaaacag acgagatttc tcaacttgct ttttacttat ccaactgaac
     3721 actattttgg aggtatttgt attttattaa gctggggcgt gatttacttg gtattgggaa
     3781 gtgttcactt ccgctcatct aattatctgc ttctatctct tttgtcgata gtcatcagtt
     3841 ttttttcttt gtttttttcc attatgttga tcagtttcca agtaaaagaa agacaacatc
     3901 aggaatcgct tcaactgtat caaataaatg aagaatatta ccatcatcta gaggaattca
     3961 aacatgatta taaaagtcta ctgttttcat taaaaattac tcttcaggaa aataaaaaag
     4021 aaacgttgga atttttagaa atcttagaag atcattctgc agctattttt gaaaaaccgc
     4081 aaatacaaca gctaacaaat attgtatccc cagctgtcag gggtgtcttt ttaaaatttc
     4141 tagaaaaagc agaatcggag aaaatcccga tccaagtagt tattcctgtc gaagtgaaaa
     4201 caatcccgat tgatctggtt gtttttattc gctgtttatc tatttttatt tctaacgcat
     4261 tcgatcatcg tgtagccgat cagagtccga ttacgatcaa tctgctggaa gaaaaagagg
     4321 gattacgttt tagtatagcg aacaaggcaa atccgacgaa tttgacgcta tcggagatgg
     4381 tcaaaagagg aaaaacctct aaaaaaaatg gcgggttagg tctatacagt gcgaaaaaaa
     4441 tgttggatgt ttacgaaaat gcagaactaa aaatcgaatt ttcaaaacag aatcactatt
     4501 tttttgtaga aatgtatctg gcatctagaa agagcaaatc agcctactga cttactgtca
     4561 aaggataagc ttgaggaaag tctacacgga gatagagaca acaacacagc atattcaaaa
     4621 gaaacagaag cgtgatgacc gttgtcaccc ttctgtttct tttgctatgt agttaaacaa
     4681 agtagttgac acttccgcta cttagtatta gtacgaaagt atacttcatg atactaagta
     4741 gataagaagt gaaaagcgga acccacgatc gtcaaaatgc taactgcttt gcttacacca
     4801 gataaaggga agagcaatat cgcttatttt aggcgtggag aagcaagaaa atccctacga
     4861 tcacacaaaa aatgctgacc cagcagttaa gagagttaga acaagatggc attgtccatc
     4921 gaaaagtcta taaccaagtc ccgcctaaag tagagtactc gctcaccgaa gaaggaaaat
     4981 cattaagaga gattctagta gcgatgtctg tttggggaga agaacgtatc gaaaaacaaa
     5041 aagcctcagg ggaagaagtc acattactgc atacacatgg tggctaccta aattactgat
     5101 ttctatgaca tttattttaa ataaaagaaa acaggagttt ttttaaaagc atcatctatt
     5161 ttttatgtaa aaaaatggta tgattaatca agtaagaaat gattggaaga aggcaagcaa
     5221 atgaatagca tggaaaaagt taaccagttt agagatgaac gtaattggcg acaatttcat
     5281 aacgaaaaag atttggctat ttctatttct ttggaagcat ctgaattgtt agaacttttt
     5341 caatggaaaa cgccggaaga agtaaaagaa acacaattag aacgaatcaa agaagaactg
     5401 gcggatgtat tgatctattc atacatgatg gcagacaacc ttcagctgga tctagatgag
     5461 atcattgaag aaaaattgat caaaaataat ttgaaatatc ctgtagaaaa aagcgcaggt
     5521 gtacgaaaaa aatacacaga gttttagaaa tgtgtcattc ggctgttgga aagagcaaaa
     5581 gaaaaacagt aaaatgagtc tggagggaga gaaaatgaaa aaaaaaggaa aagcaaaaag
     5641 atggctagtc aatatcctct tgttcctctt gttattagta ggactagctt tgattttcaa
     5701 tgaacagatc aaggattatc ttgtcagaga gacaggagat aaatatgcta tagcgaatgt
     5761 aacaaaagaa gatctgaaaa agaataacga taaagatgtc agttttgact ttgatgcggt
     5821 agaaccaatg acgacagaag gggtcatgag gtcgcagatg agaggaacag atctaccagt
     5881 gattgctagt atcgcagtcc cttcagtttc aatcaattta ccgattttca aaggcttgga
     5941 taatacgtca ctactttacg gagcaggaac attatctcca gatcaagaaa tgggaaaagg
     6001 aaattatgcc ttagcaagcc atcgtgcaac gaaccctgaa ttgttgttta caccgctgga
     6061 aaatttagag atgggtgcca agatctattt gacagattta gaaaatgtgt atacatacaa
     6121 aacatttttt aaagaaaaag ttgctcctac agatacccaa ttactgaatg aagtcgagga
     6181 aaaagaaatt gtcacactaa ttacttgtgg cgacatggac gccgtcacgc gactagttgt
     6241 acaaggagaa ctggaaagtg ttacaccgat aaaagatgcg acagatgata tgagatctgc
     6301 tttcaatcta gagacaaaaa cattttagga tactgggaca taagtcgtta cagattaaaa
     6361 acagccaaag gatatgaatc gataaggaaa aaccaatttg ctgaaaaaaa gaggaacgca
     6421 aagaggtgca tctctgattt ggttgttttc tagatagact tgtgttccag tttttttatt
     6481 ttttatatga aaaggcttgc ataaataaaa attcgatggt atgatgattt tgaataagaa
     6541 atggattgtt actgtacggc aggcaaaacc agaattcagc taagaaacag taggcgaatt
     6601 ctaggttttt ttatttttct tgagagggcg aagcaaaatg aaaattgata aaattttgaa
     6661 taacaatgtc gtcatttcga aaaatggatt cggggaagaa gtcgtttgta tgggaaaagg
     6721 actagctttt caaaaaaaag attggggacg agatttcgcc agaagcggtc caaaaagaat
     6781 ttattttaag agattctttt gctaaaaacc aattccagca gctgatggct gatattccgg
     6841 cagaggagat cgaatgggtc aaacaagtag tcgaactggc tgaagataaa ctaaaagttg
     6901 aattttcgcc taatatttat ctgacattga ccgatcatct tcattatgcg atcacacgag
     6961 caaaagaaaa tatccaactg cctaatccat tattatttga aacaaaaaaa ttttatccga
     7021 aagaatatca agcagcgaaa gaggctcttt tgttcgtgaa acaaaagacg ggtgtggaac
     7081 tttctgagga tgaagccggt tttattgcct ttcattttgt gaatagccaa caaggaaacg
     7141 aagacatgca agtgacgatg accgctacca caatggtaag agatatactg agtatcatca
     7201 gtaaattctt cggcatcgtg ttcgatgaag aatctttgaa ttatcagcgt atcattactc
     7261 atctgcagtt ttttgcccag cgttatctca aaggggaagg atctgacgag caagatgaat
     7321 ttctctacgc attagttcaa ggaaagtatc caaaagcgtt tcattgtgtc gaacggatca
     7381 atgagtatct tcgacaaacg caaaaacagg aaatggggat cgcagagcag atttatttaa
     7441 cgattcatat tcaaagagta gtaagtgaga aaaaaagcat ccaatcataa ggattgttac
     7501 tgtatggcag gcaaaacctg gattgaaaaa ataggttcac gaatgtttgt gactgttttt
     7561 ttcaatctgg gtttttattt tttaaataaa aaagaaagaa ggaaaaaaca atggataatc
     7621 aagcagttgg tcgtcgtgta tgggaagcgg taggaggaca aaagaatgtc aaaagtttag
     7681 tacattgtgc tacgcggttg cgattcagat taaaagatga atctttagca gatacgcaaa
     7741 agttaaaaga agacccggac gtgatccaag tcgtacaaag tggcggtcag tatcaagtag
     7801 tgattggcag taatgtagca gatgtttatc aatcgatcgt ggatgaggaa ggtcttgcag
     7861 tttcggagga tggaaaagaa gagtccaaaa atattttgaa tcgtctgatc gatattatct
     7921 ctagtatatt tacacctttt ctaggggcga tggcagccgc cggggtattg aaaggattct
     7981 tatcattggc aacggtgatg ggctggctga cagctgatag cggtacttat caaatattgt
     8041 ttgctgcagc agatggtgtc tttaccttct tacctgtcat gcttgctttt acagcagcta
     8101 aaaagttcaa agccaaccag tttttagcag tagcaattgc tatggcactt gtgtatccag
     8161 ctatcacagc agttgctggt gcgggagaag ctatcagttt ctttgggatc ccagtgattc
     8221 tttcaccatc tggttatact tcttctgtca taccaatcat tctagccgta tgggttcaaa
     8281 gtaaattaga gccattcgta aaaaaagtga ttccgcaatt tctgcaaatg attttagttc
     8341 cgcttgtcgt tttagtagtg atggttccat taacatttct tgctttagga ccaatcggga
     8401 cggttgccgg taatgcttta ggcggtctct tcaactcgat ttatggattt agtccaatcg
     8461 tagcaggtct aatcatggga agtttatggc aagtattcgt gatgttcggc atgcattggg
     8521 gattcgtacc gatcatgttt ttgaatatcg aacaatatgg gtttgatgta ttgatgccaa
     8581 tgcttcttcc agccatcttg gcacaaggtg gggctgcttt agctgtagca ttgcgaacaa
     8641 aagatacgaa acttcgagca ttagggattt cttctacagt gacttcgtta tttggaatca
     8701 ctgaaccaac tgtgtatggt gtgacattac ctttgaagaa accattcatt gccgcttgta
     8761 tttctggagg tattggtgga gctattatcg gattttccgg agtaaaagct ttctccagca
     8821 gtttggtcag cttattgacg attccgactt tcattaatac ggtggatggt gtagagtcaa
     8881 atgtgacagt agcagtaata gctacaggaa ttgcttttgt tcttgcattc gtaggtacat
     8941 tgattttagg atttgacgaa caaacacaag acaatcaatt agaaaacaaa catgcgaatg
     9001 caggagaacc gattacttca gcacggcata ccttaaaaag tcctttaacg ggtaaagtac
     9061 tgccattgag tgaagtacca gaccaagttt tttcttctgg cgtgatggga aaaggtatcg
     9121 ctattgatcc agaagtagga gaactagttg cacctgcaga cggagagatc acgactattt
     9181 ttccaactgg acatgctgta gggatcacaa cgactgacgg agcggagatt ttgattcata
     9241 tcgggatgga tacagtagaa ttaaatggga atggctttga gatcttagtc aaacaagggg
     9301 atctcgtcaa agcaggagat ttattgattc gttttgacat cgaagcaatt agagcagctg
     9361 gctatagcgt aatcactcca gttgtcatta cgaatactga tgcatttgcc gatatacttg
     9421 aattagacca aaaagagatt attgcaaacg aagatgttct ggcaattgta aaataaggag
     9481 gaaatcagga tgcaatcacg tttttcagaa aaatttttat ggggtggagc aactgctgcc
     9541 aaatcaatta gaaggggctt atgatcgaga cggaaaagga ctatccgttg cagatgctat
     9601 gcctggaggt aagcagcgct ttgcgattat cggcagtgaa gaatttgact ggacgattga
     9661 tcaagaaaaa tatatttacc cgaatcatcg aggaatcgat cattacgatc gtttcaaaga
     9721 agatcttgcc ttgtttgcgg aaatgggatt caaatgttat cgtttttcga ttgcctggac
     9781 acgaattttt ccaaatggag acgaaggtac tcctaacgaa gcgggattag aattttatga
     9841 tcagctgatt gatgagtgct taaaatatga tattgaacct gtgatcacga tttctcatta
     9901 cgaaatgcct cttcatttgg caaaagaata cggtggctgg aaaaatcgaa aactgatcga
     9961 cttctatgaa cgatttgctc agacagtatt agagagatac agcagtaaag tcaaatattg
    10021 gatgactttc aatgaaatca attcggcctt tcactttcca gctttaagtc aaggattagt
    10081 aaaaagcaat ggagcaggag agtaccaaaa tattttccaa gcatggcata atcaattcgt
    10141 tgcaagtagc aaagccgtaa aaatcggcca cgaattgcgt tcggatatcc aaatcggctg
    10201 catgattatc tatgcaacaa cttacagcat cgatgccaat ccagtcaatc aggcagcaac
    10261 aatgatccaa aaccaagaat tcaatttttt ctgcacggat gtccaagtac gtggagaata
    10321 ccctgcatac acagcgcgta cccataaaaa atatggagtc gatccggaaa aattagagca
    10381 aacggaaaaa gacttccagt tgctaaaaga atatccagtg gactacatcg gatttagtta
    10441 ttatatgtct acggcaatca atgagactga tccacaagca gcaacttcag aagggaactt
    10501 gctgggagga gtaaaaaatc cgtttcttga ggcaagtgaa tggggctggc agatcgatcc
    10561 agaagggctg agaatcgcat tgaatgaatt atacaatcgt taccagaaac cattattcat
    10621 tgttgaaaac ggtcttggag ccattgatca tatggaagag gatggcacga ttattgatga
    10681 ttatcggatc gattatttac gtcgtcatat cgaagcgatg gctaatgcag tagcagacgg
    10741 tgtagatttg atgggctata cgccttgggg atgtatcgat cttgtcagtg catcaacagg
    10801 agaaatgagt aaacgttacg gctttatcta tgtggatcta gacgatgaag gaaatgggac
    10861 actgaatcga tcaaagaaaa aatcttttga ttggtataaa gaagtaattg cctcaaatgg
    10921 cgtaaacttg taattaaagc agctgaatga aaaagaacac acttctcaca tgtgatttgt
    10981 gttctttttt tattttttat gtgctattct tttagtaata gtaaagcaaa gggtgacgtt
    11041 atgaaaagga cacgtgtact atacttggaa gtcgcagata aaattaaaga agatattttc
    11101 tcaggaaaat atccagtcgg ttcgatgttg ccgacagaaa gtgaattaga agaactgttt
    11161 caagtcagca aaatcactgt ccgaaaggca atcgaactgc tggcatcaga tgaatatgtc
    11221 gcaaagaaaa gtggtcgtgg gacgacggtt ctaagcaatc gtccttacaa tcgattatcc
    11281 aaagcggcaa gctttacgca aatcttggag aactcccgat atgaagtccg gaaagaaacg
    11341 ctggatttgc aattggtcca tataaagaag gaagatcctt tgttttcctt tttcggtgag
    11401 caagctgttt gttttaagcg cttatattat ttgaacaatc agccttatat ttattttgtt
    11461 cattatcttc cacaagaaat gatgcaattc agcagagaag aatttggcaa agaatctttg
    11521 tatcgtttgc tgacgaaaaa aggatatact attgactcat tttctgatga tttctcggca
    11581 gtatttttaa cagaagaaga acaaggaatt ctgaaaacag acgcacagat cggcatcaaa
    11641 cggatacgga aatcgtctac gcaaattggg gaaatgattg aatattcgga ggcggtctac
    11701 catacggagc tgcatcctta ccatattgat tatgaaacat aaataaaaaa agaggttgtg
    11761 aaaaagctgc cctgcatcaa gtaataagaa cagccaaaca aaaatagctt ctcatatttt
    11821 tcgtttggtt aggcttatta ccgcagatac acggctgttt ctggattacc atttattctg
    11881 gataaggggg tgtggcacga ttttcagaag gaatctatga accaatcact gtattgattt
    11941 tagcttcgat ggtaacccca ttcggcttga cgatcgctta tttcttaggg aaaatcattc
    12001 gtaaaaatat actcaatcgt caagaaatcg atacattgaa gaccgctttt cctatgggga
    12061 tctgtcagat cacagaggga tgtttcccta tcgtattgaa cgacttggca cgcaatgtca
    12121 tagcaacggg agtcggtggg acagtaggtg gcggattaag catgttttgg ggcgcagata
    12181 gccgtattcc ggcatcggga atgtttgcag tcgctacgat gaccagacca tgggcattca
    12241 ttggtgcatt gttagctggt tcttttgtca caggaataac cattttatta ttgaaaaaac
    12301 cagtagatcc gaatgcagaa atcatccaag aagaaaaaga ggaagaagac atatcttggg
    12361 atgatttgac aattagttag gagaggcaga atggattaca agaaaaaagt acaatagatg
    12421 taccttgaga caggaatggt atgaaagaat cagagttaga aagaatcgaa tatacagatt
    12481 ttggtttagg agcgatcgaa actgtccaga gcatcggcac cctccttgaa atgacgatga
    12541 aggaaaaatg agaacctttc gttgtcgaaa gggtctggta taccttatgt cgaaggaaag
    12601 gaaacaaaaa aactttcctg tactattcca aaaaggaaag aaagttatta tacagtaaaa
    12661 aaagaaatta ttcttcatgc tagagatcag tacacgttcg agcccaatat caaacactag
    12721 ttccaggcag gcgcaacagg tgcggttatc actgaatttt cttccagcag tgacgattca
    12781 agtgatattt ttacaaatcc agctatttat cgttaacaaa aagattttta ggagaagctg
    12841 atgaacaaaa atgatcaaat tttgatcgtt tagttcgtcg gcttttttat ttagagaaac
    12901 atcatttatc agtgaaacat aacacgagaa caaaatgatt ttttcgttaa taaaagaaac
    12961 aagtatttgt tgtttaaaat aatacacgtt attggcatat aggacgaaat cccagtatct
    13021 tctataagta agtcatttca tatcgatgaa aacacgttat ttatttttgt tttatctata
    13081 aaatggctga aaaatgattt ttttctaaat actatatata gtggcgtcta tcctatatac
    13141 cactaaaaaa ctacaaaatc tagtctttta ttttaaaaaa acacgtgtag aatgaagata
    13201 gacttttgag ttagggagtg tttttttatg aaacttactg ttttttgcgg ttcccgtttt
    13261 ggtaataaag aaagttacaa atttattgcg caaacgttag gaaaatacat ggcacaagaa
    13321 gaaatcgaac tggtttacgg tggttcatac tccgggatta tgggagtgat tagtaaaaca
    13381 gtactggaaa ataacggaaa agtcacaggt atctatccga atgggctttt tgaaactgaa
    13441 ttgcctggaa aagatgttac tacatttatt cctacagaaa cgatcgatga aagaaaggta
    13501 ttattatttg aaaagggaga tgctgtcctc gttttccctg gaggtctagg tacattggag
    13561 gaattctcac aacttctttc ttggatagca atcggtctga cgcccgacaa gccaatcgga
    13621 atattgaata ttggcggtta ttacagcggc ttgcaacaat tattagaaac ttttgcaaaa
    13681 gaggatttta tggataaaaa atggttggat caagtaatct tttccaacaa tccattggaa
    13741 ctggtcaatg aattacgagc agtatctatt aaaaatcagt tattattgaa ggaggcaaaa
    13801 taatgagtca aatatattta gcaggaccat ttttttcaga ggagcaaatc gatcgagtaa
    13861 gtcgtatcga aaaagcgttg gaggaaaaca aaacagtcac aagtttctac tctccacgtc
    13921 atcaccaaga aagcaattat gaactattca gcgctggatg ggcgcaggaa gtatacgaaa
    13981 aagatatgga agaactgaca aatgcagaat ttgttgttgc tatccttgac tttgagcatc
    14041 aaacaatcga tccaggaacg gcttacgaat taggtgtggc aactatgttg aaaaaaccga
    14101 tgatcattgt acaagaagag acggtaccta cgaacttgat gattacacaa agtctccata
    14161 cgtatttaaa atcagaccaa gctgtacgtg aatatgattt tgaaacattg cctgttgaaa
    14221 cttacgtagg cgagtactta tagaagagga agggttgtat gtcagtgatt ttgatttcag
    14281 gaacgattgg tgcaggtaag agcagtttga cggatatgct tgcaaaagag attgattcta
    14341 aaccatttta tgaaaatgtc gaagataacg aagtattgcc gctcttttat tcaaatcctg
    14401 agcagtacgc ttttttattg caaatcttct ttttgaacaa gcgattttta gcaatgaaaa
    14461 atgctttagt gaacgatgac aatgtgctag accgatccat ctatgaagat agcctgttgt
    14521 tccatctaaa cgctgattta ggtcgggtaa cggatatcga agtacagcag tacgatagct
    14581 tattagatac gatgctaaac gagttagatg atgttgctcc aaaaaaacgg cctgatttga
    14641 tggtccatat caaagtttct ttggacacga tgctagaacg tatcaaaaaa cgtgggcgtg
    14701 actatgaaca gctagaaagc gatgagacgt tatataccta ttatgaaacg ttgaacaccc
    14761 gctataatca atggtatgaa gattttgatg tatgtcctaa aatacaagtg gatggggata
    14821 aattcgattt tgtagaaaat ccagaagatg caaaaaaggt gatccgtcag atccaagaaa
    14881 aattagctga attggaagga aagcctgctg gaaaatattt tacggataac cagcatgcaa
    14941 aaggtcaaga attaggctaa aaataaaaaa ccaaacgacg ggaaagaaaa att
//
LOCUS       DACCVZ010000064        14815 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.066, whole genome shotgun sequence.
ACCESSION   DACCVZ010000064 DACCVZ010000000
VERSION     DACCVZ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.066"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(296..1024)
                     /locus_tag="IVW63_002049"
     CDS             complement(296..1024)
                     /locus_tag="IVW63_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7860314.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="IVW63_002050"
     CDS             complement(1002..2576)
                     /locus_tag="IVW63_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP7860315.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="IVW63_002051"
     CDS             2805..3743
                     /locus_tag="IVW63_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7860316.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="IVW63_002052"
     CDS             3755..4666
                     /locus_tag="IVW63_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7860317.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="IVW63_002053"
     CDS             4690..6162
                     /locus_tag="IVW63_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP7860318.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6213..6824
                     /locus_tag="IVW63_002054"
     CDS             6213..6824
                     /locus_tag="IVW63_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP7860319.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6854..8767
                     /locus_tag="IVW63_002055"
     CDS             6854..8767
                     /locus_tag="IVW63_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HAP7860320.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8895..11876
                     /locus_tag="IVW63_002056"
     CDS             8895..11876
                     /locus_tag="IVW63_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HAP7860321.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11873..13534
                     /locus_tag="IVW63_002057"
     CDS             11873..13534
                     /locus_tag="IVW63_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HAP7860322.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13574..14506
                     /locus_tag="IVW63_002058"
     CDS             13574..14506
                     /locus_tag="IVW63_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HAP7860323.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         4815 a         2333 c         2978 g         4689 t
ORIGIN      
        1 atttaaataa ctacatccat ttattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt gcaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcatc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgcttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgatga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttac taaatgaaaa
     6181 gaatagacta agcagttagt ggggggattc aaatgaacga aaacaaatgg accaaaggat
     6241 ttaattgggt ttttcaattg ttgttactaa actttactta ttttatacta atttgtttag
     6301 gatttggaat tttaggtttt ttccctgcta cgatagcttt gattgctggc gttgtgaatc
     6361 gaaaaaaata tggcttgcaa gagtctgtga agttcatgag taaaatctat aagaaaaatt
     6421 ttgttagata taatctatat tgctggtcag caactttgtt gttggccggc aatattacta
     6481 cgatctggct ttgttggcag caaagcgcac cattgtttta tttattaagt acattattat
     6541 cggtaattac actgttccta gtctttgcaa tgttgaattg ggtcgtgatc aaaagtcttg
     6601 ggttgtggat gatgggagac cgactgattg actatttgct tttcacagca acgatgttgc
     6661 caacggtagt catgcaaggc ttggtgcttg gaatttattt ccgaatattg atgattttgc
     6721 ctgtgatttt tctgtttggc ggaacagctg taacggtaat attgattagt aaattaactg
     6781 aaagagcgtt agcaaagttg ccttgtcaga tacaatcgca ctaatttttt cacaaaaagg
     6841 agtatttctt tctatgaagt taactgataa acaagtagct aatatagcct ttatccagca
     6901 acttgagatt ccattgacac aaaaagatga agaacaaata gacttgattt ttactgacac
     6961 aaaggctaat gtgcgacaaa tcaagattac taaaaatgag cagcaacgaa tttgcttgtc
     7021 ttattcacat gaagacttgc tgtatcgagg attgtttatc tgccttccac gttttttagc
     7081 tcaaggagga gagatgccat acattgaaga aacctcgatc attgagacca gttattcatt
     7141 agatgcttct cgtaatggcg tgatgaataa agagactcta aaaaaattca tttcttactt
     7201 agcgttgatg gggtacaaca cattgtatat ttacacagaa gatacctatg aagtagaaga
     7261 ccttccatat tttggttacc ttcgcggagc gtatacaaaa gaagaagtga atgaaattgt
     7321 tgaatttgct tctggttttg gcatagaagt agttccatcg atccagaccc ttgctcactt
     7381 gacccaattt ttgaagtggt atgctcaaca agaactgatg gatgatcaaa atactctact
     7441 gatcggtgaa gaaaaggttt atgcggcaat cgaaaagatg attattgcct gcaaagaaat
     7501 gtatcagaca gagcgtattc atttgggaat ggatgaagcc tatcaagcag gtctgggacg
     7561 atatttaagc ctgtatgggt attgtgatcg gacaacttta atgattcaac atatggaccg
     7621 tgtgttatca attgttgata aatataagat gaaaccaatg atttggagtg atttcattta
     7681 taagctatta gatgaaaccg gtaaagatag gtattacaat cctgatttta aactcaaagc
     7741 attagcagct aaaggattac cagcaggatt aacctatgtt cattgggact atggttcaga
     7801 tgaagtttcc tcctatgaga aagtaattga taaccatttg aaattttgtg acattgatca
     7861 ttacgtttta gctagtggtg cccatatctg ggggagacta gccccgaatc atgggaaaac
     7921 agaagcaatt gtttctgcag ctgtaaaagc ttctaaaaat aaaggtgtac gttctgtgat
     7981 gttaactact tggggagatg aagggcagga aacagagcat tggcattcct taattggggc
     8041 attaaaatta gcagattatg tctattctga agaagagtgg aatgattttg aggaaatcta
     8101 cgatcgttta ttaggaacag gtagttatca attaatgtcc gaattacgat atttcgatga
     8161 agtggatacc attacaaata acaacttaca aatggcttcc gtgagtaaac tgctactttg
     8221 gcaagatccg ttagttggta tatatgactt tcatgtagcc gctcataaca aaattgccac
     8281 tagaacaatt ggtacttatt atcatgagtt agctcagaaa ttagatatga ataaaaattg
     8341 gaatccaaaa caaccaattt taacaactat tcgtcaacga tatatacttt tagctgaaat
     8401 tttagcacaa aaggcagaac taggcatcta tttacaacac tgctgtctgg tagaagacct
     8461 tgcaggatta atggaattag cgaatcggtg tgaagcacta gccaatcgag taaatgaatt
     8521 ggcatctatt catgaaataa tttggtatca aacatacaaa acctatggtt gggaagtatt
     8581 agaacaacga tatgctgcat tagctcatcg tctgaaaacc gttgcgcgtc gtattaaaaa
     8641 tcatcttcag gggcaagatg ccctagagga gcttttggaa gaacgattac cgttttgtca
     8701 atatcaagtg ccgcttgaaa tttctggctt taattatcgg caaagctcgg tgtcaggcta
     8761 caattaacga aggaatcttc ccgttgaacg gaccacttgc tcatctaatg ggaaagtggt
     8821 tcgttttcta ttcataagta gcttaccact aactctttta ttaagaagag aaaaaaagta
     8881 ggaagtgaga aaatatgtta tcggactatt atcaaaatct gtcagttata agtgtcaata
     8941 cagaaccatt acgtaattat tatattcctt atgcaagtaa agaagaagca aaacaagagt
     9001 tagaaaggga aaaaacgagc cagtttatcg atctcaatgg tacatgggat tttcagtatt
     9061 atccttctgt ccaacagtta ccggaaaatt tttttcaaga ggcctttact gaaagctatg
     9121 atagaatttc tgttcctgga gtttggcaaa cagagggatt tgacttacct cagtatatca
     9181 atgtatctta tccaattcct tttgatccgc cttatgtacc taatgatacc ccttgtggtg
     9241 tatatcggcg tcagtttcaa attgagcaaa cagatgcacg cttttactta aatctagaag
     9301 gagcagatag taattgtttt gtttggataa atagaaactt tgtaggctat gaccaagtga
     9361 gtcatagtac atctgaattt gatgtgacca agtatttaca ggttggggtt aatgaaattc
     9421 aaattctagt gatgaagtgg tgtgatggta cctactttga agatcaggat aagtggcgaa
     9481 tgagcggtct atttcgtcca gtgtatcttc ttcaacgacc aactatgcat ctgacaagtt
     9541 atcaactacg gacgttgact gatcctaaaa aaggaagcgg aacattaatg gtttcttttc
     9601 aacgatttac tcctattgaa gtatcgttac ctatttctta cgaattattc catcctgatg
     9661 gacgtctcat agcgaaaggg gagtgttact cggaacaaca aataaatttg gatgttgaag
     9721 attgcctttt ttggacagca gaaacgccta aattatatac attactttta acatgtaatg
     9781 gtgaatattt taaagaaaaa gttggctttc gagcactgac gatcaagaat cgtaagttat
     9841 tgctgaacgg aacacctatt aaattatatg gagtcaacta tcatgacgtg aatcagcaag
     9901 gcacgccagt gatgacccga gagcagttac gtgcagattt gttattaatg aaaaaattaa
     9961 atgtgaatac tgtacgaacg gcacattacc ctaaatcacc agatttttat gaattggcgg
    10021 atgagattgg tctgtatgta atcaatgaag cagatttgga gtgtcatggt gtggttaatc
    10081 tatatgatac tgaagcgaat tatcaactaa ttgctaatga tccgacattc gaaaagccga
    10141 ttatggaccg agtgatccgt tctattcttc cttatcaaaa tcgaagctct atcattatgt
    10201 ggtctatggg gaatgaatct ggttatggag taaattttga aaaagctcaa gctttagcac
    10261 ggaaattgga tgattcacgg ttgattcata atgaacgctc gattgaacca gttattgacc
    10321 aagtgaatga ttttagtaac ttggatgtta ttagtcaaat gtatccccca ctggaagatg
    10381 ttcatcgtca ttgtcaaaga agtgatactg aaaaaccttt ttttatgtgt gaatatagcc
    10441 acgctatggg caacggtcct ggagatctta aaacgtactt cgatttgatt caacagtatg
    10501 attcctttct tggcggttgt gtctgggagt ggactgatca tgcaatcaat agaggaactt
    10561 tagaaacgcc atcttattta tacggtggtg attttggtga aaaatatcac gacggcaatt
    10621 tttgcgtaga tggtttattg accccagatc ggcaattaac agtaggtgca ttggagtacc
    10681 gtaatattca ttcgcctatt caactgattg ctgtagatga ggagctgcaa gaagtaacct
    10741 tgagcaatat aactgctttt acagccggtt cagcatttaa cctttctctt gaatggtata
    10801 tagatggaaa aaaaacagtt tatgaagtaa tgaatccttt catacttgag cctggcaaaa
    10861 gttgttcatt gcccatcaca gtacctacaa cgattcatgg tgctcatacg gttgctgttt
    10921 cgctatctgt ttataaaaat gatgagcttt atggacagca acagctcttt cttaaaaaag
    10981 aaaaaatgag attgccaaga actgctcatc ataatgatgc accacaaatt tcagtaaaag
    11041 gcacagagct gataatcaaa ggagaatcct ttatttatat atatcaatta gcaaaagctg
    11101 cgttcacttc tgtaaagatc aatcaaaagg aacttttgga acgtcctact caattttcaa
    11161 tttggcgtgc accaacggat aatgatcgta acttagtaaa caaatggaaa gcagctggat
    11221 atgctgaaat gtctttagaa atcagaaaaa aagactggaa attcgtagat gatcatctcc
    11281 tgatcgaaac gtcttatcga ggagttattc caggattaca gccaattttt acaatgcaca
    11341 tacagttgaa aataaatggt gcaggcgtaa tcaaccaaaa agtatcagtg gagaaaaatc
    11401 cgatttttcc agatttccct cgctttggga tggactggcc gttgaatgat actttttcga
    11461 aggtttctta ttgtggctat gggccgtatg aaagttatcc tgataagcac tatgctgcga
    11521 tgtttggtat ttatgagatg gagattgagg aatttgatca gccatatatc aaaccacaag
    11581 aatatggtaa ccgctggcaa tgtgattggg tatcaatcaa aaatcatcaa ggatctacca
    11641 tgacggttta tggaaactct aatttttctg ctctgcctta tagtcaagct caattaaccg
    11701 aaaagtcaca ccattatgaa ttaataaaag aaaatagaac ttggttcaat ttaagttata
    11761 aacaaaatgg tatcggctca cacagttgcg gtccttattt agaagatcgt ttccgtttta
    11821 tggaagatac ttttgactgg aatatagtga ttactttcaa aggagaaaat agatgaaaga
    11881 aacaaagatc aatcaagtca aaaaaaaatt atctcgttat caagaagttg tttatcgaaa
    11941 ccattgctta aaatggtcaa aaaataagct gaatgttcgt tttaatggat tattttatcg
    12001 tttcgaacag ttagaagaag tctggaaacc ggtaacgaat ttccaatcat gtcctgtaca
    12061 gctcataaat gatccaaaag aaacatacga tttatgtata acacaccttt ataaccagca
    12121 tttgaaaaat gacggatttt atttaaaggt tactaatgac aatcaactta cgattgaatc
    12181 agcaaacctt cgagggtttc aatatgctat ggaagcctta ttagagagtt ttttttcggt
    12241 aggagatcaa ttattattac cggaattgat tctgaaacat gaaccatcag tgaaaattcg
    12301 aggaatcatt gaagggtttt atggtatccc ctggacacat gaaatgcgcc tctctctttt
    12361 ttcatatatg aaagataacc aattgaatac ttttatgtat gcccctaaag atgatgaatt
    12421 attacgtaaa aaatggcgtg aactctacga tgcgcaagaa ttagacaaat ttaaggagct
    12481 tttatctgct gctgaggcta gcaatatcga tttttggtac ttaattagtc ctggaaatga
    12541 tattgatatt acgtgtgaag aagacattca agttcttctg aaaaagttag aacaactgat
    12601 tgagcttggc gtatttcaat ttggtctatt aatggatgat attgactatc aattaaaagg
    12661 tgctgctaaa cgccgttttc gagagccagc attcgctcat gcctatttag tgaatcgagt
    12721 agaggaatat cttagcactc ggttgtccaa tcatgaatta gtcatttgtc ctacagaata
    12781 tgataatcgt catggttctc gctatttagc aacgttaagt caagaaatac cagaacaatt
    12841 accgttcttt tggactggcc caagcacgtt agcggcgtca atttctacag aagagctgca
    12901 ggaaatggct tctgtctatc aacggccgat gctgatttgg gataatattc cggtaaatga
    12961 ttatttagag gataaagaac tattgttcat gagtccatat gagaatcgaa caccgaatct
    13021 ttctaaggag agataccagg ttacaggagt agtttcgaat ccaatggctc aattagaagc
    13081 ttcaaagttt acgatcaata gtatggctaa ttacttatgg aactgtgagc gttttgatcc
    13141 tttggaaact tggacgtcag tcgttgaaaa agtagttgga agtaaactac aaccagctta
    13201 tcttacctta accaatgctt ttccaaatca ttacacaagc agtctgcttt cagatgaaga
    13261 attactgcta gccaaagacc cagaatgggt cacaaaagaa atggctgctt tagtccaagc
    13321 agtaaaatgg atccagcaag aacaacatac atctagattg agaacagaat tggagccttg
    13381 gttacaagca atcacagaaa gttggacttt ctggcaagaa tggcaattaa aaaaagatcc
    13441 aaaagaagca gaagaatggt tggctaagaa aaaaacacac cgcataggac gtgatttagt
    13501 aactgcccat ttagagcaaa ttatcaaaag ttagatatct taaaaaataa aaagcaagaa
    13561 aaaggagaac aaaatggtca agagattaat tagtgcaaac tacagtgatg tcaagaaaat
    13621 gacgtcaaaa gagttgaagc aatccatcaa agcgagtgaa ggacgggtga ttgtttgtga
    13681 aacggttgct aatactcttc cacaatctgg agaaattacg aatgcagaag ttgcgtcagc
    13741 atttggtgca gatttgattc ttttaaatgg tttcgattgt tatcgtcctg cagtttttgg
    13801 actaccaaat gtgacgattg agaaggtttt tgatctacag caaacgattg aaaacccgat
    13861 tcctaaatta aaagaactag tcggtcgtcc tgtgggaatt aatttagaac ccattgcccc
    13921 taaaacaaat atgatgagtg agaaagtaga aatcagccaa ggaagagcaa gctctgttga
    13981 aacgatacaa aaagcagaag aactaggagt cgattttatt tgctttaccg gtaatccagg
    14041 cactggagta accaatttag aaattactaa atccgtaaaa atggcaaaaa agtatttttc
    14101 gggattgatt attgctggga aaatgcatag cgccggctca gaagagccag ttgtgaataa
    14161 agaggcgatt atttcttatg cggaagcagg cgcagatatt ttactagttc cttcagtagg
    14221 gtctatccca ggctttttag agcaagacct aattgaagcg gttcggttgg caaaaaaata
    14281 tgatttgtta acgatgtctg caatcggtac tagtcaggaa agtgcccgac cagaaacatt
    14341 gcggcaatta gccattatga ataaaagttg tggtgttgat ttacaacata ttggagatgc
    14401 tggatacggg ggattggcac cagcagaaaa tattttcgaa acctcggttg caattagagg
    14461 aatgcgacat accatcaact gcgttagccg ctcgatcaat cgctaacaaa attaaataaa
    14521 aaatggttaa attgattatt taagtgggaa catacttgag atatcagcta acttctgtca
    14581 ctttaaaaaa gggactgtga cagaagtgaa aatagacaaa aaatatccga acaagagact
    14641 aggatagcag aaaaactatc gttttgcaac gaggaccaac tggaccgtag gagcaattct
    14701 cttattgttc ggatatttcg cttgttcaag gacttatgtc tgtagtgccc ttttttggta
    14761 ggaaaaatgg tagggaacca tatcattttt aatgaaaatc aagcatttca aaagt
//
LOCUS       DACCVZ010000065        14629 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.067, whole genome shotgun sequence.
ACCESSION   DACCVZ010000065 DACCVZ010000000
VERSION     DACCVZ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14629
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.067"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            87..983
                     /locus_tag="IVW63_002059"
     CDS             87..983
                     /locus_tag="IVW63_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAP7860324.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1133..2074)
                     /locus_tag="IVW63_002060"
     CDS             complement(1133..2074)
                     /locus_tag="IVW63_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAP7860325.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2200..3321
                     /locus_tag="IVW63_002061"
     CDS             2200..3321
                     /locus_tag="IVW63_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP7860326.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3579..5081
                     /locus_tag="IVW63_002062"
     CDS             3579..5081
                     /locus_tag="IVW63_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAP7860327.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5148..5675
                     /locus_tag="IVW63_002063"
     CDS             5148..5675
                     /locus_tag="IVW63_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP7860328.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            5886..6947
                     /locus_tag="IVW63_002064"
     CDS             5886..6947
                     /locus_tag="IVW63_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP7860329.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6950..7846
                     /gene="murQ"
                     /locus_tag="IVW63_002065"
     CDS             6950..7846
                     /gene="murQ"
                     /locus_tag="IVW63_002065"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAP7860330.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7860..9842
                     /locus_tag="IVW63_002066"
     CDS             7860..9842
                     /locus_tag="IVW63_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7860331.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9907..10353)
                     /gene="nrdI"
                     /locus_tag="IVW63_002067"
     CDS             complement(9907..10353)
                     /gene="nrdI"
                     /locus_tag="IVW63_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAP7860332.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            10564..11988
                     /locus_tag="IVW63_002068"
     CDS             10564..11988
                     /locus_tag="IVW63_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7860333.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(12169..12942)
                     /locus_tag="IVW63_002069"
     CDS             complement(12169..12942)
                     /locus_tag="IVW63_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP7860334.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(12939..13844)
                     /locus_tag="IVW63_002070"
     CDS             complement(12939..13844)
                     /locus_tag="IVW63_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7860335.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(13998..14318)
                     /locus_tag="IVW63_002071"
     CDS             complement(13998..14318)
                     /locus_tag="IVW63_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAP7860336.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
BASE COUNT         4674 a         2609 c         3099 g         4247 t
ORIGIN      
        1 acaaatatag gaaacgtttt actggctttt tactatttaa acaggctatc ataggaaaaa
       61 gtgacagaga aagtgaggcg gaaaagatga acaaaaatga cgtactgcta gttgcaaaaa
      121 ataaatcact ttattttttg ccttccatcc gctctttaga tgtttggtcc ggaaaagatt
      181 tactacagtc ggaattcatt aaatcagcta gacaacagtt ggcaaattat cagctgatcg
      241 tttttttaga ttatggattt gatatggaga tggctcgacg cgtgcgccca tttaccaatg
      301 caaaaattgt gttatttttt tggaatcact tcaaagcaga acacgaggcg atgctgaagc
      361 aggcacaaga tgaaccggca atcgatgaga tttatcattt tgattttttg gaagcaaaag
      421 aacttgggct gaaacataat agttcatttt attcgaaaca tatgaatttt tcttctagcg
      481 aaccaaagac ggatctattt tttggtgcaa cgaataatgg gagaaaagaa cgagcagaaa
      541 gctataagca ggaatttata aaaagagatg ttacgaccaa ctatttcatt cttccacatc
      601 gagggaatga acaacctgga tatcttactt atgaagagta cctgaaaaaa acaggggaat
      661 cgcgcgggat tctggaactg ttgcgggagg gtcagcaagg agtgactttg cggacatttg
      721 aatccatgta ttttcaaaag aaactagtga cggataatca agcgattgct cattatcatt
      781 tttatcgtcc tgaaaatatt tttttgcttc gagaacgtga tttagatgaa ttaccggaat
      841 ttctgcatac accatttaag ccaatcctat cagagctatt ggaattttat gatgcagaaa
      901 attgggcaaa acgatttatc actaacgatt ccactattta tgagcaatac gaatatgacc
      961 tctcctctgt tgaaaacaaa taaaaaacct acattttgaa gagattatgt actgaaacaa
     1021 acaagcacaa ttcttatggc atcatgagag ttgtgttttc tttttgatct tttattgggc
     1081 ttaaaaaaag agaaccagct gctgattcag ctgattctca tcagagagcc ttttattctg
     1141 cgccaaggat tccttctttt gcatggacta attgggtcaa aaaggcacaa tatggtgtag
     1201 caatatcata tttttgtcct tttcgccaaa tggcaccatt gatgtagtcg atttcagtca
     1261 aacgatggtt tttgatcagg tcttggtaca tagatgggta atgcaacccg atgttgtcag
     1321 gatcataagt agaagcaata tgttggtaca cttcttcttg atctagtatg attccttctt
     1381 ttgctgcgat agaagcaaat tcagatacga ttgttcgaac catgctctct gccgcttttt
     1441 gcgcgcctag ttcagcaata ttacaatcca aaatcgtgca taaaccattc aatgttccat
     1501 ttacacaagc ttttcgccaa atggaataac gaacgttatg gctatagatc ggatttaaat
     1561 ttgcttcttg aaagacttct acaacttttt ttgtaaatgc ttcgccttct ggttccaagt
     1621 tctctagttc gatttctcca tcacctaaca atgtgacttt tccgggacca gctagaccag
     1681 ctgtccacat cgtgatccca aataagatat ttttctttgg cacatatttt tccagtacat
     1741 cttcatgacc taatccattt agtaaacaca aaacataagt attgtcagta ataatggatt
     1801 ggatcgaaca aaacatatca tctaattgat tggcttttgt taatgctacg atcaagtcca
     1861 cgtgttcgtt gctttcgatg atttcttctg gtgaatagat tggcagtttt gcgaccactt
     1921 ctttaccgtt aaagtcagca atcaacccat ttgtacgaat ggcttcaatg tgagcaggcc
     1981 aacgatcgat caagaggacc tcatttccgc tttgatgtag catcaatccg attcggctgc
     2041 ccattgctcc ggccccagct attgcgattt tcatgttttt tctctccttt attcaatgag
     2101 ttccctttta gtatatagaa aaatggaaga aaatagcatt gttttgtttg aaaaaaatga
     2161 aaaaaagtgt cttacttaag aagaaagtga gggatacaga tggatatttt ggcggcaatt
     2221 gattcattta aaggaagtgc ttcttcattt gaactaaatc aggcagttct aaatggctgg
     2281 gaagatcgta aaggaagaaa aatcaatgtg ccgattgcag atggcggaga aaatactgca
     2341 gaagcaatct attacgcgct caggggaaca tggcgtacca ttgatgggat ggatctctta
     2401 ttccgtcagc gaaaaatcag ctatttattg acaacttggc aaggaaaaaa caccgcagtc
     2461 atcgaatctg cacaagcatt ggggttagat ctacttgata aaccaacgga tcaaactatc
     2521 cgacttgctt ccagttatgc cttaggagaa cttattaaag atgcactgct tcaagaagta
     2581 gaacaaatta ttgtcacttt aggaggaagc gggtgtagcg atggtggtct aggattactc
     2641 caatccttgg gtgcttcttt agaagggtac acagaaggaa atcctttatt atctactaaa
     2701 aaacttcatt ttgatcgaag aaacgttctt gtttctaaag taaaattgat tatcgctgca
     2761 gatgttacca atccatatac aggtcaacaa ggagctgctt ggcaatttgg aagacaaaaa
     2821 ggaggaatag atacgacgct agctttctta gataaacaag caggaaagat tgctcagcaa
     2881 ataaaagatt tctgggaggt ggatttagat gatattccag gaagtggagc agcaggcggt
     2941 attggtggag cccttttttt gttgggagcg aagatggttt ctggtttcga tttagtcagc
     3001 caaatcactg gattggaaaa aaagatcgaa caagcagatg tcatcattac aggagaaggg
     3061 cggatcgatc agcaaacgat ccacggaaaa gttccatacg gtgtagcagt gcttgcaaaa
     3121 aaatatcgaa aaccaataat cgctatttgc ggaagtagag accaagagct agaaggactt
     3181 tctgattttc tcccaattgt cttaagtatt catttgggtc caataggttt agaagaagca
     3241 atggaacaca ggcaaacatt agaaaaaaca aaaatcttag gacagacact tagcagattt
     3301 ttcaccatcc tcccgaagta gttgacaaaa tcattttctt tatgctatcg taatttcaaa
     3361 tataggacaa agtgagggat ccgtgcattg aaaaattaag tcgattgatg aaagctgcat
     3421 tcagactgta ccttgtggag acaaggaagc agtgtgcaga ttttcgggat tggcttggtt
     3481 ttttcgatgt atgggtcttt ttgtgtgtat ccaacccttg catcctcttt agccagttct
     3541 gaaaatagga ctggtctttt tttacgaggt gatggaaaat gtctaaaatc gaaataaaaa
     3601 atctgacatt cggctacgac agccaaggca cattattatt tgaacaagca aatctaaatt
     3661 ttgacacaca atggaaacta ggacttatcg gacgaaacgg tcgaggaaag acaactttac
     3721 tgaatattct acaaaacaaa ctaccttatc aagggcaagt aatccatcag caagaatttg
     3781 cctatttccc gcaacagaca aaagataaag aacgtttaac ctattacgtg ttaaatgata
     3841 ttacggattt tgagatatgg gaaatcgaaa gagagctcca attgatgcaa acagatcctg
     3901 aaatcttatg gagagaattc agcacactat cggggggaga gaagacaaaa gtcctactgg
     3961 cacttttatt tgtggatgac actcatttcc cgttaatcga tgaaccaacg aatcatttgg
     4021 atatctctgg tagaaaacaa gtagcggctt atttgaaaaa gaaaaaacaa ggcttcatcg
     4081 tggtcagcca tgaccgggga tttatcgatg aagtagtgga ccatgtttta gcaatcgaaa
     4141 aaagtcaact ggaactttat caagggaatt tctctatcta tgaagaacag aaaaaacttc
     4201 gtgatgaatt tgaaatggct caaaatgaaa aattgaaaaa agaagtcagt aggctaaaga
     4261 aaacagcagc tgaaaaagcc gaatggtctc gttcccgaga aggagataaa acaaagaaac
     4321 aagtcggatt catcgatact gaatctagac gagtgaataa aggagcagtg ggtgctgatg
     4381 ctgcacggac gatgaaacga tccaaagcaa tcgtgaatcg gatggagacc cagatcagcg
     4441 agaaagaaaa actattaaaa gatatcgaat atatcgattc tttgacgatg aatagccaag
     4501 cgtctcacca taagcgactt ttaagcgtag aagatcttca attagggtat gaaaatctgt
     4561 tattcgagcc aattcatttt acaatcgagc ctcatcagcg ggtggcgatt tcaggtccta
     4621 acggtgcagg aaagtcatcc attatccatt atcttctggg ggcattcaac ggcaaggtta
     4681 taggagaaaa ataccagcca aaacatctga gcattagtta tgcaagccaa aattatgaag
     4741 acaatcgagg aacgttggcg gaatttgcag agaaaaacca agtagactac caagcatttt
     4801 tgaacaacct ccgaaagctt gggatggaaa gagatgtttt tcataacaag atcgagcaga
     4861 tgagtatggg ccaacggaaa aaagtggaat tggctaaatc tttatcacag ccagctgaac
     4921 tatatacatg ggatgaacca ttgaattatt tggatgtctt caatcaagaa caattagaac
     4981 aactgatctt gaacgtgaaa cctgccatgt tactagtgga acatgatcaa accttcctgg
     5041 ataaagtatc tactgagatt atttctcttg agagaatcta acccttgtaa tctcaagaac
     5101 aacaaggtat ggttaagggg aactttgcca acgaaggaga gaatcacatg ctttatgtaa
     5161 cgagacacgg agaaacaact tggaacgcac aaggattagt ttgcggacgg gcagatgtgc
     5221 cgctgactga aaaaggacag atgcaggcac agaaactagc agaaaaggta gtagatttgc
     5281 ctgttccaat cacgaaaatc atccattccc ctcttcaacg agcaagagat acagcacaag
     5341 cagttgctga tcgtctcagc ttgccgctga ccgttgatga acgattggta gaaatggatt
     5401 ttggggatta tgatggactg ccaagcaaag atgagaactt tcaaaaagca cgtttagcgt
     5461 tcgctgtacg attcccaaat ggggagtcag tcttagatgt gtatgcacgg atcgttcctt
     5521 tattgaaaga atgcatcgaa gacgaagaaa atgtctatct gttagtttgc cataatgcct
     5581 tgataagagt gatcaatgct tattttcatc cgatgcctaa tgaggggttc tttacattca
     5641 tggtagataa tacagaattg gtttcttatg agtaattatg tttttgtgtt atttaaataa
     5701 aatatttcaa ggcactgctt ttgcttagca gtgccttttt taggttatga caattctttt
     5761 gataatataa actcaacctt tagaaatgaa atttaattat tttaataaaa gtattgaaat
     5821 tttgtttctt tagatatata ctctagtcat agaaatgaag acggatacag aaaaagaggg
     5881 ataatatgtt tggcttttca atatttatga acgattcttt gtcagaagag aagaaacagt
     5941 atatccgcca aatggcatcc aatggctttg tcggtatttt cacttccatg catataccag
     6001 aagatgatgt ttcggcatat caaaagcgat tgatcgaact aggaagcgaa gcgaaaaaga
     6061 ataaactaga attgatggtc gatatttcag gagaggcatt ggaacgagcg ggtttttcat
     6121 tagaagatct aacgcctttg aaagcaattg gtgtaacagg tttaagaatg gattatcata
     6181 tttccaatca gcagattgcc gactggtcac atcaattgaa aatcagtttg aatgctagca
     6241 cgatcacgcc taaagatatc gatgaattga aagaagcaga agctgatttc tcacagattg
     6301 aagcttggca taattattat ccacgtcccg aaacagggct ggacaaagaa tggtatcaga
     6361 aaaaaaatca atggctcaaa attcaaggtc tccttgtcca aggttttgta ccaggagata
     6421 cagagttgag aggcccacta tatcaaggat tgccaacttt ggaagaacat cgagggatcc
     6481 atcctcttgc aggcgctcta gatctattag caagtaacac ggatattgtt tacatcggag
     6541 atgcaggtct gtcagaaaac gttcaggagc aatttgcttc tttccaaaaa gaacagacag
     6601 tcttgctcca tacggaacct gtagatgaag aattttacga atatatatta gggaagcata
     6661 cgaatcggca agacgatgca agagatgtca tacgaagcgt agatgcacgt tttcgagaga
     6721 ttccgcctat cccagcaaga aatacagcta cgcgtatgaa agggtctatt actttagata
     6781 acgaaaagta tttgcgctat atgggtgaga tccaattaac caaatatgat ttgccagcgg
     6841 atgaaaaagt gaatgtagta gctaaagtta tcaaagaaga gctaccattg atcaaccaaa
     6901 tcaaagctgg tatgaactat caatttataa gaaaagaagg aagataaaaa tgagcaaaat
     6961 caatttagag aacctaacaa cggaacgcag aaaccaagaa acttttggat tagatgagat
     7021 gagtatttct caagccgttc aactaatgaa caaagaagat cagaaagtgg ccgctgcggt
     7081 tgaaaaagaa ctgacaagta tcgaaccagt gattgctaac acgattgagt cctttaaaaa
     7141 aggtggacgt ctgatttata tgggagccgg aacaagtgga agactaggtg tgttagatgc
     7201 tgctgaatgc gtaccgacat tcggtgtaga accggaaatg gtcataggtc taattgctgg
     7261 tggagaagaa gcaatgactg tagctgtcga aggggccgaa gattcttatg agctagggca
     7321 agaagatcta atcaagctga atttgacaaa aaatgatata gttattggta tcgcagctag
     7381 cggtcgtaca ccatatgtga tcggtggatt agattacgca aaatcgatcg gtgctgtcac
     7441 aggaacgatt tcttgcaata aacaagccga aatcagtaaa cacgcggatt tcccaatcga
     7501 agtcgatgca ggtccagaat ttttgacagg ctctactcga ttgaagtcag gaacagcaca
     7561 aaaacttatc ttgaatatga tttctactat cagtatgatt ggtataggta aagtattcaa
     7621 taacttgatg gtcgatgtca aaccaacaaa tgaaaaacta atcgaacgct caaaacgaat
     7681 catcatgcaa gcgacagaag ctgattacga aacagctgaa aagtactttg aagaagcaga
     7741 tcaaaatgtt aagctggcta tcgtcatgat tttgacaaat agtgataaag aggaagctca
     7801 agcaaaatta gctgaagcaa acggatttgt aaaagggacc ttatgagggg gaaaagacca
     7861 tggcaaaaaa cgaactgact ttggaagaac tggcaaaaca aatttataaa ggggcaggcg
     7921 gcatgggcaa tgtagaaagc attgtccact gcatgactcg tgtgcgtatg aagatcatca
     7981 atgatgatct tgtaaatgtc tctgaattaa aagcgattcc aggagtgctt ggtgtagtag
     8041 aagatgaaca gcttcaagtc atcatcggac ctgggaaagt gaacaaagta gcacagcaaa
     8101 tggttgattt ggcaggcgtg aaattaggag aaaaactttc ttctgtaagt acagctacag
     8161 caaattcatc agcatctgga aaagaccgtg taaacgaacg ggcacaagaa atgaaagcgg
     8221 cacaaaaatc gaaacaaaaa ccatctaaaa tcaaatcggt attaaaagac atttctaata
     8281 tctttgtgcc aatgattcct gcatttgtcg gtactgggat cgtggcaggg attgccgcag
     8341 ttttagcaaa cttagtcaca gccggaacac ttgatgcagc aacatggcaa caatatatcg
     8401 atgtgatgaa catcttgaaa aacgggatgt ttagctacct agttatctat acaggtatca
     8461 atgctgcaca agtttttggt gcaacaccaa ctcttggtgg agttatcggg gccgttgtga
     8521 tgctgacagg gatgaatccg gaagcaccac tgaaaaactt atttactggt gaagctcttg
     8581 cagctggaca aggtgggatc ctaggtgtca tcttcgctgt ttggctattg tcaatcgttg
     8641 agaaaaaact gcataaagta gtacctgatg cggtagatat catcgttaca ccaactcttt
     8701 cattgattgc catcggtctg attgaaattt tcttcatcat gcctttagca ggtttcattt
     8761 ctgatggcat ggtcggtggg atcaactggg tacttggcgt tggtggagca tttgccggct
     8821 tcgttctagg cacattattc ttgccgatgg ttatgttcgg actgcatcaa attttgactc
     8881 caatccatgt gcaaatgatt gatgaaactg gtcgtacgct attgcttcca attcttgcga
     8941 tggctggtgc aggacaagtg ggtgcagcat tggcattatg gattcgctgc aaaaaagata
     9001 aagaattaac agaaatgatc aaaggagctt taccagtcgg gatcctagga atcggcgaac
     9061 cattgattta cggagtaaca ttacctctag gacgcccatt tattactgct tgtatcggtg
     9121 gaggtatcgg cggggcagtg atcggaatga tcggaaatgt cggggctatc gctattggac
     9181 cttcaggagc cgctttgatc ccattgatct ctgacggtaa atggttaggc tacatccttg
     9241 gattattggc agcttatgct ggtggcttcg ttgctacatt cttcttcggt attcctaaag
     9301 accgtttaga aaaagaagaa ttagcgactg aaacagccac agtaaatgaa gtgcctgaaa
     9361 aagtagtacc tcaaacttca gctgaaagtg tgactatcct ctcatcagtt gctgacggaa
     9421 cagttgtttc tttagataaa gcaagtgatc cagtttttgc acaaaagatg atgggtgaag
     9481 gctactttgt agaaccagaa aacggacata tctattctcc agttactggg gtagtcagct
     9541 ctgtcttccc aacgaaacac gctattggga tcacaacgcc aaatggttta gaaatcttgc
     9601 ttcatatggg aatcaacaca gttgacttag gcggtacgcc atttgatgtg aaagtaacag
     9661 aagggcagca agtgacacct gatacgcttg tagcagaagc tgacttagaa gcgatcaaag
     9721 cagcaggcaa agaaacatcc atgatcgtct tggtaaccaa tatggatcgt gtaaaaaact
     9781 ttgtcttgga aaaaacaggt aaagcaaaag caaaagcacc tgtgatggat gtcaaagctt
     9841 aatatgatag aaacaataga aacgaaagaa gaaactgaaa tctatttttc agcttcttct
     9901 tttttattat ttattgtttt ctgctaaaat ctgataaatt cgtgtcacat cagatggtgt
     9961 tccccgtaat tcataatctg ccaagaaagg aaagccaaat gtttgtgcat attgtttggc
    10021 tgttagacaa tactgattat tgaagttttt atttccgcta ccgactacac caagacaaag
    10081 tttatgattg tcttcatgtt ccagatattc acgcatcgtt tcggtcaaga tttctgtatc
    10141 accgttatct aaaccatttc cgccgtctaa ataagtagga acgaaagtaa aaaatggttc
    10201 tgtttctttc gtaaaatcac tattttcatg gatttctttt aaagtaactt caggattgac
    10261 aggatcttct gcatgcattt tttcagcata ttctgctaga tgtttggcaa aggcacgcgt
    10321 atttcctgaa atcgatatat ataaaatgtt catggatcat cctccaattc tttcctttta
    10381 gtatagcatc ttttttaagt tttttggtgg tgtaatttgg aaagggacta ggcgctttgc
    10441 ttgtataatg agaaaaaagc cggtagaatt atatttctat taaagttttt attaattaag
    10501 taaaaataaa aaaggtttgt tatacttttt gataaaagcg gttttatttt ggaggatgct
    10561 tacatggata cagagcaaca gaaaaaagga attggtttaa ttccacttgc tgccttagta
    10621 attggttcag cgattggagg tggcgtattt ggtattatga cggacatctc cggatcggct
    10681 ggcggcccag ctattttcag ttgggtactc gtaggaacag caatgttgat gctctccttg
    10741 tcgatcaata atatcaataa aaaacgtcca gatttaaaag gcgggatctt tagttacgca
    10801 gaagaaggtt ttggccgttt cgctggtttt atcagcggtt ggggttactg gctcacatgc
    10861 tggttaggca acgtagcttt tgcaacattg ttgatgagcg cattaggata tttcttccca
    10921 gtatttgaag gtgggcaaaa tctggcatcg atcgtgatga gtacagtctt tttatgggga
    10981 tatgcatggc tagtgaatcg gggagtcgaa aatgctagtt tcgtcaatgc tatcgtcaca
    11041 ttctgtaaat tagtgccatt atttttattt attgtagtag ctatcagcac gttttcgatc
    11101 caacaattca ttgataactt ttctagcgac attatattga atgcgaatgg acagccgatc
    11161 ccgttttcca gtcaagtatt gagttgcatc atggtgatgc tttgggtatt tgttggtatt
    11221 gaaggagcct ctgtcgtagg ttcacgagca aaaaaacaat cagatgttgg gaaagcaacg
    11281 attctaggga tattcggctt gattattatt tacgtcttgg tttccatgct tccatatggg
    11341 acaatgacga tgaatcagct gcaaacgatc aaggcgcagc ctgctatggg ctatgtgttt
    11401 gaaatgatgg ttggtaaatg gggagcagtc gtgatcaacg gcggtttgat catttcttta
    11461 gttggtgttt ggctctcatg gacgatctta ccgattgaaa caatgggaaa catggctgaa
    11521 gacggacttt tgcctaaagc atggggaaaa ctcaacaaaa atggggcacc aacttatgct
    11581 atcgtattga cgacgttatg tacgaatgtc tttttacttt cattattatt cactgacagt
    11641 gcttataact ttgcttacac acttggtaca gcagctattt tcttcacgtg gcttttctta
    11701 ggattgtacc aaatgaaact ttcttatcag cggaaagaat gggtccaatt tttagtaggg
    11761 cttttagcaa gtgcctttca agtatgggct atgctagtcg tagcctttaa tgaagtaatg
    11821 cttgttcttg ttcttttctt gccaggcatt tatttttacc tcaaagcacg taaggagcaa
    11881 aacgagcctg tacaacatat ccacttagat aagattttac ttataggtgt gacgatggtc
    11941 ggagtgattg caatggtttt atttgccact gggatgcttc acgtatagaa gtataaaaga
    12001 agtataaaga gaggttgtga gcctgtcgtt tattcaaaaa catactagga aaggagctgt
    12061 gacacaaatg ttgtcacagc tcctttttca gaataaacgg tgtttaagag acagccaatc
    12121 ggcaataagg ctgaacgtct ctttcacagc ctcttttttg atgagtcatc atacattttt
    12181 tcgcttaaat acgagatatc ctaatgctaa gaacaaaacg atgtaagcta aattaccgaa
    12241 tagcatttga ttagtagaaa gatgagtcaa ttgcttcatg atctcttcgt ttccaatttg
    12301 gttttgcaga ttcaacatac tgatcggatt ccatttgatc cactcccatt tttggatgag
    12361 tgcaataagg ataccagata tgattgacga agcaaaataa aagacgattc ctgctgagat
    12421 ggatgcgccg gaactattga taaagcaagc aatcatcaac actaaactta aaatcagcca
    12481 taaaccgata taactaccca aagtataagt gaacaagctt tggatcagtg tttgaccagt
    12541 agaaaccttc tccgtgaagg aaatcgaagg gaaaagaatc agtttcatca acacagtgac
    12601 aataatagct aaaaggtata aataaacaga ataaataact aatgtgatcc atttgcttac
    12661 taatatttct cctcgagaat actttcgata aaggagattt ttcaatgtac catattgtgc
    12721 ttccatcgaa atgatcgtgc ttgcagctgc aatcatgata aagacaatcc aagatgtggc
    12781 actaaaaagc tgagcagtca tttcaactgg atcaatgatc gtcgtgtatt ttttggctag
    12841 aagtgctgtt cctatgagca aaacaactaa tagaacagat aaaacagcag ttgacttttt
    12901 cttgatcaat ttaaataatt cttgttttac aagcaatgtc atttttcttc ttcccccttt
    12961 actgaatcca gaatttccaa tagagaagat tccaaatcat tcgtcagatg ctggacgtct
    13021 gtcacatgga tattttgtgc agacaatagc tggatcacgg ttcctaataa ttcttcgttt
    13081 tcttttaaaa gcttgatttt atcaggatct tccaaagtat atccagcttc tgtcaagatc
    13141 gttcgagcag ctagatcatt tgttgtagag ataacgatga aatcttgcgc tgtttggttc
    13201 aattcagcca ttgtacattg tttgatgatc tttccttgat tgatcaggat cagctcatcg
    13261 accatttttt caagctcgct gagtaagtga ctggagatca agaaagaggt gccctgagta
    13321 gccaagtcgg taatgatttt tcgcacatct cttgttgctt gtggatccaa accgttcatc
    13381 ggctcatcta aaataacgat agacggatgg ttcagtaagg caagagcaat tcccaatttt
    13441 tgtttcattc ccaacgagta ggatttcgct tttttgtgaa tgtacttttc catcttgagc
    13501 tgattcacga tagtgtcgat agcagataca tcgttggttt cagagaataa cttcagatga
    13561 tcatagcctg ttaagaatgg atagataccc gggtattcga tcaatgctcc tacttgttcc
    13621 aaccctttat gactagaggg agaaatctca ttttcaccaa tacagattgt tccatctgag
    13681 taatggatca gtcctaaaat agctttcatg atcgttgttt ttccagcgcc attaggacct
    13741 actaatccaa cgattttgcc aggggataag ctaaaactga catcgctgag ggcttgtttg
    13801 tgaccaaagt tcttggataa ttcttggacc gaaagacttt tcaaaaatat tcactccttt
    13861 tctatagata gtacaagcat acacctgatg agtggagaag tcgctaggtc attggactta
    13921 tttcttattt tttcataaaa aaattgaata ttaaataaaa aggcttattt tttctgatca
    13981 gtacttattc caagtgtcta gtggccgcta gtaatcttga tgccaatgat actgatgagt
    14041 agcatcccca caaagaacca agtggaaaga ttcagcttat catgaaacaa gaccacacca
    14101 attatgaccg aaccaactgc gccaatccct gtccagatag gataagagag actcatcggc
    14161 aaacttttga ttgcctttga caaaaagtaa aaactagcaa tcatgccaat cactgtgtaa
    14221 aaagaataat tgattttaga aaaaccatca ctccatttca tcatcgttga ccagaatact
    14281 tccaaaattc ctgctatgat taattccatc catgccatac ttacattcct ccttaactat
    14341 aaaaaaatac acaaaaagag gaaaatcatc ccttcaaaga cctaatggaa tgatcatcct
    14401 ctttatccta cccggtggca gattgtatat ctttttctgt agtatagcac acctatccag
    14461 atatcggcaa tctcatactt tttagtaaag tgtaccaagc actgacggat atatcgttag
    14521 cggaaaagaa gatgaatgct ttgcaatttc atagaaagaa gttgttattt attaatcatt
    14581 taaaaaaaac agtaactaga ccttatttct atatattatc gggcaataa
//
LOCUS       DACCVZ010000066        14431 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.069, whole genome shotgun sequence.
ACCESSION   DACCVZ010000066 DACCVZ010000000
VERSION     DACCVZ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14431
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.069"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(101..796)
                     /locus_tag="IVW63_002072"
     CDS             complement(101..796)
                     /locus_tag="IVW63_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HAP7860337.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(886..1986)
                     /gene="ychF"
                     /locus_tag="IVW63_002073"
     CDS             complement(886..1986)
                     /gene="ychF"
                     /locus_tag="IVW63_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAP7860338.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(1995..2186)
                     /locus_tag="IVW63_002074"
     CDS             complement(1995..2186)
                     /locus_tag="IVW63_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAP7860339.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(2207..3097)
                     /locus_tag="IVW63_002075"
     CDS             complement(2207..3097)
                     /locus_tag="IVW63_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAP7860340.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(3084..3851)
                     /locus_tag="IVW63_002076"
     CDS             complement(3084..3851)
                     /locus_tag="IVW63_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP7860341.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(3863..4576)
                     /gene="rsmG"
                     /locus_tag="IVW63_002077"
     CDS             complement(3863..4576)
                     /gene="rsmG"
                     /locus_tag="IVW63_002077"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAP7860342.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(4808..6709)
                     /gene="mnmG"
                     /locus_tag="IVW63_002078"
     CDS             complement(4808..6709)
                     /gene="mnmG"
                     /locus_tag="IVW63_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAP7860343.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(6726..8123)
                     /gene="mnmE"
                     /locus_tag="IVW63_002079"
     CDS             complement(6726..8123)
                     /gene="mnmE"
                     /locus_tag="IVW63_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAP7860344.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            8467..8805
                     /locus_tag="IVW63_002080"
     CDS             8467..8805
                     /locus_tag="IVW63_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860345.1"
                     /translation="MSPFRSAALEEESDPRINDVVLSTGNINQKYIVRDIVFVVECLE
                     ADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQKKRDGKYFLELFAYGT
                     VIQFIQTTIG"
     gene            complement(8973..9731)
                     /locus_tag="IVW63_002081"
     CDS             complement(8973..9731)
                     /locus_tag="IVW63_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAP7860346.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(9749..10567)
                     /locus_tag="IVW63_002082"
     CDS             complement(9749..10567)
                     /locus_tag="IVW63_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAP7860347.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(10564..10920)
                     /gene="rnpA"
                     /locus_tag="IVW63_002083"
     CDS             complement(10564..10920)
                     /gene="rnpA"
                     /locus_tag="IVW63_002083"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAP7860348.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(11038..11172)
                     /gene="rpmH"
                     /locus_tag="IVW63_002084"
     CDS             complement(11038..11172)
                     /gene="rpmH"
                     /locus_tag="IVW63_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAP7860349.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            11696..13030
                     /gene="dnaA"
                     /locus_tag="IVW63_002085"
     CDS             11696..13030
                     /gene="dnaA"
                     /locus_tag="IVW63_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAP7860350.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            13228..14358
                     /gene="dnaN"
                     /locus_tag="IVW63_002086"
     CDS             13228..14358
                     /gene="dnaN"
                     /locus_tag="IVW63_002086"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAP7860351.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
BASE COUNT         4000 a         3042 c         2583 g         4806 t
ORIGIN      
        1 ttttgtcaca gtcccttact attatttaac tatggataaa caaaatgagg ttctttacta
       61 cccctagata tctagcaaaa tagctgatct ttttgctagt ttatcttctt gggacggata
      121 aacttccaat aatcccgtat tttttcttca agtagtaacg gattgctaaa gcagttgccc
      181 cgataatgat aactactact ggatctaata ctggattgat aactggtggc aatagtgttg
      241 tcgcagaaaa cagtacgacc caaagaagtg tcgttccacc taggataagc aatgtcttac
      301 ccattcctgg tttcttgctt cgatctgctc cgggatattc atattgatag atgtatttgt
      361 acatcatata aaagacccag ccaccgattg cagaacctag aacgagtgta gaaaagccat
      421 aagctggcgt tgttccacgt gaaaacaatc cggtaatcgc aatcatgata cttaatagac
      481 caagcaacag caacgtatta tctaaccaca tcaataaagg ggtggatgaa ttttttactt
      541 ctgctggctt attgatgatt gcttccgttc tttcagagac tgtcccaaac aattgacggg
      601 ctgttcttcc gcctttttgt tctgcaacta aagtaggcag aatgtcatga agggctttta
      661 ctttttcttc ttcagacaaa ttcgctgctt ctaaagattt tttcaaatca aaaatgtact
      721 gttgatttct tttggttaat tttgtttcta aactattgtt ttcttttacg attgctcgta
      781 attgttctgg ttccattatc taatagtcct ccttagccgt tccttttctc aacggtcgtc
      841 acaaaagaca ttctaccata ttctacagct agtttgatag cccttttaca cattaaagcg
      901 gaataacatt acgtcgccgt cttgtacgac ataatctttt ccttctaatc gaacacgtcc
      961 agcttctttt gctgcatgca tgtttccgta atgatccaag tcttcaaaag agacagtttc
     1021 tgcacggata aatccgcgtt cgaaatctga atggatgatt cctgctgctt gtggtgcttt
     1081 gattcctttt ttgaatgtcc aagcacgtac ttcttgttcc ccagcagtaa agtaagtagc
     1141 taagcctaac aaatcataag cagcacggat caactgatcc aaacctgatt cttcgattcc
     1201 taaagcttct aaaaattccg ctttgtcttc ttcatctaat tctgcgattt cttcttctgc
     1261 acgagcactg accacgatca cttctgcatt ttcttctgca gcaaagttgc gcacttcttg
     1321 tacataatga ttcgcgtctg catctgctac gtcatcttct gagacattgg ctacataaag
     1381 aattggtttt gtcgtcaata aaaatagtga tttaacgatt ttttgttctt cttcagtaaa
     1441 ttcgatcgtt cgggcagatt ttccttcttc cagtacaggt ttgattttat ccagtacagc
     1501 tagttctgcc actgcatctt tatctttggt tttagcaact tttgctacac gagtatagcg
     1561 tttgttgata gattctaagt ctgctaacac tagttccaag ttgatcgtat caatatcttc
     1621 tagtggatca acacgtcctt ctacgtgagt aatattatca tcatcaaaac agcgaacaac
     1681 gtgacaaata gcgtctactt ggcggatatg gcttaagaat tgatttccca aaccttctcc
     1741 tttacttgcg ccttttacga ttccagcaat atctgtaaat tcaaaagtcg tcggaacagt
     1801 ttttttcgga tgtacaagtt ctgttaagcg ttgcaaacgc cagtcaggta cttctaccat
     1861 ccctacgttg gggtcgatcg tcgcaaaggg atagtttgct gcttctgctc ctgcttttgt
     1921 gatcgcatta aacaaagttg attttcctac gttgggcaac ccaacaattc cagcagtcaa
     1981 tgccataaat ttattcactc tttctctgca tttttttcaa ttactttttt taatttcttt
     2041 tcaaaatctc gacgggtcat catgacgata tgtccgcaat tcatacatct gattttgata
     2101 tctgcgccca ttcgaatgac ttcccagcga ttcgtctggc aagcgtgagg ttttttcatt
     2161 tcaacgatat cgtgcaagtc gtacataaaa atagcctcct ttttgtttat tcttcatcaa
     2221 attgaatatt caagatatca agaattcgag tcaaatcttt ttgagaaaga tattcaatct
     2281 cgatcttacc tttcccattt ttttcttgga tagctacact tgtaccaaat ttatccatca
     2341 aacgatcttc gctttctcgg atataatatg gtttttcctt tgctagcctt gggatttttt
     2401 tcttttcttt tccatcattt tgatttaact cagaaacaag ctgttccagt tggcggacag
     2461 ttaaattttc agttactgca cgattggcta atttcaagat caatgtttta ttttttaaac
     2521 ctaacagcgt acgggcttgt cccatagata aacgctgatc ttgtaccatt tccttgacaa
     2581 gatccggtaa agaaagcaag cgcaaataat tggcgatata aggtctgctc tttcctaaac
     2641 gactagctac ttctgcttgt gttagtttca ggtttttcat cagcatctca tatgcttctg
     2701 cttcttctaa cggattcaga tcttctcgct gcaagttttc cagcactgct acttgcatca
     2761 tcgcttcttc gtcaaagtct ctaacgatag cagggatcgt ttctttttca gctagtttgg
     2821 acgctcgaaa acgtcgctcc cctgcaataa tctcatatcc ttttactgcg gaacggcgta
     2881 cgatgatggg ttgaaagaca cctgattgtt caatagaatt agctagttcc tgcaaagata
     2941 cttcttcaaa tgttttacgg ggctgatacg gatttggtcg cagctcattc aatggtagct
     3001 ggacaacggt atcatctttt acatccaccg tctctaagtt ttctaaatct tgaaacagtg
     3061 catcgattcc tcggcctaat cctttacttt tcttcacgac ttaccacttc ctttgccaat
     3121 gcttggtaga cttcagctcc tcgagaacgt ggatcgtagt cgatgatcgg ttttccatga
     3181 ctaggtgctt ctgataaacg aatatttctt ggaatgatcg tttcgtaaac tttttcgcgg
     3241 aagtatttac gtacttcttc tacgacttca tttcccagat ttgttcgtgc atcatacatt
     3301 gtcagtaaga ctccctcgat ctctaattct ggattaaagt gtttttggac taaacgaacc
     3361 gtattcagta attggcttaa tccttccaat gcgtaatact cacactgaac aggtatcaaa
     3421 atcgaatcac ttgctgtaaa tgaattgatt gtcagatggc caagagaagg cgggcaatcg
     3481 atcaaaatat aatcatactg actgcttact tctgctaaag atccttttaa tcttgattct
     3541 cttgccatca ttgacgtcaa ttcgatctct gctcctgcta attggagagt cgcaggcaca
     3601 atactcaaat tttcgtgttc agtgatcaaa gttgcctcat caattggcaa ttcattgact
     3661 agaacatcat agatgtctct tgtcacatca ggttttctga tcccgacacc actggtagca
     3721 tttccttgtg catccatatc cactagcaat acttttttgc caaggctagc aagacaagca
     3781 cctagattca ccgtcgtcgt tgttttgccg acgccacctt tttggttcgc aacagatatt
     3841 atttgtgcca tctcttctcc tcctatttga ttggctgctt attaggcagt ccgggctttc
     3901 ttgggtattt ctttggggtt ggtttctttt tttgaataac gatgatatgc cgttgatcag
     3961 agacattcgg caaggtaacc gcctcttctt tgaggaattt accacctaat aaagcaatcg
     4021 cttgttttgc ttctgtcaat tcctcttcac tttttgctgc tttcaatgca taaaaatagc
     4081 cttcttgttt agccaagggc aaacacaatt ccgctaacac attcaaacga gcaaccgcac
     4141 gagcagtgac aaggtcaaat gatgcacgaa agtgaggatt ttgcccaaat gtttctgccc
     4201 ggtcatgata taaggaagca tcgattccta ataatcgggt taactcagat aagaaggtta
     4261 ttcgtttatt cagagaatca acgatcgtta tctgcagttc tggaaaggca atttttaaag
     4321 gtatgctagg aaaccctgcc cccgaaccaa catcgcataa agataaaggt tgcgtaaagt
     4381 ctacttcaaa tgctaatgta agtgaatcgt aaaaatgctt cagatatacg tctttttcat
     4441 ccgtaatagc tgtaaggttc atcttttcgt tccattcgac taatgtccga taataaatag
     4501 cgaattgatt catttgatga tcggtaagct ctatcccttt ttctgccaag gattggcgaa
     4561 attcttctgg tatcataaat attcctttca ttgtgaaaca gcaattgttt cacagattct
     4621 ctccctactt taacgcaaaa tctctagaca tgcaatcctt ccatatggat tcttaaaaat
     4681 ttgaaaagta agaaaagccg atagactttt tctttctagt atgactcata aaatatacac
     4741 agaagagaga actagctttg agcaatttct gcaaaaacta gttctctctt ctatttatta
     4801 ttacgtatta cgctggttca ctgactttcg caatcttccc ttgttcgata tagaccatta
     4861 ggatacttag gtctgcaggg tttacgccac tgattcggct agcttgggca attgtttctg
     4921 gttggatttt ctgcaatttt tgttttgctt ctgttgctaa tccgttgatt gctgcgtagt
     4981 cgatgttttc tggaatcttt ttcgcttcca tgcgttttaa tttttctact ttttccatgg
     5041 cttttttgat gtagccttca tatttgattt ggatttctac ttgttcgatt tcttttcgtg
     5101 tcaattcttc attttctgga ataaaccgta gaagttctgc ataagtaatc tcaggacgtc
     5161 ttaaaaagtc gcttgctagt acaccatctt ttaatggtgc cgcattaatc gttgctaaaa
     5221 agtcttggac ttcttctgtt ggtttgattc gtacattcat caaacgtttg atttcttgtt
     5281 caactgcttc ttttttcttc aaataattct tgtattgatc ttcttttact aagcctacac
     5341 ggtgacccat ttctgttaat cgcaaatctg cattatcatg acgtaaaagc agacggtatt
     5401 cagcacgtga agtcagcaaa cgataaggtt cgttcgttcc ttttgttacc aaatcatcga
     5461 tcatgacacc gatgtaaccg tcacttcgtt tgatcactaa aggttctttt ccctgaactt
     5521 tcaaagctgc attgataccg gcaatcagcc cttgtccagc cgcttcttca taaccgcttg
     5581 taccatttgt ttgtccagct gtataaagat tttcaacgac tttagtttct aatgtcggac
     5641 ggagctggtg tggctctact acgtcatatt cgatagcata tcctgtacgc atcatttcta
     5701 ctttttctaa tccagcaata gaatgaagca tgttgacttg aacatcctct ggtaaagaag
     5761 tagataaacc ttgaacatag acttcttccg tatttaagcc ttctggttcc aaaaataatt
     5821 gatgacgtgg tttgtctgca aaacgcacga tcttatcttc gatggatgga caatagcgag
     5881 cgcctacccc ttcaacgatc cctgtaaaca ttggggcacg atgtaagttg tctcgaataa
     5941 tttggtgagt cgtctcacct gtataggtca gccagcaaga ttcctgatct agtttatagg
     6001 cactatctgg tgtgctgaag ctaaaatgat tcggctcttt gtcaccaggc tgctcttctg
     6061 taacagaata gtcgatcgta cttgatttta ctcgaggcgg tgttcctgtt ttgaaccgtt
     6121 cgatagcaaa gccaagttct tttagatgat tcgctagtcc aatagaaggt tgagagttat
     6181 tcggacctga tgaatatttc aattcaccga taatgatttc tccgcgaagt gctgttccgg
     6241 ctgtaataac aactgctttg gcccggtagc tcgctcctgt ggacgtcact actccatgac
     6301 aaacaccatc ttcgacgatc agttcttcga cgattccttg tcttagcgtc aaatttggtt
     6361 ctttttcgat cgtatgtttc atttctgttg aataagcatg tttgtctgct tgtgctcgca
     6421 atgctcggac agctgggcct tttcctgtgt tcaacatacg catttggata taggttttat
     6481 cgatattctt acccatttct ccgcctaacg catcgatttc tcgaacgaca acgcctttag
     6541 ctggtccgcc tacagaagga ttacatggca tgaatgctac catgtccaaa tttattgtca
     6601 gtaataatgt ttttgatccc atacgtgcag cagcaagtgc agcttctgaa ccggcgtgtc
     6661 ctgcgccaac aacgatcacg tcatacgcat ctgcttcata atgttccaat cgtttgttcc
     6721 tccttttatt ttcctaaaca aaattgactg aataattgag tgattagctc atcttgtaca
     6781 ctgtcgccga caacttctcc tagatagtcc cagcaacgcg tcatatctat ttgaacgaga
     6841 tccacaggca ttcctgaatc aatacctgca atgacttctt caagtgagag ggaagctttt
     6901 tctaacaacg cgatatggcg ggtattagaa acataagtag cgtctctttc tcctgtttct
     6961 ccgctgaaga ataaatcaga aatagctgat tccaaacgat ctagtccgtc gtttttagct
     7021 acggaaattg aaaaaactgg ttcattttcg atcaatttct tcaatttttc ttgttccagc
     7081 tgtgctggca aatctgtttt atttagaaga atgatccgtt tcaatccact tgtcgcttcc
     7141 aataattgtt catcttctgc tgtcagtggt tcgctttggt ttagaacaag taagatcaag
     7201 tctgcttctg ctaatgcttt tcggcttctt tcgaccccga tccgttccac cacatcttct
     7261 gtttcccgaa ttccagctgt atcgattagc ttgagcggta ccccccgaac attgacatac
     7321 tcttcgatta catctcgagt cgttcctgca atatccgtaa cgattgcttt ttcttctctt
     7381 aacaaatggt ttaacaaact tgatttgccg acatttggcc ggccgatgat tgccgtactt
     7441 aacccttccc gcagaacctt cccttgcttg gatgtagcaa gtagcgcttg gattctttgt
     7501 tggatcatct gcgctttttc aagcaataac ttcgtagtca attcttcgac atcatcatat
     7561 tctggataat caatatttac ttctacttgt gctaatgtct ctaaaatctc ttgtctcaat
     7621 gagcggatca aagcagacag attgccgtct aactgattaa gagctagtcc cattgctttg
     7681 tctgtttttg cccgaatcaa atccatcaca gcttctgcct gtgaaaggtc aacacgacca
     7741 ttcaagaatg ctcgttttgt gaattcgcct ggctcagcta atcttgcacc ttctcttaac
     7801 aatagctgca aaatttgatt gactacaacg atcccaccgt gacaattgat ttctactaca
     7861 tcttcccgcg taaatgtctt tggtgctctc atcacggaga ccatgacttc atcgacaagc
     7921 tgattgctct tgggatcaac gatatgtcca taatggatcg tatgacttgg tacttctgat
     7981 aatcgtttgt ttccagattg ataaacttta tctgctagtt gcacagcttg atcgccactt
     8041 aaacgaacga tactgattgc accttctcca ggtggggtag aaattgccgc aatcgtatca
     8101 aattctaaag taatttcagc cattttttca cttccttttt cattttgcgc acaaaaaaag
     8161 tgcccactcc accctttatg cacaataaac ggtgaacttc gcactttgac tgcttgttct
     8221 tgattaaatt ctggtcatag attatcacac ttgctataag gaatcaagtg tttaaaacaa
     8281 ttagatgaag ttgagcctgt tctgcttcca ttaccttata tttaattgtc cttggatgtc
     8341 tctttgcgtt ctttggttta ttcgaagaga agatactgta taaacaaggc tttatctttc
     8401 ttaaaaaaaa cggtacacta aatggtagcg ctatctaaac tatacacttt tgaaaggaga
     8461 aaatatgtga gcccgttcag atctgctgca ttggaagaag aaagtgaccc tcggatcaac
     8521 gatgtcgttt tatctacagg gaatatcaac cagaaatata tcgtccgcga tatcgttttt
     8581 gttgtggaat gcttagaagc tgatttgttt gacccatctt ttcccaaaga tgaccttttc
     8641 ttaacaacga agaggaaatt aaagacgaag gtacttgaat atggtgcgaa tgcagtaatc
     8701 aactgtcatt ttgagtatca gcaaaaaaaa cgcgacggaa agtattttct ggaacttttt
     8761 gcttatggaa cagtgatcca atttatccaa acaacgattg gttaaatgaa acagacaaaa
     8821 aaagcggatc aaaactgaag acagtttcga tccgcttttt tctatcaaag ttagtgacta
     8881 cttcatcgta tactctgata agaatgattt ctagtaaaat atacttggtt tgaaaaactt
     8941 tgtcaacgtg atttattcaa aaagtaatgg aatcaataat attttttagc aggttctact
     9001 actaaataac gataaggttc ctcaccttcc gaatgtgttt ttacatgttc atctttgctt
     9061 aatgcagcat ggatttgttt acgttcaaat gcaggcattg gttctaagaa aacaggctgc
     9121 cctgtccgtt ttactttttc agccgtgcga tcagctaaac gctgaatgat ctcttggcgc
     9181 ttttcacggt aattgcctac attgactact acagacagct tatttcttgc taaacgatgg
     9241 atgaagactt gtgccagata ttgcaatgca ttcagtgttt ttccatgttt cccaatcagt
     9301 atgccttgct tttgtgtttc taaatggaaa acaaccatat tatttgattc tctttccatt
     9361 ttgacaagag ctggagcatc aagctgtttt gaaatttcag taagataaac tgccaattcc
     9421 gttaaagctg cttcatcacc tagctcactt acttcttctg ttttttcttc aagaatcgtt
     9481 tcgttgacta cctcgatctc agctgttggt tcttcttcca aaatttcttc tacagtctgt
     9541 tctactgttt cagaaacttt ttcgctgata cttggctgga tcgaaagccg tgcattcttt
     9601 cgacccattc ctaggaaacc tttttttcct tcttccagta tttcgatttc gacttggtct
     9661 ttggccaaac ccaaatcagc cagacctagt tggacagctt cgtctattgt tgcagcttca
     9721 taaatcggca ttagcattac ctcccctatt atttccgttt tttcttagga ttcattgctt
     9781 tcttaagagc acgttctctt tcgcggattc tccgtgcttc ttcttcacgc tcttttcgaa
     9841 ttttgaaagg gttgttgatc agcagcgttt gtacaacttg gaaggcattg gaaactaccc
     9901 agtataatga aagaccgctg gctaaattga cacccatcac taaaatcatt acaggcatca
     9961 cgaaattcat gatcttcatt gatgcattcg attcaatttg actcatgcta gataaatacg
    10021 tacttgcaaa agtaaagatt gctgctaaaa tcggcaaaat aaatgttgga tccgcgttcc
    10081 ctaagttcaa ccataagaaa tgcccttgtt tcaactctgg tacacgtgaa atagattgcc
    10141 ataacgccat caagattggc atttgtacta ataaaggaag acaaccagca tatggattga
    10201 cgccattttc tgcatataaa cgctgctgct cttctcttaa cttactttgt gtttccggat
    10261 ctcttgaact atattgttgc tgcagtgctt ttaatttcgg ttgtaattct tgcgttttac
    10321 gcatgctctt tgtttggaaa tgcatcaacg gcaataggat cacgcggatg atcagtgtaa
    10381 ataaaatgat ccctatccct gcattaccaa atgacaacgc cttgatcgcc tcagcaaagt
    10441 aataaacaat ataacgatcc caaattcctg tactctgtgc gctgacttcc ccagttccgc
    10501 aaccggataa gacgatgacc aaactaacga taccggccat caaaagtaaa cgtttgtatt
    10561 tcttcactta ctcttttcct ctctgtcgat tatttttgca agttttaaga cgtggactaa
    10621 attggagcga acctcatcat aagtcaaccc cttcacactt ggtctagcaa tcacaataaa
    10681 atccaactcc ggatcaattt cttcttttat agaataaact gctgctcgga tttttcgttt
    10741 gacttcattg cggtttaccg cgttgccgac cttttttcct acagataaac caactcgaaa
    10801 atgaggctgt cccggttttt ccaaacggta aacgacgaat ttgcggttag caaaagaatc
    10861 tcccgtatgg aacacggctt gaaactctcg ttcttttttt actcgatacg cttttctcat
    10921 tagttttctt tccttttcta tctctcactt acgctcataa tcataccata attacgattg
    10981 tcctttcatc atttccctaa aaaagagtat aaaaaaaacc actgaaaccc cagtggccta
    11041 agctgaaaga acttttcttc ctttgcgacg acggctagct aacacacgac gtccattttt
    11101 agtactcata cgtttacgga atccgtgaac tttttgacgt ttacgtttat ttggttggta
    11161 tgttcttttc atatattcca cctccaaaat gttcttatct attttataaa cacagacata
    11221 ctttgatagt ataacgacaa agtagtgatt ttgtcaatat aaaatagaag atcgattgtt
    11281 aaaacttatc cacaagatta tttttttcta tgggagtcct atgtggaaaa agttatgcac
    11341 agggattatc cacagataat aaatggctgg ttttacacag aaaacacacg tgtaaaaaaa
    11401 gtaatccaca atcaggtgat ttcctgtgta ttccgtctcc taactattgg tatatctata
    11461 ttttttatcc acagatgcaa gaggaaatct attgattttt acgagttttc cacctgtgca
    11521 ttagtggtgt ggaaaacttt tttttgacaa ctgtgttttt ctcttttttc tttttgtcga
    11581 ttgtgtggat aattgtaatt aaaaaatttt tttcttcggt ttctgtggaa aactattgaa
    11641 aaaaatgcta aattagtact agttattcac tttttaatga aggaggaggc cttatatggt
    11701 atccctcgat gctttatgga atgaattaaa agcaacatac caaaaggatt tatcgcctgc
    11761 tagctataat acatggatcg aaacagcgaa ccctcgaacc cttgatcaaa accagctcgt
    11821 tgttgaggtt cctagcaaga ttcataaaga atattgggaa aaaaacctgg cgacaaaaat
    11881 cgttgaagtc ggttatatgt tatcaggaaa tgagattatc cctcgcttta ttactggcga
    11941 agaagcagag caagaagaag ttatagaaga aaaaaatcca aaagttgtgg cacctagtcc
    12001 gctaaaaaaa gccatgctga accctaaata tacctttgat acgtttgtca ttggtaaagg
    12061 aaaccagatg gctcatgcag cagcgctcgt tgtagcagaa gatccaggtt ctatttataa
    12121 cccgctcttc ttttatggag gcgtgggact tggtaagact cacttgatgc atgcaattgg
    12181 tcatcaaatg ctgcaaagtc agcctaatgc caaagtaaaa tatgtaagca gtgaaacttt
    12241 tgctaatgat ttcatcaatt cgatccaaaa caaaacagca gaagagttcc gtcaagaata
    12301 tcgaaatgtt gatttactgc tagtggatga cattcaattt tttgcagaaa aagaagctac
    12361 gcaagaagag tttttccata ctttcaatgc cttgtacaat gaagggaaac aaatcgtact
    12421 aaccagtgat cggttgccaa acgagattcc gaaactgcaa gaacgcctcg tttctcgctt
    12481 tgcatggggg ctgtctgttg atattacacc gccggatctt gaaacaagaa cagcgatttt
    12541 acgtaaaaaa gcggcggctg aacgtctaga gatcccagat gacacactaa gctacatcgc
    12601 aggacaaatt gattctaaca ttcgtgaatt agaaggtgcg cttgttcgag tgcaagcttt
    12661 tgctgcgatg aatagtgaag atatttcgac tagtctagct gcagacgcac tgaaaacgtt
    12721 aaaatcagga aaaggacatc ctcaattgtc aatcctgcag atccaagaag aagtggcaaa
    12781 gtattatcac atccaattga aagatatcaa aggaaagaaa cgcgtcaaat ctattgttgt
    12841 tcctagacaa atcgctatgt atttggcacg tgagctcaca gataattctt taccgaaaat
    12901 cggagctgaa ttcggtggca aggatcatac aacggttatc catgctcatg aaaaaatcca
    12961 gcagctgatg gattctagtg tcagtatgca aaatgaagta tcagaaatca aaaacttttt
    13021 actaaattaa tttgtcgatt ctatcaactg aaaatagcat gtggataaaa gaaaaaaacg
    13081 ttcaaaagtt atgcacactt tttccacagc tgttttttcg tttctctctt acgttttttg
    13141 agttttccac agaatcaaca tgccctatta cttttattat tctttttaac taataataaa
    13201 taaacaaaca ttcaaaggag atacatcatg aaagttactt taaaccgagc tagctttatg
    13261 caggaattgc aaactgttca acgagctatt tcaagcaaaa ccacgatccc tattttgaca
    13321 ggtgtaaaaa tcacactgac acaagaaggt ttgactttga cggggagcaa cgctgatata
    13381 tcaattgaaa cttttttgtc tgttgaaaac gaaaaagcaa atatgcaaat cgaatctact
    13441 ggttccattg ttttacaagc acgtttcttt agcgaaatca ttcggagact tcctgaagaa
    13501 acatttactt tagaagtttt agaaaataaa caagtagcga ttacttctgg aaaagcgaat
    13561 tttatcgtaa atggattaga tgcagataac tatcctcatc ttcctgttgt cgaaagccat
    13621 aaccagatga aattacctgt acacgtattg actaaactaa tcaacgaaac agtttttgct
    13681 gtctcacaac atgagagtcg tccaatcttg acaggtgtgc atttcatttt atctgataat
    13741 tctttattgg ctgtagctac tgattctcac cgtctaagtc aacgcgtgat tccagtagaa
    13801 caagcggctg atcattttga tattgttatt cctggaaaaa gtttgatcga attatctcgc
    13861 tcattaacaa atgaagaaga aatcgtcgaa atcagcatta tggaaaacca agtgttgttc
    13921 aaaacagaaa cgatgtattt ctattcccgt ttgctagaag gaaactatcc tgataccaat
    13981 cgtttgattc cttcaagttt taatacagag gttgaatttt ctgttcctag ctttttagcg
    14041 gcgatcgaac gggcttcttt actttctcat gaaggccgta acaacatcgt tcgtttatct
    14101 attcgtccag atgcggttgt tttatacgga aattcgccag aaatcgggaa agtagaagaa
    14161 agcttgagtt atacagcaag cagtggcgat ccattagata tttctttcaa tccggattat
    14221 atgaaagcag cgttgcgtgc atttggagat atgagcatca aagtgaaatt tatctctgct
    14281 attcgtccat ttacattgga accaacggaa gatggcgttc aatttattca gctgattact
    14341 cctgtacgta caaattaaca atgattttca ttgttcttga aaatttaatt gaaaagaaat
    14401 agaaaaaata aaattttaaa cagaaggccc t
//
LOCUS       DACCVZ010000067        13750 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.070, whole genome shotgun sequence.
ACCESSION   DACCVZ010000067 DACCVZ010000000
VERSION     DACCVZ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13750
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.070"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            149..1576
                     /locus_tag="IVW63_002087"
     CDS             149..1576
                     /locus_tag="IVW63_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP7860352.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1668..2033)
                     /locus_tag="IVW63_002088"
     CDS             complement(1668..2033)
                     /locus_tag="IVW63_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAP7860353.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(2030..2395)
                     /locus_tag="IVW63_002089"
     CDS             complement(2030..2395)
                     /locus_tag="IVW63_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAP7860354.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2587..2835)
                     /locus_tag="IVW63_002090"
     CDS             complement(2587..2835)
                     /locus_tag="IVW63_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860355.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2834..2962
                     /locus_tag="IVW63_002091"
     CDS             2834..2962
                     /locus_tag="IVW63_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HAP7860356.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            3019..4713
                     /locus_tag="IVW63_002092"
     CDS             3019..4713
                     /locus_tag="IVW63_002092"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HAP7860357.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4717..4836
                     /locus_tag="IVW63_002093"
                     /pseudo
     CDS             4717..4836
                     /locus_tag="IVW63_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4918..5109
                     /locus_tag="IVW63_002094"
     CDS             4918..5109
                     /locus_tag="IVW63_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860358.1"
                     /translation="MDLLPQMQAFEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDL
                     LPQMQAFEHRLPRGYEKGV"
     gene            5487..6620
                     /locus_tag="IVW63_002095"
     CDS             5487..6620
                     /locus_tag="IVW63_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAP7860359.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6651..6971
                     /locus_tag="IVW63_002096"
     CDS             6651..6971
                     /locus_tag="IVW63_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860360.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(7000..7464)
                     /locus_tag="IVW63_002097"
     CDS             complement(7000..7464)
                     /locus_tag="IVW63_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7860361.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7595..8848)
                     /locus_tag="IVW63_002098"
     CDS             complement(7595..8848)
                     /locus_tag="IVW63_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7860362.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8877..9194)
                     /locus_tag="IVW63_002099"
     CDS             complement(8877..9194)
                     /locus_tag="IVW63_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP7860363.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(9220..9540)
                     /locus_tag="IVW63_002100"
     CDS             complement(9220..9540)
                     /locus_tag="IVW63_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7860364.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(10004..11419)
                     /locus_tag="IVW63_002101"
     CDS             complement(10004..11419)
                     /locus_tag="IVW63_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP7860365.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11436..12752)
                     /locus_tag="IVW63_002102"
     CDS             complement(11436..12752)
                     /locus_tag="IVW63_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7860366.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12902..13600)
                     /locus_tag="IVW63_002103"
     CDS             complement(12902..13600)
                     /locus_tag="IVW63_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAP7860367.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
BASE COUNT         4369 a         2790 c         2360 g         4231 t
ORIGIN      
        1 attatctgtt ttccaaattt tataacataa aaaacctttt ttaacggcat ttatatgctt
       61 tttcagaaat taactgatga tttcaaaaag aaaacatgtc ataatatttc ccatattgtg
      121 caaaaaaata caaggcggag gctctactat gattgaagaa tatattgaga aaaatatttt
      181 aagacagctg tttttatgtg ggcaattcta tgtaaataaa gaagtcaatc tagaaaagct
      241 ctccaatctc ctgcatgttt gcaaaaccac tttactcaat gatatcaata acataaaaaa
      301 agaatttgaa gaacagatcg cttatacaca tcgggaaaag gaccgttaca ctttatattt
      361 ttcagaacat atacctcgat gcaagatcat gcagcaattg tctcaaaatt cgttgttttt
      421 aaaaacttgt ctgctttatt tggaagaaga tgaacctgat tatcttcaat taactgaatg
      481 tgaattcatc tctgtcagca aagcttattc attaaaaaaa caagtattag cttattttaa
      541 tgactgcggg atcgaaatcg accgctactc ccctcgattc actgaaatgg aaagacgtct
      601 gctgcttctt aatgtgtcgt atcgtttagg cggttttaat tcttgggagc tacctgaatc
      661 gttttttgaa cgtgccgatc gtttcattga atccgtaacg gaaaatagtg gcagatttta
      721 tgataaagaa aataaagaaa tcttatcgat tggttttgct atcagtttcc tacgccagca
      781 agtgtgtgct gtgacaatag attcaaaatt tatcgaagaa atcaaaaaac gtcctattta
      841 caattatgtc gaatcagcat gggaaaacac tgatttccaa acctattata aaaaagaaga
      901 attcgccttt attttgacac tattcaatct ttgtaattat ggtttccatt cttatcagtt
      961 gattgcggaa gactttcaac agctacacca agtgtttatt gacaatactc ccgaaataaa
     1021 agaactagtt gctacctttg aatctcactt caatcaagaa ttattcggaa accaaccgtt
     1081 cgaacgtgcg ctgattcatc tgatgcgttc ggcttgggat aactatcaat tattcatgcc
     1141 agaaaaattt tatcttttaa atgaggaaca gacaaattta tataaagaag tccagacaat
     1201 tttttccagc tggtccagcc agttacctta tgatctacgg ttgaatccta attgcatgcg
     1261 ggcttttgtg atcgaattga gcggaattct ccgtctgaca aaagaacatc tgactatcta
     1321 tatcgtcaca aattcggatg ttcattatct gatttatcgg gaagccttgg aagctgtaac
     1381 tactttcgat tttcaagttg caccaacaat ttattcaagt atatctgata taaagaagta
     1441 tgcgcagcag tcctcaaacc gggtattatg tgaacgtaca ttatatacac cagatgcggt
     1501 ccaatatgaa aatattattc ctatttcgat caatacgatc gatcgagcta tcatttcagc
     1561 tgtgcaaaac aaataagggg ctgtgacaaa aatcatgtca cagcctctta tttgttgaag
     1621 atgcccattt ctgtaacaat ctcttgatac acgtcaggct cacaacctca cttattttgg
     1681 acatctacgg gtccgatctc tttatttaaa aaataagaaa tgatggttcg gataactacc
     1741 aacgccgcta gttggaaaat atcctgcaag gtaggtttga taatcgattc gatgatccca
     1801 gctgaaacaa gaatttccaa acttagaagt atatagcctc ccaacatctt tttaatagca
     1861 ttgttctcgc tgactcggtc gctttgcact tttgtatgga caaataaata tttcaaaaaa
     1921 tccttgattg atagacaaac accccaaacc aataaacaga tagcaaagat atcaagtccc
     1981 agtacaagtt tttcgaaata tggaagaaga aactgcatca actctgtcgt catcctacct
     2041 ctcctcttct ttgtttttct ttgtcttcta tttcctgatt caagaaataa gaaatgactg
     2101 ttcgaatgat aataataagt gcaagcttca aaatatctgt ccaagtcggc ttgataactg
     2161 actcgatgat atcagcaacg actagtactt ccaagcttaa caaaatataa cttgctagca
     2221 gttttcttgt atctgcatta cgagtattac gttctgcata gtttttcttg acatgagacc
     2281 aatcaaaaag tttgaataga acaagaacga tcccgacaat taagataccg atagaacaaa
     2341 tatttaaaat agcaatgatc cattctagaa attcaattaa atttgagcga aacatatacg
     2401 ctacctactt tcttttaatt tgttcctatt cttttattgt aaaagaaagt taccttgttc
     2461 gtctatttaa aagttgttct aatgataacg gttcgcttaa atttttcttt ttcactctcc
     2521 catttttctc cctccatcca taaatcgtgg aagtatccaa aacaacgtag caagttaaaa
     2581 taaggcttag tccgtcatca gcttttcaaa gaagcactgt ctcggtgctt tttttgtacc
     2641 caaatttcta aaaatagaac catacacctc ctcaaatctt ttcttcttac ctaccctatt
     2701 tttatttaca ggaaaatcag acacttcttc ttttttgtca aaatttcctt tttcttctcg
     2761 tcctatcatt tggcattcta ataaaaacga actatccttg gatatagaaa gagaaaacaa
     2821 ggaggcgttt ttcatgagta aaaaattaat caaagtcggc atcggtttag gtttgcttgc
     2881 ccttggcgct gcatatctag gaaaaaagac aggactattc gaagatgaca gtcatttata
     2941 tgatgaattc gaatcaatct agcatcctat ttagttgaat cactacggac atacttggaa
     3001 gacattggag gaatcacaat gagaaaaagt aaagcaataa tgattggtgc cggtattgcc
     3061 aatatggcag cggctgttta tttgattcaa gaaggcaaat ggaaagggga tcagatcacc
     3121 ttttattcat tggatgatca cggttcaaat gatggtgcac cgaccgacac tgtagtggat
     3181 gaatattgga ataaaaacca tccattagaa aaccaaaaag gctatattgc tcgaggcggt
     3241 cgcatgctta attaccgtac ctatgtagat ttgatggatc tgttaagtcg aataccttct
     3301 gttactgagc cagggatgac tgctgaagaa gatacgagag attttgatgc aaaacaccga
     3361 acctttgaca aagcacgttt gatggaaggt ggcaaaggaa tcattgatgg cggaaaactg
     3421 ggattcaata ataaagaccg tattcttctg actaaactga ttgctatgcc tgattcagaa
     3481 gaagaaaaac tagacaatat cactatcgaa gaatatttca aagatgatcc acactttttt
     3541 gaaacaaact tctggtttat gtgggaaaca acatttgctt tcagaacacg tagttctgct
     3601 caagaattgc gtcgctatat gcatcaaatg atttatgaat tcactcaaat cgaacatcta
     3661 gtgggcgtca atcgaacacg ttacaatcaa tacgaaagta ttatgcttcc tttgatcgag
     3721 tacttgaaag aacaaggatg caaaatcatt ttgaaccgcc gtgtcactga ctgggaattc
     3781 aaagaaacac cgatgcaaga tgaaatcact gtgactggtt tgaaaattac caatacactg
     3841 actcaagaag aagaatacgt tgtggtcgat gaagatacag cagttatttt cactaatggg
     3901 tccattacag attcagctac tttaggagat tacgaaacac cagctgtaga aaatatggat
     3961 tatggtgcag cttctagtct ctggaaaaaa gccagtgaac gtttctacaa cttgggaaat
     4021 cctgacaaat tctttgctga tcgagatgca agcgaatggg tcagctttac cctgacgacg
     4081 aaaaaccatt tgttgttgaa tgaaatcacc cgtatcacga ctcaagaacc aggaaatgcc
     4141 ttgaattcat ttatttcaac cacaccgatc acgccgttag gccaaaaaga tgtcaatatg
     4201 tctatcgtcg tgcatcatca accgcatttt acgtctcaga aaccaaatga aacagttatt
     4261 tggggttatt tcctttatcc aagacgacgt ggcgaatttg tggataaaca gtatattaaa
     4321 atgaatggaa aagaaatgct agaagaactg attggacaac tttcaaaagt agatcctgga
     4381 ccagtgaata ttcgtgaaaa agaaacagaa attttcgaca gcgtaataaa taatatccct
     4441 gtctatatgc cttatgcttc cgcgttgttc aataatcgtg ccaaaagcga tcgaccaaaa
     4501 gtcattccta aacattcgac caatctggcc tttacaggag aatttgtcga gcagccttat
     4561 cagatgatct ttactgaaca aagtgctgta cgttctggag aaatcgctgc tttccatttt
     4621 gcgggtattc ctatgtcccg tcttgtcaaa acaccgcgtt acgacaaaga tattcctact
     4681 ctagctcgtg ccgcaaaaaa aatgtttgaa taatcaagag gttgtgaaaa agctgccctg
     4741 catcaagtaa taagaacaac caggctaaaa cagcttctta tgtttttgat ttggttggac
     4801 ttattaccgc agatgcaagc ttttgaacac cgtttaccaa gaggttgtga aaaagctgcc
     4861 ctgcatcaag taataagaac acccaagcta aaactgcttc ttatgttttt gacttggttg
     4921 gacttattac cgcagatgca agcttttgaa caccatttac caagaggtta tgaaaaagct
     4981 gccctgcatc aagtaataag agcagccaag ctaaaacagc ttcttatgtt tttgacttgg
     5041 ttagacttat taccgcagat gcaagctttt gaacaccgtt taccaagagg ttatgaaaaa
     5101 ggcgtttagt ttcgagtatg aagaaaaatt ttgtgaaaat ggttcctcac gtttttgcat
     5161 aaatttgact taataccgag aaactgatcc cttctgtcat aacctctttt tatttatgtc
     5221 tgtttctttt tgaaaacaac tattttttca acgtttactc tcttgccaat ccaacatcat
     5281 ctaacggata caactatttc aatgattacc attacactaa aaaatcggaa acacacctct
     5341 ccgaacacaa atacataaga ctatagaatg tttcatttaa gaaaaaaagc gtttcattat
     5401 caaaaaggta agatctcctt taaaatgaaa ttatctgtag tactaataat gcagacaatt
     5461 ttatgaatct gaaaggagca tctccaatga aagcagtcac ttggcaagga aaacagaaaa
     5521 tggaaatcag aaacgtagat gatccaaaaa tattagaacc aacagatgca atcatccgta
     5581 tcacagcaac agccatttgc ggctccgatc tgcatcttta ccatcatggt gaagcagttt
     5641 tggaaaaagg gtatgttgta ggacacgaac caatgggaat cgttgaagaa gtgggatctc
     5701 aagttcaaac attgaaaaaa gggcaacgtg tggttatccc ttttaatatt agttgtggtc
     5761 attgtcattt ctgcctgaat cacatggaaa gccaatgtga tgaatcaaat ccagatcagt
     5821 tatatggcgg gcttttcgga tttggcaagt tgaacggtaa tcattggggt ggtcaagcgg
     5881 aatatctaag agttccttat gcagactcta cttcatttgt tgtaccagat aatgatcttc
     5941 ctgatgaaaa agttttattt ctatcagata ttttgcccac agcttattgg agcgttgaaa
     6001 acgcaggagt aaaaaaaggc gatacagttg tgattctagg ttctggtcca gtcggtctat
     6061 tcgctcaaaa attcgctgtt atggctggag cagagcgcgt aatcgcagta gatccagtac
     6121 agcaccgtct agataaagcg gctaattaca atggggttga aacttatttc ttagaagaca
     6181 cggcacaagc tggaacagaa ttgtatgaac tggctaaagg tggcgcagat gtcattatcg
     6241 attgtgtagg aatggacgga ttagagcctg tcaaagaaaa agcgaaaaat ttagtaagct
     6301 tacaaagcgg cacaatctct ccattacaga tggcatcgca agctgtcaaa aaatttggaa
     6361 cagtccaagt aactggtgtt tatatgactc cagcttcttc ttacccgctg caagaatttt
     6421 ttatgcggga tatcgctgtc aagcatggac aggcaccaat tatccatcta atgccaaaaa
     6481 tttacgcaat gattgcagaa ggactattcg atcctacaca aatcattact cattcgctgc
     6541 cactatcaga agcagcacaa gcatatgaga tctttgacaa aaaagaagat aaaaatataa
     6601 aagttgtttt gaaaccttga attcagtaaa aaatacaggt gattttcttt atgcccaaaa
     6661 tcaaacgaaa tacccatgag atcgaaatag gaaaagaaga agatatcgaa atacgaggac
     6721 gtcgcttccg cttctatttc caaaatcgtt acacattgat ctcactggct gtcgatttat
     6781 taaccgggat tttctatatt tttggaagcc ttgcttcctt aactaaaatc cccgatcgat
     6841 atggcaccta tttttatttg gctggtgcta ttttcttgac gattcgtcct attctcagaa
     6901 tcgtaaggaa catttttatt tacgacgaaa aaaaagcaat gaagagaaca agcaaaaaaa
     6961 aagaggcatg agaatttttc aaatctcatg cctctttttt caccctatcg tatcactttg
     7021 atacagacga gcggtcgtcc cactttcttc cttgaccatt gtcaaaaatg tccactcgta
     7081 tcgttcataa aacgtggtat gatctgtaat taagtaaagt ttttcgtacc caagttgatg
     7141 catttctttt ctgatttccg ctaatatccg cttggctatc ccctgcttac gcttttccgg
     7201 ttcaacaaac agggcacaaa gatttggtgt cagatcaggg cggttatgga agtcgttttc
     7261 aatgacgccc gctcctccga cgatggtttc tttttcatct aagaccacat accattgagg
     7321 aatactttcc ttattagcga ttccagtacg aatactttcc tcatacacaa cagcaggaac
     7381 tccccatttt gatgaaaacc aattcgcgct ttgttttact aattctgggt gttctcttaa
     7441 tttgatccag ttatatgtaa ccaatgttta aacctccgac taaaataaaa cgtttacaaa
     7501 aattatacaa gtctttatga aaattagcaa tgacaacaat agtgatgtaa aaaaaaaacg
     7561 gaaaacaatc acttgttctc cgttttttga ttaatcaagc atctaaagct tcttttcttc
     7621 tttcttggat cgtagctacc ttgacgaacg gtagatagat caaaatagaa agaaccaaat
     7681 tgacagcggc tagtacacca cctgcaatac tttttgttgc caatacaccg ccaataattg
     7741 gtggagttac ccatggaggc ataacggtag ctgctggcac taaacctgta gaagtcgcaa
     7801 agtaagcaac actaactaag accattggtg tcaaaataaa tggaatgaac atgatcgggt
     7861 tcaacacgat aggtaaccca aacatcgttg gttcattaat attgaagaca cctggcgcaa
     7921 tcgacaagtt tgttacaacc atatatggtt tgtttttacg tcctactaaa taaatagcta
     7981 acagtaaacc taaagttgca cctgttcctc ctaagttgac aaagctgtca aagaaaggtt
     8041 tgttcacgat aaacggtgcg ctatgcccag ctgcgattgc attaacgttt gcttcaatgg
     8101 ctggcgcatt gattgtttgc atcaaaggat cgaccatatt cgctccgtgt aaaccaaaga
     8161 accataagaa tggtgtgata aatgcaagca gtaaggcaga tggataagag tttgcaagtc
     8221 ccataaatgg ttcttggacc actgtataga aagaacctac gatatcatca acaccgaatg
     8281 cagcaaaaat tgcagcaact aaagcaaacg cagagatagt gatcattgct ggtagtaatg
     8341 aagcaaatgc ttttgcaact gccggtggca caccatcagg cattttgatg atcaattttt
     8401 catttccgct taaacgtaca aagatttctg ttgaaataat cccaacaata atagcaataa
     8461 acaaaccgtt tgagctcata cctaatgctc cgcctaaagc gaagaaagag cctaaagaaa
     8521 tcacacctgc ggaaacaccg tcttttcggt agccgttagc taaatgataa gcaagcaaga
     8581 aagcaatcaa gacagaaaga atggcaaatg taccgttcca agcagcagcc ccgaatcctt
     8641 tccatgattc accaccaaaa attgagttca tcaattcttg gaacccggga atcggtaagt
     8701 tattgatcat tactgctaat gctcctaaga tcattaacgg catactcacc ataaatgagt
     8761 cccgaatcgc aactaaatgc cgttgtgcac caatttttga tgctacaggt ataaaatgtt
     8821 tctccataaa tgcaacaaat ttatccataa atcttccctc ttttctttac tgtagattac
     8881 gcgttcaatc gacgatacag atcaatgatc tcttttgcta aatctgtaaa agctatagat
     8941 gtcatcagat gatcttgact gtggaccgtc aaaagcgtga cttcaacgtg atttccttgt
     9001 gcttcttgtg tcagcatctc tgtttgagag tgatgtgctt ggactaaaga ttcctctgca
     9061 tctttgattt tttcatctgc taaagtgaaa tcaccttttt tcgcagcagc aatcgcttcc
     9121 attgcatcgc tttttgcatt tccgccaaac atgatcagac ccatgatggc ttctagattt
     9181 ttttgatctt ccatttattg tatcctccga taatttttat tatttgttta ttagtttttc
     9241 tgcttggtcg agtacttttt caccattcat catgccatag tcagccatat tgattacatc
     9301 taaaggaatg cctttaggtg ctagcttttc agcaaattga ttttgcataa agcgtacttg
     9361 cggtcctaaa agtaaaacgt ctacattttt agattctagt tgattatccg catctgaagc
     9421 agatacagca aagatgtctg cttccattcc ttttgcttct gctgcctttt gcatttttgt
     9481 gactaggaga cttgtactca ttccagctga acatacaagc atgattgttt tcttttccat
     9541 tttaaacacg ttcctttcta tacttacact tgtatataag caagtagcgt gccaacttta
     9601 aaagcgcttt aaaaagttga tatcatcaca tttaaggtct ataccaagtt gcatacacac
     9661 taaaaaagaa agcgcacact aaacacacaa attaattttt attacctttt ttcttttaac
     9721 gtgcacaaaa aaagttgtga cacaaaactt gtcacaactt ttttcaaata aacggtattc
     9781 aaaagcttgc atctgcggta ataagtccaa ccaagttaaa aacataagat gttgttttta
     9841 ctttgctatt cttattactt gatgcaggac agctttttca caacctctca ataaacggtg
     9901 ttcaatcagc tgaccctggg tattagctca aaacgctgga ttcacaacct cttttatttc
     9961 aaataaccag taaatacaat gaacatctac aaaaaacttc tatttattta tagatttcgt
    10021 caggcaaatc caattctctc ttatcaatca aagtctgata ccacgaagca gattttttca
    10081 atgttctgct tcgttcatcg ttcaattcga ttcgaactaa tccatatcga ttcttaaatg
    10141 cattcattgg tgacacacag tcagtgaatg cccataacat atagccttcg caatttgcgc
    10201 cttcttctgt tgctttgatc aagtaatgca aatgctgtcc gataaattcg atacggtaat
    10261 catcttgcac gattcctttc tcatccatat actgttcttc atattctctt cccataccgt
    10321 tttctgttat cagccaaggg atattatgat aattttcttt tagatacatg gctatatcat
    10381 acatgatttt cggatagatt tcccatcccc tggaattatt cattttcttc ccaggtaaat
    10441 caaagacttc ataatatcgt tcaggatgga aaggtgtctc ttcattccat tgataacgag
    10501 gggcgcgaac gcgtttagga taatattgat tgattccaag gaaatctact gtatgatgct
    10561 gaatcgtttc taaatcctct gttgcaggat cgaaataaat cgattgtttt tgacacaact
    10621 ccaggaactc ttctgtgtag tatcctttta ccatcggatc aaaaaatact cgattataaa
    10681 acaaatcata catataagca gctttttggt cttctggaga attggatcga gcatagacca
    10741 tttcaggatt taaaatacag ccaatccttc caccataatt tccgctgcgg taaatctcta
    10801 ctgctttagc cgttgctaaa actttatgat aattccacat catccacttt tttgtgtttt
    10861 gttcatgcgg ccagcgaaca gcatccaaat agcaacgcgt ttggggaacg attggttcgt
    10921 tgaatgtaaa ccagtttttt accctatcac cgtaacgatc aaaggcaatt tgagcatact
    10981 tagcataaaa atcaactact tttcttgaag accagccatc atatttttcc aaaagaaaag
    11041 ctgggacttc ataatgttcc aaacaaatca tcggttctac gtctgcttcg atcaaagagt
    11101 cgatcatttc acttatatgc tgagcatatt cttcatctac tatacagttc tcataatcag
    11161 taaaaaaacg agcccaattg atagaagtcc gataatgtgt cagatggatg gatttcatca
    11221 gatccacatc ctgctggtat tgttccataa aattagttgc tacggctggg ccatacccat
    11281 tatgccaaac aaaatgttca tttttatacc agctatctat aaacgaatcc tgtccttctt
    11341 tttttccttt ccaaccttcc gtttgccaag cagaagatgc agcaccaaga ataaaatttt
    11401 ttggaatagt aattttcatg atttcctcct gttttttaga tcccatcatt ttccacacga
    11461 tttgctactt ttacaaatgg cagatagatc aaaatagaaa caataataca aacaagttgc
    11521 gtaataactg caccgatatt tcctgctgtt gccagataag cattgacgat cggcggcatt
    11581 ggccaaggga ccattacaac tgctttcgcc gcaaatccta aagcggttgc aaaataacca
    11641 atcgttccag tgataagagg cgttaagata aacggaatag ctaaaattgg attcagcatg
    11701 atcggcatac caaaaataac tggttcattg atgttgaaga tcccaggagc aagggataac
    11761 ttggtgattt gtttcatatc ttcccgtttt ccaactaaca atactgcaat cagtaaaccg
    11821 atcgtgactc cagacccgcc catactcata tacatatccc aaaatggcat agtaataatg
    11881 ttcggtactt cttttccagc ttcaaaagct tccgtattta cagcaattgc cgctaaaagc
    11941 aacggttccc gtatcggctt caccatttga tttccatgga taccaatcac ccaaaagact
    12001 tgcgcaataa acatcaatag caaaataccc ggtaaccctt gtacgacacc ttctaatggg
    12061 cgttgtacga cattgtaaat gatatcataa aggtacattc ctgtaagttc tttgatgata
    12121 aatcccgcag ccgcgatacc cgatacagtc agaatcgtcg ggaataaagc agaaaaacta
    12181 gcagaaacat tcgttggcac ggtatcaggc attctcagct gtagtttctt ctgtttcctc
    12241 aaccagcaat aaagttcaat agaaaggatg gagaccaaca ttcccaaaaa taaccctttc
    12301 gtatctgtat attgtttagc caatacgttt tctactataa cagtctgatt ttcattcact
    12361 aattcataaa cagttggatt aacagataaa taagacatca ctgcgatgat accagggaat
    12421 acaccatcca ctttattcag cttggctaat tcgatcccta tcagaaaaac agcatagatg
    12481 gtcaagaaac ttagtgtgac atagctgatg gcagatgcga taggctttaa ttcttctaaa
    12541 aaacgcaaga aacttatctg tgctaagcca ttttccgagt caaagaccat tgctgaaaac
    12601 aatgtgccaa aagcacccgt aataattacc ggaatcaatg cagcaaatgc gttttttatc
    12661 accatgatat accttaaatt attgattctc gttgccacgt tccctaaaac attggctaat
    12721 ttatccataa aactcattcc agatcccctc attcctgctt cttctccttg acgtcatctc
    12781 tttttgtcta ttagtcagcg cttacatttc gatgaacaga aactatttac tcctcttttt
    12841 taccaaatat aaaacaaaaa ttcatctgat gtatttatca taaaatacat cagatgaact
    12901 gtcaattagt ttctttttct cctattattt tctgtaattc tctccgattt attgccatat
    12961 ggacagtcat tgcatcaaac gcagcaagtg cattccgcct ttcgatggcc tgaacgatct
    13021 ctgtatgaat atcgatcgtc tcgattttca gatgctggat atcataattt ttattaaaca
    13081 aagcaattga ttcattaatg attgggataa tatgcagcaa ggctacgttt ccgctagctt
    13141 ctgcaatcat cgtatgaaaa tcgatgtcta attgaacatg ttcttgtgtg ccttctcgaa
    13201 aagaagtttc aatcttttgc gttaattttt tcatttggac gatttgattc ttcgttgcat
    13261 attccgctgc caaacctgcc atcttaggct ccaataaata tctcagttca aataagtctc
    13321 gtatcatccg atcctgatct tcaatcaaag aaaaaccgag tgggtcattg gcaatccctc
    13381 gcttatcact gacaaatgtc cccgctcctt gccgaacttc aaggatattc ctggaagcta
    13441 gagcccgcac agcttctcgc accgtgcttc gccccacctc taaataatcg gacaattcat
    13501 attcattcgg cagtttatct cctacttgca actgcatttc ctttaaatat ctaaggatct
    13561 tgtcagtagt tacttctact agggttttat tttcttccaa accacatacc tccttttcat
    13621 ctgatgtatt ttttcgtaat tattataaca cgtttgaatc atctgatgat tttttgtata
    13681 caaaattgat taatccgttc atagacatac aaacgaagaa gatatttacc ataaaaaaga
    13741 ctaggataaa
//
LOCUS       DACCVZ010000068        13649 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.071, whole genome shotgun sequence.
ACCESSION   DACCVZ010000068 DACCVZ010000000
VERSION     DACCVZ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13649
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.071"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            25..267
                     /gene="yaaA"
                     /locus_tag="IVW63_002104"
     CDS             25..267
                     /gene="yaaA"
                     /locus_tag="IVW63_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAP7860368.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            254..1378
                     /gene="recF"
                     /locus_tag="IVW63_002105"
     CDS             254..1378
                     /gene="recF"
                     /locus_tag="IVW63_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAP7860369.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            1375..3321
                     /gene="gyrB"
                     /locus_tag="IVW63_002106"
     CDS             1375..3321
                     /gene="gyrB"
                     /locus_tag="IVW63_002106"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAP7860370.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            3341..5812
                     /gene="gyrA"
                     /locus_tag="IVW63_002107"
     CDS             3341..5812
                     /gene="gyrA"
                     /locus_tag="IVW63_002107"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAP7860371.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            6048..6347
                     /locus_tag="IVW63_002108"
     CDS             6048..6347
                     /locus_tag="IVW63_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAP7860372.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            6397..6909
                     /gene="ssb"
                     /locus_tag="IVW63_002109"
     CDS             6397..6909
                     /gene="ssb"
                     /locus_tag="IVW63_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP7860373.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            6935..7171
                     /gene="rpsR"
                     /locus_tag="IVW63_002110"
     CDS             6935..7171
                     /gene="rpsR"
                     /locus_tag="IVW63_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAP7860374.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            7314..9287
                     /locus_tag="IVW63_002111"
     CDS             7314..9287
                     /locus_tag="IVW63_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HAP7860375.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            9293..9745
                     /gene="rplI"
                     /locus_tag="IVW63_002112"
     CDS             9293..9745
                     /gene="rplI"
                     /locus_tag="IVW63_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAP7860376.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            10019..11386
                     /gene="dnaB"
                     /locus_tag="IVW63_002113"
     CDS             10019..11386
                     /gene="dnaB"
                     /locus_tag="IVW63_002113"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAP7860377.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            12166..13458
                     /locus_tag="IVW63_002114"
     CDS             12166..13458
                     /locus_tag="IVW63_002114"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAP7860378.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT         4542 a         2471 c         3009 g         3627 t
ORIGIN      
        1 aataatgaaa atgagggatg ggcattgaaa caacaagtca ttctaaatac ggaattcatg
       61 acgttgggcc aaatgttgaa agaagtcaca gttatcggta gtggcggaca agcaaaatgg
      121 tatttggcag aaaacactgt gttagtcgat ggcgaaccag aaaatcgtcg tggacgcaaa
      181 ctttatcccg gcatgatggt tgaagttcca gaagtaggaa ctttttttat ggtaaaaaaa
      241 ggaaacgacg ataatgaggc tgaataagct gtatttaaaa aattatcgaa attacgaaga
      301 gctgaacatc gaattttcca agaacctcgt catcttttta ggagaaaatg cgcaaggaaa
      361 aacgaatctt ttggaaagta tctacgtatt agctatgacg cgaagtcatc ggacaagtag
      421 tgagcaggaa ttgattggct ggactgacga tcaggcgatg attcaaggag agatcacaaa
      481 aggttcatcc actcttccat tagaaatctt attatctaaa aaaggccgaa aaaccaagat
      541 caaccatatc gaacaaaaaa agttaagtac ttacgtggga caaatgaatg tcattttatt
      601 tgcaccagaa gatctttctt tagtaaaagg cagcccgcag atcaggcgga agtttttaga
      661 tatggaatta ggccagatca atccaatcta tctttatgat cttgtccaat accaagcaat
      721 tttgaaacaa agaaaccagt atttaaagca attgaatgaa aaaaaacaaa ctgatttgct
      781 ttatttggat attttgtccg aacaactagc agcgtttggc agcaaagtat tgaaagcaag
      841 agcacagttc gtcaagcgat tggagttttg ggctaattct ttgcatcagc aaatcaccca
      901 tcaaaaagag cagctggaaa tcgagtatct caccgcagtc gattctttag aaacacatac
      961 gcaagagcaa atccaagaac aatttctcgc acttttgaac caaaataaaa agaaagacct
     1021 ttttcgggga acaacgacag ttggtcctca tcgtgacgat ctttcctttt ttattaatca
     1081 gaaaaatgtg cagacttatg gatcgcaagg acagcaaaga acaactgcac taagtgtcaa
     1141 attagcagaa atcgatttga ttaaagaaga gacgggggaa tatccaatcc ttttgttaga
     1201 tgatgtgatg agcgagctgg atgatagtcg tcaactccat ctgctagaaa caatcgaagg
     1261 aaaagttcaa acgttcttaa caacaacgac acttgaccat gtaaaaaata aaatgactgt
     1321 tgaacctgag attttttatg ttcaacaagg gaaactaaaa ggagaagaaa ctgaatgaca
     1381 gaagaaagaa gtttagtaga acgcgctaaa gagtatgatg ccagtcagat tcaagtactt
     1441 gaaggacttg aagccgttcg taaacgacct ggcatgtata tcggttcgac tagttctgag
     1501 ggtctgcatc accttgtttg ggaaattgtc gataattcga tcgatgaagt attagcaggt
     1561 tttgcaacga aaatccatgt gattattgaa aaagacaaca gtatcaccgt tattgacgac
     1621 ggtcggggga tacctgtaga tatccaggca aaaactggac gtcctgcagt tgaaacggtc
     1681 tttactgttt tacatgctgg aggaaaattc ggcggtggtg ggtacaaagt ttctggtgga
     1741 cttcacggag taggatcttc tgttgttaac gcgctttcta cacagcttga tgtcaaagta
     1801 tacaaagaag gaaatgtgta ctatcaagaa tatcgtcgtg gagctgtagt ggacgactta
     1861 aagattatcg aacaaacgga tcgccatgga acaacggttc actttacgcc agaccctgaa
     1921 atttttacag agacaactga gtttgatttt tcaaaattgg ctacccggat ccgtgaactt
     1981 gctttcttga accgcgggat gcgtatatcg attgaagaca aacgagaaga agaaccagtc
     2041 atcaatgaat accattatga cggcgggatt aaaagttatg tcgaatactt gaatgcaaac
     2101 aaaaccgtga tttttccaga acctgtatat ttggaaggtg aacagcaaga tatcgcagtt
     2161 gaagtctcta tgcaatatac agacggctac cattccaata tcatgagttt tgccaacaat
     2221 atccatacgt atgaaggcgg aacacatgaa tcaggattca agactgcttt aactcgtgtg
     2281 ataaatgatt atgcccgaaa acaaaagctg atgaaagaaa atgacgacaa cttgaccggt
     2341 gaagacgtgc gagaaggatt gacagctgtt atttctatca agcatcctga ccctcaattc
     2401 gaaggacaaa caaaaacaaa attgggcaat tccgaagtac ggacagtcac tgatcggtta
     2461 tttagcgaac atttcatgaa attcttgctg gaaaacccaa gtgtgggccg tcaaattgtt
     2521 gaaaaaggat tactagcttc cagagctcgt ctagcagcga aacgtgcgcg tgaagtaacg
     2581 agacgtaaag gtgctttaga gattagtaat ctgccaggaa aattagcgga ctgctctagc
     2641 aacgatcctg aaaaatgcga attgttcatc gtcgaaggag attcggccgg cggatcagct
     2701 aagcaaggtc gtaatcgaga gtttcaagcc atcttgccta ttcgtgggaa aatcttgaat
     2761 gttgaaaaag caagcatgga caagatcttg gcaaatgaag agatccggtc tttatttact
     2821 gctatgggta cagggtttgg agaagatttt gatgtatcga aagctcgcta ccacaaatta
     2881 gttatcatga ctgatgccga tgtcgacggc gcgcatatcc gtacattgct gctgactctt
     2941 ttttatcgtt acatgcgtcc tattgttgaa gctggatacg tctatattgc tcagccacct
     3001 ttatacgggg taaaacaagg gaagaatatt acgtatgtac aaccaggaaa aaatgcagaa
     3061 gaagagttga aacaagtcgt tgcttcactt cctgcctcac caaaaccaag cgttcagcgt
     3121 tataaaggac ttggagaaat ggatgatcat caactatggg aaacaactat ggacccaagc
     3181 aatcggatga tggcccgcgt cagtgtggac gatgctattg cagcagatca gatatttgaa
     3241 atgttgatgg gggatcgagt agaaccccgt cgtgcattca tcgaggaaaa tgcacactat
     3301 gtgaagaact tagatattta atcatgaagg aggaaaaaga atgagtgaag aaatcagaga
     3361 aaacatccat gatgtcaatc taaccagcga aatgaaagac tccttcatcg attatgcgat
     3421 gagtgttatt gtcgcacgtg cacttcctga tgtcagagat ggtctgaaac ccgttcatcg
     3481 ccgtatttta tacggcatga acgaattagg tgtaacaccg gataaagccc ataaaaaatc
     3541 tgccagaatc gtcggagatg tcatgggtaa ataccatcct catggagact atgcgatcta
     3601 tgagtcaatg gtacggatgg cacagccatt cagctaccgt tatatgctag tggatggtca
     3661 tggaaacttt ggttctgttg acggtgacgg tgccgccgct atgcgttata ccgaagcacg
     3721 gatgagcaaa atcgctacag aaatgctgcg tgatatcaat aagaacactg ttgatttcca
     3781 aagcaactat gatgatacag aaaaagaacc agttgtacta cctgctcgct tcccgaatct
     3841 tttagtgaac ggaacaacgg ggatcgccgt aggtatggcc acgaatatcc cacctcataa
     3901 cttgtctgag gtagtagcgg ctatcgattt gctgatggat aatcctgatg tgacgaccaa
     3961 tgaattgatg gaagtattac ctggaccaga ttttccaaca ggtggtttgg ttatgggaaa
     4021 atcaggaatc cgaagagcgt atgaaacagg taagggttct attaccgtac gtgcaaaagt
     4081 tgagattact gagatgccaa atggtaaaga acggatcatc gtgacagaat tgccttatat
     4141 ggtcaataaa gcaaaattga tcgaacggat ttctgaactg cacagagaca agcgtatcga
     4201 agggatcaca gatttgcggg acgaatcttc ccgtgaaggt atgcggatcg tcattgacat
     4261 ccgtcgtgac gccagcgcat ctgttatctt gaataactta tataaattga catccttgca
     4321 aaattcattt ggattcaata tgttggcgat cgaaaaaggt gtgccgaaag ttttgagctt
     4381 gaaacaaatt cttgaaaact atatcgaaca tcagcgcgaa gtcatcacaa gacggacagt
     4441 ctttgaaaaa gaaaaagcag aagcaagggc acacatttta gaaggtttgc gtattgcttt
     4501 ggatcatatc gatgaaatca ttgcgattat ccgcgggtct aaatcagatg acgaagcaaa
     4561 agcgacgatg atcgaacggt tcgatttatc cgatcgccag tctcaagcta ttttagatat
     4621 gcgtttacgc cgattgaccg gtttggaacg ggaaaaaatc gaaaatgaat accaagaact
     4681 cttaaaactg attgaagatt taactgacat tctggcaaga ccagaacgtg ttacagaaat
     4741 catcaagaat gaattagcag acttgaatca acgatttggt gataaacgac gcacagaatt
     4801 actagtcggt gaggtcttaa gtctggaaga tgaagattta atcgaagaag aagaaatcgt
     4861 tattacattg acaaacaatg gttacatcaa acgtttggca aataatgaat tcagagctca
     4921 acgaaggggt ggacgtggtg tccaaggaat gggtatccac aatgacgact tcgtcaaaaa
     4981 tctggtttct tgttctaccc atgatacatt gttattcttt acgaataacg gaaaagtgta
     5041 tcgggcaaaa ggatacgaaa ttccagaata cgggcgcaca gccaaaggaa taccaattat
     5101 caatttacta ggtatcgatt cgagtgaaag catccaggca atcattgcgg tgacgggaga
     5161 agcagaagaa ggccactatc tcttctttac gacgcgtcaa ggtacagtaa aacgtacttc
     5221 tgtcactgct tttgctaaca tccgaagtaa tggtctgatc gcaattggtt tgaaagaaga
     5281 cgatgagctc gtcaatgtgc tactgacaga tggtcaatct aatatcatta ttggaacaca
     5341 taacggctac tctgtcactt tcaaagaaga agcagtccgc gatatgggac gtacagcttc
     5401 cggggttaga ggaatacgcc tgcgtgagga agattatgtc gttggggcag ccttaatgaa
     5461 ggaagatcaa gaagtattag tgatcacaga aaaaggttac ggaaaacgga caaaagtatc
     5521 ggaatatcca gtgaaaggcc gcggaggtaa agggatcaaa acggcgaaca tcactgaaaa
     5581 aaatggtcca ctagctggat tgaccactgt ttctggagat gaagacatca tgctgattac
     5641 agataaaggt gtcattatcc gtttcaacgt atcgactgtt tctcaaactg gacgttcaac
     5701 attaggcgta cgtttgatga agatggaagc tgatacgaaa gttgtcacga tggcagcagt
     5761 cgaaccagaa gctgcagaac aaacagttga agaacaagga tcagaagaat agccatcaag
     5821 actaattgtg taagctagca agaatgaccg attaaaaaat ctggttattc ctgctggctt
     5881 ttttgattag ttgaatttct cttaaaatat tcgaaactgt tcattctgta ttgcttttga
     5941 ccaaaataga gtgtataatc agagcttgtg agtagtctaa ttaattagat aactctcctt
     6001 gctcttagga acctaagagc cgaaagtcca cagggaggtg aatatcaatg gaaaacacga
     6061 aatatgaaat catgtacatt attcgtccaa acattgatga agaagcaaaa actgctttaa
     6121 tcgaacgttt cgatgcaatc ttgaaagata acggagcaga agttatcgaa tcaaaagatt
     6181 gggaaaaacg ccgtttcgct tatgaaatga acggttaccg tgaaggtatc tatcacatcg
     6241 ttaaagtatc ttctccatca tcagcaaatg ctgtcaatga atttgaccgt cttgctaaaa
     6301 tcaacgacga tatcattcgt cacatgattg ttaaagaaga agcttaattg ttgtttcatg
     6361 tgaaacaata gaaaacgatg agaggagatg actattttga ttaataatgt tgtattagtt
     6421 ggacgtctga cgaaagatcc agatttgcgt tacacagcaa gtggtacggc agtcgcaaca
     6481 tttactttgg ctgtgaatcg taattttaca aaccaaagcg gcaatcgcga ggctgatttt
     6541 atcaactgtg tgatttggcg caaatcagca gaaactttag caaactatgc tcgtaaagga
     6601 acacttttag gtgttactgg acgtatccaa actcgttctt atgataatca gcaaggacaa
     6661 cgtgtatacg tgacagaagt agtagctgac aacttccaat tgctggaaag tcgttctgca
     6721 tctgaaaatc gccaacaaag cggcggattc caaagttctg gtcaatcagc tggcggattt
     6781 ggcggaaaca ataactctaa tcaaacatct caatcatcca acggtatgcc tgatttcgac
     6841 cgtgatactt ctgacccatt cggctcaagt tcaacgatcg acatttcaga cgatgattta
     6901 ccattctaaa cgaatttgat aggagggaaa tagaatggca caacaaagaa gaggcggacg
     6961 taaacgtcgt aaagtagact acattgctgc taaccatatt gaatatatcg attataaaga
     7021 tatcgaatta ctaaaaagat ttatttcaga acgcggtaaa atcttgccac gtcgtgtaac
     7081 tggtacaggc gctaaaaacc aacgtaaaat tactgttgca atcaaacgcg ctcgtatcat
     7141 gggcttgcta cctttcgtta gcgaagacta ataaatccta ggaattgaat gactgatcct
     7201 tttgatcagc tattcaattc ctttttttct gtaaaaataa cctctattcg tttagtcgct
     7261 cgaatgacga aagttatggt aaaatcaaat tagtcatata tgggaggaaa attatggaaa
     7321 ataaaaacaa tcatttatcc ccgaaacctc tcttccttat cctgtttata ttaatcgaag
     7381 tattggtagt cttaatttta ccatttcgtt ttgttagcgc ttcggtcatt ctattgatga
     7441 atttatgggg tgttcgctat tggttgaaaa tgaaacgttg gcttatttta aataaacgtg
     7501 aaaaaatcca gcaggcttcg actgtagctg aaaccaatct agcttatgtc tcagaagtca
     7561 tgcctgtagg agtgattgct tatcagccat caagccaaaa aatcgaatgg ctcaatccat
     7621 tagcattgaa aatcaaagat caaagtggat taacagagga agaattgcta gatacttttt
     7681 ttactgcaaa agaaaaaaag aaaaaccaag tctatctagc agataaaaca tttcagtttg
     7741 atatggatac agtaaagggt gttgtttatt ttaatgatat tacccaaaac cagttgttaa
     7801 aactccatca gacgaacagt cagccggtga ttggtatttt atctattgat aactatgcag
     7861 atgccattga taaattggat gacaaagaga tttcttattt gaactctttc gtcactacac
     7921 tagtttctga ctggatgaat gaataccatg tctttttcaa aagaatcaac gcagaacggt
     7981 ttttcttcgt agcacagatg atcgatctga aaaagatgat ggataaaaaa tttgatttgc
     8041 tggatcgctt tcgagcagaa gctgaaaaac agagctcgcc tatcaccctt agtatgggga
     8101 ttgcttatgg ctcaagaacc ctcgatgaaa tcggtggaga agctcagaat aatttagatg
     8161 ttgctttagt ccgtggaggc gaccaagttg tcgtgaaaga ggtaaaagaa ggagcaaaac
     8221 ctgtttatta tggggggaaa tctgctaaga atgtcaaacg cacgcgtgtt cgttctcgag
     8281 cgatgagtac cgctttgcgt cggatttttg atgaaacagg cgatgtgttt atcatggggc
     8341 acaagtttcc ggatatggat gctttaggct ctgcttttgg tgtcagttgt ctggcacgct
     8401 tcaaccagaa aaaagcttac atcgttatca acgagaacga gatcattcca gatgtagaac
     8461 ggtgtcttga agaaatccat aagcatcctg aattagaaat gcaactaatc tctccagaac
     8521 gtgccataga gctgaaaaaa gaagaggacc tcctcgtgat ggtggattac cataaacctt
     8581 ctctatcgat ctctcagggc ctatatgagc aatttgataa gattgtgatc attgatcacc
     8641 atcgtcgtgg ggaagagttt ccaagtaaac ctctgctgac ttatatcgaa tcttcagctt
     8701 cttcagcttc agagctagtt tctgagctga tccaatacca aagcagcaaa acaaatcgct
     8761 tagatcgttt tgaggccaca ttattgcttg cagggatggt tgtagataca aatagtttca
     8821 atgtccgtac aactgcacga acttttgacg ttgccagcta tttaaggtct tgtggagcag
     8881 acgcatcctt agtacaatat ttattgagct cggatttagc gacatacttg gagatcagca
     8941 atttgattgc tggaagcgac tatgtgactt ctgatattgt tgtggcggca gggacagacg
     9001 aaaaagagta taatagtgtt atagcagcaa aaacagcaga tacattgctt tcgatgatca
     9061 atatcaatgc agctttcgtc attacaaagc ggacagacgg cttgattggg atcagtgcca
     9121 gaagtaccgg cacgatcaac gtccaaatca tcatggaatc cttaggtggc ggaggacact
     9181 tcacaaacgc agctactcaa ctggaaaata cgacagttga ggaaacaaaa cagaagctat
     9241 ttgctgcaat caaagaaaat atgaatcaaa tatatgataa ggagtaatcc aaatgaaagt
     9301 aattttttta caagatgtaa aaggaaaagg taaaaaaggg gacatcaaag aagttccagc
     9361 aggttatgca caaaattatc taatcaaaaa taacttggca aaagaagcaa cgaaaagcag
     9421 tatcagtcag ttagcaggac aaaagaaagc acaagaaaaa cacgaagctg aaatcttgga
     9481 agaagctaaa aagttaaaag aattcttgga aaaagaagat actgtagtcg aattgaaggc
     9541 gaaagcaggg gaagacagcc gtttgtttgg ttcgatccct tcaaaacaaa ttgctgaagg
     9601 gttaaacaaa caatacaaaa tcaaattaga taaacgaaaa atcgaattag aaaatccgat
     9661 ccgttcacta ggctacacaa acgtacctgt taagcttcat catgaggtga cggctacgat
     9721 caaagttcat gtcgtacaag aataacaaat cttgatagcg atgttcagct ggtaagtata
     9781 accagaagga aaaaagacaa accgaaattt atctgagaaa acagctgcag caatgaaagc
     9841 aaaagctgca aatcgatttc agattgattt cggtttcttt tttgggaaca gcaaaatagc
     9901 ataaagaaaa cgagtataat aaaagagaac tattttttta ttacactttc ggtacgaatg
     9961 atgacttttc tctcattttc ttgtaaaatg aagcaattga agacaaggag cgatacgtat
    10021 gaatgaagtg tggcaggatc gaatcccacc gcaaaatatt gaagctgaac aagcggtttt
    10081 aggctctgtt tttcttgacg cagaaacgat cattgatgcc atggagtaca tagagccaaa
    10141 agacttttat cgtcgtggcc atcaaattat ttttgagaca atgatcgagt taaatgatcg
    10201 taatgaagcg attgacgtgg ttactgtcaa agaccggctg gaacaagcca atttgttaga
    10261 agatgccggt ggtttaagtt atctctcaga cttggcatta gcagttccga cagcagcaaa
    10321 tatcgtctac tatgcgaaaa tcgttgaaga aaaatcattg ctgcgtacat tgatccagac
    10381 agcaacagga atcgttacga aaggattcga gcaaggagaa gaagttcaaa caattttaga
    10441 tgatgccgaa cgcagtatct tggaggtttc ggaaaaaaga aatcgaagcg gctttttatc
    10501 tattgctgaa gtactgaact ccacgattga aaatatcgat cgactagctc aaaacaatga
    10561 agaaatcaca ggtctaccaa ctggctatca aggtctggat aaaatgacag caggtttcca
    10621 gcccgaagaa ctaatcattc ttgctgcacg tccagcggta ggtaaaacag cgtttgcatt
    10681 gaatattgct caaaatgtag gaacaaaaac agatcgttct gttgcgatat ttagtttgga
    10741 aatgggggca gaatctcttg taaatcggat gctttgtgca gaaggttcga ttgaggccag
    10801 ccatttacgt acaggtcagc tttcggaaga agaatggtcg aatctgatcg ttgcgatggg
    10861 gagtctttct cgagcaaata tttttatcga tgatacacca gggatcaaaa tctctgaaat
    10921 ccgtgcgaaa tgtcggaaac tagcgcaaga aaaaggcaat ctaggcttga tattgatcga
    10981 ttatttgcag ttgattgaag gtaacggtaa agagaaccgt caacaagaag tatcagatat
    11041 ctctcgccaa ctgaaaaaac tggcgaaaga gctgaaagta cctgtcattg ctctttcaca
    11101 gttatctcgt ggagtagaac agcgacaaga caaacgacca gtgctaagtg atattcgtga
    11161 atccggatca attgaacaag atgcggacat cgtagccttc ttgtatcgag atgattatta
    11221 tgaaagagaa ggcggagatg acgatgatgg aaacgagcca aaaaatgaca acgtcatcga
    11281 agtcatcatc gagaagaacc gaagcggtgc acgaggaaca gttgaactac tgtttatcaa
    11341 agaatacaat aagttttcgt cgctttcgcc aagagaagaa ttttaaagaa gaggttgtga
    11401 gccttgagca atcccgagag ctctcgtaag aagatgcaag gagtaaccgc aggaacgact
    11461 agagtactta atttaaacag atctccaaag ggattgtgac aaaagtcttg tcacagtccc
    11521 tttttccgaa taaacggtgt tcaatcagct gacccttggt attagctcag caaacgtcaa
    11581 aatatgagga actattttga cgtttgtttc tctaatactc aggtcaaaac gctgatctta
    11641 cgacctcttt tccttaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatc
    11701 atcaaacatg agaagcagtt ttttgaaatt gctccttgtg actcagagtt aaacggcagg
    11761 ctcacaacct ctttcttaaa cggtgttcaa aagcttgcat ctgcggtaat acgcccaatc
    11821 aaacgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga tgcaggacag
    11881 ctttttcaca acctctgatt cacggtgttc caaaagtagc ttcttcgaaa aataagtcga
    11941 aatttcacaa aaatttgaga agcaattttc gtacattcct tcttatttct tgaagctgac
    12001 cacttctgtt acaacctctt ttttaataac cattctaaaa agataaagtt cgttttttaa
    12061 gcgtttttat aaaataaaaa taaaaatcat tcgattttat ttgaaatatg tatctattat
    12121 tgatacaatg gttcaggatt aaataatata gaacgaggtg ttcacatgtc atctgtagta
    12181 gtagtaggta cgcaatgggg cgatgaaggg aaaggaaaaa tcacagactt tctcagtgaa
    12241 aatgctgaag tgattgcacg gtaccaaggt ggcgacaatg cagggcacac aattaagttt
    12301 aacggtgtga cttataaact gcatttgatt ccttctggga ttttttataa agacaagatc
    12361 agtgtgatcg gaaacggcgt tgtagtcaat cctaaatcat tggttaaaga attagcttat
    12421 ttacatgaaa aaggtgtaga aacaagtaat ttgcgtattt ctgaccgcgc gcacgtaatc
    12481 ttgccttatc atatcaaatt ggaccaatta caagaagatg ctaagggcga aaataagatt
    12541 ggtacaacga ttaaaggaat cggacctgcc tatatggata aagcagctcg tgtaggtatc
    12601 cgtattgcag acttattaga taaagaaatt tttgaagaac gtcttcgttt gaatctagat
    12661 gacaaaaacc gtcaatttgt aaaaatgttt gattcagaac cacttgattt tgacgatatt
    12721 tttgaagaat attatgaata cggacaacaa atcaaacaat acgtcacaga tacttccgtt
    12781 atcttgaatg atgctttgga tgcaggcaaa cgcgtgttgt ttgaaggcgc acaaggtgta
    12841 atgctggata tcgaccaggg aacttatcct tttgttactt cttctaaccc agtagccggt
    12901 ggggtaacaa tcggaagcgg tgtagggcct tcaaaaatca ataaagttgt cggcgtctgc
    12961 aaagcctata cgtcacgtgt cggtgatgga ccatttccaa ctgaattatt tgatgaaaca
    13021 ggagaacaaa tccgcgaagt aggacgagaa tacggtacga caactggtcg tccgcgtcgt
    13081 gtaggctggt ttgattctgt agttatgcgc cattctaaac gagtttcagg tattaccaac
    13141 ctatctttaa actcgatcga tgtattaagt ggattggaaa cagtaaaaat ttgtacggct
    13201 tatgaattag atggcgaact aatctaccac tatccagcaa gcttgaaaga gttgaaccgc
    13261 tgcaaaccaa tctatgaaga attgccaggc tggtcagaag acattacagg atgcaaaaca
    13321 cttgcagaac tgccagaaaa cgcacgtaac tatgtacgtc gtatctcaga gcttgttggt
    13381 gtacgtatct caacattttc tgtcggacct gatagaacac aaacaaacat cttagaaagc
    13441 gtctgggcgc aaatctaagg ataaaaacga cgactgaatc aggacgttct taccagagcg
    13501 agtcgaagtg tttatctata cgataataat aacttgaaga ggtagtgaaa gagacgttta
    13561 gccttattgc cgataggctg tctcttgaac actgtttatt cagaataagg gactgtgaca
    13621 aaaaccgtgt cacagtccct ttttccgaa
//
LOCUS       DACCVZ010000069        13358 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.072, whole genome shotgun sequence.
ACCESSION   DACCVZ010000069 DACCVZ010000000
VERSION     DACCVZ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.072"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            4..2376
                     /locus_tag="IVW63_002115"
     CDS             4..2376
                     /locus_tag="IVW63_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860379.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="IVW63_002116"
     CDS             2437..3897
                     /locus_tag="IVW63_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAP7860380.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3908..6112
                     /gene="topB"
                     /locus_tag="IVW63_002117"
     CDS             3908..6112
                     /gene="topB"
                     /locus_tag="IVW63_002117"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP7860381.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6352..6945
                     /locus_tag="IVW63_002118"
     CDS             6352..6945
                     /locus_tag="IVW63_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection protein"
                     /protein_id="HAP7860382.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6958..7857
                     /locus_tag="IVW63_002119"
     CDS             6958..7857
                     /locus_tag="IVW63_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAP7860383.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7860..8357
                     /gene="ssb"
                     /locus_tag="IVW63_002120"
     CDS             7860..8357
                     /gene="ssb"
                     /locus_tag="IVW63_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP7860384.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8723..8983
                     /locus_tag="IVW63_002121"
     CDS             8723..8983
                     /locus_tag="IVW63_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860385.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9428..9634
                     /locus_tag="IVW63_002122"
     CDS             9428..9634
                     /locus_tag="IVW63_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAP7860386.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPYTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9634..9885
                     /locus_tag="IVW63_002123"
     CDS             9634..9885
                     /locus_tag="IVW63_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860387.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            9901..10338
                     /locus_tag="IVW63_002124"
     CDS             9901..10338
                     /locus_tag="IVW63_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860388.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGQWFFQALLCLEAGVKPNTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYLENVNKYGACYIMKKEDNENE"
     gene            10331..11038
                     /locus_tag="IVW63_002125"
     CDS             10331..11038
                     /locus_tag="IVW63_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860389.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11418..11597
                     /locus_tag="IVW63_002126"
     CDS             11418..11597
                     /locus_tag="IVW63_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860390.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11922..12185
                     /locus_tag="IVW63_002127"
     CDS             11922..12185
                     /locus_tag="IVW63_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HAP7860391.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12179..12529
                     /locus_tag="IVW63_002128"
     CDS             12179..12529
                     /locus_tag="IVW63_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP7860392.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12553..13167)
                     /locus_tag="IVW63_002129"
     CDS             complement(12553..13167)
                     /locus_tag="IVW63_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7860393.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
BASE COUNT         4937 a         2207 c         2748 g         3466 t
ORIGIN      
        1 aacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ctagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccaaaaa
      121 atgacgaacg gtcaaccaat gaacgacaag aggaatggcc gttcatggtt taaccagcaa
      181 gaacgaatcg aaaataaagt ccaaagtctg agagaagaga tcaagcaaca agaagaatac
      241 gtggaaaagc ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgataa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcgg ctttttcagc cgccacgatc cgaaaatacc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 ggctatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctaga
      661 ccaactgatt ctatgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt cgaattgatc
      781 gatcaactca aaacattgga taaccaatac gccgcagaag caggttatta taaattctat
      841 tttgaggaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaaccaat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaagggt tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctatacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gtcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tttagaaacg ccagagaata agaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtaat tttaaaagga
     2221 aaaagttatg gaaaagagat ccaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga gacagtgtca gaagtggcaa aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgt gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt tttaaaatga ccgagaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagatta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac cctaagcaac aatttaaagc agccactgat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgaaacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     2881 gccgaactaa agccaaaata tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaaag agacagtagg ggcgagttat
     3001 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagataaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     3181 gatacgtggt tagtctctat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagtcgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aaatcattta tgaagaagtc gcaaaagaag aaaaggtcac accagaagct
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaact ggtttccgct
     3541 cacaaagtaa atgcgttttt tggccagcag ctttctgtta acgattcaat agaagccatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagtttgtga acgcgtggat
     3661 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc gcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttgta
     3781 cctgaagtaa aaaaggactg gaacgatcaa ttgaagcatg agatccagca acaagaaatc
     3841 agaaagcaaa aacgtgccat gttgtttcaa caaggcagac aacaagaaag ggagtgaaat
     3901 cgtcatgatg aaaaccgtta ttttagcaga aaagccgtca caagcgaaag cttatgccga
     3961 tagcttctct aaagccactc gaaaagacgg gtattttgaa atccaagatc gattgtttcc
     4021 tggtgaaact gtgatcacgt atggttttgg tcatttagtc gaattagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agaacatttg cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatcgcttg
     4261 gacgatcatt caacaagtag gcgccgatca aggaaaaacc tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagacg caaaagagac
     4381 ctatccaaaa tttgaagaag cacaagcacg tcagatcgcc gattggttaa ttgggatgaa
     4441 cggtagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gcttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttgcaggaaa agattagaaa
     4561 tttcaagaaa gaaccttatt ttgaaggaaa atccgaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggcatg attcgccaag ttgaaaccga
     4741 gaaaaaaagc gcggcaagtc cacgtctttt ttctctatcc agccttcagt ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagacac tttggaagcc atgcaaggct tgtatgaagg
     4861 gaaatatcta agctatccgc gaacggatac cccttacatt acggaagggg aatatgcgta
     4921 tctgttggat cacttagacg aatacaagca ttttttgagg gctgaagaaa tttcgactcc
     4981 tattcataca ccgaatagta ggtacgtgaa caacaagaaa gtccaggaac attacgcaat
     5041 cattcctaca aaaacagtta tgacagaagc gacgtatgaa agtctgacac ctttacaaca
     5101 agcgatttac gagcaagttt taaaaacgac agtggcgatg tttgcggaaa aatataccta
     5161 tgaagaaaca acgatcttga cgcaagtcca gcagcttcag ttaaaggcaa tcggaaaagt
     5221 accgatagat ctaggttgga agaagttatt tggcaaagag agcgacggaa aagagaagga
     5281 agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtag atctacaagt
     5341 ccttgaaaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga tcactgcgat
     5401 gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga aagaagtgga
     5461 aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac aaaaggaata
     5521 tatcaaggta gagaaaaata agcttgtggt gacgaataaa ggggttttgc tttgccaagc
     5581 tgtggaaaaa gagccgctgc ttacgagtgc cgaaatgacc gccaaatggg aaagctactt
     5641 gttaaagatt ggagaacgaa aaggaacaca aaccactttt ctagccaata tccaaaagtt
     5701 tgtctctcac ttattggaag tcgtcccagg acaaatccaa tccattgatt ttggatcgac
     5761 gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt taggaatttg
     5821 tccaaaatgc caggaacaag aagtcttact ctatcaaaag gtggcagctt gtacgtctga
     5881 agcctgtgat tttaaattat ggacaacgat tgccaaaaag aaactcacag cgacacagct
     5941 gaaggagatt attcaaaata gccgaacaag ccaaccagtg aaagggttaa aaggtcagaa
     6001 gggttcgttt gaagcaacga ttgttttaaa agaagacttc actacaggct ttgaattttc
     6061 tgaaaagaaa aaaacgaact tcaagaaaag aacacgacgc acgacaaaat aatggagggt
     6121 taatcttatg cgtaatacaa cacacaaaca acaagaaatc gaaaatcaaa aagccaaaat
     6181 tcgttcagaa caagagaaat tacgtgccag taaaagaaga cttcagcaat taaagaacca
     6241 gcaacggatt caaaaagaaa tcgaattaga tcgatagaca ttaaccttgt tacaaataca
     6301 ctatcatgat atatttaatg tagtgtattt gtaacaaaag gggggaagta aatgcaagag
     6361 aaactgaaag aattgttggc tattcgcgat ggaaatttat ctatgaagga agccagaaaa
     6421 ttaggaatcg cagcaaccac tgtacaaaga ttggtgaatc aaggaaaatt gatcaaagtt
     6481 gatcgtggtt attatgtaga ggatggtcat ggaatagatg atttattttg gcttcagcaa
     6541 cgtttttcca ggggaatctt ctctcatgaa acgactttag atatttacca gctttctacg
     6601 aatatgccga aattcattca cttaactttt ccccatggat ataacgttga tcgttcaatt
     6661 acaaaagagc agcagttaca atttcatttc gtgaagaaag aagtttatga actaggaaaa
     6721 gtagagggaa cttcctttca aggaaatcct attactatgt atgataaaga gcgtacactt
     6781 tgtgatattt ggaatccgag atatgaaatt gaatatgaaa tgaaattaga agcattaaaa
     6841 gagtacatgg aagacccatt gagagatcca agtaaattaa gagattacat gacaaaacta
     6901 catgtagaaa aagaaatgaa ataccacatg caaagcttat attgatggag gaaaaagatg
     6961 acaccgacac aatttgcagc aaaaacaaga aatttagcaa agaggacagg attaaatgca
     7021 cagttagtac aacggcattt tatgatggat cgtttaattg aacaaatttc tgaatctaag
     7081 tataaaaatg atttcatttt gaaaggtggc tttttattag gatcaaaata tggaatcgat
     7141 agaaggacga caattgatat cgacacgaca tttagaaata gcaaattaac tgaagaaaaa
     7201 ttgaagagta tttttaatga tttaactagg aaacccacga aagaaggtat tgttttctct
     7261 attcaaggaa tgaaggaaac aagagaagcc gatttttatc ctggatttca aattaaattg
     7321 gtggctaatt tagagaaagt acgtgtgcca tttaaaatgg acgtgacaac aggagattct
     7381 atttatcctg aagtagatac acactatcac caattaatgt ttgaagataa aaaggtggag
     7441 attccagctt atccaacagc acaaattatt gcagaaaagc taagtgctac gttcagcttt
     7501 ggcacagata attcgagagc aaaagattac tacgacttat ttaccattcc gaaactagaa
     7561 aatatcgata cgaaagagtt atacaaaagt gttcgaaata catttacaaa acgtggggat
     7621 acaaaaccgt tgtcctttta ttatgaaaga gaaatggata agatcatagg aaatgactat
     7681 ttggaaaagc agtgggaaaa atatcgctca gttaacacgt ttgcgaattc catttcattt
     7741 acagatacag tcaacgaaat tgatcaccta atgaaaagtg tgatcaaaat tgaaaatcaa
     7801 gaaagaaaac ggcagtttaa aagatcacaa caaatgaatc aagaaatgga gagataaaga
     7861 tgatcaataa tgtaacttta gtaggacgct taaccaaaga tccagattta cgttataccg
     7921 cgagtggtac tgcagtagcg acttttaccc tagctgtcaa ccgaaatttc acgaatcaaa
     7981 acggcaatcg agaagctgat tttattaact gtgtgatttg gcgcaaacca gcagaaacaa
     8041 tggtgacatt agctaaaaaa ggtagcttga ttggtgtagt tgggcggatt caaacgcgga
     8101 cttatgacaa ccagcaagga caacgtgtgt atgtgacaga agttgtggcc gataatttcc
     8161 aactattaga aagcaaagca gcgacagaaa gccgtgcgca cgctgatcaa tcgtccacca
     8221 gtccaagcac caccactttt gaacaacggg atacagcgac gcctaataac aatggattga
     8281 acgctttaca gaatccattt gggaatccat ttggtggaca atcaatcgat attagcgatg
     8341 atgatctacc gttctaagta gcattttcta ttggttgcat ttgctacggt ttatgttata
     8401 atttagtcaa caaaaagaat tttcaatcta taaccaaaaa ccactagctg gcgggctagt
     8461 ggttttcttt tacgtttcta ttataagaat taacgggtag gcttactgtc tttcttggca
     8521 aatttacaat caagccattt gcagatatag tgcgcggcta cttctgccat gattgcaaaa
     8581 acaaaatcaa aaagaatttt caaacctata acctcctccc cttgccagat taggccgggg
     8641 tagcagacag caagactatt atagcataat tgaaatatcc aaatgattgg atttttgcta
     8701 taattttagc gaggtgattg tgatgaacaa atatgttggt ttgcttgata aaatccgagt
     8761 aataaaaacg caaccgttat tggttcgctt tactttacaa acgattcatg aatcgattaa
     8821 ttgtgtagtt gcagatattg aaattatcga taaattgcta attatggatg atggaaaata
     8881 caatattgcc gtcacaggtc acttcaataa acgaaatcag ctagttattg ctagcatgta
     8941 tgttagaaat cccgatcatt ttacgcgatc gatgggcata taaaaaaaga agagttgcaa
     9001 tcctaatgta ggactgcagc tctttttgtt ttacatagaa acaagaaaaa tgaaaaggcc
     9061 tttttaggaa ggcgcgagcg ccttctcaat tgaaaaacct ctctcactcc aaccgccacc
     9121 gccgttcgag aagaaaggaa gtgaacgcta cgcgttcact aagataaagg gtcttgcata
     9181 gcaagacaaa atagaaaaaa cttcctctca ccaaaaggtt cgctcctgtt cgttatctct
     9241 ttattgattt gtcagaccgt caacaagttg ccttttatca ccaaaaagcg acaaggacaa
     9301 gggtaaatgg cacgctgcac gcccttgtcc ttgtcgcttt tagttgattc attctggcca
     9361 acaaatcaat aaagaaagaa ctaacgaaag gaagtaaaac ctttcctaag aggaggcaga
     9421 atcaatcatg cgaaagaaat ttgattattg gggtgttccc ttcagcgaat tattcccaaa
     9481 ctatcatgca ccatatactg tcgaatgcga ttgtggagaa agagcgaaat gtatcaaaag
     9541 ctattgtttg tatcaatgtc caacatgcgg gaaaaaatat accttgtctt atggcgatta
     9601 tattttgatt gatgagaaag gaaagaaacg ctgatgaaaa cacaacacaa attattgact
     9661 gtaaaagaag tcgttcaaat tttggtggac aaagaagtca tttctgaaaa agtagcagaa
     9721 gctttactta ttccgcggta ctggacgata gaaacccctt tagtagagga tgcaccgact
     9781 atgctatttg aagacctagt gaagattgca ggatatgaac tgcattatca agaaaacatg
     9841 gaaacttatg aaaacgaata ttggttaacc aaattagaga actaaaaagg agaaaaaaat
     9901 atggctcaaa attactatga cgaatttgtc aaattacctt tggataaaat ggcacaaaaa
     9961 atggaggata tgacattcct atacaatgag acacgtgtac caaaaaaaca ttataaggaa
    10021 agattgtcgg tagctgtgga agaaatgatt gaatcgggtg tcgaaatgaa tctcattgcg
    10081 acctactatc gaacgcttga agaactgaaa aagcaaaatg gacaatggtt tttccaagcc
    10141 ttactatgct tggaagcagg cgtcaagcca aacactatca aaccttctga ataccaagct
    10201 ttagaactaa cgtatgggaa atttgtcgaa acgaaaaaag ccaagactgt ttcaagtgaa
    10261 tggttggact acttagaaaa tgtcaacaag tatggcgcat gttacatcat gaaaaaggag
    10321 gacaacgaaa atgaataagg tgatttatca actaacaacg gaagatgtgt cacacttttt
    10381 aacaaacaaa gaacatttga atgaagtaat cagacggatt caaaaagact ttagttgtat
    10441 ggaagaaatg aagtacttta ttcaaagagt cgaagaacaa ttgtatttgg aaagtgaaac
    10501 gagtcaaacg aaggtcacag tcagcaataa ttatttagac gtgtataaac atcgtcctga
    10561 aacggtaaaa aaaggaacgg agcttctacg actagaaaca gaaaaataca tcatgaatgt
    10621 ttacctagaa aggagtgaac tggtcgaaaa ctttgtcagc tgcacgattt gcaggaaaca
    10681 ctattactca gaatcagaat attattcaat ttttgagagc atggaattaa tggaagaaga
    10741 aatggaagag ctaaacagca aaaatgcgac gatagacgat tattatcttg tatttactag
    10801 atttttgacg tgtggaacgg aatctatcgt gttaatggga atggattatg aactcgctgt
    10861 acccgaagca tttttgaggg aatatgtaga agaagtagat aacccaggcg acgactggta
    10921 cacgacttta actgattttt tagataccta cacttacgac gatacagaag aaatccaaaa
    10981 tgaacttgac cgtaaacgaa tgccatatca acgatttgaa aggaaaaaaa ggcaataatc
    11041 atttataccg aaaagtgaga atgtgtgaaa taagaacaaa aaccttgaaa ttaagggaat
    11101 ggttcttatt tcgcaccaat cgctccaacc gcccccgccg cttaggtggt gcgaaataag
    11161 cgggcaaagc ccgataacct aagagaaaga aggagatcca tatgaataaa atcattcctc
    11221 tgttgttcgt actgtgtatt ggcgagatac ttatgcgtca tggtgcagct gtacatttaa
    11281 acttcgtagt attcttagga atactagtat tttgtttgat tttttggcgc tttgtgttag
    11341 cccttgtgag tctactattc aagttgattg cagccatatt tttcataggg ttatttcgat
    11401 gaaaggagag agtactaatg ccaattgcaa taggaaataa acggttaccc gtgacattag
    11461 atgaaaagag acaaaaagaa ttgcagcaac taaagcagaa gtacggaaaa agtgaatcta
    11521 agattatgtg tattgcgtta gatctattga tcgcgcaaga aaaagcagga tttgatatac
    11581 cagcactaaa aaagtgacgt cacttttcat ttgaagaaac aaaagtgata gcacttaatt
    11641 gttcctacta tttagaatat tttctatgtc ctttttattc cattttgtat caataactat
    11701 gaaatcttta aagtatccag atcaattttt ttcttacctg attctaaaga ttttgttttc
    11761 ttaaacatat tatgatttcc tttcgactat tttcatataa atgttaacat agtttatgga
    11821 ttcatggaat gttaatctaa tttaatagaa aaggataatt aagtatatac gttttttctt
    11881 atgtatgtta tactatgtat atacagaaag aggtgtctac tatggaaatg ttacctataa
    11941 aaaaatgggg aaatagtaat ggccttagat tgccaaagta tattatggaa tatcttggaa
    12001 ttcatacaga agacaaagtg aagataatac aagaagaagt aaacggtcag aagcggctaa
    12061 ttatcgaagc ggctaatata gaaaatgaat taacaattga acagttattt gaaaattaca
    12121 ctgatgaaag aaatcatgtg acgattcaaa atttaggtga agcagtaggt aatgaaaaat
    12181 ggtgagaaaa cctagacaag gcgatattct attattgaat acagcacctc gatctggaca
    12241 cgaacagaca ggtaaaagac cttatattgt tttaagtcat gatattattg cggattatag
    12301 taacgttgtt acagttgctc caatttctag tacaactaga aactatccgc tatatgtaaa
    12361 tataaactca gaatatgaaa tgaagacaac aggaaaagta ttattagatc aactaacgac
    12421 aattgattat gaagccagag agtgtatttt tttggaaaaa gcgcatgata gtttagttga
    12481 ggagttattg atgaaagtta gaacagtttt tcaaaaagta agcaaataaa atagaaacag
    12541 cagcatgatc aactattcgt gattgaccat gctgtctttt tttattctat atacggtttg
    12601 tctcgtaaca ttgtagtctt ttgcaatctt agcgatcgca acaccttttt ttagatcctc
    12661 aacgatgttt ttataaacaa gacgacgttg gggatctttt gcattggcac tgtatagctt
    12721 aggacgtcct ttataaacac cgttcgcttt tgcaatctta atgccttgtg cctgacgtcg
    12781 tttagattcg gtacgttctt gttcagcgat catggccaaa atttgaatga tcaaatcttt
    12841 aatgaattta tccaggagag gattgccaat tgcttcggcc atgatcggta gacttgtgat
    12901 gatcagctgc acatttttct tcttcaagta attgactgaa gcgatgatct cgtcgtaatt
    12961 tcttccaagt cgatcaatag cttccacaat aaaaatatct tgatctcgga cgaaatccag
    13021 tgcttcttga aaaacaggtc gatgagtaat cgttgcgcca gattgtttct caatgaaaat
    13081 tctctctgca ccgaattttt tcatttcttc aatctgccgt tgttcatttt gatcgatgga
    13141 tgagacacgt atgtatgcaa ctctcaaaat ttttacctac tttctgcaac tatttaaaaa
    13201 acaccctaat catacacgag aaaaccagat ttttcaatgt cgcggtcgtg tctagttagg
    13261 gtatacctta tatagacaaa aactaatgat ggaggaaata gtatgtgtca cttttctttt
    13321 taaatggcaa tattttttgt aaataaatgt caatcaag
//
LOCUS       DACCVZ010000070        13292 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.073, whole genome shotgun sequence.
ACCESSION   DACCVZ010000070 DACCVZ010000000
VERSION     DACCVZ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.073"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(105..629)
                     /locus_tag="IVW63_002130"
     CDS             complement(105..629)
                     /locus_tag="IVW63_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7860394.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="IVW63_002131"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="IVW63_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAP7860395.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="IVW63_002132"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="IVW63_002132"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAP7860396.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="IVW63_002133"
     CDS             complement(2351..3031)
                     /locus_tag="IVW63_002133"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAP7860397.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="IVW63_002134"
     CDS             3157..4026
                     /locus_tag="IVW63_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7860398.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="IVW63_002135"
     CDS             4052..4567
                     /locus_tag="IVW63_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860399.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5177)
                     /locus_tag="IVW63_002136"
     CDS             complement(4614..5177)
                     /locus_tag="IVW63_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7860400.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="IVW63_002137"
     CDS             complement(5232..5411)
                     /locus_tag="IVW63_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860401.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="IVW63_002138"
     CDS             complement(5488..5997)
                     /locus_tag="IVW63_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860402.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="IVW63_002139"
     CDS             complement(6093..6473)
                     /locus_tag="IVW63_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP7860403.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /locus_tag="IVW63_002140"
     CDS             6803..7552
                     /locus_tag="IVW63_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HAP7860404.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7873..9090)
                     /locus_tag="IVW63_002141"
     CDS             complement(7873..9090)
                     /locus_tag="IVW63_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP7860405.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(9348..10625)
                     /locus_tag="IVW63_002142"
     CDS             complement(9348..10625)
                     /locus_tag="IVW63_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860406.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(10704..11348)
                     /gene="pcp"
                     /locus_tag="IVW63_002143"
     CDS             complement(10704..11348)
                     /gene="pcp"
                     /locus_tag="IVW63_002143"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAP7860407.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(11547..12491)
                     /locus_tag="IVW63_002144"
     CDS             complement(11547..12491)
                     /locus_tag="IVW63_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAP7860408.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(12493..13179)
                     /locus_tag="IVW63_002145"
     CDS             complement(12493..13179)
                     /locus_tag="IVW63_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAP7860409.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT         3776 a         2774 c         2397 g         4345 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct atttcctacg
     7741 attagtcaag taaaaggtgc aagaaaaata gctcgtaaac gaaagcgaca aaatcaaagc
     7801 acaccaaata aagccccgtt cgtaaaaaat tttcgatctg ggcaaagaag tggtatactg
     7861 taagtggttt agttaatggt ccactgagac cgcgtacgca tagtcgtact ctgtatgtgc
     7921 cctaaccata gcgtgcatac atttcagaag cttgttcata caagcaactg tggcaacctt
     7981 atctttctta gggataggtt gcttttttaa tttgtagtaa taatcgacaa tatgattagg
     8041 agctgcgcgt tgctggcgaa tcatatttcg aatggtgaag aaaataattt tccgtgcttt
     8101 gggattacca cgcttattga tgcggtcttg gccagtatac ttacctgaat gataccgtcg
     8161 gatgtcgatt ccgacaaagg cattcaattg tttatgggtt ttaaatcgtg tgatatctcc
     8221 taattcaccg agcaataaag cggctgtgag tgcgccaatc ccagggaacg tttggtacaa
     8281 caaaaagcaa ggagagcctt cggctttttt gatcatttgt gtcgccagtg cttttttttg
     8341 ttcgagtaaa tcttggagaa gttcggcgta atagatcgtt ttttgacagt ggatactgtc
     8401 tttttcaaca gctggatagg cacactgtgc atagtggatg atttgatctg ccttttgctc
     8461 ggcacgattc gcggagattt ttttccgtgt ttcgttgatc agtttatttt ttatttttgt
     8521 ccgagtagat gccaatacaa aatctggatg gggaaaaaga cggatcaatg tcaatgcgta
     8581 aggggtcagc ctgtttgaaa agaactgttc aagctctgga aaagtcaatt gaaggcagtt
     8641 gtgtaaatcc atgcgcagac gagtgatttt cttctcaatt tcttgataaa aacgggctaa
     8701 atcgcgcatc tctaagtaaa aattgctttg tacttctttt ggctgacgtt gatttttaag
     8761 atgagtctgt gcgagccggt gggcatccga tttatctgtt ttccaactgc gtaaggtgct
     8821 ttcttccatc tgttttttcg cctctaacgg gtttaacaaa cagtaagaaa agtgatgatc
     8881 ttgaaagaac ttttcgactg gtctggaata aatccccgtt gcttcaaaaa caatcaatgg
     8941 acgctcaggc aagtgctgga tctcttcgag taatgcatga aatcctcttt gagtgtgttc
     9001 aatctcgtct tcaaataagc aggtgtcgtc tttgtatagg acactgtagc tgtgtcccat
     9061 tgaaacatct aatgcaagaa tgtaaggcat ttgttttcct cctttttaag ttttgaaaga
     9121 actttactgc ttcatttcga ttccaatttc ctatacacgg gctcatggcc ccaacatacg
     9181 taaacctgat tctaaaatga cagtaaagaa gttcggtttt tgatagggac tcgtagtcct
     9241 caaggctttg ttcgaacttt ctttcactct tcactataat ctaaaaatag aaaatagagg
     9301 agaacatcat tcgtcaatga tgttcccctc taatcttagt atgtttttta tagtaattcc
     9361 ttcagatact ttcttgcctc atcattgaaa cgcagtgatt cttctaactt ctgataatat
     9421 tccaacgctt gtttctgagc ttcagtaaaa cgataatgtt ttcctttcca tttgtcgatt
     9481 gtctcttgca catttccaga ttggatatct ttcactacta gttgccattt ttcttttgag
     9541 actgtacggt ctttcttatc agcagattgt atagcttctc gttctttacg caatactttt
     9601 aaaaaaccat ttctgactat ccgaggaatg ctgtcgaaga acccttctgt aaaaccatag
     9661 cgacaatatt gcttccaaat aaatagatag atttttggtt ggatgaatcg ttggtttttc
     9721 gcaaaatatt ccatctgagc agtgacttct ggtgttcgtt gacgttttgt ctttctcaac
     9781 acggaaataa atgtttcaaa ataagcatta ggatgtactg gcacttcttc atatacgatg
     9841 gattgccaat ctttacgtaa aaatgcgcga tagttgatca agaattcttc tacatccttt
     9901 actaattctt ctgcaaagtc gtcaaatagt tcttttttta tctgtcgctt ttttgactgc
     9961 ccattgatgt gttcacttat tttcttgatt tcattttcca atgcttgata atccgctatg
    10021 taaatcggca tttctacttg gcgaaattct gcgagccgct gagctaattt tatatccggt
    10081 aaatatggct gtttcatccg acgattttgg tacaagacaa aacagtattt ttgccatagt
    10141 ccttcaggaa aatcgatatt cttctgctta agccataata attcgtctaa ggccagatca
    10201 acttttgtca ttccctgatg gatcgaagct gccactgtcg gagagacatg caggtgatcg
    10261 gcaaagtggt tgatgcctag ttttaggatc tttccggttt ttggcgattt aacgatgtat
    10321 tgcactttta attctctacc acactcacaa tacaattttt gctggcttcg ttttgttcga
    10381 aaaaacggat tgatcttgaa gtcagaaaac acccaatctg ttgcagctaa ataatgttct
    10441 tccataaaac gagagctgat tagatatcgg cggtgcttat cgactagttc ccgctgtttt
    10501 ttcgttaatt ttgcatagat ctcccaacgt tgactgcttg tgtattgttt agaaattttg
    10561 atgggatagc ttttgctgat ttcttttgga aaccattctt caaagacgga ttgccattct
    10621 tccacggctg tttctttcct ttctaattac aaaaagctgg ctactaacat aacgttagca
    10681 accagccagt gtttcttgct aaattagtga gttgttccgg catttccgga aatatcttct
    10741 ttattttcta ctgctgcttc aactgcataa gtcaaagaag aagcaatgtc ttctaaagac
    10801 atagaaggcg tacccactgg acgatcgatc acttgatcgg gtgagaatgg cacgtggatg
    10861 aacccacctc gaattgccgg gaattgtgtt tcgatcaaat gaagcaaacg atacatgata
    10921 tcattgcaga caaatgttcc tgctgtataa gagatgtacg ctggtagacc atgatcttgt
    10981 acattttttg tcattgcttt gattggcaat gaggtaaagt aagcggctgg accgttttct
    11041 tctaaagccg tatcgaatgg ctgatttcct tcattatcag ggattcttgc ttctgctaga
    11101 ttgattgcga cacgttcgaa cgagactgct gaccgcccac ctgcttgtcc gacacagatc
    11161 acgacatctg gttggtgctg ttggatggct tctttgacta cttgactgct tttttcgaat
    11221 acggtcggta cttccacttt gatgatttca gcaccgctga tttcatctgg catttttttt
    11281 actgcttcat aggctggatt cactttgtcc ccaccaaatg gatcaaaacc tgttactagt
    11341 actttcatct gttgttcctc cgtccgattg atttaacata tggttatctt ttatcatacc
    11401 attttccttg aacagcgtaa ataaaggaaa caatagttta aataacataa cagatcaaac
    11461 ttaatatatt cttataaaaa aatagtgttc cactacaatg ttagaagagg ttgcgacaat
    11521 tattctgtca caacccctct cttctattat ttaaatagaa tcatataagc aatttggaaa
    11581 actagcataa ataacgcaat aaacaactgg tttttgatca ctccgtattt gtctttcatc
    11641 tccagcatcg ctacaggcac gatattgaag ttagcagcca tcggtgtcag cagggtccca
    11701 caaaaaccgc aagtcaatgc aaccattcct attaacgctg gattcgctcc atgactaaat
    11761 acgaatggtg caccgatccc aaccgtcatc acggtgatgg ccgcaaatgc attccccatg
    11821 attaccgtaa atatcaccat gccaagagcg taaatgatga tgccgatgtt cacatttcct
    11881 tctggaacga tcgtacctac tgcattggaa atcactgtcc caactccagc gcttgtaaat
    11941 accgcaccta gagaagctaa aagcattggc aacatgctta acggccctac tgtgcccagc
    12001 atatctgctg catcatctaa aaatgtactt ggtcgattat ctcgagaaaa gaacatcaag
    12061 attagcatgg ctgcaaaaac accgacgccc acgccgacta aagcacctaa attggtaaat
    12121 agagcaaaca agatcgcaaa gacaccgata ctcaaagctg gaataaaaat tttcattcct
    12181 agtttgtctg acattttttc catatattct tttgatggaa gccggctttc tcctttgctg
    12241 actttcttag caattgctgg tatggtcatc gcaaagatca agccaccgtt cacgattgcc
    12301 ggaagccatc ttcctcctgc aataactacc cctaagaccg tccagaaaaa ggctgaccca
    12361 taacgatgag gattggtttt atctgttaaa tttcttactc cagtgtaaat caatacgagt
    12421 cccatcacga tataaaggat ctccagtaat ttatcgccta ataaaatatc aggatttgta
    12481 aaaaagtcca tcttattgcc cctttcctgg ataatatttc ttcgctaatt tcttttcttt
    12541 aagatagaag tagacacttg ccacaactaa agccgtgata gccactggaa cttccactaa
    12601 agcaagctgt cccaatgtta cgtcatatcc tagatctttc agtgttgatt ggactagcaa
    12661 cgcccctgct cctccgatga atagtacttg gccaaagaac cagcagacat tttccatagc
    12721 tgaagccata ccttttagtt cttcttcatg cttaggatgg acttctaacc cttttgattc
    12781 gatggtcccc aatgccatcg gtaaaatgat tggacgaaca aatccagcaa ctccaccaaa
    12841 actcacgtta aaagccgcaa agatcattcg aaagatccca taaatatcta caatcatacc
    12901 agcagatact ttcttgaatc gcttgatcaa ggaagccgct gattctttca gaccatttct
    12961 ttcaagcgtt cctgttgcca acataatgat gataaaaatc gccatcccgc gattgtttac
    13021 aaaacttgta cctaaaagtt ctaacattcc ttgaatgcca agaccgccag tcaaagctgt
    13081 aacaactaaa gcaaccatta cgatcaatat cgagtctaat ttaaatgcaa acccgagaat
    13141 aacaatcaag acgcctaaaa ggctaagata attttccata tattttcctc cataaaatga
    13201 caatattttt ttaattataa agcaaaacac ataaaaaata tagttgtttt ctcacgaaat
    13261 agacactatt tttaaatatt tttcgttatt tt
//
LOCUS       DACCVZ010000071        13279 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.074, whole genome shotgun sequence.
ACCESSION   DACCVZ010000071 DACCVZ010000000
VERSION     DACCVZ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.074"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(449..1063)
                     /locus_tag="IVW63_002146"
     CDS             complement(449..1063)
                     /locus_tag="IVW63_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP7860410.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1669..2046)
                     /locus_tag="IVW63_002147"
     CDS             complement(1669..2046)
                     /locus_tag="IVW63_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860411.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2346..3227)
                     /gene="galU"
                     /locus_tag="IVW63_002148"
     CDS             complement(2346..3227)
                     /gene="galU"
                     /locus_tag="IVW63_002148"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAP7860412.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(3270..4289)
                     /locus_tag="IVW63_002149"
     CDS             complement(3270..4289)
                     /locus_tag="IVW63_002149"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAP7860413.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(4922..5926)
                     /locus_tag="IVW63_002150"
     CDS             complement(4922..5926)
                     /locus_tag="IVW63_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP7860414.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(5939..6988)
                     /locus_tag="IVW63_002151"
     CDS             complement(5939..6988)
                     /locus_tag="IVW63_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP7860415.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(7005..7826)
                     /locus_tag="IVW63_002152"
     CDS             complement(7005..7826)
                     /locus_tag="IVW63_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP7860416.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(7813..8592)
                     /locus_tag="IVW63_002153"
     CDS             complement(7813..8592)
                     /locus_tag="IVW63_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7860417.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(8609..9079)
                     /locus_tag="IVW63_002154"
     CDS             complement(8609..9079)
                     /locus_tag="IVW63_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7860418.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(9091..9510)
                     /locus_tag="IVW63_002155"
     CDS             complement(9091..9510)
                     /locus_tag="IVW63_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAP7860419.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(9591..12359)
                     /locus_tag="IVW63_002156"
     CDS             complement(9591..12359)
                     /locus_tag="IVW63_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7860420.1"
                     /translation="MLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNTVSH
                     YLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQPKDL
                     FSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLHDLL
                     EDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLDEVH
                     RLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRIPIR
                     IELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGELKNI
                     VKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLMEKQ
                     QPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHELLVY
                     WTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELEQQV
                     SQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIAAHG
                     YATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILVDMG
                     SLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPEWRL
                     LYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNSDPL
                     FSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQRII
                     RNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLIERL
                     IRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSEDTE
                     FLSIEEEF"
     gene            12559..12783
                     /locus_tag="IVW63_002157"
     CDS             12559..12783
                     /locus_tag="IVW63_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860421.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
BASE COUNT         3906 a         2762 c         2154 g         4457 t
ORIGIN      
        1 tccttcaatt tttgtgtatt ttatttctat tagaaaaagg tatcctgttg gacaattttg
       61 ttatatcagg taaacttcat tgcaataatg ataacaaatg tactataatt actttgtaaa
      121 gagttttggg gaagactctt tcatcaacgt gtattaagag acaagaaaga atccatatgg
      181 attctttctt gtctcttttt ccactacttt ttatttttct gacactacat attcttataa
      241 ctcatttctc ataactgtga aacaacttat aaaaataaca aactttaaac aaaacaagct
      301 taaaatcaaa gatgatccat cttaaaataa ctaaaacaaa aaaagtagtc gttgttaatc
      361 ctcattaata atcgttttct ttttttcaaa cgctccattt ttatgtggaa cattattttt
      421 ttaaggaact ttgtcaacat gtggataact attttccact tgtgtcctgg actagctgtt
      481 ttgctgtaaa atacaaaact tgctgcagca aaaagatcgt tgcaagagag gctgttccgc
      541 agatcgctgg atctagattt ggcaaagtca agactgcatc atgtaaattg gcgtggttgt
      601 ccaaaaccaa atcagcaaat tcaaataatc gcaaaccact gctatgttgc gatttgatac
      661 ttcgtgacaa atcaaatcca gtaacaatga ttaatggatg accattttct ttgatccact
      721 gagctagttc gatgattgcc gggtttcttc cttcattcga aagaagaaga aaaatgtctt
      781 ctgatttgac agaaagctga tcaataattg cctgtcctgc accttctagc gtttcataga
      841 cacctccggc tggattttca atcaatatac ttggtacaag atccggggtt tgatcccaaa
      901 attcaaatgc tacaccactt agtgtgcggc tagcatatat ctgcaatcta ccaccttgat
      961 taatttgttt cgcgatccaa gtgccagctt gaagcatcag cggctcttct atccttaatt
     1021 tctcttccaa ttggtgataa tagtcaaaat aacataaact catttatctc tcccgcctag
     1081 ctatacttga catgaataga aacagctgcc taatctaagg aagtacataa aaaaacagta
     1141 gttagacagt aacacatgtg gtctttgctg tttcaaacac aaaaaaggca ttgaacgaat
     1201 acgcccaata ccttgacata gcaaataaaa caacgtgcag accatggaaa atatctacat
     1261 aggggtagaa ttttcaccct agattaggta caataaatta ggtcgatgca ctgcattgac
     1321 tatggcaaaa tgatcggtca gggtgtatgt gtgtgactgg tcattccctg attcttagcg
     1381 ccaactaagg gtcagggagc ctttttttat tcagctgttt ctatctgaat ttattgtaag
     1441 taatctctta tccaagtgca agcaagaaaa tacaaaaaaa cattggtatg atttatatat
     1501 atataaataa cataaaaaaa ggaatggctt atcccgatac aacaagcatt cctttaaaaa
     1561 agattctttt atataagtga aaaaagcttt tttccaccaa ttaaataaat ctctcatctc
     1621 aatagtttat ccattatttt atcttttttt gcgtatacct actaaatatt accgtcttct
     1681 tctcgttctt ctactttgtt cgagagaatc tgtactagaa aaagtagttg tatgtctacc
     1741 ttttctgcct atccgagact ttcttttcat atatgggata taaatgatta gatacagtac
     1801 agcaaaaaat aaagcaaata cgcaagcttc ccaactacct aacgccaatt caaccatcaa
     1861 ggtagcaacc ccaacggatg ctgcatacca gataaaaatc agaaacgttt ctttttttct
     1921 gaccatgcga aacatgataa atagactaat aagcaatagt ggcaacacaa atatccaatt
     1981 gcttccttcc atcagccact tgagtatatc aagcagcgac tgtgcaacag cgactaattt
     2041 tcccatagtg aacacacacc tttttttata attaaaaaat tcgccttttt attctactat
     2101 gaatcttctg gcttggcttt catttctctt atgtaatcat tttcttttat acaacttaaa
     2161 aaaaaattaa accattagca taatattttc tgaatctatt cacgaaagtc tttttctatc
     2221 tttcgttttc cacgactcaa ctgatctaga gtcaaaaaac taaaacgaca gttgcgcaaa
     2281 tgacgcacaa gctgccgctt taataacaaa tagcctttca ttctcagcag gccacttatt
     2341 tccagttaac tttctgttct tagcttttta ctcaactgga taatatatgc acttaatgaa
     2401 gtcccaattt ccgaatgttg aagtccatat tcaatatttg tcttcatata tcctaactta
     2461 tcgcctacgt cgtatctttt tcctttaaac tctctcgcat agaccgcctc tgtctggtta
     2521 agagtctgaa gtgcatccgt tagctgtatc tcgtttcctg ctcctggttc ttgagtttct
     2581 aatatctcaa atattttagg agtcagtaga taacgtccga taatggctaa attacttggt
     2641 gcttttccca tttcaggttt ttctacaaac ccttttactc tgcaacgacc cttttcgcta
     2701 tctgttttag gatcaataat tccgtattta gatgtttcat tttctggtac acgcatgacg
     2761 gcaacagcgg aagcttgtgt ttcttcataa tccatcatca attgttgagt caatgggata
     2821 tcatctttca tcaaatcatc ccccagcatg acgacaaacg gttcatttcc tataaatgct
     2881 tttgcttgaa gcacggcatc ccccagtcct cttggatgag attgacggat gaagtgaaga
     2941 ttgacttgag tcgtttcttc aactaaagcg agtaattctg ttttttcctt ttcccgcaaa
     3001 ttgttttcca attcgatatt tgcatcaaag tgatcttcaa tgggtctttt ttcttttccc
     3061 gttacgatca agatgtcttc gattcccgaa tccaatgctt cttccacaat aaactggatc
     3121 gttggtttat ccacgattgg aagcatttct tttgccatgg cttttgttgc cggcaaaaaa
     3181 cgtgttccta gcccagcggc aggaatgact gcttttttga ccttcacttg ctgttcctcc
     3241 taaacgacga ttaactattg atcatctatt taacgaagag aaaattcatt ctccattttt
     3301 ccgtcacgta acatgatttc ttttgctgct tttttgatat cttctccatt atacaaaaca
     3361 ttatagattg tttgagtaat tggcatctca acacctagct gttgagctag ctctactgct
     3421 gcttttgtcg ttgccacacc ctcaacgacc attcccatgt tttctagaac ttcttccagc
     3481 ttatgtccct gtcctaacaa gttaccggca cgccaattgc gagaatgaac acttgtacaa
     3541 gtaacaatca agtcccccac accactcaaa ccgataaatg tcagaggatt ggcacccatc
     3601 gcgacaccaa gacggctgat ttctgccaat cctcgagtca tgattgctgc ttttgcatca
     3661 tctccgaatc ctaatccatg gatagcgccg gcaccaattg caatgatatt tttcagtgct
     3721 gcaccagttt ctacgccaat cacatcatta tttgtataaa tcctgaaata atcattcatg
     3781 aacagttttt gtacataggc tgctgctttt tgatcaatac ttgcagctgt aattgttgtg
     3841 atatcatgta ctgccacttc ctcagcatgg ctaggaccag ataatacaac aattgcctgt
     3901 cttttttctt ctggaatttc ttcagccaaa acttctgaga ttcgtttatg cgtatcttgt
     3961 tctagtcctt tacttgcatg tataatgatt ggcttagtat tcattttacc aataagttcc
     4021 tgtgcgactg aacgaatcgc ttttgttgga acaacaaata aaatagcatc tgcgttatcc
     4081 actgcttctg ccaattcttt atatccgata atcgattctg ggatcgtcaa atcaggtaaa
     4141 aaatgctgat ttgtatgata cttattgatt tcatcaatct gttcaggtac atttccccaa
     4201 atacggacat catgcccgtt ttctgccaat gtttgtgcta aagcagtgcc ccaagatcca
     4261 ggaccaagaa ctgcgatttt ttgtttcatg gatattcctc caaataaata attgataatt
     4321 tccattatag tatacatttc ttaaagttgg gactaatttc cattgttttt aagtgtttgt
     4381 ttacttcttt tatcgttttt acttgaaata atcaatgata tgttacaata gtctacattt
     4441 tatttttaca ctcgttatgc tttgcttgtt cctaagagga agcagttttg acaatgttac
     4501 taccagcatt actattagga ggttaggaaa cttctcctag tgagtattga tttaaaatac
     4561 ataagagaca gattgaacat ttctaaatct gtcaggtcct gcaacggaca gattgtctct
     4621 gttgacggtt gacataggaa cttttgtttt agtcaacatt ctggatacaa aacgctatgt
     4681 aaactggcgc aactcgttgt acttggactt ttactacgga tccatgcaac aactaaatag
     4741 tactattgca taacaaaaaa tggttggcac ccacatgtcc cattaaacag attataagtt
     4801 gaactgtaga taatgcaaaa aatgtgtttt ataacgtaat tgatgccaat attttaaaaa
     4861 aataaaggga gcagttatcg ctgctctctt tattttttat attcttttta tccagtctat
     4921 cctaataatc aaactgacga tagtagcggc gtatctctaa tggatggcag ttcaactgct
     4981 ccacatgagc atcgatgcgt tgtgtcacta catgcatcaa taagaaagac aaaacacgtc
     5041 cgcgatattt ttcactgata ccttctactg gatagtcttt tgtgtctatc aatgtataat
     5101 tgctgcaaat ttttggcaaa agtttagcca cacgttcaga taacactctc tgttcatctt
     5161 cgcctaaaaa taatgtgact ggggttgttt cttctacgat ctctaacgtc ccgtgaagaa
     5221 actcggcagc atggatagat ttcgatggaa gccagctttg ttcttcccag taacacatgg
     5281 catatgaata aacagctccc cattgattcc ctgctccaat aaaataatgc atactatcac
     5341 gtcgatgttt ttctgcaaat gataagccaa atgcatctgc ttttttctct gcttccacta
     5401 accctgttgg taaataacgt tcgagctgtt catagtattc tgaataagct tcgaattctc
     5461 cattcaaata catcaatcga tctgctgcca taaaaaattt gatttgttct gttccaggag
     5521 ctggataagt gaccacaaaa tcgcatagct gagacaactt actgttcgct ttatcgataa
     5581 atccaatcag tgtcgctcct actttcttga tttgttctac tgctttcact acttcttgag
     5641 ttgtaccggt aacagaggac aaaataacga tagaatcttt tgttaatctt ttgtttccag
     5701 tagtgtaata ttctgcagca tgctgtacaa agacaggcaa gttgcttttc ccattcatat
     5761 aagtgacagc ttgcatcgag gaagcatacg ttccaccgat tcctagataa tagacagcgt
     5821 caaatttttc cgcataaagt ttatcgatga tttcttctac ttgcggacgt aaagctagtg
     5881 cgccttttat tgctttgatt tgttcttctt cattgaattt cagcatgatt tccacctctt
     5941 ataatttact tttcaagact gtatcaaagt cttcaaaaat ctttttgttc aagtcaatac
     6001 ctttagctac tgcggtttta taagcgaata gttgaaacgg aacgacaagc gctaatacag
     6061 acagatattc atcacattct attgctaatc caagtgtttt ctcgtttctt gctttttttg
     6121 tggtaatggt gagagtctct ccaacgtacc gactcatata tctttgcaac ttttgcgaac
     6181 gttccttatt tacactttcc ccttcaataa agaatagcaa atgcgaagca tctgcctcca
     6241 ggtatgggcc gtgcatataa gcttctaact caaatccttg tgacggaacg cggattgttt
     6301 cagtcaattt cgtctctgct tctttagctg ttccccagtt tggaccatat ccaatggtga
     6361 cgaaacgctg tgctaaacga aataaacttt gatatccatc aaaaaattct tccgtttttt
     6421 gaataatcgc tggtaaatgg ttgattattt tgcgcaactg ttgcatgtag tcttgttcta
     6481 tttttttgct gattttattt ttacttattc caattcctat ccctaagagt agtaactgta
     6541 aaacagtcgc agaatagcct tttgtaacga agcctactga ttctaccccg gcacctaaat
     6601 caataatttg tgcagcttct aaagcaagtg gactttgcac gtcatttgtg atagcaacaa
     6661 caggtaaccc ttgtttttgt atcattttta ctgcttcaac agtagaagca cttttcccgc
     6721 tttgtgacac agcaatcaca gtatcgattg aaggagaaag ttttccataa ttgaaaaaat
     6781 aaaaaggttc ttgaatatcg acagtaagat caccataaga ttccaatgct ggcttcgctg
     6841 ctaaacaagc gttataagat gaacccgttg ctaagatcag taaattcact gtttttttca
     6901 tatgttctct tgtcgaaaaa tcattctttt tcaagatcgt acttagtact tccttttctt
     6961 catagatata atcttgcatc gtaaacattt tctctgctcc ttttttaaaa aatccctatc
     7021 cacgaaccaa aaattccaaa gaaagctagt ccgatcaaga tcgttaatgg tttcacttct
     7081 ttcttcaata gataaaacac tatgccaaat gctccaagac ataagatatt tggaacgata
     7141 tcatcaaaaa tactttgaac agtcacagca ttttctcctg aaccgatttt taaaggaata
     7201 ttgatggtga tcatcgtggc agtcattgct ccaacgacca tcagtccaat aatagacgcg
     7261 cctaatgtca aactttccat cataccgttt gcctggatct ttttcaaaaa acccgttcct
     7321 aagcgatatc cccaacctgt tgctagatag cgaaacagaa tgtgcggaat attgaaaatc
     7381 aaaatgaaca agatagggcc taaaatattt ccttgcatgg ctaaagaggt acccacacct
     7441 gtggcaatca atcgcaaagt tccccaaaag aaagaatctc ctaaccctgc aagaggtccc
     7501 atcaaagatg ttttgatact atcgatcgca gtcacatcaa attcaggatc atccttattt
     7561 tcttcctcca ttgcagccgt gattcctaaa atcagtgtaa cgatatgtgg ggtcgtgtta
     7621 aaaaactcta gatgccgttt caaagctgct gccatttctt ctttcgactg atataacttt
     7681 ttcaaaatcg gaatcattgc ataaacataa gccatattca tctgacgttc ataattccaa
     7741 gaaaactcca tttgaaaaga acgccaaaat acgtgattta gctctttttt cgttattttg
     7801 ctgtttttga tctcagaatt cttcatcttc ttctacctcc cctgcagttg tttgaagtgg
     7861 tagttgacgg acattcataa tattgactac cacaactgct aaaatcgcac caaaaatagc
     7921 tactccggtc acaggaatct ctaagtaaga agctatagca aaacctaaga aaaaatatgg
     7981 tgcaacttgt ttgttgatca gcaaacgagc aagcatcgca aaaccaagag ctggaatcaa
     8041 ccctgtagct actgacaacc ccttttgaac gaagtcagga atcatattta atagatttcc
     8101 gatcgtattg cttcccacca tataagaaac cattaccaca acaccaagca tcaaggaaag
     8161 accgataccg gcaagcaagt gcatatgctc gactccttta taatttcctt cttctgcata
     8221 attgtctgct ttatggttca taattggaat caaaagccct aagtaaatat ttttcaatat
     8281 caatgtcaac gtagcaatcg gcaaacctag taaaagcgcg gtttctgtac cggctccagc
     8341 tgtaatagca aaagccgtcc ctaaaatccc accggtcaca acatcaggtg gaatcgaagc
     8401 acctactgag aacgatccga taaatgctaa ctctaaagtt gcgcccataa tgatcccagt
     8461 ttttacatca cctaacacga ttcctgtaaa cagccccgtc acaatcggac gagaaagcaa
     8521 cgatgtccct agtgcatatt ctgattgtgc gacaaatgca acaattccta ataagactgc
     8581 ttgtacaatc attgaggttc ttcctttctt acaaaacttc tcttacatcc acttttttat
     8641 ctgctggtac ttgacggatt tctacttcta tttgtttgtc aattaatcgt ttcaagcgtt
     8701 cctcctcttc tggtaaaata tttaccgctt ttccgatgct gcgagtacca ggttttgcct
     8761 tgatccctcc taagttgatg gttttgattt ctggatacgc ttctgccagc ttatatgcat
     8821 cctcgatcga ttccactacg atgaataact tatatttatc tgtcaccccg cttttcaacg
     8881 cggcaatcga gtcatcaatt gatttgatca ctagtttgac tccttgtggc ttggctaatt
     8941 tgatcgttgt ctttcgtatc tcattcgtag gtacatcatc attagcaatc aaaatacagt
     9001 ctgcgcctat tgtttgtgtc catgaaaaag ctacttgtcc gtgtaataac cgatggtcga
     9061 ctcttgtcaa tacaatcatt tttcttcctc ctaaaattcg tcttcttcta ttttctgatt
     9121 gagccgctcg ttacaaaact ggatcatttt ttttgaatca gttagcacct gctggatcaa
     9181 aacagttgtc tctacttcag cgtccaaccg agatactagc tcaatcaata gtggcaaatt
     9241 caatccggca acgagataga catgatcccg attgatatat tgtaagaatt cgttgttgac
     9301 acttccgcca aaaagatccg tcagaacaat gatttcttta tctttgtacc tcataaaaag
     9361 ctgccttact gtttccgcta aatcaaaatt ctcatcagta tagcaatcga atacagtaat
     9421 agaatgattt ttcccataga tcagctctaa tgaatctaat atccctgaag caaattttcc
     9481 atgggaagct aagataattt ctctatccac tttttcatct cctcttttca cttacacata
     9541 ctaaaaaagc aagttgcatg ccaaaattag tggcaacaac ttgcttatgt tcaaaattct
     9601 tcttctatcg agagaaactc tgtatcttca ctcaaaatat catagatata ggcaatctca
     9661 gaattgggga tcatgacact ataatgctct tcaatgacac taaacgcaga tttaatagca
     9721 gataaccctt ctttttgaca ctgcttccat ttctctaatc cttgataggt ttcgattggc
     9781 atttgtcgga tcaatcgttc aatgagacag ctcacatgga catacaacgc taattttttg
     9841 ggattgctga tgcttcgatt caactgcacc tctaattctc tcataaaatg atcgatttct
     9901 cccatcacct tctctgtatc tagaatagtc acggaatcca gtactttttc caatgaaaaa
     9961 ttacgaatga tgcgctgatt gaatatttcc ttctctgaag cattcatagt agtgtccaac
    10021 cattcagcta gtacagacat cttttccccc gagatgaggt cttctaatga aagatagtcg
    10081 atattggtga tatcaggatc tgtggtgcca atcattccta cgacttcgta tatggaaaat
    10141 aatgggtcac tgtttttctt atcttttaat tgctgatatt catatgggat gattttcaac
    10201 tgacaagccg taggtaagct tttttctagc agttcactta agtggaccgc cgtaccgatt
    10261 ccagtgaagc aagtagtaat gagtgctttg ggtttgtttt cctctggata gagcagtcgc
    10321 cattctggct ggatctgtcg aacagtctct tctgctatct cttctaatga tacatttttt
    10381 tgcaggcatt cccctactgt gattgctaaa ggtgtcgtca cattattcaa aatcaaaagc
    10441 ggtacggata actgtttttt aaaaaactga tggatttctt tcagagatcc catgtctact
    10501 aatatgatca atccatttga aacatcgctg ttttcgcaat aatcaaggat ttctgaagca
    10561 atctgctgtg gtgtgacatc tagtggcata tcaaatgatt caaatagatc ctcttgtaat
    10621 aaacgattta ctacatttgc catactgcta gcagttgcat aaccgtgagc agcaatcatc
    10681 gcttttggca gtcgtttttc ttttgaccat ttcgcttttt ttagatagat cgtcagtaaa
    10741 atccgatcca tacttgtgtc ttcaatatct aatttgatct tacttaattc cagaattcgt
    10801 tggacatagt gataactaga tggataagac tgagaaactt gttgttctaa ttctttgatt
    10861 agttggataa tatcatgttc ttccggtaac catttgatag tgcttcgctg atagagatag
    10921 taactcaagg catagacact gtttccatcg aatttgattt gataggcagt ttccatttgt
    10981 cgaaaggtct ctcggataga ttgtgtccaa taaaccagca gctcgtgttt ttcttgtcta
    11041 ctggtctcaa acagcaaaaa atcaaataat tgaatcactt cttgctttaa ttttccttcg
    11101 caagaatata gcagacagtt atttttcttg aaatcaatta ggatttgctc aaaactttta
    11161 acgattcgct gctgttcggg ctgttgcttc tccattaatt gctctaaggt ctggtcttgc
    11221 gtaatataga ttccttgctg tgctgtattt ttagtaatag gctgcgcaag tagttctttt
    11281 tgcaaatgat ggatcgtgac atggatttca ggctgttcac gctgttcagc atatgctttt
    11341 gctgctgaaa ctttgacgat atttttcagc tctcctatgt ttccggataa tttctgactt
    11401 gttaaaagtg acaaagctgg tccactgact gacaaagggc tccccatttt tctttgttct
    11461 tcgagaaaaa aagagtaaat cagttctagc cgttcattac gactacgctg attaagtgca
    11521 ggtagttcga ttcggatagg tattcttcga atgaaagttg ttaagaaatg actagtaatc
    11581 tcttcagtcg tagcaaaaaa gagacgtgtt ttgatccggc gtgacaaatt aggttctccc
    11641 atacgataaa tcacaccttg atcaagatag gtgaacagtt tttcctgacc ttctggtgtt
    11701 aagcgatgta cctcgtctaa aaacaagatc ccaccatctg ctgcttcaaa agcccctttt
    11761 ttattttctt ctgcaccagt gtacgctccc ttaacatgtc caaacaaatt gctagtcaaa
    11821 agttcaggat tatctgcata ttgtgcacaa ttaaaagtga tgaatggtgc agaatcttct
    11881 agcagatcat gaagcagaca atactgatag accaaattaa ctaaataact tttacctgtg
    11941 ccactttcgc ctgtaatcaa aagtggtaat ccgccatctg gatagtaaag agctgttttg
    12001 atttgttcga tactttcttt caaactggcg tcgtatccga tcataaaaga gaataagtct
    12061 tttggttgcg cgaaaaaagg ctgttcctct ttgagatcat cgatagaaaa ataaaaattc
    12121 gtgcgtaact taaaaaattg tttttcaaaa gcttctttgt ggaaataaat cactggtcga
    12181 gaattgattt tgactagtag ttgctcatca tttaactggt tcaaataatg actgactgtg
    12241 tttcttttta ccccaaaatg atcagctaac ctttgtgctg taaagacctc gttcatatgt
    12301 tctaaatcga aaaaggctgt ctggttctct aagtaacata aaatttcctt cttcaacaac
    12361 ttattcaccc ctcctccatc atagaaaacg gattcatttt gtcaataaaa tctttaataa
    12421 agaattgaaa aatatatctt attatagaca gcagcctact tatcccttat aatttttatt
    12481 ctaaaaaacg tacagttcct tccagttttt atactggaat ttcaacatat gaaagaataa
    12541 ggaggctatg actattcaat gaaatcggat aaatataaaa acaggaaaca tacttcctgg
    12601 aaaacttttc gagaaatcat cggatcttat ctcgctgtag ttgtattttt gcctttgctt
    12661 tatatggcta tgacagaaca aactcgtttt attggcgtag atacgcaata tatagccgaa
    12721 acaggatttt tattcatctt tatcttgatt tttgcgttct ataaatcctt ccatacaaaa
    12781 taagattcac agatttcaac tttcctgtct gtttttagct attacaaatc cttatatgtg
    12841 gtataacaac aatttattgg cataatgagg aaaaacgagt tatgatgctt tcagagagta
    12901 aagaggtact gttgtcacca tcctttttat tgattacgta caccactctt agttttttcc
    12961 cattgattac gaaaacaagg tagaaacatt gatgttccta ccttgttttc tttttttatt
    13021 ttcagatcaa aatctcaagt ggcttttgac ttgatgtcgg gaggttgtct tcgttccatc
    13081 aaacctgata gaatctgcgc caaaccatag ttttctccac tattatttat tcctctaaga
    13141 tagtacccac aataaacgaa taaatatttt tctcattttc atactccttc tttgaaaatc
    13201 aattagattt ctctcaaccc acttttttac aaaaattacg tagcaaaaaa gattgcaaga
    13261 acaaattaaa aaagaagta
//
LOCUS       DACCVZ010000072        13162 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.075, whole genome shotgun sequence.
ACCESSION   DACCVZ010000072 DACCVZ010000000
VERSION     DACCVZ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13162
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.075"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            129..1868
                     /gene="yfcC"
                     /locus_tag="IVW63_002158"
     CDS             129..1868
                     /gene="yfcC"
                     /locus_tag="IVW63_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAP7860422.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2025..3209
                     /gene="iadA"
                     /locus_tag="IVW63_002159"
     CDS             2025..3209
                     /gene="iadA"
                     /locus_tag="IVW63_002159"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAP7860423.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3320..3523
                     /locus_tag="IVW63_002160"
     CDS             3320..3523
                     /locus_tag="IVW63_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAP7860424.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3624..4286)
                     /locus_tag="IVW63_002161"
     CDS             complement(3624..4286)
                     /locus_tag="IVW63_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860425.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4299..5801)
                     /locus_tag="IVW63_002162"
     CDS             complement(4299..5801)
                     /locus_tag="IVW63_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7860426.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6349..8028
                     /locus_tag="IVW63_002163"
     CDS             6349..8028
                     /locus_tag="IVW63_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAP7860427.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8155..8634
                     /locus_tag="IVW63_002164"
     CDS             8155..8634
                     /locus_tag="IVW63_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HAP7860428.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            8853..9533
                     /locus_tag="IVW63_002165"
     CDS             8853..9533
                     /locus_tag="IVW63_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAP7860429.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9541..10872
                     /locus_tag="IVW63_002166"
     CDS             9541..10872
                     /locus_tag="IVW63_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP7860430.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            10887..11849
                     /locus_tag="IVW63_002167"
     CDS             10887..11849
                     /locus_tag="IVW63_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HAP7860431.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            11960..12298
                     /locus_tag="IVW63_002168"
     CDS             11960..12298
                     /locus_tag="IVW63_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAP7860432.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12377..13084
                     /locus_tag="IVW63_002169"
     CDS             12377..13084
                     /locus_tag="IVW63_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAP7860433.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
BASE COUNT         4187 a         2322 c         2885 g         3768 t
ORIGIN      
        1 aacaaaatag aaaaaagtga ttttctaata aattattcat gtggaaatgt catttttact
       61 gtataattca tttgattatc cattttttat tcatcaaaat tactgaaaaa agaaaggaag
      121 aaataaattt gaagaaaaca aattcttcag gaaaaccgaa acgcgacttc actaaattat
      181 cgacacccca tacgtatgtc attatttttg gtgtagtcat ctttgcatgg atactgactt
      241 ttgtcgttcc agcaggaaag ttcagcacgc aagatattga atacaaagat gcaaatggcg
      301 aaacaagtac tcgtactgtt ttacgtcaag attccttccg ttatgcttac gagctggata
      361 agtcgtatgt gtttgatcaa ttagaagaac tgcaagatca tccagcagaa cgtgaaaaac
      421 tggatgttcc ggaaaaagga ttggaaaaag tcattgctga cggagaaaaa aatcttacgc
      481 aggaaaaact agatgaaatc tccttgacag atgatgtgct ttacgatcag tacggcgaaa
      541 atatctatga tacttctaaa aaattgcata aaacagccaa aatatgggga acagatgatt
      601 ttggcggctt tggtttctta aattttgttt ttgaaggact agtatctgga gataagtatg
      661 gatctgctgt agggatcgct gcattgatcc ttgttgttgg aggtgctttt ggtattatta
      721 tgcgtaccgg agcgatcgac gcaggtatct atgcgtttat cagtaaaact aagggactgg
      781 agcgtttagc tttaccgcta ttattctttg ctttttcatt cggtggcgct acattcggga
      841 tggcagaaga ggtaattcca ttctcaatgg tgatggttcc atttgtcatt gcgttaggat
      901 atgactcgat cgtagcagta accgtgactt atgtcgcatc tcaagtcgga aatgcgacct
      961 cttggatgag cccgtttagc gtagcggtgg ctcaagggat tgctggaatc cccgtgttgt
     1021 ctggtgcgac attccgattg attatgtggg tagttgttac tgcattagcc gctggttata
     1081 tgatgatata tgcagaaaaa atccgtaaaa aaccagaaag ttcgttgact tacaaatcag
     1141 atgattattt ccgttctcat atcaaaaaga catctgatga aaataaaaaa ttcatgcttg
     1201 ggcataaatt gatcttatta gagatgttag ttgtccttgt ctggatcgtt tggggcgtga
     1261 ctcaaaaagg ctattacatt ccagaaatcg cttctcaatt ctttgtgatg ggattagttg
     1321 ctggaatcat tgctgttctt ttcaaattag atggaatgaa agtcaatgac atcgcttctt
     1381 ctttccaatc tggtgcagct gatttagctg gtacagcaat cgtagtaggt atggccaaag
     1441 ggattcttct tgtcttggga ggatctgatg catctgttcc ttcagctttg aatacgattt
     1501 tgcatgggat cgggacggcg ttgaccggtg ttccagctgt cattggtgct tgggcgatgt
     1561 acatcttcca aagtttgttc aacttggttg ttacatcaaa ttcaggacaa gcagctttga
     1621 ctatgccaat catggctcca ctggcagatt tagtaggtgt atccagacaa gtagcagttc
     1681 ttgcttatca gcttggttca ggttttatgg acgcttttac acccgtatca gccagcttga
     1741 ttggtgtgct aggtgttgca cggatcgaat gggcaaaatg ggcaagattc caaatcaaga
     1801 tgcaaggatt cctgtttgtt ttaggaacta ttttcatcat gattgccatt gcaataggtc
     1861 tgcagtagta ctggagacct gtaaataaaa aagtaatcca aacagtagat aaggactcca
     1921 agaaccgtca ttttacggta aaatcaaagg agtaaagatc ctatcgtttg gattattttt
     1981 taagatccta tcatcagtta tacttaaaga aagaggaaaa atgtatgaaa atcattcgac
     2041 aaattgaagt gtttgcacca gattacttag gaaaaatgga tgtactgatt gccggtggga
     2101 agattttggc tgtagaagaa cagctagaag gcggctacga aggagtggaa gtagaagaac
     2161 tttcaggtga gggaaaagta ctaaccccgg gtttcattga ctgtcatttc catattttag
     2221 gtggaggagg agaaggcggt tatcaaaatc gaacgccaga agtcacattg agccaattga
     2281 ctacagctgg tgtaacgaca gttgtcggtt gtttgggaac agacggagaa ggtagagata
     2341 tgactgcgtt gatcagcaaa gcgaaaggtc tggaagcaga aggaatctcc acttatgtat
     2401 acgaaggttc gtaccgattg ccggtaaaaa cagtaacaga ttctatcatc aaagactttt
     2461 tgacaattga taaaattatc ggaatcggag aaatcgcagt atccgatcac cgttcttctc
     2521 agccaagttt tgaagagttc gctcgtgcag tagcagatgc tcgtgtagga ggcatgttat
     2581 ccggaaaagc tgggatcatc aatgtccact taggcggagg aaaaagaaag ctagagctat
     2641 tgacacgaat cgtagaagaa acagaaattc cgatcacaca atttttgcct actcatgcaa
     2701 atcgcacacc agaattattt gaagcttgcg tggcatttgc caaacgtggt ggcacgattg
     2761 acttcactgc tagcgaagat cctgattttt gggagaagac agatggtgaa gttcgcttca
     2821 gcaaagcact gaaacgattg atcgaggaag atgtttcttt agataatttc acgatgacct
     2881 cagatggaca aggaagcttg ccttattttg atgaaaacaa tcatttccta gggttaggag
     2941 taggaagtgc caaggcattg ctagtaggga tcaaagaagc tgtgcaaaaa gaaagtatcc
     3001 ctttggaaat cgccttacga gctataacca gtaatccagc acgtatattg aaattggata
     3061 aaaaaggaaa aatcgaaatt ggtgctgatg cagatctgtg tatcttggat aaagaaacgc
     3121 ttgatattga tacagttatc gctaaaggag aaataatggt ccaagaaaaa gaagtcaaag
     3181 tatgggggac tttcgaaaaa agtttttaat caacagctct aactatcttt tttagaaaac
     3241 gagcgttctg tttgtctgta tctgttgttg atgttaccct gaaggtagat caataaacaa
     3301 actaagagga ggaagcacaa tggcagattt aaaaggacgt tctaaagata tgaaagataa
     3361 agtagtcggt gaaggaaaag aagcatacgg caaagcaaca gacgacaaga gcaaagaaac
     3421 agaagggaaa gcacaatcac taggtgctga catcaaagaa aaagctcgaa atttaggcga
     3481 cgaagtcaaa gacaagtttt ctcgaaaaga cgaaaaaaaa taaaaaccac ttattactaa
     3541 ttgaatcaag caaataaaaa atccgaacca tatctgcgag acagatatgg ttcggatttt
     3601 ttatttgatc attatcctgt tttttaaact tcgatttttt gaaatttttt attttttagt
     3661 tcaaagactt catcacagct ttttgctact tcaatctcat gagtcacgat gataatacag
     3721 cgattttgtt catgggcgat ttcttggaaa agtttgacga tatcttgtga agttgtttca
     3781 tctagatttc cagtaggctc atccgctacg attagttgat gttcacagca gatagcacga
     3841 acgatagcga ctcgctgctg ctgacctccc gaaagtttgg tcacctgttt ttttgctaat
     3901 atttcatcaa ttcctacacg agccagtcga tctaaagcaa cttgtcgata attctcttgc
     3961 ttggtcttag tgatttccat tgctgctatg acgttgtcta gagccgataa ataaggaagc
     4021 aagttgtaag cttggaaaat aatcgagaca tcatttttac gataacttct taacccgatt
     4081 ttgttcagtg aacgatcttg atagtatacc tttccttctt ttggtgcatc tagtccagaa
     4141 ataagcgaaa gaaaagtcgt ttttccagaa ccacttgctc ctaaaatagc gtacattttt
     4201 ccagcttcga aattcagttc tacatcttta taaagcgcat cttgcggatc ttgataccaa
     4261 aatcccaatt gttctgtccg taacatcaaa ttcctccttt agtttaatag gatttttctt
     4321 gggtttaatc ttaatatccc tatagaagct aaaaagacag aaaacagact gattccaaat
     4381 gctactccgg ctaatagtcc caattgtgca ggtttgacat tgatttccaa ttcgctgact
     4441 tgatcagaaa cagcaaatgg attattcgtg gttccttgtt gaccatcgcg ttgaccgcct
     4501 tgttcttgtc tgttacctgg catttgtcca ccgccaggag cttgctggtt ttgtgtcgtg
     4561 gtttctgtct gttggtcaag tagctgctgt cccacggcat tcgcgacgac gtttccgcta
     4621 agcgaagcaa ctcctaatgc aagaatcata caaatagcca cttcggtaaa caattggaga
     4681 atgattttac ttctggattc tcctaaagat agcaagacgc ctaactcatg ccgacgctcc
     4741 cgaatggtaa tcataatgat cagagtaagt atgataatac cggctacagc cactagtaaa
     4801 acaacatttt tagaaaaact tgccacgttg tttaaaggtt ccaacattga ctgatacatg
     4861 gaatcatttg attgtaagct aaatgtatct gtgtcgatca gcttctcagc ttctttgaga
     4921 aactcatcca ttttatctgg atcagataga gtgtaaatag cagaatctat cgtgttatcg
     4981 tcagatgtcc catttagttc atttgcaaaa gtgtaagaag tgtaaagtgt attcgacgga
     5041 ttcatgaagt tgaatttcat acccatactg ccgcttgttt cgctggattc ataaattcct
     5101 ttgatcgtca tttcataagt ggtatcttca tcttcagtac tcgtgattgt gaaagtatct
     5161 ccgactgcca ggtcatttgt ttctgctaga gtagaatcaa tgactacatt gtttgtgcct
     5221 ttgtcgctgt catctattcc ttcaccatcc gtgatttttg ctgttccatc agaaaaatta
     5281 ctattttgtg cagttgctga cacaccactg atttgaaagt ctgcttgagt catttgcgga
     5341 ttcccgccca ttcctccagc aggttcaccg cctgcatcag tagtttctga actgtcttca
     5401 cttgaatcag aactagtgat ggcagttatt ccatcttttg ccatagctga ggcggaactt
     5461 tcaaaggaat aactctttac attatctaat tcagctattt tttccgcgtc cgttaaggaa
     5521 actggtgtaa gagaaaaact gcctggatct ggacgttctt cagtggtaga accgcttgaa
     5581 gaagtttgtt cctgtttttt aaatgaagct tctcgattgg cacttaaagt cactgttgct
     5641 ccaacttctt tttgtgcttg attcgctgct tcttctgcag cgcttcgaat cgtgaggcca
     5701 gctagcacaa aaataagaat ggctgtgaac acggcaaaca ataacaatga acgtccccat
     5761 tttacttttg tacttttcca tgcacgtttc ataaaattca tattttgcat ccctcctagt
     5821 agatgcattt gataatagac aacctatctt aaagctagct taaatcttat gctgtttgca
     5881 caccatcaac atgaggttct gtatatataa aaagtcacta tagttattgc aaaaaatgtg
     5941 gtaaaatgaa aaaagtatgt ttcaaaccga cgaagaagaa atgaaagagg aatagcaaaa
     6001 gaaatcctag atgctacaga gggattttta cgtgcatagt tgttctaaca attgctgata
     6061 ctagcgattt agtttatttg ttgtataata atggggaaca gctgaatact tatataagta
     6121 ttctggctat agcgtttcgc aaaagatcca ttttgttaat gaagtatatc caaaataaaa
     6181 tgcccatcca actgtcagaa cgcggatgtg ctggtaattt tcctgctgat tctccataag
     6241 ttgagaaata gtgattttgc atatgcttca ttggaatggc tcatatattt agataaagaa
     6301 gaaaatcgac atctttaaac ttggatgtca taagaagagg tgaagtttgt gagtaccatt
     6361 aaaattatcc cattaggcgg cgttcgtgaa aatggaaaaa acatgtatgt cgcagaagtg
     6421 ggcgaggata tttttatttt agattgtggg ctaaaatatc ctgaaaatga gttgttgggg
     6481 atcgacgtcg taatccctga ttttacgtat ttagaagaaa acattgatcg tgtagctggt
     6541 gtctttttaa cacatggaca tgcagatgcg atcggggcac ttccttactt gttgtcaaaa
     6601 atttctgtac cagtattcgg gacagagttg acgatcgagt tagcaaaatt gaatgtcagt
     6661 cgtaatgaag cagccaaagg atttaaggat ttccatgtgg tagatgagca tacagaaata
     6721 gactttggtg aaacagtagt gagctttttc cgtaccactc atacgatacc agattcagtg
     6781 gggatcaatc tgaaaacaaa agaaggtagt atcgtttata cgggagattt taaatttgac
     6841 caaacggcta tcccaatgta tcaaacagat tatgcacgat tggcggaaat cggcaaagaa
     6901 ggagtcttag ccttactaag tgaatcggca aatgcagaaa atcctcagcc tgtagcttct
     6961 gaagcccaaa tagcagatga agtatttgat acgatcaaat attgggaagg gcgtatcatc
     7021 gtcgcttgtg tagcaagtaa tttgcaacga gtgcaacaag tattggatgc agcagaaaaa
     7081 gcacaacgaa aagttgtctt gactggtcaa gatttcgaac gaattattcg cacagcgatg
     7141 cgtttagaaa aacttcaatt accaagtgaa gatctgcttg ttacgttgaa agacatgaaa
     7201 aactatgatc cagaagaact gatcatttta gaaactggcc gaatgggtga acccatcaag
     7261 tctctgcaaa aaatggcaaa cggtacacac cgtaatgtca agattgaaga aggagatttg
     7321 gtttatatca ctactacgcc aagcatcgcg atggaaacca tcgtggcgaa aacggaagat
     7381 atcatttatc gagctggtgg aacagtgaag ttgatctctg agaatatgcg cgtttctggc
     7441 catgccaatc ctaatgactt gcaattaatg atcaatttga tgaaaccaac atattttgtg
     7501 ccagttcaag gagagtatcg tgaattagct gctcatgcag atttggctca tgcagtaggg
     7561 atgccataca aaaatatcta tattactgga cgcggagacg tgctggaata taagaacaag
     7621 cgtatgagtg ttgcaggaac tacaagtgca gaaaatgtaa tgattgatgg attaggcata
     7681 ggtgatatcg gaaacattgt tttacgtgat cgaaaaatct tgtcagaaga cgggattttc
     7741 gtagcggttg tcactatcag tcggcgagaa aagaaaatca tttcaaaacc tcaaattact
     7801 tcacggggat tcgtttacgt aaaagctagc cgtgatctga tgaaagaaag cagcaatatg
     7861 attgaaacaa tcgttgagaa acatttagaa agcaatgatt ttgagtggag caaattaaag
     7921 caagacatcc gagatcaatt aggccgttac ttatttgaac aaacaaaacg ccgcccagtg
     7981 atcttgccag tcattatgga agctactcaa cgtcgaaata aaaaataaac aaaaagagta
     8041 agatgaacct ctctatagag tgctcgtctt gctctttttt tgcgaaaaac aaataatttt
     8101 tgaatacagc atccctcgct ttataataaa cgatagaata aagggagtga atcaatgatg
     8161 agtcaaacaa aagtcgaacg ttatttagaa gaacaaaaga tcagctatca accacttgat
     8221 tttagtcatg tggtagaaga atctttcaca gaagaactac aaaaaagagg gattgatcca
     8281 gctttgatat gtaaaactct cgtagtgaaa ggaaacaaaa ctggggtgat catcgcattg
     8341 attcctttga acgatcactt agattacaaa aaaacgagac aagtgacgaa agatcgtaaa
     8401 gttggttttc ctggaatgga ttttgtatta atgcatacag gatatcccca cggagcaaac
     8461 acccctattg gaataaaact cgcacatcct gattattgtt ttttagcaga cagttcttta
     8521 aaagaaaaag aagaagtaat tgtgtcaagc ggtgaaatcg ggagaagcct tcggataaaa
     8581 gtagccgatt tagaaaagat cgtccatcct atttacgctg atttaattag ttaagggacg
     8641 agaagagaag ctaagcagag cagagacctc aaacttgaga ttatatctgc ttggtacttg
     8701 gtgcatcctg tattatctgt tacaattgct ttgtacatac tgtactatca atccaatgaa
     8761 aatatattta gcagctatat tttttcattg atgtgcaagt gatgaaatcg tttttaataa
     8821 aaaagataca gagaaaacgc gaggtgtaaa atatgaaaat tacgtatcat ggacattcct
     8881 gtttaacaat tgaaatggaa aatggccaac gcgtgatgat tgacccgttt attacaggaa
     8941 atccattgac agacttaact gcagaagaag taaagacaga ttggttgctg attactcatg
     9001 gtcatagtga ccacatagga gatatgattc ctattgcaaa agaaaatcaa gccacaatta
     9061 tcagtattgt tgagattgct gattatgcga acagcagagg agtagattca ttcggtatga
     9121 atatcggtgg aaaacatgcg tttccattcg gcgtggtaaa attcgtacat gcacagcata
     9181 gttcaagcta tgaagtagac ggtatcgttc agtatatggg cgagcctagc ggaattatta
     9241 ttcaagcaga aggaaaaacg atttatcatg caggggatac tgcttatttc agtgatctag
     9301 gattgcttgc agaagaattc gatattgatg tcgctttctt gccgattggc gataactata
     9361 cgatggggcc agaagatgca gcaaaggctg cgcaaacaat tcgtgccaag aaagtagttc
     9421 caatccatta caatactttc cctgtcattg aacaagatcc cgaatctttt gtagagttac
     9481 tggaagatag tgaaggaaaa ataatgagcg tctcggaaac gctggaagtg taggcagaaa
     9541 atggcgacaa aacatgattt gattttagaa tatattgaaa gtttacctgt tggcaatcga
     9601 atttctgtaa gaagcatcgc aaaagaattg aatgtcagtg aaggaacagc gtaccgtgca
     9661 atcaaagatg cagaaaatgt cggactagtt tcaacaattc aacgagtagg gaccatccgt
     9721 atcgaacgca aattaaaaaa acatattgaa cgtttgacat ttggcgaggt cgtcaggatc
     9781 attgaagggg acgttttagg cggggcggca ggattagaca aggtcttgaa taaattcgtc
     9841 atcggcgcga tgactaaaca tgccatggaa cgctatatta cgccaggatc actaatgatc
     9901 gtcggcaacc gggcggaagt ccaaaaatta gcattggaag atggcgccgc agtattgatc
     9961 acaggaggat tcaatacgac tgctgagatt gcaaagctag ctgatgatct tgaaatgccg
    10021 atcttacgca cctcttatga tacatttaca gtcgcaacca tgatcaaccg agcgttaagc
    10081 gaccaattga tcaaaaaaga tatcatgctt gtcagtgata tctatatgcc agctgaaaag
    10141 actcattatt tgcagcagac agatacgatt tctgattatc agcgtttgtc agaagaaacg
    10201 cagcattcgc gttttccagt cgtcaaccgc catcatcgtt tgatggggat tgttacggca
    10261 aaagatgttt tagggaaatc gccaaaccag atcatcgatc gggtgatgac gaaagaacca
    10321 atcagtgtaa agaaaacaat gagtattgcc tctgttagcc atcaaatgat ctgggatggg
    10381 ctagaagtca tgccggtcgt ttccgatgac ttgacattgg aaggcttgat tacccggcaa
    10441 gatgtaatga aagcgatgca gcttgtccag cgacaaccgc agattgcaga tacgatttcg
    10501 gatcagatat ctggaaatat ccatacgatt gatactgacc gtgaaggaaa tcgtttggaa
    10561 aaccctaagt tcaaattcgt agtagcacca caaatggtca atggcgttgg aaccatttct
    10621 tttggcgtac ttagcgaaat catttctgat gtcgcacaaa aaacaatggt gatgaaccaa
    10681 aaacgaaata tcttgattga acaagtgaac ctacattatt tgcggctgat ccaattggaa
    10741 agcgaattag acattcgtcc acgtgtattg gaaatcggca gacgttccgc taaactggat
    10801 atcgaagtgt ttattgaaaa caccatcgtt tccaaagcaa tcgttgtttg tcaagtaatg
    10861 gaacgttctt agaaagcagg agtgaaatga cagtacagca agaaatagta gatacaataa
    10921 aaaaatacga taaaatcatt atccacaggc atttgcgccc tgatcctgat gcattaggat
    10981 cacaagtagg attagccgaa ctattacggg aaagtttccc agaaaaagaa atacgtcaag
    11041 taggtgaaac gattgaaggg cttcgctttt tagcagaaat gcaagaagtt gaagatgtct
    11101 tctaccaagg agcgctagtc atcgtgactg atacagctaa ttcacccaga atcagtgatc
    11161 aaagatatca gttggcagaa aaactgatca aaatcgacca tcatcccaat gatgaccctt
    11221 atggagatct tgtgtgggta aatacaaaag caagtagctg tagtgagatg attgcagaat
    11281 ttgctttgat gtttcctgaa tctttaaaga tgaacgttaa ggctgcacgg ttactttatg
    11341 caggaatcgt cggagataca gggcgctttt tgtatccctc cacgacgtcc cgtacattag
    11401 agattgcttc gatattgaga aattatccat ttgatgcaag tgctttgaac agagagattg
    11461 aacaaatgcc gatgaaagtc gctaaacttt ccggttatct ttatcaaaat atccaggtgg
    11521 atgaaaatgg tgcaggaaga ataatccttc cgcaagaaat tcttgataaa tatggaatcg
    11581 atgattcaga gacagcttcg atcgtttcac ttcctggagt gattgacgaa gtgctggctt
    11641 gggggatttt tgttcagcag ccttcagggt attaccgcgt acgtttacgt tctaaggggc
    11701 cgatcatcaa tgaattggct aaacgccatc atggaggagg ccatccatta gcaagtggtg
    11761 cgaatgcaaa agatttagca gaagtagagg aaatctataa agagatccaa gatatatgcc
    11821 aatcgtataa gagcagaaaa acagaatgat acttcgttcg aaaacgtgcc ttttgtagta
    11881 aaaatcacaa atgtatcttt tcaagatctt ctttttccgt tacaatagtg ctcactaaag
    11941 attttaaagg agaaagaaga tgacattacc aaattgccca gaatgtggct cagagtacac
    12001 atatgaagat cgaggcttgt tgatttgccc agaatgcggg aacgaatgga acaaagaaga
    12061 acaagaaact gtcatagaag acggattagt ggtattagat gcaaatggaa accgtctgtt
    12121 agagggcgat agcgtgacag tgattaaaga cttgaaagta aaaggtgcgt caggtgccat
    12181 taaacaagga acaaaagtca agaacatccg tttagtagaa ggcgatcata atatcgattg
    12241 caaggtagaa ggatttggac cgatgaaact gaaatcggaa tttgtgaaaa agaattaaag
    12301 aatattcaag gtcttttcac attcttttcc tactactaat gataaaataa agtaaacgaa
    12361 aaggagtgaa acgaaaatgt atggttatgg aatgtatggt tttttagatc cgacatttct
    12421 tttggtcatt cttggattag ttatttccgg aattgcgtca gcgtacgtca atagtacttt
    12481 ccgaaaatac gatcaagtga gaagcaaaaa caatgtgact ggtacacaag cagcacaata
    12541 tatattacaa agtcaacaga taaataatgt cggtgttcaa caaattgccg gagatctcac
    12601 agataactac aattcaggta ataagatgtt gagtttgtct caagcaactg cacagtctac
    12661 ttcagttgct gcgataggtg tagcagctca tgaatgcgga catgcggtac aagatgcttc
    12721 gggttatgtc ccattgaaga ttcgtgcagc acttgttcca gcagctaact ttggttcgat
    12781 gatttcgttc cccttgatta tggtaggtgt attgcttagc tggaactcta cgttaatcaa
    12841 tatcgggatt ttcgcttttt ctttagcatt acttttccaa ttggtgacat taccagtcga
    12901 atttaacgcg tctcggcgag caatccaaat tttgagtgaa ggcggactac tgacggaaga
    12961 agaagtaccg atggcaagac acgtattatt tgcagcagca ctgacttatg ttgcagcagc
    13021 gctttcgaca ttcctgcagc tgttgcgctt gatcttattg ttcggcggca accgaagaga
    13081 ttaaaataaa gaagttgtga aatcagcgct ttgatctgag ctaataccga gagttagctg
    13141 attgaatacc atttatttgg aa
//
LOCUS       DACCVZ010000073        13048 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.076, whole genome shotgun sequence.
ACCESSION   DACCVZ010000073 DACCVZ010000000
VERSION     DACCVZ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.076"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            62..964
                     /locus_tag="IVW63_002170"
     CDS             62..964
                     /locus_tag="IVW63_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP7860434.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNDVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            complement(1004..2884)
                     /locus_tag="IVW63_002171"
     CDS             complement(1004..2884)
                     /locus_tag="IVW63_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7860435.1"
                     /translation="MGKYQELAENIVKNIGGKENIRSLTHCVTRLRFKLKEENKAKDD
                     VLKKMEGIVTIMKSGGQYQVVIGNHVPDVYAEVLTVAGISDEAEEEVSSSSNLFNRLI
                     DILSGCFQPFLGALAAAGMVKGLNALFLFLKFYTEGSGTYIMLNGIGDAIFYFMPVIL
                     GYTAAKKFHLNPMVGLVIGAALCYPTVQGAALQSGFPDGSPAPYSLLGLPAYETFLGI
                     PWVGSSYTSSVVPVIFIIAFAGQVQKIAKKWIPAVVQTFLVSFSVLLIALPAGFLIIG
                     PIVSILTDLLSTGFQALMDFSPAVYGAVLGFLWQVLVIFGLHWSIIPLAIMQLAQNGW
                     SQMLVGVYGASFAQTAVVLAMYFKFKDQKMKALCMPAVISGIFGVTEPAIYGITLPKK
                     KPFIYSMIGGAVSGIYLMASGTISYIMGGLGIFGVVNYITETDASGMFQAFIGIAIAS
                     VIGFSLTFFFWKDEAGETDAIQKKSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGRGI
                     LIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESLVQ
                     QGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALITA
                     LT"
     gene            complement(2980..3831)
                     /locus_tag="IVW63_002172"
     CDS             complement(2980..3831)
                     /locus_tag="IVW63_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7860436.1"
                     /translation="MLIEKVLNNNVVITRDERDREMIVMGKGLAFKKKVGDPILDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVHLNDSVYISLTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVIQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            complement(4157..5941)
                     /locus_tag="IVW63_002173"
     CDS             complement(4157..5941)
                     /locus_tag="IVW63_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860437.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRTTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVLVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            complement(5941..7692)
                     /locus_tag="IVW63_002174"
     CDS             complement(5941..7692)
                     /locus_tag="IVW63_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7860438.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSVKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTK
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            complement(7833..8057)
                     /locus_tag="IVW63_002175"
     CDS             complement(7833..8057)
                     /locus_tag="IVW63_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HAP7860439.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            8308..9894
                     /locus_tag="IVW63_002176"
     CDS             8308..9894
                     /locus_tag="IVW63_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAP7860440.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETVEEIE"
     gene            complement(9960..11735)
                     /locus_tag="IVW63_002177"
     CDS             complement(9960..11735)
                     /locus_tag="IVW63_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAP7860441.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVEKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGCLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(11948..12850)
                     /locus_tag="IVW63_002178"
     CDS             complement(11948..12850)
                     /locus_tag="IVW63_002178"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAP7860442.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
BASE COUNT         3835 a         2759 c         2319 g         4135 t
ORIGIN      
        1 tttacaaaac attttcaaaa aagttataat ttacgtaaaa aaataagaag aaggtatcta
       61 catgttatta cgtgaaaaaa tcaaagaaat ctccttttct ccttcagaaa atgaagtgat
      121 ccagtttctc ttaagcgatt ctccagcact tggcgaaatg accatccaag cgatagctga
      181 gcgatgttat gtccacccgt ctacactcat ccgtgtagca aaaaaaatgg gttttgatgg
      241 ctgggtcagt tttcgtaatg cttttttagc tgaaacagcc tatcttgaag ggaattttca
      301 agacgtagat gcgaatcttc ctttttccac cacagacggt attatgacaa tcgcaaataa
      361 aatggcttct ttagaacaga tgacgattca tgatacactt tctctcattc atcatgacca
      421 actgcaaaaa gctaaatatt tactgctcca ggcaaaaaaa atcgtgatct tcgccagtaa
      481 ctcgaatact ttgatttctc aagatttcat gctgaaaatg aagcgcatca aaatggatgt
      541 cacaattgtc accacttttg gtgaatcatt ctatgaagcg tacaattgta cgagcgatat
      601 gtgcgggatt ctgatttctt atacgggtga aaacaatgtg atccttcgta ccgcagaaat
      661 attgaaacaa aatgatgttc caattttagc tttgaccagt atcggtgatt caacgctatc
      721 tgcaatgagt acagccgctt tgcgacttac gacacgcgag cgactgtatt caaaaattgg
      781 taattttacg atcaatacat caatttgtta tcttctagac gtgttatata gttgtgtttt
      841 tgcagaaaat tatcaacaga atttagtcca tctaatttct gtcggtcaaa aattcgataa
      901 acgccctatc agctcagcca tcatgaaaga gcctttcaat tttgaaaata aagaagtgga
      961 ataaaaagaa tagttaagcc tagtccattc ttcacctaac cgttcaggtc agtgcggtga
     1021 taagtgcatc gtctggcccg accgtctccc cttggttttc caaaatatcc aaataatccg
     1081 tgtaattggt gacgatcaca ggtgtttcta aactgtatcc ttccttttcg attttctttt
     1141 tgtcgaagcg tagcaacaga tcgccttgtt tcactctttc tccttgctgc actaagcttt
     1201 caaaatattt cccttccaac tgcacagtat ccaatccgac atgaatcagc aattccagcc
     1261 ctgtttcaga aaccattccg attgcatgtt tcgtcgggaa cagggtcata actgttccgt
     1321 caaaaggggc acgtacttct cctttttcag ggtagattaa gattcctcga cctagtgttc
     1381 cttgtgcaaa agctgcatcc ttcgctgcat ttagtggagc gatttgtcct tgtatcggtg
     1441 tttttacaat ttctttacct gattttttct gtatagcatc tgtttcacct gcttcatcct
     1501 tccaaaagaa aaaagtcagc gaaaacccga ttaccgaagc aatagcaatg ccgataaacg
     1561 cttgaaacat accactggcg tctgtttccg tgatgtagtt taccacccca aaaatcccta
     1621 atccgcccat tatgtagctg attgttccag atgccatcaa atagattcct gaaacagcac
     1681 caccaatcat cgagtaaata aatggcttct tcttcggtaa ggtgattcca taaatagccg
     1741 gttctgttac gccgaagatt cctgaaatca cagctggcat gcaaagcgcc ttcatttttt
     1801 gatccttgaa cttgaaatac atcgccaata ccactgctgt ctgtgcaaaa ctcgcgccat
     1861 aaacgcctac taacatctga ctccacccat tttgcgctag ctgcataatc gcaagaggga
     1921 taatactcca atgaagtccg aaaatcacca gtacttgcca aagaaaccct agaactgcac
     1981 catacacagc tggagaaaag tccatcaatg cttggaatcc cgtgcttaat agatctgtca
     2041 gtatactgac aatcggaccg ataatcaaaa agccagcagg aagtgcgatt aataacacag
     2101 aaaaagaaac caaaaaggtc tggacgactg caggaatcca tttcttggca attttttgga
     2161 cttgtccggc aaatgcgata atgaagataa caggtacgac gctactagta taactgctgc
     2221 ccacccatgg gatacccaaa aatgtttcat aagccggaag acccagcaag ctataaggcg
     2281 caggactgcc atcagggaaa ccactttgta gtgctgctcc ttgtacagtc ggataacaaa
     2341 gtgctgcacc aatcacgagc cccaccatcg gattcagatg aaattttttc gctgctgtgt
     2401 accctaagat cactggcatg aaataaaaaa ttgcatcccc tatcccattc agcatgatgt
     2461 acgtacccga tccttcagta taaaatttga gaaacaagaa caaagcattt aatcctttga
     2521 ccattcccgc tgcagccaaa gcacctaaaa aaggctggaa acagccactt aatatgtcga
     2581 ttaatcgatt gaacagatta ctacttgaag aaacctcttc ttctgcttca tcggaaatcc
     2641 cggctactgt cagtacttct gcatagacat ctggcacatg attcccgatt acaacttgat
     2701 attgcccgcc gcttttcatg atggtgacta tcccttccat ctttttcaaa acatcatcct
     2761 ttgctttatt ttcctccttt agtttgaaac gaagtcgcgt cacacagtgt gtcaagctac
     2821 ggatattttc ttttcctccg atattcttta cgatgttttc tgctaattcc tggtattttc
     2881 ccatttctat tccctccaat taattagtgg aaggtttagc caactgaatg tcactaccct
     2941 tatttcatac gttcttgtta atttgtcctc cttttttatt tatttacaac gattctcatg
     3001 cactaaacgc gcagtatgga tcgttaaata cattttttca tccgtggaca tctggtagtc
     3061 gaaagccccg gttaaaaagt ctgctatttt ctcaacgcaa ccaaacgtat ccttatattt
     3121 tttttgaata acttggaaca attcctcaga aacttctcca tcttctgatt tcgctccatc
     3181 taggacacgt gtcagaaaaa aacgcaggtg tgtgacgaat cgaaaaaagt ggactgaatc
     3241 ttcatcaaat gtaatcttat agtaatagcg gacgatattt aaaatatcct gtattgttgt
     3301 ggtaaacagg taggtattgt cttgctggct ttgaatgcct tgtgcattga ctaaatgcaa
     3361 tgcgataaat ccggcttcgt cttctgataa cttgatgtgg tatttatccg agattttctt
     3421 cactgttttt ttcccaatgg catactcttt aggaaacagt tgtttgatat catacagcaa
     3481 tacatttggc acaaagatcc ccattttttg acgttcgata gctgtataca agtgatccgt
     3541 caatgaaata tacacagaat catttaaatg gacttgcaga gcctcttttg tatattcaat
     3601 gatttcacaa gaaatttcta agtactcaag aggaatcgct tgtgccaatt cttggaactg
     3661 ttgtgaaagt ccgtcatttg tcaactgaaa ttttttgtcg atgcatgagt caagaatcgg
     3721 gtcacccacc ttctttttga atgccaatcc ttttcccatc acaatcattt cccgatctct
     3781 ttcatccctt gttattacga cgttgttatt cagtactttc tcaatcagca tgttttgctc
     3841 ctttccatga tatatagggc tgtatccaaa acaaaaagaa aaacccaaaa agccgtccat
     3901 gaaaccatgg gagactcatc aggtttagct tgcatcaggc aatcactatc caagttgtat
     3961 cgttttcttt atattatcga aagcaaacga ttttgtcaac gctttcttag gggctattag
     4021 gcacttctga ctagctgacg tcgtcttttt taaatctggt aactacgaca ctaactctca
     4081 cagatgaaaa atatgggaag ctatgtttta ttttcactct agtgcttagg tcaaaatgct
     4141 actgtcacaa catcttttat ataccactac tttgcagttt gtacatatct gcatacaaac
     4201 cattttgcgc tagaagtgtt tcatgattcc cgcgttctac tatatgacct ttgtctaaaa
     4261 ctaaaatcaa ttctgcatct cgaatcgttg acagccgatg ggcaatcgca atcgttgtcc
     4321 gtccttgtcg cattttcgcc aatccttctt ggatcaatcc ttctgtttca gtatcgatat
     4381 ttgctgttgc ttcatccaat actagaattt taggatcagt cacgattgtt cgcgcaaaag
     4441 tgatcagctg tcgttgtcca ctagaatagc tggcaccatg ttcgatcact tttgagtgat
     4501 atccttttgg taattcatcg atgaatttgt ttgcttgaac aaactcagcc gcatggcgta
     4561 tctgttcgtc tgtgatagct ggattcatca tccgaatatt tcctgcgata tccccataaa
     4621 acaagaaagc atcttgcaag accagcccca ttttcttacg taactcttcc attggatatt
     4681 ctcgaatgtc atgatcatca atcaatatct gaccttcata aaattcgtaa aaccgcatca
     4741 acacattgat gatcgagctt ttcccacttc cggtgtgtcc cactaatgca acggtttctc
     4801 ccggattagc aacaaaagag atattgttta atacattgtg ctctccatca taagaaaagc
     4861 ttacattgcg aaactcaatc ttacctgaag taatcatttg atctgctcca gggttttgtt
     4921 gtggtgcata ttcttccgta tccataatct tcaagatacg actaccagca accatcccat
     4981 ctgtgaagat gctcaaaaag tccatcattt gagacattgg attaaaaaat ccctggacat
     5041 aagtcgtaaa tgcatagatc agtccaactt ctacgggaga atgcaacgca tcgatcccaa
     5101 ataaagtcaa cgccaacgca atcgccaatg catatagaaa attgatgatc ggacttaaca
     5161 gaatcgaatt cgttttgatc atcgcatagc gcgtgtctaa atactcattg ttcacttgtt
     5221 caaattcttt agctaaacga gcttcttggc gaaactgctg gataatacgc atgccggaaa
     5281 tcgattcatt caattttgta ttcagctgac ttaatttttc ccgcatattt cggtaaatac
     5341 gagaactaaa tttctggtaa taccagatga caattcctaa aatcggcaag aacaccaaag
     5401 tccacaaggc aatttctcca ttgatttgaa acatggcaat gaatgaagaa acgactgcaa
     5461 agatcccagt caataccatc aaaaagacgt accaaaattc aaatagcgtt tctgtgtcat
     5521 tcgtcactcg agaaacggtt gatcctgccg gtgtctgatc aaaataacgc atacctagtg
     5581 tatgcagctt ttcaaataat tttaccctaa tatactgata ggtcttcaat gaagccatgg
     5641 aatacaaata ccattggaaa aaccaaatga tactttttac taggactcca aataagtaca
     5701 taccagcaaa aaacaaaata acttgtgtcg tagccgactg tttagccaga tgatcatcca
     5761 taaaagtttg gatgatcctt ggcaatagga cattgatcac agacagagca aacgcaaata
     5821 agatagcaac gatgaacgtt gttctaaaag gtttggcgaa cttcatcagt cgtttgatga
     5881 tctttttctg ttctttaagt ggaatcgatt ttgtccattc cgattgataa ttttcatcca
     5941 tcaggcctcg cctccttcta tcttcgcttc taattgctgt ttctcccaca tttgttcata
     6001 ccagccgcct agtgcaagca gctcatgatg ggttcctcgt tcaatgattt tcccttgatc
     6061 gacaacaatg atttcttttg catgcatcac gctacttaaa cggtgagctg caatgatagt
     6121 tgttttctct tttcttattt cttttaaatt atgcaagata gcttcttctg ttttggcatc
     6181 tactgcagaa agtgcatcat ctaatattaa taattcagga tttttgatca atgctcgagc
     6241 aatcgaaatc ctttgtttct gtccgccaga taaagagact ccacgttctc caactaaggt
     6301 atcataacct tttggtaatt ccttgatttc attgttgata aatgctaaag aagccgcatg
     6361 ctctacttct tcttctgaaa gttttggatt agaaaaacgg atattatctc gaatggtcat
     6421 cgaaaacaag aagtgatcct gaggcacata gccgattgat cctaataaag cattcaatga
     6481 atattctttg atcgaacgtc cgccaaattg gattttccct tgataatcat cgtattcacg
     6541 catcagtaat ttgatgatcg ttgtttttcc cgcaccagtt ttcccaacaa tacctaatgt
     6601 ttctccttct tggattgcaa acttgatttg ttctaatgct ggtgattctt ctttcggata
     6661 attaaaagag gaaatagcta cattcagctc gccttttgcc ggggtctgca ctgcacccag
     6721 ttgttccacg atatgcgttt tttcatgcaa aagttcattg acgcgatcat aagaagcatt
     6781 tcctctttcc aatacgttga acaatcgacc aatcgcaaac atcggccaaa caagcatacc
     6841 gatataacta ataaatgaga ccatctgccc gatcgagatc gtgccttcca agacatactt
     6901 tccacctaaa ataattgttg caacataaga cagaccgata atcaaggtaa tgaatggatc
     6961 aaataaggag tctagaaaat tgactcgttt gtttttaata attgcatctt caatcttttc
     7021 ttcaaaatcc gctagatctt ctttttcttg tccaaatgtt ttaatgactt tgatcccagt
     7081 gatactttct tgtgtcttat cattgatact agaaaaagct tcttgcgaat cacgaaaagc
     7141 atcatggagt ttcgacccca gcactcgtga agtgacggcc agcaaaggca gaggaatcag
     7201 cgcaatcagt gttaagcgcc aatcaataaa caaaatcatc gcaatgatcg ttgttccgcc
     7261 cgtaatcact gaatctgcaa aggtcaagat accagctcct gctacattct ggatcgcatt
     7321 caaatcattc gttgcatgag ccatcaaatc cccagtccga tatttttggt aaaagagatt
     7381 gtccattttt gtaaaatgtt tgaataactg ctgccgaagt tctttctcca accgagctgc
     7441 acttccccaa atattcgtcc gccagatata acgaaaaaga tattgtaaga aagcagcgat
     7501 aatcaatagg aagatccacc cgaaaatgat ctttactgat aaatttttat cggcaatctc
     7561 atcaatgatg atcccaatca cttttggagg aactaactgt accaaggcca ctgcgaatag
     7621 cgagaaaacc ccaattaaat aatgtttctt ttcctgacga aaaaaccagc ctaactttct
     7681 aaaaatcgac attttactcc tcctttgtct ttatcaagag cctaggattg tctgtgcttg
     7741 tctttttgct gaataatctg aatagtctaa caaattacaa aataaaaaac ggactgaaaa
     7801 aatcagcccg taaaaagtcg ttgggtcaga acctattttt tcccttggtt cttcatttgc
     7861 tgcatcatct ggcgaatttt cttctcagat ggtttttgtc ccattgacat catcattgat
     7921 cgcaacatgt cctcattaac gggaggattt ttttctaaat agtctttcat atatttacgc
     7981 gctaggaaaa agccacctac tgcgccgatt agcaaagcaa taatagcaat aagtacgaca
     8041 atacctgttg ataacatata aatctctcct ttctatttcc gaattgctct caatgactta
     8101 ttttactaaa gtttattgaa aaaagaaagg cgtattcttt agtttcatgc aaaaaatagt
     8161 ggttttttta gaggagaaca aaatttcttt cgtcatctag caagacgagc cacaaaaaaa
     8221 aattaggcat accgaatatt tttctttaat tttttctttt tgaggtgtag aatgtaatcg
     8281 tagataaata ggaaaggtgg ttttttcttg aataatcaat ccaataaaca atttcataag
     8341 catcgactta ttgaacatac aaatggttta tctttagctg aagtaaatgg aacagttgat
     8401 gtaccaaagg ggaaaagttt ttttaaaaca cttcttgctt actctggacc aggtgcatta
     8461 gtagcagttg gttatatgga tccaggtaac tggtccactt cgatcactgg tggacaaaat
     8521 ttccaatatt tattgatgtc agttattttg atgtctagtc tgattgctat gcttttacag
     8581 tatatggcag caaaattagg aatcgtaacc caaatggatt tggcccaagc aatccgagca
     8641 cggacaagta agacattggg tgtcatttta tggatcttga ctgaattagc cattatggca
     8701 acagacatcg cagaagtcat tggtgcagca atcgccctct acctgctctt tgatattcca
     8761 ttagtgattg ccgtctttat tactgtatta gatgttttcg ttctcttact actgacaaaa
     8821 gtcgggtttc gtaagatcga agcactggtt gtctgcttaa ttttcgtcat tttattcgtt
     8881 tttgtctatc aagttggctt gtctaaccca gattggcaca gtttatttgc tggctttatc
     8941 cctaacagcc atacattctc cgactcacct gtcattggtg gcgaaactcc gctgactgga
     9001 gctttaggga ttattggtgc aacagtcatg ccgcataact tatatcttca ttcagcagtt
     9061 tcacaaactc ggaagatcga tcaccaagac gaagaagatg tagcacaagc tgtacgtttt
     9121 tctacttggg actctaatat ccaattgtcg atggcttttc tagtcaatgc gctgctattg
     9181 attatgggtg tcgctgtctt caaaaccggt tctgttcaag atccttcctt ttttggtctg
     9241 tatgaagctt tatctgatcc atcagctatg agcaatggta tcttgattgc tgtagcaaaa
     9301 tctggtatct tgtccacttt atttgctgta gcacttcttg cttctggcca gaactctact
     9361 attactggta cgttgaccgg tcaagtcatc atggaaggat tcatccatat gcgtatcccg
     9421 atttggctaa gaagactggt cacacgattg ctttctgtga ttcctgtatt gatttgtgtt
     9481 ttgtttacaa gtacaaaagg aacgatcgaa gaacataccg ctttgaataa cttaatgaat
     9541 gaatcccagg tgttcttggc ttttgcgttg ccgttttcga tgatcccttt actgatgatg
     9601 accaacagcc aagcggagat gggtagccga tttaaaaatt cattcatcgt aaaacttctt
     9661 ggctggttct ctgtgattag tctaacttac ttgaacttac gaggattacc aggacagatc
     9721 gaaagtttct tcggcgagca agccacttcc gctcaactag cattggctga tcacatcgct
     9781 tatgtaatca ttgttcttgt ccttctcctg ttggcatgga cgattggtga tttatataaa
     9841 ggaaacaaaa aatatgaaca gcgtttgcag gaaacggtag aagaaatcga ataaaaactg
     9901 atttttccac acaaagaccc ttgatagtta ggttaaaaat ctagctacca agggtctttt
     9961 tatttagaag ataaagcttt tttcagattt aatttactga aaactagcat gcttgttact
    10021 acgatgaatt gcgttaacgg cacgcctgcg ccagtgtaga cacttaaaaa ataatccttt
    10081 ttttctggcg cataagaaca aaaccacgag acaccgaaaa gaaaaaccaa ttgtgtcagt
    10141 attaatccgg tgaccacaat caaagaggaa ctataatagg cacgatcagc ttttgcaaat
    10201 acggttccta gtatcataag taatatccct gctattgaag caatcagcac gggaatagcc
    10261 agaacttggt aaatttttat gatgacattc gcgacttttg ctgattttgt taattggaaa
    10321 ttaggtgttc tcggttcatt actatcgatc caattctcca ttagcggaag gtttaataat
    10381 tcttgagcct gtttgacttg ttcttgcgtt ccgaaactat aatttcctcc ttgatggaaa
    10441 tctttatatc gccatgcata agcgtatcct gattgaagga aatcgaatac gattggcaga
    10501 tcactcatcg tctttccatc tcctgatccc atcagataga actctttttt ctttttgatg
    10561 gttcccttgt gataggcttc ttctaattct tggttgactt ttttccaaaa atcattggtt
    10621 tcttttgcat tgttttggta ataaccagat tcgcttacca catctcgcaa tgcccaaaag
    10681 atgatatctc cgggtaattc ttttactttt ccaccttgag tccacgcgtg agtcgtatat
    10741 aattcgtcaa tacgggtaga aacagtatgg aatgtaggag atgcggctaa tgctttattt
    10801 agtgcagcat gtgagaccca tatctcactg ttttctttat tcaagttcgt ttcatcatct
    10861 attcggatca gttgtttcat caaacatcca aattctccac tggaacggtc attgatggtt
    10921 gcaataccgt atgttgtctc atttttatat tcgatccact gatagacgat ggaaaagcca
    10981 actataggaa gtaaaaacaa tgaaagtttc agccattccc gtttcgagag aagaaagagt
    11041 cgttttttta acttctctac ttctttgaaa gaaaagtctt gccctagcaa gatctggacg
    11101 aaactgatac ccaaagctac tacagtaaaa ggaagaagcc agatagaatc ttcgcgaatg
    11161 aaccaaaaga aaggaaaagc gacagaaagc cctaaaaacc atggcagcaa ttttctgcta
    11221 gaaccgtatt tgcggtaata aatagctagt aaacaagcga taatgatctc aacagccgga
    11281 atcacgaggg cattacgata cgttcgagtg gaatattcat gtgtaaaact aatcggagaa
    11341 aacaaaaaat aaaaatagaa acttaaaaga agatacttgt tcttcacgat cggtttaaac
    11401 gcgagtgcaa ccaatatact ggcaaaaata ctgaacatgc cgaacaaaac tgcataagaa
    11461 agatgcagtt tatgtgcaag tactaaaaat aagctgtagg agattccttt ggaaagtgtt
    11521 gtagtcgtat actcccctag ccatttaccg tccaaaatat tttgagcata gcgaatcagc
    11581 agctggtcat cataggttgc cgacatgtct gttccataga ttgctttact atataaatac
    11641 aaacgaataa ttgtaaataa tagggctatg ccaagaataa agtatgtatg tttctttttt
    11701 agttggttga tcaagggttt taaagtgttc agcatctttt cgtccttcca atcacgtttt
    11761 gccacttgct tgtgaaactt ttcgtttttt tacttttcta ccagtatacc ctgtttgtct
    11821 aaatttaaaa agagggggga gaagatgcat gatgaaaaag actgcaaaaa gcactccttt
    11881 gtttcttaaa caaaaaagga caaggcaatg tgcctggtcc ttttttgctg ctgtcagata
    11941 gaaaatctta gagtatcact tcttctgcta ataactcagg aaacacttct ggatcgaata
    12001 tttgtgcttt gaacatggcg atttcttttc catatggtgc gtaagctttc tttttatctt
    12061 tgccgacata gggagtttcc aagattttcg aaatattgtc aaacattgga tcatggacga
    12121 tcttattcag cgtgtcgaat ccgattgttc caaaaccaat attggcgtgc cggtctttat
    12181 gcgaaccttg cggattttta gaatcattga tatggagtac tttaagccga tctaacccga
    12241 tgatcttatc aaactcttcc attacacctg aaaagtcttc tttaatatta taaccggcat
    12301 cattcgtatg acaggtgtca aaagtaacgg ataatttttc attcaatttt actccatcga
    12361 tgatttgcgc taattcctca aatgttcgac cgatttccgt acctttacct gccattgtct
    12421 ccaaagcgat ttgtgccgtc tgttcttttg tcaaaacttc attcaagcct tcaataattc
    12481 tagcaattcc ggcttctgtt cctgccccta catgagcacc tgggtgaagt gtaatttgag
    12541 tagcgcctaa agcttccgca cgaacaatct cttctctcag aaattggacg gcaaaaggaa
    12601 acatttctgg tttgatcgta ttccccaaat taatgatata aggggcatga acgacgatat
    12661 ttgttagacc gttttctgcc atgtacgctt ttccggcatc aatattcatc tcttcgatgg
    12721 cttttcttct agtgttttga ggggcgcctg tatagatcat aaaagtcgaa gatccataac
    12781 tggctgcttc ttctgctgct cctaacagca ttttctttcc gctcatgctg acgtgtgagc
    12841 ctaataacat ggatggattc ctccttgaaa ggcaattgtt actaacaatt cctatatatt
    12901 ggtaagatga tatacaaaga aaatgattga tttttctttg ccctgttctc catagtaact
    12961 gaaattttct ctaaagaaaa gcttaagaac tcttttataa aaaagatcat tttctcacgt
    13021 tttaactcct attatttgtc aaattaag
//
LOCUS       DACCVZ010000074        13036 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.077, whole genome shotgun sequence.
ACCESSION   DACCVZ010000074 DACCVZ010000000
VERSION     DACCVZ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13036
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.077"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(78..150)
                     /locus_tag="IVW63_002179"
     tRNA            complement(78..150)
                     /locus_tag="IVW63_002179"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(115..117),aa:Lys,seq:ctt)
     gene            531..1100
                     /locus_tag="IVW63_002180"
     CDS             531..1100
                     /locus_tag="IVW63_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAP7860443.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1087..1947
                     /locus_tag="IVW63_002181"
     CDS             1087..1947
                     /locus_tag="IVW63_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP7860444.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2137..2841
                     /locus_tag="IVW63_002182"
     CDS             2137..2841
                     /locus_tag="IVW63_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7860445.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2846..4681
                     /gene="walK"
                     /locus_tag="IVW63_002183"
     CDS             2846..4681
                     /gene="walK"
                     /locus_tag="IVW63_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HAP7860446.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4678..5994
                     /locus_tag="IVW63_002184"
     CDS             4678..5994
                     /locus_tag="IVW63_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860447.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5995..6864
                     /locus_tag="IVW63_002185"
     CDS             5995..6864
                     /locus_tag="IVW63_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860448.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6919..7728
                     /locus_tag="IVW63_002186"
     CDS             6919..7728
                     /locus_tag="IVW63_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP7860449.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7831..8460)
                     /locus_tag="IVW63_002187"
     CDS             complement(7831..8460)
                     /locus_tag="IVW63_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HAP7860450.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8630..9922
                     /locus_tag="IVW63_002188"
     CDS             8630..9922
                     /locus_tag="IVW63_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7860451.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9998..10660)
                     /locus_tag="IVW63_002189"
     CDS             complement(9998..10660)
                     /locus_tag="IVW63_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP7860452.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10885..11169
                     /locus_tag="IVW63_002190"
     CDS             10885..11169
                     /locus_tag="IVW63_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAP7860453.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11220..12845
                     /gene="groL"
                     /locus_tag="IVW63_002191"
     CDS             11220..12845
                     /gene="groL"
                     /locus_tag="IVW63_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAP7860454.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4334 a         2252 c         2822 g         3628 t
ORIGIN      
        1 ataaaaaaag aacagcgtaa atgttttcga aatgctttcg caccaacatt tacctgttcc
       61 gtgggtttgg cacccaatgg gccgtgaggg gctcgaaccc gcgacccgct gattaagagt
      121 cagctgctct accaactgag ctaacggccc gtacaaaaag tacttaataa tagtagcact
      181 aagaatttta aaatgcaaga ctacatttaa agaaaatcag aaaaatcttt acttccttat
      241 aggaaatcat tcatagatta ttcacatttg ctcgctatta tataagcata ccaacaaaca
      301 aagttcttgc aagagaacaa accctaacac ttttttcatt ttttactcct ttcccgccgt
      361 ctccccggcg ggtctcctgt tcttaacgat aaaagacaag aaggcttagc cttcttgttt
      421 tttgttttca tggaatcccg ctaatcaaat cacctagtta aagcaactag attgaatgtt
      481 tatcataagt ctgatatcat gtttatgaaa tgaaaaaagg agcggttatg atggaaaaaa
      541 tgcgtcagca attaatggag tgggggaagg aactagaaac attccgtctg cctcactggg
      601 aagaactccc tgacttagaa ctttatatgg accaagtcag aacgttagtt gatcgttatc
      661 tttcacctgt gatacaagga gaaaagcatc cattgcttac ctcttctatg gtaaacaatt
      721 acgttaaact aggtttgata ccagcaccag ttaaaaaaag atataacaaa gaacacgtag
      781 catttttact tgcaatcact acgttgaaac aagtattgac tattcctgaa atcaaagaag
      841 ggatattgtt ccaaggaaaa acagtaggaa ttcgtgaagc ctataatcta ttttgcgatg
      901 aacaagaagc agctgtgtgg atggtcagcc aattagcaca aggtaaatct catccgcaaa
      961 aattcgacca ggcaacccct gtagaatata ttgctgtaag agcggcaact ttatcgtttg
     1021 caatgaaact tcttgcggaa aaaacgattg ttctagaaac cgaatattta aaagaggaga
     1081 aaacaaatga aaaacaataa aatcgcaatt ttagtagatt caggtacgga tgtgccagaa
     1141 gaattgataa aaaaatacga gatgtatatg atcccattga aaattattta taaagatcag
     1201 gtatatacag ataaaattga cattacctct gaagagatct atcaacgttt gccagaggaa
     1261 atccctggta catctttgcc ggatggtgag tcgatcacag aaatctttga gcaaatcaaa
     1321 aaagacggtt atgaaaaggt acttgcggta acaatttcca gtggattgag cgggacatat
     1381 aatgtggttc gtttaattgc acaacagcaa gaagaattgg aagcatatgt actagatacg
     1441 aaaaatattg gtattggtgc aggtttttct gcgatccaag cagcaaaatg gctggaagaa
     1501 ggagtagaat gggatcaact gatcagtaat ctgaatgagt tagtcgaaag aacaaaagtt
     1561 ttctttaatg ttgcgacatt ggaatatctt caaaaaggtg gacggatcgg tttagttgct
     1621 tctattgtag gaaccgcttt aaagcttaac ccaatcatct catgtaatga agaagggatt
     1681 tattacacag taggaaaagc taggggacgt aaaaaaagtt tggataaaac ggttgcttac
     1741 gtcaaagaaa aaatcggtaa tgcaaaggtc ttcaacttag ctgttgccca tggggatgcg
     1801 aaagaagaag caattgaaat ggaagcgaga cttaaaagag agttcccaca agcaaaccaa
     1861 atctactttg gccagatttc tccggcatta gtagtccaca ctggtccggg attattgggt
     1921 gtcggtgtac aagttttaga aggataaatc aaaaaaagga aacactgagg tgaaaatcag
     1981 tgttttcctt ttttattgaa gttagaacaa aaaataataa agtattttgc actttcattt
     2041 taattttctc ttttgtttta taggcaaaga tgaaacaaaa gcagaaatac ggtataatga
     2101 gaaggtatga caataatata taagaggtgg ctctttatga aaaaagtttt agttgtcgat
     2161 gatgagaagc cgatttcgga tatcgtcaaa ttcaatttag ccaaagaagg ctatgatgtt
     2221 tatactgcat atgatgggga agaagccttg gaaaaagttg ctgaggtaga acctgatttg
     2281 attttacttg atttgatgct acctaaaatg gacggcttag aagttgctcg tgaggtacgc
     2341 aaaacttatg atatgccgat cattatggta acagccaaag attctgaaat tgataaagtc
     2401 ctaggcttag agttaggcgc cgatgattac gtgaccaagc cattttccaa ccgagaatta
     2461 gttgcacgtg tcaaagcaaa tcttcgtcgc ggtgccacgg ctgcgaagga accagaagag
     2521 gcagcacctg cggaattgac gattggtgat ttgacgatcc atccagaagc ttacatggtg
     2581 acgaaacgag gagaaacaat cgagttaaca catcgtgaat tcgaactact cttttacttg
     2641 gcgaagcacc ttggacaagt gatgacaaga gaacatttat tacaaacggt ttggggttat
     2701 gattattttg gagatgtacg aacagtggat gtaactgtac gtcgtttgcg tgaaaagatc
     2761 gaagataatc caagccatcc aaattattta gtgacacgtc gtggtgtcgg ttactatttg
     2821 cgtaacccag aacaggagta attggatgaa aagaaaagtc cgcttttttc gatcagtcaa
     2881 ttttaagatc gctattacct ttattctgat tttattgatc tcgatcgaaa ttattggtgc
     2941 ctactttata cgtggtttag aacgttccac gatcaataca tttattaaag atatgaatca
     3001 aacggtggaa tcattagcaa caacaatcag cccggaattg aatcgaaaag ataatgcaga
     3061 tgatgaagag gtaaatgcga atatcaaaag atttattgaa aacagtgcga ctagcgatat
     3121 catcgaaata cgggtcgttg acgaaaaagg gatcatccga ggaacaaccg atgtcaatga
     3181 acaaagcgct gtgggaaaga aaaatgatta tgttgatatc aatgatttca cgactaaacg
     3241 ttatgttgct ttagataacg acgataaacg ggtgaatatc aatgttcaac cgatcctgtc
     3301 cccgaccggc gatgccgtta tcggggctct ttacgtcaaa agtaatatcg aacaaaaata
     3361 ttcggaaatc aataacacag cagtcatttt ctttactgcc tcactaattg cggcatttat
     3421 ttcaatgatc gtatctgttt tagttgctcg ttcgattaca cagccgatcg gtgaaatgag
     3481 agaacaagcc attcgaatcg ctagaggaga ctacagtcgg aaagtcaaag tgcatggaca
     3541 agatgaactt ggacagctgg ctgatacctt caatcagtta gctgaacgta ttgaagaagc
     3601 tcaagataca atggaagctg aacgcaatcg tttggatagc gtgctatccc atatgacaga
     3661 cggcgtcatt gcgacagatc gcaggggtaa agtcattacg atcaatgata tggctgtttc
     3721 cttgctagat atcaaaaacg aggaagcaat cggacaatcg attttgacac ttttagatat
     3781 cgaagaagaa tatacgttgc ggaaattatt agaagatcca aacgaaatgg tacttgaccg
     3841 ttcaaccagt acattggaaa gtgatcagat gatcttgcga gtagactttt ctatgatccg
     3901 tcgcgaatca ggttttatca gcggattagt agctgtcttg catgatgtga cagaacaaga
     3961 aaaaacagaa cgggaacgtc gtgaattcgt ctctaatgtt tcccatgaac ttcgtacacc
     4021 gttgacaagt atgcgtagtt atatcgaagc attgagcgaa ggtgcgtgga aagacgagga
     4081 agtagcacca aattttttga aggtaacgct agatgaaaca gaccgaatga ttcgaatgat
     4141 caatgacctc ttaaatctat ctcgcatgga tacaggtaat acccagcttc aattagaata
     4201 tgtcaatttc aacgagttag tgaattttgt tcttgaccgg tttgatatga tggtgggaaa
     4261 tcaggaaaaa aattataaga tccgtcgtga atttacgcaa agagatcttt gggtcgaagt
     4321 agatacagat aaaatcatcc aagtagtcga taatatcatg aataacgcga tcaagtattc
     4381 accagatggg ggaacgatta cttgtcgctt attagaaacg cataataacg tggttttaag
     4441 tatcaccgat caaggattgg ggattcctaa aaaagatctg aaccgagtgt tcgagcggtt
     4501 ctatcgagta gataaagcac gtgcaagagc acaaggtggg acaggacttg gattagctat
     4561 ttctagagaa gtgattaagg cgcatcgagg cgctatttgg gcagagagca aggaaggaaa
     4621 agggtcgact ttttatatct cgctgccata tgaaccttat gaggaggaat ggtgggaatg
     4681 agaatctctg aaaaagtcgt tcgtatagga ctcattttga tggttgcgtt aagcatatac
     4741 ttctcttatg caatctggct gagcccagca ggaaaaagtt caatcaacgt agatgagaca
     4801 aacactcaaa tgatcgagtc tcaaagcaat cgaaaaactt ccgaagtctt tcttccgctt
     4861 catgttacat ggcaccattc gggaatgatc caagaaacca acagtgaaaa tctcgtgtac
     4921 cgattgcaat tgatcatcga taaagcaaga tttggaaagc tttctgaagt agtttcagga
     4981 gacaaatcac agtttgaaca ggtgaaaaat ctgaactctg gttttgagtt ggcctataat
     5041 gcgccttttt tgctaagaga atacaaggaa gcatttgatt tagatttaga tgtgtcgaac
     5101 ttggcaaaag aaagcgaaaa tatgtatttt actagaatac aattcgatca aggaaataaa
     5161 aaaatccgat ttttgaatta ttcgaaccat ctcgtatatg aagcaaatat ttcgttgaat
     5221 tggacagata tcaataaaga attaacagca aaagacacaa aatggacaga aatgacaaca
     5281 gaaccatcga cgatcgacac gcaatatgct acgaaacatt cgatcaaact gaaaaagtat
     5341 agttatatcc tgtcacagca accctataca ctttttagaa atgctttttt ccagaaacca
     5401 gatagcgtga aaaataatga tgaaagcaat gaattgattt tttacggtgg gaatgaaaca
     5461 atgtctatcc attcggaaac gcaagtagtt gattttcgtg gagagctgcc agagaaaaaa
     5521 gaaaatgcta gtgtattttc tgaaagtttc ccctatatta gcaaattagg cagttcttta
     5581 gggaacctca gatattttga ccgcagtgac aatacgatcg attatcggat attcgtggaa
     5641 ggcttcccgg tttttgggac agacagcaga ggacagattg gtgtggaagt tggcggtgaa
     5701 acgaatggtt ctgtgcaagt gaatatccaa accagtttga atacgattca agtgccgata
     5761 ccttcagacg aagaagtaga acttgcaagt acgaatgaaa tcatccagca gttaaaagct
     5821 aagggagcag atagcaacaa gattggttca gtgatcgttg gctatacatg gcaaaatgtc
     5881 aaagaaacga atcgtgtcgt tgatctctta cctgaatggt atgtgaaata taaagataac
     5941 tggtattcag ctaacgacct tctggaaaaa ttacctggat tggaggcgaa ttaattggat
     6001 ttcaaaaaaa tcgaatggat atttttcgtc gcttttttag ggttgaatgt gtttttattc
     6061 agcagttatc atgacgcggt ataccaagaa aacaatgtca ttcgctctaa tcagactgaa
     6121 tcaatccaac aacgtctggc tagcgacgat atcacttaca cggggaagat ttcgtctgag
     6181 aacaagcaag gctattatct tagcgcggag cagaccaatc ttagcacttc attagcgaat
     6241 tatcgcaagg ctggtaaaag cggcttgctg gcaagtggtg tgtttttaga cggtgatgtt
     6301 ttgacgaaat ctttatccag ttcagatgct gaaaagaacg tgatcgatcc agataaaatt
     6361 agtagttcct tggaagattt tttatctaac aaagacaata ttttattcgg taatgattat
     6421 gtgtacacga aaaacttttc tcatttagaa gaagaaccac tagaaatcca agcaagccaa
     6481 gagtatgaag gcatcccatt caatgatgat acagcaaaaa tcgttctttc tttagaaaaa
     6541 aacgataatg attatagcat cacgaaatac atgcagacgc atttatctga tatcgagcag
     6601 ctgcgcgaaa agacggaact gtatacggaa gaggaagcaa tcaatacatt gtacatcaat
     6661 aacaaaatac caagaggatc aaaaatttta tggcgtcagc tagcttattc ctgtattctg
     6721 aaagtccggg aaaaaaatgt gtatgttcct gtttggcatg tagcgatcga aacaagcgat
     6781 aaagtggtcc aaattgagag tgtcaacgct ttcagcaata cgatcgtgac aaacaatact
     6841 gtaccaaaag tggaagatca ataaaaaagc gagtataatg aaaaaagttt acaaagtaag
     6901 aagggaagta ggagtcaaat ggctgaagaa aaaccagctt ttaaaatcag tatcctagca
     6961 agtggaagtt cgggtaattc actttatatc gaaagtgaaa aaaaacggct tttggtcgat
     7021 gcaggactta gcggtaaaaa aatcacttcc ttgatggctc aaattgatcg gacaccggac
     7081 caattagatg gaatacttgt gacgcatgaa catcgagatc atatacatgg cgtgggtgtc
     7141 ttggctcgta agtatcattt ggatgttttt gccaatcagc agacttggga agcgatggaa
     7201 ccactgattg gaaatgtacc agtggaacaa aaacatctat ttgagatggg gaaagtcaga
     7261 acattcggcg atatcgatat tgagagtttc ggcgtctccc atgacgcagc ggctccgcaa
     7321 ttttatcgtt tccataaaga aaatcggtca ttcgtcatgt tgacggacac cggatattgc
     7381 agtgattata tgcgaggtgt cattgaaaat gccgatggtt atttgatgga aagtaatcat
     7441 gatcttgaga tgttacgcat gggaccttat ccgtggaatt taaaacagcg tattttagga
     7501 gatagaggac atctttccaa cgaagacggt gcacttgtca tgactgatgt gatcggtaat
     7561 cggaccaaac gaatctatct tggccatctt agcaaggaaa acaatatgaa agaacttgct
     7621 catttaacaa tggaaaatgt tttgaaagaa aaagattttg gcgttggaca tgattttgaa
     7681 atctatgata cagatccaga tgaagcaact gagctatttt cgatttaaac agttcaatca
     7741 ataaaaatat aaaaagcaga agataaaatc aatcagggtt ggttttatct tctattttta
     7801 tttttttagc atattaaaaa aataaccgta ttatcgactg actacactga tgtgctgctt
     7861 ttcatgtttc tcatccagta tctcatctac taatgcaatc gcgtaatctg ccatgctgat
     7921 cgtactgtcg ccagcagcgt ttctttgtaa ataatcatca cttaacaaat aagtacctgt
     7981 acgtttgcca tgtggatcaa ataaagaagc tggactgata taagtccaat gtagattttt
     8041 agattgtttc aattttaaca atccttcgta catattgaaa gctgttggat agaagggtgc
     8101 atttttaggt acttggtcaa tcatacgagt cgtcttttct gtatctaaga ataacgaaga
     8161 ggcaccccca acgacaatta agcgtgtatc ggttccttca agcatctcaa tcaaatggga
     8221 caaagaagtt tgatgcattt cttcttttcc tttgggagcg ttgaaagcat caacgacaac
     8281 atcaaaagat gcaagatcag tagttgtcaa ctcaaataaa tccttttgta taaacggaac
     8341 atctgatggc aatttttctg gatgacgcac gattgccgtc acgtctaaat ctctggacaa
     8401 tgcttcgtct aaaataaatg aacctgcatg gccagtagct ccaatgagtg caattttcat
     8461 aaaaaacctc cttttttatt cctgtccatt gtaagcagtt gctgaatatt cgtcaaagaa
     8521 tccgattttt gaaaagctca gtgcgcattc ctttcatggt tcgtgatcat tgggtatagt
     8581 taaattaaga aaactgattg ataaaaatag aagttgaagg agataagaaa tgaaagagtg
     8641 gttagatcgt gcctttttac caatgataac atctgttgtg aatcttagac ccttaactgc
     8701 tttgcgtaat ggaatgactt acacgatccc aataattatt gttggctcgc tgtttttctt
     8761 atttgctcat tttcctgtgg attacatcgc tcagtggata gacaaaacag gattttctat
     8821 gtattttaca caagtatacc aggctacatt tgatgtgata gccttttgga tcgtttttgc
     8881 cattgcatac gcttatgcaa aagaagaaga catcgatcgc ttaccagtcg gcataacagc
     8941 cttgtctgct tatctactgc ttattcagcc actaaatact cagatagata ctgtctggac
     9001 aggtgctgaa gggatactag gagcagttac aactgggctc atcatcggat ggggctatgc
     9061 acgtttagta agacttgcga aagggtggaa gcaaagagag aagatacctg aaaatgtttg
     9121 gcagtctttt acttcattga ttccaatcat tgttatagtc acttttacgc ttatcggttc
     9181 agcggttttt caacagttgt tcagaatgac tgttgttcaa ggagtatgga catatgtcca
     9241 gcttcccatt caatcgttca tagacacgtt gtttggtgtg cttttattag gtttttttgt
     9301 tccgttttta tggttatttg gtcttcatgg atctgcgatg gtcaatgggt tggttagtcc
     9361 cgtcttgcaa gcgaattcat tagcgaatgc agaaatctta gcctcaggac aagagttgac
     9421 ggtggcaaat ggcggacata tcgttactca gcaatttctc gatcagttca tgacggttac
     9481 gggtgctgga ttgacgttag gggctgtatt ttttatgacg gtttttgcga aatcgaagaa
     9541 atacagagaa ttaggaaatc ttgctctttt accagccttt ttcaacatca atgaatcaat
     9601 tattttttcc acaccgatcg tgatgaaccc gatgatggct gttcctttta ttttcgcacc
     9661 ggtcgtttca ggattgatta cctattccgc tttatatttt ggattcgttc ctttatttac
     9721 agcagtccaa gtcccttgga caacaccgcc gatcctctcg ggtttcttag taggcggagt
     9781 gcctgcagcg attttacaag gtatcgtgtt gtcaattagt tttttcattt atttcccatt
     9841 tttgaaaaaa atagattctg caaactgcaa aaaggaaaga cagacaaaaa atgatggagc
     9901 agcagaaaag atgaacgact aaaaaacaaa aatactcctg tcgctttaga ttgggaaaat
     9961 caccaatcta ggatgacagg agtatttata gtcatgttta tactagccct ttttggacag
    10021 ctaattgaac aagaacaact aatgtgttca ttcctacgtg tgtgatcatc gatgtccaga
    10081 tccgaccagt tgctttgtac tctaggctga agaagaaacc taggaaaaag tagattagca
    10141 gatgaccatc attatgagca aacgcaaaca gcaaagagct gatcactgct ccgacccaaa
    10201 aatttgaata tcgactgatg atccccagta tactgcggcg gaatacgaac tcttccatga
    10261 tgggtccagc aacagttgtc gccaaaataa aagcgggtgc ttccatgatc atctggatga
    10321 tattttgtgt attctcggaa ggggttgctt tgccaaacaa tacagattct aacatgacag
    10381 cgatgctttg cagaatcaat gcgacaaaga ttccaaccaa tccataaata acaatctttg
    10441 gagcagaagc tttttttacc gctgattcga tcgctaaggg ttcacgttgc ttaaaataaa
    10501 aaatagctag gacaacggcg cctagtatat acatgactgc agttgctgtg atcaattcag
    10561 acgtagattt tacaagtcct atcgaagcta ggatcaaggg tgagataaaa attagaccat
    10621 agcaaaaaat gctgaggaag ctatattttt ttaaagacat gtaattcctc cttttaaggg
    10681 ataacaagca tgcaaggcaa gcttatatcg attgatttca attatatcat aatttcaata
    10741 agcagctgtc agaataaaat ttcttttctt tgatttaaaa gcttgcaaaa aagagggaga
    10801 atgagtatta ttaaaaatgt aggttagcac tcgaaggtta agagtgctaa cagattaaaa
    10861 aaagagttat cggagggatt tatcgtgtta aaaccattag gtgatcgcgt cattatcgaa
    10921 gtcgcaaaag aagaagaaaa aactgtcgga ggaatcgttt tagcttctgc tgctaaagag
    10981 aaaccccaaa ctgggacagt tgttgcagtc ggtgaaggcc gtttgttaga aaacggtgaa
    11041 aaagttcctg ccgctgtaaa agcaggcgac caagttatgt tcgaaaaata cgccggtaca
    11101 gaagtaaaat acgaaggaaa agaatatctg atcgtcgcag gaaaagatat catggcgatt
    11161 gttgagtaaa tttggaagat aaaaaaataa tcaaaaataa tcaatgaggt gaatcaatca
    11221 tggcaaaaga attgaaattt gcagaagacg cacgcgcagc tatgttacgc ggggtagata
    11281 aattagcaga tacagtgaaa gtaacattag gacctaaagg ccgaaatgtc gtactagaaa
    11341 aatcttacgg ctctccattg atcacaaatg atggtgtgac gatcgcaaaa gaaatcgaat
    11401 tagaagatca ttttgaaaac atgggtgcaa aacttgtatc agaagtagca tcaaaaacaa
    11461 atgatattgc aggagacggt acaacgacag caactgttct gacacaagca atcgttcgcg
    11521 aaggtttaaa aaacgtaact gcaggtgcta atcctctagg cattcgtcgc gggatcgaat
    11581 tggcaacaaa agcagcagtc gaagaattgc ataatatctc aactgttgtt gattcaaaag
    11641 aagccattgc acaagtagca gctgtttctt cgggttctga taaagttgga catttgattg
    11701 ctgatgcaat ggaaaaagtt ggaaacgacg gtgtcatcac aatcgaagaa tcaaaaggga
    11761 tcgaaacaga actagatgtt gtagaaggta tgcagtttga tcgtggttac ttatcacaat
    11821 atatggtaac agataacgac aaaatggaag ctgttctaga aaacccatat atcttgatca
    11881 cagacaaaaa aatctctaac atccaagata ttctgccatt gttagaacaa atcttgcaac
    11941 aatcacgtcc attgttgatt attgctgacg atgtagatgg tgaagcattg ccaactcttg
    12001 tattgaacaa aatccgtgga acattcaacg tagtagctgt aaaagctcct ggtttcggcg
    12061 atcgtcgtaa agcaatgctt gaagatatcg ctattttgac aggtggtaca gtaattactg
    12121 acgatctagg tttagaattg aaagatgtaa caatcgaaaa cttaggaaat gcttctaaag
    12181 ttgttgtaga taaagacaat acaacgatcg tagaaggttc tggagaaaaa gaagcaatcg
    12241 aagctcgtgt gcaattgatc aaaaaccaaa ttgctgaaac aacttctgat tttgaccgcg
    12301 aaaaattaca agaacgctta gctaaattag caggtggtgt agctgttgtt aaagttggtg
    12361 cagctactga aacagaattg aaagaattaa aattacgcat tgaagatgca ttgaatgcta
    12421 cacgtgccgc agtagaagaa ggaatggtct caggtggtgg tacagctcta gtgaacgtta
    12481 tcagcaaagt ttctgctgta gaagcagaag gagacgtggc aacaggtatc aagatcgttg
    12541 ttcgtgcttt agaagaacca attcgtcaaa tcgctgaaaa cgctggttat gaaggatcag
    12601 tgattgttga taaattgaag aacgtggaac taggcactgg tttcaatgct gctactggag
    12661 aatgggtaaa catggttgaa gcaggtatcg tagacccaac taaagtaaca cgttctgcct
    12721 tgcaaaatgc cgcttccgtt tctgccttgt tattaacgac agaagcagtc gttgcagata
    12781 aaccagaacc agcagcgcca gcagctcctg caatggatcc atcaatgatg ggcggtatga
    12841 tgtaagaaaa agcaacttgc ttatctacaa ctgatcatta gtgaaagaca gataaaaaga
    12901 ggctggaaca gaagcgttta actccaagaa ataagaagaa attcacggaa attgcttttc
    12961 aaatttttgt gaatttcagc ttatttccga aggagttgct tctgcttccg ctgtttatac
    13021 gtgtttagag cgtgag
//
LOCUS       DACCVZ010000075        12989 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.078, whole genome shotgun sequence.
ACCESSION   DACCVZ010000075 DACCVZ010000000
VERSION     DACCVZ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.078"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            82..1062
                     /locus_tag="IVW63_002192"
     CDS             82..1062
                     /locus_tag="IVW63_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7860455.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            1184..2602
                     /locus_tag="IVW63_002193"
     CDS             1184..2602
                     /locus_tag="IVW63_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAP7860456.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            2673..4142
                     /locus_tag="IVW63_002194"
     CDS             2673..4142
                     /locus_tag="IVW63_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7860457.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            4152..4619
                     /locus_tag="IVW63_002195"
     CDS             4152..4619
                     /locus_tag="IVW63_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAP7860458.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            4655..5527
                     /locus_tag="IVW63_002196"
     CDS             4655..5527
                     /locus_tag="IVW63_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP7860459.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            5608..8142
                     /locus_tag="IVW63_002197"
     CDS             5608..8142
                     /locus_tag="IVW63_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7860460.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            8298..9071
                     /locus_tag="IVW63_002198"
     CDS             8298..9071
                     /locus_tag="IVW63_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7860461.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            9064..9855
                     /locus_tag="IVW63_002199"
     CDS             9064..9855
                     /locus_tag="IVW63_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP7860462.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            9865..10356
                     /locus_tag="IVW63_002200"
     CDS             9865..10356
                     /locus_tag="IVW63_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7860463.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            10374..10784
                     /locus_tag="IVW63_002201"
     CDS             10374..10784
                     /locus_tag="IVW63_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP7860464.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            10788..12188
                     /locus_tag="IVW63_002202"
     CDS             10788..12188
                     /locus_tag="IVW63_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAP7860465.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            12211..12585
                     /locus_tag="IVW63_002203"
     CDS             12211..12585
                     /locus_tag="IVW63_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAP7860466.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         4497 a         1748 c         2622 g         4122 t
ORIGIN      
        1 ggggaatgag agagtcaagg ttcttggaat gtcgaatagt cgagtaggta gattttctat
       61 ctacaacctt gttgtttaaa aatgaaaaaa attggaatta gagaagttgc gaaagaggca
      121 aatgtttctc ctacgactgt gtcgagggta ttgaatgatc gtggatattt gagtgaggaa
      181 acaaaaagaa aagtttttga tgccatgaaa aaattagaat actatcctaa tgaactggcg
      241 agagcacttt ttaaaaacga aacatatacc gtaggtttga tttttcctac aattactaat
      301 ccatttcacg ctgagttaat tcaagatatc gagttcgagc tttccagcag gggatataaa
      361 gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa aagagtactt gacgatgttg
      421 agaaagaatc aggttgatgg aattatagta ggaacgcaca ataaagatat tgcggattat
      481 gatattccag ggctacctat tgtagcgatt gatagaagtc ttggtgaaaa tacagttaca
      541 gtatcttgtg ataattacag gggtggggaa ttagctactc aactacttgt aaatcatggc
      601 tgtcagaata tactgtgtat tcggggagat agtaagataa agctacccgc gaatagtagg
      661 actttagcat ataaagatgt tttgaataaa ttcatgctgg aaccgttagt cctagaagta
      721 ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta agacatatct ggaaactcat
      781 ccaaatattg acggggtttt tgcaggagat gatttattgg cttctttggc gattaacaac
      841 ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag tgattggatt tgatggagct
      901 caacaaacat tgatttataa tccagaatta tcaactattc aacagcctat agatcaaata
      961 tctaaagtag cagtaaaaaa attattgaat atgattaagg gcgaaaagga gacggatgaa
     1021 ctttcacttc cagtaaagct cataaaaaaa aatacagcat aagttaaatc ggcgaaaaat
     1081 tccttcgtcg atttaaaaat atttttatga aacgggttga catatgaaac gggttgacat
     1141 atattagttg tgaagataaa aaccttttca ctggaggaag aaaatggaga aattattaat
     1201 taaaagcaat aatcatcaac tttactacca acctaaggat gtttgggtcg gagatgttat
     1261 gccttacggg aaagaaggaa aattctttat ttatcatcaa cgtgatacta gaaatccagt
     1321 tccttttgga gaaccgtttg gctgggcttt agcaactacg aaagattttg ttcattttga
     1381 agactttggg gaatctcttt taagagggga tgacaatgag agagaccagt ttatctacgc
     1441 tggttctgta tttgaggcaa atggaaaggt tcacgcattt tatacagggt ataatcgtga
     1501 attcttagcg cagggaaaga catctcaagt gttgcttcat gctgagagtg atgattttgt
     1561 tcattgggaa aaatcagaaa cagcattgga gttagaacca caagaagggt atgatattcg
     1621 aaactggaga gatccatttg tcgtttggga tgatgaaaaa gaagaatatt tgctaatttt
     1681 aggggcgcga aagggtcagg ataaacatct acaaaccgga cgtttagtgg aatttacatc
     1741 aaaagattta actaattggg aattcaaagg tgatttttgg gctccgggat tgtataccat
     1801 gtttgaaatg ccagaacttt tcaagattgg tgactggtgg tatcttgtct attcagaata
     1861 ctcagatgga aataaaatac tctatcgaat gagtcaaagt ttggaaggtc cttggattaa
     1921 gcctaaagat gaagcttttg atggacgggc ttattatgca ggtagaacag cttatgatgg
     1981 aaaacgtcga gtcctatttg gatgggtacc aacaaaagat caagaaaatg ataaaaacaa
     2041 ttatttatgg ggaggtactt tggttcctca tgaagtctat caaaaagagg atttttcact
     2101 tggggtaaaa cccatagacg aagtgtggaa tgcattcata aatttacatg atattgccga
     2161 tgtagagata gaaacagcag acacaagaga agaagtaacg cttgtcaaaa atagtggaac
     2221 tttgtttaat ttagaaacaa caatttcatt tgatgagaat cttagtgact tttcactgag
     2281 attatataaa aaccttgaga cagatgaatc ttacgaatat cgcttcaatt tagatgaggg
     2341 gcgtcttaca tttgataaaa acccttgtta cccttggttt caatatatgg ataaaggact
     2401 tattagacct atatctttaa agcctaacca atcttataaa ctaaaagtga ttgttgatga
     2461 caatataatg acactttata ttgatggaat cgctcttaac gctcgtgtac atggttgttt
     2521 tggtcaagca attactatta cagcaacaaa tggatcaatg actgcaataa ataccaagtt
     2581 ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg caggtctgaa aatcaaacat
     2641 gacctgtcac atttaaaagg gaggataaat gaatggacta caaaaaaatt gccgaagatg
     2701 tattggaaaa cgttggagga aaagagaata tctcaagcgc tacacactgc attactcgtt
     2761 tacgtttaat tcttaaagac aaaagcaaag cgaatatgga aatgcttgag gaaatagaag
     2821 gtgcaaaagg tgttcttttc aatagtggac agttacaagt aattttcgga acaggtataa
     2881 ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc taaggaagta tccgtttctg
     2941 aaatgaaaga cgaaggagtc aataattcag gaaatagact tcaacgagct tttaaagttt
     3001 tctcggatat ctttattccg atcattccag cttttattgg ggcagcaatg gttttaggaa
     3061 ttcgttcgtt gattaccact cctggaatgt ttggaatgga tggctcattc gctgatcaca
     3121 atgtattcct aaatgattta tccaaatttc tgggtattat tgcaaccaca tttgattatt
     3181 taccagtttt agttatgtat tctgcaacaa aacgttttgg cggaaaccct attttaggat
     3241 tacttgtagg atttgttatg attcatccag gactagccaa tcggaatgat ttcgtcatgg
     3301 gaactataaa gcctgattat tggcatttat ttggattaag cattccagca gttgcgtttc
     3361 aagggggtgt ttttccagca attttgactt cttggttttt agcaaaagtt gagaaaatta
     3421 caaataaata ttctcctcaa gtacttgctt acattttagt cccaactgtg acaattgttc
     3481 ttgccaactt tgcactattt ttagtgtttg gtccattggg gaattttatc ggtaatgttt
     3541 taggtggaat cattgatttc ctatatatga agatgggtgc ctttggtgct tttgtttttg
     3601 caggcgcgtt acaaccatta gttgtaacag gaacacaaca tgctattcaa ggtattgagg
     3661 caaacttagt cgcaacaact ggattcaatt atatccaacc tatttggtca gtttcaatta
     3721 ttgcccaagg tggcggttgt attggtatgt atttactctt taagaaaaaa tctaaagata
     3781 gagatattgc gatttcaagc tttattccaa cactggtagg tattactgaa ccggctatct
     3841 ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg ctcgtttatt ggtgctggtt
     3901 ttggtggagc atttatgaaa atttttgatg taaaagccat tggacaagga ttgactgtat
     3961 tgccaggtct gactattgct aatccagttc ttccttatat atttggtaat ctcatagcat
     4021 tcattttacc aatcattttt attctcgctt atgataaata taaagtgttt atccctgaag
     4081 ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa attgccagtt caagtaaagt
     4141 gagatgagag catgttaaat ttttttagaa aaaatgaaat aagcgttgta gcacctgcaa
     4201 ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt cttttcaaaa ggaatgatgg
     4261 gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt atctccaatc gatggttttg
     4321 tttcaagtat ttttcctaca aaacatgcct taggaataaa aacaaaatca ggaattgaga
     4381 tacttgttca tgtaggaata gatacagttg agctaaatgg tgagggattt gatattaaag
     4441 ttcaagaagg acaaaaagtt aaggctgggg atattcttat gaccattaat tttgtagttt
     4501 ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt tccagactac caagacgaaa
     4561 ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga attgtttgtt cttggctaat
     4621 gataagtaat taataataga atcgaggaaa atgtatggtt tttggggcta ttgaagctgg
     4681 tggaacaaaa tttgtttgtg ccattggaga taaagatttg aacatatttg aaaaagtcag
     4741 ctttcccacg actacaccca aagaaacaat gaatttagtt ttagattttt ttaatcatca
     4801 taaagatgat ttagaaggta tcggagtggg atcgttcggt cctattgata ttcattgtga
     4861 atctaaaacg tatggcttca ttacatcaac gccaaaactt gcttggcagg attttgattt
     4921 tattggaagt ttaaaaaagc aacttaatat tccaactgct tggacgactg atgtaaatgc
     4981 ctcttgctat ggtgaatatg tttctggaaa tggcagaggc ctttcaagtg ttgtttacta
     5041 taccgtagga acgggcatag gaggtggcgc tatccaaaac ggaaacttca ttgaaggttt
     5101 tagtcatcca gaaatgggac atatgcttgt aaaacgacac aataaagaca acttttctgg
     5161 gacatgtcca ttccacggag actgtttaga gggcttagct gctggtccgg caatcgaaag
     5221 aagatcaggg aaaaagggac aagaagtgac tgaaaatgac gttacttggg aaatagaagc
     5281 ttattacatt gctcagtgtg catataatac aacattgatg ttatcacctg atgtcattat
     5341 atttggtggc ggagtaatga aacaaaaaca cttaaaaaag aaagtacaag ataagtttat
     5401 tgagttgatc aacggatatg tcgctattcc cgatgttgac aattatatta tgacaccaaa
     5461 attgttagat aattctggta ttgtaggttg tttagcttta gcaagagacg ttaaagaaaa
     5521 atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg gttgatgcga tctttttttc
     5581 aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa tgaaagatga agtattagag
     5641 tatatcaaaa ataatttaaa gtattacgat ttttctgctc aagatattgc aatgaaattt
     5701 tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt tattttcaga tggaaaatta
     5761 ctaaagaatg attctgttag accagtaatg ttcaagtata atcaacaaaa gccaaaagac
     5821 tgcttttcta agtttattgg agcagacata tctttgaaat ccactataga taaatgcaaa
     5881 gctactgtaa tgtatccccc taatggcctc ccattaataa taaaaggaaa cagtggcgtt
     5941 ggaaaaagtt ttttagcaag tttgatctat cagtatgctc ttgatagaaa agtaattcat
     6001 aatgacgcaa aatttgttgt tgtgaattgt gcagattatg caaataatcc agagctattg
     6061 tcagcagttt tatttggata taaaaaagga gcctttactg gggctgaaaa agatactgca
     6121 gggatgctat cttctgctaa tggaggatac ctttttttag atgaggttca caatctaagt
     6181 gcagaaaacc aagagaaatt gtttcttctt atggattctc aaaagtatcg taaacttggt
     6241 gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct tagccacaac agaagataaa
     6301 aatacctctt tgttagcaac ttttagaaga cgcatcccag ctgaaatcac tctgccagat
     6361 tacaataata gaagtacatc tgaaaaaatt caattattat ttgaatttct taaagatgaa
     6421 gcaattacga ttgattcaaa aatattttgt tcgattgaac tttttactga tcttttatcg
     6481 aaaacatttg aaggaaatgt tggagaattg aggaatgaaa tcaagcttct ttgtgcagaa
     6541 ggttatttag gaaataagag aaagtcttca atttatttag gggacaaact agacagcggt
     6601 ttttggatag atccagaaat tagtatagat ttaaaaaaaa tgtttcttaa atcactttct
     6661 gaaattgatt tgattgaact ttttcaaaat cacatttcaa ttgaagaaag catgagtcaa
     6721 ttaagagata gaatacttaa agagtgtgca ggttcttctg agtataatta tttagaaagt
     6781 gacgaattta tagcattaag aaactatgtt gttaataaaa tatcaccaat tattgattcg
     6841 acaggtctat gtttattaga tgaattcttg gcggatatca gtctatttat aatgtttatt
     6901 gatgtaattg aagaaacatc aagaaatttt ttgctgtcta agttcagaaa atttcgtatg
     6961 aaaaatgata aacaaaaatt attggcaaat gagatttgga gtagtttaga agtcgaagaa
     7021 agtaaacaag aacttttgtt gaaatggata ctttttcttg taaagaagtt ctatgtgaaa
     7081 ataccagaaa cccattgtct gatagttatg cacggtaaaa taacagcttc tgcgatcgca
     7141 agggaaacaa ataagttgct gaatacatat gtttatgagg ctttcgatat gccaattgaa
     7201 ggtgagacta gtgacttaat taacctaatc aacaattttt gtaaaagtat agatacgacg
     7261 aatggactca ttctgctagt tgatatggga tcattggaac aaatgtatga aaaaattgaa
     7321 tccaatgtaa taggtgattt ggtaatttta aacaatgttt ctacagcttt agcgattgaa
     7381 tgtgggattc aagtttgcca aaaaaagcca attagtcatt tttaccagat ggattttgat
     7441 tcgtttcaag ttaaagttca gtattataaa ggattatcac aaaagaaaaa tgtaatagta
     7501 tcttgtctct ctggtgaggg gatttctgaa aaagttaagg atattttaaa acggtatctc
     7561 gataatcaag tggagatttt gatttttgat tttaacgcat taaagaaaat agcaaaggaa
     7621 aaagatacta tgatttttaa gaatacaatt tgtgttcttt caaccactga attttacatt
     7681 caaggaatcg attgtttaaa tttagaaaat ctaattaatg ggaatcaaac cttagaaaaa
     7741 ttaaataagt atatggactc ggatagctgt gagttctgct taaatgaatt agttaaactc
     7801 tttactattg aaggcgctag tactaagctt cgctttttag attccaaaaa agtattcaat
     7861 gagatagaaa aagtactata tttgtatgaa aaatattacg atgtcaaaat cccaagtttt
     7921 ctgagaatta atctatttct acatctttct ggaatgattg aacgaattat gattggtgat
     7981 ggaataacaa atgaacattt gaaagaggga gcgcaactat ttgatacttt tttaaatgta
     8041 tcaaaagatt ttttttcaga aatcaaagat atttactgta ttgaaatacc caaaggagag
     8101 tatgagttaa tctatacaat ttttgagcag actattttct aaatagcata ctagcgtcta
     8161 aaaaaatgaa agggtgtcca aagtatattt agacgctcat ttaattaata tttactgtat
     8221 tttcccgctt tattggataa tgttagttgg cacagtaatt gcttatataa aagtataaga
     8281 agaaaggaga gaacaaaatg gcgttttggc aaacattttt agttgtgttg tatggatttt
     8341 tcattaactg ggataaggaa gggcccaaaa tcggaacctc ccaacctgtc gttgcaggtt
     8401 tcttgaccgg acttattatg ggagatattc aaactggact ttatatcggt gggactttgc
     8461 aattaatgac actaggtatt actagttttg gtggtgcatc agtaccggat tatcaaacag
     8521 cagcattgat cggtacttat ttagcaatct caactaacca ggatgcttct ataggaataa
     8581 ctttagcaat accggtagca atgttaattg tacaactaga tgttctaaag tggtcaacaa
     8641 acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa agaagattat caaaaattag
     8701 agtggatgca atatttggca tcaattaata caagctttgt atctggaatt cctgttttgt
     8761 taactgtgat attaggccca acgttagtgg gaagtgcaat caattatatt cctgaatggg
     8821 ttaccggtgg tttaaaggta gcagggggac tattacctgc tgttgggata ggaatgctac
     8881 ttaaatattt acctacaaaa gattactttg cctatttgtt agttggtttc gttttggcag
     8941 tttatttcca aataccaatt ttagggattt cgttacttgg cgctgcaatc gcactaatcg
     9001 tatataaaaa tagatcaaat aatactcaag tagcaccagc tgcaacagga ggttttgacg
     9061 aagatgaata agaaactgac aaaaatcgac aaacaagtaa ttttccggtg gattctcaat
     9121 ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg gttatgcgta ttctatgctt
     9181 ccttttatca aggacacata taaagatgat cctgaaggaa tgaaacaatc cgttttagct
     9241 cacttacaat tttttaacac tacgccgtat acagcgcctt acattattgg tatgaatgtt
     9301 ggaattgaaa aagaagaaaa aaataagtct ttggaagcag taagtgctct gaaaacaggt
     9361 ctaatgggtc ctttagcggg aattggagat agtgtatttg tagttattcc atggactatt
     9421 tttggagcaa ttgcagctaa tatggcattg gaaggtagtt ttgttggaat tattttgtgg
     9481 atactggcat caattttatt aaggattact gcttatcctt tataccttgc tgggaaagaa
     9541 tcgggtgcga gcctactaac tcaaattgaa acaaaattaa agtctattac tgatgcagta
     9601 tcaattttag ggttaatggt ggtcggtgca ctcattgcca cagttgtaaa agtgaatgtt
     9661 ggctttgaat ttaaacaagg cgacttaaca atgaccggaa atgaaatctt tgatcaagtt
     9721 atgcctggtt tattacctgc atgtgtagta gcaattgtgt attatttgtt aggacgaaag
     9781 gttaaaccag tttatgtaat tctattaatc ttagtagttt ctattgcgtt aagagcgtta
     9841 aatattttga agtaggtgtt gaatatggat gaaaaaatga aaggtattat acatgttcgt
     9901 attgatgatc gaatgattca tggacaagta gcaacacaat ggacaaatca attgagtgct
     9961 aacagaatta tggttattaa taatgaagta gccaatgatg acgtaaaaaa agctgtagtt
    10021 cgcctcgctg caccacctaa tgttagaact tcaataatta caagggaagt agcagttaaa
    10081 aatattcttt ctggtaaata tgaaggacaa aaagttctta ttgttgcagt ttctccaatc
    10141 gatgttaaat ttttgattga taacggttta ccaataacaa gtgtaaacgt aggaaattta
    10201 tcaagaagga atggaacaga acgcatccgt ccgacgataa atattactga agaagagaga
    10261 gaggctttta aagaactaat tagtgatgga gttgaagtga cagtgataca aactcctaga
    10321 gattcaaaag aatttttaaa ggattttatt tattaagaac agaggatgag tggatggagt
    10381 ttataattac atctcatgga aatattgcca ttggatttgt agatacatta aaaatgtttt
    10441 ttggcgataa tttaaattgt catgtggtaa cacttggaga tgcaggcatt gaagaattcc
    10501 gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca agaagttatg gtatttgctg
    10561 acttgattgg tggaacacct ttcaacgaat ttgctaaaag aagtgaagta tttcaaaatg
    10621 ggtttcaact tcttggtggc atgaatttag gaattttgat tgaggctgtc aatttgagat
    10681 tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag aaatatgaat acaattgcgt
    10741 gtcttgcaga tatgcaaaga catactaacg aagaggatga gtgataaatg caaaaaattt
    10801 tttacaagcc taaagatttt tggtttgggg attgcatgcc tttttataaa gatggaactt
    10861 tttatctatt tcatcaacga gatacgagaa atcctaaacc tttaactgat ccttttgggt
    10921 ggtcactagt tacaaccact gattttgtga aatttgaaga atacggggaa gtaattcatc
    10981 gtggtggcaa cgatgacatt gatcaataca tttacgctgg aagtattgtc caaggaatca
    11041 atgagtattt agctttgtat actggacata atcgcaaagc taagttggat ggaaaaactt
    11101 cagaagtgtt aatgattgca agttctaaag atttaattca ttggaaaaag gatggcgaag
    11161 cagcaaaact tgttcctcaa gaaggatatg ataagaatga ttggcgcgat ccttttgcaa
    11221 tttttgatca agatcatgga aaatacgttt tgatactagg agctagaaaa ccagcaagta
    11281 agaaaaagcc gacggggaga ttggtctatt ttgaatccga agatttaaaa gattggaatt
    11341 tcaaaggaga ctactgggct aataatgaat ttaacatgat tgaaatgcct gatatatttg
    11401 aaattgatgg aacgtggtat ttactttttt cagagtattg tgaagataaa aagactaaat
    11461 atcgagtcgg agcaggatta ttttcagatt ggaaatcacc agtagacgaa gctttcgacg
    11521 gaaaagccta ttatgcagca agaacagtcg gaactaatga aactggccgt tttctaactg
    11581 gctgggtggc aacaaaagaa ggggagaacg atcaaaataa ctgggattgg ggcggtgcac
    11641 ttgttccaca tcaaattatt caaaagacag acaaaactct tggtgttaaa ctgcctgaaa
    11701 aaataattga gaattttaaa gaaatcactc cattttcaag ttttaagtta gagaaagaat
    11761 ttggaaaaaa agaaagagta attgttccta aaatcgaaga ttattttcta tttgaaacaa
    11821 ctttgactat tacatcgtta acaaaggagt ttgctttaaa attatttgta gatagtgata
    11881 ctcaagaagg atacgaattt cgtatttcat tgattaataa tcagcttact ttcggaaaaa
    11941 ctccgaacta tccttggcct caaatgtttg ataaggggct gcaacgacca ctatttttgg
    12001 aaataggcaa agaatatgaa ctaaagttaa ttgttgatga tacgatagct gttttatata
    12061 ttgataatgt tgctttaagt actagaatgt atgataaagt cggaacagca ttaagtatga
    12121 ctgttacgga gggagcaatc aaggtagata aactagacta ttcaataaat tatgaatgtg
    12181 gattttaaaa caattgaagg gatgatgtaa gtgaaattaa atggtttaca acatattgga
    12241 attccaacaa aagattttgg agcttcaaaa atcttttatg aatccttagg gtttagtctg
    12301 attaatgaag aaatgaatgt gggaagtaaa gtcggctttt tcgagttgaa tggaacgata
    12361 atagaaatat gggaagataa aactactgag tgtagaggag ccattgatca tctagcatta
    12421 gatacggatg acatagatga ggtattcaat tcaattcaag atttaggata tgaattatta
    12481 gataaaaata ttatggaatt accgttctgg gaaaatggaa tccgttactt taatttctac
    12541 ggaccaaatc atgagattat agagataagc caaatgaaga aataaataga taacgaagtg
    12601 ctctaagttg gtatgaacga aaagtacttc attttttggt atcagcattt caatagttta
    12661 atgagaattt actatttcaa attaattcaa agtgacagta ttttttactt atttggtttc
    12721 aaattttgta atccttccta tttattggaa tacactccac attttgtata caagtcatat
    12781 catgttttag caaagctctt accaagcaaa gttataatga tgttttccaa agtttgatct
    12841 ttcgatggag gctaacacat attttttgca ggacagccaa aattagatgt atagaataga
    12901 gtctgtgagg cgtatagaca gtttattgtc tgtatgcctt tttttatttt gaaaaatttt
    12961 tagtattttt cgaaaaatgc tcactccta
//
LOCUS       DACCVZ010000076        12927 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.079, whole genome shotgun sequence.
ACCESSION   DACCVZ010000076 DACCVZ010000000
VERSION     DACCVZ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.079"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            133..3660
                     /locus_tag="IVW63_002204"
     CDS             133..3660
                     /locus_tag="IVW63_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP7860467.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRKENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="IVW63_002205"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="IVW63_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAP7860468.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="IVW63_002206"
     CDS             7448..7789
                     /locus_tag="IVW63_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7860469.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="IVW63_002207"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="IVW63_002207"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAP7860470.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="IVW63_002208"
     CDS             9146..11566
                     /locus_tag="IVW63_002208"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAP7860471.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="IVW63_002209"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="IVW63_002209"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAP7860472.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
BASE COUNT         4394 a         2246 c         2739 g         3548 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtaagga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaac
//
LOCUS       DACCVZ010000077        12901 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.080, whole genome shotgun sequence.
ACCESSION   DACCVZ010000077 DACCVZ010000000
VERSION     DACCVZ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.080"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(116..1564)
                     /gene="cls"
                     /locus_tag="IVW63_002210"
     CDS             complement(116..1564)
                     /gene="cls"
                     /locus_tag="IVW63_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAP7860473.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1716..2609)
                     /locus_tag="IVW63_002211"
     CDS             complement(1716..2609)
                     /locus_tag="IVW63_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7860474.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2593..3279)
                     /gene="ftsE"
                     /locus_tag="IVW63_002212"
     CDS             complement(2593..3279)
                     /gene="ftsE"
                     /locus_tag="IVW63_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAP7860475.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3384..4485)
                     /gene="prfB"
                     /locus_tag="IVW63_002213"
     CDS             complement(join(3384..4421,4423..4485))
                     /gene="prfB"
                     /locus_tag="IVW63_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078989099.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAP7860476.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRGLFDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4611..7145)
                     /gene="secA"
                     /locus_tag="IVW63_002214"
     CDS             complement(4611..7145)
                     /gene="secA"
                     /locus_tag="IVW63_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAP7860477.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            complement(7367..7918)
                     /gene="raiA"
                     /locus_tag="IVW63_002215"
     CDS             complement(7367..7918)
                     /gene="raiA"
                     /locus_tag="IVW63_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAP7860478.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            complement(8046..8765)
                     /locus_tag="IVW63_002216"
     CDS             complement(8046..8765)
                     /locus_tag="IVW63_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAP7860479.1"
                     /translation="MRCSCCSKDIFQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            complement(8762..10075)
                     /locus_tag="IVW63_002217"
     CDS             complement(8762..10075)
                     /locus_tag="IVW63_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP7860480.1"
                     /translation="MNHFWGRRLLTRDIEAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            complement(10156..10476)
                     /locus_tag="IVW63_002218"
     CDS             complement(10156..10476)
                     /locus_tag="IVW63_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7860481.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            complement(10584..10871)
                     /locus_tag="IVW63_002219"
     CDS             complement(10584..10871)
                     /locus_tag="IVW63_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860482.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            10998..11642
                     /locus_tag="IVW63_002220"
     CDS             10998..11642
                     /locus_tag="IVW63_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAP7860483.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            complement(11701..12408)
                     /locus_tag="IVW63_002221"
     CDS             complement(11701..12408)
                     /locus_tag="IVW63_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7860484.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
BASE COUNT         3565 a         2797 c         2244 g         4295 t
ORIGIN      
        1 taatttcgct catgcgagac gctttctcca tttctgacgt actctcagaa atggccccgt
       61 tagaaaagga cacgagatct ccatctgttg atggttctca tgtccttttt atgttttaaa
      121 ggagcggcga aatcaatctt gctaatcctt ctttcatctt gatgattatt cctcggtttt
      181 catacatttc ttttgtgaga tgcgtagaaa ttttcgagtc ttcaaaaaaa gcttttctta
      241 cacgtgaagc cattcgttca tcataaacca gtgtattgac ctcaaagtcc aagcgaaatg
      301 aacgaacatc gatatttgct gagccaactg aaacaatgcc accatcgata atcatcgtct
      361 ttgcatgaat aaatccattc tcatatgttt cgatccttgc tccatactcg atcagctctg
      421 cagcgaaaga atacgttgcc cagtaaacga gaagatgatc tggtttgtta ggtatttgga
      481 tatgaacttt tacgcctgaa agaagagcca acttcagtgc ttcatgaatc gatccatccg
      541 gtatgtaata aggcgtttgg atcaatatct cccgtttggc taacgaaatc attttcaaat
      601 aagtcatttt gatttgttca tgttcggtat ctggtccgct tgtcacgatt tgaacagcta
      661 tatcaccagt agtgtgaatg gacggaaaaa atttgggaga atagcctact tcttttgtat
      721 gctgagaatt ccagtccatc aaaaaacggt tttgcaaggt atacaccgct tctccgtaaa
      781 tacgcaaatg attgtctcgc caataaccaa atttctttac caatcctaga tattcatttc
      841 caacattgaa cccacctgta tatccgattt tcccatcaat aactacgatt ttacgatgat
      901 tgcgataatt gatccgagga ttaatatacg gaacaaatag aggaaagaaa aatgcgactt
      961 ctccgcctgc ttttttcaaa ttctgaaaaa agctggaaga aacttgtgtg gaaccccatg
     1021 catcaagaag gactctgact tttacccctc gtcttgccgc ctctgtcaat gcatctcgaa
     1081 cttcttcacc taatgcatca ctgcgataaa tataatactg gaagtggata tggtcttctg
     1141 cctgcttgat atcttcaatc agcgcatcga atttttcacg accatctgta aataaagtga
     1201 tttcattttt agtcgtatag agcgtacttt caaataccgt gagcatatag atcaattgtt
     1261 tcacatctac ttgtccagta ggcggatgag gataaagccc tcgcatcaat gcctgtttgt
     1321 cttcttcaat ttccaggttc ttaccgattt tcccttggat cttcaaatca aagattttct
     1381 ctttggaaat ccctcttcct aaaaaaatat ataaaataaa tcctacaact ggaatgaaca
     1441 tcaaaacgag cagccatgcc catgtttgag cagtttcctt tctttctcga aaaacgatga
     1501 taaaggaaag caaaatattc ataatcaaaa ggatcgtaaa aaaattgtca acgataattt
     1561 tcacggcttc acctcttctt ctaccaactt aagaataccc aagttgtttt ttaaagtaaa
     1621 gggaaaaaag ccgcttcctt ctattctcct agccaataaa aaaagaaagc tggaacgaaa
     1681 ctgtccaact ttctcatttt atttatattg tggtattaga atttcaagaa acgtctcata
     1741 gaaatgatcg agccaagtga accaatgatc acaccaatgc cgaccattaa aagattgatt
     1801 ttccaaacga tattttgtgg atgaatcaat gaataatggg aacgtaataa tgatggattg
     1861 atcaattgga aaaaccatgc ataaccaaat gtgatgatca aaatcggaag aatcgcaccg
     1921 atcagaccga tccagccacc ttcaaggaaa aacggccagc gaatatatcc attttttgca
     1981 ccgactaaac gcatgatttg aatttcacgc tgtctagaca aaatcgtgat ccgaatcgtg
     2041 ttcgaaatga gaaacatcgc tacgaacagc agcaatgccg ctgcaactaa tccccatgtc
     2101 cgaactgcac cagcgatttg gaaaatccga tctgaggaag ctccaccgta atcagaacga
     2161 gaaacattct tcaaatctgc tgcttcttct gctacttgtt ttgtataaga aggatcagta
     2221 gcacttacta catacacatc atataacggg ttattgtcac cttcaaacaa tttccaggaa
     2281 tcacccattt cgttttggat ttttttcaat tcctgttctt tgcttgaaaa ttcaactttt
     2341 ttaacatgat ctaagtcatt caattctttt tctagctttt tcatctcttc gtcttttgta
     2401 ccgatatcta cgaatacaga tacatcaacg tttccttcta tatcctgagc taatttagtt
     2461 gcattcatga taactgccat gaatacaccg actaaagtca acgtgatcgt taccgcactg
     2521 actgaagcaa ctgtcatcca gccgttacgt ttcaaactct tgatactttc taataaatgg
     2581 cggaaaaagg ttctaatcat cgtatccata ttccccttcc gcttgatctc gaataatgcg
     2641 gccgttttcg atagcaatta ctcggtgccg aatcgtattt acgatcgtac tgttatgtgt
     2701 agccatcacg acagtagttc cttgggcatt gatccgatct aataatttca tgatttccca
     2761 tgagttttct ggatccagat ttcctgtcgg ttcatccgcg ataagtactt taggcgtatt
     2821 cacgattgcc cgagcaatag agacacgttg ctgttcccca ccggataatt cgctaggaaa
     2881 gactcgaact ttgtgtttca aaccaacaag gtccagcact tccattactc gttttttgat
     2941 atctcgaggt tttctgccga taacttgcat agcgtacgca acattttcat atactgtttt
     3001 tcttggtaat aatttatagt cttggaacac cacgccgatt tctctgcgta gataaggaac
     3061 ttcgcggttt ttgattgcta ttagatcatg acctgcgacg ttcaaagttc cttttgaagc
     3121 tttttcttct cgatacatca atttgatgaa tgtagattta ccggctccag acggaccaac
     3181 cacatagaca aactctcctt gttcgatgac aatcgagaga ttgcggatag cggtcgtacc
     3241 atttgagtac ttcttcatta catccttcat ttcaatcatg gcgttctctc catatctttt
     3301 tcagtcttta gctattatag catggcaatg tttcaacatg cttgcaaaat cttacaattt
     3361 tatttcaatt taacaatgag ttcttattgt agatgcattt ttaaatagcc gtcaataaat
     3421 aaatcaaggt caccgtccat aactgcttgg acatttcctg tctctacgtt tgtccgatgg
     3481 tcttttacca tagaataggg atggaaaaca taagaacgga tctgtgaacc ccagccgatt
     3541 tctttttgtt ctcctcgaag tgcagctgct tcttgttctt tcttttccac ttctaattga
     3601 taaagcttag cttttaacat ccccatcgct tgctcacggt ttttcaattg tgagcgttgt
     3661 gcctgactag ctactactgt tcctgtaggc aagtgagtga tccgtacagc agattctgtt
     3721 ttattgatgt gctgaccacc tgcaccactt gctcggtacg tatcgatttt caaatcatct
     3781 ggattgattt ctatatcgat cgtttcatca agctctggca tcacatctac cgaacaaaaa
     3841 gaagtatgac gtcgtttcgc tgagtcaaaa ggcgaaatcc gtacaaggcg atgaacacct
     3901 ttttctgatt ttagataacc aaaagcgtta tgtcctttaa tcagcagggt cacactcttg
     3961 atccctgctt catcacctgc ttgataatct agtgtttcta cttgatagcc atgctgctct
     4021 gcccaacgtg tatacatacg taaaagcatg ctgccccagt cttgggactc cgttccgcca
     4081 gcccctggat gcaattcgac gatcgcattg tttcgatcat aaggtccgtc taacagcata
     4141 gataattcat acgtcttcat tttttcatct aatgcattga tacgtgtttc tgcttcttct
     4201 tgcattgctg catcaggttc ttcttgcagc atctccacca tcaattcgat ttcttctagt
     4261 tcttcggcaa gagaatggaa ttggtcatag gtttctttat tagcgttatt ttcgctgatc
     4321 actttttgtg cggcttcgct gtcatcccaa aaaccaggtt cagccatttt tgcttctgct
     4381 tccgcgatgt cttcttccag ctgatctaag tcaaagagac ctcctgaaac ttgtgacctt
     4441 ttcctgcatt tctgtcagga gatttcgaat ttcggatatt tccatgtttt ttccttcttt
     4501 cactatactt ttttcattat atctagtcta acagaatcag caaataacag aaagaaggtg
     4561 agacgaattc ttaaaaaaag aatttgtctc accaatcctg ctgtcagaaa ttagtttgca
     4621 ttttttccat gacagttctt atattttttc ccgcttccac aaggacaagg atcatttctt
     4681 ccgaccttgt tcacatggat tggctgtttt ttcgcgctag tattactatt ttctttggca
     4741 tctccgtctt ctgagtgaga agctgttcct tgagaaacct gttcacgctg tacgttttga
     4801 cggatctcag ctttcataaa gattcgagtg acttcatact cgatggcgcc taccatatct
     4861 tcaaacatct tatagccttc tgtttgatat tcgactaatg gattgttctg tccataagca
     4921 cgtaagccga ttgactgacg taattgatcc attgcatcaa tatggtctgt ccatttagag
     4981 tccacaacac gcaagatcac gactttttca aattccaaca gttgctctgg accatttagt
     5041 tgagccgctt tggtattaaa tacttcttgt gctcgttcgt ttagatactc tttgatctcc
     5101 tgagatgttt ttccttcgat atctgcaaga gtaatactat cttcatggac aagagtactg
     5161 ccggcaaaat cgatgatact ttccaaattc caattttctt tctctaattg tgtatgcgca
     5221 tctactacac gactgattgt ccgtttgacc atgttcatta gtggcttgga taagcttttt
     5281 tcttccatga ttacttcttg tcgctgttta tagattactt cacgttgttc acgcatcaca
     5341 tcatcgtatt gtaagacgtt tttacgtgtg tcatagttat ttccttctac acgtttttgt
     5401 gcagattcta cttgtttcgt cagcatcttg ctttggataa cagcatcttc ctcaccgatc
     5461 ttcatccgat ctaagaaagc tttgattcgt tctgaaccga atcgtttcat caaatcatct
     5521 tccaatgaca agtagaattg tgacatacca gggtctcctt gacgtcctgc acgtcctcga
     5581 agctggttat cgatacgacg agattcatgt cgttctgtcc cgataactgc tagaccacca
     5641 agttctctta ccccaagtcc taacttgata tctgttcccc gaccagccat gttggtagca
     5701 atcgtcacag cacctttttg accagcattc atgatgatct ctgcttcttt aaagtgattt
     5761 ttcgcattca gcacttcatg aggaatacgt tcttgattca gcatatctga taataactca
     5821 gatgtttcaa ccgcaacagt tccgactaac acaggttgac ctttgcggta gcgatctttg
     5881 atatcttgca cgacagcgtg gaacttgctt tgtaatgttg ggtaaagtaa atctggacga
     5941 tcatcacgga taaccggacg atttgtcgga atctggtata cttggatgtt ataaatttct
     6001 ctgaattctt cttcttctgt tttagctgta ccagtcattc ccgcaagttt cttgtacata
     6061 cggaaatagt tctggaaagt gatcgtcgcc atggttttcg tttcgtcttc gatctctacg
     6121 ccttctttag cttcgattgc ttggtgaagt ccatctgaat aacggcgtcc atccatgatc
     6181 cgaccagtga actggtcaac aatcagtact tttccgtctt ggacaacata atcgatatct
     6241 aaaagcatga tatagttggc tctcaatgct tgatccaagt gatgggtcaa tgcagtattt
     6301 tcaatgtcgt ataagttatc caaaccgaat gtttcttctg ctttttcgat ccctgcttcg
     6361 gttaaactga ttgtttttga ttgtacatcg attttataat cttcttcttc tttcaaacgt
     6421 ttcacgaagt tgtctgctct tgtatataaa gctgtggatt tttctgcttg ccctgaaatg
     6481 atcagcggcg ttctcgcttc atcaatcaag attgagtcaa cttcatcgac aatggcataa
     6541 ttcagcggac gttgtaccat ttgatggcgg taaacgacca tattgtctct caagtagtca
     6601 aatcctaatt cattattcgt actataagtg atatcacaat tataagcctc gcgtttttca
     6661 tccgaagatt ttgagttgat attcaacccc actgttaatc ctaagaaatt ataaagttcg
     6721 cccatttccg tcgagtcacg ggttgctaaa tattcattga cggtaactac gtgtacccct
     6781 tcgccagtca gagcatttag atatactggc atcgttgcgg tcaaggtttt accttcacca
     6841 gtacgcattt cagggatatt tccatcgtga agcacgattc cacccatcaa ttgtacgtgg
     6901 tatggatata accccaatac acgttttgct gcttctcgga cgactgcaaa agcttccgga
     6961 agtaattgat ctaatgtttc tcctttttgg tatctgccct tgaattcagc agtttttgcc
     7021 tgtaattgtt catcagttaa tgctgccatt tggtcagcgt atgcttcaac tttttttgca
     7081 atgctatcta aacgttttag ttctttctta tcgttttcga taagtgaacg aatcaaattg
     7141 gccatgcgtt gtgtaatctc cttttccttc tgtgtattat ccagactatg tagactttac
     7201 ttttcatttt atcattagtt atagataatt gaaatatctt aagcgtatta aagtaagaac
     7261 ttcataattt attcatattt catctaaaag aggaggaaac tcaaaaaaac ttgcggcagc
     7321 tgtcagtagc tgctgcaagt tttcgttgtt atttaagtaa ggctgatcag tctgtttcaa
     7381 tcagtccgta ttttccatct ttacggcggt aaacgatact tgtaccattt gtttctgcat
     7441 cttcaaaaat aaagaagtta tgtcccagca tgttcatttg taagactgct tcttcactat
     7501 ccattggttt caatgaaagg cgtttcgtac gtacgatatc taattcagaa tcattttcgt
     7561 tttcgtcctc ttcattgaat aaagcagcag catctgcagt attcatgccc gtttcacggg
     7621 atttacgatt aatttttgtt ttgaatttgc ggatttggcg ttccaattta tcaacaacca
     7681 aatcgatact tgcgtataaa tctggagaag tttcttcggc acgtaataca agataaggta
     7741 atgggatcgt tacttccact tttgctgttt tttctgtata aacttttaag ttcacatgcg
     7801 ccgttgcatc gggtgcgtca ctgaaatagc gttctagttt gcctactttt ttctcaacgt
     7861 agtcgcgaat cgcttcagtt acttcgatat tttcgccgcg tacattatat ctaaacataa
     7921 aaattacccc tttcgtctac cacaatcaag aaggagaagg accactcttt ccctcttctt
     7981 aattctatta tatcgaactc taggttattt gcaaattaaa tcgctatcaa atttccacat
     8041 ctaattcatc tcgccaaaga aatggttcgg atgattttcg gctgtgcgac ctgcaaacaa
     8101 tctgctgcgt ggaaaagagt ctgtcctgtt gtatagacat catcaataat caatattttt
     8161 ttattttgta tcttagaaaa ggtgactgca agttcaaaag gttgaggcat ctccaatctt
     8221 tcctttcgcg tgttttttgc ttgagccagc agatgcttct ctcttttgag tagcatctga
     8281 aaaggaattc ttgctgcttt caacatctcg cttacttgat tgaatcctct ttctgttcgc
     8341 cttttttcag ataaaggtat tggacaatag atgtatgtcg ggtattcttt ttttatctgc
     8401 gtccatttat atgcaaaggt gcctgctagt cggatatctc ccataaactt gtattgattg
     8461 agccaggcct tcatattttc atcgtacaca aaaaaggcac ggtgctgaaa atcataggtc
     8521 ggatatttct tcttccattc ttgacagtca ctgcagtaaa cgggaataga ctttactttc
     8581 tttttcgtac tctctagatt gaaatggatt ggtttttgac agccagaaca gcctcttgtt
     8641 tccaataaat gaaattgtgc gcgacaaact gaacaagtct gaggtaatct gtatttcgaa
     8701 acaccaataa tctcgctgaa tgttaaattt tggaagatat ctttactgca gcaactgcac
     8761 ctcacagcat cttcttccct tcttcattca tttctttgat ttcctgacaa gcttttcgaa
     8821 tagctgcagt tttttcttca tagaaaaagt atacttgact gttcgtataa ggccctttac
     8881 gatcggctct tcctgcgatt tgtaccaaag aagatttagt aaaaaccgga tgatccgctc
     8941 ctaaaacgat aacggatatt ctttcaaatg tgactccacg ttcaaggatc atcgtggtta
     9001 acagtatatc atattttgct tctcgcattt tctggacttt ttccgcccgc tgattgtctc
     9061 ttgaagaaac atctgtgatc tcatatctcg gaagagcctc ttgaagtgtg gctttcaaac
     9121 gatgcatcat cgtgatactt ggacaaaata aaaggatatg gttttcttta attaattgat
     9181 gaatgatccg caccaaagat tttatcttct tcttgttctt gcatttttgt cgccaattat
     9241 tcatgaaaac caagacgggt tcaggaagca aacgccgatg aaagcgtaaa gcaagtttgt
     9301 ggatgtcaaa cgtctgcttg atttccttta gtaacttttt atcaggtgtg gcacttaagt
     9361 agatgaatcg tccgtctggt ttaatcgctg tttgcacagc atgagctaat cctgcatccc
     9421 cgttataagg aaacgcatcg atctcatcga tcactattaa atcaaaggac cgataaaaac
     9481 ggtatagctg atgaatcgta cagataacaa aagaagtaaa ggtataagcc gttgctgtat
     9541 tcccatggag caacgtgatt ttttcttctg gaaaaacata acgatagcgt aaaaacaatt
     9601 cattacaaac atcgactcgc ggtgtacaaa tcgctactct tcctccagct tttaaagttt
     9661 ccactaaaat aggataaagc atctctgttt tccctgcacc tgttacagcc caaataagat
     9721 gatgtctttt ttctgaatgg caaagtattc tctttgagat ttccgtttgt ttttcagtaa
     9781 gctgtcctgt ccaaaaaaag acgacttctc gaggttttgc ttcaggctga tcaaacaaat
     9841 ataaatcttg ttgagtgtcg catcgcccta aatatagaca atgtgtacaa aaataaccgt
     9901 aatctgcaag ctgtccatca atgacggacg tcctcattcc acagcgatga caaagaatcc
     9961 agttgcccaa acgttccact gctgcgatct tctcataatt tggtaaattt acctcctcac
    10021 agtctattgc ttcaatatct ctcgtcagaa gccttctacc ccaaaaatga ttcatattct
    10081 tcgccctaaa aaaatatacg aaaaaacaag cgatctattt tttggatcgc ttgttcgata
    10141 gttatactgt tctatttatt cacctatgag cgtgattgct tgatctaaca ctttttcgcc
    10201 attcatcata ccataatcag ccatattgat gacatctaaa ggaatgcctt ttggttccag
    10261 acgtttctca aaatcagctt tcataaagcg aacttgtggg cctaataaca acacatccac
    10321 gtctttattt gcaaggttgt tatctgcgtc agaagcggac acagcgaaaa tatccgagtc
    10381 gattcctttt gcttcagcag ctttttgcat ttttgttact agtaaacttg tgctcatacc
    10441 agccgaacat acaagcatga ttgttttttt agccatactt ttctctcctt tttaaaacaa
    10501 actatgcaaa cgttttcttc gcgtctgtta ctctattata taaaaagaaa gaaatttgtc
    10561 aacgttttct aaacgcggtt tatttaatca aatagccaac tagatttcac taatttattg
    10621 aacacgacat attctttgtc caaattgatg acaactactt catagcctgc atttatccag
    10681 ccataggcac ctttttcagg gtgtttataa tcatttgccc accaatctgt actttccctt
    10741 gctgttttgg gaagtccgtt actgggaaac agcagttcgt caaattgggt aaaggtcaac
    10801 gttacttgag agccgccatt gttcttcaaa taatgcgtaa ttgcatcgta ctttttcatt
    10861 cgttcctgca tccccagatc cacctgcctt tgtctttatt atcgcatact acagcaattg
    10921 cgcaaccgtt acagtgttga aacaacctag aactttattt atactgaata aagaaaatga
    10981 aaaaaagagg tgacaagatg atcgagcgct atcgtacaat aaaagaaaat ggacaaagtg
    11041 agattgagat caaaaaatca cgctttatct gttctcttag acgaatagaa tcagaggacc
    11101 aagcaaaaag tttcattcaa gaaataaaaa aagaacattg gaaagcgaac cataactgca
    11161 gcgccttcat cattggagaa aaaaatgaaa tccagcgaag cagcgatgat ggagaaccaa
    11221 gtggaacggc gggcgtaccg atgttggaag tcctcaaaaa aaatcaactg atcaatgtag
    11281 ctgcagtagt cactcgatat tttggaggaa cgaaactcgg cacaggcgga ttaatacgag
    11341 catacactca tgcggtctct caagcattgt ctgacattgg aatcgtagaa ggtaccttgc
    11401 aacaggagat ctctgtgatg atcacgtatc cgcaactagg aaaattacag aattatcttg
    11461 aactccaaca tttttttata aaagaaatcc aatatactga tcaagttagc gtcatctgtg
    11521 ctgtagatga aaaaagtgct gaccacttta aagaatccat cattgagctg ctgaacggac
    11581 aagtccaatt tgaagagggt tctgtttctt atcacgagca actgataact gatcatatat
    11641 aaaaacaggt gattctgatt ctcttttatt tctaataagg aatcagggat cacctgtttt
    11701 ttatttttcc aaataaaact caaaacgatt tcctacgtat tgcgtacgca catactcaaa
    11761 cggcgtaccg tcttcaaaat aagaaatctg gcgcaaacga agaactgcat ctcctcgttt
    11821 tacctctaaa tagtcagcaa ttttctcaga agccaacaca gcagtaatcg tttgattcgc
    11881 tggaccgatc tttttcccgc ctttttcttc tagcgtgcga tacaacgatt cagtaatctc
    11941 tgctttgctg tagccatcga tcagcttttg tggaacactg gcaacttcaa aacaaatagg
    12001 gacatcatct gcgaaacgaa tacgttccat tcgcaagatc gtgtcatctt tactcaagtt
    12061 tagtttttcc atttcacttg agcttggcga agtcaagaaa taagagattg tccgactaga
    12121 cggtactcga ttttgtgatt ccataatttc tgtaaaactt gttgcaccag acattttttc
    12181 ttgtactttt tctcgcgcaa catacgtacc cgaaccgatc tttctttcta agattccttc
    12241 atctgccaag ttttgaattg cttgtctcaa cgtcatacgg ctgacattga atttcactgc
    12301 taattctctt tctgaaggaa gacggtctcc gactttccat ataccctgtt cgatttcatt
    12361 ttttaattgg tcatgaatct gtatatatac aggtaattga ttcgacataa cgtacacccg
    12421 tcctttcgtt tcttctatta taactggtat atacctgatt cacaactgaa aaagataaag
    12481 gtttctatcc atcaacagag gatttagaca cacatcgttc tccctactcc tattgtcaga
    12541 aacaattttt tagatatgtt caacctagaa aataacaaaa gaccctaaaa tcgatgaaaa
    12601 tgccgactta tggatctttt gttattatta gcggttttta gccatccatt tttttgtatg
    12661 attcgttggg cgttttgatt ttacctggac cgcttttccg ccttttttcg gaatattcac
    12721 ttcaatattg tatttttctg atttgaccaa atcatataac ttttcagctg cttcgtctac
    12781 tttttctttc catttcatgt ggatccctcc aattcttgta gttaacttaa ctctatctta
    12841 attcagcaga atcttcaagg aacaaggtag caaagcaaaa aaaagagctc tcgaactaac
    12901 g
//
LOCUS       DACCVZ010000078        12861 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.081, whole genome shotgun sequence.
ACCESSION   DACCVZ010000078 DACCVZ010000000
VERSION     DACCVZ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12861
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.081"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..135
                     /locus_tag="IVW63_002222"
     CDS             <1..135
                     /locus_tag="IVW63_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP7860485.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
     gene            complement(313..2310)
                     /gene="tkt"
                     /locus_tag="IVW63_002223"
     CDS             complement(313..2310)
                     /gene="tkt"
                     /locus_tag="IVW63_002223"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAP7860486.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2412..2663)
                     /locus_tag="IVW63_002224"
     CDS             complement(2412..2663)
                     /locus_tag="IVW63_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HAP7860487.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2810..3433
                     /gene="lexA"
                     /locus_tag="IVW63_002225"
     CDS             2810..3433
                     /gene="lexA"
                     /locus_tag="IVW63_002225"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAP7860488.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3613..3831
                     /locus_tag="IVW63_002226"
     CDS             3613..3831
                     /locus_tag="IVW63_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860489.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4120..4632)
                     /locus_tag="IVW63_002227"
     CDS             complement(4120..4632)
                     /locus_tag="IVW63_002227"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAP7860490.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4646..6943)
                     /gene="recJ"
                     /locus_tag="IVW63_002228"
     CDS             complement(4646..6943)
                     /gene="recJ"
                     /locus_tag="IVW63_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAP7860491.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7085..7519)
                     /locus_tag="IVW63_002229"
     CDS             complement(7085..7519)
                     /locus_tag="IVW63_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HAP7860492.1"
                     /translation="MKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPLILV
                     IIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQREFRN
                     ERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7529..8317)
                     /locus_tag="IVW63_002230"
     CDS             complement(7529..8317)
                     /locus_tag="IVW63_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7860493.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8314..9255)
                     /locus_tag="IVW63_002231"
     CDS             complement(8314..9255)
                     /locus_tag="IVW63_002231"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAP7860494.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9432..10019)
                     /locus_tag="IVW63_002232"
     CDS             complement(9432..10019)
                     /locus_tag="IVW63_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HAP7860495.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10240..11553)
                     /gene="obgE"
                     /locus_tag="IVW63_002233"
     CDS             complement(10240..11553)
                     /gene="obgE"
                     /locus_tag="IVW63_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAP7860496.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11841..12851
                     /gene="gap"
                     /locus_tag="IVW63_002234"
     CDS             11841..12851
                     /gene="gap"
                     /locus_tag="IVW63_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAP7860497.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
BASE COUNT         3568 a         2877 c         2279 g         4137 t
ORIGIN      
        1 ttcaaccaag tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa ccatatccct
       61 agaaaatcac taaattacca aacaccatta gaagtttttt tgagttacgt aaatggaaag
      121 ttttgtctcg cttaatttga caaataatat tctcaagaaa cacaaactaa tccgaagaat
      181 tctttgtttt gtcatttaaa tgtaacatag ccgaaaacga aaagtaatat tgatttattc
      241 ttctaacaca taaagaacag ctgtctccaa cttgcagaca gctgttctta tcagtcaaac
      301 aattgcttgg atctatgata gttgattgta cgtattcacg acattttcta ctgtaaatcc
      361 aaattcttct aaaattttag tgccaggggc agatgcaccg aaatgatcga ttgtaatcgt
      421 tgcgccctct gttcctacgt agcgttccca tccaaatgat gcagcagctt cgatagccac
      481 acgtttcttc actgatttag gaagtacact ttctttatat tcagaagatt gtttttcaaa
      541 gaggtcaaag cttggcatag aaacaacaga aacatctttg cctttttcag ccaattcttt
      601 ttgagctttc acagccaaat caacttcaga acctgttgca atcaaaatac cttctggtgt
      661 ttctccttgt gatggagaaa gaacatacgc gccttttttc accatttcat ctgctacttc
      721 ttttgtagaa ggcaatactg gaaggttttg acgactcaat acaaggatag taggcgcatc
      781 tgttgtctcc atcgctactt tccaagcagc acgtgtttca tttccgtctg ccggacgaat
      841 cacttgaaca ccaggcatgc agcgaacaga tgctagttgt tcaatcggtt cgtgcgttgg
      901 tccgtcttct ccgacagcaa ccgagtcatg tgttaagacg taaacaacag gagtatgttg
      961 gattgctgct aaacgaactg ctggtcttag ataatcgaca aagacaaaga atgttccacc
     1021 gtagatacga gttccgccat gaagttggat accattcata gccgaagcca ttgcaaattc
     1081 gcggacaccg aaccagatgt tgcgtccttc ataatgttca ggagtgaaat ctttatctgc
     1141 agccaccatt gtattattgg aacctgacaa gtccgctgaa ccaccccaga agcttggtat
     1201 agctttcgat aattcttgga tgacttcttt acttgaaaca cggcttgctt gactgcttcc
     1261 aacttcataa gttggcaatt ctgcatccca gttttctggt agtttgccat caaaagcatc
     1321 ttcaaattgt tgtgctaatt caggataagc ttttttataa ttggcaaaca tttcattcca
     1381 tgcatcttca gctttttgtc cttcttctat catcgtttga tggaagcggg cagctacttc
     1441 ttctggaaca gtgaaatctg gatactccca accataaact tctttagcca tcttgatgcc
     1501 atcttcacca agaggagcac catgaacagc agatgttcct tctttaggag caccatagcc
     1561 gatgactgtt tttacttcga tcaatgttgg tttgtctgtt tcagcttttg cttcttcaat
     1621 cgctttagag attgcttcta ggtcatttcc gtctttcact aagatatgtt gccagccata
     1681 tgcttcatag cgagcaccaa cgttttctgt gaaagctttt gaagttggac cgtctagtga
     1741 aatatcgttt gaatcgtata aaacgatcaa tttccctagt ttcatatgac ctgccatcga
     1801 acttgcttct tgagataccc cttccatcaa gtctccgtca ccgcatattg catacgtata
     1861 gtgatccatc acattaaagt tttctttgtt atacgttgct gcaaggtgcg cttctgccat
     1921 tgccataccg acagccattg caatcccttg tcctaatggc cctgtagtgg cttctacacc
     1981 atctgtatga tgtacttcag gatgtcctgg tgttttagaa tcccattgac ggaattgttt
     2041 caaatcatcg attgtcactt gatagccagc taaatgaagc aagctataca acattgctga
     2101 cccatgtcct gccgaaagaa cgaaacggtc gcggtcagcc cagttttttg atgtcgttgg
     2161 atttactttc aggtgttttg tccataacgc atatgccata ggtgctgcgc ccatcggcaa
     2221 tccaggatgt cctgagtttg ctttttggac tgcttcaata cttaatgtac gaattgtgtt
     2281 aacgccaagt tggtcaattt tgtcaaacaa aataacccct cctattaatt taggtttttt
     2341 ttacctttat ttcttacact ttcattctat aagatgtcac acgaaaaagc aatctttttc
     2401 agtatttttt actaaaagtt gtcatttcgg ttgtgtaagc cttttttctt ttggatttct
     2461 tttaattttt ccggggtcac gtcattgccc tcaggatcga cgactttcat tccttcgata
     2521 tgatgacgca taccggaacg aaaagcttcc aaatactctt tgcgcaagtt gatttgttct
     2581 tgttcttcgg cttttgagag accattttcc ttctttttac gtgcaagttc attgatccgc
     2641 tctatttttt caggtgacag catgctcagc cctcctttta ctctccttca tattatataa
     2701 aaactgaaaa aaaaacaact agataaacta aataaaatac gaacattcgt ttgatttagc
     2761 gctttttata tggtactatt tatttatcaa gtgaaagaag gtgtaccttg tggcccgaca
     2821 aactgaatca agacaaatcg aagtcttacg atatatccat gaacaagtaa cccaaaaagg
     2881 atacccgccg actgtccgtg aaatcgggga agctgttcag ctttcttcta cttctactgt
     2941 tcacggtcat cttgcacggc ttgaaaaaaa agggtttatc caaagagatc cgacgaaacc
     3001 tcgtgcaatc gagttgacaa aacaaggttt agaaaagatt gggattcgtc caacaactat
     3061 tccagtactt ggcgtcgtaa cagctggaga acccatttta gcagtagagg atgcttcaga
     3121 cttctttcca atccctccta atctttcttc cgaagaaggc agtctcttta tgctgacaat
     3181 tcgtggagat agtatgatca atgctgggat attggatggt gacaacgtga tcgttcggaa
     3241 gcaagaaact gctcaaaatg gcgatattgt cattgcaatg actgccgagg acgaagcgac
     3301 ttgcaaacga ttctataaag aaaaaaactt tttccgtctg cagcctgaaa acgacttgct
     3361 cgaaccaatc atcttagatc aagtatctat attaggacga gtagtaggac tttatcgtag
     3421 tcatatctat taattgctac taattaaaag aaaacttttt aaaaagagtt tgagacgttg
     3481 gtctcaaact cttttttcgc ccgggttctt cttctttcaa atttttatca cttccctctt
     3541 tacaaaccga acaaatattc gtatactaaa tatacgaaca attgttcgca taaattaaag
     3601 aggtgagaat tcatgaaatc aatgagacgt cttggcttag tattaactgt tttgttttta
     3661 ggtattatta ttggtaattt cggcatacgt ccagctttac ttgtgtttgt tccgttattt
     3721 actttgtggt tcatgttgtg ggatgaaaag aagtaccgtc aatctgagcg gcgcagaatt
     3781 catgaagatc atttctatca tgagccctac tacagatcca ggcaatcata ataaggattg
     3841 actgctaatt attcaaaaga caagaagtta aacttttacg ggggtgtgac aaaaatcggt
     3901 cacatccttt ttttcgaata aacggtgttc taaagccagt ttttcggtat taagtcaaat
     3961 tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat ttataaaaaa
     4021 atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt taaaatcgct
     4081 tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca ttaatgtaat
     4141 gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga tcaaaaatgc
     4201 gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt tgattgttcc
     4261 tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa tggcatcctt
     4321 atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga tggtttctcg
     4381 aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat aagcaacagg
     4441 acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc gtttttcttt
     4501 tgcataattt acgatttgtt tagtagcttc ccgataagcg tcaccatctg ccatcagtgg
     4561 ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg caatataatc
     4621 ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg gtaggaatat
     4681 cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgtcgctgg tataatctgc
     4741 tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg ttctctattg
     4801 taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt tcagggatac
     4861 gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct tgagaatgga
     4921 tcaatttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa taggcctcat
     4981 caggtgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa acttctttca
     5041 gatccgctaa atcatctgga caatccataa caactagaga gtttggtttt cttttttcaa
     5101 ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg ataatctcag
     5161 gcacgaattt caacgtcgaa gaatcaaatg ctaaataaag gctaccttcc gacgttcggc
     5221 tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc acagaaaaat
     5281 cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa agctttccta
     5341 ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca aaagcgaccg
     5401 catcaagctg actcgatgca tcggaaagga caaatttcag atgctgttgg tttgctccga
     5461 ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa ggattatccg
     5521 taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact tcatttggca
     5581 gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga tgatcgacta
     5641 tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc gttaaaccga
     5701 ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca agcatttcaa
     5761 aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct tcttttaaag
     5821 taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca atgcccaaaa
     5881 cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta ttgaccatcg
     5941 ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg atctcattca
     6001 atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac gagacggcag
     6061 gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa aaaccgatcg
     6121 ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc tgaagtccta
     6181 tccgttctga atgatgaatg gcatcgattc ctaatgaaac aaggattcga ttctcatcag
     6241 tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat tctgcaggcg
     6301 gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc aaatctggaa
     6361 atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct ggtaaattct
     6421 caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga gcgtatgcta
     6481 ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt ccttcttcga
     6541 tcttttcttg gtataccgat tggtttggtc catacccatg ctcaaatcga tttggcagga
     6601 atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt gcactggtga
     6661 tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt acagcttctt
     6721 ggattcggct gattgcttta tccatatcgt gtatcagata cggatcatgt aattcttgtt
     6781 cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt tgccacagta
     6841 acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag gattcagaag
     6901 gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca ctcctaactt
     6961 agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa aaacagatca
     7021 gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt atgaaatatc
     7081 cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt tcttccggcg
     7141 ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa gcagcttcca
     7201 actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct tcaattttct
     7261 tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt tgcttttttt
     7321 gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc agcgcagaac
     7381 cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt acaggaacat
     7441 ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat ccaagaatca
     7501 cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg ctggctaaat
     7561 aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa ataaacggtt
     7621 gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc aacttggcag
     7681 gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca gccttatcga
     7741 agaaatttgt ctcgattgga cctggattca ctgtcgtaac agctacgcca agtggtttca
     7801 attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca gaataaaccg
     7861 ttgattttgc agttgccatt tttccagcca tagaggcgat attaatgata tgaccttgtc
     7921 ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct aagatgttga
     7981 cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg aaaatcccaa
     8041 aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc ttttcatata
     8101 attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc tctttgccgc
     8161 tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt gcgcaactta
     8221 taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga ccgcctgaac
     8281 tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct cgcgaaatgg
     8341 aatctcaatg ctatcaaaat ctttcataat cgtcgtgttt tcaaacactt cttgtgcttc
     8401 tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag taagtagcag
     8461 ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg aatggaaata
     8521 gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca gaatatcgct
     8581 attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa tagtcacgat
     8641 tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc catcttctag
     8701 ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa tacctaattc
     8761 ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac gataaccaaa
     8821 actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat cagtaaaaat
     8881 cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg tttgcgaaat
     8941 acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct ctaatggcgt
     9001 atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa tatgatcgcc
     9061 gtgtaaatgt gtaatgaaaa ttttaccgat ttttctcgga cgaatagtcg ttcgcaaaat
     9121 ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct cgtctaaaag
     9181 tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac ctgttcctaa
     9241 aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt ttagggtaaa
     9301 aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa cgttctaaag
     9361 cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt gagatcctct
     9421 gctgtttttt attaatttga agatccagaa ctttcattgt cgttggaagt ttgcggatgt
     9481 ttgtccttcc aagtcttttg tgcagcttct ttcgcatgat tttcagcttc tttcgcatca
     9541 tgcacatctt tttcgacatc ttcataatcc aagcgagtaa tttctccgcc taattccatc
     9601 attaccaatt gattcagtgg gcgattgtcc tcttcatcag caatcaagat cagtcctgta
     9661 gctccttcac cgattttatt tcctacaaag tcgaacacgg tctgggcatc ttttatttct
     9721 ttggcatctt gtgtcgcacc gatcattcct ccggcaaacc atcctaataa aatccctagc
     9781 ggaccaccta atacaccaac caacattccg attaatccac ccgtagaaga tttgttatta
     9841 ccggtaaagt cgataaaatc ttctattttg aattgatgtg tcccattagg atcatggctg
     9901 acaactgcca tctgttctcc tttaatcgaa cgaacagcat gtaacttttt gatttctgaa
     9961 aatgcctgat atgcctggct ttctacttga aaatttaaaa tgattactcg tttgctcatt
    10021 aaaaacgccc ctttcatacc ttcttgttat ttattttacc tttaattgaa aaataagaaa
    10081 agaaaagcac tctttttttc caataaaata gggctgtgac aaaagtcgta tcacagctcc
    10141 tttttccgaa taaacggcgt tcttgaagct gatcacttct gtcacaacct cccttaaatc
    10201 tgaatctata ttttttggta tttgttttta tttgcttgcc tattcgacaa attcaaattc
    10261 aaactcaccg atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa gagcttcatc
    10321 cacacccata ccacgtaatt gacgagcaaa acgcatcact gtttcatcat gatcgaaatt
    10381 cgtcatttgg aataattttt cgatcttctc accagataag atccacgttg catctgaatc
    10441 acgatcgatt tggaactcag gaccttctgg attgaatcca tagtgtacag tttcttcttc
    10501 cagttcttct tcgtacaatg ggaattctgg cgttacttct aacaaatctg ctgtagcatt
    10561 caataacgcg tccaatcctt gtcgagtcac tccagaaatt ggaaatactg ggatgtcatc
    10621 agcaaattca tcttcttttt ccttgttcag ctgttctttg aatttcacta gattttccgg
    10681 tgcatccggc atatccattt tgtttgccac gatgatttgc ggacgctcta gcaagcgtaa
    10741 gttataagta gataattctt tgttgatggc aagatagtct tcataaggat ctcgtccttc
    10801 catcccactc atatcgatca catgtaaaat tactcgtgtt ctttcgatat gacgaaggaa
    10861 ttgtgtaccc agcccaacac cttgcgaagc tccttcaatc aagcctggca agtctgctgc
    10921 ggcaaaactt ctgccatcac ttgtagtaac cattcctaga ttaggtacga gcgtcgtgaa
    10981 atgataagcg ccgatttttg gacgagcaga tgaaataacg gatagtaaag tcgatttccc
    11041 gacagatgga aaacctacaa gtccaacgtc tgccaatact ttcaattcta gttcgatttt
    11101 tcgctcttgt cctggttcac cgttttcagc aatttccggt gcaggattcc gaggagaggc
    11161 aaaacggata ttccctcgtc caccgcgtcc accttttgcc acaactagtg tttgaccatt
    11221 ttcaattaaa tctcctaaaa gagcaccagt ctccgcatct cggacagtgg ttccttgtgg
    11281 tactttaaca taggtatctt ctgaaccacg accgtgcatc cctttactca tcccattttc
    11341 acctggctgc gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac gtaacccttc
    11401 atcgacgatc aagatgacat cgccgccacg accaccgtct ccgccagccg gtccgccgtc
    11461 aggaacgtat ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc cagctttcac
    11521 atcgatcgtt acttgatcta aaaacatgga cataattaag tcctcctatt attcatttat
    11581 ttatttgact gcctgaattt ccacaataaa caaaagtctt acttatttta tcggtgaaat
    11641 ctgattttgt ctatcatttc agcaaaaaga ttgtttacct tcttcttttt ttatcatttg
    11701 gtaaggtttc caaccttttt tctgctacca agtataattt tttgacaaaa tattctttgc
    11761 gtagcagaat aacagtgtat taattgtatt aattgaggat gccgtttcac agcaccccta
    11821 ataaaggagg aacttttgat atgacagtaa aagtaggtat taacggattt gggcgtattg
    11881 gccgtctggc tttccgccgc atcaaagaag tctcagatga tattgaagta gtagcaatca
    11941 acgacttaac aagtccaact atgttagcac aattattgca atttgactct actcatggta
    12001 cttatcctgg cacagttact gcaacagaag actcaatcgt agtggatggc gaagcaactc
    12061 gtgtttatgc agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac ggtgtagata
    12121 tcgtactaga atgtactggt ttttatacat ctgaagaaaa agcaaaagcg catttagatg
    12181 ctggtgtcaa acgagtagtt atttctgccc cagctggtgc tatgaaaacc atcgtctata
    12241 acgtcaatga tgatacatta gatgaaaacg acaaaatcat ctcagcaggt tcatgtacaa
    12301 caaactgttt agcacctatg gcttatttct taaataatga atttgggatc gaagttggta
    12361 caatgacaac agttcatgcc tacacttcca cacaaatgct cttagatgga cctgtaaaag
    12421 gcggtaattt gcgtgctgct cgttcagctg ctgacaatac tatcccacat tctactggtg
    12481 ctgcgaaagc aatcggctta gttatccctg agctacaagg aaaattacaa ggacacgcac
    12541 aacgtgttcc agtcgttgat ggttcattaa ctgaattggt ttcagtattg aaaacaaaag
    12601 taactgctga tcaagtaaac gaagcaatca aaaaacacac agttgacaat ccttcattcg
    12661 ggtatgatga ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa ggttcgatct
    12721 ttgacccaac gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt aaaactgttg
    12781 catggtatga caatgagtat ggatttactt gccaaatgat tcgcttacta gaaaaattcg
    12841 ctaacttgta atttgataga t
//
LOCUS       DACCVZ010000079        12735 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.082, whole genome shotgun sequence.
ACCESSION   DACCVZ010000079 DACCVZ010000000
VERSION     DACCVZ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.082"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            94..537
                     /locus_tag="IVW63_002235"
     CDS             94..537
                     /locus_tag="IVW63_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7860498.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(543..1727)
                     /locus_tag="IVW63_002236"
     CDS             complement(543..1727)
                     /locus_tag="IVW63_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HAP7860499.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            1995..2693
                     /locus_tag="IVW63_002237"
     CDS             1995..2693
                     /locus_tag="IVW63_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAP7860500.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2700..3377
                     /gene="nth"
                     /locus_tag="IVW63_002238"
     CDS             2700..3377
                     /gene="nth"
                     /locus_tag="IVW63_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAP7860501.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3503..4036)
                     /locus_tag="IVW63_002239"
     CDS             complement(3503..4036)
                     /locus_tag="IVW63_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860502.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4333..6714)
                     /locus_tag="IVW63_002240"
     CDS             complement(4333..6714)
                     /locus_tag="IVW63_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAP7860503.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6704..7351)
                     /gene="recU"
                     /locus_tag="IVW63_002241"
     CDS             complement(6704..7351)
                     /gene="recU"
                     /locus_tag="IVW63_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HAP7860504.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7415..7954
                     /locus_tag="IVW63_002242"
     CDS             7415..7954
                     /locus_tag="IVW63_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HAP7860505.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8044..8463
                     /gene="gpsB"
                     /locus_tag="IVW63_002243"
     CDS             8044..8463
                     /gene="gpsB"
                     /locus_tag="IVW63_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HAP7860506.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8485..8852
                     /gene="rnpB"
                     /locus_tag="IVW63_002244"
     ncRNA           8485..8852
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="IVW63_002244"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9061..10227
                     /locus_tag="IVW63_002245"
     CDS             9061..10227
                     /locus_tag="IVW63_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAP7860507.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10273..11769
                     /locus_tag="IVW63_002246"
     CDS             10273..11769
                     /locus_tag="IVW63_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HAP7860508.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11850..12533
                     /locus_tag="IVW63_002247"
     CDS             11850..12533
                     /locus_tag="IVW63_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP7860509.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4273 a         2229 c         2630 g         3603 t
ORIGIN      
        1 tggtttcaga ttgggttttc ctacaaaata tttttatctt tgttgaatag gaaacaaaaa
       61 aacaatataa tgaaagaaaa agaaggtgta gaaatggata aaagacaact gctaatagaa
      121 gaatatctgg atttagctaa tgagattatt catcgtaata aaccagaaat ggaaaaagaa
      181 tttgcaggat ttactctaaa tgaactagaa gtgattgaac atatcgggaa aatccctgat
      241 cctaacgtga caaaattagc gaatgctagt tacatgacta gaggagccat cagtaagcta
      301 acaaaaaaac tgatagctag agggatcata aacacttatc aaagcgaaga gaataaaaaa
      361 gaaatctatt ttcaattgac gccaatcgga caaaaaataa ggaatagaca cgagcaactc
      421 catcaaaaat gggtacagcg agatgctact gtatttgaaa atatgtcaaa agaagaattt
      481 gacacagtat ttcgttttat cggtcgatac agagaattta tacgaagtag caaatgaagc
      541 tactattttt tattgtagtg ataataggca aaaatcataa gcaaaaatcc gaataccgtc
      601 ggaagaaatg gtgctgcagc ataaagctgt cctgcgatta gcgggccgat gacgcgcgat
      661 agagattgta tactttgggt accgcccatt acaagacctt gctggttatc tgagacagaa
      721 ttggatagtt ggccattgaa tacaggagta aaaatagaat caccgaaacc ataacagata
      781 atcccaaata aaaacaaaat cggcagtaga agaattccag ataatgtgat gaatagatag
      841 gcgaggattt cactgaacat ccctattctt gtgatctgct gttctgaaaa ttttttgagc
      901 aatcgaggca taatgaacaa ttgcgagaca gtatccaaga ttccaatcaa agagaagctt
      961 aaaccaacca acccagcctt ccactgaaag gcgtcaatcg aaaattgaga aaagatagat
     1021 tgaagagagc cagctgccaa ccaaacagca aaacctgctg tcaataaagg aataacggat
     1081 gaaatcttga ataattgttg taattggtga aaaggtctta catgggagaa acttaaatct
     1141 actgaacgtt tttttattgg aaggctttct agcataaatg tgtagccata aacggcattt
     1201 aagaaagtaa agagtgctcc aataaatata ggaacagaat tccccaactc agctaataga
     1261 ccccctataa taggacccag cgttgttcct ataccgacta aagcacccat ccatccaaaa
     1321 actttggttc tttcattagg ttccgtgatg tcggcaaagt aagcatataa ggtggagatt
     1381 tctcctgccg tcaatccttc aatgatacga ccaaggaaca acatccatat cgaatttcct
     1441 aaaccaaaaa gcaaatatcc gatacttgat cctaataaac tgataataag gatcggatga
     1501 cgcccaaaat gatcacttaa gctaccgaga atgggggcag ataagaaggc agctagagca
     1561 taaacagaca tgagcaaagt gatatagaaa gcttgctgat gtatggagtg agaataaggc
     1621 agcgttaaaa acggaagtac aggactgacg atagtaaatc ctaatccagt gaataagaca
     1681 gagacgtatc caaaaacttt agaatgttta tttgtgaaac tgtacatgta aaaactcctt
     1741 tatgcaataa tgttaacttg gaaacaaaaa tagtgtatag taattttgtt tccttgtcaa
     1801 cattctaagg aacagcgaaa tctacttaat ttatttattc cgaaaagtga agatacgcat
     1861 caaaaacatg aacaaacaaa aatcaagtag acgacattgt aaatctgacc gatcagtgaa
     1921 gtaaatagaa aagaaacctg ttcttgcttc ccatgttttt tttacgtata ctgtgattga
     1981 gcggaggaga aatcatgttg aatttagaaa attacttaag cgctggacaa acagtcatat
     2041 ctaatctttt acttaaaaat tatcatagga tcggtctaca atctgaagaa tttttatttg
     2101 ttctacagtt gcatatggca cagcttgaag gagatacttt ccctgatttg cagatgattg
     2161 ctatggatat gggaatcaaa caagatcaga tttttcaaat actggatcgt ctcgtaacaa
     2221 atggatttat caagatagaa acgacgattg tcaacggtaa aaaagcagat cgatataatc
     2281 tttaccccat ctatgatcta ttaggtgagt atttaaaaac acaagaaaaa aaatacgaag
     2341 aaaaaacaca agaaaaagaa atccagtcag tgtatcaatt atttgaacaa gaatttggac
     2401 gcccgctttc ttcgatcgag ttccagcgga tcggacaatg gctagaagaa gaccattatc
     2461 agccggaaat tttgaagcta gcactgcggg aagccgtatt aaatcaggct tatagtttta
     2521 attacgttga ccgcattttg ctatcgtggg aaagaaaaaa tctacgtaca aaacaacaag
     2581 tggaagaaga ccaaaaacga agaaaacagc agcttcttca aagagaagta gaacagtcag
     2641 ctcaacaaga agaattgccg aaagtctcac tgaaaaattg gttggaggag tagcggaata
     2701 tgttaagcaa acaaaaaaca atggaagctc tagaaacgat gtatggaatg tttcccgaag
     2761 cacatggaga actcaagcac aataatccat ttgagttatt gattgcagtg atcttaagtg
     2821 cccaggcgac agatgtatca gtgaataaag caacgccaga tttgtttgcc tcttttccga
     2881 cacccgatgc gttagcagaa gcttcaatcg atgaaatcat tcttaaaata aaaacgattg
     2941 gtttgtatcg aaataaagca aaaaacatca aagcgtgtgc acagcagctg attgaacgtt
     3001 tcgatgggca agtgccaacg tcaagagaag aattgatgtc tcttcctggt gtaggcagaa
     3061 agacagcaaa tgtcgtattg ggggatgcat tcgggatacc agcaatcgca gtagataccc
     3121 acgtggaacg tgtctcaaaa cgcctgagga tctgcaaact agatgctacg gtcatggaag
     3181 tagaagaaac actgatgcgg aaagtaccac aagaattatg ggtaaagaca catcatacac
     3241 tgattttttt tggtagatat cattgcacgg caagaaatcc caagtgcgag gtatgtcctt
     3301 tgctatcaat atgtcaagat gggaaaaatc ggatgcgtct aaaagaaaag gcgctaaaaa
     3361 agaaaccacg cctgtagacg tggtttcttt aattgcaaat aaatgtatga attatcttgt
     3421 tattatggag aaaagctgtt tcgtttatct tttttgcatg aaaaagtaaa tgtacatact
     3481 cagtagctag gatggtaact tattacaatt tattgcgata aaaataaaag ttgttatttt
     3541 tattgggaaa atacccgatg tagaaaataa tgccttccaa tatacctata aaataagtcc
     3601 agtattccaa aggattatat aaataagtga cgtatctatc taaaggtgta ataaaaatga
     3661 taagtgataa taaaaaaata ccatttataa ctaaacataa actaatggat ttgggcggtt
     3721 tcaggctcat cagaaaaata tagattctgg tgaacaacaa ccataaaaaa gtgagaatca
     3781 ttgcatgaga gcttctttcc ataaattttc ctttaagagt agtgcttaaa agtacagaaa
     3841 aaataataaa tgcaaggata ggagcaatta aagtaaattt atttaataat aaacaaaatt
     3901 tttcagcttt tttattcttg gaataacgag gtattgtttt cgataaaaaa agatggtgca
     3961 gacaaattat gataattaag catactatca gataactcaa aatgaagcct tctttcaaaa
     4021 aattattcaa aaccatatat tgtatttttt atttgataat aacaatggga ttattaagaa
     4081 gtggcactaa ataaaagact agtgtgtatt tagccgattt aattataaac aagtaaatgg
     4141 ataaagtata tgtaatgata aaagaaaaat ggattttcta atttttaagc taaatgttag
     4201 atcacacatg tatatgctgg atagtcttat aaaaaatcat gtaatacagc ttggtacatg
     4261 atttttattt gtagctgttt tttacataga cacaaaaaag aaaccacgct tgtagacgtg
     4321 gtttcttttt tactatctgt ttccagaagc tgaggtgctg ctggatggtg tatggtcatt
     4381 tgcagcatcc gctccgctag ttgctggctc actggaagaa gcaggaggag cagatgaaga
     4441 cggtgtcgag ctttcttcgg atgaagaaga aggaaccgtt gttgaagacg ctggctcgct
     4501 tgtttctgct gtcgtgcttt cttttgagga ctcagcagtt gattcgcttt gactagtaga
     4561 gctagagctt tgagtcgttg tctctgttgt tgagcttcca ggagtctgga catagctgga
     4621 agatggaata gttgttgatg gtgtaattgc attcgatcta gctgtatatt gatctttgta
     4681 gtacagttca ccgcccacac gaattaatcc gcttggcatc tcccagtctg tatttgtcac
     4741 gttagctgaa acatactgca taagctcgcg ataaacatca gaggctacgt gtgacgattc
     4801 tgaagtgaca ggcgtcattt ttttattgta acctgtccac acggaaatcg aataatttgg
     4861 cgtatagccc gcaaatagga tatctggata caccccagaa gaaataccaa gttttgcata
     4921 ctcgtcatct gtgtaattgg atgttccggt cttaccggct tgatataacc cagcgatttg
     4981 cgcattcgta ccagttcctt cagtgatcgt atcttttaaa atgtctgtga tcatataagc
     5041 tgtttctgga gacatggctg tttttccatc tggctcataa gtttcttctg ttccgtcttg
     5101 gaagacgatt ttattaacat attgaggttt gtaataagtc cctccattgg cgaaagccgc
     5161 ataggctgct gccattttta aggaagaagc tccgtatttt gtcccatctt gttcttccgt
     5221 attactagag atcgcattcg attgatggat cgtactgtat tcgatcccaa gattttttaa
     5281 gaaagaagcc actttatctg aaccgacttc attgaataat ttgactgctg gaacattacg
     5341 ggataagtaa agtgcttggc gtaaagtaat ggtgcccata tattgattat cccagtttcc
     5401 tacaggagtc gaagtccctt catagttata cggtgcgtca gtaatagttt ttccagtaga
     5461 atatttcaaa tattcaaaag ctggtccgta atctgtgaca ggtttcatcg tagaaccaaa
     5521 atcacgggaa gtattcactg ctaagttgtt gcctaaagtt acgtcttctg cgatgtgacg
     5581 tccgccaatc tgggctttta ctttcccggt attggtgtcg ataagggtgg aggcaacttg
     5641 catctcgtcg tctgggtaag agacatactg atccgtgttg acgatatcat atagtttctt
     5701 ttgggcgtcc agatccaaat tcgtataaat ctctaaaccg tctgtgtaga cattcttatc
     5761 tgttttttct tgtacttcat tgatgacttc tttgacataa ttatcgacga tcttagtatt
     5821 gtcatcggat tgagttagtt cttgcagacc atccgttacc ggtacattaa cagcttgatc
     5881 atattctgtt tgagagattt tttcgttttg aagcatcgta tacaaaacag tatctcgtct
     5941 tttcttcgcc tgatctggat aaacataagg atcataggcg gaaggggctt gaggcatccc
     6001 agcaagcaat gctgtttgcg gtaaagaaag ttctgataat ttcttaccaa agtacatctc
     6061 agaagctgtc tccatcccgt acaagccgtt tgacatatac actttattta cgtagtaggt
     6121 caagatctct tgtttcgatt ttttttgttc caatcttaca gccatccacg cttcttgggc
     6181 cttgcgtttc agagtctgat cctcggcact ggtggagaag aaggaaagtt tgatcaattg
     6241 ctgtgtcaaa gtacttccgc cttgcagtcc gccagaggta aagttagaga gggcagaacc
     6301 gatgatccga atagggtcaa ccccgatgtg tttataaaaa cggcgatctt ctaccgacac
     6361 gatcgcatct tctaatgttt tcggtaattc attcgcagaa attttttcac gcttttctgc
     6421 gcctaaatct tcgaatagtt cgccatcttg tgtatatagt ttggaagata cggtagcgtc
     6481 taatttttta tccgtcaatt cgggcgcatc ttttgcgtaa taccagaaaa gtcctacacc
     6541 tgctaaaaag aggatacaga aaaatgagag tattcctaaa aggatcttga taaataatcc
     6601 ttttttatgt gttccagagg actttccaga acctttgcca gaattcttct tcacactctt
     6661 tttaggagta ggctgtttct gtcgtctaga gcttctagtt tgttcatttg ccattcttgc
     6721 tttctccttc aatagataat gttgataaat agaagtcaac cgcgtccaaa taaggaatcc
     6781 gcggagaaat accagttttg atctctattc ctagttcttc gatcaaagat aaaggtagtg
     6841 atttgcgtcc tttttccttt tgggcgtccc agtaagcaat caaatgaaca ctattcaaat
     6901 aaaaacagcg cttcaaagac gaaaaccata acaagacaaa gcagacccca ttttgttcga
     6961 ggcatgcttt catatgttcg atttgatggg catggaagtt tttaaaggga aaagatgttt
     7021 tgttcttggt ttcttttgct tcaaagtcca agtaaaagcc tcgatagacg ccattatagt
     7081 ctgtagttga ggcttgggta aagtaggctt ccttgatcac agcagcactt ctcttaggat
     7141 agtctacttt cacgatttgg ataggggtag gctttttatg gataaccgcc aacccgcggg
     7201 aaagataata tttattactt tcattgattg cttcttcaaa gcgcatcccc cgattgccga
     7261 attcagtgat ctgatttctt ttttcttgaa ttttttcgac gggagaggca ttcttataat
     7321 aaggttggcc atttggatag cgcaatacca tctttaatca cactcctagg ccacattata
     7381 gcaaaaaagc ggatagaaag aaaaggaatc tgagatggat aagtcaaaag taatctatgt
     7441 gtctgggtat cgaagtttcg aactcggtgt ttttaaagaa aatgatccta aaatccaagt
     7501 tgttaaaaat gttttaaaaa aagaactcca tcagttagca gaagaagggc tggaatgggt
     7561 acttgtcagt gggaatttgg gcgtcgaact atgggctgtg caaatagtag cggaattgaa
     7621 agaagaatat ccggaactat ctcttggtat tttgtatcct ttttctgatt ttggtaataa
     7681 ctggaatgaa gggaaccaag aaaaaaaaca attagcagaa caattagcag attatgtcga
     7741 agctgttagc catcaaccct accaatcacc tagtcagcta aagaatcaca ctcgttttat
     7801 acttgagcat acagtgggct gtctgctgat ctatgatgaa gaattccctg gaaaaacgaa
     7861 gtattttttt gaagatgcac agaattacca agcagatcat ccctacgaaa ttcggctgat
     7921 cagtatggac gatcttcaaa attttagtga ataatcgata ttgtgtttga tttatcaact
     7981 tttttcctat acaatgaaaa aggtagaaat gttattacgt aaatgaaaac tagaggtgta
     8041 aatatggcga atttggttta tagtcctaaa gacattttac aacaagaatt caaaacaaaa
     8101 atgcgcggct atgatcccgt tgaagttgat gaattcttag acaatatcat caaagattat
     8161 gaaacttaca gcaaagaact ccttgcttta caagaagaaa acgatcgatt gagtgcaaaa
     8221 gtagctcaat tatctaaaac tcaaggagca gctcaaacac gcgtgcaaca aacagaggca
     8281 ccaaagagcg cagcagtgac caattttgat atcttaaaac gcttgtcaaa tcttgaacgt
     8341 gaagtatttg gtaaaaagct tgatcaacaa gcaagtgcag tcaaaccagc acaacctaat
     8401 ccaaataact acacaaatgc agacacaagc ttagatgata atgaaaaaac acgtcaattt
     8461 taatttttga ttaatgaatt tgcggttttc gggtaatcgc ggtctgactt gatcaggctg
     8521 aggaaagtcc atgctcgcac aggctgtgat gcctgtagtg ttcgtgctta gcgaaaccat
     8581 aagctaaggt actctttgga gtaacggcag gaaaacaagc taaggcttcg gctatgctta
     8641 agtatccttg aaagtgccac agtgacgaag cggctgggga aacccatccg gtggaacgcg
     8701 gtaaacccct cgagcgagca acccaaacaa tggtaggggc gctttttgtc tggaagaaga
     8761 acaggacaaa aaggcagtat aactgcagat agatggttac cgctttgttt tttctccctg
     8821 gaaaagcaaa gtacagaaca tggcttatag aaaaccgcaa acatcaggga attaggtcgt
     8881 gacaaaagta atgcgttata agaaacaaga aaaacatttg aaagctattt ttcaatactt
     8941 cagatgaatc gttcttatta caaaacaaac ttttgtatca ccggttattc ggaatttgag
     9001 taaaagtgtg gggtaggact gatgtcccac ctcctttttt tataaataag gagattgtgt
     9061 atggaaaaaa acaggaagtt caacctcgtc gcaactgcgg caagcgggct agaagcactg
     9121 gttggtaaag aattaagaga tcttggaatc gaatgccaag ttgagaacgg acgtgcacgt
     9181 tttgaaggaa caatggaaac gatcgctaca gctaatttat ggttacgtac agcagatcga
     9241 gtaaaaatcg tggttgggga attcgatgcg tatacgtttg atgaattgtt tgaaaacgta
     9301 aaagcattgc cttgggaaga ttttcttcca ctagatgcag cttttcctgt agctggaaaa
     9361 tcgatcaagt cgaaactata tagcacacct gattgccaag cgatcacaaa aaaagcaatc
     9421 gttgaacgtc tccgtaccta ttatcaccgt ccagcttctg taccactgac ggaaactggc
     9481 gcacattttc agttggaagt agctttgctg aaagaccatg tgatggtaac tctggatacg
     9541 acaggaccaa gtttattcaa acgtggttat cgcttagaaa aaggtggagc accattgaaa
     9601 gaaaacatgg cagcagcact tattatgttg acaaattggc gaaaagaccg tccattttat
     9661 gatcctgtat gtggttcagg tacgctttgt attgaagcag ccttaatagg ccataatatc
     9721 gcaccaggat tcaatcgtga gtttgcttgc gaatcttggg attggttcag tcaagaaatc
     9781 atggaaaatg ttcgatcagc agccgaagaa aaagcagatt atgatattga attagatatt
     9841 actggttcag atatcaatgg acggatgatt gaaattgcca aagccaatgc agaagaaatc
     9901 ggattaggct cttcgattac ctttaagcaa caagcagtca aagacttcaa aacggataaa
     9961 gaatacgggg tcatcgtggc taatccgcct tacggagaac gtctaggaga agaagaaact
    10021 gttcggaaat tatataaaga aatgggcgat gtattccgtc cattaaaaac atggagtaaa
    10081 tatatcttga ctagcgactt agcgtttgag gaattttacg gacaaaaagc aaccaaaaaa
    10141 agaaaattgt acaatggtgc attgcgtacg gatctattcc agtattgggg aactcgtccg
    10201 cctagaaaaa aagagaaaga cgaataatct tactaattga ttcattcaat tggatgtttg
    10261 gaggaatagg gaatgaaaga aaaagagttt ttacaagaag taaaagaaat caatcttcta
    10321 caacaagctt taggaatcct cgattgggat acacaaacag gtatgcctga aaaagctagt
    10381 gcataccgaa gtgaagtaga cagctatctt tacagcattt atttttcaaa aaaaatcggt
    10441 ccaaaaatca aagaagccat tcgctatttt tctgaacatc cggaagaatt gtcggaagtt
    10501 ggaactgccg tttttgccaa agtaaaagaa gagtatgatt tggaacatcg cgtaccggaa
    10561 gatcttatga gaaaatatac agctgccgtt tcttcagcac acggacaatg gcaaaaagct
    10621 agagaaacac aacaattttc tgattttcaa cacgcattga atcaaaatat tgaattaaca
    10681 aaacagttga taccttactg gagaaaagat gaaaagacga attatgatgt tttgctgaat
    10741 caatacgaac ccgggatgac tgtcgaaatc cttgataagg tatttgatca gcttaaagaa
    10801 ggaattcttt cgatccgccg tacgctccaa gaaaaaggga ctgaacctga aacagacttt
    10861 ttaaatcgga gaatgacgaa aaaacaacag aagagatttg tagtgaaagt aatcgaacaa
    10921 cttggttatg attttagtcg tggtcgttta gatgacactg tccacccatt tatgactgga
    10981 attaatccga atgatgcacg aatcacgaca cgatggaacg aaacagattt caaaatggct
    11041 gtttttggag tgatccacga ggctggtcat ggtatgtatg aacaagacat cgatgataaa
    11101 tatgcgtata caccggttta tgaaggtaca tcaatgggta tccatgaatc acaatcgttg
    11161 tttaacgaga tcattattgg aagtagtcgc agcttctgga aaaagcaata tcctttcttt
    11221 caagaatgtg cagaaggaac attcgatgat attccttttg acaaatttta tcgttcattg
    11281 aaccatacaa aatcaagttt ggttcgtatc gaggcagaca gtttgactta ccctctccat
    11341 atcatcattc gttatgaaat cgaaaaaatg attttcaatg aaggggtaga tgttgctgaa
    11401 ctacctgaaa tatggaatca aaaatatgaa gagtatctgg gaatacgacc aacaaatgat
    11461 gtggaaggca tcctacaaga cgttcattgg tcaggtgcaa gctttggtta ttttccctct
    11521 tatgcattag ggtacatgta tgcggcacaa ttacttcatt ctttgcagca agaaatagat
    11581 gtggaaaatg ttctagcgtc agacgattat tctccaatca aaaactggat gtcagagcat
    11641 atccatcaat atggtgcatc tagaaaacca aatcaattaa tcatggatgc aacacatgaa
    11701 ccgcttaatc cgcaatacct gatcgactat atgaaagacc tgtattttaa tgtatatcag
    11761 gtaaaataaa atacaattta caaagatagc tgaaattcat ctaatctata gatgttttca
    11821 gctatttact taagaaagaa gtggaacgaa tggataaatt acaagtgatc gctgattata
    11881 gtatggacca attagcgcat gatcaaacag gacatgggag cgatcatacc aaaagagttg
    11941 tcaagttagc tgaaaaaatt ttggagacgg aaccgcaggc agaccgcttt gtgacgcttg
    12001 cagcagctta cctacatgat acgattgatg ataaagtcgt taaaaatgag aacgaggcaa
    12061 agcaacagct tcgtgtattc cttcgctctt tgccaatagt agaggaacag atctcgatga
    12121 ttttttccat tatcgaaaat atgtcctttt ctaaaaatct ctctgaagcg gccgaactat
    12181 ctctggaagg taagatcgtt caagacgctg atcgtatcga agcattagga gcaatcggca
    12241 ttttgcgtac tgcttatttc ggcggtggac atgggcaccc gatttttgat cctgaactgt
    12301 atccgcaaac attcaaggac aaagaaaatt accgaaaagg cacgacagtg atcaatcatt
    12361 tttatgaaaa actgttcttg ctgtctgata aaatgaatac tgattacgga tatgaagaag
    12421 ccaaacgaag agaaaccttc atgcgtgaat tcttagaaga attttttctg gaatggtcta
    12481 ttgacgatga aaattttact ccagacaatt ggatcaaaaa taacaaaaaa tgatggaggt
    12541 tgtgacagaa gtggtcagct ccaagatatt tcggatcatt ttccgtaaaa gttacttctg
    12601 gaacactgtt taccaagagg tcgtgagcct gccgttcagc tccgagtcac aaggaacaat
    12661 ttcaaaaaat agcttctcgt gtttgatgaa tattgtaact tgtgattcgg aattggcagg
    12721 agaacaccgt ttatt
//
LOCUS       DACCVZ010000080        12734 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.083, whole genome shotgun sequence.
ACCESSION   DACCVZ010000080 DACCVZ010000000
VERSION     DACCVZ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.083"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="IVW63_002248"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="IVW63_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAP7860510.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="IVW63_002249"
     CDS             complement(323..892)
                     /locus_tag="IVW63_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAP7860511.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="IVW63_002250"
     CDS             1078..1980
                     /locus_tag="IVW63_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP7860512.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="IVW63_002251"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="IVW63_002251"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAP7860513.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="IVW63_002252"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="IVW63_002252"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAP7860514.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="IVW63_002253"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="IVW63_002253"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAP7860515.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="IVW63_002254"
     CDS             8548..8733
                     /locus_tag="IVW63_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HAP7860516.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="IVW63_002255"
     CDS             complement(8795..9991)
                     /locus_tag="IVW63_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP7860517.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="IVW63_002256"
     CDS             complement(10161..11597)
                     /locus_tag="IVW63_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP7860518.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="IVW63_002257"
     CDS             11890..12699
                     /locus_tag="IVW63_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7860519.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3801 a         2673 c         2250 g         4010 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgac
//
LOCUS       DACCVZ010000081        12494 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.084, whole genome shotgun sequence.
ACCESSION   DACCVZ010000081 DACCVZ010000000
VERSION     DACCVZ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.084"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            158..730
                     /locus_tag="IVW63_002258"
     CDS             158..730
                     /locus_tag="IVW63_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAP7860520.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            962..1579
                     /locus_tag="IVW63_002259"
     CDS             962..1579
                     /locus_tag="IVW63_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006845390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP7860521.1"
                     /translation="MNYIAEKAHTKQYQKGEFLFRSQEKEDTLYIINRGKIRIYRLAD
                     SGKEQLVRILNPGDFTGEWTLFNSDAVHEEYAEATRDTVVCMIQQKDVQDFLEQYPAI
                     SLKLLAEMSKRLESSERQTTQVAVESVITRLVLFLAENVEPEMGNSPTITLPMAKKDI
                     ASYLGTTPETISRKFGELEDEGLIQQLSGKRIKIQDLDDLLLYSE"
     gene            1807..2145
                     /locus_tag="IVW63_002260"
     CDS             1807..2145
                     /locus_tag="IVW63_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860522.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2130..2984
                     /locus_tag="IVW63_002261"
     CDS             2130..2984
                     /locus_tag="IVW63_002261"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003125438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAP7860523.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            3131..3364
                     /locus_tag="IVW63_002262"
     CDS             3131..3364
                     /locus_tag="IVW63_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HAP7860524.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3562..5466
                     /locus_tag="IVW63_002263"
     CDS             3562..5466
                     /locus_tag="IVW63_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAP7860525.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISIGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPAEKVKIS"
     gene            5776..6138
                     /locus_tag="IVW63_002264"
     CDS             5776..6138
                     /locus_tag="IVW63_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7860526.1"
                     /translation="MEKVCQVTIVHKEKVNVIKKKLDQKDFSNLLVLGKCFSDSSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVFLKLSENLSMKS"
     gene            6155..6766
                     /locus_tag="IVW63_002265"
     CDS             6155..6766
                     /locus_tag="IVW63_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HAP7860527.1"
                     /translation="MLQSIFSAIAVYISTSIDYLFILLIIFSQSHTKKGIRHIFWGQY
                     LGTGILVAVSLFAAYVLNFIPQDWIIGLLGLIPIFLGIRVAFVGEEEEEEEEVVEKLE
                     SRGTNRLFWTVALITIASGGDNLGIYIPYFTSLAFSEIIIALIVFAISVAVLCYISYK
                     LAKISFVSETLEKYERIIVPIMFIALGIFIMIENGTIQTLLGF"
     gene            complement(6868..7776)
                     /locus_tag="IVW63_002266"
     CDS             complement(6868..7776)
                     /locus_tag="IVW63_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAP7860528.1"
                     /translation="MSKSDKDHNHSNQNQPKKNIKIAFFINLIFSISEFFFGFLFNSV
                     SIMSDAVHDLGDSISIGFAWFFQGYSEKKQDERFTFGYNRFSLLGALITGVVLISGSF
                     FMIYRSVPRLIDPQPVNYSGMFWLSLVAIALNGYAAWILSKGTSKNESMLNLHMLEDV
                     LGWIGVLIVSILMNFTEAYRLDPILSILIALYILYKTVPEFFTTMKILLNGSPENVNV
                     KSLADSIKNVPAVKDLSHFHIWSLDGEENALIITVLIDPSDIDKAREIKEEIAEVAHK
                     SSVENHITIEITTSKEELEKGYSHNT"
     gene            complement(7818..8132)
                     /locus_tag="IVW63_002267"
     CDS             complement(7818..8132)
                     /locus_tag="IVW63_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAP7860529.1"
                     /translation="MDIKTTSPIDKGSILSISKLFKVISDPTRLSVLFLLQKKECSVG
                     NIAISLDMEQSAISHQLKTLKDARLVKSRREGKSMLYSLDDLHVFSILEQVLTHVNEL
                     EK"
     gene            8431..10362
                     /locus_tag="IVW63_002268"
     CDS             8431..10362
                     /locus_tag="IVW63_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAP7860530.1"
                     /translation="METIQEQQSQEKHNHNHNHDHDHDHGKMPVVLYFVGLALAVIAL
                     FLNEDYQLVQNVLFSIATISAGYHVILLEGLGETIENSKAQKKFIPNSHILMGLAAIG
                     ASLMGNFWEGTLLILIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLILPDGSTKNV
                     DVSELKVGDQLQVLNGDQVPIDGVILSGSTSIDESSITGESIPKEKSKGDGVFGSTIN
                     GTGTFTMKVTKENKDTVFSKILQLVNQNQDNQTKAASIIQKFEPKYVTVVLIAIPLFM
                     LLAPFLLDWTWSQSVYRGLVLLVAASPCALAAATVSATLSTTSNLAKKGVLSKGSSYL
                     SQLADIKAIAFDKTGTLTKGKPEVTNYYFADSVNEENMIDIVVALEKESNHPLADAIL
                     RKFEQKNKLTIEVENQIGKGLTGDYKGRNYRIGKPTSFDDVSDEYSRLNNEWASEGKT
                     VVYVAVDEEVIGLIALMDVPSEYAKETIEYFRKQGIHTTLITGDSEMTGKAVAKQLGI
                     DEVIANVMPEDKSRIIDEQKEKYGVTAMVGDGVNDAPALVNADVGIAMGDGTDVAVEV
                     SDLVLMQNNLSKLVQSHNISSKMNRVIWQNIIFSMAVVAFLIVVSFLGLTDIAISVII
                     HEGSTLVVILNGLRLLKAV"
     gene            10655..11206
                     /locus_tag="IVW63_002269"
     CDS             10655..11206
                     /locus_tag="IVW63_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP7860531.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            11519..12061
                     /locus_tag="IVW63_002270"
     CDS             11519..12061
                     /locus_tag="IVW63_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860532.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
BASE COUNT         4048 a         2092 c         2609 g         3745 t
ORIGIN      
        1 aatttaatag agaagcctgg cgtctattaa gaaataattt tcttgatgag cgtcaatttt
       61 tttaacggaa atctatccta tactaaattc agtaaagaaa aaggaggaat caaagaaagc
      121 tattttaaac aaaccaaaat tataggagga ataaatcatg actgaaaata aagctactca
      181 agaaagaaca ccccaagaaa gattgcaaga agaacaagaa cacaaggaac atgttcatca
      241 tacgaaaatt aatgcagcgg ccattgcgga tcatctttta ggcaacatgc atacattaca
      301 tgtgaaactg caccaatatc actggtatgt aaaaggagcc aatttcttta cgttgcatga
      361 aaaatttgaa gagttgtata acgaaaatga aaaatggttc gacaaacttg cggagcgtct
      421 aattacttct gggcataaac ctgcttcgac aacggttgaa tttgaaaaat attcgatgct
      481 ttcggaagat gcagttaata aatacgctaa agcagaagac atggttgaaa atattatcga
      541 ggacttcaga agcactcgtg acctaactat tcgcgcgatt cgtttagctc aagacgaggg
      601 tgacgatgct ttagaagata cattgattgc ttttaaaaat gacttagaca agaacatttg
      661 gatgctgcaa gcgttcattg gtaaagaagc attagaagat gatgacgctc ttgatgagga
      721 tgaagattaa ggtaaaagta gaagctgatt tagggattgg aattctttcc agtccttttt
      781 ccattttctt gatgtgcatc aatttttttg tagtaagaga cttatataat aaaagcagcg
      841 aatataaaca aaataaataa agggggagaa tgaattgact aaacataccc atcatgaaat
      901 tggcgaccac gcagcctgta tccgcttggt tccaatattc aatcacttag aggatagcgc
      961 gatgaattac attgctgaaa aagcccacac gaaacagtat caaaaaggag agtttctgtt
     1021 tcgttcacaa gaaaaagagg atactttata tattatcaat cgtgggaaaa tccgtattta
     1081 tcgattggca gactctggca aagagcagct agtgcggatc ttgaaccctg gtgatttcac
     1141 cggagaatgg accttgttca actcggatgc agtacacgag gaatatgccg aagcaacccg
     1201 agataccgtt gtctgtatga ttcagcaaaa agatgtccaa gattttctgg aacaataccc
     1261 agctatttct ttaaaactat tggcggaaat gtctaaacgg ttagaaagtt cagaacgtca
     1321 aacgacacaa gtagccgtgg agagtgtcat tacccgttta gttttgtttt tggcagaaaa
     1381 tgtggaacct gaaatgggca actctcccac catcaccctg ccgatggcaa aaaaggacat
     1441 tgcttcctat ttaggaacga cacctgagac catcagtcgc aaatttggag aattggagga
     1501 cgaaggattg attcaacagc tgtctgggaa aaggatcaag attcaggatt tagatgattt
     1561 attgctttac agcgaataat cggacacact tttttctaca cgttggtgtt ctgtcgctct
     1621 tcattaacaa cgggacagaa ctcagtgctt ttgcttccat ctgtccgttt ttggcttttt
     1681 taagacagaa cgaccttcat tcattggaaa aataaaagca caaacatgat aaccctcaag
     1741 tttttttgtt ttatttttct ttaagatagg gttgtcgaac aaaacgtaaa aataagtagg
     1801 gtgaatgtgc attgtttttg ggtgatagtt gccatcacgt tgtcagcagc gggggcattc
     1861 tttgtcgtcc ctttcaccaa gaacacgatt ggcggcgaag caaaaacgtc taacgttgtt
     1921 gaggcagata ggttagctat ggaaaaagaa gaggaagttg taaaaggagc cggcgtaatc
     1981 ggacacggaa aagtggcgta ttacgaagcg agtgaccagg gagataaaag tgtattcact
     2041 gtttggtttc catggagctt agccggaatc ttgttcagca tcaccatgac tagaatgacg
     2101 cgaaaaattg aagaaatgga gcaaatagaa tgggattcgt attaggcgtt ttgaatcccc
     2161 atgtggtgga gattggttct gttgtgattc attggtatgg agtcattatt gcagcgggca
     2221 tattagcggc tctccagttg agcaccaagg aagcaaagaa aaaaggactg gaagaggata
     2281 ccattatcga tatggcctta tgggcaattc cgattggact cctcggcgct cggctttatt
     2341 atgtgttatt tgaacttggt tattatctgc aaaatccagg acaaatcctt gcgatttgga
     2401 atggcggcat tgcgatttat gggggattga ttgcaggagg gggtacgcta tattggtatg
     2461 caaagaaaaa aggtacttct ttggcactcg ttcttgatat tttagcgccc aatgtattgt
     2521 tagcccagtc cattggtcgt tggggcaatt ttatgaatca ggaagctcat ggtgggccgg
     2581 ttactcgtca attcttggaa aatctttatt tacctgaatt tatcattgaa caaatgaata
     2641 tgaatggtac ctactaccat ccgacttttt tatacgagtc attgtggagt ttgttgggct
     2701 ttgtcctcat cgtcactata cggaaccgaa aacagctttt gcgtcaagga gaagtcgctt
     2761 tgagttacgt tttgtggtac tcagtgggtc ggttcttcat tgaaggtatg cgaacggaca
     2821 gtttatggat tggcgagtgg atccgcgttt cgcaagcctt gtctctggcc ctgtttattg
     2881 gcgcgattgt agtatggttt atacgcagac aagattatcc accaatttct tattattctg
     2941 atggcaataa ggggcagaaa aagactatta agatggtgaa ttgagcaaaa agataaaaag
     3001 aagtgcaaaa cttgatatgc gtcaattttc gtttgctaaa agtgagctat actacagttg
     3061 taaagaggaa aaggcagtgt tcattaatct gctgccgata aaataaaaac acataaagga
     3121 gataggaatt atggaaaaag ctatattgca attagaaacg ttgtcttgtc caagttgtat
     3181 gcaaaaaatt gaaggtgccg tgaaatcagt taacggtatt gataaagaca gcattaaagt
     3241 attattcaac tccagcaaag tcaaaaccaa ttttgattca gctgtcactt cgattgaaga
     3301 gattcaaaaa gctatcgaaa acgtaggcta tccggttctt aaagcaaaag tcaaggccgt
     3361 ttaacagatt aaatgaacta ggcaattctg gaagaaaagc tatttttcca ggattgcttt
     3421 ttttgttgca atccgattcg aggtgcttag aaacgataaa agagaacttt ctaaacttga
     3481 tgtcagtcaa ttaattactt aggcaattat cttatactgt gtttatcaat aaaagagaaa
     3541 ttaaatttgg agggaaaaag catgcaacaa tatatattaa gcaagaaaaa tgttatcacc
     3601 gtcatcagtg gattgttaat cgtactcggt ttcttcagtc actttgtttt agaaaacgta
     3661 ggactttcag agtggtcttt gatcatcgcc tctgtctttg ggattacgcc aattgccatt
     3721 caagcgtttc aagcaatgaa agtcaaagtc atcagtattg atgtcttagt cagtattgca
     3781 gcgattggtg cgctttttat tcaaaattat gaagaatcgg ctattgtcac gttcttattc
     3841 ttattcggac actacttgga acaacgaaca ttgaaccaaa cgcgatctgc tatcaaagaa
     3901 ttgactgaaa tggcacccga aagcgccttg aaacaaatgg ataatggcga atttgaagaa
     3961 gtagaagtgg atgatataga tgaaggggat atcttgctcg ttaaaacggg tgcgaaagtt
     4021 ccagtagatg gcatagtcct tacgggtgaa gggcatatca atgaagctag cattacaggt
     4081 gaagctattc cggtcaacaa gctagctgat gcagaagttt ttgcaggaac cattttagaa
     4141 aacggaacga ttcaaatcag agctgaccga gttggtgagg acaccacatt tggaaaaatt
     4201 attgaactcg tggaagaagc acaagattct aaatccgaag cggaacggtt cattgatcgc
     4261 ttttctaaat actacacacc agctgtcttg gttctggcaa ttgttgtatg ggcgttcagt
     4321 caaaatattg agttagcaat caccatcttg gttctaggtt gcccaggcgc attagttatc
     4381 ggagtgcctg tctcaaacgt tgccggtatt gggaatggtg ctcgtaacgg tgttctttta
     4441 aaagggagtg aagtcattca agacttcagt aatgtggata caattgtatt tgataagaca
     4501 ggtactttaa ctgtcggaaa cccaaccgtt gcagcgactg aactgtatga aaaagatcct
     4561 gctgaaacgc ttggctatct ggccagtgtg gaacgggaat cagatcatcc attagcaaaa
     4621 gcggtcttaa atcaaattgg agaaacaaac ttttatcctg ttgaaggaac tgaagttgtg
     4681 aaaggcggcg gaatcgtttc aagtgtagct ggacatagag tggctgttgg gaatgtggcc
     4741 ttgatggaaa aagaaaatgt cactctcagc aaaaaagtgc aaaaagatgt caaacggttt
     4801 gaacaacaag ggaactctct cgttttgaca gcggtcgacg gtgaattaaa agtactgatg
     4861 ggcattcgcg atcaagtccg tccgggtgtg aaagctaatt tgcaggaatt aaaagacttg
     4921 ggcgtgaaaa atctagtcgt tctttcagga gataaccaag gaaccgttga tgtggtcgcc
     4981 ggcgaacttg gtttgaccga agctcacggc tacatgttgc cggaagacaa atcggcttat
     5041 atcggaaaac ttcaacaacg tggtcaaatt gtagcctttg ttggagatgg cgttaacgat
     5101 agtccgtcct tagctttagc agacattgga atcgcaatgg gaagcggaac ggacgtagcg
     5161 attgaaacat ccgatgtcgt tttaatgaac tcgaacttca gcaacttgcc tcacgcatta
     5221 ggattagtaa aagccaccgc aaataatatg aaacaaaata tcgtgatttc aattggagta
     5281 gtgttggtct tgttgaccag cgtcttcttc agcgaatgga tgaatatgtc tatcggaatg
     5341 ttggttcatg aaggtagtat cttggtggta attttcaatg gcatgagatt aatgaagtat
     5401 aagttgaaag gtcgaaaaga acaaaaagaa gtatcagcac ctgcagagaa agtaaaaata
     5461 tcttaagaat aaattagaag aggctgagac aatagtccat ccttgaaatg acaaaagcgg
     5521 aaactcagat ttttaaatct gggattttcc gcttttttga gttcttgaaa aaaaataaga
     5581 gtatagagta tgttctttat aaaattaatt ttcgtgtaaa tgattaaaaa atttaataat
     5641 aaaatttaaa ttcctattaa gttgtaacac atgaaattgc ttataatagt gtattgaaat
     5701 taaggtagat tgacaaacga gtgatcaaat agatatacta ccttcaaacg accgtttgaa
     5761 tgtgaggtga gatgaatgga aaaagtttgc caagtgacta tcgtacataa agaaaaagta
     5821 aatgtaataa aaaaaaaatt ggatcaaaaa gatttttcaa acttacttgt gttagggaaa
     5881 tgtttcagcg attcttctag gattaaaatt ttctatgctt tagaaaccta taaggaaatg
     5941 tgtgtctgtg atttagcaga aatacttact gctagtgtcg ctacaacgtc acaccattta
     6001 cgttttttaa aaaaacatgg aatggcaaaa tcacgtcaag atggaaaagt agtttattat
     6061 tctttagcga atgaagacat cctttccgct attcgtgttt ttttaaagtt atcagaaaat
     6121 ctatctatga aatcttagtt tggaggaagt tattttgtta caaagtattt tttcagctat
     6181 cgctgtttat atttctacca gtattgatta tttgtttatc ttgctgatta tcttttctca
     6241 aagccacaca aaaaaaggta ttcgtcacat tttttggggt caatatcttg gaacaggtat
     6301 tttggtagcc gtaagtttgt ttgctgctta tgtgctaaat tttattccgc aagattggat
     6361 cattggtctt ctcggtctaa ttccgatttt cttaggaatc agagtcgctt ttgttggcga
     6421 agaggaggaa gaagaagagg aagtcgttga aaaactcgaa tctagaggaa ctaatcgctt
     6481 attctggaca gttgccttaa taacgattgc ttctggaggc gataatttag gtatttatat
     6541 tccatacttt acctcgttag ctttttcaga aatcattatt gctttaatcg tattcgctat
     6601 ctctgttgcg gttctctgct atatcagtta caaattagcc aagatttctt ttgtttccga
     6661 aacgttagaa aaatacgaac gaatcattgt ccctataatg tttattgcgt taggaatttt
     6721 tattatgata gagaacggga cgatacaaac gctactaggt ttttaaaaat cataatcacg
     6781 aaagataaaa agagaggcag cgactaatca aaatcgctgc cttttttgct tttcaaataa
     6841 tgaagtattt tttagcgtag aactatctta cgtgttgtgg gagtatccct tttcaagctc
     6901 ttctttgctt gtagttattt ctattgtgat atgattctct acgcttgatt tgtgtgcgac
     6961 ttctgcaatt tcttctttta tttccctagc cttgtctatg tctgaagggt ctataagaac
     7021 cgtgatgata agggcgtttt cttccccgtc cagtgaccaa atgtgaaaat gtgagaggtc
     7081 ttttacagca ggaacatttt taatggagtc cgccaagctc tttacgttta cattttcagg
     7141 cgaaccattc aataaaattt tcattgtggt gaaaaattca ggaacggttt tgtagaggat
     7201 ataaagtgca atcaaaatcg ataagatagg atccagacga tatgcctcgg taaagttcat
     7261 tagaatactc acaatcaaga ctccaatcca ccctaatacg tcttccagca tatggaggtt
     7321 caacatgctc tcgtttttgg atgtgccttt gcttaaaatc cacgcagcat atccattcaa
     7381 tgcaatagct acgagagaaa gccagaacat gccactataa tttacgggtt gtgggtcaat
     7441 caaacgtggc acactacgat agatcataaa aaacgagcca ctaattagca caacgccagt
     7501 tatcagcgcg cccagtaaag aaaagcggtt atagccaaaa gtgaaccgtt catcttgttt
     7561 tttctctgaa taaccttgaa aaaaccaagc gaatccaatt gaaatagagt cccctaaatc
     7621 atgaactgcg tcggacataa tggacacact attgaaaaga aagccaaaga aaaattcgct
     7681 tatagagaaa ataagattta tgaagaaagc aattttaata ttctttttcg gttgattctg
     7741 attcgagtga ttatggtctt tatctgattt tgacatttaa aaacctccta agtttgtatg
     7801 ctacatacta attggtttta tttttctaat tcattaacat gagttaagac ttgttcgaga
     7861 atactaaaaa catgaaggtc atctaaactg taaagcatac tttttccttc tcttcttgat
     7921 ttcactaagc gtgcgtcttt caacgttttt aattgatgag aaatagcgga ctgttccatg
     7981 tccagagaaa tagcgatatt tccaacacta cactcttttt tctgtaaaag aaagagaacc
     8041 gacaatcgtg taggatcact aatcacctta aatagtttgc ttattgacag aatagatcct
     8101 ttatcgattg gagaagttgt ttttatatcc atagtgtttt tattcctttc atatgacctt
     8161 ccgttcatat ctatattacc atatgagcga aacaatgcta atcttttgtt tataaaagag
     8221 aagtggcgtt ctctttatct tgacaaaatg tatatagcga tataaaatga gtatacaaac
     8281 atatgattaa ttagtcatat gtaaggtgga ttcattacga tttacttttg gaataaacga
     8341 aaggagtcag aaatagcaga aatttatgtg attcaagaag taaatgatgg aaaacaaagg
     8401 aattataaat tatataggga ggcaatagaa gtggaaacta tccaagaaca acagtctcaa
     8461 gaaaagcata atcataatca caaccacgat cacgaccatg atcatgggaa aatgccagtc
     8521 gttttgtact ttgttggttt agcattagca gtgattgctc tatttttgaa tgaagattat
     8581 cagttggtac aaaatgtttt gttctcaatc gctacaatca gtgccgggta tcacgttatt
     8641 cttcttgaag gccttggaga aacaattgag aattcaaaag cacaaaaaaa gttcatacct
     8701 aattctcata ttttaatggg attagcggca attggagctt ctttgatggg gaatttttgg
     8761 gaaggaacat tattgattct tattttttct ggcgcacatt ttttggaaga ttatgcagaa
     8821 ggaagaagca aacgagaaat aacgaaatta ctcgaaatga atccaacgac tgcccggtta
     8881 atcctgcctg atggtagtac aaaaaatgtg gatgtcagtg aattaaaagt gggagatcaa
     8941 cttcaagtgt tgaatggcga tcaagtacct attgatggcg tcattttgtc tggatctaca
     9001 tccattgatg agtcgtctat tactggagaa agtatcccga aagagaaatc caaaggagat
     9061 ggcgtcttcg ggagtacaat caatggaaca ggtaccttca cgatgaaagt caccaaagaa
     9121 aacaaagata cagtattttc aaaaatttta caattagtga atcagaacca agataaccaa
     9181 acaaaagctg cgagtattat ccaaaaattt gaaccgaaat atgtcacagt tgttttaatt
     9241 gccattcctc tattcatgtt attggctcct tttctacttg attggacatg gtcacaaagt
     9301 gtctatagag gattggtcct tttagttgca gcttcaccgt gtgctttagc agcagctact
     9361 gtctcggcaa cgctatcgac gacttctaat ttagccaaaa aaggagtcct ttcaaaaggt
     9421 agttcttacc tgtctcaatt agccgatatt aaagcaattg catttgataa gacgggcacc
     9481 ttgaccaaag gaaaacctga agtaaccaat tattattttg ctgattccgt gaacgaagaa
     9541 aacatgattg atatcgtagt agctcttgaa aaagaatcca atcacccctt agcagatgct
     9601 attctaagaa agtttgagca aaaaaacaaa ctaactattg aagtagaaaa ccaaattggt
     9661 aaaggattga cgggagatta caaagggaga aattatcgta taggaaaacc gacttcgttt
     9721 gatgatgttt cagatgaata tagtcgttta aataatgaat gggcgtcaga aggtaagaca
     9781 gtcgtatacg tagcagtaga tgaagaggtt ataggcctta ttgcccttat ggacgttccg
     9841 agtgaatatg ctaaagaaac cattgaatat tttaggaaac aaggtataca caccacatta
     9901 attactggtg actcagaaat gacgggaaaa gcggttgcta aacaattagg aatagatgaa
     9961 gtgattgcga atgtcatgcc ggaagacaaa tccagaatta tagacgaaca aaaagaaaaa
    10021 tacggcgtga ccgccatggt tggagacggt gtaaatgatg ctcctgctct tgttaatgca
    10081 gatgtgggaa tcgctatggg agatgggact gatgtggcag tagaggtatc tgatttagtt
    10141 ttaatgcaaa acaatttatc taaattggta caatctcata atatttcttc gaaaatgaac
    10201 cgtgttattt ggcagaatat tattttttca atggccgttg ttgctttttt aattgtcgtt
    10261 agtttcttag gcttaacgga tattgcaatc agtgtcatta ttcatgaagg aagtactttg
    10321 gttgttattt tgaatggact tcgattgcta aaggcagtct aaagaatgat tgcacaactt
    10381 caaattaatc gagtaataga gataattaag gattacacta cattttttat ctctattact
    10441 tgtttatatt tatctagatg ttcaaagtca aaatgatata tcaaccatac tcttgtggcg
    10501 cgggttgaat ataagataca tgaaattgga taaaatcatg tatcaagaat cctatcctta
    10561 tagggttctt tttttttact ccccctaaac acacgatttc gtgttgtaat aactataatc
    10621 atgtattcga acagactaaa aaggagggat tgtcatgggc tataatgttc agccactacg
    10681 gtcgcaacag gagattaatg attttttatt ttgcctgcga cggaataaaa atgcggaacg
    10741 tgacgttttc ttgtttctaa ttggaattaa cagcggtctg cgcatgtccg acatcgttaa
    10801 actcaagaaa aaagacgtga ttacctcaaa aaacccgcgc atcgtggagc aaaagacagg
    10861 gaaaacacgc attttatact taagcagctt acaggacttg attcacggct ataccgcacc
    10921 cttagatccg gaggcttact tgtttcccag tactaagggc ggccatttag aagtcaatac
    10981 ggtctaccag atgtttcaaa aggtcgcgaa gctgttagga agggacgata tcggcaccca
    11041 caccctacga aaaacctttg gttaccacta ttacaagaaa accaaagacg tggccacctt
    11101 aatggaaatc tttggtcaca gcagcgagaa gattaccaaa cgctacatcg gaattaatga
    11161 agatgaaatc agtgaaacgt tattaaattt tcggttaggt ttttgattgt attatataat
    11221 agataagcac agtaagacgg ttataatcac ccacagtatt ggacaaatca accttttttt
    11281 ggtatattat atatacaaat gagagcaggc tcatagtcaa cttgatataa atccggaaca
    11341 taagggtccg gcgggtggcg agcaccaaaa ctaaactcga tacaaatccg gaacgtaagg
    11401 gtccggcggg tggcaagcac caaaactaaa cctgtacaaa aggctgctct tttgagcagc
    11461 tttttttatt gggaaaaagg agcattcttc gcacgcggca aaaaaagaat acaaacgcat
    11521 gtctataaaa gagacaaccc aaattaccag acagttaaac gcgatttata aggctgctca
    11581 tctcttacaa gaacattttg tagataaaaa agtatccttt gtcggagaag tctcaacggt
    11641 agcgattatt ttttcgacaa ctaattttat gcacctctgt ggcattgatt atcgcagagg
    11701 cacacacttg ttttttcaag atgccttaga caggaaaata aatttacagg atattcaaat
    11761 caaaacggat gggacgacct ttcagaaatt acaagtaata ggtagccttg atttattatt
    11821 ggggaagcat atttctattg ttggcagagg tgtttactct tctcttcgct atgatgcagc
    11881 tattcgaaca aggaaaaaaa tattggctct gtctttgaaa caaaacggat taatctatat
    11941 ccctatctct ttgttaaacc tatcatcaaa ggaaattgga cctggacaaa aagttactgg
    12001 catttttagc gaggatttaa catccgggga acttaaaatg attatggaag tcatcgatta
    12061 atcattaata gtgatatgcg acgtcatttt gaagtaatta ttctattttg ggttataaaa
    12121 taaagcattt taagacgatt tcaaatcatt catgtgggtt atttatcacg gatgagcttg
    12181 aaatcgtctt ttatacgtat caaattgaaa tgttcggcat acaacctatc gttgttacta
    12241 cattactaat tgtcacttgt taaggaactt ggatcctttc taaacattcc ctagagataa
    12301 attttacttt atccctccgt taatatccaa tttaagcacc tttccgattc agggttaatt
    12361 tgcatatcaa gtgcagcttg tgttctagta agattagccc ttttagtccg gctgagttga
    12421 cttatggata taagatatgg tcatagcaaa tagatactac gtatagtctg ttaatttagt
    12481 gtcattaatc ttaa
//
LOCUS       DACCVZ010000082        12483 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.085, whole genome shotgun sequence.
ACCESSION   DACCVZ010000082 DACCVZ010000000
VERSION     DACCVZ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.085"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..185)
                     /locus_tag="IVW63_002271"
     CDS             complement(<1..185)
                     /locus_tag="IVW63_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860533.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPG"
     gene            complement(195..1010)
                     /locus_tag="IVW63_002272"
     CDS             complement(195..1010)
                     /locus_tag="IVW63_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7860534.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDSEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1272..1715)
                     /locus_tag="IVW63_002273"
     CDS             complement(1272..1715)
                     /locus_tag="IVW63_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HAP7860535.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1849..2187)
                     /locus_tag="IVW63_002274"
     CDS             complement(1849..2187)
                     /locus_tag="IVW63_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP7860536.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2175..2552)
                     /locus_tag="IVW63_002275"
     CDS             complement(2175..2552)
                     /locus_tag="IVW63_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP7860537.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2776..3969
                     /locus_tag="IVW63_002276"
     CDS             2776..3969
                     /locus_tag="IVW63_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7860538.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4135..4557)
                     /locus_tag="IVW63_002277"
     CDS             complement(4135..4557)
                     /locus_tag="IVW63_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP7860539.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4952..5146
                     /locus_tag="IVW63_002278"
     CDS             4952..5146
                     /locus_tag="IVW63_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860540.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5143..5637
                     /locus_tag="IVW63_002279"
     CDS             5143..5637
                     /locus_tag="IVW63_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860541.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(5799..6971)
                     /locus_tag="IVW63_002280"
     CDS             complement(5799..6971)
                     /locus_tag="IVW63_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP7860542.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7177..7992)
                     /locus_tag="IVW63_002281"
     CDS             complement(7177..7992)
                     /locus_tag="IVW63_002281"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP7860543.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNMI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8142..8588)
                     /locus_tag="IVW63_002282"
     CDS             complement(8142..8588)
                     /locus_tag="IVW63_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAP7860544.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8585..9589)
                     /locus_tag="IVW63_002283"
     CDS             complement(8585..9589)
                     /locus_tag="IVW63_002283"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP7860545.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(9629..9958)
                     /locus_tag="IVW63_002284"
     CDS             complement(9629..9958)
                     /locus_tag="IVW63_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAP7860546.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(10084..12411)
                     /locus_tag="IVW63_002285"
     CDS             complement(10084..12411)
                     /locus_tag="IVW63_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP7860547.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         3533 a         2435 c         2272 g         4243 t
ORIGIN      
        1 cctggaccaa taaaaagtaa agaaaaaata aaggaaaaga cattccttcc atctatcgac
       61 aaaaggaacg cagctgctat atacaagata ttgacacacc aaaaacaaag gctacttgcc
      121 aatgattgat acaaccaata aaagaattcc atataaacat ttttgtcaaa acgctgctct
      181 ttcataatca cctcctattc cttcattcct gatgaagcga tcccttctac aaaatatttt
      241 tgcatcgcta aaaatataaa agcaacagga agaacagaaa caactgaggc agccatgatt
      301 aatgcgtact ctgaatcaaa tagcccaata aacattttca accctaactg gattgtttta
      361 ttttccgtag aagacaaata aatgaatggc cccatataat cgttccatgt attaacgaat
      421 gtgatgatcg tcaaactggc aatcgccggt tttgtaagag gtaaaatgat cttgcgatag
      481 attccccact ctgataagcc atcgatccgc gcactctcac ataaagaatc tgggatacta
      541 ctgtagtatt gcttcaacaa gaacacacca aaagcattga acgcttgtaa tagcaccaac
      601 gaccacaacg tatatgttaa acccactttt ctcatcataa tgaactgcgg gatcatataa
      661 gactgccaag ggacagcaat cgtgccgata tatgctaaaa ataaaatatc gcgcccttta
      721 aaatttagtt tagaaaaccc gtaagcagca aaactagaag taaacaactg aatcaacgtg
      781 atcacaacgc ttaaaaaagc tgtattctta aaaaatgtca ctaaaggaat acgagaccaa
      841 ataaccagat aattctctaa atgccaagtt ttagggatcc attgaatcgg aatcgtgaac
      901 acttcattat ttgctttgaa tgaagcagaa accatccata aaaaaggaat gatcgtcaat
      961 aaagctaata caatcagcag aatcataccc aaccattgaa taaagggcat gttttttgaa
     1021 cgaatttttg ctttttttct ttcatttcga acacctccaa agttataatc ttcatttctt
     1081 tgtaatgatt acaatccaga acaacggtta ttatagctga ttcatttccg ttcttcttat
     1141 gtttgtaagc gcttatttaa caagttatgt aaatctcttt attttttttg atttaaaaat
     1201 gaaaaaatac aaaagcaaga ctgtcatacg tctcgctttt gtattgaaat ttcttcgatt
     1261 agagatactt attactgttc aaaagcttct ttgaaacggt gaatcaattc attgactaca
     1321 ggtgataaaa tccgattctt tttccagact agcatgcagt tcgtttcaat cattgggtca
     1381 agcggaacga atgtcactcg ctttgaaaga tgacttacag caccttctat gactaaagca
     1441 gcacctacct gattctcaat tagcgcaaat acattgaaaa tcaaattgta cgttcctgtg
     1501 atcagcaact gctccttttt tatgcctaac cagtcagcaa acattcgctg tatttctgga
     1561 cgctttgaga tcaaaagagg tacattcgca aagtcttctt ttgttatcac gtcttttttt
     1621 gctaaaacag aattttctaa aatgagcaat ccccattttt cctttcttgg taacaaaatc
     1681 gtttcgtatt tctctgtatc tactggatct agcaaaatcg ctaaatctaa caggcttttt
     1741 tctagtcact ccgtgatatc atcacttgtt ccgctgtgga tatgaaattg aacgctggga
     1801 taatcacgga tcaacttttc tagtaatagt gccaatgtat tcgaattatc agcttccaca
     1861 cagccgatcg taaatcggcc gctgaataat tgtttttttc tgttctcgaa ttcttgagtg
     1921 gtttgattcg ttaaatctaa aatttcttct gctcggcttt tttagaaaat aacctgcttc
     1981 tgtcaagatc attttgcggt tttcgcgtac aaacagttct gttcctagtt cctcttctaa
     2041 ctccttcagt tgtcggctta aggttggttg tgtaagatgt agaacttctg cggcttgaga
     2101 gattgttcct tcttctgcaa ttgtccaaaa atattttagt aagcgtaact ccatagcgat
     2161 gctccttgat ttttttactt gatacattcc attttatttc tagataacac acgatcatat
     2221 ttcttgattt ttccttgtaa acgttccaaa cactcttgca tttcagcaat ttctttcgtc
     2281 aaaagttcac tttcttcaat caaaagctta cgccgctcaa atacagttgc ttctccttcg
     2341 ctagataggc gaatatattc aatcaaagac tcgatcgata atccggcatt tcgcatacag
     2401 atcgtaaagt cgacccattt taggtcttct tctgtataat cacggattcc gccttttgtc
     2461 cgattaactg gtggaatcaa cccgattcgt tcataatagc gcaatgtatc ggccgaaatg
     2521 cccttttctt cactgacttg tttgatattc atctgatcac tctttctctt aatttcttgc
     2581 cactttactt atgtatttta tttattctac aactttaagt gtactccaag tcaatactca
     2641 tttctattaa aactaagctg gattatctat atcggttgtt tgtgtattat ttcaaataaa
     2701 aaagtcttgt ttttttattc ttttttggat atacttttaa caatttaggg aaattttagg
     2761 aaaaggggta taaaaatgac aacgtatcag cgaaaggtat tattatcgac atcggcggga
     2821 attgctttag agaatatgga tattatgttt ttagcttttt cattatcttc aatgattact
     2881 tcttttcata ttagtggtac gcaagcgggt ttcatttcaa cgatcactaa tttggggatg
     2941 ctcattggag gtattttttt tggcatcata gctgataaat atggacgtgt gaaagtattt
     3001 tctcaaacgg tccttctgtt ttcgattgct tctttattga tgtattttgc ttcaaacatc
     3061 tacttggttt atctctttcg ctttatcgca ggtgtaggag cgggaggaga atacggggcg
     3121 tgtatgtcct tgatttccga aagtttttca aaaaaacaaa ttggacgagc ttcttcggtt
     3181 gctggtattg gtgcgcaggt cggtgcggct ttggctgcga ttttagctgc tgtgatcatt
     3241 ccaacgtttg gttggaagat gttgtatgtc gtaggtgtac tgccggtgtt gatggtcttg
     3301 ttcattcgtc gcggcttgac tgaaccaaag gaattcaaat ctgtacaatc tgccgaaaag
     3361 aaaaccaaac ttagcagact gtttgaatca aaacatcttg cttggcaaac atgtggcctt
     3421 agtatcatgg taactgtcca aattgccggc tattttgggt taatgaattg gctgccttca
     3481 attatgcaaa atcgattagg gctttcggtt tctgggtctt cattgtggat ggtcagtact
     3541 attttaggca tgtctttggg gatgatgact tttggcataa tcatggataa attggggcct
     3601 aaactagcct tttctttgtt tttaatttgt tcatccttat ctgtctatct acttgtgtta
     3661 gcccatagcc agtggagttt ggtagcagcc gctgtgatag tcggctactt tatcaatggc
     3721 atgtatggtg gatatggcgc agtgattagt agtttgtatc caacagaaat ccgcgcgacg
     3781 gcgaataatt tcattatgaa ccttggacga gctgttggtg gtttttcttc tatcgtcatc
     3841 ggtttcttga tggatcatta tagtttaact gccgtaatct tgtttttgag cggtatttac
     3901 ctagtcagtc tgctggtctt gacaactctt actggtgtta cagcattaag ggaaagcttg
     3961 cagcattgat agttgagtct gtaaatgaca agaaagaggt gtggcaaaag cttgcatctg
     4021 cggtaataag accagccaaa tcaaaaacat gagacactgt ttccgtttgg ctggtcgtat
     4081 tacttgatgc agggcagctt tttcaactgc taatttcctt ctatctggcg gcgactattc
     4141 tttgacgtcc gtcatttcaa agtactttac taataactta gcataacgaa aaactgtgga
     4201 tacactcgta tattgagcgt ctgcataatc ttccaaattt ttctcaggat gttgatacat
     4261 gaattcaatc aaatgataat tatatgattt tctgtagaaa tgaagataaa taatgtagat
     4321 tgggaagttc tcctgctttt ccatagaaaa gcgccgatta ttctcattct tcaaaatgac
     4381 cttatcagga tatttttgga acaattcttc taaatctgtt agataattca agatagactt
     4441 acttgatacc ttcaattcgt tttgtagttc ttctattgaa caccaacgtt ctgtttcaag
     4501 cagtaaatga atcattttaa ttttcttttg agaaactttt gttaaaaaag tctgcatatt
     4561 ttctcctcct gtatctactt tactatacta catacaagaa aaaaaacgga tacaaatatc
     4621 atattgtcac accgtcaata gtgcataaac ctgttattat ttctcttttt ttcctaagta
     4681 ttctattgat atgaatcatt taatcgttta ttatataaat gtcaataatc taataataaa
     4741 ataacgtaca tattttatta ttgcatactt aataacagaa ctatagcaaa aaatcccgtg
     4801 tatcaacacg ggattagatt aagtttcctc aatcactatt cataacacaa ttattataac
     4861 aagtaagtaa acaattgaaa aggacattta ttgaaaacgg ttgtttttta cttaaggagg
     4921 aaatttagcg aaaaaattag ttgcattgtt tttggtcgca ggaagtttgt tgagtgggtg
     4981 tggtgctact acgtctacta ctcaaagcac aagttcagat caggcttcca gcagcagtac
     5041 cacgatctcc gaaagtacgg cagattcatc gaaagaacaa gaacaaattg aaaagaaaaa
     5101 agaagagaaa caaaaagcgg aaaaagctgc actagaaaaa aagtgacaga agcggaatct
     5161 gctttgtcac aagctgaagc aaatcctaca aaagaaaact atgcaactgc ttcagcagct
     5221 atccaagcgc tacctgaaaa caaacaagag ttgacaagcc gtcttgctgc aattgattcc
     5281 acaatcaaag caaaagaagc agaagaagaa cggaaaaagc aagaagaaat tgcacgacaa
     5341 caagcagaac aagcgcaaca agaagcaatc gcacagcaac aagcagaaca ggcgaggcaa
     5401 gaagcaatcg cacagcaaca agcagaacag gcgcgacagc aatcagcagc tgaacaggcc
     5461 tctcagcagg cacaagccgc agctcctgag caaaataatg aacaaactgt ctatgtcaca
     5521 ccgaccggtt caaaatacca tacacataaa tgtggaaatg gtacgtatac ccctgccact
     5581 ttaagcgaag ctcaagctcg tggtttaacc ccttgctcca aatgttatgg aaactaattc
     5641 aaaagttata ctataataat aaaattcttc tgaaacataa aaaaatagaa gatggcgttc
     5701 cagatagtaa accaaaaata acagtttaca cgtccatttc gtcagcttct ctcttttttc
     5761 atttagtctg ttccctctgc ttttttggac atcttcattc attctttctc aatcaaatag
     5821 tacacctctt tttcttttcg cagtttatat cttccttttt tcaatttcat tgaaaactgt
     5881 ttcgaatgtt tatgttttac atggatttta agcaggagct cctcatgttg caagcgatag
     5941 ttcctgcctt ttaaatcaga aaatctcact agtccgtatt catcagaagc tttcacaaat
     6001 ggaacttttt ctctagtaat atagtgtttg ccgttgagcg tttttacaga aaagaccatt
     6061 ccttcgattg gtcgtccgtt tgtgttcttt acataaaaag ataaaggata gtttcgctta
     6121 gcgatggcca aagaatctaa ataagcgatg agtagccaaa ctaagccgat tgatccaagt
     6181 agtataccga taaaccaaat aaaaaatttc cattttttcc attgatcaat tccttggatc
     6241 gctttttttg cctcttttgc ttgataagga atacgatgcc ccgtcacaag cagtcgatgt
     6301 gtattgacca tataaggagt acaggtaagc aaagtcacga gatctctgcc tttttggata
     6361 cccaaagaat ctacttcatc aggtaagacc acttggattt tttctacttg atacgccaat
     6421 gtctttccat tgatctggat gaaaaactgg tctccttttt tcaacttagg caaatctgta
     6481 aataattttg cttctgggag tccacgatgc ccagaaagaa cggcatgggt gtttttcccg
     6541 ccagtcggat aagaactttc ttccaataat gacgttcctt tttgcaaaaa tatttccgtt
     6601 gtctgatcga atataggtaa gctgacattg atttttggga tttcgatgac tccaagcata
     6661 tgttccataa aaaaggcatt actaggtaaa tcttttaatg cttttgcatc aactgcttgg
     6721 ttgaaactgc ctatccctgg tgatacgttt tgctctgcca actgttggtt tttctttgtc
     6781 attttttcct gctgtttttt tatttcctct gaattcttat tcgatgcttg cttttgataa
     6841 tggatgatca tttgctgggc aagaaaatca ttcagtgaat cttctacaaa aggataagaa
     6901 aagatcccga tcccaacgac taaaatgatt gccatgaaga tgtccagtat tcttattctg
     6961 cttttattca tcatgtccac ctattttcta atatgtatat gaagaggttg tgaaatcagc
     7021 gccttgacct gagtattagc gaagcaaacg gcaaaatagt tcctcctatt ttgccgtttg
     7081 ttgagcgaat accaagagac cgaccacttg tcacaacctt tctccccatt tgaatcacta
     7141 tcgtttattt atcgtatgat ttttgtttcc aatagtttaa gcttctgttt cttgatggcg
     7201 ttttttgaaa tagatcactg ctcctccaac taaagcagta cctaccaaga tgaatacgat
     7261 gatccccata ccaccagttg aaggcaagat tcctttaggt tggttatcga tcgttgtttc
     7321 atcagaagtt gttggatcat catctactgt aaattcagtg tacgcagctt cattcttagg
     7381 taatgcgtag ccttctggtg cttttgtttc ttgaaggcag tatgcccctt gtttcagccc
     7441 ttcgattgaa aatttccctt ctgaatcaga aatcaatttc acttcttccc agtcagaacc
     7501 tgtgacttca tctgaccaag catatgggta ttctcctgag gcaaggtttg ctattttttt
     7561 cattaattta acagttggat cttttgctct tagaatagaa aattctgcat cggctaattt
     7621 ttcttgcgtg ttcacatctt gtttgatgaa gtggaaatca ccgtagtttt ggacattttc
     7681 tacagtaatc atgttatccg tagttgtatt ttcccgattg actacaccgt ttggattccc
     7741 aagattggct tcatctgcgc catggatgat accggttgtt tgttgcaatt ttccgttttt
     7801 tactataaaa gtagtttctt tttgtggatt ggttaattga taaccatctg gtgcttttgt
     7861 ttcaactaaa gtataattgc cgtctattaa tccattgaca ctgatggatc cttcagtatc
     7921 agttgtgaat gtcaacgctg actcagcagg atcatagaga gcgacaccag tgttttcatc
     7981 aaaaccggtc acgaattgat tctctgaatt tttgatctgg aattgcgccc ctgctaactt
     8041 atctacccct gaaaagttcc cagctttctg gattttgata ttgctttctt tgatgacatt
     8101 tttagcatat aggtgaatcg tgtctaaagg tttgtcaggg tctagggtaa gcttaacacg
     8161 atatttggcg acgtttcgac accgggcttt ggtgtttcta caaagacgta tacagcatct
     8221 ttcccatcag atttacctgg aagagtcagg ttagctaatc cttcaccaga agtcgttaca
     8281 cttgcgaagg gtgtagcgtc tgctggaact gctgtgtctt tacttggata gtacgtagca
     8341 gtgatgtcat atacgttgaa ttcaacgccg ttcaacggtt cgctattcgg aaatgtcaat
     8401 tccgttccgt tgtttatttg attttctggt gctgaagtga atttcaattt atgcaaatta
     8461 accgtaacat tttctggtgt aggtgatacg gctgcagaaa cctctgcagt tcctaggccg
     8521 agaacgaaag gaagcagcat gatagcagtt cctaaaaacg tccatatttt tgttttgatg
     8581 tttttcattt tatttccctc ctattgtttc ctttttgttg ttttttataa aaccaagctg
     8641 tccctgttga aaggactagc aataacccta aaattgagaa acctccaagc atctcttcgc
     8701 ttgtttttgg aaagcttcct ccattttttt catttgatgg accatttgtc tgcatctgaa
     8761 ctggcgtttt tccattattc gtcggatttg cttttggttc gttgatgatt tccaatggta
     8821 taggatgaag cggatcataa ctgccttttt caacttcaaa gagaatggtt gattgactca
     8881 atatatatcc tttaggcggt ttaatctcca ctagttcgta acttccaaaa gacaatccat
     8941 ggacagaaaa tgttccatct ttactggaag taaaaatcgt tgctcttgaa tcatctttgg
     9001 ctacccaatg atttatcccg ttttcttgcg ctaagtattg gtcatttttt ttgactagaa
     9061 attgagcatc tgctagtttt tgtttcgttt gccgatccac tttgacaaat tgtttgcctc
     9121 ctgtttggat ggcaagatgt gtttctactg tttgattgtc agtcgtcaaa cgtacatcgt
     9181 tatcaaatgt cgttttttca ctgttttctt tcaatgtcat ttggtaacgg atcgttaatt
     9241 tttttccagc aaacgaacta agatcttttc cagaatctga taagacaaaa ccatgtttta
     9301 ttttttgtgt gtgaaatgta tgaatcttgt ctccaccaat caaaaaatcg atcgtttctg
     9361 gttctagcca taactgagga tcagctgtat ctttgatcgt ataggttcct atctcgttga
     9421 tgttctcagg aattgttacg gtgatgagat aagggacttt atccccatct gcaaaatctg
     9481 tctgcttatt ctctactgtt tttgttaatg tgagtgcagc aggtattttt tgttcgctct
     9541 ttggatacaa gtggatggtc gtcaatttat gattagatga atctgtcaca ggaagcacaa
     9601 cgacaaatgg tgctgatttt tcttttactt aatctgaagt ctttatttcc gtaaatcggt
     9661 aaacagcgtc acgaccttgc tcatctttgt ccgatgcact aaaagaagca atgccctctt
     9721 cctcgtctac tgtttttgtc acattttctg ccagtatttt ttcactatca cttttttgtg
     9781 ctagttttct ttgtgcgtct tccacactac ttccttctga ccgcagcttg taaaattcat
     9841 ccgagacatc atatatagcg aaagtaacgc cgttcaaccc ttttactcct tgaaagttat
     9901 ccgggatatt tattccgtcg ttttgactga tacttggcat cttatcgctt tcgaacattc
     9961 gattatgcaa agtaaatgta ataggtgatt ctctagctga cacagtcgga gaacctataa
    10021 aaaagaccag taggataaaa aagagaacag caaatatatc cacacgtaca ttttttgttt
    10081 ttttcatcgc tgttcacctg cttttttctt acgatggata aaataaaaga agccagaaaa
    10141 aataaagatc agtcctaaaa agacaaaggg cagtagacct atcccacctg tcgaaggaag
    10201 caagagagtc ggattgatcg tcaacttagc ggtatctgtt gcgataatcg tataattatt
    10261 gtttacactt ccttcgccta aactaatcgt tactatttgt gatccaatat ctgtccggct
    10321 gttaactgtt agggtataat ccaatgattc gcctaagaca acaccggtaa cgtggagatt
    10381 tccaaccgaa atcgagtgac tttgggcatc ataattaaag gcagcgtcat cgacagtaat
    10441 cactgcgtta gctttataga tggtataagt tcctgatgtg ttggctatat cagtaaatga
    10501 caacttggga tttgctgctt tgactttgtc tattccgcta ttcgttagtt taattgtata
    10561 gctgccagca ttaaccatat tttttgctga ttgtgcatct gctgtgtaat ccatactgct
    10621 aagtgccact tgtactggag taagcgaact agtgacaccc tctgctagct tgacatggat
    10681 tgacgggaca cctgcttttc catcatatgt cttactgcca ctgagctcta ccgcaccgct
    10741 gatttgctta atcgtataga catcagatgt ctgcacgata gtaaataaat agtttgttct
    10801 ggcagctagt ttagctagtc cgctttttgt caattgccaa gacgtatagg ttccaatttc
    10861 agtaggcgca gttacttcaa ctcccttttc attcatcgct ttgaaatcag ttggattcca
    10921 tgtgatttga tcaatactga gatcattgtt taaaagggat gttgattctg ttttatcatt
    10981 aaaggcatat ttaacgatcg gtacaacaga aagaccatca tagtacttac tgccatttgc
    11041 attgattgat actgttgcat ttgtcttata atataggatg acttcagaaa tctgttttcc
    11101 atttgcgtcc tttacgatta catttccatt tgtatctaaa ctagctaaaa cactcattgc
    11161 tgattggttc tttgtttcta tcgctgaaac agctgtaaag gtatatccgt tgatagtagg
    11221 cgtattagtc gtcaggtctt gtgcagcact tccgtaagta agattcatta ttttagaagg
    11281 agcaatcatc tgtccaaaat agtcttgata cttaatagtg attggtgttt gtttgcctgt
    11341 ataggtcacc gtatcgacgt tactttctag ggctgtgaaa gaaccgtttg tttgtgcaaa
    11401 agaatagccc gttactgctg ttggagtgat aaccactttg tcacccacat ggattccaga
    11461 taatgtagtc ccgtacgttc cgatttttgc tgctccacca ttgactgtat aagaaaaagt
    11521 tcctgtccga ttcgcattga cctgaaccgt tgctgcttga taggttggaa aatttgaaac
    11581 atttccctta ccatcaacga tctgcccatt tttgatcgag taccccgtga atggaatatc
    11641 atttgctaac tgtataccga ttgaaaaagt actcatacct cctccggcag gaagccctcc
    11701 ccatgttgag ggtgtaaaag aataactttt atccgcattg ggtgtaactg aatcgatcgt
    11761 atttccagcg gtagccaccc ccatatagat actttttggg aatgtgatag tagtaccatt
    11821 tactgtggag ccaataaaca gattatggat atctggacgg ttatcaataa aagcgattgc
    11881 tttggttacg ccttgtaacg cagttttatc cgcactcatc gatccgttaa ccgcaacaat
    11941 gactccatct ttggcatata tcactgtata tccatctggt atggtatgtc cgttgaaatt
    12001 cgcagtggcc gcaacagtac taaatgtctg gcttctacct gtttctgaat aagctttctc
    12061 ccctgctgct tttgctgctg tgatttcttt ttctgtcgga tcaatcagtt gagtcgagga
    12121 tgtggttgag gttgtctcgt tgttgctaga ctgattggtg ctttctatgg actgtatttc
    12181 agaatagggt ggactatttg tctcctctgt cgtttggtta gcaaaatttg acgtttctgt
    12241 ataaacgttt acataaatac ttgataagct ccctaagaaa gtaaaaatca agatgatcga
    12301 aatcataatg ggatgtaagt attttctttt agatacagct ttgagtctag aaacaaaatg
    12361 tttttgacat atacgttgga ttttattttg agttttctta atcattttca tccctcctct
    12421 caataaaaaa tcatcaaata atcctttaca cgttattcta aatttaattt ttattatttt
    12481 att
//
LOCUS       DACCVZ010000083        12085 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.086, whole genome shotgun sequence.
ACCESSION   DACCVZ010000083 DACCVZ010000000
VERSION     DACCVZ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.086"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(26..583)
                     /gene="frr"
                     /locus_tag="IVW63_002286"
     CDS             complement(26..583)
                     /gene="frr"
                     /locus_tag="IVW63_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAP7860548.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(586..1308)
                     /locus_tag="IVW63_002287"
     CDS             complement(586..1308)
                     /locus_tag="IVW63_002287"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010761216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAP7860549.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1444..2325)
                     /locus_tag="IVW63_002288"
     CDS             complement(1444..2325)
                     /locus_tag="IVW63_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAP7860550.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2424..3206)
                     /gene="rpsB"
                     /locus_tag="IVW63_002289"
     CDS             complement(2424..3206)
                     /gene="rpsB"
                     /locus_tag="IVW63_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAP7860551.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3565..4044
                     /locus_tag="IVW63_002290"
     CDS             3565..4044
                     /locus_tag="IVW63_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HAP7860552.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4261..5352
                     /gene="phnW"
                     /locus_tag="IVW63_002291"
     CDS             4261..5352
                     /gene="phnW"
                     /locus_tag="IVW63_002291"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HAP7860553.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5345..5473
                     /locus_tag="IVW63_002292"
     CDS             5345..5473
                     /locus_tag="IVW63_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAP7860554.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5477..6022
                     /locus_tag="IVW63_002293"
     CDS             5477..6022
                     /locus_tag="IVW63_002293"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAP7860555.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6476..8167)
                     /locus_tag="IVW63_002294"
     CDS             complement(6476..8167)
                     /locus_tag="IVW63_002294"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAP7860556.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8587..9534)
                     /gene="arcC"
                     /locus_tag="IVW63_002295"
     CDS             complement(8587..9534)
                     /gene="arcC"
                     /locus_tag="IVW63_002295"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAP7860557.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9649..10668)
                     /gene="argF"
                     /locus_tag="IVW63_002296"
     CDS             complement(9649..10668)
                     /gene="argF"
                     /locus_tag="IVW63_002296"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAP7860558.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10759..11988)
                     /gene="arcA"
                     /locus_tag="IVW63_002297"
     CDS             complement(10759..11988)
                     /gene="arcA"
                     /locus_tag="IVW63_002297"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HAP7860559.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3292 a         2520 c         2191 g         4082 t
ORIGIN      
        1 ccgcccctct gtttttatga ttttattaaa cttccaataa ttctttttct ttatcagcag
       61 cgatcttatc tacttctttg atgctgttat ctgtcaatgt ttgtacgtct ttttctaatc
      121 cgcgcaaatc atcttcggta atatcaccat ttttttgttg ttttttatat tcatcgatcg
      181 catcacgacg gatgttacga atcgcgattt ttgcattttc tgcttctttt ttaacatctt
      241 tagctaattc ttttctgcgt tcttctgtca gttgcgggat aactaagcga atgacatttc
      301 catcattggt tggactgatt ccgatatcac ttgccataat agctttttca acatcttgaa
      361 gaatgctctt gtcaaaaggt gtgatcatta aaacacgtgc ttctggaatt tggattgatg
      421 ccatttggtt caatggtgtt ggcgcaccgt agtagttcac agtaatacgg tccaaaaggc
      481 tagcgttcgc acggcctgcg cggatttgcc caagttcacg ttgaagattt tgtgctgctt
      541 ttttcatttt ttcttttgct tctgtcataa ttgcatctgc catttttatt tcccccttac
      601 agttgttccg atattttcgc ctaagattgc acggcgaata tttccgtgtt catttaaatt
      661 gaagacaagc agtggaatat cattatccat gcttagtgaa cttgcagttg aatccatgac
      721 ttgtaatcct ttggcaataa cttccagatg agtcagttct tcaaatttta ctgcatttgc
      781 atctactttc ggatcagcag aataaacacc gtctacattg tttttagcca tcaggataac
      841 atctgcgccg atttctgccg cgcgtaatgc tgctgttgtg tctgtcgaga agtacgggtt
      901 gccggtaccg cctgcaaaga taacgatccg tcctttttct aaatgacgtt ctgctttacg
      961 gcgaatatat ggctctgcga tttgacgcat ttcaatcgaa gtttgcacgc gtgtcggtac
     1021 acccacgttt tccaacgtat cctgtaaagc taaggcattc ataactgtag ctaacatacc
     1081 catgtaatca gcttgagcac gttccatgcc catttgtgct ccgatttgtc cgcgccagat
     1141 atttccgccg cccacaacga ttgccatttc aacgcccagc tcgtgaactt ctttgatttc
     1201 ttggatgatt tctttgatta ctggtggttt gattccaaat cctgcgtccc cagctaaagc
     1261 ttctccactc aattttaaga ctacacgctg atatttcggt gtgaccatgt tcattcctcc
     1321 aatattttct attgccattt taccatactt agatgatttc gacactctaa gactggtttt
     1381 tcttgttttg cttaaaaaaa gggagcgcac aaaccgtgcg ttcccgtctg ttattcaaca
     1441 gaattatttt ttcacttggc tcataacttc ttctacaaag ttatcttcgc gtttttcgat
     1501 accttcgcca acttcgaaac gtacgaatgt tttaacagtt gcgccttttg atgcaacgta
     1561 tttttcaaca gtcatatcag gatctttaac gaatggttgg tccaccaaag cgatttctgc
     1621 tttgaatttc ttcaagcgtc cttctaccat tttttcaacg atattcgctg gtttgccttc
     1681 gttcaatgct tgttctgtaa gaacagtttt ttcatgttct aattcagctt ctggaatttg
     1741 tgattcgttt acataacgag gattgatagc tgctacgtgc atagctacgt ctcttgcaac
     1801 tgtttcgtca gttgttccat ctagaacagt caatacggca atacgtccgc ccatatgcaa
     1861 gtatccacca aatgcagcat tgtcgtcttt ttctacaact tcaaagcgac ggaagctgat
     1921 tttttctccg ataacttgag ttgcttcgat caagtcagat tcaattgtac ctttatctgt
     1981 tttgattttc attgcagctt ccatgtctgc tggtttgttt tcagcaacaa gttctgcaat
     2041 ttcttttact aaatcttgga acatttcgtt tttagaaaca aagtctgttt ctgagtttac
     2101 ttcaacgatt gctgcagtgt tacctttcac agcaactgaa gccaatcctt cagctgcaat
     2161 gcggtcattt ttcttcgcag cctttgccat tcctttttca cgtaaaagat caactgcttt
     2221 ttccatgtcg ccttctactt caactaatgc ttttttcgca tccatcattc ctacgccagt
     2281 catttcgcgt agttctttta ccattttagc tgtaacgtct gccatgttta actcctcctg
     2341 tgtgtttttc tttttaaaaa aagctgcttc aaaggagagt gaggcttgtc gcccagcctt
     2401 tgaaacagct ccatcattca aaattattct gctgaagaat tgtcgccttc aacaacatct
     2461 acgatttctt cgattgatgt tgctgtgttt tcttctgtga aatcttcttc aactacttga
     2521 tcttcacctt ggtttccttc gatgaaagca tcagccattt ttgaagtaat caatttaacg
     2581 gcacgaattg catcgtcgtt tgaagggatt actacgtcga tttcatctgg atcgcagttt
     2641 gtatcaacca tagctacgat tgggatattt aatttgtgtg cttcttgaac agcaatacgt
     2701 tctttacgtg ggtcaacgat gtacattaca tctgggattc ttggcatatc agcgataccg
     2761 cctaagaatt tttcaagacg ttcacgttct ttgttcaaac cagcaacttc ttttttaggt
     2821 agaacttcaa aagttccatc ttcttccatt gcattgattt gtttcaaacg gctgatacgt
     2881 ttttggatag tatcccagtt tgtcaatgtt ccgcctaacc aacgatggtt aacgaagtat
     2941 tgtcctgcac gagttgcttc ttctttgatt gcttcttgtg cttgtttttt tgtacctacg
     3001 aataatgcta cgccgccttc ttcagcaacg ctcttcatgt aatcataagc tgcatctact
     3061 aatttaactg ttttttgcaa gtcaatgatg tagattccgt ttctttctgt gaagatatat
     3121 ttcttcattt ttggattcca gcgacgagtt tggtgaccaa agtgtacgcc ggcttctagt
     3181 aattgtttca tagaaattac tgccatgttt gtttcctccg atttggtttt atttttcctc
     3241 ttcttatctt ctaccttgcc ggcaaacttt ttcaagcacc taccgacaat ccaataagaa
     3301 tgtggatttg ctgatgcata aagcaccctc agctattata cagacaaaag atccgtatcg
     3361 caagagcaaa tatacttttc tgctcaacat tcaatagttt acctgaaaga taaaaagaat
     3421 tcaagaaaaa cagtagattt ctctttgttt ctttattatc ctttttccat aaaataattt
     3481 taggtataaa agacgaatat tattgggcaa tccttctttt ttttgttatg atacatgtga
     3541 aatctttcgt aaaggagaaa gaaaatgcgc aaagctcaaa gacatttgct gattaaacaa
     3601 gtcattgaag aattcccgat ccgtacgcaa gaagaactat taaacaaact tgggcattat
     3661 ggcgttaccg ccacgcaggc aacgatttct cgagatatcc gtgatctaaa aatcgtgaag
     3721 gcacctgatg aaaatggcgt ttcccgcttc gtattgtttc gcgaaaaagg aactcctgag
     3781 actaggactg aggaagagga tcggctggtt caaatgattg aagacattgt attgaaagtc
     3841 gaacgagtcc actttttgac gatcgtcaat accttgccag acaatgctca tttatttgca
     3901 tctgttttag atgagatcaa acctccctct attgtcagta caattgctgg attcgatacg
     3961 atcatggtca tctcggaaaa tgaggaggac gcaaaacgag tagaagaatt tcttcaccat
     4021 ccaactgaag tatcactttt ttaatcagag cacgtattcc taatatggaa tgcgtgtttt
     4081 tttattttca atattttcct tattgaataa acctttacac tctttacaaa aatacatcat
     4141 tttttattca aatttttcaa caccttgatt gaatcacaat aatcatcatt tatattggat
     4201 gttaacaaga gcagcttctt gctctttgtg tatttcaaaa aagaaatgaa aggaaatcat
     4261 atgtataaat tattaacttc tggaccattg acgacttctg aaacagtgaa aaatgctatg
     4321 ctgatcgatc attgtacttg ggatcaagaa tacaaagaaa ttacacaatg gataagaaaa
     4381 aaattattgg atcttgctca agtatcggaa ggaatataca caacggtctt aatgcaaggt
     4441 agcagctcct tcggggtaga atcggtatta agttctgtga tcaggccaga agatactgta
     4501 ctgatttgtt caaacggcgc atatagacaa cgaatgatca acatgtgcga atgtctgaaa
     4561 ctgaactata ccgtttatga ggtatcggaa catcaaatcc tccaagctca tgtgattaca
     4621 cagctgattg aagagaatcc gtctatctcc gcactagcaa tggtccatag cgagactact
     4681 tccggtattt tgaataattt ggaagagatt gctgctgtca cacaagaaag agatcttttg
     4741 tttatagtgg acgcgatgtc aagctttggt gggataccga tttgtgtagc cgaactaggg
     4801 attgattttt tgatttccag ctcaaacaaa tgtattcaag gtgttccagg cttttctttt
     4861 gtacttgcta ataaagcgga actggaaaaa cgaaaaaatg ttagccgaag tttgtcactt
     4921 gatctatatg accagtaccg cgtgatggaa aacgagaatg gcaaatggcg tttcacttcc
     4981 cctacccata cggttttggc ttttcaacaa gcgctgaagg aactagaggc agaaggagga
     5041 atcgaaactc gatattcacg ttatctcgcc aataatcatg tgctacgaca aaaaatgaca
     5101 gagatggggt tccagccttt cattcaagaa tatcaggggc cattcatcac ctcttttctt
     5161 taccctaagg actggcgatt tgattttaat catttttatc agtatttaaa gcaaaatgga
     5221 tttgtgatct atcccgggaa aatcagcgat catgaatgtt ttcgtatcgg aaatattggc
     5281 gagatctatc cggaagatat tttggaactg acagcaatta tcaaagacta taaggagaac
     5341 gttaatgatt aaaactgtaa tttttgattg ggcaggaaca actgtggact ttggctgtat
     5401 ggctcctgtc cacgctttta gaaatgcttt tctagaaaaa ggaatccaac tgactgacaa
     5461 agaaatccgc taaccgatgg gaaaattaaa atgggatcat atccaacagc ttctttccct
     5521 cccttctgtc aaaaaacaat ggatagctat ttatggacaa ctacctcagg aaaaagaggt
     5581 ggaggaattg tatcaacaat ttgaacatta tctgtttaaa gatttggtca agcattctac
     5641 cttgaaaccc gacacattgg aaacgatcga acggttgaga aacgctggga tcaatattgg
     5701 ttccacgaat ggatttaatg ctcctatgat gacaatcgta gcagaaaccg caaaaaaaga
     5761 aaggtattca ccagacttca tggcaacttt tgaagacgtc gaagggtatg gtcgaccgtt
     5821 tccttatatg atccataaaa acatgcagta cttcaaaaac aagtcggttg atgaagtaat
     5881 caaagtcgga gatacggtct cagatatcca ggaagggaaa aatgccggag tgttgacagt
     5941 aggtgtaatt gaaggtagtt cgctaatggg gatttcttat gatgagtacc aaaaattaga
     6001 gatggggaaa aagatcgttt aaaacagtct gttgctctta gattccaaca agccggcgct
     6061 gatatttgtg taaacaattt aaaagagtta acagaataca ttttgtacgc tgacatgaat
     6121 ccagaatgac ttttatacaa aataagaggt tgtgaaaaag ctgtcctgta tcaagtaata
     6181 aaaacagcca agcaaaaata gctcctcata tttttcgttt ggttaggctt attaccgcag
     6241 atgcaagctt ttgaacaccg tttattcgaa aaaaaaaagg gagctgtgac acgacttttg
     6301 tcacagtccc cttatttgca aacaaacagt gtttaagaga caacctctcc actaaacggt
     6361 gttcattcag ctgactctcg gtatttgctc aaaaaacgat aaaatttgaa aagctatttt
     6421 ctcttttgtt tctctaatac tcggatcaga acgctgattt cacattctct ttttcttaca
     6481 tcttatctgg tgcatgaagt cctagcaaac gaaggtcttc tttcaataat acagtcactg
     6541 cataaactag agctaagcgt gcttcttttt gttcatcatc agctaaaatc ttcgtatgag
     6601 catagtattt gttgaatgct tgtgctaatt tgattgcatg tttcgcaatc actgacggtt
     6661 cgtatttttc cccagcagac aagaccgttt cagggtattt ttgaactaat ttaaccactt
     6721 cccagctggt atcgtcattc aatgcatagt ctgctgtttc tgaagggaca aatcctgctt
     6781 tttccaacag gctgactgca cgagcatgtg tatattgcac ataaggtcca gtttctcctt
     6841 caaatcgaac aacttcttcc aggttaaagt caaatgtatt cagtcgatcg tttttcaaat
     6901 cgtggaaaat gactgcccca accccaactt gtttagctac agcatctttg ttttccaaat
     6961 cagggttttt ctcgctgatt tgttctttag cagattggat tgcttcattt aatacttctt
     7021 ctaataagac gatctttcct ttacgagttg ataatttttt accaccttgc gtgatcaaac
     7081 caaatggaat atggtgcatg tcgtcagacc agtcaaagcc catttccttc aagacagctt
     7141 tcaactgttt aaaatgatag ctttgttcat tccctactac atatagagat tgtttgaagt
     7201 cgtaagtacg tttacggtac aatgcagcag ctaagtcacg tgtaatgtat agtgtcgcac
     7261 cgtctgactt cttaatcaac gctggattca ggtcataagc agataggtca acgatctctg
     7321 cacctttatc ctcgttcagc aaatgttttt cttctaaaag tttgacgatt tcatccatct
     7381 tgtcattgta gaaagcttca ccgttcaacg aatcgaaacg tacttccagc agatcataga
     7441 ttttattgaa ttctttcatc gattcatcac ggaaccattg ccataattga atagcctctt
     7501 tatcgccttc ttccagacgt ttgaaccaag cacgagcttc ttcatttaat tctggttctg
     7561 tttcagctac ttcatggaat tggacgtata aacgaagcaa ttcattgatt ggttctgctt
     7621 taacagcttc ttctgtaccc cattttttgt aagcgacgat cagttttcca aactgtgttc
     7681 cccagtcacc taaatggttg atgcggattg gctgataacc gattttttcc ataatgaaac
     7741 cgatcgaatt accgataact gtcgaacgca aatgtcccat tgagattggt ttggcaatat
     7801 taggagaaga catgtcgatt ggtactgttc cttgattccc gatgttgcta tccccataat
     7861 gttctttttc tttcactact gtttgcaaaa cttttttgct gataagttct ttattcatga
     7921 aaaagttcaa gtaaggtccg acaacttcga ttttttcaaa gttggcagaa tcgatttttt
     7981 ctgctaaatc tgcagcgatt tgctgtggcg cttttcggta aacttttgct aatgaaaagg
     8041 ctggaaatgc aacatctccg tgttcagctg attttggatt ttctagtaat tgctcgactt
     8101 gttccagtgt taaatcatct ttgacagcgt catagacagc ttttgcgaca agatctttat
     8161 tattcatctt tattcctcct aaagtgttcc cttgattgtt aaacaaaaaa aatctctagc
     8221 gacggcatac ttagtatgcc atcactagag acgagatttc ccgcggtacc actccaattg
     8281 tcctaaaaaa ggaccagctc catctgatat cggtagacga ccgtctgttt aaaacagaat
     8341 tctccaagtg cgcttcgttg tatcttcttc attcggcttc caccacttcc gaattcgcta
     8401 gccaagaatg atacaagtac tctcttgttc aacaaatctt agtcttatta aactttcttg
     8461 aattatatca gaaaaaaaaa cgaaaggcta gtcgtttcat aaaaaaacaa tccagatggc
     8521 ctaaaggaga agaaatacca cctggatagc tataaatcat ttcgtaaata cgaaagactt
     8581 aacaaattaa tcagctacga taatcgttcc ttcttcagaa gctaaaagat tctcgatatt
     8641 ttctaaagaa gtgatgattg ccttagcgtt tggttttgct tcaacaaatg caatagctgc
     8701 ttctactttc ggaagcatgc ttcctggagc gaattgcttt tcatcaatgt attgtttcat
     8761 ttctgaaaca gtaacagttt ctaatttctt ttgatctggt ttttggtaat tgacatacac
     8821 attgtctact cctgtcaata cgatcagcaa atccgcatcg atgatttcgg ctaatttttc
     8881 tgaagcaaaa tctttatcga ttacggcttc tcgtccttct aatccagtag ctgtttctac
     8941 aacaggaatc ccaccgccac caacagagac tgtgataact ccttgatcga ccagcgtttc
     9001 gatgacacgt gcttctttaa tcgagatggg tttaggggaa gcgactactt ttctccatcc
     9061 acgtccagca tcttctttga atgtcacagt ggagtcagca ttcatttgtt ctttggcttc
     9121 ttcttccgtg tagaatggac cgactggttt acttggattt ttgaatgaag gatcattttc
     9181 atccacaata acttgagtga ctaaagaaac cacatcttta tcgatccctt tttccttcag
     9241 tacttcgccc atggcgtttt gtaaccagta accgatagat ccttctgtca ttgcaacaca
     9301 tgtatctaaa ggcattgccg gtgttttctc agaatcagca gcttgctgct gaatcaatag
     9361 gttaccgact tgcggaccat ttccgtggga gatgatcaat tcatctcctt gttcgataaa
     9421 tttcactaaa tactttgctg tttccattaa cgcttcttgt tgggcttttg cacttgcatc
     9481 cgtagacaag atggcattgc cccctaaagc gacaactact tttcgtttgg ccatttcatt
     9541 cgtcctttct tcagttctac cgaattttct agataacaaa acgagccagc gttttgtgat
     9601 tttccctcaa tgctgactcg ttttttcgtg agatgaatgt ggttatgctt aaacgcgagg
     9661 gataaacaag ttacctaatg ttgctgccat gatcgctttg attgagtgca tacgattttc
     9721 tgcttggtca aattgacgag catatttgct gcggaagact tcatctgtta cttccatttc
     9781 agtgatgcca aagcgttctt tcatttgttc accgtaaaca gtgtttgtat catggaaagc
     9841 tggcaagcag tgcaagaaga tcaaacgatc tgtgttgtgt gttttttcta ccatttccat
     9901 attgatttgg taaggtttca acaatttgat acgttcttcg aatttatctt cttcacccat
     9961 tgatacccat acatcagaat aaaggacgtc tgctccgtct acacctttat caacatcgtc
    10021 ggtaatcatc aattgtgcac cggatttttc agcaaagcct tctgccattt tgacgatttc
    10081 ttcttcaggt tgtaattctt ttggtgcaac gatacgcata ttcgctccta aaattgcacc
    10141 tgtgactaat aaagagttag ccatattgtt tcgaccatct ccgcagtaag caacagtgat
    10201 accttctact gttccaaagt tttcttggat agttaaaaag tcagcgatca tttgtgttgg
    10261 atgccattca tcagtcaagc cattccaaac tggaacacca gagaattctg ctagttcctc
    10321 taccattttt tgactgaatc cacggaattc gattccgtca aacatacgtc ctagtacttt
    10381 agctgtatct tctgtggatt cttttttacc taattggata tcatttgcac ctagatattc
    10441 aggatgtgca cctagatcga tcgctgcagt agtaaatgca gaacgagtac gtgtagatgt
    10501 tttttcaaat aaaagcgcaa tattttttcc ttctagatag tgatgtggga taccacgttt
    10561 tttcaagtct ttcaagtgtt ctgaaaaatc gatcaaatat tgtaattctt cttttgtaaa
    10621 gtctttttct gctaataagc ttcttccttg gaatactgat tctttcatat taaacattct
    10681 cctttagatt gtttttattt aagattaaag aggaaatccc gacggcagct gacagtaaga
    10741 ctgccgtcag gaaacaaatt acttcaagtc ttcacggaca agtggttggc tcatgcagcg
    10801 tggaccacca cgacctcgtg acaattcact tgaattgatt tctaacactt tgatgccata
    10861 gctacgaagc aattcgttcg atacataatt tcggttataa gtgactacaa cacctggagc
    10921 gattgccaat gtgtttgatc catcattcca ttgttctcga ggtgcaacga tctcatctcc
    10981 attaccagtt gggatcagta caagatcatc taatccaaga gcagctttca tcgtttcgtg
    11041 taagttatct gaatgagtaa tcttgatatc atcaccatct ggttcgattg taaagacatc
    11101 catcttaccg tctttacttt gaattgctgg atggatagtg aatttatcgt gatctaccat
    11161 tgtaaatacg gtatccaaat gcatcattgc acggttgttc ggaattttga ttgccaacac
    11221 tttttcaaat cctgaatttt ttgcgaatag gtggcgtgct aatttttcta aagctttcgc
    11281 attagttcgt tgagaaatcc caacagctac tactttatcg cttaagatca attcgtctcc
    11341 gccttcgata tgatctggat tttcacgatc caaccatact tcgattcctt tatttgcaaa
    11401 tcttggatga tgtttcaaaa tatattctgt aaacatcgat tcacgacgac gtgcttcaaa
    11461 agtcatctta ttgactgtca tcccatttcc cattgatgcg gaagggtcgc gtgtaaagta
    11521 caagtttggc attgggtcca tgtaaaatgg atagtcatcg tctgctgaca gatcatatag
    11581 actgctagaa cgtacttcga tatcttttgt acgaacccca gccatgattt tatctaccat
    11641 ttcttgcgtt tccattgata gaaggaactc atgaagaccc tctcttacag cattcgatgc
    11701 aatatgagat tcatccaaca ttttattcaa gaattgttct ttgacattgc ctgcgtcaat
    11761 cgcttctgcc gctaattttt ccaagtaaag agtctcgacg ccttcatttt gcaatgtctt
    11821 cgcaaagttg tcatgttctt cttgagcaat cggaagatat ggaatatcat cgaacaacag
    11881 acgatccata atatctggtg tcaaattttc cacttcttgt ccaggccgtt tcagtaaaac
    11941 tgtctttaat ttccctattt cagagaaaac gtgaataggt ttatccatgt tgtgttgcct
    12001 ccttcttttt gattacatgt ataggatatc ctccttttgt aatcactttc ataattttgt
    12061 ctcattcaaa atgagacatt cctca
//
LOCUS       DACCVZ010000084        12046 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.087, whole genome shotgun sequence.
ACCESSION   DACCVZ010000084 DACCVZ010000000
VERSION     DACCVZ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12046
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.087"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            16..2034
                     /locus_tag="IVW63_002298"
     CDS             16..2034
                     /locus_tag="IVW63_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP7860560.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            2461..4875
                     /locus_tag="IVW63_002299"
     CDS             2461..4875
                     /locus_tag="IVW63_002299"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAP7860561.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            5223..6776
                     /locus_tag="IVW63_002300"
     CDS             5223..6776
                     /locus_tag="IVW63_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAP7860562.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(7157..8941)
                     /locus_tag="IVW63_002301"
     CDS             complement(7157..8941)
                     /locus_tag="IVW63_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860563.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(8956..10677)
                     /locus_tag="IVW63_002302"
     CDS             complement(8956..10677)
                     /locus_tag="IVW63_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860564.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            10777..11538
                     /locus_tag="IVW63_002303"
     CDS             10777..11538
                     /locus_tag="IVW63_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP7860565.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         3944 a         2179 c         2437 g         3486 t
ORIGIN      
        1 gttggaggat agaagatgga aaacattgca agaaaagaac ggagacgttt agaacagacc
       61 aaacgttttc gaaaagcaaa acgaggggca gcaatcgtgg gaactgcgat ggtaggctgt
      121 tctgtcgctg ccccattagt acagccggtt cctgttcaag cggatgaaac acctgttcag
      181 ttcggcgcaa gaatcaatac agcggcattt atcacagaaa ttgctactta tgctcaacca
      241 atcgctcaag ccaacgatct atatgcatca gtgatgatcg cacaagcagt tgtagaaagc
      301 ggttggggca gtagtgcgtt atctcaagca ccttattata atctttttgg gataaaaggc
      361 agctatcaag gacaaaccgt ctacatggat acgcttgaat ttttaaataa tcaatgggta
      421 aataaaaagg agcctttccg acaatatcct tcttttgctg aatctttcaa tgacaatgcc
      481 tatgtactta gaaatacttc atttggcaac ggttattact atgccggtac ttggaagagc
      541 aacacgaaat cctatacaga tgcgacagct tgtttgacag ggcgttatgc gactgatcct
      601 ggttacgcag gcaaattaaa taatatcatc gcaacttacg gattgaccca atatgataca
      661 ccagctagcg gaaacgcagg cggtggagcg actacaggtg gcaataatac tggaagtgca
      721 ggtagtactg gcggttcaag caattctggt aatacaaact caggttcagc aacttcgacc
      781 acttatactg tccaatctgg tgattctgtt tggggaatct caaataaatt cggtatcaca
      841 atggatcaat tgatccaatg gaacaacatc caaaacaatt tcatttatcc aggacaaaaa
      901 ctgacaatca aaggtagcca ggaaaatggc tcttcgacga ataattccgg taacaatacc
      961 aactcttcag gaaatgctgg tacatcaaac ggaggacaaa caactggtgc gaaatacact
     1021 gttcaatctg gtgattctgt ttggaagatc tcaaatgatc acggaattac gatggctcaa
     1081 ttgattgaat ggaacaatat caagaacaat ttcgtttatc caggacaaca gctaatcgta
     1141 tcaaatggcg gttcttctaa tgctggagca aatactggct caaatactgg gaatacaagt
     1201 ggctctagtt cgtccagctc aagttcttct aatacagctt caggaacgaa atatacagtt
     1261 aaagccggag actctgtttg gagcgtctca aataaatacg gaattacgat ggctcagcta
     1321 atccaatgga acaatatcca aaataacttt atctacccag gacaacaact gactgtttca
     1381 aacagtggat caacaaacag cacgtcaggt aatacaggtt cgtcaaccaa tacaaataac
     1441 agcagttcag ttaatactgg cagcagttcg tctcaaggca cttataccgt gaaagcaggt
     1501 gaatctgttt ggagcgtggc aaataaaaac ggcatcacga tggatcagtt aatcgaatgg
     1561 aataatatca aaaacaactt catttatcca ggacagcaat tgatcgttaa aggtggaact
     1621 tcggcaaata caaatacagg ttcaactact tctgcagcga aaccaaatac accgaatacg
     1681 tctgctacga caagtacatc atccactggt aatacgatgt ataccgtgaa agcgggcgag
     1741 tcagtttgga gcgtagcgaa caaacatcat atcacgatgg atcagttaat cgaatggaat
     1801 aatatcaaaa ataatttcat ctatccagga cagcaagtga ttgtgaagaa aggttcatct
     1861 caatcaacaa accaacaatc agttactggt tcgaaaacct atactgtgaa atctggagaa
     1921 tctgtttgga gtgttgctga cagtcatgga attacaatgg ctcaactaat cgaatggaac
     1981 aatattaaga acaactttat ttatccaggt caaacgttga ttgtagctaa ataaaatagc
     2041 tgttcgaaga aataacgatt gaattccaca aaaatatttg ttactataag gctacttaaa
     2101 tatgacaaca cttgaaaagg aagtagtaaa aagactgaag tttcagagag cgcatggctg
     2161 gtgagaatgt gcacggatgc ttttgaactc gcctttgagt tgcccttgct gaatacccga
     2221 gtaagcaagc ggcggtgacg gccgttacaa cgttcgaggc cttttcacta aggtaaaatt
     2281 aggtggtacc gcgtagatta cgtcctataa aaagagcaat ctttttatag gattttttta
     2341 tttcttttgt gaagtttgag aaaacaaagc aaaaggaaat aaaaataaac agattctgcc
     2401 ggttttttcg ttatatttat aatagaaaca agtgttttca atagaacagg aggacagcaa
     2461 atgagttaca atcataaaga aattgagaaa aaatggcaaa aatactgggc aaaaacgaat
     2521 actttcaaca cccatgatga tcctgaaaag ccaaaatttt acgcactgga tatgtttccc
     2581 tatccatccg gtcaagggct acatgtaggg catcctgaag gttatacggc aacggatatc
     2641 ctttcacgtg tgaaaagaag tcaaggatac aacgtgctgc atccaatggg gtgggatgca
     2701 ttcggtctgc ctgctgaaca atatgcgcta gatacaggaa acgatccagc tgagtttacc
     2761 caaaaaaata tcgaaacatt ccgacgccaa atcaattctt taggatttag ttatgactgg
     2821 aatcgcgaag tgaatacaac tgatccggag tattataaat ggacacaatg gatctttacg
     2881 aagctttatg aaaaaggtct agcttatgaa gcagaagtag cggtaaactg ggtacctgaa
     2941 ttaggaacag ttatttcaaa tgaagaagtg atcgatggga aaagtgaacg tggtggctat
     3001 gatgtagtca gaaaaccaat gcgccaatgg atgctgaaaa tcactgctta tgctgatcgc
     3061 ttattggatg atctagaatt agttgattgg ccagaaagca ttaaagaaat gcaaagaaat
     3121 tggatcggtc gttcagtagg agcaaatatt gaatttaaag tggctggtac ggataaatcc
     3181 tataccgtat ttacgacacg accagatact ctattcggtg caacttactc ggttcttgca
     3241 cctgaactag atcttgttag agaaattacg acccctgaac aaaaagctgc tgtagaagct
     3301 tatatcgaag agacagctaa aaaatcagat ctaaagagaa cggatcttgc aaaagaaaaa
     3361 acaggagtat ttactggtgc ttatgcaatc aatccagtta atggcaagga aatcccaatc
     3421 tggatcgccg attatgtatt atcttcatac ggcacaggag ccatcatggc tgttccagca
     3481 catgatgaac gtgactttga attcgctcaa actttcggac tagaaattct tccagttatc
     3541 gaaggtggag atgttgaaaa agctgcttac acagaagatg gtacgcacat caactctgaa
     3601 tttctagacg gcatgaacaa acaagaagca atcgataaaa tgaatgaatg gctagaagaa
     3661 aatggcgtag ggaaaaaaga agtcagctat cgcttacgtg actggctatt ctcccgtcaa
     3721 cgttactggg gtgaaccaat cccaatcatc cattgggagg acggaacagt cacagctgtc
     3781 ccagaagaag agctaccatt acggttgcct aagacaaaaa acatcaagcc aagcggtact
     3841 ggagaatctc cattagcaaa tatcgaggag tgggtcaatg tcgttgatcc tgtaacaggt
     3901 aaaaaaggcc gtcgcgaaac gaatacaatg ccacaatggg caggaagctc atggtattac
     3961 ctgcgttata tcgaccctca taacaaaaaa gaactagcag attatgaaaa gttgaagcgt
     4021 tggctaccag ttgacatcta cattggtgga gcagaacatg cggtacttca tttactatat
     4081 gcacgattct ggcataaatt cttatacgat atcggtgttg ttcctacaaa agaaccattc
     4141 caaaaactat acaatcaagg aatgatctta ggcgaaaaca acgaaaaaat gtcaaaatct
     4201 cgtggtaatg tagtcaatcc tgatgatgtg gtcgaaactt acggtgcaga tacactgcgc
     4261 atgtacgaaa tgttcatggg gccattagat gcttcgattg cttggagcga aaatggctta
     4321 gaaggaagcc gtaaattctt ggatcgtgta tggcgtttga tcgttgatga gaacaataaa
     4381 atgcgtgacc gtatcactac attgaatgat ggcaagcttg ataaagtgta tcatcaaaca
     4441 gtgaaaaaag tgacagaaga ctatgaaaat cttcatttca atacagcaat ctcccaattg
     4501 atggtcttta tcaatgaagc ctataaagtg gacgctctgc cttatgaata tatcgaagga
     4561 tttgttcaac tactcgcacc gattgctcct cacatgggtg aagaactatg ggcaatcctt
     4621 ggaaatgatg gtggtatttc ttacgcacca tggccaacat acgatgaagc agcacttgtt
     4681 gaagacgaag tagaagttgt tttccaagta aacggtaaag ttcgtgcgaa aagcaatgtt
     4741 ccccgagact taggaaaaga tgagctagaa aaagcagcat tagccaatga aatagtgcaa
     4801 gaatatattg aaggcaaaac agtcagaaaa gttattgcgg taccaaacaa gttagtcaat
     4861 atcgttgcta attaattggc tctttgtcaa taaggactga tgagttgtgc aaaatcaaat
     4921 ctgggccaga atgaacttca ttctgtctca gattttttgt tatttcaaat tgattaattg
     4981 attgatcaaa aaggttttga ttttcatgtt ctcaaacacg ttcaatgtct ttttcttctg
     5041 aatggtcttg taagagatct ctgtaatcat caaatttttg tctattaatc ttagtatttt
     5101 ttgatgtata aactacctga aattgagagt acataccaaa ttcataaatt ttttattagt
     5161 gggactagtg attgtatgga ttttgacgca taatgaatga agtatgagaa aaggagagac
     5221 aaatggatca agaactattt attatcgaag tattatcagc taaacaaaaa attatcgaga
     5281 aagcgaaaaa aagagcgaaa agaataatgt tcaagctttt aagcttagta tttttctctg
     5341 gtttgctttt tttcggagct gtatcgttcc tatatcgcca tatgagtgca gtagtccgtt
     5401 cagctgaagg gatgcaaaaa ttaaataatt tgtatcactt ttcgtgggga gttggcggaa
     5461 taacaattgt tgtgcttatt gtttttcttc tacttatttg gctccgttac catcaattgt
     5521 cgcgtcattt cgatcaatgg cttagtcaaa gagcacaaca gtttttacat aataaaccaa
     5581 cttctcaaga tgatgactat ctttattttg agaagacttc gacgagtcaa gcttttcgga
     5641 tacaaaaaag tgattgccag ttattgctga gatcacttga tgatttacct atctacttag
     5701 gcgaaagcaa atcaaaattc ggaatgaaca cattccatat ttttttacta gaaaacgaac
     5761 ccagatggga aaaaagccag tcttcgcctg gtggatacct gacaactaag atgagtacat
     5821 tagtcactgg ttttttcctc attcttttag ctggaacaat ctattatggg agatacactc
     5881 agccaaaaat gtcttctcat ataaatgctg cttctcacat gacaatgaac tcaactaacg
     5941 atacgcatat acaaaagaca aatgaagggt tgttagctga tcctaagcaa aaggtaaatt
     6001 tgacaacaca aaagataaat gatctcaaac ttgatacaga gacgcactct ctctatatga
     6061 caacagatag tggtgctaat tgggtatttg tgccgattga ttcgcaatgg ttgcgttttg
     6121 gcgaatacac cctgacaacg gggctgattc ctgaaggtta ttggatggac aacacatatg
     6181 atatttccgc cgatttctca tggtttatct attcttctgg ggatgatgta cgtctgctga
     6241 cttcaagaga taatggtaaa acatggcaaa cgtctattat cacccaatca gttcagccga
     6301 tacgttatcg aaaagcggta ttttatggca acgatggtct atttatctgt acatcagcca
     6361 gtgggatgtc tgcagaaact ttgtacattt acactactat ggatggcgga atcacttgga
     6421 taaaaagtgg aagtacaatg atcaatcagc cagtacaaaa tgtcagcttc gttacaactt
     6481 ctttaggttt tgtttcgaca cgtgaaagtt tgttttatac aaacaacgga ggacgctcat
     6541 tcaaagaatc agttctgtcg attccggaaa actatcagac aggggggata gatctttttc
     6601 aatcaccaaa tgaagttact caaataagcg cgaatacgtt agagacaaaa ttttatttgt
     6661 tgaaaaaagg accaatcgat gcagggaaaa tgtttgcctg cctcttccgt tcaactgata
     6721 acggggaaac atggcaattc gttcagcaac tatcgcaagt agaacaagga gattaaagaa
     6781 gagagattgt gagcctgacg ttcagcaccg agtcacaaga aacaaattca aaaaacagct
     6841 tctcatattt gttgaatagt gtaactcgtg attcggagtt gacaagagca acaagaagcg
     6901 attttgaagt atagcttctc gtattttaca agatcgtgtc ttattgccga taggttgtct
     6961 cttgaacacc gtttattcgt aaaaagggat tgtgacaagt cttttgtcac tacttaccga
     7021 acgaaactga aggagctatc caaaaagtat cattagtatt attctttgtg tttctagtgg
     7081 caccactagt acatttaaaa aagctatcga tcatggacta atcatacatg atcgatagct
     7141 ttttagataa tgtttgttac gctatctgaa attgactatt ataaagactg gcataaagcg
     7201 ttggtgattg gagtagttca gaatgtgttc ctttttcgac gatatcgcca ttcttcatta
     7261 caaggatcat gtctgcattt tcaatcgttg acaaacggtg tgcaatcaca aaacttgtcc
     7321 tatcttttgt cacagcttcc attgcttgct gaatcaatgc ttctgttcgt gtatctacgc
     7381 tagaagttgc ttcatctaaa ataacgacag gaggattcgc tagaatgact cgagcaattg
     7441 tcaataattg ttgctgtcct tgagataacg tgccgttttc gctagaaatg atcgtatcat
     7501 atccgtctgg cagtgttcga ataaagtgat cacattgtgc gatttcagcc gcttcgataa
     7561 tttgttctct tgtggcatcc attttcccgt aggcgatatt atcagctacc gttccttcaa
     7621 acagccaggt attttgtaaa accatcccaa aagaacgacg tagttctcca cgtgaaagct
     7681 tggtaatatc aagaccgtcg aattcgatct ttcctttatt cagttcataa aaacgcatca
     7741 gcagattgac taaagtcgtt tttcctgcac cagttggacc aacgatcgct accgtttgtt
     7801 ttggctttac tgaaaaatcg acttgattca tcaatatttt atctgatgtg taaccaaact
     7861 gtacattttt gaaagctatt tttcctttcg gttgttctaa aagtcttgca tctggaaggt
     7921 ctggaatttc atctgtttca tctaatatct caaatatcct atcgattgct gccattgcgg
     7981 attggatcga gttgatcaca taagaagcgg tagaaattgg ttcagaaatc tgattgatgt
     8041 actgaagata agcttgtaag aagccgatcg tcacaccacc tgatagaaca agcatagcac
     8101 cgaataccgc acttatgatg aaggcgagtt gattaatgaa acgaatggcc ggatagatag
     8161 cacagttcat aaattgagca cgtttaaaag cgttgtattg ctttttattt acttcgtgta
     8221 tagcagcttc tgcatgagct tgctgattga atgttttgac cactagatta ccagctaaga
     8281 tttcttccat tcgattattt aaaacaccca gttcatactg attctgttca gaaatctgtt
     8341 tgtttttgtt cgcaatctta gttgtaacaa ttgaactgcc aacgatcagc aataagacga
     8401 gcaaagtaag cttgctttcg atataaaaca gcatcagacc agcagcagct attgttacga
     8461 cagaagtaaa aaattgattg atacctgtca ataacacttg agaaagttga ttgagaccgg
     8521 tagttgtccg actaatgatg tcacctactt gatgattgtc aaaaaacgac atcggtaatg
     8581 ttttgaattt ttttgtgatt tcttttcgca ccctcaatgt gatcttttcg cttaacgctg
     8641 ccattgtccg ttcctgaata aatgaagtga tgctgcttaa gactgaacag ccgatcagca
     8701 ataagacagg gaacaacaat gcttgtttga tatcactgaa agaaagctgt ccaatacctg
     8761 tttttcttat ttctgataag agatcatcga tcccgattcc catgatcaag ggcatggcta
     8821 cgactaatag gttcccgaat aaactgcata gaaacaatcc gtaaaaatat ttatgttcag
     8881 gtttgatcat tttccaaaaa cgtatcaaag cacgcgtgtt caacgttttt ttcttttcca
     8941 tcgtatccct tctttctata ttccttgtga ttttgcaaac tcctgataag tttggcaatt
     9001 agacagtagt tcttcatgag taccttgtcc aacgattttt ccttcatcta aaacaatgat
     9061 gttatctgct tgttggattg tactgaggcg ttgagcaaca atcacgagag ttttctccga
     9121 catgtgttta tgaagggctg ctcttaatgc tgcatctgtt ttatagtcta aagcggagaa
     9181 actatcatcg aatacataga tctctgctgg tttgatcaac gctcgagcaa tacatatccg
     9241 ctgtttctgg ccccctgaat aattagaacc gccttgagca acaaagctgt ccaatccgtc
     9301 aggaagggtg tccactagtt cttctaattg agcgatcttg atcgctttag acaactcttc
     9361 tgttgaggca tattcatttc ccatctgcaa gttgcttaaa attgtcccgc tgaataagaa
     9421 agccttctga gggacataac tgatgtggga gcggatctgt tcttgagtca tttgagtaag
     9481 aggaatacca ccaagggtta cttttcctat cgtagggtca ctaagtctca agagaagttt
     9541 cgccaaacta ctttttccag atccggtccc gccaacgatc gctgttgttt ttcctttagg
     9601 tattgtgaaa tcaatatctt ctagaactgg atcagagatt tcagtatatt taaatgtgac
     9661 atgttcaaaa gcagctgcat ttgtctgatc aaaggttggt tcagctactg ttttgatcgt
     9721 ctcttcctca atttcgatct ctgcttgcag tatttcttct atccgtcgta atgaggcaaa
     9781 cgatttaggg ataatgacca ataccatagc tgcgatcatc aagtaagcaa gtgtcagcat
     9841 agagtattcg actacagcag tcacgacacc gatttgtaat gctccttctg ctacaagatt
     9901 tccgccaaac cacaaaatag aagcataaac gattcccatg agcaaaaaag caattggagt
     9961 gacccaagca aatattcggt tcactttgat catttgatta gcatagtcag caaagctctt
    10021 attcgttcgc ttttcttcat atgattgatt atcaaaggca cggatcatat taatcccagt
    10081 aaagaattct ctcaatgtga tggtgatccg atccattttt ggctggatac tcaaagataa
    10141 aggtgcccct cgtttcatca gtcgataaac aatccataca taaaaaacaa cagagatcaa
    10201 tgtaacccat gttagtaata gagaataacg aaacatcatg agaatggtga aaacgcaaat
    10261 aaccggtgct ggtaagatca tttggcaaaa taaaacaatc atttgctgga cattatcgac
    10321 atcattcgtc attcttgtca aaagagatcc agaactaaaa cgactgatat ccttcattga
    10381 cagctgttgg aatttacgga aatatttctc ccgcgtttgg aatccaaacc tagcggaagc
    10441 caatgctgaa aagtaactag aggcaactgc agcgattgtt cctagaaacg ctacaagcag
    10501 catttcaact ccaatttttt ttataactga ggcttcgcca cttgctatac ctgtgtcgat
    10561 cagctttgct actaattttg gtacacctaa tgtaccggcg atttctaaac agatcatcac
    10621 aaaggtaagg agagcgagtc ctttgttttt ctgtaagaat gtttttaaga tagacatatt
    10681 attcctcctt ttttcctgat acttttcgat tctatacctt caagtaactt gaaggtcaat
    10741 agaaaaaaga ataaactgaa aaagaggtga gaaaaaatga aaaaaatgta tacgattggc
    10801 caagtatcgg aactatttga tttgccaaaa tcaacgatcc gctattggga tgaacaagga
    10861 ttaatccgtt caagtagaca agaagagaat gattatcgat tgtttgatat cgatgatatt
    10921 tttatgcttt atgatatcgt tttttataga aaattagata taccgatcaa acagatgaag
    10981 aatttatatg gaaaaacatt gacggagtta tatgagacac ttgatgaaac agaaagaaga
    11041 atccataaag aactggtggt gatgaaacaa aaacaaaaag agataaggga gcaaaaaaaa
    11101 cagttgaaat tgatgatcga tacaaacgag gaagaatttc ctgtagaaga gatccctttt
    11161 gactgtatga tctcaacgga gtttgaagat attgtggaaa tcaaaaaatt tctacctaac
    11221 tattcaagct ttgggatgat gagtatgcca gcttccagtt cacagacgat gtatggattt
    11281 tttatcgacc ctagtgaagt acatttattt actcaagacg tgatttggga gaaaaaagat
    11341 acggctgttt atcgtcgatt cttattgaaa tccgagatga accatgcgga acgtaataat
    11401 attttagaaa tcagagaaag aatgtatgaa aaaggatgga aaacaggaga agtgatcggc
    11461 cagtatctat tgacgaatac ggatgaaaac aatatcagaa ctgaatatta tcatgcatgg
    11521 atagaaatga aaaaatagga aatatgtgtt taagataact cgaaaatgat ggttgtttta
    11581 gttataaaga aaaattttct ggttcgatta cgggtttaat gtgggggatt attagtcgtg
    11641 gatagataga attttagttt tttagaggaa atatgtcttt aaaaatggaa tggttgcaat
    11701 tcttagcgat atatacgatg taattgtcct cttaaaaaag tatggaaaaa taattgtatt
    11761 gggtgttatg tataattcat ggtgaactga gactaatgag aagaaaaatt catattgtta
    11821 tgagtgagat tgtatcagat gagaatgata aattaaatag gtgcataaaa gcattacact
    11881 taaaatacat tgttgcttac attattacaa tatgttaata aggcaaaaat aaatagatgg
    11941 attgaataaa catatttttt aatcaaatag tccctactgt gactttcctc agctatcggt
    12001 gatactaccg atagcatttt tttgcttata aaataattat aagtat
//
LOCUS       DACCVZ010000085        11969 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.088, whole genome shotgun sequence.
ACCESSION   DACCVZ010000085 DACCVZ010000000
VERSION     DACCVZ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.088"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(143..1345)
                     /locus_tag="IVW63_002304"
     CDS             complement(143..1345)
                     /locus_tag="IVW63_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7860566.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(1348..1542)
                     /locus_tag="IVW63_002305"
     CDS             complement(1348..1542)
                     /locus_tag="IVW63_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP7860567.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(1589..2437)
                     /locus_tag="IVW63_002306"
     CDS             complement(1589..2437)
                     /locus_tag="IVW63_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HAP7860568.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(2642..2992)
                     /locus_tag="IVW63_002307"
     CDS             complement(2642..2992)
                     /locus_tag="IVW63_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860569.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            3587..4033
                     /locus_tag="IVW63_002308"
     CDS             3587..4033
                     /locus_tag="IVW63_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAP7860570.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            4657..5649
                     /locus_tag="IVW63_002309"
     CDS             4657..5649
                     /locus_tag="IVW63_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7860571.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            5665..6549
                     /locus_tag="IVW63_002310"
     CDS             5665..6549
                     /locus_tag="IVW63_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7860572.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            6598..8205
                     /locus_tag="IVW63_002311"
     CDS             6598..8205
                     /locus_tag="IVW63_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP7860573.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            8206..9690
                     /locus_tag="IVW63_002312"
     CDS             8206..9690
                     /locus_tag="IVW63_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAP7860574.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            9867..10859
                     /locus_tag="IVW63_002313"
     CDS             9867..10859
                     /locus_tag="IVW63_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7860575.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            10911..11780
                     /locus_tag="IVW63_002314"
     CDS             10911..11780
                     /locus_tag="IVW63_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP7860576.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
BASE COUNT         3720 a         1952 c         2473 g         3824 t
ORIGIN      
        1 ttgaaaaacg ttgatttatc ggcattcccc atccatatta tatttacgtc ttattcccac
       61 tcaatatgag tagcctcgta aagaagctat tatatcagtg ctttttcagc ctattcctca
      121 ttttggtagg gaaatggtag ggttagattt ttactgcttg atttccatta aagtttgcaa
      181 ctttagattt tgttgcacag gtaaatttaa tgtttcctgt catttgttct gcaattcctt
      241 catcattacg gctccataga tgagcgtagt gctttaaagt gatttcaggg ctagaatggc
      301 ctaaccgttg cgacacgacc agaatgtctg cgttaaactc attgattagg tagctaacat
      361 gagaatgacg taatcctttt ccttgtatta ggggtacctt agctagtttg gcataacgct
      421 gaataattcg ttgaacagtt gaacgataga gtgggaggtc agtgtagcta agaataaatt
      481 gttctacacc atgatttttt tgaataactt tccacttttt tagcacttca attgtatcat
      541 cgtccagaga aatgatccgc aagccgcttt cagtttttgt gtaaggtttc cgaataaaat
      601 ctttttgatt tgtcatttcc aaggtgtgat gaaccctcaa ctttttacgt ttgaagtcca
      661 cgtcattcca attaagtgct aatccttcgc ttacacgaac accagtcatg taatatagcc
      721 agatcattaa aaaacacata tgttcgtaga aatcatcttt ataaattttt gccaaaactt
      781 cttcaaattc ttcttttgtc cagtaaggaa cgattgattt tccttttgga attgcttttg
      841 ttcttttgga aatattctca ttcagaaatt gcagggtgac cgcatagtct aatgatttac
      901 gaaacatacc gtacataagt gaactgtatg cttgtgagta tccgctatcg ttcaataacc
      961 aaattcgata attttcacaa tctcgcacat tgatttcacg aagcttctta tcaccgaaaa
     1021 attcagtaat ctgaatcaat ccacactcac gagaactcca agtacttttt tgtacgctag
     1081 ctttgtagtg tggaacgtaa gactgctcca taaattcttt gtaagttaaa tcataattcg
     1141 caaatccatt tacaaccatg tattcatttt ttatacgcat gacttctttg tgtgcttcac
     1201 gagctgatga gaatcgtttt cctagagaat cttttgttcc tttcttctgg atcctctttc
     1261 cagtcacttg atctgttcct aactcaacta gataagaaaa gcgaccattt ttatcttgat
     1321 acacacaagg gtattttgtt ttcatagtta ttcctcctgt gaaagaggaa cacctataat
     1381 ttcttcaatt acttgtcggg gtactacccc aactctttta ttattataat atggatatcc
     1441 ctgatttacc attcttgttt ttgcttgtcg gattattgtg gtagcttgat gtgttttaaa
     1501 tcctagagcc tctaaatctt ttcgacaaat tgtatttttc attgtataaa ctcactttca
     1561 aagaaaacac tatcattggg taatagtgtt atttctttat ttttgtataa tgaacggtac
     1621 tttcttgaaa atccatcact tgttcaggac ttcccaactc atttaaagct aaagcattgt
     1681 aaaaaaatgg acgtctaact atatattcgc ttgtatatag tatatcttga ttcgtggaat
     1741 catagggttt ctttaccatc tttttggtga cagttggtag tttgagattc cgggacttga
     1801 aaaaagcttt tttcttatgc tctttcaatt ccagctcttt atcgaaatat ttgctgatat
     1861 agcgcccgcg attttcgata ctgtctacat cgatcttgtt gatcttaacg aaaccctgac
     1921 cccaaatcgt agttaaccgg ttaaatgaga taaaggggaa atcaaacaag ataatatggt
     1981 agtggattgc accgcgttgc tgcttttccc acgtggcgag atactttaaa tttgcttttt
     2041 tagttttata gaggtcataa ttcagtcgtt tgataaattt tttaaattca ttatttgcat
     2101 actcaatgtc ttgaatgttt tctttgaaag tgagagttaa aaatttcgtt tgattgtcaa
     2161 aattcgtgtc tacaaggcgg gcaatctcaa atcgcatact ttgataatgt ttctgtttgc
     2221 gttttaaact gtcatattgt ccttgagcgg ataattcatc atagtttttt cttttttcaa
     2281 gagtaatatc attttcataa atccaagcta atttttgttt tcgttccaga tttacttcgt
     2341 tttcgatcgt tttacgtttg ggagtaatga ttgcttcata atcataaatt tcaatatacg
     2401 tgggagtttc aatgattttc tgattataag cttgcaaaaa tcatcactcc ttgttgcgta
     2461 ttcgattgtc aaagaaccag tcattttctc ctgatgttga tctataaatc aagttaaggg
     2521 ggaaggcctg cgtagcagcc cttctagcct atggggtgtt gggcggtctt aacggacaga
     2581 aacggctctg tgggcgctgc cccgccgttt cgtcctaacc acccaacact ccatagtata
     2641 gttagttttg tgtagtggta ccttgttttc tgggaatcaa agttgccgta tcagcggttg
     2701 ccgataaccc ataactgaca aattgtccat tcgagcgtcc ccaaggtaca atcaccaaat
     2761 tggtaaatgt aattatggct aaaccttgtt gggtaagttc ttccggcgtg atcacaggat
     2821 gttcagattt gactttgaca ctgatttttt cgtagcgaag ttttggtagg atacattcgt
     2881 agctccaacc tagaatttcg ccctcctttt gccagcgagt gacattgacg acttggtatt
     2941 ctttttcgag tgtttctttt ggtaaactga gatcggtaat ttttattggc atcacaattc
     3001 tcctttttta tacgaaagtt tatacgattt gattaaaaaa tatagatggc catctacgac
     3061 ttgtattata tacgagaact tatacgtagt caagagattt tctaaaaaaa tatatacgat
     3121 tttttatacg agtgttataa tgaaaaaaat gataaggagg aatttgaata tgtttggttt
     3181 agtacaacct aataaagtga aggtgggcca acgaatcaaa gaaataaaag acggaatgtc
     3241 tctctctttt acagaattag ggaatcgatt aggtttaaaa aagccgacga tcagttccta
     3301 cgttcaaggc tatgcgttgg ctcctaagag tgtgatcaac caattatcta gtatcagcgg
     3361 aaaacctgtc ggctggtttt attttgggca tgtggaagaa tatatccgag agtatttgtt
     3421 tctcattggt cagaaaaaaa tagtggacga ttatcctgaa atcattgaga aaataaagca
     3481 agaattttat acgggcgagt tcaaaaatcc tgcttgggag aatgagctag gctatccttt
     3541 ggaggaattt atccaagaat gttttgtaga atattcgagt gaaatcatga aggactatgt
     3601 cgtacagatt acgaaagagg tacttgaaga atccaaaacg ctaaacaaac tatcatcaaa
     3661 agcaaaagaa gaagctgtca cgattctttc atctgggatc attgactata tcgagatgag
     3721 tggtgagatc aagtatggag agaaagatcg cattgcgaaa atggtgaaag aatcaataaa
     3781 aacctttgat gtgaaacaag acctgacatt taatgattcc tatttgattg gaaagttgat
     3841 caatattctt ggtacagatg aagatacgga gctgtttctt tcttctttat caatgatatt
     3901 tactgataag catttttcca ctcgatttgg tggggaagaa ttagtcgaaa tatttcaatc
     3961 gatgcgacca gcgttaatca aactctatcg ggagaaaaca ccagatgaat tttatgattg
     4021 gtttgagaag taaaataaga aaagtggctt agattacaag ttggtgaaaa aatttttttc
     4081 agcataacat cagtaatcta taaaggggtt gttgattata ctgtagaagt taagtactca
     4141 agagattttt tgtacgtaaa caaagcaaaa aagggtgcag tttcactaga aaatgtactc
     4201 ttttttgtga tttttcttag ttatagagtt tttttgaaac tttaaaaatg agaaaacata
     4261 ttgattttaa agagtgtaga catagcttct tttgctaaat agattaaact tactggtgag
     4321 tggtcttgaa catactttta aatcacattt tactgagttt tattggattt tataattcat
     4381 tggaaacctc gtacttaatc tgtttttatc tatcgactag aatctgtata tattccagct
     4441 atcaatgagg ccgcagaaaa gggtgcttaa aaataatctg ttgtttaaaa tattattatc
     4501 agaatactta gatacaaaat tctggcacaa agtaaaaaaa atattgactt aaaaaaatgg
     4561 atatggtaat ctataaacga aaatagtggt aacgtttcca aaatgcatct tcgttaaatt
     4621 tttatttttt taaacgaaaa tggaaacgtt tctaaaatgt attgggagga gattgaattg
     4681 gaaaagacat tgggaccagg tggtgagata agggcggtac aacgggataa aaaaaatatt
     4741 tcgaagtggg aaaaattaaa gaaacagttg cggcgtgata agtggatgta cttgttgctc
     4801 ttaccaggta tcatcatgac gtttatcttt aagtatgtgc caatgtacgg tgctgtgatt
     4861 gcatttaaag actataatcc tatgctagga attttggaaa gtccttgggt aggactagat
     4921 cactttaggg aatttatcag ttcaccaaat tttacgcttt tgctgagcaa cacattaaaa
     4981 attagtattt atggtttatt gttaggtttt tttccaccaa ttattttagc actgagcttg
     5041 aatcaaatta tcaataaaaa aataaaacag aaaatccagt tgattctata tgcgccgaat
     5101 tttatctcag tagttattat tgtggggatg ctgtttttgt tcctatccgc aaatggacct
     5161 attaatgggt tagtagaaaa ggttacgggg caaccaatta tgttcatgtc taatccagct
     5221 tatttcagaa cgatttatat tttatcggga atttggcaag gaatcggctg gtcatccatt
     5281 ctttacaccg caacgctggc gggagtcagt accgatttat atgaggcagc aaatatcgat
     5341 ggggcaaata ttttacaaaa gatttggcat atcgatttgc ctgcattgag gcctgtgatg
     5401 gtgatcagct tcatcttggc cgccggcggt attatgaatg taggatatga aaaagcctac
     5461 ttgatgcaaa cttcaatgaa catccctgcc tcagaaatca tttccactta tgtatacaaa
     5521 gtcggcttgc aatcaggtga ttatgcctac tctgctgctg ttggtctgtt caatatgatt
     5581 attaatgtcg ttttattact gattgtcaac aatataacca agcggctaaa cgatggtcaa
     5641 ggcttgtaat gaaaggagaa aattatgaat agtgctttat caaaaatcga ccgtcaaatc
     5701 ttatggttga atcgagtgat tgtaactttt ttagtcgtca tcaccattgt tccgctgatt
     5761 tatgtactgg tagcttcttt tatggaccca gctactttga tcaataaagg tataagcttc
     5821 aatccgaaag attggacaat acagggatat caacgggtat ttgcagatga ttccatttta
     5881 cgcggttttg taaattcgtt gttttactct tttagcttca gcttattgac tgtatttatt
     5941 acgatgatca ctgcgtatcc tttgtctcga cctaacttgg cggggaaaaa gattattatg
     6001 actttttttg tcattacaat gttcgtgggt ggtggcttga tacctaccta tttattggta
     6061 aagaacttgg gcatgttaga tagtgtatgg gcgattatcg taccaggtgc tataaatgtg
     6121 tggaatatta tcttagcccg tacctatttt agtgctttgc caaaagaact ttctgaagct
     6181 gctactatcg atggcgccaa tgacttgcaa atactgttca aagtcatgct tccattagcg
     6241 aaaccaatta tgttcgtatt gtttttatat gcctttgttg ggcaatggaa ctcatacttt
     6301 gatgccatga tttacatcaa agatcccgac ttacagccgt tgcaactcgt attaagaaat
     6361 attttgatcc aaaaccaacc ttcacaagac atggtgggag ccaatactgc catggcagaa
     6421 atgaaacaaa ttgctgagtt gatcaaatac gcaacgatcg tcatttctag tctgccatta
     6481 atcataatgt atcctttctt ccaaaaatat tttgataaag gtgttttagt tggttctgtt
     6541 aaagggtaag tattgttcac tatttgtatg aataaaaatt ataaaggaga ttttaagatg
     6601 aaagcaaaat ggatgctgcc aatcgttttt acttccgtac taattttggg ggcttgtgga
     6661 ggctcaaaag aaaagagtaa atcaagccct gattatgaac tagaaaatgt ctcttttcca
     6721 ttgaaagaaa aagtatcttt aaaaatgatg tctcaaagtg cccctttggc tcccaatgat
     6781 cctaatgaca aattgatttt ccaacgatta gaagaagaga ccaatctcca tattgattgg
     6841 acaaactaca gtagtgattt tgccgaaaaa agaaatttgg atatcgctag tggtgattta
     6901 ccagatgcca tcttcaacgc cgctgcaggt gactatgatt tattaaactg ggcggaaagt
     6961 ggcgttattg taccgattga agatttgatc gaagattata tgccaaatct gaagaaaatt
     7021 tttgatgaaa accccgaata ccgacaaatg tctactgcac ctgatggtca catttactct
     7081 atgccttgga ttgaagaatt aggcgaagga aaagagtcga ttcatacagt aaatgggatg
     7141 gcttggatca acaaggagtg gttggataat ttgggtcttg aaatgccgca aaccactgat
     7201 cagttgatga ctgtgttgga ggctttcaag acgcaagatc caaatggtaa tggtgaagca
     7261 gatgaaattc cttttagctt tattaacaat ggaggaaacg aagacttaaa atttttaatg
     7321 ggggcattcg gtctaggtga taatgatgac cacttagtcg ttgataacga tggtcaggta
     7381 caatttactg ctaacaaaga agggtataaa gaagccatca aatatttcaa tgaaatgaat
     7441 aataaaggtc ttattgataa agaggctttc gaacaagatt ggaatacgta tgttgccaaa
     7501 gggaaagaac ataagtatgg cgtgtacttt acttgggata aagcaaatat cacgggtgca
     7561 gatgatagtt atgacgtctt gccagtctta gcgggaccag atggaacgaa acatgttact
     7621 cgtacgaatg gcatgggttt ctcaagagat cgtttcgtaa ttactagtgc gaataaaaac
     7681 ttggaactta cagctaggtg gatagataaa atgtatgaac cgttacagtc tgtccaaaat
     7741 aactggggaa cctacggtga tgaagcacag gcgaatattt ttgaattaaa ggatggtatg
     7801 ttaaaacatt tgcctttaga ggggacagca ccgggggaac taagacaaaa aaccgaagct
     7861 ggaggaccat tagcagttct tgattcttat tacggcacag tcactactat gccagatgat
     7921 gcgaagtggc gtttagattt gatgcatgac acgtatttgc catatattac agaagacaat
     7981 atctatccac gtgtcttttt agaaaaagaa gaaacagatc gattagcaaa aatcgaaacg
     8041 gatatgtggg attacatcta tcgcaaaaga gcagagtgga tcaccggcgg taaaatcgat
     8101 gaagaatggg aagaatacct tgctgaattg gaacgtgtag gtttggaaga atggattcaa
     8161 ataaaacaaa ctggctatga taattttttg aagggagcac aataagtgtt agtagaagaa
     8221 acggcgattt tggataaagc aaatcgattt attgaaatga tgcgaggaaa agttaaccct
     8281 cagtatcgac aaaactatca tttttccgca cccatcgggt ggataaatga ccccaatggg
     8341 tttatatatt acaaagggca ttaccatctc ttctatcaat actatcctta cgatagtcga
     8401 tgggggccca tgcattgggg gcatgcgcgc agtagtgatt tggtccattg ggaagatcta
     8461 ccagtagcgt tagccccaga tcaaccttat gacagcggcg ggtgtttctc aggaagtgca
     8521 attgaaagag acggaaaact atatttattt tatacaggct gtcaagaaat tgatggtatt
     8581 agccatcagc atcaatgttt ggcggtctct gaagatggta ttcattttag caaatacagt
     8641 ggtaatcctg tggtagcaga aaaacagcta ggtgaaaatg ggctaataca agaatttcgt
     8701 gatcctaaag taattgttca caacgatggt tactatatgg tagtagctac taaatctaca
     8761 cagtctactg gtagaatagt gatgtttcaa tcgtcagatt tgtatacttg gcacttttac
     8821 tctgtgctgc tagaagggac ttcagagcaa ggaataatgt gggaatgtcc tgatttattc
     8881 catttagacg gacgagatgt cttaatcatg tctccgatac aaatcaagaa gaacggactg
     8941 gaatatcata atatcagttc taccatggct tgtattggtg aggtaaactg ggaaacaggt
     9001 cagatgatag ttgataattt ccatgaaatg gattttggaa tggattttta tgcaccacaa
     9061 acaacaagag atcctaatgg tggacgggtg atgattgctt ggatgcagat gtgggatcgt
     9121 acattgccta cacatgagtt aggccatctt tgggcaggct ctatgagttt gccccgagag
     9181 ttaagagtga aaaaaaatcg attggtacaa aaacccatct caactgtata tagtcattta
     9241 gtttatcaac aaggcagtga aaatattgca gtgactgaca catcagtcgt atttcgaaac
     9301 gcgctgtctg attcttcata tttacatcta gtcgcagatt tggagaaagc tgaagttttt
     9361 acaattgaat tactgcggtc taagacggat tgtctcaaac tagcctatga cactgctaca
     9421 caggtttttg aattggatcg tcagaaacta ggaagagagc ttacaggggc ggaagaagac
     9481 cctctgaatg tacgaaaagt tgaagtacct ttgattgata atcagctcgt tcttgagatt
     9541 tttagagata cctcatcaat tgaagtcttt attaatgggt tagaagttat gacggctact
     9601 ttctatgagc tggaaaaagc tcgagatatc ttgtttcatt cgatcggaga aagtcgtatt
     9661 caagcttttg aaacagcgag tgtgaaataa atgtttgatt gcttaggcga tgaatcaatt
     9721 atttaatagg ttttgaagga taatgttttt agaaaagaac agatagctag atttcccatg
     9781 gatttgctat tagtattttg aaaaaattag taatttatga caaaattcat tatactaaac
     9841 ttgtgcagaa atgtgaggga tcaactatga aagcaacaat gaaagatgtc gcaaaattag
     9901 caggtgttgg agtaggaact gtttcccggg tattgaataa cggttctgtt aaagcttcta
     9961 ctagagaaaa agttgaagca gcaatgacag agttaaacta tcaaccagat ttttatgccc
    10021 gggggttaaa gatgaagcat acgaacacgg ttgctttgat tctacccacg gtatggcatc
    10081 cattttttgg cgaatttgcc taccatgtag aaacagcatt agaaagacaa aactacaagc
    10141 tttatttgtg taactccagt ggtaatagtg aaaaagaaca agaatatatc cagatggtca
    10201 gccaaaataa agtagacggc atcattggaa ttacttattc agatatcgat gaatacattt
    10261 cgagtaatct gccttttgtt agtattgacc gttatttcac tgaagaggtg atttatgtga
    10321 ccgctgacaa tgcggccggt ggacgtttgg ctgcaaatga actttatcgc cgaggatgtc
    10381 agaatgtagc atatatcggt gggtaccaag aaacaccgaa tgaaacgaag agtcgtcgaa
    10441 aatattttga aatcgagtgc cgtcaactgg ggatttccta taaagcgtta gatatgttag
    10501 aacctttaga ccatctctca gaacgtgtaa caaatttttt gttagagaat cccgatatcg
    10561 atgggatttt tacgatcaac gatccaatgg cattagctgt cattgatatg cttgaaaaaa
    10621 tagggaaaaa cgtaccagag gatgtccaag ttatcggatt tgatggtcaa aagatgacag
    10681 aaggagatcc ttatctagtc tcaacgattg cccaacctac aaagcaaatg gcggaagtgg
    10741 cagtggcaaa attaattgct gtcattaatg gagagacagt agaaaaacgt accgtattgc
    10801 cgattgaatt tggcgaaggt gacacaacga aacctttagt gagaaacgat tttgcttagt
    10861 gcaaatacgt ttcttttttt gaaaatgagt gaatgaaagg tgtagataaa atgttatatg
    10921 gtggaataga agccggtgga acaaagtttg tctgtgggat tggtaatgaa caattacaag
    10981 tgatagaacg gaaaagtttt cctaccacaa caccagaaga aacgatggag caagtgtttg
    11041 atttctttga taagtacaaa ggaaatatcg catcaattgg tgtaggagca tttgggccta
    11101 ttgatattca aatcgaatca agaacttacg gatatatcac caacacaccg aagttagctt
    11161 ggcaaaatta tcattttgta ggagctttgg aaaacgcctt gtcggttccc atctattgga
    11221 ctaccgatgt aaatgctgct tgttatggag aatatatggc agggtatgga aaaggtaaaa
    11281 atagtgttct gtattacacc gttggtacag gtgttggtgg tggtgctgta gtggatggga
    11341 aaatagtcgc aggttttagt catcctgaaa tgggacatat gctcttacaa cgtcataatg
    11401 aagatcaatt tgaaggaatc tgtccttttc atcatgattg tttggaaggg ttagcatcag
    11461 gacctgcgat tgaaaaacgc tttggaagaa aagcccagac tatctcattt gatcatcctt
    11521 attggacgat tgaggcagat tatcttgctc agtgtgtgta taacacaacg ttactatatg
    11581 caccggaagt aataatttta ggcgggggtg taatgaaaca gccgcaacta ctcgagttga
    11641 ttcgccaatc gtttaaagaa aaaatgggtt cctacgtgga tacgcctact ctcgaagaat
    11701 atctactaac tccaaggctt gctgacaatg cgggcttgat tggctgccta gctttagcaa
    11761 taaagaaact caatcattag aatagtattt attagaacta ttcataacat accggaagtt
    11821 taaaagggta ttctgaaact taaatagtct caattcattc ttctttcttg agaatctgag
    11881 tagagacttt tattctgttt caaattaata taattacgaa atgatattga gtacaagaaa
    11941 gttcttttta ccagatcttt taaatcgaa
//
LOCUS       DACCVZ010000086        11834 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.089, whole genome shotgun sequence.
ACCESSION   DACCVZ010000086 DACCVZ010000000
VERSION     DACCVZ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11834
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.089"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(19..225)
                     /locus_tag="IVW63_002315"
     CDS             complement(19..225)
                     /locus_tag="IVW63_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860577.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(241..855)
                     /locus_tag="IVW63_002316"
     CDS             complement(241..855)
                     /locus_tag="IVW63_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAP7860578.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(1002..1685)
                     /locus_tag="IVW63_002317"
     CDS             complement(1002..1685)
                     /locus_tag="IVW63_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAP7860579.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(1794..2252)
                     /locus_tag="IVW63_002318"
     CDS             complement(1794..2252)
                     /locus_tag="IVW63_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAP7860580.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(2336..4099)
                     /locus_tag="IVW63_002319"
     CDS             complement(2336..4099)
                     /locus_tag="IVW63_002319"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAP7860581.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(4320..5780)
                     /locus_tag="IVW63_002320"
     CDS             complement(4320..5780)
                     /locus_tag="IVW63_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860582.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(5988..6914)
                     /gene="glsA"
                     /locus_tag="IVW63_002321"
     CDS             complement(5988..6914)
                     /gene="glsA"
                     /locus_tag="IVW63_002321"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAP7860583.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(6937..8364)
                     /locus_tag="IVW63_002322"
     CDS             complement(6937..8364)
                     /locus_tag="IVW63_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7860584.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(8395..9609)
                     /locus_tag="IVW63_002323"
     CDS             complement(8395..9609)
                     /locus_tag="IVW63_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAP7860585.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(9950..10192)
                     /locus_tag="IVW63_002324"
     CDS             complement(9950..10192)
                     /locus_tag="IVW63_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP7860586.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(10224..10781)
                     /locus_tag="IVW63_002325"
     CDS             complement(10224..10781)
                     /locus_tag="IVW63_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP7860587.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(10794..10982)
                     /locus_tag="IVW63_002326"
     CDS             complement(10794..10982)
                     /locus_tag="IVW63_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAP7860588.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(10995..11561)
                     /gene="amaP"
                     /locus_tag="IVW63_002327"
     CDS             complement(10995..11561)
                     /gene="amaP"
                     /locus_tag="IVW63_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAP7860589.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         3472 a         2449 c         1936 g         3977 t
ORIGIN      
        1 acttttcgga ataaatattt atttgttaaa gtaattaaac aatccgctaa tcgtttgatc
       61 tggcatttct atttccttac catctaaagt aacagtagta acgacaaaat ggtcttgcaa
      121 tggcggaact tctaagtact gcccttgcag aaaatcattc actgtttcat attctttttt
      181 catttctttt gaatctgtcg atggtttata gcttattttt aacataacta gtgctccttt
      241 ttattcggga cgtgcaatcg tgaaaatttc tcctattgct gcataatcat ttcctgccaa
      301 acggcttaca gcattcaatt ttcttggatc gatccttcct gtcttatcat catagactgt
      361 ttcatttaaa tgatatttct gtacttctag caaaaataaa tcagctgtta ctttattttt
      421 attccgtatc tcgacatgtt catataagga tgtttcaaaa cgaacttttg cttctgtcaa
      481 tgctggtact gaaatgatta ctgaatcagt taaagtcaag tcagtcaggt acagttcgct
      541 ttcctcatta ggcagattgg ctgctgtttt atttacttct tctacgttgt cctcatcaag
      601 gatatggata acagcttctc ttgtctcaag aatattcttt gctgtgtctt ttactgcatc
      661 ttgttttctc tggatcgcca aggataagat gggtcgattc gaactgacga tattgaagta
      721 actgaagggt gcgatattca ctatatcttt tgctgattta gtcgttacta ctgctactgg
      781 tctagggatg actgaaccaa tcagcaactt gtaattttca cgttctgtca attctgaagg
      841 actccgttca aacatggttt cgccttcttt ctataaaatt cgttaaaaag cagatcttga
      901 agacaaaatg aaaagtaatg cttttttcat cttcttagaa tctgctttaa actatctatc
      961 aatttttctt ttttgtcaag aatctgtgcc gtgcgtgttt tttagttatt tgctttactt
     1021 gcggcttcga catatctttt agtgatcaat tgcggacggg tgataataga tccaactacg
     1081 actgaaaaag cacctaattc atatgctttc tctacttgtt caggagagtc agtatgtcct
     1141 tccataatta ctgggatatc gacttgttct atgatttgat tcaataaatc aaaatcaggt
     1201 gtctgcgtct ttcgtgaata ttctgtatag cctgctaaag tcgtagacaa aagatcaaaa
     1261 ccatcttctt gcgcttgaag cgcttcctca aaagtcgaaa tatctgccat agctaaccga
     1321 ccgtgttcgt gaatcatttg gacaagttca gcagttgttt tttctgtcgg acgtttacga
     1381 gaagttgcat ccagtgcaat gatttctgct tgcgtctcca aaagttcttc cacttctttt
     1441 tctgtcgcag taataaacac ttctgaccca tcgtaatctc ttttgataat ccctattacc
     1501 ggtaaatcaa cgattcgctt gatttcattg atatcttctg tcgtatttgc tcgaatacca
     1561 actgctccgc cttcttttgc agccaaagcc attctcccca taataaaaga actgtgtagc
     1621 ggctcgtttt ccaaagcttg acaagaaacg acgactccgc ctttgatttg ttccagtgta
     1681 tccacaatat ctcctccagt aatgttatat aaaaatacag cttcatataa aaatgtaacc
     1741 cttttctatt caggagacaa taatgagcta tttctttcag cagacctttc ttactaaaag
     1801 aaaattactt caaattcttc gtatacgacc agcttctctt ctgtaaattc tatgttcaac
     1861 gcttctttat aagcatgttt aaaaaactca gcatggactt tccgccaata agctaatgtc
     1921 cgatcccctt ctccttcttt ccaagcatgc tctttcgtga cttcactaaa aggcaagatg
     1981 gtcacattta tatttttgat gatacaaact ggttcatttt ttccattcag gaccacgtct
     2041 aattgaccaa cttttggtaa aggctcattc tcttgtttat acagatcgta accacttgat
     2101 gtaccagtct ttatcttttt tacaactagt tcgctcaact cgtctgccat tttttctgta
     2161 tccccaaatg aaaagaaacc taatttttct gattgataac taggatattt ttcttggaac
     2221 tttttgacat attcttctac ttgctgatac ataacatcca cccctttgct ttttataatg
     2281 aaaaaaccat ccagatacta gtataaacaa ttatctggat ggtgagcata atgaattatt
     2341 gaatattcaa gacacgcaga ctatcttcaa cgatttgttt tggtgttaaa tgataacgtt
     2401 cataaagctg ccctacagga acgctatccg tgaattcttt ctctgcacca aaatttaata
     2461 cgttcattga agaatcacca taataacgac tgatattttc gccaaatcct cctgacaaac
     2521 taccatcttc taatgtgatg actaattcgt gtgtttcttt taatttatct aatgtttcta
     2581 cgtcattttc tgtgatcgtt cctggattga tcaacgttgc ttcgattcct ttttttctaa
     2641 aagcttttac tgtttctttt cctaattcaa gaaaaccgcc taaagctaaa attgctactt
     2701 ttcctccatt atttactgtt tgataggctg gaatactata atcatttgcg atagctgtac
     2761 catgttctac accatgtgta ggaattcgga ttgctacagg ctgcgctgtt tgttcgaacg
     2821 cccaatctag catagagatc atatcctctt ttgttgctgg agcaagatat ttgatgttcg
     2881 ggatacttga taagtaagga atgtcaaatg ttccttggtg tgttcggtca ctagctgaga
     2941 tcgttccgcc accgactaaa ataatcactg gattctcgtt gatcgctaaa tcatgtgata
     3001 attgatcata tgcccgttgc aagaaagtac ttgattggaa gacgactgga cgtactccct
     3061 gagaagccaa agcagaagcg aaagtgatag agtgctgttc agcgatcccc acgtcaaaat
     3121 aatgatctgg atgtttttct tggaatgttt tcagtccaaa ggcgcctggt atcgctgcat
     3181 tgactgcggc aataggagct gtacttgttt gcattttctt atccaaataa tccatgatga
     3241 tcatattaaa tgtttctcca gaagttactt gctttgcctc cccggtggac agatcaaatg
     3301 gtacatgcca atgatatttc attttattat cgattgccgg ctgataaccg cgaccttttt
     3361 ccgtatggac gtgaagtaca atcggatgat caatatcttt tacttcttca aataaacgga
     3421 tcaccgtttc cagatcgttt ccattatcca cgtaacgata atcaaatccc attgctttaa
     3481 ataggttatt gctgctttta ccgttggttt gacgaagctc agctaagttt ttatataaac
     3541 tgccatgatt ctcatcaata gacatctcat tatcgtttac taatacgatt agattggatt
     3601 gtaaaacacc accattgttc aatccttcaa aagctaagcc accacttagg gagccgtcac
     3661 cgataaatgc taccacattt cctgattctt tcttcagatc tctcgcttta gctaaacctg
     3721 ttgctaagct gatagatgta gatgtgtgcc ccactgtaaa atagtcatgt ttactttcat
     3781 gttggttgga atatccgctc acttcacggt aatgtccttt ttcaaaacca ttttttcgac
     3841 cagttaaaag cttatgacca taagactgat gggaaacatc ccaaacgatt ttatcctttg
     3901 gtgaatcaaa tacataatga aacgcaatcg ttaattctac tacacctaga ttcggaccaa
     3961 cgtgcccacc tacatcgctg tccttttgca agattttttg gcgcatctct tctgccaact
     4021 gtttcatttc ctcaacagat aattttttga catctgcggg gctattgatt gcatccaata
     4081 catgtaatac tgtactcata atacattctc tcctccgtac tatcttcttt taatgaaaat
     4141 agatttgtta cactttatct attctactac ttagagttga ctctaagtca atagcatttt
     4201 aaaaaaattt cagagaaagc ttgttatata agtagatctt cgcacgaatc aggactcaaa
     4261 taaaaacctt ctacagacaa ttaaaaagct ttgtagaagg tctcctaatt aaggtctcat
     4321 caagaaatat gtttttttaa taggtgaagt tcctgagcaa tatgatacaa atggatgttt
     4381 gcacctttta atgagattgg atagatcttt gtcttttcag tttctaatcc attttgatag
     4441 ctagcagcat cgcacaaaac cactcttttt ttcgcacata gacattcatc aggcaattct
     4501 tctaatgaac gaaataaaat aggatttatt tcagcgatgc cttcttccgc atacaaatga
     4561 aattgggttc gataaaaaaa ttgtttgact gaactttctg aaacaacaaa aatttctatt
     4621 tcctgtctcc ccgcttgttc actgttgatc aaagaaagac ttttgacgaa ttttcgaatg
     4681 aaattttcat tccatcttag ttggatttga tttttctttt tccactcttc caatatttct
     4741 acaatttttc cgtacagaag ttgttctttt tctgatagaa gatagatcct ttccggtaaa
     4801 aatacttgtc catctgccca caacgtacgg acaaattgta aaaaggattg cttgaaaata
     4861 aaattttctg catcgtcgat ttcagcgata ctaataatct gtaaaatcaa ttcattcagt
     4921 gataggtcat tgagaacaaa atttttataa acaacttcga aatcttttct taacagctcc
     4981 atgttctcat tggtataatt tctactgttg aacaaagaaa aaatataata gacatcttct
     5041 tcttgtaagt ctagaattcc tttttgctct tccaatcctt gacagactaa ttgaaataac
     5101 ggcttcgttt ctgcgctttt cttatcttct tctttcagtc caaggggaaa tgcctttctt
     5161 ccgattgcga tctctattcc tcgtatgata aaggactttt catcttccga atatcttctt
     5221 ttaaaaaaat gagtctctac ataatcaatc aactcgttac aagcttcttc tacatacgga
     5281 tttttatttt catagccttc ccaattgaca taacgtacta aagctagcaa gatgttccgc
     5341 gagtcaaatt ctgggataat gatttcttta tttttcaaat aatcattttc tttaaaaaaa
     5401 tccaatacga tttttttgat tgtatatact ttgctcaaag aaataaattc aagatcagcc
     5461 agttctgtac tcgtgaatat accattaaaa taataactta aaaactttaa aaaataagat
     5521 tgaccgtaca gaaactgtgt gagctcagaa agagcaatac catgtttgaa tacgagttta
     5581 tacttatgct tctctcttac ttgttctttt atacaatatt ctagacactc ggctagactt
     5641 tctagatcgt gaaggatcgt tggtgtagtc acccttagag aaatagctgt ttgttcgatg
     5701 tctatttctt ggaattcaaa taattgttca cacagataca cttttctaaa tatatttcgc
     5761 tcgatgtaat tttccagcat tcctgataca cgcctccagt ttttcttatg attttattta
     5821 atcatatctg taaatcgtat ttttgtttcc tttttattta gaaaagccct ttcaaaaacc
     5881 aataaaaaaa gaaactggga caaaagtcaa acaagctcac aatttcagcc tcattgtagg
     5941 tagctttgag ccgtttggac ttttacccca gcctctttca agaatggtta ttcaaagatg
     6001 tcagcgtcta gttctttgac tacatctttc aacaattgga taccagctgc gctgttacca
     6061 aatggatcta gtgccgggct gaagacacct atgccgtaac gatttggcac agctgccatc
     6121 aacccgccgc ctacaccgct ttttgcaggt acaccaacat ggacggaaaa ctctcctgat
     6181 tcatcataca aaccagcagt tgtcataatt gatttgacga ttgtagcact ttcttcagta
     6241 atgatttgtt tgccattcca aggagcaatt cctttatttg ccagcacagc agctaatttt
     6301 gctatgcctg tagcggtgac attgagggag cattgtctga aataagcatc gagtatctcc
     6361 ggtacgtctc cttcgatcat ttgattacct ttcatatagt aagcaagaga gcgattgata
     6421 tcacctgttc ttgattcaga atgatagatt tcttcattca atgtgatatt aggatcatca
     6481 cagatctctt tcataaatga caagattcgc tcaaattttt catctgcatc tttaccggca
     6541 atcaacgagg ttgttgcaat cgctcctgca ttaacaaaag gattcattgg atgtttgcga
     6601 tgattgattt ccatattcat gatagaattg aaggcaaaac cggttggttc cgtgttgatt
     6661 gtttgaaaga ctttttctat tccgttgtct ttgattgcta ataacaatac gggaactttt
     6721 gacatgcttt cgatggcaaa gcgcacatcg gcgtctcctc cctcaatcag ttgttttgta
     6781 tccaaatcat aaatcgccat acctaattgt ttgggatcca cttcagctaa tgctggaatg
     6841 taatccgcca cttgtcctgt ttgataatag tggaaatttt ttccaatcaa ttgttctaat
     6901 tcttttactt ccatttgaat aaccagcttt cattttttat ttttctgcat gctggaattt
     6961 atgacggcat gcgtagatcg taaatggaat aactaagacg ataagataag aaacaatcag
     7021 aatcgtttca taaatcccat gctgtccagc tgcgatacta gcaggtggaa caaatgagat
     7081 acaaaaagca aaaagtgaag tcaaaagacc taaacaagca acgattactt ttacaacttt
     7141 tccgcctgga acctgatagg ctctttcaag actgtcatct ttaaaaacca gcttcaaata
     7201 gcccgcgaaa aacataaagt acaacatcag gtagattaca acagtcaatg acatcgctgc
     7261 aagaaatgaa agattattcc ccccgccgct taatgtaaag acggctgccc agattgttgc
     7321 aacgatccca tttgcgatca tcaaatgagc aggaacaccg tgtgtgtttt cttttgcaaa
     7381 atattcagga agtaatcctt cttctgctgc tacgtgaagt gcttttgaag gagaggttac
     7441 ccaagaagca atttctccga tgacacctaa acaaacaaga atcgcaagaa ttttcgcaat
     7501 ccatgcaaga tttggatcaa tgtgtcttaa taggaattct aacgattgaa tcacccctgt
     7561 attaagagac aaaccatgtt gaggtactgt agtagcgacg gtcaatccgc caaaagtatc
     7621 taaaatgatt gccagaataa ccaatacaaa cattgctaat ggataatcct ttttagggtt
     7681 ttccatttca tttgcatgac tggcagatgt ttctacgccc atatatgcta aaataaagga
     7741 aacaaaaaca accagcgtag gcaatttcga aaaatcagga atcaatgttt tcatagacag
     7801 tatcgtttgt agtggagcgc ctgaagcgac ataatggatc cctaagccaa acaagactaa
     7861 tgctggcaac aagataccag ctacaaaacc gatccgagca atcaatgaag tgtatttggt
     7921 tccttttaac tgtgagagta aaatagccca gaaaataatc aataggattg ccaatttcag
     7981 atatttattg ttttgtatag caccaatacc cgttgcatag gataatgcac cagttaagaa
     8041 atacagcatg gtcaagtagc caactgttat ctcaaaccat tggaaaaaga ttgcggcaaa
     8101 accgaatcgt tttcccaatg tgcgactgac ccaagtatag acaccgcctt tttcccatcc
     8161 tttcaccgtt gccatctctg ctgcgcacaa tgccacaggg ataaaccata gcaaaccgcc
     8221 taataacaag aaaaatacta agctgaagcc tgaggtcgcg aatgtgggat attcatataa
     8281 tgaaacgacc attgagatgg tcatagccaa aaagccaaag aacgttaatt tttttgcagg
     8341 aattttcgtt ttgctttgtt gcatgaatct tcctcttttc tatttgaatt tgtttcaatt
     8401 gagtttgttg ccaaagaaga aaaagtccaa tccttcttct tgttcttctt ttgtagtagt
     8461 gatcgttgta aagtgcatcg ccgattttaa aatcactgtt gtcagcacat aggcatacac
     8521 ggcagtaatg atgacaccaa tcacttgaat ccctaagaag taccagctgc ttggattcgt
     8581 tagtaaatgg ctgttagatg caaagatccc tatcagaatc gtacctgtga atccgcccat
     8641 gccatgaaca ccccacacat caagtgcatc atcccattgt ttctttttac gaaaatcaac
     8701 agcagcatga cagacgatac ccgcaatgat cccaatcagc atggcacttt ttgcttctac
     8761 ataaccggca caaggcgtaa tggctgccaa tccagcaacg gatcctgtta gtacgtcgac
     8821 aaaatcaaag ccatttcctt ttacttttgc aatgatcagc caagtaatca tcgcaaatgc
     8881 aagagcgatg aatgttgaac caaatgcatt gactgcttgt tcatctgctc gaagtgcacc
     8941 accggaatta aaaccgaacc agccaaacca aagcagtcct gtaccgatag cagctgccat
     9001 aagactgcta tgctgacttc tttctcctaa aggaatcttt ctttgaccaa gtgtgaggat
     9061 acatgctaaa gagccgaatc cagctgtcgt gtggatgact gctccaccag cgaaatctct
     9121 aaatcccatc tgatccaaaa atccgccacc ccatatccag tggcaaacag ggaaataaat
     9181 cagcagattc caaaaaataa caagtataat atagcctttt aaattcaatc tccctgcaaa
     9241 agctcctgtc atcaaaggaa cggtaatcac gataaacatc agttggtaaa gaaagaacat
     9301 taaaaatgga atcgttgcac catgaaacat gttggggaag cttgtaacat gtctcatcaa
     9361 aaagaaatct gccgggtttc caataacacc gccgatatcc cgtccaaagg ccaatccgaa
     9421 tccaccaaat acccacataa tcgttgttat cccaacggag agaaaagatt gagacatgat
     9481 cgttagtata ttattcttcc gtgctaatcc gccgtaaaaa aaagctagac caggagtcat
     9541 caggcaaacc attgctgtac ataaaatcat gaatgctgta tctcctgtat tgataggtaa
     9601 tgtattcatt tttttcgcct cctttctacg attacgagta taaaagaagg tgtagttgtt
     9661 tttttcttct gtttttttga attaatactt gcatttataa aagacagaca attaataaaa
     9721 gcttgatgtg ttgtgctctt tttcgttttt cacacaaata aagacaaaaa ataaacggtc
     9781 ttctttttat agaaaaccgt ttattttcgt ctttttttat ttttaaagat attttttcat
     9841 aaggaataaa gaatacttca tataaaatat ataaaaaaga accgcagcga gtgtcgctac
     9901 ggttctcaaa tttgttcttc atttcaacat aagtttttct tcaatttgct tataatttac
     9961 gtgcaaagaa tgaaacgact aatactaaaa tgattgcacc gatcaatgat ggaatgatag
    10021 ccattcctgc aattgttggt ccccaagttc ctagtaaagc ttgtccaatt gctgaaccta
    10081 ctaaaccagc aatgatgttt gcgatgatcc ccattgatga tcctttattc gtgattgctc
    10141 ctgcaattgc tccaatgata ccgccgacga ttaatgccca aataaatccc attttaaatt
    10201 cctcctaact gacttcttac ttcttattgt acacgtggtt cgttattttc tttgactttt
    10261 tgtgcacctt tgcctacagc agattttgct ttatctgttt ggcgtgaagc aaattgtcct
    10321 gtggattttg ctgcttctgt tactttgtct tgtactgttt cttgatcttt ttggtattct
    10381 tcttgtgttt tgatgtctgc aacattcaca ttcacttcga taacatctaa atgtgtcata
    10441 ttgtttactt cagtactgat caattctttg atttggttgt aaatatcttc gatgtcttta
    10501 ccgtattcta cgatcacatc tagatccaca gctacttgtt tcttacctac ttctgtattg
    10561 atacctgctg ttacgttatc tgtgttgact aatttttcag ccatatttga gaaaaatccg
    10621 ccatctaatg tcaatagacc atctacatct ttcaatgcat aaccgatgat tttttggatg
    10681 actttgtctt cataagtcaa ttcaccattc atcatgcggt tttctccttt ttcatttgcc
    10741 aaaactgatc catttgttgt attcatgttt ttgttttcca tctttgtttc ctcctatgat
    10801 ttaaaaaatt gatcaactat tcctgactgt ttcaaataaa aaccgattcc tgcgccaatt
    10861 gctgtcatga ttatgatcaa caatgtcttg aaaaatccaa tcgttaacca taaaacagct
    10921 agcagtagtc caagaccccc aaagataata gggagcttgt atgctgaaaa tagttctttc
    10981 attatttggc cctcctattc cactcgagag tgcttgtagt ctcttgtatc ttcttgttct
    11041 tcataaccgc tgtatgtgac tgccactttg accgtttctt ttgttccgag tactttagtt
    11101 acttcttctt cgatatcttg catcaataca cctgttttcc ctactaatga agaagttcgt
    11161 ttcaagtctc cgttgacatg gatatggatt cgatttttcg ttgaacgtat ccgtacttta
    11221 ggtgaatgaa tgaactcttc ttcgtgtaaa tgggaacgta ccaacccttc gatcgctttt
    11281 ttgtcgattg ttagtttgcc atcttcccgt ttcataacga aagttcctct tgactttgga
    11341 tagaaaagaa cgactagcaa gatgataata gcaagaacgg caaatactac agctgcccag
    11401 aaaatatatt gttgcatgta gtaattcgtt aaagtaaaga agcgaaatcg ttccaattgt
    11461 tcaggcataa tatacggcgc attgatcaac gcaatcgcta gaaatactga aagtagcagt
    11521 aaactcatga taacaccgat tatttttaac cccttattca ttttccacct cctataaact
    11581 tatttttacc ctgtaaataa ctctaccgac aatcacagta tagatagcga acagttagca
    11641 tagcatcagt aaataaagcg ctaccaaaca ttgctggatc ataacggcgt tttattgcca
    11701 gtctgatact gaaataacaa ttgcttactt attctctatt tacttttgat tgctggctat
    11761 acttaaagga tattattcaa gattaaaaat tgcaaagatt atgctcagtt attattacaa
    11821 gattctattt attt
//
LOCUS       DACCVZ010000087        11514 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.090, whole genome shotgun sequence.
ACCESSION   DACCVZ010000087 DACCVZ010000000
VERSION     DACCVZ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.090"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(79..2154)
                     /locus_tag="IVW63_002328"
     CDS             complement(79..2154)
                     /locus_tag="IVW63_002328"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAP7860590.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDIKTDRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKDHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEV
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2156..3073)
                     /gene="glyQ"
                     /locus_tag="IVW63_002329"
     CDS             complement(2156..3073)
                     /gene="glyQ"
                     /locus_tag="IVW63_002329"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAP7860591.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRF
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARSVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(3457..4269)
                     /gene="recO"
                     /locus_tag="IVW63_002330"
     CDS             complement(3457..4269)
                     /gene="recO"
                     /locus_tag="IVW63_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAP7860592.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFLSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHAYPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKMPEKNMPEKEIPEKEE"
     gene            complement(4412..5311)
                     /locus_tag="IVW63_002331"
     CDS             complement(4412..5311)
                     /locus_tag="IVW63_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAP7860593.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYTALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5326..5727)
                     /locus_tag="IVW63_002332"
     CDS             complement(5326..5727)
                     /locus_tag="IVW63_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HAP7860594.1"
                     /translation="MPMDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFG
                     ILALFMGVIFQIDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKD
                     MAAGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(5705..6181)
                     /gene="ybeY"
                     /locus_tag="IVW63_002333"
     CDS             complement(5705..6181)
                     /gene="ybeY"
                     /locus_tag="IVW63_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAP7860595.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6198..8390)
                     /locus_tag="IVW63_002334"
     CDS             complement(6198..8390)
                     /locus_tag="IVW63_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HAP7860596.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNTGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8414..9385)
                     /locus_tag="IVW63_002335"
     CDS             complement(8414..9385)
                     /locus_tag="IVW63_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAP7860597.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10090..11469
                     /gene="brnQ"
                     /locus_tag="IVW63_002336"
     CDS             10090..11469
                     /gene="brnQ"
                     /locus_tag="IVW63_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAP7860598.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
BASE COUNT         3111 a         2419 c         2104 g         3880 t
ORIGIN      
        1 ttatttatat ttataacaaa taaaccagag aaatagccta ttttgtgcct gttctctggt
       61 ttatttacat attagaaatt attttgtgat gatttgatct aaacttgcta gtgacaaagc
      121 catggcagca atttgactta attgcgttaa tcggttctta cgtactgctg gttcttctgc
      181 catgaccatc gtctgatcaa aataattttc gatcagtggg cgaaggctta caagctgatc
      241 ataattttcg ttgatcgttt ggtcagcaaa gcttgttttc attacctcta ctgctttgtg
      301 cagttctttc tccgcttcgt tttcgaacag ttcagggtct acttctgatt gtttttcaag
      361 ctccgctttt ttcgctaagt tcacgacacg tgtcaaagct tccatcgatg gtttgaagtc
      421 ttcatctgca agatgctgct tgaacaattg tgctgctgca aatacttttg tcagatcttt
      481 ttgttctgcg ttcaaaacag cttcgatgac atcatgacgg atattcttcg ttgtcaataa
      541 ttggcgcaga cggcctttga taaagtcgat cacctgttgt tgtcccgctg acaagccaat
      601 gccaaaacga tccgtatctt tactgataac ttcactaatc gtttcttgca gaacagacaa
      661 aggaaaggcc cattttttcg attcgatgat tcgaacgaca ccatatgctt gacggcgcaa
      721 agcatatgga tcgtttgagc cacttgggat catcccaact gcaaagaaag aaaagatact
      781 atctaattta tcagcaatcg ctaaaacaga acctactgta gtctcaggta aatctccttc
      841 actggatata ggcatgtaat gttcacggat cgctgttgct acggctggtt tctcgccttt
      901 aagcagagca tatttttctc ccatgatccc ttgtagttca gggaattctc ctaccatgtt
      961 ggttactaga tcaaatttat agatttcagc agcgcgttgc agatccatca attcttcctc
     1021 agacagtcct acttgttcgc ctatgatgcg agcgatgact tgtacccgtt gcattttctc
     1081 atagatgcta ccgatttttt catggaaagt aacagttttt aatttttcaa cgtattggtc
     1141 gattgaagct ttcttgtctt cattataaaa gaattccgca tcttctaaac gagcagtcaa
     1201 tactttttga ttgcctcgta ccacattttc caattttacc cgatcgccat tacgagcaga
     1261 aataaaatga ggaagcaaca taccttgatc gttccgtact tcgaaataac gttgatgttc
     1321 tttcatagaa gtgactagta cttcttcagg aacagataga tatttttctt cgaagtcgcc
     1381 agaaaagaca gttggatatt cgactagatt gttgacttct tctagtaaat cttcatctag
     1441 atcaatgatc cagtgatctt tttctgctaa ttcgtttgct tgtgtgatga tcatttcttt
     1501 tcttttttgc ggtgaagcaa taacaaattg ttcatttaat ttttcttcgt attcttttgc
     1561 atgcgcaaat gtcacatctt cgcctaagaa acgatgacct cttgaagctc tgtctgtttt
     1621 gatatccaag atctcaaacg ggattacttc gtcatctaac aatgccacga tccagtgaat
     1681 aggacggata tattcaaaat cgtattctgc ccaatgcatc gttactggga aagtgaggct
     1741 tttaatgaca tctgctaaac ctgtcaatac ttcttttgct tctttgccgt gagtgtattt
     1801 cgttacatag acatattcca cgccttttaa ttctctaaaa gtgatagcat ctgtcgtcag
     1861 accttgtccg cggacaaatc cttccgctgc tttcgtccag tttccatctg cgtccaaagc
     1921 aatttttttg gctggtcctt tgacttcttc ttcactgtct gcttgacgtt ctggaatgtt
     1981 tgttactttg attgctaaac ggcgcggtgt agaaaatgtt tcaatcgtat cataagtcaa
     2041 ttggttttca tctaaaaatt ttgctgtttt ttcttctaat tgtttcatgc ttggtgtgac
     2101 aacatgagca ggcatttctt ccagcccaat ttcaagtaat aagtcttttg ccatcttatt
     2161 cagcctcctt cacgttttct ggatttgctg tgtttttatt caataaaggg aatcctaatt
     2221 tttcgcgttc tgccacaaag attttggcta cagaacgagc catgttgcgg atacgggaaa
     2281 gataacctgc acgctccgtt acggatactg caccgcgggc atctaataaa ttgaatgtat
     2341 ggctgcattt caaaatataa tcatacgctg gatgaacaag attttcatcg atacagcgtt
     2401 tagcttcttt ttcaaaacga tcaaagttgc ttagtagcaa gtcttggtcg cttacttcaa
     2461 aagaatattt ggaatgttca tattctggtt gtttgaagat ctcgccatat ttcacgccat
     2521 cagcccattc taagtcatag acactttcaa cttcttgaat atatgaagca agacgttcta
     2581 gtccataagt aatctcagaa gtaactggtt tacaaggtag tcctccgact tgctggaagt
     2641 acgtgaattg tgtaatctcc atcccatcaa gccatacttc ccaacccaca ccggcacaac
     2701 ccatcgatgg gttctcccag ttgtcttcaa caaaacgaat atcgtgttct aatggatcaa
     2761 ttcctaaaaa acgcaagctt tctaaataaa gctcttggat attttcaggt gaaggtttca
     2821 ttacgacttg aaattgatga tgctgataca aacggtttgg gttttctcca taacgcccgt
     2881 cagctggtcg gcgggatggc tctacataag cagcattcca tggttccggt ccgattgccc
     2941 gtaagaatgt atatgggctc atcgtacctg ctcctttttc tgtatcataa gcttgcatca
     3001 gcatgcagcc gtttgatgac caaaattttt gtaatgttaa aatcatatct tggacggtca
     3061 attttttact catctgtttt gcccctttca atttttaagc gttgctgtca ataagaatac
     3121 aggaaagaaa acgacaaaaa gtccctatgt ctgattacag acatagggac gaataatttc
     3181 gcggttccac cctacttccg aataaagatt cggcagcttc atttatcgta ctcgcaagtg
     3241 cctcttcaaa aatcgtttgg gtccggcttc cactctcccg aactcgctaa accacgtgtt
     3301 ttttactgat cttggtcaat gtacgtattc attttgcagt tttcttgttt atataataga
     3361 tcctctcagt gaacgatcta tttaatctac ggttaataat agacggaagt ccctgtattt
     3421 gtcaaatagt tttgattttt ttgttgtatc tttcatttat tcttcttttt caggtatctc
     3481 tttttcaggc atatttttct ctggcatctt taatacgtgt gcccaagact tcatttgatc
     3541 aatgaacttt ttgcttttta gatgaatacc gacatattca tcatacaact ggtcaatgag
     3601 gtcacggatt gcctgcttcg tttcttcttt caagtggatt ccactgatct tatcataaga
     3661 aatagccgaa aacattcgaa cgaaataaac agcgcgagga tatgcatgat aacggtgttc
     3721 gtccattggc cagtgtttct cgcatatcac gccgccatat ttggaagaat agtcaaattt
     3781 tccttttgtt tccccgcata cgacacagtg cgtccaaatt ggcgcgattc cgaagcgttg
     3841 cagtatttga acttcaaaga tattcgtgat gatttctgca tcatctcctt ggtccatccg
     3901 ctgcagagct tgttgcgtaa attggaataa gtgcgggtca tattgatgat cttcgattgc
     3961 tgcatctact agatttagca aatacgtacc ataaccgctc aaaaagatat cttcttggat
     4021 gttccgaaac gcatggacgt ctttgacact gcttaaaaac gacaaacctt cacttagaaa
     4081 attaccgata tagactgctt cggtaaaggg gagcaaagcc ggagctaatg gctgattttg
     4141 ccgatggatt cctttgatat aaaacatcat tttgccagaa gattccgtaa agattttgac
     4201 taatttatct ttttctttgt aattacggct agataaaatc aagcctttcg attctgcaag
     4261 ctggctcata ttctccctcc taaaaaataa atctggaaaa gcagattctg ccgatccaga
     4321 ttatttatgt tacgatcttt cgctgttttt ctcaacgtac ggatttttat ccagtttatt
     4381 tctataccta acctataaga agtccagaat atcagtactc gtcttttcgg tagccgaagt
     4441 cttgcagata gacttttttg tctcgccagt ctttttggac tttgacccaa agttctagaa
     4501 atactttgtc tcctaaaaga ttttcgatat cctttcttgc tttcgttcct acttgcttca
     4561 gcatttttcc acctttgccg ataatgattc ctttttggct atctctttca acgatgatcg
     4621 tggcctggat atggatttta tcattctcgt ttcgcttcat cgaatcaaca acgactgcga
     4681 cagaatgagg cacttcgtct cgtgttaaaa acaagacttt ctcacggatc aattcagaaa
     4741 cgatgaagta ttcaggatga tcagtcactt gatcatctgg aaaatattgt gggccctctg
     4801 gcatttcact gactaataca tccattaagc gttcgacatt gtttccttct gtagcagaga
     4861 tcggaatcac ttgtgcaaaa ggcatctgcg tcgaataatc ttcgatgatt cccagcaact
     4921 cgtctggatg gatcttatcg attttattga taatcagata aactggagaa tgcacgtttt
     4981 ttagacgttc aataataaaa tcgtctcccc ggccgcgttt ttgatcagca ctgatcataa
     5041 ataagactgc atccacttct ttcaacgcag tgtaagctgc ttctaccata aaatctccta
     5101 gacgatgctt tggtttatgg attcctggtg tatcgataaa aatcagctga gcttctggtg
     5161 tagtatatac tccttggatt ttatttctag ttgtctgtgc cttgtcactc ataatggcaa
     5221 ttttttgacc cacgattcgg ttcaataatg tggattttcc tacattcggg cggccgacga
     5281 ttgcgacaaa ccctgattta tgttctggca tatacgttct cctttttaat taaacaacaa
     5341 atgatatatt ttagggacaa ataaaatcaa cccaatgatg acagcaaaac aagcggtcac
     5401 taaaactgct ccagctgcca tatctttgat ttttttccca atcggatgaa aatgaaaatc
     5461 cgtaaacatg tccactacat tttcaaaaac agtattgatg atctctacta tccaaacgag
     5521 aaaaacagct aaaagcagcc ataaccactc tatccgatca atctggaaaa tcacgcccat
     5581 aaataaagca aggataccga acgcaacatg tttcctcata ttgcgttctt cctcaaaaac
     5641 ggttttgact ccttggacag caaattccac ggacatcagg aaatgtttgt ttttctctac
     5701 gtttttatct tttgagtcca taggcatcca agatctcttt ctgtaaacca aacatttctt
     5761 tctcatcttc tggtgtcata tggtcatacc cgttgatatg caagaatcca tgtaccgcta
     5821 aaaagccaag ttcccgatca tatgaatggc cgtaagcttc tgcttgttca gcagcacgtt
     5881 caatagagat catgatgtct cctagtacac gaggcaatgg attctctcca tcttcaaaaa
     5941 tcactgggat ttcgtcttcg ccttcttctt ccagagcaaa actgatgacg tctgtcggtg
     6001 catcttttcc acggtaatca cgattgatta cttggattgc cgcattgtcc atgaaagtaa
     6061 cagacatttc tgtttcctct ggcagcttta aataagatgc tgcaaattgc agcaagtcat
     6121 cgatttcttt cattttctct tctgagactt ggtttgtttc atccataaag gtaatatcca
     6181 ttatacatcg cttctttcta ttcttcttgt tcttccttta tcttctcaac ttctgttttc
     6241 attttaggat atttgatccg agaatggaag gtgctactta aaccgctgat caatgatttt
     6301 tccacttttc ggatttcttt caaggtcaat ccactatcgt ctaattgacc atcggaaata
     6361 cgctcttcga taagattatg gacaaaactt tcgatttttt cgctcgttgg atgatccatt
     6421 gcccgtactg cagcctcaca actgtcagca atattgacga tccctgcttc acgactttgc
     6481 ggttttggtc caggataacg gaattgctct tctgttactt ccggattgcg ttctttcgct
     6541 ttgatgtaga aataacgcat tagcgtggtt ccatgatgct gtttgcaaat atcgatcacc
     6601 atttgcggca tattataatc ttccaatatt ttggctccat ctgtcacatg tccaaagata
     6661 atatgtttac tgtcttctgg caataagaaa ttgtgcgggt tttccgctcc tgaaggcaag
     6721 ttctcaacga aaaagctagc atgtttgatc ttgccgatat catgataata gcaagctact
     6781 cgagttagta aagaacgtcc gccgatttct gctacagcgt tagcacttag attagctacc
     6841 atcatactat gatgatacgt acctggcgct tcttccagca actgtttcaa taaaggatga
     6901 tttggattgc tgagttcatt taatacaatt acactgtcat cattgaccat caattcaata
     6961 tatgggtgta gaccgatcgt cagcaagaat gagaagagtg caccagtgaa cccgcagaca
     7021 agcattaacc aagtcgttgc atcaccaaag ctcattcctt gatagacgat caaaatgaca
     7081 tccatcatca caggaaaaat aatgacccac atggcagcag ataatccttg ttctgagatc
     7141 cgtttacgtc tgacaatcgt tgccatgagc ccagagaaaa cataagacat caagataatc
     7201 gttagaaagt tcgtgccaat cgaatcataa aaaatgaaaa gtgcggatac tgcttggaaa
     7261 ataccagcca tgatccctgc tcttcgattc aagaaaaagc ttaaaacaag tggtgcaaaa
     7321 gcagcgggat aaaacagcgg gatataagta gcttgttccg tttggaataa ttggaaaaat
     7381 ttcatcagca ctatgctgac tgacatagct gtcacataga aaagaacgta ttttgttctt
     7441 tctcctgtat tttggaattg aagtgaatta taaatcagta cgccgatttg aagcaaaaca
     7501 gctaaaacca tggcaattag cggaaaaatc gaagttgttt gattagtcag tcctagtaat
     7561 tccaattttt tcatagctga agcatcaatt tgattacctt cacgaacaat gatttctcct
     7621 tggaagatca tcactggttg tacagcttct cgtgcggatt gtttcaattc ttctgtcttt
     7681 ttctcattca atacgtcatt cactacgata ccttgatcca ctaagtagcg aatcatttgt
     7741 tgttgtgctg gtgtgacatt caaatattgg atttgctctt ctgcttcttg tttaaaagct
     7801 tccaattcac tttcacgaac ttgtttgctc atctgttcgt caatgagctt cagactctca
     7861 tccctcacag tatgaatctc agtttcagtc atttcaaata tcgtcgaata aaaattgttc
     7921 ggtagttttt gataaaacac aacattttct gcattcacat tttcaaaatt tttcttcagc
     7981 gcggcgatcc gctcttctgt agtaggcttt gggatatttt catcttcctt tgccttatca
     8041 atcttttcgt cataagattt gttgatggca tcattcgtct tatcgatcaa ttcaaatagt
     8101 tgcttgatcc gattgttctg gtcatctgca agatcttttt ggtaagtgta ttctggagtg
     8161 actgcttctg ctgccagttt tcttttttgt tcggtttctt ccgtgttctc gatcgttttg
     8221 ttcgcacgga tactttcttc tgctacttgg ccttctctga aatcattggc cttttgtttg
     8281 acactactaa atgtaacgcc gcagataatg ataaaaaaca agaacagcag gaaaggcaat
     8341 gctgcctttc caagtttttc ttgtagtttc tgcagtgttt tattcaacat gtgcttatcc
     8401 tcctaagcaa agcttattct tgatggagat ctgccttttc ataagctttg atgatttcgg
     8461 caactacagg gtgccgaaca acgtcacttg cttcaaaatt aacaaaatcg attttcttga
     8521 tttgctttaa tgttcgttct gcatgaacaa gaccacttgt tgtccctcga ggcagatcaa
     8581 tctgactcgt atctccattg acaatcattt ttgattgata accaagacgt gtcaggaaca
     8641 ttttcatctg agcaactgtc gtgttctgtg cttcatccaa aataacgaat gcatcatcca
     8701 atgtccgccc ccgcatgtaa gctaaaggag caatttcgat cacgcctcgt tccatcaatc
     8761 ggttcgtatg atctaatcca aaaatttggt ataaagcatc ataaacagga cgcagataag
     8821 gatctacttt ttcttttaga tccccgggaa gaaagcctag attttcccct gcttccacag
     8881 caggccgcgt caaaatgatt ttttgcactt cacctttttt caaggcagcg attgctaata
     8941 ctactgcaag aaaagttttt cctgtcccgg ctggtcctac gccaaatacg atatcatgtt
     9001 tggctaccga ttcgacatat ttcttttggc cgctgttttt tacccgtata ggttttccat
     9061 tacggtcttt gacgatctct tcctcataca tctcaacaaa ataatctaat gtgccttttt
     9121 gccccatttt cagtgccgtc acgacatctg gtgtacttac atggattcct cgtttgatca
     9181 attcctgcaa tgtccgaatg actgaggcag ccaaggaaat ctgggattgt tcgccaatga
     9241 tctgaatgat ttctccacgt gtatggatgg ttgtttctgt tgtttcttca atcagtttta
     9301 tgtgcttgtc gtgtgcacct aaaagcatgc tgacatcatc agcagccgtc aatctaatct
     9361 ctaaagaact agactcttcc gtcaaaaata gacatcccct ttttttcgat tcattctttc
     9421 ctattttacc atactcagaa gaaactatat agcaaataag aaaaggttct aaaagagttg
     9481 cttaaccata agtaccaaga aacgttaaaa aatagctgct tccattctct aaaggtctcg
     9541 tttgaataaa aaaagctgat catgtaagct atgcataaga tagaggacaa gtattccgtc
     9601 taacttagca agtattctct gggtattttt cttgtttcaa aaaaagaaaa caaaatattt
     9661 gaaatattct tgcatttcaa aaaaaacagg tgtattataa cgtcaacaaa taaatataca
     9721 gcaaagcgtc gaggaaaaca gtaggctatt cagtgattta ttcccagtga gtcatgtaag
     9781 tgagaaatga caataaatcg aatagacgaa catcatttcc gagtcaatgt cgaaaacgta
     9841 gatcattgtg gctgcctcca ttatcaggcc agcggataac tttatcgaaa agcgtccgtg
     9901 aatgaagaag cttttttaag cgaaaaaagg tggtaccgtt ctagaatcta gagccctttt
     9961 cccaagtgga aaagggcttt ttttatattt taaggtggtg gttttcatgg aatctgatat
    10021 tagtggtatt tctagtttct gcaacgttta ttttgttact caaaatgata attattggag
    10081 gaaaaattta tggaagaaac aaaaacttat tcatggaagc aattattgat ggtcagttca
    10141 cttatcttcg ggatgttctt cgggtcaggt aatctgatct ttcctgtcca cttaggtcaa
    10201 atggctggat caaactggat cagcgctggt gtaggatttg ccatctcagg cgctcttttc
    10261 ccattattag ctatcttagc tgtagtagtg acaaaaagtg atggtctgta tgacttagct
    10321 aaacctgtcg gaaaatggta tgctgccttg ttcttgatcc ttgttcattt aacgatcgga
    10381 ccattctttg gtacaccgcg gacagcagca actgcttttg aaatggctgc taaacccttt
    10441 ttgcctgaaa aatatgattc attaggtatg tttttattct ctgctctttt ctttttactt
    10501 gcttatttcc ttactgtaca tccaacacgt ttggtcaaat atgtcggaaa gtatttaaac
    10561 tccttgtttc ttgcattatt agctatcatt tttgtcgttt ctttattcca acccatgggg
    10621 aatctaaacc aatctgctgc agattcttat cagacgaacg ctttgacaaa tggcgtttta
    10681 gaaggataca acacggttga tgcagtagct ttacttgctt taagtgtcac ttttgtccat
    10741 gcagttcgtg atcttggttt taaagataaa aaagtcacag aattaacagc aaaagctggt
    10801 agcctgagcg ttgcgttaga agtcatgatt tattttggtc tggtccttct cggtgcgatg
    10861 agtttgaata agatgtcttt atcagaaaat ggcggaactg cactttctca gatcactaat
    10921 ttttatttag gtaacttcgg tgctagcttc ttaggggtaa tggtcacatt aggtgtcttc
    10981 actaccgcta tgggactcgt tgtttctttt gcacaagatt tccataaact gttccctaaa
    11041 gtcagttata tgacatggct gcggttaacg acttttgtct cttttgtcgt tgcgaatgcc
    11101 ggattggata atatcatcca atggtcttta ccagtattga tgcttttgta tccattgtca
    11161 cttgcgttaa tcttgctttc cttaacagca aaattcttcc aaaagagtcc atttgtctat
    11221 caagtaacga tgttcttttc tgccgttcca gccgtattgg atatgttggc aaattcgcct
    11281 gcattagtga gtcagcaaac tgtcgtagca agcttactag gattttatca tcattatgtt
    11341 ccttttgctg cattaggact tggctgggtc gtcccaacgt tgcttggtta cgctggcagc
    11401 ttgctctttt attatgtata tcgcgtatca ggatataaac aagaagcaag tgagttacca
    11461 gaagaataac caaatcaaac acaatttaac ataagagata ttaaacagga aaaa
//
LOCUS       DACCVZ010000088        11477 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.091, whole genome shotgun sequence.
ACCESSION   DACCVZ010000088 DACCVZ010000000
VERSION     DACCVZ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11477
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.091"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            413..970
                     /locus_tag="IVW63_002337"
                     /pseudo
     CDS             413..970
                     /locus_tag="IVW63_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            1028..3067
                     /locus_tag="IVW63_002338"
     CDS             1028..3067
                     /locus_tag="IVW63_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAP7860599.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDQYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGRKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(3176..4327)
                     /locus_tag="IVW63_002339"
     CDS             complement(3176..4327)
                     /locus_tag="IVW63_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAP7860600.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVFLLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(4481..5011)
                     /locus_tag="IVW63_002340"
     CDS             complement(4481..5011)
                     /locus_tag="IVW63_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860601.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(5110..5460)
                     /locus_tag="IVW63_002341"
     CDS             complement(5110..5460)
                     /locus_tag="IVW63_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HAP7860602.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(5617..7146)
                     /gene="ahpF"
                     /locus_tag="IVW63_002342"
     CDS             complement(5617..7146)
                     /gene="ahpF"
                     /locus_tag="IVW63_002342"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAP7860603.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(7156..7719)
                     /gene="ahpC"
                     /locus_tag="IVW63_002343"
     CDS             complement(7156..7719)
                     /gene="ahpC"
                     /locus_tag="IVW63_002343"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAP7860604.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(7863..8525)
                     /locus_tag="IVW63_002344"
     CDS             complement(7863..8525)
                     /locus_tag="IVW63_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7860605.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8709..10355
                     /locus_tag="IVW63_002345"
     CDS             8709..10355
                     /locus_tag="IVW63_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAP7860606.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            10346..11428
                     /gene="uxuA"
                     /locus_tag="IVW63_002346"
     CDS             10346..11428
                     /gene="uxuA"
                     /locus_tag="IVW63_002346"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAP7860607.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
BASE COUNT         3864 a         2147 c         2167 g         3299 t
ORIGIN      
        1 aaaaaatatt aaagattgtt aaatttcact atttcatttc aaattccatt gcctaatcat
       61 taggaaaagt ctatcatgaa ctcgtaaata gaatatagta ataaccttgt taggtgaggc
      121 tcctatacaa acataggctg ttgcccagaa acgtcgaaag tcgccaatgg gtaaaacaga
      181 aactgttgga ttaaggcttt ttccaatagc taagaatgtt ttctttacgt tgtatagtgc
      241 taaaactcgg acgatgagat gatgctaggt cagaattctt gttcgaaaag gtttctgacc
      301 ttttctttat atttttgtga ctgacttatt tgatgagaca aactcgctcc tcacctgaca
      361 agtggattgc tgtgtgagga ggagatgcgg tgaaaaaaga tcgattggtg gaggtcgctc
      421 ggattcactt ctggttgcac aatacaacca gaaaacacaa caagcaaaac tgatctctat
      481 catgagagat tcatatgtcg atattccagg ttacggaatg aataagataa atgcagctta
      541 ctcttatggg ggagttgatt tattaaatca aacattaaag gaaaatttca aatttgaagc
      601 tccctattat gcaagtatca catttcaaga ttttatcgat tgcgttaatg aactgtttcc
      661 tggtggagtc aagatcgatg cagaaaaatc tctagattta gatggcgtat atataaacaa
      721 aggagagcaa gtgatggatg gtaatacttt actccagtat gctcgatttc gggaagacaa
      781 agaaggagac ttcgggagga tcagaaggca gcagcaagtg atcaaagcta tctctcagca
      841 gctgaaagac gtaacttcaa tattcaagct acccaaagcg gttgggaaat tacttggtag
      901 tatccaaacg aaccttccag aaagtgtgct tctggattgt ggtatggatt tcctcaaaga
      961 catatgttag aataaacagg tataaatagt gaaataaagg aatgacaagc aagagaagga
     1021 ggaaaaaatg aaaagaagtg acaagcacgg caaaaatcga acaggcgctt atattgccgg
     1081 cgcagtgatc ttaatagcag ctgcgggtgg cggttatttt tactaccagc actatcaaga
     1141 aacccaagca gtagaagctg gagaaaagac agttgagcaa tttgtccaag ctttgaacaa
     1201 gggagattat aacaaagctg cagaaatgac atcaaaaaag gcggcaaata aaagtgcatt
     1261 atctgaaaaa gagatcttag atcaatacca gaatatatac ggtgctgctg atgtcaaagg
     1321 acttcagata tcgaatctaa aagtagataa aaaagacgat tctacttaca gtttttcata
     1381 taaagcaaag atgaatacct cattaggtga attgaaagat ctttcttata aaggaacatt
     1441 agacagaaat gatggtcaaa ccacgatcaa ctggcaaccc aacttggttt ttccagaaat
     1501 ggaaggaaat gacaaagtaa gcctgaccac acaagaagca gcaagaggga atattataga
     1561 tcgaaatggt gaaccattag caacaacagg caaactaaaa caattaggag tcgttccaag
     1621 taaacttgga gatggaggcg aaaaaacagc caatatcaaa gcgattgctt cctccttcga
     1681 cttaacagaa gatgctatca atcaggcgat ttcacaaagc tgggtacaac ccgattactt
     1741 tgtcccattg aaaatcattg atggagcaac gccagaactt ccagctggag ctaccattca
     1801 agaagtagac ggcagatatt atcctttggg tgaagcagct gctcagctga ttggttacgt
     1861 gggagatatc acagcagaag atattgataa gaatccagaa ttaagcagta atggaaaaat
     1921 cggtcgctca ggtttggaga tggcttttga taaggatctt cgtgggacaa caggtaggaa
     1981 attaagcatt acagatgcag acggtgtaga gaaaaaagtt ctgatcgaac atgaagttca
     2041 aaatggcaaa gatatcaaat tgacaatcga tgcgaaggca caaaaaacag cttttgacag
     2101 tctaggagga aaagctggat caactgttgc gacaacgcca aaaaccggtg atcttcttgc
     2161 gcttgctagc tctccaagct atgatccaaa caaaatgaca aacgggatct cacaagaaga
     2221 ttacaaagct tatgaagaaa atcctgaaca tccattcatc agccgatttg cgacaggtta
     2281 tgctcctgga tctacgttta aaataattac agcagcaatc ggtctcgaca acggcactat
     2341 cgatccaaat gaagtgttga cgatcaacgg gcttaaatgg caaaaagaca gttcttgggg
     2401 atcttttaaa acaacgcgtg tcagtagtga tgtatcacaa gtagacttaa aaactgcttt
     2461 gatctattcc gataatatat atgcggcaca agaaacgttg aaaatgggtg agaaaaaatt
     2521 tcgtacaggc ttagataaat tcatttttgg tgaagacctt gatttgccaa ttagtatgaa
     2581 tccagcacaa atttctaatg aagatagctt taactcagat atcttgctag ctgatactgg
     2641 atatggacag ggcgaacttc taattactcc tatccagcaa gcagcaatgt attctgtttt
     2701 taccaacaat ggcacacttg tctatcctaa attgattgca gataaagaga caaaagataa
     2761 gaagaatgtc atcagcgaaa cagcagtaca aacgatcgtg ccagatctga gagaagttgt
     2821 gcaagatgta aatggtacag cacattctct ttctgcttta gggattccgt tggcagcgaa
     2881 aactggtaca gcggaaatca aagaaaaaca ggatgtaaag gggcaagaga acagtttctt
     2941 gtttgctttc aatcttgata accaaggtta tatgatggtc agcatgttgg aaaataaaga
     3001 agatgatgat tcagcaacca aacgagcatc ggaactattg caatacctca accaaaatta
     3061 tcaataaaaa attgcttttt aagtacagta aaaggactgt ggcgttatcg tcacagtcct
     3121 tttttcaaat aaacggtttt cacgatgtct ctttcacaac ttctttttga tttactcaca
     3181 cttcataaac tttttttgta aaatatttga gaacaagtgg agaaataagt gtacttaata
     3241 aaatcacgat aactaaaggt gaatagtact gtggttcgat caattgactt tgctgtccaa
     3301 tttgtaaaat gatcaaagcc atttctccac gcgaaatcat accagcaccg accatcaatg
     3361 aactatgttg agaaaaaccg gcaatctgag caccaaaata acctccaagc aatttggtca
     3421 aaatcgctac aagcgtcaat atagaaataa agagtagttg ttcactaaag tcagaaaaat
     3481 caacttctaa tcctacactg acaaaaaata ctggtataaa tactgcatat cctaaagcct
     3541 ctacattgtg gtatacttct tctttaacct ttgtctgact gacagctatc ccagcaaaaa
     3601 aagcaccaat gacagagcta agcccaacaa gatccgctac gtaagacatt cctaaacaaa
     3661 taactagcga tacgatgata atagaagaat ttgcgtacac tttttctgca aatgaaagta
     3721 ggaaaggcgc aatccatttg actaataaga aaataaaaac aaaataaatt agctgttcaa
     3781 tcaaaacaag cggtaaagaa gcattgctag aagcttcccc cgttagaaaa gataggctga
     3841 aacttagaac taaaacgact aaaatgtcat ctaccacaga agcacccaaa attgttgatc
     3901 cttcttttgt attcactacg tttagttctt ttaatacttc tactgaaata ctgacagaag
     3961 ttgccgcaag aataatccca aagaaaatcg cttcatttcc cgaaacttgg aatgctttgc
     4021 ctgtcaacca gccaaaaaca accgggaaga tgatcccaag caaagcaacg aacataccag
     4081 gtcggaaata ttttttcaaa agagataaat cactttccag accagctaaa aacattaata
     4141 agaacacacc aatctccgaa aagtcatgga ctagaatatc aggtttgacc caattcaatc
     4201 cagcttggcc tagcaaaaca ccaacaagta attgtccaat cactgctggg atacctaatc
     4261 tccgcgagat atgtgagcca atcgttgttg aaatcaatat caggcataaa ataccaataa
     4321 attccattct catcattcct ttgtataaaa tatagcccga acttagcata acatacatta
     4381 ttgaaaaaat aggaaaatat actcacaaaa aaaccaacaa tccaaaagat ttttttggat
     4441 tgttggtttt tatacggtct attttaataa ctaaaaatga ttaacgtata gtcatttttc
     4501 ttattctgat gaaattgata atctcctgga tgcccatgaa aatcaaaata aagccgaata
     4561 tttggaatag aagcatcaaa cttttgaatg gattgaacaa taagacgaat ccgccaatca
     4621 acaacagaat actactataa acactccaac ttttagcttt tgtattcatg ctgaagaaca
     4681 actggaacaa gctgttgatg ataacagcta atccaagaag aatcggcagg atagaaacga
     4741 ttgcaggtgc aaaagcatag acgatcagag ctaagatcag gaaaaaaaga ccactgaaca
     4801 gaccgatact ccaagaacct gttttccttt taaaacggta agcctcaaaa agattcaaca
     4861 acccaagcaa aacaagatag gcggtgatca gataaccgat aaaatgaaaa acagcagaag
     4921 ggtttagcac aatcgcaatc ccagaaataa tataaacagc agctcttaat aaggcgtatt
     4981 tttgaatatt ttgtttaatc gtctcaaaca tataagaaaa cctcctttga cttattttaa
     5041 cgtgaactag tcattttacc aaattaaatg ttacaaaatg agcgaaggag aagaatatct
     5101 ctggaaaaat caacttctga ggatcttttc catttttttg ccttttgcta gctcatcgat
     5161 cattttatct aaataacgaa tttctttcat caagttatcc tcgatgtctt ctactcgtac
     5221 accacaaaca acacctgtaa tcaaggaacg tgaaggattg gggacagggg cttccgcaaa
     5281 aaattgttcg aaagtcactt gtttttgtag ttgatattct agttctgttt gggaataacc
     5341 cgtcagccaa caaatgattt catctacttc ctcttttata cgatcttttc tctccgcttt
     5401 tgctacatac ataggataaa cgcttgcaaa acttgtcgta aaaatacgat tttgcgccat
     5461 aatcagtcac ctttcttttt ttcaaattat ttactactta tagtatataa gaaaaagaga
     5521 agaaaaagcg attattcaaa aaaacaaaaa ggattgtgac aaaattcttg tcaccatcct
     5581 tttttccgct ctctgacttt ttacaatctt catagctcaa gtgcgcatca gataatcgaa
     5641 tgctcctaaa gctgcagtag ctcctgaacc cattgaaaca atgatttgtt tgtatggact
     5701 atctgtacaa tcaccagctg cgaaaacgcc ggggatattc gttgcgccat ttttctcggt
     5761 cactatttca tttcttggat tcatttcgat cgttccatct agccaatccg tattagggag
     5821 taagccgact agaatgaata ctcctgaaac agctagtgta tgcatctcca tcgtacggcg
     5881 atcgatatag gagagagatt ctacctgatt cgtaccgctg atttctttcg tcgctgcatg
     5941 tttgataaca gtgacattcg caagagagac tagtttatcc tgtaagattt gatctgcttt
     6001 taattctggt aagaattcta gaacatatac atgttttgct aacccagcca aatcgattgc
     6061 tgcttcaaca ccagaattac caccaccgat aacagcaatc tcttttcctt taaataaagg
     6121 gccgtcacag tgtgggcaat aagcaattcc tttattttta aactcttttt cgcctggtac
     6181 attgatagaa cgccagtgcg cacctgtcgc gatgatggcg gtttttgctt taagtgatat
     6241 accgttagct aagccaatat taataaaatg ttgctcttta tttaaggaaa cggcctgttg
     6301 attcatcata atgtcgatag ggtaactacg cacatgactt tctacttgct gcatcaattt
     6361 tggaccttct gtgtaagagg taccaatcat attttcaatc cctagtgttt caacgacttg
     6421 tccgccgaaa gaatcagcga caagtcctgt acggattcct ttacgtgctg catagatagc
     6481 tgcactacta gctgctggtc caccgccaat cactaataca tcataaggtt ctttttcaaa
     6541 caactcttct tcaatcaaag ggccagtgat tttttcaaca atttgttcga tcgtcatgcg
     6601 tccgctacta aattcttctc catttaaaaa cacagttggc actgccatga tttttttatc
     6661 atcgatttct ttttggaaca tcccaccttc aatcatcgta tgagtaatat ttggatttaa
     6721 tacagctaat atattcaatg cctgtacaac gtcggggcaa ttatgacaag tcaagctaac
     6781 ataactgtca aaatgcaatg tttgtgttat ttttttgatt ttaagactca aagattcact
     6841 gattttcggt gcccgtccac taatttgtaa catagccagt aaaaaagagg aaaattcatg
     6901 accgaggggg ataccagcaa aaacgattcc actttctttg ccaactggat tgatagaaaa
     6961 actaggtgtg cgcatcgaat ctcttttttc ccaagagatt ttaggagaca tttctgctat
     7021 ttccttcgta aattcagcta gtttttgact attttcacta ttatccaaac taacagaaaa
     7081 aacaatagga gattcaatca gtgctaaata ttgttcgaga ttttgtttag tttctttgtc
     7141 taacatatcc accacctaaa tctttccaac aagatcaaaa cttggtttca atgtttcgcc
     7201 actttctttc cattttgccg gacaaacttc acctgggtgg gtacgtacat attgagcagc
     7261 gcgaatctta tcaatcagtg cactagcgtc acgaccgatt ccatctgcat tgatttccat
     7321 agcttgaacg attccgtctg gatcaataat aaatgttcct cgctgagcta atccttgctc
     7381 ttcatccaaa acatcaaaaa tacgagaaat ctgatgagac ggatcaccga tcatcacgta
     7441 ttcgatttta ccgatagcat ctgatgtatc atgccatgct ttgtgagtaa agtgggtatc
     7501 ggtagagcaa gaaaagactt caacacctaa agatttcaat gtactgtatt gttcttgtaa
     7561 gtcttctaat tcagtaggac aaacaaaagt aaaatcagct ggatagaagc aaagaatact
     7621 ccagttcccc ataagatctt tttcactgac ttctaaaaat tctccttgat gataagcatg
     7681 tgcattaaat tcttcgattt ttttcccaat caatgacata gtaaaacctc caacaataat
     7741 tatttattta taattattgt aatttagttg gagttgcaaa gtcaatggat attttgttat
     7801 ttaataaaga ttactcaaaa acgaaggtta attataaaaa tagaagaggt cgcaagaaaa
     7861 tgctactgct ggaaatactc gggataacgt tgagtaacag tttcctgttc tttcagcatc
     7921 atgtgtaagt gcaatcccgt ttgaaatcga gcttcttctg gttttttatc aactaaagcc
     7981 ttgagtaaat cataatgttg ttccatgatc gtttcccatg gaagcccctg aatggtcact
     8041 cgtaaccagc ggaaacgttc taaatgggta ttatggtcat ctaaccagtt ccaaacttct
     8101 tttcttcctg caatttcgaa acaagcttca tgaaataaat tatctgcacg gaaaaaagcg
     8161 cgttcgtcat ttattttgac tgctttttct tgttcttcta aaatcgtttc tagcactatt
     8221 cgtgtttgtg tgtccaattt ggaacaacat tcaatcatga tttgctcttc caactgttct
     8281 cggacaaagc gagcattttc tgcagaaaca agattaattt ttgaaacata cgtaccactt
     8341 tgaggtatcg tatacacgag ttcttgctga cgtagttgaa tcaatgcttc gcgaatggga
     8401 gtccggccga tagcaagatg ttcctccagt gccttttcag atattttcct tccaggttct
     8461 aagtcagcat agataatttg tttacgaatc gcttgataag cttgagattg caagctgctt
     8521 ttcatcttta ttcctccaaa atcatttcta tgaacgtagt ataacagaag aggtctgaaa
     8581 aacaatctgg tatgtcacat taactagtaa atttgtataa atagtaaaat tttggttgac
     8641 atagcgattt ttattgcata aaattcactt gaatacaaaa actaatatgt tagtttagga
     8701 ggggaaaaat gattgattta aacaactgga ggaactttat ccctgaatta tctcaaaaag
     8761 aagtagaaat acctcatttt gaccgtgcat cattaagaga aaatggacaa aaaaatcctg
     8821 tctggatcca tttcggtggc ggaaatcttt atcgaggatt tcatgcagaa atcgctcaac
     8881 gtttagcgga tctaggcgaa ttgtccactg gtgtcattgt ttgtgaaaca ttcgatgaag
     8941 aaataattga aagggcttac caagattttg atgatttgat tcttgaagtg gtcatgccaa
     9001 gcagtggaga gttcgtcaaa cgtatattag ctgcgacagc tgacagtctg tattgtcatc
     9061 cagattgttc tgaacacttt gataagatga ttcgacactt tgaaaatcct agtttacaat
     9121 tagttacttt tgctattact gaaaaaggtt atcgattgaa agatacaaat aataaatata
     9181 taggaccgat tgcagtcgat ataaaaaatg gtccaaagaa gccatcacat acaatgagta
     9241 ttcttgctgc gctactttat aaacgttttt tatctggagc ttggccgatt gcacttgtct
     9301 ctacagataa tttttcacaa aacggtagtc aattacgtac ttctttgcta acgatcgcaa
     9361 aagaatggca aaaggaaggt tatgtacaaa atacatttat ccaatactta tcgaatgaag
     9421 aaattgttgc gtttccatgg acgatgattg atcgtatcac cccgaatcct tccttgtcag
     9481 ttagcaaaat gttggcaaaa gagggctttt caaatatgtc gattttccaa accgcaaaag
     9541 gaaataatat tgctccattt gtcaatacag aggacatcca ttatttaatc atggaagatc
     9601 attttcccaa tggacgtccg aaattcgaaa aagctggagt attcttgact gatcgtgcaa
     9661 cggtagataa agcagatacg atgaaggtga cgacttgcct taatcctttg catacgtctt
     9721 tagctattat gggttgttta ctggggtata ggagcatagc tgaggagatg aaagatccag
     9781 atttatcgct gctagtttct gaaatcgggt acaatgaagg cctcccagtt gtggagtctc
     9841 caggtatcat tgatccaaag atctttctgg aagaagtaat tactgtgcgc ttttctaatc
     9901 caaatattcc tgatatgcct cagcgaatcg ccacggatac ctctcaaaag gtggcgattc
     9961 gttatggtga gacgattaaa aaatatatgg aaatagaagt taaagacccg cagacacttg
    10021 tattcatacc attgactctc gctgcttggc ttcgatacct tattggcatt gatgatcaag
    10081 gaaaaccatt catcccgagt ccagacccac tattgacaga ctttcagcat aagctttccg
    10141 atattcaact gggtacgcaa gatacatcac atattcatga gaaaatggct cctattttgt
    10201 caaataaaga aatttttggt gtagatcttt accaagcaga gcttggcaga aaaatagaag
    10261 aaatgttcat caagatggta gcaggaccga atgccgtacg aaaaacatta caggattact
    10321 tacaagaaca tggaggaaat ttatcatgga aatgactttt agatggtacg gatcacagga
    10381 agaaaagatt accttagatg aaatcagaca gattcctgcg gtcaaaggga ttgtaggcac
    10441 attgatggat ataccagtag gagaggtatg gcctagggag aggatcaaag aactaaaaga
    10501 agaaattgag tctcgtgggt taacactaaa agtaattgaa agcgtcaatg tgcatgatgc
    10561 cattaaaatt ggattacctt cccgtgagca gtatatcgaa aactataagc agacaatccg
    10621 aaacttggca gaatatggaa tagaagtcat ctgctataat tttatgcctg tatttgactg
    10681 ggtgaaatct gaccttgact accgcttaga agacggctca tccacgttag cttttatatc
    10741 tgatgatatt ccagatgatc caagagaaat cgtcgcgcgc atcgaacatt ccagcaatga
    10801 atttgaattg ccgggatggg aacctgagcg cttagctcat atcaaatcct tgcttgaagc
    10861 ctatgcatca gtagacgaag aaaaacttcg agaaaatttt gcctattttc tccaatcaat
    10921 catcccaaca tgtgaagagg taggggtcaa aatggctgta catccagatg atccgccata
    10981 ctcgattttt ggattacctc gaatcgtaaa gaatcgagaa gatttagatt ggttgtgccg
    11041 catagtagac agcccttata acggaatcac tctttgtaca gggagtattg cagaagatcc
    11101 agaaaatgat gtatatggga ttttagcaga attttgtcaa agagatcgaa tcccatttgc
    11161 acatgttcga aatattaaat ttttagctaa tcgagatttc tatgaggcac cgcataaatc
    11221 cgaatacggt tcattagaca tgtaccgcat actaaaaaca atgtatgaca acggatttaa
    11281 cggatacatc cgtcctgatc atggaagaat gatctggaat gagacaggaa gaccaggata
    11341 cggcttatat gatcgagcat taggtgctgt ttatctaaat ggattatggg aagcaatcga
    11401 aaaaggaaac aaaagtaaag ataattagtg aaaaaaactg taattttatt atgtaaataa
    11461 gaaggatgtt caaattc
//
LOCUS       DACCVZ010000089        11357 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.092, whole genome shotgun sequence.
ACCESSION   DACCVZ010000089 DACCVZ010000000
VERSION     DACCVZ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.092"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..1031)
                     /locus_tag="IVW63_002347"
     CDS             complement(<1..1031)
                     /locus_tag="IVW63_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7860608.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1113..1802)
                     /locus_tag="IVW63_002348"
     CDS             complement(1113..1802)
                     /locus_tag="IVW63_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP7860609.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="IVW63_002349"
     CDS             complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="IVW63_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAP7860610.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2329..2832)
                     /locus_tag="IVW63_002350"
     CDS             complement(2329..2832)
                     /locus_tag="IVW63_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAP7860611.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     gene            complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="IVW63_002351"
     CDS             complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="IVW63_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAP7860612.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="IVW63_002352"
     CDS             complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="IVW63_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAP7860613.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4800..5468
                     /gene="sdaAB"
                     /locus_tag="IVW63_002353"
     CDS             4800..5468
                     /gene="sdaAB"
                     /locus_tag="IVW63_002353"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit beta"
                     /protein_id="HAP7860614.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5481..6353
                     /gene="sdaAA"
                     /locus_tag="IVW63_002354"
     CDS             5481..6353
                     /gene="sdaAA"
                     /locus_tag="IVW63_002354"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HAP7860615.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6444..7463)
                     /locus_tag="IVW63_002355"
     CDS             complement(6444..7463)
                     /locus_tag="IVW63_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAP7860616.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7636..8523)
                     /locus_tag="IVW63_002356"
     CDS             complement(7636..8523)
                     /locus_tag="IVW63_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP7860617.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="IVW63_002357"
     CDS             complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="IVW63_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAP7860618.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9246..9416)
                     /gene="secE"
                     /locus_tag="IVW63_002358"
     CDS             complement(9246..9416)
                     /gene="secE"
                     /locus_tag="IVW63_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAP7860619.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="IVW63_002359"
     CDS             complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="IVW63_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP7860620.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9754..10398
                     /locus_tag="IVW63_002360"
     CDS             9754..10398
                     /locus_tag="IVW63_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP7860621.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10454..10957)
                     /locus_tag="IVW63_002361"
     CDS             complement(10454..10957)
                     /locus_tag="IVW63_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAP7860622.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10970..11016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
BASE COUNT         3313 a         2361 c         2078 g         3605 t
ORIGIN      
        1 aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg tgtttgattg
       61 gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag caaaatggcc
      121 aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac aagtcccata
      181 tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg tgcagcaact
      241 gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca attgtaggcg
      301 ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc aaacatgaaa
      361 aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg cggcaaactt
      421 ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg cggcattttc
      481 cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata gatcatccgc
      541 caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat ccccacgagt
      601 aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc tagtaccgca
      661 ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa agaagcgcat
      721 gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca gagagacggc agataacgct
      781 accattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac taaaaacagt
      841 aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc acttgtgcta
      901 acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat attggcaaca
      961 acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg tgttttttca
     1021 ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg aaaagattgg
     1081 aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt tccttgtttt
     1141 ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac acttgcaacc
     1201 aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca cgcatacaac
     1261 acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag aggcaatttc
     1321 atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat atagcctaac
     1381 attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg attcgtttcg
     1441 gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat gttaccaaga
     1501 gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa accagcaatg
     1561 actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt caatacgatc
     1621 aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc tgccttactc
     1681 gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa ccgatagccc
     1741 actaccagta tcagaatgat tcccaacgag atcaacatca atcggattat tttctttttc
     1801 atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata aaaacaaaaa
     1861 agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta tttaacagtt
     1921 acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc tttagatacg
     1981 ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt caagcctaaa
     2041 ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc tgcagttaat
     2101 tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc agctacagct
     2161 acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag gtcgttaagt
     2221 tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa tgccattata
     2281 atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt aagctgcatc
     2341 tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg
     2401 tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt
     2461 gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt ctaatgcttt
     2521 tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt cgttactgaa
     2581 tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag cttttttagc
     2641 tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat cacgaagttg
     2701 tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga ctactactga
     2761 tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt ttgcgataat
     2821 tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt tttgcactga
     2881 aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca cctattcact
     2941 tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc
     3001 agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa actctatgcc
     3061 accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta ggaaattaag
     3121 gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact agcttagcat
     3181 gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt ctaatattta
     3241 attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg atcgttacat
     3301 ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca tcatggattg
     3361 ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt ggtacatgga
     3421 tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg tttactgctt
     3481 ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct tttggtccta
     3541 atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca actacatcaa
     3601 agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg aaatctgcac
     3661 cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt
     3721 taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct tttttagggt
     3781 ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt
     3841 ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact ttttttaatg
     3901 catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg tggttataac
     3961 ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga agctgctgtc
     4021 ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg
     4081 cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc agcgatttct
     4141 cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc tgaacctttt
     4201 tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt aacgaatgtg
     4261 aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc ttgatcagct
     4321 gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg acctagtgca
     4381 ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt aacgattttt
     4441 tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta attggagatg
     4501 catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa
     4561 caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt tttctgctat
     4621 ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa tttttcgttc
     4681 tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa agcaaacaat
     4741 aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag gtggagaaaa
     4801 tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg attggtccaa
     4861 gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt atatttggcg
     4921 aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc tatcgggggc
     4981 acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat gatgaacgtt
     5041 tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt gttcctaaga
     5101 gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga acacgaaagc
     5161 tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa ttgaatggat
     5221 tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa gatgttccag
     5281 gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc ggcactatga
     5341 cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta gatgatcctc
     5401 aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc gtaaattatt
     5461 tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat caagcaaaag
     5521 cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt ggccgttccc
     5581 gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa tcaatcaacg
     5641 agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca aaaaaattag
     5701 atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa gctgtacgca
     5761 atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct acaccgactg
     5821 ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg cttgatttga
     5881 cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa
     5941 acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt tctgcaagtg
     6001 caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag
     6061 cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt gcaggcttag
     6121 ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt atctctgctg
     6181 atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt
     6241 accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg
     6301 ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg tgataaagct
     6361 ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa gagaggacta
     6421 attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac ttcatcgatc
     6481 gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca
     6541 gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg gccaatcgca
     6601 actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg gacaccagag
     6661 tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa tacttcaaag
     6721 gacgcaggac ctccatctaa ttgacgtcca ccatgattgg atacccagat accatctgcc
     6781 cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac gataactgga
     6841 agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg ttttgcagct
     6901 gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg ttcgctatac
     6961 gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc ttcttcacgg
     7021 taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc ttctactgct
     7081 ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg gaaaaactgc
     7141 ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata agtgctgatg
     7201 gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc tttttcatgt
     7261 gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc aattccgaaa
     7321 acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat gattttcttt
     7381 gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc accgcgaata
     7441 tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta ggcaatgttt
     7501 acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga tccttctttc
     7561 atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa catttactct
     7621 cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat ctacttcttg
     7681 gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt cctctatttc
     7741 atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg gtactgttcc
     7801 atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag tggttatagg
     7861 aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag caggcccctt
     7921 tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa aaggcgcgcc
     7981 aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata
     8041 gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat ctatgccgta
     8101 gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc actcgttatt
     8161 tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag acaaatctcc
     8221 tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta ctgcttgctg
     8281 atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc tgtagccgtg
     8341 gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg ccgttttttc
     8401 tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta acgcaaacaa
     8461 actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga ttggttctgt
     8521 catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa tcatatgatc
     8581 gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca agttctgtac
     8641 tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct ccgtcaactt
     8701 ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg acttcgccaa
     8761 cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag atatgattga
     8821 cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca acgaatcctg
     8881 tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc atttcaacaa
     8941 gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt ttgacttcag
     9001 tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc atactttgcg
     9061 cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta tgcaagacat
     9121 accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa ataaaaaaac
     9181 ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac gttgtggcta
     9241 gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat tacgtaaaac
     9301 atcaatccga aaataataga agtttcgatg actactaacg tatctttacg gagttgtttt
     9361 ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa tttcatgaga
     9421 caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga ttacaatatt
     9481 tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact gattttgtgt
     9541 agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc atttacttct
     9601 gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact ttttacttgt
     9661 caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat taatttgaaa
     9721 ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact tgtatataag
     9781 aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt aaaaatttta
     9841 gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat tttccgtgga
     9901 aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat gacgcttcct
     9961 gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc tttcttcaaa
    10021 gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga aaatcatttt
    10081 tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg gagcgtagaa
    10141 caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt ggctgctatt
    10201 gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga tatcgaaaaa
    10261 gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc gaaagtatgt
    10321 gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat tgaaaatttg
    10381 caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg ctttcttttt
    10441 tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa taatacatca
    10501 atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca taggttgtcc
    10561 aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg ctgatggtaa
    10621 agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt tgcaataaag
    10681 ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc atgataccaa
    10741 aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc aatttacggt
    10801 taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc cctgaggata
    10861 caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca tttacaacga
    10921 ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt ttctcctagt
    10981 ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat aattataaca
    11041 gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag cttaaacaat
    11101 gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg gtcataagaa
    11161 ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga aacttaaata
    11221 aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct agcaagcagc
    11281 tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt aatggatcat
    11341 gcgcttgcta ggctttt
//
LOCUS       DACCVZ010000090        11207 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.093, whole genome shotgun sequence.
ACCESSION   DACCVZ010000090 DACCVZ010000000
VERSION     DACCVZ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.093"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            34..771
                     /locus_tag="IVW63_002362"
     CDS             34..771
                     /locus_tag="IVW63_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP7860623.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            785..1600
                     /locus_tag="IVW63_002363"
     CDS             785..1600
                     /locus_tag="IVW63_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAP7860624.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            1613..2260
                     /locus_tag="IVW63_002364"
     CDS             1613..2260
                     /locus_tag="IVW63_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP7860625.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            2276..2932
                     /locus_tag="IVW63_002365"
     CDS             2276..2932
                     /locus_tag="IVW63_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP7860626.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            3094..3915
                     /gene="racE"
                     /locus_tag="IVW63_002366"
     CDS             3094..3915
                     /gene="racE"
                     /locus_tag="IVW63_002366"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAP7860627.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            3918..5273
                     /gene="rph"
                     /locus_tag="IVW63_002367"
     CDS             3918..5273
                     /gene="rph"
                     /locus_tag="IVW63_002367"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAP7860628.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            5274..5792
                     /locus_tag="IVW63_002368"
     CDS             5274..5792
                     /locus_tag="IVW63_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAP7860629.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            5899..6399
                     /locus_tag="IVW63_002369"
     CDS             5899..6399
                     /locus_tag="IVW63_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP7860630.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(6679..7599)
                     /locus_tag="IVW63_002370"
     CDS             complement(6679..7599)
                     /locus_tag="IVW63_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAP7860631.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            7764..8777
                     /locus_tag="IVW63_002371"
     CDS             7764..8777
                     /locus_tag="IVW63_002371"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HAP7860632.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(8887..9642)
                     /gene="fabI"
                     /locus_tag="IVW63_002372"
     CDS             complement(8887..9642)
                     /gene="fabI"
                     /locus_tag="IVW63_002372"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAP7860633.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            9862..10302
                     /gene="fabZ"
                     /locus_tag="IVW63_002373"
     CDS             9862..10302
                     /gene="fabZ"
                     /locus_tag="IVW63_002373"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAP7860634.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(10417..11178)
                     /locus_tag="IVW63_002374"
     CDS             complement(10417..11178)
                     /locus_tag="IVW63_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP7860635.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
BASE COUNT         3584 a         1973 c         2365 g         3285 t
ORIGIN      
        1 aatcttacta aataataatg ggagtgtaat tctatggcaa tgattaaatt tgatcacgtg
       61 gataaatatt atggcaagtt ccacgcatta aaaaatatca atctcgaatt cgagaaagga
      121 gaagttgtcg ttgtcattgg tccttctggt tcaggaaaga gcacgatgct tcgctgtatc
      181 aatggattag agacgatctc ttcaggtaag ctgctgatta atgatactga cttgcatgat
      241 aaaaagacaa aactgacaga agtccgaaaa aacatcggca tggttttcca acatttcaat
      301 ttgtacccaa ataaaactgt tctggaaaac atcaaattag caccaatcaa agtgttgaag
      361 caagaccagg caactgcagt caaaaacgcg gagaaatttt tgaaaactgt caatatgtta
      421 gataagaaag attcttatcc ttccatgtta tccgggggac aacagcaacg ggtggcaatc
      481 gccagaggtt tagcgatgaa tcctgagatg ctgctgtttg atgaacctac ttctgctttg
      541 gatccggaaa tgattggtga tgtattagac gttatgaaaa aattggctca tgacggtatg
      601 tcaatgattg tcgtgacaca tgaaatgggc tttgccaaag aagtggcgga tcgtgttatc
      661 ttcatggctg atggagaagt attggaagac agcagaaatg tgagagactt tttcgaaaat
      721 ccaaatgaag tccgagcaca gcaatttatc agtaaagtta tcaatcattg ataggaggaa
      781 aaagatgcgc aggttaaaaa aaatacgcct gattttcctt ttaggcattg cttttcttgc
      841 actagccgga tgtaaaggaa atgggttggc aaatgaagat attttagagc gaagcaaatc
      901 taccaatgaa atcatctggg gtgtcaagta tgatactcga ttatttggaa tgatggatat
      961 tgagagcaga actgtacaag gatttgatgt agatattgca aaagcaatca ctaaaaagat
     1021 ccttggtgac aatggaaaaa cagaatttgt tgaagtcact tctaaaactc ggattccatt
     1081 attgaaaaac ggaaatatcg atgcaattat tgcaacgatg acgatcacag atgaacgaaa
     1141 aaaacaggtt gacttttcag atgtctattt cgatgctggc caagctttgt tggtaaagaa
     1201 aggaagccaa atcaaaagtg tagatgattt gaatgcttct acaacggttc tagcagtcaa
     1261 aggttctaca tcggctgcga atatccgaca gcatgcacca gatgcaaaaa ttttagaatt
     1321 agaaaactat gcagaagcat ttactgcttt acaatctggt cagggagacg cgatgactac
     1381 ggataatgcg attttgttag ggattgcaga tgaaaatcca gagtatgagt tagttggtgg
     1441 aacgtttact aatgagcctt acgggattgc gatcaacaaa gggcaagaaa acttcttgaa
     1501 agctgttaac caagcgctag aggaaatgca tgcagatggc acatacgata aaatctatca
     1561 aaaatggttt ccaaatgaaa ctgaaggaaa agtagagtaa gggggagagg caatgagcga
     1621 attgatacaa acttatggac caatctttgt cgacgggttc aagatcacat tgttttcgag
     1681 tgtcttagca cttgtgttta gtttgattat cggaacgtta atggcaatct tccaattatc
     1741 aaagaataaa gtagtgagcg ccttagcaaa ggcatatgta gaatttttta gaaacattcc
     1801 attattaatc atcgtgatgt ttttttatgt tgtcgtaccg atttattggt ttaatctaga
     1861 tggattccaa gcaggtacga ttggattaac gatctataca tctgctttta ttgctgaaac
     1921 agtacgttca gggattcaaa ccgtaccaaa aggtcaaaca gaagcaggac tatcttctgg
     1981 ttttacctat tcagaaatca tgcgttatat tgttttaccg caagcattca aaatcgttat
     2041 cccgccatta ggcaaccaat ttatcaacct cgtaaaaaac tcatctattt tagcaatcgt
     2101 agctggttta gatttgatgt atcaaggaga cttgatcgct agtgaaacat tcaatacctt
     2161 cgatacgtat atcatcgttg ggttatttta cttagttatc acgctaccgt tatcttactt
     2221 aatggtttat cttgagaaaa aatgggcggt tcgttcatag aaggagggga aatacatgga
     2281 ttttagcggc gctttttcat ggatgaatat ccgtttttta ttggaaggat taaaggttac
     2341 tgttgaagtt tcattgtttt cgatcatttt tagtttcttg atcggtggtc tgacaggtgt
     2401 gattcgtttt gcgaatatcc ctttcttttc caaaatcctt ggtgtagtga ttgatattat
     2461 acggaatctt ccattattat tgatcatttt cttcacttac tttgccttac ctcaaatcgg
     2521 cattcagatg aacatcttct ggtccgctgt cgcagcatta acgatttttg agtcagctat
     2581 gttgtcggaa attttccgag ctggactcaa tgctgttcca aaaggacaga tggaagcagg
     2641 attatcaacg ggactgactt atgtagaatc gatgcgaacg atcgtgttac cgcaagcatt
     2701 taaatcaatg atcccggcaa ttgtgagcca attgatttca ctgatcaaag atacttcatt
     2761 agcagtaatc atttctttac ctgaactttc tcatcaggca cgtattattt atggacagaa
     2821 caccaattat gtgcttccga tgttcatcat catgacactt atgtacttcg tggtatgtta
     2881 cgcgctttct ctgctttccg gttacttgga aaagagacgg tacagttatt aatagatgat
     2941 tcttttagcg gttgtggcaa actaaagtca caaccgcttt tcctctttcc attcgaaaaa
     3001 aagagatttc gattgtttta agcaagtaag agcacttgaa aattcacgct aaaaagtaca
     3061 caatagggag gatagaattt attgaaaaaa aggatgatac gattgacaga taatcgccct
     3121 atcggattta ttgattcagg tgtcggcggc ttgactgtag taaaagaagc cctgaaacaa
     3181 ttaccgaatg aaaatatttt atttgtagga gacacagcac gctgcccata tggccctaga
     3241 cccgcggaac aggtaatcca gtatacttgg gaaatgacgg attatctggt ggagcaagga
     3301 atcaagatgc tggtgatcgc ctgcaatacc gcaactgcgg tggctttaga agaaatcaaa
     3361 gctgctcttt ctattccagt catcggtgtg atccttcccg gtactagagc ggcagtaaaa
     3421 aaaacacaaa ataaacaagt tggcattatc ggtacgattg gtacggtaaa aagtcaagct
     3481 tatgaaaaag cactgaaaga gaaagtacca gaattgactg tgacaagtct tgcttgtccc
     3541 aaatttgttt cagttgtcga aagtaatgaa taccattcat cggtggcgaa aaaaattgtg
     3601 gcagaaacat tagctccttt aaccactaaa aaaatcgata cattgatttt gggatgcacc
     3661 cattatccat tattacgccc catcattcaa aatgtaatgg gagaaaatgt tcaactgatc
     3721 gattctggag cagaaacagt aggtgaagta tctatgctgt tagattattt caatttgagc
     3781 aattcaccgc aaaatggtcg gacattatgc cagttttata caactggctc tgccaaactt
     3841 ttcgaggaaa tagctgaaga ctggcttgga atcggacact taaatgtaga acatatcgaa
     3901 ttgggaggaa aataaggatg cgtcatgacg ggagaaaagc ccaagagctt cgcaaactgg
     3961 agcttcaaac aaatgttttc aaatatccag aaggatcggt agtgatccgt tttggtgata
     4021 caacagttat ttgttctgca acaatagaaa attctgttcc cccttttttg agagaaacag
     4081 gaacaggatg ggtgacagca gaatatagta tgctgcctcg agcaacgagt acgagaaatc
     4141 gtagagaaag cagcaaaggg aaactttctg gtagaacaat ggaaatccag cgtcttattg
     4201 gtcgttcctt gcgtgcagta gtagacttgg aaaaattagg agaacgtagt atcatcgtag
     4261 actgcgatgt gatccaagcg gatggcggta ctagaacagc aagtatcact ggggcatttg
     4321 tggcattgaa attagccatt gaaaaacttt taagagaaaa agaattgtca gaagatccaa
     4381 taaaagaaca tcttgctgca gttagcgtag gaatcttacc agatgggact tgcgtcacag
     4441 atttggatta ccaagaagat tccgcagcac ttgtagacat gaatcttgta atgacagaat
     4501 ctggaaaatt cgtggagatt caaggaactg gagaagaagc aacgtttgat ggtgaacagt
     4561 tgaatgaaat gctctttttt ggaaaaaacg cgattgaaga tttgatcaaa gagcaaaaac
     4621 atgctttgct aacagagttt gctcaaaatg atgagcggat agaagaaaca aaaacaatca
     4681 tcattgcgac aagaaatcca ggaaaagcag aagagtttcg aaatatgttc aaagaagcgg
     4741 gatatcatgt aaaaacatta cttgactatc ctgaattgcc agatgtggaa gaaactggca
     4801 gcacatttga agaaaatgcc cgattaaaag cagaaacgat tgcacaattg cttgatcagc
     4861 cagtcttagc agatgattca ggtttgaaag tggatgcttt aggcggtatg ccaggaatct
     4921 attctgcacg ttttgcaggg gaacaaaaaa gtgatgcggg gaataacgcc aaattattat
     4981 atgaattgac agatgtgccg gatgaaaaaa gaacagcaca attccattgt acgttagtat
     5041 tcgcggcacc caaaaaagac agccttgtag tagaagcgga atggcccggt cgagtagccc
     5101 gtataccatc tggcgaaaat ggctttgggt atgatccttt atttatccca gaaggtaaga
     5161 aacaaacagc agcagaatta tcgagcgaag aaaaaaacaa gatcagtcat cgggctcaag
     5221 caatgaaaaa attgagtgcc gagtggaaac aatggctgga aggagagaga tagatgcggt
     5281 atttagtagt aagtgataat catggagaca gagatatcct cgttgactta gtagatcgtt
     5341 atcgttctga agtggatatc tttttccatt gtggtgattc ggaattagaa gcttctgacc
     5401 cattatggga tacattccaa gtggttcaag gtaattgtga ttatggacca ggattcgaac
     5461 agaaaaaagt gatccaaact ggtcaggata cagtattcat gactcacggt catttatcga
     5521 atgtccgatt tggtttgaca cagttagcaa tcgaagctcg agctgcaact gccgatatgg
     5581 tgttttttgg tcatacccat caaataggct gtgagatgga tcagaaaatc ctgtttttga
     5641 atcctggtag catttctcag cctagaggcc cgatccaaat cccatcatat gctcttatcg
     5701 aaagtttaga tgaccaaatt tctgttcaat actataaccg tgcccatcag gcagttgaag
     5761 agttggcctt ttctttttcg agagagcgct gaataaaaaa actctaattt ttaataaaaa
     5821 taagctttat tttatgaatt ttgcatccgg tttcggtaaa atagtagtgt tgaatgaaat
     5881 agaaatggag gccatcagat gattggacct atagtaagag aaatgctgct ggaaaatcag
     5941 gaaacgtttt tgattcctgc agaaaatgtg gcaaatgtta tgtatcatca tccattgtcc
     6001 catggtttac ttgtgttatc gaaggtcggt tattccaaaa ttcctgtatt aggaaaagat
     6061 gatcactttg taggactagt aagtttatca gatgtggtca ataaaatgat tgacttgcaa
     6121 acaatcagca tggacccgtt agaaggacta acggttgctg atgtgacaga aacagatgtt
     6181 ccgacaattg atgaaaattg ggaactagaa gaagtactcc atttgttagt cgattcgcct
     6241 tttttaccgg ttgtcacaga agatcggatt ttcaaaggaa tcattacaag aaaagagctg
     6301 cttaaagccg taaacttcat ggtgcatgaa ttagaacgtc gtaatatatt gtctccgaaa
     6361 atcgaagaat taaaagaaca aatcgatatc gtgagctaaa gaacgagaaa ctaaaagata
     6421 atcaaaaaat aagtagaaaa aacagcgtac cagttttgac tttatcttga aaaagaggct
     6481 gggacaaaag cgtttaactc caagaaataa gaaggaattc acgaaaattg cttttcaaat
     6541 ttttgtgaat ttcagcttat ttccgaagga gttgcttctg cttccgccgt ttatacgtgt
     6601 ttagagcgtg ggacaaaagt gttctttact tttgtcccac gctcttttta gtgagattcg
     6661 ttgcatcgtt tgtccaaatt attttccgac agcaattgga ctgttcggaa tcgtgaaacc
     6721 agaagctgtc aattctttga cataggagct caagaactct tcttttaagg catattgttt
     6781 tccgttcaat gcgtagcaga ccgtacgaat cgcaaaattg ctgtttccaa gatccactaa
     6841 tccaaagata gaaggttcag tttggagctc ttcttggtat ttttcagcta atgtacgatt
     6901 tactcgatca atgatctcat agattttgtc atatccttct tcaggaacaa tccgaatatc
     6961 taaaagtact tgcatatttg cacgagagag attgctgatc gtggtgatgt ttcgattcgg
     7021 gatgaaatgg acagtaccat ccgttgcttt cagctgaagg gtacggatac caacagatac
     7081 gacggttcct tcaatcgtta agtttgctag cttgatgtag tccccaacat ccatctgttg
     7141 ttccatgata ataaaaaatc cggtaataac atcactcatg aacccttggg caccaagacc
     7201 gattgccaca cctgcaattc cggcaccagc caaaagtgat ccgatcggca caccgatagc
     7261 agataaaatt gcatagataa aaaagaaacc aagggtataa tgaaaaatag tatttaaaag
     7321 actatgtaaa gtctttaagc ggctctcgtt tagaatggct tttttagaat actgattaaa
     7381 agacttatca atcagatatt ttcccacacg gtgaagaatc caaaaaagga cgatcaaaaa
     7441 aatcagatat aaactttttt ggataaaggc agccaaaatg gcgtcccaat caatcccgtc
     7501 ccaaaaccgc tgaaacgcat ttactttgct gacagcttga tctgtcaatg tctcgccaga
     7561 agagtctgtc gtaccggcag ttgctaataa tgaaaacata aaatcctctt ttctaaaatt
     7621 tgattctttc tgtattgtac caagaagttt tcaaaaaagg aaatagcaaa aataactata
     7681 atgaaggaaa aaagctgaaa ataaaatgac aaataatatg gataatgata aaatgtggag
     7741 aaaataacga aggtggtaag tatatgcaaa tcgattggaa caatctaggt ttttcttata
     7801 tcaaaactcc ttggcgtttt attgccaaat ggaaagacgg acaatgggaa gaaggagaat
     7861 tgacagaaga taattacctg acgattcatg aaggctctcc agcgcttcat tatggtcagc
     7921 aatgttttga aggtctaaaa gcttatcgtc gaaaagacgg caaggtcaat ctctttcgac
     7981 ctgaacaaaa tagtcgacgg atgaatcaaa gtgctagacg attgctgatg ccaatggtcc
     8041 ctgaaaagat gttcgttgat gctgtcaagc aagtggtaaa agcaaatgaa gattttgtgc
     8101 cgccctatgg aacaggcgct acattatact tgcgcccttt actgattggg gtcggtgaaa
     8161 acattggtgt ccatccagct ccagaatatt tatttgtcgt cttctgtacg ccagtaggag
     8221 cgtatttcaa aggtggacta aaaccaacga attttattgt atctgattac gatcgtgctg
     8281 ctcctaaggg gactggtgca gcaaaagtcg gcggaaatta cgcagcgagt ttacttccag
     8341 gaacagaagc aaaagaactg gattactcag attgtgttta tcttgatcca gccacacata
     8401 cgaaaatcga agaagtaggt gcagcaaatt tctttggaat tacaaaagac ggaaaattca
     8461 tcactccgca atcgccctct atcttaccaa gtatcacgaa atattccttg ttgcagttag
     8521 ctgaagaacg actaggactg caagcaattg aaggagatat tttcattgat gatctagatc
     8581 aatttgcaga agctggtgca tgtggtacag cggctgttat ttctccaatc ggtgggattt
     8641 atcacaataa caatcttcat gtattttata gtgaaacgga agtaggacca gtaacaaaac
     8701 ggttgtatga tgaattgaca ggtattcaat ttggagacat agaagcacca gaaggctgga
     8761 ttgaagtcgt ggaataattt caaagtaatg agttgaaaaa aacgtaaaaa gaaaaaatca
     8821 ggaagagact ttaaaaagtt ttttcctgat ttttatatgt tttactttaa agaatgcaac
     8881 aaaagtttat gaaagatgga cacctttgtc aacgtagata atatcaccga tgattccgct
     8941 ggaaagtggg ctgattaaga aagcacaagc attaccgact tcttcgatcg tcacaccttg
     9001 ctgatcaggc gtacgagatt cagataactg gatcagtttt tgatagtctt taacacctgt
     9061 gacagctaat gttttgattg ccccagctga gattccattg acccgaattc ctttaggcga
     9121 gaactcagct gccaaataac ggatagcagc ttcaagagaa gctttcgcaa tacccatcat
     9181 gttataattc gggattgcgc gttctgaacc tagataagtc atgctaacga tcccgctgtt
     9241 tggtgcaaga aacggttgtg cgtattttga tacagcaatt aaagagtagc tgctgatatc
     9301 ttgagctaat tgatagccgt ctctggaaat atcagacaca tttccggaca attcttcttt
     9361 gttggcgtaa gcaactgcat ggacaaggcc gtggatctcc ccagcatatt caccgatggc
     9421 attcattgct ttttcgatgc tttcgtcgct agaaacatca cattctacag tgaatgcttc
     9481 ttcgccgacc aatttgacta atgatttttt cattcgttca ttttggtaag tatagataat
     9541 ttctgcccct tgtttcaaca ttgcttcagc acaaccccaa gcaatgcttt ttttgttagc
     9601 gacgcccata atgacgattt tttttccttc tagaaatgac ataatgactc tcctttgttt
     9661 ctgataaaaa tttgatagtc gtaaaaaaat agagaataat agctaaaata acttcttgat
     9721 ttcttaatta ttagtcaaaa tgttttgatt gtcaaactat tttttcttaa attaaaaaaa
     9781 gattgctaaa tatttaggaa tatgatactt tgatagtcaa agtaatgaaa atggcaattg
     9841 cctgaaagaa ggagtttaat tatgtcttac gtattatctg ctactgaagt aatggaattg
     9901 attcctaatc gttatcctat ttgttatatt gattatgtag atactttaga accaggaaaa
     9961 aagatcgttg cgacaaaaaa tgtaacaatc aatgaagatt ttttccaagg tcactttcct
    10021 gacaatccag tgatgccggg tgcgttgatt ctagaaacac tggcacaagc aggttcgata
    10081 cttatcctaa aatcagaaga gtttctagga aaaagagctt atatcggtgg gatcaataag
    10141 gccaaattcc gtcaaaaagt tgttccagga gatgtgctga aatgtcattt tgaaatcacc
    10201 aaaatgaagg gatcagtcgg tacagcgtta tctgcagcat atgtagatga taaaaaagtc
    10261 tgtgagtgcg agttcacgtt catcgtcaac caaaatgctt gactataaaa cctgatatag
    10321 caaaacaaaa ggaagcttac ttgcttttta tgtaaaaaga agacgcctga atcctagcat
    10381 acgttgtcat ctatgcagga ttcagacgtt atttttttat ttttgttttg cttcttgcag
    10441 tatattgatt ttatcgattt ttacttcttc ttttggtttg tctgaactat ctgtttcgat
    10501 atttgcaata gcatccacga catccattcc ttcaatcact tggccgaaga cagtataatg
    10561 gccatctagt gaaggataac cgccgttttt ataagcgtcg atgattgctt gaggatagtc
    10621 gtcttttaaa agaccatcat gcatatcatc tgtattttga acgataaaga actggctgcc
    10681 gttactgtta ggatcttgtg agcgagccat agataacgca cctcttatat tataaaggtg
    10741 gttgttgatc tctgtttcaa atccttctcc ccaaatgctt tcccctccag tgccatcgcc
    10801 tttaggatcg ccaccttgga tcatgaaatc tttgatgacg cgatggaaag tcagtccgtt
    10861 gtagtaaccg tcttttgcat gtgtcataaa gttttcaacc gcttttggtg cgtgttcggg
    10921 aaataatttg attttgattg tgcctttatt cgtcaccatt tcgaccagat cttcattttc
    10981 ggcgacatct ttcgtcaatt gtggtaattc caatgcgttc aaatcgacgc tactggcagt
    11041 cgtgctttcc gcagtagatg tactttttga actttctgta gacgaactag aagaagtcgt
    11101 gttgtttgca gaacaaccag cagcaaacag caatgctgct gctaaactaa tacttaaaat
    11161 aactttattt ttcttcataa ctgttccttt ccaatttact attttgt
//
LOCUS       DACCVZ010000091        10818 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.094, whole genome shotgun sequence.
ACCESSION   DACCVZ010000091 DACCVZ010000000
VERSION     DACCVZ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.094"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(41..1006)
                     /gene="nrdF"
                     /locus_tag="IVW63_002375"
     CDS             complement(41..1006)
                     /gene="nrdF"
                     /locus_tag="IVW63_002375"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAP7860636.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(1056..3215)
                     /gene="nrdE"
                     /locus_tag="IVW63_002376"
     CDS             complement(1056..3215)
                     /gene="nrdE"
                     /locus_tag="IVW63_002376"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAP7860637.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITTEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            complement(3374..3598)
                     /gene="nrdH"
                     /locus_tag="IVW63_002377"
     CDS             complement(3374..3598)
                     /gene="nrdH"
                     /locus_tag="IVW63_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAP7860638.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            3999..4472
                     /locus_tag="IVW63_002378"
     CDS             3999..4472
                     /locus_tag="IVW63_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAP7860639.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            4469..6601
                     /gene="feoB"
                     /locus_tag="IVW63_002379"
     CDS             4469..6601
                     /gene="feoB"
                     /locus_tag="IVW63_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAP7860640.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            6603..6737
                     /locus_tag="IVW63_002380"
     CDS             6603..6737
                     /locus_tag="IVW63_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAP7860641.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            6831..7475
                     /locus_tag="IVW63_002381"
     CDS             6831..7475
                     /locus_tag="IVW63_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7860642.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            7662..8855
                     /locus_tag="IVW63_002382"
     CDS             7662..8855
                     /locus_tag="IVW63_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP7860643.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            8848..10575
                     /locus_tag="IVW63_002383"
     CDS             8848..10575
                     /locus_tag="IVW63_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP7860644.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
BASE COUNT         3379 a         1934 c         2256 g         3249 t
ORIGIN      
        1 ctttttattt ttcgaaaaat ttttgaatta aaataaatcc ttattccaat ccaatcaaat
       61 aatcgtcgtc tttcatcgct tctacatgac ctaacaaata gccgtttccg acttgtgaga
      121 agaagtcatg gttgcttgtg cctgttgaaa tcccgttcat tacgattggg ttgacatcat
      181 tggcagtatc tggaaagagt ggatccatcc ctaggttcat caatgctttg ttggcattat
      241 agcgtaggaa tgtcttgact tcttctgtcc agccgattgg atcgtataat tcttctgtat
      301 aacgttcttc gttttcgtaa agctcataaa gaagattgta catccagtct tttaacgttt
      361 cttgttctgc ttcaggtaac tcgttgaatc ctaattggaa tttgtaaccg atgtaggttc
      421 catgtacaga ttcatctcgg atgattagtt tgatgatctc tgctacgtta gccaatttgt
      481 tgtttcctaa ataataaaga ggagtataaa aacctgaata gaacaagaat gtttctaaaa
      541 agacgctggc aattttcttt tctagcggtg taccgtgttt gtagatttca ttgatacgct
      601 cagctttttt ttgcagataa ggattcgtat ttgtccagtc aaaaatttct tcgatttctt
      661 ttttcgtatt cagtgtacta aaaatagaag aataactttt ggcatgaacg gattccatga
      721 attgaatatt gttcaaaacg gcttcttcat ggggagtgcg gacatcttta cgcaactgat
      781 ccatgccact ttcagattgg acagtatcta gcagtgtcaa accgccaaat acatgtccta
      841 ctgtatcttt ttccaattga gacaatgtac gccaatcatc taggtcattt gaaagtggga
      901 tacgtgtatc tagccaaaat tgctctgtca gcttctccca agtggattta tcaatgatat
      961 cttcaatttc attccagttt attgcttcat aatatgtttc tgacatgaga atgctccttt
     1021 aattaaaata tgaataagcg aatctatcta tgatattaga tcacgcagct ttcacattga
     1081 ttgcttccga tttcttctgc atcatcagta aaggtacgta cgtaataaat ggatttgatt
     1141 cctttgtgga aagcgtaatg tcttaaaata ttcaaatcac gtgtcgtttg cttcgttgtt
     1201 gtcttccatt cataaatgcc ttctgggatt tcagaacgca tgaataaagt caaactcatg
     1261 ccttgatcga cgtgttgttg tgccgttgca taaacatcga ttactttacg catgtccata
     1321 tcataagcag aagtgtaata cggaatcgtc tcattggata gataaggcgc tgggtaataa
     1381 attttaccga ttttcttctc ttggcgttct tcgatcatgc gagtgatagg atgaatactt
     1441 gcactcgtat cgttgatata tgaaattgag ccatttggtg ctactgccaa gcgattttga
     1501 tgatacagtc catctttcat tactgcttgt ttcaaagcat tccaatcttc agcagttggg
     1561 ataaaaatgc cttcaaacaa tgctttgact ttttctgatt ttggctggaa ttctccagtt
     1621 acgtattttt cgaaataagt gccgtcagca taagctgatt tttcaaaatt atggaaaact
     1681 tgttttcttt cacgagcgat attgttgctt tcaacaagtg tccaataatt caacagcatg
     1741 aagtaaatat ttgtaaagtc taatgaatcc tctgagccat attccatttg ttcttttgca
     1801 agataagtgt gtaagcccat ggcacctaat ccaatcgtat gattcagctt atttccgttt
     1861 tggatcggtg gtacgacatc gatatcagat gcatctgtaa taaatgtcaa tgcacgagtc
     1921 atcgtacgca cagattgacc aaagttaggg ctttgcatca aattcacgat atttgtcgag
     1981 cctaagttac atgagatatc tgttcctaat acttcatatt cctgtttgcc gttaatcaca
     2041 gaaggcgttt gaacttgtaa aatctctgaa cataaattac tcatgatgat cttgccatcg
     2101 attggattct cgcggttcgc tgtatcaata ttgattacgt aaggatagcc agattcttgt
     2161 tgtaattttg agatttcatt ttcaagatca cgcgctttga ttttttgttt gcgaatgttt
     2221 ggatttgcaa ctagatgatc atactcagtt gtaatattta cataagagaa tgggacacca
     2281 tattcttttt cgacactata tggactaaat aaatacatat cttcgttttt acgtgtcaat
     2341 tcataaaatt tatcaggtac gatcacgcca agagaaagag tttttacgcg aatcttttca
     2401 tctgcatttt ctttttttgc tgaaaggaaa gcaataatgt ctggatggaa aacgttcaaa
     2461 taaaccacgc cagctccttg acgctgacct aattgattag aatagctgaa actatcttcg
     2521 aataatttca tgactggaac gacaccactt gcagcaccct catatccttt gataggagcg
     2581 ccggcttcac gaagatttga taaagtaatc cctacgccgc caccaatacg ggacaattgc
     2641 aaagcagagt tgattgagcg cccgatagag ttcatatcgt cagtgacttg agtcaagaaa
     2701 caagacacca attcgccccg acgtttacgt ccagcattca agaaagaagg tgtagctggc
     2761 tgatatcgtt gatggatcat ttcgtctgca agagcaagtg ctaattcttc atccccgttc
     2821 gcaaagtaaa gcgcattgaa ggctactcga tcttcataag tttccagata agcggaaccg
     2881 tcgttggttt tcaacgcata ttgagaataa aatttgtaag cagccataaa agatttgaaa
     2941 gaaaaatgtt gctcgtccaa aaattgatat agcttttcaa taaatgatgg tgaatacaat
     3001 tgaatgaatt ctgcttctat atattcttga tcgatcaagt aattgatttt ttccataata
     3061 gatggaaaag tcatcgtatt tggtttgaca ttttcctcaa aaaaggcaac taaagcttct
     3121 ttatccttat tcaaagggat ttgaccattg actggccgat tgatttcatt attcagcttg
     3181 aaataactga catcttgtaa atttttaaga ctcatacgta cgcccaacct tcatttcgta
     3241 tttgatgatg cttgattgca aatcattgca ttgtttttaa gctttaaaaa aggatttgga
     3301 agtttgcgac aaaaactggt gctgtctcaa gcccttcaaa tccatgtatc acgttttgat
     3361 tcttttagtc atgttagctg gcaagtttac gcaactgatc aggacggaat ccgataactg
     3421 tttctgcatc agaagtaatg acaggaacac tttggaatcc ttgtgctttc aaccagtcta
     3481 ctgcttcagg ctgttcatcg atattgactt cttcaaaagc aatttgattt tctgttaaaa
     3541 accgtttgac catcttacat tgcatacaat tatttttaga aaagattttt acgttcatgg
     3601 tgagtgcctc ctctaacaca ttcttattat ctataataga tagtataaaa ctcttagtaa
     3661 aaaagtcaaa caacaaacac tacatattgt gttgtggaaa ctgtggaata ctaagttttg
     3721 tgtttttgaa aaaagagctg aaaacaagta tcgtgtggga aaatagcaaa tttaatagag
     3781 aaaaaattgt ggaaaactat gaagaaatat ttttttctca tttttatcta tcaatactaa
     3841 agattcgctc ataatatcac aagtataatt gacattctca attaccgaga gtattctatg
     3901 tgagaatgat tctcatttat ttgcgtaaca cgtaagaaaa ttagaacata taatgaatga
     3961 ttttaataca tgatttattt cacaagagag gaatcaatat gcagacctta gcgcaggcaa
     4021 agcagaattt cgtttatcaa gtcgaacgaa tcgaaacaga agaaaaaaca aaacgccatt
     4081 tgcaaaatat cgggatcgtt gccggaagta aaatcgtcgt cgtcaattta tcaggcaaca
     4141 atgccatttt actggtaaaa agtcatcgag tggcagtaag tcgggaaata ctaggtcaaa
     4201 tctttgtcaa taaaaagact gcttcctctg aaagctggac ttctcttgat caattaaaag
     4261 caggagagac tgggatcgtc gtagcaatcc acggacaagg cgcagtgaag cgacggttaa
     4321 tggatatggg attgacgcga aatgtaaaaa tagttatccg aaaactagcc cctctgggag
     4381 atccaatcga actgacagtg cgagggtatg aactgacgtt acgaaagtca gaggccgaac
     4441 taatcttgat acaaagggag gaaaaagaat gaatatcgcg ttagtcggaa atccaaacag
     4501 cgggaaaact agcttgttca atctcttgac tggttcgaat caatatgtag ggaattggcc
     4561 gggcgtaaca gtagaaaaaa aagaaggatc gttgaaaaaa aatccgaaca ttcatattca
     4621 ggacctaccc ggcatctatt ctttgtctcc ttatacacca gaagaagtga ttgcaagaga
     4681 ttatttggtt caggaacagc ctgaactgat catcaacatt attgatgcta ccaatttaga
     4741 acgaaatctt tatttaacta cgcagttatt ggatttagac attcctatga tcattggtct
     4801 gaatatgatg gatgtcatca aaaaagaagg aaaaaaaatc aatctagaaa agctttccta
     4861 tggtcttggt gtaccagttt taccaatcag cgtattgaaa aagcaaggaa tcgaaaaact
     4921 aatcgaaaag attcaggagt ctgcaaaaaa gcggccttct attcctgttc cctgtacata
     4981 tgatccacgt ttagaagcag ctttacatga aattgaagat gtactaggag aacaaagcgg
     5041 caagaaacgc tggtatgcaa tgaaatattt tgaacgagat cagaaggtaa gagaggatta
     5101 cgagatagca gtttctcagc aaaaagagat cgagcaactg atccagttaa cagagaaact
     5161 attggacgac gatagtgaga cgattctggt caatgaacgt tatgaattta ttacccaact
     5221 atgtacactc tgtgttgtgt caaatgattc tttccaatta tcgatgagtg acaaaatcga
     5281 tcagattgca acgaatcgtt ggttagcctt gccgatcttc gcatttgtga tgtggctgat
     5341 ctattatctg gctattcaaa cagtaggaac aatggggaca gattggatca atgacacatt
     5401 gtttggtaca tggttaccag aacatgttgg cagattgtta gctgaatggc aagtagcggg
     5461 atggatgcag gagctgatct tgaacggcat catcgcaggc gtgggagcag tgttaggatt
     5521 tctaccgcaa ttgattatat tgtttttatg cttgagcttt ctggaagact gcggatatat
     5581 ggcgaggatc gcttttgtca tggatcgact tttcaggaaa ttcggtcttt caggaaaatc
     5641 cttcattcct atgctgattg ctacaggatg tggagtgcca ggcgtcatgg ccagtcgcac
     5701 gattgaaaac gagcaagatc gtcgtttgac gatcatggtc acaaccttca tgccttgttc
     5761 tgcaaagttg ccgattattg ccttagtagc aggggccttt tttcctcatc aatcttgggt
     5821 agctccttct gcctattttc ttggtatgac tgcaattatt ttctctggaa tcagcttgaa
     5881 aaaaacacgt ttgtttgctg gagatacagc tccttttatc atggaattgc ccgcatatca
     5941 ttttcctcaa tggtcagcgg tcctaagaca aacctatgac cgcagcaagt cttttgttaa
     6001 aaaagcagga acgattatct ttgtttctag tatcgtgatc tggttcagct cttcttataa
     6061 tttttatgct caacctgttt ctgaagacca aagtatctta gcctttttcg ggcgaatcct
     6121 ggcagttgtt tttcagccgc ttggttgggg aaactggcaa ggaacagtcg cagcgattac
     6181 aggattggtc gctaaagaaa atattattgg cacatttggt attttgtttg gtcatgcgga
     6241 agtatccgaa aatggcagag aaatctggca agtgctacaa cacacatata ctcccgcagc
     6301 agcttattca ttgttagcct tcaatttact ttgtgcgcct tgttttgcgg caattggggc
     6361 tatccatcgg gaaatgaatg ccaagaaatg gacttggatc gccataggct atcaatgcgg
     6421 tttagcttat ttagttagtt ttgtgattta tcagttggga cacttattgg agggtggaca
     6481 ggtagcgtta gggacgtatc ttgctatttt actgatgata ggactcgttt atgttttgtt
     6541 ccgtcagcca aaatccaaga accagtttta tactatattg tcattagaag gagaggaata
     6601 ggatggcgac attcttatta agtgtgttaa tctttggaag tgcaggcgca attgtctata
     6661 ctcgtttaaa atccggtaag aattgtgatg actgtcaaac agcttgccca gtaaaaaagg
     6721 aacagatcaa gcgatgatca gtcgttgcaa gaggctattc tccccttttt tgcttatttt
     6781 gctagagcat agtaagatga gggaaagtaa aaaaagaaag aggaaagaaa atgtctggaa
     6841 agaaaaaaat cgtccgcccg cgctaccagc agattgctgt tgatttagcc gaacgtatcg
     6901 ttgaaaaccg atataaagtg ggtgagaaga tccatgcccg ctcaacactt gccagtacgt
     6961 acaatgcttc tcctgagact acccgcaagg ctatcaatgt gctggtagat cttggaatca
     7021 tggaagtacg gcatggaagt ggggcatttg ttgcttcgaa ggaaaaagca aaagatttcc
     7081 tattgcaata tcaagatgta caatccatcc aagatacaaa agcagaaatc atggcaagtg
     7141 tggagaagca acaagatgag ctgaatcatt tttctcaatt attggatcag ctggtcaatc
     7201 aaacgaagcg aatacataag atgaatcctt tacttccgtt tgaattatct ttatcagaaa
     7261 aagcaatgca tctggaccgt tcaattagcg agttgaatat ctggcaggcg actggcgcca
     7321 cagttatcgc aatttctcat aatgaagaac tgcttgtttc acctggcccc tatgctaaat
     7381 ttacggcagg ggacatcgtt cattttattg gaaatgaata tacactacag cgtatgacaa
     7441 acttttttta cccggagcat cagcttgcag aatgattgtg tgaaatatta aaaaaatatt
     7501 aacttggcta aaccttttat ttacaaagat ttagccaagt ttttttcagt ttggacaagc
     7561 aaatttcttt catttttgac aaagtgacta catgatgtta acatagtgtg gtcacttttt
     7621 tcagaaagaa aaatgaattt acataaaaaa ggagaatttg tttggtaaaa gtagaagtaa
     7681 aacatttaac aaagatattt ggtaaaaaga cacaagccgc tttagatatg atgaatgatc
     7741 accagccgaa aacggagatt ttaaagaaaa ccggtgcaac ggttggtgtg tatgacgtga
     7801 attttgacgt aaaagaagga gaaatcttcg tgatcatggg gctttccggg agtgggaaat
     7861 ccacattgat ccgtctattg aatcgtctga ttgagccaac ttcgggcagt atctatattg
     7921 atggagaaga tgtatcgaag ttaagcaaag aagaattgcg agaagtccgt cgtcataaaa
     7981 tcaatatggt tttccaaaac ttcggtctgt ttccacatcg aacgatcttg gaaaatacag
     8041 aatacgggtt agaagtccgt ggtgtaccta aagaagaacg acaagaaaaa gcagaaaaag
     8101 cattagaaaa ttctagtttg ctttcattta aagaccaata tcctagtcag ttatctggtg
     8161 ggatgcaaca acgggttggc ctagccagag ctttagcaaa tgatcctgag atcttgctga
     8221 tggacgaagc gttctcggct cttgatccgc tgatccggcg agaaatgcaa gacgaattac
     8281 tggacctgca agccaatgtt caaaaaacga ttattttcat tacccatgat ttgaatgaag
     8341 ctttacggat tggggacaga atcgccttga tgaaagacgg cgaaatcatg cagatcggaa
     8401 caggtgaaga aatattgacc aatccagcaa atgattatgt acgtgaattt gtggaagaag
     8461 tcgatcgttc caaagtgctt acggctcaaa acatcatggt acctgcattg acgacgaata
     8521 tcgaatctga tggaccaaac gttgcattga caaggatgcg taatgaagaa gtcagcatgc
     8581 tgatggctgt tgacagaaag agacacctga aagggatcat cactgcagat caagcgttag
     8641 aagctaggaa gcaaaaacgt ccattgatcg acttcctaga tgaaaatgtg acggtgattg
     8701 ggaaagacat ggtggtaagt gatattttca atattattta tgactcaccg actccacttg
     8761 cagttgtaga ggatggaaaa ttaaaaggtg tcgtcatccg aggtagtgtg attgaagcat
     8821 tagcagaaac aagcgaggtg agtgaacatg aataatctat tgaactatca attaccagtg
     8881 gcaaactggg tagaaaatat cacagaatgg tttacgacaa ctttttctgg cctattttca
     8941 tttttacaaa cgattggaca ggcagtgatg tcggggatta caaatttact gttagtgatt
     9001 ccagctcctt tgtttatctt gttattgacg gtagcagctt tctttatttc taagaaacgt
     9061 ccaggactta cgttgttcac attaatcggt ctatggttta tttataacca aggtctatgg
     9121 aatgatttga tgaatactgt cacacttgtt cttttatcta gtgtgatctc gatcatcatt
     9181 ggggtaccat tagggatctt gatggcaaaa agcagtaaag cccaaagtat tatcaaaccg
     9241 atccttgact ttatgcagac aatgccagga ttcgtttatt tgattccagc agttgcattt
     9301 ttcggtatcg ggatggttcc aggggtattt gcctcagtca tctttgctct gccaccaacc
     9361 gttcgtttta cgaatttagg gattcgacaa gttcctaaag aattagtaga agcttctgat
     9421 tcattcggga gcacaagtcg tcaaaaacta ttcaaactag aattgccttt agctaaaagt
     9481 acgatcatgg cagggatcaa tcaaacaaca atgctgtcac tttcaatggt cgttattgcc
     9541 tctatgatcg gtgcacccgg cttaggacgc ggcgtattat cagcattgca aagagcacaa
     9601 gtcgggaatg gatttgtcaa cggggttgca ttagttatct tagcaatcat cattgaccgt
     9661 tttacacagc atttgaacca gccaaacaat aaaaaagctg caggagcaac aacacagaaa
     9721 agtaaaaaac gtcaaggact gatcattggt gctgtagtag tagtgatctt aggtgcgatt
     9781 ggtataggga gtttttcatc tgccaaagaa acaaaacgta tcaacttatc ttatgttgaa
     9841 tgggatacag aagttgcttc aacaaatgta gtcggtgaag tattgaaaca aatgggctat
     9901 gatgtaacga tgacgccatt agataattca atcatgtgga aatctgtttc aaatggcgag
     9961 tcagatgcca tggtttcagc ttggctacct aaaactcatg gttcacaata tgcacaatat
    10021 aaagatcaag tcgaagacct aggtgccaat ttgacaggag caaaagttgg tttagcagtg
    10081 ccagcctaca tggatgtaaa ttcgatcgat gagttaaccg atcaggcagg taagaaaatc
    10141 ataggaatcg agccaggagc tggtgtagtt acggctgctg aaaacacgat ccaaaaatat
    10201 gacaacttga aagactggaa agtagagaca tcttcttcag gagcaatgac cgttgcacta
    10261 ggtcaagcga tcaaaaaaca cgaaccaatt gtagttacag gatggacacc tcattggatg
    10321 tttgccaaat atgatctgaa atacttagaa gatcctgaaa acggaatggg aagcgaagag
    10381 cagatccata cgatggttcg aaaaggattg aaagaagacc agccagaagc ttacaaagta
    10441 ttagacaatt tccattggtc agaaaaagat atggaaaaag ttatgttgga aatcaacaat
    10501 ggaaaagatc cacagcaagc agcaaaagac tggatcaaag agaaccaaga attagtcgaa
    10561 agctggaaaa aataaaaaga cagacacgaa ataaatggag cttccaaaat tggatcaaat
    10621 atccaaattt ggaagctcca tgttcgtctc tatctttttt gtctataaaa aaagagaatg
    10681 cgtagctcat cttcgaaacg ttcaaagacg ccgacaaact attatgaatt tatgggtgcg
    10741 agtcaaagag atcgatcgta ggtatgaaag actaatgtga ttaaagttta ttatgtacga
    10801 agtgcattct caaaaaat
//
LOCUS       DACCVZ010000092        10695 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.095, whole genome shotgun sequence.
ACCESSION   DACCVZ010000092 DACCVZ010000000
VERSION     DACCVZ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.095"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            8..81
                     /locus_tag="IVW63_002384"
     tRNA            8..81
                     /locus_tag="IVW63_002384"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Pro,seq:tgg)
     gene            101..173
                     /locus_tag="IVW63_002385"
     tRNA            101..173
                     /locus_tag="IVW63_002385"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:134..136,aa:Ala,seq:tgc)
     gene            201..274
                     /locus_tag="IVW63_002386"
     tRNA            201..274
                     /locus_tag="IVW63_002386"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:235..237,aa:Met,seq:cat)
     gene            288..361
                     /locus_tag="IVW63_002387"
     tRNA            288..361
                     /locus_tag="IVW63_002387"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Ile,seq:cat)
     gene            385..474
                     /locus_tag="IVW63_002388"
     tRNA            385..474
                     /locus_tag="IVW63_002388"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Ser,seq:tga)
     gene            487..560
                     /locus_tag="IVW63_002389"
     tRNA            487..560
                     /locus_tag="IVW63_002389"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:521..523,aa:Met,seq:cat)
     gene            579..654
                     /locus_tag="IVW63_002390"
     tRNA            579..654
                     /locus_tag="IVW63_002390"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:612..614,aa:Asp,seq:gtc)
     gene            656..726
                     /locus_tag="IVW63_002391"
     tRNA            656..726
                     /locus_tag="IVW63_002391"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:688..690,aa:Gly,seq:tcc)
     gene            740..813
                     /locus_tag="IVW63_002392"
     tRNA            740..813
                     /locus_tag="IVW63_002392"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Ile,seq:gat)
     gene            838..925
                     /locus_tag="IVW63_002393"
     tRNA            838..925
                     /locus_tag="IVW63_002393"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Ser,seq:gct)
     gene            947..1018
                     /locus_tag="IVW63_002394"
     tRNA            947..1018
                     /locus_tag="IVW63_002394"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:980..982,aa:Glu,seq:ttc)
     gene            1041..1130
                     /locus_tag="IVW63_002395"
     tRNA            1041..1130
                     /locus_tag="IVW63_002395"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1077..1079,aa:Ser,seq:tga)
     gene            1143..1216
                     /locus_tag="IVW63_002396"
     tRNA            1143..1216
                     /locus_tag="IVW63_002396"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1177..1179,aa:Met,seq:cat)
     gene            1235..1307
                     /locus_tag="IVW63_002397"
     tRNA            1235..1307
                     /locus_tag="IVW63_002397"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1268..1270,aa:Asp,seq:gtc)
     gene            1311..1383
                     /locus_tag="IVW63_002398"
     tRNA            1311..1383
                     /locus_tag="IVW63_002398"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1344..1346,aa:Phe,seq:gaa)
     gene            1388..1458
                     /locus_tag="IVW63_002399"
     tRNA            1388..1458
                     /locus_tag="IVW63_002399"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1420..1422,aa:Gly,seq:tcc)
     gene            1471..1544
                     /locus_tag="IVW63_002400"
     tRNA            1471..1544
                     /locus_tag="IVW63_002400"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1505..1507,aa:Ile,seq:gat)
     gene            1556..1627
                     /locus_tag="IVW63_002401"
     tRNA            1556..1627
                     /locus_tag="IVW63_002401"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Glu,seq:ttc)
     gene            1893..3086
                     /locus_tag="IVW63_002402"
     CDS             1893..3086
                     /locus_tag="IVW63_002402"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAP7860645.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3216..4688
                     /locus_tag="IVW63_002403"
     CDS             3216..4688
                     /locus_tag="IVW63_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7860646.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4771..5559
                     /locus_tag="IVW63_002404"
     CDS             4771..5559
                     /locus_tag="IVW63_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAP7860647.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMASTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5626..6294)
                     /locus_tag="IVW63_002405"
     CDS             complement(5626..6294)
                     /locus_tag="IVW63_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAP7860648.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            6409..8121
                     /locus_tag="IVW63_002406"
     CDS             6409..8121
                     /locus_tag="IVW63_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860649.1"
                     /translation="MKLILRHAKKYKVSVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQKFVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8124..9896
                     /locus_tag="IVW63_002407"
     CDS             8124..9896
                     /locus_tag="IVW63_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860650.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(9978..>10695)
                     /locus_tag="IVW63_002408"
     CDS             complement(9978..>10695)
                     /locus_tag="IVW63_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7860651.1"
                     /translation="TFTGMIFKFANRRYGLKYNPVNGVSLARKPKTNEEIKKEKDGYL
                     SKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELISLTESDYDGNKITVSGTYD
                     YELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIKNNKDKYIFISKNGNPISIQ
                     AYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPLKAIMDRVGHEDSKTTLKIY
                     THTTKNMQNQLVEKLGKIEI"
BASE COUNT         3120 a         1877 c         2382 g         3316 t
ORIGIN      
        1 aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa ggggtcgcag
       61 gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag ctcagctggg
      121 agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct ccatttcatt
      181 taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc ggttcatacc
      241 cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga cctttagctc
      301 agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacaaggtcc
      361 attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag ggaacggtct
      421 tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc tcctttttca
      481 tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga aggtcgtagg
      541 ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg taggggttaa
      601 catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc gccatgcggg
      661 tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg attctcgtca
      721 cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg cctgataagc
      781 gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat tggttttggg
      841 gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg aaaccggcgc
      901 gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc cgttggtcaa
      961 gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt acgggtcatt
     1021 aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa
     1081 aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct ttttcatatt
     1141 atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt cgtaggttca
     1201 aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg ggttaacatg
     1261 cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt ggctcggtag
     1321 ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt ctgtcccgcg
     1381 ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt gtcgcgagtt
     1441 cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt tagagcgcac
     1501 gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt ttattggccc
     1561 gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc gaatcccgta
     1621 cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga atgattttaa
     1681 aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga cagttctaat
     1741 gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag aaaactgttt
     1801 tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg gagatgcctt
     1861 gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta tttacatcag
     1921 aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat gcaatcttgg
     1981 atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct gtaacaactg
     2041 gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt caaaaagtcg
     2101 tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt gatggagata
     2161 cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa ggagttgatg
     2221 aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt ggtgctggtg
     2281 accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg cctttaccaa
     2341 tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca aatgaattaa
     2401 cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat caaggacaac
     2461 cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta gataatgaaa
     2521 caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct gaattattag
     2581 atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt ggtcctcaag
     2641 gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt tatgctcgtc
     2701 atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct gccagctatg
     2761 ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa gcagaagtac
     2821 agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat actttcggta
     2881 ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc gatcttcggc
     2941 cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa acagctgctt
     3001 acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac aaagtagatg
     3061 cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc caagtggtgg
     3121 ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt atttatctat
     3181 ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca aatgttactt
     3241 tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt acaatcgtaa
     3301 caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg aactgggtat
     3361 tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa cttgcggata
     3421 aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc ggttcgttat
     3481 tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt caagggatgg
     3541 gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat tctattgaaa
     3601 agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt gtttttggac
     3661 cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt tttatcaatg
     3721 tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa ccaaaaatca
     3781 tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc atgcttgtct
     3841 cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt gtttctgctt
     3901 tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa agagctaaag
     3961 atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc aacttggctg
     4021 cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg tggatgcaag
     4081 gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta tcactagtct
     4141 ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact cattgggtct
     4201 tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt atgcctttca
     4261 gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc ttaggtgtga
     4321 ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag cttggtgtag
     4381 caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt tctatttttg
     4441 gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta acaaatgatg
     4501 cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat gcggatattt
     4561 tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta gttggcttgt
     4621 tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt ggtaaaataa
     4681 aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa agttattcaa
     4741 aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa tatttattcg
     4801 aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac aaaaaaggtg
     4861 attggcacca gttcagagca agagacaacg gatatacctg ttttatattt acttcatgga
     4921 atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta tgtagcaaac
     4981 tacggattag ctgtcatcat ggcatctact gatcttggct ggtacacaga tacagtttat
     5041 gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca tgaattattc
     5101 ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat gggcggatat
     5161 ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat ctctctttca
     5221 ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa agcatctttt
     5281 tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga tccgcaatac
     5341 ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat ggcttgtggg
     5401 gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca ggaacaaggc
     5461 ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg ggaccaatgg
     5521 attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct taaaaagata
     5581 gctcctatag agatcacaaa catagtgatc tctataggag cttttttact gctcgttttc
     5641 tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg ttagaaagag
     5701 tgctttttca ttcaattctg catgggactg catactttct ttaaatccct ctaattgatt
     5761 ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat ttccgtccat
     5821 aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa tcaataaatt
     5881 gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac gaacaagtaa
     5941 ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag tattgatttc
     6001 taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca tatactgcag
     6061 caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt ccattgtttc
     6121 agccattttt tgcaagagct gttgtttgtt tttgaaatac caatataaag caggtgcttg
     6181 aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt gtgtttcagc
     6241 caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt ccattttatc
     6301 aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt ctaattttac
     6361 agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat gaaattaatc
     6421 ttacgacatg cgaaaaaata taaagtatct gtttttattt ccttgctgtc cgtagcagtc
     6481 atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga agctattatt
     6541 acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct ggctttgcta
     6601 ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca aggcgtaagt
     6661 gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg aaatatcgaa
     6721 cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca aatccaaaaa
     6781 tttgtgatga tttctttgca atcacttttt cgaattccat tcttatttat tggtgccttc
     6841 attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct tatcgttacg
     6901 gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat gatcattcaa
     6961 aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat tcgtgtagtg
     7021 aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag tgaggactta
     7081 acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc cttcatgctg
     7141 gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt taaagatgat
     7201 cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat tatgatggca
     7261 atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc gctgaagcgg
     7321 attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc agaacaagag
     7381 ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga ggatacagat
     7441 acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat cgtcggggcg
     7501 actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga tccgacagaa
     7561 ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag tttaagacaa
     7621 acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc tcaaaacttg
     7681 cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc tattgctcaa
     7741 gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga agaacgtagc
     7801 agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt tatcggtaat
     7861 ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc tgaaaagctg
     7921 gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat cgcacaaaaa
     7981 attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag attagtcggc
     8041 gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat ctttgaaact
     8101 caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa tttttctatc
     8161 actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg atcattgcta
     8221 cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa ttagctaatt
     8281 acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct gtaatatgga
     8341 aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt attttgttca
     8401 cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac aaattggaaa
     8461 aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt cgttttacca
     8521 gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc atcacgaatg
     8581 ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag ttagcttggg
     8641 ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc cgcaaagcac
     8701 ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat atggatgaaa
     8761 aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg attgaaggat
     8821 tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct tattctggtc
     8881 tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt atctttttcg
     8941 gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc ttagttgtga
     9001 cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca tctggataca
     9061 gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt gatgaaaaag
     9121 atgaagtcaa accagaaaac ggtaaagcat ttgatggtgt tgaaaaaggt cttgcgttgc
     9181 agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc tcgatcaatg
     9241 tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa acgacgatca
     9301 tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc gatggaatag
     9361 atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt ttgcaagaat
     9421 ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg gacgcttcag
     9481 atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc atgacgttag
     9541 aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca ggtcaaaagc
     9601 agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt ttggatgaag
     9661 caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg gatgaagcaa
     9721 tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg aatgcagata
     9781 gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcat gagttattag
     9841 cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa agttaaatta
     9901 aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt ttttataagg
     9961 ggcagaaaag gggcaattta aatttctatt tttcctagtt tttctactag ttgattttgc
    10021 atatttttag ttgtatgagt ataaatcttt aatgttgttt ttgaatcttc atgtcctaca
    10081 cgatccataa tggcttttaa tgggattcct aattctgtaa gtagagaaat gtgggaatgc
    10141 cttaacatgt gagaagaaac ttttttatct aggtttaatt ctttggatac tgctcttaaa
    10201 gattgattat atgcttgaat agatatcggg ttaccatttt tagagatgaa aatgtattta
    10261 tctttattat tcttaattaa tttgttttct tcaattaatt gatctatgat ttctttagca
    10321 ttacttgata attcaatggt tctataagaa cctgtatttt tagttgttgt tttaattttt
    10381 aactcgtaat cataagtacc agaaaccgta attttattac catcataatc agattcagtc
    10441 aaagatatca attcaccata acgtagtcca gttaaaaaca aaaatttagt aattaaagaa
    10501 taacgtgact gttgatgtga acttttttgt ttactagcaa tcatttgaac ttcttctttt
    10561 gataaataac catctttttc tttttttatt tcttcgtttg tcttaggttt tcttgctaaa
    10621 gaaaccccat ttacgggatt atattttaat ccatatcgac ggttggcgaa tttaaaaatc
    10681 attcctgtaa aagtt
//
LOCUS       DACCVZ010000093        10536 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.096, whole genome shotgun sequence.
ACCESSION   DACCVZ010000093 DACCVZ010000000
VERSION     DACCVZ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.096"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            23..646
                     /locus_tag="IVW63_002409"
     CDS             23..646
                     /locus_tag="IVW63_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860652.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="IVW63_002410"
     CDS             1096..2145
                     /locus_tag="IVW63_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7860653.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="IVW63_002411"
     CDS             2142..3023
                     /locus_tag="IVW63_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7860654.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILVICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="IVW63_002412"
     CDS             3026..3796
                     /locus_tag="IVW63_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7860655.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="IVW63_002413"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="IVW63_002413"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAP7860656.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="IVW63_002414"
     CDS             5107..6270
                     /locus_tag="IVW63_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAP7860657.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="IVW63_002415"
     CDS             6387..6797
                     /locus_tag="IVW63_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP7860658.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="IVW63_002416"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="IVW63_002416"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP7860659.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9337..9654
                     /locus_tag="IVW63_002417"
     CDS             9337..9654
                     /locus_tag="IVW63_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860660.1"
                     /translation="MKKVHSFLNYLMGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAY
                     SPTLILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQ
                     YFG"
     gene            9814..10050
                     /locus_tag="IVW63_002418"
     CDS             9814..10050
                     /locus_tag="IVW63_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP7860661.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="IVW63_002419"
     CDS             10047..10445
                     /locus_tag="IVW63_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAP7860662.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3668 a         1768 c         2230 g         2870 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agttatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag tttttt
//
LOCUS       DACCVZ010000094         9897 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.097, whole genome shotgun sequence.
ACCESSION   DACCVZ010000094 DACCVZ010000000
VERSION     DACCVZ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.097"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            254..733
                     /locus_tag="IVW63_002420"
     CDS             254..733
                     /locus_tag="IVW63_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860663.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            766..2994
                     /locus_tag="IVW63_002421"
     CDS             766..2994
                     /locus_tag="IVW63_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAP7860664.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            3123..4766
                     /locus_tag="IVW63_002422"
     CDS             3123..4766
                     /locus_tag="IVW63_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAP7860665.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(4839..5384)
                     /locus_tag="IVW63_002423"
     CDS             complement(4839..5384)
                     /locus_tag="IVW63_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HAP7860666.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(5407..5892)
                     /locus_tag="IVW63_002424"
     CDS             complement(5407..5892)
                     /locus_tag="IVW63_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP7860667.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(5882..6694)
                     /locus_tag="IVW63_002425"
     CDS             complement(5882..6694)
                     /locus_tag="IVW63_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HAP7860668.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(6833..8365)
                     /locus_tag="IVW63_002426"
     CDS             complement(6833..8365)
                     /locus_tag="IVW63_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAP7860669.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            complement(8474..9505)
                     /locus_tag="IVW63_002427"
     CDS             complement(8474..9505)
                     /locus_tag="IVW63_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP7860670.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT         3299 a         1838 c         1906 g         2854 t
ORIGIN      
        1 acaaaaaaga tgttggtgaa gttcaccaac atcaaaaagt atagagccaa aatattccaa
       61 catcatcttg gactttctac atgttactaa tgagcgtgta aaagaacgag atggtgtttt
      121 tatttctatc aatgaagctc tttttctttg caatcctcac ttcaatcctc tataatgtcg
      181 catatagttt agtaaatgag taaactacta atttacttat ttactaaaaa taaaaggatg
      241 aggagttaaa ataatggaaa taccaacaaa tttaaaacat aaaccagtaa tcgttgtaga
      301 agactatgat aaagttgatg gaagaaatgc attaaatatg gatgcaaaag ggctttcact
      361 gggccttgct cagtggaatg atcgtggaaa agtcgatatc tcaggcaagg tatggcgaca
      421 tactggagaa aaatggtcac gacagtcgga agaattacca atcacacgta ttttagattt
      481 agcgatctta gctgcgcaag gaagtttata cttccaagat gcttatcgtt atgaaaaatt
      541 ttatgatcca gaaaatccag tcgtagacat cattggatta caagggaacc gaatgacggt
      601 agaagtagat accaaaaatc caaagatcga tgaagacatc attttgtatt acgatacact
      661 acaaaaagac ggagaactga ttggggaacg attccgtatt ttaaaacgtc ttttagatga
      721 gctaggatat taatagacag agatgatcaa aaggggaaga gaagcatgga gaatttctca
      781 ctaacagaaa accgaacctt ttcacggcta gaaaagcaaa tgatctggaa gaaaccgaaa
      841 agccatcgga caagtgcaga agaatggcgg atcgcctccg aaatcaaagg gaattggcaa
      901 gatcctgaaa tgaaaatcag taacgtactt ttggaaggag atgccgggtc ggggaagaca
      961 caattagcca aagcactatc tgctgatctg caacttccct atacaaaagt gacctgtttt
     1021 gcagatatgg acaaatcaga tgttttcgga gccttattac ctgtagtaga ttctaataag
     1081 gaacaagacc aagaattact agaagctatt taccaaacag atacacttga agctgtactg
     1141 acactgatcc agaaccatta cggcattgat cctttttctg ctaaagaaaa attagcagag
     1201 ctagttcaaa ggatcgaagc tgattatcca gatgcaatcc attacagcta ttacccttct
     1261 gaaatcgttc gagcgattga aaaaggctat ttattagaga ttcaagagcc gactgtcatc
     1321 cgagatgcct ctgttcttgt ggcacttaac tcagcgctcg aaccaaatgg gatgttgaat
     1381 ttaccgacag gaatcattcg tcgccatcca gattgcgtca ttgtgatcac tacaaatcga
     1441 aattaccaag gaaatcgccc attaaatgaa tctttaagag atcggatgca acatgcggaa
     1501 aaaatggatc ttcctgcctt agaagtcatg gcagaacgtg cgatggcgaa aactatgatc
     1561 caaaaacaag aacttctctt aaagatggca gagattatcc gtttgttgga tgaaactgca
     1621 aaagctaacg ccatcaaagg tgtagcagga atgcgttctt atttttattg ggcaaatacc
     1681 tataagcaag gacaagattt actccagtcg atttatccaa aagttttgta taaattatcc
     1741 actgattcag atgaattggc aattcttgaa caagctttgt ctgacagtgg attgctactg
     1801 gaacttcagg acatattgag aaaagaaaaa tggggtcatc ctcaatctga gcatacaaaa
     1861 gaaagaacca ttagcgccga agaagcaaat gaacgaaaca tcactgaaaa tgctgaagaa
     1921 attctgcgct tagatgaaaa gaaatcgttg tctgctgaag aaccaaatga gggagaagag
     1981 aaacaagaag aaacaataga aaaaaacgag attcctcctc aaatgcaaaa agaacgcagt
     2041 agcgatatcg aaggaaaaaa tcaaaaagaa caacaaacag gagatgattc tcaagaaatg
     2101 tctgcttctg acatggaagc acatgataag gaaatcaaga agcaactgaa taaagaagcg
     2161 cgacaaatca tgaaggaaac gattcatgaa aaagaaggtc tcatcgttca ccgaccagct
     2221 ttccaaggaa aaacgccgga agcacgtgag ctacacatgc aagtaatgcc aatagtagaa
     2281 tcacttagcc ggcaaatttt agagttactg gataatgaac aaacagagac gtaccaaaaa
     2341 ggaaaatacg aaggtcagcg gttcaatgca agcaaagtag catatggtga tttgagaaat
     2401 tttgacaaaa agaacccgcc acatgagcaa ccttctttag cggtagctgt acggatcgat
     2461 gaatctgggt caatgatacg ggatgatcgg atcgaagcgg caaaaaaagc agcgattgcc
     2521 attgccgaat tttctaagaa agtcgatatc ccattgttga tttacggaga tacagcagac
     2581 cgttcgtcaa gagaaaagac ttctttgttt tcttataaag aatttgaaga cggatttcaa
     2641 tggttaaatg aaaaattagt cactatgaaa ccaaggcaaa acaatcgtga tggtgctgca
     2701 cttcgtttag cagcagaaaa attaaacaga caatccgcaa caaccaaact gttgcttaat
     2761 attagtgacg gtcagccaaa agcgttgccg gattatacag gcaaaaaagc aaaagaagat
     2821 atccagtctg ttttgaaaga atatgaacgt caaggaatcc tatttgtctc cgcagctatt
     2881 ggccaagaca aagaagaaat caagtcgatc tacggtgaaa gtcgttttgt agatattact
     2941 gacttgaatg aatttcccaa gcaaatgatt caactgattg cccgctatct atgataaaat
     3001 aaagctcaac gaacgcactt agcagattcg ttgagctttt cgtttctagt taccggtaac
     3061 aaggatactt ctaaaataga atcggttata atcaagaggg accgttaaag gagtgaaacg
     3121 atatgataca agaacaaaaa tggtggaaag aagcagtagg ctatcaaatc tatcctgcta
     3181 gtttcaaaga tagcaatggc gatggtcaag gagacatcaa tgggatccgt gaaaaactta
     3241 attatttgaa agatcttggt atcggcttta tctggatcaa tccgatctat caatctccat
     3301 ttgtcgataa tggttatgac gtaagtgact atcaagatat agaagagaga ttcggaacga
     3361 tggaagattt tgatttattg ctaaaagaag cacatgaatt agggatcaaa gtgattatgg
     3421 atcttgtcat caaccatagt tcggatcagc atcaatggtt tgaagaatcg aaaaaatcta
     3481 aagaaagccc gtatcgcgat tattacattt gggtcgacgg ggtagatggc aaagaaccga
     3541 ataattggac atcgattttc ggcggttctg cttgggagta ttctcatgaa actggacagt
     3601 attatctgca tgtttttgca aaagaacaac cagacttaaa ttgggaaagc gagaaattga
     3661 aagaagaact attcaatatg atccgatggt ggttggataa agggatagat ggatttcgtt
     3721 tagatgcgat ttctcatgta aaaaaagatg aatattcagt aaaagccaca gagaaccctt
     3781 tctcaccctt tcaaaatgtc tcaggaatcg aagaacattt gaccgatttg aaacatgttt
     3841 ttgaagagta cgatatcatg actgtcggag aagcaagtgg tgtcactgca gaagaaggac
     3901 cacaatgggt agggaaagac ggttatttcg atatgatatt cgaatttgat catatccata
     3961 tctggcagca agaaaaagaa gggcaattag atgtccttaa attgaaacat gcattaagcg
     4021 cttggcaaac ttcattggat ggtatcggat ggaacgcttt atatatggaa aaccatgatg
     4081 ttcctcgtgc cgtttcagtg tttggagata ctcgtcccga tttttgggct atgtctgcaa
     4141 aagcaatcgc tatgatgtat ttctttttgc aaggtacgcc atttatttat caaggacagg
     4201 aaatcggaat gacgaatatg ccctttgaat cgatcgatca agttgatgca gtagattcga
     4261 aaagacttta taaaaggctg cttgcggaag gtaagacaag agaagaagca ttggatatca
     4321 ttcgtgaaac aacgagagac aacagcagga cacccatgca atggacttcg gaacaatatg
     4381 ctggtttttc tacacatgaa ccttggctga tcactaatcc aaataccaaa acgatcaatg
     4441 tagaacaaca agaatatgaa ccagagtcgg tcctgcaatt ctataagaac atgatccgca
     4501 ttagacaaac caataaaggt ctgatatacg gttcttataa agaatatctt catgaacatc
     4561 cacaacttta tgtctatgaa agatatttag aagatgaaca atatcttatt atggtaaact
     4621 taacagaatc acttgctgac tatgaacttc caaaagaagc agatcagtcc tggacattac
     4681 tcttgtcaaa ttcctctagc ggagaatttg aagctaaagg catactagca ccttatgaag
     4741 ctcggttata taaaacaaac aagtaaaact tcctcgttaa agttcattag ttggactttg
     4801 cgaggaagtt tttcagattg ctctgtcaat tactcatttc aataattcgc tctaggacca
     4861 ccgatatatt taggacgaga gcgaagggct gtcacgtgag cttgtccaag ggttttcaaa
     4921 cgaggtctga caggtacttg gacatgcttg atatgcatac cgattgatgt gtcaccgata
     4981 tcgataccgg cttgtccaac tacgtgttcc acttcgacag gatcattgaa ctggtcaaaa
     5041 gcagcaacag aacaagcacc tccagcatgt agtgcaggaa caacagagac aatttcgaaa
     5101 ttttttgctt ctgccactgt tcgttctact actaatgctc ggttcaaatg ttcacaacct
     5161 tggacagcta gcgcaatttc tttaggatcc aacaactctt ttaacgtacg gatgatccat
     5221 tgaccaactt ccgcactgga attttttcca atatgtcctc caacgacttc gcttgtgctg
     5281 catcctaaaa caaaaagatc accttttttc aagtgtgcct cagccaatat gtcattaact
     5341 atttcagtca attggtcttt taattctttt tctgacaact tcattttcta aaaccttctt
     5401 tttcaattaa tattgcttcc gtgcttgaat acgttgaaga cttgcagtta taggaaaggc
     5461 aagtcccatt ccaatcagat tttggaagat gtttcctggt atagaagcca ctccagccgg
     5521 ccaatcatat aaaatccaac cggcgatacc atagccgatg atcataacta agcttcctaa
     5581 taaaagccct aatccccaca tacgagtaga agatttgctg aaagaaccag caacatatcc
     5641 ttgtaacccg tggatcacta atgaaaaaac tgcccactgc ggatatcctg aaatcaaatc
     5701 gatcaataga ccactggaag caccaacaac taatccaccc gttggaccat aaagaaaagc
     5761 agcggtatag atcccggcct cgcataatgt cacaaatcca ttcgtagccg gtacagggat
     5821 caaaattgtt aatgaaaggg caactgtcaa cgcaatcagc atagcataga tcgttaattg
     5881 cttagttttc atttctcatt cctccttttt gaataccgcc agaccagaca cttccggtat
     5941 gatcgttcat cagcacgcca ttagaaatac aatgggcaac aaatttttta ctttctgcta
     6001 ctgctttggt aaaatctgcc cctaacacaa gattcgctgt tattgcagaa gaaaaggcac
     6061 aaccggcccc gtttactgtt gtagtgtcga tttttttatg agaaaatacc tcataatgat
     6121 caattgaata gagaagatcc acagcttcat ctccagccat ccttgtgccg cctttgatca
     6181 caatgttttt tgttcctgaa gcagtgagtt ctttagcgag atggatcatt tctgttaacg
     6241 aagagggaag agcttgacca gaaagtaaag cagcttctgc caaattaggc gtaatcatcg
     6301 taacaagtgg aaaaagttct tcgatgagct gcgaaatata caattgattg atcacagctt
     6361 cagtttcttt gaatgccaaa acagggtcta aaatgattgg gatattttgt tttgttttta
     6421 tgaagtctcg aacaaccatg attgcttcac ttgaattcaa taacccaatt ttgataccat
     6481 ctaatgaagt cattttatca atcgaaacta actgtcgttt aagcaattcc aaagatatag
     6541 attccagcat aaatcgctca ttaatatcta gtgcccctat agaagtcaag gcgcttagtc
     6601 cgaatagacc aaaattctca aaagttttta aatctgtttg gattcctcca ccagcaaatg
     6661 gatcagaacc gccaattgtc aagattcttt tcataacatt ttcctccatg aataagagta
     6721 taacgaaatt ttcaaaaaag aaaaacagcc aattggcata tttttatctc atccaattta
     6781 aaaaaacaaa aagaaaagaa agaccaaaat ggatctttct ttccttaaat agttaggact
     6841 tttgtgattt taattctttc tcgatttgaa gccgttgcac tttcattgta gctgttcgcg
     6901 ggattgcatc aaaatcacgg atgataggga cgttcaagcg aggaagttca tggacttgct
     6961 cccaccatcg attccaatcc atttctttat caggagctaa agcaataatc ggttgtggag
     7021 aatgattttt atcccttaca atcactactt ctgccaaaaa atctaacgaa tctaataaaa
     7081 agtcttcaat agctaatgta ctattgatcg tttcgatcaa atccacttgc cgatctttca
     7141 aaaataggtg gccatgctta tccataaaac cgtaatctcc gctatcccac caatcgccat
     7201 aaacattttc ctggaaccgt gcatcttcct tgtaataagt caaagcccgt cctttagaca
     7261 gtaattgtat atgaccatct gtgttttcag gtaggacatt cccaactgaa tctgtaatcc
     7321 gagcgcttgt catgtcttcc agtccaacgc ccatatctct tgcatcactt gttttcaaac
     7381 tctctagtgt atgagcctta agaatcattg gtccgcattc actttggcca tatacttgaa
     7441 gaaataccgc atcctgtgcc atcgacgttc gcaaaaatgt cttcattgtc tggttgttta
     7501 tagcatcaaa agtggagtga tagtatcgga tacccgaaaa agcttctgga tgctccttag
     7561 cagtaaaacg ccactgaaca aagttattcg gatgggtctc tagtgcaatt ggccggtgag
     7621 cttccaacat atgaacaact tttgaacttt gtgcgtttgc taaaggcatc ataggaaatc
     7681 ccatggacat caaagaagag ataccaatat tgaatctgga atgcactgga gagatgtgaa
     7741 aagcgattaa tttcttttcc gaaatttttg tgaaaactgt tttttgccat ttcgtccgcc
     7801 atcccataga atgagcagaa tgacaaataa gtttagggat accagttgta ccagaagtat
     7861 gggtcatata agaaatttca tttttgtcta aaaatgattg agaaacagac aaagcaggtt
     7921 gttccattaa ataaagaata ggaatctgtt ttgattttgt tccatttgaa atttctctca
     7981 ctcgcttttt tgtctcatca tcaaataaaa tgaaagggtc ttctaaacga tcgataaata
     8041 cttccattgt tgttgttggt agatgataag aagtcatgac aggcactgca ccaaggtaag
     8101 acacagaaac agctagaagg tatgtgtcaa aagcggaact cttataaata ataactttgt
     8161 ctccggattt cactccaaga tgagccaatt gataagcccg tttcaacaca ctttcgcagc
     8221 attttttgta agttgtttca agtcctaatt ctgggaaagc tgaaagtggc tcatcaaaga
     8281 taatcggggt ctcggaaaag ttagctgcag cttcttgaaa attcgtaaat aagttcaaag
     8341 gggaatacgt tatggtctcc atcattcaca ctccattatc ttttgttaag taatatacaa
     8401 attcaagata atcgtaacat aatcctttat ataataacat agtttattgt gaaaaaaaga
     8461 tcatacattt gttttatatg gaagaaaccc gaacgaatgc cgctaattcg tgataagaaa
     8521 aatcaaccat cttttcccag atatcttgaa aagaatggga tgagaggtat cgattaccac
     8581 ataaataatt taccgcgtca gcatcatcta aatatagttc tgcataataa cgatatgttt
     8641 ttctgcatag ttctggcgat acgtttttat atactgtaat tttgctcaaa atttggcgaa
     8701 tagtccgagg agaaatttgc tgatcatgtg aggaacgaaa aacaaaagaa ttttcgtccg
     8761 tattttgtgc tgttaactta aaatagttct ccagaaatgg catcgcttct tttggtattg
     8821 gtactttatt cagtctgttt tcttttctat tcagattaag aatctgcttg gtcaaagata
     8881 catctttacg tttaagttct actacttcat ggatctttaa tccgcaatac agaagaatgg
     8941 cagtaattgc aaggttcctc ggtctattct tttcttcaaa gctagcttct ctgcttgttt
     9001 gaaagccttc aatcgggata aacaaatgct caaaatcttt gaaaagttct gcatcgatat
     9061 atcgcggagc tgctttggtt gtttccggta aacttgtacc caaaagagaa atctcttctt
     9121 caatcagtcc tttttgatac aaaaatcgta aaaaatgatt taatgaatat tgcttccttg
     9181 aaatcccgta atagctattt tcaaacaatt gctccgtttc ttggttcgct gtagtttgga
     9241 acgaacgagt atgtcgatag attttagcta agaaattctg ataatcttgt ttttctaaat
     9301 ggataatcag ctgatcatcc acttcttcag aaaatacttt tctcaaataa tcagtaaaca
     9361 gatgaaaatc ttttgcgtat tcatagcgac tgcctaatga aagggaagaa cgattttctt
     9421 ctaaaaactg ttgaaagacg gaagggagca agtgtgtacg ttgctttaac ttttcttgca
     9481 gttgttttct agttttgctg tccattacaa attccctcca atagtgttca ttttctatat
     9541 tttaccgcat ttcatcaaat gaagatagac agtttgtctt gatcttagga agcaaatttt
     9601 taactaagta ctagctaaaa gatatgaagt aagaagatac atttttagtt attttattag
     9661 tgcagtcatt cttttgatct tttaattgat ttatcctctt tttagctatg tggttacttc
     9721 atgagcaatg aaatggattt ggttcgttct aatggcagga ggctctttct tttatttccg
     9781 aaaaattaga aaacattttt tcagaatcga ttggctctcc atttattcaa taatggtttg
     9841 tctaacgata ttgttgggat aattcttaaa gaagtattag aaatagttgg tacttca
//
LOCUS       DACCVZ010000095         9888 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.098, whole genome shotgun sequence.
ACCESSION   DACCVZ010000095 DACCVZ010000000
VERSION     DACCVZ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.098"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(109..2229)
                     /locus_tag="IVW63_002428"
     CDS             complement(109..2229)
                     /locus_tag="IVW63_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP7860671.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2459..3637
                     /locus_tag="IVW63_002429"
     CDS             2459..3637
                     /locus_tag="IVW63_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HAP7860672.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3653..4411
                     /gene="aroD"
                     /locus_tag="IVW63_002430"
     CDS             3653..4411
                     /gene="aroD"
                     /locus_tag="IVW63_002430"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAP7860673.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4434..4919
                     /gene="ybaK"
                     /locus_tag="IVW63_002431"
     CDS             4434..4919
                     /gene="ybaK"
                     /locus_tag="IVW63_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAP7860674.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4990..6243)
                     /locus_tag="IVW63_002432"
     CDS             complement(4990..6243)
                     /locus_tag="IVW63_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP7860675.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6360..7709
                     /gene="gdhA"
                     /locus_tag="IVW63_002433"
     CDS             6360..7709
                     /gene="gdhA"
                     /locus_tag="IVW63_002433"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAP7860676.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7821..9167
                     /locus_tag="IVW63_002434"
     CDS             7821..9167
                     /locus_tag="IVW63_002434"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAP7860677.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9475..9861)
                     /locus_tag="IVW63_002435"
     CDS             complement(9475..9861)
                     /locus_tag="IVW63_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP7860678.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3149 a         1800 c         2025 g         2914 t
ORIGIN      
        1 ctgagccaga atgaggttca ttctgaccca gatttgattt tgtacaaccc atcagtcctt
       61 attgacaaag agcctaattt tgtcgctgct ccttttaaat ttattttatc attcggaaga
      121 acttgtggtc gttccgtgaa gttcttggta cgtttgcgtt ttataaagat caacagttga
      181 ttgtccgttg tgttcactaa agacactagt tgacttgtca ccaagagatt tttcagcttc
      241 ttttaatttc tctaagccat tcttgtagtc ataatcactg gtatcaattg ggtctaatcc
      301 actattcgta tagaaccgaa gaagatcacc attattgatt tggtcagaaa cagctaactg
      361 tttatcaact ttttctttca gtgaatcaat ttcattctgt acttcctcag taggttcagt
      421 aatagcttca ccagtttcgt tactatagat cgtaccaccg tagtaagtat attttggtgt
      481 aacaaaatca ccatcacgga aagaaacaag ctgttcatga tctttcgaga atagatcttg
      541 tcctaactga atataatttt ttgtatctac acctagtaag tgaagtaatg taggcaaggc
      601 atcaacttgt ccgccgtaag tgtgattgat tccgccctgt gtttgtccag ggatatggat
      661 catataaggg acacgctgca tttgtgcatt gtcgtagttt gtccaagtag aacttgtttt
      721 tccaactaat tcagctagat ttttatttct tgaattcgag acaccgtaat ggtcaccgta
      781 aaggacgatg actgaattat catacaagcc gctttctttc aaataattga agaattcttg
      841 tacggcggta tctaaataat tggctgtcgc aaagtaaccg ttgatcgttt catcatttgt
      901 attggctaac gggaatcctg cttcgtcatt ggtgaatttt gaataaggat aatggttaga
      961 tacagcaatg aattttgaat aaaatggttg ttgcagacgt tccaagtatt gtacggattg
     1021 ttggaaaaat ggtttatcat gcaacccgta ttggaacgaa ttgtcatcat taacatcata
     1081 ataagaagaa tcaaagaaat aatcatatcc taaattcttg tatgtctcgt ttcgattcca
     1141 gaatgtacca gcgttcccat ggaataccgc actagtgtaa ccttgtgttt gacttaaaat
     1201 atcaggtgca gcttggaaag tattttttcc gcctaattgt gtgaacaagg agccttgatt
     1261 caagccaaac aatgaatttt ccatcagcgt ttccgcatcg cttgtttttc ctgcttttac
     1321 ttgatggaaa aagttgtcaa aactgaacgt gctgttgctg tggtaaagac tattgatgaa
     1381 aggtgtaact tcatgctgga gaccattctc atctgtcaat ttataatcga tcaggaattg
     1441 ctggaagctt tctaaatgga tataaatcac attttttcct ctagcgagcc cgaacaaatc
     1501 gtcatttggt gctgcataat gttcttttac ataattttct acttctttca tatcattggg
     1561 acttgcttct gcccgcactt ggtttgtctg gtaagtttga acaccgtcat aaaccatgaa
     1621 agcattcaag ccaagatatt tgaccaaata atcacgagag aatgttcgag tcagcaattc
     1681 tggacgatca gcttccgcca taaaaagatt tcctgagaaa atcataactg ctaatgtaga
     1741 gatcgcaaaa gccattcttg ctcggatcgg gcgagggtcc aacttgattt tttttgcaat
     1801 cagcagaaca gtcaagataa taaaatcgat ccaatagatc acatcatatg ggcgaaacag
     1861 tcgaatggca ctttctccca gaccactcgc tactttccca gcacctaaaa tcgtgttgat
     1921 cgtaatgaag tccgtgaatt ctcgataata agtgacattc gaaaaaacaa gcaatgtcaa
     1981 aagaaaataa atgaccatca tcgtgatata agcaactcta gggcgtctga tataaagagc
     2041 aattccaagt aataacaatg tagttgcaat agggttgata aacaagataa agtattgaat
     2101 gccactttcg attccgagat ggaaatcaac taaataggca aaaatcgttt tcaaccaaag
     2161 taaaacgact agtaaagaaa aaaatccgag cctcttattc aaaaaggcag gtgtttttat
     2221 acatttcaag ataatcttcc tttctgcact tcttaatcac agaagtgtcc tgaaaccatg
     2281 ttacacagct cacttattct catttatttt actagtatga caatatagtg tcaattgaaa
     2341 ccagaagttt atgctgtttc attaaggttt tctttaagct tcatgaaaaa atgagcagta
     2401 agacaagtcc tatgtttttt gttatacttg ggaagagaaa gctaaagcag gtgaaggaat
     2461 gaaagtaaaa gtaaaaaaaa gagcaagcaa tcgattgaaa aaaggatatc cactgatcca
     2521 aaaagaagac cttgctcatc cccaaaaaga aaccacgcaa tgggtggaat tagttgattc
     2581 gcaaaaccaa tttatcgcaa aaggatatct aggaaagcag aataagggaa tcggttgggt
     2641 attgagccag cagaacatcc catttgatca atcttttttt gaagaatttt ttgtgaagtc
     2701 aaaagaaaaa agaactttct ttttttcaga tgattctact accgcttttc gtatattcaa
     2761 tggagaagga gacgggatcg gcggtctgat tgttgattat tatgcaggtt atgctgtttt
     2821 ttcttggtat aacgaaacgt tatatgcaca tcgtgaatta ttgattcaag cttttcgtga
     2881 aatctacccg gaaatcatag gaggctatga gaaaattcga tttgaatcag taaatctgcc
     2941 tgagagccag ttcatttacg gaaaagaggc accggaaccc ttgatcgtaa aagaaaacgg
     3001 agtaaaattt gccgtttatt taaatgaagg attaatgact gggatctttt tagaccaaaa
     3061 agaagtacgg ggatcattag cagaaggttt cgcttctggg aaaacagttt tgaacatgtt
     3121 tagttatacc ggcgcctttt ctgttgctgc cgcaatggga ggggcaatcg aaacaacaag
     3181 tgtcgatcta gcaaaacgca gtttaaaaaa aacacaggaa cagtttgaag tgaatggttt
     3241 ggatgtcgat cagcaaaaaa tcattgttat ggacgtattc gagtatttca aatacgccaa
     3301 aagaaaacaa tttttatatg acatgattgt attggatcca ccaagttttg ccagaaataa
     3361 gaaaaaagtc tttcgcgtag caaaagatta tggggaactg gtcaaggata gtctggatat
     3421 tttagcagaa gacgggatac ttattgcgtc tacaaatgct gcgaatgtct cgatagaaca
     3481 attccaaaca atgattgaag aggaattcca tgccaaaaat gtttcttttg aacaacttgc
     3541 tttatatcgt ctgccaaaag atttccagac gacggatacc tttttagaag gcaattatct
     3601 gaaagtgttt gtttatcaaa ttaaaaataa ccattagaag gagcgatgca gaatggttcg
     3661 ggtaaaggga ttgaatatag gaagcggtag accaaagatt tgtgcgcctc ttatcggggc
     3721 cgtccgagag gaagtattac gtgaagcagt tcttgcacgt gaagcagggg ccgatttagt
     3781 cgaatggcga gtcgatcatt atcgtgaagt tttttctttt gatgaagtag cagaaacatt
     3841 ggttcttatc catgagatgc ttgatggact gccgttatta tttacgtttc gtaccttagc
     3901 tgaaggcgga gaacaagaca tatcgatccg tcagtatcgc gacctttatg aacatgtgat
     3961 acacacagga ttagtagata tggtcgatat cgagttgttc aaagtagaaa gtctaggaaa
     4021 aagactgata gaggaaatca agtctttaaa cattccttta attatcagta gtcatgattt
     4081 taaagaaaca ccagcagacc ctgtcttgct ttaccgattg aatgttatgg aacattttgg
     4141 agccgatatc ggaaaactgg cagtaactcc caataatgaa cgagatgttt tgcggttgat
     4201 ggagttgact agacgggcaa atgcttttgt ctccatgcct attattacga tgtccatggg
     4261 aaatcttggt aaaatttctc gtctggttgg cggaacgacg ggttccgtta tgacatttgg
     4321 ttccttaagc agcgattcta cttctgctcc aggacaatta ccggtcaaag cattgaagca
     4381 aattattcaa ttattaaatg aaccgttgta gaacaagttt gaggtgatat tttttggcaa
     4441 agaaaaaaat agtaaaaacg aatgcaatcc gtatggtcga acaaaaaaag attccctata
     4501 cagagcacga atatgagtgg gacgaaagcc acctaagtgc gtcatcggtc gctgaacagc
     4561 ttccagaaag ccaatctcgt atatttaaaa cactggttgc tgtgggcaat gtgacggggc
     4621 ctcttgttgc tgtgataccg ggagaagccg aattgaatct aaaaaaatta gcaaaagttt
     4681 cagggaataa aaaagtagaa atgctccatt taaaagattt ggaagcaacg accggataca
     4741 tacgtggtgg ctgctcgcct ataggtatga aaaaactatt tcctacttat ttagatcaaa
     4801 ttgcagaaag ctatgaacaa atcattgtct cggctggcag aagagggcta cagatggagt
     4861 tagcacctca agatatctgt gcattaacga gcggacaatt tgcagatata aaacaataaa
     4921 tcatacgtat aaaagaaaga aggaggccgg gatgttgttt gtccagtctc cttctttctt
     4981 ttttatacat tatgctcttt gcccggcatt cattcctgct acatgccctg tagcgaaagc
     5041 cgctgtgata ttaaagccgc cagtataacc attgacatcc agtaattctc ccgcaaaata
     5101 cagaccatca atgattttac tctccaatgt tttaggataa atttccttta gagaaacccc
     5161 tccgccagtt acaaatgatt tctcaatagg aaaagttttg ttgattgata gcttaaactc
     5221 tttgcatagt tgaacaaaat cttgaatttg tttttgagag gcttgttgtc ctgtcagatg
     5281 atccatttca agccgctcaa gaaagaaaac taacaatcgc tcaggcaata taccatgcca
     5341 agcattgacc aagttctttt tggttgcttt acttttttct gtcaatatat gaataagctc
     5401 ttgtttggtt tgtgtaggga aacaatccag agaaagtgtc actggttctc ccgttttctc
     5461 taattcttta ttgacaaaac ttgaacaacg cagtgcagcc ggaccagaaa taccgaaatg
     5521 ggtgaaaagt aaatccatcg tatgttcagt caatacacga ccttttttat ttaaaacgcg
     5581 taaagtgatg tcttgtaaag aaagcccttg aagtgttttc tcctgaatat acggttcatc
     5641 cgatatcaag ggggactctg tcgcataaag aggcgtcacc gtgtgaccca ctcgcttcac
     5701 gatcttgtac ccatctccag tagaaccagt agatggataa gtccgtccac cagttgttaa
     5761 gataatggca ggagcatgga actcttcgaa ttccgtgcgt ataccgtaaa ttttatgttc
     5821 tttgtggatc aatttctcta ctcgagtaga gaatagaagc gtcacatcta gttctttcag
     5881 acgattgagc aatgcttcga taatcgtttt tgatttattt gttacaggaa acatccgtcc
     5941 atgatcctct tcttttaaat gtacgccttg tgattcaaag aagttcatga tatcgaaatt
     6001 attccattgc gcaaacgtac tatataaaaa ctttccattt ccaggaatat gtgcaatcaa
     6061 atcatcaaca ggacgattgt tcgtaacatt gcaccgacca ccacctgtca tcagtagttt
     6121 ttttcctgct tttttgtttt tttcgatcaa gagtacgcgt gcgccttgtt cagctgcact
     6181 gatcgctgcc atcatcccgc ttgttccagc gccgactacg atcacatcat acagtttttc
     6241 cattccctca cctcaaggaa agtgtagcat atctgaagaa agaaaacaga aaaaaatgtt
     6301 ttgagccaaa agagaaaatg agctaaaatg agggaagata agcaaaggag cgtggaacga
     6361 tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa gctacatcaa aaggatcaag
     6421 ggcaagaaga atttttacaa gcaatcgatg aattcatgcc cacggttatg tcttttttgg
     6481 acactcatcc cgaatatatc gaaaagaata tcttagaact tttaacggaa ccagaaagag
     6541 ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa ctggcgagta aatagagggt
     6601 accgtatcca atacaactca gctatcggcc cttataaagg tggattgcgc ttccatccta
     6661 gtgtcaatct aagtatcttg aaatttttgg cttttgaaca gattttcaag aatagtttaa
     6721 ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt cgatcctaaa ggaaaatctg
     6781 ataatgagat catgcgtttt tgtcaaagtt tcatgctgga attgtcaaaa catatcggcc
     6841 catcgattga tgttcctgcg ggagatatcg gtgtaggagc tagagaaatc ggctatttgt
     6901 tcggcgaata taaacgattg aaaaaatatg atactggtgt gttgacaggt aaacctttgg
     6961 atttttgggg aagtaagata cgtacggaag ctactggtta tggattagtg tattatgtca
     7021 aacatctatt gaacgaagaa aaagattcat ttaatcaaaa aacagttttt gtttccggaa
     7081 gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga gctaggcggg aaagttgtta
     7141 catgttcaga ttctagcggg tacatctatg atccagaagg aatagatgtg aaactattga
     7201 aagaagtcaa agaaatcaat agacaacgtt tgacggaata cgcaaaccaa cgtccttctg
     7261 ctatttatca tgctggagaa tctgtttgga cattgaaaga aaaagcggat atcgctttgc
     7321 catgtgctac tcaaaatgaa atagacgaaa gcttggccga aatcttagta gaaaatggga
     7381 tcaaaatcgt agcagaaggc gctaatatgc catgtacagt aaaagctgtt tctgttcttc
     7441 atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa tgctggagga gtagcagtat
     7501 ctgctttaga aatgagtcag aacgtccagc gattgacttg ggaaagagag caagtggatg
     7561 agcagctgga tcaaatcatg gaaacgattt accatacgtg tcgccaaaca gcagccgagt
     7621 acggcgacga aaaaaatctg cttcttggag caaatgttgc tggatttgaa aaagttgcca
     7681 aagcaatggc agcagaaggt ttagtttgaa aaatgaaact ttcttggaaa tattgtcagc
     7741 attttgttta tttgcttgaa aaataataaa aaaaaacgta aagtattacc tgtagagtaa
     7801 acctataagg aggagaacaa atggcacaca ttcattttga ctattcaaaa gtagcaccgt
     7861 ttgtcaacga acaagagtta gggtacatgc aaagccaagt aacagcagcc cacaacgaat
     7921 tacgggaagg tactggcgca ggaagcgact tccgcggctg gatcgattta ccaacgaact
     7981 atgacaaaga agaatttgca cgtatcaaag aagcagctaa aaaaatccaa tctgattctg
     8041 aagtattagt tgttatcggt atcggtggtt cttatttagg cgctcgtgca gcgatcgact
     8101 tcttgaatca cacattcttc aatttattag atagcaacac aagaaaagca ccacaaatct
     8161 tctttgccgg aaattcaatc agctcaacat atattgctga cttgatcgaa gtaatcggtg
     8221 atcgcgactt ttcagtaaac gttatttcaa aatctggaac aactactgaa ccagcgattg
     8281 cgttccgtgt attcaaagag cttcttgtta agaaatatgg acaagaagaa gcaaacaaac
     8341 gtatctacgc tacaacagat aaagcaaaag gtgcagttaa agtagaagca gatgcagaag
     8401 gttgggaaac tttcgtgatt cctgatgaca tcggcggacg tttctctgta ttaactgctg
     8461 ttggtttgtt accaatcgct gttagtggtg cagatatcga tgcattgatg caaggtgccg
     8521 ctgatgcaag caaagcatac tcaagcgaca aactagaaga aaacgaagct taccaatacg
     8581 cagcaatgcg caacattctt taccgtaaag gcaaagtaac tgagttgttg atcaactatg
     8641 aaccaggaat gcaatacttc tcagaatggt ggaaacaatt gtatggtgaa tctgaaggaa
     8701 aagaccaaaa aggcatctat ccttcaagcg caaacttctc aactgatttg cactctttag
     8761 gacaattcat ccaagaagga cgtcgcaata tttttgaaac agttgtgaag gttgaaaaac
     8821 ctcgtaaatc aatcacaatt cctgaacaag cagaagattt agacggtcta ggctacttgc
     8881 aaggaaaaga agtggacttc gtaaatacaa aagcatttga aggaacattg cttgctcata
     8941 cagacggtga cgtgcctaac ttgctagtca aaattccaga aatggatgct tatacattgg
     9001 gttatacaat gtacttcttt gaaattgctg taggtatttc aggttacttg aatggaatca
     9061 acccattcga ccaaccaggt gtagaagctt acaagaaaaa catgttcgca cttctaggca
     9121 aaccaggctt tgaagatctt gctaaagaat tgaacgaacg cctgtaagat aagggttttt
     9181 cgctagattt aaataatcag tgatagaaac atgttcgctt taaaatgaaa actggtaccc
     9241 atttaggtac tcaaacatac tgcatcgttt attcagaata aggggctgtg acaagacgtt
     9301 tgtcacagtc ccttgtttgt atagaaatcg attgattgcc ttgctcttta gtttgtttta
     9361 ggactttaag aacagtgagg ctgacttcga aggttaattc tgtttttttg ttttctagaa
     9421 tcagtaagca aaaaagcact cacttcgagt gcttttttgc gatatattct tagcttaaga
     9481 taggcctaat ttttctttta cagatgaggg taccttatcg ctggtaatta cttttttctc
     9541 tatgatccgc ttttcgcttg ctttcaactg caagatcgtt ccttcggggt aagcagaacc
     9601 attggcagag tcaccagaag taatgacatc gaaatctaac tgtctttttt caccgttttc
     9661 agcataagca tctacgttgt atttaaaacc tcttccaatt acttccccat tatctgcttt
     9721 gatatcagtt tctgcaggca ttggagcttt gactaccgca taataatctt tacctacata
     9781 agtagactga tagtagtccc aacctttcca tcctataaaa gcaatcaata tgataacgat
     9841 caaccctaaa atttttttca tgaaagatct ccttttttat ttttatta
//
LOCUS       DACCVZ010000096         9874 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.099, whole genome shotgun sequence.
ACCESSION   DACCVZ010000096 DACCVZ010000000
VERSION     DACCVZ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9874
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.099"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(22..267)
                     /locus_tag="IVW63_002436"
     CDS             complement(22..267)
                     /locus_tag="IVW63_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860679.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(382..960)
                     /locus_tag="IVW63_002437"
     CDS             complement(382..960)
                     /locus_tag="IVW63_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP7860680.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1037..1567)
                     /locus_tag="IVW63_002438"
     CDS             complement(1037..1567)
                     /locus_tag="IVW63_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAP7860681.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1571..2431)
                     /gene="rlmB"
                     /locus_tag="IVW63_002439"
     CDS             complement(1571..2431)
                     /gene="rlmB"
                     /locus_tag="IVW63_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAP7860682.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2424..2819)
                     /locus_tag="IVW63_002440"
     CDS             complement(2424..2819)
                     /locus_tag="IVW63_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAP7860683.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2816..4228)
                     /locus_tag="IVW63_002441"
     CDS             complement(2816..4228)
                     /locus_tag="IVW63_002441"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAP7860684.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4225..4761)
                     /gene="cysE"
                     /locus_tag="IVW63_002442"
     CDS             complement(4225..4761)
                     /gene="cysE"
                     /locus_tag="IVW63_002442"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAP7860685.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            complement(5083..6543)
                     /locus_tag="IVW63_002443"
     CDS             complement(5083..6543)
                     /locus_tag="IVW63_002443"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAP7860686.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6713..7870)
                     /locus_tag="IVW63_002444"
     CDS             complement(6713..7870)
                     /locus_tag="IVW63_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAP7860687.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7904..9274)
                     /gene="radA"
                     /locus_tag="IVW63_002445"
     CDS             complement(7904..9274)
                     /gene="radA"
                     /locus_tag="IVW63_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAP7860688.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9337..9864)
                     /locus_tag="IVW63_002446"
     CDS             complement(9337..9864)
                     /locus_tag="IVW63_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAP7860689.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         2509 a         2214 c         1784 g         3367 t
ORIGIN      
        1 aatctcaggc tcgtttgctt tttaaactgc ttcagttaaa aattcgatct caactgtccg
       61 agtaagtaca tctgaatagc tgtaagatac tcgttcaaaa gaattttctt caggatccaa
      121 atcaacaacg aatactgaag gataggtttc tgttaaaacg ccgcggcgtt ctgtttgacg
      181 ctttcttcct gtctgagcaa ccaacatgat tgggctgccg atacgacctt ctaaatcttt
      241 cttgattgaa gctaaagttg ttggcataca gttcacctct actatcaact ataccacata
      301 tttttaaaat tttcaagttt accataaaaa aaaaagaaat gcaataaaaa taaataagaa
      361 gctcattaag atttttctaa attattcctc attataaaat ttcaagtgtt tttttatttt
      421 gagttttact ctcccgtaag cgctcattac ttgcttgtga tccattgcta aacattcagc
      481 catgtctaca aaatcaacgc cttgcatata ataatgaaaa attttagctt ctatttttga
      541 aaactggatt tcgcaatttt cgattgcttc ttttaataaa agatgctgaa tcgctaaagg
      601 ttcttgcaat gtgatctctg ctaaaaagtc tggtccttct gtctctattt tttggtcgat
      661 tgagacttca tctttttgat cacgacgctt cagcgcgttc tgcttcctca acagagaata
      721 gatttgattg cttataatgc ttttataata acttccaaag ctaacacctt tgcttttttc
      781 gtaagttctc aatgcctgat ataaagcgat ccttgcttct tgttcccaat cctcagaaac
      841 ataatttctt aaataatagg tgtttttcaa acgtagtaaa agtggaaaat atttttgata
      901 cagggcagca aatgcttctt cgtcaccatt acgtgcagcg cgcaataact cctcagacat
      961 aaaataattc ctccataaat tcgtttatgg aggaatctta tcatcaatga ttcatcgaac
     1021 tgattagaac gatatgttat ttattttttc tcattaaatc gtccaatttt tgggacaatt
     1081 tttttaactg ctcttcattc catggagaat tacgtcggaa atcaataaaa tgcatatctt
     1141 tattttcttg ggctattgtt ttttccgttt tttttatcgt cttatataat tcataagcag
     1201 aagttcgtaa tgctccttgg gaaaagatca tccactgttc tgctaaatcg cttgtcgcca
     1261 ctgtcacttg tgtcaaacgg tcattcagct gaccagcgat tctctcgata taactgtcag
     1321 ccgtttcgtc ttctttcgta aaaacaacat ccaactggta tttcttataa ttttgttgga
     1381 tgcccggaac tagttgggca tcgaagacaa cgatgacttc cattccttca tatttcgcat
     1441 aatttgataa acgatgtaaa agagcttctc ttgcatccgc cattttgtcc tgctttttaa
     1501 gctggacaag ttccggccac gaaccaatca tgttgtagcc gtctacaatc aacagctgtt
     1561 ttttcatggt ctactccccc tgacgttggg aaaaagcctg atacataagc aaaccagcag
     1621 caacactggc atttaagctc tggacgtgcc cggtcatcgg gatcgtcagc aattcatcca
     1681 tttctttttt caatcctgga ctcattcctt tgccttcatt accaatgact aaagcaattg
     1741 atcctttggc attccatttt tggaagtttg tgccggtcat atctgtgcca aatacccaaa
     1801 atcctgtttc tttgagctgt tgcacagctt gtaccaaatt cgtcacgcgt gcaacaggga
     1861 catgttcgac tgccccagtg gaagtctttg ttacgatagg tgtgattcca actgctcggt
     1921 gttttggtat gatcacacca tcgacgccac ttgcgtctgc tgtccgtaaa atcgacccaa
     1981 aattgtgtgg atcttcgatg ctatccaaaa tcaaaaagaa ggggtcttct tttttctctt
     2041 ttgttcgttc aatcagttgg tcaagggata aatattcata aggtgtaatc gcaagaacga
     2101 ctccttgatg cacgccgtga tcgctcaaag tttctaattt ttgtttagga acccatttga
     2161 ctggcacagc ttgttcacgt gcgatttctt tcagttcttc tactttttct cctcgtgaat
     2221 cttcttgaag aaagagttta ttccctcgcc cttgttgtag cgcttctact gcggcatggt
     2281 gcccaaagac gaaattatct tctaatgctt cttcattttg atcagaaact gactgatttc
     2341 gtccagtttg ctttttattt gaatatctat tttgtttttt gtcttcaaat ccacgtttcg
     2401 attgatgttt gtttgttctt tctttaccca tttttttcac caactttctg aatacaccag
     2461 cggatcaatt cttccatccg ctcggtttgt tttgtcaaat gcagatagcc catgagcgct
     2521 tcgaaccctg ttgcgacccg atacgtcgta acatcagcat tttttgcgct cgtatggctt
     2581 ttagcatttc ttcctctgcg ataataaagt tcttcttctt ctgtcaaaag atgttcttcc
     2641 agcatttgct gaatcaaaaa ggcttgtgca ttcgcagaaa cataattcgt tgccgcacga
     2701 tgcagcttat tgggttttgt ttctccttga tcaatcaggt ggtcacgaac atagatttcg
     2761 taaatcgcat ctccaacata agccaaggct aaaccgttca attgtgtgta atctctcatg
     2821 cttctcttct ccatcgggtt ccttgcggtg tatcttctaa taagatccct ttttctttca
     2881 acaaatcacg aatttcgtcg cttcggacaa aatcacgatt gcttcttgct tgatttcgtt
     2941 cttcgatcaa ttgttcaatc tcttcatcta ataactcttc tgctgtaaat aaaataccga
     3001 agatcgaaag ccattgcgag aataaagctt ctccttgtgc caagacagcg gcagaaactt
     3061 tcggctggtc tagataagtg ttcagccact tagcaagctc atagaccact gtgatcccat
     3121 ttgctgcatt aaaatcatcg tccatttctt cgatgaatcg ctgttctaaa ttttctaaca
     3181 aagcgatttt atccgcatca tctgccaaat tctctgaggc agtttcttgg cggaatttca
     3241 aattgtcaaa cgtattcttc agtcgttgta aattggtggc tgcttctttc atcgtcgttt
     3301 cactgtagcg gatcggacga cggtattgtg tggtcgccat gaagaaacgc aagacttgtg
     3361 gatcaacgtt tttgatcatt tcatgtacag tgatgaaatt ccctagagat ttactcattt
     3421 tttcatcgtc ttcgccaatc gttacatagc cattgtgcat ccagtaatta gcgaattttt
     3481 tccctgtttt cgcttcactt tgtgcgattt cattttcatg atgaggaaat tctaaatctt
     3541 gcccgccacc atggatatcg atcgtttctc ctaaatgttt tgttgccata acggaacatt
     3601 caatatgcca accgggacgt cctttgcccc atggtgaatc ccaagaaatc tcgccaggtt
     3661 ttgcttgttt ccataaagcg aaatctaatg ggtcttcttt ttgctgctgt tcttcccctg
     3721 tacgctgact tgctccgact tccagttcat cgatggattg gtcacttaat ttcccataat
     3781 tttcaaattt acgggtacgg taatacacat cacctgaaga ttcataagca tagccttttt
     3841 caaccaacac ttgaataaat gctaaaatat ctggcatatg atccatgact cttggatgca
     3901 gtgtagcagg ctcgacattc aacgctttcg tatcttcttc aaatgctcgg atgaaacgat
     3961 cagcaacttc tggtgctgta atacctaatt cgtttgctgt acggatgatt ttatcgtcta
     4021 catccgtgaa attcgatacg aaatcgactt tatagcctcg atattcaaaa tagcgtcgaa
     4081 ttgtatcgaa agcaatggtg ctacgagcat ttccgatatg gatataatta tacacagtcg
     4141 gtccgcagac atacataccg acatgtccct tttgtatagg gatgaattct tctttttttc
     4201 tggtcaatgt attgtagatt tttatcattc tgatctcctc actttttctc ctttgattcg
     4261 aacgactttt gctggtactc ctaccgctgt agcgtcgtct ggaacatctt tcaacacaac
     4321 ggcacctgca ccgattttgg cgttttttcc gatcgttacc ggtcctaata tctgcgcatt
     4381 cgcagagagc atggctcctt gtttaacagt tgggtgtctt ttacccgttt cttttcctgt
     4441 gccgcctaat gttacgccat ggaataaaat cacatcgtcc tcgatttctg cggtttcgcc
     4501 aatgacgatt cccattccat ggtcgatgaa cacgccagtt ccaatcgttg ctcctggatg
     4561 gatctcaaca ccagttagga aacgccagaa ttgagcattg atcttcgcca ataaaaagag
     4621 ccggtgctga tataaaaaat gagagaaacg atgccaaaac aaggcatgaa aaccagggta
     4681 tgtcaaaacg atctcagctg tcgaacgtgc agccggatcg tttctctttg ctgcatcaat
     4741 cgctcgggta aaccaactca tgactttcca ctcctttcgt aagaatttta tgtaggaaat
     4801 catcttctta taaagaaaag aagcgccttt taaataagtt tccttatcaa aagacgcttt
     4861 ccgcgtggtt ccacttttct tcataatcaa tgattatctc tgacagctaa cgcctgttat
     4921 acgttcttgg ctactttgtt tcctataaaa cagtttttcc tgttttctgt gtttcgccaa
     4981 gaccactccc agaggcattt cggcaaccat tcattgatac cttgcaccac ccggtatctc
     5041 tcttgtaatg atcagctgct tacttttttc tgttcatcgt gtttagttca gtacttgatt
     5101 taaatgtgct aatgattttt cacgaccaag caattcgatc gtttcaggca attctggacc
     5161 atgcatttgt cctgatacag ctacacggat tggcatgaaa agattttttc cttttacgcc
     5221 agtttctttt tgaacagctt tgatggcagc tttgacagtt ggagcatcta ctacttccat
     5281 ttgttctagc tgtgctttga atgcgtggag aacagtagga actgtttcac cagcaagtac
     5341 ttcttttgct gcttcattca atacaggatg ttcattgaaa aatagcgtag acagatcaac
     5401 gatttctgca gcatagctca tttgaggttg atacaggcta acgatcttct tcacccattc
     5461 gattgtcttt tcatctgggt tttctgctac acgtccatca gcgattagat aaggcagaca
     5521 catgtcagta aatgcatcta gatccattgc tttgatgtaa tggttgttta cccattgcag
     5581 ttttttcgca tcgaaagctg cgggtgattt acttaggcgt tttggatcga acattttgat
     5641 caattcttgg tgttcgaaga tttcgtcttc gcccacaggt gaccagccca ataatgcaat
     5701 aaagttgaac attgcatctg gtagatagcc taattcgcga tattgttcga taaattgcaa
     5761 gattgattcg tcacgtttgc ttagtttttt acctgtttca ctgttgatga tcaatgtcat
     5821 atgtccgaag gttggtggtg tccagccaaa tgcttcatag atcatcagtt gttttggtgt
     5881 attggcaata tggtcatctc cacgtaaaac gtgagtgatt ttcatcaaat gatcatcgac
     5941 cgcaacagca aaattataag ttggcatacc atcgcgtttt tgtatgacaa agtcgccacc
     6001 gatattatcg gattcgaacg aaatagcgcc tttcaccata tctgtaaatg cgtattctgt
     6061 attgcgaggc acacggaaac gtacaacaga ttctagacct tgtgcttctt tttctgcttg
     6121 ttcttcaggt gtcaagttcg cacatgttcc tgcgtaatga ggcatttctc ctcttgcgcg
     6181 ttgtgcttcc cgttctgctt ctaattcttc ttctgtgcaa tagcatttgt atgctcgatt
     6241 gctagcaagc agctgatcaa tcagcggttg atagatttct ttacgttcag attgacggta
     6301 agggccgtat tctccaggat tttcaggaga ttcatcccaa ttcattccca accaagcaag
     6361 gttttccaac tggctttttt cgccatcttc gatattacgt ttttggtcag tatcctcaat
     6421 acgaataata aagtctccat cattgtggcg ggcaaacaaa taattgaata atgcagttct
     6481 tgcatttcca atatgcaggt gcccagttgg acttggtgca tagcgtacgc gtactttcgt
     6541 cattttcttc ctcttctttc aaactagact ttgactaaca gcaaaaattc cgtcagttac
     6601 ggcttctcaa atatcattta tttaaagcca ctcagcacaa attttacctt ttctaaggta
     6661 aatagtaaag ccaactggtt gaatttcctt accagttggc tgaatttctt ttttattttg
     6721 attgtttagt ctttttctct gtctcttttt tattgtcgat tcctcgtcct gcatgtgcag
     6781 gtttagcaaa gatcatgcgt ccagcagctg tttgaagggc acttgttaca acgacttcga
     6841 tacgttcatt catgtaatgc tgtccatctt ctacgacaac catcgtgccg tcatcaaggt
     6901 aggctactcc ttgttggcgt tctgtcccgg cttttactac tagaacattc atcgtttcac
     6961 cagggatgac gactggtttt acggcatttg ccaacgcatt gatattaaga acaggtacat
     7021 tttggaattc agagacttta ttcaagttat agtcattggt tacaatgaca ccatctaaaa
     7081 gcttagccaa tttgatcaat ttgctgtcta cttcactgat atcttcaaag tctccatcgt
     7141 acatttcgac agatataccc tcttcttttt gcaaggcatt taggatatct aatccgcgac
     7201 gaccacgcac acgtttcaaa ctatcccctg agtccgcgat gtattgtagt tcgtaaagaa
     7261 caaaattagg gatcatcaag gttccttcta agaatccagt ctttgtaata tcataaatcc
     7321 gaccgtcaat gatcacgctt gtatccaaga ttttatattt atggaaattt tctcctgatt
     7381 ttcgttctaa cagttgactc tcaacttgac tagctgtttc ttgctcgatt tttttgcttc
     7441 gtgaaccaaa aactttcttc cattcttcga ttcgtgtcgt tcccattctc aatcccagat
     7501 agcctaagat gatcatcagt aaaatcggca atacactatt gacgaatgga atttccatat
     7561 tgtaaagagg ggtcgagatc acaacaccta aagtcaatcc gatgatcgca ccgatcgcac
     7621 cgaagagaag ataagtcaag ctgacctcac ttagtttttg ttctacttgt ttgataatag
     7681 ctgagatatg tttggccaac agcaaagata ataaaaagaa aataagtgcg cctaacaggc
     7741 tgttggtaaa tgtattattc agccatccgt ttgactgttg accgattgcc tgccaagctg
     7801 agggtaaaaa tgaaataccc aagcttgcgc cgacaatgat catcagcaaa gtaatgacac
     7861 gtttttgcat cgtttttcct ccgtttcgac aatcatttat tagttagcgg aacacacgct
     7921 tcaacgtttc agccaaagtt gctactccaa ctatctcgat tccttttggc gcttcccagt
     7981 tacctaagtt gtttttaggt aggtatactt ttgtgaagcc gagtttttgg acttctttga
     8041 ctcgttgttc aatatgactg acacgtctga tttctccagt cagtccaatt tcaccgatga
     8101 aacattccgt tggctgtgtt cctttttctt tatagcttga agcaatactg acagcgatag
     8161 ctaaatcaat cgctggttca tttaatttta ccccacctgc agcttttaag taagcatctt
     8221 gattctgaag aagcaaccca gctctttttt ccagcactgc catgatcaga gatacccgat
     8281 tgaaatcaag acctgttgtt gttcgtttgg catttccgaa catagtaggt gtgactaatg
     8341 cttggatctc taccaaaatt ggacgtgtcc cttccattgc cacaacgata gcagagccag
     8401 ttgcaccgtc taggcgttct tctaagaaaa tctgtgaagg attagcgact tcttccaatc
     8461 catgctcatg catttcaaaa atcccaatct cattcgttga gccaaatcgg ttttttactg
     8521 ctcgcaaaat ccgaaaacta tgatgttgtt caccttcaaa atataacacc gtatccacca
     8581 tatgttctaa cattcttggg ccggcgatcg agccttcttt ggtaacatga ccgacgataa
     8641 aaatggctat cccatttgtt ttagcgattt tgagtagttc tgcagtggtt tctcttactt
     8701 ggctgacact tcctgccaca cttgtgatgt ctggctgcgt catcgtttgg atggaatcaa
     8761 tgataacata atcaggggag atatgttcga tggcacgact gatttcgttc atatctgttt
     8821 cagcgtatag ataaaattct gtgttgatac ttccgaggcg ttccgcgcgt aattttatct
     8881 gctctgcgct ttcttcgccg gatacatata agacttttcc gcctatggct gctaattgct
     8941 gagaaacttg taacagcaaa gtggatttcc cgatacctgg atcgccacca atcaagacca
     9001 tagaccctgg caccacacct ccgcctaaca cacggttcag ttcttctaat tttgttttga
     9061 tccgaggttc ttttttaggg acgacgtctg cgatttttgt tggttttgct ttttctcctg
     9121 tcaaacttgt ccgagttctg cggtccgttg tatcttgttc gatttcttcg accatcgtat
     9181 tccattttcc gcaatttggg cagcgtccca agaacttagg cgacacatac ccgcaatttt
     9241 ggcaaacaaa ttgtactttt gatttttttg ccattgtacc gcctcctttt atcctaatca
     9301 tgagacatta aatcaagctt aagtatcttt aacgttttat ttactggaag aaccaaatcc
     9361 gccttgacgt tgagcagtcg tttgatcttg atctgctttt aaaaacggca aaaagatccc
     9421 ttggccgata cgctcgcctt ttttgatcac tacatccttg aaaccaaagt tggtgaattg
     9481 gaacatgata tggccttcat ttgcctcatt attgtaataa tcactgtcaa tcacacctac
     9541 tccgtttgtc aacactaaaa accgcttcaa cggattgctt gaacggttag caagctgcaa
     9601 aaattcatct tctcccatgt aagctttgat tccagtaggc acgagggttg gtttcaattg
     9661 tttttcattt tctgatacat cttttttcaa tccatctgcg actgtttcca accccttttt
     9721 ccagcctgct ttccagatac ttggaatcac gacctcttct gctgcttcaa aatcatagcc
     9781 agcagcatga tgtgtagcgc gctgcggtag attgatattt tgatctttat atttagaaat
     9841 aacttcaaat cctctttttc tcaccggttt tcct
//
LOCUS       DACCVZ010000097         9667 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.100, whole genome shotgun sequence.
ACCESSION   DACCVZ010000097 DACCVZ010000000
VERSION     DACCVZ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.100"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..650)
                     /locus_tag="IVW63_002447"
     CDS             complement(<1..650)
                     /locus_tag="IVW63_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP7860690.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIG"
     gene            975..1391
                     /locus_tag="IVW63_002448"
     CDS             975..1391
                     /locus_tag="IVW63_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP7860691.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            1388..1858
                     /locus_tag="IVW63_002449"
     CDS             1388..1858
                     /locus_tag="IVW63_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7860692.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            1872..2645
                     /locus_tag="IVW63_002450"
     CDS             1872..2645
                     /locus_tag="IVW63_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7860693.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAAAPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            2659..3471
                     /locus_tag="IVW63_002451"
     CDS             2659..3471
                     /locus_tag="IVW63_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP7860694.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            3525..4490
                     /locus_tag="IVW63_002452"
     CDS             3525..4490
                     /locus_tag="IVW63_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP7860695.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            4606..7329
                     /locus_tag="IVW63_002453"
     CDS             4606..7329
                     /locus_tag="IVW63_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7860696.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESKILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGEAIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            7342..7974
                     /locus_tag="IVW63_002454"
     CDS             7342..7974
                     /locus_tag="IVW63_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP7860697.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKDLRKEVKPLLDFLKKRDIP
                     LALASSSPVVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTVALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            8873..>9667
                     /locus_tag="IVW63_002455"
     CDS             8873..>9667
                     /locus_tag="IVW63_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7860698.1"
                     /translation="MKNLQLKFIVDPSIVRWFRIINQFERNQLATKGELAKSNHVSER
                     TIQTDVNKMKDYFSESVQFVSTKSGYSFQKERPVLFLKQKEQLLENEILFELLGNVFY
                     GELEDMTELIDRFHLSEATFRRYLKQIQPVLEEYGLELSLYPLDLKGEEANIRKFFKD
                     FYYEGEMTPHTLVPPRDLHELVQATFYDKFEYFSIGTGTSPAEFYYSLYIAIERVRQG
                     KTIAIPQGLIERVIASENFRLMYSLKEAIQTNYQVALSEEEFCWLYL"
BASE COUNT         3261 a         1477 c         1884 g         3045 t
ORIGIN      
        1 ccaatcatat ggaagccacc gattaggtat tttatgggtt tagtcggaaa tgtttcaaga
       61 gcaatttcca tcatatcgat aatgccatga tgactacagc cagtaaagac aatcagaccg
      121 tcttcttgct caattacgac caataattca tctgaaaaat catcataaac aaatttatca
      181 tccatctttt tgtataaatt cttggtggtc gagtttgctt tgcctagggg gatgatatgg
      241 aagctcggag caagttctgt tttcgttttt attgtatgta aattctcatg cattttaagg
      301 atttcatttt taggaatacc aacatacaga aacgtggtta aaatctttaa ataatggggt
      361 aaagttacac cttcagctgt ataaataggg gcgtttcctg attttaaata tcttaacccg
      421 ccggtgtggt cagaatgacc gtgtgaaata atcactgcct ccagatcatt caaagtttcc
      481 cccattttag tcgcattata gactaatttt ttattagcgc cagcatcgaa gagatatttc
      541 ttccctgagt agttaattaa gagagataac ccatgtccac ttttaaagtt caaatttatt
      601 cttgagtttt caaataaaac cttgatttcc actataacat ctcctttcac atgaacgtgt
      661 attcatatat tgtagcacat taagttctat tttttgttgt aattaccgaa aaaaatatta
      721 atggacgctt tttacgcttt atttcgtatg tggaagaaaa tttcttagga tgtggcgggg
      781 gattggggca aagctaaatt ccaattacag tgatcattta attagacacc tttaaatacc
      841 cacactttca tcaacactat aatttaggga aagaaaagtg ttggcatgat atagaaaaac
      901 ctttaattaa cagcgtttcc taaaattggc acgcatcttg cttatagaaa agcgtaagga
      961 taggaggaat gaaaatggca actataattc ttgccagcca tggggaattt gctcaaggat
     1021 taaagcaaac agctacaatg attattggag atagtgtacc aattcatgcc ttgtcagcat
     1081 ttagagatga agatgaatct attttggtac aaataaaaaa acttttagcc acaatagata
     1141 tagaagaaac ctacatttta actgatattc taggtggtag tgtgaataat gatatgctca
     1201 ctattattaa agagtatgag ggattgcaat taattactgg aatgaactta cctttagtta
     1261 tttctattgc aacctataat ggaaaaattg gggaaagtga gctagaaaag cttattaaag
     1321 agagtcaaca atcagtgatt gattgtagaa aattattagt agaacaactt actggaggag
     1381 atgacctatg attaagttag tacgtattga ccatcgtttg ttgcacggac aggtagtatt
     1441 ttcttggagt aaatcattaa atatcaatcg tattattatt gccaataaag aggcagcgaa
     1501 tgatgaattc aaaaaaatgt ctttgaattt atctaaaccg actggcatta aattaacaat
     1561 tttttcagtt gaacagttac tagaaaaaat gcctaaaatc gaaacactta acgaaaatat
     1621 catgcttatt tttggtaata caaaagaaat tcgtcaattt tgtgaagcct atcctaaagt
     1681 acaagaaatc aactatggag ggataatcaa aaaagaaggt tccaagcaat ttagtaatgc
     1741 cattttcttg aatgaatctg agcaagaaga tgccaaaaaa ttaaaagctc ttggcattaa
     1801 acaatttatt caacaggtac caacttctaa aaaagaagat ttgaatacaa tgttataaag
     1861 gaggaatgaa aatgctcgtt cagtcaattg gtttagggtt aatcggtgtt ttttgtattt
     1921 tagactcaag gcttttagga agaatgaatt ttgaacgacc gttgattgtc agtacgcttg
     1981 ttggtttggt acttggagac atggaaaaag gattaattgt tggagcctct ttggaattga
     2041 tgtccttagg attagtaaat atcggagctg ctgcaccacc tgatatgaat atggcatcaa
     2101 ttattgctac agcctttgcc attttatcaa atgcgaatgc agaagcagca ttaacgattg
     2161 ccattccaat ttcagtgtta ggtcaaatac taggtatctt aatgcggacg attttgtcaa
     2221 atttgactca cgttgcggat cgctttatcg aacaagggaa atttagccaa gcaaggagaa
     2281 ttcatatact ttatggctcg ggattatatg ctctcatgta ttttattcct atttttctag
     2341 caatttattt tggaacgaat cttgtttctc agattgttga tgcgattcct gagtggctaa
     2401 caaatggctt aacggttgca agtaaaattt taccagcata tgggtttgcg ttgttattac
     2461 aaacgatgtt aacgaaaaaa atggtgccat ttttattact tggattttta attactgctt
     2521 attctggatt gggaatcatt ggtattgcag ccttcgcatg tattgttgcg tttgtcatgg
     2581 ttcaagttca aggtaaaaac tcaaatggta accaaaatga gccagatcca ttagatgact
     2641 tataaggagg tagattaagt gaaagagaaa gatcaaaatg catggaaata tcggcagttc
     2701 ttatggcgtt catgggcaat tcaagcctca tggaactatg aacgacaaat gaacatgggt
     2761 tttatgtacg gaattgcacc aattctagat aacatttaca agaatccaga agatgaagca
     2821 atgaagaaag aagcttacga gcggcatatg atgtactaca actgtacccc tcaaacaagt
     2881 gcatttgtgt tagggttaac tgcttctatg gaggagcaat actacgaaga ccaagaaaac
     2941 tttaatccgg aatcaatcag tgcagtgaag acttctctga tgggaccgct atctggtgtt
     3001 ggtgattctt tctttcaagg aacgattcgg gtattagcct ttggactagg aattaattta
     3061 gcccaacaag gtagtatttt aggtccaatt ctagcaatgt taatttcctt tgtaccttcc
     3121 tttttagtta cttactatgg tgggaaaatt ggctataaca tggggaataa atacttgtct
     3181 aaactgtatc aagaaggttt gatggataaa gtaatgtatg tttgctccat tgtggggttg
     3241 atggtcattg gttcgatgat tgccagcatg atcgggatta caacaccaat tcaaatgggt
     3301 aaagcttttg tcttacaaga tgtattagat agtattatgc cacaattttt accattagga
     3361 ttaaccttct tcatgtactg gttattgcag aaaaaggtca aaacaggatg gatgttggca
     3421 atctgtttag tcggaggaat tatttttagt ttgttaggta tcttacaata agggaataac
     3481 caataaattt ggttgaataa tataaataag gaggaattca attgatgaat tcaaaagaaa
     3541 ttgttaaaga aatcgtagcg aaaaaagagg taaaatcaat cgtatttgtt ggctgtggcg
     3601 cttcaaaagc ggacctttat cctgcaaagt attttctaga ccaaaatgcg aagcagttac
     3661 ggattagtca ttacacagcc agcgaattta actatgcaac accagcatct gtagatgagt
     3721 caactgtcgt tatttcagct tctttaggag gtacgactcc agaaacagtt gaagctaacg
     3781 cagtagctaa agaaaaaggt gctacagtta ttagtctaac acgaagcatt gactcaccgt
     3841 taacaaaaga tgcagattat gtaatttatc atcgatttgc agagaactat gctgctaaat
     3901 tagaaaaaac aggctactgt ttagaattgg cagtagaact tttacatcaa gtagaaggtt
     3961 atgaccatta tgaagcaatg caagaaggat ttgctactat ctatgatctt gcccaaaaaa
     4021 gtgcagaatc agctcgtaaa gatgcgaaga aatttgctga acgctttaaa gatgaaaaag
     4081 ttatttatgt aatgagtagt ggtgctacac atgaagtagc atactcaaca tcaatttgct
     4141 tgatgatgga aatgcaatgg attaattctg gtaccttcca ttcaggagaa tttttccacg
     4201 gaccattcga aattgtggat aaagacgtac cgtttatatt attaatgaat gatggaaaaa
     4261 ctagaaatat agatgctcga gcattaactt tccttgaacg ctttgatacg aaaacagaag
     4321 ttgtagatgc cttggattat ggcttgtctt cacatattgc taaagaagtc ttagactact
     4381 ttaacccatt cgtgattact gcagtattta gagtttatgc agaagaattg tcagaagcaa
     4441 gagaacatcc attaactaag agacgttata tgtggaaact aacttattaa aaaatagatc
     4501 aaactaaata aggtggcttg agaaattaag ccaccttgtt ttcttcaatg tgattttata
     4561 catatggtaa aataactagt acatattgtg aaagcaggtg gcaagatgca gcgattaaat
     4621 gactatcttt atcaactaac attgcttttg aaatctacgc cttcagataa ttattcagct
     4681 cgcagtattt cgcaagcttt acagttgaat agaagtacaa tcagtagcta cttaaatgaa
     4741 ggtgttcgtg aagggctttt cataaaagta aaaagttacc cggttttatt tttacataga
     4801 acagctcttg aagaactaca tatcacactg aataactccg aaatagaatc aattgaaagc
     4861 ttgttaacaa tttctcaaaa acccgcatta gatcaagtaa ttggctctaa aggaagtttg
     4921 aaagaagcaa ttgatcaaat taaaacggca gtcttatatc ctggaaaagg gttgccttta
     4981 ttattgatcg gcgctagtgg atcagggaaa acctttctag cgaataaaat atatgaatat
     5041 gcagtagaag aaaaggtcat tcacacatcg gcacctttca tagattataa ttgtgcacaa
     5101 tatgtgagca atccagagtt actatcctct gctttatttg gctacacgaa aggagcattt
     5161 accggagcaa gccaggagca tactggtttg ctagaaaaag ccgatggagg agtattgttt
     5221 ttagatgaag tgcatcgctt atctgaagaa gggcaagaga aattatttac atttatggat
     5281 acgggtgaat tctctcctat gggggataat agtattcgga aaaaagccga tgttcgatta
     5341 gtctttgcaa caacagaaaa tatatatacg actttcttac caacttttct taggagattg
     5401 ccagttattg ttaatctacc tagatttcaa caacgtccgt cgtttgaacg tctgtcattg
     5461 attgatgaat tttttgtttc tgagagtaaa attttagcta aggaactatc tgtttctgat
     5521 gcattgattc atttcttaat gaatagtgat tttgaaggta acgtggggaa tattaaaaat
     5581 attatcaagt atgcttgcgg aaacgcatat atccaccaga agagtcagca aacaattcaa
     5641 gttaaattat tggatatgcc tttagagtac agttataaat tcaaggagca actaaataaa
     5701 cccagaaaga aaagagcaga tcgaatctac tatccagaag aaacacgaca agtgcaacta
     5761 gaaagaaaca atcagctttt tgttcaattt tttgaccaat tacttactgg attctctgaa
     5821 gtgattgaaa ataacaagga tattaaacta tttttagaag aaatggttac caaggtaaca
     5881 caagtaatgg atacgcttat ttttcaagag gattacgaaa aagagcagtc tttatacgcc
     5941 attctaaact atcatattcg tcaaagtatt gattttatgc gagaaagcta cgggtttgaa
     6001 caagatggta accgggtagt cgctttggcc aactatctat atgtcaagga taatcaagtg
     6061 atttttgaaa atagtcttca agaaaagaaa accaaagatc agcttaacga attttttgct
     6121 aatgttcttg aaacccctta ttggtatgca aaaaaaatct taagcctttt atctgagtgt
     6181 ttagatcaac ctgtgtatga agaggacatt ttctttatta cgctatattt ttatagtttg
     6241 aatgtcacga atgttaaaac aggtattaag agtattgtgc tagctcatgg ttattctaca
     6301 gctagtagta tggcgaatgt tgccaaccgt atgctgaata agaacgtttt tcaagcttat
     6361 gatatgcctt tagatattac attagagaaa attgaagcaa aattgattca attccttgga
     6421 gattatcgaa cagattcagg cttgatttta ttggtagata tgggttcact aaaccaacta
     6481 ggcggtttat tagtgaatca tctaaatgga ccactgttaa tcattgatca tatcaataca
     6541 ccgttattat tggaagtcgg ccaacaagta ttaaacaata aaagtatcac cgaaatagga
     6601 gcagaaattg aaacaagtct tactttcaaa aagcagttac tacttcccaa gaaaaagaaa
     6661 aagaaagcca tcattacttg ttgttataca gggattggta gtgcgaccca gattcaggag
     6721 attttaacga aatgcttgaa agatgcagtt agagaattag taattattcc gtatgattac
     6781 aaaaagctgt tagaaaacaa gaattttgag actccttttc aattatacga tgtcatcatg
     6841 attgtaggta cagaagatcc caaaattaat cagattccat atattggatt agatcgcctg
     6901 attaatgggg aagcaattgg cgaatttgtt cattacttgg aaaaagagct gactattgaa
     6961 gtgaacgatt tacaaaaaga attaattttc aatttttcaa ttagtaaaat tgtcgaaaat
     7021 ttaaccattt tggatccaga taaggtgcta tcttttgtac aaaaagcaat taaagaatta
     7081 tcgaagttat taaattttga tttttctaat aatcagctgt ttttgttgta ccttcactgt
     7141 agttgtatga ttgaacgaat tgtacgtaaa gaaagtgtgg atgagcaaga ggacattgaa
     7201 gaatatatgc aagcaaatgg agaaataatg gataaaattc atagcgcttt ttttgagatt
     7261 gaaagggaat acacaattga aataccagat ttagagttgc gattattgag cgatattgtt
     7321 caaggatagg agtgaattcg aatgacaatg ggagtaattt ttgatatgga tggggtactc
     7381 atagacagcg agacatttta ttttgagaga agaatgaact tctttcaaga actggagata
     7441 gatccaggat caaaccagat tgatgattat gtggggaaaa cagaagctgc aatatgggaa
     7501 acattagttc ctgaggacaa atcattaaga gaggaacttt atccgaaata tgtagattat
     7561 cgaaaaacgc atccaattga tttcgctaaa gatttacgaa aagaagtgaa accgttactt
     7621 gacttcctca agaagcggga tataccattg gcactggcat cttcttctcc agttgttgag
     7681 atagagagta tgctcattca atgtgaactt actgaatatt tttcctttgt tataagtggt
     7741 gagtcattaa aacaaagcaa accacatccc gaaatatatt taaaagcgaa acagcaatta
     7801 gactgtgact tctttattgc agtagaggat tcaacgattg gtattaaatc agcaaaggca
     7861 gcaaatatct atacggtggc actaaaacaa ccaatgcaaa tcgatcagag tgaagcagac
     7921 atacaaattg aaagtctaca agaactggaa caaattgttt tagaaaaagg ttagtgaatt
     7981 aatggaaata aggctatata tctgtgctag ctattttgac taaccaaaaa aacttgctat
     8041 aattcaggtg tagtaaaagg tgctggtaac accttttacg aaaatgcttc ggcagtgata
     8101 atgggattgg ctttttaagt tttttatttt gttcgcaatc cctaaggtca tgtgaatgat
     8161 cctagggatt gctagaatat tttgcaacat tctatctatt tcagaacgta accttcccca
     8221 gttcattggg attcattagc atacaaccaa catttcaaaa agaaattgca ctacaccatt
     8281 attagctatt ttgactaacc ccaaaaaact tgctataatt caggtgtagg taaaaggtgc
     8341 tggtatcacc ttttacgaaa ctgcttcggc agtggtaatg agtgtggctt aaaggactag
     8401 tcctttaagc tttttacttt gttcgcaatc tctaagatca agttaatgat cgataagatt
     8461 gctagaatat tttgcaacat tctatttcag aacgtaacct ttcccattcc actgtgattc
     8521 attggcaacc ctcctcacaa ccaacgtttc aaaagaaatt gtaaagttgt tggggtacca
     8581 cgaccgaaca atactacacc tgaatgatag taagttgtct cattaagtat agcatatcct
     8641 ctttttgggt aaatagaaat cggttacatt ttttatccaa gaccaagttt tttcatttgg
     8701 tcttatttgc tatacccaaa caattccgca gtatagtcga cggtattgat tttatcaggt
     8761 gagtaataga aacttgtttt ccttccccaa aacattacct ataaaggaga aaaaatggta
     8821 tcgtaattat ataggtatag gatgaaattt ttttctaaga ggagggttgt tgatgaaaaa
     8881 tttacagtta aaatttattg ttgatccatc gattgtacgc tggtttcgga ttatcaatca
     8941 atttgagcgc aatcaacttg ccacaaaagg agaattagca aagagtaatc atgtatctga
     9001 acgaaccatt caaacagatg tcaataaaat gaaggactac ttttctgaaa gtgttcaatt
     9061 tgtttcaacg aaaagtgggt attcttttca gaaggaaaga ccggttcttt ttctcaagca
     9121 gaaggagcaa ctactggaga acgaaatttt atttgagttg ttagggaatg tcttttatgg
     9181 cgaattggaa gatatgacgg agctaattga tcgttttcat ttatctgaag cgacttttcg
     9241 tcggtatttg aagcagattc aaccagtttt ggaagaatac ggcttagaat tgagtcttta
     9301 tcctcttgat ttaaaaggag aagaggcaaa tattcgcaag ttttttaaag acttctatta
     9361 tgaaggggag atgacgcccc atactcttgt tccaccaagg gatcttcatg aacttgtgca
     9421 agctacattc tatgataaat ttgagtattt ctcgattgga acagggactt ctcctgctga
     9481 attttattat agtttgtata ttgcgattga gcgtgtgaga caaggaaaaa cgatagccat
     9541 tcctcaaggt ctgattgagc gagtaattgc tagtgagaat tttcgcttaa tgtattcctt
     9601 gaaagaagcg attcaaacaa attatcaagt tgctttatca gaagaggagt tttgttggtt
     9661 gtattta
//
LOCUS       DACCVZ010000098         9614 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.101, whole genome shotgun sequence.
ACCESSION   DACCVZ010000098 DACCVZ010000000
VERSION     DACCVZ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.101"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..643)
                     /locus_tag="IVW63_002456"
     CDS             complement(<1..643)
                     /locus_tag="IVW63_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAP7860699.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTK"
     gene            complement(645..1409)
                     /locus_tag="IVW63_002457"
     CDS             complement(645..1409)
                     /locus_tag="IVW63_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HAP7860700.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(1417..2094)
                     /locus_tag="IVW63_002458"
     CDS             complement(1417..2094)
                     /locus_tag="IVW63_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HAP7860701.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(2131..3516)
                     /locus_tag="IVW63_002459"
     CDS             complement(2131..3516)
                     /locus_tag="IVW63_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAP7860702.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(3726..3810)
                     /gene="ffs"
                     /locus_tag="IVW63_002460"
     ncRNA           complement(3726..3810)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="IVW63_002460"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(3833..4348)
                     /gene="tadA"
                     /locus_tag="IVW63_002461"
     CDS             complement(3833..4348)
                     /gene="tadA"
                     /locus_tag="IVW63_002461"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAP7860703.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            4455..5312
                     /locus_tag="IVW63_002462"
     CDS             4455..5312
                     /locus_tag="IVW63_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAP7860704.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(5393..5728)
                     /locus_tag="IVW63_002463"
     CDS             complement(5393..5728)
                     /locus_tag="IVW63_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860705.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(5795..7165)
                     /locus_tag="IVW63_002464"
     CDS             complement(5795..7165)
                     /locus_tag="IVW63_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NOL1/NOP2/sun family putative RNA methylase"
                     /protein_id="HAP7860706.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(7243..7779)
                     /locus_tag="IVW63_002465"
     CDS             complement(7243..7779)
                     /locus_tag="IVW63_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7860707.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            8088..9569
                     /locus_tag="IVW63_002466"
     CDS             8088..9569
                     /locus_tag="IVW63_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP7860708.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         2912 a         1973 c         1506 g         3223 t
ORIGIN      
        1 tttttgtttg tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta
       61 ataatacaaa aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga
      121 ttggatcagt aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa
      181 ggataaaaaa gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca
      241 tgccgatttg aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga
      301 taaacaaaat actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa
      361 ttttcacttc ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga
      421 ggatggtttt gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg
      481 tctcttgatc taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata
      541 gtggtcgaaa gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga
      601 acaatccagc atattccatc cactgccatc tcgaattttt catattagaa gctccattca
      661 tccagtgatt gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt
      721 gtaaaacctg ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct
      781 gtttcatagt tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg
      841 gctttatcca taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct
      901 gtctctacaa aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata
      961 ttcttatctg ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta
     1021 actacttttt cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct
     1081 tcttcccatg taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca
     1141 tagacttttt tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg
     1201 tagactgtct ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt
     1261 tctggtgact tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat
     1321 tcttccacaa atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct
     1381 aaatcaatta aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt
     1441 aaatgctgtt tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga
     1501 ggtttttgct gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac
     1561 tggtcctttt ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg
     1621 agttgtcttt tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt
     1681 gcaatattcg taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg
     1741 attatccgct tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat
     1801 ataatcatat cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc
     1861 ttcacgataa tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc
     1921 taacagtgtc actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc
     1981 caaagcagct gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt
     2041 agcaatttct gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc
     2101 accacctatc ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta
     2161 atctcctacc acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc
     2221 aatcgttgga aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt
     2281 attcagatcg attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat
     2341 tccattatag accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata
     2401 gttacgtaaa aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc
     2461 acccaatgtg acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg
     2521 attgacccgc ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc
     2581 cgtctttcct cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa
     2641 gatatctaga ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg
     2701 cccacgttct agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc
     2761 ggtagggatg gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg
     2821 gacttcaccg acatactgcc cgtactttcc agcggctgct atttggacat cattgattac
     2881 gtgaccttct ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat
     2941 ttcttttgca atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc
     3001 cacttgtgaa cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc
     3061 ccagccattc ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt
     3121 cgtctggtgt ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt
     3181 atttttatcg aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt
     3241 caactcttct ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc
     3301 aacttcattc atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca
     3361 acgatccaca aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt
     3421 ttctcgttta cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg
     3481 cagatcattc gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct
     3541 ttatcatacc ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc
     3601 tgccttgaag caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag
     3661 gaacattcat ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg
     3721 tttcattata atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac
     3781 acgcttcaca agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt
     3841 cattcgttga ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt
     3901 cagtcaaaat catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt
     3961 taaaccgctc gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat
     4021 acgcgccgaa ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac
     4081 aaggctctaa ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac
     4141 aggcttcctt gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa
     4201 ggttatatcc tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt
     4261 catgaagcat ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt
     4321 ctactgcatc aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt
     4381 tactttagca tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac
     4441 aagaggtgaa caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa
     4501 aaaactctcc agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct
     4561 ggatcaaaca agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg
     4621 taatcaacga tcaaaaaaaa cacccatggt atcgctatct ttttaaagat gcttcttgtg
     4681 ttcaagaaaa aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa
     4741 aaaaagaatg gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt
     4801 atacagacac agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatgctactg
     4861 aaatcaacgg tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg
     4921 ttggttcttt ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa
     4981 tttttttaac agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg
     5041 tggctttaca ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca
     5101 tagaactgat caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag
     5161 gcaatgtcag ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa
     5221 tcgaaaaatt tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt
     5281 gctatctttt attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa
     5341 ttttgtcaca accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca
     5401 ttttttcaac aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat
     5461 caccataaac agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag
     5521 aatccaagtc actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa
     5581 atttgtcata gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca
     5641 ttacttttcc cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc
     5701 cgattgttac ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca
     5761 tagcatagac aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga
     5821 aaaagttctt tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata
     5881 ctagcaaaac ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt
     5941 gccattcctt ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg
     6001 ctaatgcata gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac
     6061 gtacgacttt taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt
     6121 tgaacactaa aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga
     6181 gtttttcctg ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat
     6241 gcatctgatt ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt
     6301 tatgaggcca tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc
     6361 ctgaactaac ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa
     6421 gccagctaat gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt
     6481 gtcctttatt ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac
     6541 agtatagcgg agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc
     6601 cttctcctga acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga
     6661 caagttctgc gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat
     6721 tttctgataa aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc
     6781 ccttcatttg agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa
     6841 ctttttcacc gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc
     6901 tatattcata cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct
     6961 cattgctgta gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc
     7021 ctgccggttt tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag
     7081 aaaaaaaatc ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg
     7141 gtaacgttgt cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt
     7201 acgaaaaata aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt
     7261 taagatattt tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat
     7321 ttcaagaaaa tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac
     7381 caattcaagc gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg
     7441 ccgcttaaat agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc
     7501 atggatagaa aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca
     7561 ttcagctaag tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc
     7621 gctgattgat ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa
     7681 ctctcttgca gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag
     7741 caaatattct ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca
     7801 tctacccata aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca
     7861 tatttagtta tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca
     7921 aaatacccta ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta
     7981 tataaaaaag aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac
     8041 agtttttgtc taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag
     8101 caagaaaaaa agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac
     8161 aagaattatc caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa
     8221 taaatgtatc actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag
     8281 gagagatcca aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa
     8341 aattatgcta cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc
     8401 cacaaactgc tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc
     8461 tcgaaaaact gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat
     8521 ctgtaaaaaa ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact
     8581 tttttctttc agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg
     8641 cactaaaaat gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata
     8701 tctacttgct gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa
     8761 cttcttctga aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat
     8821 actttacttc tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact
     8881 ttaattattt tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga
     8941 ttggtttttt attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga
     9001 cttacttaac tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt
     9061 attttcttgt gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt
     9121 ctacactttg ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga
     9181 aattaagaga aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc
     9241 aataccttag tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca
     9301 tccatttgca gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc
     9361 agttatttcg caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca
     9421 ttacagatca gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc
     9481 acaatacagt gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag
     9541 gttatgagaa caaaacaaag aggatgtgac aaaattcttg tcacatcctc ttattccggc
     9601 tctataattt atgg
//
LOCUS       DACCVZ010000099         9610 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.102, whole genome shotgun sequence.
ACCESSION   DACCVZ010000099 DACCVZ010000000
VERSION     DACCVZ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.102"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            112..306
                     /locus_tag="IVW63_002467"
     CDS             112..306
                     /locus_tag="IVW63_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860709.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            575..874
                     /locus_tag="IVW63_002468"
     CDS             575..874
                     /locus_tag="IVW63_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860710.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(971..1405)
                     /locus_tag="IVW63_002469"
     CDS             complement(971..1405)
                     /locus_tag="IVW63_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7860711.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1637..2347)
                     /locus_tag="IVW63_002470"
     CDS             complement(1637..2347)
                     /locus_tag="IVW63_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAP7860712.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2337..3197)
                     /locus_tag="IVW63_002471"
     CDS             complement(2337..3197)
                     /locus_tag="IVW63_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAP7860713.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3202..3840)
                     /locus_tag="IVW63_002472"
     CDS             complement(3202..3840)
                     /locus_tag="IVW63_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAP7860714.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3855..4154)
                     /locus_tag="IVW63_002473"
     CDS             complement(3855..4154)
                     /locus_tag="IVW63_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP7860715.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4197..5681)
                     /locus_tag="IVW63_002474"
     CDS             complement(4197..5681)
                     /locus_tag="IVW63_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAP7860716.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5701..6162)
                     /locus_tag="IVW63_002475"
     CDS             complement(5701..6162)
                     /locus_tag="IVW63_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP7860717.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6180..7247)
                     /gene="ulaG"
                     /locus_tag="IVW63_002476"
     CDS             complement(6180..7247)
                     /gene="ulaG"
                     /locus_tag="IVW63_002476"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HAP7860718.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7465..8235
                     /locus_tag="IVW63_002477"
     CDS             7465..8235
                     /locus_tag="IVW63_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP7860719.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8508..9335)
                     /locus_tag="IVW63_002478"
     CDS             complement(8508..9335)
                     /locus_tag="IVW63_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7860720.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
BASE COUNT         2997 a         1957 c         1503 g         3153 t
ORIGIN      
        1 aaaactttca aattgattct ttttatttat cataaagata tagatacata atcattttca
       61 cttacatata tttgaatatt aactaaaaac agcaagaaag aagaggatca aatgtattat
      121 gtagaagtaa aaacaaaagg cgtcaaaaac aaacaatatg tgaaaggtat cagtaacgaa
      181 tatcctttac ttggttcatg gaaagaagct gctccttttt ccaaaccatg tgccataaaa
      241 ataaagaacg agctagaaaa agaactgact tgtggtaaag ctgttgtaga tatcatcgaa
      301 aagtaaatcc aatgtataga aaggaagatc acacatgaaa agcgacgtac aaattgctaa
      361 gattatagaa ttagaagaag aagacgcagt gttgacaatt gaaaaaaaat aaatgtttgt
      421 ataccatatg attatttcaa tatgtatcct ggaattggag atctcgtaga gctatatcaa
      481 gatgaatcaa atatacttgt cattcatcat gaaatataga gacttataaa attgtttatt
      541 tttataatgt atcagtatag aaaggaaata aaacatggat tatactgttg aatttgacag
      601 tgaactactt aagcaatttc cacaagaaga acatttcatg tataaagaag caatttccca
      661 caaagtgaca gagtatttgg agcataattt ttttcgtata aagccagtgc gtactcgttc
      721 ggcaaaagga atatacgaga tgaaagtcaa aattaataaa aaaaattatc gcatagcatt
      781 tgctttaaaa aaaaatcatg tgttcatttt ttatattagt tcgaatttgc aaaaaattgt
      841 atttgataaa gaggtgagta aaaaaataaa atagctgagc attggaggat agattgagtg
      901 atactaagtc tatcctcttg tttttctaaa gaactaagct agaatttttt cttttgtacg
      961 ttattatatg ttatttgtca ttaccaaaaa gcaccttttt tcttctagta tctatgacat
     1021 aagaaatacc acccatttcc tttacttgaa caaatcctac tgattcataa aatttttttg
     1081 ttttctcagt atcatctgtc aataattcga tttggactgg tccataacta gtgatcttct
     1141 ccaaagcttc attcaaaagc actttgccta ttccttggcg ctgatacctc ggatgaatga
     1201 ggatatcttg aataaatgcg atcgtcgcaa aatcagtgat ccaacgaacg attccgataa
     1261 tcttcccttc cccattacgc tttatcagag attcagattg ttcaaatgct ctagctaacc
     1321 ttgcagtgtc ttttgtgtaa ttcgtccaac caacgctctt atataattca gaaatctcat
     1381 cgatcataag ggaatcaata ttcatttttt tcttcctttc ttatacaatt ctccctctaa
     1441 taatacagtt ctttgactat ttaatctatc acatataact ctcctgtaaa gattctctcg
     1501 attccttaaa attcctcttt ccttttagaa tgcatacttt ttgataaata aaaaggttgt
     1561 gataaatttt cttcacaacc tctgtttctc tctatcaagt gttatctttt aattttctac
     1621 ccttacccta gcatctctat tgcccgtagt atgcatactt tccatgtttg cgaaaataat
     1681 gtttatctag taaatattgc gggatttcac atatattggg gttgatcagc tcgttttctt
     1741 tggccatcag acaaatttca tctaagatca aactgttttc tactgctttc ataggtgaat
     1801 ccccccatgt gaacggtcca tgtccataga caagtactcc agggacttcg tttggatcta
     1861 attttctttc cttaaacgtc tcgacaatca cattccctgt atgaacttcg taagcttctc
     1921 ttacttcttc tttcgttaat tggcgtgtac aaggaacctt accataaaaa gcatcagcat
     1981 gagtcgtgcc ataagctggc aaatcgcgtc ctgcttgcgc ccacatgacg gagtgcgtgg
     2041 aatgagtatg agtaatagca gttatatctt caaaagtttg atacaaaaca acatgtgtgg
     2101 ggagatctga agatggtttt aagctatctt cttctattat atttcccgac aaatctgtta
     2161 ccaccatttg atctgcttgc atgcattcat atctgacacc gcttggctta atgacgatga
     2221 ctcctagctc acggtccact tcactcacat tgccccaagt caatttgact aatccgtatc
     2281 gcggcaatgc cagatttgct tcaaggacac gttgcttcat tgctgcaatt ttttcttcac
     2341 aagacatcat agccagcctc cttcaattta gaacttaagt agtcttttgc ctgctggatt
     2401 tctcttcgaa agtcttggct tttttcactc cacatttcaa tcagaaatgt tccatcataa
     2461 tctagacgtt tcaaatgtct taataatcca agaaaatcaa cacaaccgct accaaaagga
     2521 acatcacgaa actggcctga atattctttt gttacagggt aagtatcttt taagtggata
     2581 gcagtgatat aatcgatccc tttctcaagt tctcgagccg gattattttc cggccatgcg
     2641 gacaaattgc ctaggtctgg atatacttgt agaaaaggtg aatgaatctg ttctttgatt
     2701 tctaaaaatt ttgaaatgga gttcataaat ggatcatcca tgatttccac ggaaagaatg
     2761 atgccatatt tagaagcttc ctttacgctt tcttttattc cttcgataaa gtcttctctg
     2821 gaattcattg atttctcttc ataataaaca tcgtatccag ctatttggat tactttgacg
     2881 cttagattat gcgccaaatg gattgctttt ttcattagtt gtttcgctgc ttttttcttt
     2941 tctggatcag cagaaccaaa cggaaatcgc cgatgcgcac ttaaacaaat cgaatggata
     3001 cgtacaccgg agctgaacat ctcttctctc agctcagcta tcttttcttc agaccaatct
     3061 aatcgtgcta accgctcatc cgtctcatca atcgacatct cgataaaatc gaagtccatt
     3121 tcttttacaa gggaaaaacg ttctttccat gaaatatctt tgggtaacgc tttttcataa
     3181 atcccaattt gagccatttc cttaccccca gatacgaatg atctcatctt tgaagttttg
     3241 tgcggccttc atcggatcat ttgctgctgt aataccacga ccagtgataa aggtatacac
     3301 atcgatccct tcaaataagt gtaatgtgtg tggatttaat ccaccagtta cagaaacatt
     3361 aaagcctagt tcaatcagtt ttttgatctt cgataaatct ttttcacccc aagtttcacc
     3421 agataacagc gcatcacggc tttgatggta gattacctgc cggataccga tgttatgcca
     3481 atccatggct tgttcaaaag tccaattgcc gtagagttct acttgcaatt cacctatttc
     3541 tttttgtgct gcctccatag ttggaatcgt tgcacaacaa atgactgtca tccagtctgc
     3601 tcctgctttt gcaacattac tcgccactgt tcctccagcg tctgcacatt tcgtatcagc
     3661 gactagtttt ttatctggga acatactgcg aatacagcga atcgcttttt gtccttcctg
     3721 taagcaaaga attgtgccca cttcaataat atctactaca tcaccaactt tcataacatc
     3781 tcctaatgca tgttctaagt cattgtgatc taacgcaatt tgcaaattcg gcctgctcat
     3841 cttagttcct tcctttactt gtttttttgg taccactttg tttcagcaaa tttttcactg
     3901 atttctttga ctgacatcac atttttgata ccgataactg taactccttt tttctctgcc
     3961 tgagtaaaca tattcaaaaa attgactggc gtaaaaacta catcgtattg gccagctgaa
     4021 ctttttccct ctgaaatggc acaatgatgg attttggtaa ttggtacgtt tagttctttc
     4081 attgcttttt ccacacttct catcatcatc aagcttgttc ctgatccatt tgcacacgat
     4141 actaaaattc tcatcttaat ccctccatta tgagtgttgt ctaatcagat tttcttttat
     4201 actctctgct tttctgcata tgtgtcatag tcttctacaa tcaaaaaata accatcagga
     4261 tttttccgat attgtaactg cggaatagcc aataaaccaa tgacaactac ggcaattcca
     4321 gcataaccta ggactttcat gattactgta aacaatggcc aagctgttgc ccagtcgaac
     4381 atcccgatat aaccaccgta tgttgacatc ccaatccatg tagcgaataa tgctgaaccg
     4441 cctacttgta tgattcctga aagaaacggg aacaggcaag cggctttgaa tccacctcgg
     4501 ttattggcat aaactgctat aacggcatta tcaaagaaca acggaatgaa accggctatg
     4561 acgatcgttg gtgatttcaa taaaatcagt aaaccaatca tcaaaaactg tcccaaagca
     4621 ccaaacaaga acccaatcgt taccgcattt ggcgaaccaa agccaaaagt agcagctacg
     4681 tcaattcctg gaacagctcc tggtaaaatc gtgtttgaga ttccttggaa agattgagtt
     4741 agttcatcga cgaatgtccg aacacctaat tgcaagatcg ccagatatac cgcaaaattt
     4801 aaagaagtcg tcataatgta gaataagaaa ctctgccctt cttgcatgaa ttgcgcttga
     4861 atcaaataat ctttgcctag tacaatcaga atgatcccaa agaaaaatag catgagtaac
     4921 gaagtagcaa ccatattctc attgaaaatc gacaagaatc ctggtaattt gatatcttca
     4981 atttttttgt cttgcttgat tgatctattt ttcttttcat cccgcttttt catccactca
     5041 gctaattttg caaatataaa gattccgaac atttgctgat gtgccactgc aaatccggca
     5101 ccttctgtca attcctgcgt gattcctact gttaagttag aagctactgt ccaataacaa
     5161 cctaaaatca gtcccataaa aatcaatgct tgtatcctac ctagatcagg aaagcaaaac
     5221 agtaaaatcc aaaaagcggt agctgcttgt tgaacctgaa cgtttccggt agtgaaaacg
     5281 gaacgcagtt tcgtatattt ctgaaaacgg actaataaga tatttaaaac aaatgcaatc
     5341 agtaataaaa tcatcacatc tccaaaggta cggccaaatg tctccattaa tccagcatcc
     5401 acagcatttt gtccaaaata aggatctgta accatggcat ccaaattgaa ccgttccttt
     5461 agtccaacca agattggccg aaaattattg accaaaccac cagagccaac agtcaaaata
     5521 aagtaaccga ccgttgcctt taagaatcca gcgatgcatt catgaagcgg gcgtttcagc
     5581 aaaatatagc ctaataacac gataaaacca atcaggtatg ctggctgcgt caagatattt
     5641 gttgcaaaat acgtccaaat gcttaacaaa aattccccca tcttttttct cctctatcaa
     5701 ttaattatat tctgccatca caacttggta atcatcgatg gagttcgtag agatgagacg
     5761 ctcaaccaat ccatctgtca ttaataattc ggataatttt tggatatttt ctagatgttc
     5821 ttctggatct tttgctgcga gtgtaaaaaa caaactagcc gttttctcct cattctcccc
     5881 ttcactttca aaacggattg gctgtttcaa cttggtaaat gaaatagctg ttccaaaaac
     5941 accatcactt ttttctgaag aatgcggcat tgctacttga ggtgcgatca caatataagg
     6001 accgtatttt tctacacaat ggatgatctc ctccacatac gtttcatcaa taatttcctt
     6061 atcgatcaat acaagacagc tttcggcgat agcttcacgc caatccgtga tttctttatc
     6121 tgggtaatga atcaattgat ggtcaaaaaa gtatttcagc aagaaactcc ccttctttct
     6181 tataaaaacg acggaaacgg tgtatcattt tcaatcgaga agacatcttc aaatcctcga
     6241 taaaaattaa actcaagatc atctttgttt gtcggataga tgaatttccc gcctacttgc
     6301 cagatataag gtttaaatcc atacttcagg cgatcctttt tgaatttcca aatttcagtg
     6361 atctcttttg gatcagccat aaaattagac caaatatcgt agtggacagg aatcactact
     6421 tttgcattca atgactccgc catgcgcagc atatcaacag aagtaacttt gtctgttatc
     6481 cctcgtgggt tttcaccata ggcccctaaa cagacatcga ttttgtgttc attaccatgt
     6541 ttggcaaata aattggagta atgtgaatct cctgcatgat aaagattccc tcctgatgtt
     6601 tcgaataaat agtttactgc aatttgatcc atctcctgag gcatttttcc ttttaatacc
     6661 tcttctggat cttcacaagt gaccaacgct gtccgatcaa acgcttctaa agctactaca
     6721 ttgatgtctt tgattttgac tgcatcacct ggctttactg taatcgtttt ttcttcagga
     6781 attccccatt tttgccacgt gcgaaccact tcttttggcc caatgaatgt tgcttcagga
     6841 caattttgat gaactgctgc ggctgtatgg atatctagat gatcggaatg gatatgtgta
     6901 acgattaaag cgtctacatt ttttatcgca aaaggatcga ttacgaaagg ctgagtacgt
     6961 aaattaggct gcatattttg aacgccactc atacgcatca tctgatggcc ttttttcatc
     7021 atgccattcc catgactacg ttttcccgtc ccacaccata gatcacataa aatattcgtt
     7081 ccttcatgac ttttcagcca aattcccgta cagcccagcc accacatagc aaaagttcca
     7141 ggatccacta cttctgtttc gatttcttca ttcaagtatg tgccccactc aggaaatgtt
     7201 tctactaacc acttttcttt tgttacttca ttgacagttt tactcatttg cttgctcccc
     7261 ccatatcgtt gttccaactt acaagtaaat attaatgtgt atcagcatcc atgaaaaccc
     7321 ttttatatga ccgtttgttt tttatatgat tttctttcag taatcaatga ttgtttcagt
     7381 ataataaaga cagatatgaa tgtttaaatg aacaactagt caaataaatc catggatcaa
     7441 gatgtccctc aggaggcaaa agtcatgaaa aactcacttg tcaatattga aaaacgtcaa
     7501 aaagaaattt tggaactgct tcagcagact gaacaactat caactttcga attagctgaa
     7561 tcccttgatg tatctattag tacgatacga agagatttaa atttattaga agaaaaaaac
     7621 gagatcatac gcaattacgg ttattgttct tataattaca aaaaccagac tgattttgat
     7681 caatctggtc ctgaaaggat taaacaagcg attgccagag aagctagtaa atacattaac
     7741 gattatgata cgctgtttat caattctagc tcgactgcgt tgaaaacact ggattttctt
     7801 caatctaacc atttgacagt cattacaaac aacgtgaaaa tcaattactc tccgcacaaa
     7861 gataattgta gttatatttt aactggtgga gagatgcgct ttccaaaaga agcactagtg
     7921 ggcgacatcg cattaaatac gatttcttca gtcaatgcag acatttgtat cattggctgt
     7981 agcggagtcg atgtagtaca tggggtcaca acaaagatat taaatgaatc aacgatcaac
     8041 gaaatgatgg tcaacaagac aatcaaatgt aagattttag tcgctgatca tcgaaaaatc
     8101 ggactgacat caaagttcaa gattgctgat atttcagtct ttgattattt gatcactgat
     8161 aaattttgtt ctgaaaaagt attagaggag atcagaaata cggggataaa aaccattcaa
     8221 gtagattcat tttaagaacc aggacgtaaa tatgtaaata ggattatcaa aaaaatgaat
     8281 aacaaattta tcgataaatg aaaaacacgc tacgctcaaa ttgataaagg aatcccaaga
     8341 tgtatccatc caatcgatac catcataatc tattgcttct tttataaccg ttatatgttg
     8401 cctaaatagg aatcaaacaa tatcgaaaaa aggaggtatg acaaaagtca cacctccttt
     8461 tttcgaataa acggtattca aatcagaaca ctgatttcac aaccacttta tttcaggtcg
     8521 ttttcaatca cctttaccgc gtaatcattt ccgttgaaac gcgctatttt ttttgcgtcc
     8581 atatatcttt ctaaataatc atcttctcct aattgcttat ggcaagaagc aatttcataa
     8641 agcaagtatt ccaatgcata agtcgattta tgtttcttat tatactcaat acccttctca
     8701 cataattgga ttgctttatc ataatcctcg attttacggt aataggtggc gatatcataa
     8761 tatacaatgc agaccatcag attatcaaaa tcagtctcac tcaatatttt aagtgtacgc
     8821 tccacataaa ctttcgcaaa atctaattct ccttttgaca agtagatcat tgccacgttt
     8881 gcagctgctt gtaagtgatg gatatctgtt tcggtcgttt gttccaacac ttgattaaaa
     8941 taaaataatg ctgcatctgg ttttttcgca taaagatgat caagcagtcc ttgataaaat
     9001 aaaatttgat ttaaaagatc agaattactt actttttcct gatcgatcgt ttgtaaaatt
     9061 ttataagatt cttggtattt tgatacagaa ttcaatgatt gaatctcatt tatttttttc
     9121 ctgattttgt cttcttctgt ttctactaat atatcggaga tctcgacatt cagctttttg
     9181 caaagcgcac ttaagatatt gatgcctggc gacatattct tgttttcgat attgctgaca
     9241 gttgcttgtt cacaaatgcc ttctgctaat tgtacttgtg ttaacccctt tttctttcgg
     9301 tattctttta gtaatgctcc atctacttta atcaaaacaa tttccttccc tttaaaaaat
     9361 tatttctcct ttatatcata cacaaaaaaa agttctaaac aaccaaaaat gtttagaaca
     9421 gaataaaaat tttaatttta aaataatatt caaattaaac aactggcgta tctgctcctt
     9481 gatttctttt tgtgttatct gaataattat cgtttacagt tataacacat agtgaaaatt
     9541 gtcatggcga gaaagtctaa gaatattttt aaacataact atttctttct tacgtgtgta
     9601 taatgacgac
//
LOCUS       DACCVZ010000100         9442 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.103, whole genome shotgun sequence.
ACCESSION   DACCVZ010000100 DACCVZ010000000
VERSION     DACCVZ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.103"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            59..205
                     /locus_tag="IVW63_002479"
                     /pseudo
     CDS             59..205
                     /locus_tag="IVW63_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            282..611
                     /locus_tag="IVW63_002480"
     CDS             282..611
                     /locus_tag="IVW63_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP7860721.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            601..888
                     /locus_tag="IVW63_002481"
     CDS             601..888
                     /locus_tag="IVW63_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP7860722.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            1174..2031
                     /locus_tag="IVW63_002482"
     CDS             1174..2031
                     /locus_tag="IVW63_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP7860723.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYVEVE"
     gene            2032..2580
                     /locus_tag="IVW63_002483"
     CDS             2032..2580
                     /locus_tag="IVW63_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860724.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            2840..3473
                     /locus_tag="IVW63_002484"
                     /pseudo
     CDS             2840..3473
                     /locus_tag="IVW63_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(3518..4467)
                     /locus_tag="IVW63_002485"
                     /pseudo
     CDS             complement(3518..4467)
                     /locus_tag="IVW63_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300609.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            5069..6913
                     /locus_tag="IVW63_002486"
     CDS             5069..6913
                     /locus_tag="IVW63_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7860725.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            6969..8435
                     /locus_tag="IVW63_002487"
     CDS             6969..8435
                     /locus_tag="IVW63_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP7860726.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSFNWYKEVIETNGASLFE"
     gene            8472..9314
                     /locus_tag="IVW63_002488"
     CDS             8472..9314
                     /locus_tag="IVW63_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7860727.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
BASE COUNT         3246 a         1442 c         1906 g         2848 t
ORIGIN      
        1 agcttaaatc atagataccg taagggattt tattctttat ttaaaacttt gcaacagaac
       61 ccaatcattt gagaagttaa aacctacaca tgaaggtagg tattttagaa gattgaatag
      121 acaacaccgg gttgtttata aggtagatga agatgaacac gtggttgaaa tttattcagc
      181 aaggacgcat tacgagtcac agtaattact tgtaaataca ttatctcgtg gtataatgta
      241 tttactaagt aattacatac tgttagaaat gagggattta aatgattaca aaaacaagaa
      301 aacaaggcaa ttcaatcatg ttgacagtac ctaaagattt taatgttcct aatggagtcg
      361 aagttgaagc aaagttggta gagaatggta ttctttatga atttgttgaa ccacaaaaag
      421 aattttatga ttttagcgaa gatattttgt ctgatataat tgcagaaggc tacgataaag
      481 atgagattct tgtagaattt aagaatagaa aaaacaaaat gcattcttcc tttagagata
      541 ttgctgaaga tacacttact aattctaaag taatgactaa agaggagttg gcaacagaaa
      601 ttggcttatg aaatcgttcc ttcaaaacat gtcattaagt atttaaaaaa gctaaaagag
      661 aagccattga aagaaaaatt tttgaattta atttatgatg aaattgcgat tgatccatat
      721 aagggtgaac aaaaaactgg ggatttatca ggtatttggt ctagtgggtt caaatatgcg
      781 ggcacaacat atagagtagc ttacgagatt atagaaaaca aggttattcc agtattgtta
      841 tgtggaacgc atgaaaactt ttatgaacag ttgaaaaaat taatctagtg atttgttgtc
      901 gttcttaaga aggacggctt cttttttatc gaaaatctga ttcgtctaca tgactaaagt
      961 cgcgagtatt ctctgcttct cgataaatta aataacgtca ttactttgag gaaagctata
     1021 aatcaatata tttcagcttt tccttattta tgtactacct tttacttatt aattataagg
     1081 tagtacatat atatcttttt tttggtagta actaaaaata aatatgttat aatagtatca
     1141 aatgaatatt gctaaaagaa aagaggtagg aacgtggtag cgaagaaata tgtaatcggt
     1201 aattttaaag gtggcgtagg taaaagtacg tgcgcgcaaa tgttagggtt tgaatcagca
     1261 gttaatgaag gaaaaagaac cttgataatt gacttggata tgcaaggaaa tacttctgat
     1321 gtgatgaact taacgcatat gaacttcact aacgaagaag gaggcggaga aggtgaaccg
     1381 attgtttacg aaaatactgt gactgacgtg ttgataaaca atcttccacc taaagaggct
     1441 gtctataaag taatcaataa cctctatata cttccagcag acatgtcctt tgaaatgtat
     1501 gatgattgga tcaaagacca atataatgat tcattatccc aattcaaata tatgaaagaa
     1561 aagctagaac cattatttga tgagtttgac gtcatctatt tagatgtccc accttctatt
     1621 tctgtatata gtaaatccgc gatgtacatt gcggattggg caatcgtcgt cttacagacc
     1681 caagtaaaat cgatgagaaa tgcgatgcaa tatcttgagt atatggactt ttttgtgaaa
     1741 gaatttgata caaatttata tgttgctggt gttattcctt tcatgttgga aagcggtgac
     1801 gcagtagatc aggaaatgta taaacaagcc caagagattt atggggaaca tttgattaaa
     1861 aatgttgtac tcaaaaatgc gcgcttaaaa cgatacgacg gatcaggtat tacgatggag
     1921 aagacaaaga aaggtctctt aaaacaatgg gatcgcaaaa gccacgaatt atttatcagt
     1981 attttgaaag aattggaaga acacgagaat tggtatgtgg aggtggagta attggctgac
     2041 atcaaaggac ttgatatttt tgggaacaac aaaggactcg ccaaaataaa aaaagaagca
     2101 gaagcaaaga aaaagcagca agcaattaca ccatctgaaa ataagcaatt agaagtgcac
     2161 caagttcaag aaataaaaac ttcctccaat gttgaaagac agagtagagg aagaacaaaa
     2221 aaagttggcg caccaatcag aaagtttgat aaggtttatt ccaccaagca tcctttaaaa
     2281 ctgtcgactt tgttaaatgc gacttccaga gttttagtag aaaagtatga gactaatatg
     2341 acaagagatg aattgcttag aaaagcttta gatgagtata ttaaacagaa tcttacgcaa
     2401 gaagataaac aagatttgtt taatgacgtg gtgaaagaac tagacttgtt cagagaaaaa
     2461 tatccaattg ttccagaatt agatgatcgt ggagaaataa taagaactac cagtcagata
     2521 aaacaagata ccgaagactc actgcgcaaa gggtggggaa tgaataataa agttagataa
     2581 taatcaaaga agaactaagt aactaccttt aaacggtagt tacttagttc ttctttgatt
     2641 tgcgtgaaat agaggggatt tatttttctg gttacgtgat taaaaaatcc aaaaaatgag
     2701 cataggaacg gttatgattt tagggtgtgt tttaatgaga tattgtgatt tcattaataa
     2761 gtgtatgata atctgttgtt gagttagtaa ataagtaata gagctaactc taaaataaaa
     2821 ctattaggag gagatgtaga tgaaaaagtt taaaaagaaa atatatttag gattggttgt
     2881 tggggtgagt atgtttgggt tcatggctca tactaaacaa gtaactgcag atactaacca
     2941 aaaagaaagg attatgagcc aattagatga ctctcaaata gagtatgtac ccaatgagct
     3001 aattgtcagt ttaaaggcta cacaaagaat ttcaacagag aaaaataaac cgcaaaattt
     3061 attgggtgta aaagttatgg tggaaaaaga tttgactctt aggacaaatg aaagcgatta
     3121 taataagcga gatcaagtat tattagtgaa attgaacgaa gaaattagtg tggaagaggc
     3181 agtaagaaca tttaatgctt ctgatatggt caattatgca gagccaaact atgtggttga
     3241 actagagccg ttgaatgatg ttgaggagcc aaatacaact gattctttag gaaatcgata
     3301 acgatcctaa ttggagtaaa caagctaatt taagagagat tagcatgcca tccgcttggg
     3361 aagaaaccaa gggttctaag gatgtgaagg tagcggtcat tgattcagga attgattatc
     3421 aacatgaaga tctttctgga aatgtagatg aaagtttggg atacgatttt ttttactttt
     3481 ttcaagaaaa taataattca gaatattctg actatattta tgcaacacta gtgactttag
     3541 gagaaacatc aatagccttg ctaaagtttt tgctttcgct aaagagagta ttttcgataa
     3601 tttgtttttt tctaaaatac ctcgttcctc aatatttggg atatggatat gtatagggat
     3661 tcttcgcata aaggtttcca gaaaatcctc tttgccttct gtagtcgcaa aaactaaacg
     3721 tacattggag gcgtgatgga tagtttcacc gactctagaa taagttccgc catccatata
     3781 aacaaatagt ttctcttgcc cttcaggagg caatctgtgt acttcgtcta aaaacagtac
     3841 tccaccgtct gcatcttgca acaatccatt tcgatcttca tctgcgccgg taaaagcacc
     3901 tttaacatag ccaaatagta tccccgacaa taattcagga ttattatggt attgcgcaca
     3961 attaagtact ttaaaaggag cattctcatg aataacgttc acttttttca taaactgata
     4021 agcagtatga acaaaaaaac tttttccaac tccagtatct ccagtgatca tcataggaag
     4081 ccctcttcca ggatagaaga cagcagtttt catttgttcc accgcatcgg ataagctcat
     4141 atcataccca atcatctttt gtagaatgga atctgtagaa ttgggctcca agtctgtttt
     4201 taattcagat atactttcgt atacatcttt taccggaatc aaaaagtgct cttcaaagcg
     4261 ctctttgatg gcaaataaca ctggacgagt attgatttta aatagaacgt tctttgcaac
     4321 taagtcattg gcaagtttac tggcatttgt tcttcccgtt cttaaaaatt gcgacaggtc
     4381 atttgtgtca aaaaagcact cttctaaatt actgatgcca atttcttcac attttgtgtt
     4441 tgcataagtc actatatcat ttttcatctt ataaacagtc ctttctaaac ttctatccct
     4501 taaataaata gcaaaaaaaa ggaagcaata tcgatatgct gtcctcttaa tttaataaag
     4561 cgctaatcta attcactgta ttatcatttt ttagtagtat agcacaatta tgaatgcctt
     4621 ttctttatat caaataaagt ttatataaaa aacctcatcc tgcaagaaag aaaaaatgaa
     4681 cccattcttt ttatactagg tcttaaaaag acagaacatc tgctagaaga tagaagagaa
     4741 taagagttat atatgttgga agatattctt agaaaaaaga caaaactttt agaacacgaa
     4801 aactatattg aacgaataaa atgaaaaaat gattaaaaaa tcattttatt atttacgttt
     4861 acattctaat atgttaaatt gaatataact taaacaggca tgtgactggt aatgcaggca
     4921 ggacctaaat aagttgaata acaatgtatg cgtttcaata cacgtttgcc ttgttgtcaa
     4981 tttatttagt ttctgcctgt tttttgtgtt gaggatggcc acttcgactc aaaagttcat
     5041 cactcaaaaa agaaaagagg gaaacaccat gaattacaaa caaacagcag aagaagtatt
     5101 gcagtacatc ggtggggaag aaaacatatc ccatttggag cattgctcaa ctcgtttacg
     5161 ttttacgtta aaagacaaca gcaaggtaaa tatgagccag ttagaaaaag tggatggcgt
     5221 tatgggcgtt cgccaaaatg tgcaatgcca agtaatcatt ggaaacgatg ttgttgaagt
     5281 gtatgatgaa gtgaaagcgt tattaggtga caatgtttca aatactgaag aagcaccaaa
     5341 acaaaaacaa aaattaggtt cagttctatt agattttatt atttctattt tccaaccttt
     5401 aattcctgcg attgcaggtg gaggagtatt gaagtccttg ttgctactag cttctatctt
     5461 agggctgatt agtgaccaat ctcaaaccta tcagatttta aatttggtcg gcggggcacc
     5521 gctttatttc ttgcctattc tggtggcaat gactacggct aataaattga aagtcaatca
     5581 attggttgca gtatctgctg tcggtgcatt gatccttcct gaaatgacag ctatgttggc
     5641 ggaaggtgct acattcttat cttttggatt ggataatata gcgtatgcat ctcaagtatt
     5701 cccagccatc ttaactgttt tattttatgc tcaacttgaa aaatggttta caaaagtttc
     5761 accaaaacca attcgtattt tctttgtacc tatgatgagc ttattgatta cagttcctat
     5821 tgctttgttg cttctaggac cattaggtta taatgtagga acagctttct cttctatcat
     5881 tgtgtctttg tacaatcaat ttggatgggt tgcaaccgga gtcttagcag ctgtactgcc
     5941 attaatggtt gtaacgggta tgcataaagc aatgatccct tacgctgttt catccatgag
     6001 tgaattgggt gcagaacttc tttatctccc ggcttcattg gcacacaata tttcagaagc
     6061 tggcgcatgc tttgctgtca gtatcaaaac aaaagacaaa aaattgaaat ctacggctgt
     6121 ttctgcgggt atatctgcat tattcggaat tactgaacca gctctttacg gggtaacgat
     6181 tctgcacaaa cgtgttttat atgccgttat gttttctagc ctgatcgggg gagcatttgc
     6241 aggaatcgtt gcacttcaag cctttgcttt agtgggtcct gggattgcaa gtatcacgat
     6301 gttcgctgac aaagctgacc caatgaatct ggtttgggca tttgcagtat cggggatttc
     6361 atttgtggtt gcttttgctg cagcgttggt tctttataaa gataaagaag ttgtcaatga
     6421 agttgaaact aagatggaaa cggccgttgt ttcagatgct gttctttcaa gtcccgtgaa
     6481 tggaaaagta atctcactat cagaagtaaa agacactgtt ttttctagtg gtatggtagg
     6541 tgatggagta gcaatcattc ctgaagaagg gatattagta gctcctgaag atggagaaat
     6601 cacaatggta tttgaaacga agcatgctat tggtttaaaa acggctaatg gtgcagaact
     6661 tctttttcat attggtattg atactgttca gttagaagga aaagggtttg aggcatttgt
     6721 tcgttctggt gaaaaagtag ccaaaggaca aaagctgatt gcatttgata ttgatttaat
     6781 caaagaagca ggattcgacc ccacagttat ctgtgtggta accaataagg ataattacac
     6841 tatccgttca tttaacctag aaaaattggt aaccaatgat agtgatctct tagctatcag
     6901 tccgatagct taaacacaag atagtgaaaa aaaatatatt gaatgaagga atagaggaga
     6961 atagaataat gacaaacaca acaagttttc caaaaggatt tttatggggc ggcgcgatag
     7021 cagcaaatca agtagaaggt gcttggaatg tagacggtaa aggtctttca gtagcggata
     7081 tggctactta taaaccaaat ttagacaaca aagattttgc tgctcatatg catgtcaccc
     7141 tgcagtctat aaaagaagct agtgaagaca aatctgataa atggtaccca aaaagaaggg
     7201 gcgttgattt ttatcatcac tataaagaag atttagcttt atttgccgaa atgggcttta
     7261 aaaccttgcg cctctctatt gcttggactc gcttgttccc tacaggagaa gagctggaac
     7321 cgaatgaaaa aggggttgca ttttatgaaa acgtctttaa agaaatgcaa cgtttaggaa
     7381 ttgagccgat tgtgacacta tctcattatg aaatgccatt agctttagca gttaaatata
     7441 atggctgggt ggagcgtcga gtaattgatg attttgttcg cttcgctaac gtttgttttg
     7501 atcgcttcgg caaatacgta aaatattggc tgacatttaa tgagatagac agcatccacc
     7561 gtcatccatt tacaacagct ggaattatcc aagagaaaag cgcagaaggt caagaagctc
     7621 aagatatcta tcaagcattg catcatcaat ttgttgcgag tgcgttagtg acaaaagatg
     7681 ctcatgaaaa aattccagga agccaagttg gttgtatgtt aacgaaattg atgacttatc
     7741 cattaacttg cgcaccagaa gacgttgagc tgaccttgaa aaagaactta gaaaataatt
     7801 tttatgcaga tgttcaagtt aagggagaat atcctgctct aatcgaaaag gatttggaaa
     7861 atcggggaat tcagattaaa atggaagatg aagatcgaga aattttaaag aaacataccg
     7921 tagattttgt ttctttcagc tattacatgt ccatggcaga atcagctgat ccaaacgcag
     7981 aacgcacacc gggaaatact gttttagggg ttaagaatcc tcatttgcct tcaacagatt
     8041 ggggctggca aatcgatcca aaaggtttga aaatttcgtt gatcgaactt tatgatcgtt
     8101 accaagtacc gttgatgatt gtggaaaatg gtatgggagc agtcgatcag gtagtagatg
     8161 gtaaaatcca tgatccgtac cgcatcgact actttaaagc acacttccaa caaatgaaag
     8221 aagcaatcga tgaaggtgta gatttgatag cttatactag ctggggacca attgatttag
     8281 ttagtgcagg aacttctcaa atgtctaaac gatatggatt tatttatgtg gatgcagacg
     8341 atgaaggaaa tgggacatat aaccgcttga aaaaggattc gttcaactgg tacaaagaag
     8401 tgatcgaaac aaacggtgca tccttattcg agtagtctcg atctttttaa gcagcgatag
     8461 ggggataatg agtgatttca ataaaaaaag tattgaattc aagtgtggta cttgttgaag
     8521 aaaatggcaa agaaatgatt gcattaggta aagggatagg ctttggacag aaagctgggg
     8581 atgaaatatc aggagataaa gtagataaaa tatttctgcc ttttgaagaa aagaaatctt
     8641 cacaactatt agagttagtt gaagaaatac ctattgaatt ttttgaaatc actcgtacta
     8701 tcgtttttga agcagaaaaa ggattagata aaaaactgaa tcctggagtc tatttaacct
     8761 taacagacca cctgcatttt gcagttgaac gcgcacaaaa aggggtaaat attgcaaacc
     8821 gtttgtactg ggaaataaaa atctactatc ccaaagaatt tcaaattggg aagtacgcac
     8881 tcaccctttt gaacgagcaa tatggaattg atcttcctaa agaggaagcc tcaaacattg
     8941 ctttccattt gatcaatgca caatcggaag atcctgatag cggcgctgga ttcaagtatg
     9001 caaaaatgat cggcgggatc gtcaatttgg tccggtattc gttgcagaaa gatatcgata
     9061 ctaattcgat ccattatgcc cgcttcatta cacatgtacg tttctttgta gaaagatatt
     9121 attctgatgc tttgttggat gatggtgagg aagaattcta caatcaaatg tggatcttat
     9181 acccgtctgc catggaaagc gcagctaaga tcaaagacta cattgaaaaa gtttatcata
     9241 aaacaattcc gaacgatgaa gttgtatacc taggtgtcca catcaatcgg ttgatgaaac
     9301 atgctaatgg gtgagcgctc agtaatacta ttgatgcttt taaaatcttt agagatggat
     9361 tatagtaaaa acaaggtgat ttccagctgt ttgttatcta taagagacat ttaaaaagga
     9421 ttaacgtaag ataataaaaa at
//
LOCUS       DACCVZ010000101         9432 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.104, whole genome shotgun sequence.
ACCESSION   DACCVZ010000101 DACCVZ010000000
VERSION     DACCVZ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.104"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..680
                     /locus_tag="IVW63_002489"
     CDS             <1..680
                     /locus_tag="IVW63_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7860728.1"
                     /translation="YFSRFSLATREAVQWIVIDMYAPYVSLVKKLFPNAQLIIDRFHI
                     VQHIGRTFLNHRVKETTARLKGTSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRAS
                     FKDYLTESEIVDRLLSACPNLRQGYQLYQDILYAVKKRDQSLFEDCLNREVSGLPETY
                     TTTLRTFKKFLPQIQNALHYSYSNGPLECLNNHIKVLKRNAYGFRSFYNFKLRIMIRH
                     GKTFLTK"
     gene            800..1000
                     /locus_tag="IVW63_002490"
     CDS             800..1000
                     /locus_tag="IVW63_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP7860729.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            1076..1273
                     /locus_tag="IVW63_002491"
     CDS             1076..1273
                     /locus_tag="IVW63_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860730.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(1570..3117)
                     /locus_tag="IVW63_002492"
     CDS             complement(1570..3117)
                     /locus_tag="IVW63_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAP7860731.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(3201..4004)
                     /locus_tag="IVW63_002493"
     CDS             complement(3201..4004)
                     /locus_tag="IVW63_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAP7860732.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            complement(4007..4789)
                     /gene="phnE"
                     /locus_tag="IVW63_002494"
     CDS             complement(4007..4789)
                     /gene="phnE"
                     /locus_tag="IVW63_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HAP7860733.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            complement(4786..5565)
                     /gene="phnE"
                     /locus_tag="IVW63_002495"
     CDS             complement(4786..5565)
                     /gene="phnE"
                     /locus_tag="IVW63_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HAP7860734.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            complement(5537..6328)
                     /gene="phnC"
                     /locus_tag="IVW63_002496"
     CDS             complement(5537..6328)
                     /gene="phnC"
                     /locus_tag="IVW63_002496"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HAP7860735.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            complement(6389..7318)
                     /locus_tag="IVW63_002497"
     CDS             complement(6389..7318)
                     /locus_tag="IVW63_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HAP7860736.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            7513..8196
                     /locus_tag="IVW63_002498"
     CDS             7513..8196
                     /locus_tag="IVW63_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HAP7860737.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            8357..9400
                     /locus_tag="IVW63_002499"
     CDS             8357..9400
                     /locus_tag="IVW63_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7860738.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
BASE COUNT         2893 a         1933 c         1869 g         2737 t
ORIGIN      
        1 gctatttttc tcggttttca ttagcgactc gtgaagccgt tcaatggatt gttattgata
       61 tgtatgcgcc ttatgtttca ttggtgaaaa agcttttccc gaatgctcag ttgatcatcg
      121 accgtttcca catcgtccaa catattggca gaaccttctt gaatcatcga gtgaaagaaa
      181 ccacggcacg gcttaaagga acttcccact ctcaacgagg gttagggaaa aaattgaaac
      241 gctattggaa actcctacaa aaagaagaag caaagttaaa ctacgaaaaa agggtttggc
      301 gtgccagttt taaagattat ttgactgaaa gtgagattgt cgatcgactg ttatctgctt
      361 gtcccaacct gcgccaaggc tatcagttat accaagacat tctttatgcg gtaaagaaaa
      421 gagatcagtc attatttgag gactgtttaa acagagaagt cagcggtctt cctgaaacct
      481 atacaaccac tttacgaacg tttaaaaagt ttctgccaca gatccaaaat gcgcttcact
      541 acagctattc aaatggacca ttggaatgtt taaacaacca catcaaagta ttaaaacgca
      601 atgcgtacgg ctttcgcagc ttttacaatt tcaaactacg gatcatgatt cgtcatggca
      661 aaacattttt aaccaaataa acagaacaga aagagagttt cttctttctg ttctgtccaa
      721 attattctaa gatttctctt taccaacatc atttgacaaa gagcctgtat ttattactgt
      781 cgaggacaat ggcatcggca tgattgaaga ggaacaaaaa aacatttggg atcgctatta
      841 taaagccgat ccgtcaagta aaaatacaaa gataggcgag tcaggtcttg gattatcaat
      901 cgtgaaggaa ctagtgcgcc tgcaccacgg ttcaattgaa gtgaccagcc gaaaaaatga
      961 aggaacgacc ttcctgatac aatttccaaa agaaaaataa aattaccagt aaaaaaccgt
     1021 ggagagatag ctgctattga tttttgctat gtcttttctt tgagaggtat ccggtatggt
     1081 ggagtgtctg aaaaataaaa aaatggaggc caattttgtg aaagctgtta tttctggaag
     1141 tattgttttc caagaagaat atcgagatat ggaaaaagat ttcagtaaaa aaggcattga
     1201 attaattgat tatcctcgct catgtccgat cctagacaaa gagtatccag aaatcttgac
     1261 gacttttttt taaatatcgc agcagcggat ttattttttg tatttaatca agatcggaaa
     1321 ggggtattag gctatattgg tgccgcaact ttttcagaaa tgaagtattg tctgatgcaa
     1381 aatcttattc atggaaaaag gatcaaaata gtcttattta aggaaccatc agaggaaaat
     1441 tttttgtttt gatgaggtag atcgctggct aaagaatggc tggatggaaa tcagacagcc
     1501 taacaatttg gcataacaaa ggtgtgggca aaaaactgct cacacctttt tgaatttttt
     1561 atttatatac tacaaaatca cttgaaaatt atgattcact tttgcttcga tgcgtgggtg
     1621 aatattcaaa tagtcggcaa ttaattcggt catgtcgatt tggatttctc ggacaatttt
     1681 ctccgcacca aacatcgcat aatttcctcc gccgattgcc cgatattgat ttgtcaccac
     1741 ttccagcatt tgttgcggaa gaacggggtg acctttaaaa cgaagttcgg taatccgttg
     1801 tccaacaggc tgtttcatat caatagtgta ctgaatccct tcatacatgt cataattgta
     1861 gtactggggc ttaggctgaa taaaggctgg attgaatacg atttggttat tttctacagc
     1921 taaataattt gcggtctgct ccaacgccgc tctcaaatct gcaccattta tttgaatcac
     1981 tgccagagta ttcggataaa tatagttggt gatgacgtcc cgcatcgtga tcgtctcacc
     2041 aaagcctttt ccttcattat tgaataacgc agttccagaa atctctgagc cgctggcaaa
     2101 taattgtaca cgattaataa actctacata gggatgttcc tcaagacgag cctgcatcgg
     2161 atcattaata cgcatatttc cgttcacttt acctaagggt tgatccaacc atttctctag
     2221 tttttcttct accggtacga tcgctgcaag aatttctgga tcaggctctg atttttcaac
     2281 tgagtgtaaa gcaacctggt gatctgtaac aaccacttgc ccctcttttt tctcgacggt
     2341 aagacgaatt tcaccgatga actcgccacg atagcctggt tgaacaacgg gaactccatg
     2401 aaccgtttca gcaattttcc ggtgctgatg accggtgaaa agggcgtcaa tgccttcaac
     2461 ctgctgcaat agctcgtagc cttcattctc tccagttagc gcttctgtgt cctcaccggt
     2521 taacaagtct ttttcaaatc cgccgtggta actaacgatt accaagtctg cttgtttcct
     2581 taatagagga acatattctt ttgctgtttc gacgatactc ttaaacgtaa ttcctgctaa
     2641 ggtttctggc ttttcccagt gaggaatgta ttgtgtcgtt aatcccaaga tagcaatttt
     2701 tacacccacc ttttcgataa tcttataggc gtttccaaag tatggttggt catttttgtt
     2761 caccatattg gctcctaata taggcgcttg ataattctta atcgcttcct cgagataatc
     2821 cacaccatag ttaaactcat gatttcccaa cacttgaaca tcatagctca tttggttaat
     2881 caagtctgta agctctttgg ctgaaccata ttctttagca agataataac tcaaaggaga
     2941 cccttggatg aaatcaccat tttcgatcgt aattaccggt ccatctgctt ttgcccgtaa
     3001 ttccttcagt ttcgacgata ctttagccgt tcctaaggcc agatcggttc tgccggaata
     3061 gtctgttggt gaaacatagc catgcatatc acttgtctct aaaaacgtaa tgttcattct
     3121 gcgtgctcct ttagctgact caaaatagaa aaaccgaagc gtattcagct gttcggtctc
     3181 tttttttgat ttataatgcc ttaatccttc atttgaagtg tttttaaaat gttgcctgga
     3241 ataaagtttt ctgttgtctg gcgaacaatc cttccttgat cgagatgata aaggttatac
     3301 ccatgacgtt cttcaaagcg tacgaagcca tcgccttcat cttcaccaac aaaggacata
     3361 ctcgatacag taaaataggg gatcccatta atttcatcag taaatgtgtg atgggtatga
     3421 ccgtttagga tacagcgaat atcgtaaggt gcgattagct tcaagaaacg ttcggtacca
     3481 ggccattttg gtatactgct ttggtgagac agtagatgat gatgggtgac caagaaaatc
     3541 ggttggtctt tttcttgctc taaggctttt ttcagccatt gaaattgctg atcgtccact
     3601 ataccatctg cgtatccata gcttgaatta tcaaaggaaa tcactgtaaa ctcaggatat
     3661 ttgactatct ggttgtacgg ggcagaagag gcggcttcat cgcaccagcc tacccaaaaa
     3721 tgttctttga tatcgtgatt gcctagagta acaagaatcg tcgtttctcc tagcgcattt
     3781 tccagccaag tcttcaagta tcgataatcg tctatttcgc catcttcggt taaatctccg
     3841 ctgataatca caaggtccaa gggtgtttgc tgcaggagat gatgaatgca ttgctccaga
     3901 gggataaggg gattctgcat cgtagccagc attcccttat agccttcttc acaagcctca
     3961 tactctctgc gaaagtgtat atctgatata tgcaatatat tcattcttat ctcaatctct
     4021 ttcttataat tccggttatt tgatctaaaa taaacacggt tacgactacg ccaatcaaaa
     4081 taatactcac tttgctccaa gaccgagttt gaatcgcgaa tatcaatgga gcaccgattc
     4141 cgccagcgcc aactaagcct aaggtagccg cactacgaac cgctatttca aaatgattta
     4201 atgctaaaga acaataaatc ggcatcaaat aggggatgcg aacaaagaaa atcgtttgcc
     4261 aaaaatttgc tcctaccgca tgcatttctt caacaagtcg ctcatccatc gcttccattt
     4321 cttctgtaaa aagtttgcca agcattccga tctgatggac gccaatcgcc ataacaccag
     4381 caaaggggcc aggtccgacg actttcacaa aaataattgc aaaaactagt tcaggaaaag
     4441 ctcgtaaaac attacagata agcttgccaa tttttgttac ccatggatgt gcttgccaga
     4501 ggttaaccgc actgatcaag gtaatgggaa tcgctaatac cgtagcgatc attgtcccta
     4561 aacaggcgat tccaatggtt aataatagca aactaatcaa atcctcgccg ctgccatcat
     4621 atagaaactg ccaatcaggc tgacctaacc ctctcaaaac gtccattccc atggaaggag
     4681 agaaggtgct taatccagag taatccagag tagcggccga caaaataacg agaatcacta
     4741 aagcaactaa tgataaaagg gttcttctgt tcatttcacg aagcatcata acagggacct
     4801 cctgacacgt tcacttaatt tatcaacgat cgcgacagtt actaggatcg ttagaataat
     4861 gattgaaact cgttcataat tcaaaagcgc aagtgaggaa tttagaataa cgccaatacc
     4921 accagctccg acatatccaa ggacagtaga agcacgaaca ttcacctcaa acgcgtaaaa
     4981 agcatagctc gcaaactgac tcaaaacttg tggagcgatc gaccaaatag cgatttgcat
     5041 tttatttgct ccaacagccg cagcggcttc aatcgggcca aagtcaatgg tttcaattgc
     5101 ttgaaacatt aattgtgaca ccataccaaa agtaaagaca gcgatagtca acacgccagt
     5161 cgcttcacca attccaaaca cagcaacaaa aagcgcggct aaaagcaggg tagggatggt
     5221 ccgtactaaa cctaaaagaa aacgaaagat ggtagaaaga agacggtttt ctgtcactac
     5281 agtggtcgct aaaaaactaa cagggatcgc taaaattaag ccaatgaccg ttccaagcaa
     5341 agacatttga agtgttttca ccataggctc gactaattta ggtaaatagc taaagtctgg
     5401 atgaatgaag cgtgataaaa agacagtcat ttgattggag ttttgaaaaa cctgagaaaa
     5461 atcagctgac gtgatccagg cacttccttg aaaacaaaca attaagaaca gaagaataag
     5521 caggtgttta taccatttaa agtgaacggt ttctttcaag ctcatcgatt tcgcctgcct
     5581 tttcttcaaa gattgcattg ccataaattt gctctaagcg ttcatcggtt aagtcgtctg
     5641 gacgaccatc aaagacaacc tgagcagctt ttaacgcgag cacacgcgta gaaaactcac
     5701 gagccagagg gactgaatgc agattgacaa tgactgtttt atccatcgtt tgattgatat
     5761 tttttaggtc catcataacc ttttgagtcg tgattggatc taatgatgca acgggttcat
     5821 ccgctaaaat aatgggggct tgctgcacga gtgctcgcgc aatggatact cgctgttgtt
     5881 gcccaccact gagctcatca ctgcgtgtct gcaatttatc agacaaacca actttttcca
     5941 gtgcttcctt tgtctgctgg tagtcttcct tcgtaaaaag acctaaaata cttttccaag
     6001 tggagtaata gcccaaacgt ccagatagca catttttctg aaccgtacta cgctttacca
     6061 gattgaagct ttgcgagatt agaccaatct ggcggcgaat ctgtcgcagc tcttttttat
     6121 tcgcttttgt aatagaggtt ccattaatgc gaatatctcc tttggtggtt tctgccaagc
     6181 gattgatact gcgcagcaga gtgctctttc cagcaccact caaccctatg atggaaacaa
     6241 attctccatc ttcaattgtt aagtcaatat ccttcaagcc aacaacgcca ttgggataga
     6301 ccttcgaaac attgtcaaaa ataatcatta tccttctcca tttttttaag tgtaagcaaa
     6361 aaaaagcttg ctgacactta ctgatgtttt attctgctgc ttttttcgtg tagtctctga
     6421 tcgtgtcata ggcagaatca gcagcttctt catagccctg atgcccccac aaagccattg
     6481 cttctttgcc atctttatca tccttcatat ttaagaaggt ctctttaatt ttcgctttta
     6541 aatcttttga catgtcaggc tgtacagcga ttgcgtcatt cggaatatcg ccttttgtca
     6601 ggtacaggac ttttaaatcc ttaaataaat cattatctgg gaaattcgaa gcaaaaacat
     6661 ttcgcgcgcc ttcaaaaaca aacgccgcat ccatttgctt gttcaacact gcggtaatct
     6721 cactcggaat atcattcaca gtggtcatct ttgtatctgc agtaggatca atcccagcat
     6781 ctttcaattc agcgacagga tagatgtagc cgctagcaga gttaggactt aaggttgcga
     6841 tattttttcc ttttaaatca gttaacttat tcaatccgct atcggcacga accaatactt
     6901 ctcctttaaa ggtgttcgta agtttgtcct ttaatggcaa gccagtttct tgatcataat
     6961 cgccgagctg agaagtcagg attgcatctg cagctccagc atcctttgct tgaacatagg
     7021 ctgcaggcgg cataattccg acatcgactt gaccagaaga catcgcttcg acgatcgttg
     7081 aataatcagt agctaacgtc acttctacct cacgatctaa ctttttcgat aaatacttag
     7141 caaatggttt tgcttttgcc tccatactac catcattgtt tgttggaacg aattgaacaa
     7201 ctaatttttc tttgctctct ttttctgagc tgctacttgt attcccagaa ccgcaggccg
     7261 ccaaagtggt caataacatg actccgatga acccttttgc taactgtttg aactgcattt
     7321 ttctcctcct gttggatata atttctaata cgtctaaatc atagcaggga atcaaaatca
     7381 atgaagtgac gcacgtccta ttttacacaa cttttacata caatttacaa acaattataa
     7441 ataattattc gtattgagcc gaaaaacaat ctaagctata ataaagaaaa acttcttaga
     7501 ggtgacgatt tcatgaaaaa aatccatgat acgaagcaat taactgctta cgttgagaag
     7561 cacaacctgc aggattatat ggattcagat atattggcaa tggcttcttt actttttttt
     7621 gaaaaggaag agcacctcat tcaaacggga aaaacctcag attatttgta ttttttagtg
     7681 gatgggacgg taatggtgta ctcgtattct tctgatacac aaaatatttg catcgattac
     7741 gcaaagcccg ctacaccact cggcgaagcc tcttcattgt gggaattatc gccgaaaagc
     7801 agcgttaaag cagtgactaa gtgcatctgt atcagcattc cgctaaatca atatcgaaca
     7861 cagcttcaaa aagatgttcg ctttttgcag aatatttgcc agttactaag ttatcgttta
     7921 aattccggga taaatttggc gaactcactg acagaacctg ttgaaactcg tttagcaaag
     7981 tttattttga cccatcacga aaacgaacgt ttctcatttc ggttaaccac ctgcgcctca
     8041 atcttaaatg tcagttatcg acatctttta cgaacaatca cgaattttcg tgaggagaat
     8101 attatcgaaa agaaaaagaa ttattacttg attcatgata tcgaagcttt agaggactta
     8161 gctgagaata taagtagtcc agtaaaagca gaataacagc tataaaaaaa cagcagtcag
     8221 aagtgattgc tggttttttg atagtggaga aattgggaaa cggaaaatct tcgttgaaga
     8281 gtagtgttct atatattggt atgctatact tttaaaagtt caatgtgtca agacacataa
     8341 aaaggggaga aaaattttga agaaaatact tgtttcattg ttgtttttgg tgtcattagt
     8401 aacgttagtc ggctgtagtc agtctcaggg ggagaagcaa agtgaaaaag agaaaagtaa
     8461 aatcgctttg gttcttggat ttggcggggt tgatgaccgc tccttcaatc aagctggctg
     8521 ggaaggatta gaggcttggg gaaaagagaa aaagctgaca gcaaaaaaag attttacgta
     8581 tatagaaacg aacaatccag aggataacag taccaatatc gatcaggcaa tcagaaacgg
     8641 ctttaccacc attattagct tgagctactt gcaagcagag gaactggaaa atgctgctaa
     8701 agataatcca aagttgaaat ttgccttggt agatggtgag attactggga aaaagaatat
     8761 ctcatcagca acctttaaag atcaagaaag tgcgtattta gcaggactag ctgccgcata
     8821 tacgacaaaa agtgatcaag taggctttat tggtggaatg gaagggcccg tgatccaacg
     8881 tttccaaagc ggatttgaag ctggcgttaa ggcaggggcc acagcactga acaaggaaat
     8941 tactgttaac gtacaatatg ctgcatccta tgattcgcta gataaaggaa aagctattgc
     9001 tgcttctatg tacaaagagg gagtcgatat tctttatcag gcggcaggaa gtactggagc
     9061 tggggtgttc caagaagcaa aagcccgcaa tgaaaacgac tatagcagaa aagtatgggt
     9121 gattggtgta gatcgcgatc aagcggatga aggggattat aaaatggaga acggcgagac
     9181 agggaatttc acgttgactt ctacaaagaa aaatgtcggt gcagaagtca aagaatttgc
     9241 agaaacttct cataacgata aatttcctgg cggcaagcat ttgacctttg gtttgaaaga
     9301 agaaggggta gatctgacaa aaggacaatt atcagaggaa gcctatcagg cagtttcaga
     9361 cgcaaaagag aaaatcatca gtggtgattt cagactgtag acaaagtcca ttttatggat
     9421 gatgtctaca gt
//
LOCUS       DACCVZ010000102         9148 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.105, whole genome shotgun sequence.
ACCESSION   DACCVZ010000102 DACCVZ010000000
VERSION     DACCVZ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.105"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(223..708)
                     /locus_tag="IVW63_002500"
     CDS             complement(223..708)
                     /locus_tag="IVW63_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAP7860739.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            1188..1829
                     /locus_tag="IVW63_002501"
     CDS             1188..1829
                     /locus_tag="IVW63_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP7860740.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            1848..2483
                     /locus_tag="IVW63_002502"
     CDS             1848..2483
                     /locus_tag="IVW63_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP7860741.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2501..3316
                     /locus_tag="IVW63_002503"
     CDS             2501..3316
                     /locus_tag="IVW63_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP7860742.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3635..5071
                     /locus_tag="IVW63_002504"
     CDS             3635..5071
                     /locus_tag="IVW63_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP7860743.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5260..7707
                     /locus_tag="IVW63_002505"
     CDS             5260..7707
                     /locus_tag="IVW63_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAP7860744.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            7937..9004
                     /gene="rlmN"
                     /locus_tag="IVW63_002506"
     CDS             7937..9004
                     /gene="rlmN"
                     /locus_tag="IVW63_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAP7860745.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
BASE COUNT         3077 a         1526 c         2021 g         2524 t
ORIGIN      
        1 attccgattt ataatcgaaa aaagaagcat ttttatatat gcttcttttt tcgtagaatc
       61 aataaatatg gatttggcta actatggaag aatactcgta ttagttttca gcgttcatac
      121 tagttgttac attgtttgat tggccaaaag aatttctgat atattttgtg ctaaataaag
      181 aaaaagacgc ttgaattggg aaataagaaa actactctat cattacaaat tttcataaac
      241 tggcagatgt tctaagtaaa caagtatctt ttcaaagtcg gaaaaatcca taatcaacgt
      301 agtggtattg atatttggat gaaagcctac ggtatcttga cgatcaatag cagcatcgat
      361 cacgacttgg atttttttct ctttgtcgtg catcaatgct aatggagtca ctgtacctgc
      421 tggaacgcct aggaggtcag gaagctgttc ttcagaaaca aaagataagc gcttttcttt
      481 taattgttca gctagttgtt ttaaatcggc gtgcttttca tcaggcaaga tgacaagata
      541 gatttgtttt ccttttcttg atttcaataa tagatttttt acttgcggac caggtaggga
      601 aaaagggaca tttttgactg acgtaatcgc aggatgatcg actttttgaa aagagatacc
      661 cagttttttt agtagttcat aagcttcttg ttcggttgca cgactcatcg cgcatcaccc
      721 tccttttttt attagtgtat cataaaaaag agttgacaaa tgaaaaataa tcatgtaaat
      781 tacacgtaaa gttaaaacaa atgacatcga aaagaagagt agccgttagg tgtttttaga
      841 gagtctctgg ttggtggaaa gaggcagcag ttaaccgtga aacacatctt ggagtcgatt
      901 ttctgaagcg tatagtagga aaatccgggg agcccgttac agctgcggtc gttgctagat
      961 gaccagataa ggctggcttt tccgtgagga gtcggtaaaa aaaggtggaa ccacgtgatt
     1021 aacgtccttt gatcttcgga tcaaaggact ttttgttttc atctgaacgg caacgactgt
     1081 gtgaggtttt ttctgcaagg aaaaaataaa cagaggtgga accacgtata atacgtcctc
     1141 ttggcatttg ccaagaggat ttttttattt taaaggagga aaagaagatg gagtatttga
     1201 ttgaagttat gccgcaatta ttagtaggag cactcacaac attgaaatta tttttattta
     1261 ccttgattgg ctcattacca ttagggattg ttttagcatt aggattgtct ttgcatttta
     1321 agccgctacg ctacttgctt caaacatatg tatgggttat gcggggaaca ccgctgttgt
     1381 tgcaactgat ttttattttt tatgggttgc cgacgattgg gatcgttttt gatcgtttcg
     1441 aagcagcact cattgccttt atcttaaact atgcagctta ttttgcagag atctttcgtg
     1501 gagggataca atcgattcct caaggtcaat atgaagcagc gcaagttttg caattaagtc
     1561 cctttcaaac ggtgacgaaa atcgtcatcc cacaagtgac aaagattgtt ttaccttctg
     1621 tagggaatga agttatcaac ttggtcaaag attcttcctt gatctatata ttaggtttag
     1681 gtgacgtaat gcgtgctggg aaaatcgcga tggaacgcga cgcgacttta ctgcctttgc
     1741 taggcgtggc aatcatctat cttacattga ctggtattct aacaatcgta atgaaacaag
     1801 ttgaaggaaa attaaattat taccgctaac tgataggagg aagaaatatg attgaattga
     1861 agaaagtgaa caaagcattt ggtgaaaaaa aaataatcaa agatttgaat ctaatcattc
     1921 cagatgggaa aacattagct atcgtaggtc cttccggtgg cggtaaaacc acgcttttac
     1981 gtatcttggc tggcttagaa agttctgaca gcggagaatt ttatttagac ggtgtaccgt
     2041 tcaacccatt cgagcttaaa atgaaagaac aagttgtagg agtcgtattc caagacttcc
     2101 agctatttcc acatctgaat atttttgaaa acattacctt agcaccaaaa atggtattga
     2161 aacagacaaa agaagaatac accaaaaaag cagaagaatt agcggcttca ttagggatta
     2221 gtgatttatt gaatatctat ccttatcagc tttctggcgg acaaaaacag cgggtagcga
     2281 ttgccagagc attggctatg aatccacggg tattggctta tgatgaacca acaagtgctt
     2341 tagatcctga attacgccag caagtcgagc gtttgatcct atcattgaaa gaagatgggg
     2401 taacccaaat tattgtcacc catgatttag tatttgcaga aaatgtcggt gatcaattac
     2461 taaaagtttc cccaattcat taagaaagga gaagatagag atgaaaaaaa ccagttttct
     2521 attcgctttg atcgcaggtc ttcttctttt tgcaggctgt tcgaacaaaa aaacttcagc
     2581 agataattgg gcgactatca acgaagagaa aaaaatcgtt ataggtttag acgatacatt
     2641 tgttcctatg ggatttagag ataaagacgg gaagctcaca ggatttgata ttgatttagc
     2701 caaagcagtc tttgaacaat atgggattac ggtagacttt cagcccattg actggtcaat
     2761 gaaggaattt gaactgaaca atggaacgat cgatttgata tggaacggct attccaaaac
     2821 gccggcaaga gaaaagaaag tgcaatttac aaaaccttat atggaaaacg atcaagtgct
     2881 gatcacacct aaagaatcag gaatcacaaa ctttggacaa atgaataata agagattagg
     2941 tgcgcaaaat gggtcatctg gttatgatgt atttacgaaa caaccagaag tattaaaaga
     3001 gatagtcaaa aaccaagatg ctgttttgta tgatagtttt aatgaagcat tgatcgatct
     3061 gaaaagcaga cgggtcgatg gtctgctgat ggataaagta tacgcagact attatttgaa
     3121 acaaagaaac gaactagaag acttcaacat aacaaaaggt tcttatgaga gtgaggattt
     3181 tgcagttggt gcacgcaagt cagatagtac attagtgaaa aaaatcaatg aagccctaga
     3241 tcaactagag aaaacaggtg aattccaaaa aatatccgat aaatggtttg gcgaagatgt
     3301 tacgccgaga aattaacaaa taggggactg tgacaaaaga cgtgtcacag tccctttttc
     3361 cgaataaaca gtgttctcct gccaactcct tgtgactcgg agctgaatgg caggctcaca
     3421 acctcttggt aaacggtgtt caaaagccag tttttcggta ttaagccaaa tttatgcaaa
     3481 aatgtagaaa gccattttca caaaattttt cttactactc gaaactaagc gactttttca
     3541 caacctcctt tacataattt tattttgttg tggaaggggt ttcgtgttat tctaaaagag
     3601 gaacgattga aggttatagg aaaggaagag atgaatggaa cacaaagaac ttacctcatt
     3661 tccaaaagat tttctgtggg gctctgcttc tgcagcgtat caagtagaag gagcttggca
     3721 agaagatggg aaaggagaat cagtctggga tcgatttgta cggatacctg gaaagacatt
     3781 taaaggaacg aacggtgatt tggcagtaga ccactatcat cgttataaag aagatattgc
     3841 tttaatgaaa gaacaaggtc tgaaagctta ccgcttctct gtagcttgga cacggatttt
     3901 tcctaatgga cgaggagaag tcaatcaagc tgggctcgct ttttatgaga gattgatcga
     3961 cgaattgatt gaaaacgata ttgaacctat gttgacttta tatcattggg atcttccaca
     4021 agcattgcaa gatgaatata atggttggga atcacgtcag atcattgaag atttcactca
     4081 ttatgcagaa acattatttg aggcattccg cgggaaagtc cattactgga ttagtttgaa
     4141 tgaacaaaat atcttcactt cattaggtta tttgttagca gcacatccgc caggtgtgac
     4201 agacccgaaa cgaatgtatg aagttaacca tattgctaat ttagcaaatg catctgtcat
     4261 caataaattt cacgagttag aaatgcctgg aaaaatcgga ccaagctttg cgtatacgcc
     4321 aaattatcca attgacagta atcctgaaaa tgttctggct gctgaaaatg cagaagacct
     4381 gatggccaat tattggatgg atgtctatat gtggggaaaa tatccgattg ctgccatgag
     4441 gttcttagaa gaaaaaggat gggcaccaac gattgaagct ggcgatgcag aattgctaga
     4501 atctgctaaa ccagattttc ttgggatcaa ttactatcaa acggcgacga atgcattcaa
     4561 tccattaaac ggagttggtg ctggaaaaat gaatacgaca ggaaaaaaag gttcatcaga
     4621 agaaactgga gttcctggaa tgtataaaaa agttgagaat ccatttgtcg aacgaacaaa
     4681 ttgggactgg gagattgacc cagaaggatt aaggatcgga ctgcgtcgta tcacaagccg
     4741 ttaccgcatg ccggtactga ttacggaaaa tggcttagga gagtatgaca agttgacaga
     4801 agataaacaa atccatgacg actatcgaat caattactta caaagccacg tcaaagccat
     4861 caaagaagca atttcggatg gagcagaagt cctaggctat tgcacctggt cttatacaga
     4921 tttgcttagc tggctgaacg gttatcaaaa gcgatatgga tttgtatatg ttgatcaaga
     4981 cgaaacacaa gaaggatctt tggaacgata taagaaagac agttattact ggtaccaaaa
     5041 actgattgaa gaaaatggag agaaccttta gttcacatac ttaaaacaag aaggtacggc
     5101 tggatatggc cgtgcctttt cttgataaaa tcatttagaa attaagaaaa actgtaaaat
     5161 aagctgaaaa atgaaagaaa gcgtcagttc tttcaaacaa aactttagtt cccttacttt
     5221 tttttgtata atgaaacttg atgaaatgag ggataataaa tggcacaaaa gaaacggcct
     5281 actaaaaaaa ggaaaaagac gaaaaaaacg aaaaagcaaa aacagcagca ggaacaaatg
     5341 ctgacgattg gtgttgggtt tgccttgatt ttatttgctg tcttcggctt tttaaaatta
     5401 ggttttttag gaatattgat tgcaaacggc tttcggatca ttgcaggaaa tacttaccaa
     5461 atcctctgtc ttttattagc cgtattagga ttttggattg tcattaagaa tacagagttt
     5521 tcaattggta aaaaccgacg ctggtttggc ggcatactct tttatttcgg tatcttatta
     5581 ttgttacatg cccatttatt tggcaaactc catactgggg aaccaaatat catggggacg
     5641 acatgggatt tgttagccag tgatataaaa caaagtcaag tagacaataa cgttggtggt
     5701 gggatgattg gagcaatcct ttatcatttt acttacttct tgattgcaca gcctggaagt
     5761 tatttagcag cagtgctatt actggcagga ggagcattcc tgttcagtaa tctggaaggc
     5821 tatcagctgt taaatggtat ccaatcaatt ggagaacgag tacaggaatt attggaaggt
     5881 gatcctgcca agcaagctcg aaagcaagcg gcaaaggaag agagaatgaa acagcgcgca
     5941 gaagcgaaag aagcaaggcg cttagctgca aaagaagctg cagaaaaaga agctgcagaa
     6001 tatgagaaga aaaaagcggt gagccagcaa agggaaaata ctgctgatga atggcaggaa
     6061 ccagaaaata cagagccgga gcagctaagt tttgttccaa tcgacagttt tcaagaaaat
     6121 atccatcctg cgaatctaga gaaaccagta ccagatacac caaaacagac caatacagca
     6181 gaaggttttt cagatgagtt gccagaggat gacggtacct cattagaatt tgagattgaa
     6241 gcagaacagg aaaatcaaga ctatgaatta ccgacagttg atttgcttga ttctatacca
     6301 actgtggatc aaagtgatga gtataaaaaa attgaaaaaa atatcggcgt attagaacaa
     6361 actttccaaa gtttcggtgt cgatgccaag gtcgtcaaag ccagcttagg accatccgtc
     6421 acaaaattcg aagtccagcc ggctgtaggg gtaaaagtaa gtaaaattgt gaacttaaca
     6481 gatgatatcg cgcttgcttt agcggcgaaa gatgtccgga tggaagcacc gattccaggt
     6541 aaatcactga ttggtattga agtaccaaat ggaaagatca gtatggtttc ctttagagaa
     6601 atcatcgaag cacaaccaaa ccacccagat aaattactag aagtaccttt aggacgtgat
     6661 gtttctggac gggtacaaac ggctgatctt tcgaagatgc ctcacttact cgtggctggt
     6721 tcgactggta gtgggaagtc agtagcaatt aatgggatta tcacaagtat attaatgcgt
     6781 gctaagcccc atgaagtaaa actgatgatg atcgatccga aaatggttga attgaatatg
     6841 tacaacggca tacctcatct gttgacgccg gtcgtgacga accctagaaa agcagcgcaa
     6901 gccttacaaa aagtagtaca agaaatggaa gaacgatatg aaaaattcgc ggcaaccgga
     6961 gtaagaaata tttctggtta caatgaattt gttcaacaga aaaacttgga aaacggaacg
     7021 aaacatccaa ccttaccatt catcgtagtg atcgtagatg aattagctga tttgatgatg
     7081 gtagccagca atgaagttga agatgcgatt attcgtttag cgcaaatggc tcgggcagcg
     7141 gggattcata tgatcctagc tactcaacgt ccaagtgtgg atgttatcac aggaatcatc
     7201 aaagcaaatg taccttccag aatggcattt gcggtatcaa gcggtacaga ttctcggacg
     7261 atcattgatt ctaatggggc agaaaagctc ttagggcgag gagatatgct attcttgcca
     7321 atgggtgaga ataaaccgat ccgtgtgcaa ggagcattca tttctgacca cgaagtagaa
     7381 cgggtcgttc aatttgttac agatcagcaa gaagctcatt atgaagagaa aatgatgccg
     7441 acagatgaag ttgaaacgac aggtgctcca gaacagccac aagatgagct gtttgaagaa
     7501 gcaaaagcac ttgtcgttga aatgcaaacg gcaagtattt cccttctcca aagaagattt
     7561 cggatcggtt acaaccgagc agcacgttta gtagatgaac tggaagctca tggagttgtt
     7621 ggcccgtcag aaggaagcaa gcctcggaaa gtattcattg agcaggaaga aacatcagaa
     7681 acgttgccgg acgataatga catgtaaaac ttgtgtgatg aagggttgaa aaacgaataa
     7741 ccaataaaaa gacaaggcat gatgatacca aaagaaaaaa tggttttttt ccatcttttc
     7801 taatacggta tgatgtcttg tctttttagt ttttgtgaga ttaaagttct attcgattta
     7861 tttgtgaagt attgcattaa ggaaatgaat catgtatagt atgtagcgaa actttgagaa
     7921 aaagagggaa aatactttgg aaaaacagtc catttatggc ttgacgaatg aagaattaat
     7981 caattggttt atagaaaacg gcgagaaaaa attccgagct gcccaagttt gggaatggtt
     8041 gtatcaaaaa cgtgtaagta atttcacaga aatgacgaat ctatcgaaac aattgatcga
     8101 aaaattatcg gagcatttta tcatcaatcc tctaaaacag atggtcgtcc aagaagcttc
     8161 ggatggtaca gtaaaatatt tgtttgaact ccctgataaa aacatgattg agactgtact
     8221 gatgagacaa gaatatggct tgtcagtttg tgtgacgaca caagtaggat gtaatatcgg
     8281 ctgtacgttt tgtgcaagcg ggctgctcaa aaagaaccgt gatctgactg ctggagaaat
     8341 tgttgcacag atcatgatgg tccaacatta ttttgatgag cgcaatcttg gcgaacgcgt
     8401 ttcacatgtc gttgtaatgg ggatcggtga gccatttgat aattacgaca atgtaatgga
     8461 ctttttgcat atcatcaatg atgccaaagg attggcaatt ggtgctcggc acattacagt
     8521 ttccactagt ggattagcac acaaaatcaa ggaattcgct aataacggct tgcaagtcaa
     8581 tctggctatt tccttgcacg cgccgaataa tgaggtgcga acatcgatca tgcggatcaa
     8641 ccgaagtttc ccaattgaga aattgatgga agctgtggat gagtatttag agaaaacaaa
     8701 ccgtcgaatc acgtttgaat atatcatgtt gaatcaagta aatgatagac cagagcatgc
     8761 gcaacaatta gcagatctat taaaagataa gaaaaaatta gcatatgtca acttgattcc
     8821 atataatcca gtcagtgaac atgatcaata ttctcgcagt ccaaaagctg atgtattgag
     8881 attttatgat gtattgaaga aaaacggcgt aaactgtgtg atacgtaaag aacatggtac
     8941 agatattgat gcagcttgcg gacaattgcg aagcaagcaa atgaaaaaaa cagttgccaa
     9001 ataatcgtat cctactcgtt ttttcaatta ccataaaagg agcagttttc ttaattaagg
     9061 aactgttcaa cttaaataag agaaaagatt ctatagcgaa agctataaag ctttttttga
     9121 caagaaaaac cctcatcaag caaagaaa
//
LOCUS       DACCVZ010000103         9078 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.106, whole genome shotgun sequence.
ACCESSION   DACCVZ010000103 DACCVZ010000000
VERSION     DACCVZ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9078
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.106"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..1101
                     /locus_tag="IVW63_002507"
     CDS             <1..1101
                     /locus_tag="IVW63_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP7860746.1"
                     /translation="KKETIVRFEQYNHMPLVTRLKKQRYTCKNCRTHWTAQSYFVRLS
                     HSIADHVRYKIASLLTEKVSLSFIAKSCQVSLTTVTRTLKEFKSYLPKPSKKILPRVL
                     MVDEFRSHASIEDKMSFICADGETGNLIAVLPTRKLPRLTSYFLGCTNPEEVEFLVTD
                     MNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQALNELRIREMNELRKAGQKSQAEKLKK
                     NWRFLLKNRASINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSAPLKEAYPFFHELV
                     EAFRDKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITSAMIYPYSNGKIEAKNT
                     HIKTMKRVSYGFKSFENMRIRIFLINQLINVR"
     gene            complement(1280..1615)
                     /locus_tag="IVW63_002508"
     CDS             complement(1280..1615)
                     /locus_tag="IVW63_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP7860747.1"
                     /translation="MKMNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSK
                     YHTKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQ
                     RLEERMEEL"
     gene            complement(1599..1871)
                     /locus_tag="IVW63_002509"
     CDS             complement(1599..1871)
                     /locus_tag="IVW63_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAP7860748.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2322..3125)
                     /locus_tag="IVW63_002510"
     CDS             complement(2322..3125)
                     /locus_tag="IVW63_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAP7860749.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3103..4227)
                     /locus_tag="IVW63_002511"
     CDS             complement(3103..4227)
                     /locus_tag="IVW63_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860750.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4243..5058)
                     /locus_tag="IVW63_002512"
     CDS             complement(4243..5058)
                     /locus_tag="IVW63_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7860751.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5048..5929)
                     /locus_tag="IVW63_002513"
     CDS             complement(5048..5929)
                     /locus_tag="IVW63_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7860752.1"
                     /translation="MSEMKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAP
                     TKEFVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNL
                     YKPLFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAG
                     ITAWKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVM
                     TIVQGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAV
                     FLGVIFKFVEKGVYYEN"
     gene            complement(6005..7294)
                     /locus_tag="IVW63_002514"
     CDS             complement(6005..7294)
                     /locus_tag="IVW63_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002581297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7860753.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7522..8166)
                     /locus_tag="IVW63_002515"
                     /pseudo
     CDS             complement(7522..8166)
                     /locus_tag="IVW63_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
     gene            complement(8643..>9078)
                     /locus_tag="IVW63_002516"
     CDS             complement(8643..>9078)
                     /locus_tag="IVW63_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7860754.1"
                     /translation="ECVNCPLLNQCTISKNHQRVITRHVWGDLMDEVEHLRLTDLNKS
                     IYKKRKQTIERIFADAKEKHGMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKE
                     PLFFCSKIRNEVDKKLFQARVTSLEQLLSTVWLSVRTAFFVG"
BASE COUNT         2793 a         1943 c         1439 g         2903 t
ORIGIN      
        1 aagaaggaaa cgattgtccg ttttgaacaa tacaatcata tgcctttggt tacgcgccta
       61 aaaaagcaac gctatacctg taaaaactgt cgtacccatt ggacggctca aagttatttt
      121 gtccgactca gccattcaat cgcagatcat gttcgatata aaattgcttc tttactgact
      181 gaaaaagtat ctttgtcttt tattgcgaaa agttgtcagg tatctttgac taccgttact
      241 cgtacattga aagagtttaa aagctattta ccaaagcctt ctaagaagat tctccccaga
      301 gtattgatgg ttgatgaatt tcgttcgcac gcttccatag aagataaaat gagctttatt
      361 tgcgcagatg gtgaaacagg aaacttaatt gctgtcttgc ctacgcgtaa attacctcga
      421 ttaacaagct atttcttagg ctgcaccaat ccagaagaag tagaattctt agtcacagac
      481 atgaacgccg cttacttcca gcttaccaaa cgtgttctgc caaatgcgaa agtagtgatt
      541 gatcggtttc atattgtcaa acacatgaat caggcactca atgagttgcg tatccgtgaa
      601 atgaatgagc ttcgtaaagc aggacagaaa agtcaggcag aaaaactgaa aaagaactgg
      661 cgctttctgc taaaaaatcg tgcaagcatc aaccattatg agtacaaaac atggaaaagt
      721 ttccgagcac caaaataccc atttctcact gaagcaatga tgattgatcg attgcttgag
      781 ttttctgcgc ctctaaagga ggcgtatccc ttttttcatg aattagtcga agcctttcga
      841 gacaaagacc ctgacttatt tttctcctta ttggcagaac ttcccgaaac gttagatgac
      901 ggctttcggg agaagcttca aaaccttctg acctatgaag aaggtatcac cagcgcaatg
      961 atctatcctt attccaatgg aaaaattgaa gcgaagaata cccacataaa gacaatgaaa
     1021 cgagtatcct acggatttaa atcattcgag aacatgagaa ttagaatctt tttgatcaat
     1081 caattaatca atgtaagata acaaaaaatc tgaaccagaa tgtggttcat tctgacccgg
     1141 atttgatttt gcacaactca tcagtcctta ttgacaaaga gccaaaaatc tgagccagaa
     1201 tgaggttcat tctgacccag atttgatttt gtacaaccca tcagtcctta ttgacaaaga
     1261 gcccttcttt ttagtattat tataattctt ccatgcgttc ttccagtcgc tgtaaatcgc
     1321 ttggacttaa ttccccaatt tttttccatt tgaccttttt gttgtttttg ggtaattcgt
     1381 ttagagttcc tacgtcaatc caagattctt tttttagtcc tgcctgtttc caatccctta
     1441 tttcaacgta tttcagcttt attttatcgg atttagtatg atattttgaa gtaattgaca
     1501 gaaacgaaat tgtgtccagt ccatttttta gaatatagac aggccggcgt ttaccgccct
     1561 ctgcagctgt gaaagcaacg tagacggttg ctatatcatt agtattcatc ttcattgaac
     1621 cattcttcaa ttttttcgtc agtgtctagt ttttggacag gcaatttttc cgctaatctt
     1681 tgaatattat ggattcgttt acttttttcc gacaattcaa tagaaaatgg gatttttcct
     1741 tgctcaacaa tttgcttata aaaaacggtg acggctgttt tggggctcat gcctagttca
     1801 tcaataatgc tttctgcttc atttttcaat ttttcgtcca tagaaatttg taacttagcc
     1861 attttctcca cctctttctg acaaacacat tatatcacgg aaagagttca aatggaatta
     1921 atacaactac ttttgaactc cttgaaatgc agtgtattta tctaaatata aggaaaggat
     1981 atagtgctaa atggccttga tagatagaaa agtttcaaaa tccgccacag cgataattga
     2041 agcgaacact caacgacaca cagaacagga aaagactcct aaaagaacca aattaactag
     2101 gacgtgtctg aaaactccac aaagatgtgg tatgctctgg taaaaaacga atggcacaac
     2161 cacgaagacc gatatggttc ttggaaaact ttctccaccc tttttgtaat tggagggata
     2221 gtggtttatt gatagcgatt ttccaagttc ttcaagtgga accagacatt gagcaccacg
     2281 gctaaaaagt gaatgaagtc tttattttta atcaataatt tttaatgatt accagtaatt
     2341 ggttttttca tgcgccctat ttctatttga tgtggagtta aataatgctg ataagtaaaa
     2401 atttttccgt caattaaact gccactagtg aatcctgttc tattggtaaa aagagaatag
     2461 tctgggtatt catctacacc aaatgataaa gattcagcca taaactgttt tttaccagca
     2521 aattcagcac tgctaccttg atggatatgt cctacaaaaa tacctaaaat atcactttcg
     2581 gcaatcaatt cagcaaaacc ttccggaact tcagttacaa tagatggatc ttcccacgac
     2641 aatggatgat gaaccaataa aatcgttccc ttttcagcag gtgtacccaa ccactcttgt
     2701 aattgaatca tctgtcctat cgatattttt ccttcgtgct gggtatcttg agcagaatcc
     2761 aaggaaataa ttcgtaaccc attttgattc gtacaatgga tatactctcc cgtttcattg
     2821 ctttcaacac tcattccttc aaagaaaaca ctgcgacgat catgattccc acgacaaaaa
     2881 tagtaaggtg tggttgggaa atattgatcc aacattttcc gtaagacttg ataatcagaa
     2941 atcccccctt catgtactaa atcacctgtt aatagaataa aatcgtacac tgttaacgag
     3001 agttcttgta acaatttttc caatgccaac tgtggatttt taattgttgg aaatagttca
     3061 gcagtaaaca agttagtttg atagttttct ctaaaatgga tatcagagag atgcaaaaag
     3121 cgcatggcta ttccctcttt cttcaataaa ataatcagga tatcctaaat tttcttgcgt
     3181 ctgataatca aaaaaatgca ttctttcagg ttctatgcgg agattgactg catcaccaat
     3241 ctgccaagta ggtttttcat taaggacaat catttctata ccatcgactt taacggtgta
     3301 cgcataactt tgacctaata gctcacgata cttcacttga ccgtgtaaat cgcttgtttc
     3361 ttttgaaaag gttacgtgtt ctggtcttat gcctaaatac aatgagccac taacctgaag
     3421 aagttgtttt tgccaagctg gattcaatgt taaaaattga ctggctacct ttaatgttcc
     3481 ttgatcataa gtaactggca taatattcat gcctggcgaa ccaataaaat ttgcagtaaa
     3541 agtattttta ggtttcgtat aaacattttt cggcgtatca atcatctgaa ttctaccttc
     3601 attcaataaa acaatccggt cagctaacgt catcgcttca atttgatcat gagtgacgta
     3661 gacaaaagtt tgtttataac gttgatgaat ttttaccaat tcttttcgtg catccaatcg
     3721 taaacgcaca tccaaatttg ataacggttc atctaataaa aaataattac tccgtttaac
     3781 caccgcacga gccaatgcta cacgctgccg ttgccctcct gacaaatctt taggaagtcg
     3841 atcttggtat ggcgttaaac ctaacatctt caaagcttct tccaaacggt gctgaatgtc
     3901 agctgtctta attttattcg cccttaatgc aaaaataata ttctccttta cagtcatgtg
     3961 aggatataaa gcataatttt gaaaaaccat tgcgatctct cgttctccac aaggtagctt
     4021 atttgctagt tgtgtaccta aaaaaagctc tccactcgta attttttcca aaccagcaat
     4081 cattctcagc aaagtagatt ttcctgaacc agatggtccc agtaacacaa ttcgttctcc
     4141 agcggccaca gctaaatcaa tttcttttaa aatggtatgt tctccatatt tttttccgat
     4201 atttcttaat tcaagcgttt ctcccatgat ttgtcctcca atttatttaa tacctgcaga
     4261 aacaaaagtc ccgataatat atttttgaaa aattgcatac aagactaacg gtacaaacat
     4321 tgtaattaaa ctaatcgcca ttgctacggt aaaatttgtc ccaccttcag aactaatata
     4381 ggtctgcatc gccaacggca aagtataatt atctactgtc cgtaaaatta ataccggcca
     4441 aacatactca ttccaagagg taataaaaaa ccaaataccg gtagaagtaa tcgcatgtct
     4501 agtaagagga aaaacaattt tactcatgac ggttgtttgt ttgatgttat ccaatgccgc
     4561 cacatctaga aggctcactg gaatttcccg cattgtttgc gtcaataaaa aaatgcccat
     4621 cgcatcagca aattgtggta ttatcacacc ccaagtagta tcaattaaat taagttttgc
     4681 aatcaacaaa taattaggaa tcatcgcaac agtaaaagga atgaacatcg taccaatgat
     4741 gataaagtac cagattttct tccctttgat tcggcaataa gtaaaactat atgccgcaaa
     4801 aaaagctacg cctaacttaa caaccgttat aattgtagca ataaaaaaag tatttctcgt
     4861 aattttgata attggaagat tttcgaacaa atagcaaaaa ttttccaagg taaacggctg
     4921 tggtatcaaa ctagtaatcg tctgataggc atctttcaat ggcttaaaag aattggccat
     4981 aataaacaat aatggataga taataatgat tatgatgaac ataaataaga gatgtggcaa
     5041 ccagcgttta attttcatag taaaccccct tttccacaaa tttaaatatt acccctaaga
     5101 aaacagcaaa tattaataaa gttaaaactg aaattgctga agattctccg actttataca
     5161 tttcaaaagc cttttgataa gcataataga tcacgtttgc actaccatta ttcggtccac
     5221 cacgagtgat gatcttaatc ggagtaaaca catactgcag accttgaaca atggtcatca
     5281 ccaataaata tagtcctgtc gaactactca taggcaacac aattgtaaaa aaaatgcgcc
     5341 agatgggtac acgatccaac ttagctgctt cgatcatctc ttgatcaatt cccacaattg
     5401 ctgcaaaaat gacaatgaaa ttataaccaa aaactttcca agcagtaata cctgcaatca
     5461 cagcaattac ccaaccttgt aaattcatcc acataggcag tcttaaacca aaatttccca
     5521 acaagacagc aattggtccc gataccggat ttaatatcca tgtaaaaacc atccccgcca
     5581 ctaccaaaga aatcacagct ggaataaaaa ataatggttt atacaaattc tgcccttttt
     5641 ctataactat tcctaataaa aaggatgtaa tatatgggaa cacacagctc agcaagacaa
     5701 atagaacggt ataggacaaa gtattcttca acactttatg aaagactgga tcagtcagca
     5761 cctttacata gttggcaaag ccaacaaatt ctttagtggg ggccaccata ttccagtcaa
     5821 aaaaactcaa atagatcgta taaatcaatg gataaaaaac aaacacgccc aacaaaataa
     5881 ttgctggcgc cagatacaaa taacctacat agcgcttcat ttccgacagc ctcctcatcc
     5941 ttatgtcaaa agcagacgac cttgtttttc ctttcttaca ggcgctgtcg tctgcttgct
     6001 ttgcttattt gagtaactca ttaatttcct tttgagtagc tttcatcgtt tcattgacgg
     6061 aattacctga taaaatttta tcccgcatat ccaacaattt ttgttcagct tctaatccag
     6121 catctccagg aaatgaactc caactgacca tcttatccat ctgatcaatt gctggtatca
     6181 tcatctgatt ttcagctaag aaagctttta atccattttg ggcgtctgca acatctttac
     6241 gtggtggtaa ataaccagta ccttctgtcc atttagctaa agattcaaca ctataaagat
     6301 attttaagaa atcccaagtt gcttcctttt tcttatccgt ttgtgatgta acagctaaca
     6361 ttgcgccacc agcaggtagt ttaacttttt tcccttccca acttggtgac tcaactgctt
     6421 tagcagtaaa agtactattt ttttgaatgt tgtccctttg agcaatagtg gtatagacca
     6481 tcgcgacgtt accatcaata aagctttgca caccttgttc ccacgtagtg tgtaatgccg
     6541 tctggtcttt taccatcctt tgatataatt cataagcagc gataccatct ttagaagcaa
     6601 aggtagcttt gccatctttt attacacttg ccccattact ttctaaaatt gcttgttgtg
     6661 cccaattatc agcaggttct tgaatataca cgccatactt tccagttttt tcttttatta
     6721 tcttagaaaa agtttgaact tcttcccaag tttttggacc attttcatcc aagcccgctg
     6781 cttttaatat atcttgattt aaatataaaa ccggattact aatggagtaa ggaataccca
     6841 cttgtttacc atctttttca gacagtgcca tgatattgtc taaaaaatga tctttaaaat
     6901 aatcagcatt atccggatcc acttcttcta ctaaagattg aggattagta tatttgaaat
     6961 tttctgcaaa ataatcttta aaagcccatc ccacttgtac tacgtccggt atttctttgg
     7021 aggcaacaga agcttgtaaa ttttgcatca agcctttata catatcagga ttatattttg
     7081 ctacaacctt cactttgtct tgagattgat tgtatttatc tactaattca ttcactgttt
     7141 ttccacctag ggtatccgca ttaacatgcc aatactctat cgttacacga ccctccgatt
     7201 tttttgttgt cttggtattc ccactaccac aagctgccaa agagatgaca cttaaaacag
     7261 acacaacccc tataacaaga tttttcttta acataacatt aacttcctcc taatttcttt
     7321 atggccattt ttctaatcaa gaaatattat gaactaccaa tgtaaatttc tagttaattt
     7381 tctgtaaata attcgaaatt tgtgcatttc ggggtacagg gtcactggac atatccatca
     7441 agctaagaat aaagccccca tatggtcatg tatcccatct ccaaatctct taactcctct
     7501 gttttgatta taaaatagtt tattctgtgc tcctttcttc cataaatagg cccatgcaca
     7561 acgtgaggtt atattataaa caccacagcg cgcaaggtac tcaatcgttt ctagttcatt
     7621 gactgtccat acagaaaatg tcaatcctag ctgctgcccc acttcacggg ccaacttagt
     7681 taaccatcct tcatgaatat tgacgatttg aacgctttga taggctaatt tctgtaaggt
     7741 atcgatcaaa tctgcttcgg taatatcccc aagttttttc ccttcgaact gattttcaat
     7801 attataaaat atatgctttc cccaaatcgc agcccaagat aattgtacat agccactaag
     7861 aacaatttgt ggccagattt gataggtttg tgccagcgaa aaaacggcca tttccaatcc
     7921 ctcttctttt aaatcacagt taatggtcat ggttgccttc tcattggcca ctgcttgaaa
     7981 cacctgctca agggttaccg aatctgggac aacttcttac ctgtcatggg ctagtattag
     8041 cgtaccatct gtttgctgac gcacatctac ttcaaaacaa agctggcgat ccaaacaaaa
     8101 gcgaagaaat gcccagctat tctcctccgt attgtcacta ccagagtgtg cagtgatcat
     8161 ggtcattttg acccctcctt taattccgtg attttctccc acacgtccac tataccgatg
     8221 aagcgttaat ttcttgttaa tttcttgtaa attccctgcg ttttttcagt aaactagttg
     8281 taaatcttgc atgctccttc ctacgaactc atgaatcgtc gattttgccc ttctagctag
     8341 tttcaccaat taagtagttc tacattcccc gcttttaacc tactacacct ttttttgttt
     8401 tcagctattc cttcttcttg ctgaaagtcc ttgaggttct ttcttacagg ataccatcaa
     8461 ggtgttcaat ggcttattcc cattgaatga ccgagactta ctatcagatt tctgctcgtt
     8521 gaaccaagtc tttgatacag gatttcttcc gtcatcttct cacaaatacc accttgcgtt
     8581 tctctagcga ttggtcgatg tgcaccctcc cagtggactg tcactacccc tttttgctat
     8641 gcctagccca caaaaaaagc tgtcctcaca gacagccaga ctgtagacaa aagctgttcc
     8701 aaactcgtaa ctcgagcttg gaacagcttt ttatctactt cgtttcgaat ttttgaacaa
     8761 aaaaataaag gctccttgcc tttccatagc caggtggcta atttctttaa attcattgca
     8821 gcaaacacta gcatcgtatg cgtcgcgact ttttccaagc ctcgatactt ggtccaacgc
     8881 atcccatgct tttcttttgc atccgcaaat attcgttcaa tcgtttgttt ccgttttttg
     8941 taaattgatt tattcagatc tgttaggcga agatgttcca cttcatccat cagatctccc
     9001 caaacatgtc tcgtgatgac tcgttgatga tttttactta tggtacattg gtttagcaga
     9061 ggacagttca cacattct
//
LOCUS       DACCVZ010000104         8973 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.107, whole genome shotgun sequence.
ACCESSION   DACCVZ010000104 DACCVZ010000000
VERSION     DACCVZ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8973
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.107"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            22..95
                     /locus_tag="IVW63_002517"
     tRNA            22..95
                     /locus_tag="IVW63_002517"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:56..58,aa:Ile,seq:cat)
     gene            complement(480..977)
                     /locus_tag="IVW63_002518"
     CDS             complement(480..977)
                     /locus_tag="IVW63_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP7860755.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(1017..1826)
                     /locus_tag="IVW63_002519"
     CDS             complement(1017..1826)
                     /locus_tag="IVW63_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7860756.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            2160..3017
                     /locus_tag="IVW63_002520"
     CDS             2160..3017
                     /locus_tag="IVW63_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAP7860757.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            3010..3912
                     /locus_tag="IVW63_002521"
     CDS             3010..3912
                     /locus_tag="IVW63_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAP7860758.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            3945..4295
                     /locus_tag="IVW63_002522"
     CDS             3945..4295
                     /locus_tag="IVW63_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP7860759.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            4329..5267
                     /locus_tag="IVW63_002523"
     CDS             4329..5267
                     /locus_tag="IVW63_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP7860760.1"
                     /translation="MRYYFVDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPD
                     DIFVGTEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLI
                     TCIDRKTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAAR
                     KTTENEELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQ
                     RQTEKMIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTG
                     GLPGKSSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            5345..6238
                     /locus_tag="IVW63_002524"
     CDS             5345..6238
                     /locus_tag="IVW63_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7860761.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            6276..6839
                     /gene="amaP"
                     /locus_tag="IVW63_002525"
     CDS             6276..6839
                     /gene="amaP"
                     /locus_tag="IVW63_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAP7860762.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            6853..7041
                     /locus_tag="IVW63_002526"
     CDS             6853..7041
                     /locus_tag="IVW63_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAP7860763.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            7054..7956
                     /locus_tag="IVW63_002527"
     CDS             7054..7956
                     /locus_tag="IVW63_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP7860764.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            7988..8230
                     /locus_tag="IVW63_002528"
     CDS             7988..8230
                     /locus_tag="IVW63_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP7860765.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(8486..8857)
                     /locus_tag="IVW63_002529"
     CDS             complement(8486..8857)
                     /locus_tag="IVW63_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860766.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         3121 a         1552 c         1741 g         2559 t
ORIGIN      
        1 aaaataaatt ttatttatga tgtaccttta gctcagttgg ttagagcaga cggctcataa
       61 ccgtccggtc gtaggttcga gtcctacaag gtacataaga ggttgtgaaa aagctgccct
      121 gcatcaagta ataagaacag ccaagtaaaa acagcttctt atgtttttac ttggctgttc
      181 ttattactgc agatgcaagc ttttgaatac cgtttaagga agaggttgtg aaatcagcgt
      241 tttgacctga gtattagctt aacaaacgga aaaatagttc ctcatatttt gccgtttgtt
      301 aagctaatac cgagggtcag ctgattgaac accatttaag aaagaggtcg tgagcctgcc
      361 gtttcactct gtgtcataaa aaagccaatc tactttgata gaaaaagcac gtaggactaa
      421 aacagttctg cgtgcttttt ttattgtgtg ttaaatatcg taaatgaaga tagatatttt
      481 tatgattcga cgatagagac gttgaaatct ttcaacagct ctaaagcgga ttctccgtgt
      541 tttctactgg agactaacat tggatcaaca aaaaagtctg cttcaggaaa agcactctgc
      601 aggcctatca gattagagag tacacacaag tttgtttcaa tcccgactac ttcgatctct
      661 ttttgttctt ctttgctttc aaataaagtt tcctggattt cagctaaagt ttcaggtgga
      721 atcgtaaagt aatacttttt aatcactcgt tcattttctt gtggagaaag aagagggatc
      781 aattgcaaat cttctcgttc ttcttctttg tccttcagtt caactggtat atcccgtgtg
      841 aagagaatat attcattatt ttggcgtgct ttagctaatc tttgagcaat acgttctgcc
      901 aattgatctg actctggaat ataaaattcg ctgtttggat caagaatatg attttgcata
      961 tcaataataa ctaacatttt ctttcctcct acattcatat cgtcatttta ttctttttaa
     1021 tagaagtttt ttaaaatata agcaacacca gcttcttcat tcgtcagtgt tacttggttt
     1081 gcaatttctt ttacttgtcg ctgtgcattc cccatcgcaa tactcaaccc gctgtaattc
     1141 aacatagcaa tgtcgttttc ttgatcgcca aaagccatga tgtcactcga ttcgattcca
     1201 aggtaatccg ccagaaaaac aagtgaatga gctttagtga tacctgtagg cgtgatttct
     1261 aagaaatgcg gatcagagaa tactgattgg ataccatctg cttgcagatc tctttgtagc
     1321 ttctgtagtt tttcttcact cttatctgtt aatgctaatt taagatagct aagagaagga
     1381 tcttccaaca tatttaaaat ttgatcaaaa gaatggttct gtaaattgaa atgttcataa
     1441 taagggtcat ctttgactag atttgattca tcgaatgtca gctgatcatc ttgggtttct
     1501 cggctagcaa tgatggatat tttcgcttct tgagcataga agaaggcttt tctcagtgta
     1561 tcgctatcta tttttgaacg tctgagaact ttcgccattt ttccatcctt catttcagca
     1621 atcagtgaac cattggaaga aatcaaatag ccaccgattc ctaattcgga aaaaatatct
     1681 ttagcagaaa tgctgttcct tccggtagcg acggttacga ttccgccatt ttcatcaaat
     1741 ttccgaagtg cttggatatt ttcttctggt atctttccat ttcgatcaag caaggtaccg
     1801 tctaaatcaa tcgctgctag tttcatttta tcttcctact ttctttttac atatctattt
     1861 tcctgttacc ttaagattaa atgagaattt aaaaaaatga aactaacttg ctttgtcatt
     1921 atgaattttt tcaaaaaaca ttcttaagaa aaaggtggct atatatagta gtttttggtc
     1981 aatacctttg aataaaaagc catgaaaaac gaatagttag cgcttaccga tgcgttttgt
     2041 gataaaaaaa ttttaaaata ttcaatgaaa acaaagcata tattttgctt taaaaccaaa
     2101 tgaggaatat tctagatgta gaacaggtta gaaaaagatt agaaaaagga gtgattttga
     2161 tggagaagag atacggcgta gttcctgtgg taactgcttc agacgaaaat tatgctcctt
     2221 acttgagcgt gatgatcgca actgcattag aaaattgcaa taaaacaaga cgcataaaat
     2281 tttatgtgat tgacgatggt ctatcagaat atagtaaaga aggattggaa gaaacggtaa
     2341 ataaatattc aagtaatgca agtatccaat tcctgacagt ggaaaaagat atctacgaag
     2401 acttcctagt cagtgaccat atcacaacta ccgcttactt aagaatttct ttaccaaact
     2461 tattagctaa agaggattat aagaaagtcc tttacttaga ttcagatgtg ttagtactag
     2521 acgatatcgt aaaactatat gatgagccgt taaatggaaa aacaatcggc gctattatcg
     2581 atccaggcca agtgaaagct ttggaaagat taggaatcga ttccgatgac ttgtacttca
     2641 attcaggagt gatggtgatt gacattgatc aatggaataa aaaagaaatt acagaaaaaa
     2701 ctatccatta cctcagtgaa aatggcgatc gaatcatcta tcacgaccaa gatgctttga
     2761 atgctgtact ttatgaagat tgggaacaac ttcatccaaa atggaacatg cagacttcgc
     2821 tgatttttga acgtcatcca gcaccaaatg aaaaatatga acgtcagtat aaagaaggaa
     2881 atgaaaaacc ttcgatcgtt cactttacag gacatgataa accttggaat acgttgaaag
     2941 atcatccgta taccaattta tacttaaaaa aattagcaca cagtactcta acgaaagtag
     3001 gcgagatcaa tgaataaaaa agaaatagca gtagtcgcaa gttgtaacac aaaattcgta
     3061 ccacatttag ctgcattatt tgtctcagta ttagataatt gcaacccgtc taaatttgtt
     3121 cggttctatg tgattgacga tgatatcgat tttgaaagta aacagctttt acgcttctca
     3181 gtgaaaaacg cacgaatgaa ctcagatgtg gaattcttga aaatcaataa agaattcttt
     3241 acaaatgtgg taatcagcga tcgtattcca gaaacagctt attatcgtat tgcgattccg
     3301 gaattgttcc gcggcacaga agttgaacgt atcttatata tggattgcga catgatcgct
     3361 ttacaagata tctctaaatt atggcgtctt gacttcggtg attcaatcgt agcagctgtt
     3421 gaagacgctg ggttccatca acgactggaa aaaatgaaaa tttcagctaa atcaatgcgt
     3481 tatttcaact caggtttgat gctgatcaat gtgaaaaaat ggttagatga aaatattacg
     3541 caaaaagtat tagatttcat cgaacataat ccagaaaaat tacgattcca tgaccaagat
     3601 gcattaaatg ctatcttaca tgaccgttgg ttaccacttc atccgcgttg gaatgcacaa
     3661 ggctatatca tggcaaaagc aaaaaaacat ccaacagcag caggtgaacg tgaatacgaa
     3721 gaaactcgca acaatcctta cattatccat ttttcaggac atgtgaaacc gtggagcaag
     3781 gattttgaag ggccaacgaa gaaatattac gaaaaatatg cagggatgac ggctttccgt
     3841 tgtgtagcta aattccctaa atatccaaaa tatgcaaaag ttcaaccaaa aacagatgta
     3901 gttgttaaat aatagaagac aacaactgaa gagggggagt aggaatggaa attacaatgt
     3961 ctaaaaatgc agtagagacg ttaattgaaa aggttgggga aaatacaaaa atcgcactcg
     4021 cgcttatcaa tgattccgat ccatttctaa gggacaaagg tgcttttgca aaaggcagct
     4081 tttttcaaat cattcctttt gtttcggaat ttggagaata tgcgactaaa atcgagcatc
     4141 cattattgga catctataca tctaaattag agcaaaatta tttcggtaaa cgattgaaca
     4201 tggacttcaa caaacagctt gacagctttt cattagaaaa tgaaatcgca gtactcgatt
     4261 ataatatcaa attaaagaac tgcttcttca gctaatagtt tcgagaaagt ccaaaaagga
     4321 ggtatacatt gagatactac tttgtggatg aagaaaagaa tgtaatagaa acagatgaaa
     4381 aaaaatataa ttggctcgta cttgatagtg caaagcccga agagattgag caagcaatcg
     4441 aagaattcga gcttcctgat gatattttcg taggaaccga atatccggaa gaagtttctc
     4501 ggatggagcg cctttatgag acgaaactag agcatccatt ttctttggta gtgattaatc
     4561 tagatcagtc agataatcgt atcgaaaaaa aattaacgcc aatatctttt gtactttccg
     4621 ataatctctt gattacttgt atcgatagaa aaaccgaatt tgtggatcgg ctgctgacaa
     4681 agcatggaaa tcatttaaac tcgtttgaaa agatcatcac gtatacatta ttagatattt
     4741 acacccatta cgtgaaagaa ctaagagaga tgaaaaagcg aattgacgct ttggataaag
     4801 cagctcgtaa aacaacggaa aatgaagaac tgtataaaca ggcagatctt gaaagagaca
     4861 tcgtatatat cgatcatacc ttaagagatc aacgggaaac aatggatcaa ttatggaatt
     4921 ctgaaacttt catcaaacgt ttagacgatg aacagctact ctatgatgtc catttgagac
     4981 agcgacaaac agaaaaaatg atcgagatct atcgagattt attagagagt attggtgatc
     5041 tattcaacgg gatgatggac aataatctaa atcatatcat gaaatatcta gattcagctg
     5101 cattaatcat ttccgttccg gcgttgttcg cagggatttg gggaatgaat acaggaggat
     5161 taccgggtaa aagttctgct ctaggcttta tactcgtagt ctttggctct ttgatagcag
     5221 cagtagtttt aggttaccat ttataccgga aagattatac aaattaaaga atctatttaa
     5281 aacaggtatc aaacaaagaa atttgttttg gcaatacaat ttaaaaacta ggaggaatac
     5341 agcaatgaca gaaccaaaat taatcgaccc gcgaaacttg taccatacgg agaaatttcc
     5401 taaacaagat caggatacac cagctttaca gcagaatatg attcctgttc ctgattgtgg
     5461 agaagaatcc tatgaaggca ataatcaact agaaaaccgc cgtgtactaa tcactggtgg
     5521 agattcaggg atcggtcgtg cagcagcgat tgcatttgct agagaagggg cagatatcgc
     5581 tcttcaattc ttcccaggag aagaaaaaga tgcagaggaa gtagcaaaat acgtgaaaga
     5641 tgcaggacgt aagattgtct tactaccttt tgatcttcgt gacgaacaag cacctaaaga
     5701 aatcatagat aaagccgtga gtgaacttgg cgggctagat acgatggtac taaacgcagg
     5761 acagcaaatt tcttgtcagt ctattgctga gttaccactt gagcaagtca aagacacatt
     5821 tatgataaac atcatcgcta tgtttgcttt agtgaaagaa gctgttccgc atatcccagc
     5881 aggaggagca atcgtaacaa caacttctgt tcaagcattc aatccaagcg aacatttatt
     5941 agattacgca gcaacaaaag cttcaatcgc taactttacg atcggtttag caaaacagct
     6001 tgcacctaaa ggaatccgtg taaatggtgt agcacctggt ccaatctgga caccattaca
     6061 actagacgaa ggacaacctt ctgattcgat ccctgaattt ggtcagcaaa gtttactaga
     6121 acgtgcaggt cagccaggag aattagcacc agtttatgtt ttcttagcat cgaataaagc
     6181 aagttatgtt acagcccaaa tttacggagt aactggtgga gaagcgatca acttataaga
     6241 agttgatcgt ttcaccccta tgaggaggtg cgaaaatgaa taaaggtgta aaaacgatcg
     6301 gagtgatcgg aacattactt ttgctatctg tgcttttgtt tgcgatacta ttaagtgcaa
     6361 cctatccatt gccttttcag ctagagaagt ttcgattctt ttccatcact aattcatacg
     6421 tgcaacaata tgtattttgg cttgccgttg catttgctat tttgacaatt atcacgttac
     6481 ttgttttcct gttttatcca aaaacaatcg gaaactttct actgaaacat ggtgatgggg
     6541 agttgacgtt ggataaaaaa gcaattgaag gaatggttcg ttctcacttg catgaagatg
     6601 aattcatcca ttcaccaaaa gtaaatgtca aagcaacgaa aaacaagatc gccgtcaatg
     6661 taaaagggga gttgaaacga acttcagcac tcattggtaa aacaggaaca ttgatgaaag
     6721 aaatcgaaaa tgaagtacaa cacatattgg gaacaaaaga gccagtgaaa gtatcggtga
     6781 aatacacagg ctttgaagaa ccagctaaac gaagcaatga ccgcaaacga gtagaatagg
     6841 gggggaccaa aaatgaaaga actattttcg acatacaagc tccctatcat ctttggggta
     6901 cttggattga tattagccgt tttatggatc accgtgggct ttttcaagac cttattgatc
     6961 ttgatcatgg cagcgatcgg cgtcgctatc ggtttttatc tgaaacaaac gaaaatctta
     7021 gatcactatt ttaaatctta ggaggaaaca tccatgaata acaataacaa aaataataac
     7081 aataaaatga acaaccaaaa accagtgtct gcacatccag acccaacgac accaaaccaa
     7141 tcaaatggtg tgaacgatga aaagaacaaa acagcaccag tatctgcaca tccagatcca
     7201 gtagtcccta acgttcaaca aggagtagaa gagaagaaac atgatgcaga aaagcatgca
     7261 cctcatcatc caggaactcc agaatctaaa gttccagaac aacatgatgc aatcgatcct
     7321 tctaaacctg tggaagagca aaaacatcct tctgaccatg cgaaagcaca agaaaaactt
     7381 agttctgacc acacaaacgg acaaggaaaa cttggttctg atcatacaaa taaccaagga
     7441 aagcatgatt ctgaacagga agattcaatg cgcggtgagc tgaattatga agataaagtt
     7501 gtgcaaaaaa tcatcggaat cgcaattgaa caagtagacg gtttattatc tgcaaacggt
     7561 ggtttcttct ctaatgtggc aggaaaactt gtgaatacag ataatgtaac ggctgggatc
     7621 gaaacagaag tcggtaaaaa acaagtagca gttgatatgg atgtcattgt ggaatatggc
     7681 aaagatatcg aaaaaatctt tgaagaaatg caagaagtaa tcggcaaaga agtaaaaaat
     7741 atgacacatt tagaagtgat cgaagtcaac gctaacgtag tggacatcaa aacaaaagaa
     7801 gaatttgaaa aagatcaaga aacggtgcaa gacaaagtaa ctgacgcagc gaaaaaaacc
     7861 ggtgaatttg cttcgaatca aacagataaa gtaaaatcag cagctggaag cggcgcacaa
     7921 aaagtaaaag aaaatacaga accacgggtt cagtaataag gaagtaaaac attaggagga
     7981 acgaaacatg ggatttattt ggtcacttat cgtcggagga attatcggag caattgcagg
     8041 agcaatcacg aataaaggtt cttcgatggg gattattgca aatgtcgtag caggtttagt
     8101 tggatcagca cttggtcaag cattattagg ttcttgggga ccaagtattg caggaatggc
     8161 aatcgtgcca tcattgattg gtgccatcat tttagtacta atcgtatcat tctttgctcg
     8221 aaaactgtaa aaagactttt aaaaagaggt cgtgaaaaag ctgttcttca tcaagtaata
     8281 agaacagcca aacaaaaata gcttctcata tttttcattt ggttgggcat attatcgaag
     8341 atgcaagctt ttgaacactg tttatacgga ataagaggct gtgacaagac ttttgtcaca
     8401 gcctcttatt tatgcgggca aattcccaat tagattttta aaagtttttc cttaaatgtg
     8461 tctttattga tacagagaag cttctttaat aaaacaatgc ctccctaaat tttcttgaga
     8521 taggaaaggt gaacatacaa aataatacga ccactttgaa aacccagatg atccacaaat
     8581 ggatcgtatg atactgatga agtaaaaagc aatggatcag aaactcaaag agattgaaaa
     8641 agacaaggaa gaaataatat ctctttttta ctcttgtctg ttttagccaa taatagctcg
     8701 taaagtaatc tagacaaaca aatagaagta aacaaagttt cgtaagagca gcaatcgtat
     8761 catgttgctc tgctagacga ttgacgagca ggaaaaatgt tggtaatgga atatagatca
     8821 cgagtaatga aagaaaaaag taaacaataa atggcatact attcctccta attgtgtgag
     8881 ttcgccctca ttttaaaata acgatatttg tttgtgaagc tttttcgtgt cgtaacaaat
     8941 gttatctaat gtatttttaa ataaataatc att
//
LOCUS       DACCVZ010000105         8952 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.108, whole genome shotgun sequence.
ACCESSION   DACCVZ010000105 DACCVZ010000000
VERSION     DACCVZ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.108"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            69..887
                     /gene="purR"
                     /locus_tag="IVW63_002530"
     CDS             69..887
                     /gene="purR"
                     /locus_tag="IVW63_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAP7860767.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            1390..2763
                     /gene="glmU"
                     /locus_tag="IVW63_002531"
     CDS             1390..2763
                     /gene="glmU"
                     /locus_tag="IVW63_002531"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAP7860768.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            2857..3828
                     /locus_tag="IVW63_002532"
     CDS             2857..3828
                     /locus_tag="IVW63_002532"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAP7860769.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     regulatory      3834..3936
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4002..4571
                     /gene="thiT"
                     /locus_tag="IVW63_002533"
     CDS             4002..4571
                     /gene="thiT"
                     /locus_tag="IVW63_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HAP7860770.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     gene            complement(4652..5425)
                     /locus_tag="IVW63_002534"
     CDS             complement(4652..5425)
                     /locus_tag="IVW63_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860771.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            5692..7392
                     /locus_tag="IVW63_002535"
     CDS             5692..7392
                     /locus_tag="IVW63_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HAP7860772.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            7362..7580
                     /locus_tag="IVW63_002536"
     CDS             7362..7580
                     /locus_tag="IVW63_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860773.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            7600..8490
                     /locus_tag="IVW63_002537"
     CDS             7600..8490
                     /locus_tag="IVW63_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAP7860774.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            8508..8792
                     /locus_tag="IVW63_002538"
     CDS             8508..8792
                     /locus_tag="IVW63_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860775.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
BASE COUNT         3020 a         1532 c         1887 g         2513 t
ORIGIN      
        1 gctcgaattt ttgaagaaaa acttatataa tgtaaaacga taaaatttct taaaaggagt
       61 tggaataggt gaaagtacgt cgcagtgaac gtctagttga catgacacag tatttattga
      121 atcacccgca tgaattgatt tccttaacaa gctttgccga acgttatgaa tctgctaaat
      181 cttctatcag tgaagatttg ggaatcatca agaaaacatt taaagaacga gggtatggaa
      241 ccttggaaac aatcccgggt gctgcaggtg gtgtattgtt catccctgaa atttcatatg
      301 aagaggcgaa aaaatatatt gaatctctag cagaacgtct atcagaacaa gaccgtctgc
      361 ttccaggagg atatgtttat ctctctgatt tgttaggaga acctgaactg ctgcgtcaag
      421 ttggaagaat cattgcttct aaataccttg gtgaaaaaat cgatgctgta atgactgtag
      481 ccacaaaagg cgtacctatt gcccaagctg tgtcctatta tctgaatgcg ccattcgtta
      541 ttgtacgccg ggactcaaaa ataacagaag gatcaacagt aagtgtcaac tatgtgtctg
      601 gatcttctga aagaattgaa aagatggaac tgtctaagag aagtttgaaa cgtggttcac
      661 gtgtccttgt agtggatgat ttcatgaaag gcggcggaac agtcaacgga atgaagagct
      721 tgattgaaga attcgaatca gaacttgttg gcatcactgt atttgccgaa tcaaaattca
      781 acggtcatcg cgccatcgat gattatacgt cactgcttta tgtcaaagat gtagatactc
      841 aaacgaaaaa tattacggtt gtgccaggaa attatttttc agaataagag gttgtgaaaa
      901 agctgcttag tttcgagtag taagaaaaat tttgtgaaaa tggctttcca cattttttca
      961 taaatttggc ttaataccga gaaactggct tttgaacacc gtttatctag aggttgtgaa
     1021 atcagcgtcc tgtcctgagt attagctcaa taaacggaaa aattgctcct catattttgc
     1081 cgtttattga gctaataccg aaggtcagct gattgaaaaa cgtttaatga agaggttgta
     1141 agcctaccgt ttaactctaa gtcacaagaa acgatttcaa aaaacagctt ttcatgtttt
     1201 atgagtagtg tgacttgtga ccgaggagtt ggcaggagag caccggttac caaatagata
     1261 ggcccgttat ggtctatcta tttttttatc cagaaaacgc tgggataaaa gaaaatcact
     1321 tgttttgttg aaaaaatggg tatactggga taaactgaaa tcagcaaact atatttagga
     1381 gtgacgcagt tggacgcacg ttatgcaatt attttggcgg cagggaaagg tacccgcatg
     1441 aagtcaaaat tatataaagt tttacatccc gtttctggta aacctatggt agaacatatc
     1501 attaatcggg tcagtgaaac gaaaccagat gaagtgatta cgatcgttgg acacggagca
     1561 gaacaagtta aagcacaact aggagaacgc agtaaatatg cgttacaagc agaacaattg
     1621 ggaacaggac atgctgtttt gcaagctgct tctttcttgg aaggaaaaaa aggaacaacg
     1681 ttagttatca gtggcgatac accattattg actactgaaa cgctgaacaa tctttttgaa
     1741 tatcaccaag gaaaaaatgc aagtgcaacg atcttgacgg cacaagcaga aaacccaaca
     1801 ggatatggac gaatcatccg tgaccatatt gggatcgtag aaaaaatcgt ggaacaaaaa
     1861 gatgcaacac cagaagaagc tcttgtacaa gaaatcaata caggaactta ctgttttgac
     1921 aacgaagctt tgttcgatgc gttaagcaaa gttggaacaa acaatgctca aggtgaatac
     1981 tatctaacag atatcatcga aatcttaaaa gaagaaggcc atacagttgc tgcttatcaa
     2041 acggatgatt ttgaagaatc aatgggagtc aatgatcgga tcgcgttagc taaagcaaat
     2101 gagatcatga gaaagcgaat taaccagatg catatggtca atggcgtaag ctttgtcgat
     2161 tcagcaacga catacatcga tgcaggcgta gaaatcggtc cagacacatt gatcgaagca
     2221 ggtgtacaaa tccaaggaaa tacagtcatt ggttctgatt gtgtcatcgg gtcacattca
     2281 aaaatcgtag acagtaggat tgaggatcac gtcgtcattg aaaactcagt cattgaaagc
     2341 agccatgtca agaaacatgc agatgtggga ccttatgcac atttacgacc aaaagctgaa
     2401 attggcgaaa acgtccatat cggaaacttt gtggaagtga aaaatgctca aatcggcaaa
     2461 ggaactaaag tcggtcactt gacttatgtt ggtgatgcta cgctgggaga agaaatcaat
     2521 gtcggatgtg gtgttgtctt cgtcaactat gatggaaaga acaaacatca tacgactgtc
     2581 ggcgaccaca gctttattgg ttctagcacg aatatcatcg gacctgtcga ggtagctaaa
     2641 aacagttcga ttgctgccgg gtcaacaatt acagacaata ttccagaata tgcgctggca
     2701 attgcgagag caagacaagt caataaagaa ggatatgcaa aaaaactccc ttatctaaac
     2761 taagactttt gcaaaatcac ttgatttatt taaaaaatat gactactatt tattaggtag
     2821 aattctagag ttgtgaaaaa gaaagtggag gtccccatgt caaaacatta ctttgaccca
     2881 agattaaaaa tttttgcgtt aaattccaat cgcccattag cagagaaaat tgcagcagca
     2941 gtcggcgtcg agttaggaaa atcatctgtt actcaattta gtgatggaga aattcaagta
     3001 aacattgaag aaagtattcg tggatcgcat gtctatgtta ttcaatcaac gagcagccca
     3061 gtcaatgata acttgatgga gttgctgatc atgattgacg cactgaaacg agcaagtgca
     3121 aaaacaatca acgtagtcat gccttattat ggctatgcgc gtcaagaccg taaagcacgt
     3181 gcacgggaac caatcacagc gaaattagta gcaaacatga ttcaaaaagc tggtgcaaca
     3241 agaatgctga ctttggacct tcatgcagtt caaatccaag gtttctttga tattccagtc
     3301 gatcatttga tgggtgcgcc acttattgcc aattatttct tagaaaaagg aatcaaaggc
     3361 gatgatgttg tcgttgtttc accagaccat ggtggtgtca cacgggcacg taaattagcg
     3421 gaatttttga aatctccgat tgcgatcata gacaaacgcc gtccaaaagc aaatgttgca
     3481 gaagtaatga atatcattgg acaagtcaaa ggcaaaactt gtgtactgat cgatgatatg
     3541 atcgatacag caggtacgat cacattggct gccaatgctt tgaaagaagc tggtgcaact
     3601 agtgtgtatg cttcatgtac acatccagta ttatccggcc ctgctttaca aagaatagaa
     3661 gattcagcta tcgagcgtct agttgttaca gactcgatct atcttccaga agatcgtaaa
     3721 atcgacaaaa tcgatgaagt aagtgttggc ggactaatgg gagatgcaat caaacgtatc
     3781 catgaaaaca aaccagttag tccattgttt gaaacaaaaa ataaataata aataaactca
     3841 caaaggggag tccaattggg ctgagattga atctatttct aaacccttcg tacctgtatc
     3901 ggttatgcga gcgtaggaat tgtgaataaa cagctgtttg actattttcg aaagctgctt
     3961 cctcctttgt gactttttta ttcaaaggag gaagtttttt tatgggaaaa aatagagttt
     4021 gggtagaagg aacgattgtt gcagcgttag cgatggtgtt gtcgttgatt ccgatccaga
     4081 tcggcagcag tttttctatt tcattagggc agattccatt gactcttttt gcgttaagaa
     4141 gagggacaaa ggcagggatg ctggcaggtt tcatttgggg catcctacat tttccgttgg
     4201 gacaagttta ttatttaagt gtcgttcaag tgttgattga gtacccgatt gcctatactt
     4261 ttgcaggcgc agcagggctc atggcttcaa atgtccaaaa aggctatgta gacgataata
     4321 cgaaacaaat tagaaaaagc atcgtgtttg gtgcattgat tggcgcactt tccagatatt
     4381 tttggcattt tattgcagga gtggttttct ggggagcgta tgcactatgg gggatgaatc
     4441 cttggctctt ttctttcgta atgaatggtg ccagcgggtt gagtacagct attgtaacga
     4501 tcatcgtttt attagggatc caacaaacga ctccttcgat ttttgtgcca gataaacgac
     4561 aggagctgta aataaaaaag aagcaagaaa cttgagacag aatcatgtcc tagtttcttg
     4621 tttccttttt attttttgat aagaaataga tctacttcaa tggcagataa gaaagatcgg
     4681 catcttctac caattgccag tgtcgatcgg tgacagagta gattaaagta gcgatgattt
     4741 cctcttctcg ataccgggtg ccttttaatt tccaaatata atcttcaatc acatagattg
     4801 ggatacgata tttaccatcg atcaaaccaa cttgatcaaa agaaaaaatg atcccttcct
     4861 gcatcaaatt acgcatttct ttcaataatt ccacactgat tttttcaaca ggtgtttctt
     4921 ttttgaaaaa agattttttt acattgatct tatctgacaa gatcgaactt aatttactag
     4981 caaaaatcct ataaaattca tctaaatagc gataataaat ccgattcagc tgatcattaa
     5041 gatcgaagta tacaaaatta ttctgtagtt tataaaaaaa cggcgaatga agatgtgttt
     5101 tcatatgacc aaaatataat aattctgaaa tttctaaagg tgtcaattct ttcagcatcg
     5161 ttaaatcagt aaagtcgatc cacttcaatt catcgaatcc acgcctgtta cgagaagagg
     5221 aaaagaaacg ctgaatattt tctgtaccac ggattacttt cagccctgta tgggattcat
     5281 attctccagc agaagcagat ggatcaagca agagcaagtt ttgaggaaaa tgcacgatac
     5341 tgtttgcaaa gtcagtagca gtcagccctt ttgttaaaac agcattactt gtggtatcaa
     5401 tatgtacata aactgactca gtcatcatgt tcctcctctt atttcctctt aatctctttt
     5461 attttacaac atttgcatta aaaaagcttg tttcttttat tttaaaattc cattacaaaa
     5521 tcacgttttc attgaaaaca ctctcatttt caattaattt ttgtgatttt tgtatttttt
     5581 tatttaaagg aggttttatg aattgttttc ttatggaatc tacaaagtcg aatacgagac
     5641 tcatgacctt tttatgacgt actggtatac ttgaagaaaa aggagagcgc gatggagata
     5701 aaaaaagttt acttttcaca gaaaatgtcg ctgtattcgc ctatccagca agcaaaacaa
     5761 ccccttccat tttttcaaag tcatcaagaa agtagagacg ctttttggcg ttctgcaaaa
     5821 aagcaatgtg cttttaaagc agtatcgaaa aaatataccg tctattttac tattgctaaa
     5881 agtagaggag atgttatttt taataatctg ttgattgaag gtgaaacttt tgaatggaaa
     5941 aaattttttc ggtatatgga agcttgcgct cgttttttta ttaaagaaaa ctgttgtttt
     6001 ttatttcaat ctcctctatc agaagaatgg ttgcgtattt ttcataaaaa cggctatcaa
     6061 ggaaccacac aattaaataa aaagctggtc tatcatacag cacttgtttt aggtggagga
     6121 ggagcgcacg gtgcttatca gattggtgtg tggcaggcgc tgaaggaaca tgatatcaac
     6181 tttgagatta tcacaggtac ctcggtaggt gcgttgaacg gcgcattgat tttacaagga
     6241 gatatgaaaa aagctgtgaa tttatggaaa aagctgtcga caagacaagt gcttgcgtta
     6301 ccagaaatgg ctgcagttga agaccttcgt gaacgcttct atcgagaaag acgccaaatg
     6361 acgaaaacag cactaattga aggcggggtt tcttctgctc cattggaaaa gatggtcaaa
     6421 gacaatttgg atttgtcctt actcaaacat aatcccaaaa tacgtttata tacggtgtct
     6481 actaaactgc cagaactagc ggaagtagtg actgatatcc aacagacaaa aacagaagaa
     6541 ataccagatt ggatactcgc ctctgcttca ttttatcccg ctatggctta tcgaaagatc
     6601 ggaaaaaata aatatgcaga cggtgggtat cgcaacaaaa tacctattga tattgcgatt
     6661 aacaaaggag caacagaggc atttgtcgta gatgtgcaag ggccaggccc agcgaaaaaa
     6721 attcgtatgc cagacatttt tatccattgg aaatgtcaaa cattgtggac actaggcagc
     6781 tttctgcttt ttgatagcca aaggaaccaa ttaaatttac aattaggcta tctggaaatg
     6841 aaaaaacgat taggctatta ctatgggaac tggtatacat ttcattctgt taaacctgca
     6901 agaacatact ggcgaggatt tttgtcttac ttaacaaaag aaattcagtt agaattatct
     6961 tttttcaaaa gcataaaatt ttggcaaaaa ctgcgtaatt tatataagaa cagggtcgta
     7021 ccagagacat gcggattggc gatgctagaa cttttagcaa aaaaacattt tttactgccc
     7081 aatgaaatct atcaagtaga catgatgatt caaatgatct gccaacaaga tataaaaagt
     7141 atgccggatg atttattggc acaaattggt caattaagta ctgaagaatg gcgaaggtat
     7201 cgaaaatacc agcaaaaaat acaaaatgag cgcacgaaaa ctgtttattt tgattatctg
     7261 ctacaaggaa aacgcaagga tcgtttgcag catgaattgc ttaagcaacc agttgacaca
     7321 ttactgatcc tatatttata ttatctcaag gaggaacaac catggcacaa gaattttcat
     7381 atgaaatcgt agaagaaatc gctatattgt cagaaaacaa caaggggtgg cgtaaagaac
     7441 tgaacctagt cagctggaat ggtcgcccgc caaaattcga tcttcgagat tgggcgccag
     7501 accatgaaaa aatggggaaa ggcctgacat tgacgaacga agagtttgaa caactgcaaa
     7561 aagcaataga aaatatgtaa tgaggaagga ccctgtcgaa tgaaaagtat gactggtttt
     7621 ggcaaagcca tccgcgaaac aaaagcgtat cagttagata ttgaaataaa aagtgtcaac
     7681 cagcgttttc tagatgttca aatacgaagt cctaaaatcc tgaactttgt tgaaaacgat
     7741 tttcgtcagc ttattaaaca gcagttaagc cgcggtcgaa tcgaagtatt tgtgaatcta
     7801 gcttatattg gcaaaaacga aaaacagatc gtcatcaact gggaattgat tgattcactt
     7861 atcactcaat tgacagacgg aattcaacaa cgatacggta gtcaaaatca agtgtcaatt
     7921 agtcggatgg cggaacgctt cgcgctggac gaaaacttcg taacggtaga agaaaaaccg
     7981 gaagagagca tggaagaatt ggcacagtta gctctagata cattgaaaag cgcacttgat
     8041 tctattgagg cgagtcgaga aaaagaaggt caagctttag ctttagtgtt gaaaaagaat
     8101 actgaagaat tcaaagaagt actaaaaaaa ctcgatagtt ttgtagaaat ctatgaaaag
     8161 gaatttcaaa taaggtatca aaaaaagctg gaggaatttc ttggagcgaa agtcgatgag
     8221 caacggttgt tgacggagct agccatcttg ttggaacgcg gagatattca cgaggaactg
     8281 gatcgtctgg cgatccatgt acaaaaacta gatgaactta tcgaagcaca atgtcctgta
     8341 ggtcgggaat tagatttcct gatccaagaa atgaatcggg aaatcaacac gatcggttcc
     8401 aaatcaaatg caatcgaaat taaaaatcaa gtcgtccagt ctaagacgat cttagaaaaa
     8461 atcagagaac aagtacaaaa tattgaatga cgaaagaggt agagataatg aaatattatg
     8521 acgtaacgtt ccacgaatta agtggaaaaa ctgtggttaa acgggatatc ccttctgaaa
     8581 aaaacggctt tgacgtatgg aaagatgcct gtgcagacta taatgagaac gaactgttta
     8641 ttttgatcaa cgacggtgct tacgtgacga tgaatcggaa atttattgtt cgaattgaca
     8701 cagaagaggt agaagatccg acagaaaaag cacgttctcg aaaagatgag atcatgggtg
     8761 tagtgaatac tttgtccaat atgggctttt agcaaggatg ctgaacaaag aaatacaata
     8821 aataatcaga attggatttc ttcgcttagc ttctttgctc taggaataca tttaaaggtt
     8881 gtgacaaaat tcgtgtcaca atcttttttt attttgaata agtgatgttc aaaaaccatt
     8941 ttctcggtat ta
//
LOCUS       DACCVZ010000106         8815 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.109, whole genome shotgun sequence.
ACCESSION   DACCVZ010000106 DACCVZ010000000
VERSION     DACCVZ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.109"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(135..425)
                     /locus_tag="IVW63_002539"
     CDS             complement(135..425)
                     /locus_tag="IVW63_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860776.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(543..803)
                     /locus_tag="IVW63_002540"
     CDS             complement(543..803)
                     /locus_tag="IVW63_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860777.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(940..1353)
                     /locus_tag="IVW63_002541"
     CDS             complement(940..1353)
                     /locus_tag="IVW63_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HAP7860778.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1809..2294)
                     /locus_tag="IVW63_002542"
     CDS             complement(1809..2294)
                     /locus_tag="IVW63_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860779.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2433..2648)
                     /locus_tag="IVW63_002543"
     CDS             complement(2433..2648)
                     /locus_tag="IVW63_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HAP7860780.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2872..3672
                     /locus_tag="IVW63_002544"
     CDS             2872..3672
                     /locus_tag="IVW63_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7860781.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3691..5559
                     /locus_tag="IVW63_002545"
     CDS             3691..5559
                     /locus_tag="IVW63_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP7860782.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5552..6043
                     /locus_tag="IVW63_002546"
     CDS             5552..6043
                     /locus_tag="IVW63_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HAP7860783.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6031..6585
                     /gene="srlA"
                     /locus_tag="IVW63_002547"
     CDS             6031..6585
                     /gene="srlA"
                     /locus_tag="IVW63_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174078.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAP7860784.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6603..7598
                     /locus_tag="IVW63_002548"
     CDS             6603..7598
                     /locus_tag="IVW63_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAP7860785.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
     gene            complement(7740..>8815)
                     /locus_tag="IVW63_002549"
     CDS             complement(7740..>8815)
                     /locus_tag="IVW63_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP7860786.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT         3046 a         1425 c         1683 g         2661 t
ORIGIN      
        1 gttactatga ataacataat aagaaagtaa agtggattga tttgagatct ttttatactt
       61 caaaaaagat aacacccaac tttcaaaaat atgttttgga agttgggaca aacgagttaa
      121 tacattttaa tacattattt tttattcaaa aaaaatagca caatggcaaa gatcgtaaga
      181 gagatcataa gccccaatga atgactaaaa agaaaagcag aatcacatgc catatcatcc
      241 catatttctt caagaaaata aataagcggg aaaaagggaa ggaatagtag aacatcgatc
      301 cagcaccatt tttttcttct tttgaaataa cataaaacaa taaacatgaa cgtgcaggga
      361 agtaaaaaca aagctttact cataactaac aaaataccag ctccttttat ttttttctcc
      421 cccacattca aagagtaaca atggtatgta cttaataata gaaaaatgga tcaacttgta
      481 tgaataacag ctgaaaagat ctgcaccaaa taaaaaactt ccagccaaaa ctgactggaa
      541 gtttattttt ttctgaaata ttctaacaca aatatgaaaa agatggccga agctaataag
      601 ccgatttcgt agcaaaacaa tgagatacca gagtcgtaat aataaaatcc tctaatctta
      661 tggataaaat agatcatcgg acaagcagat aagagtaagt atttgttagg ccttttgaat
      721 aagtaaaaga aagcactggt cattatgata aatggtatcc aaaacaaaag tttacttaag
      781 acaatcaaat gatcaactcc catatttttt accaagagag atcataacat ctttatcgta
      841 aaaacaaaat atttttttgc tcattttgaa aatttaaaca tactcgttct tatccaaata
      901 tataaaaatc gcccctcatt catcgagagg cgataagttc taatttaact caattttttt
      961 tgtttctttt ggctgataag ctgttttagg taataccaat ttcagcacac cgtttttaaa
     1021 ggttccagtg attttttctt catcaacatt aggaagatag aatgaacgtt tgtaagagac
     1081 cgaatgtctt tctttccgta catagttgcc atcttcttta tcttctgtat gggactcatg
     1141 attggcggag atcgtcaaag tattatctga atattcaact gtcgtgtctt ctttgtcaca
     1201 gccaggcata tcagcagtta gtttgtattc tttttcattt tcgactaaat ctacttttgg
     1261 ataacttgaa acacctaaaa aatcattgaa tgctggacta aacacgtcat tgaaatcagg
     1321 gaacatgtcg cgaatgctag gtacatttgc catttttgat catcctttca ataagtattt
     1381 tttatttatc cctatttacg taataactct attttgaaaa aaatgcaagt ataatggtta
     1441 gctttgtgaa tatttcatct aatacgatac aaaggctatc tttctaattt gaaaaaggga
     1501 tcattaaaat aataagaaga aaatatgtca aaaggtaaaa aagtaaattc ttctatccaa
     1561 atatagaaaa attgaatcta gaaaaccgcc cgacaataaa tttcattaac tcagttgacc
     1621 gaaaatgaag tagataccaa aaatttatca agagagcaag tagagaagtg agtatattca
     1681 taagagaaat agctgtaacg aattattagg ttaatgcaaa tgcttattta tactccgtat
     1741 aactttctca gaaaaaatga taccaataat gacttgctag tactgtaaat ccgtataata
     1801 tcatctaatc aaaatggtgt tccatttgca tctgtcatcg taatcgatcc ttcgggtgac
     1861 actcgataaa aaccaacgct tccagatcct ccttgggaac ggatttgttt gctggaagct
     1921 gtgaacaaat aatctcgatc aattttttga taaaagctaa taacaatatc gtcactttgt
     1981 aattcggaac ggtgggcaat aagaaataga agtgctttgt cagagttttc taatggaaga
     2041 gaaggtacag tgctttcttg catttcagat gttgaagaaa tgctaaacga ctgaatactt
     2101 gattggctat gttgcgaatc tacattacca gtagaagtat tagtaatgga agtagtagaa
     2161 gtacttttag ttgaaccaac ctcagttgtt gaaatggctg ctgaagattc tttaacagaa
     2221 ttctttgttt tatatccaca ggcagaaaaa agtattacag ttcccaacaa gcctgcgtaa
     2281 atccctttat gcatgatagc tcctcctaaa atagattatc tttattcagt atatcactta
     2341 aacaaagaaa agcagatggt ttaaaatgaa aaaaccttcc caataaaggg aaggttcatg
     2401 aagataataa cttttttaat aattatagct ttctaatatc tttcatcaac ttttctagta
     2461 atcattggga aaaatttcaa gcagtagatc gcacaaatac ctacgacgat ataaatgatc
     2521 ttcgcaaaaa tagttgttga accaccagca atcatagcta ctaaatcaag ttcgaacaag
     2581 cctaccaaca gccagttcaa ccctcccaca atcaataaag ttaatgcaat agcatctaaa
     2641 gttttcatta gaattctcct ttcttaaatg ataaaacaat tatatatcaa aaagagaaac
     2701 attgcttata taacgctcag gaattttagc aatctatgca aaaagatgaa aatttttttt
     2761 gctcttccat tagtacacat tttttagctg aagctgtaaa tttcatgtct taattttttt
     2821 tagtgagctt ttatactgga tttgtaagaa aaaagaagga gaggatcaca tatgtcggat
     2881 tggttggata ttgcaggaaa agtagtaatt gtaactggag gttcctcagg aattggaaga
     2941 agtatcgtcg aaaatttgtt gaagcagaat gcacaagtag cgaattttga tgtaactgaa
     3001 tgccgtatac agcatgaaaa cctactatct ttaaaagtcg atgtgtcttc taaaacggac
     3061 atagaagaag ggatatataa agtaatgaaa catttcaaga cgatcgatgg tctagtcaat
     3121 aatgcaggaa taaatattcc ttctcttcta atagatagaa atcatccaaa aagcaagtat
     3181 gaattatcag aacaagtttt tgataagatg atcgctgtca atcaaaaaag tgtatatttg
     3241 atgagccaag cagttggaag aatcttggtg caaaagggat caggagtgat cgtgaatctt
     3301 tcttctgaat caggattgga aggatcagaa ggacagagct gttatgctgc tacaaaagca
     3361 gcgatgaaca gttttactcg ttcttgggca aaagagttag gaaagaggaa tgttcgtgtg
     3421 gtaggtgttg caccagggat actggaagaa accggtttga gaacacaaga atatgaagaa
     3481 gctctttctt atacgagagg tataagcgtc gaacagctga gaaacggtta cagtcgaaca
     3541 agtacgatcc ctctaggaag gagtggtaag ctgcaagaag tggcggatct agtctgctat
     3601 tatctttcag aaagatcaag ttatatcact ggagtcacga ctaatatttc aggaggtaaa
     3661 acaagaggat aaaggatagg ggggacgcac gtgacgctag taaacagatg gtaccaatta
     3721 ttgaaattac tagtcactca caagaaagtt tcaatccagg aagtgcaaaa agaaatcaaa
     3781 accagtaatc aaaccataaa aaaagatatt ggggagttga atgaagaaat tgccggtatt
     3841 gcaaaaatca tccaaaaaaa caaacatttt gaacttgaaa tttatgattt tgattttttt
     3901 gatgagatca tgcaaggaaa attgaaaaca gccagtgatt tcaattcggc atccaaaaga
     3961 atcgcttatt tactaaatag gctgatcgaa acagaggatt tcttacgtat ggatgatttg
     4021 tctgaagaag tcggtgtcag cagaggaaca gtggtcaagg atctaaagac attaaaagag
     4081 atgatcaatg attttgatgt aaagattaca ggcacaccaa ataaaggact aagaataata
     4141 ggagatgagc tagaattacg actactttta ttttattttg tttctcccta cttttcagag
     4201 acgaaaacag aacagtttct agaagaaaaa caagcaatca aacattttca gaagaagacg
     4261 aatgctagta aacaagaaat caccctttta acgaaagtta tcggtatttc tttgaataga
     4321 atctctagta actatctgtt gaagaagccc atcaatcgtt acagtgggtg ttttgaatat
     4381 atccaagaat tcaatgaact gatcaatcag ttggaagaaa tctatgaact aactttgagc
     4441 caatatgaaa aagattttat cagttttcct ttgaacatca tcaacacaag tataacgatg
     4501 ataaggaaag ctaactctga tttgcgctta tatttcgacc ccatgatgat gcgtattcga
     4561 cgattagatc tcattgatct ggatgagtcc ttcttatatc aagagatgaa acagcacctc
     4621 tctttattga taaatcgggt aatttttcgt tatcgattga ctgatttatt ttatggtgag
     4681 atagaaaaaa agtatccttt ttcttaccaa atcgctagcg aatgcataca agcattagaa
     4741 gctatcttgc aacataagat ctctaaagta gagatcagct acctaacgtt gtatttggag
     4801 ttagcatttc gatatcaaaa agagcatttt tcctctaaaa aagtagccat tgttcatacg
     4861 acaggaaaag gaacagcatt aatgatccaa agacaaatca aaaggatatt ggggagggat
     4921 atacaaataa cacatgtttc agaagaacaa tatgaaaaag tagatctaaa caaatatttc
     4981 gctgttttta caacgattcc gttaaaaaat gtaaatgaag agacaccggt gatccatttg
     5041 actaatcttt ttgatgactc ttggttaagg gcacaatggc aaaaagcaaa aaaaaagcga
     5101 ttagccgggt ttcattctac tgtttttttc tatcaaatat ggaaagaaaa aaagacgtat
     5161 caagaatatt taaacaaatt agtcgctcct ttgatcagag gctattatgt ggatgaagaa
     5221 tttgaaaaaa ggatcttgaa aagagaatat cagcaaagca catttgttaa caaagaattt
     5281 gcttttcctc acacaaccaa ccagctatct caacacattg ttttatcagt agggctaata
     5341 actgatcaag gtttagcaga aacaggagga aatggagtta tttttttatt tgccatacct
     5401 gaagaaatga cggctgaagt tgagaatgaa ttatttgagc tatacgatat cctatttgaa
     5461 ctcataaaaa tgggaataga tgagtttatt gaattagcac cgacacaaga atcattttta
     5521 aaactaatca aaagtaaagg agagagactt catgaatgat atgtatctat tcatagtttt
     5581 cgcagcttca gcttatgtgc tgcaagcagt tatcagttgg aagcaactaa agcatttcaa
     5641 tcaaacatat agcgaactgc gaagaaaagg aaaagtagcg attggtaaac gacctgggaa
     5701 aatccgttca ggcacgattg ttatgctagc tatagacgat catgatcaag ttttagaagt
     5761 cagaaaaatg caaggggtta catctttggc aaaatttcat tcattacctg tctatgcggg
     5821 tgaagatatc cattacatcg atcgttacca tccctcagtt cgagcggaag atcgtttgac
     5881 acaagcagct ttagaaaatg ccagagaagt atacttacga atagaggcag gaaatgaaaa
     5941 aagtgaacaa ccttcattgc cttttattgc tatgctcaat aattttcgga tatggaaaag
     6001 tacgatcaaa gaaaaaagga gtgacaaacg atggatatca taacaaaatt tgctgaggga
     6061 tttatgaggc tgttccaaac aggtgcagaa acattcataa gctggatgac aggaatcgta
     6121 ccagttgtct tgatgctgat ggttgcaatg aatacgctga ttgctttttt aggtgaagac
     6181 cgagtaacga aagtagccaa attatcagcg aaaaatccgc ttactcgtta ccttgtgtta
     6241 ccgttcttat ctgcttttat gttgggaaat cctatgtcat ttacaatggc tcgtttcctt
     6301 ccagaatact acaaaccaag ctattatgct gctcaagctc aattttgtca tacgagcaat
     6361 ggtgtattcc cccatattaa tcctggagaa ttgtttgtat ggatggggat tgctcaaggg
     6421 atcgaaacct tagggctaaa ttcgatggag ctggctatcc gatacttgct tgtgggactg
     6481 ctgatgaact ttattggtgg ttggataact gattttacta ctggatttgt atgcagacag
     6541 caaggaatcg ttcttagcaa aaaagtagag ctttcagttg attagagaaa ggagagtttt
     6601 aaatgtatgg tgatattaag atcgtaagag gaaacggcgg gtatggaggt cctttgatta
     6661 ttaggccgac aaaagataaa cacaagttca tctatgtcac aggtggaggt gagaggccaa
     6721 tgatcgtaga taaaatagaa gaactgacag gtatggagtc tatcaatggg ttcaaaacat
     6781 caatacctga tagtgaaatc gcgcttgcaa tcgttgactg tggagggact cttagatgtg
     6841 gaatttatcc taaaaaaggg ataccaacca tcaatatcgt ttccacagga aaaagtggcc
     6901 cattagcaca atatatcact gaagatattt atgtttcagc agtagggtta gaacaaatac
     6961 agccactaat ggaaactgat gataacaaag aaacagtaaa tactgcatct ccagataaaa
     7021 agtacaaata tgatacttct aaaaagataa ccgagcaaaa agcagagcag caaaactgga
     7081 tagcaaaaat tggaatgggc gcgggaaaag tagttgctac attcaatcaa tcagcaagag
     7141 aagcagtaga tacgatgatc cggacagtga tcccttttat ggctttcgtt tcccttttga
     7201 ttggtgtgat acaaggttct gggatcggta atgtatttgc taacattatg gcacctttag
     7261 caggaaatgc agttggatta acaatcattg gctttatttg ttcactgcca tttttatctc
     7321 ctttgcttgg tccaggggca gttattagcc aagtgattgg aacattgatc ggtgtagaga
     7381 ttgggaaagg aaatattcct ccccaattag cattaccggc actatttgct atcaatactc
     7441 aaaatgcatg tgattttatt ccagtcggtc taggtttgga agaagcaaaa gctgagacag
     7501 tagaagtagg tgtaccatca gttctttatt caagatttct taacggcatc ccacgagtta
     7561 tcattgcttg ggtagcaagt tttggattat atagctgagt ttagtctaat ggtgataagt
     7621 caagatgaaa tttaagattt tctttattga gtaatatgtt ttgaagcgca cgaaactaga
     7681 cccgatcaaa atcaaatttt tttcgggttg attcaaggat ttgcgtcaat aacggattgt
     7741 tatttctcta tcacactcct tggtggcgta tagagttggt gtttacgtag tagcgtatcc
     7801 accagacgcg taaattttct tgcggttagg acgagtgcac gtttgtgttg atgctttgga
     7861 acctccttat atttactttg ataaaaagct ttgtattcag gaagataatt ttttacagag
     7921 ttggcagctt caactaagta gtatctaaaa tatcgatttc cttgttttgt cagaggtgta
     7981 ttttgcgact gatagtttcc agattggttc actttccaac ttaatccagc gtattttgcc
     8041 aattttgtct gatcttcaaa tctttcgatt tgaccaattt cagcgattaa accggcagca
     8101 tagactttac caacgcctgg aatactggtt aagcattgat attctggaat gacaacaatt
     8161 acttgttcga tggctttatc taattctttg atattttttt caagtgctcg tatttctcgt
     8221 acgagaacac ttaaaacaac attaattgat tcttgtgcaa gagcacctag gcggtaactc
     8281 atggtaattg cacgttgaat tgctttagcg attttttctg gttgcttgaa acggcctttt
     8341 cctttttctt gaagtaaatc acagaaagct tctaaaggaa gctcagcaag ttcatccaat
     8401 gtgaaatctt ccgtcatgag tgaaatgagg gttgcactaa aaagactcgt cgattcgtct
     8461 cgcatttctc gagcaagcgt attacatttg tacgttagat tttcaagaaa atgttgcttt
     8521 gtacgaatca attgcttaat aagttgatag cgagtacgtg ttaaacgctg taaggccatg
     8581 tatttctctt ctttgatagg ggaagttgtg aatcgttgaa tacgcaagaa atcagcgatt
     8641 cttaatgcat cgtttcgatc agttttattc tcatcaaaca tgcgactaaa ttgtttcacc
     8701 cgaaaaggat tttcaatcgt tacaagtgtg ttgagcttct ttagtttctc atcttcatga
     8761 aaaaacatgg aaggatggaa gctgtacatg gacgttgact ccatgccaat cacaa
//
LOCUS       DACCVZ010000107         8748 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.110, whole genome shotgun sequence.
ACCESSION   DACCVZ010000107 DACCVZ010000000
VERSION     DACCVZ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.110"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(106..552)
                     /locus_tag="IVW63_002550"
     CDS             complement(106..552)
                     /locus_tag="IVW63_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAP7860787.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(579..755)
                     /locus_tag="IVW63_002551"
     CDS             complement(579..755)
                     /locus_tag="IVW63_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAP7860788.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(917..1345)
                     /locus_tag="IVW63_002552"
     CDS             complement(917..1345)
                     /locus_tag="IVW63_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP7860789.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            1437..2297
                     /locus_tag="IVW63_002553"
     CDS             1437..2297
                     /locus_tag="IVW63_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAP7860790.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLKQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            complement(2389..2682)
                     /locus_tag="IVW63_002554"
     CDS             complement(2389..2682)
                     /locus_tag="IVW63_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAP7860791.1"
                     /translation="MPDTQKSKVEKVSQLFKMLSDPTRLKILLYLKDGEQNVTAITQA
                     VEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHVLDILNQTLKHVEHQ"
     gene            complement(2754..4481)
                     /locus_tag="IVW63_002555"
     CDS             complement(2754..4481)
                     /locus_tag="IVW63_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAP7860792.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEEAKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            complement(4695..5621)
                     /gene="trxB"
                     /locus_tag="IVW63_002556"
     CDS             complement(4695..5621)
                     /gene="trxB"
                     /locus_tag="IVW63_002556"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAP7860793.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(5766..7199)
                     /gene="ascB"
                     /locus_tag="IVW63_002557"
     CDS             complement(5766..7199)
                     /gene="ascB"
                     /locus_tag="IVW63_002557"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP7860794.1"
                     /translation="MGFRKDFLWGGATAANQCEGAYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQVKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(7199..8602)
                     /locus_tag="IVW63_002558"
     CDS             complement(7199..8602)
                     /locus_tag="IVW63_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP7860795.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLSADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
BASE COUNT         2392 a         1950 c         1478 g         2928 t
ORIGIN      
        1 agctagaaga aagaataaga ttctttcttc tagctgtttt ttagttcttt ttttacgaac
       61 acaaaaaact gcggacaatc actgtccgca gtttaaatga taaaattaag attgtaatag
      121 ttctttcaca atcgcattca cttggtttcc atctgctttt cctttgactt taggcataat
      181 tgcacccata actttgccaa attctttcat tgatgaagca ccagtttgag tgattgcttc
      241 ttgaacaagt tgtcgaattt cttcatcgga aagttgttcc ggcatatatt tttcgactat
      301 tacaatttca ctttttactt tttcagctaa atcgtcacgt cctgcttctt caaactcatg
      361 caaagaatca cgtcgctgtt tcatttcgcg agacaacacc gttagttctt cttcttctgt
      421 caagtcgtga ccttctttaa tctgctcgtt ttgtatagat gacttgatca ttcggatgac
      481 ttgtaaagat tccttatctt tcgctttcat cgctgctttc atgtcatcgt ttaatctact
      541 tagtagtgac acactaccaa ctccaattca tcacagaact agaatttttt gcgttttcta
      601 gctgcttcag attttttctt gcgtcttaca cttggttttt cgtagaattc acgtttacga
      661 gattcttgta aagtacccgc ttttgacacg gaacgtttga agcgacgaag agcatcgtca
      721 agtgattcgt ttttgcgaac gactgttttt gacatgttaa ttccctccct ccgagcttaa
      781 aaagtaaccg taattgttat tgaaatatat ctcaaaaaac aagactgtcc tgtaaatatt
      841 atatctaatg ctgttttgac cgtcaaggaa atcttgcttt tttttaaaat tatcaaatgt
      901 tattttattt aaacccttat tgacaatttt cacatcttcc gaaaatctcg aatctatgcc
      961 cttcgatcgt gcatccacct agctgttctt cgaaataatt catcggacac atatggattt
     1021 ctttcgttgt tccgcacact gtacagataa aatgatggtg atggccgatt tccccctgac
     1081 agcaatgaaa acgaaacttc atttctccat ttaaatcggt ttcttccagt aaatcgatct
     1141 ctgcaaaatc atggagattc cgataaatcg tatcataact tacccctttg aattcctgat
     1201 tcatatagtc aaaaacttct ttagcagata cgtagcggtt acgcttcact aaataagtta
     1261 acaatgcttc tcttttttta gtatatttaa aaccgttatt tttcaatgtt tctaatgatt
     1321 gttcgatcaa tgtctgtttt ttcatgactt attcctccaa atcaaaatga ttacgaagta
     1381 cgcattctag agtatggtat aataaacata aaaaaaatgc aagtgaggtt ttatccatgt
     1441 cttccgattc tacagaaatc gttacttttt ttgtcatctc cgactctgct ggagaaactg
     1501 cgacaaaact agcgcaagct actatggctc agtatcctac cgttgagttc aacctattcc
     1561 gcagaacgtt cgtgacagat gaaaaaacat taaagcaggc attgcaagat gcattagaag
     1621 aaaaagcact tgtcctgcat acattaatca atcaagaact gatcgagata acacgttctt
     1681 tttgtgaaga acatcaatta tttagttttg atgtgatgac gccaccgata tcagaaattg
     1741 aacgtttaac cggtatcaag ccaattcggc aacctggtgc cctccattta ttgaatgaga
     1801 actatttcaa acggatcaaa gcaatggaat ttgctgtaaa atacgatgat gggaaagatc
     1861 ctcgtggttt tttagaagca gatgtcgttt tgctaggcgt atcccgaact tccaaaacgc
     1921 ctttgagctt gtttttagct aacaaaaatt taaaagttgc caatttacct ttgatcccac
     1981 aagcacatat tcccaaacag ctttgggaga tcgatcctaa aaaaatcgtg ggactaacga
     2041 ataacccaga tattttaaat aatatccgta aagaacggat gcgctcttac ggattaaacc
     2101 ctgatactgc ttattccgat atcgaaaaaa ttagagctga actcgatttt gcgaatgatc
     2161 tttatgaaaa actaggatgt gtagtgatca atgtggcatc tttatctatt gaagaaacgg
     2221 cttcgcttat tttgaatgct ttagacctag aagatcatag ttattatgga actgaaacaa
     2281 cagaaaaaag cgattaatca tttttgtctt tttcttaaaa aacactggag tgtgacaacg
     2341 aagaaatttc gttgtcacac tccagtgttt atctatttgc acctatcgtt attgatgttc
     2401 cacatgtttg agtgtctggt tcaaaatatc cagtacatga gaatcatcaa gactatacaa
     2461 aatcgctttt ccctcgcgat gagacttgac gacatgattt tctcttaata aacgtagttg
     2521 atgcgataca gcagactgct ccatttccac tgcttgggtg attgctgtca cattttgttc
     2581 cccgtctttc agatatagca gaattttaag acgagtggga tcactcaaca ttttgaataa
     2641 ttgactgact ttctctactt ttgatttttg cgtgtctggc aatccattca cctccaactt
     2701 gaaaaaagac tgacttctaa agtttaccac tttttccatc agtctcaagt tttttattct
     2761 tctgtcatct ttttgataat cgcttcataa gaggctactt tttcggctgc gtcttctgta
     2821 gagcttcctt ttacaccaat ataaaacttg attttcggct cagttcctga agggcggata
     2881 gcaatccagc cattttcttc caatgtatat ttcaatacgt cggatggcgg tgttgttagt
     2941 ttttctacgt ttccttcacg gtctgttctc gtcaattctt taaagtcttc tgtttgaata
     3001 acttttgctc cggcaaattc tgtcggtgct tctttacgga atttttccat caaagcagag
     3061 attttcgcag aaccttcttg tccgctcatt gtcacagaaa tcgttttttc tgcaaaatag
     3121 ccataggttt caaaaatcgt ttgcaagccg tcatacaacg ttttgccttg ttttttatag
     3181 taagctgcta cttctgctaa taaaagcaat gcttggatcg cgtctttatc gcgaacaaaa
     3241 ggtttaacta aataaccata actttcttcg aatccaaaca taaaagtatg tgaatggtct
     3301 tcttcgaatt gttggatttt ttcagcaatg aatttaaacc ctgtcaacac attgaacatg
     3361 gtagcaccgt agtgttccgc aattgctgta ggcaattcgc tggaaacgat tgatttcaat
     3421 accgctgcgt tttctggtaa agtgcctctt gattgatgtg cttccaaaat atattgagca
     3481 aacaatgccc cgatttggtt cccagtcaat acttcataag aaccatctgg caaacgaacc
     3541 gctgcgccta aacggtctgc atcaggatct gttgcaatca gcaagtcagc tccttctttt
     3601 tctccaagtc gtatagcata ttcaaaagct gaatgttctt ctggatttgg cgatttgacc
     3661 gtagtgaaat ctggatctgc cacagcttgt tcgggaacta gtacgaattg ttcgaatcca
     3721 gcttgtttca acgcacgttc gcccaacatt ttccctgttc catgaagtgg cgtgtacaca
     3781 agtttcaaat ctttccccat tgtttctacc aattcacgat caatcgtcac tgctttgatt
     3841 tcttctagat aagcagcgtc cacttcttct ccgatgatcg tgatcaaccc gctatgttta
     3901 gcttcttcgt cagataatac ttcgactttt agcggattgc tgacttcacg gacatatttc
     3961 gtcaatgcat ctgcgtctgc aggaggcatt tgtccgccat cttctccgta gactttatat
     4021 ccattgtaag ccgctgggtt gtgagatgca gttaccatga ttcccgcaaa cgtcttcaaa
     4081 tgacgaactg caaaagaaag ctctggtgtt ggacgcagac tttcgaatac ataagacggg
     4141 atattgtgat gtgccagtgt tttggctgct tccattgcaa attctggtga ctgatggcgt
     4201 gagtcataag caatagcgac acctcggcgt tttgcttctt caccttgtgt atccatgaaa
     4261 cgtgctagtc cttctgttgc ttgtcttacc gtatagatgt tcattcgatt gatcccaggt
     4321 cctaagattc cccgcatgcc tgcagtaccg aattccaacg gtgcataaaa agcatcttca
     4381 agtttttcag gatcttcacc cagatcattt aattgttttt ttaagttttc ttctaaattt
     4441 tcttcatgta cccattgttc atacacttgt tcccaagaca tgaaaataac acctctttct
     4501 gaaatatggt tcttaataag tatagcattc acttattaga tatgaaagta tgaggaccaa
     4561 aaaacgctta aatcaagaaa ggattctttt atcaaaaggt gttggacgtg ttcgcataaa
     4621 tcagattcag taaatttcac gcgaaaaaaa agagtaaaag aacaattgaa cccgttcttc
     4681 tactcttttt aaacttatgc agttgtttct tctaaagatt ccaagtattt atacacttgt
     4741 tgtccagcaa taccgccgtc accaacagct gtagtgattt gtcgcaaatc tttttcacga
     4801 acatctccga tggcaaaaac gcctggcata ttcgttttca tttcgttgtc tgttggaatc
     4861 cagccagctt cgttcgtcaa acctgcttct ctaaaaggtg cagttaatgg atccagtcca
     4921 acatagatga atactccgtc tgctgctaaa tcaaattcat tgccggtttt gacattacgt
     4981 gctttcacac ctgtcactac catttcgttt ccaacgattt cgtcaacgac tgtatcccac
     5041 ataaaggaaa ttttttcatt tgcaaatgca cggtcttgga tgatcttttg tgcacgtaat
     5101 tcatctctac ggtggacgat cactacttca gaagcaaatt gtgtcaaata gatggcttct
     5161 tctactgctg agtccccacc cccgatgact actagacgtt tgttacggaa aaacgcacca
     5221 tcacagactg cacagtaaga aacgcctcgt ccagcaaatt cttcctcgcc aggtacgcct
     5281 aatttacggt ggatacagcc tgttgcgata atgactgttt ttccttcgta acttttatct
     5341 tcacagatga cttctttatg gctgccgtga tccttgatat cttgaacgat tccataagca
     5401 ttttctgtcc caaatcttga gacactttca tacatcttat aagctagatc ggggcccatg
     5461 atcgaatcga atccaggata attttcgatt tctgccgtat tgttcatttg gccgccaggg
     5521 gcaccttgtt cgatcatcaa tacggataag tttgaacgtg aagcatataa agcagcagtc
     5581 atcccagcag gacctgcgcc aataacgatt acatcataca tatgtagatt ctcctttact
     5641 taatcaagta agcatacttt acagccaatg cgaaaaaaag tctattgttc tgcttgcgtt
     5701 tctcgaatag ctttattata ctcgaaaaat ccgctgaaaa acaatagact tttataaatc
     5761 attgatcaat cgttcgaaag attttctcca tttgaatcaa ttactttttt ataccagttg
     5821 aatgattttt tctttgaacg ggctaatgtg ccatttcctt ggttatcacg atcgacataa
     5881 atgaatccgt atcttttctt catctcaccg gtaccagctg atactaaatc aatacatccc
     5941 caagtcgtat agcctaatag atcgactccg tctagttcta ctgcatcctt catcgcctgg
     6001 atatgcgctg ccaggtaatc gattcggtaa tcatcttcca cataaccatt ctcatctggc
     6061 gtatcgactg cacctaagcc gttttctaca ataaataatg gtttttgata acgatcataa
     6121 atatcattca tcgttattct caagcctaat ggatcaattt gccaccccca ttcacttgct
     6181 tgcagatatg gatttttgac agaagcaaag atatttcctg cagtctgttc caagagttcg
     6241 ttgtcggtag tcgaaactcg ggaagaataa taagaaaaag agataaaatc aacagtatgt
     6301 tctttcagca atgcggcatc ccctggttcc atttcgatct gaatgccatt tcgttccatt
     6361 tctttcaatg cataagctgg gtattctcct cgtgactgaa catcaatgaa gaaataattt
     6421 tctcgatctg attttctaga agcccaaaca tcttcaggat tgcaagtgta tggataatat
     6481 gctcctgctg ccagcataca gcctactttg ttctccggat ctacttcatg agcaatcttc
     6541 gttgcgatgg cacttgcaac caactcatga tgtgccgctt gatatttgac ttgttcttcg
     6601 ttttctcctt cttcaaagta cagtcctgct cccatgaatg gtgcatgaag gatcatattg
     6661 atctcattga atgtcagcca gtatttgaca agtcctttat atcgattgaa gatgactcga
     6721 cacagatttt cataaaaacc aacgagttct ctggaacgcc acgcaccata ttctttgatc
     6781 aaatgcattg gacaatcaaa atgcgtaatc gtcacaagtg gctcaattcc gtgcttttgg
     6841 cattctttaa agacatcctc ataaaatttc aagccagctt cattcggctc tttctcatcc
     6901 cccattggaa aaatacgact ccaggcgata gacattcgat aagtcttgaa ccccatttct
     6961 gcaaacaaag caatatcttc tttataacga tgatacatat cgattgcaat ttttgctgga
     7021 taaaaatgat cctcatcaaa ttcaaacatt tttttctttc cggtgataac aggaaaacgg
     7081 tcttttccga ttggcacaac atctacgttt gctagtccgc gtccaccttc atcataagcg
     7141 ccctcacatt gattggctgc tgtagcaccg ccccataaaa aatcttttct gaaccccatt
     7201 atacttcctc cattatatgt gtattacctg ataattctct tgccagttca tcttgaactt
     7261 cgattccttc ttcttttaat cggctgattg tttccttgaa ttgcggtaaa tactgctggt
     7321 gtgcaataaa caactcatcc atgatccgtt ttgctgtctt tcctgatcgt ataagtggat
     7381 tgatcgtaaa cgcctgtaaa gctgtcccat aatcaccagt cacagctgct tcgatcgtca
     7441 gcaattccat attcttcatt acttgcaacc agcctctttc agcagcagga agagaaccaa
     7501 acgctacatt tctcgctcct tgtgcgccaa cataggcagt gacttctaca acacaatctg
     7561 ccgacaggtc aggaacagct ccatcattct ttgtagatac aacgatctgt gtttctttat
     7621 ttccatagat tgaagcaatc gtttcacagg cagcgtctga ataataagcg ccacctcgtt
     7681 tttgcaattg ttcaggttta tggtctaatt ctggatcttt gtataattca aatagctctg
     7741 cttctgtttc tttcacttgc tgcgctcttg taccaatcgt ttgatattct tctaaagcat
     7801 gttccagcat ttcttcttca cgatagtaat agcggtggta gccacaaggg atcatgttca
     7861 tttgttttaa ttgttctttg aaaaacggga tatcaaagat atttttcggt aatccattat
     7921 cttcatcgta taaacgatca atcaattctg ccgtgcggtc atttccttta ttatctgcta
     7981 ctttgtgcca atggaaatga tttagaccgg caaacttgta gatcagctct tcttttttct
     8041 tgccaagcat tgctggttct gtcatcatcg ccatcactgg cacattgcat aatccaatca
     8101 ctttatccca tttgccatat ctgataactg cttctgtcac catcccactt gggttcgcga
     8161 aattgatcag ccaagcattt ggacataaac gcttcatgtc ctcaacgatt gccaaaacga
     8221 ctggaacggt acgaaaagct ttgaatatcc cgccagcacc atttgtttct tgcccaatca
     8281 tcccataata actagggatc cgctcgtctt tgattcgtgc atctaattga ccgacacgaa
     8341 actgagtcgt aacaaaatcc gcatctttca atgcttcttc ccgatccaga gttgcataga
     8401 tcttgacttc atatggagaa gcatcccaca tacgctgaga catctgacta acgatctcaa
     8461 gcttttcttt tccttcttct acatctacga gccagatttc tcgtatcggt aattcctcat
     8521 atcttttgat aaatccttcc atcaactcag gggtgtaact gctgcctcca ccaatcgtag
     8581 cgattttgat tccttttgcc atgttctcac tcctttactt ttttacactt tcattatctt
     8641 ttttgtaaac aaaacaaaca atagaaatcc gtttctttcc agtaacattt acaaaagtta
     8701 ctgttttcta gtggattttt gtaaatatct tgtcaaaaaa agcctatt
//
LOCUS       DACCVZ010000108         8684 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.111, whole genome shotgun sequence.
ACCESSION   DACCVZ010000108 DACCVZ010000000
VERSION     DACCVZ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8684
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.111"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(557..1597)
                     /locus_tag="IVW63_002559"
     CDS             complement(557..1597)
                     /locus_tag="IVW63_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAP7860796.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSSYSEAQQTVQTIHNAKRKAEELEQTIVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1945..2271)
                     /locus_tag="IVW63_002560"
     CDS             complement(1945..2271)
                     /locus_tag="IVW63_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860797.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNYKPKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2258..3046)
                     /locus_tag="IVW63_002561"
     CDS             complement(2258..3046)
                     /locus_tag="IVW63_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP7860798.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQG
                     NATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVG
                     SEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKL
                     SETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRT
                     ITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3412..3702)
                     /locus_tag="IVW63_002562"
     CDS             complement(3412..3702)
                     /locus_tag="IVW63_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAP7860799.1"
                     /translation="MSINTFVYSHPINVYIIKYLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3838..4017)
                     /locus_tag="IVW63_002563"
     CDS             complement(3838..4017)
                     /locus_tag="IVW63_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860800.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLFI"
     gene            complement(4014..4364)
                     /locus_tag="IVW63_002564"
     CDS             complement(4014..4364)
                     /locus_tag="IVW63_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860801.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRANQNLAKEQMRTE
                     EIAEILNASVIKNRSVCIQKEERNAEGYYPDDIVGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4357..5682)
                     /locus_tag="IVW63_002565"
     CDS             complement(4357..5682)
                     /locus_tag="IVW63_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP7860802.1"
                     /translation="MLDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKNLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYQNVPDKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIKDLANWNPYTIKSRLGVIGLQLYFHANGIDRTDIAIAPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHHCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTRELQDYCLFLFNKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDDEK
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            complement(5791..5994)
                     /locus_tag="IVW63_002566"
     CDS             complement(5791..5994)
                     /locus_tag="IVW63_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAP7860803.1"
                     /translation="MKEQQLGYTLWGRPLYGLERRTAVSIDCACGELIQLNIQTKQYN
                     CKNCGNCYQFIDQDFQLLNEKNK"
     gene            complement(6154..6729)
                     /locus_tag="IVW63_002567"
     CDS             complement(6154..6729)
                     /locus_tag="IVW63_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7860804.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMDRDMIVERTQEGKLFAKKNNPNFKEGRPKATITPKKRHAYELI
                     TSGKSYKEVEAITGFSRSTLFRIKKQIEASE"
     gene            complement(6745..7350)
                     /locus_tag="IVW63_002568"
     CDS             complement(6745..7350)
                     /locus_tag="IVW63_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein Fic"
                     /protein_id="HAP7860805.1"
                     /translation="MILENKLGLTNQVELAKAEEKLSKQKAKELYDSGKINEIEVGTF
                     KGLSEIHDFLFSEIYDFAGKIRTVNIAKGNFRFAPVMYLEQSLNHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            complement(7437..8258)
                     /locus_tag="IVW63_002569"
     CDS             complement(7437..8258)
                     /locus_tag="IVW63_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP7860806.1"
                     /translation="MYQFLKTGATILNYYQQYKENKKRCGRRSIALPEEQKEYVQKRV
                     VQGWTPDVIVGRSEMKLDCSVRTLYRMFQTGAFNVRDLPMKGKRKPNGHQEKRGKQAF
                     RRSIHERIKEHPEFENEFGHLEGDTIVGRKHKSAVITLVERLSKVIITLKPAGRQAMD
                     IENRINHWFQTVPKHLFKSITFDCGKEFSNWKAMGNQNDIDIYFADPGTPSQRALNEH
                     SNGLLRRDGLVKAMDFNEVSESFIEYRKHFLYSILSSFKFSIDYIYCEFCRGSET"
BASE COUNT         2544 a         1631 c         1330 g         3179 t
ORIGIN      
        1 ttgcgggtaa taccgtaaca ctgaagggca cgcattaagg cgtcatctta atgctttcct
       61 gtaggacact gacggagatt accagtctcc cgagccttac aggggccttt cttttttttg
      121 tattttcaat tatcacaatt tatcgtccaa aagtgcagaa cgaaaatcaa ttcatcacaa
      181 gcatatcaga caattaaatt taaaacaact aaaaatatac aaaaaagtgt aattgaatat
      241 tagcagcact gcctgaaaag aagtaatatc aggcttttca gcttggggaa ataagtgaat
      301 tacctctctt catgaattat tataactcaa aaaagcacat atgcaaacac tagttcccta
      361 tttttttgaa tgaaaaataa ctaaaatatc taacgattat gactttaaaa cctacgtttg
      421 tgattgtttt cataaacttt taatctaaaa actccggaat aataactatt tatttgtaac
      481 atttgtaata aaattaaaat cataaaaaag ttctaattta aaattgatca tttttatagt
      541 gatcgctttt tatcaactac tctagccaat tttccgtact aactgttggt aattcgttaa
      601 atgtttctct ttgttcgttt gcaagctttg ccgcaatagc tttttcgaca aaccaatttt
      661 ttacataaac gaaaattaga ttctgcaaat tgtttacttt ttcagttttt tgtttttgat
      721 aagctttcag taaagtcata tataatcctt tgtcagcatc aattccataa gattcaagtt
      781 cttcataaac aacaatagtt tgctctaatt cttcagcttt tctctttgca ttatgaatag
      841 tttggacggt ttgttgagct tcactgtaac ttgaagaaaa tgtttttatc aagttcaata
      901 cattttctgg tacaaatgta tttatactgt cctctttcat gatgtcgacg aagttatcta
      961 gtaaaacttg attttgtaac tgatcagttt cagtgtctat tatgtgtcta ttagtgtcta
     1021 tagaattaga atagaataga ttgtctgcga ttttcgcaat tacggttgag tccttgatat
     1081 gactggattt tgccgtattt gcgattttcg caattacggt ggtatcattg atttctcgcg
     1141 gttttgccgt atttgcgatt ttcgcaatta cggtggtatc agtattgtct tcctcttcca
     1201 tgattttaaa gacgtcttga ttcgttactt ctggcttgcc taagtacaat aaattaggca
     1261 tagattcaat cttaccatca cgtttattta ctcttcctct cttctgtttc agaagacctg
     1321 ctttttctaa ttcctttttg attttagata ctttaccttc gcggcattgt aacagtttca
     1381 ttaattcttc aactgtgaat atgaagaata tattatcatc agaatctacc cagttatttt
     1441 tgactgaata atcaaatcga tctttaagta gcatataagc aatttttgca tcatttgata
     1501 gatccatgta tttttcgtta gtaaaaaata ccttaggcat ttgataatat ttttcacgat
     1561 aaatttcttt tgatttgtaa taattaaaat cattcatagc caatcctctt tctgtaggat
     1621 agcgttttgt tcaaaactgt gttacaatga attaaacaaa tatatctatc cactatatat
     1681 tttctactgc tgataagtcg ccaaactttg ttaaagcagt agtctttttt tatctttttt
     1741 tagtttacct taaaaaataa attaaagcaa accgctctat ttcaaggttt aagctcatat
     1801 caactatatc acgatattac aataacatta tatcacgata ttgcgatatt acaatatgaa
     1861 gataagcgac ttatcagctt tgatactact gctttttata aaaaaaatat cacgatatta
     1921 tgatatcgtg atattgaatg taaattaaat tttattttgt ttctttgcta gtttatatcc
     1981 ttcaatcaag tattcttcag gtatggattt taatagcgca tcttctataa cgtctggttt
     2041 acttttgtct gattcagcaa tagtcgtcca atatttgagt gctgacatta gaattggatt
     2101 tatgcgaatg ctatctgctg ttcttacact acttccttga tcttttatga ctttacttat
     2161 atttttcttg gttaattcga tttcttctac ttcttttggt ttgtagttct ttttattttt
     2221 atttcctagt agtctactta ctgcagcttg actgcgatta tcttctgcca tcaaaatcac
     2281 caacttcttt taaatattct tctgtaaatg ctttatagtc atcttcagct gttgagggtt
     2341 tattaaaatt gattagatct gatccagcag cttgcgcttc gtcaacggtt attgtcctac
     2401 gaatataagt tttgaaaatt tttgcaccaa tgactctaga aatttcggtt gctgcagacg
     2461 tcatttcttt agaaatgtta taacgcttat tatacttagt aaataggact cctcgtactt
     2521 caagcttgtc gttcgtatat tcttttaccg tttcaatagt ttcacttaac tttattagtc
     2581 cttttaatga gaaatacgca gcttcaactg gaatgataat ttcatcagaa acagtaaatg
     2641 cgttgactgt aagcattcct aaacttggtg gacaatcaat tataatataa tcatagttgt
     2701 ccttgattgg ttgaagtact cttttaagcc tgtgttcact tcctacttga gtaaattccc
     2761 tttctgcaga agaaagggct atgtcggctg gcaaaacatc aattccttta tagtccagaa
     2821 tagcatctgt aatgtcagcc tcccctttta atacttcata aattgtaggt tggtttgttc
     2881 catctatatc gaaacctaca ttatctgtag catttccctg aggatcaatg tccactaaaa
     2941 gtacattttt accgtaaaca aatttcaaac atgctgctaa attaacgcta gtcgtagttt
     3001 tagaaactcc acctttttga ttggctactg acaatattct tgccattaaa atatccccca
     3061 ttcgtcttat attataatat aattatatca tgatattgtg atattgcaat atcgtatttg
     3121 cattatattg taatattgtg taattatttt gttttaaaga tatatatcgg ttcggatata
     3181 aagatcattc atatgttatt cgaaattaaa ataatcactt tttttaattt aaaatttttt
     3241 actaatgata agaaatatgt tttgtgagca gcaactagaa taatttaaac attactaaac
     3301 tgtctatatt gttactaata attcccttct tatagtgcat tttcttagaa aaaacaatat
     3361 tacgatatca tgatattaag atatcgtaat attatacaat tgtgattgat attatatatg
     3421 tttttttatt tttttatcat gtttaatctt gaaggaatca tattcttttt ctaaagacag
     3481 gagcttttca taaacatcag acatgttcaa actagaggcc aggcttaaat cataaacgaa
     3541 tgaagcaggt aatgatttta ttctacgttg tcgggttatc cagcttgcaa ccgttccttg
     3601 tgggtaggca tataactcac aaaattgttc tacagtgatt cctaaatatt tgataatgta
     3661 aacattgatc gggtgcgagt aaacaaatgt attgatggac atggtgcgta agcctacttt
     3721 cttttattat tgcgtttgca ataatagttt aacacacgca ttattctagt atctactcct
     3781 atttgtaaaa acaaaaaagg attcatagag ataactctat agaatccgta aaatacctta
     3841 tataaataac gggaaaatat aaaacctaaa attatgataa cctgctgcag cttctacata
     3901 gaaagagaaa cgctcaacac caacctcatt tatcaaacgt tggccatacc cccaaatctc
     3961 ttctgatagc tgatcaaagg ttatatactt tagctcatat tgctggataa tgttcattct
     4021 aatcgactcc atttattatc ctggtaaaat tcgatatgac gtatttcgtc gtagtgaatt
     4081 ttgtctttgc caacgtagat tcccagctca tcactaccta agatctttcc aacaatatcg
     4141 tctggatagt atccttcagc gtttcgttct tctttttgaa tacatactga tctatttttt
     4201 atgactgaag cgttcaatat ttccgcaatc tcttcagtcc tcatttgttc ctttgctaaa
     4261 ttttgatttg cacgttgctc attatctgca tcgatctctt cagtatgatc cgataaatag
     4321 aaacctgccc atttcaatcg tcctcgatcg ttatagtcaa tcatttttaa gcccccctgc
     4381 gccgcctgca tggccaccaa ccaacgtgct tctagtaata ctacgagcgc cttctaacat
     4441 cgaagaagca tgtacaattg acgtaaaacc atacttctgc ctaattttat ctattatttt
     4501 gtctagtttt tcgtcatcaa tctgtttttg tggatcacta aacaaatcca gctgaagcga
     4561 atcagtataa actagcttgc tgtaagtgat tccgacatgg cggacttctt gtccctcata
     4621 gtatttatta aataagaaca gacaatagtc ttgtagctct cttgtattat ctgtgatagg
     4681 tatcttcatc tggtgtgaaa accctggtct cgtttctaaa atcgacgttc caatgtgtaa
     4741 atgaacacaa cctgttttac agtggtgttg cctaatacgg attgctactt gctcagccat
     4801 ttcttttacg accagttcga tttcatttct tctagtataa tctcgtggta gcacttgtga
     4861 attgccatat gatttttcct ttgtcggttc tggtgcgatt gctatgtcag ttcgatcaat
     4921 accatttgca tggaagtaca gctgtaaccc aatcacacct aaacggctct taatggtgta
     4981 tggattccaa ttagctaaat ctttgatact catgatcccc atttggttga gccttttttt
     5041 cattcgagaa ccaatacccc aaaagtctgt catttcagga atattccata ctttatcagg
     5101 aacattttga tacgtccatt cggcaataaa tccttcatta tgcttcgctt cattgtctaa
     5161 ggctagttta gccaaaagag gattatcgcc aacacctact gtagcaatca atcctagctc
     5221 ttctttaata cgttcttgga tcatttgagc gagattcttc cttcgctgac ttcgtgttcc
     5281 ttcagtcgta aaaagattca gtgatcgggt cacttttaag attgattcat cgatcgagta
     5341 aatcagtaga tcttcatcag ccacatatct tctgaaaata ttatttacct gcatattacg
     5401 cttaatataa aggttcatac gtggtggaac aacatgtaat gttttaggga aaggctgtgg
     5461 tagatcccgt ggtctgctga cattagaaat accatatttc ttctttgcag ctggtgaaga
     5521 agctaaaatc aaccctgatc ctgtattatc cgctcgactc atgacaacta attcagtcgt
     5581 taatggatct aaatttcttt ctatacattc gacacttgcg taaaaacttt tcatatcgat
     5641 tagaaagtag tcattgactg gctcttttga gtaatcaagc ataaagttct ccccctcttc
     5701 tctcatatta tacaaacata cgttcgtgtt tgcaacgagg atcttctcta aatagaaaaa
     5761 tagccagaca attgtctgac tataataaac ctatttgttt ttttcgttta gcaattggaa
     5821 gtcttgatca atgaattggt aacaattccc acaattttta caattgtatt gtttcgtttg
     5881 aatattgagt tgaatcaact caccacaagc acagtcaatc gatacagccg ttcttcgttc
     5941 taatccgtat aatggacgtc cccaaagagt gtagcctaat tgttgttctt tcatttactt
     6001 cgttcctccc taaaaatatg tctattcgta gctggtatga cgcttcgttc gaccaatgat
     6061 acatcttaat gagtgaacct gaccttagaa tgctcgtata aacaacgatt tatttgattt
     6121 aaaagagatt tttatattaa ttttatcaat cttctactca ctcgcttcta tttgtttctt
     6181 aattctaaaa agtgtactac gactgaaacc cgttatggct tccacttctt tatacgattt
     6241 gccggaagta atcaattcat atgcatgcct cttctttggt gtgattgttg ctttcggacg
     6301 tccctcttta aaattaggat tattcttttt cgcaaataat ttcccttcct gagtacgttc
     6361 tacaatcata tcacggtcca tttcagctac actcaacaac gtacgtgtaa ccattcgacc
     6421 catcgatgta ttttcgatcg tccctagatt caatacctta atcgtgacgt tatcatcgag
     6481 taaaggttca atgatctcta gtgcttctct tgtattacgg gcgaatcgat caagtttcgt
     6541 aacaacgatt tcgtctccag gcttcagacc agccaacagc tgattaaact ttggccgatc
     6601 tcgtttcgta cctgtaaatt tttcagaaaa aatattcttc ttctcaacac cgttctcaag
     6661 tagctgttgt atctgttcct ttgtactttg agaagcggtt gagacacgtg catagccata
     6721 ttttgtcatt taactcacct gcttttacaa atcatctatc gtatactcag agtatccttc
     6781 atagaagtag ctgacatcga ttcctttcat atataactca cgatcgtcaa ttttatcagt
     6841 cagggcattg gaaatgagat agcgtatttc caagtcattt attggactgc gctccattgc
     6901 agaaagatag tctgctttat cgatcaagtt ccaatcgacc actttttgca attcttcctt
     6961 taaaatgaga tccagccaaa ttctagtact gcgcccgttt ccttcgcgaa aagggtgagc
     7021 gatattcatt tccacgtatt tcttaataat ctcttcgaaa gaagtttgcg gcatctgatc
     7081 aatatgattt aaagattgtt ctaggtacat gaccggcgca aaacgaaaat ttccttttgc
     7141 aatattaact gtccgaattt ttcctgcaaa atcataaatt tctgaaaaga gaaaatcatg
     7201 aatttcagac aagcctttaa acgtgccgac ttcgatttca tttatttttc cagaatcata
     7261 taattctttt gctttttgct tactgagttt ttcttcagcc ttggccaact caacctgatt
     7321 cgttaaaccc aatttatttt ctaaaatcat ggaaaatccc cttaactttt tgacataagt
     7381 ttatgaaaca ctacaaatcc tattgtatcg cgaatttaac catgtgtcaa aaactattaa
     7441 gtttctgacc ctctacaaaa ttcacaatag atataatcta ttgaaaattt aaaagaagac
     7501 aaaatagagt acagaaaatg ttttctgtac tctataaatg attctgatac ttcattgaag
     7561 tccatggctt taactaatcc atcacgacgt aataatccat ttgaatgttc atttagagcg
     7621 cgttgtgacg gggtgcctgg atccgcaaaa taaatatcaa tatcattttg atttcccata
     7681 gctttccaat ttgaaaattc tttcccacag tcaaacgtaa ttgatttaaa cagatgttta
     7741 ggaaccgttt gaaaccaatg attaattcga ttttcaatgt ccattgcctg tctaccggct
     7801 ggcttcaatg taataatcac ttttgacaaa cgttccacca atgtaataac agcacttttg
     7861 tgttttcgac cgacaatagt gtctccttca agatggccaa actcgttttc aaattctgga
     7921 tgctccttga tgcgctcatg tatactgcgc cgaaaagctt gtttcccacg tttttcttgg
     7981 tgtccatttg gttttcgttt gcctttcata ggcaaatcac gcacattaaa tgcgccagtt
     8041 tgaaacattc gatacagtgt acggactgaa caatcaagtt tcatttccga gcggccgaca
     8101 atcacatccg gtgtccaccc ttgaacaacc ctcttttgaa catattcttt ttgttcctct
     8161 ggtaaagcaa tcgagcgtct accgcagcgt tttttgtttt ctttgtattg ttgatagtag
     8221 ttcagtatcg tagcaccagt tttcaaaaat tgatacacgt tatgaatcgt ttgtcacgca
     8281 cgtcctaagc attgcgcagt tttggcaacg gattgattat ttttgaaata agactctatg
     8341 attaccagtt cgtctgttgt aagatgggtg taggtcattt gtactcactc cttaataatt
     8401 ctttggtcgg aactattttg agtgtagcac aaatgatctt tttagttgtc tagcttaatt
     8461 ttacaatcga cgaaaagaat actatgatga gattagtttg aaatttcatt ttgatgagta
     8521 gatattagga actgattgat agaacgaata agttatattg atattttgta tttgcagtat
     8581 ttgaaaaagt tgaagatgat aaggaaaata aagaaacaac aggaacagtc taacttgact
     8641 attcctgttg ttgaaaagat tatgattaat ttactacttt attt
//
LOCUS       DACCVZ010000109         8599 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.112, whole genome shotgun sequence.
ACCESSION   DACCVZ010000109 DACCVZ010000000
VERSION     DACCVZ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.112"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(132..1085)
                     /gene="menA"
                     /locus_tag="IVW63_002570"
     CDS             complement(132..1085)
                     /gene="menA"
                     /locus_tag="IVW63_002570"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAP7860807.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1098..2201)
                     /locus_tag="IVW63_002571"
     CDS             complement(1098..2201)
                     /locus_tag="IVW63_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAP7860808.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2291..3226)
                     /locus_tag="IVW63_002572"
     CDS             complement(2291..3226)
                     /locus_tag="IVW63_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAP7860809.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3528..5462
                     /locus_tag="IVW63_002573"
     CDS             3528..5462
                     /locus_tag="IVW63_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP7860810.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5919..6335
                     /locus_tag="IVW63_002574"
     CDS             5919..6335
                     /locus_tag="IVW63_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAP7860811.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            6349..6915
                     /locus_tag="IVW63_002575"
     CDS             6349..6915
                     /locus_tag="IVW63_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAP7860812.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            6938..7924
                     /locus_tag="IVW63_002576"
     CDS             6938..7924
                     /locus_tag="IVW63_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAP7860813.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(8079..>8599)
                     /gene="scm"
                     /locus_tag="IVW63_002577"
     CDS             complement(8079..>8599)
                     /gene="scm"
                     /locus_tag="IVW63_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAP7860814.1"
                     /translation="ASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDST
                     DTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTR
                     HASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGL
                     RITFMSYKKSKR"
BASE COUNT         2528 a         1654 c         1751 g         2666 t
ORIGIN      
        1 tgataaacgg tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatat
       61 aaggagctat ttttatttgg ctgttcttat tacttgatgc agggcagttt tttcacaacc
      121 tcttcatgct gttaaatggc ttgcataatg attgttagta atagccccaa tacataactg
      181 gcattgaata agaccatatt tttgatggaa tagctgaaac tgataggctg gggtaacgtt
      241 tgcttgaatt gatccaaatg cttcttcaca attggcaagg tcaagaaggt gaccaagatc
      301 ggccattcat agataccgct caacaacccc attaaaatca cgaaatagca agcatacatc
      361 aatagctgga ataagactgt tcccgcagga cgtccgatat aaaaaactag tgtatagcga
      421 tgattttcaa tatcacggtc aagatcccgc aaattattag ccaacatgat attggcaatc
      481 gtaaacacca agggtaagga agctaatacg attgctgcta tagcccaaag atttcctacc
      541 aaagcaaatt gtccagatga aaagttgact gtcagatcat agacatctga accgaatgta
      601 ttgacataaa cgaccatggc aaaaattcca aggcccatag tcaccccact gaaaatttcc
      661 cctaaaggca ttcgagataa aggaatcggt ccgaatgtat agaatactcc aataaaacaa
      721 cagataaatc ccatcaaaag taaaagccaa cccgtattga tcgttagaat aacgccgata
      781 acaaaaacaa atgcaatcat agctaaaatc atgtttcgaa tcaatacagg agatagattt
      841 ctgcggccaa tgacattttc ttcatactta tatacttcag aatgagcctt ttcataatcc
      901 atgtaattat tgatagcggt agtcgctaaa tcaaaaacta gcattccaat aaaaaataaa
      961 aaagtgttta gccaatgtat ctcatgaaaa aaagcgatag agaataatac ccctaccgca
     1021 aaaggaaata cactagccac ctttgttcgt atttcaacta cttctaaaaa gatttttagt
     1081 gtcatggttc gtactcctta ttttagttca gaacggtcac ccatcgtgta atgggagtcc
     1141 tccgataatt tgaaggtgtc tttgattgga tcggtcacat atactttatc gtcttttgtc
     1201 acgaagatcg cttccgtccc gttattcaat tcgctttcga cgtattccag tccttttttc
     1261 acacccattg aaaagactgc tgtagacaac ccgtcaccat caattgattt atctgttatg
     1321 atcgtgacac ttgcgatatc attgtcgaac ggataacccg tttttggatc aaacaaatga
     1381 tggtattttt tgccatctac ttctaaataa cgctcgtaaa ttccagaggt aactaatgtt
     1441 ttgttccgtt ctttaataga acctaaaaca gatccgcgag ccatgttcgg atcttggatg
     1501 ccgactgtcc agtcttggtt ttcgcctctt gggctgtggc ctaagacata gacattaccg
     1561 cccaagtcaa cgatggcagt ggtcactcct tgttttttca agactttcac tacttcgtcc
     1621 gtaatgtaac ctttggcgat tgcacctaaa tcgatgatca ttcctttttc ttttagataa
     1681 acagtttttt ctttgtcatt tagttcgatc ttatgataat ccactaattt caatgcctga
     1741 tcgatttctt cttgggaagg ttttctggcg tcatcaaaac cgattcgcca taattgtgtg
     1801 attgcaccaa tcgccatatc gaatccgcct tgagaatctt ggctatattc gtaggcccgc
     1861 ttgactaacg tgtagacgtc atcagaaact tttactggtt tgatcccagc ttgctcattc
     1921 acttcatcga tctcagaacc tttttgattg atcgtgattt tatcaccaag ttcttttact
     1981 cgatcgaagg caggtttcaa tgctgattct ttgccttcat catacacacg gatacgaacg
     2041 taagtcccta acaagaactg ttcatcagaa tatggatctt tcaatatctt ggtagctgct
     2101 gaactttcag tggttgtttt atttgctgag ttgctgcagc cagttagcac cataaaagag
     2161 atgcccagtg tgattaagga aaatagtagt tttttccgca tctttttcct ctcttcattt
     2221 tgaaaggtga gacgactgcc taatctggct atcgtcccac cctccaactt ttattagtat
     2281 gattatgtga ttatttttct gttacgatat tatctacttc gattgtttga gtgtcgcctt
     2341 tttcagctgc attcactaat tgttgtgcgt acatgatgaa tgaatgtgag ctgtgtgtag
     2401 cacctgtaac aacttctaca ttagcaggtg agccatcttc ttcgcccatt gctttgacga
     2461 attcgtcgtt cagagtaggg atgtaagttt ttggttctgt accgcttttt gctttcatat
     2521 tttcattata ttctgtatca tcttgttttg atttaccgtc tttgtcgata taatcaaagt
     2581 ttgattcagt tactttgccg ccagcaactg tcatttcgaa ttgcacacgg tagccgttag
     2641 agtagttctt ttcttcaagc ttgtaagtgc cgtctttcaa atcagcacca ttgtcgattt
     2701 cgattgtatc tgtgttacca gcttgagcag cttggatcaa ttgttgtgcg tagttttgga
     2761 agctttcaga tgagtgagta gctccagtta cgacttccac accgcttgcg ctttgtgctt
     2821 ttaagaattg gtcattcaac tcaggaatgt atttttctgg gtttgtgcca gattttgctt
     2881 ccatgttttt gttgtattct gcatcttttg tttttgattc gccgttttca ttgacgttat
     2941 catattttga ttcagtgatt ttgccgtctt ttacaaccat ttcaaagact gcacggtaac
     3001 catttgaata atttttttct tctaatttat atgtgccgtc ttgcaaatct ccgccagcta
     3061 caacttttgc agatgattct gttgtgcttt ttgcagtcga agattgtgct gtagatgatt
     3121 cagaagaaga gtttgagctt ccgttgtcat ctgcgccgca agcgcctaac actagagctg
     3181 aaaatgctaa tacggcaaat ccagttacaa aacgtttttt cttcatttta ataccccacc
     3241 attccatttc tagtccacaa tttttctttg tgattcatta tacattctaa tctttttagc
     3301 ctataagtca actatttttg ataaataacc catgtaatat ttcaaacgtt ttctttcagc
     3361 aaatttcgtg aaaaaacgct ttattttaaa atttgaaaaa aatccaaaag gagttagaca
     3421 aaagaacaga acatctatat aatatatgga gattgtgtaa taagtatcaa actaaaagaa
     3481 ttatcatata ttcattatat agatagtcta taaggagcgg atgatcaatg gcaaagcaaa
     3541 atattgtcgt tgtaggagca ggatatgccg gtgtttcagc tacaaaatac ttggcaaaga
     3601 aactgaaaaa agaagatgta gcaattactc tgatcgatcg tcattcgtac catactatga
     3661 tgaccgagtt gcatgaagta gctggcggac gtgtagaacc agaagcaatc caatacgatc
     3721 tgcagcattt gtttgctcgt caaaagaatg tacaacttgt cacagacact gtaatcggta
     3781 tcgataaaga acgaaaaatc gtcaagacca aattaggttc ctatcctttt gatcagctga
     3841 tccttggaat gggcggagag ccgaatgact ttggtacacc tggtgtcaaa gcacacggat
     3901 tcaccctttg gtcatttgaa gattctgtaa ggattcggga acatattgag aagacagtag
     3961 caaaagctgc attggaacca gatgatgaac tgcgtaaagc catgctgact ttcgttgtct
     4021 gtggttctgg atttaccggt attgaaatga ttggggaact gatcgactgg aaaaatcgcc
     4081 tagccaaaga ttataaatta gatccaaacg aaatcacact gatggtcgta gaggcaatgc
     4141 cgacgatctt gaatatgttg gatcgaaatg atgctgcaaa agctgaacgc tatttgcgta
     4201 agcacaacgt ggaattatta ttgaatgcac caatcgtaga agtggctgct gatcatatca
     4261 aattgaaaga cggacgcaac attccgactc acacactgat ttggacagct ggtgtcaaag
     4321 gaacttctga cgctgctgac tttggattag aatcagcacg cggacagcgg ttgatcgcca
     4381 atgaatatat gcaggcaaaa ggctacgaag ataaaaacat ctatatcatt ggtgatttag
     4441 tcttttatga agaattccca ggaacaccga caccgcagat cgttcaagct gctgaacaaa
     4501 caggacacac agccgcagcg aatatcgtgg cttcgatcaa aggcggagaa aagcataaat
     4561 ttaaaggaaa ctatcaagga tttatggttt ctattggtgc caaatggggg gtagctaacc
     4621 tatttgataa gatccattta agcggatttt tagctatcgt aatgaaacat atcgtgaatt
     4681 tgaaatactt ctttgatatt cgttctggtt attatatgtt ccaatattta atgcatgagt
     4741 ttttccatat caaagatgat cgcaacgtga ctcgaggaca ttcttctcgt tacggcaatg
     4801 tcttatggag tgtgccactt cgtattttct atggtttagt ttggttcgtt gaagcttcca
     4861 aaaaaatcat tgggaatggt gaagtgttca aaccaagtac ttggtttggt gaaggatcat
     4921 ggttcactgg aaacagtgtg ttcccttgga catgggaata caatgtaaca gatgttgcca
     4981 gtggtgcttc tgctgctggt gatgcaacca cagctgccag cggagcaggg gcaagtgccg
     5041 gagaagcagc gactcaagct gcacattttg gtttgagtta tgcatacggt gaagaaccaa
     5101 tggctgtgat tgagaagtca ccagactggt tcacaaagat catgcaagtg atcatgccaa
     5161 acaatgatgt agcaatgttc ttccaaaaat tcatggtatt ctttgaaatt gccttggcat
     5221 tagcattgat tgctggatta ttcacatggc tatgcagtgc gacaacgatt gtattggtga
     5281 tcacgttctg cttatcaggc atgttttact gggtaaacat ttggttcatt tttgttgctt
     5341 tcgcattgat gaacggttcc ggacgtgcga ttgggttgga tcgctgggta attccatggc
     5401 tacaacgtac actaggtaat tggtggtacg gtagaccaag ttcccagtac ggcaagaaat
     5461 aaatagataa agaacgttat ttgaatgcaa gatttcaata gaaaggggct gagacaaacc
     5521 gtcacagcct cctttttatg taaaattaaa ggaataagat gcccgagata agcctccatg
     5581 agcaagacac aggtgtcaca acctctgtta caacctcttg ttataaacgg tgttccagaa
     5641 gtagcttctt cgaaaaataa gccgaaattt cacaaaaact tgaaaagtaa ttttcgtaaa
     5701 ttccttctta tttcttgaag ttgcccactt ctgtcacaac ctcttgttat aaacggtgtt
     5761 ccacctgctg cttctcggta ataagcccaa agaattagaa aacatggaaa gctgttttct
     5821 attcttcgtt cttattactc aaagcaagac acaggtgtca caacctcttg tttttatgct
     5881 aaaattgggt gagttaatct ggaaaaagga gaacaaaaat gagccttaaa gaatttgctg
     5941 aaaaaagtct gctcaaacct tgggatgttt ttattatttt gcttttgact gttctttctt
     6001 ttttaccagt catgattttt ggtcttcagc aaaacaccgc aacagcagaa aaagaagcgg
     6061 tactgcgtgt ggatggcaca gaaatcaaaa cattcccttt gatggctgga gaagagagca
     6121 acacatatac ttacaaagat gaacacggag attataactt gatcgagata gatggcgatc
     6181 gagtacggat aaaagaagca gattgcgatg accagatctg cgtacgtcga ggctgggcaa
     6241 cgaaaaatgg cgaaaccatc gtctgtttgc cacataaatt agtgatcgaa gtccgttcaa
     6301 cagatggagg tgacgaagac agtctgattt attagacctt tacacaccat gagtaaatta
     6361 caaaaaatga tttatatttc gctacttgtt gcacaaggag tgatcattgg tttattggaa
     6421 aatatgatcc cttatccttt ttcttttgcg cctggtgcaa aactaggctt agccaatcta
     6481 atcacgatcg ttgccatttt taccatgaaa aaacaagaca gcttcttact actttggcta
     6541 cgactattcc tgactacttt gctaggcgga acgatttcca cattccttta tagtatgagt
     6601 ggtgctttgc ttagttattt tggaatgtta ttggtcaagc aattaggacc aaaacgtgtc
     6661 agtatcatcg gaattagtgc ggccggcggt ttcatgcata atgtcggaca gcttttgatg
     6721 gcttctttca ttgcacaatc atggacagtc atgttgtact tgccagtcct ttcagtttta
     6781 gggattttat cagggattgc aatcgggatc gcagcgaatt atcttttacg acatgtgcag
     6841 acacttcaac gattccaaaa agattatgag cagggaacca aacaaaaatg gagcccaatg
     6901 tttaccaaaa aataatcgtc acacaaggag tttttttatg aagctacatc caatgtggga
     6961 aaactatcct gctttaagta aagaattgac agaaacacta aaacggatgg aagaaactgt
     7021 ccgcctgaaa aacaaacctg tcgaacaagc aatcaaagaa acgatccatg ccggcggaaa
     7081 gctgttgcgt cctgcctatc agctattgtt ctcacaattt ggaccagagc aagatcgaga
     7141 caaagccatc gctttggcag cttctatcga aatgctccat acggccacac tgatccatga
     7201 tgatatcgtt gatgaagcgg atctgcgacg tggtcagcct aatatccgta gtcagtttgg
     7261 taatgtcgtt tctgtctatg caggagacta tttatttgtc tgctgtttta aactattgtc
     7321 tgattactcc acttccttga aaagtctcca attgaattct cgcagtatgg aaaaagtatt
     7381 gaatggcgaa ttagggcaga tggatgatcg ctataattat gaactttctg taaaagaata
     7441 tttggaaaat atttcaggta agacagctga actgttccaa ttaagttgtt ctgttggcgc
     7501 ttttgaaagt ggaacaagcg agcgcttcgc aaaaaaagca ggagatatcg gactttctat
     7561 cgggatggcc tttcagatta tcgatgatat tttagattat acaaaagaga gccaggaaat
     7621 cggcaaacct gtactagaag acatgcgtca aggggtctat tctttaccgt tgatctactc
     7681 tttgcaaaaa aacaaaccaa agctactacc ttatttagag aagaaagcgg caatgacaga
     7741 agaagatgtc gacgccgtac gcaaaatcgt tgaacataca ggaggcgtgg aagaagctag
     7801 gaagttagcg gcctcttaca cagaaaaggc tttgaaggaa ataaagaaat tacctgccac
     7861 ctctcttcga acaaaagaga atctcttttc ccttacccaa ctgattttgg atcgcaaaga
     7921 ctgaataggg aaaggttcga tacgtaaata aatttctcag aaggaaatct acgtgttttt
     7981 tgacaaattg aattgtagtt cttgtattta tgataaaaag caaaaataaa gagcaacgtc
     8041 cgttagcgac gttgctcttt tttatcttga atattttttt accttttcga tttcttataa
     8101 ctcataaaag tgattcttaa accgattaca agtaatataa cgcctgcgag tgttatccaa
     8161 ttattcgatt gacttccagt tttaggaagt gctctttttg atttgtttcc attgtcattg
     8221 cttgttttat tagttaagtt aaagttcgtc ctgttatccg aacttgtttt tgagaaggag
     8281 acacttgcat gacgtgtatc gcttgtggta gacgacgtgt ctgtactatc gcttgaagtt
     8341 gatgaatctg agctatcact tgtggtagag gatgtatctg tactgtcact tgaagctgac
     8401 gtgtccgtgc tatcacttgt agtggtagat gaatctgagc tatcacttgt ggtagaggta
     8461 gtatctgtac tgtcacttga agctgacgtg tccgtgctat cacttgtggt agaggtagta
     8521 tctgtactgt cacttgaagc tgatgtgtcc gtgctatcac ttgtggtaga ggtagtatct
     8581 gtactgtcgc ttgaagctg
//
LOCUS       DACCVZ010000110         8493 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.113, whole genome shotgun sequence.
ACCESSION   DACCVZ010000110 DACCVZ010000000
VERSION     DACCVZ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.113"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..173)
                     /locus_tag="IVW63_002578"
     CDS             complement(<1..173)
                     /locus_tag="IVW63_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009325336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7860815.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="IVW63_002579"
     CDS             complement(593..1714)
                     /locus_tag="IVW63_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HAP7860816.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /locus_tag="IVW63_002580"
     CDS             2042..3451
                     /locus_tag="IVW63_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HAP7860817.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /locus_tag="IVW63_002581"
     CDS             3448..4176
                     /locus_tag="IVW63_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP7860818.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="IVW63_002582"
     CDS             complement(4304..5215)
                     /locus_tag="IVW63_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP7860819.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="IVW63_002583"
     CDS             complement(5232..6239)
                     /locus_tag="IVW63_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAP7860820.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="IVW63_002584"
     CDS             complement(6236..8365)
                     /locus_tag="IVW63_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP7860821.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..8477)
                     /locus_tag="IVW63_002585"
     CDS             complement(8370..8477)
                     /locus_tag="IVW63_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860822.1"
                     /translation="MQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1728 c         1486 g         2680 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg ttt
//
LOCUS       DACCVZ010000111         7793 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.114, whole genome shotgun sequence.
ACCESSION   DACCVZ010000111 DACCVZ010000000
VERSION     DACCVZ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7793
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.114"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..148
                     /locus_tag="IVW63_002586"
     CDS             <1..148
                     /locus_tag="IVW63_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP7860823.1"
                     /translation="EKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRY
                     SLGY"
     gene            complement(303..746)
                     /locus_tag="IVW63_002587"
     CDS             complement(303..746)
                     /locus_tag="IVW63_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860824.1"
                     /translation="MEAYEFLGAALRNIFGNLLSACLVAEYLVKRKIVRFNNIFVIMA
                     SIVGIGFAGISKIIGGLMESINDIFAFFGYGAIAILMYQVIPFRKIMPRISRYSYDIY
                     LLHILVFSTIHQIIPNLVLAAFVSIPITLVLSYYYSIMLYRLKLK"
     gene            complement(834..1199)
                     /locus_tag="IVW63_002588"
     CDS             complement(834..1199)
                     /locus_tag="IVW63_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HAP7860825.1"
                     /translation="MYYFQQSYLPAILNKAISIGDTGVHIFFFCSGFGLYLSYLKKPI
                     TLGEFLQKRFIKIYIPYIIVITVSVLLPYMTQDLNAAKVYLSHVLLFKIFLPVYEESL
                     GPFGLFRQLFSSISYSYQL"
     gene            complement(1543..3195)
                     /locus_tag="IVW63_002589"
     CDS             complement(1543..3195)
                     /locus_tag="IVW63_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAP7860826.1"
                     /translation="MDHNANYYHWLTNANAEIVEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLSDYLNKTYETPSVVVGYDSRIKSDVFAKVAADIF
                     AANGIQVHLWPELLPVPTVSFAIRYLKASAGVMITASHNPSKYNGYKVYGAGGCQITT
                     EAAAEILAEIEKLDIFADVKMGGDASRIASIQPEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEINEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKNAEGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PTDPVMVKTIVTMDLGERIASNYGVRTVDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLFDKLNEIYAKYGYCLNTLHSF
                     EFEGAAGFTKMQKIMVEFHKGLDMIGGKKVIETLDYSTGLNGLPKSDVLKYLLEGNCS
                     VVVRPSGTEPKLKTYISVSAESKEAAEVMEAVMAAELAEMFK"
     gene            complement(3255..3834)
                     /locus_tag="IVW63_002590"
                     /pseudo
     CDS             complement(3255..3834)
                     /locus_tag="IVW63_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612938.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
     gene            complement(5066..5782)
                     /locus_tag="IVW63_002591"
     CDS             complement(5066..5782)
                     /locus_tag="IVW63_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860827.1"
                     /translation="MTVIITMAGLGSRFRKVGYTVPKFMIEAKGKTLFDWSLDSLLDY
                     NSHVEKYVFVVRKEDDATVFIKEHCSLYGIENVEVVEIDYMTDGQATTCMLAIPYCAP
                     DNAIMVYNIDTYVEPGEMKYVDISGEGHIPCFHADGDHWSFAKLNEYGDVVEVREKVR
                     ISNNCTLGAYYFSSAKLYASLYEEYYADERHLEKNEKYIAPLYNYMIEKGMKVTISIV
                     DKSKVHVLGTPEELDVFLNE"
     gene            complement(5807..6205)
                     /locus_tag="IVW63_002592"
     CDS             complement(5807..6205)
                     /locus_tag="IVW63_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HAP7860828.1"
                     /translation="MFKDYAFVFDIDGTLCPIKKKDEKYEDLVPYANMVEKLRYYKEN
                     GAKITLFTSRNMNSYHGNLGVINANTAKILLAWLDKWEIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLSCTLDQLDEICKKSKLKSE"
     gene            complement(6293..>7793)
                     /locus_tag="IVW63_002593"
     CDS             complement(6293..>7793)
                     /locus_tag="IVW63_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HAP7860829.1"
                     /translation="IDIACYEKMDKVARRLDKYIKSKTVNIIQLKELGDLGRTIYDSL
                     IGCDEPVIINFADTIINDNIYSLECDSFFYAEDYYSNTWTFFEEKDGDIISVLDKNEL
                     KEDDGKKHKLFSGVFQIMDAQYFRECLRKALMSNVVNVNSFYQALQEYSKRYEFLSIK
                     TNNWFDIGHADKYYNSKLEVKAREFNHISIDKDRSILRKISEDVEKFIGEIKWYLKLP
                     AQVEYVRPRIFEYSTSYINPYVSMEYYSYHTVHELFLYSDLTKKQWIDIFNRIRFVCS
                     DFKRYSVSGDNIQKSLKDMYLDKTFQRFNKLRKDPRFTEFFSSDIQINGVRYKSLDQI
                     EALLSVSVPRELFDITQFNIIHGDLCFANIMVDNTFSFIKVIDPRGKFGDFDIYGDYR
                     YELAKLFHSVDGKYDFIIKDLFTIKYDPKKAIIDYIVQDRKRDYDLYEVFYSVFKDEI
                     GSDLKKIELIEALLFLSMIPLHGESLNHQMAMLATGLEILGRVVPDIYC"
BASE COUNT         2615 a         1655 c         1153 g         2370 t
ORIGIN      
        1 agaaaaatta ggttgtcaaa atttcaactc acgttctgtt aaagggctag agagtagatt
       61 tgaaagcata ttactggctt acagtgttct attaagtcga gcacaacgac gttttgaagg
      121 aactttgaga tattctttag gatattaaaa ttaactagca ccacgggtgt aatcatttag
      181 ttttatctcc tttttaccaa ccatctacca ctaggttacg aactacctaa gtgcccacca
      241 tccgccgcgt ggaggctgtt aatcaggatg gcaaccgccc ggtagaggcg acaattatgc
      301 tatcatttta atttaagtct atataacata atactataat aatatgacaa caccaacgtt
      361 ataggaatgg aaacaaatgc cgccaaaacc aagttaggga taatttgatg aatcgtacta
      421 aatacaagaa tatggagtag atatatatca tatgagtatc ttgaaatcct aggcattatc
      481 tttctaaatg gaataacttg atacattaaa attgcaattg caccgtaacc gaagaatgca
      541 aaaatatcat taatagactc catcagtcca ccaataattt tcgatatacc agcaaaacca
      601 attccaacaa tggacgccat aatcacgaat atattattaa atcttactat ttttcttttc
      661 actaaatact ctgcaaccaa acatgccgaa agtaaattcc caaatatatt gcgcaaagca
      721 gctcccaaga actcgtatgc ttccatatcc tgtatgaaac atcataatag cccagatact
      781 aataactcag cttgcaacaa gcaatcattt cattcctatt tttctctata gttttacaat
      841 tggtatgaat aagaaataga actgaataat tgtcgaaata aaccaaaggg acccagtgac
      901 tcctcatata ctggtagaaa aattttaaat aacaaaacat gagacaaata tacttttgca
      961 gcatttaaat cttgtgtcat ataaggtagt aacactgata ccgtaattac gataatatac
     1021 ggaatataaa tcttgataaa tcgtttctgt aaaaattcac ccaatgtaat aggctttttt
     1081 aaatatgaca gatatagccc aaaacctgag caaaagaaga atatatgcac tcctgtatca
     1141 ccaatagata ttgctttgtt cagtattgct ggcaaatacg attgctgaaa atagtacatc
     1201 aatacaatag cgaatattga aaacgccttc tcaaaactaa taatatcacg tttatttctt
     1261 tccccctcat tttattattt caatagtttt attcatattc tactcctttc atctctattg
     1321 ctgaatacat tattaaaact ctaatatctc ttatttctcc cttactgctt tgatcggtgc
     1381 ttcatcaggc tgctgtgtct ctgttaacac ttctttgcct tttcgatcca cacagtcggc
     1441 ccctttacct caattatgta aacagaaccg taaagcagga aatttttatt aaacatagat
     1501 gttgctactt cggacattga cactcagatc tttttcatag tattacttaa acatttcagc
     1561 cagttcagca gccataacag cttccattac ttcggcagct tccttgcttt ctgcgctaac
     1621 gctgatatag gtcttcagct tcggctcagt gccggaaggc cgaaccacta cagagcagtt
     1681 gccctccagc agatatttga gaacatcaga cttcggcagg ccattcagtc ccgtgctgta
     1741 atccaaggtt tcgatgacct tcttacctcc aatcatatca agacctttat ggaattcaac
     1801 cataattttc tgcatcttgg taaaacctgc cgcaccctca aactcaaagg aatgcagggt
     1861 gttcaaacag tagccatact tagcataaat ctcgttcagc ttatcaaaca gactgatacc
     1921 ctgagtcttg tagtaagaga acatctcgca gatcagataa gcggcgttga caccatcctt
     1981 gtcacggaca tagctgccgg atagatagcc gtaggattcc tcaaagccga aaatatagct
     2041 gtccaccttg cctgcctttt ccagcatacc aatctgttcg ccgatgaact tgaagccggt
     2101 caacacatcg acagtacgca cgccatagtt ggaagcgatc cgctcgccca gatccatagt
     2161 cacgatggtc ttgaccatca cagggtcagt gggcatcttg ccgtgcttaa ttctctgaga
     2221 gcatatgtag tccagaagca acagaccagt ttcgttaccg gacagcagga cataatcccc
     2281 ttctgcattc ttcacggcga tacccacacg gtcgcagtca gggtcggtag ccagcagcag
     2341 atcagcatta tacttcttgg catactccat gcccagagac atagcttcat taatttccgg
     2401 attcggataa ggacaggtcg ggaaattacc gtctggcaga cgctgctctt cgacaacggt
     2461 cacattgctg tagcccattt ctgccagagt acgggtaaca ggcaccagac cggtaccatt
     2521 caaaggagaa tacacgatag caacattctt gtccacttct tcgccaaaca gaaccgactg
     2581 gccctttact tcttcaatga aagcagtcag aacctctggc tggatagaag cgattctgga
     2641 agcgtcgccg cccattttca catctgcaaa aatatccagc ttttcaattt cagccagaat
     2701 ctcagcggca gcctcggtgg tgatctggca gccgcctgcg ccatagacct tatatccgtt
     2761 atacttggaa ggattatggg atgcggtgat cataacaccg gcagaagcct tcagataacg
     2821 gatagcaaag gatacggtag gcacaggcag cagctccggc cacagatgca cctgaatacc
     2881 gtttgcagca aagatgtccg cggcaacctt tgcaaataca tcggacttga ttcgggaatc
     2941 atagcccacg acgacagaag gggtttcata ggtcttattc agatagtctg acagtccctg
     3001 gcttgcctta cctacggtgt gtacgttcat acgattagtg cctgcaccaa tggtgccacg
     3061 cagaccaccg gtaccaaagg acagattttt atagaaggag tcctcaatgt ccttctcgga
     3121 atatgaccgc agttcctcta caatttctgc attggcattt gtaagccaat gataataatt
     3181 tgcattatga tccatagaat ctctccaatc ttttaaaatt ctgctcattt atttttaagg
     3241 ttaggatgaa tatatcagct caaataatat ataaccccac taatgccgcc acccaaagta
     3301 ttataaaata aatctgacaa ttggaatgtc tctatgtgta aaaataactg caaaaactct
     3361 ataagacacg aacataaaaa aacaaatttt ataatctctg ataaattttt ccaaaatctt
     3421 tttctgaagc cttataccac attactagaa ttataaatgg aataaacaga ataacatttt
     3481 caaaacattc tgtagttaat ctaatctccc ctgtcgtttc attcacagag taaatccacc
     3541 aactaccaaa cacattagac aaaggattta gccaaacata tctatccatc agtgttctaa
     3601 aaagaatcat atttgtaaaa aacacaagca aaaacatttt tctaaatgag cttgattttc
     3661 tgaaataccg aatccagaca agaaaagatt ttttcaaacc taatcctgat ttctcctcag
     3721 ccatcgcaaa caagtataaa aacatagcca aaactgcaat taaaatcgaa acccaaatat
     3781 ttgatacaat gcagataaca cattaaccaa aatagaagat atgattttct tcataaactc
     3841 tcctttcatc atgcgctaaa tgagtaccat caagaaggtt tcgtaaaagg aggtacccac
     3901 tctaacatga ataacctcgg ccagcgaaaa taaaactcaa cagaattcct atctctatgc
     3961 tgctataatt tcaacaaatt tacatgtacc agttactaat ctaatataat tttttcagca
     4021 aggtaaattt cacactacac gcatacacaa aaactgtaga aattaaaatt attatcattc
     4081 cacaagtcat ttctattaat gaatttgtaa tccccaattt tgggaaaata aaatttaaag
     4141 cagctattat atacggatgt aaacaaaata ataacgtact aattcttcgc agatgtactg
     4201 ttatttttat aaatgtacta tctttaggct cagtgatact gatacaacta ccagtgctaa
     4261 tggaatggaa aatattaaca aattattgac ttctcgcaaa gctatttgat ttatgatgaa
     4321 actttcacca actaataagc atcctatagc taaaacagca cataagataa aattacggta
     4381 tttaaagacc ttattaagta tagtgttttt gtggaaggct aagtgttgcc caataatgac
     4441 gcatggtaca cctataaata atccattacg agttgttaca aacacgcttt tataacaata
     4501 tctaatatac tcgatggaat cattcccaga taatataaac caataagatt caaatgctaa
     4561 acctactacg catagcaaca aaccactgag aaactttatt ttagaaacct ggcttttgcg
     4621 tactaaccat agagcaaaag ccagtgcagg caagaaccac aggtgatagt aactaccaat
     4681 aaacagaaaa tctctgatat acaataatac atctgttttc cagctaaaat ctgactgtac
     4741 ccaattcttt aatactaatg gaatatataa tatagaccaa ataatgtaaa ttttaagtac
     4801 tctgtagatt tgtttagata atttagcgga tgtaacttca ccactacaca acaaaaagga
     4861 actgatgatg aaaaaagtag gaacggcaac cgtactcagt cctgcaacaa taccaatact
     4921 aaatgcttaa tctggagcta aatagttttg acctaaatga cgaacaacaa ctaaaatagc
     4981 cattagtatt tttagaatat ctatcgaata gtactccccc acacacgcag ctttataatt
     5041 aacattttct atgattatat tttccctatt catttaagaa cacatcgagc tcttctggag
     5101 taccgagtac gtgaactttt gatttatcta ctatactaat ggttaccttc atgcccttct
     5161 ctatcatata attatatagc ggcgcaatat atttctcatt cttttccaga tgcctttcat
     5221 ctgcataata ttcttcgtag agtgatgcat ataattttgc agaagaaaaa taatatgcac
     5281 ctaaagtaca attgttagaa attctaactt tttctcttac ttctactaca tcaccatatt
     5341 cgttcaactt ggcaaaactc caatgatcac cgtccgcatg gaaacacgga atatgtcctt
     5401 ctccagaaat atcaacgtat ttcatctcac ctggctcaac atatgtatct atgttataaa
     5461 ccataattgc attatcaggt gcgcaataag gaattgcaag catacatgta gtggcttgtc
     5521 catcagtcat atagtcaatt tcaactacct cgacattttc aattccatac agactgcaat
     5581 gttctttgat aaaaacagta gcatcatctt ccttacgcac aacaaaaaca tacttttcta
     5641 catgtgaatt ataatcaagc aagctgtcta aggaccaatc aaataaggtt ttaccttttg
     5701 cttcaatcat aaatttgggc acagtgtagc caactttacg aaagcgactg ccaagaccag
     5761 ccattgtaat aataaccgtc atcttattca ctttataaag tctcctttac tcagatttca
     5821 atttggattt tttgcaaatc tcatcgagct gatccagggt acacgataaa aattcatccg
     5881 gacgaactgt gcgatcatca acataaaacc ctttatggcc tggccaaggc tttccataaa
     5941 gaatttcatc atacggaatc tcccacttat ctagccaagc caacaagatt tttgcagtat
     6001 ttgcattgat cacacctaaa ttaccatgat aagaattcat attgcgagat gtgaacagtg
     6061 taatctttgc tccgttctcc ttatagtatc gcaacttctc caccatatta gcatacggaa
     6121 ctaaatcttc atatttctca tctttctttt tgatggggca caaagttcca tcaatatcaa
     6181 aaacaaatgc gtaatcttta aacatataac taagacatct cctttatttt agccaggcaa
     6241 tttatatgcc cggctttaca ctgatcaaat agaaaaacaa tagctcaaag cattaacaat
     6301 aaatatccgg gacaactcgt cctaaaattt ccaaaccagt tgctaacata gccatctgat
     6361 ggtttaagct ttctccatgc aaaggaatca tacttaaaaa cagcaaagcc tcaataagtt
     6421 caattttttt caaatcagaa cctatttcat ctttgaagac agagtaaaat acttcatata
     6481 aatcataatc tcgtttacga tcttgaacaa tatagtctat gattgccttc tttggatcat
     6541 attttattgt aaacaagtcc ttaattataa agtcatattt tccatcaaca ctatgaaaca
     6601 attttgccag ttcatatcta taatcaccat aaatatcaaa atctccaaac ttacctcgcg
     6661 gatctatgac tttaatgaac gaaaatgtgt tatctaccat aatattggca aagcataagt
     6721 caccatgaat aatattaaat tgcgtaatgt caaacaattc tcttggaaca cttacgctca
     6781 ataaagcttc tatctggtcc aaagatttat atctgactcc atttatttga atatcagaag
     6841 aaaagaattc tgtgaaccgg gggtcctttc tgagcttatt gaatctctga aatgttttat
     6901 cgagatacat atctttcaat gacttttgaa tattatcccc tgaaacagag tatctcttaa
     6961 agtctgagca tacaaatcgt attctattaa agatatctat ccattgtttt tttgttaagt
     7021 cactatagag aaataactcg tgaacagtat gatacgaata gtattccata cttacatatg
     7081 gattaatata cgaagtagaa tattcgaata ttctaggtct cacatattct acctgtgctg
     7141 gcaacttaag ataccactta atttctccga taaatttttc aacatcttca ctaatttttc
     7201 tcaggatgct acgatcttta tcaattgaaa tgtggttaaa ttctcttgcc ttaacttcca
     7261 atttggaatt ataatattta tctgcatgtc caatgtcaaa ccaattattt gttttaatag
     7321 agagaaattc atatcgtttg ctatactctt gtaaagcttg ataaaaacta ttcacattta
     7381 ctacatttga catcaaagct ttacgcaaac actctctaaa atactgggca tccataattt
     7441 gaaatacacc agaaaacagt ttgtgcttct ttccatcatc ttcttttaac tcgttcttat
     7501 ctaaaacaga aataatatct ccgtcttttt cttcaaagaa tgtccaagta ttactataat
     7561 agtcttcagc atagaaaaag ctgtcacatt ccaaggaata tatattatca ttgataatgg
     7621 tatcagcaaa attaataata acaggctcgt cacatcctat tagagaatca tatatagttc
     7681 ttccaagatc ccctaactct ttaagctgaa taatatttac tgttttagat ttaatatact
     7741 tatctaatcg tcttgctacc ttatccatct tttcgtaaca ggcaatatcg ata
//
LOCUS       DACCVZ010000112         7695 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.115, whole genome shotgun sequence.
ACCESSION   DACCVZ010000112 DACCVZ010000000
VERSION     DACCVZ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.115"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            110..577
                     /locus_tag="IVW63_002594"
     CDS             110..577
                     /locus_tag="IVW63_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAP7860830.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            584..3076
                     /locus_tag="IVW63_002595"
     CDS             584..3076
                     /locus_tag="IVW63_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAP7860831.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            3297..4220
                     /locus_tag="IVW63_002596"
     CDS             3297..4220
                     /locus_tag="IVW63_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAP7860832.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFFKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            4238..5479
                     /locus_tag="IVW63_002597"
     CDS             4238..5479
                     /locus_tag="IVW63_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAP7860833.1"
                     /translation="MTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAYGLRS
                     RAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISAVIVS
                     DPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVAEIRK
                     NTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFGQERN
                     SLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNVYKAA
                     VDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVYKFVG
                     EVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRAPNPM
                     MILTMPVAQPVKPGDMIRKRK"
     gene            5613..6959
                     /gene="gor"
                     /locus_tag="IVW63_002598"
     CDS             5613..6959
                     /gene="gor"
                     /locus_tag="IVW63_002598"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAP7860834.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
BASE COUNT         2669 a         1242 c         1660 g         2124 t
ORIGIN      
        1 ttttttttgt tgattctaaa ggatttattt aacaaaaagc gttcttcttt ctttctatta
       61 tcaaattcgt tataattaag gtcaatatta gtcaaaggga atgaataaga tggcacatca
      121 gaatacctcg gatttaattg aatcatatat aaagaaaatt ctggaaaata gtgaaatgat
      181 cgagattcga aggattgaaa tggcagacct ctttaactgt gttccttcac aaatcaacta
      241 tgtgattaat acccgtttta ccatccaacg tggttatcta gtagaaagca aacgtggtgg
      301 tggtggttat atacgaattg caaaagtaag gatttcagat aaaaaacaat tacttgagca
      361 gataaatcag ttatttgatg atacaatcag tgagaaaaat gcttttgcta ttattcaaaa
      421 actttatgaa gaccaaataa ttacaaaaaa agaaggaaac ttgatgttga gtgcaattgc
      481 aaaaaacaca ttgaatttca atgaatatga agatcataca cgtgctcgga ttctccgagc
      541 atttctggaa cgtttaagtt atgaagatgg gaagtgagat tagatggaag aactttttac
      601 tgaaagagcc caagcagtat tagaaattgc acaagaagaa gcaaaacggt tgaaacatca
      661 atcagttagt tcagaacatg ttttactagc cttagtggtc gagcaaaatg gaattgctgg
      721 aaaagtatta cgtgaaatgg atttgaatga aacggaaatt tatgaagaaa ttgaacatct
      781 gattggttat ggtggtatcc gttcttaccc taaaggagtc tttcttccat attcaccaag
      841 aatgaaacaa gtttttgctt tagctagcag cgaagtgaag aaaactggtt ctcaaaaagt
      901 tggaacagaa catattttga tgagcttatt aaaagatgaa agtatcatgg ctactcgaat
      961 catgatcaac ttaggtatca gcctttcaaa agcccgtcaa gttctgaaac aaaaaatggg
     1021 gctagctggt gattctgctg gaaaaggaat gaatcgtcgt agaaatgtaa atgtacaaga
     1081 taaacggcaa acaccgcaag gaacacctac gctagattca ttagcacgtg atttgacgaa
     1141 attagcaaaa gaaaacaagc tggacccagt tgttggtcgt tcgagagaag tgaaacggct
     1201 tatccagatt cttagccgac ggacaaagaa taaccctgta ctggtgggtg aacctggtgt
     1261 aggcaaaaca gccattgctg aagggttagc tcaaaaaatc attttaggtg aagtgccaga
     1321 agacatgcaa gaaaagcgcc tgatgatgct tgatatggga tctttggttg ctggtacgaa
     1381 atatcgcggt gaatttgaag atcgaatgaa aaaggtcatc gacgaaatct ataatgatgg
     1441 tcaagtaatc ttattcattg atgaattgca taccttaatt ggtgcaggtg gagcagaagg
     1501 agcaattgat gcttcgaata tcttgaaacc ggcgttagct cgaggagaat tacaaacgat
     1561 cggagcaacg accctagatg aatatcaaaa atatatcgaa aaagattctg cattagagcg
     1621 acgttttgct cgcattcaag tagatgagcc aactcctgaa gaagcagaag tgattcttca
     1681 aggattacgt acaagatatg aagagcacca tggagtggag atcacagatg aagctgtacg
     1741 agcagcagtc aatctttctg ttcgttatat cacttctcgt caactacccg ataaagcaat
     1801 tgatttgatc gatgaatcag cagcgaaagt ccgtttggat caaaccgatc acttaacaaa
     1861 atcaactgtg atcaaactag aaatcgatga actagtacaa gaaaaggaag cagcgatcca
     1921 aaaacaagac tttgaaaatg ctgctcaatt acgcagacaa gaaaaagcac tacgtaaaaa
     1981 gctgcaaaaa gtttctgcaa ttgaagcaaa acaggagcaa ggttattctg atcgtgtaac
     2041 agaagaagat gttgctacag ttgtatcgga gtggactggt gtccctctac agcagttgga
     2101 gaaaaaagaa agcgaacgct tgttagaact ggaaggactt ctgcatgaac gtgtcgttgg
     2161 tcaagatgag gctgtcaaag cagtttcacg tgcgatccgc cgtgcacgaa gcggattgaa
     2221 agatcctgat cgtccaattg gttcattcat gttccttgga ccaactggtg tcggaaaaac
     2281 agaattggcc aaagcacttt cagaagtcat gtttggaagt gaagatgccc tgatccgtgt
     2341 tgatatgtca gaatttatgg aaaaatacag tacaagccga ttaatcgggt ctcctccagg
     2401 atacgtaggg tatgatgaag gtggacagtt gacagaaaaa attcgtcaaa aaccatattc
     2461 agtgattctc ttagatgaag tggagaaagc acatccagac gttttcaatt tacttctgca
     2521 agtattggat gatggtcatt taacagattc taaaggtaga aaagtggact ttagaaatac
     2581 aatcatgatt atgacttcaa atatcggagc gacacaaatt cgagaagaaa aaaatgtcgg
     2641 attcaatgtc caagatgtta ctaaagatca caaagccatg caaaaacgta tcttagaaga
     2701 gttaaagaaa gctttccgac ctgaattctt gaatcgaatc gatgagactg tcgtcttcca
     2761 ttcattgagt aaagatgaaa tccatacaat cgtccaaatc atgagcaaag cgattatcaa
     2821 acgattgaaa gaacaagata ttcaagtgaa aatcacacca tctgcaatcg atgtgatcgg
     2881 gaaagctgga tttgatcctg aatatggtgc acgtccaatc cgtcgcgcac ttcaaaaaga
     2941 aattgaagat cgattgagcg aggctttgct tggcggagaa attcgtttag gtgaccacgt
     3001 aacagtaggt gcttcaaaag gtaagatcac attgaatgtt cgcggaccta aaaaggaaac
     3061 agtaggttcc ctatagttac ttggcctgtg tagctgaatt tttataatag taagacttga
     3121 ttaagaggtt gtgacaagat ttttgtcaca atctcttttt atatttggac agaatatatc
     3181 gaactttatt ttgatttttt gtgaaataat tttcaaaaat ccgactttaa atagaagaag
     3241 tattggaaag tttttagagc tatgctacta ttatgaagtt gtaggaggag aaaattatga
     3301 tcgaactcat aaccacagta gaaactattg aacaagcaga acagttgctt gctgcaggtg
     3361 cagatacact atatttcggt gaagagcaat ttggattgcg tctgcctgct tcatttacac
     3421 gagaagaaca gcgacaattg gtagaattag cacacaagta tggtaaaaaa gcgaatattg
     3481 ctgtaaatgg gatcattcat cctgaaaaaa tgaaaaatgt acctgaatat ttggcttttt
     3541 ttaaagaaat aaacgtagat gtgatcacag ttggtgatac aggtattatt tatacgatga
     3601 aaaaaaatcc tgaattgcgt ataccgtata tttatgatgc tgaaacatta gtaacgagcg
     3661 cacgtcaaat caatttctgg gcgaaaaaag gcgcagttgg agcagtactt gctcgtgaag
     3721 ttccttttga agagatgaag gcgatggaag aaaaactcga tattcctgta gaaacccttg
     3781 tgtatggtgc tacatgcatc catcaatcca aacgtccact gctacagaat tactataact
     3841 atacgaaaca agacgaacaa aaagatcgtg aaagaggtct ttttatctcg gaacctaaaa
     3901 aagaagagac acattattct atttatgaag atagtcatgg cacacatatt tttgccagca
     3961 atgatctgaa tctctcgaat gaattgaatg aactttatca gcatcattac tgtacatgga
     4021 aattggacgg attatttact ccaggcgaaa aattcgtaaa catcactcga ctattcgccg
     4081 aagcaaaaaa acaaatttta gaaggtagct gggatcaaga aaaagcggaa aaaatgacta
     4141 gcgaaatcag taaattgcat cctgaaaacc gtgaattaga tacaggattc ttttatattg
     4201 atccttctgc tatcaaataa ggagtatgat gaaagaaatg acagtaaaaa gaaaattgaa
     4261 acgaccagaa atcctagcgc cagcaggaac actggaaaag ttaaaaaccg cgatccatta
     4321 tggagcagat gcagtatata ttggcgggaa tgcatatggt ttaagaagcc gtgcaggtaa
     4381 ttttacttat gaagaaatgg ctgaaggagt tgcttttgca aaagaacatg atgcgaaggt
     4441 atacgttgct gctaatatgg tcacccatga aggaaatgaa gatggagcag gggaattttt
     4501 ccgcagtttg cgtgatgtcg gtatttctgc agtgattgtt tctgatccag ctttgatcga
     4561 aatttgtgcg acagaagccc caggtctgcc gatccattta tccactcaag cttcagcaac
     4621 taattttgag acattggaat tctggaaaga agaagggttg gaacgtgtcg ttttagctcg
     4681 tgaagtttca atggaggaag tggcagagat tcgtaaaaat acggataccg aaatcgaagc
     4741 atttatccat ggtgccatgt gtatctctta ttctggtcga tgcacattgt ccaaccatat
     4801 gtcgatgcgg gatgcaaacc gtggcggatg ttctcaatct tgtcgctgga agtatggatt
     4861 gttcgatatg ccttttggtc aagaacgaaa cagtttaact gatacaggcg aagtggaaga
     4921 agaattctcg atgagtgcag tggatatgtc aatgatcgaa catattccag aattgattga
     4981 aaacggcgta gacagcttca agatcgaagg aagaatgaaa tcgatccatt atgtatctac
     5041 ggtgtcaaat gtctataaag cggctgtaga cagttatatg gaagatcctg aaaactatgt
     5101 ctgcaagcaa gaatggatcg acgagttatg gaaagtagca caacgagaat tagctacagg
     5161 tttttactac aatacaccaa ctgaaaacga acaattattc ggtgaacgtc gtaaaatccc
     5221 agtatataaa tttgtcggtg aagtattatc ttatgatgag gcaacacaga ttgctacgat
     5281 acgtcagaga aacttgtttt ctgtaggaga tgaaatcgaa ttttatggtc caggattcag
     5341 tcatttcagt caaaccgttg aagttatgca taatgaagaa ggcgaatcca ttgaccgagc
     5401 accaaatcca atgatgattt taactatgcc agtcgcacag ccggtgaaac ctggagatat
     5461 gatccgaaaa cgtaaataag gaaaaagctg atatatccct gttttaagca tcttcgcata
     5521 caaaattcaa gaaaagtgtt acacttgttt tctgtagaaa aaggatcgtt aaataaaggt
     5581 tttgattgat ctcttcaata aggaggaaca aaatgcaaat atatgattac atcgtaattg
     5641 gtggcggctc tggcggtatt gcttcagcaa acagagcagg gatgcatggc gcaaaagttt
     5701 tgctgattga agcgaatgaa ttgggcggaa catgtgtcaa cgtcggttgt gtacctaaaa
     5761 aagttatgtg gcaagcaagt acgattttgg aaacaattga acgagatgcc tcaagttacg
     5821 gtatccaagc agatttaaaa aatgttgatt tcgccggtct agtagaaaga cgagaaaaat
     5881 atattgattt tctacacggt gcttatcaaa gaggattaga tagcaatcat gtcgaggcta
     5941 taaaaggtta cgctactttt atcgatagtc aaacgatcga agtaaacggt gaaacctatc
     6001 gtgctcctaa aatcttgatc gctactggag gccgtgcaag taaaatgacc attcctggtg
     6061 gagaatacgc aattgattca aatggatttt ttgaattaac agagttacct aagagagcaa
     6121 tcgttttagg tgctggatac attgcggctg aactttcagg tgtatttcgt ggtttaggta
     6181 gtgaagtcat gtgggcatat cgaaaagaac gaccacttag aacgtttgat aaaatgcttt
     6241 cggacaattt gatccaaatg taccaagaag ctggaataaa aacttacgca catcatattg
     6301 ctaaagaaat tactaaaaac aatgacgaat atacggtgct atttgaaaat ggtgaaacct
     6361 taactggtga ttgtgtactt tttgccggtg gacgtgtacc gaataccgaa aaattaggtc
     6421 tggaaaatac aaatgtggaa ttggacaaaa aagggtttat caaagtagat aaataccaaa
     6481 atacaacgga tgaacatatt tttgctgttg gtgatgtgat cggtaaatta gatctgactc
     6541 ctgttgcaat cgcagctggt agacgtttat cagaacgttt atttaatgga aagaaagatt
     6601 cttatcttga ctataaactt gttccgacag tcgtctttac gcatccacca attgcaacaa
     6661 ttggtttgac agaagaagaa gcattggaaa aatatggcga aaatgaattg aaagtttatc
     6721 gttcacgctt taccccaatg tactttgcat taaatgatta tcgccaaaaa tgcgaaatga
     6781 aattgatctg tgtcggaaaa gaagaaagaa tcgtcggctt acatgctatt ggtgttggtg
     6841 tcgatgagat gctgcaaggt tttgccgtgg ctatcaagat gggtgcaact aaagaagact
     6901 ttgacaatac agtagccatc catccaacag gagcggaaga attcgtaacg atgcgataat
     6961 ttaatattaa cagttccaac agctttttat tgaacaaacc atgtaaaacc agaaaatcag
     7021 tatactgatt ttctggtttt ttgtttttta gttatttatg taagattgct tcgataattc
     7081 tcaaaacgaa ataagtaggg aagttggaga ttttgattat cttcgtaact gacgaagagt
     7141 aaatgaatcc atttggtatg cactcttaag ttcaaaatat tggtatcgat gtttaaaaga
     7201 aatagaaatg tatcgaagaa cagatgttta aaaaagtgtg actttgtata aataaattag
     7261 aagaagcaaa cgaggatgtt aaaagaatac catatagtta ccaaaccaag aaagttctcg
     7321 tcaagttcgc tggtacgaat caaatcaagt gaaaaaaggg actgtgaaaa aaattgtgtc
     7381 atagttagtc actttttccg aacaaatagt gttcaatcag ctgtccttcg gtattagctc
     7441 aaaaaacggc aaaatatgag gaactatttt tccatttgtt tctctaatac tcaggacaaa
     7501 acactgattt tacaacctct gataaacggt gttcaaaagc cagtttctcg gtattaagcc
     7561 aaatttatgc aaaaatgtgg aaagccattt tcacaaaatt tttcttaata ctcgaaacta
     7621 agcgactttt tcacaacctc tgataaacgg tgttcaaaag ccagtttctc ggtattaagc
     7681 caaatttatg caaaa
//
LOCUS       DACCVZ010000113         7637 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.116, whole genome shotgun sequence.
ACCESSION   DACCVZ010000113 DACCVZ010000000
VERSION     DACCVZ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.116"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            138..1529
                     /locus_tag="IVW63_002599"
     CDS             138..1529
                     /locus_tag="IVW63_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP7860835.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(1602..2249)
                     /locus_tag="IVW63_002600"
     CDS             complement(1602..2249)
                     /locus_tag="IVW63_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP7860836.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(2257..2943)
                     /locus_tag="IVW63_002601"
     CDS             complement(2257..2943)
                     /locus_tag="IVW63_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860837.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(2949..4022)
                     /locus_tag="IVW63_002602"
     CDS             complement(2949..4022)
                     /locus_tag="IVW63_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAP7860838.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            4244..4918
                     /locus_tag="IVW63_002603"
     CDS             4244..4918
                     /locus_tag="IVW63_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7860839.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            4923..6263
                     /locus_tag="IVW63_002604"
     CDS             4923..6263
                     /locus_tag="IVW63_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7860840.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(6412..7398)
                     /locus_tag="IVW63_002605"
     CDS             complement(6412..7398)
                     /locus_tag="IVW63_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HAP7860841.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         2377 a         1397 c         1334 g         2529 t
ORIGIN      
        1 agggaatcac accaattttc ataccaattg gtttcattta tgaagttgat tccttcgatt
       61 aatgagcgtt tcattgaaag aaaagggttg agggagaaaa acatatgatc aggttgttgg
      121 aattaaacta tagaaagatg gaaaaaatca ttcgaattct gtccatttct gacaagtgga
      181 tgactaaaaa agaacttgcc aaacgaattg gtagttcaga atctacattt gtaaggtata
      241 tcgaagagat caaaatccgc tggggaacgg atgtaacgat tcaatcttca caaaaattgg
      301 ggtatcgtct tgaacatttg aatgtaccag cttatttaaa tgttctgatg gaaatgtcgc
      361 aaagttctac aaacagtcgt ttattaaatg agattattgt caatccgggt aaaacgattg
      421 agtattattg tgaaaaaatt tccatcagcc ggtcttcttt tacacgtaag ttgaaacaat
      481 gcaatcaaat tttagaaagc tatttattaa aagtgatcgt tgaccaaggt tttcagttaa
      541 ctagccttaa aagtgagctc cagttgcgta tctttgttac ctttttcttt ttaagttact
      601 acggaagacg cacgttgcca tttccaatcg aaaaaaagaa gatcaaagaa attatggtca
      661 agaataattg tcagatgaat ttgtttcagg aagaaagccc atatgagcaa tctttcttta
      721 ttatgtattt tgttgtgcat ctcatgagag aatcccaagg aactccattt gaatggaaag
      781 ctggagactc ttatgtacag ttgataaata tcgataaaaa agacttctta atcttgaaaa
      841 atctcttagg aaaattgaag tacagcagct atataaaagt agtgaactat tttgtcaata
      901 cgattttttc agaattttcg gagaaagaaa aaaatgaaat cagtgagcag atacgaaaaa
      961 atatgtccta ctgttcgttt tcatccgctg attgcaaaga aaaaaacgaa gaatatgttg
     1021 ttcaattatt aacgcaaatt tattttttct cccgtatttt cccatacgat acgactcatt
     1081 tgacgatccg tgcaacttac tttgcacagc agatgcaaca ccgccagata cgtctatatg
     1141 ctggatttcg tgcagaactt caattttatt ccactctact gaatcagaat ctgatttatt
     1201 atttatctag ctatatcttt tggatgctta tcggtaatcc tgaaattcac cattatactt
     1261 ctgataaaaa aatactgatt atcagcgact taagtcttcg acatagtcaa tatattgaag
     1321 aatatatcag tgatattctt gctgtgcata aaattcactc tgagacaact gctattactg
     1381 aagatcagct gtcgaaatac aatcttctcg agtatgatct gatcgttacg aatcaaccca
     1441 ttttgaatgc ccatgttcct catatattga ttgatgatag tgtgtcattc gcaaatgaag
     1501 aagaactcat ccgcttattc gagttatgaa taatcaaaaa acagctatgt ataaaccacc
     1561 ctgataaaaa tttcaggaca aatacacata gctgtttctt tttattgtat tccttcagca
     1621 atccaacgag atttatagcg aaagtctttt aacaactctt cttttgtcca attatttgca
     1681 atgagatccg tcaaagtgtt cattacgagg gtcatggaaa agtataggaa actaactgct
     1741 tcttccgacg attgaatgga gaaatgattg attcttaata attccagcca tttttcgttc
     1801 attggagaat cagccgatag ttctctacgt ttggttgtct gctgatcatt tcgctgggtt
     1861 aacaagtata acctttgcca atagatactt tcgtgatcta agtcgcagca ccactctaaa
     1921 tatttttcga tccccaaaaa gaaatgttgt ttgttttcgc taatgaattt taagatatct
     1981 tgatggacta tgtgagaact gcttttgatc gtatacaaat aagcatcttc caaatcttga
     2041 aaatatttat aaaaagcacc gcgcgacatc cccatcttgt caacgatttc tgagactttg
     2101 acttggctga tgtgctgtga gcaaaatatc tccagtaata ggtcatcgat tctctgtttc
     2161 tttgcgttcg ataaattgaa aaaagtttct tttggcatcc acatctctcc tttatctctg
     2221 attatacgtg gatagccctt cattgtcatg aaggattcat tccttctttt tctcttcttc
     2281 tgtcaagtac ccatcttcca ttcgataaac gcgatcactc cattgaatca tacggacatc
     2341 atgagtaacc ataatagtcg ctttttgttt ctcatgagct tctttaacta gtaatttgac
     2401 gacttcatat gcatgatctg tatccaaact agctgttggt tcgtctgcta agatcaagct
     2461 tggctcatta tataaagcgc gagcaattgc cactctctgt ctttctccac cagaaaggtc
     2521 tttaggataa ctatttttaa gtgactggat atctaaagat tgcagcaagg aatcgatttt
     2581 tgttgaatct tctttttttg aagtaacttg gtcaactagt tcaaattgtt cctttaccgt
     2641 taaaaaagga atcaaattag agctttggag aataaatcct atttctttaa agcgtaaatc
     2701 tgctcgtttt ttttctggaa gctcagttag tgagtgaccg ttgatcacta tttctccgga
     2761 agtcggtgtt tgcaatcctc ctgaaatggt aaggaaagta cttttacctg aaccagaagg
     2821 accaatgatg ctgacgaatt ctccttcctt tacataaaaa tcaattgctt tcaaagctga
     2881 gacctttgta tgaccagaac caaatgtttt ggtaactttt ttcatcgtta atattttttt
     2941 catttttatt aacctcctat tgctgtaatt gggtctactt tggttatcgt acgtatcgaa
     3001 aacaatccgc ctagcattgc gacaatgatc aaaatcccac tatatagcaa ccattgtgac
     3061 caaaaaacag caaaaggcat cgcgcttggt aaaatcagac tagtcaaata agcaaacaaa
     3121 agagcaagca gaacgcctac caccccaaca ataaaggact gtgctactaa agatttagcg
     3181 atgaagaaat ttttgatccc ttgtgctttc attactccaa aaatagcagt cttctgaagt
     3241 gtcatcacgt acatgaaaat accgaccacg gcagcaacca ctaagaacaa aaagtatatc
     3301 atcgcattta aggtcatatt ttgggcagaa tagccaggaa tactttcaat gaatgtccca
     3361 atagttaata actgtagacc cttcgatgct ttttctttcg aaattttagc tgaatccttt
     3421 attacgatcc cattgatcgg ctgttcttct tcagaagcaa acggctgttg tccatacttc
     3481 aaagcagtcc acgtatctag ggacgcatag atgacgggag aaactgtgta ataagtttca
     3541 ggaaagatac cgacaatcgt caaaggatcg tcgtaactgc caattttgat cgtatctcca
     3601 attttatagc ctgaatcagc cagattttga gagatgatga tttcattctt tgttttaaat
     3661 tcatgccctt tcgtgagttt tggtaataaa aatgcttctt tcgttgtgcc gaaaactgta
     3721 acattttctt tgttttttcc tttgattgct ccgctgtaca atccgattgg tgctttctct
     3781 cctccttcaa tgtatttcag atctcctctt gttaattgtg aagctgcaaa tacttgattt
     3841 gcatcctccg acaaaacaat ctcttgtgcg tcccaatcat cgattgcttt tttaaactct
     3901 tctgaaagtc cattcgctag tcctgacaac atgaatacga catacgcaat caagaacata
     3961 ataccgacga tcaagccata tcgtaattta gaatagcgaa tttctttgat agctagaaac
     4021 atttgttttt cctccctatg atagattgat agtgacaaaa tgtcacttgt tgaatagtgt
     4081 aactctaaag tgacaatttg tcacttgtgt tgtttttttc ttatcaataa attgtctaag
     4141 acatctttcg ataaaacctt aacatgagtc ataaaaaatt tatttaagcc ttatttatgc
     4201 tttccatgat aaactaaagt gaccaaatca atgaggtggg aaaatgatta aactattagt
     4261 agtagaagac gataaagtat tatccaataa tataaaagaa atactcgctg caatcggcga
     4321 gataacacaa gtttatgatg gtagtgaagg actgttcgag ttggaaagtg gagtttatga
     4381 tcttgcaatc ttggatttga tgatgccgga aatgaatgga tatgaagtgt tagcaaaaat
     4441 acggaaagaa aaaatacaga ctccagtatt gattttgact gcaaaagata gtttggaaga
     4501 taagattgaa ggatttgaac gaggtgcaga tgattatcta acaaaacctt tctatcgaga
     4561 agaactgatc atgcgcgtga aagcattatt gaaacgctcg ctaggtctct ttgatgaaaa
     4621 tgttctgaag tataaggata tcagttgtga tttaaaaagc aatgaagtct tgtataaaga
     4681 acaagttttg cccatacaag gaaaagagtt tgaattgctc gtttattttt tacaaaataa
     4741 gggaatcatt ttgacaaaag agcagatatt tgaccggatc tggggatttg attctgatac
     4801 gacgattaca gttattgaag tttatatgag caacttacga aaacatctgc gaagtactgg
     4861 attggataaa gaaatcaaaa ccttacgtaa tgtcggttat atactgcaaa gggtgtgatg
     4921 caatgaatgg agatattaca cgaaagcaac gtagtcgctt ttttgcgaca aatgtagcag
     4981 catttgcttt tatctttttt cttttgggat tcattacttt acagatatta aaccaatctg
     5041 catacagaga aacagatctg tcattagaga aaataaattt tgattctcga acagtacaat
     5101 tagagataca aagatatcag caaggcgatc cctttttaaa cccgactcaa acggaacaaa
     5161 acagaacaaa catggaacag ccattaatgg aaccatcaaa tgaccgtttt aacactcaag
     5221 tgatcttgtg gtctaaaaat ggtgagatat tgaataaagc agctattggt gggcgtttca
     5281 accaaatcaa agaattaaaa atggatacga aaaatctgaa taccatccaa aatattgaat
     5341 taaatgaaga cagtggctca tctgccctct ctttccgttc gattacgaaa aaagcggaga
     5401 cgaatcaaga tggcgttgcc tacatccaaa ttttagaaaa tacaaatcaa atcaagaatt
     5461 cattagcgac ttttcgcacg attatgattt tgtgtatgat tgttttttgg attctctcta
     5521 ttggtatcag ttattacttg tctagtctaa gcatgcgccc tattattctt tcttggagaa
     5581 gacaaaaaga atttgttgag aatgcttctc atgaattgcg cacaccgtta acgattattc
     5641 aaaatagttt ggaacatctt tttaccaagc ctaatcatac tattattgaa gaatccgaaa
     5701 gcatcgctca agcattgtca gagacgaggc gcctcactgg attgacttcg gatttgctga
     5761 caatcgctcg gaatgattct gatcagcagc tgctttcaaa gcaaatgatc aatacacaag
     5821 aatatatcga acaacttgtt aaaccatttc aagagatggc catcatagat ggaaaagagt
     5881 ttattctcca taacgatgca acattagaag taccaattga tgaaaaaaaa atccatcaag
     5941 ttttggttat tttgctggat aatgcattaa aatatacgaa tccagaagat aagatcattt
     6001 tggattcatc tgttaaccat aaagaatggc tgattcacgt aaagaatact ggcccttcta
     6061 tcagtgaaga agatcaagca aggatttttg atcgatttta tcgggaagat caatctcggg
     6121 cgaaagagac tggcggatac gggcttggct tggcaattgc aaaacaggta atcgaacagc
     6181 atcatggaca gatttctgta tccaattatc ttccacaagg agtcgatttt aaagtccaat
     6241 tgccgttgaa gcctaaaaaa taatgcttat ccctaaaaaa gggctgtgac aaaaatcttg
     6301 tcacagccct tttttgttgc gaataaacgg tgttccagaa gtagcttctt cggaaataag
     6361 ccgaaatttc tttaagctga ccacttctgt cacaacctct ttagcttacg cttacgattt
     6421 tttattgcgg tcttcaatgt gtacatcacc gcttgtgtca atatccaatt cttctcggct
     6481 aacatcttct gtcacttttt caacatcttc atgttcttct ttatgaatcc caacttcttc
     6541 acgaataact gtatgtttgc ttacatctac ttgctcttct ttgattggga tagtaatcgt
     6601 gtcatcttcc aatttttcgt ctgttccctg tgaagattga tctgttactg gtttgcgttc
     6661 gatgacgatt tcttcacgtt tgaccggtac ttctaccgtt tcagtatcgt tgaccacatg
     6721 tttgtggatg tcgacttctc cagttgtcac atcatgtgta tttacatcta atttttcttc
     6781 ttttagttga attgtatcat catctagatt tggtttgcga tcgatgtctt cagtcttgct
     6841 tgtacccatt gtatcagtct cgccaggtac gtccatcgga tcagttcctg gtgtcatatt
     6901 caatggatcc gttgtatttt gaaagcctgt cgtgccacct acgtccattg gatctgttcc
     6961 agtgccagtt tctaatccag tccccattgt gcttgctggg ctaacagtat cttgtgtatc
     7021 cattgtatct tctgttgttt ctggctgacg atagcctttt actgtgatga caaattttcc
     7081 atcagaaata tctcctctat attgatataa aggatcattt tctggtgtag ccgtctcaga
     7141 atcataggta tcaaaagaaa aagtatcttt tattttttcc cataaagaac ggtcttcttc
     7201 accatccatc cgattttcat ctgtttcaac atctatacca gacaatccgt caaatcctag
     7261 tctagatgct gcttcatcag tagtataaat aacgatatca tctcgttcat acccttcgtt
     7321 acgcaaccgt tcaattactg ataatgcttc ttccctcgta ctatagcttc cgatgaccgt
     7381 taaatttttc tcttccatgt aaattcctcc tagcaaatag atttatgatt ggtatattgt
     7441 tacttataaa tttattctat aggagacgat tgttttctac aaatatttag attggaattt
     7501 gattaaaaca atttaattga aatttgaaaa catttatgtt aatgaaagtc atattctaat
     7561 aaaatgtcat ttgtttctat atgaattttt atgaaaaatt tcatataatt tccactcgtt
     7621 gtgatggttt aatttat
//
LOCUS       DACCVZ010000114         7627 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.117, whole genome shotgun sequence.
ACCESSION   DACCVZ010000114 DACCVZ010000000
VERSION     DACCVZ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7627
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.117"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(16..708)
                     /locus_tag="IVW63_002606"
     CDS             complement(16..708)
                     /locus_tag="IVW63_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP7860842.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            793..969
                     /locus_tag="IVW63_002607"
                     /pseudo
     CDS             793..969
                     /locus_tag="IVW63_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1145..1714)
                     /locus_tag="IVW63_002608"
     CDS             complement(1145..1714)
                     /locus_tag="IVW63_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP7860843.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1788..2111)
                     /locus_tag="IVW63_002609"
     CDS             complement(1788..2111)
                     /locus_tag="IVW63_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860844.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2265..3077)
                     /locus_tag="IVW63_002610"
     CDS             complement(2265..3077)
                     /locus_tag="IVW63_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860845.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3431..4279
                     /locus_tag="IVW63_002611"
     CDS             3431..4279
                     /locus_tag="IVW63_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAP7860846.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4424..5365
                     /locus_tag="IVW63_002612"
     CDS             4424..5365
                     /locus_tag="IVW63_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HAP7860847.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5355..7526
                     /locus_tag="IVW63_002613"
                     /pseudo
     CDS             5355..7526
                     /locus_tag="IVW63_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2273 a         1512 c         1372 g         2470 t
ORIGIN      
        1 agaggggggg attttttatc gttgtggaat atttaaatac caacgcttgt catgaaaatc
       61 ttgtgctcca cccttagtat ttccttctgg atcgtttgtc gcacgcatca tgacgtatac
      121 tttcttatta gggaaatcac gcatattgaa agatacatga tagccaacat ttcctaaagt
      181 attataagct tgatttacgt ctggtctata aatcccatca gctcttactc tagctagttc
      241 ttttccagta ttgtagtcca taatgaaaat atactcgtat ttataattag caatgtgcca
      301 tccagctaca tgcaagtttg cgttttcgat ttctccgaac tgatcaatgt gggcgtaatt
      361 tgttccatct gtcagcgtag aatttgcagc acctgctcga gttggatcaa ttactggttt
      421 atcctccgaa gtagttggat tatcatccgt aaaaccatga gccaaatcat aggctagttt
      481 ttctttactt acacctattt cagaaagata accgtaagga tctgtatgat cgccccaaat
      541 attttgtgtt acccataaat gcgatttgat tcctggttgg ttataaggag tgtctaatgt
      601 taatggaata ccatatttca ttgctgaatc tcttgccaat tcaacgtata ctttatagtt
      661 cttttcaaaa gtttctttat catgtgtgtg ttgtaactcg atttgcacag gacttttggc
      721 tcacgaggtt gtcctactct acatcttgct gatagatatg ctgaaaggaa aacaccaaca
      781 ttatgttttg ctttttcagc tagaacgaga caagcaggaa tacctttaga agatatcaaa
      841 ggttttttag gtcataaaga tgtttccact acacaagtct atgcccatat ttctcccgaa
      901 gtgaaaaaaa gatcaatgaa tcaactagaa aactatatag aagagcaaat aaaaaagcac
      961 tcaaattgag tgctttttta agctcactat cactaaaact atcactaatt ttatttataa
     1021 gcgaacatgt ttctatcact gattttttaa atctagcgaa aaacccttat cttaaaggcg
     1081 ttcgttcaat tctttggcaa ggtcttcaaa gcctggcttg cctagaagtg cgaacatggt
     1141 tttcttatag ctcatgtaga aaaattttct tgatgatgat tttatccatc aattgagatt
     1201 gactgttttg ctctcctatg atttcagcta tgattgtccg attttgcggt tttcttctta
     1261 actggtagtt gattttccca gtttccatca actcgctaag catatccacg actccgccaa
     1321 atccggtctt tttcgtaata aaacctagtg ctaccattcg ttcatctaga ttttttgctg
     1381 taatcgtcac accagtaatg agcgagtgct gtaatgtttg ggccagctct tccatccctt
     1441 cagcattgga tacgacggaa gctgttttgt taataggttc ttcgtttatt tcttttggtt
     1501 ctttcctctc cactttcact gtttgacgaa ggacatctag ttcttgcaag agcgtttcgt
     1561 attgttcttg ggtcagcatc acgccagcta ctttttcacg attaaatata tatacgccag
     1621 ttcccgcgtc tcgcgcttga gcaaatacat ccatcggcga tcgtttcact tctgtgatcg
     1681 aagatgtggg aacttctaat ttctttaatt ccaatggatt tcctccttta ctaatcgctt
     1741 tttattatag cacagactga cttgttttga tcttttttcc aaaggtttta tcggtttttg
     1801 cctaaccagt aattgatatc ggtaagaagt ctttcgatac caaatgaagg atggtacaga
     1861 tacgtttttt gatcttcgtt atggtctagt ggaaaaaaat gatcgatgat cactagatct
     1921 gcataccgag gcggcttatt tcgagtacat acatgtatag agatccgttt tcgatgtctt
     1981 agcgttttgt tcagtacccc agcaagtctt cttgcttctt ggtgttcata gcgaaaaaaa
     2041 aagacgattt tcacttcagg agggtggaca tctaaatacc ctcgttcctg gagtgttttc
     2101 agtaaaagca tcccccactc tactgcgggg tgtgcaagtg cttgttggat cgctagccga
     2161 aattgatata gtttatcttt ggaattggga aatttttcta atgtttcctg ataataacga
     2221 acttcttcta tcagccggtc atggatacca attacgtaac gaagtcattc ttggtaaagt
     2281 acttttgtca gctttgattt gctttcgctc tcaaattcgc tattcagcca aaacagcgaa
     2341 tcaagctttt cagtcacaat cgtcaatttc cgatagtctt gtgtctcttc tatccgtttc
     2401 caccgctttt cagtaatctg gttacagctc aagcgcaaaa ttgctagata atttttttct
     2461 tttattggca aaatctgctc ctctctaaat agcaattcag gaaacaattc aaagaatagt
     2521 gttcgactgt ctcctaaaat ctcgatttct gccggatcct ttctttgctt caataattgg
     2581 atgaacatct cagaaaagga ctgctctcca tcatctgcaa aaaaatgcgg aaaatctttc
     2641 aaaaagcaaa acagcagata tcttactttt ctttctgaac caaagatctg tgctttttta
     2701 taagaaaaag aaaggtggta ctcgccaaac cactttctca atcgctcttg cgtagaacga
     2761 tcgtacttct gctcgtaagg ttcattcaat agcagatttt tcagtaaaca aaacgggggt
     2821 gattggatca gaaaaacaaa caagagataa ggttcgctat atccttgatc ataaactaac
     2881 tgaacggttt tcttatgaag aatcagctga atgggacagt cgctttccgc caaacgtttc
     2941 agatgccgat ccactgtttt aacatcgatt ttcagttctt cagctaaatc agcttttcgc
     3001 cagatcaaat ctttcattag attgattagt gaaaataaat tctgtgcatt ttttgataat
     3061 agtttttgcc atctcatcga tcatttctca cctgatttct aaacatattg tttgatcaaa
     3121 atgggttcac tcctaaaaag ataaaaaact ccctttctat ttatttaaat acgcaaatct
     3181 tcctcattat tttttatttt actcaattta atcgtattct catttcaaaa cgaatgtact
     3241 ttaaaaaaac ataataagat cactttgctt gtaggatgta ttcccttcca ttacaatgaa
     3301 ataaatagcg attttatgag aaggtgatgt gaaaatggaa gaaaaaatag aagaatccaa
     3361 acaaaaaatc gatcagttga tataagaatt agaaaaagcg gtcatcggca aacgttcaac
     3421 tatccaattg atgatcgtgg ccctattagc aggtggtcat gtcttattcg aagatattcc
     3481 cggtgtaggt aaaacgttac tggtcaaagc actagcaaaa gctgtacagg gaaccttcag
     3541 cagagtccaa tgtactcctg atctgctgcc tagtgatatt cttggttttt ccgtatacaa
     3601 ttcacaatca aaagagtttg aatttcgtcc gggaccgatc tttaccacga tcttgttagc
     3661 agatgagatc aatcgtacga ctcctcgtac tcagtcagca cttttagaag caatggccga
     3721 gaatcatgca acgatcgaca acaatacata ccctctagac aatcattttt ttgtcttagc
     3781 tacgcaaaat ccaatcgagt acgaaggaac atatcctttg ccggaagcac agctcgatcg
     3841 ttttttattc cgactacaaa tcggttatcc ttcttttgat gacgaacttt tgctactttt
     3901 ggataaattc gaaaaagtgt tggataactt aaatgaagta ttgaacagtt atgaaataga
     3961 agaaataaaa acaaatgtgg cgaatgtctt tgtcagtccc gaagtggcat cttatgcctt
     4021 gcagttagtg tcagcaacaa gaagtcatgc tgccatccag cttggcatca gtccacgagg
     4081 aagcctttcc tttattcagg cagcaaaagc ttatgcttta atccatggga gaaattacgt
     4141 cacgcccaaa gatttgcagg atttagttcc ttacgtgttt tcccatcgcc tgatttttta
     4201 cgatcgttca ttgaaggaag acgaaaagaa acaaatcatt catactcttg ttgcacaaat
     4261 tcctattcct gtgaggtaga ttgaggtaga caatggaaaa aatcaaagat tatttcatta
     4321 attttgtgtt atttctggta tatttcatca ttgtgctttt tgctcttgta ttcaacaatt
     4381 ctttaggctg gttcttgttg gcctttttta ctctttatgt atcatggagc ttgatttcat
     4441 taagcagctt tctaaagaaa ctttcggtta cttgtacatt gcagccactc gtttatcgca
     4501 aaaaaagtat gcaggttatt ttttccatag caaaaaagag aactttttct ttacctctcc
     4561 ctcgtttaca aatcggcttc ccagcaatct ttgcagaaaa aaacaagaga ttttgattct
     4621 tacaaataaa ccgcaagaag tccaattgct ttggcagcca aaagaaagag gatgccatga
     4681 aacattaact gtcattttta cagcctatga tagtctagga cttttcagaa aaagtgcaaa
     4741 aagagagatc tcttttcctg tgactgttct gcctgctttt tgtaagattc aagcagaaaa
     4801 attacagaga gttctggaaa aaaaacagca gctgaacgcg taccaaagag gtcttgattt
     4861 tcgggaacat cgcgcttatc gtccaggtga ttctttcaac cgaatcgatt ggaaattgtc
     4921 tgctcatact caagagtggt tataccgtga atacgattat caagaagaag aatgttctcc
     4981 tcttttttgc ttttggggtt cgcccagtcc aaaatttgaa cctctgctag acttgtattt
     5041 ttctttatgg catttgagaa aagaaaagca gccggaactt ctgatattag gcaaccgcgc
     5101 ctttcatggc aaagaccccg gtcataccta ttttgcttct ttggaagctg gcgatgagaa
     5161 aacttttttc gcacacttga aaaaatatgc aaaaaaacaa atcgtcctct ttgttcctga
     5221 gaattctcct gaagtctcag aagctattga aacattgtca aaagatcgaa cggtttatct
     5281 tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa gacaagatat gttcattgcc
     5341 aggaggtgaa tggattgacg attaaacggg aaaaatggct gcgtggcgtt tactcctttg
     5401 tgatactaag tgtaggtgct ccgatatttg tagtagctaa tcaattgcaa aacagctacc
     5461 ttcttatcct aactattggt gtcctatgcc ttattgtctg ctgtattcct aaaaaatggg
     5521 tacgtttgct gctttctttg ccagtaatga taggttgttt gtttttatat tttccttcga
     5581 agacattttc catattatgg atcttacagt ttttttcgtc agttacagag gaattcttcc
     5641 atctatccca aggtaaactt tattatttgc cagaaaagac agcttttttt ctcataatgt
     5701 tgctgatcta tttatttatt acattgaccg tggattacga ctattggtac gcaccctttc
     5761 tttctttgat ggcttacttc atgatgctta ccgtttttcg gaaaaaagat ttactgtacg
     5821 aaatgattgc ggtagtaact gttttgttcg tgtatctggc agcaaggcaa tttttctcca
     5881 tccggttgtt gtcgagaaac actcgattcc agtcattgac tacagttctg cttatttgtt
     5941 tcttaacttt tagcgctatc ttgcctttat atcttccgaa agtacaccaa tctctcgagg
     6001 aaacgagtga accgatccga gaatatctta atgatgaagg gctttatgac acactccatg
     6061 agtatcaatt aaccggaagt gcaagaacag gcttcagtga gaatgatgaa cagcttggtg
     6121 gacctttata tgataatggc gaagttgttt ttacagcgaa ccaaaaagga aatggctatt
     6181 ggaagatcga aaataaaaat cattacaccg gttctggatg aatagaagat caggacgcac
     6241 ccatccaacc aatccaagaa ttccctgttg acatcacgag ctaccaaacc gttatagaag
     6301 acaaagaaaa cattacattg accctaaaaa aacaagcttt cttaccttat ccttatggaa
     6361 atactacctt gactgatttt tcattagcta gtggacaaac gctttactat ttgcctgaaa
     6421 gccagcgatt cattcctgtc ccgaatgaat cgacacgttc tgcaacttta caaacagaaa
     6481 ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt aaaagctgat gatttagaaa
     6541 atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa acgtattgag gacttggcgg
     6601 tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt cgaagctgtc taacagtatt
     6661 taaaaacaag cggaaatttc cgctattcca aaacggatac cgggcatact ccaaaagaac
     6721 acgattatgt ggattatttc ctctttgatt caaaagtcgg ctattgtgac aacttttcaa
     6781 cttctatggt cgtccttctt cgaacacttg gtatcccagc tcgctggaca aaaggtttta
     6841 caaatgggct cagaacaggc acagataatc aagggaatga ggaatacagc attctcaata
     6901 gtcatgctca ttcttggcca gaggtatact ttcctggatt tggctggctt ccatttgaac
     6961 caaccccttc atttgccaat ccaatgggtt cacaaccagt tgctgaaaca accgaaaccg
     7021 tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat ggcagaaact atttccagtg
     7081 agagatctga ggtcattcca tcagaagaaa caacactcac accagcttat aaaatcgtct
     7141 tattcagcct tggagtgtgt ttatccgtct tgttgttctt tctattgtta ttcagaaaat
     7201 ctctgcgctg gacaagttat cttatctatc ttcatttttt tgcttctact aatacgattg
     7261 catatcaaaa acttcttaac cctttggaaa cattggtacc gcgcaaaccc gcagaatctt
     7321 tgcaggaata tagcctgcga atagaacaag aattcaagct agatctgcgt ttcattcgat
     7381 taactactca atatgaagca gaaatatatg gacgacaagc agatccggta aaattcgata
     7441 aaaaaaccta tttagaaata acgcatataa taagaaaaac ggtatacaaa aaaattctga
     7501 caaaagggag ccgcttcaaa aaataagata aaatttctgg agaatctact tctcgaatgc
     7561 cgagaaccag ctgattgagt atcgattact cgaaaaaaag gttgtgacac gttttttgtc
     7621 acaacct
//
LOCUS       DACCVZ010000115         7099 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.118, whole genome shotgun sequence.
ACCESSION   DACCVZ010000115 DACCVZ010000000
VERSION     DACCVZ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.118"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(125..733)
                     /locus_tag="IVW63_002614"
     CDS             complement(125..733)
                     /locus_tag="IVW63_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
                     /protein_id="HAP7860848.1"
                     /translation="MREVEQLLNAYSSVNDPKTVQTVQALAAEKIRDILDHELPEIDT
                     FLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVKKLKQPAWNEIDLQ
                     EHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQKTSNVSLFLSTTK
                     AGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(743..1702)
                     /locus_tag="IVW63_002615"
     CDS             complement(743..1702)
                     /locus_tag="IVW63_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP7860849.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            complement(2246..2749)
                     /locus_tag="IVW63_002616"
     CDS             complement(2246..2749)
                     /locus_tag="IVW63_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP7860850.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(2872..3636)
                     /locus_tag="IVW63_002617"
     CDS             complement(2872..3636)
                     /locus_tag="IVW63_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAP7860851.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            3744..4019
                     /locus_tag="IVW63_002618"
     CDS             3744..4019
                     /locus_tag="IVW63_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAP7860852.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            complement(4220..4567)
                     /locus_tag="IVW63_002619"
     CDS             complement(4220..4567)
                     /locus_tag="IVW63_002619"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860853.1"
                     /translation="MIPSVSFLFKKLKTFFILPEIEESNELTASDRSAFLLPVFNTWG
                     KAPQKQPYRRCSKVSFLVLRQIYAKMWKAIFTKFSLILKTKRLFHNQSLMLDADQLFH
                     NLIDGVLSAASRY"
     gene            4735..5664
                     /gene="yidC"
                     /locus_tag="IVW63_002620"
     CDS             4735..5664
                     /gene="yidC"
                     /locus_tag="IVW63_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAP7860854.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQPKNSTNNKGRNAGKQQKRK"
     gene            5767..7099
                     /locus_tag="IVW63_002621"
                     /pseudo
     CDS             5767..7099
                     /locus_tag="IVW63_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
BASE COUNT         2158 a         1354 c         1300 g         2287 t
ORIGIN      
        1 aaggggctgt ccccagactt tagtaggcgt cattagctat ctttcgttag catttaaagg
       61 cgaacaccat cacctattca cttccattaa aagatagcat atttttctgt aaaaaacaat
      121 aaaattatcg ttctttcttt acacgttcag caaattcata gaaaggagcc aatttcgtta
      181 actgttgatt acattggtca ctatcatgac aaatataatt cccctttttc gtatacgtgc
      241 catcagaacc tgctttcgtt gtagaaagaa aaagcgaaac attcgatgtt ttctgacaga
      301 ttgcacagat tcccttattt atcgttggtg ataaagtacc gctaatccct tttaattttt
      361 catcttcgta atagaccatg aattttttct gcgtacctgg atcattccag ccgatgtacg
      421 tatgttcttg caagtcgatt tcattccaag ctggttgttt gagttttttc acttttcgga
      481 ataatttctc gatttgtggt ttgctaggct gcataaacgg ctgaacgatt tgcttcagct
      541 cctccaatgc tctttctgct tgcgcttttg tcagttttac gtctaaaact gtcgttaaaa
      601 atgtatcgat ttctggcagt tcgtgatcta atatgtctcg aatcttttca gctgctagtg
      661 cctgaactgt ttgtaccgtt tttggatcat tgacagatga gtacgcattt aataactgtt
      721 ctacttctct tattttcgtt tgtcaaatta agttagacaa atcatctttt gtgacgtaac
      781 tcaaaaatac ttccattggt gtccgatagt gtaatgattt tctaggaata tgatttcgtt
      841 tcgatgccac cgattggata aaggtttcag atacaccatt aaaatccata gctttataca
      901 aaccatcttt acgtaataag ccatttgaat gttcattcaa tcctcgttga gaaggtgttc
      961 ctggatccgc aaaataaatt gaaatatcgt tggtattact aatctttttc caatttgaga
     1021 attcttttcc acaatcaaat gtgatggatt taaataagtt ttttgggaca caacgaaacc
     1081 attgattcag cctattttca atgtctttag cctgtctgcc ttcgggtttc aaggtaatga
     1141 tgactttaga tagccgttca actaatgtga tgaccgcgct tttatgtttt ccacccacga
     1201 tagtgtcacc ttccaggtga ccaaattcat gatcaaactg ggtatagtct gtctttctgt
     1261 ctcggattga ccggcgaaac ccttgttttc ctcttttttc tttatgaccg tttggttttc
     1321 tttttccctt cattggtaaa tcgtgagtgt caaaggtttt atctttaaac attcgataca
     1381 gtgtgcgtac cgaacaagca ataggaaact ctgctcgacc aataaggaca tcaggagccc
     1441 acccttgaac aacctttttt tgaatgtatt cctgttgctc atcaggtaaa acaatcggat
     1501 gtcttccgca gttacgtttg tttttcttat attgtttata gtagctcatt gcgcttccac
     1561 cagatttaag aaaacgatag accttataaa tagtttgtcg agaacgttgt aacagattgg
     1621 ctacttttga aacaggttgt gattgattga aataagcttc tatcattacg agttcagttg
     1681 gtgtaagatg gttataggtc atttgtactc actccttata attctttcgt cggaactatt
     1741 ttgagtgtag cacaaatgac tttttttagt tgtctagctt aattttacaa tcggcgtatt
     1801 ataaaaaaat attggtatgg ttttattgtt tgttccatga ttttaaagtc ctttcttcta
     1861 accaaagtgc atactttgta gaaaaaagtg atcttctgca aagtatgtgt tacctgaaga
     1921 tcctggactc ttttaaataa gatacgtttt gcatcttatc atcaccccct ttaatgctta
     1981 ttattctatg tacatgattc attcgataaa taaaagtaaa ccgtatcttg aacagatagt
     2041 caactgcaaa cagaaaaaag gactgtgaca aaagtcgtgt caaagtccct tgtttcgaat
     2101 gaatggtgtt caaaagcttg catctgcagt aataagccga aacttcacaa aaatttgaga
     2161 agtaattttc gtaaattcct tcttatttct tgaagctgac cacttctgtc acaacctcaa
     2221 tatggtctat tattggtttt acctgttaaa tcgaggattc tttcccaaag taacgttgcc
     2281 atctcttacg catacttgca gacatgggct gagccgcttc tttgactgcg cagtatttgt
     2341 ccacgaatgt cacaatatat ccttctttat acttaggcgg tgcgatcgtt gcaccccaca
     2401 tgtgcttcaa aatgatatct cgctcaagat ccgacaaatc ggtgattttt tctgcattct
     2461 ttacagcaat tcttggatgg atatacgcat gtgtcccctc gtcaaatttc gtcgtacgcc
     2521 aatcatagta gaacagatca tgcaaaagtc cagcacgcgc tgttgcttta gcattgccac
     2581 cccatttttt tgcgagcaga taactatagt aagaaacact gatggaatgc tccaaacgag
     2641 tggaatgaac atgctgtgtg taattcgcta attttttcac tgcttctgtt tctaaaagat
     2701 cttgtacata agacatatat tcttcgtctt cacgccattt ttctgtcata attatcgatc
     2761 tgccaccttt ttgaatttca ttttcttctg aaattgatct aagtatacca ccagtgttcg
     2821 gattattcta gtcgctctag ataaaatagc taaagcttaa tagttcctta atcataaaga
     2881 aaaatgataa agaacgatcc ctgctgcgac tccgacattc aatgattccg catttccttt
     2941 cattgggata tatacgttct gatcagtcaa agacaagatt tcctgactga ctccctgacc
     3001 ttcgtttccc atgattatag cgaaatcctc tgttttttct actttgtcta atgcatgtgc
     3061 ttcttcattt aattctgtac cgtacaccgt aaaccctttg cctttcatta cagggattac
     3121 atctgccaaa tctttttgta acacaggcaa atgataattg cttccctgca tgcttcgcag
     3181 cacctttgta ctataaatat ctgccgttcc tttacctaat aaaacaccag ccataccaaa
     3241 cgcatctgcc gtacggatca tcgttcccac atttccagga tcctgtacat tatctagtaa
     3301 aagccagcct cctgaaaaat ctggcgtatc ttcagatgtt aacgtcatca ctgctaagat
     3361 cccttgcggt gtaggtagat ctgacatagc ggtcatgacc tcatctgaaa ctagaaaagt
     3421 agaaatctct ttgtttacag ccagccagtc tccccattct ttcatacctc tctgtgtcac
     3481 aaaaagttct tttatttctg catcagacga cgcagcttct tcgatcagat ggaacccttc
     3541 caaaagatat tctgcctttt cttctctgta tttcttttta tgtagttttt ttaattcttt
     3601 gattcttgga ttttttgctg attggatctc tttcacattc cttcacctca cctgattata
     3661 tcatggaata ggtgcttgag cttgtttcat cctaaaaaaa tcggtatcat tgatttataa
     3721 aacaggaaag aaaggtgacg aacatgcgca aagttaaaat gaatgtccaa ggacgtgtcc
     3781 agggcgtggg atttcgctat atgaccaaga tggttgctga tcagttaggc gtgaccggaa
     3841 cggtaaaaaa cgaagacgac ggctcagtca caatcgaagc aatcggaaat gacgacatca
     3901 tccaaaaatt tatcgaagaa gtcaagaagt ctccgagccc aagtggacga gtgcagtatg
     3961 tggatgtcca agaagatccg atgattgagg aacgaaagaa atttgatgtg gtgggataag
     4021 gttgtgaaaa ggtcgcttag ttttgagtat taaggaaaat tttgtgaaaa tggctttcca
     4081 catttttgca taaatttgac ttaataccga gaaactgact tttgaacacc gtcgataagg
     4141 ttgtttttga agcgctttgc ctcgagtatt aaggagaaac attttcaaaa tagcttctca
     4201 tattttgaaa tgtaatgact taataccgag aggcagctga taaaacaccg tcaataaggt
     4261 tgtgaaaaag ctggtctgca tcaagcatta aggactggtt gtgaaaaagt cgcttagttt
     4321 tgagtattaa ggaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgtctta
     4381 ataccaagaa actgactttt gaacaccgtc gataaggttg tttttgaggc gctttgcccc
     4441 aagtattaaa gacaggtagt aaaaaagctg atctatcact tgcagtgagt tcatttgact
     4501 cctctatttc gggcagaata aaaaaagttt ttagtttttt aaataagaaa gaaacacttg
     4561 gaatcactct tttctttcca agtatttctt tcttgatttt ttgtcttttt tcaaaatttt
     4621 tcgctacgaa aaagaaagaa tatttatatg aaatttctat gaagttgatt gaattccatg
     4681 cgctttttta gtatagttaa gtttgtgtaa aaattataga agaggaagta ttctatgaat
     4741 aaatggaaaa actggttatt gggatccgga cttgtcagta tcctgctctt tttatctggc
     4801 tgtgtgcgga tggattcaaa cggaaaccct gacacttcag gaatcgttta tcgagtactc
     4861 gtccatccta tgggccaagc gattacatat ctagttgaga atttcaattg gtcttacggc
     4921 tgggcagtta ttgcaatgac tgtgatcgtc cgtatcatca tcttgccact aggtatcagt
     4981 caatcaaaaa aaacaatgat ccaatctgaa aaaatgcaag cgttaaaacc acaagttgaa
     5041 gcagcacaac aaaaactaaa agctgcaaca acacgtgaag aacaaatggc agcacaagca
     5101 gaaatgcaac aagtatatcg cgaaaacgga ttgagtatga ccggcggaat cggctgtctg
     5161 cctctattga tccaaatgcc gatcttctct gccttgtatt ttacggctcg ctacacagaa
     5221 ggtatccgtg aatcatcttt ttacggcatc gatctaggct caccaagtat ggtgcttgtt
     5281 gccattgcag gggtcgctta tctgcttcaa ggatatattt caacaatcgg tattcctgaa
     5341 gaacagaaaa agacgatgcg tacgatgctg atcgtctctc ctgctatgat cgttttcatg
     5401 tcgatcagtg cgccagccgg tgttacactt tactgggtag tgggtggtgt gttcagttgt
     5461 ctgcaaacat tcatcacaaa cgttatgatg aaaccacgtt tgaaagcaca agtggcagaa
     5521 gagttgaaac aaaatccgcc aaaacaagtc gtcactccaa gaaaagacgt gacagaatcg
     5581 gcaaagccag ctgacaataa acaaccaaaa aacagtacaa acaacaaagg ccgcaacgca
     5641 ggaaagcagc aaaagcggaa ataaaaatat atgacaaaaa actgtagaca aataaaaaaa
     5701 tttctttgtt ctacagtttt tttgttacaa tcaaagaaaa cgtcgctttt cgaggaggaa
     5761 tgtataatga tgtccaaata atcaatggat agtcgaatgg aagaagccaa aatttcgcta
     5821 gatgcacttg ttcctaaaaa tcatttggtc cataaaattg acaaaatatt gttatttgat
     5881 tttatttatc caattgttga atcaacttac tcgaccattg gtcgtcctag cgttgatcct
     5941 gtcatcttag taaaattagt attcattcaa tatttattta ggattcgttc gatgcgtcag
     6001 tccattaaag aagctgaaac aaacctagct tatcgttggt ttcttgggct tagtttaatc
     6061 gataaaattc ctcatttttc aacgtttggt aaaaactatg tacggcattt cagagaaacc
     6121 gattgtttga acagatattt atcattatcc ttgaacaagc agttgaagct agatttattc
     6181 atgaagaaat tttgtatatg gattcaacct atattaaagc gaatgcgaaa aaacatattt
     6241 ttacaagaga aatggtacat aaataagcca ttttatacca aaaacaattg aaagaaaaaa
     6301 ttaatgaagc aagaattgca gaaggcaaac gtccttttgg ttcaatcatt catcaggagg
     6361 tggtagaagg gaaaattagt gtcgcagatc cagaaagtgg ttattatgta aaaacagaac
     6421 aagaaaaaca gtttgcttat tctgctcata ccgtttgtga tgaaaatggt tttgtattag
     6481 atgtcatgat tacgcctgga aatctacatg acagccgaat gctcgtgcca caaatcgaac
     6541 gtgttaaatc atgttgtggt gtagctgctg atgctgcgta caaaacacct tggaacgcca
     6601 agtatttaat cgatcgaaaa ctacgaccca tttttcctta tactcgaccc aaaagaagca
     6661 aagaacgttt taaaaagaaa gatttttatt atgatcccta ttataactgg tacctatgcc
     6721 caaatgatca aacacttcag tttcgcacaa ctactcgaga tggttataaa aaatatgtat
     6781 ctaaatcttt tatttgtgaa agttgtctat tattgaaaaa ttatacagaa agccagaaac
     6841 accagaaaga aatacatcga catatttagg aagactactt agatgaagca gaacatttac
     6901 gccatacggt gtacaatcgc gaaaaatata aaaaaaagaa aagaaacgat tgaacgcgtt
     6961 tttacagacg caaaggaaaa gcatggaatg cgctacacca aatatcgagg cttggaaaaa
     7021 accaggtgca tacgatgctt gtttttgccg caatgaatct gcaaaaatta gccatttggc
     7081 agtgggggca tatgtcttt
//
LOCUS       DACCVZ010000116         6988 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.119, whole genome shotgun sequence.
ACCESSION   DACCVZ010000116 DACCVZ010000000
VERSION     DACCVZ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.119"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..456
                     /locus_tag="IVW63_002622"
     CDS             <1..456
                     /locus_tag="IVW63_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP7860855.1"
                     /translation="TIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQ
                     SVPKNLFKSITFDCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRKDGL
                     PKEMEFNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
     gene            complement(524..1297)
                     /locus_tag="IVW63_002623"
                     /pseudo
     CDS             complement(524..1297)
                     /locus_tag="IVW63_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            1318..2520
                     /locus_tag="IVW63_002624"
     CDS             1318..2520
                     /locus_tag="IVW63_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HAP7860856.1"
                     /translation="MCTKLLQNTAHKNPYKTVDEATQLDLVIVVNQLLTGYDSKWVNT
                     LYLDKSLEYQNIIQAFSRTNRLNGPEKPFGTIRYYRKAHTMEQNIEEAIELYSGKQAK
                     GLFVEKLYNNLEKLNDIFEEIKSVFNISGIENFSHLPEVPGEIKQFVNLYNQLIHCYE
                     SAMIQGFTWAKSTYEIQDYEPITVVITEYEFNILAQRYSEIEREPRDGNDSIAYDIDY
                     QLPEGSRSRINYEYLNTNFKKYMNIKEERDSNLIQSLLNDLHRTFAQLPVELQPYAEM
                     ILNDVNNGELVIKEGWEFTDYLNEYQLSEEDDFIQDLVDSTNINEALLREMLDLRLTE
                     VNINEYSRFDKLKSSVNVGHFSGYIEKNLGKMVIPIKVNMLIDRLLRAFLLEDVFDVT
                     EYIKNYFN"
     gene            3253..4221
                     /locus_tag="IVW63_002625"
     CDS             3253..4221
                     /locus_tag="IVW63_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP7860857.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADARNHDLDVRRYMGKVEY"
     gene            4232..5047
                     /locus_tag="IVW63_002626"
     CDS             4232..5047
                     /locus_tag="IVW63_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HAP7860858.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKKIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            5115..5825
                     /locus_tag="IVW63_002627"
     CDS             5115..5825
                     /locus_tag="IVW63_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7860859.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYVMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            5861..>6988
                     /locus_tag="IVW63_002628"
     CDS             5861..>6988
                     /locus_tag="IVW63_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAP7860860.1"
                     /translation="MKQVLRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         2365 a         1097 c         1407 g         2119 t
ORIGIN      
        1 acgattgtcg gcatccacca taaaagtgcc gtcatcacac tcgttgagcg actttcaaaa
       61 gccattatcg ccttgaaacc agaaggccgt aaggcagttg atattgaaaa ttcgattaat
      121 gaatggcttc aatccgtacc caaaaatctt ttcaaatcaa ttacctttga ttgtggaaaa
      181 gaattctcta attggaaaag tattagtaat acgaatgata ttgatattta tttcgcagac
      241 ccaggaacgc cttcccaacg gggattaaat gaacattcaa acggactcct ccgaaaagat
      301 ggactaccaa aagaaatgga attcaaccaa gtcaatcaag gattcatctc atccgttgcg
      361 tccaaaagaa accatatccc tagaaaatca ctaaattacc aaacaccatt agaagttttt
      421 ttgagttacg taaatggaaa gttttgtctc gcttaatttg acaaataata agccaataaa
      481 acttagtccg atatgcggcg cgttctgtgc gccgcatatt tttttagttt tcaaagatca
      541 gaccttgttg taaatagatc cgtgcccgaa agttataaaa gttgcgataa ccaaacgcaa
      601 ttcgtttaat cagcttgatc ttgttataca gcccctcagt gacgccgttt gagtgggaca
      661 ccttaaaggc atttgaaata cccgattggt agcgatggaa gatcgtgaat ttctttttaa
      721 acgactgagg taacgtagat gaaattgttt taagggtttc ttgaaagcct accgtatctc
      781 gtttaacgaa ataatagcgt aataattgac aaaaatgata cgcagttcgc aattcttcgt
      841 tgtagcttaa cagctcatta acgatttctg tttgactaat tggtcgttta aacagtcgat
      901 gataatgccg tttgagtgcc tcccatgtcg tggaatcttt gagtaagagt ttccaatatc
      961 gcttgagccg acggtacttc ttctgatttt cagagtgtga ggttcgaaaa cgattcatga
     1021 tctggacacg taattgattg aagctgcgat tgatgtgttg gacaatatga aagcggtcag
     1081 ttacgatctc cgcatttgga aagaccgttt taagcaactg acaatagctg gcattcatgt
     1141 ccatcactag gtacttgacc tttaaacggg cctttctagg aaagcgcagg aagtattgag
     1201 ttagtttgta aagtctgcga tcttcaaggg tcgtaaatag ctgattggtt gtcccatcaa
     1261 cacaaataaa actcatggaa ccagaagtgg caacattgtg tacttttctt tgcaatcttg
     1321 tgtacaaaac tattgcaaaa cacagcgcat aagaatcctt acaaaacagt agatgaagca
     1381 acccaattag atcttgttat agttgttaat cagctcttaa cgggttacga ttcaaaatgg
     1441 gtcaacaccc tatacttaga taagtcactt gaatatcaga acataattca ggctttttca
     1501 cgcacaaatc gtcttaatgg tcctgaaaaa ccgttcggaa ccattcgtta ttatcgtaaa
     1561 gcacatacga tggaacagaa cattgaagag gctattgagt tatactcagg caaacaagca
     1621 aaagggttat ttgttgaaaa attatataat aacttagaaa agttgaacga tatattcgaa
     1681 gaaattaagt ccgtatttaa tatttctggc atagaaaact tcagtcattt accggaggtt
     1741 ccaggggaaa ttaagcaatt tgtaaatctt tataatcaac taatccattg ttatgaatca
     1801 gcgatgatac agggattcac atgggcaaaa tcgacttatg aaatccagga ttatgaacct
     1861 ataacagtag taatcacaga atatgaattt aatatcttgg cacaacgtta cagcgagata
     1921 gagagagaac ctagagacgg aaatgatagt atagcgtatg acattgatta ccaattacct
     1981 gaaggtagtc gtagtcgtat taattatgag tatttaaaca caaacttcaa aaaatacatg
     2041 aatataaaag aagaacgtga ttcgaattta attcaatcat tgttaaacga cttacatcgc
     2101 acatttgcgc aattaccagt ggagttacag ccatatgctg agatgattct aaatgatgta
     2161 aataatgggg aattagttat caaagaagga tgggaattta ctgattacct caatgaatat
     2221 cagcttagtg aagaggacga ttttatccaa gatttagtgg attcaaccaa tattaatgag
     2281 gcattattac gtgagatgtt ggatttacgc ttaaccgagg taaacattaa tgaatatagt
     2341 cgatttgata aattaaaatc aagtgttaac gtaggtcatt tcagtggata tatcgagaaa
     2401 aatttaggta aaatggtaat accaatcaag gtaaatatgc taattgacag attattgcgt
     2461 gcatttttat tagaagatgt attcgatgtt acagagtaca taaagaatta ctttaactag
     2521 agtacaccta catcttatag tacataaaaa aattcatctt ttttagttta ataattcacc
     2581 aaaaaggtga gtaatgccat ttttgaaaat tgagcttgtt ttatgtctac atctgtatcc
     2641 gtatataatc caaaggatta taaactcaga agagtcttta ttttttctga atataactac
     2701 tgtatcaaaa acaatcgatt atgagacaaa acaaaatgac ctcttttatt taagaaagga
     2761 ggtcattttt tgtatcataa attgtattaa aatcaatgta tcacttttta atcaatttta
     2821 agaccataaa ttgcgtacta aaagaaattc tgcaattcaa aataaagcat tttaagccat
     2881 tttcaaattt aagtgcaccc atctacccgt caaatcactt tattttccac tccagtagtt
     2941 tcctaattca actgtgtgca aaacgatttc ttctaaacaa atcaagacaa acttataaac
     3001 cttcatccca gcaccataat tatttaaatc ataggcattt ttcgaaatta gtatatgtac
     3061 tcaagtttca ctgcagatta tttatatttt ttagagaaat aaatttttcc tattgacaaa
     3121 cacaaagaaa gcggatacaa tacaattatg tcacatgacg ttatatgacg ttatgtaata
     3181 tctttacatt taatcagtta cttttatttt ggataaaatt aacattttta aaattttaag
     3241 gaggaaatgt tgatggatgt agcaaaaacg gttaacgcaa ttgtagaaaa aaatgatgga
     3301 gagatttctg gaatttattt ggtggcttgt ggcggttcgc tggtagatat gtatgtctca
     3361 gattattttc ttaaagccga agcatcgaag tgtattacag gcttatatac agcgaacgaa
     3421 tttaaccatg taaccccaaa gcaattagat gataaatctg ttgtcattct atgttctcat
     3481 ggaggaaata cagcagaaac ggtaaaagca ggagaagtcg ctcaagctag aggagctgtg
     3541 actgttggtc tgactcataa taaaactgcg gatttattaa aggtttctga tcatagtttc
     3601 ctttacgaat ggggagatga tgcaaaaata gtcaataatc ctatggccat cattcttgat
     3661 ttaactgtat ctttggtcaa tgttaccgaa acatttgaac attacggtaa attcagagaa
     3721 ggcatgaagg ttatcgatac cgtaattgaa aatggcatta agcaggtgca ggatcgtatt
     3781 aaagtgtttg ctgataagta caaagatgaa acaatgtttt atatcttagg tagtggacca
     3841 tcatatggac atgcttatgg tttttcaatt tgctctttga tggaaatgca atggcttgat
     3901 tcaacttctg ttcattctgg agaattcttc catggacctt ttgaagtaac agacaaagat
     3961 acgaatttta ttctcttgat gagcattgga cgcactcgtg ctttagatga acgggcaaaa
     4021 cgattccttg ataaatatgc agaaagagta gaaatcgttg atgcaaagga actaggattg
     4081 gatatgatat cagatgaagt ttctgaattc ttcaatccca ttttattcta cagtattctt
     4141 tcagaatatc gttcagcttt agcagatgca cgcaatcatg atttagatgt tcgtcgctat
     4201 atggggaaag tggagtacta ggaggattaa aatgaaggta ttaggcttag gtgataacgt
     4261 cgtcgataaa tatgaaaatc tgggaattat gtatcctgga ggaaattcat tgaattttgc
     4321 agtttttgca aaaaaactgg gacatgaaag tagctttatg ggagtttttg gctcagatga
     4381 ggaggcagct catgttttat cagcaataaa aaaaatagga ctggacaaca gtcactctcg
     4441 ctttgaaaaa ggcgagaatg gctgtgccag agtgaagatt gatgagggcg accggatttt
     4501 ccttggcagc aattcgggag gtgttactcg tgaatacccg attcagctta ctgaagaaga
     4561 cagagaatat ttaaaccagt ttgaattgat tcatatggga ttatatagcc atgtcaatca
     4621 tctattagaa gagttacaaa atgtttctgg aaagatttct tatgattttt ctgacgactt
     4681 tacggaagaa gaggttcagc gggcaattga taaagttgat tttggcttct tttctataga
     4741 agacttttcc gatgaagaag taaagcagtt tttgatgaag catttttgtg agcgaaatga
     4801 tgtattgatt gcaacccgag gagaaaaaac ggctattggt tatgatggag caaagtttta
     4861 tgaagtgaac cccgtgctag aagaaccagt tgatacaatg gcagcgggag attctttctt
     4921 aacagctttc ctactttatt ttctcgaagg ggacgatata gtcaccgcga tgaaaaaggg
     4981 gaatgaattt gctgggaagt cttgtctggt tgacggttcg ttcggctttg gtattcatta
     5041 cgattgagct tgttttaaat tcctgcattt gataacctaa agaaagaaat cccggtaaag
     5101 tggaggttaa aaaaatgctg gatacaaatg cacaattacc attgtactta caattaaaag
     5161 aaatattaaa aaataaaatc aatacagggg agtatcccga gaatacgaaa attcccgctg
     5221 aatcagagct gatagaaagt tatgaggtca gccgaatcac agtgagaaaa gcagtagaag
     5281 aactggtaga agaagggtac ctacttaaaa aacaagggaa aggaactttt gtcaaccggc
     5341 ataaagtttt tcgtaaaatt gaatatgtta tgggtttcag tgagagttgt aaatctaatg
     5401 gttttacacc gactagcatt gttttggaac gcaagatcat tccagcaact gaagggatgg
     5461 caaaaaaact cgatatcgct caaggtgatg atgttttata tatccagaga aagcgaatgg
     5521 cggataacat ccccattatg ttagaaaaca attatttttc ttatgaaaga tatagtttct
     5581 taatggagga agagctgact gattctttgt atgaagtact taaagtccaa ggtaccttag
     5641 ccatcaatcc tggggaaact gcacttgaaa ttgtcacagc tgatgaccaa attgccaaaa
     5701 taatggaagt agctgttggg acgccctttt tctttatgga tactttaatc aacgatcaaa
     5761 acaacatacc aattcatgta ggtaatcaat attacctggg agaagtatat cgtttttact
     5821 tatgatttcc tgttttgatt tcaaggagta gattttattt atgaagcaag tattgcggtc
     5881 aaaaatgatt tttgatggag agcagccacc tttcaaaggt tatattgtaa tcaatgaagg
     5941 gatcattgaa aaggtggaaa acaactggaa ttacagtgat ctattaaatg aaaacacgga
     6001 attaattgct tatgatgatc aattcgttat gccagcaatt catgataatc atgtattttt
     6061 cagtggttat ttggctatga atgctggcat agatttaagc gatacatctt cagctaacga
     6121 ggctgtagag cgtattaaag ctgtaatgaa ccataaaaaa gcagatgaac caatttatgc
     6181 tcatggctgg gatgctgccc tgtggaaaac tgacccatca gaagagctat tgaatgaaat
     6241 aaaccacttt ggtccaatca cagcgatcga caaaaatcgc agccattgtt ggatgaatgc
     6301 tattgctaag cagacttatg gttttacaga aaaagaaacc agtgctgaaa gtcgagtatt
     6361 attaattaag gaaatgctag caaacaaaaa gcttttagca gaggtttacg ctgaatttga
     6421 agcattactg ctttcaaaag gtgttatatc aatgaaagaa atcgtttttg atgacgcaga
     6481 atttctttct aatatacctc agaggaaaat acttagtaac ctatatgtgc aggcagtcca
     6541 agaacctcta cagcatgaac ttctatatga gtataaggaa aaagttttcc ctgaaaaggt
     6601 ccgctttggt ggagtgaaga tcatggtaga tggtgttgtt gcggatagaa gtggagatat
     6661 ttacggtgtt tatcagtcag gagtagcttc acccgagatt gactatgagg caattaaagc
     6721 agaagttgct gcattcaatg aagtagagat tccttgctgt ttgacaacgg aaggagataa
     6781 agcgggttat aaagctgcgt caattcttgt cgaatttgga aagcggttac ctgaaggcgt
     6841 ttttaattcg attagtgatt tggaaatggt tactcaaaag acagcagaaa aaatgaacga
     6901 aggacaagta gtagcagagg tatatccaca aattctcggc ttgaatcaaa cgttagaaga
     6961 ggcttacatg tcaactgtta taaaaaat
//
LOCUS       DACCVZ010000117         6905 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.120, whole genome shotgun sequence.
ACCESSION   DACCVZ010000117 DACCVZ010000000
VERSION     DACCVZ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.120"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..182)
                     /locus_tag="IVW63_002629"
     CDS             complement(<1..182)
                     /locus_tag="IVW63_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP7860861.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="IVW63_002630"
     CDS             517..951
                     /locus_tag="IVW63_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP7860862.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="IVW63_002631"
     CDS             974..1294
                     /locus_tag="IVW63_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860863.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1435..1626
                     /locus_tag="IVW63_002632"
     CDS             1435..1626
                     /locus_tag="IVW63_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860864.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(1697..1954)
                     /locus_tag="IVW63_002633"
     CDS             complement(1697..1954)
                     /locus_tag="IVW63_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAP7860865.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            2112..2375
                     /locus_tag="IVW63_002634"
     CDS             2112..2375
                     /locus_tag="IVW63_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860866.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            2399..2587
                     /locus_tag="IVW63_002635"
     CDS             2399..2587
                     /locus_tag="IVW63_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860867.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(2670..2855)
                     /locus_tag="IVW63_002636"
     CDS             complement(2670..2855)
                     /locus_tag="IVW63_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860868.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            3070..3441
                     /locus_tag="IVW63_002637"
     CDS             3070..3441
                     /locus_tag="IVW63_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP7860869.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(3591..3663)
                     /locus_tag="IVW63_002638"
     tRNA            complement(3591..3663)
                     /locus_tag="IVW63_002638"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3628..3630),aa:Gln,seq:ctg)
     gene            complement(3709..4137)
                     /locus_tag="IVW63_002639"
     CDS             complement(3709..4137)
                     /locus_tag="IVW63_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860870.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(4197..4955)
                     /locus_tag="IVW63_002640"
     CDS             complement(4197..4955)
                     /locus_tag="IVW63_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HAP7860871.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            5250..5447
                     /locus_tag="IVW63_002641"
     CDS             5250..5447
                     /locus_tag="IVW63_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860872.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            5553..6035
                     /locus_tag="IVW63_002642"
     CDS             5553..6035
                     /locus_tag="IVW63_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860873.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(6093..6689)
                     /locus_tag="IVW63_002643"
     CDS             complement(6093..6689)
                     /locus_tag="IVW63_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP7860874.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
BASE COUNT         2340 a         1060 c         1356 g         2149 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt tggtataaca
     1621 gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc gttttctttt
     1681 taaacatgcg agggattcaa ttctgattct tatataaaaa atagatccaa ataataagaa
     1741 aaattactga aagcgtcaat tcgatgatgt gtgttattaa tacagacgtt gtttcccaat
     1801 gcctaaaaga aaaaatttga taagtaaaat atacagcagg taaagaggcc agtaaaactg
     1861 aaaacttctt ttttgtccat tttatgtaat agaaaagaat gcttatcata ataaaaaaag
     1921 gaatataaaa aacaaattga ccgatcgcga tcatactatt gcctccgata aataaagtcc
     1981 atgatacaaa ataacacttt gtgcgaaatg gcgcaagcag ttttgtggat ttatccggta
     2041 aaatctgtat cgattttgaa attagaggag aaacttgcta taatcaaagt gaaagaagga
     2101 gtgggatttt catggatcat gtagtgttag aaatcgattt gcatttgatc aataatattc
     2161 gggtgattta ctatgttgta agtaacagtg tcgaacaacg tgtactgacg aataaaataa
     2221 atggtatttt agcaaagaaa gacgttcacc gattcaataa tggtgaagga agttattata
     2281 gtatcccagt agaaaaaatt atttatacga cagtcaaagt cagagaagat ctagatacca
     2341 aaaaagcata tgaacctatt tttacaactt attgattgac agcagatgga ggaaaaaaat
     2401 gaatccatat gaacaactta ttcaagattt gatcgatgga aaaatcgaaa agattgatgt
     2461 aaaaagagaa gaattaatgg cttttcgaga agcgtggctg aagttggaga atcgtaaata
     2521 tgtggtggga aaagcctcac tgaacggcaa tgtgacttat cattacgatc cgacacgttt
     2581 attttagtat gaagtattca gaaaagaacc aaaggaggac gatgcagcag cattgtcctc
     2641 ctttgatttt acaaaagtga aagttttact tatttgaata gatttttaaa tttgtttttg
     2701 acactgtcga tatttacatc ttttaaaaga ttttgggctt tctctttata aggtcctaat
     2761 tgttctttat gttcttcgat aaatcgtttt gcgccatcga aattgccgtt cttaatcatt
     2821 tccttgactt tttgaaataa ttcttcttga ttcattttga acacatcctt tgctatcaac
     2881 atgatttttt acatggacaa aacgagaaaa actgatttat ccacacgtca ataatatcaa
     2941 ataacgatca tttttactaa aaaaacactc gattctcgct tctaaagtag gagaaaaatc
     3001 tccaacttgg gacggatgga atttctttaa ctgacccata tactgaatat ataacaagga
     3061 ggtagaaaga tgaaagtgat taaatatttg attggactgg cggcgattag tggtattttg
     3121 ctatttggac tgaaatatta tactgaagga agttatggag aaatccctgg tatacttgat
     3181 cagctaaatc cattagttga aaaaggagag gtctatgtaa agacacaaaa accagaggaa
     3241 gtaaatgaat atggtacagc aaggtatgtg cagaaagctg ctgatgccaa tgggaaagaa
     3301 cgaacggttg aatttaatgg tctttctgtg ttaaaagaaa atcattattt gaaaattagc
     3361 aataaaggag cacacataga aacgtatgag gaagttccta gagaaaaagt tccggagaaa
     3421 gcattagcaa ttattgggta aatcagtttt tgtattaaga atacgcccga ttttattatt
     3481 cataatttaa ttatgtaaac taaatacaag tagtaaaaat aatacaataa tccccctgca
     3541 aaaagattgt tcttttacag ggggttcatt ttttcagcaa gcacatcaaa ttgggatggc
     3601 agggttcgaa cctacaattg cttgattcag agtcaagtgc cttaccagtt tggctacatc
     3661 ccatttattc aacaaaataa tcatagcact ttcctaaaaa aacgcaagtt atttttcttg
     3721 atcggatagt tgttgcttta ctcgtaaaag gcggcgtact agtttctttt ctaatccagc
     3781 aggaagggca atcagttctg ctactgacaa gacggtgtcc aataactgat attctttgac
     3841 aggttcattc ataatatgat agatgtttgc taaacgttca atatattcaa agcgagtata
     3901 ctctgttcga gcaattagaa atttcaataa atcggtggct ttctcgtact cttgatctgc
     3961 gtaataaaca agagattgac gatacaattt gatttccagt tcattgaggg tagcaggtct
     4021 gcgacgctcg ttccactcat taatagagac tttaccttga acatttccct tgcagtcacg
     4081 gacaaaaata atcggaattt catttggatc cattttttta tgtgtgaatt tttccattat
     4141 ctacgctccc ttcaaaggtt tggtatcttg agtataaggg atttttgttt gaattactag
     4201 cttttctcca aagttagcat ctgtccaccc attgcagtga aaatcgccga aaaatcgttg
     4261 atcggtactg ctcgattttt tacaccatag ggatcgttga cataaatatt ttctttgtca
     4321 tatccagtga ctacacaagc atgaacaaga ggagtgactc ttacttctcc attatttgtg
     4381 gtccaagtca taaaatcagt ttcatctggg acttcaaaat tgatagtcac agaagtccag
     4441 acaggatttc ctttagatag tgcttttttg atatcatcga gttgagcatc ggtttttgga
     4501 aaagtgtgat aatccgtttg gacgatttgc tgagcaaggg aggcaactgg gggaacatag
     4561 acgaccatag cccagtctcc gccactgata tcaccaacaa atccttcatt aggatcgcca
     4621 tgagtcccat ctgcattgaa aacagggacg taatccaatt gctcagctaa ctggttttta
     4681 gttgtttcat aaccataaaa agataaaagc atagaaagcg aagtgacttc acagccattt
     4741 tctaaagaag gagaatcaaa ctggctctct aatggaacat ctagtaaaac ttctgctttc
     4801 tcttttgtct ttttcgtttt ttgtgttgaa cttttttgtg cagtgttcat tgtatgttct
     4861 ggagaatgga tatgtaggta ataacttgta ccgcttaata aaagagcagc tgtgccccct
     4921 agaaacaata gttttttgaa cgtttttttc ttcatttgaa atctcccttt tcagctgttt
     4981 atctttccta ttataaatgt atttttattg gaaatggaag tattatattt taatatgtag
     5041 gaaataatta gtttttaagg aatatgtttt aattttttga aaaaaattct tctaaataca
     5101 acagctgttt taattgtgaa aacgaaaaca gtacgctata atgcctgtaa ggttgatttt
     5161 taactgtaaa taaaaatcaa tgagttaaat ctccaaagaa atagcagtgg taatgtggag
     5221 aaaagttcca gcagtttagg aggattttga tgacggaaga aatgattaat ttaggagaac
     5281 aatatgcatg caaaccaatt ggttttacaa aaacggtcat tggtgaagtt gtatcaaaaa
     5341 tgacaaactg cgccgtggtc aaagttgccc aatgtgctgc agaggaccaa gaattattag
     5401 atgaaaaagc aagcatggtt gttgcaaaat atgatacatt tgaataaaga aaacaattgg
     5461 acgtgcggcg tgctgcaagt ccaatttctt tgagaaggta aatcagtatt cttttcctat
     5521 tttctggaga agaaaaagcg aggcgagttg tcatggtaac attctttacg gttctattgt
     5581 ttttattcgt tgttgtgatg tttttatttc tttggctggt tcgaaaagaa attatttatc
     5641 ggactgtgcg aaatcgatgg gtctacttgg tgataccctt cttagtgtca ctagtcattt
     5701 ggtatacact catcagtcat cctacagcag atgaattggc aaaagggatc ttgtcagcaa
     5761 tgatttttat tagttttttg ttggacagta gaggaatcac agaagaagga cttgttttga
     5821 atagctttga caaaaaaggt gttccttttt ctgagatcaa taaaattgta ttatatcagc
     5881 caaaaggttc taaaatcgta aaaatgaatt ttttccgaaa cggatggcga ggaccgatgc
     5941 tgaaattttc tgcatcatta gaagaattag ttccattttt gtcccaacgc ttaaacgatg
     6001 aggcagagat tgatattatg attgatccag aataaaaaca gaggttgcga caagatgttt
     6061 gtcacaacct ctgtttttta tttcaaataa aattatccaa atacgcggaa gcgatcggca
     6121 tcgttcatgt attctttttc ctcagccggt gtttctggtg aaccgaatac taattgcgaa
     6181 cgtagtttcc agtttgaagg gatattccat tcttttgcaa ctgcttcgtc aataactggg
     6241 ttgtaatgtt gcaagtttgc gcccaatcct ttatcaacta atgctaccca agtattagct
     6301 gttgcgattc cgtttgattg ttctgaccaa tctgggaagt tgtctgcata taattcaaat
     6361 tgttcttgta gaccttttac cacgtcagta tctttgaaga ataatactgt accataacca
     6421 tttttgaaac cagctaattt gttttgtgta tttgggaaag cttctgctgg agtcaatggg
     6481 cgaagtgctt cttcagtgat ttcccaaagt ttttcatgtg catctccgaa aaggataact
     6541 gcgcgtgttg attgagcatt gaaagcagtt gggctttctt taattgcttc tttgatcaaa
     6601 gttgttaatt cttcattaga aagtgaaaca ttacgtccta gatgatagat tgaacggcgg
     6661 tttttcaaag tgtcagtaaa agttgtcata ataaaatttc tcctttgatt tgcgttttgc
     6721 atttttttaa ttgattacga aatgaagtat agcaccttac aaaaagtaag taaacagata
     6781 tgctcacaaa aaataagcga agttcaaaaa acaattttaa taagaaaaat cgttatgtaa
     6841 ggattttctt agttatcgct ttcattgttg tgttttagga atttttgctt atttgaaaaa
     6901 aacag
//
LOCUS       DACCVZ010000118         6860 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.121, whole genome shotgun sequence.
ACCESSION   DACCVZ010000118 DACCVZ010000000
VERSION     DACCVZ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6860
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.121"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            560..754
                     /locus_tag="IVW63_002644"
     CDS             560..754
                     /locus_tag="IVW63_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860875.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            945..1194
                     /locus_tag="IVW63_002645"
                     /pseudo
     CDS             945..1194
                     /locus_tag="IVW63_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1438..2268)
                     /locus_tag="IVW63_002646"
     CDS             complement(1438..2268)
                     /locus_tag="IVW63_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAP7860876.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            2476..3810
                     /locus_tag="IVW63_002647"
     CDS             2476..3810
                     /locus_tag="IVW63_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP7860877.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            3851..4762
                     /locus_tag="IVW63_002648"
     CDS             3851..4762
                     /locus_tag="IVW63_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP7860878.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAVSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            4759..5613
                     /locus_tag="IVW63_002649"
     CDS             4759..5613
                     /locus_tag="IVW63_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP7860879.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            5610..6227
                     /locus_tag="IVW63_002650"
     CDS             5610..6227
                     /locus_tag="IVW63_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAP7860880.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            6229..6747
                     /locus_tag="IVW63_002651"
     CDS             6229..6747
                     /locus_tag="IVW63_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAP7860881.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
BASE COUNT         2052 a         1187 c         1377 g         2244 t
ORIGIN      
        1 aagtttgttt ttcattgtat tttttgctgt tggttatttt ataataaaga tatgatgact
       61 aatttagctc aactattcca gcgtcagctg aagatattgc aattcccgat tccttaatca
      121 tttatctgga tgagacagaa agtgaagttg caacagatgt gcatgtagtt gaggataaaa
      181 atgatagttt aaaaattaat agttcagata ctttactaag agtaagtcct atcttttcag
      241 ctgttattta gatgcaagta gcaactaagt taggtagtac tcctgcaatg gataggtatt
      301 tgtgtgttcg atatataagt ggtcgaagta tcaaggttat gtatactgga tgggagatag
      361 aagagttaaa aattggaggt caccgccaca aatggaattt agatttagag gtaccttaga
      421 tttggtatag ttattaaaca caagatggcc tggtttgtag ggaaagtcga agagtatttt
      481 tccacttctg cgccccttta atttttctag taatgccgtg aatttgtgat taattggaaa
      541 tatgaagaaa ggagagtcta tgaaaacaac actagttcta ttctataaaa agcatcctta
      601 ttttacactt ctgataaata tattgttggc tagtgttatc gggatttctg ttgaatatct
      661 aataaataaa gatttcatag gttcttgttt ttatacggct ttatttcttg gacttcttga
      721 agcattttcc atttataaaa aatcaaaaaa ataaaataga ttgccgtaag agatcttttt
      781 catttcattt ttttctgaaa acccgttgtt tctgtcagtg aagcagcggg tttttagatt
      841 tattgtcttt agacctaatt gagcgcgccg agcgattgaa atacaaaacc acttgctatg
      901 cgggtggagc aataaaggga aatagtttag cccgtacaaa gtagatgtgt aaataccaca
      961 ttgtattcac accaaagtat agaagaaaaa taatttataa tcaatatcga gccaatattc
     1021 aggagatcat caagagattg tgcaaatcta aaatataaat ttgggtatcg acacttttgg
     1081 gtggaaggat actatgtgac aaaagtagga caaaatgaag cgaccatcaa aaagtacatt
     1141 caagaacaag aaaaacatga tagtgcgtta gataagctga gtgtacgaga gtaagacgat
     1201 ccttttaagg gctaaggagt agtacataaa ccttttaaga ggtgggcaaa actggcaaag
     1261 gcaatatggc ttgaacataa aatatgaaag ccagcgtctt taggcgctgg ccggtgattt
     1321 gagcttatag ctctagagaa aaccaccctt ttgaagggtg gttatgatta atgactttag
     1381 tcagttttgc tcacaaagcg tgtggaacaa aaaacgggtg tttctacggg tagatattta
     1441 tttcttgaat ggaggtgtcc catacatttt tggtgttact ggttctaatt ttggtgcagc
     1501 gccttcgatc ttaggttctt tcaaccattg atattcgcct tcgccatcca gtgctttgcc
     1561 actagcccaa gaaccttcac tactttggtc tccctctgag aagttataga agtcataagc
     1621 aatgtctttt cgttctttgt cacgcgggaa agtacttggg actaagattg aaccttcttt
     1681 ttcttctaat tctttcactg cacattccca tagattttga tgatagctat ctcttgcaag
     1741 gagaacagac agcatatctt ttacgccacg atcatcgatc atttcgtaaa tacgtgctac
     1801 ttgaagtctt ccttgtgatt cggcatttaa attagctcta aagtctgcta acaagttgcc
     1861 actcgcaatg atataggcac cgctccatgg attgcccacg ctgtcagcag gacgaggtcc
     1921 taagccagct acgatcgcgt gctgtggatt cattccagag ataatggcac cgattgttgg
     1981 atctttttgc atcgctgctt cttgatcttc aacaggcgca ccctctaata aacgagcaac
     2041 cattgtcgcc aacatttcca cgtggccgat ttcttctgtt gcaatgtcca tcagcatatc
     2101 tttatatttt tcttctcctc ggcagctcca gccttggaac aggtactgca tagctacact
     2161 catctcgcca tattggccgc cgatcagctc ctgcagatat ttcgcgatta atggattcgg
     2221 acgatctggt tttgcttcaa actgcaattc tttctggtgt ctaaacatca aaattcctcc
     2281 taatctattt ttaatacatt ctcattctgc tacgaaagat taaaaaattc aaagaaagcg
     2341 ctcgcgaatt atataaagta ttggtatcat taataatttt tttagaatca taccttataa
     2401 attgttattt tcagaacaaa atgatatcgt tatattaaaa ccggcatcgg ttacattaaa
     2461 atttggaggt aaaatatgaa aaaattattg tttacagggt tgctggcaag ttcagcattg
     2521 tttttattag gaggatgcgg atcaagtaat gcaagcgatg ccagttcaag tgcagcaaat
     2581 tcttctgaaa aaacaagtga tggaagaaaa aatattgatt tctggtcctt ttggggatcc
     2641 ggtgcacgaa aagaagctat cgaagaaatc attgaggatt tcaatcaatc acaaaacgag
     2701 atccatgtaa attataagta tcagccatgg ggtgacatct ggactaaatc tttatctgca
     2761 ataacagctg gaaatgcacc cgatgttatt gtacaggaca taaattccgt tgcccaaaga
     2821 gcagaagcac agcaagcaac taatctctcc aaatatgtag aaaaagacac ttctaaggat
     2881 ttttatccgc agctttggga tacagtagaa tatgaaggtg atccttatgc gatcccattc
     2941 aatacagata cacaagtcat tttttataat aaaaagttat ttaaagaagc tggaatcagt
     3001 gaacaagatc taccgacaac ttgggatgaa ttagaagaaa cagcacgtaa actagataaa
     3061 aaagaaggaa aagaatttac acgcatcggt ttttatccat tatggaattt aggggctgat
     3121 gtatgggcgc taaacgcaga taacgggact agttggtttg acaaagatga aaaagtcaag
     3181 attgatacta aaaataaagt ggaagccttg gagtggatcc aagactggca agattattat
     3241 gggaaaaata cgatcaataa attagaagcc gaatttgggt ctggtgtatc tgatccattt
     3301 atttccggat tagtagccat gcgtgcccaa aatatcaatt attactctag tttgatggaa
     3361 aatgcaccgg atgattttga ttttggcgtg atgcagctcc cagaaaaaga agaaggttca
     3421 ggccattggt cgtggggtgg cggattcgtc ttggaagtac catacggagc aaaagatcct
     3481 gaggcctctt atgaattcat caaatatctt tcttctccag aagtacaaga aaaattcggc
     3541 gaaaaaagtt ttgatatcat ggcgagcaag acagccaatg agaatttagt gaataatgac
     3601 aacctaacgg ataaaggaaa aatgatctat caaatggcgg acgaaaactt taaaaatacg
     3661 gtgatcacac cagttccttt agatgctccg gattacacga cattagtgaa tgaacagatt
     3721 gaccagattc ttttaggaac aaaatcacca aaagaaggat tggcagatgc acaaaaagca
     3781 gtagaaaact tagtcaagca aaatcaataa tccatttttg actgtctagg tacagaggag
     3841 gcaagaaaat ttgaagcgtt tatctatccg aaagaaaaaa gaagcaagat gggcctattt
     3901 atttatctcg ccttttatta tcgggttctt ggtatttatg ctagggccta tgcttttttc
     3961 agttattggt agtttcaccg attataattt gacatccaag atgaatttca ttggtctagc
     4021 aaatttcaaa agaatgttcg ttcacgatga tttattttgg aaatcgttat acaacaccgt
     4081 ttatttcgtc atcttcaatg taccgctgac gacgattttc agtgtgtttt tagccacagt
     4141 actcaatcaa aaaatcaaag gaatcagtgt attccgtaca gctttctatt taccggcagt
     4201 cttatcagga gtagcagtct acatcttatg gatgcagctg ctttctccat ctgcaggatt
     4261 gatcaacaca tttctgggct ggttccatat ccctggacca gcttggctgt ttgatccaca
     4321 atggacgaaa cctgcgttga ttttgatgaa aatatggagt tctggaggag caatgctact
     4381 ttacttagct acattacaaa atgttcctag atctttatat gaatcagcag aaatcgatgg
     4441 agcaggcgtt tggggaaagt tcaaaagtat tactttgcca ttaatcactc ctattatttt
     4501 ttacgatgtg atcacctcta cgatcggttc tttccaaatt tttcaagaag cttatgtcat
     4561 gacgaaaaat ggaacaggcg gacctgcaaa ttctttgctt ttttataatc tgcatatgtg
     4621 gaacaaggcg ttcgtagctt ttgatatggg ttatgcgatg gctgtgtcaa tgatcctgtt
     4681 tctgatcgtg ttggttctga cgtttgtcaa tttgaagctt gcacctaagt gggtctatta
     4741 ttctggaggt gacggcaaat gatggattat ttcaaaaaga ccagtgtgaa tcggcaaaca
     4801 aaaaaaatac taagttatgt cctcatgaca gtaataggaa tcattttgat cattccattg
     4861 ctttggatgg tgtttacttc attgaaacca atggaagaaa tcgttcgtta tcctccgacc
     4921 tttttcccag aaaaaatcgt atgggaaaac tatctggata cgattgccgc ctttcctttt
     4981 tggcgctatg caagaaatac attattcatc actgtgctag tagtgatcgg taatgtcctt
     5041 tcaaattctt ttattgctta tggatttgcg aagcttgatt ttcctgggaa aaagctgatg
     5101 tttgctttgg ttctttctac gatgatgatc ccggggtttg taacgatgat ccctcaatat
     5161 gtattattct ccaagatcgg ctgggtaggt acttatttgc ccctgatcgt tccatcgttc
     5221 ttcggcaatg cgttcaatat atttctgatg cgtcaatttt acttatcgat caataatgaa
     5281 ttgatcgaag ctgctgaaat cgacggagcg aatcatttgt atatttggag tcatttgatg
     5341 cttccattga cgaaacctgc cttgattacc attgcgatca attccttcaa cgcagcttgg
     5401 aatgatttct taggtcctct gttatatatc caagatcaag aaaaatacac gttacagatt
     5461 ggcttgcaag tttttcagaa ccaagcaacg acacaatgga attatctgat ggcaggagca
     5521 acacttgtct tgatcccgac gattttgctg ttcttttttg cacaacgtta tttcattgaa
     5581 gggatggatt tgacaggagg ttcaaaagga tgatgaatcg atcgattggt aaaaaagcca
     5641 atgattattt cttagaaatc attgaatgga ttccacgtct tatccattta cagctactat
     5701 ggttcctgtg cgtcttgcct gttttcacat taggaactgc aagtcgaaca gttctgtata
     5761 tgatttatca ttacaaaaaa aatgaagaga aaaagctcgg ttcactattc tggaaaaagt
     5821 ttcgtgagaa cttctctctt tatggaaagc aagatagttt agcaagtgtt tattttcttc
     5881 ttctattgat cgattatcag attttccgct attggggtgg gggaattggc tatacattga
     5941 tgtatactac gttgtttttg cttctattaa gcgcgcttct ctttagttac aaaatcttgc
     6001 ttcaactgga acaaaaagaa gcttcttgga ttactgcatt tttcttgttt tttaatgatt
     6061 tcaaaagcgc gcttttctat ttggcaggca cgttgatcct tcttgtcgca ttctggtttg
     6121 caggaccaat ctattttgct ttattaggtt tcagtttctt gttttatttt caagtcctgc
     6181 tttttatcca tcgtacgcaa gaaaaggttc ttaaaaagga ggaataacat gttgcgtttg
     6241 attgctaaaa tcgatgatag tattatcaac aagttcgcca agcaacggaa aacggatagt
     6301 cgaaaaatca attttttgaa atttatcagt aatatctcta atggtggttt tatttggttg
     6361 ctccttgctg ctgttttagt cttgatacct gatactagag aatatggtct agccattctt
     6421 atcggcagtt tgatctattt ttttgttggt ttgcttttta tcaaaaaaac gacaagacgg
     6481 aaaagacctt atgaaaaaaa tcgtcggctt gtcctttaca caagtaaacc gaagacttct
     6541 tcttttcctt caggacatac agcgctagcc tttttatcag tagctgcgtt gttcgaatta
     6601 agtccagttg caggaatatt agccttttta tttgcttgtt tgatcgctta ttcgaggatt
     6661 tttttacttt tacattatcc tactgacatt ttaggaggag ctattttagg aagtgttatt
     6721 ggcatcctat gcgctgccgt tatctgaatt aattgtacga ataaagcatg agtgcgtaaa
     6781 tgcgcatttg tgctttattt ttttgtttcg aggaaagcgt agttgtttat tcatttgtct
     6841 taataactta agttttgtta
//
LOCUS       DACCVZ010000119         6780 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.122, whole genome shotgun sequence.
ACCESSION   DACCVZ010000119 DACCVZ010000000
VERSION     DACCVZ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6780
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.122"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            14..904
                     /locus_tag="IVW63_002652"
     CDS             14..904
                     /locus_tag="IVW63_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HAP7860882.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(977..1801)
                     /gene="nadE"
                     /locus_tag="IVW63_002653"
     CDS             complement(977..1801)
                     /gene="nadE"
                     /locus_tag="IVW63_002653"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAP7860883.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(1813..3285)
                     /locus_tag="IVW63_002654"
     CDS             complement(1813..3285)
                     /locus_tag="IVW63_002654"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAP7860884.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(3922..4284)
                     /locus_tag="IVW63_002655"
     CDS             complement(3922..4284)
                     /locus_tag="IVW63_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAP7860885.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            4507..5259
                     /locus_tag="IVW63_002656"
     CDS             4507..5259
                     /locus_tag="IVW63_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP7860886.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(5399..6322)
                     /locus_tag="IVW63_002657"
     CDS             complement(5399..6322)
                     /locus_tag="IVW63_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP7860887.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(6337..6609)
                     /locus_tag="IVW63_002658"
     CDS             complement(6337..6609)
                     /locus_tag="IVW63_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860888.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         2070 a         1351 c         1159 g         2200 t
ORIGIN      
        1 agaggtgata tatatgcaac tacaaataaa cgaagaatcc ttaccggtat atgaagcatt
       61 agctagtaaa acaaggatca agatcatcca gctactttcc aaaaaaaaga tgaatgtcaa
      121 agatttggca aaagaacttg gagtgagcag tgctatcacg acgatgcacg tgaaaaagct
      181 agaggaagca aacatcatca aaacagaaaa agtaggacaa caaaaaattt cgagccttcg
      241 tgtcgataaa atcgatatca gttttccaga aaaaatattc aatgcttttg atacgaaaga
      301 aacatcgata cctattggtc actatacaaa ttatgcaatt gaaccaacat gcggtttagc
      361 tacgatccat gattttatcg ggaaagtgga tgaaccacgc tattttatgg atcctcgaag
      421 gatggatgcc cgcattctct ggtttaccag cggatttgtc gagtatcagg cacctaattt
      481 tttaaataca gaggatacat tggagatgtt ggaagtttct gtggaaattt cttctgaatt
      541 tcctttttca aatgacaatt ggccttcaga tatcactttc agcctaaatg gtgtggagct
      601 aggaacatgg acgagccctg gagattttgc tgatatccgc ggtaaatata cgcctgattg
      661 gtatccagat aatcttaatc aatacggctt gctgaagacg atccgaatta ccaaacactt
      721 gacgaatatg aatggagaac ccttgtcaaa catcacgatc aacgacatcc ctaaagagca
      781 agacacttgg catttgcgaa tcgaagtgaa agacgatgcc aaacatgtgg ggggctgtac
      841 tttatttggt aaaggattcg gtaattacga tcaggatatc aaattaaaag tttactacag
      901 ctgatatttt tcttttctat tttataaaac aaaaacagcc aatccctatg aagggacggc
      961 tgtttttgct ttattgttat ttccagaaat catccaaaac ggaaattggc aaatgtcgtt
     1021 tatgttgtgt cttgttccac catgcttcga ttttttcttg tgcttgagcg ggaacttctt
     1081 ttccttctag ataatcatca atttcattat atgtgacacc tagtgcgact tcatctgcaa
     1141 tcattggttt cccatcttca agatctgcag tcggaatttt tgtgtataat ttttccggtg
     1201 cattcaatgc ttgaagcaat tgtttccctt gtcgtttgtc caaacggaat aatggcaaaa
     1261 tgtcggctcc accatcacca aatttcgtga agaatccagt aatgttttct gcagcatgat
     1321 ctgtccctaa tacggctcct gctctttctc cagctacggc atattgcgta atcatacgtt
     1381 gacgtgcttt gatatttcct ttgttaaaat cgctgattcc cacacctgct tcgcttaata
     1441 cttgtacttg tgcatcaaca gctggtttga tatttactcg cagactaaca tcgggctgga
     1501 taaagtcaag agcagctttt gcatcttctt catctgcttg ttcaccataa ggaagacgaa
     1561 cagcgataaa ttgatagttt tcatcttttg tttcttcacg catttcttcc atcgttagtt
     1621 gcgccaaacg gcctgctaaa gtagaatctt ggccgccgct gatacctagt acaaaagttt
     1681 taagaaacgg atattttttc aaatatgctt tcataaagtc aatactttta cgtatttctt
     1741 cttttggatc aattgttggt ttgacaccta attcattgat aatttctgtc tgcaggctca
     1801 tttattctcc tcctatgctt ctgtatgaag ttctgctacg ctttttttca ttcgttccat
     1861 gatagccatt ttatggttcc agcattcagt agacagatcg actgggtatt tttgcggatt
     1921 caagtctcgt ttatactctt cccatagtga atctagattt tcttttgtat attctttgat
     1981 ttcgtttagt gcaggtaatt cgtaaactct ttttccttcg ataaagatat cttgtaaaac
     2041 tgggcgagct gtaaagtctc gaacagtttt attgataaac gtatgcactg gatggaacat
     2101 gaagatagct tcttcttctc gagggtcttc atcccataat gtcacgtagt ctccttcaga
     2161 tttcccatca aaatttcgag tgatgcgcca cacttgtttt ttccctggag tagttacttt
     2221 ttctgcattg cttgataact tgatcgtatc catcattttt ccttcatcat cttcgatcga
     2281 tactagcttg aatactgcac caagggctgg ctgatcatag gctgtgatca attttgtccc
     2341 aacaccccat acatcaattt tagctttttg catctttaaa ttcaaaatcg ttgcttcatc
     2401 caagtcattc gaagcataga tttttgcttc cgtaaatccg gctgcatcta attgttcccg
     2461 aacacgctta gatatatagg ccatatctcc actgtcgatg cgtacgcctt ggaagttgat
     2521 tttgtcacct aattctttcg ccacgcgaat cgcacttggc acacctgatt tcaacgtatc
     2581 ataagtgtcg actaagaaca cgcagtcttt atgggtttta gcgtaggcca taaatgcttc
     2641 ataatcattt ccataagatt ggactaacga atgagcatgg gtcccgctag ctggtatccc
     2701 aaatatcttc ccagcacgta cattgcttgt tgcatctgct ccgccgatat atgccgctct
     2761 agttccccag actgctgcat ccagttcttg tgcccgtcta gttccaaatt ccaatagtgg
     2821 atcttctccg atgacagatt tgatacgagc tgcttttgtc gcgatcaacg tttggaaatt
     2881 gaccatattc aacagtgctg tttctactaa ttggcagtgc gctaaaggcc cttccacttg
     2941 gattaatggt tcatttgcaa aaactagttc tccttcacga gcagaacgaa ctgttgcttt
     3001 aaattcaaaa ttttgtaaat actccaaaaa accttcagga tagacttcta atccacgcaa
     3061 gtaagcaata tcggaatcat tgaacgtcag attctctaaa taattgacta accgttccaa
     3121 tcctgcaaaa accgcgtatc cgtggttaaa aggcatttct cgaaagtaac attcaaaaac
     3181 agcatgtaaa tcagctcgac ctaattccca gtatgtctgc atcatattga tttgatatag
     3241 atccgtatgc agcgtcaaac tgtcgtctgg gtaagtatta ttcatcttgt attactcctc
     3301 ttggcaagtt ttcatttcct acccattata acaaaaaaaa ttaataggaa aagaaatctt
     3361 ccattttttc tgaaaaagca catgttttac ggatatttct tgctaaaaat gaactccatc
     3421 tgctaaaact atcctttctt attggtattt aacctaaacg agaaagaata cttattttat
     3481 tcaatgtatc cgagacacga agaaattagc gttttctatt tttcttactt gataaaataa
     3541 gtagattttc ctactacaat cgtagccgtt aagataccga tgattgaaca aatataacca
     3601 aatgtctcta caacataatc aatggcaaaa gtttttgaag caataatacg tctttccttt
     3661 tttgcttctt atccccaaag aaacggatat aacttattat gtattgaatt tttttggaaa
     3721 ggcgaattat gacaagatat accttgcgtt gaaaaaactc gcggaaaaaa tatcacacgt
     3781 ttttaaaaag atacaaagta agaaagcagc tgtcaataga atggaaacaa aaatggcgag
     3841 acatcaatca gtctcgcctt gttttttatt gtatacatta gatatggagc aggttaccat
     3901 aaagatgatt attagtcgtt attaaataga atccttcgta tttttttgtt ctatcactac
     3961 aatatcttta tttggacgtt tgaattgtat tccggcacgt tctagctcct gtttcactcc
     4021 tacatggact ttgacatctt ctcgtgtcat ttttaaaacg tgatgaatcg catagtcgat
     4081 ttcttgcctt gtgatttttt tcttcgtatt gatcatcacg acttgctttt tatcatatgt
     4141 gtctaccaat agcagttgtg ttcgatctaa cgaaaataat ttgtaataat taatagccgt
     4201 attcccaaaa aagaattcca ctactttagg ataaaatgtc ttaatattta aattactatt
     4261 cacaggtgtt tcgattagct tcatctcatt cctcttttct atatagtcga tttagatcca
     4321 atcttaagtt atgttaccat ctttcctagc attaaggaat cggttacaat tgaaccttta
     4381 aagacaaaag gatttacctt ttatcactta atagtataac ataatttcgt gagaaaaaaa
     4441 tacaattttt tcttgaccat ctcgttacgt aaaggattat gcttacattt gtcaggagga
     4501 aaaataatgg agtacacaat aaagaaaatg tcagagatat caggagtcag tccgagaacc
     4561 ttgcgctttt atgatgagat tggactgcta aaaccagcta ggatcaattc ttcaggttat
     4621 cggatttatg gcaaaaaaga agtcgatcgt ctgcaacaca tcttatttta tcgaacaatg
     4681 gcattcaagt tggatgatat ccaagaggtc ttagacaatc catcttttga ccaccagaaa
     4741 gctttaatca agcatcagca aatgttgctg gaaaaacggg cacaaatcga taccctcttg
     4801 acaactgtcc aacagacact tgatatgtac gaaggaggaa gaaaaatgag tgacaaagaa
     4861 aaatttgaag ggtttaaaca acaaaagttg aaagaaaatg aagaatccta tggacaagag
     4921 attcgacaaa aatacggaaa aaaaaaggtt acagcatcca atgaaaaatg gatgaatatg
     4981 gataaagaaa cgtatgaaga aatgcaaact gttgaaaagc agatgttatt tgatctcact
     5041 ctttacttaa aagaaccaga agatgaaagc ttagcagacc gtatcttcca agctcataag
     5101 aagtggttct cttacagctg gcctgaatat cagccaaaag cgcataaagg actaggaatg
     5161 atgtacgaag ccgatgaacg gttcactgca tattatgacg agcgaagtgg tcatggtgca
     5221 gcaaaagctt taaatgaaat tatccaaaaa aaggcgtaat cttttacatg atccaacaaa
     5281 aaagtacacg taaaatgacc taataacaaa acagcagaca cccaagttag atttttatgc
     5341 taacttttgg tgtctgctcc attctttcac aagttttttc atcctacttt aaatatattc
     5401 atcgttgaat aaacgtataa ggtattttca ctttatcctt tttttctgta agaaacaatt
     5461 gaaatgccat ttctccgcaa gcttccagat ggtggtcgat ggttgggaaa ccaagaagct
     5521 cgctgatcag caaattatcc cgtccaatca ccactggtgt cttatcttgc agatagcttt
     5581 gcaagatgcc tgctgcaacc atatccgaat ttgtaaagac accatcaact ccaagctctt
     5641 taaaaaagaa gcctgcttgt tttcctttct ctgcatctat acaatcccaa aaaacaagtg
     5701 attcatcaaa agatggaaaa agttgatgac atagctgcaa agtgattttt gagttataac
     5761 ttagcctgcc acttcgcccc aacgtgatgc ccaattgctt tataccttgc tgcttcaaat
     5821 aagtaagacc ttctgtaatt gattgttctc gatcaataaa gacacagctt gcctgttttc
     5881 ccttgatttc ttcacaaaaa actagaggtc catatttttg atatgccaat aaatcatcta
     5941 gtgtattggc acgagacgta atgatcaatc catcgaaagc tttagctgca aattcttcaa
     6001 gataccttcg ctctttttct ttatgatagc ccgtcggtaa aagtgtcact ttgtaatcat
     6061 aatcaaacgc tgcttcaatg atcccactga tcaactgatc aaaatacgga tgattggtat
     6121 aaggcagaat cactccaatg cttttcgttt ttccataact taactgtctg gcatttgcat
     6181 tagggatata atcgacttct ttcatgaccg caagtatttc tttccttttt tcctcatcta
     6241 catatggatg tccattgatt acacgtgaaa tagtagaaac tgaataacct gtgagctttg
     6301 cgatatctcg aatgtttgcc actgctgctt cgccacctat acaaaaagat tttcttgtaa
     6361 atagtctacc acagctggac cgcattcaaa aaactgatac atttttcctt catgcgaaaa
     6421 actgatccgc tgcccgcccc aatatatatc ttttgtcaaa ttttcgattt cattcattgg
     6481 tatttctttt actatattcc tattcaaccc ttgaaaactg tacaacgtta atacggatcc
     6541 cttgaactcg acaaacgcat aaaaataatt gttcgttgtg ccatctgtta tctctacata
     6601 agtattcatt gcaagccctc cttttgatac tttgagtata gtgtatgaaa cgcgtctcat
     6661 agcaaggagt ttgttttgcc aaagaaaagt tttattcctc tttcattatt accaaagtct
     6721 cttattttaa attgaataca ttataatgat actgtaaata tatctttatt attagtgaat
//
LOCUS       DACCVZ010000120         6331 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.123, whole genome shotgun sequence.
ACCESSION   DACCVZ010000120 DACCVZ010000000
VERSION     DACCVZ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6331
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.123"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(99..1229)
                     /locus_tag="IVW63_002659"
     CDS             complement(99..1229)
                     /locus_tag="IVW63_002659"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAP7860889.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     gene            complement(1878..3080)
                     /locus_tag="IVW63_002660"
     CDS             complement(1878..3080)
                     /locus_tag="IVW63_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7860890.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="IVW63_002661"
     CDS             complement(3140..3343)
                     /locus_tag="IVW63_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP7860891.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="IVW63_002662"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="IVW63_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            4880..5692
                     /locus_tag="IVW63_002663"
     CDS             4880..5692
                     /locus_tag="IVW63_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7860892.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1886 a         1300 c          998 g         2147 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag a
//
LOCUS       DACCVZ010000121         6294 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.124, whole genome shotgun sequence.
ACCESSION   DACCVZ010000121 DACCVZ010000000
VERSION     DACCVZ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.124"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            21..1028
                     /locus_tag="IVW63_002664"
     CDS             21..1028
                     /locus_tag="IVW63_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP7860893.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            1040..2044
                     /gene="neuB"
                     /locus_tag="IVW63_002665"
     CDS             1040..2044
                     /gene="neuB"
                     /locus_tag="IVW63_002665"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HAP7860894.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            2041..3189
                     /gene="neuC"
                     /locus_tag="IVW63_002666"
     CDS             2041..3189
                     /gene="neuC"
                     /locus_tag="IVW63_002666"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HAP7860895.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            3162..3839
                     /locus_tag="IVW63_002667"
     CDS             3162..3839
                     /locus_tag="IVW63_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAP7860896.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            3829..4971
                     /locus_tag="IVW63_002668"
     CDS             3829..4971
                     /locus_tag="IVW63_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAP7860897.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            4984..5961
                     /locus_tag="IVW63_002669"
     CDS             4984..5961
                     /locus_tag="IVW63_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP7860898.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            5961..>6294
                     /locus_tag="IVW63_002670"
     CDS             5961..>6294
                     /locus_tag="IVW63_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAP7860899.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYV"
BASE COUNT         2349 a          792 c         1206 g         1947 t
ORIGIN      
        1 attcatagga ggagatataa gtgtttaaag gaaaaacaat attagtaact ggcggaactg
       61 gttccattgg aagtgaaatt gttcgtcagc ttttaaaata tgaaccaaaa gctatcagaa
      121 tttatagtag aggtgaagaa aaacaatttt atatgcaaca agagctctca aatcacacta
      181 atttgagatt tttaattggt gatatcagag actctcaaag gattgattat gcatgtcgtg
      241 atgtggatat tatttttcat gctgccgcaa tgaaacacgt tccagcaagt gaatataatc
      301 ctatggaagc tgtaaaaaca aatgtgatgg gaactcaaaa tgtaatagat gcagcgatca
      361 aaaataatgt aaaacatttt gtaggtatca gtacagataa agtagtgagt cctactaaca
      421 ccatgggtgc gacaaagtta ttgagtgaaa aattaataat agctgccaat cagtataaag
      481 gaaaaacaga aacaatattt tcttgtgtaa ggtttggaaa tgtcatgggg tcaagtggat
      541 ctgttattcc tctttttagt aaacaaataa aaaacaataa agatattact ttgacagatg
      601 ttgatatgac acgatttatg atgtcaatac cggatgctgc aagattagtt ctgtctgctg
      661 ctatgaattc aaaatttgga gaaacatatg tcttaaaaat gccggcaatc aatattttaa
      721 ctttagctca atcattaata aaaatatata atgatacaca tgatgaaaaa tatagaggtg
      781 aaataaaagt tgtaggtatc aggccaggag aaaaattata tgaagagcta atgactacag
      841 acgaaattga acgctcatat gaaaatgata aaatgtatat cattccacca cactatcatg
      901 ctactgacga actgtacaaa gattatgaaa aaattaaaat cactgcatac tcttcagatg
      961 caacagaatt aatgagtgga caggaattta ttagaatcgc aaaagagaat aatgtcgtga
     1021 cttggtaagg agttttatga tgaaatcaga agtatatgta attgcagaaa ttggtgtaaa
     1081 ccataatgga agtctagatt tagctttaga aagtattgat aaagctaaag aatgtggagc
     1141 taacgcggtt aaatttcaaa catttaaaac gaataagcta gtttccaaaa aggctccaat
     1201 ggcaaaatat cagaaggata atcttaaaga ggacagttct caatttgaaa tgctaaaaaa
     1261 attagaatta tctcaatctg attttattag aataaaagat tattgtatac aaaataaaat
     1321 tgattttttg tctactcctt ttgatgaaga aagtgcagac tttctaaaac aaattggtgt
     1381 acaaggattt aaaattggct caggagattt aacaaattta ccttttctta gaaaaataga
     1441 tatgtatggg ttgccagttt tattatctac aggtatggct gatattcatg aggtcagtga
     1501 ggctgtagat tgtttcatag atagtccagt tactatttta cattgtactt caaattatcc
     1561 ggctagttct gaagatatta atttattggc gattaacaca ttaaaagaaa tgttcgggat
     1621 acccgttggg tactccgatc attcattggg atatgatgtt ggtatttgtg ctgttgcgat
     1681 gggtgctaag gtaattgaga aacattttac cttggataag gaactacctg gtccagatca
     1741 taaagcttct ttagatcctc aggaatttgc agattttgta aagcatatta gaaacactga
     1801 aatattttta ggtgatggtg ttaagcgagc aatgccttct gaacttagta caaaagaagt
     1861 atcaagaaaa agcctagtgg tcactgagaa tttaaatgtg ggagatattc ttacagagaa
     1921 atctcttaca ataaaacgtc ctggaaatgg aatagctcct aagtttttat atcaatatat
     1981 tggcaaaaaa gttaaaagac caataagtgc agatagtgtt ctgcttgagg aagatgttga
     2041 atgaaaaaaa tacttatagt aagtggaaca cgagctgatt atggaatata taaacctgtt
     2101 gctgagaatt tactacaaga taattgggat gtatcatttg ttgtttctgg aatgcattta
     2161 tcccataaat atggatttac taaagaattg atcttagctg acggatttag aattagtgga
     2221 gaagttcaaa gtttgttttt agagaacaat aagggaaaca tggctcggtc tgtggcatta
     2281 gagataaatg gtttcacaaa tatatttgaa caaactagcc ctgattttgt attattacta
     2341 ggggatagag gagaaatgtt ggcagctgcg atagcttgtt tgtatcttgg aatcaaaaca
     2401 gcacatattc acggaggcga agtgtctggt actgtagatg aatcaataag acatgccata
     2461 acgaaaatag catctgttca ttttgctgct acggaaaaaa gcaaagagcg tttaataaaa
     2521 atgggggaag attcttggag agtttttccc gtcggagctc ctagaataga tactatttta
     2581 aataatagat tacctagttt tagagatata aaagaaaaat atcatctaaa atttgaaaag
     2641 aaaaaatacg ttttgcaagt atttcatcca gttgtaaccg aactagaaaa tatagaaaaa
     2701 caaattttag ctttgatcaa ttcaatggaa caacaatctc aaccaattat ttgcatttta
     2761 cctaatagtg atgctggtag cgaaattatc agaaaaatgt accagaaata tttaaaaacg
     2821 gatattattt atattacgaa tttagagccg gaggaatacc tgactatatt aaaagagtgc
     2881 aaatttatga tcggaaattc ttcttctggg ataattgaag ctgcatcatt caaaatacca
     2941 gtaataaatt taggaaccag acaaaatgga cgagaacaat ctaaaaatat tataaatgca
     3001 aatctaaatg aaaatgaaat tgaaactgct ttgaataaaa tacaagatcc tcagtttata
     3061 aaaagcttga aaaatgttaa gaacatctac ggtgacggca acagttctag aagaataaca
     3121 aaaacattga atcaaatatt gaatgatggg gaagatatta agtggattca aaaacaaata
     3181 gcttattaaa atatactagt gatccataca ttattattgg ggctggcgga cacgcaaaag
     3241 tcattattga aaccttaaga ttagaaaata agttaatata tggatttttt gatgataagc
     3301 aaaataaaat gcaagatctg aaatatcttg ggaaaataaa cgaattgaat agctgggcgg
     3361 atagcaaaaa aaaaatctat aaatttattg tagctattgg tgactgtgta gtaagaaaaa
     3421 agattataaa aaaattgaat atgccaagtg agcaatatgg aatagctgtt catccaagtg
     3481 ctatagtggc aaaagaaatt tcaattggtt atggaactgt tatttttgcg aatgctgtaa
     3541 ttaacccaga tgctgtaatt ggagagcatg ctataataaa cacaggtagc attgttgagc
     3601 atgattgtag aattaataac tatgttcatt tatctccagg tgtatgctta gcgggtggag
     3661 tacatgtagg tgtaggaact caaataggaa ttggttctca atgtatccag atgaagaaaa
     3721 ttggatcttg gtgtatgata ggcgcaggga gcactattgt taaggatatt ccctcacatt
     3781 ccttagctta tggcaatcca gctaaaatta agaaagaagg aattaatttt gaattctaga
     3841 attttattat caagtcctca tatgggagga acagaagaaa aatatgttgc taaggctttt
     3901 aaagataatt ggatagcgcc attaggtgaa aatgtggata aatttgaaga aagtattaca
     3961 aaatatactg gttctaaggg cggagcttct gcgttaagtt caggtacagc tgccatacat
     4021 cttgccttaa gactgcttaa tgttggaaaa aacgatattg tctttgctcc ttcatttact
     4081 tttatagcta cagtaaatcc tattttatat caaggggctg taccagtgtt cattgactca
     4141 gaacctaata catggaatat gagccctgtt gcactagaga gcgcattaga agaagctgaa
     4201 agaaacaacc aattacctaa ggcaatcatc gtagtgaatt tatatggtca aatggctgat
     4261 tatgaacgaa ttttagctat tgcaaaccaa tttaatgttc cagtgataga agatgcagcg
     4321 gaatcgttag gttctactta taagggaatt tcgtcaggct tatttgggac aattgggatc
     4381 tattcattta acggtaataa gatcatcaca acctcaggtg gaggagctct agtgtctagt
     4441 gataaaaaat atgttgagca ttcaagattt ttagcaacac aagcaagaga tcaagcaccg
     4501 tattatcaac atagcgaaat aggttataat taccgtctaa gcaatatttc tgccggtatc
     4561 ggacgtggac aaatggaagt attgaatgat agagtagcta aacgaagaga aattttcaat
     4621 cgatataagg aagctttttc tggaattgat agaattgaaa tgatgccaga agtggatggc
     4681 atggtgccaa atcgttggtt gtctacttta acgatcaatg attataattc tattgatcaa
     4741 gtagttaacg taataaataa actaaatgaa aaaaacattg aaacaagagc tttgtggaaa
     4801 ccactacatt tgcaaccagt atttcaaggg gtaaaaatgt attaccatga taataatctt
     4861 agtgtgtcag aaaagttatt taatagcggc ttatgcttac cttctggaag taatatgaca
     4921 gatagtgaac aagaatttgt tattgatgag tttaaaaaaa tattcaagta ggtgtgatat
     4981 tttatgaaca taggaattat tggtttaggt tccatgggga aaagaagact tagactcatt
     5041 caagaacact ttaatgatat tttactatgt ggtgttgata ctaatgaggc gagacgaaag
     5101 gaagttgaaa aggaatttgg aataccaact tataatagtc taacagaggc aaaaaatttg
     5161 tttgaaataa attcagtttt tgtttgtaca tcccctataa cccatgaatt tattataaaa
     5221 gaggctttaa atttagattg taatatcttt acggaaatca atttattaaa tgaatattat
     5281 gatgaaataa tcgaagtagc taaaaagaaa gatagattac tttatctatc ttctacattt
     5341 ttgaagagaa aagaaattca atatattaag tctaaagtga cgcataataa aaaaatttct
     5401 tatcaatacc atgtaggaca gtatttaccc gactggcatc cttgggaaga ttatcgcaat
     5461 ttttttgttt caaacaaaaa aactaatggg tgtagagaaa tattcgctat tgaattacct
     5521 tggattatag atacatttgg gaaagttaaa tcgtttactg taatgaccca gaaattatcc
     5581 aatcttgata ttgattattc ggacagtttc actcttatta ttgagcatga aactggtata
     5641 gttggaactt taagtgtaga tgttgtttca agagtagcta aaagaaattt aactataatt
     5701 ggtgaaaaga ttttaataga atgggaaggt aacccggatt ctctattttc atggaatgaa
     5761 gaaacttcta gtatgacaga tattcaattg tacgatgagg ttatgcatga taataattat
     5821 tcacatacta ttattgaaga tgcatattta gaggagatta aagaattttt cacgcttttg
     5881 gaaaagaaaa tggaacccca atatactttt gaaaaagata agtatattat taacttaatt
     5941 aacgacattg aggtaaatta atgatgaaag taattttttt tgggttaggg tcaattggaa
     6001 agagacatct aaaaaatcta ataagctatg gaaaaaagaa ttctattaat tttgatataa
     6061 cagcttatag tagcagtgga aaaaaagagt ttgaagaaat aacgtatatt caaaatagag
     6121 acgatttgga tacacattat gatatagctt ttattacaaa tccgactttt aagcatctgg
     6181 aaacactaaa tgtaattgtt gaaaaagttg attacatatt tttagaaaaa cctgcttttt
     6241 ctgagagtat tgatcttact caatataatt atgattacaa aaatatttat gttg
//
LOCUS       DACCVZ010000122         6242 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.125, whole genome shotgun sequence.
ACCESSION   DACCVZ010000122 DACCVZ010000000
VERSION     DACCVZ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.125"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            352..1041
                     /locus_tag="IVW63_002671"
     CDS             352..1041
                     /locus_tag="IVW63_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7860900.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1028..2236
                     /locus_tag="IVW63_002672"
     CDS             1028..2236
                     /locus_tag="IVW63_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7860901.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2530..3801
                     /gene="serS"
                     /locus_tag="IVW63_002673"
     CDS             2530..3801
                     /gene="serS"
                     /locus_tag="IVW63_002673"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAP7860902.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="IVW63_002674"
     CDS             complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="IVW63_002674"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAP7860903.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
BASE COUNT         1917 a         1172 c         1215 g         1938 t
ORIGIN      
        1 tttccaacat gtcaacaact tattttttat tatttaataa gttattggtg ttcttttgaa
       61 caaataataa tatatcaaca tcacatgtga aagtcaataa gaaaatgctt atttatcaac
      121 atttctagct tacatgatca ttggttagtt ctggtccttt ttcgttcgtc tttataactc
      181 cgagagacgt aaaatccttt tgttttcagt ttaatgttca tgttcttgtc ttattcacac
      241 caactagatg tctcaccttc taaaattttc cttaacaaag tgctgctttt atctatttct
      301 gctttttttt gctagaataa tagtaacaat atgactctgg aggatttatt tatgaaaatt
      361 ttgattgctg acgatgataa agaaatcgtt gaattattaa gtatctatgt tcacaatgag
      421 gggtatgaag cagtaaaggc ttatgatggg aaagaagcat tatctaaaat cagaacaatc
      481 cctgatattg aattacttat tttagatatc atgatgcctg agatggatgg gatgcaagta
      541 gtgaaagagc tacgaaaaga atcccaaata ccaatcatta tgctgacagc aaaaactact
      601 gatatggata agatcaaagg actggtcgct ggtgcagatg attatgtgac caagccattt
      661 aatccgttag aagtaatggc tagagtaaag tctttattac ggcgtacaaa aatgcagatt
      721 gccccagatc agcctgatgt attagaagta aatgcattaa tcatcaataa agactctcat
      781 gaagttaaaa caatcgatgg gaaagaaatc cagttaacag ctttggaatt cggtatcctc
      841 tacttgcttg ctagtcatcc taatcgagta tttagcgcgg atgaaatttt tgagcgtgtt
      901 tggaaacaag aaagtattgt ctctgctaaa actgtcatgg ttcacgttag tcatttaaga
      961 gataagattg aagaagcaac tggtggtgaa aaagtcattc aaaccgtttg gggagtgggc
     1021 tataaaattg acgcaagata gtaaacgagc aactgaaaaa cgccgtcgga tcaatttgac
     1081 ttcaaaagaa atcagcgaat tgttagcgga aggaatcatc acgattatcc ttttgcttct
     1141 attaaatgtt tctattctgg ttgttatcag ttcggtgatc aacagttcac cttctttgac
     1201 gaatgcgatt tgggattcaa agaatatttt tgcagaacga ttgaacactg atttgttctg
     1261 gaacggccgg aattttatta ttcccttttt ctttctatta gatattggtg ttttgtattg
     1321 gcgcttgatt cgaagatatc gccaaatgca attgcggcat atcatcagcg aacttcacta
     1381 catcgcaaac ggaaattatg atcatcgtat cccttttgaa ctgagtggtg acttaagccg
     1441 agtggtaaca agtatcaatg gattggtgga tagtaccgta gcagcgattg aagacgaacg
     1501 taaaatcgaa aaatcaaaag atgaattgat cacgaatgtc agtcatgata tccgtacccc
     1561 actcacgtcc atcattggat acctaggact gatagaagat ggccagtatc actcagaaga
     1621 agatctttta aagtatacgc atactgctta tatcaaagca aagcagatga aatctttagt
     1681 ggacgactta tttgaataca ctaaggtacg ccagcctgct gtcccggtga atttttctgc
     1741 ctttgacatg atccagttga tcgaacagtt agcagctgat tttgagttgg aagcttctaa
     1801 aaaaaatatc caaatacttg ttcaatcaaa agtagactcc cttatcatgg atggcgatac
     1861 cgaaaaactt gtacgtgtct tcaataatct tttgacgaat gcgttgaaat acggaaaagg
     1921 agcaacgaag atcgtaatcg aagtagaacg tatcggttca gaagttgttg caacagtcaa
     1981 aaataacgga gcaatgatcc cacaacaggc aatcgataat ctattcgacc gtttttatcg
     2041 tgtagaagaa tctcgttcac aagcaactgg aggaactgga cttggtttag caatcgctca
     2101 aagcattgtg gctttgcacg gcggatacat ttatgcaaaa tcagataagc aatggacttc
     2161 tttcatcatg caccttccaa tcaagaaaaa tgaaaaatta cctattgata cacaggaagt
     2221 tattgacgaa agctgaaata ttcgctattc ttattacaat tattagaata aatgaaaaac
     2281 acagaaccca gtacacttta ttctttttca gagagctgat ggcaggtgta aatcagcaaa
     2341 ggataatttg gaagttccag ttcgtttacg tgccctttcg aaataagaaa ggtcggttca
     2401 acagccgtta tgtgttcaac aagtgcagct gacgctgaac ttgggtggta ccgcgaattt
     2461 cagactgatt cgtcccaaga ataatgggat ggatcagtct ttttttattt tcaaaaagga
     2521 ggaaatcata tgttagatgt aaaaatgatg cgacaaaata ttgaagaagt acaagaaaaa
     2581 ttgatgactc ggggcgtaaa aaaagaaaca ttagctgaat tcatggaact agatgaaaat
     2641 cgtcgtaagc tactagtcaa aagtgaagaa ttaaaaaaat atcgaaatga tgtttctgct
     2701 gagatcgccc aattgaagcg tgcaaaagaa gatgcttctg ctaaaatcgc tgaaatgaaa
     2761 gaagtcggtg gcaacatcaa agcattggat actgaaattg ctgaagtgga tgaaaaattg
     2821 aaacaaattg caactacttt gccaaacctt ccccatgatt ctgtgccagt tggaacagat
     2881 gaagaggaca atgtagaaat ccgtcgttgg agcgaaccac gtacatttgc ttttgaacca
     2941 aaaccacact gggaaattgc agaaaatctt gatattttag attttgaacg tggcgcaaaa
     3001 gtagccggta gccgttttgt ctattacaaa ggattaggtg ctcgattaga acgtgctgtc
     3061 tacaacttca tgcttgatca gcatatttac gaacacggct atactgaaat gatcactcct
     3121 tatatcgtca acagtaaagc gatgtttggt acgggacaat ttccaaaatt caaagaagat
     3181 gttttccaat tggagaatac tgatctaaca ttaatcccaa cagctgaagt accattaact
     3241 aactattata atgatgaaat tttagatggt gcagatttac ctatttattt cactgcacta
     3301 agccctgctt ttcgttctga agccggaagt gctggtcggg atacacgagg actgattcgt
     3361 cttcaccaat tcaataaagt agaaatggtc aaattttcgg atgtagagca ttcttacgaa
     3421 gaattggaaa aaatgacagc tgatgcagaa gatatcttga aaaaattgca tttgccttat
     3481 cgtgtgatgg ccttatcaac tggagacatg ggcttttctg cagctaaaac ttatgactta
     3541 gaagtatgga tacctgcaca agatacttat cgtgaaatca gttcttgttc taactgtgaa
     3601 gatttccaag cacgccgcgc aatgatccgt tatcgcgata atgatggaaa aatccactat
     3661 actcatactc tgaatggttc aggacttgca gttggccgta cagtagctgc cattttggaa
     3721 aactaccaaa atgaagatgg ttctgtcaca gttccagaag cgctcgttcc ttatatgggg
     3781 aatctgaaag ttattaaata aagaggctgt gaaaaagccg cttagtttcg agtattaaga
     3841 aaaattttgt gaaaatggct ttccacattt ttgcataaat tggacttaat accgagaaac
     3901 tggcttttga acaccattta tcgagaggtt gtgaaatcag cgaattaacc tgagtattag
     3961 agaaaaaaat ggaaaaatag tccctcatat tttaccgttt gttgaactaa taccgagggt
     4021 cagctgattg aacaccgttt agtggagagg tcgtaagcct accccccagc tcctagttac
     4081 aaggacaaat tcaaaaaaca gctcttcata ttttatgaat gttgtacttg tgattcggag
     4141 gtggcaaggg aacactgttt attcaaaaag aggctgggac agaagcgttt aactccaaga
     4201 aataagaaga aattcacgaa aattgctttt caaatttttg tgaatttctt cttatttccg
     4261 aaggagttgc ttctacttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct
     4321 ttacttttgt cccacgctct ttaatgtttt taagattcaa ctgaatagtt tggtgcttct
     4381 tttgtgattt gtacatcatg agggtgtgat tcttttaatc cactgccgct catttggata
     4441 aattgcgctt catcacgtaa ttgctgtaga ttggctgccc caacataacc cattcctgaa
     4501 cgcaaaccgc cgatcatttg gaaaataata tctgcaacac ttcctttata agcaacccga
     4561 ccttcgattc cttctggtac taatttattt gcttcattga cactaccttg gaagtaacgg
     4621 tcttttgaac ctttttccat cgcgcctaat gagcccatac ctcggtatgt tttgaatcga
     4681 cgtccttgga agatttcgaa ttcacctggt gattcatctg tccctgccaa catacttcct
     4741 agcatcactg catgtccgcc ggcagctaat gctttgacga tgtcaccaga atatttgatc
     4801 cctccgtctg caataatcgc tttgccatat tgacgagcaa ctgatgctgc atcataaata
     4861 gctgtgagct gaggtacacc tacaccggct accacacgtg tcgtacaaat cgatcctggt
     4921 ccgataccaa cttttacgac atctacacct gcatcatata aagcttttgt cgcttcagcc
     4981 gtcgcaacgt ttcctgcaat caatgttgca tctgcaaaag ttgaacggat ttcttgaatt
     5041 tttcggatca cacctgcact atgtccatga gctgtatcga tgatgattgc atctgcccct
     5101 gcttctaata aagcattcgc acgctcaaat gtatcgcttg ttacaccaac ggctgctgct
     5161 acaagcaatc gaccatgttc atcttttgct gcatttggaa attcgatcac tttctcgatg
     5221 tctttgatcg tgatcaatcc gcttaaacga ccttcgttat ctacgattgg taatttttcg
     5281 attttatgtt tttgcaaaat cttttctgca tcttttagag aggtacctac tggggcagtc
     5341 actaagttgt cttttgtcat cacatcagca atcggcatgt gataatctgt tacaaaacgc
     5401 atgtcgcggt ttgtaattat ccctaccaat tttctgtttt caagtgtttc aacgattggc
     5461 acaccactga tacgatattt gctcatcaat tcttctgcgt ctgctacaag atgctgcggc
     5521 gttaagaaga acggatcaat gattacgcca ctttcagaac gtttgacttt tcttacttca
     5581 tccgcttgct ggctgatcgt catgttttta tggatcacac ctagtccgcc ttgtcttgcc
     5641 atagcaatgg ccatcttgct gtcggtaaca gtatccatac ttgcactgat gattggaata
     5701 ttcaacttaa tatttttagc taattgtacg ctcatatcca cttcgtttgg taacacgtga
     5761 ctttctgctg gtatcaataa gacatcatca aaagtaaatc cttttttcgt gaactttgtt
     5821 tcccagttgg acatttttag taccactcct ctaatttagt ttatctatta aaataattga
     5881 ttttttcatt taagtcaatg atctacttgg aatcaagtta gctttctcat agaataccaa
     5941 tataaagcgt ttacatctgt gtgtattaaa agagattgta aaaaagctgt cctgcatcaa
     6001 gtaataagaa cagccaatca aaaacagctt ctcatgtttt tgaattggtt gggtttatta
     6061 ccgcagatgc aaacttttga acaccgttta gtggagaggc tgtgaaaaag ctgcttagtt
     6121 tcgagtagta agaaaaattt tgtgaaaatg gctttccaca tttttgcata aattggactt
     6181 aataccgaga aactggcttt tgaacaccgt ttatcgtaaa aagggactgt gacaagactt
     6241 tt
//
LOCUS       DACCVZ010000123         6230 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.126, whole genome shotgun sequence.
ACCESSION   DACCVZ010000123 DACCVZ010000000
VERSION     DACCVZ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.126"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            133..633
                     /locus_tag="IVW63_002675"
     CDS             133..633
                     /locus_tag="IVW63_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAP7860904.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            730..2577
                     /locus_tag="IVW63_002676"
     CDS             730..2577
                     /locus_tag="IVW63_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HAP7860905.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2580..3476
                     /locus_tag="IVW63_002677"
     CDS             2580..3476
                     /locus_tag="IVW63_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7860906.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3526..3915
                     /locus_tag="IVW63_002678"
     CDS             3526..3915
                     /locus_tag="IVW63_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP7860907.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3902..>6230
                     /locus_tag="IVW63_002679"
     CDS             3902..>6230
                     /locus_tag="IVW63_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP7860908.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2106 a          925 c         1336 g         1863 t
ORIGIN      
        1 gagttttcca aactgattgg cttcttggtg attgctttga ttgcggtagg tctggtcttt
       61 aatgcttctg gtgtgaagga tgtcttactc aatttgttta accgaattgt cggtgcctga
      121 gggggaatca caatggaaca gatacgtgtt tatattgcga accttggaaa atacaatgaa
      181 ggtgagttgg tgggggcatg gtttacccca cccgtcgatt ttgatgaagt gaaagaacgg
      241 attggattaa atgacgaata tgaagagtac gcaattcatg attatgaact gccttttgag
      301 attgatgagt atacaccaat tgaggaaatt aatcggttgt gtggtttagc ggaagagctt
      361 aaaggaacgc caattggtga ggtcgcttca gagattcaac atgccttctt caattctttc
      421 gaggaaatgg tagagcatgt ggatgatatc atctattatc ccgattgtaa tgacatgagt
      481 gatgtagcgt attacttgat tgtagaagct ggtgatttag gcgaagtacc agaacacttg
      541 aagacgtata ttgattttga tgcgtgtggt cgagacttgg agattggcgg gaattatttg
      601 gttacgagtc gaggggtttt tgaactaatg taaatcattt gttagaattg accagaaatt
      661 tctatcgtac ttttactttt ctatttgata tactgaaata gaaaatattt gttgataggg
      721 gtgttactaa tggttggcaa taagtggtac aaatgtgatc ttcatattca ttcaactgcg
      781 agtcagtgct ttcaggataa aaaggttact gctaaggaat gggtagaaga atgtttaaac
      841 aaaggactcg attgtgttgc attaactgat cacaatacag gggaaaatat tgatgaatat
      901 aagaaagtgg ctatcgaaaa tggcttagat ttttttcctg gagtggaatt aacgtgtgga
      961 gaaaatggaa ctcatttact agtcctattt gataaaagtg catgtacaaa tgatatctct
     1021 gatttcttaa ccaagatggg tataaaaaga gaggattggg ccagcgctgc agcttgctca
     1081 atgaaatcag ttttagaagt tattgatttt gctgagcacg agggcttgct cgttattcct
     1141 gcacatatag atgagtttaa tggaatttct tcagcaaaat ttggaaatct aggaaagata
     1201 tttgaatcag aaaatatata tgcagtacag acggttcaaa aagaattttt tgaaaatcgc
     1261 tcacaaatga ttccctcatc taagcgtgac actatctatg atagtgtgaa tgccagatat
     1321 gatggtagag ttggaaaaga tactttggaa tcttggtata aatcagttgt tgaggcagaa
     1381 aaaaataata tgacatttct tagcttttct gataacccac actcgaaagg aaattcaaaa
     1441 catggacttt ggggaatagg cacaagatat tcctatataa aaatgaagga cgaacctgac
     1501 ttgggatcac ttcgcgatgc tttaatgcta ggcgaaactc gagttcattc tgatttttct
     1561 aatttctcca ttaatgaaaa tgaagtttta ttggaaaaat taagcttttc tgggaccact
     1621 cttagcacaa aagaagttgt agtcgaattc agcgataatt taacttcaat tattggagga
     1681 agaggaacag gcaaatcttg tattacaaga ttcttggtct atgtccttgg aaaggaagca
     1741 gaacttgatc aattttctga aatacaaagt gattatcaga actttgcaca aattgaacat
     1801 aatggctctg gaatattttt gaaggataca attgtgaaac tgaatatttt ctataagggg
     1861 acaaaatatc aaataataag aacacaggat agacattcta tttatgaatt tacacaagag
     1921 aatggtctgg ttgaaaaaga aacagaacgg ttgagaatga tttccgataa ggtgagtata
     1981 tactctcaaa aacaaattta tgaaatttca aaaaatcaaa ctagtatact agaattacta
     2041 gatggatata actctgattt gatttcagag tataaaaatg agattgaaac atgtgtaaac
     2101 gaaataagaa aattaaattg ggatattgtt tctgtgaaaa aagaaataca agataaggcg
     2161 aaggtagagc ttgaaattga agatttaaaa aaacaagtag aaaagctatc tcataagagt
     2221 tataaagatg tttatgatga gtattcaaaa gagacagata tttataggga actgaaacgt
     2281 gatgtggagg cacttaagga aattcccaaa aatctaactg atagtgttga caaaattgac
     2341 tttggcaatg gtataaaagt tacagacgaa attgatgaac accgcggaga attgattaag
     2401 aatttagtga ccaatcgggc taagattcaa acaataatta atgaaatgtc agatgaaatt
     2461 gatagttata gagcagagct gaataaatca gattggaaag ttaactataa tgaggtttca
     2521 aagaggtatc aaagaggtat caaaaactta gtgaagagtt atctcaagat gaattaaaaa
     2581 tgttacaaaa ccttgattct ttatatcaat ctttatcaaa aactgaagag cgattggaag
     2641 aaattattca acaagaaata aagcttaaag attaccaagt tgaggttgac tcagcaatgt
     2701 caagaatgaa taaatcatat caaaatctct attctgagag aagtagttcc tcgcgcgaaa
     2761 ttttttctga tattacagga atagaggcta ctattcaacc aaatagggat ttcaataatt
     2821 atgttaaaga gctcagagct tgtattaata aggaggacac ttttgacagt gagtttggat
     2881 ctcttattga taagctgaca aaaaattcca ttactaatca agatatatat aatgacatac
     2941 ttgatataag agttagtggg gaaagtagta ttttttcaga taaaaaatta atcaattcta
     3001 taagaaaatt gaatgatgca caagttcttg aattacaaac ccttaagcca aatgatttag
     3061 tagttatccg acttgaacta aatggaaaaa aagttagttt atcgaatgct agtgctggtc
     3121 aaaagacatc tgcaattctt tctatgattt tggcgtatgg aaattcacca ctcatattgg
     3181 atcagcctga agatgatttg gatagtcaat taattaataa cttaatcgta agaagtatca
     3241 ttacaaaaaa ggaaaacaga caaattttaa ttgtaactca taatgcaaat atcccagtta
     3301 atggtgattc agaatggttg attagcatgg gagattcaaa agaaatatcg gctgatcagt
     3361 gcgggtcggt agatgaaccc aatatcaagc caagaatatg tactgtgatg gaaggtggcg
     3421 aggatgcttt tacaaataga gcgaaacgct atggttttaa acaaattgta gaataacact
     3481 agagggtgag acatattatt atgtccgccc tttttaggag gaaaaatgaa aaaaataaaa
     3541 agctatacca gtatctgggc agttgaaaaa gtcatttacg caatcaatga ttttcagttg
     3601 ccttttcctg tgacttttaa ccaaatggct tggttcgttt tatctttact gtttgtcatc
     3661 gtatttgccc atgtgcctcc actatctatg atagaggagg tctttttaaa atacttaggc
     3721 ataccggtgg ctgtcacttg gtttatgtcg caaaagacgt ttgatggcaa gaaaccactg
     3781 ggatttttac gatcctttat cagctatcac ttgcgattta aggtgacttt tgcaggaaag
     3841 aaagtcaaag aacagaagaa acgatgggat gaacccagta ctcttgtaag gagtgtgaac
     3901 tatgtatccg attaagtata ttgaaaataa tctcgtcttt aaccaagaag gcgagtgttt
     3961 tgcctactat gaattagtgc cttacaatta ctcctttttg tcacccgaac agaaatttca
     4021 agtgcatgat aactttcgcc aactaattgc gcaaaatcgt gaaggcaaga tccatgcgtt
     4081 acaaattgcc acagaaagta gtattcgcgc cacacaagaa cgatcaaaaa aagaaattac
     4141 cggtagactc aaagaagtag cgaaacaacg aattgatata cagacagatg cattagtatc
     4201 catgattggc gatagtcaga ttgattatcg cttttttatt ggctttaaac taattgcgac
     4261 agatgaagaa gtcaatctaa agagtctcaa gaaatctttc ttttctgggc ttcaagaatt
     4321 tgtctatgga gtgaatcatc atttgatggg cgattttgtt tccttatcca atgaagaaat
     4381 tcgctgctat tctaagcttg aaaaattaat ggaaagcaaa ttggctcgaa gatttaaagt
     4441 caggcgagtc acaccgagtg acctgacgta tttgattgaa catatttatg gcgaaaaagg
     4501 gataccgttt gaagaatacg aatttcagct accaaagaaa aagctaaaat cagaaacact
     4561 ggtgaaacgt tatgacttat tacgtccaaa tcgttgttta attgaagaaa aaccaaggtg
     4621 cttacggatg gaacatgaga atcatgagtc gtacgtagcg tatttaacaa ttaatacaat
     4681 tgtgggggag atggaatttc cttcctcaga acttttctat taccagcaac aacaatttac
     4741 attcccaatc gacacaagta tgaatgtaga gattgtgacg aataaaaagg ctttagctac
     4801 cgttcgtaat aagaaaaaag aactgaaaga tttagacaat catgcttacc aatctgacaa
     4861 tgaaacgaat tccaatgtct tagatgcttt ggattccgtg gatgaattgg aaaccacctt
     4921 ggatcagtca aaagaatcta tgtacaaact gagttatgtg gttcgagtga gtgccgaatc
     4981 agtggatgaa ctaaagcgac gctgtgatga agtgctcgat ttttatgatg ataccaatgt
     5041 aaaactagtc cggccctttg gcgatatgat ggggctacat gaagaattct taccctcaag
     5101 taaacgatat atgaacgact atattcagta tgttacgtct gattttttgg cggggcttgg
     5161 ttttggggct actcagatgc taggagaatt agaagggatt tactttggct acaatgtgga
     5221 tacaggtcgt aatgtttacc tgaaaccggc attggcttca caaggagtca agggttcagt
     5281 aaccaatgcg ctggccgccg ctttcctggg ttctcttggt ggaggtaaat cctttagtaa
     5341 caatctctta gtctactatg ctgttttgtt cggtggtcaa gctgtgattg tcgatccaaa
     5401 aggggagcga ggagggtgga aagaaacctt gccagaaatt gcggatgaaa tcagtatcct
     5461 caacttgacg agtaagtcag aaaatcaagg tctgcttgat ccttatgtga ttatgaagaa
     5521 aaagaaagac tcggaaagtt tagcaattga tattctgact tttttaacag gaatttcaag
     5581 tcgagacggg gagaagtttc ctgtgttacg taaagccatt cgaacggtga ctcaaagtga
     5641 tcaacggggg ttattacaag ttattaacga attgcgaaaa gacgggtcac caatcgcgga
     5701 aaatatcgcc gatcatatcg agtcctttac cgattatgat tttgctcatt tgcttttctc
     5761 agacggctcg attacccaat cgattagttt agataaacag ctaaatatca ttcaagtggc
     5821 ggatttggtt ttaccggatg cagaaacgac ttttgaagaa tataccacca tggaattgct
     5881 tagtgtttcg atgctaatcg tcatttccac ttttgccttg gactttatcc atagtaaccg
     5941 agaaatcttc aaaattgtcg atttggatga ggcttggagt tttcttcaag tggctcaagg
     6001 aaaaacgtta tcgaataagc ttgttcgtgc tggtcgggcc atgaatgctg gggtctattt
     6061 cgtcactcaa aatagcgacg atttattaga tgaacgttta aaaaataata tcgggttgaa
     6121 gtttgctttt cgcagtaccg atattcatga aatcaagaaa accttggaat tctttggttt
     6181 ggatcaggag gatcaaagca atcaaaaacg cctgcgagat ttggaaaacg
//
LOCUS       DACCVZ010000124         6174 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.127, whole genome shotgun sequence.
ACCESSION   DACCVZ010000124 DACCVZ010000000
VERSION     DACCVZ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.127"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            725..811
                     /locus_tag="IVW63_002680"
     CDS             725..811
                     /locus_tag="IVW63_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAP7860909.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="IVW63_002681"
     CDS             complement(932..1621)
                     /locus_tag="IVW63_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860910.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="IVW63_002682"
     CDS             complement(1628..1906)
                     /locus_tag="IVW63_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860911.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="IVW63_002683"
     CDS             complement(1866..2780)
                     /locus_tag="IVW63_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP7860912.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="IVW63_002684"
     CDS             complement(2762..3142)
                     /locus_tag="IVW63_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAP7860913.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3593..3880)
                     /locus_tag="IVW63_002685"
     CDS             complement(3593..3880)
                     /locus_tag="IVW63_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP7860914.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3900..4124)
                     /locus_tag="IVW63_002686"
     CDS             complement(3900..4124)
                     /locus_tag="IVW63_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HAP7860915.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4764..5297)
                     /locus_tag="IVW63_002687"
     CDS             complement(4764..5297)
                     /locus_tag="IVW63_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAP7860916.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5318..6160)
                     /locus_tag="IVW63_002688"
     CDS             complement(5318..6160)
                     /locus_tag="IVW63_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAP7860917.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1635 a         1152 c         1040 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccaac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag cttactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgccaaaggg gcgcaagctc ccccttgaat ccccctcccc ccccactctc cacaatacaa
     3361 aaaagactag caaatgctag ccactttttg taaagtttcg cttgtttcac cttcggtgaa
     3421 attgttgcaa atcaataatt aggtagagct acattttttt cgttgttcaa agattcttat
     3481 gccatttact attaataaat ctataaatat gataattttt cggctctata atttatggga
     3541 ctgatgaatc agaattgatt cttcagtccc attttcattt tattccaaag aattaactcc
     3601 aaataccaat agaagcccat cctctatata cttgagattc cttactaaca atttcttgta
     3661 attctattaa agatttaggt aatccaaatt tatgttttaa aatatatctt ccaagaaaac
     3721 tacttaattt catactaact tcaccaacac tttttccctc actgatttct ttagaataaa
     3781 gaaagagctt ttcttttaag tcaggatagt catctatagt tgcttcattg tatactttac
     3841 taattgcatt taaaagtttt tcttctttag taaaatccat tataataacc tccctaccac
     3901 taccttctag gtgcccatgg accatgatta acccaaccat taacaataat ttttccaatt
     3961 tctcctttag cttgattcca atctacccaa catttttctt tgttacaata aagaccattt
     4021 ccatagtaag tagctgcatc aacttttatt cctgtaccga tgccagctag acaagttcct
     4081 aatattccta gaataacaca atgttttaat actttctttt tcatgattgt ttttcctttt
     4141 cgttttttta aaattgcttg ttatattaaa taatcttagt aattttatta tataacattt
     4201 tattatataa caatgattaa cgtcataaaa agtagttttg aattcataat cgtttaaata
     4261 aaattataag atcagttatt taaacagcta gtagacataa tgtatatact accaagtaac
     4321 gcctgtacca agggatccag gcgctgattt tgtgaatttt tattggtcta ggttaaaagc
     4381 tctttttaag gcttggtttt ctgcggttgt ttctttctaa ttctttgtga atattgatcg
     4441 gtcatttttt aaatacttgt tatttttgtt tgtgtttgtt atgcttttta catatctcat
     4501 attcatttat tattcttttc taaggttaat aataggataa tctctttcag aaagactgct
     4561 cgtacgagca gtcttttctt atttatcaag tttttctaca aatacttcct cattttgact
     4621 gttgtagtaa ttaggattga gttttagttc ccctttttta tttcctttgt tggccactga
     4681 taataacatt gggctaaagc ttaatattcc tagtaggata gaaccgaata gcaagtgttt
     4741 ttttgtcata agtatttcct tcttcatttc catagctgcc accatttttt ccaattcttt
     4801 gtttgttcgt ccattgtttc tgttgcttca gaaagagtcg ttgaactatt ctctgaagac
     4861 tcttccgtat aagtcaactg cagttgctcc tgaagttttt cgatttgttg gttggcttgc
     4921 agggtgagtt gttgttgctg gtcgagtagt ttttgtatat gagaattatt ttgctctttg
     4981 agggcaagtt gttctcgtaa aaattcattt tcttcacgca actgatctag caacttgttt
     5041 gcaaccacgt ttttgtttgg tatataagca tttttatcgt tgttttgttc atgtttatgc
     5101 aacttatcta gcaacctttg attgtctaag ttgcgagcaa gttgcaatac tccagaacgc
     5161 aatacaacct tataaccacg ctcattttta gctatcatgg aagaatctaa tttttggata
     5221 tgtttcgata ttgcttgcct actcatctta aaaagatctg acaattcctt tattgtaaag
     5281 gtttcttgtg gttgcatact ggttgcctcc taggttgcta ctggaataaa ttatctaaat
     5341 cagataataa actttttttc tctttttccg aaagtgcgga ctctgtttgt ttttcaagag
     5401 cttttttctc tttttctagt tgtttgattt gttggaggag ttcaagttct cgtttcttct
     5461 gtttgatttt ttcgttaatt gttgtagcgg gttcttcgta ttctttttgt ttatcagcta
     5521 aagccaatgc tttattttgg tcttctttgg ttggtgcatg tttgttaaag tcgtctgctt
     5581 ttttgatctc aggtttgaac gtaaattgat agccaataac aggttttccc cgtccttttc
     5641 cgtatttctt tttgattgtt agtcctttga agattgcagt tagttcttga cgtataggtt
     5701 ttataactcg tttatctata tcaggttgct tataactttt aggaatatct aataattcaa
     5761 gaaagtcttc tttggagaaa tatgcgaaac ctttggttct gtattgcttt aacagacgaa
     5821 acatagtctt tgcatagcca ctttgtagct cgttgaattg ttgtaaagaa tagcgtaccc
     5881 actcgtctaa attatttaac aaaggcagtg ctttttcgta aattcgtata tctacgtaag
     5941 gattttctac gtccccgttg attttaaatt ctgtaaacat tacaaacata tcgtaagaaa
     6001 gcccagactc acttctacga ccaaagcgta aagataagat tttttcataa gttgctttta
     6061 aatcttctac aaatcgtaca tttgcagttg ctttgtagtt acttaaatct tttagttggt
     6121 caaacgtaaa acgaactgtc ttatcccctt tttcacgcat tctagacacg atgg
//
LOCUS       DACCVZ010000125         6171 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.128, whole genome shotgun sequence.
ACCESSION   DACCVZ010000125 DACCVZ010000000
VERSION     DACCVZ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6171
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.128"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            114..959
                     /locus_tag="IVW63_002689"
     CDS             114..959
                     /locus_tag="IVW63_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7860918.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1240..2460
                     /locus_tag="IVW63_002690"
     CDS             1240..2460
                     /locus_tag="IVW63_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HAP7860919.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2457..5177
                     /locus_tag="IVW63_002691"
     CDS             2457..5177
                     /locus_tag="IVW63_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7860920.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5161..6105
                     /locus_tag="IVW63_002692"
     CDS             5161..6105
                     /locus_tag="IVW63_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP7860921.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2302 a          966 c         1202 g         1701 t
ORIGIN      
        1 cctattctta aaatgatgtt tgtacttact taaattaggt ataattagta tatgttttgt
       61 gagaaattta gacttacaat aagcagtgaa tttataatca acgtatagga gacatggatg
      121 aaatgaaact aattggtata gatttagacg gtactctttt gaattctgac cagagcatta
      181 gtcaaaaaaa tgcaagaaca atgaaacatt taccggaaga ctgttttcca ttcatttgtt
      241 ctggaagaga agtagaagac attaataata ttctcaaaaa atctggttta aggataccag
      301 cagtagggtt aaatggttct gttggatttg atggagaaaa aaagatattt gagtcttcct
      361 tcgataaaaa tgatgtaaaa aaaattgatt ctgtcctatc gaaatttcca accaaaatat
      421 atacaaatct cggaagttat gaatctcaga attataaaaa taaaatgaaa aaaatttttc
      481 acgaggtagg gagtgaattt tctatcaaag agctaaacta tgagcttgag tatgaaaaat
      541 ctatttgttc aatcccttat aataatattg aggaaattat agaaaaggat gctatcagca
      601 tttacaaatt ttttattttt attcctaatc gtcaattgaa agctaatata tttaaccatt
      661 tgaaaaagat gctaaatgtg tctgttactg aatcggcacc tgtaaatatt gaaatcgtac
      721 ctcaaaatgt atctaaaggt gtggtgtttg atcgtttgga atcaatctac aatttaaaga
      781 aacctttgag aatcgcgatc ggagatagtt taaatgactt atctatgttt gaaagtgcag
      841 atattagttt tgcaatggga aatagtcatc aagaaatcat gaaaaaagct gattatgtca
      901 ctgtttcaaa tgataaagac ggagtatctc aagcatttga aagaattctt accatataaa
      961 ctaattaagg tagtatagaa catagaattc taaatacgga aaaatggagc ataaattcca
     1021 gtacaaatag tacttcttca gtgtcaaacg aagcgaatat aacatagata tttaggattg
     1081 tgacaaaaat catgtcacaa tctttttttc gaataaactt attttttgaa gtcggccatt
     1141 tatcgtaatt tctttgcata atacgaacaa attttcggtt attgatgaaa aaaaacattg
     1201 aaaatggtat gataaaagaa aaaaaggagg aaatttttaa tggtgaaatt tatccatgcg
     1261 gcagatttac atatggatcg gtcatttgaa ggactgacaa ctcttgataa aactgtacag
     1321 gaaaaactat tgaagacgaa tctgaccgtt ttatcaaata tcattgaaca ggcaataata
     1381 aataacgttg attttgtttt acttgcagga gataattttc atcaaaatcg tccttcatta
     1441 aaaatacaga aacatttttc agaacagatg aaacggttag aaaagaacca tatacctgta
     1501 tttataatat tcggaaatca tgatttctat caaaaagagc ggtattggtt ctcctttcct
     1561 aaaaatgtcc atttatttac atccgaaacg gtagagacaa aaaaaataac gataaaaagt
     1621 ggagaaactg tctctctcag tggatttagt tatcgtcaac cgtggattca aaaagacaaa
     1681 gtgatggaat ttccttctag agaactcaca gattaccata ttgggttgta ccacggggaa
     1741 cctggcgtct ctcaaaaagg aaactatgct cctttccaac cctcaaagat gcaagaaaag
     1801 ggatacgatt attgggcttt agggcatatc catgtgccaa cggtcttaaa tgaaaagcaa
     1861 acaattgttt atccaggtgc gcctcaaggt catactaaaa aggaacaagc ttctacatct
     1921 attctactag ttgaattaag taaaggaagt tgccaaatac atccgattaa agtagcagag
     1981 gtctattgga agacaaagga aatatcattg aggaaagcaa gaacgacaaa agaggtcatt
     2041 gttcacattc gtcagcagct ttcaaaagta gaggatggat ttagtttaat tgagataaaa
     2101 ttaaaagatt atgaccatct caatacagat gttttggaac ggatacaatc aggagagcta
     2161 ttagactatt tgttagagga attctcagat aggataaatg atttctttat ttggcgtatt
     2221 tctctcatag agaatacttt ttatacgaag accccacttg ctgcttctgc taaattgatg
     2281 gaacagttat ttcaatacta tcagacacct caagatttcc aacaaatttt aaatgaagta
     2341 tatagtcatc aagaagcggc tagaatattg agcgaactgc cggaatatca agaagaaaca
     2401 cttgaaaaag ccaagcagct gcttaatcaa gattttttat ttgaggagga tcaggaatga
     2461 agattttaag gatcgagatt gctgcttttg gaaaatggcg tcaaaaaagt tttgactttt
     2521 attcaggcaa tcagctgatc tatgggggaa acgaagcagg aaaatcaacg atttatcaat
     2581 ttattcaagc aatattattt ggtttccctt caaaaggccg taaaaaaaag gattatacac
     2641 caaaagacgg ctcagcctat ggcggcaaaa tatggcttaa acatcctgta tatggtgaat
     2701 ttgctgtcga gcgctacaag cagcaaaatc gcggaaaatc gaaggtgtgg ctgggggatc
     2761 aagtgggaag tgatgagtta ctagaaaaac tgatcgcacc tttgacgaaa gagttattcc
     2821 agcaggtatt tactttccag caagagcagt tgatggaact agatcatttg agagaaaaag
     2881 agctacatga tgcgctgatt tctttaggca tcacgggcag ttctcaagta ttccaaaagc
     2941 ggcaagaata ttatcagaaa gcacaacaat tattcaagaa aaaaggccaa aaattactaa
     3001 tcaatcaaaa attaaatgaa tggaaagagc tgcaagaaaa aattcatcaa aaacaagaac
     3061 aggaagctta ttttggcaag ttgatccaac aagaacagga atacgagtcg caacagcagc
     3121 agttattggc acaattaaaa gaggcgaaca aacaattttc attagccaga cagcaagaac
     3181 ttaatttttc tttatatgaa gaatggcaat ctctcaaaaa aaacagcact acaggtcttc
     3241 ctgatgagca acttctttta gatctggagt ctttctccaa acggtatcag caaacaaatg
     3301 agcgtttgga agaattagaa gcaacactgg aaaagcatag cgggatggat cagcagtcag
     3361 ccagatatta tttttattta gagcaggagc aggaactaaa agatctccag caacttcaat
     3421 ttacagcgga acaattaaac gaagaatggc aaagattaca aattgagact agagaaacaa
     3481 attcagaatt gaagattttg gaacaaaggt ggcattggca gaaaaatccg ttaccggaag
     3541 aatttttata tgaagaagaa tggaagcatc ttctggctga agaaagaagg attgctgatc
     3601 tagaaagcca gatttctgtg cgtctccaaa tagctaaaga acagcaagag atgattgaag
     3661 cagaagtgaa tgacttggaa gagacctatc cagcattatt acaaaatcag tcagagatag
     3721 caccagtctc ttcatctaaa ccgtatatgc tgatggctgg cggagcaata atcattgcag
     3781 gtatatttgt accaatgccc ttgaaagtga tccttttact aattggtgca ggcatgattg
     3841 gctatttctt ctacaaaagg caaccaaaaa ttaaaactaa aaatgatttc tctgagataa
     3901 aaggaatgtg gcaagaaaaa ctaggacaac ttgatctagc cttagctcaa ttagctgaag
     3961 cagaagaaaa acaaaagaga actggagaag aaaaacagat tcttcagcaa gaagtatatc
     4021 gttttgcgga tcatcggcac ttaggaaaga tggatacgct caaactcatg aaagaatatg
     4081 gacaggaagt catagattat cagaaattat atggcgtatt tgagcggaaa cataaaagag
     4141 aacaggaaat acaagaaaaa ctacgacaaa tcgaccaaaa atttgagttt gttaaagaat
     4201 ggttaccgat acaagataag acaatttcag aaaaaatggt attgctttcc cgttttatac
     4261 aagagatgga acagatgaaa tttgccagaa gctatcagca aaatacttta ttgaagcaag
     4321 aaatcaatca attgaaaaag aaacaaaaag tatggataca agaatacagc gaacaattga
     4381 ctcaagcagg cttatcttat ccttcggaag tacctgtctt tttacaaaaa gccaaacaag
     4441 ccgaacagca gatgaaaaga tacaatgaat tatcggaaat gcttactcca ctatttcctg
     4501 aagagctgac aaaagagaaa ttatctgtaa gactgcgcca actgaaagaa aagcaatccc
     4561 aactccagca agaagaaaaa gaagcaagtg aaaatcggca acgactccaa cttcaagtag
     4621 aagagttgca aagagacggc acattggacg aactttatca acaagctagc cggcaaaaag
     4681 caaaattaca ggaattactg gaggaatggg gagcacttga aatcgccggg acattcttag
     4741 gtgatctttc aacagagatg agtgaaagac aattacccca gttgttaaga gcagcaggtg
     4801 attatttagg tattttaaca aaaggaaatt atcagaagat attactgaaa aatgatacac
     4861 tgactttaac agacggatat acagaatttc ccatctatga gttatctaca ggtacgaaag
     4921 atcagctgat tatggcgatg agatttgctt acctctcatt agaagctaac cgttcgatat
     4981 gcccgatcat cattgatgat ggctggcttc attatgatca tcagcgaaag tatcaattag
     5041 ctgaactttt agctaaattt ggagaaaagt atcaaataat ttgtttttct tctgataaag
     5101 aaatggtaag ctattaccat gagatgaacc aaatcgtaaa acaattagaa ggagcaaata
     5161 atgaaaaaaa ttcgtgattt agtaatcgat gagcagtttg aacaatttgt cctgatcaaa
     5221 agtgcagatg taagaatcgc taaaaacgga aaaaaattta ttgcttttac tttccaagat
     5281 acttcaggta ctatcgatgg taaatactgg gatgcttcgg aggaggaaat caataaattt
     5341 acagccggca cagtcgtttt tctaaacggt aaaagagagg tttatcaagg aaaccctcaa
     5401 gtaaagattc ttcatatgcg cttaacaagg gtagatgagc caggagagcc tagtttatac
     5461 atggaaagag cccctttgaa gaaagaagaa atggaagaag aaatcaatca attgttgttt
     5521 gagatcacca atgcgcattg gaatcgtatt gttcgctatc tacttaataa atatcaaaaa
     5581 caattttttg agtttccggc agcaaaaaga aaccatcatg catttgccag tggattagct
     5641 tatcatactt tgacaatgct tcacttaggg aaatcaatcg ccgatgaata tcctgagctg
     5701 aatcgagcat tgttgtatgc tggtatcatt ttgcatgatt taggaaaggt gattgaactt
     5761 tccggtccta tgtcgacaga atatacgctt gcaggaaatt tgatcggtca tctggtattg
     5821 attgacgaag aaataactaa agcctgtctt gcgttgaaaa tcagcgaagc tgacgaagat
     5881 gttctcgtat tacgtcatat ggttttagca caccatggct tattagaata tggctcacct
     5941 gtacgtccaa gaataatgga agcagaaata ttacatcaaa tcgacaatat cgatgcttcg
     6001 atgcagatga tgttgacttc gattcgtcaa acagaaccag gaaaatacac cgatcggatt
     6061 ttcggtatgg acaaccgaag tttctatgta ccaaaagatt tatagcaaaa atttattttt
     6121 ttcattcaaa acaaaaaaag cgagacataa gtcttcgctt tttttgtttt c
//
LOCUS       DACCVZ010000126         6024 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.129, whole genome shotgun sequence.
ACCESSION   DACCVZ010000126 DACCVZ010000000
VERSION     DACCVZ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.129"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(122..502)
                     /gene="yajC"
                     /locus_tag="IVW63_002693"
     CDS             complement(122..502)
                     /gene="yajC"
                     /locus_tag="IVW63_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAP7860922.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(599..1744)
                     /gene="tgt"
                     /locus_tag="IVW63_002694"
     CDS             complement(599..1744)
                     /gene="tgt"
                     /locus_tag="IVW63_002694"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAP7860923.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            1962..2660
                     /locus_tag="IVW63_002695"
     CDS             1962..2660
                     /locus_tag="IVW63_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAP7860924.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(2828..5467)
                     /locus_tag="IVW63_002696"
     CDS             complement(2828..5467)
                     /locus_tag="IVW63_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP7860925.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
BASE COUNT         1694 a         1323 c         1106 g         1901 t
ORIGIN      
        1 gacacacccg attattcaat attgagcaat atatcccatg ctcttatctc tttctttttt
       61 gaataaaaaa tgaggtagga catctttctg ccctacctcg tctttaaata agctttgata
      121 cttatttttc ttccttctct tctgtctctt ccagcgtttc tgttgtttca gtttttactt
      181 caactgtctc agctggttct tctgttgttt caacagtagt cgttgcatca tttgttacga
      241 cagtccctgg tttgaccgtt ttgattgctg cacgatcgta ctcaaggaag atcccttcgc
      301 agtctaaaac aactgtccgt ttgtcattgt cgatttctga aacaactcca tgtaatccgc
      361 cgatcgttac gactgaatca cctggtttca tgctatctaa caagttttga cgttcttgct
      421 gttgtttctt ttgcgaacgt gacataaaaa accacattgc taatagcgcg ataaacatca
      481 caagcattgg taatgttccc atttttttca cctcactaat tctgtatcta caaaaaacac
      541 tttagcagaa aaatgctgat aacactagtt ttttacttaa tttttaaaag attttccttt
      601 agaagctttt tgcgttttct ttattgaacc cgtattcttc aaaaaaggct tctctaaatt
      661 caagcaaatt atcatccatg attgcttgac gtacttgttt cattagattc aacaagaagt
      721 ataaattgtg gtaagaagtc aaacgaatcc caaatgtttc atcacatttg atcaaatggc
      781 ggatataggc acgtgtatag tttttacatg tataacaatc acatttctca tcaattggac
      841 ggaaatcatg ggcatatttc gcatttttca ctactagacg gccttgagaa gtcatacatg
      901 tgccatttcg agcgattcga gtaggcaaga cacagtcaaa catgtctact ccacggataa
      961 caccatcgat caatgaatca gcagcaccga cacccatcaa gtaacgtggt ttgttttcgg
     1021 ggatcaacgg tgtagtgaat tctaatacac gattcatttc tgatttaggt tccccgacag
     1081 ataacccgcc gattgagtaa ccagggaaat ccatcccgac tagatctttc gcgctttgac
     1141 gacgaagatc ttcaaaccct gctccttgga tgattccaaa taatccttga cggtctggat
     1201 tagcatgagc tttcaatcct cgttctgccc atcgagacgt acgttctact gattttttca
     1261 cgtagtcgta actttcatcg aatggtggac attcgtcaaa actcatcatg atatcagagc
     1321 ccaatttatt ttggatgttg attgcttttt ctggtgataa aaacatacgc gaaccgttca
     1381 agtgattttt gaaatgcacg ccttcttctt cgatattccg catatcactt aatgaaaaaa
     1441 cttgaaagcc gcctgaatct gttaaaatcg gttgatccca gttcataaat ttatgcagtc
     1501 cgccagcttc ttctactaag tcttcaccag ggcgtagcca taaatgatat gtattactta
     1561 aaataacgcc agcacccatt tctttcaact cttctgggga cattgttttt actgtagcta
     1621 atgttcctac tggcatgaac attggtgtgg ggaaagttcc gtgtggcgtg atcaattccc
     1681 ctaaacgcgc gccagtatgt ttttctttct tgattaaacg atagcgaatg gcaggttgcg
     1741 tcattcattt ccctactttc tatataaaat atcttgacaa ctcccaccat cataatcgtt
     1801 tcaagtgctt tttgcaagtt ccctcggctt ccttctactt tatttaatat tctttttttt
     1861 atcctttttt tatgaataac aaaaaaaaga aaaacattat gacagaaata ttttttgata
     1921 catggtatat tggtgttatt aaagaaaagg agggaaaaat catgcaatct tctgcagaat
     1981 taaaacgcca agcaaaagag agtctaaaag gacgttgggg acaagctgtt ttactaaatc
     2041 taatccctac attgattggt attgctacta ttcttcttat tatgattcct attatcttgt
     2101 ttgccaccac catatatgat ggatcagcga gcgtctcaga agcgacaact tcaggaggcg
     2161 gtagttcagg aggcggtggc ggaattattt ccagcatcat tagcgctttg ttcatgagcg
     2221 gtatttcttg gacttatctt gatattttac gtggacaaaa agatcagatc gaaccattca
     2281 aagatgcatt tcgtggattc aaaggtttgt ttatcggcgg agtgatcagc ttagctgtgc
     2341 tgatctcgat ctttacaaca ttatggggtt tgctattagt tattcctgga atcattaaaa
     2401 gctattctta ttctcaaagc tattttattt actacgatat cgtccaagaa acaggacaaa
     2461 cacctaaagt actggatacg atcactgcaa gtcgaaaatt gatggatggt tataaaggac
     2521 aacttttctg gttagatctt tcatttatcg gctggcatat cttagcatta gcaactgctg
     2581 gtattggtta tctatggctc agcccataca tttctgcaac aaaagcagca ttttatgaac
     2641 aattgccaaa agatatttaa aagagagtgt gacttgtgac cgagggggtg gcaggagaac
     2701 accgtttatc gagaggcagt aaaagaaaca ttcagcccat tagcaaaaag gaggtgtgac
     2761 aacattcatg tcacacctcc tttttgtata gttccagtaa aaagaaaatc aacttagaaa
     2821 cagttaatca ttcctcttct tctgcttccg gtaatcgatg gaacttgatc agttcattca
     2881 ccgcgattgg tacgatagat aaaatcccta ccaagaacca gtgattcaaa ctgatgtgta
     2941 ctaggccgaa tagttcttgc gtaaatggca gcaaagcaac agccgttgta atagctaatg
     3001 ccagtaacgc catttctacc aaagctttat tggtcgctaa attgactttg aagatcgatt
     3061 ggctgctgcg tacattgaac acatgcagaa tcgatgaata agctaagatc aagaatgcaa
     3121 cagtttgacc gacatgctga cttgcgtcta cccatgggct gatagtatcg acataactac
     3181 ctaaataata accaaacaag gttacgatgg tgaagacccc tgcatttatg gcaatttttt
     3241 gcaataaacc tcgagcaaag atcccttcat ttttcggaat gggtggctga tccatgatgc
     3301 cgtgttccgc tggctctctt cctaaagcaa atcctggaag tccatcagca actacattga
     3361 caaacagtag ttgcacagct gtaaatggtg ctccccatcc taacagcatc gcaatcaaaa
     3421 caataaagat ctccgaaata ttacagctta gcaaaaagtt gatagcttta cgaatattct
     3481 gataaaccga acgtccttga ctgacagcgt ctacgatcgt cgcaaagttg tcatccgtca
     3541 aaatcatatc tgcggcactt tgcgccacat ctgttcctgt gatccccatg gcacacccaa
     3601 cgttacttgc tttcaacgct ggtgcatcat tcacaccatc cccagtcatc gctacgactg
     3661 cacccgtacg ttgccaagat ttgacgatcc ggatcttgtc ttctggcgtt acccgagcat
     3721 agacagagag agctttgaca cgcgcatcta attcttcgtc tgataattga tgcagttctg
     3781 atcctgaaag tgcttctgac ggatcattca agatacctaa ttctttcgct atggcactgg
     3841 cagtcaccac atgatctcca gtgatcatga ctgttttgat gccagccttt ttcgctcgct
     3901 tgattgctcc tttactttct ggacgtggtg gatcgatcat tccgatcaga ccaatcaaac
     3961 gtaagtcttt ttccagtgct tcagaagaaa tatcttgcgg ttcttcgtca taagtagcat
     4021 aaccaacagc aatcactctc agtgcccgtt taccaaagcg atcattaacg atcgccgctt
     4081 gttctacatc gcctgaacta aagcgcggag caagaacatc gaatgctcct ttggtgattg
     4141 agatgtattt ttcgcccatt tggtgaactg ttgtcatcat ttttcgttca gaatcaaaag
     4201 gaagctcgtt tactcgtgga tatttttctt ctaattctgc ctttgtatga taattctctt
     4261 caacagccct tacgatggct acttctgttg gattaccttt gataacaagg tcgtcatctt
     4321 cttgctcgac cgtcacatct gtacatagtg cagccatttt caatatttcc atcgcgctgt
     4381 tcgtcattga atcttcgata ttcgttactt catcttcttt gctccatacc cggcggacgc
     4441 gcatttcatt ttgtgtcagc gttcctgttt tgtctgagca gataacatta gcggttccta
     4501 gcgtttcaac tgctggcaac tgtcggatga tcgcatgttt cctcgccatc ttctgcacac
     4561 cgtatgcaag tgtcaacgta acaataacag tcaaggtttc cggtacagct gcaacagcca
     4621 aggaaatcga agtcatgaac atctcaagga gtggttctcc ttgcagttca ccaatcacaa
     4681 atactaaagc cgcagccgct aaagcgatca tactgattcg tttgcctagc tgattcaatc
     4741 ggacctgtaa aggtgttttt tgcatagtat tttcgttcaa aagatccgcg atcttaccca
     4801 tttctgtagc catgccaatg gcagtgacga tcgctttccc acgacctgca gcaaccgtac
     4861 atcctttaaa taccatatta agttggtcac ctaatgactc atcttcttca gcaataaatg
     4921 ctgcatcttt ttcaactgct tcactttctc cagtcaacgc cgattcttct acacgtaatt
     4981 gtgatgcttc gatcaaacgg gcatcggcag aaatagcatc accggactct aaaacaagaa
     5041 tatcacccac taccagttgc tctgactcaa cagtggtcac tttgccgtct cgtatgacag
     5101 ttgccgtttg tttattcata tcttgcaagg attccagtgc tttttctgcg tttccttctt
     5161 ggacaatcgc caataccgag ttgatcacaa cgatagcgat gatcagcagt ccttcaaata
     5221 aatccccatg ttctgtagca aatgcggtat aaaaggaaat caccgctgct acaagaagga
     5281 tgatcgttgt aaaatcggac aagcttcgaa agaatttttt gatcatcgat tctttcggcg
     5341 cctcatcgaa tttattcaat ccctgctttt ttcgccgttc atccacttct tgtgaagaca
     5401 acccagtatc tggatctgct tctgttacct tctttacttc ttctattgtc tgcttgtatt
     5461 cttccatcct attcctcctt taaaatcttc gtacaaaaaa aggtacttat tttactataa
     5521 catccttttt ttatttactt caaataaagg gcttatcgat tatttgttaa gaaagcgtaa
     5581 aatttaaagt gcttatattt gcaaacgcta ccaaaggatg ctattatata gatgtaagga
     5641 aggaggatac catcaaatag acagaagaat ttctcgatag aacagtgtaa gcaaacaaag
     5701 ttgttagaag tacaggtttc acccagacat gcgtgtagag tacaaaccta taaatagtga
     5761 atgcgtatgg atgtttggat cacgaagtat ccgaaacaag aagtaatgcg atacgtaaca
     5821 attgaataac gtaaacgtct gaaaattgaa taggaacaag agatgtttca aatgttgaag
     5881 atgtaacgaa aacaaaattt ttgtttaaca tgaagaaatt caacaccgtg ctttgcatgt
     5941 atgatggaaa gttacaatca tttctgttta tttgaatcct tccgaggtac aagaaagccg
     6001 agcttatcga gagctcggct tttt
//
LOCUS       DACCVZ010000127         5903 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.130, whole genome shotgun sequence.
ACCESSION   DACCVZ010000127 DACCVZ010000000
VERSION     DACCVZ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.130"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(364..1482)
                     /locus_tag="IVW63_002697"
     CDS             complement(364..1482)
                     /locus_tag="IVW63_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860926.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1953..3260
                     /locus_tag="IVW63_002698"
     CDS             1953..3260
                     /locus_tag="IVW63_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAP7860927.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3379..4578
                     /locus_tag="IVW63_002699"
     CDS             3379..4578
                     /locus_tag="IVW63_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAP7860928.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4605..5873)
                     /locus_tag="IVW63_002700"
     CDS             complement(4605..5873)
                     /locus_tag="IVW63_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HAP7860929.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
BASE COUNT         1813 a         1251 c         1058 g         1781 t
ORIGIN      
        1 taaacggtgt tccagaagta gcttcttcgg aaataagccg aaatttcaca aaaatttgag
       61 aaataatttt tgtcaatctc ttcttatttc ttgaagctga ccacttctgt cacaacctct
      121 tccttaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaccaaa caaaaaatat
      181 gaagagctat ttttgcttgc tgttcttatt acttgatgca gaacagcttt ttcacaacct
      241 ctcatacacg gtgtttaatc agctgacctt cggtattagc tcaaaaaacg gaaaaatatg
      301 tgaaactatt tttccgtttg tttctctaat actcaggtca aaacactgat ttcacaacct
      361 cttttaataa cgaagaatcg ctgtcagact cttttcatct ggcgcatctt tttgatccaa
      421 aataaacact ttcccgccat taatgatcac atcatctgct aatgcattca acacttgacg
      481 ccgatcatat tctgtttcag gatcttcacc gaaaccatca gctaagtttg acgtagcgat
      541 aaataaatgt gacacttttc cttctttcgc agctggaacg atatcaacta actgatcgat
      601 gaatttctta tctaagagtt tattgtattc ttttgattct tgagctgcga gttcacttga
      661 cagcttcttc gccccttctt cgatatctct aaaggatagc tgcgcaggag aagcagaaat
      721 cgcaacgtct gcacaataat agggattttt agcaattttt ttgaacatcg tctgattttc
      781 tggtaatgca aataaataaa tcggccattg ttcaggattt tcgaaagaat ccttcaagta
      841 cgtatcaaca gcttggtaat agttgaccca atcgatctct acttcttcat cttttggatt
      901 tacgccatgg aaagttactc catctcgggc tccgcctcct ccattagaag agaagttcaa
      961 accgccacct gtcagttcag atcccaatgc agtaacgaca tcaaccggtg ccccttctgg
     1021 tagagatact tcttttactt gtttgttgct gacctcatac aatttcatgg agtcgcggtt
     1081 caatcccaat aaataataag aatagttgaa ctgcccattt ttgataatag ccagtaaata
     1141 aggaagatca cttacatagt attgatcgtc taccgggata ctcaaacgat ggatataggt
     1201 ctggtcagca gttataatga ccgctacact cgtagttgca ctacgccaaa acgaaggatc
     1261 tcctaacaaa ttttcaattt tttcttggaa cggggaccag tcatgttcgg aatatttttt
     1321 ctcaaaacgt ttctttgctt ctttcgcaaa atttttgaat ttgatctgat ctttttccac
     1381 atcttgatgg gcgacatgcg tattcagcat gatcgtgacg aatggtcctt tagcgccttc
     1441 tgaagtcaat tgtgtcaata attctttatc cttttttgcc ataaacgtac ccctcctaaa
     1501 aaaatcattc ctttgtttct atctaaagtc taccacaaca ctatttttcc atacaataaa
     1561 acgtatctaa aaaaataaaa cggtttctac ggttttaaat ttagctattt ttttaagtta
     1621 tcttcataat ttcctcaatt atttagcccc agtcttcaac tattcttcat gaaatgctga
     1681 taaactaaga aaaagaataa aagaggtgga tcttatgcat ttgattatga ttttcagttt
     1741 attaagtatt atcagtttat ttgctttcag cgcttcccgc ttattagatg cggaaacaca
     1801 gcctattcct gtaaaagtac gtaaaaacga ccgctaaact tccataacgc gcgttcttat
     1861 cctaaagttt tttcagaaac attgaaactc tctcccctct ctgataaaat tttaatttgt
     1921 agcgaaacaa attaattaca aggagatcgg atatgtccat aaaaaaaaca cgtctagtcc
     1981 tattattggc tagtctcatt ctttgccttg cttcttttct accagctgtt gctgtgcaag
     2041 ctgaagatac gttcaaagta aatgcaaaag cagcttttgc tgtagatgcg caaagcggta
     2101 agattcttta tgatcaagat ggagaaaaaa ccatggggat cgcttcaatc acaaaaatca
     2161 tcggtcttta catcgtcctt gatcaagtaa aagaaggaaa actgtcatgg ggtgataaag
     2221 tttcgatttc agattatgca gaaaatttga gtatcacccc agatttatcg aatgttcctt
     2281 tgcataaaga aaacacctac actgtcaaag aattattcga ctctgcaatc atccagtcag
     2341 ccaatgcttc aatggtggcc ttggcagaaa aaatctctgg cagcgaagct aaattcactg
     2401 aacgaatgaa agaacaattg aaagattggg gaatcaaaga tgcaacaatc gttaatgcat
     2461 caggattgaa caactcttat cttggcgaaa accgaccaga aggcactgga gaaaacgacg
     2521 aaaatcaaat gtctgctcaa gatgtggcca tcgttgcccg ccatttgatc ttggatttcc
     2581 cagaaatact ggatgtatca agtactacga cccaaatgtt tggcgaaaat acgcaatcac
     2641 cagtggaaat ggtcaactgg aactggatgc tcccaggatt cgttaattac aaggaaggcg
     2701 tggacggatt aaaaactggt acgactgagc ttgcaggtgc ttgtttcgtt ggtacgatca
     2761 ctaaaaacga tcaacggatc atcactgtcg tattgaatgc ggacggccat gcggaaaacc
     2821 cgagtgcccg cttcaatgaa acagaccgtt tgatggacta ctgctatgac aattggtcag
     2881 aaaaagagct cggaaaagct aacgcaagta ttcctagtct aaaaaccatt gatgtaaaag
     2941 acggaaaaga atcaacagtt cctgttgtgc ttaaaagccc tgtaaaagta tgggtacgaa
     3001 acgatatgga tactggcaaa ttaacgatca cgccaacact tgacaagaag caagtcactg
     3061 acaatgagat ccaagcacct atggataaag gtacaaaaat cggtaccgct acgatcacct
     3121 tggcagacga taaattaggc tatttagaag acaacaatgc accatcaaca gagatcatta
     3181 cggataaaac agtggaaaaa gcgaatatat tcgtgattgg ctggcgacgc gtcgcagaat
     3241 ttttcggcaa cttgttttaa ttgaacaata agaaaaacat ctttccatcg gaaagatgtt
     3301 tttttgcttt ttctagttta aataacagct tttttcatct attttcgtta tactgtataa
     3361 gaaaaaggag ttgaatttat gaatctaacc agagatctga tctttttagt tctctatctt
     3421 attggggtat tctctatcgt ttattggcga aaacagaaga aggatccttc cttgttcttt
     3481 tacggcagta cgtggacatt tacggtaatc ttaacttatt ttgtcgtgtt ggaaattttt
     3541 tattcgacct tttatttttt gattccattg ttgttcttta gtatctttgc tttttcttat
     3601 ttcacagaaa aacgaaggct actgaatggt cttttattca atgttttact catcagtttc
     3661 ggcatctact tgtttgtctt gctgtatgaa acgcaaaata tttttcttgg cggactgatc
     3721 gccttgatca cgattccatt gctacttgtc cttttatttg gtatttatgg attgattgtt
     3781 tttctttttt ggaacggggt cacagtttta cgtagagaat cgcattcatt agctaatctt
     3841 ttaacgttga tactagccat ttttcttaca ctgtttcttg tttttgactt tttcttgtta
     3901 aaatatttgc cgcaatggat aaatgctttg tttttctgcg ttcccctgat cttgatctat
     3961 ctatttatcg tattctacaa ctttttgact gtctcattct tgtatcagtt caaccggcct
     4021 cgatacaatc aagacttcat cgttgtgtta ggcgctggat tgatcaatgg agaaacagtt
     4081 tctcctcttc tagccaagcg aatcaataag gcaattgctt tttatcgggc tcaaagccgt
     4141 gctacattaa atccgcccat cttattgatg tctggcgggc aaggagcaga cgaaaaagta
     4201 ccagaggcca ttgcgatgaa acaatatgcc atggaacaag gaatccctga aagagacatt
     4261 cttgtcgaaa ccaattcgac aaccactttg gaaaacatgc tctattcaaa ggaaatcatg
     4321 gatcagcaaa tgaaagggcc ataccgcgcg atctttagtt ccaacaatta ccacattttt
     4381 agagccggtc tttatgcgcg gcaagccaaa ttgaaagcaa atggtattgg tgcaaaaaca
     4441 gctttctact acttgcctaa tgcgttttta agagaatacc tcgccatctt gatgatgaac
     4501 aaaaaaagac atatgatcat ttgcggattg cttttcgcag gctccgcatt cttatcgctg
     4561 attactttac ttttctaaaa aaacaaggtg tgacaaaaca tatgtcacac cttgtttttt
     4621 tctttcattc tcttaactat tggcaaaaag agtatccctt ttttgaccgc tacttgctga
     4681 gcagaataaa taccgctgtt gcctgaacac ataaagctga tcaagcagat cataaagaag
     4741 tatactgccg cttgtgaacc gaacaattcg atccccatca caaagcaggc aatcggtgta
     4801 tttgtcgcac cagaaaatac tccgataaag cccaatcctg caagaaaagg aacagaaaca
     4861 tggagcaaag gcgctagtgc tgcaccaagc gttgcaccaa tttcaaacaa tggtgtcact
     4921 tctccccctt gatatcccgc gcctaaagac aaaactgtga agaataactt cccaataaaa
     4981 tcatagacat gtgcctgtcc attaaatgat tcttgaagta acggaagact caatccgaga
     5041 taacgttgtg tttgcaaaat caatgctgct gccacaacta cagctccacc tatcgtattt
     5101 cgacaaacag gatgaggaat ccattgtgca tatcgcgctt ttaaaaagac gatcgaacgg
     5161 ctgaataccc aaccaatcaa accaaaagca atcccagcaa caaaaacttt gaagaacagc
     5221 aacatactcc attcaggaat cacacccatt tggtaatgta gatgagaaac accatagctt
     5281 tctgtcatga aatttgcaaa cagtgcagca aagaagctag ggaagatcgc ttctgttcgg
     5341 actttcccga ttgccaacac ttctaatcca aataatgttc cagctaaagg tgtgccaaat
     5401 acagaactaa aacccgcact gattccactg ataatcaaga tttcccgttc tgatttatcc
     5461 aatcggaaca aacgtgccgt attatctgct aacgctcccc ccatttggac tgctgttcct
     5521 tcacggccaa cagatccccc aaataaatgg gtagttatgg ttccaaacag tgtaagtgga
     5581 ataagccgca acgggatttt ttcttctcca ccatttcctt gatcgatcac taagttgttt
     5641 ccacgactag aaagtccgcc gtgatacgca tagagataag caaaaagcgc accactaact
     5701 ggtagtagac aaaggagcca aggatgtgat agtcggatat ctgtcacaac tgtcaggcta
     5761 tttaagaaaa aagcagacaa gctccccatg aatataccga gaatcgctgt gatcaccagc
     5821 cacttcagca tatacactaa aatgcgtact ggactcggta attgtttttc cataaaaaat
     5881 tcctcctcaa taaaaaaacg cct
//
LOCUS       DACCVZ010000128         5897 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.131, whole genome shotgun sequence.
ACCESSION   DACCVZ010000128 DACCVZ010000000
VERSION     DACCVZ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.131"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(123..581)
                     /locus_tag="IVW63_002701"
     CDS             complement(123..581)
                     /locus_tag="IVW63_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAP7860930.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(594..1919)
                     /locus_tag="IVW63_002702"
     CDS             complement(594..1919)
                     /locus_tag="IVW63_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HAP7860931.1"
                     /translation="MKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDEER
                     NMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKIPL
                     KHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVRRK
                     YPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREIMP
                     EIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVVEH
                     TDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLNDDR
                     RRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAVEK
                     LLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(1936..3348)
                     /locus_tag="IVW63_002703"
     CDS             complement(1936..3348)
                     /locus_tag="IVW63_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7860932.1"
                     /translation="MNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADDMLNIPVIGAA
                     GNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMDPEVNMGIFGG
                     IISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLGFIWPLIQIGI
                     DNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSPSKEVFRGEMT
                     RFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMGSGAGTSFIAN
                     ITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVDYLINFRIATN
                     AILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEETELGLASKNYE
                     YMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISGIIKPTEKNYQ
                     IIIGLEVTYVMAEFNKLLEE"
     gene            complement(3365..4129)
                     /locus_tag="IVW63_002704"
     CDS             complement(3365..4129)
                     /locus_tag="IVW63_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HAP7860933.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(4233..5108)
                     /locus_tag="IVW63_002705"
     CDS             complement(4233..5108)
                     /locus_tag="IVW63_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7860934.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(5363..5447)
                     /locus_tag="IVW63_002706"
     tRNA            complement(5363..5447)
                     /locus_tag="IVW63_002706"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5411..5413),aa:Leu,seq:caa)
     gene            complement(5465..5536)
                     /locus_tag="IVW63_002707"
     tRNA            complement(5465..5536)
                     /locus_tag="IVW63_002707"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5502..5504),aa:Gln,seq:ttg)
     gene            complement(5546..5618)
                     /locus_tag="IVW63_002708"
     tRNA            complement(5546..5618)
                     /locus_tag="IVW63_002708"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5583..5585),aa:His,seq:gtg)
     gene            complement(5680..5764)
                     /locus_tag="IVW63_002709"
     tRNA            complement(5680..5764)
                     /locus_tag="IVW63_002709"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5728..5730),aa:Leu,seq:caa)
     gene            complement(5785..5855)
                     /locus_tag="IVW63_002710"
     tRNA            complement(5785..5855)
                     /locus_tag="IVW63_002710"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5821..5823),aa:Cys,seq:gca)
BASE COUNT         1805 a         1254 c          897 g         1941 t
ORIGIN      
        1 aaaaaattcg ataattaaca aaaatcaaaa tgattaaatc tagtgattga aacatatcat
       61 ttcaaaaaaa ttttgtaaat tcacccataa atatcaccct atttaacttt tttcatcgta
      121 cactaaaatt caaaacaact atctttaatc tttacttctt ggttttgttt taataaattt
      181 ccttcaaaaa tgcctggaga aactacaatg atcaccgtat ctttttgtgc ttgctccaac
      241 ttcttcaaat ctataatagc taacagtgtc ccttctttta cctcctggtt actttcaacc
      301 cgtatctgaa acggacttcc ttcgagttca actgtatcta aacccatatg gatcagtatt
      361 tttctgccag attcactttc gatcgttatg gcatgtcggg taggaaatat attatcgatt
      421 attcctttaa ctggcgcatg gatatatcca tcatgattcg ttatagcgta tccaactcct
      481 atcatttttg aagaaaagac ctcgtctttt actgctgtta atggaataat ttgaccacta
      541 gctacagctt ttagaatgtt tcttgtttta aagaaatgca ctttttatca cctctacttt
      601 aatgctggcc aatatttttt gtttactttg atcatttcat ctagtatttt ttttgcgact
      661 ctggcatttg gtacggtttg attcaatgta aatgcttgta aagctttttg ataagaacct
      721 tcaaagtaag catctactag taacttctct actgcaactt gtgcctccat caatccttta
      781 tgaaaatcac tgattggttt tcttagtgta attggctcca caccagttgc accaacatat
      841 gccggtattt caacaactgc atctgaccgt agattcggaa tcgccccttg attaggaacg
      901 attagcataa agcgacgacg atcatcattc aacaaggaaa tagctatatc gacgatatat
      961 tgtccatgct ccccaaaatt aaagttcaat acttcttcca caataccgcg gcgtatttta
     1021 tcagccattt ctttggtatt tttctctcgt ccatccatga ccatattagc acgtgtatac
     1081 tctttgtcag tatgctcaac gaccatatca ggatataagt aatactctaa gtaattattc
     1141 gggatattac ttggaaaatt tttcgtgatg actgacatca tttgaaaggt tttttgccaa
     1201 gttttatctc ctatattaaa atcggcgact tgcatttctt ttgttattag tttttcaata
     1261 atctctggca taatttctcg ttgcaattct ttatcataaa tcgatgtata ccagccaaag
     1321 tggtttaaac cataatacgt aacgatccaa ttcttacgat cataaccgta attcactgca
     1381 atcgtttctt caattgaaat agtcatatca caggcattaa tcatttttac attcggatat
     1441 ttacgacgaa cagcttcaga aacgatcgac tctggatttg tataattcaa aatccatgct
     1501 ttgggggcat agtcttgtat atgatcgaca atttccaata aacctttgat tgagcgcatc
     1561 ccataagcaa atcctccgag tccacacgtt tcttgtccta ctaatccatg tttaagtgga
     1621 atcttttcgt ccttttctcg catctccaat cctccaacac gaatttgtga gaaaacaaaa
     1681 tcgcatcctg taaaagcaag ctttggatca tccgttgcac gaatgcgaat atttgaaaaa
     1741 ccttttcttt tcagcataaa tttaacaatc aagtacatat ccatatttct ttcttcatca
     1801 atatcatata aacgtatttc agataatggc aaccgttttt cattgttcaa aatggcttga
     1861 acgattcctg gtgtatacgt actcccgcct ccagctatag tgataatctg ttttttcatc
     1921 atcatctttt cctttctatt cttctaataa tttattgaat tctgccataa cataagtcac
     1981 ttctaagccg atgataattt gataattttt ttcagttggt ttaatgatcc cgcttatccc
     2041 taattgcttg attcgctgtt cctcgaccat ggtgggatcc actacctcta cccgtaggcg
     2101 tgtattacaa ctatagacat ccaggatatt ggcttttcct ccaaacgctt gtagcatttt
     2161 tgttgccata tattcataat ttttacttgc taaccctaac tctgtttctt ctaaggttac
     2221 ttcattgcca aactctgcct tagcttcacg tcctaatgtc tgaatgtttc tcttattgat
     2281 caaataataa aaagtaacgt aatacaaggc aaaaaagaaa attccgattg gaagaatcaa
     2341 aatagcattg gtagcgattc gaaaattgat gagataatca acaatacatg ctccgaatgt
     2401 aaaaccaatt cgtatattga ataagtaaca gacaatccct gctaaaccgg caaaaagtgc
     2461 atggatcacg tacaacatag gagaaagaaa catgaaacta aattcaacag gctcagtgat
     2521 atttgcaata aatgaagttc ctgcaccgct tcccatgatt cctttgacca tctctttatt
     2581 ttctttataa gctgctttat agatagctag acatatagct ggtataccaa acatcattac
     2641 tacaaaaaaa actgataaaa acagtccagc ctgaggatct ccgttgataa agcgtgtcat
     2701 ctctcctctg aaaacttcct tgctaggaga tgtatagctt cctaaatcgt aataaatata
     2761 cgtattcaac acatggtgca gtccaaaggg gatcagcaaa cgattcaaaa acataaatat
     2821 ccccacacct aatgctccca tatcaacgag cagttttgca aaattatcaa tcccaatttg
     2881 gatgagcggc cagataaagc ccaaaaaaac agctgcgatt gtttgtagaa tcatcaccat
     2941 agtcaatggg aatttttcgc ccgcaaaata agaaaaaact actggtaatt tttgttcttt
     3001 aaagcgatta tacgtccatg ccgctactaa accggaaata attccaccaa aaatccccat
     3061 attcacttct gggtccataa tttctaagcc ttttttcaag gtagcaatcg ctaaaaaacc
     3121 agtaagtgca ggtattcctt tgtccttatt tttgacaaaa ccgattgcaa ctcctatagc
     3181 aaataagata tccaagtttc caaaaacggc atttccagct gcaccaatta ctgggatgtt
     3241 cagcatatcg tcagctgata aacgcatgat caatcccgct aatggcatcg ctgcaactgg
     3301 aagtagcatc gctcttccaa gcttctgcac atttgattta acattcattt ttattcctcc
     3361 tctattaaat atcctcatat gttactaact caatcaaagg atcatttttc actttttgag
     3421 caaatgctga atgaattaaa aattcgactt ggtgggtacg aggatacaca aaacttgaac
     3481 catttaacaa ttcctgatcc aaatacgctg cgtgacacat gacttcgatc gttttatctt
     3541 ctctcaatat catgagtaaa cttgccaaat attcttccac actcgtattg atttgtcgtt
     3601 ttttttcatc agtttctcct acgacatcga aacaaggctc aaaataatcg acatgacgaa
     3661 cttcatcttt tcgttcaaag ttgctccgaa ccggcaaatc atattttttt gctaatgtaa
     3721 caactacctc ctgattttca tccaaagtat gagtatgatg atgactgtct aaatgagttg
     3781 gtatgatccc cgcatgataa attttttgaa tctgagcatt ccattcctga tacagttgat
     3841 ctttgtcaat gttaaatgga tgctgataat aagataagga tctgaactct ccgctttcga
     3901 taagagtatc gacagttttg aggagtggtt tgccacacgt caatgttaaa tggactccta
     3961 cacctagcct aggcatttcc tttcttagtt tcacagcatg ctcgaaaccc ggcatatttg
     4021 ccatcaatgt agttgatgtc aaaattcctc gctgataagc atccataatc ccataattca
     4081 caccatggct atagccaaaa tcatccgaat taaaaatcac ttttcccatt tcattctcct
     4141 tcttttttct actaaaatag gcgcaaccaa ataatcatag tccatttact atgtgtcatt
     4201 tggttgcgcc tatagatagt tacgccctta ttttaataga ttcttgctag atgaattgcc
     4261 aaatagatga tttcattttc ttgaatggca agttgaaatt gctgttcgat gatatcttta
     4321 atctttagtg ctgtacaata cgctttgcta tgtttaaatg tttcagtaaa aaaaccaata
     4381 ttttctactg gcgtttcttc ctgataaatc aagcgtttaa ccaggaattt gatatgaacc
     4441 attaagcgat gataagtcag tgattcttta tcataaacgt ttgaatagga tttttctaga
     4501 tgggacaaaa tcgtggtcgt catttctact atttttaagc tctttaaact attaggctct
     4561 cctagctcag cattaatgat atgcatagtg atgaatccta cttcatttga ccctaactcg
     4621 gtttgatatc gatgattgat tcgctcgacc acttctactg ctatatcata ttcatttgga
     4681 taaaggaatc tcatttctgg caacataatt gctgtgacat ctctatcttc tctttttcgt
     4741 tgaatagcaa aataaatatg atctgtcaat gtaatataga tatttgaatc taatggagag
     4801 gagatcctag ctgttatcag ttcaatcact tcttccgcaa aatccataaa ttcgattgga
     4861 atctgcgaga ctatctcact gaatcgtttg atcttttctt tagaatctaa tacaaataat
     4921 ttgtcagcat cctcaacatc aaatggctta ctcactttag cagaaaagcc aatccctttc
     4981 cccatcgcaa ttttttctat tccatcgtca tcgatcaata cagcattatg attcagcttt
     5041 ttcatcacat acaccgttaa ttcacctcct ctatatgata aaacaaaaca acttgcagac
     5101 tccttcatac atatttttgt ctccaaacaa tttttaaaga caaaaaacga cctaagaaag
     5161 aaccctttct taggtcgtgc ctaattgaat agtagcaccc tacataattt acaaaaatag
     5221 tttaacacat aataaaagcg ttatcaatat cttttttact cgttttatga taatacttgt
     5281 atcgaattga tttggaggta attacataaa aacaaaaaaa atatagcaac tctctataag
     5341 aaagttgcta tattgataat tataccggcg gccggggtcg aaccggcacg tcctcaacgg
     5401 acactggatt ttgagtccag cgcgtctgcc aattccgcca cgccggcaaa tttaaaaata
     5461 ataactgggg tagctggatt cgaaccaacg catgagggag tcaaagtccc ttgccttacc
     5521 gcttggctat accccaagaa taaagggcga atgatgggaa tcgaacccac gaatgccgga
     5581 gccacaatcc ggtgcgttaa ccacttcgcc acattcgcca tcataaaaga tgttatttaa
     5641 tttctcaata aaaaactaag atgaagacat cttagtcaat accggcggcc ggggtcgaac
     5701 cggcacgccc tcaacgggca ctggattttg agtccagcgc gtctgccaat tccgccacgc
     5761 cggcaagttg atttattagt actaaggcgg taaccggatt tgaaccggtg atgaaggttt
     5821 tgcagacctc tgccttacca cttggctata ccgccattat actattatca atctataaaa
     5881 taaagaataa attatag
//
LOCUS       DACCVZ010000129         5875 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.132, whole genome shotgun sequence.
ACCESSION   DACCVZ010000129 DACCVZ010000000
VERSION     DACCVZ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5875
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.132"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            642..1376
                     /locus_tag="IVW63_002711"
     CDS             642..1376
                     /locus_tag="IVW63_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP7860935.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1392..2561
                     /locus_tag="IVW63_002712"
     CDS             1392..2561
                     /locus_tag="IVW63_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP7860936.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2577..3572
                     /gene="lacD"
                     /locus_tag="IVW63_002713"
     CDS             2577..3572
                     /gene="lacD"
                     /locus_tag="IVW63_002713"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAP7860937.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3651..4577
                     /locus_tag="IVW63_002714"
     CDS             3651..4577
                     /locus_tag="IVW63_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HAP7860938.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4596..5846
                     /locus_tag="IVW63_002715"
     CDS             4596..5846
                     /locus_tag="IVW63_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7860939.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         1967 a          955 c         1203 g         1750 t
ORIGIN      
        1 agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt gactaaacga
       61 agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat tcagataaac
      121 tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc ttaagagaga
      181 acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat ttattctcat
      241 agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga tttgaaacca
      301 aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca ctggtaagta
      361 gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta aaaaaagata
      421 ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa aagttggaaa
      481 attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat attaacaaga
      541 ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa ataccactac
      601 tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat acctttcaat
      661 caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa aacagtatgg
      721 tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc gttagtcgca
      781 cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat cgacaacatg
      841 gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct ggcgcatata
      901 gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata ttggccttca
      961 agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta ggtgagcctt
     1021 tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc gagaaatcct
     1081 atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg aaacctttat
     1141 ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag gaattttatg
     1201 ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga tcaccagtgc
     1261 tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt acattaagtg
     1321 tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact aactgaattg
     1381 gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga gcagaaaata
     1441 ctacccgaga aattcgacag caaccggaac tgtggcatga gacgtttgac cgttatcaag
     1501 aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct ggagagcgac
     1561 caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat acactaattc
     1621 cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt ggttcgaccg
     1681 atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc ttggtctcat
     1741 ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc aatcagctgg
     1801 tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg gctacacaaa
     1861 tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat gacgctggtt
     1921 ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt tttgatcaag
     1981 caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga gaagaagtca
     2041 tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc atcatttact
     2101 taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt ctcgagttaa
     2161 ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat ggtcccaaat
     2221 cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca tatacgcaga
     2281 aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa cgcgttgttg
     2341 gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt gcagattcgt
     2401 tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg atcgcattac
     2461 tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga acagtcaatc
     2521 gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg tgaagcatgt
     2581 tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca gaaggcatta
     2641 ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg gctttaggga
     2701 tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa gaattgactc
     2761 cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca cagaagcgtg
     2821 cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa accgtacccg
     2881 gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag ttaggtgcgg
     2941 atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc aatcggcaaa
     3001 agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg ccattttatt
     3061 tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc tatgccaaag
     3121 caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag tataaagtag
     3181 atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat gcaacagggg
     3241 agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc gatgcaacag
     3301 atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg gagacattgc
     3361 gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga gcaacttgga
     3421 aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa tggctgacag
     3481 aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact gccatcccat
     3541 ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt agtgataaga
     3601 gatatgtgtg attataattt atcattattg aaactgggag gatattttat atgaataaaa
     3661 gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa ttaaagcagg
     3721 caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt agctgtcctt
     3781 acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct gatttaattt
     3841 tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta actctaaaag
     3901 agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta aatttagaac
     3961 ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt ggtagaatcg
     4021 tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt tgtttaactg
     4081 gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca ttatccaaat
     4141 caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt gatgaaccaa
     4201 ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt ttattagttc
     4261 ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc gttgattata
     4321 taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta acggctaatg
     4381 gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta gcatcaaaag
     4441 catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt cttccagaaa
     4501 atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt atgttaggaa
     4561 aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt caaaaaatag
     4621 ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg gctgcagtta
     4681 tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg atagaaggat
     4741 ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca tcagattcaa
     4801 catttggtat tattggatta gctgttacct actctttggg acacaatcta gcaaagactt
     4861 atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt ttacttacac
     4921 ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt acctcgggtc
     4981 tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg tttgtactta
     5041 aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga gctttcgttg
     5101 ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta atttgttata
     5161 aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa ccactatctt
     5221 tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt ttcttttgga
     5281 tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta ttattgcaaa
     5341 actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac attataactt
     5401 atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt gcacttgcca
     5461 ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag ttatcaatcg
     5521 ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact atattaaata
     5581 taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt acttattttt
     5641 caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg acaactccac
     5701 cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg attcaagtaa
     5761 taacaattgc aataaatgtt ttgatatact atccattctt taaattagat gataatgcca
     5821 agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt agtta
//
LOCUS       DACCVZ010000130         5779 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.133, whole genome shotgun sequence.
ACCESSION   DACCVZ010000130 DACCVZ010000000
VERSION     DACCVZ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.133"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..813
                     /locus_tag="IVW63_002716"
     CDS             <1..813
                     /locus_tag="IVW63_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HAP7860940.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVHATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="IVW63_002717"
     CDS             807..1229
                     /locus_tag="IVW63_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860941.1"
                     /translation="MVNKLIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2363..3331
                     /locus_tag="IVW63_002718"
     CDS             2363..3331
                     /locus_tag="IVW63_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP7860942.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIISRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     NFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIQKRYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKEPTSLQEKIKEQKRKLELL
                     QQLAELERKQNTPSKKINKQIADNNSDITPEFKENLLDNLQNLFKE"
     gene            3341..3829
                     /locus_tag="IVW63_002719"
     CDS             3341..3829
                     /locus_tag="IVW63_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAP7860943.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNITYLKKE
                     AVTTITKVLSGNESGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQIALETQ
                     QKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQNKEKKWWQF
                     WQ"
     gene            4125..4406
                     /locus_tag="IVW63_002720"
     CDS             4125..4406
                     /locus_tag="IVW63_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860944.1"
                     /translation="MDILVRNIDPKVISEIDRRCQELTTKTGKKWSRNAYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNDYVHTNNQLIETLIGGI"
     gene            4408..4824
                     /locus_tag="IVW63_002721"
     CDS             4408..4824
                     /locus_tag="IVW63_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860945.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPNTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSRNFDPTNFLKR"
     gene            5438..>5779
                     /locus_tag="IVW63_002722"
     CDS             5438..>5779
                     /locus_tag="IVW63_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HAP7860946.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2157 a          982 c          941 g         1699 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcctttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tctctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgtgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acatgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaagtagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaact cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctcgaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaagc
     1441 cctttagtgt gttttgtaga aagggacctt atagtcactt tcacattaca aacgatacgt
     1501 cctatggacg tatcaaaagg gtgggactta tgagcaaatt aaagcaaaat ttggctagca
     1561 atccttctaa aaaatacacc tattgatcag agtcaaaata aatcagtttt cgagtgagcg
     1621 aatccaaatt tgcaactctg aagctttgca aatgagtgtg ccggcttccg taaaagtcta
     1681 ggtaacatta gtcgatatat acatagggct ctaatttgcg ttttaaggcg ttttaaacgt
     1741 tctggtatgt aattatacca aagcgacttt aaaacgcctt aaaacgaatt ttagaggttc
     1801 tgtagaacgt tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg ctttaaaaac
     1861 aagataaggg attttatcta gacttgtctt aaaacgccgt agatgagcgc tcagagcttc
     1921 taaaaggact ccttacgaac tgtttttaag caaaggagcc tttaggcgac tgcgcagttt
     1981 aatgtgagag cgtagcgatc acacctttaa agcgaccgta gggagcagat tcccagttta
     2041 ggaaatttcg cgaacctgtt tggagaaaaa aagtaggaaa attttaggcg ggaaattttg
     2101 cccccctctt ttataatctc ttttataacc tctttttaaa cctctttacc gtcggctgta
     2161 tccttactct cccaaggtgt gcagaatctt ttaggggtct ttttgtctgt ttttaggggt
     2221 ctttttgtct gtttttaggg gtctttttgt ctgtttttag gggtcttttt gtctgttttt
     2281 aggggtcttt aattaggggg ttgaccccca ttagaaagct ctttataatt ttgttaagta
     2341 gttaatcttg aaggaggatt ttatggcaaa tgaaattgtg aaataccacc atgaattaaa
     2401 tacgattcct ttacgcaaat ttacgtcagt agaaatgaat ttattcttct ctataatatc
     2461 tagaatgcgt gatgtaggcg ataaaaaagt acaatttaca ttcgaacaat taaaagattt
     2521 aagcaattat aaagcaactg caaatgttcg attcatagat gatttagaaa caacgtatga
     2581 caaattaatg gatttacgtt ttggtagaag aagtgctgac ggtttgcaac gtgaacgatt
     2641 tgttttattt aatcaattta aaatcgatgg aaaagctgat attccttttg ctgaaataca
     2701 agtccatgag aaagccttac ccttacttaa taatcttgaa gaatgggttc gatattctct
     2761 ccaacaattc aatgaattag aaagcagtta ttccaaaacc atgtttagat tattaaaaca
     2821 atacagaacc aaaggaattg ccaatttttc aaaagaagac tttcatgaat tacttgatat
     2881 ccctaaaagt tatagagaaa gtgatataaa taaaaaaatt ataaagccta ttcgccaaga
     2941 actaaccgca atcttcaaag gtttgacaat ccaaaagaga tacggaaaag gacggggaaa
     3001 gcctgtcatt ggctatcaat ttacatttaa acctgagata aaaaaatcag acgactttaa
     3061 caaacatgct ccaaccaaag aagaacaaaa taaagctttg gaactagcta atcaacaggt
     3121 tcaatctgaa aaagaaccta cttcattaca agaaaaaatc aaagaacaaa aacgaaaatt
     3181 agaactttta caacagttag cagaattaga aagaaaacaa aataccccaa gtaagaaaat
     3241 taacaaacaa atagcagata acaattccga tattacccca gaatttaaag aaaacttact
     3301 agataatctc caaaacttat ttaaagaata aggggttttt atgacagata aaactatcaa
     3361 agaattagca gatattctag gtgtttcaaa agataaagtg aagtatcaac tgaggaaatt
     3421 acctagtaat tttacctaca aaaaaggaaa tattacctac ctgaaaaaag aagcagtaac
     3481 aacaattaca aaggttttat caggtaatga atcgggtaac ttacctagtg aattacccga
     3541 ttcattacct accgattacc tactcaagga gattgaaact aagaataatc atattgaaga
     3601 aaaagatagg caaattgaaa aacttcaaat agctttagaa acgcagcaaa aattactcga
     3661 ccagcaacaa caactcaccc tacaagccaa tcaacaaatc aaaaaacttc acgaacaact
     3721 ccagctaacc tatgcagaag aatcttcaga aaaagaaccc ctttctgtta ctgaagaaac
     3781 tcaaaaagga caaaacaagg agaaaaaatg gtggcaattc tggcaataac ccaacaattt
     3841 ttatgaataa aaattgttgg gttactttct ttttttgctt ttacaagcat agcgacatga
     3901 tctcacgtcg ctatttttta aagagcataa ggaaacgcgg tatcactttc ttacgaaagg
     3961 tgctaggtag gctgtgccta ccacgtttct aagaaaaaaa tttgctatca ctttttcgtc
     4021 attgtggata gcttatgtat agtgtttcgg caaaaaacag ctatacaaat actatatttg
     4081 tatgatatac ataaattata cacaaatgcg aaaggaattc ttctatggac attttagttc
     4141 ggaatattga tccaaaagtt atttcagaaa tagatagacg ttgccaagaa ctcacaacaa
     4201 aaactggcaa aaaatggagc cgtaatgcgt acctaaaagt tctaatcgaa aacgattttg
     4261 accaggcact taggcattac aaaaaagatc aattcgattt attactcgaa aaatttatcg
     4321 atatacaagc aaaaaatact gaaacattga acgactatgt tcatacaaac aaccaactca
     4381 ttgaaacact tatcggagga atataacatg agaaaaactt ctgttcaaaa acacgttacc
     4441 ctttatccca gtcacattga cgttttagat tccatcatcg aaaaaaatcc agatatcaat
     4501 aactactcgg aagccattcg ttttctatgt atgagttatg aacctaatac taatacgaca
     4561 actaccagca accaagcaaa actaaatgcg atgggaaaag aaatttctat tatgtccgaa
     4621 atcattgcag aatttgctga tttatatcta aaagatactg gtgttcttat cggtacaaat
     4681 tctaaagtat atcaagaagt gaaagaaaaa attgaaaatc aactcaatcc ctcccgacga
     4741 aatcaaccca aaaatcgtca aaaagaaacc aatcaaacat tcacttctag aaattttgac
     4801 ccaacaaact ttctaaaaag atgaaaaaga aaccgaaaat tttttctatt tctcagtttc
     4861 ttttttaggg ggcagtcttc cagcaagatt tgcaagttac cggtaacttg cacaaaaaaa
     4921 gaaaaatccg cttgtgcgaa tccttctttt tgcattttgg ggcgctgccc caatctccaa
     4981 atatcggtta tttaatagcg tggtaactca aaaaaataga acgtactctg aaataaaaaa
     5041 agactgctct aacgagcagc caataaaaaa taatgagcgt ttattcttga aaaagcagcg
     5101 cgcttatgaa gcgctgccaa aaatttacca tattttatga aaaataacaa gtttctaaaa
     5161 aggaatcggt taagattcac aaagaatcgt aaacagacaa tagcggaaaa tcaagcttcc
     5221 gaacgtacct tttagctaga ccaatgaaaa atcacaaagt gagcccctgt atcggttgat
     5281 acaagggcta cttggcatac tatacattat gttaactaac gctataaata acgattatgt
     5341 tcccaaaaca atattttatg aactataaca aaaatttgtt atcgcatatt gtatatttta
     5401 attataggtg tataccactt aaatttaaca caaaggcgtg attattttga aacccaaaaa
     5461 gaaaatttat ctaggtctcc tcttttcctt gatgattgga atttttagta taggaattac
     5521 aaatacctat gcttcagaaa attctaattt caatatcaac tcccaaccaa ttgaagaaca
     5581 agcaattaat tttgcgaaaa ctgattttga acactccata acttcaattc ttttaatgga
     5641 aaataacacc gaaactgata ttaactatac tcttggttcg ccatttaaaa tgctcgatgg
     5701 agaaaatacg gcaaatagtt ctattttctt tccagtattt tcagacgctg ataatacgat
     5761 taaatatatt tataccgtc
//
LOCUS       DACCVZ010000131         5677 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.134, whole genome shotgun sequence.
ACCESSION   DACCVZ010000131 DACCVZ010000000
VERSION     DACCVZ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.134"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(240..606)
                     /gene="ssrA"
                     /locus_tag="IVW63_002723"
     tmRNA           complement(240..606)
                     /gene="ssrA"
                     /locus_tag="IVW63_002723"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(777..1550)
                     /locus_tag="IVW63_002724"
     CDS             complement(777..1550)
                     /locus_tag="IVW63_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP7860947.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1694..2044
                     /locus_tag="IVW63_002725"
     CDS             1694..2044
                     /locus_tag="IVW63_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAP7860948.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2025..2741
                     /locus_tag="IVW63_002726"
     CDS             2025..2741
                     /locus_tag="IVW63_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7860949.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2741..4189
                     /locus_tag="IVW63_002727"
     CDS             2741..4189
                     /locus_tag="IVW63_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7860950.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4260..4769)
                     /locus_tag="IVW63_002728"
     CDS             complement(4260..4769)
                     /locus_tag="IVW63_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860951.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4759..5484)
                     /locus_tag="IVW63_002729"
     CDS             complement(4759..5484)
                     /locus_tag="IVW63_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860952.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         1936 a          984 c         1120 g         1637 t
ORIGIN      
        1 gtttttcctt ccatcaacat aatgttcacc tcaaaaagag tatacgaact aatgttcttt
       61 ttgtaaagta ggaatatcat tgataatatg gatggaacat atatattaaa aagtgttctt
      121 tttgaatgct attttgaatg ccattttcat tcatttaacg aaaatctgcg aaaataaaaa
      181 atgctcaaac ccttataaaa taaggattta agcatctagc gaaatctgct gaaatctcac
      241 aatggagacg gcgggagtcg aacccgcgtc caaacacatc gccacttaaa aatctacgtt
      301 catagtcaac tcatttaagg attcacttta cagcttgccg agtgacaggc attctgtatc
      361 gctagtctga tgttctcttt ttcaacttac agacggaaag ttgaaacgta tcccactaaa
      421 gttaggaccc ttactcgagc acatgggcga tgccgagagg atctacgcta actgttttta
      481 ggcagctaaa gcgtaagagt tgttttcgtt tttagcagtt atatttaact gtaacgtttt
      541 tacgtagacg taacctacga aacgcaattc aagctcgact gtgcctgtcg aatccgtaac
      601 gtccccgtta gctaacaagg gttacgtgta tttttcatac aaaattagta tagcatatat
      661 tgggataaat tcaataaaaa agcgaatcat atcccattat ttatataata actgcccctt
      721 tcttaagaaa aaataagcga ttttcttaag aaaagaggta gcttcaaaaa aagatcttaa
      781 atcagatcaa aatacttcaa tgcgtggaca attccgcctt ctgtattttt ctttgtgata
      841 aaggtagaaa gttcttttaa tccgtcatag gcgttgccca tagcgatttt gttgtcgcaa
      901 gcttccaaca aggcaaaatc attcggacca tcgccaaatc caaaagtagg aactttttcc
      961 agctgaagtt ctttttgcag acgtttgaca cctgcccctt ttgagattcc tttcttcact
     1021 gtatcgatcg agtaaggacc attccgataa aaagttagct caggaaaatg ttcgtgatag
     1081 tattcgtcac ctgattgaga taagatcagc aacatattta ctgtgttttc tttaaagcct
     1141 aaaggatcaa tttccggaac atctgaatga atgaagtcgt aagcattgat cattgtttgg
     1201 ctatgaccgg tacaccagat tttctgatcg ttatagtaag aaagttcatg accgttcaac
     1261 tgtacatgat catacatttt ttgacattct tctgaagaaa atgtttgaga atagatttct
     1321 tcgccgtcta ctcgaatgaa agaaccattc atggtgaccg cagaagtaat gcccgcatct
     1381 tccatgatag agtggatttc tgcttctgta cgtcctgtag cgatgacggg gagaacattg
     1441 ttttctttta atgcgttcat agcttttgcc acttcgggtg tgatttttga tttcgcatct
     1501 agtaatgttc catcaagatc aaagaaagtg attgcacgat aatttgacac aaataaaact
     1561 ccttttttat tggaataagt ttatcttaac aaagaatgaa caaaagacaa acctttcgtg
     1621 aagaattcct gaacatattg gttcagtcaa caatttagag tatactataa gaagagaatt
     1681 taggagggaa agaatgattt ttttcagtat tggtatctta ttcttaataa ttggcagtct
     1741 ttttcggatt ctgccctcaa aaggaaatct gcctttttat gggtatcatt cgcctcttgc
     1801 cgcaaaaaca gacgctcatt ggcggctggc tcaaaagaca agcggaaact ggttttttct
     1861 tatgggctta ctgatggcat tgatcggcta ttatttaaag acatctgggc atacgaatta
     1921 ttttctgatt gaaatgcttc tgctagtatt tccaattatg cctattttta ttatgacaga
     1981 aaagaaatta cagaaatatg acctggaaac tggagggaac gataatgaat attttaatga
     2041 ttgaagataa tcaatctgtt tctgaaatga tgcagatgtt tttcttaaat gaaggttggg
     2101 aagcaacttt caagtatgat ggaaaagaag ggctcgatgc ctttttagaa aacccacaac
     2161 attgggatat gattacacta gacctgaatt tgcccacact ggacggtatg ctagtaggaa
     2221 gagagatccg caaagtttca agtactgtgc cgattatcat gctgacagct agagattctg
     2281 aaagcgatca ggtgatcggc ttagagatgg gggcagatga ttatgtcaca aaacctttca
     2341 gtcctctgac gcttattgct cgaatgaaag ctttgcatcg ccgtagtgag ttggcagaag
     2401 caagagaaga agcagtagtt tcagatgatc attttgatat cgagactagt catttcaaga
     2461 tgaatacgaa aacacgagaa gcgtatctgg acaaccggcc aattgaagga ctgacgccta
     2521 aagagttcga tctattgttt actttagcaa aaaaaccacg tcaagtattc tctcgggagc
     2581 agttgcttga attagtctgg gattatcagt actttggtga tgaacggaca gtggacgccc
     2641 atatcaagaa attacgacaa aaaatcgaaa aggtcggacc acaagtcatc caaactgttt
     2701 ggggagtcgg ctacaaattc gatgattctg gtgttgccta atgcgttatt tgtatcagca
     2761 actcttagct ttctgcggaa tggtcgcgtt gatcttattg atcgttggag tttcttttac
     2821 acaactgaca aaacaaacga ttgaagaaaa caattaccag caactgtttg gatatgctga
     2881 atcagttgaa aagacaacgc aaacctatgc cgatacgctc ccgcagttta gtcaagatca
     2941 ggcgtttcaa aatgcattgc tgctgacaga gcaagtactg acagaacaaa atgtgaactt
     3001 tatatttatc gataaaaacg aacgtgtcat ttatccgact aatacagctt tactgaattt
     3061 taccttaaca gctgatcaat ggaaaaatct gaggaatgga cgtcaagaaa aattcacatc
     3121 gaataaaaat attttaggac aagcacaggc gacctcttac gcacttgtgc catttaattt
     3181 gaatcatgaa ttctatggag cacttgtagt tagtcaacct gcgcgaaata tcgataacag
     3241 cgttcgtcca attacactga acctgttcaa aggatttatt ttttccagta tcgttgcagt
     3301 tattgccagc tatgcttttg cagcattcca agttaagcgt atcaatcggt taaggaatgc
     3361 gacgaaagaa gtgacgaatg gtaattttga tgtacagctc cccgtacatg acaaagatga
     3421 atttgatgag ttagcagatg atttcaataa aatgacgaat tcattgaaag aatctcaagc
     3481 agaaattgaa gaacaagaaa atcgtcgaag acaatttatg gcagatgctt ctcacgagat
     3541 gagaacacct cttacgacaa tcaacggact tctggaaggg ttagaataca atgcaatccc
     3601 tgaaaatcag cgagaaaacg cgattaaatt gatgaaaaat gaaacagagc gtctgatccg
     3661 tttggtgaat gaaaacttgg attatgaaaa aatccgtacg aatcaaatca gtatggtcat
     3721 taaaaaattc aatggaacag aaacattgaa aaatattgtt gcacagttag aagctaaagc
     3781 agaagcagca ggagatacat tgacattgaa agccgttgat gatattgatg tttacgctga
     3841 ttatgaccga tttgtccaaa tcatggtcaa tattattcaa aacgcgatac agtttactga
     3901 aaacggccaa atcacgatta ctttagaaaa aggctatctt gaaacgatca tcacgattga
     3961 agatacggga attggaatgt ctgaacaaca aatgaaaagt atctgggatc gttattataa
     4021 agtagatcct tcaagaaaaa atacaaaata tggtgaatca ggattaggtt taccaatcgt
     4081 gcagcaactt gtacgcttgc ataaaggaaa attagaagta gaaagcgaac taggaaaagg
     4141 aacaaaattc gctgttcgtt tgcctgacgt agaaatcaaa aaagagtaaa aaacaagcgg
     4201 tataaaagat catgaatcga tcttctatac cgcttgtttt ttactataaa atgattgatt
     4261 tagcccgcgg gctctaaacg atcaatataa ggactttgag caatagtagc atcatgagta
     4321 aagagtaaga taccttgatt ttcttcatga gctaaataag aaagcaagtg gagtagctct
     4381 tggatctcca atacactaag ttcatcaaat gtatcttcaa taacaatatt gtttcgcttg
     4441 gaaagcaagg catgaagtaa ttgcagcttt actttttcaa aagacgtcaa ctcagctgcc
     4501 gcacaattaa gcaaggaagg agagatatca agtttttctt gataggccaa acgatcttgt
     4561 ttgatttctt tttccggtac atccaacagg acatggtctt taagattcag ataaggaaac
     4621 atcggccaat ttttttggat gatcgcaaaa ttatccagtt ttgcaacaag aacctctttt
     4681 ttcaagtgct ccaatatttt atgctgtttt tcgagaggac acaaaataac ggtcaagtgt
     4741 tcagcatgaa tcaaatattc aggtttcatt acgtccaggc ctcctacttt gcaaatgatg
     4801 gataaaaaaa gtgaaaggga atagactaag aatgagacag catccactga gcccaataag
     4861 agtttgggca aatcccttaa gtatatctgt gaaaaaaaga tcattttgga aatcgatggt
     4921 aaaaaaagtc tgttgatcca tcggaattgt aagtccgctt accgaagtca agatatcacg
     4981 gatatctggc agttcagtag tctttaagac aagaaaattg atcctttgaa gaagcgcttc
     5041 ataaactgac tggaagctta cgatccacaa taaaaccaag atacaacaaa gaaagagagg
     5101 aaagaacagc tgccagaaaa taaaaaggaa taatttggtt ttagaaagac cagtcaggtg
     5161 ccaattgatc aattcctgct tgttttgcct gactgaatag taaaagaaaa agataaaaag
     5221 gaaggcaaat agaaaaaata aactgaatat gccttttata taaaatcggc tagctaattc
     5281 taaagccgga agaagctctg tagatgcaga agcgccaata aatgaaagcc gatcttggac
     5341 ttgattggct aaagccgatt gcaaatggta aagagtcagg catgctatca ataaaaaagc
     5401 agaaaagctt gaaaataaac aatagagtat tgtctgcttt ttgtaataaa ttaatcgagc
     5461 agtagcatag cggattattt tcatactttt cacctctata aaaagtatag aaaatgaata
     5521 tgaataaagt atgaaattcc tttagtgaaa tcacgaatta aaaccagaaa atattttgta
     5581 aaaagcaaga ggttgtgaag aagctgccct attctattac cgtagatgca agcttttgaa
     5641 cactgtttat tcgaaaagag gagcagcgac aataatt
//
LOCUS       DACCVZ010000132         5592 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.135, whole genome shotgun sequence.
ACCESSION   DACCVZ010000132 DACCVZ010000000
VERSION     DACCVZ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.135"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..227
                     /locus_tag="IVW63_002730"
     CDS             <1..227
                     /locus_tag="IVW63_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HAP7860953.1"
                     /translation="KTTEFDILHALMSTPNKVFSRSDLIEKVKGIEFDGLDRSIDSHI
                     KNLRHKIENDAKSPMYILTVHGTGYRFGGH"
     gene            227..574
                     /locus_tag="IVW63_002731"
     CDS             227..574
                     /locus_tag="IVW63_002731"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860954.1"
                     /translation="MRKRTIKTQLAVSFLAIATLIIGSISLVALSLMNNHFSKYVEER
                     QEDLLNQYVYTIDLLWLNSGETWNSEELAALSEKVLENNIYFSIEDEQGNMVWELTGK
                     DLKSAQEKLKKMH"
     gene            571..1620
                     /locus_tag="IVW63_002732"
     CDS             571..1620
                     /locus_tag="IVW63_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7860955.1"
                     /translation="MKVSEKNSVKLDETIEVKKKLINDGNEFGKVTFYYFGPFAYTEH
                     DALFISSMKQSLMYVAIAALLVSFILASWISARLGLPLKHVSDFTHKLTRGEYADKIP
                     QETSIIEINSLIDSLNDLSNQLEKQHGLRKRLTTDISHELRTPLATLKGNVEGMIDGV
                     WKITPERLQSCYDEIDRLTRLIGNIEIINKIEAKYDHLNKTEFNIYKLIESVIENFAS
                     KIESKNLHVEIQGDNINISADKDKMNQVVINLLNNAIKFTQKEGTIKFSISKNKDHVL
                     LIVEDNGIGIEKDQQLHIFDRFYMADPSRSRALGGQGIGLAIVKSVIEAHKGSITVKS
                     KLGLGTKFVIKLPFQ"
     gene            1635..1841
                     /locus_tag="IVW63_002733"
     CDS             1635..1841
                     /locus_tag="IVW63_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860956.1"
                     /translation="MFQKQIKIAKLVCECWAKKIFFQLISIDSVEKVHLDILSNSVVI
                     FSKKDLSIATIKKEVFGLQIYEMT"
     gene            1862..2458
                     /locus_tag="IVW63_002734"
     CDS             1862..2458
                     /locus_tag="IVW63_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhK family protein"
                     /protein_id="HAP7860957.1"
                     /translation="MKTVKKMTKLVFASLGIIVFLGACSNQSESNNSNSTNEESTSTA
                     SSEMNSMEGMNHEGMVPSSMKDAANPKFPVGSNVILLGDHMEGMKGANAQVVGAFDTT
                     MYEVSYEPKTGGPMVNNHRWVVQEELKDTETVANEGDTVILNADHMDGMMGAEAKVDK
                     SITGTVYVVNYTPTDGQEEVKNHMWVTEDEMEYDENNE"
     gene            3410..4009
                     /locus_tag="IVW63_002735"
     CDS             3410..4009
                     /locus_tag="IVW63_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP7860958.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLRDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQAQDFSKYLFPSRKGADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            4058..4774
                     /locus_tag="IVW63_002736"
     CDS             4058..4774
                     /locus_tag="IVW63_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HAP7860959.1"
                     /translation="MNEEKQPNFPDKYHLSRKESVYLLKKNIVELVYNAGKFEGLNTT
                     LLQTEGIIKYNRANNVAVDDVLTVVNLKRGFEMLLNDVQEPLLETSKRINRIVAAEDA
                     LFPGEIRTGGVELSTIQGRYVPPMLTEDEVNNQYGEIMNQEISDTEKALRLFLFISKN
                     QIFWNGNVGTALLIANKIMFSNGLGLLSIPENVFMKFNELLSKYCNSNLLVNESNIIS
                     FLYEQCIFGINYLKIIQHTI"
     gene            4788..5567
                     /locus_tag="IVW63_002737"
     CDS             4788..5567
                     /locus_tag="IVW63_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HAP7860960.1"
                     /translation="MMTIDEAKQLATYFSVGSAGYILDFTNVTWNIFTKKIVGIEIQN
                     HYGGSKGVSFQKFLLDDQFDDSLKNRLIQSLKGIMDRDKKYESTEMNPIVQLLFEEVF
                     KEDTSTALRKMKFSSEIDLLYIRQLPIRIQTDIKNKDFDSVLTKANTLIDEVLKFIIE
                     NTEGPSVNINLFKSKELRKEVFGRLNIKTEKDMDNRIKALVGALNTLSDKILEMRNSQ
                     GDAHAHGSNRIVIKEEEAILVANSSMVLCEYVFTKYKGLNR"
BASE COUNT         2035 a          786 c         1084 g         1687 t
ORIGIN      
        1 ttaaaacaac tgaatttgat attctacacg ctctaatgtc cacacctaat aaagtctttt
       61 ctcgtagtga tttgatagag aaagttaagg gaatagaatt tgatggacta gataggagca
      121 tcgattctca tataaaaaac ttaagacata aaattgagaa tgatgctaaa tcacctatgt
      181 atattttgac agtccatggt acaggataca gatttggtgg ccactaatga gaaaaagaac
      241 gataaaaact caattagctg tttccttttt agcaatcgca acattaataa taggatcgat
      301 tagtttagtc gcattaagtt tgatgaacaa tcattttagt aaatacgtgg aagagcggca
      361 agaagatttg ttgaatcagt atgtatatac aattgattta ttgtggttaa atagtgggga
      421 aacatggaat agtgaagaac ttgcagcact atctgagaaa gtattagaga ataatattta
      481 tttttctata gaagacgaac aaggcaacat ggtttgggaa cttactggaa aagatttgaa
      541 gtcagcacag gagaaactga aaaaaatgca ttgaaagttt ctgagaaaaa cagtgtgaaa
      601 ctagacgaaa caatagaagt gaaaaagaag ttaattaatg atggaaacga gtttggaaaa
      661 gtaacgtttt attatttcgg accttttgct tatacagagc acgatgcctt gtttatctcc
      721 agtatgaaac aaagtttaat gtatgttgca attgcagctc ttcttgtatc attcatactt
      781 gcttcgtgga tctctgctag attaggattg ccactaaagc atgtaagcga ttttacacat
      841 aaattaactc gtggggaata tgctgataaa atcccacaag aaacttcaat tattgaaata
      901 aattccttaa ttgattccct aaatgattta agtaatcagt tggagaaaca gcatgggctt
      961 cgaaaaagat taactaccga tatttcacat gaattaagaa ctccattagc tacgcttaaa
     1021 ggcaatgtgg aaggaatgat tgacggagtc tggaaaataa ctcccgagcg cctacaatct
     1081 tgttatgacg aaatagatcg tctaactcgt ttaattggaa atatagaaat aatcaacaaa
     1141 attgaagcaa aatatgatca tttaaataaa actgagttta acatatataa gttgattgaa
     1201 tccgttattg aaaatttcgc cagcaaaatt gagtcaaaaa accttcatgt tgaaatccaa
     1261 ggggataaca tcaatatatc tgcagataaa gataaaatga accaagttgt tatcaatctt
     1321 ttgaataatg ctattaaatt tacgcaaaag gagggaacca ttaagttttc tataagtaaa
     1381 aataaagacc atgttctttt aattgttgaa gacaacggca tcggtataga aaaagatcag
     1441 caacttcata tttttgatag attttatatg gctgacccct ccagaagtag agctttaggg
     1501 gggcaaggta tcggattagc tattgtaaag agcgttattg aagcgcataa aggtagtata
     1561 actgtaaaaa gtaaattagg tctaggaact aaatttgtta taaagttacc atttcaataa
     1621 aggaggagag ttatttgttt caaaaacaga taaaaattgc taaactagta tgtgaatgtt
     1681 gggcaaaaaa aatatttttt caactgattt cgatagatag tgtcgaaaaa gttcatttag
     1741 atatcttatc aaattctgta gtaatctttt ctaagaagga cttatcaata gctacaatta
     1801 aaaaagaagt ttttggatta caaatttatg agatgaccta aatgtgatta attaaaggag
     1861 gatgaagaca gtgaaaaaga tgacaaaatt agtatttgca agtcttggaa ttattgtatt
     1921 tttaggagcg tgtagcaatc aaagtgaatc gaataattct aatagcacaa acgaggaatc
     1981 gacttctaca gcgtctagtg aaatgaatag tatggaggga atgaatcacg aaggtatggt
     2041 tccttcttca atgaaagatg ctgcgaaccc taaattcccg gtgggaagta atgttatact
     2101 gctaggcgat catatggaag ggatgaaagg tgcaaatgct caagttgtag gggcctttga
     2161 tactacaatg tatgaagtaa gctatgagcc aaaaactggg ggaccaatgg ttaacaatca
     2221 tcgatgggta gtacaagaag agttaaaaga tactgagact gtagcaaatg agggcgatac
     2281 tgttatcttg aatgccgatc acatggatgg gatgatggga gctgaagcaa aagtagataa
     2341 atctattaca ggaactgttt acgttgttaa ttacactcca accgatggtc aagaagaagt
     2401 taagaatcat atgtgggtaa ctgaagatga gatggaatat gacgaaaata atgagtaatt
     2461 ttatatacta aaccaacaag ctggtacatg gtcttcgtat tctcaacatg aggaatatga
     2521 gctctttgtt aataaggact gatgagttgt gcaaaatcaa atctgggtca gaacgaacct
     2581 cattctggct cagatttttg gctcttcgac atttagtgct ggtagagaga caactgaaaa
     2641 tttagtcata accagttagg cagagtgctt aactggtttt tgttcgcatt tattattctt
     2701 ttgatattgg ctgcttgccc ttcaatttta tttggtttct taatcaactc ttcatataac
     2761 cccaaatcat atattaatga ggtgcctcct attcctataa atctatctct tctttaatag
     2821 tatgagaaaa gtctactctt gtagatttaa attgtcaaca aaaaatttac agatgtaaat
     2881 gataagttga atagagaaag ataaattatt tttttggtat tcatataagg ttaattatgt
     2941 attatcacaa aatgattgtt gtcgaataac taaaagtgtc aaaacaatga tgaaatcatt
     3001 tagttcttat aaattagaca agagaaaata aatattccat atctacttta ttggatccat
     3061 aacatgacta aattctgaat actttttaaa gcttatcatt tggtaaaact gaatataagt
     3121 taattatata gactgaaaat tttgaatttt cagaatagaa taacttaaaa gtactgacaa
     3181 attttttaaa ggggcaatat taatgttctg agataatcaa atcttaccga aaatatcaaa
     3241 agtccaatgt gacacaattg gattttgtca cattcgttaa aatcgctcca tccttagagg
     3301 ctctaatagg aaatcacttt tcttttagcg ccttttttct atagcttgtt taaatgtgac
     3361 ttattatctg ttataatcgt attaagtaac atttgagagg tgtctaaaaa tgaaaagcgt
     3421 ggaaccgatt cgcgacaaaa aaaagatcga tgccatgaag gccattttgg cttccggaaa
     3481 atatgggcaa cgaaatttgg tgcttttttc gatcgggatc aatacagcct atcgaatctc
     3541 cgatttaaga cagttaaaat taagggatgt gctagaaatt tcccgtgggc gggtgatcgt
     3601 caaagaacgt ctggccatga aggaacaaaa aacggccaaa cacaattcgg tcttcatttc
     3661 gaacaaattg cgaaaagtga ttcttgatta tgttcaatcc gaatttcctg agcagttgca
     3721 agcacaagac ttcagcaagt atttgtttcc aagtcgaaaa ggagcagata cgcctttgac
     3781 ccgacaaagc ctttggcgga tcattcatga agcaggaact gcagttgggt taaaagaaat
     3841 tggtccccat tcgatgcgta agacctttgg ctatttttta tacaagcaag gaaccaaaac
     3901 agagatcatt cagtcgctgc taaaccattc ttcacaacgg gagaccttac gctatattgg
     3961 aatcacccag gaagacaaag atactgcagt aaagagtttg gatttatgac agaataatgc
     4021 cctatataat agaaggaaaa attcaagagg tgagaaaatg aacgaagaaa agcagcctaa
     4081 ctttcctgat aaatatcact tatctcgcaa agagtctgtg tatttattga agaaaaacat
     4141 tgtagaactg gtgtataatg cggggaaatt tgaagggtta aatacaacgt tgttacaaac
     4201 agaagggatt attaagtata atcgggccaa caacgtggct gtagatgatg tcctgaccgt
     4261 cgttaactta aaaagaggct ttgaaatgct tttaaatgac gtacaggagc ccctgttaga
     4321 gacaagtaag cggattaatc ggatcgttgc agcagaggat gcgctttttc ccggtgaaat
     4381 acgaaccggt ggggtagaat tatcgacgat tcaaggaaga tatgtgccac caatgttaac
     4441 tgaagacgag gtaaacaatc aatatggtga gataatgaat caagagatat cagatacgga
     4501 aaaagccctg cgactgtttc tattcatttc gaaaaatcaa atattctgga atggtaatgt
     4561 gggtacagcc ttgttgattg cgaataagat tatgtttagc aacggtttag gactattatc
     4621 aatacccgaa aatgtattta tgaaatttaa cgaactttta tcaaagtatt gcaacagtaa
     4681 tctattagtc aatgagtcaa atattatatc atttttatat gaacagtgta tctttggtat
     4741 taattatttg aaaataatcc aacatacaat ttaagaggta taagtaaatg atgactatag
     4801 acgaagcaaa acaattagca acttattttt cagttggttc agcgggatat attttagact
     4861 ttactaatgt aacgtggaac atatttacaa agaaaatcgt agggattgaa atacaaaatc
     4921 attatggggg ctcaaaggga gtatcctttc aaaagtttct gcttgacgat caatttgatg
     4981 attcgttaaa gaatcggtta atccaatctt taaaaggtat tatggatcga gataaaaaat
     5041 atgaatctac tgaaatgaat cccatagttc agttgctttt tgaggaagta tttaaagaag
     5101 atacttcaac tgcattaaga aaaatgaaat tttcaagcga gattgattta ctttatattc
     5161 ggcagctacc cattaggatt caaacagata ttaaaaacaa ggattttgac tctgttttga
     5221 caaaagcaaa tactttaata gatgaagttc taaaatttat tattgaaaat accgaaggac
     5281 cgagtgttaa tattaattta tttaagtcaa aagaattaag aaaagaagta tttggccgcc
     5341 tcaatattaa aactgaaaaa gatatggata atagaatcaa agcccttgtt ggagcactca
     5401 atacattatc agataaaata ctcgaaatga gaaatagtca aggagatgct catgcacatg
     5461 gctcaaatag aatagtaatt aaggaagaag aagcaattct tgttgcaaat tcttctatgg
     5521 ttttgtgcga gtatgtgttt actaagtata aaggattaaa tagataataa aatgcatatt
     5581 ttatagtata ca
//
LOCUS       DACCVZ010000133         5585 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.137, whole genome shotgun sequence.
ACCESSION   DACCVZ010000133 DACCVZ010000000
VERSION     DACCVZ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5585
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.137"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(1016..1306)
                     /locus_tag="IVW63_002738"
     CDS             complement(1016..1306)
                     /locus_tag="IVW63_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860961.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1648..1944
                     /locus_tag="IVW63_002739"
     CDS             1648..1944
                     /locus_tag="IVW63_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860962.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1951..3903
                     /locus_tag="IVW63_002740"
     CDS             1951..3903
                     /locus_tag="IVW63_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAP7860963.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3975..4472)
                     /gene="dfrG"
                     /locus_tag="IVW63_002741"
     CDS             complement(3975..4472)
                     /gene="dfrG"
                     /locus_tag="IVW63_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAP7860964.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4799..5491)
                     /locus_tag="IVW63_002742"
     CDS             complement(4799..5491)
                     /locus_tag="IVW63_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAP7860965.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         1819 a          972 c          903 g         1891 t
ORIGIN      
        1 acatacttgc aaagtaatac tacaattcct aacataatcg tagaatttaa taatttccat
       61 agcataaagt gtttagaaaa gaacattaag aatagttcta taataattct tgaactccat
      121 gtcttataat gttctatcga agcacccaaa tagccaagtt catctaatct acttgcataa
      181 actacgtcat ccgctctcat agtcggcata tacatattaa agagtaaaaa gataccccaa
      241 atccctatta gtaacaagat cagttctttg ttattcgtta tttttctatt atgtttgttc
      301 atttttatac tccttcttat atttcctaat agagtataac atagctttaa gcattactta
      361 aagataactt aaaagttatc ttttaaatac ttaattgtta aataccttat ttgatgcaaa
      421 agaaatctac gatagtcaac aaaaaaattt tcattatatc cagaaaaatt tttcttagtt
      481 aaggacctat ggattgcagt aatgcagaat tcgtcgaata aactgccaaa gacatacaat
      541 catattgctt ttaaaattga cgaacaagat atagattcgt ttgtctcaaa aatccaaatg
      601 ttaggtttaa ctgtcgaacc aggacgttct cgtgtgaaag gcgaggcttc ttcaatttac
      661 ttttacgact atgataatca cctcttcgag ttacataccg gtactctcca ggaacgttta
      721 aaatcctaca attccactac ctgagactag taatgactag tctcttttta tggcctctga
      781 tccccccatt gagcgaatac taatagggct tcgaattgat ctgttcaatc tttaagcaat
      841 atccctcaaa tgagtttgga aagtttagtg attcatcaca aatacttaaa tacatgtagt
      901 tatatataga ttgaggttct tgtgagcgta tgctcgtgtg ggttcaaatc ccatcgtctg
      961 catccatctt tccaaaacaa gcggctagga catttttgtc tcagccgctt gttttctagt
     1021 ttattctttc atcttgtcgg accttttttc ttgggtatag acttttctca tattctacca
     1081 caattttggg tttccctaac acatgatagg atctcacaac aaattgcttt ctattattat
     1141 aataacctgt aacgactaac ttcatccctt cgtctacttc agctaggaag ttcaaactat
     1201 gggaagcaat caaacaattg accccattta aactgaaacg gatcaacggt ctggcactaa
     1261 cttgcaaagt acggatctta tctactgttc catatttttt ctccataacc ttcacctcaa
     1321 taccattata cgaacataca ttccctttgt aaagaagaaa ctctgtttta tctttttgac
     1381 tttttgtcta ttacctttct taaaatcata ttggcacttc ctgcgaagat gaaggacatg
     1441 tactaaaaaa aagaggcagc agtatagatt taagtagttc agttttggag tacaaaaagt
     1501 gaaaatgtaa acctaaatga gtatcaaatt gcaactgaat ttgatactcg ttttttattg
     1561 ttaaatcaac gtttgttgtt aatttacacc acaaaatgta agttaaaatg tatataaaaa
     1621 tgcgaacgtg aaataattat tgtaggaatg caaattggtg tgttaaaatg gttacaattt
     1681 actaagcaaa aaggggtgca ttttcctatg caatttcttg agccaaaaaa taagaacgct
     1741 aagtctgtgg attgggaaat atcagagcaa gtaagggtga tagttaagca atacgctgaa
     1801 tatgcagagc gtactgaaag cgaagcagtg gatgaattct tattgaacat tttagacgat
     1861 aagaagttta ttgaatggat tgccaacaag cgaagtaata agcggattgt tgaaaaaatg
     1921 ggtatcaaag atagagtggg ttgatagaca atgaccaagc ttaaaagatt agccacgaag
     1981 gaagatgaaa ttgtagatgt taaaattccg atttcaaacg aagaattaaa agatagggct
     2041 aaacaatatg atttattaac tccaaaacga tttgcaacaa ggtataacaa aatgttgttc
     2101 ttgccaacgt cttttaaatg gaacggttct gaatatccca ttcaatataa ttactgcatc
     2161 aatccgtttt gttgtaattt tgggaaagaa cagcacaaat tcaaagatgt aaaagggaaa
     2221 ccaagtcgat ataaaatgac tggtagttcc aaagataaag gtcataaagg tatgtactgc
     2281 aatgacaatc ctattggcag aggtgtatcg caaaactgta cagtaacccc tttatctaat
     2341 tggtctgttg ttgaagaaat taaacgcctt atagaaatca atagcatcca agatgttgag
     2401 ccagattatc aatttcataa agaaggctgc tcggaagaag aatcaacccc attcaatgag
     2461 ccgaagcaat tttacaaaag ggggaaaagt aggggcaaat ctcaacgcta tcaatgtaag
     2521 gcgtgtaaga agttcactaa tgttctacca aaaagagaag aaaccactac ttatcaccaa
     2581 caaaagaaca ccattcttcc aatgttcgct aagatggttg ttggaagggt ttcagtcagt
     2641 cgtacttgtg atattttagg aattggagtt ggaacctact atcataagct ggagtggctg
     2701 tataggcgtt gtttggagtt tttagaacga tatgagacac aaccccttca aacaaagaaa
     2761 tttaacgaga tgtggcttaa tacggacaag atgcactact acctaaataa cgtccgtaag
     2821 aaaggacaag gttcaaagaa atatacgggg tttgaagacc ttaatatgca aacgtatata
     2881 gttgtatctg ctgaggtctt atcaagatat gtgttccgtt ctgatgttgc ctatgattgg
     2941 aatatttcaa tggatgaatt aaatgaagat acaagaaaat tcaaagaaga ccatctcaat
     3001 acttttagtc gtaaaaatga taggttagat tggtcttatt atccacaaga accatccgct
     3061 aacgatagcg aaaataggaa tgcttatctt cacgaattag ggaaaattac taataggagt
     3121 agatttgtcg atggtttaaa tgttgatgct ccttatacta caactgctca ctattggtta
     3181 attaaacaaa tggttaatgc cgacgaatgg cgaatgatta gtgatgatga cttctctatt
     3241 agaaacgcct tttatagagt attcacgaaa gaattaaggt tgagcgatgc acatcatttt
     3301 atttgccaag ttaacaagac gaaaagcaga aaacaatgct taaaagaatt cggacaagca
     3361 aaagcagaac tgctcgattg gggagatatc agaggattca aaacaaagtt tctacggact
     3421 ttggcatctc attatctaac tgaattacta acaagtcatc aattccacga agaggctatt
     3481 agtaaagatg gagaaagata tcgcaaatat gccgataacc ctatcaaaca tccattagcc
     3541 actaaggata aaggatttta ttcagttgat tgtagaacgg atttatctgc tctggaacca
     3601 aacgaaatcg caaagatgct attaaatgtt aatgaccatt cgaccaatag ctttattcaa
     3661 cagataagac gttatatatc atctcttgaa agaccattaa caacagctcg tggtgataag
     3721 aagagctata tttacgctaa cttcaatccg aagtatgctc aatttgcgat tacaattcta
     3781 agaacttact acaacttttg tcgccctttt aaatcagcgg ataaaaaggt tttgacacct
     3841 gctcaaagat tagggattac agataaacaa tttgattgga aagatataat ttatttcaaa
     3901 tgacaaaaag agcttggagt aatcccaagc tcttgtgctt tatctttact gttcttcttc
     3961 aattaacgca cccgttaact caataagttt tttctttcat atacatgaaa atagtagtta
     4021 tacggatttt tatcattctt tatccctttt tgggcaaata cctcattcca ttcctcataa
     4081 ttcacttctg gaaaaaaagt atctccttcg aattcatgat gtatttttgt gatgtacatt
     4141 ttctcaacat aagggaaaaa caaattataa atctgttctc ctccgaaaat aaaaatttct
     4201 tcttcgtttt tacataactc aaaaacatct tctattgaat gaacaatttc acaaccatta
     4261 aaggtaaacc ccttatctct cgtcagaata atatttcttc tgtcaggtaa ggctcttccg
     4321 attgattcaa ggttcttcct acctaatatt atcggatgtc cctttgtagt atttttaaca
     4381 tattcccagt ccttgggaat cctccaagga atgtcattct ctttgccaat cactctattc
     4441 ttatccatcg cagcaatcaa agaaactttc atttataaca cagccttttt aactaattta
     4501 ccatctaatt tcttatttct atcaaaaaac cttttctcat tatcctgccc gttagttgaa
     4561 taagcaattt tttctataag ttatattatc ataataccac aaaatcacaa attttcattc
     4621 aattatcatt ttcaattgca ttttataaat cattttgtat gtaatttggt atgtaagtta
     4681 aaatgaaaaa agtagtccat tttgaagtac attttgtcat tttgtactcc aaaactgaac
     4741 tacttagtat agattactgt tgcttcttta ctaatttagg tttacttgtt aagaaagatt
     4801 atttacgcaa atgttcttca acaatttgct gagatttatc agctgtatct tccacttcat
     4861 cttttgcttt ttctaacttt tgaatatatt gtttcaagct tgagttttca gcagttgctt
     4921 cgtctaattt cttttgtgta tctgttaact gagtttctac atttgttttt tcttgtgtca
     4981 gtgttgcgat ttgttgattc aaaccattta cagtattttg taattctgaa agttttgctt
     5041 gtgcttcttg tagtcttgct gtccaatctg cattcagatg attgatttca tcattttttt
     5101 ggttgatctc atctagtttg acattgattt cattttgttt gctttgtagt tgtgcatcct
     5161 tgctgactaa ttgactttct aagttttgtt tttctgctgc cgattgattt ttttggtttt
     5221 ctaattcatt tacttttgtt tggtattctt ggacatctgc ctttgaatct tgcaatgtct
     5281 gttctttttg tgctagtcga gcggtaagat ctgtaatcgc ttgctcttta tctgtcaatg
     5341 tatgatcaag ctgtgtcaga ttctcattga ttgtatcaat atctgtctct ccaccccaca
     5401 aaataatttc atttgcgtac cgcgtgcctg tgtagccaat tagacataga aatgcaacga
     5461 caatcccacc agtaataaat ttctttttca tttgcatagc tccttaatcc aatactttta
     5521 catgctaaaa gtaagtgatc tcaaacacaa tgtcaagcgt ttttaaatta catatgtaat
     5581 tttaa
//
LOCUS       DACCVZ010000134         5560 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.138, whole genome shotgun sequence.
ACCESSION   DACCVZ010000134 DACCVZ010000000
VERSION     DACCVZ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5560
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.138"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            317..676
                     /locus_tag="IVW63_002743"
                     /pseudo
     CDS             317..676
                     /locus_tag="IVW63_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(981..1943)
                     /locus_tag="IVW63_002744"
     CDS             complement(981..1943)
                     /locus_tag="IVW63_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7860966.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGESI"
     gene            complement(1945..3384)
                     /locus_tag="IVW63_002745"
     CDS             complement(1945..3384)
                     /locus_tag="IVW63_002745"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HAP7860967.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            3569..5515
                     /locus_tag="IVW63_002746"
     CDS             3569..5515
                     /locus_tag="IVW63_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HAP7860968.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1764 a          971 c          932 g         1893 t
ORIGIN      
        1 ttataaataa ctcataaaaa atattttgac tttcaaaatc acttttgcta ccagaagttg
       61 aggcgaagtg ttttaagcat agttgtaccc tagtttgacc gttaaaaata aataacgatc
      121 gctagagtgc aactatgttt gtttgctcta ccgtcagcgt cggcttggcc tctcacatcc
      181 attaccgtcg ggatcatctc cgttacatac ccttacaaaa tacgccctgt aagcattgca
      241 tgaaaccacc gtgcatttgc accgtatttc cgccctagcc gttcaaatcg gtcgctacca
      301 ccattcagaa acacgtgcgg taatggaagg tttggaggaa gctatccaga ccactaacga
      361 ttgtccctat cgtcgtacgt ttcactcaga tcaaggttgg gcgtatcaaa tgaaagctta
      421 tagaaacaaa ttgaaggagt acaaaatctt tcaaagcctg tctcggaaag ggaactgctt
      481 agataattca cttatggaga atttttttgg cttattaaaa caagagattt ttcacgggaa
      541 agtttataac tgtttcgagg aattaaaatc agccatcgat agctatatct attactacaa
      601 taatgaacgg ataaaacaga aattaaactg tcaaagtccc gtccaatttc gtaaaacaac
      661 cgttacggtt gtgtaaaaat atcattttag agcatgaaaa aaggagtgga tttctccact
      721 ccaaaaaagt ctaacttttg ggggtcacta catttttgat cctttttatt tgattaatta
      781 tatccagctg gataataatt ttgggggcaa catttctatc ttactattat cttcctaaag
      841 tagtagactt tcttattggg aaaaattaca acaaaaagga gtggcttagt tgacaactcc
      901 tttttgttta caaatcaatt ggatatctac aaattgtatt ttctaacgga ttttatagac
      961 attaaaaaat taatttgacg ttaaatactt tctccagaaa gtattgagat tggtaaaata
     1021 taatccttat ttgtcttttc gcctttaatt tttttcagaa gaatatcaac aataagactt
     1081 gcaatttcat caattggttg tcttattgtt gtcaattgtg ggaaaaattt ctcaatgaaa
     1141 gaggtaccat cgtatccaat aatttttaaa tcttctggga tattaagttt aagttgatga
     1201 gcaattttca tagtgagaat ggctgttaaa tcatcagaaa caaaaatacc atctggtttg
     1261 tgatttataa tagttgactt tatttccatt tcacgacgga tagtagacag attattagga
     1321 attttgaaaa tttttccatt tggattttga aaagaaaaac ctagtgcacg taattctgtg
     1381 ggagaatccg tgttatcatt tcctgtaatc ataatggtat tttgacaacc atttttttgt
     1441 aaagtcttag ctgcaagttt tcccccttca aagttatctg aagaaacaat ggaaacatta
     1501 ggagctaaat ttctatcaaa agcaacaata ggtgctctca cacgctcata atcagcaatt
     1561 ccaagattat ggcttgatga gattatgcca tcaacttggt tggcttcaag catttcaatg
     1621 tattctctct ctttagcagg atcattttga ctattgcaaa taatcgtttt atatccatgt
     1681 ttaaataact ctatttcgag atactcaatg agttcagagt aaaagatatt actaatatta
     1741 ggaaaaataa gaccaataag ctgaggtgac tttccttgaa gtccacgtgc taaattattt
     1801 ggtttataac caagagtttt catagcttca tgaacttttt gttttgtttt ttctgataaa
     1861 tatcccttat tattaatgac gcgtgaaacg gttgttgggc taactccagc taattcagcg
     1921 acatcagtta attttgctac cattttaata ttttaattca aagtattttc cagtaggttc
     1981 gcctgatttg atttgaatac cattttggtg attttcaggg aatacacgac tagtaaacac
     2041 tttttctcct ttattaataa aaatctcaat gattgagtta tctacaaaaa tgttagcagt
     2101 tgtttcttta gtatcaattg agcattcacg aatcgtacca aagtcagtgg catattgaat
     2161 gcctgctttg ctgcgatcta aaataatttt tccttctttg gtatctacaa tcaagctaag
     2221 tccatttcct ttactatcag agaaaagaag taactccgat ttctgatttg gaggaaaagt
     2281 tagttcaagc tcataagtat tatttgtttc tgcttttgct gtaaattgtt cagaactagc
     2341 acgtaatgat gtaatagctt ctactggata ttggtaaagt ttaccatctt ttattgaaag
     2401 ttcttttaca agactcattg ctccctgata atcatactta tcagttggat aatcgatatc
     2461 aggtagtcca atccaactga caatcagagc acgaccatca ggagtattga atccttgagt
     2521 cgcatacgct tcaaatccat aatcaagatt ttgaatttct gaagcgccca caagttttac
     2581 tttttctatg tcaagcgatt gacagatctt aaaagtattc ggatagatat tcccataatt
     2641 tagctcagat ttatccaacc cttgaggaca ataaatgaga acaggttttt tgtctacaaa
     2701 tactagattt ggacactcaa tcatgtattc tgaaccagtg ccgccaaaat caaggttgcc
     2761 aacttcctcc catgtttcca cgttattgtc atccgctttg taaagtttga taaagcctga
     2821 tttttctaaa ttttgtgctc caacaatcgc atacaattgt ccttcataat taaacatttg
     2881 tggatcacga aaatgatcag ttacatcagc aggtttatga ataagaacat tctcaccttt
     2941 cgtaatgttg tagtctttat ccatccatgc tccgatttga agtgtatcac gttcccaatt
     3001 ttcatttcga acgtttcctg tatagagtaa gaatagattc ccctctattt catatgcaga
     3061 accggaataa gcgccgtggc tatctcgttt tgtgtctgga agaagttctg ctcctgttac
     3121 atgaaaatga actaaatcat ctgattcatt gtgtacccat tctttcaacc catgagcagc
     3181 tccaaatggc caattttgat aaaaaagcgt atattttccg ttaaaaaaag aaaaaccatt
     3241 aggatcgttt aacaatcctg ttttaggttc gatatgatag ctagcacgcc aaggtgatcg
     3301 ttttacatta tccttaattt tatccatctc atctttagtc caatcagaat aagcacgata
     3361 tcgtatttct cgaggtaagt tcatatttta ctccttcaat ttatcttttt acaactagta
     3421 tggtaaacgt tttccgttga aaaatcaatc atttcattta aaaaaataaa ctatatgaca
     3481 aacgtttgac atatttttaa gatatgctaa aataaatttg catttcagtg aaccgttttc
     3541 acgtaaaaat aaaaaaggag tgattcgaat gaattacagt aaagtagctt ccgacgtaat
     3601 acaagcggtc ggaaaagata accttattgc agctgcacac tgcgctacac gtcttcgtct
     3661 cgtactaaaa gatgacacga aagtgaatca aaaagcttta gacgaaaatc cagatgtgaa
     3721 aagcacattt aaaattgatg gacaatatca agtgattatc ggtgcaggtg atgttaattt
     3781 cgtttatgac gaacttatca aaaaaactgg actttcggaa atttcaacag atgatttaaa
     3841 acaaattgct agtaaagata aaaaattcaa ccccattatg gcattaatta aattattatc
     3901 agatattttt gttccaatta tacctgccct tgttgcaggt ggtttattaa tggcattaca
     3961 aaacttttta acagctgctg gactttttgg accaaaatca attgaagaaa tgtatcctgc
     4021 gattgaaggt atttcctcaa tgatccaact gatgtccgct gcaccattca tgttcttacc
     4081 aattttagta ggtatttcag ctgctaaacg ttttggagca aaccaatttc ttggtgctgc
     4141 aattggtatg atcatgacaa caccagatct tggtggctca actgaatatt ggaatatttt
     4201 tggttatcat gtttcacaaa caaactatgc ttatcaagtt attccagttt tagcagctgt
     4261 ttggatatta tctatattag aaaaattctt tcataaaaaa ttgccatcat ctattgactt
     4321 tacattcacg ccattattat cagtaatgat tactggattt ttgactttca cagttattgg
     4381 ccctgtaatg ttattgttgt ctaatggaat tacagacatt attgtttggc tatataacac
     4441 tactggattt attggaatgg gtatttttgg aggaacatat tcacttatag tcatgactgg
     4501 tttacatcaa tcatttccag ctattgaaac tcaattactt tcagcgtgga caaatggtat
     4561 cggacatgga gactttatct ttgtagttgc atctatggca aacgttgctc aaggtgctgc
     4621 aacatttgcc atttggttct taactaaaaa ttctaagaca aaaagtcttg cttcctctgc
     4681 gggtgtctca gcacttcttg gaattacaga gcctgccttg ttcggagtta acttaaaata
     4741 ccgctttcca ttcttttgtg ctttaattgg ttcaggaatt gctacagcag tagcaggatt
     4801 acttaaagta gttgctgttt cacttggttc agcaggtttc ttgggatttc tttcaattaa
     4861 tgcaacatct attccatttt acgtattgtg tgaattgatt agctttgtag ttgcttttgc
     4921 aattacttac ttctacggta aaacaaaagc tgctggtatc tttaaagcag aagaaattgc
     4981 tgaacaaaca ccagttaatt cttcaaaagt agcaacaaca gatccaatat ctactgatgt
     5041 tgaatcaaca caaacaaaag tttcatcaga aacaattgtt agtcccattt ctggtaaagt
     5101 gattagtctt tcttcagtaa atgatccagt cttttcatca gaagctatgg gaaaagggat
     5161 tgccattaaa ccaaatggaa acacggtcca ttctccagta gatggtacta ttcaactcac
     5221 gtttgaaact ggacatgctt atggtattaa atcaaataat ggtgctgaag ttctaattca
     5281 tattggtatt gatactgtat caatgggagg aaaaggattt acacaaaaag ttactactaa
     5341 tcaaaaagtt agaaaaggcg atattcttgg agcatttgac cgttcaatga ttgagaaaga
     5401 aggtcttgat gatacaacaa tgattattgt gaccaatact tcggattatt cagaagtaaa
     5461 tatagtagct gaaaatacag tcactgaggg tactgattta cttgaaatca aataaatata
     5521 tttccctgag taaagatgga attttctttc caaaatcaaa
//
LOCUS       DACCVZ010000135         5323 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.139, whole genome shotgun sequence.
ACCESSION   DACCVZ010000135 DACCVZ010000000
VERSION     DACCVZ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.139"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..2008)
                     /locus_tag="IVW63_002747"
     CDS             complement(<1..2008)
                     /locus_tag="IVW63_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP7860969.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
     gene            complement(2024..3020)
                     /locus_tag="IVW63_002748"
                     /pseudo
     CDS             complement(2024..3020)
                     /locus_tag="IVW63_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3218..4459
                     /gene="sstT"
                     /locus_tag="IVW63_002749"
     CDS             3218..4459
                     /gene="sstT"
                     /locus_tag="IVW63_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAP7860970.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            4606..5241
                     /locus_tag="IVW63_002750"
     CDS             4606..5241
                     /locus_tag="IVW63_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAP7860971.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
BASE COUNT         1627 a          860 c         1015 g         1821 t
ORIGIN      
        1 ttttttgtgt cgcccatgtt gcactgtact ggttacctgc aacaagatca tattgtatca
       61 gacgataatc ttctagaatt tctttttgtt tctcagttaa atttttttct tggataattt
      121 gactatcctc tgtaacaaag acctgttttc cattaaaacg attagacaag ctttctgtag
      181 gatcaattgt taatgcaggt agatgattag atacttctgt caacaacgca tagtaaggag
      241 ttactttgat attcgcatgc tcaagagcca tagcaccaaa gttattagga gcaacaactt
      301 ctttatttaa cgtagctgct tgttcacgac tatacttgtt gttataaatg aaataatctg
      361 tctggtgctg ttctaatcca tattttttcg aatcattccc actatagatt gcgggtaaat
      421 ggtcaccata aaaaacaaag gtaatcggtt tatcgatttt gtcgatttct tggatgaatt
      481 tttttactgc tgtatcggta tagtgaaggc cttgcatata agtttgtaat tcttttcttc
      541 tattaggaat gacagcagtt ccttcagcag tgtagttcaa ttcactatag taatcatcat
      601 aaggcatatg gttttgcata gtggataatt ggatgaattg tgacgtttct gtattgcttt
      661 gtaaagcttt caaggtttct ttgtatgctg aatcatccga tatgcgtggg ctttgttcta
      721 ttttatccgt ataagttaat ttatccggac tgtctaaata atagaacctg tcaaaaccaa
      781 atttatcaaa cacttgtttt ctgcgataaa gagcagctgt aaaaggatgg atggctattt
      841 tttcatcgaa tagatcggta atatttggac ttattttctg acgctccact agctgggtat
      901 aaggtgtaac taacgaagca gacaggttac tgatactcaa gcctgtcagt ccttcccatt
      961 ccatgttagc tgttccgcca ccataaccga cggataacat caatcctcct gttccttctg
     1021 ttataatgct tttgatgtaa ggaatagggt ctgtaggtac tgtcagatta gggacacgtg
     1081 caggatcact gaagctttca cttaaattga gaacgatcgt ctgattgttt aaccagtcac
     1141 ttcttgtttg gttgatttca tctgcctttg tgttgtactt tttcattatt ccattaattt
     1201 tttctttcga atagccagca ggttcttcca tgattttaat gtcgatattg tttaggaatt
     1261 gaatgactgg tccgttatct tttacggcgc cttgctggtt aaagaaagtc ttgtttactt
     1321 taaataaatt aaacagcaag aaagaaggcg aatttttgtg attaatgaaa aagacacccg
     1381 aaaaacatcc taataataca gcgatactga taaatcgacg tttccaatga atcttcaagg
     1441 aatactgttt ttgtagtcta cgttgtacaa taatactagt aatcaataat aggagaagga
     1501 tcaatccgcc cacgattaat aagactgggc taaccatcga taatagttct gacaatccgg
     1561 tcagtatttt taaatctgaa ggaaagacag gctcttcccg catttccatt ttgattactg
     1621 tcgaaatagt gagcagtaag ttaatgatca aggtagcagt caaggcgtac caaaaacgat
     1681 tggaaatcaa caatagtaag aagaaaaatc ccataataat gatgattgtc aggatcatgg
     1741 gtgcttgtcg ctgagtaaat atttttaagg caacctggat agtttctttc caaccttctt
     1801 ttggttctaa aacgaaaatc tgcacgaagg taaagcagta aaaaaatgct gcaactaaaa
     1861 aataactttt atgaacaaaa agccaatgaa ttcttttttt ccaacgctga gttaattgtt
     1921 caatcgaatc aaaagcgaag tattcgatga aacgatgaat gaaacggatt ttttgtatat
     1981 aaaataaaaa gataactagg agggacactg ctaataaata gcaaataaaa aactgcccga
     2041 tatttatcag ccatgccttc cctgagtttg gaaattcacg tttcataaat gtagatacgc
     2101 gataagaaac taaagggaaa ttacatataa cttgagtgac aatcaaaaat acagcaagaa
     2161 aatttcctct tccttttata cctaatttat cagatagcat ttctaaaaat aaaaacgaag
     2221 agaaagtata atacattgcg aagagagaat atggtttaga aaacctcagc gctgtatctg
     2281 tatttcctct gatgatgagt gaaatttgtg tcatcaaaat aatcaaaccg aataaaacaa
     2341 tcaagctgat aaatacttga ggaagcttat agcggacctt ttctttccag ttccattctt
     2401 tcaaaccata acccattaaa aataaataaa aaatccataa aatactctgt ccattctgta
     2461 atgcaaacgg gtctttatta aatagagtag agcagccaac taatccaatt gttaaaaata
     2521 atagtagata tttaattgtt gttttcgata atttatttaa aaatccaact gtataaggaa
     2581 tactacaaaa aagcaaagta caagaaacag cataagtaaa gtaattctga ctgataggtg
     2641 ttaggataag ccaataatca cgaatattca agctgccagc ttgtacgtaa aaaaaagata
     2701 ttgcaaacta gtgtggctat taggaatata aaggcaaaac gacttaaata atgtaaaact
     2761 tttaaacggg cgattttttg atattggtaa cccatgtaaa gtgggatcaa atttgcacca
     2821 ataacaacgg aagtttgtaa aaatgtatag atgtagaatc gaccagggtt tgttgcatat
     2881 gtaggaatag tgactgctga aatcaatata cgctgtaaaa ccatcattat acaagcgaca
     2941 aagattgtca ggaagccata actctccttc tttatttttt tcaagaataa acacctcaca
     3001 aaaaaattgg acaaaaacat aagaaaacgt ttcctgataa gttgcccatt aataacatcc
     3061 taacttagaa tatctcaaaa aacaacgtgt agacagaaaa agtacaaaat tagcaagaaa
     3121 tggttgtttg tattgttaga atttttagaa aattatacct ttagtttctt tgcataaaat
     3181 gatacaatga ttgttaaaat tgtgaaaggg tggtcatttg ttagagaagt ttttggatat
     3241 gtcgttagtt caacgtattg ttgttggtat tttagtcgga atattgtttg gtatcttttt
     3301 ccccacatgg acatttattt caatattggg aacgttgttt gtcagttgct tgaaggcaat
     3361 cgcacctatt ctggtttttt tcttgacgat ggcgtcaatt gccaagcata aaattgggaa
     3421 taagacattc gtgaagccta ttttgatctt atatttagtg ggaacattgc tttctgcact
     3481 tgtagcagtt attgtaagtt caatttttac tgttcctatt actttacaag aaacagtatc
     3541 tgaaaaagca ccgcaaagtt tggaaagtgt tttatctact atgttgacga atgtcacaca
     3601 aaatcctgtt caatctctta ttgatgcgaa ttaccttggc gtcttattct gggctgtatt
     3661 gttgggacta gcttttcgag cacgttcaga atcgacaaaa gagttggtgg atcagatatc
     3721 tatagcgttg tcacaagtcg tacaagtgat tattgcattt gctccgatag ggattttagg
     3781 attggtttat caatcaattg ctacgactgg aatagctgga ttggcagagt atctgcagct
     3841 tttacttgtt ttgatcggta cgatgctgtt tgtcgcatta gttgtgtacc cattcctcac
     3901 gtttttgttt attaaagaaa atccctatcc attgattttc ttttgtttga aagaaagcgc
     3961 acttcccgct ttctttaccc gaagttctgc cgcaaatatc ccgataaaca tgatgttggc
     4021 tgaaagattg aaattgacaa aagagtctta ttccatatcg atcccgttag gtgctacgat
     4081 caatatgggc ggtgccgcga ttaccatttc cttgatgacg ttgactgctg tacattcttt
     4141 agggattgaa gcaccttttg ttttgaaagt ccttttatgt attttgtctg ctttagctgc
     4201 ttgtggagct tcaggtgttg cgggcggttc actgttattg attccattag catgtagttt
     4261 gtttggtatc tctaatgatg tcgcgatgca aatcgtcggt attggattta ttatcggtgt
     4321 tatccaggat tcaatggaaa ctgccttaaa ttcgtcaagt gatctgttgt ttactgcaat
     4381 aggagagcta ggcgcgcgta aaagaagtgg ggaaaaaatc aaattgaaag attgtttaga
     4441 tggattaagt gaacgttgaa cgttagatat ttagtatttt taaaatgatt cgagttttta
     4501 atgagttata tagatgttcg tgtaaataga ggtttctgtt aaatcaagat aaagtcgctt
     4561 ataataacaa ttaaaagcat aggtaattgt tattggaggc gtatcatgga ttttttacgt
     4621 aaatttggtt ttttcttttt attattaggc gtgctgagtg attttttgac tccgtacgta
     4681 ttaggattgt attatcctga attagatcaa atgaagagcg tgatcagtgt atttggagag
     4741 gtttccagtc ctgtaagaaa agcgtttctt atttggtctg tggtttcagg gatctttttc
     4801 atcctgtcat tgcctgcatt gtatgctgca tttgtaagta catctcgtgt gttagctacc
     4861 ctagttacag cagccatcgc gttctatggt ataggtgatt gtatctttac aggtttgttc
     4921 agtatcaata cccatgaatc ttcgtggaat gtctcgacat gggtccataa tatcggatca
     4981 ggtttaggtt acagtggttt tttattgttt ccagttcttc ttttcttgat ctatcgaaaa
     5041 aatgggcaaa tggacgtaag ccacttatac cttggactgt ctgtgatcag tttgcttttt
     5101 gcggcgattt atggactggc aagaattcct tctataaatt cttggccatt actgaataaa
     5161 ataggttttt gccaaagaat cagttttttc tttaattatg tgcccattgc ctggttgagt
     5221 atcttgcatc tcaaacagta aaacttgagc cgtcaaattg aacagtcagc ggatacttca
     5281 tccggtggct gttttttgtt tttctgaaat atatatttcc aca
//
LOCUS       DACCVZ010000136         5310 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.140, whole genome shotgun sequence.
ACCESSION   DACCVZ010000136 DACCVZ010000000
VERSION     DACCVZ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.140"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="IVW63_002751"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="IVW63_002751"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAP7860972.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="IVW63_002752"
     CDS             complement(1297..2133)
                     /locus_tag="IVW63_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7860973.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="IVW63_002753"
     CDS             complement(2317..3534)
                     /locus_tag="IVW63_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP7860974.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            3917..4000
                     /locus_tag="IVW63_002754"
     tRNA            3917..4000
                     /locus_tag="IVW63_002754"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..5237)
                     /locus_tag="IVW63_002755"
                     /pseudo
     CDS             complement(4240..5237)
                     /locus_tag="IVW63_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1653 a         1081 c          838 g         1738 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagttaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca
//
LOCUS       DACCVZ010000137         5309 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.141, whole genome shotgun sequence.
ACCESSION   DACCVZ010000137 DACCVZ010000000
VERSION     DACCVZ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.141"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(59..1198)
                     /locus_tag="IVW63_002756"
     CDS             complement(59..1198)
                     /locus_tag="IVW63_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP7860975.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(1507..2220)
                     /locus_tag="IVW63_002757"
     CDS             complement(1507..2220)
                     /locus_tag="IVW63_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAP7860976.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(2474..3175)
                     /gene="nagB"
                     /locus_tag="IVW63_002758"
     CDS             complement(2474..3175)
                     /gene="nagB"
                     /locus_tag="IVW63_002758"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAP7860977.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            3409..4941
                     /locus_tag="IVW63_002759"
     CDS             3409..4941
                     /locus_tag="IVW63_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP7860978.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(5132..>5309)
                     /locus_tag="IVW63_002760"
     CDS             complement(5132..>5309)
                     /locus_tag="IVW63_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7860979.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         1747 a         1080 c          892 g         1590 t
ORIGIN      
        1 aaataaaaag agtttagcgt acagatattt taaatgtaca ctgaactctt ttttatgctt
       61 attcacttgt ttcttccagc acttttggac tgtctaactt ttccgaaaca tgttccattc
      121 ttctcaataa atagattttc cggatattta atattatcgt cttaatcact gcatagacag
      181 gtatgcaaat cagcatgcct aatattcctg cgacacttcc tgctccaatc aataccaaga
      241 tgatcgtcaa aggatggata ttcattgatt tcccaaataa caacggcttg atcaaatttc
      301 catctaattg ttggatcact aaaatcgaca acgccatata caaagcttga aatggagaga
      361 taaacaaacc gacaatgatt gctggtaccg ctccaataaa agggccgaca tacgggataa
      421 tattcgtgat tccgcaaatg accgcaagca acaagctata aggctgatcg aatattctca
      481 ttgccaaaaa gctcattaca ccaataatca aagcatctaa gatcgtactg ctgatatagg
      541 cagataatgt ttcgtttaat tcttttaccg tttggcgtaa ctctttacga atcgctttcg
      601 gaaagaagtg agacaacgca tcaataaatt tgtgcccatc cttgaacata aatagcaaaa
      661 taaatggaac ggtaaataac aaaataaaaa attgcatcat aaatgaaatg atttttgaga
      721 cacttgcaga taaactgact aatatgatat tgaacaaatt actaagagat aaatttgctg
      781 atgctaattg ttcttccaaa ttgaaatttt taaactcttc ccgctgcgcc aattcattta
      841 accatttgct tgtttcatct gcatacattg gcaagctctg ggtcaattga attgtctgtt
      901 ccattaactg aggcactaca ttcatgacag ttaaaacaac taaaatgatt acgaccaaaa
      961 acgtcaataa aaaaccgaac actctcggga tccgatgctt ttcgagaaaa acaacgattg
     1021 gatcgaacat ataatagata aaaccagcaa caagcaatgg taaaaaaatt gccgaaagca
     1081 ttttcaatat tggactaaaa atattcggca tttgtaaaat aaagtacacg ccgatgatcg
     1141 tgagtactag ctccactgtc cagaaaaata attttgattg tttaaaacgt gattgcatac
     1201 atctcctcca aggtcctttg atacttctat tctatcattt aacaaagagt tacgcgctga
     1261 gattttcatt tgcttaaaaa aaacaaaaaa aataaacata ttttaatgag tagacgagta
     1321 cttaaacaaa aacacggttt ggagtagtga caaaaattat actgcagtcc ctttttccaa
     1381 ataaacggtg ttcaaaagct tgcatcttcg taataagccc agccaaacga aaaatataag
     1441 gaactatttt tatttggctg ggcttattac ttgatgtagg acatctattt tacaacctca
     1501 gatcatttat tgcgcaatac tgactaaatg caactttgtg atatttttgt gtacggacaa
     1561 ctcctcgatc acatcggcat aagtgagccc ttttggaaga tcaatcgtat agatattttt
     1621 gtacactcgg tagtcatcaa cgaattttac gtcaaaattc acatcttcga ttacgatatt
     1681 tttctcttca aaataatcgg taagaaaatc tttggtttct tttctatgga taaattggat
     1741 ttctaacttt ttagtcgtag gtacatggat cacgcgtttc actactgtga gtgcaatagc
     1801 aatcccgata aaactgatga tcgcaatgga atagtaaccc atgccgatgg cgatccctaa
     1861 tccagcaatt gcccataaag aagcggcagt cgtaagtccc gtcaccgatt gtttcgtgac
     1921 gatgatcgtt cccgcgccta agaaaccgac accactcacc acttgagcaa tcagccttgc
     1981 ttcatctgaa cgaatcgttc cagcaagctg tggatactct aaagcatctc ttaatgcacc
     2041 actagcgatc tcaacttgga tcaatgcaat gatacatgct cccatacaaa ctaaaatatg
     2101 cgtacgcata cctgctggac gatttttata ttgtcgttca aaaccgattg ctccgccaaa
     2161 tagcatagcg atccctaaac gtaaaataat ctctggaatt gtcaatacca tatcattcat
     2221 ctaaacaccc tccagtccaa tatatcatgt ctgaaaggag cagacaaaaa aagtgcaatt
     2281 tttacctctt acgaaaaaag gactgtgaca aaatttttgt catagtcctt tttatgaata
     2341 aacggtgttc aatcagctga ccctcggtat tactcaacaa acggcaaaat atggggagct
     2401 atttttcctt tgtcttctct aatactcagg tcaaaacgct gatttcacaa cctctttagc
     2461 ctactattga aaattacaac ttacttgctg cttcttcatc gatgatcaca acaacattgt
     2521 cgtgattttg caatacactt gctggcaaat gattcgttac aggtccttca atcatccctt
     2581 tgattgcatc agctttgctt tcgccaaatg ccatcaagac gatttcttta cttttcataa
     2641 ttgaaccgat tcccattgaa acagcttttg ttggtacatc ttctgcttta tcgaagaatc
     2701 gtttgtttgc attgattgtt gattctgtta agtcaactac tgaagtcgtt ccgtcaaatg
     2761 aagcaccagg ttcattgaaa ccgatatgtc cattttgccc gattcctaag atttggatat
     2821 cgattggatg tgcatcgatg atttgatcat actttttgca tgctgcttcc agatcttctg
     2881 cttttccatc tggtacaaac gtttctttga atggtttttt atcaaataat tggacatcca
     2941 tgaaatgacg gtagctttgt tcatctgaac cgcctagtcc aacgtactca tctaagttta
     3001 cagaagtcat ttcactgaaa tccaaatcgc ttgaagtcat ttctttatat aaagtaactg
     3061 gtgtgcttcc tgttgccaat cctaatactt ttgcaccttt gttcatacct tctttgatga
     3121 tttcaaatgc tttttttccg ccttcttcag cgttttttac acgaatgatt tccatagtga
     3181 ttgctccttt atattttggt atagcccaat tatagcattc tttttttctt tttacaataa
     3241 ttagtataga ccaaattgca tttttttcat tttcttgaca ataaatagga atccgtgtta
     3301 ggtttcataa gatggttcaa tcaaacaatc catgttgcat gaaaaccaag caagtgattc
     3361 actgtggacg ctttatgtct gcagtttttt tatgaaaaag gagttattat gagtatactg
     3421 acattaaaca acattaccca gcaatttggc gacaaaatcc tctatgaagg tgtcgatctg
     3481 caattaaatg ctggcgaaca tcttgggctg attggacaaa acggagccgg taaaagtaca
     3541 ttgattaaaa tcatcactgg tgagatctta ccagatgacg gacagatcca ttggcaaaaa
     3601 aatattcaca aaggttacct cgatcaatat gtggaagtcg atgaaacatt aacaatcgaa
     3661 gaatttctaa aaactgcgta cgcaaaagaa tacgaaaagg aagaaaaaat tgcttttctt
     3721 taccaaacat atagcgagac cttcgatgat tccttgctgg aaaaagctgg gaaactccaa
     3781 acggaattag accaaggagt gttttatcaa atcgacacct tagttgctga gatgagcagc
     3841 gggttgggga tcgatgtctt aggtttagat tcactgttga aaaatctaag tggtggacaa
     3901 cgttcaaagg tgattttagc aaaactactt ttagaaaacc cagatgttct gatcttagat
     3961 gaaccaacca atcacttaga tgatcagcat atccaatggc tgacgcagtt tcttcaggat
     4021 tttgacggtg cgtatatcgt gatttcccat gaccaagaat ttcttgatca gatcaccacc
     4081 catatcgcag acatcgagtt tggaaagatt actaagtata ctggccatct aaaacaagca
     4141 ttgaaacaaa aggaacaaaa tcgcgaaagc tatttgcgcc aatatcatgc tcaacaaaaa
     4201 caaatcgaaa agaccgaagc ttatattcga aaatacaaag ccggttcccg atcaacgatg
     4261 gcaaaaagcc gacaaaaaca attagataaa atcgaacggc tgacgcctcc agcttcagca
     4321 agtaaagctg tctttgattt tccattctcg cctattgtca cgacattagc agtggaaaca
     4381 actgatttag tcatcggata tgatcgaccg ctacttgcac ccatcaattt gaccatccgc
     4441 tttggtgaaa atattgccat tcgaggcttc aacgggattg gaaaatctac tttattaaaa
     4501 acactgatcg gtgagattga aaaaataagt ggcgatttcc acttcccaga taacacaaaa
     4561 atcaattact tttcacaaga tctgtactgg gaaaatccat tagaaacacc actacaatat
     4621 ttaagcagtc aatttccaaa agcgactatc aaagaattac gtcgccaact agctaaagca
     4681 gggttagtta atcaattagc aagtgaacct ctcactacat taagtggtgg ggaacaaact
     4741 aaggtgaaac ttgcacagtt gacaatgaac caaggtaatt tactgattct cgatgaaccg
     4801 acgaaccata tcgatcaaga aacgaaagaa agcttacaag acgggataca gaaatttcca
     4861 ggaacagtaa tcatcgtctc tcatgaacaa gaattttatc aagatcttgt gcaacgagtc
     4921 attgagattg aaccaaaata aacgtttgat tgaatagttg aaaaaaagga gctgtgacaa
     4981 aagttttgtc acaactcctt cttctgaata aatggtggcc aattagctga ccttcggtat
     5041 tagctcaaaa aacggcaaaa tatgaggagc tatttttatt tggctattct tattacttga
     5101 tgcagaacag cttttcacaa cctcttttcg tctatttttt attttcgaga tttctctttc
     5161 ctttaaaaac aactgtttga aagaagaacg cacatccttg aaaaacaagc ccgctaaccg
     5221 ttacacctaa ccagccatac tgctgccaca ttgtcgtccc tagcaatgaa ccagccgcac
     5281 ctccaataaa gtacataaac ataaataca
//
LOCUS       DACCVZ010000138         5206 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.142, whole genome shotgun sequence.
ACCESSION   DACCVZ010000138 DACCVZ010000000
VERSION     DACCVZ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.142"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            33..1367
                     /locus_tag="IVW63_002761"
     CDS             33..1367
                     /locus_tag="IVW63_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860980.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            1354..2988
                     /locus_tag="IVW63_002762"
     CDS             1354..2988
                     /locus_tag="IVW63_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860981.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            3163..3996
                     /gene="msrA"
                     /locus_tag="IVW63_002763"
     CDS             3163..3996
                     /gene="msrA"
                     /locus_tag="IVW63_002763"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP7860982.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            4076..5065
                     /locus_tag="IVW63_002764"
     CDS             4076..5065
                     /locus_tag="IVW63_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HAP7860983.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
BASE COUNT         1824 a          806 c          951 g         1625 t
ORIGIN      
        1 gtttttatta tggagaaaag ttttttaaaa agatagatgc tgctttttta tttagttgtt
       61 tatatacttt tgcaacttat cgaacagttg atatctatta tcgatccgca attgcagaag
      121 caatcgctct tacgattatc ccagctgttt tatattatgc ttatggattg atattcaata
      181 gagaaaaaaa agtcatcgct ttatctgtca gtataagtct acttgtgtat actcatgtct
      241 taactacact attgtgtagt gcattgattg cttgtatgat tatagttcgt ttgtttttaa
      301 gcaagcaaat aaaaaacgat ataaaatttg tggtcgtgaa tttagtaaag gctgtttttt
      361 tgacttgtgc attaactagc tatttttggt atcctatgtt gcagcagatg aattatcaag
      421 aaatacacag tcccttcaaa acagatttgc agctagaagc actttctatt tcagatagta
      481 tcattcaagc gttaaataac gatattacaa catacactat ggggttatta ggattggttg
      541 cgttgatttt tcctttattc atactgaaag aaatggagaa aaaagaaaaa atcatctatg
      601 ttggcgtagt ttctacatgg gtatgcgtaa ctaatttatt tccatggttt ttgtttcaaa
      661 aaacaccgat aagcttgctc cagtttcctt ggcgtatctt aggtatccaa atcttttttt
      721 cttcaatgat cataacgctt gtttttatga aaaagactat gaataaaaaa tattcatggt
      781 taatcattgg cgctactgtg gtgtttctac tcgtcacgtc tatagcagca aaagaaaatt
      841 acgcaaaagt tatccaatca aaacacggtc atattgttat caatgaagaa acactcccac
      901 gttatacaac atcagatatg ggaggattat acgattacgc cccaacagaa gcgataaaag
      961 aaaggcctca cttagaaaaa catgaagtaa aagtaggaga atcgtgggaa aaagggaagt
     1021 ataaagctgc agataataac attacttaca cagtggcaag caacaaaaag caaaaagtga
     1081 cagtaccagt atatgcttat ttaggtacac aggtaaaagt aaacggtaaa gtcgtaaatg
     1141 actcttataa aaaacatggc ttagtgaatg tggatgtaaa tgctggagaa aataagatag
     1201 aaattacaac aaaatatact ccaactgctc tcatggcttt atggatcagt attctgactt
     1261 attgtttagt ggtgtattca agttttaaac gatttgcacc taataagttg aaagattctc
     1321 gatatgtgac taaaaaggag ataaacaaga agaatgaaaa taaataaaaa agtagtaata
     1381 ttgagtggat taattatagt tagtagtata tattctttca tctttttcaa aaatacacag
     1441 agtatttata ccactggaga tctttctttt cacttatctc gaatcaaggg gttatcgact
     1501 atttttacca gtccgattaa ttatgagaca ttcaattata ctggatatgg tgtaaattat
     1561 ttttatccct ttctgacttt ttttccagct gtaatgttat attggatgac aaaaaatttg
     1621 attgtaagct atattattta cgtttggtta ttgaacttgt gtacaacact cgtagcttat
     1681 cattatggcg agcggttttt aaaacaaaaa aaagcggcat ttttatttag ttgtctctat
     1741 attttctctg cttatcggac agtagacatc tactatcgtt ccgcaattgc cgaagctatc
     1801 gcaataacac ttgttatccc tgtattattt tatgcttatc aaatcatctc tggaaaagaa
     1861 gaaaagtatc cgtctgtaaa gctagcattg agtatgagtt tgctagtgta cagccatgta
     1921 ctatcaacat taatgagtac agcattaatt atcattttta tttttattcg tttggtttct
     1981 aaaggtttca agaatgcaga ttttattgct atatttaaaa aattatttag tgcggcagga
     2041 atgacattgg ttctgacgag tgctttttgg tatccgatgt ttgaacaaat gctctaccaa
     2101 aaaatcaaca aacctagcgt gacaaattta tatgctcatg catctaatgt gttcgatagt
     2161 ctgactgaag ctatgaacaa cgacttaact acttactcaa tgggactagt tggtctgtta
     2221 tctttatgta ttcccctgat tttatttaaa aaattaacaa acatagaaaa aaagatttat
     2281 tatggtacgt gtttgacttg gctagctaca actagtttgg tgccatggta tcttctgcaa
     2341 aatacgccag ccaaattgtt acaatttcct tggcggatct taagcttgca aataatattc
     2401 tcttctctga tattaacgat gatatttttc aaaaatagaa gatacaataa gacaagagaa
     2461 ctattttatt tatttatgac tgttttgtta ttaatcactt taactgtttc tagtaaaaaa
     2521 aatttcaatc aaaaaataat ttctcagccg ggacatattg ttgtaaacaa agaaacagta
     2581 gaggcgtata ccactaaagg aatggattat tttttatatg attattctcc tatcgcttca
     2641 ttggagaata aggagcatat aataaaacac gaagcaaaga ttggcagtca atgggtaaac
     2701 cttccttata aaacaactgg tagttctatc atatatagag taactaatga gaagagccaa
     2761 gtaatcacac ttcctgtata tgcttattta ggaacgaatg tagaaataaa tcatcaacct
     2821 gtaaaggagc aggtgaatgc taatggattg gtacaaataa gcggagtcaa aggagttgct
     2881 gatattaaag taagcacaag ttatacagta acgactatta tttcttatct tgttacatta
     2941 actgcatatt tatgtttatt ttttaaaata gttttccata aaaggtaaat taacttttca
     3001 tttataaaat aaattgatta aaaaggagaa tctgtcgata aggattctct cttttttata
     3061 cgaaaaatct gtagggggat gaagtaatcg cttatttcct cactttatga taaattacag
     3121 ctaaagtcac tagcttgtct tcttcggaaa ggaggagaat ctatggatga ggaacaaata
     3181 ttcattcaaa cactttataa tctgattttg aatccgaata cacgagattg ggaacgaaaa
     3241 gtattgattc agacaaagaa tgacataaga gaaaatatat ccgttaaaga acagttatca
     3301 aaactagaag caacactacg tccattagct atccgaatga atctgacgcc tgatgtaatg
     3361 gacttttatt tattgattac ggaaggattt gataaggagc aaaaatatga cttttccaag
     3421 catgccatgc aagatgctga ctatcaagaa cgtgcagtat ttgcaggggg atgtttctgg
     3481 tgtatggtcg agccgtttga atcgaaaaaa gggatcctat ctgttttgtc aggatacacg
     3541 ggcggacatg ttgaaaaacc aaattatgat caagtaagtg gtggttacac aggtcatgtg
     3601 gaagctgtgg agatcattta tgacacaaga gaaataagtt atagcgagtt gctgacaatc
     3661 tattggcaaa ttactgatcc cacagataca tttggacaat ttcaagatag agggaagcaa
     3721 tatcgtccag tgatttttta tcaaggcgaa cgacaaaaag aattagcgga acaatcaaaa
     3781 cagaaactag acagttcagg aactttccac caaccaatcg tcacaaaaat cgaaccagcc
     3841 ggtacgtttt ggccagcaga aaactatcat cagcaatttt acaaaaaaca accgaaacgt
     3901 tataaaaaaa tccagcaagc acgtaatcaa tttctgatct atcaacgagt aaaaaacaaa
     3961 tggcaaaaaa atatacgaaa aaatcatttt gattaactcc ttttctttaa aatgtagtaa
     4021 actaaaaata gaaaaaagaa agcgttttaa aaagatttga tgaggaggag aaaaattgta
     4081 tattgcagat agtgcacgtt atgaaaaaat ggaatatcgt aaatccggtc attcaggttt
     4141 gaaattaccg attttatctc tcggattatg gcaaaatttt ggtgattatg atcctatcca
     4201 taatcaaaga gagattttaa gaggcgcatt cgacatggga attacccatt tcgaccttgc
     4261 gaataattat ggaggccctg ctggagctgc agagaaaaac tttgggcgta tttttagaga
     4321 agattttcaa gcctaccgtg atgaactgat tatttctagc aaagcaggtt atcatatgtg
     4381 ggaagggcca tatggggaat ggggctctcg taaatccatc atttcaagtt gtgaccaaag
     4441 tctccaaaga atggggctag attatgttga catcttctat catcatcgcc cagaccctga
     4501 tacacctttg gaagaaacag cagaagcttt gatgcaactt gtaagacaag gaaaagcatt
     4561 atatattggt atatccaact ataatggaga agatacaaaa aaaatgactg aaattttaaa
     4621 aagaaaggaa gcaccgttca ttattcatca gatgcgctac aatatgtttt ctcgtgcact
     4681 actagaagac gatctatctc cagtattaga agaagaaggg ctaggggcaa tcacgttcag
     4741 tccgcttgct caagggttgc tgacaaatcg ttatctacat ggtattcctg aagattctag
     4801 agcacatcgt aaggaaatac cattcctttc agaagaacaa gttggatcaa ctctggaaaa
     4861 aatcaaagca ctgcaaacaa tcgccgtatc acgaggacaa tcattagcgc aaatggccct
     4921 tgcatggaat ttgcgacaaa aatctgttac aagtgtactg gtcggagcaa gtcggttaag
     4981 tcagttacaa gaaagtgttc gaatgatgga taatttagat ttctcaccag aagaagaatt
     5041 gagaatcgac caaattctag aatagaaacg atgtaatcaa actttttatc catatattaa
     5101 aaaaaacaaa agatgacatc aagaatcgaa tgaagatcgt ctgttattga acatcatatt
     5161 ttttgtcgtt caaaataaaa atgatcgaag gctaggagtg aatttt
//
LOCUS       DACCVZ010000139         5155 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.143, whole genome shotgun sequence.
ACCESSION   DACCVZ010000139 DACCVZ010000000
VERSION     DACCVZ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5155
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.143"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..446)
                     /locus_tag="IVW63_002765"
     CDS             complement(<1..446)
                     /locus_tag="IVW63_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP7860984.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
     gene            complement(753..1850)
                     /locus_tag="IVW63_002766"
     CDS             complement(753..1850)
                     /locus_tag="IVW63_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAP7860985.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            complement(1958..3985)
                     /locus_tag="IVW63_002767"
     CDS             complement(1958..3985)
                     /locus_tag="IVW63_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin"
                     /protein_id="HAP7860986.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            complement(4130..4861)
                     /locus_tag="IVW63_002768"
     CDS             complement(4130..4861)
                     /locus_tag="IVW63_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP7860987.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
BASE COUNT         1462 a         1044 c          811 g         1838 t
ORIGIN      
        1 aactttctct tttcaaaaaa aatttgatat ttttttagat ttctttttag tctttgtaat
       61 actttataag ccacagaata actcacgtga tgctgtttag caaaattttc tactgagata
      121 tatttttcct gaaagaaagc caataccatt ttcatagata aagaatccgt tatataacga
      181 gataacagag ctttgctaga acattttcca ttaatttcca gacatatatc caattcactg
      241 acggttactc gcaaattttt ctctagatcg aacttttgta aatcatgttt cagcttatcg
      301 atcgtttttt tcaagagaaa tgtcgatagc gacaactctt cttgaacatt cgatattgac
      361 tctgataaat ttgagcttgc ttctaaatat ttaagtaatg aataacttct gtgatcttct
      421 ttgcttaaaa aaaactcata attcattagt catcagctct ttctacgtat attactttcc
      481 atgcattcac caactagctg gggataaaac tgatttcctg gatccgagtc actgttgtca
      541 gcgattcttg tttgtataat atacatcgtc ctgtcttttt tttaacattt tggagagcgt
      601 tttatttggc ctttctcgcg atcaaacctg ttattagaat tatatcattt actagtatgc
      661 atttttatta ataaaatggt atattttata ttgttataaa aagagcccaa ccatcctaca
      721 ataataaaaa tttactattt gttatcttaa ccttactttt ctttctcttc tttttttctc
      781 aaaacaaaca aaagtatgca taataaaata aacaataaga aaagtgaagc tactaagata
      841 taaatccaat tattgtcttt tttaatcgta acatccgtcg tgttcaattc cttggctact
      901 tttccgtcta ttgtaaaatc tttttcaaat acccattgat tggtatagtt gatcgtagta
      961 tttccttttt ttctcgaaaa ttttccattt tcattttcat ttcctaaaac agtcattgta
     1021 aggtgatatt cacctggggt tagcggttga ccatttaaag cagttggaaa agaaaaattt
     1081 gtattcggcg caatctgcaa tccttctttt tcctcttgat ataaaacttc agaatgtcct
     1141 ttttttgtaa tttttgtttc aataactact tgattgatat aggttttttg atcattttga
     1201 acgtttgcta agatgacatt tcttgcattg atttgatctg gtttaacttc atgaagagta
     1261 aggttcggag caacttcgtt cagtgtctgt tgcatcaaca aagcaataat ataggtgtat
     1321 tcattctcaa tcgataagct ttgatcctta gtttctgttt ggtccttttc cgtctggatt
     1381 tcttggaatg tgatcccacc agccaataca ccatcaaatc gctcattcgg catcctgaca
     1441 tgaaaagcaa cggtttggac acttttaggt tttagcgtca ctatctgtgg atagctcaca
     1501 taatctacca gatcaaagat caggctcatg tctttttcaa tctcgttttt tccgtattca
     1561 accatcacat ttgaattggt ggttgcgcta ttcacagaaa tatcgatttt cacttctttt
     1621 tctgtatcat ttctcaattc cgcttttact tctacttcct gatccggatc aagttgaaga
     1681 tcgaagtaag tttttctctt gtcgatttga ttctctgaag ttatcggcgt cactgaaaaa
     1741 ttaaatgcac tagctgacac tgatatattg ttaaaaagtg cccctaaaat aactaggagt
     1801 gttataaata attgttgttt tggtctcaag aaaatcgctc ctttaatcat atgtaagaga
     1861 agactataac aaaatcttgt ctctgtggga cacaagagcc tatggtacct gtgcccttct
     1921 tgaaactcaa taattttgtt atattcttct cttcctgtta atttcctggg acatctgcaa
     1981 gtatccaaga tagtttcccc tcaaaggttc cgattctttg gttttctaca ggaatattta
     2041 ttctgattcc acgatgagct gtagaatcta aaagagagga caaatcgctt tcaccctttt
     2101 gatcactttc gaaaatcgta acagcggatg tccctataac cgttgtattt tcagaggtaa
     2161 caaaggaaag agcttctgga agctcaaaat ctccatttgt aagaactttc tcttgtttca
     2221 attgtaattt ccaacttcca aaagcccgtt catctataat tttcaaccca cctgaaaact
     2281 gtccgaattc acttaatggt ctactggata ttttatgttt tccaaaattg acatattgag
     2341 gagcagttga gagataaagt ttgccttttc tgtaataaaa atagatatcc tctgtatttt
     2401 cggagaagat gccttctgta ttcgctgaat ccgagtcaaa aacataccct tcaatatcaa
     2461 taggagtttc tttatacttc tctcctattt tcccagtgat tgttttcatt tcagcaatat
     2521 caatctgact gtctttatct ttataataaa catggatatc tatctccttc agctttgcga
     2581 tctttaggtt tatttcattc gattgctcaa tcaaattccc gttttcaagg tattcaaaat
     2641 gcatagtgag tactttttca ggaattactt cctgcaaagt tgtctccaat tcgattatta
     2701 acgtatctcc agcaataaaa taatctgtca gatttagcgt gactcgattt ccggttatca
     2761 agatatcttt ggcatcaatt tgatttccat tgatcaagat atgctcggga atagttaatt
     2821 cttgtgggag gtcgatacta gtctgcattt tcttatattc aagaaaatcc ccctcgacct
     2881 tcaatgtatt tctgatagtt atcttatcgt ttcctccagc ttcagcgatg gccccataat
     2941 cactatcgtt gacttttaca tcagctgttg atgtgacatt cgatggaagt cgcgtgacag
     3001 cgacagcatt ttcttgaaaa aaagtacctg ttgaagaagt aaacccccaa tttacttctg
     3061 tagaaccaaa ctgcctaatg agatcaggta taatccgaga agagcgaccg acaccttcca
     3121 aatcataagt aagacttctt tgctccgcgt cccatttaat tattaacaag cgccatgtgc
     3181 cattagaaag aaatgtagga gctaccgtca cgccagtatg ctctccagaa taattattat
     3241 tatttggttt aggcgtgaca aaagcgacat gtccatgccc tctattatca gcagttatct
     3301 ctcgatccat tcgatcagaa gaaccactat ttttatacgt atcaaactca atcgagagcg
     3361 cattcgcaat gtaaggttgg ccagaacgag tagaatatga gccaattccc atacctggcg
     3421 atccaataac ttgactggga ttactagcca ttctaggatc gccagtcaat gtaaaggtca
     3481 tgccatctcc cgctctatct cgttgatttc ctaagtataa ataagattta aatgtaaaat
     3541 ccgagagtaa actaatcttc ttatttgacc aaatagctcc tctttgagac ctttctgctg
     3601 ggttcaactg cagtaacttc ccattttcca atatggacgt gctagtaccg ataggtgttt
     3661 gaaaaatttt atcgatagaa ataatattgg gatcgtcagg cagctcaacc gcagaaattg
     3721 gtgcatcttc tagtccttgt ttgtccgaac cctcagcttc tacgttgtca gtggtctctc
     3781 cactactcga aatacttaaa tcctcactgc tttcttgtgt ctggttggat tctattaaac
     3841 tgtcgaatgt cgaagtgagt ttgctttctt cgtctcttct atttccatgc tccaactgat
     3901 tcaattccaa agagtaccct atgatcggaa agatattagt cactaagaga ctgcttaaaa
     3961 tgagcacgat cctcctcttt ttcaatatat cttttcctcc tgatcgttaa attcctagat
     4021 gaactattcg tatccaaaca aatttagcct agcctttgac aatttttgct cgattacctc
     4081 gcaagacaat atgactacgt atttattttt aacagttctt ttcagtaaac tagttgttag
     4141 gtgtatcttc taatgtccaa actaatttag tggaatattg ttgcgctaac ttgacagatt
     4201 taccgggtac cgaaagctgt accgcatctt gattttcatt ttcatttgca ccaaatcgat
     4261 agacccaagt ccccacacct gttcctgatt tagcattaat tgctaacgta ttgtttcctc
     4321 ccggtgtcaa cgttaattca gaattcaccg tttgcggcgt atatgttgga tcaaccaaag
     4381 aaacagcctg ccctttcgta aatttcagct gtgctccaac tagttcatcc ccactggcag
     4441 ttttaaactg ttctggttga gagacactta atttccaccc agataaggta cttctcctat
     4501 ctgtcacttg gacatatgtc ggttttctag acccatcgtt catcacatca gcagctgcat
     4561 aatacgtttt atccgcagta gaaatttttt gagtcccaaa tttgaatttt gatccataat
     4621 caatcgataa tgcccctcct gttccagggc ttggaggatc tgatggatcg acaggtttat
     4681 tgggatcagg attctctgga tcaacaggag gagttacacc ctcatctcct gcttcaaatg
     4741 taatcgttcc ttctgtgtta tattcctttg ggtatacttc agttgcagaa acaaaagtcg
     4801 tacttgctac catgctgaat aacatcattg ctgctgttaa tacgatttct tttttcatca
     4861 ttgacattcc tctttcttta tttactaaac atatcagtcg attggattaa tccatagcaa
     4921 aattctgttt tacgatactt atgaaataaa agaacataga cctatatttg gtcctatgta
     4981 tcgattagtt ataaatgatt atcagcccga tttgatttct agtttttatt gcaacttgat
     5041 gcaaacacaa tctagaaata cagctgtcat agcctttaaa ataattcgta agtccccctc
     5101 ctatctatca aaatgtgact tgactgccta gacttcaatc aatattaatt ataat
//
LOCUS       DACCVZ010000140         5133 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.144, whole genome shotgun sequence.
ACCESSION   DACCVZ010000140 DACCVZ010000000
VERSION     DACCVZ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5133
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.144"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            250..1965
                     /locus_tag="IVW63_002769"
     CDS             250..1965
                     /locus_tag="IVW63_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860988.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            1968..3731
                     /locus_tag="IVW63_002770"
     CDS             1968..3731
                     /locus_tag="IVW63_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP7860989.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(3771..4307)
                     /locus_tag="IVW63_002771"
     CDS             complement(3771..4307)
                     /locus_tag="IVW63_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAP7860990.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(4630..5052)
                     /gene="mgsA"
                     /locus_tag="IVW63_002772"
     CDS             complement(4630..5052)
                     /gene="mgsA"
                     /locus_tag="IVW63_002772"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAP7860991.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
BASE COUNT         1537 a         1024 c          988 g         1584 t
ORIGIN      
        1 tattttttat gcagaattca tttatagaaa aattaagtaa aatagacgtt cctatgaatg
       61 aagagactgg catgttttct cattttcttt tttttaaaaa aaatagtcta ttcaatttct
      121 aaagcttctt cataataaaa ctttcattta tgaaaaggct tgttctcttt tcattctaaa
      181 tttcctaagc tacaatgtgg tagtacttgt tttttcaatt gtggacaaat aaataatagg
      241 aggaatcata tgattcagtt attacgttat gcaaaagact atcgtaagca aatcattttg
      301 ggcccgttct tcaaatttct tgaagctgtc ttcgaacttg tcctgccttt aatgatggct
      361 tccttgatcg ataatggact aaaaatgaat gaccgaggaa aaatcattga aatgggctta
      421 tggatggtcg ctatgtctgt gattggtctg atttgtgcta tcatttgcca atactatgct
      481 tcagtagctt cacaaggatt tggtacagag ttacgtaatc agctaatcaa aaaaatcaat
      541 actttctctc acaacgagtt gaatcatttt ggaacagata ccttgatcac ccgaatgaca
      601 aacgacatca atcagcttca gctagcttta gcaatggtca ttcgtttatt gatcagagca
      661 ccgtttttaa gtatcgggtc agtggtcatg gcttttgtga tcgactggga agtaggtctg
      721 tttttcttag cattattgcc tattttctca atcattttat tttttatcat caaaaaaacc
      781 gttcctctct accaaaaagt gcaagaaaaa ctagatcagc tcaatgaaca cgttagtcag
      841 aatcttagcg gtgttcgtgt catccgcgca tttgcgcaga caaaaaaaga aacagagaag
      901 ttcgataaaa gcacaaatga tctagcgaac aattatttac gtgtttccaa tatctctgcc
      961 ctattatcac ctgctacaac cttgatcatg aatgtcggga tcatctgttt gctgacagtt
     1021 ggcgggatca aagtaaatat tggtagcttg caacaaggac aagttcttgc tttgatcaat
     1081 tatatgaatc aaatgctttt ggcactgatc gttgtttcaa acctcgtcgt gatcttcaca
     1141 cgtgccgaag cttcaggaaa tcgggtgaaa gaggtgctag acacagaaaa ttcgattctt
     1201 gaagctgagg tcagtactac tcccgatttt tcttctgaag caattatcgc ttttgaccat
     1261 gttgacttcc gttatactcc tgattctggt ctttctctcc aaaatattac atttcagctg
     1321 aagcgaaata cagtccttgg aatcattggt ccaaccggaa gcgggaaaac gactttgaca
     1381 caattgattc cgcgtttcta tgatgtcagt tccggtacag ttataatgga cggaatggat
     1441 gttcgttctt ggcagctgga tcatctccgt cagcaaattg ctcttgttcc ccaaacttct
     1501 gtactattta ccgggactat tcgtgaaaac cttcaatggg gtaagaaaga cgccacagaa
     1561 aaagaatgtt gggaagctct gaaaatcgct caggcagaag aatttgtccg tcagcttcca
     1621 aatggtttag atacaaaagt catggaaaat gggaaaaatt tctctggcgg acaaaaacag
     1681 cgactgacga ttgcaagagc tttgattgcc aagccagcat tactgatttt agatgactct
     1741 ttaagtgcgt tggattatca aacagacttg gatttgcgta aggcgctaca gacttatctt
     1801 ggcagtacag tgattattat ctcccaacgt gtccgctcta ttcaagaagc acatcatatc
     1861 ttagtgatgg atcaaggtaa gattgctgct cagggtaccc atgaagaatt acttgctcaa
     1921 tcagcagaat atcaggaaat cgtcgcatca caggaggaag aatagttatg aaagtaaaaa
     1981 aattatcctt gcagacgctc cgccgattca ttccttacct tactgcctat gcaaaagaca
     2041 tttggctagc tgtgatacta ggaatcatca atgggattgc aacagttgtg atgacgttac
     2101 aaattggtca aagtatcgat caaatgattg gagaaggaca ggtccgcttc aatcgactgt
     2161 tccatttact tattctattc ggtggtatcg ttttaatcaa cgtagtcagt caatggctca
     2221 tccaagtgtt aagcaatcgg ttagcttact tatccgttgc aaaattaaga aaagatgcat
     2281 ttgctcatct gaatcgattg ccacttcgtt attatgatca aaactcccac ggaaatatcg
     2341 tcagtcgatt tacaaatgat atggacaata tttccattgc aatttctgcg gccttcaatc
     2401 aattattttc tggagtggca atcatcattc tttcgtttat ttttatgatg cgtctaagtc
     2461 cacttctgac attggtcgtt ctttgttcta caccaattat tttccttgtg agttggatcg
     2521 ttgctcgtgc ttcacaaaca aatttcgata gacagcaaag gattattggg gatatctcgg
     2581 gctttgtgac cgaacgaatc ggtaaccaga aaatcgtgaa agcttttcag caagaagaag
     2641 ctagtcaaca gcaatttgaa ctgctaaatg ctgatctata tgaaaaagga caacgggcac
     2701 aattttcttc ttccttgaca aacccgtctt ctcgttttgt agatcacctt gcttatttat
     2761 cgattggttt agttggcggc ctattggcat tgaagagtgg ttcgtcaatc actgttggtg
     2821 tgatttccag ctttacgatc tactcaagtc agttttctaa accatttatc gaactttctg
     2881 gaatcacgac acaactgcaa accgcttttt ctggtctaga acgagcattt gatttgatcg
     2941 atcagccaga agaaaagcct gatttgccag atgcctatgc cttggaaccc aaaaatatca
     3001 aaggaaaagt ctcttttgat catgtttctt tttcttatga ccccaagcag cgtttgatcg
     3061 aagatttcaa ttttactgct tatccaggtc aaaccattgc tatagtagga aaaacagggg
     3121 ccggaaaatc cacacttgtt aatttgctga tgcgttttta tgacacaaca aaaggaacaa
     3181 ttacagtcga tgaccatgac atccgctcta tccaacgtga tacattacgt aaaagttttg
     3241 gaatggtgtt acaagatact tggctatttg acagtacatt gcgagaaaat cttcgttttg
     3301 ggaatccgga agcaagtgac gcagaaatca atgatgccct aaaagcctct tatatgtatg
     3361 aatttgtaga acgtttgccg gaaaaattag atactaagat tggcggtcaa gggttaaaga
     3421 tatcagatgg acaacgccaa ctgttgacga ttgctcgaac gatgatcagt aatcccccta
     3481 tgttgatctt agatgaagct accagctcag tcgatacatt gacagagaaa aaaatccaac
     3541 aagccttctt agcaatgatg gaaggaaaaa ccagttttgt gattgcccat cgcctgtcca
     3601 caatcaaaaa tgcggaccag atattagtga tggatcaggg agctattgtc gaaatgggca
     3661 cccatgatga gctgcttcaa aaagatggtt attaccgacg gctctatcaa gcacaattca
     3721 cagcacaata aaaacaagca gtcttctggg atgggaagac tgcttgtttt ttatttagcg
     3781 tggatcgcta aacttcttaa aatttttttg taaggaatac tacgtcctac gtaataaatg
     3841 gcaattgatt gaatcggtaa ccatattact gtttttaaca ggcggggcgc ccaaacgacc
     3901 cagctgaaca atggcacatg gtacatcaac gcaagccata atggtgtcaa aaataagttg
     3961 atgatcagcg tgacactaag cgtagccaga atggcatttt tccaagtgat ctcttttcga
     4021 tagaaaaaga atccgtagat tgctccttca ataaatgcat tcaatgtaaa tccaataaag
     4081 aatgcagatt tcgagaagag ggccattcct actaaatcag ctaaaactgc gcctatccct
     4141 gaccaaaaag gaccaaaaag aatgcccatg atcacttgtg gaataaatgt gacactgatt
     4201 ttaataaatg gggtctcgat tgctaccagt cgggacaaag tgaccatcaa tgcaatcaat
     4261 aagcccataa tagcaatcat acgtgcgtct aaccggtgtt tcttcatttt tagcatctcc
     4321 tttaagagct gctacatcgt atcatgcagc gaatgcgaaa ataaaaccgc gaacattacg
     4381 tccttcgtcc aagaggcaac atcccatcct cttagcactt aacgctttat tttctactct
     4441 gtattatttt tgggatcttt tcccacagaa actatagcat attttcacat ttactgcaaa
     4501 tacgaaaaac taatattatt gtttatatta tccaatacgt tcgtattata tcgcatatta
     4561 tcagtttgtt tagcttttat agctacatat aggcgaacat taaacgttat ttttccatac
     4621 gcttatccat caaaatgaaa gtggatgctt gtctatttca tggacgattc ttcgaaaatc
     4681 taggaagccg gcttccagtc ctcttagtag cacctcagct gttccgatat tcgtagctaa
     4741 cggaatctca tagacatcag ataaacggat aagtgctgtt acatctggtt catggggctg
     4801 tgcagccagc gggtctcgaa gaaaaatcac caaatctaac tgatcctccg aaatcatggc
     4861 tccaatttgc tgatccccgc ctaacggtcc ggatttaaac cgatggatcg gcaagccggt
     4921 tgcttccgtg atcctctgcc cagtcgtccc ggtagcaaaa agttcatgtt tttccaatat
     4981 tgttttatac gctgttgcta atttcaccat cataggtttt tttcggtcat gagcgatcaa
     5041 agcgattttc ataagagaca ctccttttga tattgttaac atacttattt actccagtgt
     5101 atcagttttt atttcttatg gatatttatt aaa
//
LOCUS       DACCVZ010000141         5023 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.145, whole genome shotgun sequence.
ACCESSION   DACCVZ010000141 DACCVZ010000000
VERSION     DACCVZ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5023
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.145"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            282..521
                     /locus_tag="IVW63_002773"
     CDS             282..521
                     /locus_tag="IVW63_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860992.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(883..1143)
                     /locus_tag="IVW63_002774"
     CDS             complement(883..1143)
                     /locus_tag="IVW63_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860993.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1328..1825)
                     /locus_tag="IVW63_002775"
     CDS             complement(1328..1825)
                     /locus_tag="IVW63_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAP7860994.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1955..2665)
                     /gene="budA"
                     /locus_tag="IVW63_002776"
     CDS             complement(1955..2665)
                     /gene="budA"
                     /locus_tag="IVW63_002776"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HAP7860995.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="IVW63_002777"
     CDS             complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="IVW63_002777"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HAP7860996.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4547..5014)
                     /locus_tag="IVW63_002778"
     CDS             complement(4547..5014)
                     /locus_tag="IVW63_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7860997.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNQASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
BASE COUNT         1528 a         1043 c          769 g         1683 t
ORIGIN      
        1 tatcctccta gcaactattt aaatacccaa aaaaattacc tctagataat atcataccta
       61 cgttttcact tataaatttt ttcataaaaa aagcgtttag aggcataatc gttaatacag
      121 atggtaacca atgtatctgg tttgaactgg gatatcaccc tctccatata tgtattacta
      181 agactaatag atactataaa agacttgata gttttgcatt gattttgcct aatactgagc
      241 ataggtgtat gctaaacgat actataagga gtgtgtacat aatgaaaaga attctgttta
      301 tcagtttatc aaatttattg ttacttactg cttgtgggac ttctgcatca aagaacatac
      361 cttcagatac gcaaatttcg aatagtatcg attcaacaat ttctacaaat gagaaaaatt
      421 ctccggtaga aacttccgat ataaaagttt ctacctctgc aaaaaacagg gtaaagaaac
      481 tgtcagcacg tctcctttat ttcaaacaaa ctctgaatta gcttcttcat cttcttcagc
      541 aaataatgat gatagtttcg cgtttactcc taactaaatg caacctttac aaatgcttta
      601 cgataacaag cctgagctaa atcatcctga tatcagtttt gcattttttg aaatgattgg
      661 atcggatgat ctttttaaaa ctactagttt gtctatccga aaataggaca gttctggcag
      721 tataggtttt tatcgagttt ctccaccagg cctcgttaca gagacagatt ctctaggcga
      781 accttttgaa taaatcaaaa atcatgaaca atcactgcca actaaataaa gtgccttcaa
      841 aagcttggtc ttctcgcttt tgaaggcact ttatttaaat ctttatgaaa ctaaagtatg
      901 ttcatatttg ttgctatagt tatatagata ttctgttgtt tccaactcat aaacgtgagt
      961 atattttgcc actacttttc cgcatttttc taatatttca ttgcgatcga cgtcatgata
     1021 ttcgtctacg cagatcacaa cacaattttc taatttactg attacttctc caaccacttt
     1081 ttgtttcaag ccaataggtt ggcaaatata tttttttcct aaaatgatag tttcgttatt
     1141 catatttcat ccatccttaa tgtttttcca ttatttaaaa tgataatacc attaaaatat
     1201 gattatgaaa atcaataaca cttgtgattt tataaaaaaa taaaaaaacc gaaaaacaga
     1261 aatgcccact gtctttccgg ctctttttat tcttgatttc tcttcttttt tgtttcaata
     1321 gacgatttta gttattaata aatgaaaaag catttatatt aaaatttgct aataaaagat
     1381 ctacatattt ttctagaaat gcttgatcga tttcatcata ccctttcgtt actccgcaat
     1441 cgatatctaa aacaccgatt aaattacctt cttttaccat tggcactacg atttctgatt
     1501 gtgcggctga atcgcaggaa atgtaatttg catgggtttt gacatcatca acgatcaatg
     1561 tttcttgttt ttcagctgat tctccacaaa ctccttttcc catcttgata cgtgtgcaag
     1621 aaactcgccc ttggaacggt cctaaaatca attcattacc atcgaataaa taatatcctg
     1681 caaagacagt ctcaggcaaa gtctcattca acaatgcaga tgaatttgct aaatttgcta
     1741 accagttatc ttctgcttct aataatcctt gttgctgtaa taataaaatt tcgtatgcat
     1801 cttttttctg tttttctgtc cacatgataa aaaccgctcc tttttgatct atggagaaga
     1861 ttatagctca gtttttttgt aaacgctagg tttcctcctc aaaaaaacga gatacgtcag
     1921 gttaatcacc ttgaacgcat ctcgctgtct ttttctattc tgcttgttgg atttctgctg
     1981 ctaaatcagc ataatcaatc gtttcgtgaa caaaagtcgg atcatcaact ggaaaatgct
     2041 gtacaaggga cgagatgcgg ctaatctcaa cttttccttc agccacttca aaatccatta
     2101 catgtccgcc aaatgtatgt gtatcatcga taaaatgcaa gtgaaatccc gctgcagcaa
     2161 ctccttggaa taattcaggc gtaaagaacc cgactaatgt tccttggaca ttgctttgtt
     2221 ggaattctgg ttgagactct gaaatttttg ctagtcttct gtaaggtttt tcttgcttcg
     2281 gcatgatacg gatgtgcata tttttgaata atccagttat cttcactgcc aaaaataggt
     2341 tttccccggc ttctcttact aatatgtctt ttttcaattg ttctccatct gcagtttttg
     2401 agacagaaaa actagtatct ggcgtaaaat ctgtaattgc tgcatagggg gtaagttcac
     2461 ttccatctaa ttgggcaact gagccatctg atcttccttg ataagctacg ccatctaaaa
     2521 agatgacttc accatcaagc ccatgcaatg ttcccaatcc cagagttcct ttttctaata
     2581 tatgagcaat cgtttctgtt ccatccatca agccagccat caaagctcct aatgtcccgt
     2641 gctggtataa gattttttca gtcatgtcga cacttcctta atagaattga tctggtaaga
     2701 ttgtttctcc caatttctca ttatcacggt aatcaatcgg aatatcaata attacgggtc
     2761 cttctgtcgc aaatccttct tctaaagctt tttctaattc ctctacactt gtagctcgga
     2821 ttcctttagc gccaaaagct tctgcatatt tcacaaaatc aactggacca aagtctacac
     2881 ctgacgcccg ctgatatttc attttttctt ggaactctac catattgtag tgtccatcat
     2941 tccaaatcaa atgaacgata ttcaattttt tacgtaccgc cgtttctaaa tcctgggcag
     3001 agaataaaaa tcccccatcg ccggaaactg atacgatttg tgtatttgga cgcaccaatg
     3061 cagcagaaat cgcccatggc aatgcaacac caagcgtttg cataccatta ctgaataaca
     3121 aatgacgagg ttcataactt ctaaagtggc gtgccatcca aatataatga ctacctacat
     3181 ctacggtaac agtcatatca tctgttactt ttgactgaag cgtgttaata acttctaaag
     3241 gatgcaagat acctgcttct ccttttgatt gaacaatgtc ccgctccgtt aattctgctt
     3301 gaagagatgc taaatattct tttgcatctt ctgacacttg ttgaggctct aatgaacctg
     3361 tcaataaatc aagagtggct gagatatcac cgatcaattc tctttcaggc tgcataaaag
     3421 gatcgatttc agctggcgct tcatcgatca caatgatccg cgcatctttt tccgcattcc
     3481 agtttcttgc ttcatattcg attggatcat agccaatagc aataactaga tcacttcgtt
     3541 tcaaaagcat atctcctggt tggtttctaa ataaacccac acgaccaaag aaatgcgctt
     3601 ctaattcacg tgagatcact ccagctgctt ggaatgtctc tacaacaggc aatgctgtct
     3661 ttccaactaa ttgcctgatg gctaacgttt ctttttcact tgatcctcgc atacctacta
     3721 atagtaccgg tagttttgct tctctaatgc gttcagctag gtaacggata tcatctgcag
     3781 aagcagaacc taatttagga tcgctcaatg gcttgatgac attcccttgg acaggtgcat
     3841 ccactacatc ttgcgggata ctgataaagc tcgcgccttt ttttgaactc ttagccatac
     3901 gataagcatt ggcaatcact tctgaaattg tttctggatc ttggatttct gcactgtatt
     3961 ttgtgattgg ctggaacagt gctgcattat ccatgctttg atgggtcaac ttcaatagat
     4021 cgcttcgttt tacttgtccg gcaattgcta aaactgggtc accttctgct gtcgctgtta
     4081 ccaaacctgt agctaagtta ctagcaccag gaccacttgt tgcgataact actcctggct
     4141 ctcctgtaat acgtccgatt gcttgtgcca taaatgcagc attttgttcg tgacgagtca
     4201 cgattaattc aggaccttga tcctctaatt cattaaatac accatcgatt tttgcacctg
     4261 gtataccgaa tacataatca acatgatgat taatcaaact ttctactaca gatttcgaac
     4321 cttgtttcat tttttcgtcc attgaacatc gtccttttta tgctttattt ttaattatta
     4381 gttagaaata atcacaaata attgatacag tttctaaacc tgtttcattc aaaagtatag
     4441 cacgttttat ttcatttgtt tagccatatg tttcaaaaaa tgaaaaagaa tgacagtttt
     4501 tacataaaaa ctgtcattct taattgaaag tttcaattta taaagtctac agatccatag
     4561 ttctcatcaa tttacgattg ttgaagtaaa tcaaaccaaa tacgatagaa ggacctagta
     4621 gaatacacca ttggggcttt acgaaaaaga agagaaacaa acttgtcaat agtaaaaaat
     4681 ctagtaaact cacataccat tttttcaacg tatagtagaa cgctatccgt agaacttgat
     4741 ttggtttcga cgcttgattt ctcacctgaa aataccagta gttgatgcta aaggaaactg
     4801 ataaacaagc aagtaaaaca aacaacggaa tcaaccattt tccataagaa aaacgtataa
     4861 aaaagaaaca atcaaaaatc attatcacac taactatcca agcaaatagc caataaaaaa
     4921 atccctttag ccaaaattgg cgaaacgtct ttatgaacaa acgtactggt gaaaaacttt
     4981 tttcttttgc taattcttct gtcataccta tcatcacgat gca
//
LOCUS       DACCVZ010000142         4924 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.146, whole genome shotgun sequence.
ACCESSION   DACCVZ010000142 DACCVZ010000000
VERSION     DACCVZ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.146"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            84..971
                     /locus_tag="IVW63_002779"
     CDS             84..971
                     /locus_tag="IVW63_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP7860998.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1111..2037
                     /gene="cysK"
                     /locus_tag="IVW63_002780"
     CDS             1111..2037
                     /gene="cysK"
                     /locus_tag="IVW63_002780"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAP7860999.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2273..2719
                     /locus_tag="IVW63_002781"
     CDS             2273..2719
                     /locus_tag="IVW63_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP7861000.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2992..4344
                     /locus_tag="IVW63_002782"
     CDS             2992..4344
                     /locus_tag="IVW63_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase"
                     /protein_id="HAP7861001.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4515..4802
                     /locus_tag="IVW63_002783"
     CDS             4515..4802
                     /locus_tag="IVW63_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861002.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1694 a          812 c         1030 g         1388 t
ORIGIN      
        1 attaaaagta taatttaatt aattaagttt gttttaagaa gagaactttt tattaagttt
       61 ttttattttg aggaggaatt tgaatgcaag agctgaagac ccgcagtgcc cggcaccata
      121 gacctaaaag aaaaatggtg atcaataaaa aagcgattgc tcctttaatt ggaacgagtc
      181 ttttagttgg gccgatgatg gttacagcgg taccgcaaca tgttcatgca gatgaacaag
      241 gatctcaaac agtcgctgat cctcaagcgt ttatcgatca aatcggctgg tctgcgtcag
      301 aagttgctgc aagtaatgac ttgtatgctt cagtcatgat cgctcaagcg ttgttggaaa
      361 gtgcatatgg cacttccgga ttagctagtg cgccaaatta taatctattc ggtgtgaaag
      421 gaagctataa cggacaggtc gtttatatgg caaccaaaga atatgtaaac ggacaatggg
      481 taacgatgaa tgagccattc cgaaaatatt cttcttattg ggaatccttc caagaccatg
      541 cgaatgttct tcgttcaacc agtttttcca cgggcgatta tcattatgct ggcgtgtgga
      601 aaagcaatac aacaagtttt tatgatgcaa cagcgtactt gacaggtcgt tatgctaccg
      661 atccaaatta tggggccaaa ttgaactcat tgattaatac ttataattta acccgttttg
      721 atacgccatc aacaggttcg gctacaacaa ccacaagtac aacaacaacg actactacga
      781 cgacttcaac gtcatcatct tcaacaacag atgtaaatac aaataatggt cagacatata
      841 cagtcgtgtc aggtgatacg ctatgggata ttgcacaaaa atttggcatg tctgttgatg
      901 atctaatggc gaaaaatggc atgtctatgt ccagttattc tttattagtt ggtcaagaac
      961 taaacgtttg atttagataa aaaggcaaag aaattaccat atatggtata tctttgtctt
     1021 ttttttgcta gtcaaagacg aatcactcgc cataaatgaa cagattgtat tatgataagt
     1081 aagaagagca aagacaagga ggaattgaag atgacagcta tctataactc agtcaccgaa
     1141 ttgattggca aaacgccaat cgtcaaatta aataaaatcg taccagaaga ttcagcagat
     1201 gtttttgtaa agcttgagtt ttttaatcca ggaggaagtg taaaagatcg tattgcttta
     1261 agtatgatag aaaaagcaga acacgatggt ctactgaaac caggtgatac tatcattgaa
     1321 cctacttctg gaaatacagg aatcggattg tcgatggtag gagttgcaaa aggatataaa
     1381 gtaatcatcg tgatgcctga gacgatgagt atcgaaagac gtttattgat gaaagggtac
     1441 ggcgcagagt tgattttgac tcctggtgcg gatggtattt ctggatcaat cagagaagca
     1501 gaacgtttgg caaaagaaaa cggctacttt ttaccattac aatttgaaaa tgaagcaaat
     1561 cctcttgtgc atgagaagac gactggtcct gagatacatc aagcatttgg agtaaatggc
     1621 ttggacgcgt ttgttgcagg tatcggtaca ggaggaacga tcactggcgc tggccgagaa
     1681 ttaaaacgtg tgtatccgaa aatcgaatta atcggggtag aaccagcaga atctgctatt
     1741 ttagaaggga aagaagcggg acctcacaaa atccaaggaa tcggtacagg ttttgttcct
     1801 aaaacactgg atacttctgt gtatgataaa gtcctttcta ttagtggaga cgaagcgatg
     1861 gaaacagcta gagaagttgg gcgaaaagaa gggattttag taggcatctc atctggcgct
     1921 gcaattgctg ccgcgctaaa agtcgcaaaa gaattaggaa aaggcaagaa ggtattagct
     1981 gtggttcccg acaatggtga acgttattta tctacagccc tttaccaaga gatataaggc
     2041 acttggtttt tctccagata ggtttatgta aaaaactttt aaagatgaaa agaacacaca
     2101 aaaatttatg atgagaaaaa ttatttgaat agagacgtag aatagtgaac gcgactgttt
     2161 tacgtctttt ttcattaaaa tacaataaaa ttgaattttc ttttcatgtt aagtggattt
     2221 taaaatgtaa aaatagtatg ataagacgag aataacaacg tggggtgttt acatggaaaa
     2281 taagttagtc gaagaggtta tcgaaaagtt aaaaaaagag aacattcgaa tcacacctca
     2341 acggtacgcg gttttagaat atttgattga acatcattcc catccaacgg ctgatgagat
     2401 ttataaagca cttgaacatc ggtttccaaa tatgagtgtt gcgactgttt acaataacct
     2461 tcgcttattt acttcgattg gatttgttca agaaatgaag tacggcgatg cttctagccg
     2521 atttgatttc agttcaaagc gtcattatca tgtaatttgt gaaaactgcg gtaagattgt
     2581 tgattttcat tacccagggc ttgaagatat agaaatggct gcaagcagac tgactgattt
     2641 tgagattaat gaacatcggt tggaattgta tggactctgt ccggattgta aagagtcagc
     2701 aaaaaaggcg caaatgtaaa aacagtttct acaagtgtta tacctaaaaa aagctagctg
     2761 tgtaaaaaaa acgctagctt ttttattttt ttgtctttta ttcacaatct tagatataaa
     2821 agtgaatatt attaaaataa gaatcttgta gatattgggt tcttatgctt gaaaaggaat
     2881 gaaactacaa acaaaccttt gtgaattcac aagcattaaa ctgttgtatc cgttttattt
     2941 ctgttatagt agttttgtcg aaggacaaaa tgttaatcgg agggaccata aatgaaagta
     3001 gtagtaattg gctgtactca tgcaggtact gcagctgtaa aaagtatttt aaaaaatcat
     3061 ccagaagcag aagtgacagt atatgaaaga aatgacaata tttctttctt atcttgcggt
     3121 atcgcacttt atgtcggcgg agtagtaaag gacccagcag gcttgttcta ctcaaatcct
     3181 gaagaattat cttcattagg agcaacagtt aaaatggaac acgatgtaac agacgtcgat
     3241 acagaaaata aaacagtaac ggcaaaagat ctgaaaacag gagaaacaga aacggtttct
     3301 tatgataaat tagtgatgac aactggttca tggcctatta tcccaccgat tagtggaatc
     3361 gatgcgaaaa atgtactcct atgcaaaaac tacaatcaag caaatgaaat tattgcacaa
     3421 gcgaaagaag caaaacgtgt agtaattgtt ggtggtggat atatcggtat tgaattagta
     3481 gaagcttttg tcgaatctgg aaaacaagtg acattgattg atggattaga tcgcatcttg
     3541 aataaatatc tagataaacc attcacagat atcttagaaa aagaattgac agaccgcggt
     3601 gttactcttg cgctaggcga aaatgttact gaatttatca cagatgaaga aggaaaagtg
     3661 aaacaagtag ctacaccaac agatacattt gatacagata tggtcatttt atgtgtgggc
     3721 ttccgtccaa atacaaaact gatcgaagga aaagtagata cactgccaaa cggggcaatc
     3781 aaagtgaatg aatacatgca gacaagtaat ccagacattt ttgcagctgg agactctgca
     3841 gtagtcaact acaatccaag tggcacgcaa aactatattc ctttggcaac aaatgccgtt
     3901 cgtcaaggtt tgcttgtggg aaataacttg acagatcata aaatggcgta tcgtggtact
     3961 caaggaactt caggacttta cctatttggc tggacgatcg gttcgacagg tgtgaccaaa
     4021 gaaagcgcaa ctttgaacga tctagaagtc caagcgactg tatttgaaga taattatcgt
     4081 ccagagttca tgccaactac tgaaaaagta atgatggagc tagtctatga aaaaggaacg
     4141 aatcgtatcg taggtgctca gttcatgtcc aaatacgaca ttacacaatc agcaaatacc
     4201 atgtctttag ctgttcaaaa taaaatgact gtagaagatc tcgcactttc agatttcttc
     4261 ttccaaccac attttgaccg cccatggaat tacttgaacc tacttgcaca agcagcgcta
     4321 ggcgaaatcg aaactgcaca ataaagaaaa agggttgtga cacaattttg tcacgaccct
     4381 ctgtcttttt ttgtgaaaag tacaattagt tgtctttctt cgaatttttt gtcacaataa
     4441 gcagcaaaga taaagctgtt acataaaaga acaagcagct ttatttgatt ttgaaaagaa
     4501 aggtgagaaa gaagatgaat aaagaatatt ttgtccaaca agatgcattt ttagaagatt
     4561 ataaaagtgc ttcgaagaaa ttaacgatca atattgatga gttggcagat caagtactct
     4621 ctcagttgaa tgaaacgcaa gaggaatatt acacgatgcc agcaaatgac gccaaagata
     4681 atgtttctca tcgttttcct ttcagtagac gcatctactc agatgaaaat gacggcacat
     4741 tgaatacaga gtacacatat gaaggtcagc catatgtgct agaaactgat gatgatcttt
     4801 aaagacagtt tttgaaaagg ccgctcatcc ttaagtgatg acaaaaaatc atcacaatta
     4861 ccgatgactg tctctttact atcttttaat cagaaaaagg ggttatgaca agctttgtca
     4921 accc
//
LOCUS       DACCVZ010000143         4892 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.147, whole genome shotgun sequence.
ACCESSION   DACCVZ010000143 DACCVZ010000000
VERSION     DACCVZ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4892
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.147"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(287..649)
                     /locus_tag="IVW63_002784"
     CDS             complement(287..649)
                     /locus_tag="IVW63_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861003.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEGNVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(723..1103)
                     /locus_tag="IVW63_002785"
     CDS             complement(723..1103)
                     /locus_tag="IVW63_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAP7861004.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1185..2360
                     /locus_tag="IVW63_002786"
     CDS             1185..2360
                     /locus_tag="IVW63_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP7861005.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2437..3021)
                     /locus_tag="IVW63_002787"
     CDS             complement(2437..3021)
                     /locus_tag="IVW63_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP7861006.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3222..4220
                     /locus_tag="IVW63_002788"
     CDS             3222..4220
                     /locus_tag="IVW63_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP7861007.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4332..4841
                     /locus_tag="IVW63_002789"
     CDS             4332..4841
                     /locus_tag="IVW63_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAP7861008.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
BASE COUNT         1553 a          915 c          851 g         1573 t
ORIGIN      
        1 ttttttaaat tttttagaaa tgtgatataa catccacttc agaatcaacg ctgttaaatt
       61 tatcatgtat ttcttccttg gtcaactata aattaagcat tactttgtga aatgattttt
      121 cgatcaatta ttattattcg ttatacaacc gttttcaaca tattttgaaa ataaaatgca
      181 ctaaaaaact atctttagca gaacatttca ttgtattttt tggaccaaac aataaaaaaa
      241 gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc tgtattttag aagaaaggca
      301 ctccctctac ttcgtaagtt ccaagaacag agcgcatttg acctggttct tcccaaatat
      361 atccttcgcc taattcttct ctttgattct tttgttcagt ttcaaagaca aacaacggaa
      421 catttccctc tttaatatgt gtatttgtca attccatcaa actaatcttg ctaacatcga
      481 tatgaactat ttcttttaag aaattaagta tattcgctaa accagtcttt ccttcagaaa
      541 gttccgctaa cgcaaattcc aacttgtcat caattgaatg gaccaaaaat tttttagtac
      601 catcctccaa atgcaacata attgtaccag caactctttt gcttgccaaa atttccacct
      661 cgatcaactt gttctatggc ttacataaaa attctagcac attttcagaa aaaatacact
      721 ttttatttct tattttcttt ccgttctagt tcagataatg cttcttctat ccaaataggt
      781 aactgctccg caatagtggt aaatccgatc ttacgatttt tattcgtgaa ataccttttt
      841 ctgcgatatg gaacagctgg atttgttttt tctaacgttc ttaaagataa actgattttt
      901 ttggaatatt catcaatgtc gatgatctga actgttactg gctgtccgac ttttaacaat
      961 gaatggatat ttttcgtata accggattgt acttctgaaa catgaataag tccttgcgtc
     1021 tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc ctgtcacttt tccttcaatt
     1081 atttgtccaa ttttataagt catctacttc cctctcttcg catttatcat tatactgtaa
     1141 atagctcaaa aaaagaagcg acgaaaatga ctggaggtct taagatgatc gaatttgata
     1201 aacagatttc aagaaaagat acagaaagtg taaaatggga cgcaattgct gagacatatc
     1261 aaatggatga cttacttcct ttgtgggtag cagatatgga cttcttgtct cccggtgggg
     1321 tagctaaagc gtttagtgaa tacatcaaac atggaatctt tggttatgcc actctgtctg
     1381 ataaactata tcaggctatc attcattggg aacgccaaca ccatgctgtg gagttgacga
     1441 aagaaaatat cgtttttaca agtggtgtgt taaccagttt agctgcagca gtacaaactt
     1501 ttacaaaacc aggcgattct attttgattc atgacccagt ttatcctcca ttttcctcta
     1561 ttatagaaac aaatcaacgt cacatcgttc gaagctcttt gctagaaaaa aataatcatt
     1621 tcatcatgga cttgtctgac atggagaaaa aaatcgaaga aaacaatgta aaagcaatga
     1681 ttttatgcaa tcctcacaat cctggagggc gtgtttggag caaagaagaa ttgaaacagt
     1741 taagcgaatt gtgtttaaaa catcaagtga ttctgtttag tgacgagatc catcaagatt
     1801 taactttatt cgatcataca tttacttcca tgctaacgat tgatcctaat ttagatgatc
     1861 tactagttgc ttttacttcc gcaaccaaga ctttcaatct agctgcaatc aaaaattcaa
     1921 tggtatttat caaaaatcca gagatgaaag ctgattttga aaaacattta gtgatgaacc
     1981 aacagcacga aatcaacact tttggactga ttggaaccca agcggcttat gagacgggtg
     2041 gagaatggtt aagccaactg attccttatc tagaaaaaaa tgttcaaaca gttaatcagt
     2101 tttttgaaca gtatcttccg aaagtgagaa taatgaaccc tgaaggaact tacttaatgt
     2161 ggttagattt taccgcctat atttcagacg accaagaatt ggagaacact cttgttcgga
     2221 aaggaaaagt cgtattaaat cctggcatca cgtttggtcc ttccggtcat gggcatatgc
     2281 gcttgaatat tgcttgtcca gaagaaactt tactggaagg acttaatcga atcaagtatg
     2341 ctttagagac aatcgattaa atcatttatt caaaataaaa ggacgagacc ttactaggtt
     2401 tcgtcctttt tcataattac tccgtaccat accaaactat tctgaaattt caattgtttc
     2461 aatcactaca tcatgtacag gtcggtcttg tggaccacgt tgtacatttg cgatttcatc
     2521 tactgtgtcc atcccttcta gtacatgtcc aaagactgta tgtcggaaat ctagccaagg
     2581 agttccgcca cctttatacg cttcaatgat ttctgatggg aatccagcac cttctagttg
     2641 tccaagcata ttagctggca catttgtgtt atttacaata aagaattggc ttccgtttgt
     2701 gtttggacct gaatttgcca tagataaagc tccgcgaagg ttgaacagtt cacgactgaa
     2761 ttcatcttca aaactttcgc cataaatact ttcgccaccc attcctgttc cagttggatc
     2821 gccgccttgg atcatgaaat caggaataac gcggtgaaaa atcacgccat cataataacc
     2881 ttttttggaa agttcaatga aattttgaac cgtcttcggt gctagttcag ggaataattg
     2941 aacagtaatg tcaccacggt ttgttttgat aacagctttt ggtccttttt cactttttaa
     3001 atctagttgt gggaatgcca tattgtttcc tcctaatatt tgcatacttc ataataataa
     3061 taacataata cctaacctct cgtaaaaata ctagatttgt tttcttttat ttttcatcac
     3121 tagatacatt ctataactta ccgtttcgat ttcgaattca aacatttttg agaagcattc
     3181 tcaattaaat tctgctatag tgtgaaaagg gaggaatttt tatggaaatc tatgacatta
     3241 caatcatcgg tgcaggtcct gtagggatgt ttgccgcttt ttacgcagga atgcgccaag
     3301 ctaaaacaaa aatcattgac agtctacctc aacttggtgg tcaattagca actttgtatc
     3361 ccgaaaaata tatttacgat attcctgggt atccagcaat aaaagcaagt gaattaatcg
     3421 atcaattaga aaaacaatta actactttta accatacatt ccatttaaaa gaagaagttc
     3481 tctcgcttac tcgtgaagac gaagttatcg agattactac aaataaaggc atccattatt
     3541 ccaaagcagt cattttagct ttaggaaatg gttcattcca gccaagaaaa ttgaatttag
     3601 ataatgctga atcatttgaa aaccacggat tggattattt cgtgaatgat ttgatgaagt
     3661 atgctggaaa aaaagtcgct attgctggag gtggtgattc tgctatcgat tggacgttga
     3721 tgttagagcc tattgcaagc gaagtttact tgattcatcg tcgcccggaa tttcgtgcgc
     3781 acgaacatag tgtatcacgc ttgaaatctt catctgtcaa cttgcttact ccctatctca
     3841 tcgatggatt atcaggcaat aatggggaac tgacagatat ccggttaaaa aaagtgaaaa
     3901 gtgacgagac gattgatttg atgattgatt ctctgatcgt caattatgga ttctcttcta
     3961 atttagaaca tctttcttct tggggacttg atagtaccag aaatgccatt actgtaaaat
     4021 cagatatgtc tacttctatt ccaggcgttt atgcagctgg tgacatctgt acctatgaag
     4081 gaaaagtgaa actgattgct actgggctcg gtgaagcacc tactgcagtg aacaacgctt
     4141 tacactatat taatccaaag gaacgaactc agcctggtca cagcacaagc ttatacgata
     4201 aaaatcttcg tcctagttga ttttttatat ctctttgcat ttcaagttaa acccgaaagc
     4261 agtttcttgc atttttttca tgttccgtta acatgaaata gagaaagaaa aaataaaggg
     4321 ggagcaataa tatggtcgtc aaaactgaga ctttagaaga aaaggcaaga gaactattga
     4381 aggaacgtgg cgtaactgta gaagatatcg cacaacttgt catgttttta caaaaagact
     4441 atatttctga tttgactttg gcggattgta ctgaaagtgt caacagcgtg ctaacaaagc
     4501 gtgaagtaca taacgccatt atcactggaa tccaattaga tatattagca gaaaagaaaa
     4561 aattgatgag tccgttgcaa catattatcg aagatgacga aggcctttac ggtatcgatg
     4621 agatcctagc cttgtcaatc gtgaatgttt acggtacgat cggctttacg aattatggtt
     4681 atatcgacaa ggtgaaacct ggtattttaa aagaactaaa cagccacgat ggcgttcatg
     4741 tccatacctt cttagatgat atcgtcggag cgatcgccgc tgctgctgcc agtcgattag
     4801 cacacaaaga accagaaaaa agaagtcgcc ttactcaata attcaacaaa aaaagaaaga
     4861 aaacgtctat ttagacgagt tctttctttt tt
//
LOCUS       DACCVZ010000144         4815 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.148, whole genome shotgun sequence.
ACCESSION   DACCVZ010000144 DACCVZ010000000
VERSION     DACCVZ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.148"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(81..1889)
                     /gene="pepF"
                     /locus_tag="IVW63_002790"
     CDS             complement(81..1889)
                     /gene="pepF"
                     /locus_tag="IVW63_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAP7861009.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2065..3063)
                     /locus_tag="IVW63_002791"
     CDS             complement(2065..3063)
                     /locus_tag="IVW63_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HAP7861010.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3289..3942)
                     /locus_tag="IVW63_002792"
     CDS             complement(3289..3942)
                     /locus_tag="IVW63_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HAP7861011.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4274..4672)
                     /gene="spxA"
                     /locus_tag="IVW63_002793"
     CDS             complement(4274..4672)
                     /gene="spxA"
                     /locus_tag="IVW63_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HAP7861012.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1417 a         1008 c          746 g         1644 t
ORIGIN      
        1 aaaaaaatac gtcgactccc ttacaagaga gccgacgtat ttttttcgtt tctattcgag
       61 aaaatcaaaa atagaaagcc ttataaacga tcgatcaatt cttctaattc atttagacgt
      121 tgttcaaaca tcgacattgc atcttcaata tatgcagcct gtgtcatatc aactcctgct
      181 tttttcatta cttccacagg ataatcgctg ttacctgctt ttaggtaagc caagtagttc
      241 tctagtgcct ctggttcctg gtttagtatt ttcttcgcca gtgctgaagc agcagaaaag
      301 ccagtcgagt attggaaaac atagtaatta taataaaaat gcggtatccg tgaccattcg
      361 aatttaattt ctgggtcttc ttcgactgct ggaccataat attttgcatt caatttacca
      421 taactatcac ttaggtattc actagtcaat ggcacacctt tttcatcttc cgtatgcatg
      481 aaatgctcga attcagcgaa ttgtgtctgg cggaaaactg ttcctttaaa cccatccaag
      541 taatggttga gtacataagc ccgtacacga gggtcttttt ctgtttccaa taaatactcc
      601 gttaggatat tttcattcgt tgtcgaagca atttctgcta aaaagatgga gtagtcgccg
      661 tacacataag gctggttcga acgagtgaaa taactatgaa cactatgtcc catttcgtgg
      721 acaagcgtaa atagctgatc cagcgtatca tgccaattca ataaaatata tggatttgtg
      781 tcatagcttc ccgaagaata agcaccgctt cgtttccctt tattttcgac aacatcgatc
      841 caacgttcag agaatgcttt ttctacgatg gccatgtatt cttcacccat tggtttcagt
      901 gcttctaaag ctttttcttt tgcttcttcg tacgtaaagg taattggagc ttcccctaag
      961 accggtgtat aaagatcata catgtgcagt ttttccactt ctaataaacg tttccgtaat
     1021 tccatgtatc gatgtaacaa aggcaaatgc ttgtttacca cgtctaccaa agtatcgtat
     1081 acactttcag gaatatgatt attgctcaaa gacgcttctc tggcagagct gtaattacgg
     1141 actttcgctt taaaattatg tccttttata tgtgtgccta aagtagaagc aaatgtattt
     1201 ctaaattgtt cgtaaacact gtacaacccc ttaaatgctg cttcgcgcac ccttcgatcc
     1261 gtgctttcta gcaactgacc atacacgcca tgagataatt ggactatttc accattttct
     1321 ccttcaatcg ttggaaaaac tagatctgca ttattcaaaa cagcaaatgt atcacttgaa
     1381 gcatcaaaga tttcacctgc tccagcaaga agagattcct gctcagcaga taagacatgg
     1441 gctcgattat ctactatttg ctggatataa tggcgataga cttccaattt tggttcttct
     1501 ttgaaatatt gccaaatctg gtcatctgac aattgcaata tttctggttc aaaccaggaa
     1561 acggcttcac taactttcga aaacagactg cttgctcttg cataaagcgc ttggtaatct
     1621 gtatttccag tgtcttgatc gtttttaagg tgcgcatata cataaatgac ttcagtttgg
     1681 cgataaaccc tcaatacgaa ttcaatcgca tttaaaaatt gagaagcgcc ttgatcaagt
     1741 gttcctttgt gtttttcaga ttgttttaac tcttctgata attccaaata tttctcatca
     1801 aactcttggt cgcttgaaaa gatcttggtc aagtcccaag ttaaattttc aggcaattct
     1861 tctcgttttg gcaactgctt tacttccatg aaatccactc cttttcttcc cttagctcta
     1921 tctatcaaaa tagatcatag tctaacatcc acatgtcaca gcatctaact tttctactca
     1981 ttcatgtgtc tgcttccatc aattttagca taactaaatc ttgttttaca tagaaaaccg
     2041 attcctagcc tatttttata cttactattt tttcaaagaa gacaagtgta tgcattcgtt
     2101 aaaaaactgc tgatagacca tctcttcatc aatcatagga aaaagccatt cccttttatg
     2161 ttcttttatt tggcaaagcc atgagttgaa atcaggaact ttctggtttt ccaaggcttc
     2221 ttcgtacaac attcgataaa gaaaaacctg ttcttgtaaa taaaagaaaa accgactttt
     2281 ttgatagatc cacgatgata gatgcaaaag atgtttatga cgcaagtagc attgttcttg
     2341 tatggatact gtattctttt gcttgtgaat aagttggcgt gtcagccatt tcttcccatc
     2401 ttcactcact ttttctattt ttttcatttg gttcatttta atttcgttac tagtgaatat
     2461 ttctttaagg tccctactag aaaaagtcca gcagctactg caaaaggaaa tatgccctga
     2521 tacagtctct gtaatatgat gatacaaata aagcttttgt ttcttgagat cagctttcca
     2581 gcaatgcact cctctttttc tattatagta gcagcaactt ttttctatca atgagaattg
     2641 cgattgtcca agaaaagaat taccaagtat ccaccatact tggtaactgt tattcaaata
     2701 attttgggtt ctttcaataa atctctggtg agacagtcta gaacattgga tttctattgc
     2761 tagattcgcc aacaaaatat ccggcctttg ccgcaacctc ggcaaatagg cttccaaaaa
     2821 tactggttct actgactgtc ccagccaatc catgaagcat tcctttaact gtaagtgctc
     2881 ttttgattct ctttcactaa agaccgaaca gttatctgat ttttgatggg caaaatgagc
     2941 acattttttc tttccctttt tcaaaatcac tctttttcga cagccacgac aataatattt
     3001 ctttcctttt tctgcatgtt tagcaaaaca gcacttatta tattcattca ttgcaagcag
     3061 catttttctc cctctgaact tatttacgtc taagaattta tttacacgaa aaaagagggc
     3121 gtgaaaaagc tattctgcat caagtaataa gaacagctaa acaaaaatag ttcccaatat
     3181 ttttcgtttg gttgggcttg ttaccgcaga tgcaagcttt tgaacacatt tatacgaaaa
     3241 aaagactgcg acacaatttt tgtcacagtc tcttactata atgctgattt atacaaaata
     3301 aaatttcgtt cgctcgatag cattacgcgc catcagacat tgtccatatt cattcaatgt
     3361 ttctggtgta cgatcgctct tttcagcaaa ctccaaaatt cgagcaatct gattctctac
     3421 atccgcttgg ttgagatttt ccatccagaa gtgaacgact aggtaatagc gctcttcgaa
     3481 taaatacaaa tcagtccaag cagactctag ttcgacatct gttgcaagtt ggatcacttg
     3541 ttcaaaatct tcaaaagcaa aagttgcttg tctttcctgt tcttctaggg cgcttccaga
     3601 taattcttcc tccggatcgc tgccaataat ctgctgacga agaaagtcac tcacatcttc
     3661 tgaatcaaca gtagaatctt ctgattgaga aatttcttca tccggaagat ttttactgat
     3721 aaacagttct aatccgtctc cttttggcaa aacttggaaa gtgacagctt cgcttcctcg
     3781 gaactcctct tcgatatcaa cttcttccaa aatactataa aagaaatttt cgatttcttt
     3841 gtgattgcca agtaaatcca aaaatgaaac gccccgttcc tctaaatctt catgaccaat
     3901 tagtacacgg atcgtatttt cattaatatg ttccatttcc attttgctac acctcacttt
     3961 gccacaatgt ttaatataga ttcattgtag cgaaatcagc ttaaatgtaa agaaaaaaaa
     4021 tctcgctgtt aagcgaattt aataaaacca gcggattttt caacctttca agctatctta
     4081 tttaactata acatttttgg cagacgaata ctatatagcc gacttttcag ctaattttcc
     4141 ctctctattt ttcgtgcaat catcatcttc tactaccttt ttatacatct aatcaagaat
     4201 actttttgta aaaacaaaaa aacttggaaa aactatcttt gtaatagtct tttccaagtt
     4261 tcgtattatc cttctataat ccagccatca attgtgcttg acgtaattct aattgtcgta
     4321 catcgcgcgg taggaaccga cgaatttcat cttcattaaa accaacttgc agacgtttat
     4381 catcaatcat gattggacgg cgaagcaatc caggattgtt ttgcacaagt tccaataatt
     4441 cttgtaacgg cagatcatct aaatccatgt tcagtttttg gaatactttg gaacgtgtcg
     4501 agatgatttc ttctgttccg tcttctgtca tttgtaaaat cgcttttaat tcagaactgt
     4561 tcaatggttc tgaaaaaata ttacgttcaa caaatggaat ctgatgttct tgcaaccacg
     4621 cacgagcctt tctgcaggaa gtacaacttg gggaagtata taatgttaac aacgtgcacc
     4681 actccttttc gtgataagaa tcactttttt gtaacagaag atcataataa tctcccatct
     4741 gtttctatta tacataatca acttttaaat agctaccttt ttttcataat ttttttaaaa
     4801 aaatgaaagt tatct
//
LOCUS       DACCVZ010000145         4588 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.149, whole genome shotgun sequence.
ACCESSION   DACCVZ010000145 DACCVZ010000000
VERSION     DACCVZ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.149"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(12..482)
                     /locus_tag="IVW63_002794"
     CDS             complement(12..482)
                     /locus_tag="IVW63_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HAP7861013.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(641..1099)
                     /locus_tag="IVW63_002795"
     CDS             complement(641..1099)
                     /locus_tag="IVW63_002795"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAP7861014.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1270..2415)
                     /locus_tag="IVW63_002796"
     CDS             complement(1270..2415)
                     /locus_tag="IVW63_002796"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HAP7861015.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2428..3345)
                     /locus_tag="IVW63_002797"
     CDS             complement(2428..3345)
                     /locus_tag="IVW63_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAP7861016.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3773..4336
                     /gene="efp"
                     /locus_tag="IVW63_002798"
     CDS             3773..4336
                     /gene="efp"
                     /locus_tag="IVW63_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAP7861017.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
BASE COUNT         1433 a          841 c          870 g         1444 t
ORIGIN      
        1 tttttattaa gttaaagaac ggattcaatt gcagcggtca ttttcaatgg agaagtttgt
       61 ggtgcaaatc gttcgattac tttgccattt ctatcaatca aaaatttagt aaaattccat
      121 tttattgctt tagtgacagt accaggagct tcatttttaa gataagtaaa aagaggatct
      181 gtattttctc catttacgtc aatcaattga tgcataggga aggtaacgcc ataagtggtt
      241 ttacaagctt ctgctgcttc agtcgctgaa tctagctctt gtttaaattg attggaagga
      301 aagcctaaga taaccagacc ttgtgtctga taagcttggt aaagttcttc taattgttta
      361 aattgaggtg ctagaccgca ttttgttgca gtgttaacaa tgattatcgg tttgcctgca
      421 tattttttca atgaatagac agtgccgtct tctaaagtag tttcaaaatt ataaatagac
      481 ataaagtttt ctcctttcta ttttatataa taaaaagagc gctaaactga aaactagcta
      541 tttgttttcc cgtttagaac tcttttcaga caataaatat ttaataaaat acgaagataa
      601 gatagctata ttgcttctca tctttacgtt cttttagaaa ctatgcttct acttcagacc
      661 attcatcgcg ttttgctaaa aattcacgag ccaaagcttg tgcaccttct agtgtatggc
      721 tggcagccca gccacattgt gtttcattgc ttgcaggtac ttcagtagct tcaagaacat
      781 ctttcattgt tgcttcaaga acatctaaaa tgtcttcgta gctttcatga ttcaatacag
      841 tcaagtaaaa gcctgtttgg catcccattg gagaccagtc tacgatgtaa tctgcgtgat
      901 tgcggattag ttcggcagtc aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt
      961 ctttatttgg ttgtttaaag cggacgtcgt atttaatgat gacatcgcca tgcgcacccg
     1021 tttttcgatc agctacacgt acataaggtg ctttgacttt tgtatggtca agattaaaac
     1081 tttcgacatt cattctcatt tgtaagactc ctatctgttt gttcattcgt tttgatgctt
     1141 ttcactaaag aattatttag tgaaatttac aaaaacgtct ttctacttga ttctaacact
     1201 tatcgtttcc aaggtgtagc aatctgaaat attttttaga tttttctgct aagtcgttta
     1261 ttgggacttc tagttcttga ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg
     1321 accatactca attcctacag aaagacggat caagccgtcc tttatgccag cctcttctcg
     1381 tttttctttt ggaatagacg catgagtcat gacagaagga atttccacta aactttctac
     1441 gccacctaaa ctttctgcta aagtaaatag ttggagtgat tcaacaaatg gaatagcaga
     1501 ttcttcattt tttaaagtaa aagaaatcat tccgctaaag ccgctcatct gctgcttagc
     1561 aactccatgg agttcatgat cgggtaatcc tggatagtag accttttcta ctgctggatg
     1621 agaaaataga aaatcagcta ccacaaaagc atttttttga tgttcctcca tacgaacact
     1681 tagtgtcttg attccgcgct gaagtaacca gctatcttgg ggaccaagta cggctccgat
     1741 agcattttgg taaaatccga tctgatcggc tagatcttta tggttagaag tcactaaacc
     1801 agctactaca tcgctgtgtc cgcctagata tttggtaccg ctatggacaa cgatatcaga
     1861 accgagatct aaaggtcttt gaaaataagg agtagcaaat gtattgtcag caataactat
     1921 caatccatgt tgatgagcca gagtggcact tttttctaaa tcagtaatct ttagaagcgg
     1981 attgctaggt gtttcaagat aaagtgcttt tgtattgggt ttgatggatt gttctatttt
     2041 atcaagatta ctcgtatcta tgatcgtgta ctcgagacca tttttagtaa gaactttgtc
     2101 aaatagacgg aatgttcctc catagacatc atctcctaat aagatatgat cgccagcttg
     2161 aaaaagagaa aaaacggcat gaatcccaga aagaccagaa gaaaaagcga atcctcgaac
     2221 accgccttcc aaatcagcaa tcagttcttc caatgcaaaa cgagtaggat taccagatct
     2281 tgaatattca tattgtttag gctggccgac gccatcttgc cgataagtgg atgtttgata
     2341 aataggtaca ctgacagctc ctgttgtggg atcttcactg atgcctccgt ggatcaattt
     2401 tgtttgaatg tgcatgtttc tttcctccta taagtaaatg ttttttgata aatagcggtc
     2461 tgctgcgtct ggaaaaatcg taacgacacg atgaccaggt ggtaaacgac gaatttctct
     2521 taatgctgct gcaaaagccg caccactcga acttccaact aatagtcctt gttctcgtgc
     2581 taactgccta gtatagttaa acccttctac atcagagatt gtctcgatct gattgattga
     2641 aaggggagaa agaaacggcg gaatgaattc tacaccgata ccctcaattt cgtgaggggc
     2701 tggatcacca ccatttaaca cagagccctc tggttctaca ccgattattc gaatgtcggg
     2761 atatttttct ttcaaaaagg tagaagttcc agcaaaggtt ccaccactcc caattcctgc
     2821 tacaaaacta tggatatttt ctttgatttc atgaaagatt tctggcccta acgtatgata
     2881 gtaagcagca ggattatctt tattttcaaa ttgaagaggc agatagctgt ttgatatctc
     2941 ctctgcaagt tttttacttt tgctgatggc accgatgatt ccttgctcac taggagaatg
     3001 gatgatcttt gctcccaatg ctttcatcaa ttgttgtttt tctaagctaa acttctctgg
     3061 aacaacaaaa accgttctta atttgtatgt gagtgcggcc agagcgatcc caattcctgt
     3121 atttccggca gttggttcga tgatcgtcgt tttttcattg atttttcctt gggcaaatcc
     3181 ttctttgatc aaataactgc ccaatctatc tttgatactt cctccaggat ttaaatattc
     3241 tagttttgca taaatagcag aacctttagg catagaatag tgctgattgt caaagcgata
     3301 aagcggtgtg gaaccaatag cttctgtaat tgtcgagata atcatgtggg cctcctaaaa
     3361 aaagataata aaaaaaggag ctgactatta aatcagctcc ttgaaagaca tagagaaaaa
     3421 ttgagtagat aaaaagataa gttacctggt actcattcta tgaagggcaa ttaatagaca
     3481 tgacaaatag tatgctgctt ttatgcacca tacaacagca acgattcaat tgtttttggt
     3541 tgctgactgt catgtgtatc cctccaagta aaatttttat taacgatagc atgaaaaaaa
     3601 ataaaagtca aaggcttgaa agaaaaaaat atttcgatag catcgtttac ccgtgtttat
     3661 ttttctgaca aataggcatg agaccttaaa agatagagaa tactctagtt ttctggccgg
     3721 ttgtctgata caataaagtt gattatgata aagaaaagaa ggagcaaaaa taatgatctc
     3781 agcaagtgat ttaagagccg gtatgacttt cgtacaagac ggcaaactga ttaaagttct
     3841 ggatgcaagc caccataaac ctggtaaagg aaatacagtt atgcgtatga aactgaaaga
     3901 tgtccgttca ggtgcaacat acgacacaac gttcagacca gaagaaaaat ttgaaaaagc
     3961 acatatcgac acaaaacctg tacaatattt gtacacgatg gatgatacag ctttcttcat
     4021 ggatttggaa acatatgagc aatatgaaat tcctgtagaa acagtagaag aagaaatgaa
     4081 atatatccta gaaaacatgg aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt
     4141 tcaattacca acaactgtcg tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc
     4201 aacagtcact ggttcaggta agccagcgac aatggaaact ggcttagtag tcaatgttcc
     4261 tgacttcatc gaaacagatg aattgttgga aatcaataca gcagaaggtt cttatgtaaa
     4321 acgtgcgtca aaataattcg ctaacggatt gataagaatt tgaaaacaga gcttgacctc
     4381 ttgaaaggca gatcatcgga tctgcctttc aagaggtttt ttgtggaatc agcaaattga
     4441 aaaataaaaa agtatttgat tttatttata ttttgaaaga tgaatggcaa aagctagaga
     4501 aagaaaaaac tgcacttatt tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc
     4561 gaactattcc gaactatatt gaagcgaa
//
LOCUS       DACCVZ010000146         4587 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.150, whole genome shotgun sequence.
ACCESSION   DACCVZ010000146 DACCVZ010000000
VERSION     DACCVZ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.150"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            186..2855
                     /locus_tag="IVW63_002799"
     CDS             186..2855
                     /locus_tag="IVW63_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAP7861018.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3566)
                     /locus_tag="IVW63_002800"
     CDS             complement(2946..3566)
                     /locus_tag="IVW63_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP7861019.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3680..4219
                     /locus_tag="IVW63_002801"
     CDS             3680..4219
                     /locus_tag="IVW63_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861020.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4216..4554
                     /locus_tag="IVW63_002802"
     CDS             4216..4554
                     /locus_tag="IVW63_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HAP7861021.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1419 a          790 c          860 g         1518 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 tacattttta aaaggagatg tataatcgag atttagaaag cgttttcctc aaaatttaat
     3661 gaattaggaa gtgattacta tgaaaaaatt atttagcgca ctttttattc tgttatttgg
     3721 ctttattggt attgggactt ctggaaatat agttaaagct agcacgatgg ttgaacaaac
     3781 aagtgaaatg gcaaaaactt ttagtcaatt aacaccagaa gaacaaagtt acttcaaatc
     3841 caaaggattt agtgataaag atacttttta cactcaaaag atagagcctc aagatccgaa
     3901 aacacgtttt tctgcaaatg tattgcggtt aaccgcatct actaaaaaaa ttactaatac
     3961 gcaggggcgg acagaatata ttataacaag tcccaattcg gcgatgtatc gtatttctac
     4021 acgcttgagt ttaggtagtg caaaatcata tactcaaaca gtaaatctag ctaattctta
     4081 tggttatggt ggaggaatgt attttacatt tactgggaaa agacaatatt acagtgtaaa
     4141 attagctatg caagtttata atacatttgg tgtagggtca gtctcttgca ctgcgggagg
     4201 attgacaata ggaaaatgat aatttcttac tatgtcttaa atagaagtga tgatgaagga
     4261 ctcttcgttt ttcaatcatt acatgaggat acgatgctaa aagagtttta taatcggatt
     4321 aagaataaac agatagaaac aaatttatat tttttaagtg actctatctt gccttttatt
     4381 agcaacccta aaattcttaa cttgttgcag acaaaagatt tgaaaagttt accgattatt
     4441 gtcattgatg aggaaattgt aaaatatggc gcttatctaa gcgtagaaga attagaaaaa
     4501 ttaactaaca ttggaatgag tattcaggag gataatgggg tacatggaac atagaatgaa
     4561 tatgcacagt tgagaacgga atttgac
//
LOCUS       DACCVZ010000147         4486 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.151, whole genome shotgun sequence.
ACCESSION   DACCVZ010000147 DACCVZ010000000
VERSION     DACCVZ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.151"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(28..963)
                     /gene="murB"
                     /locus_tag="IVW63_002803"
     CDS             complement(28..963)
                     /gene="murB"
                     /locus_tag="IVW63_002803"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAP7861022.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1036..1956)
                     /locus_tag="IVW63_002804"
     CDS             complement(1036..1956)
                     /locus_tag="IVW63_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP7861023.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2069..2821
                     /gene="xth"
                     /locus_tag="IVW63_002805"
     CDS             2069..2821
                     /gene="xth"
                     /locus_tag="IVW63_002805"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAP7861024.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            3685..4218
                     /locus_tag="IVW63_002806"
     CDS             3685..4218
                     /locus_tag="IVW63_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAP7861025.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT         1323 a          878 c          795 g         1490 t
ORIGIN      
        1 tttacttatt ttaagttcca ttacttatta attggctaaa cttctgcttg tttctgatat
       61 tgcttgtttt tctccaatga tccgcacttc tgtttctaaa gacacatcaa atttttcttt
      121 gattacttct tggatgtgcg caatcaattc aatataatct gtcgctgtcg catgatcgat
      181 attgacgatg aatccagcat gtttttcaga gacttgtgca ccgccccatt tcaggccttg
      241 caatcctgct tgttggatca gctgacctgt atagtgtcct actgggcgct taaagacact
      301 tccgcatgaa gggtattcta atggctgttt tgattgacgc aattcggtca actcatccat
      361 tcttgctttg attgcttcat aatcccctgt ttgcaaactg aatcgagctt ccaatacgat
      421 agcacgtaat tcttggactt tactgtgacg ataagaaaat accatttcgt cttttgtcaa
      481 agttttcaat gttccatctt caagcaaaag atccacttca gcaaaaacat ctttgatctc
      541 tccgccatac gcacctgcat tcatataaac cgctccaccg acacttcccg ggatgccgca
      601 agcaaattca aatccagtca atgattctgc caaagctgca taagtcgtat caatcagtga
      661 ggcacctgct tccgcaatga ccatcgttcc tttgacatga atctgtttca tttcagtcag
      721 catgatgact acaccgcgaa tcccgccatc ttgaacgatc agattgcttg catttcctaa
      781 taccatccaa ggtatatcat ggattcggca ataatcgatg atttgcttta cttcttcttg
      841 ttttttcggg aatgcaagga catcagctgg tccacctgtt ttcgtaaacg tatagttcat
      901 caatggttca tcaaacaata tagtaatcgt ggctaagctt tcaactattt cttctttatt
      961 cactgaggat tttcctttct tttctcaaac gtcctcatta ttctatcacg cttaatacaa
     1021 tcttgccagt cttgttcaaa gttgatgacg gtagtgatct ttaagcactt cctcacataa
     1081 ttcatgactt cttacaactt ctttttgttt aagcaattct gtttccgatt tacctaaacg
     1141 gatctgagaa aagaaggcct ctaccattgg ctcaaacccg cgtttgacta gcgtgtttgt
     1201 ccagtcgcca aattctttca ctttttttcc atcagcatct tgaatgacaa gctgggtcag
     1261 atcgtttact tcataagtac catttttact tgttacttga tatttttcta tattagcgcc
     1321 acttgctaaa tccatcgtta aaatagccgt ttgattttgt gtttctaatt gtaaaatggc
     1381 atattccaaa aattcctttg tttctcttat ctggtatttt gttctcaaaa tgggttcatc
     1441 taataaatac acagctgtat caataagatg taaaaacaaa tcataaagga cgaactctgt
     1501 cgtttctttt gccgctattc gatttttttg caggtggatc aaccgcttat ctgggatacg
     1561 tttcaattct tctaccatag gagcaaagcg ccggttgaaa ccgatcatca aaattatttg
     1621 gttcttatca gctaattctt gcaattcacg aacttcattt agatggacac tcagtggttt
     1681 gtcaatataa acatggatac cattttctag acattttttg gctaattcat aatgtacttt
     1741 tgttgctgcg tggatcatac atgcttcgat tttttcttct aaaagctcat cgatcgtttc
     1801 atatagatgt tggaacccgt actctttttg aattctttct tttgtttctt tatttcttgt
     1861 tgcaaaataa aaatcaagtg ttccttgttt tttcgcataa gttggtaaat atgctttttc
     1921 tgcgatattc cctacaccga ttacaccaat cttcatctac tttcctcctg gatcatttag
     1981 ttactttcat cttacaccat tttttactaa aatgaggtac aatagtatcg caaaggtaag
     2041 gaaattaatt cgaaggagtg tgcttttatt gaaatttatc tcttggaacg taaacgggct
     2101 tcgtgccatc gtaaataaaa attttttaga agtttttcat gagttagacg ccgatttttt
     2161 ctgtctgcag gaaacgaaac tccaagcagg acaaattgat ttagatcttc caggttatta
     2221 tcaatattgg aattacgcgg aacgaaaagg ctattccggc acagcgattt ttgctaaaaa
     2281 accagcattg aatgccactt acggaatggg tatcgatatc catgatacag aaggccgtct
     2341 gattactttg gaatattccg atttctttct tgtaacctgt tacacgccaa attctcaaag
     2401 cgaattaaaa cgtttagatt accgattaga atgggaagaa gccttttata attatttgga
     2461 aaatctaaaa aaacaaaaac cagtcatcgt gtgtggggat ctaaatgtcg ctcatcaaaa
     2521 gattgatttg aaaaactgga aaacgaatca aaaaaatgct ggattcactc cagaagaaag
     2581 agcggctctt tctcgactgt tggataacgg gtttatcgat acattccgtt atttttatcc
     2641 aacccaggaa ggtgtctact cttggtggaa ctaccgattc aattcaagga aaaacaatgc
     2701 tggttggcgg atcgattact ttttgacgag caaagattta gagccaggac tagctgatgc
     2761 aaagatccat acggacatta tgggcagtga tcattgtcca gtagaattag atttgaaata
     2821 aagaggttgt gaaaaagtcg tttagtttcg agtattaaga aaaattttgt gaaaatggct
     2881 ttccacattt tgcataaatt tggcataata ccgagaaact ggcttttgaa cactgtttat
     2941 cgagagattg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagt
     3001 tcctcatatt tttcgtttgg ttgggcttat taccgcagat acaagctttt gaacaccgtt
     3061 tattaagagg ttgtgaaaaa gctgcactgc atcaagtaat aagaacagcc aaacaaaaat
     3121 agttcctcat atttttcgtt tggttgggct tattaccgca gatgcaagct tttgaacacc
     3181 gtttattaag aggttgtgaa aaagctgcac tgcatcaagt aataagaaca gccaaacaaa
     3241 aatagttcct catatttttc gtttggttgg acttattacc gcagatgcaa gcttttgaac
     3301 accgtttatt gagaagttgt gaaatcagcg tcctgacctg agtattagag aaacaaatgg
     3361 caaaatagtt cctcatattt tgctattttt tgagctaata ccgagggtca gctgattgaa
     3421 caccgtttag tggagaagtt gtgaaaaagt cgcctacttt cgagtcgtaa gaaatttttt
     3481 tgaaaatggt tcctcacaac tttgcataaa tttgacttaa taccgagaag tcatgatccc
     3541 catctaactc caaatcacaa ggaatgagtt caaaaactag cttttctcaa caaatattac
     3601 ataaaaaatt ctatgttttt tgttaaattt atttgctttt ttcaaaagta tgttacagta
     3661 atttcccaag gaggttttac agaaatgaat tttgttgcca tggattttga aactgccaat
     3721 catcagcctt atagtgcttg ttctcttgcg ctagtcatgg taaaaaatag ccagatcgtt
     3781 gatgaattct atacattgat acagcctgag actccttttt tctggcgaaa tgtccaaatt
     3841 cacggaatcc atcaagaaga cgtacgcaat gcgccgaaat tcccagaagt ctggcaaact
     3901 atccaaccat attttcaaaa aaatcgttta gtcgttgcac ataatgctgc ttttgataca
     3961 aaggtcttag cgggatgctt agattattat catcttgaac agcctaatta tctttcttta
     4021 tgtacagtga aaagtagccg tcgcctgttt cctgaatttc caaatcatcg attgaacact
     4081 gtgtgcgaaa atttgaacat ccaattagat catcaccatg atgcattgga agatagtcgt
     4141 gcatgtgcgg aaatcctgct ttatcaagaa aaaaaattcg ggacagatcc attgaaaaaa
     4201 cttgtgacta taaagtaaaa gaatacttat gaaacacaca aagaggtcgt gagcctgccg
     4261 tttcactccg agtcacaagg agcaatttca aaaaatagct tctcatgttt attaaatatt
     4321 gtgactggtg accgaggagc tggcaggaga acaccgttta ttggagaggt tgtgaaaaag
     4381 ctgttctgca tcaagtaata agaacagcca aacaaaaata gcttctcata tttttcattt
     4441 ggttggactt attaccgcag atgcaagctt ttggacaccg tttacc
//
LOCUS       DACCVZ010000148         4453 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.152, whole genome shotgun sequence.
ACCESSION   DACCVZ010000148 DACCVZ010000000
VERSION     DACCVZ010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.152"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(456..881)
                     /locus_tag="IVW63_002807"
     CDS             complement(456..881)
                     /locus_tag="IVW63_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861026.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            1255..2226
                     /locus_tag="IVW63_002808"
     CDS             1255..2226
                     /locus_tag="IVW63_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP7861027.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            2258..3655
                     /locus_tag="IVW63_002809"
     CDS             2258..3655
                     /locus_tag="IVW63_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP7861028.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            3814..4437
                     /locus_tag="IVW63_002810"
     CDS             3814..4437
                     /locus_tag="IVW63_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861029.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
BASE COUNT         1557 a          715 c          909 g         1272 t
ORIGIN      
        1 tactacgtga tgtagaataa gcctttctat cgtttggtta ttttatattc aaatatttga
       61 aataaataaa tctttactct ttgatttgta aactgaaatg atccactgtt tgttttactg
      121 atgaagcttg atcaaaggaa gaagctgagt ttgaagttca taaaaatcag ccatagtgag
      181 ttttgcttgg atttgtttat cttcttctac tttttacata attttgaaca ggataagatt
      241 caaatgtttt aaatgaatct ttgactagtt tgtgacagtt gtcgcatatg ctcaagcttc
      301 cttggtcatt aaattctgta tggatatttt tgttgttatt acatgtacaa taatcaggac
      361 tatcgatcat ccatttcgtc tcctttacaa tcatcttgct tctttactat agcagaaaag
      421 aaggggagaa acaaaagaag atccaacaga cggcactata gactgtagat gttgccatcc
      481 tcatccttca aacggtaatt accgattttt gtaaatatga ctgttgtttc ttttttattt
      541 tcttttcctg aaataatata ttcgtcatct ttggtagtga tcttgatatc tgtcagcact
      601 gttttttctt cagatgattc agaagaatca gttccttgtg tctgatacgt gcgtgtccat
      661 tccatttttt tatctgtaaa tgtcaactgt cccgcggata aatccatatc tttacgtact
      721 tttagcgtat atacactgtt ggtggtatct gctttttccg cttttaagac agaagaatcg
      781 gttgtttcgt ccgaggattg gtcagagccg ccaaacaaat cacagccagt caatgtcaaa
      841 agtcccgcag acaaaataaa tagtacgatt aatttcttca aaatacttcc cccatttgat
      901 aggataaaga aattatacca ttggaatgta aaacttcaaa cggatggaag agaaaaacgc
      961 acaaaacacc cacaaataga gtaaatttta gaataaaatt ttaaaaaggc aaaaaatccg
     1021 ccactttcag aaagcgtttt aaaaaagtgt tgcaatcttt taaaaaaatg ctatattaaa
     1081 aatgaaccgg ttcaaatact tgtttaagta taattaatag tgagaggaag ttgctctact
     1141 gaagacttta gttatatgga tattgatgac aagcaacact atgcaaagaa tgcggtcatc
     1201 ataatcgaac aacaagaaag agaaatcaaa tgtaactggc aggagtgaga atgtatggca
     1261 tcgatccgtg atgtggctaa gatggctggt gtttcagtgg gaacagtttc ccgttacttg
     1321 aatggtcagc aactgaagga aaagaacatg aaaaaaatag cagaagcgat ttcagcgttg
     1381 gactataaag aaaacatcat tgctaaaggg ttgaagaata atcgaagctt ctctattgga
     1441 cttttgataa acgggatttc cagccgtttt gggtcggaag ttgtctcagg gatcgaaaga
     1501 gtagctgaag aaaatgggta tagcttatta ttaagcgggt ttgccgatca gccagaaaaa
     1561 attgaacaaa aaattgaata cctgatgaag catgtgatcg atgggctgat tgtcttctta
     1621 tccgaagaag agtggtctgg atttgaaatg ctcacaaaaa tgagtattcc agttatcgca
     1681 ttgaattgtc cagaaggacc agcaggtatt gatacaatat tagtgaatga tcgagaaagt
     1741 gtagcaaaag tgatcgctca tcatggtgaa caaggacata aaaaaatcgg atttattgct
     1801 gccactcaaa cagactacgt agcaagagaa cgtttagcag gagccaaaga agcggtccaa
     1861 aatgatccat cgatccaatt agaggtcttt acaggagact attctagaaa aagcggctat
     1921 tacggggcaa aagcattatt agaaaaaggg gcaactgcta tttttgtcag caattacaat
     1981 atgtcgattg gtgccatcga atgtttcaat caagaaggtg tcagaatcgg gaaggatatt
     2041 gcgttcagtc actatgatta tttagataaa aacgatctga gtatccttcc gaaaatcacg
     2101 atcacgccac caacagataa aatcggggaa cgagcagcag aacagctgtt aaaacgaatc
     2161 aaaaaagaag aggaagaaaa tgaaaaagtg attgtgatgg aaaatatcat acatggaatc
     2221 aactaaaacg aactaaaaaa gaaaaagagg tgctttgatg aaaaaatatc aatttccagc
     2281 aaatttttgg tggggttctg cagcaagtgg cccacaaaca gaaggaagga tttcaggcga
     2341 tggaaaagga gagaacattt ttgattattg gtacaaaaaa gaaccgcaaa agttctttga
     2401 tcaagtagga cctgaaaaaa cctcgcaagt ttatacgaag tatcaagagg atgtacagtt
     2461 gatgaaacag actgggcata attcatttcg aacatctatc caatggagcc gtttgatacc
     2521 tgatgaatct ggaacaatca acgaagaagc cgttcgtttc tatcatcgtt attttgatga
     2581 gttgattgaa aacggtatcg aaccctttgt gaatctgtat catttcgata tgccgatgta
     2641 tctgcaagaa aaaggcggat ggttgaaccg agaaacggtt gaagcctatg aaaaatatgc
     2701 caaaagttgt tttgaattgt ttggttcgaa agtaaaaaaa tggtttactc ataatgaacc
     2761 aatcgttcca gtcgaagcag gttatttata tcgatggcat tatccagaag agtcagatat
     2821 gaaaaaagcg atccaagttg gctatcatga agcgttggct tcagcgttag ccatcaaatc
     2881 ttaccatgaa atggagcaag gtggtgttat tggtatcatc ttgaatctga caccaagcta
     2941 tccaagagac gaatcaaacc ctgaagatgt taaagcagcg caaatagcag atgcgttctt
     3001 caatcgttca ttccttgatc cagctgtaaa aggcgagttt ccaagtgaat tgattgagat
     3061 agtaaaagaa cttgatctca tgcctgtgat ccatgcagag gatttgacgg ttatcaaaga
     3121 aaatacagta gatcttttag gtatcaatta ttaccagcca cgccgggtaa aagcaaaaga
     3181 aacaccaatc gatactaaaa acggtccaat gcctgaggat tatttcgaca attatgaaat
     3241 gcctggtcgt aaaatgaatc cttatcgcgg atgggagatc tatgaacaag gaatctatga
     3301 tattttgatc aatgtacgag atcattatgg aaatatcgac tgctttattt ctgaaaacgg
     3361 tatgggtgta gaaaacgaag cacgatttat caaagaagat ggcatgatcc acgatgatta
     3421 tcggatcgaa tttgtccaat ctcatctgaa atatgtccat caagccattc aagaaggtgc
     3481 caattgttta ggctatcata tgtggacatg tatggataac tggtcgtgga ccaatgcata
     3541 taagaatcga tatggcttta tttcagtaga cttagcacaa gatggaaaaa gaacaatcaa
     3601 aaaatcgggt cattggttca aagacgtatc agataaaaac ggatttgagg cttaagaaag
     3661 aatagttgag agcaaatgcg tgaaattctc cattcttacc attttgtgaa aaagaagttc
     3721 aattatttac gatctttttc aacttttttg tctttctatt tcattttttg tatataatag
     3781 aatagtcaaa attaaatagg agtggaggaa agcatgagga aaaaaagacc gtttcttctc
     3841 ttttggttat tcggtttttt cttactgctt attttatccg cagcattttc aggaaaaatg
     3901 acagcagatc ttgctcagaa agaaacagaa aaaatcgtag caagcaaaga atcagtagat
     3961 aatttcaaaa aagaattctc aacttattgg tgggcggagt ataaaataac tgccaattac
     4021 gaaaaaggcg aattggacat ttatttgcca aaaggaaaag aagaaaatca atttattaat
     4081 atcgatgacg tacttagtgc gatttctctc agacaatatc aatttaaaga caagcatttg
     4141 accgttttgc ttttgactca tgatggcgac aaagtagccc gtttgaaaaa tggaaaagtg
     4201 atcaccgctt attctgaaaa agtagacaaa aaagtggtcg ccgatcgttt agcggaatgg
     4261 aaaaagacaa atgaacaagt caagaaaaca actgtctctt ctcaaaaaaa cgagtcgaca
     4321 ggaacaagtc cttcagattc tggcagtgga caaacgataa cgggaagtga agaaaatcaa
     4381 gcctcaatta ttacgaatga gtcatcacaa ggacaatatc aatcctatgg acaatgaaaa
     4441 acagaggttg tga
//
LOCUS       DACCVZ010000149         4369 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.153, whole genome shotgun sequence.
ACCESSION   DACCVZ010000149 DACCVZ010000000
VERSION     DACCVZ010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4369
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.153"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..602
                     /locus_tag="IVW63_002811"
     CDS             <1..602
                     /locus_tag="IVW63_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAP7861030.1"
                     /translation="IDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFRAIINR
                     CLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGMFAPDE
                     KFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKWFDERD
                     IDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            595..2022
                     /locus_tag="IVW63_002812"
     CDS             595..2022
                     /locus_tag="IVW63_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAP7861031.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            2024..3094
                     /locus_tag="IVW63_002813"
     CDS             2024..3094
                     /locus_tag="IVW63_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861032.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            3081..>4369
                     /locus_tag="IVW63_002814"
     CDS             3081..>4369
                     /locus_tag="IVW63_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAP7861033.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVS"
BASE COUNT         1513 a          530 c          682 g         1644 t
ORIGIN      
        1 gaatagatct agatcaaatt aaacataaag aattttatta taaacatata gatgtatatc
       61 aaaaacatga ttatcctaga attaatagga ataacacaac tgcatttaaa atttttagag
      121 ctataattaa tcgttgtctg aggatgatta aacttccccc aaaaattaga caccataaat
      181 ttgatttgta tcatggttct caatggtggg ctttgtcgaa agaatgccta acagaattaa
      241 tacaaatgta tgaacaaaat caacaagact acctgaattt taaaataggt atgtttgccc
      301 cagatgaaaa attttttcat acactttttt ttaattcctc gttcaaaaat aaaaatgtta
      361 ttggaggacc agatttacca cttgaattga aaaatattga agaaactact ttacaaactt
      421 cgaaattagc aaatattcat attattgatc cttccatgaa caaatggttt gatgaaaggg
      481 atatagatca aataaaagaa agtgaaaaat tatttgtaag aaaagttaaa tcggattact
      541 ctgataaact attaaataga attgataaag aaattttgaa agttggaaat atagatgaat
      601 agaatagtac ctgttttaga gaagagttta ttaagtcgag atgcgtttcg agtaataaat
      661 ttaatcattt gtctgcttta ttttatgcct agtactttta atgtaactaa tatcccgatg
      721 aaaatagctt ttgcttgggg tggaattata gttttgtatg aggtttttat aaagaaaaat
      781 ttttttaaaa tgcgtttttc ttggctactg attggagcaa tgattagttt tatcttaact
      841 ataatcatta acagagaaaa ttttttaatt ccatctattt ataattttgg atatttgctg
      901 attactttga tagtaatttt tcctgcagac ttttcacaaa gtgaagagga aaaaaagaaa
      961 aaaatggtgt attttaataa tgttttcatt atcataattt ttttagctgc gctaatatct
     1021 atctatcaat ttattttttt gatttcttat catgtcccaa caggaacgcc aggattactt
     1081 gcaagacaag gttttattga acatcggtta tttggtgtct atacaagtcc aaatgttgga
     1141 gctatgtttg gatatacttc tattatttta agtttaatta gtgtattaat ttcaaaaata
     1201 acaaaaacga ttcgtgtttt ttatatgatg aattttatcg tacaaatatt ttatattaca
     1261 ctttcttcgt ctagaggtgc ccaggtagta atttgttctt ttttagtatt atttcttttg
     1321 ttgtttgcca attcaaaatt tagaaagagc attagagaag tactacctgt aaaaatcaaa
     1381 tggatggtaa gcatattatt agttctattg gtatattttt cttttggtac taattatgct
     1441 aaggattttt tagcaacaat tcctgtatcg attgatagaa aagtagaagt tatagagtca
     1501 aatgaatcag ataaaactcc acttccagaa aaagaagtaa tattacagca ttctagtgat
     1561 aactccgaaa tttcagctgg tcgttttacg atttggaaag ctgcgcttaa agttataaga
     1621 ccaactttgt tatttggtta tggagagacc gatttctatg ggaatagcga tgcaaaattt
     1681 ttgaaaaaag tagatcttga tactacagat gtgaatgaac taaaaagagc acatggaaac
     1741 atgcataatg gatttcttca agtacttgta tcaagtggta taattgcttt tatatgtatc
     1801 tatgctttct atgtgttaaa tatctttagt ttactcaaaa cattttttag aagtaaagtg
     1861 aattatgcgt ttcttggtat tgttttaatt tttatactat ctatttttat agatgaaatg
     1921 gtggaggctc atgtactttt caataagcgc gatgtcattt caattgtttt ctggtattat
     1981 ttgggaagca tttcttactt gtatttaaaa aaggagaatt aatatgaaga cagctttcat
     2041 tgcttggact cctttacatt tgattaatat attaaatgtt tatcaaaatt tttaccgaga
     2101 atcaaaagga gatttattta tttattctga atttgaaaac gctagaagat atagtgagcg
     2161 tataaaagaa ttagggctat ttaatgatgt tgtttttgtg aatcaccgga aaatcggttc
     2221 ttcctttaaa cgtaaaatta acttgttaac taaccataat caatttttct cggatgattt
     2281 atccgtttat gatgaaattt ttatacaggg ggaaaattat ttcacaaaaa tacttttctc
     2341 caatgtttac aaaaaaaatc cagatgtaaa actaaattat atagaagatg gtttgggtac
     2401 ttatttgaag aagagtatat tttcaacaag taaaaacgtt caaagagttt ttaaaatatt
     2461 aaataaaaat agcatcttca aaaaaaaaat tgacgattat tttgtctatt gtccggaatt
     2521 gttactttat gatgtaaaaa atataaaaaa aattcccaaa atagatgaaa acagtaaatt
     2581 gatgaaaaac atacaatcaa tctttgggat agaagaagtt tttgtcggag ataaatgtat
     2641 cttttttgat caacctttat tatctgatgg ttatggcata gatgaaacag atattttcgc
     2701 taaagtaaat agtatatttt ctggaaaaaa agaaacttta attaagcttc atcctagagc
     2761 aaggacaaat cgttatggtg aaaaaaacat attgaattcc agtttaccgt ttgaagtctt
     2821 gctacttgaa aatgacttct cttcaacact tttgattagt cctatatcta caatttcttt
     2881 ttcaccatct atgatgtttg aaaagacgat caactctatt atgttggcta aattaatttt
     2941 aaatgaatat acagcattat ctgaagataa aaaagaaaca ttgacaaata ttgttctttt
     3001 ctgtgaacat tataaccgtc tatcagaaga aaaaatttta ctcccagaaa actgggcaga
     3061 attaagaaag ttggtagagt atgggattat ttaacacact ttccaagtca aaattagtta
     3121 agtccagttt ctggtatact atagggaatt tttttattaa gggaatttca ttcataacta
     3181 ttcctatttt tgtaaatatt actactcaag cagaatatgg tttgattaat aatttcactt
     3241 catttgtatc aattttttcg attcttgttg ggctaagcct aaattcggca attaataatg
     3301 caagttttga ctataaagat gacataaatg aatttatgtc atcggtactt tctctagcta
     3361 cactttcgtt aattgtgttc ttattaatag ggaacatata ttttttgttt tcaaatgctt
     3421 tttttgatat gaaccaactt gtatttaatt tgatgttatt acaaagtttt gctagttttg
     3481 taattagtta tatccagtct tattttacga ttaactttaa ccattttaaa tatttgattt
     3541 tatcttttat atctactttt ttgaatattg caatctctgt agctttgatg cagacattat
     3601 attttgatga taaatatgtt ggcagagtag tcggcggaac actgtcattt gtgttgatag
     3661 gtttagtaat ttatttaaga ataatgataa agggtgctca tttttttgat aaaaaacagt
     3721 ggagatacgc tttaaaaatc tctttgccgc taatcccaca ttccttagca aatatagttt
     3781 tagcacaatt cgatagaatt atgattaatt cttatttagg tcctgctgcg gggggaatat
     3841 attcctacat tagtaacata ggtattattc taagcgtaat atggatgtct actaataacg
     3901 cctgggttcc atggttctat ggtgagatga gtaaaaataa tgaaaaaaaa gtgaagaaag
     3961 ttagtaacta ttatttagta gtctttactt tgattacgat gattgtaatg gtagtttcga
     4021 ttgatttagc aaaatttatg gctccgaaag actattattc tgggttatct ttagtggttc
     4081 cgataacctt aggctatttc tttcagtttt tatatagttt accagttaat gctgaatttt
     4141 atgagaaaaa aacatcgttt attgcgattg gtacagtagc aagtgctata gttaatatac
     4201 tattaaacat gattttcata cctaggttag gaataattgc tgctggatac acaaccgtat
     4261 ttacgtattt tttacttttt atttttcatt ataatatcgc taaaaaaatt acgaataaac
     4321 aattatttga cacaaaaaaa atatgtatca taataatttt tgtatcaat
//
LOCUS       DACCVZ010000150         4310 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.154, whole genome shotgun sequence.
ACCESSION   DACCVZ010000150 DACCVZ010000000
VERSION     DACCVZ010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.154"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(665..958)
                     /locus_tag="IVW63_002815"
     CDS             complement(665..958)
                     /locus_tag="IVW63_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HAP7861034.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(1361..2539)
                     /locus_tag="IVW63_002816"
     CDS             complement(1361..2539)
                     /locus_tag="IVW63_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7861035.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(2643..2957)
                     /locus_tag="IVW63_002817"
     CDS             complement(2643..2957)
                     /locus_tag="IVW63_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7861036.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            3064..3279
                     /locus_tag="IVW63_002818"
     CDS             3064..3279
                     /locus_tag="IVW63_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861037.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(3579..3821)
                     /locus_tag="IVW63_002819"
     CDS             complement(3579..3821)
                     /locus_tag="IVW63_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7861038.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(3808..4236)
                     /locus_tag="IVW63_002820"
     CDS             complement(3808..4236)
                     /locus_tag="IVW63_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP7861039.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFLI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         1364 a          824 c          650 g         1472 t
ORIGIN      
        1 tacgattatt gaaaaaaaaa gataaaactt gattaattga agtattgctt aaatttggaa
       61 gctatgaggg aagaataaaa gagttaggac gggattatct actatttttc tttgttttaa
      121 atatttgtta tctttgaaca taaaagagaa atgtgtcgac tgcagtgttg tgtccctcat
      181 cacgaataaa cggtgttcaa ttagctgatc ttgtattcac ttaaaaaatg gtaaagtacg
      241 agttgctatt ccccattttc aattttctaa cgctcaggac aaaatactgt tttcacaacc
      301 tcattggaat aaaagcatat atattgtttc aagaacgaaa tcttgttatc tttttaaagg
      361 gcatctgtcc aaaatctaat tttaggaggt acgttttggt atttattcgt acaaataaaa
      421 gagaattatc tttattcatg taacgcatcc aattgatttt ttcatgtacg ctcctggaac
      481 gattttactg acgattgctt atttaactgc gaatcgctca ttagctttta tcatagctat
      541 ccatattttg aataacgttc ttggctttgt attatagata cagatgacaa aaaaagttca
      601 agtatgcggt gtagaaccaa tatcgcatac ttgaactttt ttcaatgagt ataaattaaa
      661 acttctaatt ttcaattccc atcatctgat atgcccgacc gtctgaactt cttttgaaaa
      721 agccaaatgt gattagataa cgtctttgtt cgacataatc gccactagaa aatacgttca
      781 gcagtatcga attaacctct gtttctgtat aagtcactcc atggtcaaag cgtttcaaga
      841 cttctttcaa taggatgtat ttcttttttg ttgaacttgg tacttgtttt acttttccat
      901 cattcatgaa tgtgtctaaa actttcatct tttcttgctc cgtataagta taaaccatct
      961 tctttctcct tttgattcta agaatactcc atttatgtta gaatattctg gattttttat
     1021 taaagcggtt actcttaaga aagatattat catagtgctc ttttttttac tactacttat
     1081 aggtagattt attctaatcc attattctcc cctaccaata attaaagaaa aaactggatc
     1141 agggtgttca aattacatgc taagaaaaaa gaacccttga ataccaaggg ttctttctca
     1201 gtctgataac aatgattaac gacggatttc tttgatactt gtgaaaagtc gttaaagtat
     1261 tgatataaaa ggatttttat tacctctgac tacatattga ctaatttgtt aaaaaatcgt
     1321 ttttcaagaa tcctgtaata ccagtgcttt caccgttttt ttaactctct aaagaactaa
     1381 aagcaatcag aggttttacc ttttcatttg acgttaagtg gcgataaatt ttcgaagttg
     1441 tttggtcagt atggcctaag cgatctttca agacttccca gctacagtgt tccgctacta
     1501 agcttgccat tgtatgacga gctaaatgag tatgaaatgg cttattaatt cctgagcgat
     1561 tcacgcaccg tttgacgtga tcatttacat actctcgacg ataaggaaca ccacgtttac
     1621 tagaatcaag atacacaaac aaatatgttt cttctataat aaacctgtaa tgttgcctca
     1681 tctcacccaa agccttaatc aactgttgta gcttttccat aactagagga gttactagaa
     1741 ctcgtctagc agaactaact gtcttagtag tttcaattcg aaaatcctta ctcttacctt
     1801 taactgccgt ttgcttatag aacagaattt catttctttt gaaatctata tctccaggct
     1861 gtagagcaag cgcctcgctg actcggcagc cagtgtaaaa tagaacatgg aaaagtacag
     1921 acatcggtaa ttcctcatga acaatgccat aattcaaaaa agttctcaat tcatcgacag
     1981 taagaaactt gtcctcaata ttatttatgg cttcttttaa atcagttacc gttaactgat
     2041 attttggcat tctcacagac ttcattggat tttcacttat caaattcttt ctttgacaat
     2101 atttaaaaat catatttaga acttgaataa gtgattgtaa actatttttg gcatagccaa
     2161 catttgttcc attaacgcca cattccttta aggtaaaaag caattcttga aggcactctg
     2221 gtgtcaaatc agacaacttt ttatcaccaa tccatcgaac aataattttt aattgttcct
     2281 ctcgcttatc ataggttatt tccttttgtt catttaacga acggtaatat tggaaccatt
     2341 gctcacctac aacactaaac ttgtcattgc ttgcaacaat ttttttctta agcctttgtt
     2401 gtttctccat ttccagataa gcgagttgcg cctcacgttt tgaattaaag ccacgtcttg
     2461 ttgttcgata tgcttgaaag taccatgtga tcctaccagt agaactgatt tgcttcttga
     2521 atcgatctgt tttttccatt tattgattcc tcctattttg aaggaaccca acaagcagaa
     2581 accctttgga aatctttcta tctatgtcat cattgtaccg catcttagaa agaaaatgta
     2641 acttataaag atcgaagtag tcgcaatttt tctcgatagt cattcgaatc actctttctc
     2701 atccattcta aaacatcatc acgaaaatag tgtcctcgaa tcccgtacca acagggagga
     2761 aactcaccaa gttttactaa acggttcagt gtactatcac ttatctgaaa tagtcgcttt
     2821 aaatcagtat ttgttaatac cagaggtaaa tgactgactg caagcaattt ttccgtgtaa
     2881 tcttccagtt ttttttgtaa aattgaatag aactctattt ccagagaatt aacatttgtt
     2941 ttaacttcca actccatcac ccttctctct caaaatcaaa acgaccacca cggtacccct
     3001 taaaattgta aaaaaacact ccagtactcc atcaaaacgg actagaaaag aggaattttt
     3061 aatatgaaac aaggaattgc agacataaaa ataattaaag aaattcttga aaaatctacg
     3121 gctaatgcaa tagcattcgg aacaggaatc aacttgagta cagtaaaaaa acttaaaagt
     3181 ggagagagag ctgaagaaaa attaaatctt gccgatgcta ttaaaatcac agaatttggc
     3241 atgaaaaata tgccaaccaa aatcgaaata tggaaatagt agtttttctg atctatcagc
     3301 tgttttgcca aagcacatag gaatctcacc tccccccagt aatggcgggc cgatttggtt
     3361 acggaagtat cattatcgta gtcgcgattc tcatattaaa atttgtcgct taaaagctaa
     3421 ccttgtcatg gcgtaactag agaatcaaaa tctacatgta ctgatagatt tgctattcat
     3481 ttgtcaaaga gcgctaggct attttcagcc tatggaaatc ctttattttg acccgataaa
     3541 aaacttccat agaatgaaaa ggaaagggaa aaaatacttt aacgagttgt atcaaattca
     3601 agtatcttct caatcaattt tgtttccagt tgtctacgca tatattcatc tacatacata
     3661 accattcctt tttcttcttc ataaactggt ttcatggcta accgtgaaat ataattttga
     3721 tattttgaca gaacgatgga catggcaatt gaatcaccag aagctgcggc tttgattgtc
     3781 gttagtggta tgaatggtat atatcgttta ttttgcttca tatttgacac ccaaatactt
     3841 tcctagctct tccaaagcca tttgtcgttg gtaccaaaca ctgccgagac ttttcccaat
     3901 aatatcgcca atttcacgat cattaagacc gatgaggaag gacataaaaa tgatttcttg
     3961 tctttgacta ggtaatgctg caatcgcatt tgccaactcc tcattggaaa taaagatttt
     4021 cataccaagg acaataaaag taccactact attcaaattt ggttccaaat aatagaactc
     4081 tgtacctaac cctttttgtt ccaatatttc cattgatatt tgccgttggc gaaatctagc
     4141 gtacttcttt tgaatattta acgcctcatt gcagactact ttcttacaaa aactgtcaaa
     4201 cgtatgttga atgtgggttt cctctgagtc gcccataata ttctccccct caaaaaattc
     4261 attcaactcg ttttacttct atccctttcc attattacta caatctagga
//
LOCUS       DACCVZ010000151         4179 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.155, whole genome shotgun sequence.
ACCESSION   DACCVZ010000151 DACCVZ010000000
VERSION     DACCVZ010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4179
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.155"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            92..1393
                     /locus_tag="IVW63_002821"
     CDS             92..1393
                     /locus_tag="IVW63_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7861040.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            1420..1680
                     /locus_tag="IVW63_002822"
     CDS             1420..1680
                     /locus_tag="IVW63_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAP7861041.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(2679..3914)
                     /locus_tag="IVW63_002823"
     CDS             complement(2679..3914)
                     /locus_tag="IVW63_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAP7861042.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
BASE COUNT         1206 a          670 c          866 g         1437 t
ORIGIN      
        1 taaaatttct taattatata attagttatg aacattcttt gcgttgtcat gcaatgaatg
       61 gttcatattt tattgaaaag gagtggtttt agtggaaaag ctgatgaaat gggtcgaaga
      121 gaaacttgtc ccaccaatgg caaaaattgg tacacagcgt catttattag caattcgtaa
      181 tggggttgtt tcaacattgt cattgatttt gattgggaca ttttttatgg tctttatcaa
      241 tttaccgttt cctggatgga atgaatttat tgccccttat tcggcaacga ttgttttacc
      301 ctttaggatg acgatgggat tgatggctat ttatgcaact tttgttatgg gttcggatct
      361 agctaaatca tatggattag atagtgtgac aggtggtata ttatctttag gaacgttctt
      421 tatgttacaa gttcctgtaa acgttttaac tcctgaagag gcacctcttg gctgggtctt
      481 acctatgagt tctttgggag catctgggat gtttgcgggg atcttatcta tgatttttgc
      541 agtggaagta tatcgtttct ttaaaaatcg aaatattact atcaaaatgc cagaacaagt
      601 gccacctgct gttgcccgta gttttgaggc attgattcca ggtgcagtca ttttaacaat
      661 tacttggctg attcgaagcg tcgcgggctt tgatgtaaac gctgccttat tatcgttatt
      721 cgagccttta accaatattt tagggaataa tttgcttggt gttttactac caatgttttt
      781 gatccatttg ttgtggtcat ttggtatcca tggcatgagt attgtagggg ctgttgttcg
      841 tccaatgtgg ctgatcatgt tggatgagaa tgcaaaggca ttggcagatg gtacagctgc
      901 cacccaatta ccctatatcg ctcctgaaca gttttatcaa tggacggtaa caattggtgg
      961 tgcaggagca acgatcgtgg tatctgtttt gtttatattc ttctgtaaat caaaattctt
     1021 gaaagaggtt ggtcgttttt ctattattcc tggtatcttc aatatcaatg agcccataat
     1081 ttttggagct cctatgatgt tgaatcctta catgttcatc ccgttcaact tagttccttt
     1141 agttttgact attatcagtt attttgcagt caaattagaa atggtcaata gatttactgt
     1201 tttgccaaca tggacattac cagctccaat cggcggttat ctttcagcag gaaatgactg
     1261 gcgtgttgtt atcttgatca tgatcaacac attgatagca tttattatct attatccatt
     1321 tgtaaaagct tatgataaaa agatgctgtc agatgaacaa agtcgtggag aaaacgaagt
     1381 ccagactgtc taagtttggt ttttagaagg tgggaaacaa tgtattggct gattttattt
     1441 tttgttttta tctttttatt aacggctagt caccttatat tgaatatgct agctacatat
     1501 catattcaaa tcaatcgatg gatttgggca ctggcatcat ttttgatcgt gattcttcca
     1561 aagatcattg taccgcatat gaatgttttg ttttcatggg ggacatatgt actttgtgga
     1621 atttttgcta tcaattttat gatcgagcag catagatggt ttgtcacatc gaagctttaa
     1681 atgttctaaa agtggttgta acagaagtgg ttagcttcaa gaaataagaa gaaatttacg
     1741 aaaattgctt cttaaatttt tgtgaaatgt tggcttattt ttcgtttggt tgaacttatt
     1801 accgcagatg caagcttttg accaccgttt attcggaata tgggactgtg acaaggcttt
     1861 tgtcacagcc cttttttaca taaagattat tattgtttta actgttttgg cagaaagaag
     1921 gaggaaaaaa tggaaatttt atcagcaatg gatttagaat tagtagatct actaccaaag
     1981 tgatcaagtc aaatatagat ttgggagctt acaaccatat agtaggggct gcagtatggt
     2041 gtatgaatgg taatatgtat gatgtgagtg tttattcaaa tcatgaaacg tgtatagaaa
     2101 taattgtgct gggaatagca atcagtcatg gtgaacgtga cttttagtgt atcgttgctg
     2161 acgacataga acattctgac atgatctact caatatgtgg ggattgctgg cagtttatat
     2221 aggagtatgc atcggattgc gagatcattg tctcaacaga agagggaggt tgattatcaa
     2281 agataaagtg gtaaatccta catttgattt agtaattgtt gaggggacta gcggcacaaa
     2341 tctctacaaa gcgatgcttc tagatctata tgacacattt taagaaaatg tatttgccta
     2401 attattatgg tctttctttt gaagaaacgt tgagatgatc caaccagaga aaggtgtcaa
     2461 agaatttgac taagaataaa tggcagacgc tacctatgct catttggata gcgtcagatc
     2521 ttttatttta aggatgattt tgtgtttttt agacaccgta atttaagtaa ctctaacttt
     2581 tcaatccact atttactttt tttgtatttt cactgtctgg gtctcgaata gcgaaattac
     2641 tgatgagtct ctattaaaaa agctttttct acttgaaact atattgggtg gttgctcagg
     2701 aaggtttcga tttcttgaat tgcttgttgt ggaccattta ttggaaaaac ggcttgcagc
     2761 gtgcgtgcct gctgacgaat cttgggtgaa gaaacttcgc gcagagcaat ctgcagtttt
     2821 ctttcagtca ctggttttgt gagggcgatt gcgtttccgt attttacaca atagtcaata
     2881 ttacagcttt gctcaaattg catccccaca ccgataaacg gtttgccgga ttcacaggca
     2941 gtttggacgg tcccttcccc gccgtggata aaagaaaaat caatgaattc atgcaaaaga
     3001 tgactagaca gatattctgt tattaaaaga tcttctgagt cagattgaat gtcatcaagc
     3061 agatagtcaa taggtgcaat aaccgctaga tccggttgtt tttgtaagaa gaacaaaatt
     3121 ttgcgtaaca tacgcggatt gcctgaacta cccattgcga aatagataat acgttttctt
     3181 tcttgttgct ttcgctgtat aaaagttagc acttcttcag gcaaggaagt actgagctta
     3241 gcaaaaattg gaccaacgat tcgataattt tccggcagct gttcttcttc caaaaatagt
     3301 ttaggcgttg tgatgagatt tagatcagca tccatcattt gtaaacttgt ttttggtaaa
     3361 ggaagcattt ctttttgtgc agcgtgtttg aaggcattgg ggatccatcg ggtatttact
     3421 atacgctttt ttgtccagtg ccaaagggga ttgcttaaag ggccgaagaa acgtaactcg
     3481 tggggcatca gcgcatgctc tgattgaaaa aaaggttcac tcaaagcata gggtttaaca
     3541 tatactaaag gaatcttttt attgcgggcc gataaaaaaa ttgtcacatt cgaacctgtc
     3601 acaatcagtc gaggctcaaa cttagcaatc agactctgtt cactagtgat acgagaggca
     3661 accatttctt tggtaaaagg gtttttaagt gtacgcaact ggtcaaattt tatgatttgt
     3721 tcttcttgtt ttttcgtaag gatcggcgct agtaaatgat actcaaagcc actttctgtg
     3781 atcaaaggag caaaagtttt agaaaagcca aagaatacac agtaataacg gtctttcata
     3841 gctttggcaa cctcaatcat tcgtgttgtc tcagctaaat tgaatactgc aggagcaaaa
     3901 agaattgtct tcatgaaatc ctccttattg gaatgagtct atcccttcgt ttcttactag
     3961 tatactaaaa aacacagcgt tcgagtagcc tatgtatatt ttgaatatta aactgtctct
     4021 cgctgttttc acaacttcta aatttaaatt ttgtaatcaa gttgaaactc caattttcaa
     4081 aaaaacacgc aacaattttt tgatcgattt atatgttgtg ccagataaat acgagaagtt
     4141 gtgtcattaa aaataaacat gagaacataa aaaaataaa
//
LOCUS       DACCVZ010000152         4104 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.156, whole genome shotgun sequence.
ACCESSION   DACCVZ010000152 DACCVZ010000000
VERSION     DACCVZ010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4104
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.156"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(217..1722)
                     /locus_tag="IVW63_002824"
     CDS             complement(217..1722)
                     /locus_tag="IVW63_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP7861043.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1719..2405)
                     /locus_tag="IVW63_002825"
     CDS             complement(1719..2405)
                     /locus_tag="IVW63_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7861044.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2598..4019)
                     /gene="gndA"
                     /locus_tag="IVW63_002826"
     CDS             complement(2598..4019)
                     /gene="gndA"
                     /locus_tag="IVW63_002826"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAP7861045.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1131 a          864 c          695 g         1414 t
ORIGIN      
        1 aattccctat ttttatttat tatttttaaa cacgaatatt acagcatttt attgtttttt
       61 cgttcatcta aaagatactt acatttaatt aacggatgtt attctattta attgttcgct
      121 agttttttta taatgacatc cctgaatttc tcacttgctt gtattttgta ccttattctt
      181 tgttggatat ataaaaaaac aagtaaagca catgctttac ttgtcttctg cctttgcgat
      241 aggaataaag attctaaaaa ttgtcccttg ccctactaca ctttctgcta agatacgtcc
      301 tttatagttt tcaaccagtt gtttagcgat agacaacccc agaccatttc cacccttcgt
      361 tctagctctt gctttatcca ctcgataaaa acgattgaag atcttattaa ggtcttcttt
      421 gggtattcct tcgccaaagt cctgaatcgc gatctcaaat tcattcagag tggaagaaat
      481 agagatatgg acttcttttc gtgtagttga atactttact gcgttatcca atatgataat
      541 gattaattgt tcaaagtgat tacgataaat ttgcagggtc acttcttttg tcaaatcatc
      601 atctaaagtg atcacatagt ctggatataa tatcttgaaa ttattataaa cttgataggt
      661 gacttctttt cctttagttg tttcattcgc ataatgaaca tctacttgtt ctgctcttga
      721 taagtctagc atctcttgaa ctaagctttt catacggctg atttcttgca tgctggcgct
      781 taatgattct tctaatatct caggatcatc tttcccccaa cgatttagca gactaagatg
      841 cccttcaata attgcaacag gtgtccttaa ctcatgagat acgtcttcca cgaattgctc
      901 ttgttgttca atatacaaac gcatacggtc aagcatctca ttgaatattt cagctaaatc
      961 tgccaattca tcatttgtgt cgatttcagg catgtggata tctgattgcg gatctttacg
     1021 tatagtatcc attgtatctc tgagtacctt gagtggtttt aagaaataag aagataaaaa
     1081 gaaacctaaa atactactta agatcaaaga aacaacttct aaaacaataa gagtcaataa
     1141 tagcttattt cgaatatcat agaaagaaga taattcatag aagctttgcg catagccgat
     1201 cttttctctt gtacctttag aatatatagg ctggatagat aaaaagccag tttttccttc
     1261 tagtgtaacg atcgttggaa ctttacgtgt agtctgaatc aggtttcgac tgttttcatg
     1321 ggttttaaaa atcaagttct cgtccaaatc ataaacataa agatccattg atggctgccc
     1381 tagctcagct ataaaggaat cgatcttcat taagtttcct tcgaccagtg aagtatgatc
     1441 tacgacctca tctccgtcat ttgtcgcttt cgtcagatta cgatacgtat ttactaatgt
     1501 cagttcttca tccgagttag ccaaacgaga agctacttct gaaatcgtac gctctacatt
     1561 gtttctttct tttgccacaa tcagattgat agatgattta taggtaatga cagcgaaaat
     1621 tgtaaacaca acgaatatga agaaagaact cgcaaaggcc cacttgattg tcaaggaggg
     1681 ccctttcagt tctctttttt ccgatttttt cggctttatc acgagcgcat cacataacct
     1741 gttccgcgta cagtttggat atagctttcc tccccgggaa cgtcaatttt gttgcgaaga
     1801 taacgaatat atacgtccac tacgtttgtt tcaacttctg tttcgtatcc ccacacttta
     1861 tttagtaaaa cgtcacgtgc taataccacg ttcacgtttt ccattaaagt aagcagcaac
     1921 tcgtattctc tttttgttag ttcaattact tcatttccgc gacgtacgac acggttttct
     1981 ttttcgatag tcaaatcgcg ataagtaata gtagtttgtt tagccacatt tttatcgcct
     2041 tcaatatcga ttcgacgcaa caatgcacga agacgtgcta ataattcttc gatagcaaat
     2101 ggtttgacga tgtagtcatc tgctccgtgg tcaagtccag atacacgatc gatcacagaa
     2161 tctcttgcag tcatcataat gattggtgta tttttgactt ggcgtacacg tctgcagact
     2221 tctaaaccgt tcaattctgg gagcatcaga tccaacaata tggcatccca ctcattattt
     2281 aatgccgcat ctaaaccagt tcggccgttg tagtggactt ctgcgttata cccttcatgc
     2341 ttcaactcta gctcgacaaa tcgtgccaag ttcttttcat cttcaatgat tagaatattg
     2401 ctcatttatt attttatcct ttctattcta ctggcttttt aaaaactcta tcattatacc
     2461 gataatatgc ttaaaaatct atagtcattt tatcatggat agcaatttta aaaaagagct
     2521 gaagtctact cataacaatc gacttcagct ctttcgtcct ctttttattt tctcatttcc
     2581 taacagccga aagactatta ttcttcatgg taccatgagt aatggaagat tccttctttg
     2641 tcgacacgct cataggtatg tgcgccaaag taatcgcgtt gggcttggat tatatttgca
     2701 ggcagacgtt ctgctctgta tgaatcgaag taagcgatgg ctgatgagaa agtcggtaca
     2761 ggtacgccag cttggacagc caaggcaacg acgtctctga ctgattgctg atattttttc
     2821 gtgatttcaa cgaagtaatc atctagcaat aaattttcga tctcaggatt tttgtcatag
     2881 gcatccgtaa ttttttgcaa gaatcgagct cggatgatac atccagcgcg ccagattttt
     2941 gcgatttcac caaatggcaa gtcccaatca aattcttttg aagcgacacg taattgagca
     3001 aatccttggg cataactcat gattttactg aaatacaacg cttctcggat tttttcgacc
     3061 aattcttttt tgtctcccgt gaactcaaaa tcgttcgtac gagacaaaat cttgcttgct
     3121 tgtacgcgtt cttctttata agcagaaata tagcgggcaa atacagattc agtgatcaat
     3181 ggaagtggca cacctaagtc aagcgcgctt tggcttgtcc atttacctgt tcctttattc
     3241 ccagctgcat caaggatcac atctactact ggtttacctg ttccttcatc gtctttacgt
     3301 gtcagaatgt cagcagtgat ttctatcaaa tagctgtcta attcgccttg attccattct
     3361 ttaaagatat cagccatttc ttctactgaa aggtttaaaa tattcttcat taagtcataa
     3421 gattcagcaa tcagttgcat atctccatac tcaataccgt tgtgtaccat tttcacataa
     3481 tgtccggctc catttgggcc aatatatgtg acacatggtg ctccgtcttc tgcttttgca
     3541 gaaatttgct ctaagattgg tgcaactagc gcataggctt ctttttgtcc accaggcatg
     3601 attgaaggtc cttttaaagc tccttcttca ccaccggaaa cgcctgtacc gataaagttg
     3661 atgccagagt tggctaactc ttcattacga cgcatcgtat ctttaaagaa tgtatttcct
     3721 ccgtcaatca aaatatcgcc tttatcaagg tgaggaagta actcttggat tgttgcatct
     3781 gttgccggtc ctgctttgac cattagcaag atccgacgtg gtttctcgat agattctaca
     3841 aattcttcga ttgtatatgt tgctttgaaa tttttatctg ggtgttcttc tactacagcg
     3901 gttgttttag cccctgtacg attgaataaa gccactgaat agccgcggct ttctatgttc
     3961 aaggctagat ttttacccat aacggccata ccgacaacgc cgatttgttg ttttgacata
     4021 tgaactcctc ctacatacgg gatttctccc taatctctta cattatagct taacacggct
     4081 acattgcaaa ctaaagaaca acat
//
LOCUS       DACCVZ010000153         4067 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.157, whole genome shotgun sequence.
ACCESSION   DACCVZ010000153 DACCVZ010000000
VERSION     DACCVZ010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.157"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            86..1435
                     /locus_tag="IVW63_002827"
     CDS             86..1435
                     /locus_tag="IVW63_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7861046.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1563..2153)
                     /locus_tag="IVW63_002828"
     CDS             complement(1563..2153)
                     /locus_tag="IVW63_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAP7861047.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2300..3652
                     /gene="brnQ"
                     /locus_tag="IVW63_002829"
     CDS             2300..3652
                     /gene="brnQ"
                     /locus_tag="IVW63_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAP7861048.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1173 a          744 c          789 g         1361 t
ORIGIN      
        1 aaaattttgg aatcttagtt gtgtttttca gaaaactctc ttaatatgga agtaattaaa
       61 cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc gtggactgaa
      121 aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt tgtttttagg
      181 ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc ttattactgg
      241 atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa acaccaataa
      301 ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt tcatcactgg
      361 ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag ccatcggaat
      421 gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga ttgcattagg
      481 tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag agttttggtt
      541 tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt atatgatcct
      601 cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt ctcatggcgg
      661 attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa cctttgcttt
      721 tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg aaaaagtgtt
      781 gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag gatctctttt
      841 tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc catttgtaga
      901 agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag tcgtattaag
      961 tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc ttcgttcttt
     1021 agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc atgtgccagg
     1081 gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga attacgtgat
     1141 gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct tgtttatctg
     1201 gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca aaaaagctca
     1261 ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt acatggcctt
     1321 tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac taacacctgt
     1381 gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga agtaagaaag
     1441 tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa aattgcttct
     1501 taaatttttg tgaaatttcg gcttatttct tggagataaa agcttctgtc ccagcctctt
     1561 ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata ggaaaaaatc
     1621 caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa aaagacaccg
     1681 gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt tgacaaaact
     1741 ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa gataccaaaa
     1801 gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa agcttcaggg
     1861 ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag caaaaagata
     1921 ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg atgatggttc
     1981 acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt atttcggatg
     2041 acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac aagaactctc
     2101 aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt cacgatgatt
     2161 cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata accatcgttt
     2221 tatataggga attttctgaa aattgttgca tatttttcga aattttgtta cttttaaaaa
     2281 aaccgtaaag gagttatgta tgacaaaaaa attatcattt aaagactatc tttttatagg
     2341 ctccatgctt ttcggtctat tttttggtgc tggaaatctt atctttcccg ttcatttggg
     2401 tcaagaagca ggcgctgcta ccttttgggc gaatctaggt ttcttggtta ccggtatcgg
     2461 tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa agctcaggtg tatatgaatt
     2521 agcaaaacgg ataaatcaaa catatgcgat ggtttttacc atcttgcttt acttagttat
     2581 cggaccgttt tttgctttac ctcgccttgc aaccacatct ttcgagattg gtttagcacc
     2641 atttatcgat cctagcagac agacgctata tctagcaatt ttcagtattg tattttttgt
     2701 gctggcttgg tggttttcaa gaaaaccgac aaagatatta gattatgttg gaaagttcct
     2761 gaatcctgca tttttggttt tattaggtgc tttgcttctc cttgcttttt tgaatccact
     2821 aggttctgta aatcaagcgc ctattcagcc aaattatcaa gagcatgctt ttttcacagg
     2881 gtttactcaa ggatataaca cattagatgc gcttgctgct ttagcatttg ggatcatcat
     2941 tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct gaaatcgcta aagacacgat
     3001 caaatctggt gcgatcagca ttatattgat gggaatcatt tatactttgc tcgcttattt
     3061 aggtgctatg agcttaggta gctttgctct aagtgaaaat ggcgggatca cgctggctca
     3121 gattgctgat cattatttag gtacttatgg cagtatctta ttagcattta tcgttatatt
     3181 agcttgcttg aagaccggta ttggtttgat tacagctttt gcagaaacat tcacagattt
     3241 gtttccgcaa agaaattacg cattctttgt tgcacttgct agtatccttc cttgtttagc
     3301 ggcaaacgta ggcttgacga atatcattca attttcgttg cctgttttga tgttcatcta
     3361 tccattagca atgacactga ttttactagt gttagttggt cctttgttta agcagcgtac
     3421 ggctgtttat cgaatgacta cttattttac attgattgct tcgatttttg atgggttgaa
     3481 cgcttgccca gaaactatca aacaaacacc tattgttcaa aatcttttat atgttgcgga
     3541 aagctacttg ccgtttttca aattggggat ggggtggatc gtaccagcag ttatcggttt
     3601 tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa gtagcagatt gataaaagag
     3661 gttgtgaaag agacgttcag ccttgagcaa taaaaagtaa ttttgaaaaa tggcttctca
     3721 catttttgca taaatttgac ttaataccga gaaactgact tttgaacacc gtttattgag
     3781 aggtcgtgaa aaagccgctt agtttcaagt attaagaaat attttgtgaa aatggcttct
     3841 cacatttttg cataaatttg acttaatacc gagaaactgg cttttgaaca ccgtttattg
     3901 agcgtctata aactgacctg agtattagag aaacaaaacg gcaaagtagc tccatatact
     3961 ttgccgtttt gttttgaact aataccgaag agaagctgat caaacaacat ttcttttata
     4021 atatagattt tagacatata tatgatataa aaatagtttt cgcaaaa
//
LOCUS       DACCVZ010000154         4037 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.158, whole genome shotgun sequence.
ACCESSION   DACCVZ010000154 DACCVZ010000000
VERSION     DACCVZ010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4037
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.158"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            854..1066
                     /locus_tag="IVW63_002830"
     CDS             854..1066
                     /locus_tag="IVW63_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861049.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(1344..3143)
                     /locus_tag="IVW63_002831"
     CDS             complement(1344..3143)
                     /locus_tag="IVW63_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAP7861050.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(3267..3863)
                     /locus_tag="IVW63_002832"
     CDS             complement(3267..3863)
                     /locus_tag="IVW63_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP7861051.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1449 a          711 c          689 g         1188 t
ORIGIN      
        1 tatattaaat attatacaga taataacgga atattatcat cgaaacagct aacaaaattg
       61 tcataaaaaa cgagatggtt gatattagaa cttgtgtttt tgtttaggtc tagagataaa
      121 gagagacaat ttccaaatat atgtaatgaa tacaaaaaga cgtttgtcgc ggattaccgt
      181 tacaaacgtc ttttattgat tttccgagat ctcatcagtc gccatttgga atggttcact
      241 ccttatctag attcgtttaa tgctcggact gcttgttcga ttgtaatacc aaacgcaacg
      301 ttattttcgt tttgtgcatc aatcgccata aaacggttag aagttgtatc aaaagctacg
      361 cggtattgca tatttgtttt tgtaaacgtc ataaaattca tctcctttgt aatgtaattt
      421 agttcttgaa agtttccttt aaactttcga acttatacca agtttagcat cgtacgtttt
      481 ttgatgcaat taaaaagcat ttatcatttt ccttatttat tttttcttaa atggtttagc
      541 tattttcttt taatccgata agtagcccaa tcatcaaggt tacaaatact attgcttgaa
      601 tataaatcat atgctcacct ctttataaat aacttagcaa tataaagaaa aaaacgcacg
      661 aacaacatag gaatataaac aaacgttttt gtcacaacgt ctaagatcgt gttaaaaaat
      721 agttatctaa aaagcagaaa gatactcaaa ataaaaaata aaaaaatgga taaaaacgtt
      781 ttcaaataca aggtaatttg ttattataaa ataaagaaaa aacaaaataa aaataaagaa
      841 aagagggaat gaaatggtaa aagcagaagt aggaagatct tatatatgca aaccgatcgg
      901 agtatctcat gaactaatcg gctgtattga acgtacatat atcaacacgg ctgtcgtgta
      961 tgttgaaagt tatgaccaac gagactatca acttatcaat gaaagcaagt atcgcatgct
     1021 cgtaaaattc tgtgatatta gcgcacctgc tgaattggtt tcttaaacag tatttttgag
     1081 aattcgcaag aactccctta taatataaat aaagacagaa gggagcgaga agatatgcca
     1141 aaaagaaaaa gttcagggaa aatgggaatt attcttgcag tgatctctgc aattcctgct
     1201 attttagcta ttgttcgtgc gatgaaggaa tcaagagaaa gttaagcaca cattatgagc
     1261 gtcaaacaaa aaacgcatat acctgcggtg gcaggttatg cgttttttgt tgtataaaga
     1321 cttttttcat taacgatttt tgattagccg actcccaaaa caaaatttag cagtttatct
     1381 gaataagtga tttcttcatc tgtttgtttc acactttcat ttagtagtcc catctcatcg
     1441 gttatgatac catccacacc ataaaacatc atgcgactca tagcatctga atcgttgatt
     1501 gtccatacat atacttcttt tccgtcttgg tgggcagaat taatgaagtt acggttgatc
     1561 gtactatatt ccattgtcag aaaatcagca ggcgtcacag ggggcccaac aatattgaaa
     1621 ggtaagatgt agcccacata aaagtttggt tctgcttctt ttaaatctga aacggtttgg
     1681 tacgtcaaac tttgcaaaat atgatggttc tctaagataa ctttgcggta tttatggaca
     1741 aatcgttcga caaggtcatc cgaatctttt ttagaggtct tgatctcaat aagtaatttt
     1801 tggtttagct tatgtgcttt ttccaaataa gaatcaaaag aacaaacagg ggcttgcact
     1861 ccgttttcag taactgtaag atttgtcaat tctttcaatg taagatcctg tggtgttcca
     1921 tttacccctg ttaagtgacg aagatttgca tcatgcatca ctacgaaatg accatctttt
     1981 gtttcctgaa catccatctc tacataatca ggatgatagt ctctgcttgt tttttcaagt
     2041 gcttctaaag tattttgcgc cccattttgg gtactcacac ctctgtgaga gacagtcact
     2101 ggttttgtct gaacagctga agtcagataa tccatattgt aaagacagac gccaataccg
     2161 aaaaaaactg caaaaagagt caaaccagtg tttttcagcg cagagaaacg caagttgggg
     2221 gcttgtggga taaaccactt agggatctca ggcaagaagc cttcgtcatc catgaaatca
     2281 acaatgatat aaaaaatccc tacggtagac atcacgatat tgaataataa aatcccttgt
     2341 aaaagcgtca tagcaaacac agcgctgatc aatgcatagt ctgggaaaaa ttgttcaacc
     2401 atactttgtg ccaaaataac aacgatatat cctaaagaag aaaggagtaa aatcgtaccg
     2461 ccaatcacaa taaattggcc cgtgatggcc aaaagacgcg atttggtcaa tgaccagctt
     2521 tcccgaatgg ctgctcgaaa aggacgatct cgtagaatca tttccggtaa agcaaaaatc
     2581 agtcgaatcc caatatagcc aaggaaaata taaacgagta aaaaggaact gacgatgatc
     2641 caacgattag caaaaataaa atccataatg aaagcgggga tttttatttt tgacagtaga
     2701 tcagaattaa aacttaatcc gctgatcggt agaatcaata aaaaataagc aaggaaaaac
     2761 aaaaaagtaa tgggtctcac tttcttcagc tgaagtatcg tcaagtgtaa gagttgcttc
     2821 aaagagattg gttctttctt tttaataaaa aaaacactca tcaaaagaaa agtaaattcg
     2881 aaataaacta acagtaaaat cgtcatcaaa actacgatta acgagagtag aaccccagga
     2941 tgttgagaaa aaattgaagg aatattgtca taagacaaat agtcaattgc ccctcggtgt
     3001 aaaataaaac gggtcgtact gctcaataag ggtaaacaaa taaataaaat aaagccatgc
     3061 atcagcaaga catcacggaa ataagcttgt gttcctttta aaaagtccca agcattacct
     3121 aagctacgtt tcaaataatt catcctatca cctgctcttc acattgtagc gcaaatctaa
     3181 tgaaaaagga aagggtgcag tgtgttttgc agaccctttc ccagatttaa cattgtcaat
     3241 caatgactaa ttttacaaaa taaatattat ccaagaagac cacttagata ttgacctcca
     3301 taaatcaagg ccatactata taagaaaatc gacagtggtt tagcaatcaa aatgattagt
     3361 gtatatcgtt tcactgacat gtttgtcaat ccagccatca aacataacgc atcgtcagga
     3421 gcaactggaa gaaaaatagc tagagcaaac agcttctcaa aacggttttg attatccagc
     3481 cagccaatat atttgttata tgtcttatcg ctaatcatgg aaagtatgaa tggctttcca
     3541 taacgacgcc ctagcagaaa aatgataatc gaaccaatgc agattccaat atagttatag
     3601 ataaatccag cataagggcc aaatatcagg acaccagctg cagtactgat ccctccagga
     3661 atgattggaa taactacttg caggatttgg atgaagacaa aaataatcgg tcctaaaatg
     3721 atggaatcac ctactaatcc tcttaacgca ttcaaatctt tgaaaacacc taaattaata
     3781 aaataaatcg tcagcgcgat tgataggcct aatccgataa tggatatgaa atttatcagt
     3841 tttcgagagg cagcaatatt cattattcat caactcctta gaggttcttt gttaactata
     3901 ctttactaga aaagcaacta actgcgccat tttttgatat gacagaaaac aaacaatttt
     3961 gtaagttcat cataagtata aaagattgat ctcaaaaaaa catccaacta aagacttatt
     4021 taataacttg ttttttt
//
LOCUS       DACCVZ010000155         3719 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.159, whole genome shotgun sequence.
ACCESSION   DACCVZ010000155 DACCVZ010000000
VERSION     DACCVZ010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.159"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..682)
                     /locus_tag="IVW63_002833"
     CDS             complement(<1..682)
                     /locus_tag="IVW63_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HAP7861052.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKGER"
     gene            complement(654..1853)
                     /locus_tag="IVW63_002834"
     CDS             complement(654..1853)
                     /locus_tag="IVW63_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP7861053.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENAQTVDKVHFMDDVYSLFFYNRFMKTNA
                     RSDSYDV"
     gene            complement(1983..3359)
                     /locus_tag="IVW63_002835"
     CDS             complement(1983..3359)
                     /locus_tag="IVW63_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7861054.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(3359..>3719)
                     /locus_tag="IVW63_002836"
     CDS             complement(3359..>3719)
                     /locus_tag="IVW63_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7861055.1"
                     /translation="NIRLVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARA
                     LVSDAPIILADEPTGNLDSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILE
                     LSGKKLKKVNKMNLEVE"
BASE COUNT         1118 a          724 c          547 g         1330 t
ORIGIN      
        1 ctcgttcgcc tttgacgtag tagccgcttt ccggatcagc tttacttatt tttctttctt
       61 tcagcttcac ttccttttct aagtccaaag taaaagggcg ttttccagcc tctattcgtt
      121 gacgattgat ctcatcttct aattcatcct gataggcttt cgcttcatca tgggtcattt
      181 ctttcgtaaa cttatgttta ttggcgttag ctttgatgtg ggtagaatcc agatacaaat
      241 tatcctctgt tacaaaacct gctttaactg cttgttctaa aatataggca aaaatatcct
      301 caaacaccgt cgtttctcta aatcggcgaa cataattctt tccaaaagtt gagaaatggg
      361 ggattttctc ctcgaaggag tagcctaaaa accagcggta agcgacattg gtatcgactt
      421 ccttaatggt ttgtcgcatg gaacggatac cgaataaata ctgaataaac accaatttga
      481 tcagaatcac tggatcgata cttgggcgac ctaaatcgga gtaagtggct tcgacgattg
      541 gataaataaa ttcaaaatca agcgcggcat caatctttcg aacgagatga tcttgaggaa
      601 ctagatcatc aatcgtaagc atcgcaaatt gatttctacc attcgtattg tttttagaca
      661 tcatagctat cactccttgc attcgttttc ataaatctat tataaaagaa aagactgtag
      721 acatcatcca taaaatggac tttgtctaca gtctgcgcat tctcattaga gaacactccc
      781 ttttttgtga cttttctgaa gctagagtga atactttcaa ctgcattagt agtgtacatg
      841 atttttctaa tggcgctgcc ataatcaaag agttgttcaa catgagaaaa gtttcgtttg
      901 catacatcta ctgcaccaga ataatgagac caccgatttt gaaaactgtc gaaggcagcg
      961 tgtgcagcgt ttaaagaaga agcactgtag aattttttca tgtctcgaca gacttcctta
     1021 taatccttac ttgggaggta tcgtaacgca tttcgaacaa gatgaacaat acagcgctgc
     1081 acaatgacag aaggaaaaat tgcttttgcg ccttctttga gaccggaaac accgtccatc
     1141 gaaatgaaaa aaacatcttc tacaccacgt actttcagtt catcaaatac ttgcatccag
     1201 cgatttttag attctgtttg attgagccat aggcctaaaa tctccttgtt tcctttaaga
     1261 tcatagccaa gaatggtgta cacagcatat tctttagctt catagttttc gcgtaaagtg
     1321 acgtacatac aatcaacgaa tagaaatgca taacacttgg ctaatggccg agcttgccat
     1381 tcttccaatt caggaaggac ggcatccgtg atatcagaaa tcatttcgtg ggaaatatca
     1441 aagccgtaaa tatcttcaac ggttgcggcg atatcgcatt gactcattcc tcgtgcatac
     1501 atggaaagaa ccttaccttc gatgtcggag acatctcgtt ttctattagg aatcaactca
     1561 ggttcaaaag aagcctcccg gtctctggga acatcaatgt ttactttacc aaagctcgtt
     1621 ttaagcgtct tattgccata accgtttcgt cgattgtcat gtttctttgg ctctttagaa
     1681 tgggcgtcat accctaaatg gttattcaat tctccttgaa gcattttttc aaataaggga
     1741 ccaaacacat cttttaaaac atcttgcata tcctctacag attcgggttg ataagtattc
     1801 aaaatggatt cagctaactt ctcagcatca ggatttcttt tctttctagc catcgtgtaa
     1861 tcacctcttg atcttatttt agaaaaataa aaaccgtgaa gcaaccaccc gcctaggatt
     1921 gatggttact tacacggttt atattacact ctcatttttg gtgctaaaaa gcaccgaaaa
     1981 ttttaattat tgtcaattaa taattctttt ggattccttc ttaatatatt gaatgaagaa
     2041 ataatcaatg atacaagaag tactaaactc ataaatataa ctacataaat catgaattta
     2101 ggtaatacat tgatatctaa acttgataat gtcttgttaa atccttcagc ttctgcccca
     2161 ccacctaatt ggctagatgc agattgttta gctatttgtt tagctatatc accagtaacc
     2221 ttattcaata tattattccc aagcttgtca gctgtatatt gagctaagaa ataggaacca
     2281 acgaatgcgg ggattgatat aaataccatc tcaattagga attgaccaaa aatttctaat
     2341 tttgatatac ctaatgatag taatactgct atttctttct ttctagcatt catccataag
     2401 aataataata atgaaactac aactcctgca aatattaatg agccaaaaaa taatttattt
     2461 gaaattgagt aaatacctga tatagattgt tgtaatgcag ggtaatttga tgaactttta
     2521 atcaaattat attctctcca atttatatct aatttcccaa gatcttttat tacactatca
     2581 agattcttat caccttttac aaagaatgtt gcatcttggt atacagctgt atcttcggta
     2641 ttaccataaa ctttagcagc tgtatgaata tcagtgatta atgtattttc gtatagttct
     2701 tgtgctgcac ttactccacc gctattatgc ccatcgaata gacctttaat ttctacttct
     2761 actgtttcat ctgcaccttt ctcattatca gcatcaaata aattagattt tatttttatc
     2821 ttatctccaa ctttaaggtt atttttttca gctaaatctt tatgcattaa gattttattt
     2881 ttatcttcat tttctaaatg ctttccttct actaatttat atgcttctga tacaaatttt
     2941 gtttcttttg ttgagtcgtt aaccccagtt aacataactg ttcttttaaa attctttgct
     3001 ctttcaggtg attgattcgc aagagtctct tgagtttcaa taatatcata atcaactaaa
     3061 tctgcaacac tgtttattct ttttacatag gagtctatac tatctgtttg agatatcttt
     3121 ttaatatctt caccttttac atttccccca cctctaggtg ttcctggatt tacttgtcta
     3181 tttatctcca tagaaaaact atttgttata ttagcaaatg tttcttttga agctctgtcc
     3241 gtagcatctt taatagataa actaatgaga cttaaagttg acatagataa aataactaat
     3301 atgataatta atgattttaa actttttcta gttacataag caaatgcatt ttttatcatt
     3361 attcaacctc caaattcatt ttatttactt ttttcaactt tttaccactt agttctaaaa
     3421 tgatatccgc agaatctgct acttccttac tatgtgttac aactattaca catttatttc
     3481 tatctttagc taatgtcttt aatatattaa ttatttctcc agcagtaaca ctgtctagat
     3541 taccagtagg ctcatcagct agtattattg gagcatctga taccaatgct ctagcaatag
     3601 ctactctttg ttgctgtcca ccagataatt tcataacatt tctttttatt tgttttttat
     3661 ctaaacctag ttcaaacaag atactttcat ctgctgattt atttactaat ctaatattt
//
LOCUS       DACCVZ010000156         3556 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.160, whole genome shotgun sequence.
ACCESSION   DACCVZ010000156 DACCVZ010000000
VERSION     DACCVZ010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.160"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..2303)
                     /locus_tag="IVW63_002837"
     CDS             complement(<1..2303)
                     /locus_tag="IVW63_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861056.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVET"
     gene            complement(2975..3243)
                     /locus_tag="IVW63_002838"
                     /pseudo
     CDS             complement(2975..3243)
                     /locus_tag="IVW63_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          994 a          790 c          561 g         1211 t
ORIGIN      
        1 gtttctacca gctgatatgc tcctggtgct aaaccgtcaa ttgccagttt tccatcttct
       61 cctgtagtta aaccggtttg tagcgtttct ccttctcggt tctgtaactc aaaaacagct
      121 ccttgaagga cttcaccact gccttcagca tgtttaatta gttcaacacc acccgtatca
      181 aggatgtttt caatggttaa cgtcacttct tctatggagt attcatttat aaaaacatca
      241 tgtaccgtcg catctaaaag atacccttcc ggtgcttctg tttctcggac ttgatagcta
      301 cctacaggaa gcggttcact taaaaattct ccgttttctg ccgttatacc ttcttgtatc
      361 acttgtgaat cgcttgataa aatttcaaat tttgctcctg ccagcctttg gccattctca
      421 tcagttttaa ttactttaat acgcccatcg attttccttg ttcttacagt actcgtattc
      481 aatcgattgt cactattcac aagcgttgca aagtttaaaa tttgatcgcc gaccgcatac
      541 gcctctacat tgaccttaaa agagagggta aaacttgtcg gaccaccaat cgtattattc
      601 gcactgaaac gaactattcc attattgact tcggcatcaa tgaaagaggg aatatctgat
      661 agaaatgaca caaattccat gccttcttcc aaaacatctt caataacaag cgtatttctt
      721 gttccagaaa acatcgagac atgcagagta tacgttagtt cattttcatt gagattgata
      781 acatttttgt ccacactttt tcttaaagag attgccggaa gattactttc agggattctc
      841 aagcggtagt ctcggctcat tacctgatta ttgtaggtca tactcgctcg attccgagaa
      901 aacccatcct cttgtcttcc ttcattgaac aagtcgacat cggtcacttc aagagcatat
      961 tcaataaaat acgattgacc ctctgctaga ttaccaaagt ccacaacaag tgtattcgtt
     1021 tccttattaa aagatacttt gtccacaaat tcctcggaaa cataatgagt tctaacgttt
     1081 gcttcacctg gattcgttac ttctgcgatc cgaaccccac ctgaaatagg ttctctattt
     1141 ccagtggaac tccatgtagt cggattcggt gccaaagttg ttccttgcgg tagtacatcg
     1201 gtaaccacta caccgtcttt tcgtgatcct tcataattta cctgcaaaat aaatttatta
     1261 ctgttggtca cgtcttgccc gtcaatcagc agattcccaa gatttccttg gctgtcgatt
     1321 tctctagagc catagtataa tttcgaaaaa atgggtcttg atgaaggaat aggcgtaatt
     1381 gaaaattccg tgtttgctgc tcgctcagca taagtaagac tcacttgaaa gtcattattt
     1441 ggctcagtac cgcctgattg aaagaaagca acttcaaacg tgatactgaa tgtatacgac
     1501 tgagcggctt catttaatcc ttcataatca aaggtaaatg gaaaaacaac gtctgtgcct
     1561 tcttggtaaa atgccagtgg ctttaaaggt gaatcatcag cgacctccac tctaatgaac
     1621 tcaattaagc caatcgatgc tctaggaact cgtacgacca tctccccata ttcttcaaga
     1681 atatcgccag cgcctccttg aatgtatccc tttaacgttt gtgtatgcct gctcggcaaa
     1741 gtggggcgct cagcagagat gccgatgtca taattcaaga gctcctcttg tctttcaatc
     1801 tgagattcct gcgttataga tggctcagat gatctggctt cattaaaaga ttcacttaag
     1861 ctttcttctg gtatattaaa agattcactt gtgctttctt ctggtacatt aaaagactca
     1921 cttgtgcttt cttctggtac actgatttct attgagaccg tatttgattg aatatcaccg
     1981 cttcttgcgg tcaattcgta tttacctgaa tgctgggaag aataagtaat cagacgttcg
     2041 taatcattga gttgcttcac ttccccttca atcaaatcct cactcttatc aatgaccaat
     2101 gcatttagca ggtctggtgt tcctctgact cgcaactgga actgctcacc caaagcagcc
     2161 tcctcttgat caacttcgat cgtcagcgaa cgctctggct gttctgctaa agactcagct
     2221 agaaccgtta tgttcccaaa ttgattgatc acaataagca taactagaaa catacttaac
     2281 agtttatgaa atttgttcct cactattact cccccttata attttgacta aacaacaagg
     2341 tacccgataa ttttctaaaa agattcccca actcaaaatg gctgcgttac ctccctcgta
     2401 ttttcggttc aactcaagcg ttgcaatgta agctgtaaac aaagctaatg attgccgatt
     2461 gtcttctgtt gattgattcg atagctttgt atgactttta gttgtccgtg tggcttaacc
     2521 ataattatga tttcacgatt cctcctgcca gtgccttgca caagctggag cgtaacccta
     2581 atagttattt tgttaatgta cttatatact tttatacttt tccattagaa acaatcacta
     2641 aatcgttgat accaaggtca gactctagaa tttcatcagt gagtccctgt attggttaac
     2701 cttcatcaat cccaaaaaaa tatatcaatg cttagcatca aaatgaatat atagtttaga
     2761 atacttggga ttcatcgata actgatcgct tatttggcca tattatttgg cacttggttc
     2821 aactaaacgc atttaggatg ttccttcatt ctcgtcatgg atgttctcaa accgtcatta
     2881 ctaataaact gtccaccgaa tcgatggttc atttcttgca ttttccacgt ccaattactc
     2941 tttttgctct ttatttgggc gtagtttcac tttcttaact tgtatcgtct tccatcaact
     3001 ccttaatcat cttcttagct ttattggctc ggtttccttg taaaaggtat ctacaaatag
     3061 tgacaatctg tattaaatct tcatcatttt ctgtaatgtc aataatttct atattctgta
     3121 ccatatattg caaagggttt cactaagttc ataaccgaag cgaattaaac aacttttgta
     3181 tagaataact accttttcta tttttccatt ggtaattcta tctattaatt ggtttaatcc
     3241 ttttgttgta gttgattcca ctaccaagat gattctctcg aattttaaag cttgaagatg
     3301 tattgctatt tttgctaact ggcgtatttg caactatttt tcccttctat tcttccttca
     3361 ttgattcccc tctaaaatta ctatccataa aaaattgcat aaatgacaat agtatttata
     3421 ttagtcatac tgctttttaa cacagcaaat tccagaaaaa cattcgttac atatttgtga
     3481 atttttccaa aaaataacat ttttataaaa cgacgaaaaa taaatcacta ccagtcaact
     3541 tctataatat taccaa
//
LOCUS       DACCVZ010000157         3445 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.161, whole genome shotgun sequence.
ACCESSION   DACCVZ010000157 DACCVZ010000000
VERSION     DACCVZ010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.161"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(50..985)
                     /locus_tag="IVW63_002839"
     CDS             complement(50..985)
                     /locus_tag="IVW63_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP7861057.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            1171..2130
                     /locus_tag="IVW63_002840"
     CDS             1171..2130
                     /locus_tag="IVW63_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HAP7861058.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(2216..3310)
                     /locus_tag="IVW63_002841"
     CDS             complement(2216..3310)
                     /locus_tag="IVW63_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP7861059.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         1059 a          710 c          558 g         1118 t
ORIGIN      
        1 ggatccagtc aaaggcttct ttcttttcat cccctacttt taaactcgtt caatgaacat
       61 attggcttaa aaattgttgg actacttgct gatatttttc aggatctgtc ttgtatgctt
      121 ccgcatgctc ggctcctttt acaacatact tttcttttgg tcccttcgtt gcacgataga
      181 ccttatctaa catttcaaat ggtacaaatg tatcttcgtc tccatgtata aagagcattg
      241 ggcgctggtt tttcttcaat tgttccactg catttgcttc accgaaaaag tagccagcac
      301 ggacttttgt cactagactc gttacttgca taagcggaaa tgctggaaga ctaaacatat
      361 cgtctagctg ataagcaagc tcatcatgaa cggaagaata accgcaatct tcaatgattg
      421 ctttcacatt atctggtagt ttttctccgc tagtcatcat aactgttgct gctcccatgc
      481 tgacaccgta tagaacgatt tcttgcgatt ttccattgtt ttctagcact ttgtttatcc
      541 actgtacata gtctttacgc tctggccatc caaatccaat gtaatcccct tcgctttttc
      601 catgtcctct tgcatcagga acaaggacat tgtaacccat atcatgaaac atctttgcgt
      661 aattggtcat cgtttcagcg tttcccatat agccatgagc cacaagagct gttttttcac
      721 ttttcgtttc agcaggaaga taaatcgctg ataatttcag accgtctttt gaagtgatgg
      781 tccaatcgct tcggttttct tttgaactaa accatttatg tgcatccgtt tctttggatg
      841 tctgtgttgt accaggtgta tcttcgtcta aaaagtcttt ctcagaaggc acaacagcat
      901 aattataaaa ataattccct gcaaacacta acgcaacaat cagagctaaa gcgacgccta
      961 aaaggatttt catccaaagt ttcataaatc atccatctca tttctctttt ttcatataac
     1021 cttgaattag tataatcaaa gaatctctac tatgcaatgt tcatttttat aacccgcgaa
     1081 ttgtaaaatt aagttagaaa aataaaaagg catttatggt acactcaaat tgtatttccg
     1141 acgaaagaaa acaaaggagt gtaaccataa atgacctaca aacatcttac catagacgaa
     1201 ctgacaatga tagaatcata ttatcttcaa cataataagc cggttgaaat cgctaaccga
     1261 atgggacgtg ctatacaaac tatttataat gtagtcaata agttcaagca aggcaagact
     1321 gctcttgatt attggcacca gtataaagaa aataagaaaa aatgtggtag aaaagtcatt
     1381 caattacctg ctcatgaagt agattacatt aaagagaaag tcactcttgg ttggacgcct
     1441 gacgtcatta tcgggcgaaa agaaaggtct gtttcatgcg gtatgagaac actttatcgt
     1501 ttattttcta aaggaatatt tgatattgac acactaccga tgaaaggtaa aagaaaaccc
     1561 aatggccatc aggaaaaacg gggaaaacaa cagtatcagc gctcaatcca tgatcgacct
     1621 gataattatc ctgatttcaa ttctgagttt ggtcaccttg aaggtgatac gatcgttggc
     1681 attcatcata aaagtgccgt cattacttta gttgaaagat tatctaaagt cattatcacg
     1741 attaaaccca acggccgtaa ggcattagat attgaaactg cccttaatca atggttttct
     1801 cgcttcccta aaaacttctt taaatctatt acgtttgact gtggaaaaga attttctaac
     1861 tggaaagcca ttagtaacca acatgatatt gatatatatt ttgcggaccc tggaacacct
     1921 tctcaacgcc cattaaacga gaattctaac gggattctgc gtcgtaatgg actgccgaaa
     1981 tcaatggatt ttagaaaagt gaatcagaca tttatttcca gtgtcagcaa tcaacgtaat
     2041 catattccaa gaaaatcatt gaattacaga acaccaatcg aaatattttt gagctatgta
     2101 caagaagcat tttattctag cttaatttga caaatcataa cctataaaaa aacaaaataa
     2161 aaaagcagaa ataactggct atttctagcg gattatttct gcaataacta attatctatt
     2221 ttttattttc aattaattta aagcttgacc atggtttcaa aaagtcaagg aggaataatt
     2281 cgtcatcgga gattcttcct acaacattga cacgtccgtc gtttttcata tccttcaagg
     2341 cgatttgtgt ttctcctttg tattgaccgt acccttcatt gtcaatcagt acatccccat
     2401 gatgcatatc tcgcgtatta tgaggcggga aatctttatc tttgtagtat acacgagtca
     2461 tcgttgaacg aaggatatat tctgagcgat cccctcgata actatgaagg ttatcaaaca
     2521 agcagattcg ttcgttttct gtaatacctt cttccgtatc tactttcaat gttggataat
     2581 ccgcgttaaa tgcttctgcc atttctttca attcttcttc acttgcgtac gcatttccaa
     2641 tagaaatatc atcaatcaat cctgtaagga ttaaatgctt cacttgtgtc gcaatttcaa
     2701 gatctcggtg gtcttccagc gtgcacaagc catcttgcgt aggccaaggg ccaaactcag
     2761 cagattgcga attgacgaat gccatcgtat tcaaattata ttttctgaat ttttctgaac
     2821 aaaaaacaaa gtgttcgtat cctaaaccag agtatcgatg aggataaaaa ttatgagaac
     2881 ctaataaatt atccgtgttt ggcgaataac tcatgatgtt gtcaacgtaa ttcgtgcccg
     2941 aactcatatt gatctcgatt ttgataccaa aaggattgcg cgtcattttt gcttcttctg
     3001 ctcctgtgaa tccgatatct aagcggaccc cgtaggcacc catcttatgg aaaaaagata
     3061 agtcatcgta agaaatctcc aactgttcaa ataacgctgg attgatatca accattactt
     3121 ccatgcctag gctattcgcg taatcaacta cttctttaaa ttctgaaaga actttttctt
     3181 tatcatcatt gatctgcagc aaactggtaa aaacccgttt atacccatac ttatgagcta
     3241 aatccaagta cgctttgtcc ttttcaaatg ttgaccgttc tggataaatc gagattccta
     3301 attttcccat attaccattt cctcctgcat cttttcgttt ttgtatccac ttacattata
     3361 gcaaacacaa agtaaatggt ctacaccttt tctttttctt ttaaaataaa tgataaattc
     3421 caataattta agtaggtatt ttccc
//
LOCUS       DACCVZ010000158         3406 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.162, whole genome shotgun sequence.
ACCESSION   DACCVZ010000158 DACCVZ010000000
VERSION     DACCVZ010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.162"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(89..1174)
                     /gene="xerS"
                     /locus_tag="IVW63_002842"
     CDS             complement(89..1174)
                     /gene="xerS"
                     /locus_tag="IVW63_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HAP7861060.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(2495..2917)
                     /locus_tag="IVW63_002843"
                     /pseudo
     CDS             complement(2495..2917)
                     /locus_tag="IVW63_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752995.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            2962..3129
                     /locus_tag="IVW63_002844"
     CDS             2962..3129
                     /locus_tag="IVW63_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861061.1"
                     /translation="MSIREIVRIQSFPDSYIFVGSSLSAKYKVIGNAVLPKLAKVIGD
                     SIVKQLSESNF"
BASE COUNT         1117 a          496 c          543 g         1250 t
ORIGIN      
        1 taaaaatgat aatgaagctt gcctttaaag ttgggctttt atctaatttt agagacaggc
       61 ttcattatta tactattttt tactacattt acaaagcgtt caaagcatca attgtagctg
      121 cattgtctat atgagtatat aaagttgttg tatttgtact tgtatgtccc aattgttggg
      181 cagttaatac caatgaattt gtctgttgat agagtctagt agccaaagta tgacgtaatt
      241 tatgtggact gacttggact ctgaatcctt ttgaatattt tgctaccatc cgttcgattg
      301 caataccgga tatacgcttg gcttctcctt gataaattgc tagaaataaa gctttttcgt
      361 tttctgttac tttgtatcgt tctttccgaa tagctagata attagctaaa tattccattg
      421 caaatgctgc tatatttact gcgtctctct tatttccttt tctagttact accacattat
      481 tcttttctaa agataggtcc tctaaattaa tatttacaac ctcggagagt cttaatccag
      541 atcctaaaat caatgcattg atcgccaggt ctctttctac atctcgttga taatagatca
      601 aagctcgttt gctcaaagtt tttttatatt cattggcaat ataatctaga taattttgtg
      661 tatcttcgtc tagaaataat tttttctcga ttgcgtttgc acgggcagct aacgtagttt
      721 tatctgtgat agttgctact tgatccatag gattattttc taagtatggt tttcctaaag
      781 gattattgga acttttcgaa agatatttaa atagaacctt taatgctgtg atatttctat
      841 tgatagtaga agtagataga cctaagttat tattatcttt gagcttagtt tttgttgtct
      901 ctttttttac attttccttt gtgcgacgtt tcaaatgaga tttgtacaag tttagatcat
      961 aggcagttaa ctgtcttatc gaggtgattg aagtatcggg aacgatagac tcactcagaa
     1021 gccattcata aaagagctta taatttttta gatattctaa agtagttcga ggtgattgat
     1081 ctttatcctc acgatcttga acaaaatctt ttatataatc gggcatatga agtatgattg
     1141 tatctatttt ttgatatatt tctgtatttt tcatgttatt catcctttcg ataagtaggg
     1201 gagaggagta tctctataat tggactatac caattataga gtgttttgtc aattggtata
     1261 ctctgaaatt tattaattta tttcaaaaaa gcagataaat aggtatagat ttaataattt
     1321 aaaataaatg gtatacatga ataggaaagg aaacagaagg aggcaatctt aattttttaa
     1381 attgtctaaa ttatatagaa agaacaatct ttctatataa ttagacataa gagagactac
     1441 ggttgatttg atattaacaa gcgtatatga atgtatatac aaataaaaaa ggggagggag
     1501 aagttaaaga aaattcagag aagtggggca ctcagtagta ttaacaattt aaaaggaatt
     1561 tcttaaagaa aatgggttgc atcctggaga tacaattttt ttagataaag aaaaaattca
     1621 agcaacaatt caaaaaaatc ttaactgctg agattgatgt agcaatatct caatcatcaa
     1681 caaagtacga tcctgccttt caaaagctta ttgataaatg tttattcatt ataaaaataa
     1741 aagaaaaatt tatgtcagct tttttcatca aagtggtaat gataattcgt ctattaattg
     1801 tattttttag gaaatatggt ataattgttt taacgaaaag gtaattcatg atacaccaaa
     1861 aaccactagc tggcgggcta gtggttttct tttacgttct attcagatta acgggtaggc
     1921 ttactgtctt ttttggcaat aattttgcaa tcaagccatt tacagatgta atgcgcggat
     1981 acttctgcta agattgcaaa aaacatatcg aaaaggtaat tcataataca acctcctccc
     2041 cttgccataa taggccgggg tagcagacag cataaatatt ataccataac tgaaaatttc
     2101 attttagtac atttcaatat attgatgaac cagcacaata aaacatgcca tgactaacag
     2161 aaaaaaactt attaaaccag atataacttg taaacatcca actatataga aaacgtaaat
     2221 tttctatata cttggatatg ctggaatgtt taagagaata attacatttc tagaaaatac
     2281 aataaaaatt acaggataat tagccatatc ctacctcctc tagcagttgc tcaaaagtta
     2341 gcactaagta acttcttttt tgttgctggt aacaatttat caatactaaa atagctttta
     2401 agtatctaat aaatactaat tttaaagctc ttaattatta tgaggtagcg tcaagaatta
     2461 tgtgtaaatg gaaaatccat tctgttaatt acagttaaat catcgactct aatgtatctt
     2521 gaatttcttt aaatcttttg tgaactctac ttaaaaattt ctggttatat tagttgaatt
     2581 gcgaagctaa gaatctctag agagattctt cattagggaa ttgttctttt cttcgagtat
     2641 atcgttttag ctgcttatta aagccttcaa tcaggttcgt tgaataaatt gttcgtctga
     2701 tagcgtaagg gaaattataa aaggttaata gggcaggatt caagagtagg ttcacgactc
     2761 ttcgatcctg ctttttccat ttcctaatca taaaatcgat gtaattcaat gcctcttctt
     2821 ttgaattcgc atggtaaatc aatttgaact cctcacagat ttcttttcga cctcgaacac
     2881 gcactctatg agcgatattt ctagttgact atatacatca gtattctctt tttgtaccca
     2941 tttttttgag ttcatctaag agtgtcgata agagagatag tgagaattca gtcatttcca
     3001 gatagttata tttttgtcgg tagctctctt tcagcaaaat ataaagtaat tggtaatgct
     3061 gttctaccaa aacttgcaaa agtaattggt gattctatag ttaaacaact ttctgaatca
     3121 aacttttagc tgaacacgct ttttttagat gcttttttat taagagttaa attgctttac
     3181 agatccaggt tatgttaata atgattaaaa ttttattgcc aattttataa actcgtggtg
     3241 ctagttaatt attgaatcta ggaacaagag cataatatca ctatttttac ttttgaaatt
     3301 ttactcagaa attctgtttt tagtcgtttt tataaaatga aaatgttggt ttataataag
     3361 ctgaaattaa ctagcaccac gagtctatat ccatataaga taagta
//
LOCUS       DACCVZ010000159         3358 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.163, whole genome shotgun sequence.
ACCESSION   DACCVZ010000159 DACCVZ010000000
VERSION     DACCVZ010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.163"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(224..454)
                     /locus_tag="IVW63_002845"
     CDS             complement(224..454)
                     /locus_tag="IVW63_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861062.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(890..1456)
                     /locus_tag="IVW63_002846"
     CDS             complement(890..1456)
                     /locus_tag="IVW63_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP7861063.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1456..2412)
                     /locus_tag="IVW63_002847"
     CDS             complement(1456..2412)
                     /locus_tag="IVW63_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAP7861064.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2412..3068)
                     /locus_tag="IVW63_002848"
     CDS             complement(2412..3068)
                     /locus_tag="IVW63_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAP7861065.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
BASE COUNT         1070 a          647 c          579 g         1062 t
ORIGIN      
        1 tcagtcacga tatcaaacaa aaaatatacg tctttcttca ttctagtttt cgcagcaggg
       61 attttaaagt agttcttatt agaatagtag agattaatta ataagctatc ttcgattgct
      121 aaaaagaaaa cttctgaatc ccacacctta taaaaatctt tgacaaatct attcgaagga
      181 tcaaatttaa accataattg cgtctcatta aaaagcataa ccattactcc gatctatttt
      241 taaacttagt ctctacctct aatatatatc gagtttttat tttgccttca gagaatactg
      301 tttctttttt tgcagttaca ggttgtttat tttcggaaaa agctaatata gctaaaattg
      361 aaacatccat ctggaattta tcttttttac tgctttgatc ataaaagtct gcatattcat
      421 cactgatatt ttttctaata aattcttcca tcataaaaat cacctcaaaa cgattatacg
      481 aacttacgtt cttgttgtaa agcgatattt gaggggcaaa aaaggggcat aatttgactg
      541 atattaagtt agctattgat atatgaatga catacaaaaa tataaaatct tttaaaaatg
      601 cttatatatc aatgtttttg ccattctttt atatatctgt tatatgtcaa aaaaatgtgt
      661 tcaatttcaa tttgtatttg aataaagagg ttgtgaaaaa gctgtcctgc atcaagtaat
      721 aagaacagcc aatcaaaaac agcttctcat gtttttgatt tggttggact tattaccgca
      781 gatataagct tttgagcacc gtgaataaag aggttatgaa atcaacgctc taacctgagt
      841 attagagaaa aaaacgcaaa acatatcatt tatgttttgc gttttttatt tatctttttt
      901 tctcaataca atataaaata ggcggctggt tcttttggtt gataaaccga taattcagca
      961 cattatatgt ttcctgtggc agtttggaac aaaaagaatc aaccatatcc agttcttttt
     1021 ctccaccttc atgaccatag tagacgacaa ggatcaatcg tccgcgaggc acaagtcgtt
     1081 tcaatatttc ttccatagct gtgcgtgtag tctctggcat agtgatgatt gctttatcac
     1141 tttttgggag ataccctaga ttgaaaatcc ctgctttgag attttgttgt tcagctatca
     1201 cttctcctaa cgtttcgtgg ccttgtagaa acaatgagac acgttcttct aactgacgct
     1261 gttctagcct ttcacgagta gcatcgattg cttgttgctg gatatcaaaa ctatagacat
     1321 gaccagtttt tccgatgtgt tctgctagaa aaaccgtatc gtggccattg cccatcgttg
     1381 catctacgac gtgatcccct ggttgcaaga tttcttgcag taatgtatgg ctgaaatgca
     1441 aagcagtttg caacatcaga cgctcacctt tttccgtaca tcatattttc cttggaagct
     1501 atctctgcga agaagttctt catcaattgc attcaagact tcccattttt tcaagctcca
     1561 cattggtcca atcaaggaat cccacggcgc atcccctgtc aaacgatgga tgatgatctc
     1621 ttttggtatc atttccagct ggtcgcaaat gacattgaca tagtcaggac ggctcattaa
     1681 ttgaaggcga ccttcatgat agtcccgcaa cattctcgtt ttgcgcatca gatgcatcaa
     1741 atggagcttg attccttgga tatctgaatc taaaatggtg cgtctgacat tttctttcat
     1801 catttctaaa ctttcgcctg gtaatccgtt gatcaaatgc gtacaaacac ggatattatg
     1861 tttgcgtaat ttagccacgc catctaaata agtttgataa tcatgtgctc ggttgatcag
     1921 ttttgaagtt tcttcaaaag ttgtttgcaa tccaagttct acccataaat acatccgctc
     1981 gttcagttca gcaaggtaat caactacttc atctggcaga caatccggtc gtgtaccgac
     2041 tgataatcct acgacacctg gtaaattgac tacttgctca aatcgttctt tgattatttc
     2101 aactggcgca tgggtgtttg taaaattttg gaaataaacg atgtattgtt ggacatgagg
     2161 ccatttttga tgcatcatgt cgatttcttt ctggaattgg attggaagag ggtcttcagg
     2221 tgcaacgatc atgtctcccg aaccagatac actgcaaaaa gtacaaccgc catgggcaac
     2281 agtcccatct cgattcggac agtcaaatcc tccatcgatc ggcaccttga aaattttccc
     2341 gccaaactca tttcgtaaag cgtaattcca agaatgatat cttttatttc cttctgaata
     2401 aggaaaagtc attaaaagtc cttctttctg taagagttat ctatttgttt tcttttttct
     2461 ctatacactg gataagtcag gcacagccaa gaaagactga gtaagtagcc gccgatgata
     2521 tcagtaggaa aatgaacgcc cagataaatg cggcttatcc cgacacttac tataataaac
     2581 atcatcagca attgaagcaa tgtgcgtaag gttctttttt gaacaaaagc tggaagcaga
     2641 aatagtaaag aaccgtaaag aatcatactg cctgctgcat gtccactagg gaaactgtaa
     2701 cttgtttcaa ctactaagtg cgccaatgaa ggacgctctc gcatgaaaaa tagtttgatc
     2761 accgggttga tgattccagc aattacaata aatccagaaa cgaaccaaaa tgtttctgcc
     2821 ctttttttct tataccacat ccataaagcc gcacaagcaa ataaaatgat gacggtaaga
     2881 ggattaccga atttagtcat aaagagttgg tagctgttca gatcaggata agaagctctg
     2941 acaatgcctg taaaccactg atcgaaacca gaaagccacg acagatggaa ctttacgatc
     3001 cagcccaaaa tgaaaaacag gacaagaaag aagctaccag ccacctgaaa tgatgtttta
     3061 tatttcatac aattcctcct ttgaagcaat gacttattat agcatttttg gtccagcgaa
     3121 aaaaacggta aagagataaa accaatgtat gattcctctt tgaataacca atattcttat
     3181 aaaaaaaata actgtaatcg gaaagacatt ttttggtaat gcaaatgaaa tgttagggaa
     3241 ataaaatcag tgtttttcga aatcctttta aacaagaacg tagacgtagg aagaacttga
     3301 aaatgaacag aagttgttca ttacggtaaa ttacaatatg attacaaaaa acaacaaa
//
LOCUS       DACCVZ010000160         3354 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.164, whole genome shotgun sequence.
ACCESSION   DACCVZ010000160 DACCVZ010000000
VERSION     DACCVZ010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.164"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..190
                     /locus_tag="IVW63_002849"
     CDS             <1..190
                     /locus_tag="IVW63_002849"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861066.1"
                     /translation="DLEKLTKQRDMKNFNNCVVLIIITELTLFTNIYYIHEAQSSLIE
                     DWAIFMAKEGKEMFQNKG"
     gene            212..478
                     /locus_tag="IVW63_002850"
     CDS             212..478
                     /locus_tag="IVW63_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAP7861067.1"
                     /translation="MDSLPVELQALCWNLIDQNVQKQFPLDYLQIFEFSTEKGNQKLV
                     HRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY"
     gene            505..804
                     /locus_tag="IVW63_002851"
     CDS             505..804
                     /locus_tag="IVW63_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HAP7861068.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            978..1529
                     /locus_tag="IVW63_002852"
     CDS             978..1529
                     /locus_tag="IVW63_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HAP7861069.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            1675..1968
                     /locus_tag="IVW63_002853"
     CDS             1675..1968
                     /locus_tag="IVW63_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861070.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            1961..2257
                     /locus_tag="IVW63_002854"
     CDS             1961..2257
                     /locus_tag="IVW63_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861071.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            2332..3330
                     /locus_tag="IVW63_002855"
     CDS             2332..3330
                     /locus_tag="IVW63_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAP7861072.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
BASE COUNT         1262 a          459 c          664 g          969 t
ORIGIN      
        1 agatttagaa aaacttacta aacaaagaga tatgaaaaac tttaataatt gtgtagtttt
       61 gataattata actgaattaa ctttatttac aaatatatat tatatccatg aagcccaatc
      121 ttctttaata gaagattggg ctatttttat ggcaaaggag ggaaaagaaa tgtttcaaaa
      181 taaaggataa cgttatgtca caaagggagt aatggacagt ttgccggtgg aattacaagc
      241 tttatgttgg aatctaatcg atcaaaacgt tcaaaagcaa tttcctttag actatcttca
      301 aatttttgaa ttttctacgg aaaaaggaaa tcaaaagttg gttcatcgtc aagaagaacc
      361 ggaagaaaga aaagagtatc tgatttcacc taagcttcgt ttgaaatcag tgtctcaaaa
      421 aatatgggcc attgattcgg gtgagtatca aacgatgtta ttaccagaag aatactagta
      481 tctaaaagaa aggaacgaaa ggacttgtta gaaacggcta tcgaagtact ggaaaagtgt
      541 gcacagctgg tcactgcttc tgaagagtgg ggctatgaat ccgttacgat ggaaaaagag
      601 gaaattgaaa tgggtatgct tcctgaagat gttcatctac cacgtttagt gatgacacat
      661 ctttatattt attgcgcacc agaagatgga aaagactatg tagtttattt cattacagat
      721 attaccagcc agcgagaatt tgttcgtggg ttactggtag aaggacgatt ggtttggagt
      781 cagattggag gaacggatga ataagatcga ttatttgaga atgattgcga aatgtttaga
      841 agatatcctt accgcgattc atcaaattct gaagaaaaaa ggagaaagaa tatgaaatat
      901 tttcaactag tattgacact tataacggca atggtaattg aagtgcttga acaaaaaata
      961 gcataggaga aaaagagatg attgaaaaag aattagtgac cacacaaaca gaagtttggc
     1021 gagatcctca tcatacccat cgctatgttt tcaaacgaca atgggcgatc aaaggaaaag
     1081 aagcggaaga taaattagca gtagtcatta ctattcgtcc aacagataca gaaccattta
     1141 cgaatgattt gagtatgtta ttaatcgaaa agaatatccg acaattagga tttactggtt
     1201 ttattgctgt gaatcttttt tcgtacacaa aagcgaaaag tcctcgggta tttcttcgag
     1261 gaaatgatga acaatctttg gaaatattaa cgactgtttt tacagaaaag aaaatcaata
     1321 ccattatttt tgcttgtggt tcgattacag cgacgagtca agtggcttat gaacaagcaa
     1381 agactattta cgatcaattg agtgcgaaac aaaagaagat gaccaaagta ttgataaatg
     1441 cagaaggtaa gttatcccac ccactaagta ttcatgttcg taatgaatgg caattggcag
     1501 atagtcaatt attatttcaa gaaaaataac attttatttt ctcatgttac ttataagtag
     1561 ttttacatgc tttttgactt taaaaataca tgtgatgata catgttatat gaattatcaa
     1621 tgtacccagt aatatgctat tttcattatg taaaaaataa cagggggtgt gtagatggag
     1681 attgatgaaa cttgtttgag taactcttat aaaagtatga atgacttttt tgaggaaatg
     1741 gaactggatt cagaattgct ctatcaattt tatcttgctt ttcgagggca acagatttct
     1801 tttccaatga aaatgtacga tcgtgagtta gttagaaaaa gaatcgaaaa catgatagaa
     1861 caggaaaaaa ctgtagatat ccgtcaattg acagaagttt atggtttctc tgcaagatgg
     1921 attcaaaaag taattaaaca aaaagaaagg agacgagtac atggctaagc tgattgtatt
     1981 aggtggttta atttacggtg gatattggtt atatcaatat atgcttgcgc atccgaatat
     2041 agataaagga aaagtaatta agacagttgg ggtaatcata gttggactca tagctctaac
     2101 taagaaaaat aatactaata gcccaaaaat aatgagaact tatcgctgta gaggatgtgg
     2161 aagggaaatt tctactagtt ttaatccatc tgagagtcct caaggaagag accgctgcca
     2221 tacgggctat cgacattatt gggaaagaat cgattaaaag attaccattt agatcaatta
     2281 attgtctgat agaataagta cgtgagggag aaattgaaag ggggaaatat aatgaaaaaa
     2341 tggctgttat tactaatagg aatgggaatt ttattcactg gttgtacatc tgagaatacg
     2401 aggactaaag cgactataga aactgataca acaattgaga ctaaaaaaag taaaacgcaa
     2461 tcaactgaac aaactacaac agaaatgaag caatctgtgg aaacaagtgc aagttcaatc
     2521 actgaatctt cttctgaaga ggttaagaat actttgtggg atacgaataa agcttccaaa
     2581 ttagaaactt ttgtcacaca atggggaaag acattaggtc aagaatataa aagctacaat
     2641 cttcagaata atgtaagtct gtatggcact cctttaccac aagccgtgat taatggcgat
     2701 tggaaaatgg caatcaatga agcaccagtt accgtacaat ggtcagaaga tggaactggt
     2761 catgcagatt tcaatttagt agcagtttat tctgatgtag aaactggaga atatttaggg
     2821 cagcatgttt actttttcgg ttttcaaaat ggacaaccta aagtttattt aacgcaacaa
     2881 aatcaaggta atgaaaataa ttatctgtac tttaacgaaa ctcaaaatca acagttaaaa
     2941 caaggtttca gtgatattgt gaatggacaa actcctcaaa caccagtagt agaagaatct
     3001 actcaacaag caacaactac aacgacacaa tctacaagta gttcaggaat ttcaagttgg
     3061 gaagctgcta aagaatctgt gctaaataat aaagctttat ggttgtatga ttctcctgat
     3121 aaaaatgtat caaatactaa tttaattagc acaaatgaat atatgaaaga tctaatgcaa
     3181 gatgaaaatg gaagctacta ttcaattaat attgtaacgg atgatgatgg aaacacgacc
     3241 atggctggtg gaaaacaatt tcgtgtttat acagatggaa gaatttctca acgtattgga
     3301 atgactaaca attttcaaat gattaaataa ttgaaaatat tatttatcaa agaa
//
LOCUS       DACCVZ010000161         3257 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.165, whole genome shotgun sequence.
ACCESSION   DACCVZ010000161 DACCVZ010000000
VERSION     DACCVZ010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.165"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(365..1156)
                     /gene="msrA"
                     /locus_tag="IVW63_002856"
     CDS             complement(365..1156)
                     /gene="msrA"
                     /locus_tag="IVW63_002856"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP7861073.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
     gene            complement(1347..1982)
                     /locus_tag="IVW63_002857"
     CDS             complement(1347..1982)
                     /locus_tag="IVW63_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAP7861074.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            2386..>3257
                     /locus_tag="IVW63_002858"
     CDS             2386..>3257
                     /locus_tag="IVW63_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP7861075.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTT"
BASE COUNT         1045 a          668 c          544 g         1000 t
ORIGIN      
        1 tagttattgt ttgcgctttt atacggaatt tagttcatca ttaatgtgga attcgattag
       61 gtgtctatta attatcaaga tgattctcta caaaattcca tagaaaaatc aagattctac
      121 aattcgaatt ctctttcaca tggaaataaa ggctagtaaa aaaacaggag ttgtgacaaa
      181 agacttgtca tacctcctgt ttccttgcga cttgaagctg aatgctttgc gccacaacct
      241 tttcctcggt gttctcaaag caactcctcg aaataattca taactgtcca aaaatatgaa
      301 aagctatttt tgtcagttgc tcattatttt gtcggagctg aacgctttgc gccacaacct
      361 tcctctatct atgtcgctga aaaaataaat gaagctgatg cgaatgcttg atctttttat
      421 atcttttagg ttgcttctga taaaattgtt gatgatgatt ttcagctggc caaaaagtct
      481 ttgcttggcg aatctctgta acgataggac ggctaaatcg gttagattga atcagttgtt
      541 ctcttgattt ttcagccaat tgcctttgct tttcattaac aacaaataga attgaacgat
      601 attgtttccc ccgatcttga aattgaccaa aggcatctgt agggtctgaa atttgccaat
      661 aaatctccaa cagctcttca taggttattt gacgtgtatc aaatatgatc tcaacagctt
      721 caacatgccc agtatatcca ccactgactt gatcgtaatt tggttttttg gtctctccac
      781 ctgtataacc agataacact gagattacac ctggttttgt ttcaaaaggc tcaaccatac
      841 accagaaaca gccaccggca aaaatcgccc gttcttggta taagggtgaa gttatcttat
      901 gtttggcata atcataagcc tttgcactcg ctgactcccc tgtgattctt aaataaaaat
      961 ccatcgcatc tggtgtcaaa ttatctcgta gtgctagcgg acgcaagttg acctctagtt
     1021 tttctatcac ctgctttatc gacatttttg ctaggtcttc ttttgcctct tcaaattgtg
     1081 ttctttccca ttctcttgta tttcgattta aaataatatt ataaaggtct atttccatct
     1141 gctccacatc taacatgaag tcaccctctt tcaagttttc ttcttattca ttcaaaaaat
     1201 gactacctga aatttagcac aacgcataac aagttaagac taacttgctt ttcgctctcc
     1261 tcatctctat tcttagtcga acacatccac acgaatggtt acccatagag aaattctttt
     1321 acttaatcag cttcacactg ctttttctac tttcgtagtt gaaaaaaact taaacaaatc
     1381 atcggcaaat agttaaagaa aaaacttaag cgttgaaaga agcccaattg cttaaagaag
     1441 gcaaactgac taatcgacgg aatccgtgct aatccgtaaa gacctgcaat tagtaaacta
     1501 ataactgtta aaacaagata aaaatggcta agcgtacctt gaccactttg acgataaagc
     1561 agaacaagta acaatgggaa aagtagaaag cctgcatagc ctagcccaga acctatatta
     1621 tggatccaag tcgatagatt ccaagagctt tcattcgtat tgatactgaa taacccagta
     1681 aaaatacaat cacctatccc atataaacca actgttgcaa cagcaagtat tgcaagtgtt
     1741 tttgatgttc caataaatag gtgatacaac gcaggcaacg aaagaacaaa aaaaagtcca
     1801 gatacaactg accagaccaa gaaagcacgt ctgactggac tatctacgtc accaaacaca
     1861 ctaattacgg tagtcatttg attcagtttg ggataaaaaa ggccaaggat atacggtgtc
     1921 gataaatcac taatcacacc taataataaa aaataaaaac catatttttg caaaaaaatc
     1981 attttcttct cctacttttt agtgattatt cgatacatcc aacaatcaaa ttttttctca
     2041 ttttaacaca tatttttatt ctagttgcct tttgaacaat caataacata aaggtgagtt
     2101 tcttctacat tttaaaaaat cgaatggcac tgaagagttc agttgtcagc atcaatctcc
     2161 tactcaaaaa ggcaaaaaaa cgtaagtcag atgttgttga catctcactt acgcatccat
     2221 tgattgaaaa tttcttagta aaatcggttc tataatattt tgtgttggtg gaaaatcgaa
     2281 agcgattttc tactaacact tttttcttcg tttcaactca aaaagagact cacttttggt
     2341 aaaatttagt cgaccaaaac gtcaccctac caaaggagtc tctcaatgga taatcatact
     2401 agaaaattac tcggattaac agataaacat ttattttttg atgaagaatg gctgattgaa
     2461 aaagaatata aaggcgttca agcgcagttt attaaaggga gattggatga ctcaccttcc
     2521 cattgtgaac actgtggatc gattcgtatt atccgcaacg gttcctatac gacacgcact
     2581 cagatgttga aagtcaaaga aaagttgact attttagaat taaaacgtac ccgttttctc
     2641 tgccatgatt gtggacggac cttttctgcg aaaacggact tagttgatga acatcatcaa
     2701 ctaacaaagg aactgaagca ggcgattctc atggaactgt acgaaaatca atcacgtaaa
     2761 ctaatcgcta agaagtactt cgtctcggat gggacggtga cacggatctt gcgtgaagca
     2821 acgaagcatt accagccacg tatgaacttc cttccgacgg tgttgtgtat ggatgagttc
     2881 aaatcaatga agtctgtttc tggttccatg agttttattt gtgttgatgg gacaaccaat
     2941 cagctattta cgatccttga agatcgcaga ctttacaaac taactcaata cttcctgcgc
     3001 tttcctagaa aggcccgttt aaaggtcaag tacctagtga tggacatgaa tgccagctat
     3061 tgtcagttgc ttaaaacagt ctttccaaat gcggagatcg taactgaccg ctttcatatt
     3121 gtccaacaca tcaatcgcag cttcaatcaa ttacgtgtcc agatcatgaa tcgttttcga
     3181 acctcacact ctgaaaatca gaagaagtac cgtcggctca agcgatattg gaaactctta
     3241 ctcaaagatt ccacgac
//
LOCUS       DACCVZ010000162         3242 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.166, whole genome shotgun sequence.
ACCESSION   DACCVZ010000162 DACCVZ010000000
VERSION     DACCVZ010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.166"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(553..2166)
                     /locus_tag="IVW63_002859"
     CDS             complement(553..2166)
                     /locus_tag="IVW63_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HAP7861076.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2307..3215)
                     /locus_tag="IVW63_002860"
     CDS             complement(2307..3215)
                     /locus_tag="IVW63_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7861077.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
BASE COUNT         1045 a          557 c          573 g         1067 t
ORIGIN      
        1 gttaaataaa taggaacaaa aaaattaaat tatttaatac acacattagg gatcattcat
       61 tgaaggatta gaagacaacg aggatggcga aaaatatgat tacaatagaa aagtcgttct
      121 aaaccaatca gttcctagta tcacacaacg caagccagtc gatttggtga gattagagga
      181 gtgaaagcaa actttattat ataagaaaaa atattcgaaa gggatgctag tttaggtact
      241 agtgctgata gattaatatg atgcctcgta atattaggcg tagttactct agagacatca
      301 ctatggacta tgatttgtct cagagtcaca acatgttttt ttatgaaaag aaacagctaa
      361 aataattaaa ttgcgcaatg tttaaacttt cttaaactat aacctaataa atgtgaagaa
      421 ataatgcaca atttcttcac atttatcttc tattctatat acataccaac caacaaccct
      481 atatactttt tcatttttac tcctcaagta aaaataactc ctagaccgcg gctacccacc
      541 gcggtcgttt ttttattctt caatcaaaat cgctttgata cccaaacctg ccaagattcg
      601 ggcagaagta taagtattca atcctcttct gaaagtaatg taaacttttt tatcttttgg
      661 gatttcattg attcgatctc gtaactcatt cattggaata ttttttgttg ccgagatact
      721 gccagaaggt gctttattag gttcacgtat atctaaaaag aacgcttctt tcaaatcgtt
      781 ttcgggtata tcacttgctt tgatcgtttc tacgatattc gtcatttgat tgattgcgac
      841 ataaccagct atattcaacg ggtcacgggt agtagaatac ggtggagagt aaggcaactc
      901 caaatcaggc aaatcaaaga ctgtcaagtt tccggtgatt gctacagaaa gttctcccat
      961 ccgtttatcg acaccttttt ctccaaatgc ttgtccacct aaaatacgac cgctatctgc
     1021 atcaaaaatc agctttagat ttaatcttgt agcttctgga tagaaatagg catggtcaaa
     1081 gggagtgata aaaacagttt tataatttgt tatgcctgat gcttttaatt catgttctgt
     1141 cattcccgca taacttgctg tatgatcaaa gatttttgcg acacctgcac caatatatcc
     1201 gcgatagcgc ataggcgtac catttaaaat atctgccagc atatgtcctt gacgattggc
     1261 cgcactggaa agcatacttt ggatcggctg accagtcact acactagtcg tttcgataat
     1321 atcgccaatc gcatagatgt ccggcagatt ggtttgtaac tggtcatcaa caatgatctg
     1381 acctgtatct gataattgta tgccggttgc tttcaccact tcattcttcg gagaaacacc
     1441 aacagcaaaa attagcatat cagcagaaag gacggagcca tctgataata ctatttctcg
     1501 acctttatca cggatctcag taactcttgt ttctaaatga acggctaatc cttctttcag
     1561 caatttgtca taaactaaat tagcaatttc tggatcataa gggaaagcga cttgtggcaa
     1621 ttgatcgatt aaagtcacgt ctaagccgcg atgcttgaaa ttctcagcta attccagacc
     1681 cataacacct gcaccaagaa tgacgacatg ttgtggattt ttttcttcaa ggaacgattt
     1741 gattcgatcc gcatccgtca cactacggag gacaaagccg ttttctgctt caaaaactcc
     1801 gggaatatcc ggataatctg gtctagcacc agaagagatg atcaacttat cgtaatctgt
     1861 ttttatttct tcatttgtgg ataggtcttt aactgttaat cgcttagtag aaggatcgat
     1921 tgctgttact tcgtgtttag taaagacatc gatgttgttt tttgttttca atatttctgg
     1981 tgtacgttcg atcagcgagt cacggtcagt gatcacacct cctaaataat aaggcaaagc
     2041 acaacttgca taagaaatat tttctccgcg ttcatagata atgatttcgt gcgcttcatt
     2101 caatcgacgg aaacgagtgg caaatgaagg accgccagct acaccgccaa tgacaacaac
     2161 tttcataaaa acatctcctt ttctacgttg atcgtactat gttatggtaa aaaacagcaa
     2221 ataattgtgc cggaaaatta ttgtttattt tgaatagaca gaaaatatag agaaataatt
     2281 tgtggataaa acctaaaaat ttttttctat tttaaggata gataatactt tgaaggggat
     2341 aaccctgtat attttttaaa agctgaagaa aaatgatgga tcgaatgaaa tcctaatata
     2401 tctgcaattt ctgtataggt taattcattt tctagcacga gacgttttgc tttttccatt
     2461 tttagttctt taaaatagct aataacactt tttccattca cttttctaaa atgttttttt
     2521 aagctggctg gactgataaa aaaaatttgg gctaattgtt caagcaaaaa attttctgaa
     2581 agatgttctt ctaaatatcg tatgattgga tcaactaatt catctgaata aagaatatgc
     2641 ttttttttag gaatgacttt ctcatttgaa ggtattgtca ataaagcaag ttcctgttga
     2701 taatgccttg gtaaggaaga caattgaatt ttttgcagac aataagtaac taataaggaa
     2761 agcaaatgaa tgctcatctg ttggcatagt atgaaaaaag aattgatttc ctgatcatag
     2821 gaaatagctg gcttactatg ttttagataa tcaattttga actgttcatt tttcagaaaa
     2881 gtaatgatag atgttatttc ttgatctata gaaaaagatt gtcccgtaat atgtgctaat
     2941 aattgctcat caaaataaaa ctggataatg ataaaagttt gtgtttcctt ttgagtagaa
     3001 aagatttgga cttcttgctg tttatcaatg aataaaaggg aaggattatc tagttctata
     3061 gatttatgtg caaattcagc atataaatta gcgctttcat ttattagtag tcgaaaatag
     3121 ggagcagcag ataaatgaag atgggtatct atggaatagg ttagtgtttt tttgacaaga
     3181 ttggaggatt ggttgtttgt taacaaaaga accactttcc tttctctttt tatataaaaa
     3241 gc
//
LOCUS       DACCVZ010000163         3207 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.167, whole genome shotgun sequence.
ACCESSION   DACCVZ010000163 DACCVZ010000000
VERSION     DACCVZ010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.167"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            134..736
                     /locus_tag="IVW63_002861"
     CDS             134..736
                     /locus_tag="IVW63_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861078.1"
                     /translation="MEDIILRDRLTDPLKNSLANVIYDILREADKVYSNYNGKVSWVI
                     YSFLIKEFFKEQINNSYELGYHFTVYYEDIIKRLEDLEWYAYYDLLEVFASAKILDKK
                     KREEVNKILESENSGYRLSESNEFIPITDDISIKSINAVSESPFNYAKNHIHKSLTYI
                     SEKENQDYNTVVREAISAVESCLIEFSGLPANKKILWELL"
     gene            1091..1327
                     /locus_tag="IVW63_002862"
     CDS             1091..1327
                     /locus_tag="IVW63_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003125429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HAP7861079.1"
                     /translation="MNIKKRKIREVGNSIVVTLSKESLLQKGLKPGDTIFIDEDKMME
                     AIVKEESKIDLEIDMYVNQALSEYDAAFKELVEK"
     gene            1324..1737
                     /locus_tag="IVW63_002863"
     CDS             1324..1737
                     /locus_tag="IVW63_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAP7861080.1"
                     /translation="MIYLSEKDIVKLNVIQIKKYSPRETIGVIDKNALSMAVNQPKQH
                     IFGKDLYPDKFSKAAVLLINLIKKHPFHNANKRTAFLAAYVFLKLNGYSLKMKNQEVV
                     EFVVEIATYQGDFDDLKEATTDILKKNSTKTDSKK"
     gene            2256..3206
                     /locus_tag="IVW63_002864"
     CDS             2256..3206
                     /locus_tag="IVW63_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HAP7861081.1"
                     /translation="MERNSENKMTGRNPKVFISYSWENKENKEWARELADKLLENGID
                     AYIDQYDLSLGDRLPQFMEQQISDSDYVLIICTPEYKKKANNRTSGVGYEGHIISAEL
                     LSGKNERKFIPIIKEGRASEVLPTFLAGKLGIDLSDSQHYDENLDDLITTIFGVKRKP
                     ALGDIPRHIKGSPLLPIEHNENKDIEILGIITDKVTVPKMDGSRGSALYKIPFRLNRV
                     PSQLWKELFVRNWNSPPRYTTMHRPGIASVVDDEILLNGTTIEEVREYHRETLKLCIE
                     KSNTQEKKILLEEEQKKERENERVRSHKESVQKLADELEF"
BASE COUNT         1231 a          392 c          573 g         1011 t
ORIGIN      
        1 caatcttaac agatatttca ttttatttat gtaaaacaac acgaataatt attgcttcgt
       61 aaagttatat gagtataagt taatttactg gaggtagtgc aatgcttttt tctgaaagat
      121 ttggttttaa aaaatggagg atatcatact gagagataga ttgacagacc ctcttaaaaa
      181 tagtttagca aatgtgattt atgatatatt acgagaggct gataaagttt atagtaatta
      241 taatggaaaa gtctcatggg taatatattc ttttttaatt aaagagtttt ttaaagaaca
      301 gataaataat agctatgagt tgggttatca ttttactgtt tattatgaag atattatcaa
      361 gaggttagaa gacttggagt ggtatgctta ttatgattta ttagaggttt ttgcaagtgc
      421 taaaatcttg gataaaaaga aaagagagga agtaaataaa attctggagt cggaaaattc
      481 tggttacaga ttaagcgaaa gcaatgaatt tattccaatc acagatgata tttctattaa
      541 gtctataaat gctgtatctg aatcaccatt taattacgca aaaaatcata tccataaatc
      601 tcttacatat ataagcgaga aggaaaatca agattataat actgtagtga gagaagcaat
      661 tagtgctgtc gaaagttgtc ttatcgaatt ttcaggatta ccagctaata aaaaaatact
      721 ttgggaactg ctataaaagc aattaaagac aaatcgaata acaatgtcga tcttacattt
      781 ttaaaaccat ttgagacaat gtatggtttg gcgagtaata atggaatacg acatgcagaa
      841 aatgaaaaaa caattgtctc agatttacct gatgcagttt tggtgttaac aacatgttca
      901 gccgtaatta attatttggg agtaaaaata gcatatgact ccaataaatc atgaaaagtt
      961 aaaattcatc caagagctac attataacta ttaatttcca actctttaaa agtttagtaa
     1021 ttgaaggaag taataagggt gattgaacaa tacggatata cggtgtatac ttatcgtagg
     1081 agttgatgat atgaatatta aaaaacgcaa aatcagagaa gtaggtaatt caatagttgt
     1141 aactttgtca aaagagagtt tattgcaaaa aggtttgaaa cctggagata ctatttttat
     1201 tgatgaagat aaaatgatgg aagctattgt aaaagaggaa agcaagatag atcttgaaat
     1261 tgatatgtat gttaaccaag ctttatctga gtatgatgca gctttcaagg aattagttga
     1321 aaaatgatct atctaagtga aaaagatatt gtaaaattga atgttattca aataaagaaa
     1381 tattcaccgc gagaaacaat cggagtcatt gacaaaaatg cgctgagtat ggctgtaaat
     1441 caacctaaac agcatatttt tggaaaagat ctgtatcctg ataaatttag caaagcagct
     1501 gttctgctaa taaatctgat caaaaagcat ccatttcata atgctaacaa acgtacagca
     1561 tttttagccg cgtatgtttt tctcaagcta aatggctatt cactaaaaat gaaaaatcag
     1621 gaagtagtag aatttgtagt tgaaattgct acgtatcagg gtgattttga tgacttaaaa
     1681 gaggcaacaa cagatatact aaaaaagaat tcaacaaaga ccgattcaaa aaagtagaag
     1741 caaactaggg attcagttaa atctgaagat ttagtttgtt ctttatttta gtttacataa
     1801 gatacattat gcgaagttca ttattttaaa agcttaaata ataaactttt ttataatacc
     1861 aatttattta tgtaaaccaa tgaccttaat cgcttaagca agcatgttat gtaatactct
     1921 actctctcca aaactaatga ctatctattt tcaaagaagc tagaatgatt atctgatcaa
     1981 atgataattt atatttaatt cctggtctac tgctcttctt ttaatcaatt aatgtctaac
     2041 gtactgtaca cgataaagta ggaagactta ttttcaactt cggattcatt tttttaattc
     2101 ggtgaaaatc actaaattaa gagtttatcc aagttcattt tagctgagaa tacgcttgaa
     2161 aataattttg atgaattttc ctgaattaaa atttattaac ttgttgagtg atataattgt
     2221 aatgtattac caaatagtta gcacttagat tagtgatgga aaggaatagt gagaacaaga
     2281 tgactggtag aaatcccaaa gtatttatat catattcatg ggagaataag gaaaataaag
     2341 aatgggctag agaactagca gacaaattac ttgaaaacgg tattgatgca tatatagatc
     2401 agtatgattt aagtttaggt gatagattac ctcagtttat ggagcagcaa atatccgatt
     2461 cagattatgt tctaattata tgtacaccag agtataaaaa aaaggcaaat aatcgtacaa
     2521 gtggtgttgg gtatgaaggt catattatct cagcagaatt gctttctgga aaaaatgaac
     2581 gtaaatttat cccaataatt aaagaaggac gtgcaagcga agtacttcct acttttcttg
     2641 ctggaaagct tggaattgat ttatcagata gccagcatta tgatgaaaac ttagatgatt
     2701 taattacaac tatatttggt gttaagagaa aaccagcatt aggtgatata cctaggcata
     2761 ttaaaggcag tcctttacta cctatagaac ataatgaaaa taaagatatt gaaatcttag
     2821 gaattatcac tgataaagta actgtaccta aaatggatgg ctcaaggggt tctgcattat
     2881 ataaaattcc atttagatta aatagagtac caagtcagct ttggaaagag ttgtttgtta
     2941 gaaattggaa ttcaccacca cgatatacaa caatgcatag accaggaatt gcttctgttg
     3001 tagacgatga aattttactt aatggaacaa ctattgagga agtccgggaa tatcatcggg
     3061 aaactttaaa actttgcatt gaaaaaagta atactcaaga aaaaaaaata ttgctagagg
     3121 aggaacaaaa aaaagagaga gagaatgagc gagtcagatc acataaagaa agtgttcaga
     3181 aattagcaga tgaattagag ttctagt
//
LOCUS       DACCVZ010000164         3159 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.168, whole genome shotgun sequence.
ACCESSION   DACCVZ010000164 DACCVZ010000000
VERSION     DACCVZ010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.168"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..480
                     /locus_tag="IVW63_002865"
     CDS             <1..480
                     /locus_tag="IVW63_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HAP7861082.1"
                     /translation="YNSYKKLKKSFITIEGDEKYAKFLCDFFKKLGNSTVIVSKENKS
                     LYHAASVVSSNLVLGLINTSVTYLIQCGFTEKMAIEALYPLIEFNIRNIKEKGIIESL
                     TGPVERCDISTIKGHCEVLSDEDRALYMLLSKNVLEIAMLKNINRDYSELEKYLGES"
     gene            492..1319
                     /gene="panB"
                     /locus_tag="IVW63_002866"
     CDS             492..1319
                     /gene="panB"
                     /locus_tag="IVW63_002866"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HAP7861083.1"
                     /translation="MKNTAVTFKESKLRNEKLTMLTAYDYSTAKIIDEAGINGILVGD
                     SLGMVCLGHEDTLSVTMEDMIHHTRAVTRGAKNTLVVADMPFMSYQTSVYDSVVNAGR
                     LIKEGRAQVVKLEGGIEVCDKIEAIVKASIPVMAHIGLTPQSVNAFGGFKVQGKDKEA
                     AKELIRAAKAVEKAGAFAVVLECVPTKLAELISKEISIPTIGIGAGAGCDGQILVYQD
                     MLGMYSDFTPKFVKKYANLSEEMNKAFTKYIEEVKDGVFPGPEHGFKISDDVLEKLY"
     gene            1334..2182
                     /locus_tag="IVW63_002867"
     CDS             1334..2182
                     /locus_tag="IVW63_002867"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HAP7861084.1"
                     /translation="MVIFKTVNDVRSQVKEWKKQGLKVGLVPTMGYLHEGHESLIRKA
                     SKENDKVVVSIFVNPTQFGKNEDLGSYPRDLERDIEVCTRGRATAIFNPEVEEMYCDN
                     ASTFVNITGLTEGLCGASRPIHFRGVCTVVSKLFNIIPADRAYFGEKDAQQLAVIKRM
                     VRDLNIDIDVVGCPIIREEDGLAKSSRNTYLSLEERSSATILNKSLTLAKEALNNGER
                     DSLKIIEIISKNINTYNLAKIDYVEVVDSLSLQRVNYIEKSVLVAIAVFIGKTRLIDN
                     FTFELQ"
     gene            2192..2587
                     /locus_tag="IVW63_002868"
     CDS             2192..2587
                     /locus_tag="IVW63_002868"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HAP7861085.1"
                     /translation="MKVTMLKGKIHRATVEQAELNYVGSITVDMNLLEAAGIYEYEKV
                     QIVDVNNGNRFETYTIAGERGTGMICLNGAAARCVSTGDKIILMAYCELNENEVKDHR
                     PKVVFVDDNNKVERVTSYEKHGRLSDIIL"
     gene            2789..3159
                     /locus_tag="IVW63_002869"
                     /pseudo
     CDS             2789..3159
                     /locus_tag="IVW63_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1252 a          347 c          634 g          926 t
ORIGIN      
        1 tataattcat acaaaaaatt aaaaaaatct tttataacaa ttgaaggcga tgaaaaatat
       61 gcaaagtttt tatgtgattt cttcaaaaag ttaggtaata gtactgtaat tgtatctaag
      121 gagaataaat ctctttatca tgccgcatca gtagtatcta gtaaccttgt gctaggactt
      181 attaatacaa gcgttacata tctaattcaa tgtggattta ctgaaaaaat ggcaattgaa
      241 gctttatatc cattaattga atttaatatt agaaatataa aagaaaaagg aattatagaa
      301 agtttgacag ggccagttga acgttgtgat atttcaacaa ttaaaggtca ctgtgaagtt
      361 ttatcagatg aagacagagc tttatatatg ctattatcaa aaaatgtatt agagatagct
      421 atgttaaaaa atattaatag agattatagt gaattagaaa agtatttagg agagagttag
      481 gagagaaata gatgaaaaat acagcagtta catttaaaga atctaaatta agaaatgaaa
      541 aattaacaat gcttacagct tatgactatt caacagcaaa aataattgat gaagctggga
      601 taaatggaat attagtagga gattctcttg gtatggtatg tctaggacat gaagatacac
      661 tttcagtaac aatggaagac atgattcatc atactagagc agttacaaga ggagctaaga
      721 acactttagt tgttgcagat atgccattta tgtcttatca aacttcagta tatgattcag
      781 tagttaatgc aggaagatta ataaaagaag gacgagctca ggttgttaaa ttagaaggag
      841 ggatagaagt atgcgataaa atagaggcta tagtaaaggc ttctatacct gttatggcgc
      901 atataggttt aacacctcaa tctgttaatg catttggagg atttaaggta caaggaaagg
      961 acaaggaagc tgctaaagaa ttaataagag ctgctaaagc tgtagaaaaa gcaggagcat
     1021 tcgctgtagt gttagaatgt gttccaacta agcttgcaga gttaatttct aaagagatat
     1081 caatacctac aattggtatt ggagcaggtg cagggtgtga tggacaaatt cttgtatatc
     1141 aagatatgtt ggggatgtat agtgatttta cccctaaatt tgtgaagaaa tatgctaatt
     1201 tatcagaaga gatgaataaa gcatttacaa aatatataga ggaagtaaaa gatggagttt
     1261 ttccaggtcc agaacatggg tttaaaataa gtgatgatgt tttagaaaaa ttatattaaa
     1321 agggtcaaga aatatggtta tatttaaaac agtgaatgat gttagaagtc aagtaaaaga
     1381 gtggaaaaaa caaggcttaa aggtaggatt agttcctact atgggatatt tacatgaagg
     1441 tcatgaaagt ttaattagaa aagcatcaaa agaaaatgat aaagttgttg taagtatctt
     1501 tgtaaatcca actcagtttg ggaaaaatga agatttaggt agttatccaa gagacttaga
     1561 aagagatata gaagtatgca caagaggtag agcaacagca atatttaatc ctgaagttga
     1621 agagatgtat tgtgacaatg caagtacttt tgttaatata actggattaa cagaaggttt
     1681 atgtggagct agtaggccaa tacattttag aggggtttgc actgttgtaa gtaaattatt
     1741 taacataata ccagcagata gagcttattt tggagaaaag gatgcacaac agttagctgt
     1801 aattaaaaga atggttaggg accttaatat tgatatagac gttgtagggt gtccaattat
     1861 aagggaagag gatggactag ctaaaagttc tagaaacaca tacttaagtt tagaggaaag
     1921 atcttcagct actattttaa ataaatcttt aactttagct aaggaagctt taaataatgg
     1981 agagagagac agcttaaaaa taattgagat aataagtaaa aatataaata cttataattt
     2041 ggcaaagatt gattatgtag aagttgttga ttctttatca ttacaaagag taaattatat
     2101 tgaaaaatca gttttagttg caatagcagt atttatagga aaaacaagat taatagataa
     2161 ttttacattt gaattacaat agggggctat aatgaaagtt acaatgttaa aaggaaaaat
     2221 acatagagct acagttgaac aagctgagtt aaattatgta ggaagtatta ctgttgatat
     2281 gaatttatta gaagcagcag gaatatatga atatgaaaaa gtacaaatag ttgatgttaa
     2341 taatggaaat agatttgaaa cttatacaat agctggagag agaggaacag ggatgatttg
     2401 cttgaatgga gctgcagcta gatgtgtatc aactggagat aaaataattt taatggcata
     2461 ttgtgaatta aatgaaaatg aggttaagga tcatagacct aaggttgttt ttgtcgatga
     2521 taataataaa gttgaaagag taacatcata tgaaaaacat ggaaggttat cagatataat
     2581 tctttaggtt ttgtaatgtt atttatatat agctagacta ttattgaaat atttattgat
     2641 tactaattgg atagatgtca ataaagtaga cacaaaaaga gaagatacag actgtagaca
     2701 aagtccattt tatgtgaatc ggctacacta gactagacag aaaaaataag gtgtgtagaa
     2761 taataaaaaa cacactggag gatttttcat gtcaagacgt caacgaagaa cctattcaaa
     2821 agaattcaaa caacaaatcg tcaatctcta tctcgctggt aagcctcgcg cagaaattat
     2881 tcgagagtat gagcttacgc cttcttcttt cgataaatgg atgaagcaag cacaatcaac
     2941 gggctcattc aaaaaaagag acaacttaac accagaacaa gcagaattga tcgcactaag
     3001 aaagaaaaat aagcaactcg aaatggagaa tgatatttta aagcaagcgg cgctgatatt
     3061 cggacgaaaa gacaagtaat tgatgccaac aagcataaat attccatatc agcgatgtgc
     3121 aaaattctaa atatttctcg tcagacctac tattatcaa
//
LOCUS       DACCVZ010000165         3099 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.169, whole genome shotgun sequence.
ACCESSION   DACCVZ010000165 DACCVZ010000000
VERSION     DACCVZ010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.169"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            468..2105
                     /locus_tag="IVW63_002870"
     CDS             468..2105
                     /locus_tag="IVW63_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAP7861086.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2250..2990)
                     /gene="truA"
                     /locus_tag="IVW63_002871"
     CDS             complement(2250..2990)
                     /gene="truA"
                     /locus_tag="IVW63_002871"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAP7861087.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
BASE COUNT          962 a          531 c          433 g         1173 t
ORIGIN      
        1 taatcagaat cgtacaaata tttaataacc aaatatatag aacataactt aatattaagt
       61 tatttgaaat tccataaaaa acgactgcag gaattattgt aagaaaagga taaaaatagt
      121 tcagtccatc tccataattg ttaaatgttg tatagttgat tggcccttca aaaatagaag
      181 ataacccttt gattcgtgaa agatgaaaag ataaatcacc tgttgtataa atttcttgag
      241 catttctcat aaaatttact gaatataaag tactaagtaa gataagaact actaaaagaa
      301 atgctttttt acttattttc atagatttgt tgttctcctt ttttaattct attttcagta
      361 tactagaatt gtcttttttt aataagtttt gcgttaaatt tttcatagca ctagtatgat
      421 atactagaaa agaatcaatt tttattactt ttaaatagga gaaaaaaatg aaaaaaaaca
      481 aaaaccaaat aatagatatc atttttatgt tatttctaag ttttgcttac gtcatccctc
      541 tattcatgtc tatgggaatc tatcatagtg tcaatcagga tacttacttt catttatctc
      601 gaatcatagg actagataat gtatggagtt ctccagtaaa cttcaataac ttcgatcatc
      661 atggaacaat gatgaatatt ttttatccat ggcttactct ttatccagct tttttatttt
      721 ataaaatgat gggaaatctt gttttaagtt ataatatcta ctattttttt atcacttttt
      781 taacaatggt cgtttcttat ttttctatga aacaaataaa aaacaatcgt tatatttcgc
      841 tgttattttc gattatttat acattttccg cctatcgtgc cattgacata ttccatcgtg
      901 cttcattggg agaagctgtc gctttaacat ttttgccttt gatactaatg gggtgttacg
      961 aaatttatat tagagattac caaaaatggt actggttgtc tattggcatg acgctagtag
     1021 tgtatactca tttactttct gtcgctatgg tttctgtatt tattggagga acgttgtttc
     1081 tttcttttta tttttgggac caaaaaatcg ctagactctt aagtctttta aaagctaccg
     1141 tcctcacctt ttttttaagt gcgggattct taattccttt tattcaacaa tctagagcac
     1201 aagaattgaa agtcccactg ggaaaagaat taagtggtat ggctcctagt gatatgctga
     1261 cacacatttt aaataataac tataacaact atactattgg attattctta tttctcggat
     1321 tgattggtgc ttttattttt ataaaaaaat taactgctga tgatttattt attttctttc
     1381 ttggtgtatt tgttcttttt tgttcaacca atttatttcc ttggcaactt tttaaccata
     1441 caccagttaa gagtctacaa tttgtctggc ggttaaatgg tttttcttct ttatttatag
     1501 cctatacgat gagtatagtg atctattata ttttttctac taaaaataat tcatggaaaa
     1561 taatggtctt tacgtttctt gcactaatat tgcatctctc aggagtaagc aattctatcc
     1621 atgctaacaa agattcatta acacttatag cacctgaaga cgctgttgct atagctgaaa
     1681 attacaatca tactgattat gcaaacaaag agtcaatcta tcatcctgat atgattaata
     1741 atgatcaata tttactaggt aaccaggaaa taaatccaac aactcatttt atgagtaaca
     1801 aacttacaat tgaattagat aattcgaata ataaaaatac tgtcttgacg acacctattt
     1861 atcgttataa agggcaagtg gcttctatta atggcaaact agtacaaaca aaattatcta
     1921 agtttggcac aactgaatta actattcctc caggtataaa taaagtcgtt attacttatc
     1981 agtacacaaa actagcaatt gcttcaagat atttatctat cgttactttg attttatttt
     2041 tactttatcg atttactttt tctaaacaaa aacaaccgag aagagaagta caacattctc
     2101 actagatttt tatttaagaa agacttttta gctgtacaca taaacaggct aaaaagtctt
     2161 tttttatatt tctttaattt gcttcataca ttatttaaca tcgatattta tactgtgaaa
     2221 catgcgtttc atccattatc aaagtatttt tatcgataat aaacttcatc caaaaacaga
     2281 ccttgtgcag ggacggtttc tcctgcatgt tgccgcactt tgctttcaaa tatttcatcg
     2341 attgtttcta tcggcatggc acctgtgccg atttctagta atgtccccat gataatccgc
     2401 accattttat ataagaatcc gtctccgaca aaagtaaaat gaagcatttc tccctttcgt
     2461 tcgatagata attcatcaat cgtacgcact gtggattttt ttgatttttt caatgcagaa
     2521 aaaccaatga aatcatgtgt acccactaat ttttcgcaag ctgcattcag cttgtccata
     2581 tccaactctt gagggaaata aaagctgtgg tttcgctcaa atgctgaagg aatcacgttg
     2641 ttccaaacat aatagctgta ttttttgccc accgcattat atcttgaatg gaagcgctca
     2701 ggcatttctt cgattctttt gatgacaata tcccgcggaa ggtaacgatt cataaagtcg
     2761 atcatttctg ccagtccaat ttctgtgttt gttttaaaat ttgctacttg tcctcgcgca
     2821 tgggtgccag catctgttct tcctgatcca ataatttcta tctcttcatt tgtcatctga
     2881 tgcaatactt tttcgatttt tccttgaatg gttttatcgt catctccaag tctttgccat
     2941 cctgaatatc tttttccgtc atattcgatt gtcaacttga tgtttctcat attttagtgg
     3001 ctcctctgtc ttccatttgg tcttctctct acctttttaa gattgtagca caaaatatag
     3061 ctcctttctt ctctaaaaca gaagctatac aagaaaact
//
LOCUS       DACCVZ010000166         3031 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.170, whole genome shotgun sequence.
ACCESSION   DACCVZ010000166 DACCVZ010000000
VERSION     DACCVZ010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3031
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.170"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            581..1540
                     /locus_tag="IVW63_002872"
     CDS             581..1540
                     /locus_tag="IVW63_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP7861088.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            complement(1527..2132)
                     /locus_tag="IVW63_002873"
     CDS             complement(1527..2132)
                     /locus_tag="IVW63_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861089.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNS
                     LDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKVSFVKLS"
     gene            complement(2372..>3031)
                     /gene="tnpB"
                     /locus_tag="IVW63_002874"
     CDS             complement(2372..>3031)
                     /gene="tnpB"
                     /locus_tag="IVW63_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAP7861090.1"
                     /translation="YISLLCKEEVRELPKSNSAVGIDLGIIDFAILSTGQKFDNNKFT
                     SKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEKVMNQRTDFLNK
                     LSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYKADWYGRKIIKV
                     DKWFPSSQICSNCGHKDGKKSLEIRKWTCPICHTHHDRDINASINILTEGLRLHSMGL
                     A"
BASE COUNT          988 a          504 c          471 g         1068 t
ORIGIN      
        1 aacaataaat gaagactttt ttattgttaa ttgtttattt ttctattatt agatatgaaa
       61 atcgcattta gataaaatag aaaaatatga atatatttta aatattaaga tgagagtcat
      121 taacttatga tagtagtcaa tttgcttttc actaattaca aaatatgtga tataggaagt
      181 ttagttattg ttctcataat gccatcctgt ttttagatta tctagtaatt tttttgttat
      241 ttaaaattag gagcagtgcc aattgtttta attttaaagg ctttttttat atcttctaaa
      301 ttagaagata tttgtatatc aatatggaat atattacctt ttttgtattt ttttatgtta
      361 tctttagcta aaacatcaaa tacatgtcct tgaaattgta tcgaggcagc tggatttagt
      421 ttaaattgag gaaactttac cacagctgat tcaaaacact tgtcacattt ttttattttt
      481 ttaccttcgc cgattgtaaa attaagctag acaactaaaa aagtcatttg tgctacactc
      541 aaaatagttc cgtcgaaaga attataagga gtgagtacaa atgacctata cccatcttac
      601 accaactgaa ctcgtaatga tagaagctta tttcaatcaa tcacactctg tttcaaaagt
      661 agcccatctg gtacaacgtt ctcgacaaac catttataat gtctatcgtt ttcttaaatc
      721 tggtggaagc gcaataagct actatgaaca atataagaaa aacaaacgta actgcggaag
      781 acgtccgatt gtgttaccag atgggcaaca agaatacatt caaaaaaagg tggctcaagg
      841 gtggactcca gatgtcctta ttggtcgagc agagtttcct attgcttgtt cggtacgtac
      901 actatatcgg atgtttaaag ataaaacctt tgaccctcac gatttaccaa tgaaagggaa
      961 aagaaaacca aacggacata aagaaaaaag aggaaaacaa gcttttcgcc gttcgattca
     1021 ggatagaaca actgattata tacagttcaa tcatgagttt ggtcacctag aaggtgacac
     1081 cattgtcggt ggaaaacata aaagtgcggt gatcacgtta gttgagcgat tatctaaagt
     1141 gatcatcacc ttgaaacccg ctggtaggca agctatagat attgagaata gactgaatca
     1201 atggtttcaa tctgtaccga aacacttgtt taaatccatc acatttgatt gtggaaaaga
     1261 gttctcgaat tggaaaaaga ttagtaatac caatgatatt tcgatttatt tcgctgatcc
     1321 aggaacacct tctcaacgag gactaaatga acattcgaat ggcttattac gtaaagatgg
     1381 cttatataaa gctatggatt ttaataaggt atccgaaacc tttatccaat cggtggcatc
     1441 aaaacgaaat catattccta gaaaatcatt acactatcgc acaccattgg aagtattttt
     1501 gagttacgta ggtaaagatg atttgtctag cttaatttga caaacgaaac tttgtaaaaa
     1561 tattcgattg aatattctat ttggcacgac tcacttggca gtatatgtat gtcaatattt
     1621 ttcatctgtt tcataggtat ttcaaaatct aaactattaa aaacatataa ttccctgtaa
     1681 ttatttacat ctaactctac taaatttatc tttggaacaa tagatcctcc acccattcca
     1741 ccataataaa aaaaatcttg ttctctatca aaatagcaca tattaagctc agtttgttta
     1801 tcatcctcaa taattttata aatcaaacct atataatcat gaatgctggc aaaaattttt
     1861 tttaagtcaa gttctaaatc ttcttcgaaa acacatttaa tttctcctac tgataattga
     1921 tactctatat tacatgactt aattagtttt ttagatcccc cctccagata ggcatatgtt
     1981 tcaataatta tgttcttttt attgcttggc aaatttccgt tatttattgc ataaattaaa
     2041 aatgactgtc tatttagccc ataatctaat acaacttctt catactcata tttctttaaa
     2101 tatttaatat gaaaatatgc tgaattaatc aaaactcgag tgttactgtt gttatttatt
     2161 gttgttctat tgtgtataaa attgtatagg ttgtcatatt ttcttggttt agtgaactac
     2221 tcaccactta gctaaaccta acggtttctt acgtttgaag tgggagcttc ttgggaagag
     2281 agcatacttg atagcgtatt actttactaa cagaggtgcc tcttatttac caagctatcc
     2341 ccgtagttcc tacggttctt gtttatttga tctaagccaa tcccatagag tgtagcctta
     2401 gaccttcggt caggatattg atactagcgt tgatatctcg gtcatgatga gtatgacaaa
     2461 tagggcaagt ccattttcga atttcgagag atttcttgcc gtctttatgt ccacaattcg
     2521 aacagatttg gctagatgga aaccacttat ctactttgat gattttccga ccgtaccagt
     2581 cagccttgta ttgtaattta gacacaaaac tagaccaaga aacatccgaa atactttttg
     2641 ctagtttatg attacgcaac atgccttttg tgtttaagtc ttcaatacag atgatatcgt
     2701 gatttttgat aatttctgta ctcaacttat tcagaaaatc agtacgttga ttcattactt
     2761 tttcatgcaa tcgtgctact ttacgttttt gtgtttgata atttctagct tcaaacagat
     2821 tgataccttt ttgtttagct aataaggcac gtcttgacaa cttacgttgt tcacgtttga
     2881 gtttcttttc cattttggac gtaaatttat tattatcaaa tttttgaccg gtagaaagaa
     2941 ttgcaaagtc tataatacct aggtcaatac caacagcaga attagattta ggtagttcgc
     3001 gaacttcttc tttgcataac aaagaaatat a
//
LOCUS       DACCVZ010000167         3009 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.171, whole genome shotgun sequence.
ACCESSION   DACCVZ010000167 DACCVZ010000000
VERSION     DACCVZ010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.171"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..482
                     /locus_tag="IVW63_002875"
     CDS             <1..482
                     /locus_tag="IVW63_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP7861091.1"
                     /translation="LTYRTEDEDSIRYFVLFTGFEINKTKKFVEVSVNPDLEYIINGL
                     TAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYYVVRIEEFRSLMDIPEYYQMGNI
                     DQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLEFTFSSLTSDLPKISLRNWLEE"
     gene            complement(619..1035)
                     /locus_tag="IVW63_002876"
     CDS             complement(619..1035)
                     /locus_tag="IVW63_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861092.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1038..1322)
                     /locus_tag="IVW63_002877"
     CDS             complement(1038..1322)
                     /locus_tag="IVW63_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861093.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            complement(2022..2117)
                     /locus_tag="IVW63_002878"
     CDS             complement(2022..2117)
                     /locus_tag="IVW63_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAP7861094.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            2770..>3009
                     /locus_tag="IVW63_002879"
     CDS             2770..>3009
                     /locus_tag="IVW63_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAP7861095.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLN"
BASE COUNT          958 a          478 c          565 g         1008 t
ORIGIN      
        1 atcttactta ccgtactgaa gatgaggatt ctattcgcta ctttgttttg tttactggtt
       61 ttgaaatcaa taaaacaaaa aagtttgttg aagtcagtgt taatccggac ctagaatata
      121 ttattaatgg tttaacagct gaatttagta gatttgaatt atctgctttc acgtcgttgc
      181 gttctacgta tgcaaaaact ctattccgac tgcttatgca gtaccgttct actggttatt
      241 atgtagttcg tattgaagag tttaggagct taatggatat cccagaatac tatcaaatgg
      301 gtaacattga tcaaaaagta ttaaatcctg cattacgaga actaaaaaaa tacttcaatg
      361 atcttaaagt cacaaaaata aaagcaaaaa agggcaataa aatcgccaaa ttagaattta
      421 ctttttcaag cctaacgtca gatttgccaa agatttctct gcgtaactgg ttagaagaat
      481 aaataaaaaa gaactcgccc cccttacatt aagcaagtag acaagtccct tacaaccgac
      541 taagattgct agtacattct agcatattgt atggggcttc taaataaaaa acagatagga
      601 ataactccta tctgtttttt atcgttttag aaaatttgtt gggtcgaaat ttctagaagt
      661 gactgtttga ctggtttctt tttgatgatt ctttggtcga tttcgatttg atggatttag
      721 tttagcttcg attttttctt tcacttcttg atatacttta gaatttgtgc caataagaac
      781 gcctgtatct tttagatata aatcagcaaa ttctgcgatg atttcagtca tgatggaaat
      841 ttcttttccc atagcattta gttttgcctg attgctggta gtggtcgtgt tggtatcggg
      901 ttcataactc atacataaaa agcgaatggc ttccgagtag ttattgatat ctggattttt
      961 ttcgatgatg gaatctaaaa cgtcaacatg actagggtac aaagtaacat gtttttggac
     1021 agaagttttt ctcatggtta tatcattcct ccgataagca tttcaatgat ttgattattt
     1081 gtgtagacat actcgcttaa tatttgagta ttttctgttt ggatagcaat aaatttatcg
     1141 agcaataaat cgaattggtc ttttttgtaa gtcgtaagtt gacggtcaaa atcactttcg
     1201 attaaaactt ttagatattt atttcgactc catttttctc ctgttttatt cgtgagttct
     1261 tggcaacgtt tgtctattgt tgcaacaaac tttggatcaa tattccgaac taaaatgtcc
     1321 ataaaaaatc tccttttgca attatgtata atttatgtat accatacaaa tactatattt
     1381 gtatagctgt tttttgccaa aatgctatac ataagctacc cacgatggcg aaaaagtgat
     1441 atcaaatttt tttctgagaa acgtgatagg cacagcctat ctacccactt tttttagaaa
     1501 gtgggtacac gtttccttat gctctttaaa attcgggggg gagtgctgca cgtgtaatcg
     1561 ataaccaaat ttaacagacg aaaaattgtt ggaatataaa aatatgacac ccgaaagaaa
     1621 acgatcgttg gaaaaattaa tgcaactagt gaacgaagac ggcggaattt cagacgcagc
     1681 ttttgacgca tggagcgaat ttcatggaga atataattaa gtgggtttaa atggctctaa
     1741 aatcgcttct aagagttttt tagcttggac caatgaaata caccaaaaac taaataaaac
     1801 gtcttaaatc gaaaaatacg agctctcaga gcgactttat ttgtaaatgt tgcatataag
     1861 aaataattac ggattttaga cttttgtagg atatttttga aataaatatt tatttctgtt
     1921 ataatttgat tgcaaataag tgaacacgaa acacacgaaa tccccagaga ggtcggattc
     1981 tctggggctt tttttgtggg ctgagtcgcc ttaattaagt tttacttctt gtttcggtta
     2041 ttcaaccagt aactgaacaa agcgcttaaa agcccaacaa gaagggagca aataaagtta
     2101 gtgaacacga aacacacctc cttccagtcg caagactgtc ggataggcga caatcaatta
     2161 tacaataaaa aagcaaaaat aagcctaagt tttttattgc cttggggttg ttagggcttg
     2221 ccctgaccgc ctgtaaggcg ctttagaacg aaggacatag tttttatcga atcttgtctt
     2281 agaacggctt agacgagctc tcaggacgcc acaaaggagt ccctaatgaa ttatttttgg
     2341 cgaaggagcc taaaggcgac tgctgcaagt aaaatgtgag agcgtagcga tcactccttc
     2401 ttacagcgac catagggagc tagattggca gtttaatatc atgcgcgaac ctgtttattt
     2461 taaaaagtgg gtgatttttt ggcgggaaat tttgctcgcg cgcgcgcgtt tattttattt
     2521 attttttaaa gattttttag aacccttttt agggggcagt tgagccttac tctcccaacg
     2581 gatacagaag ggtactaaca actttttatc tgagtactaa caacttttta tctgagtact
     2641 aacaactttt tatctgagta ctaacaactt tttatctgag tactaatatc cttttgtata
     2701 ataacaacca acctatttac gagttggttg ttaaaggtta ttatttattt gtaagggggg
     2761 aagaaaggaa tggatgaaaa aacggaatta acagtcaaat atcaaaatga attgaattta
     2821 gtaccgctga aaaatttcaa tgctaagcag atggatttat tttttgcatt atgcgctcgt
     2881 atgaaagatc gtggtttgaa aaaagttaga ttttctttcg aggaattaaa agagttaagt
     2941 gattataaga tgactgctac aaaagccttt gtcggtgatt tagaaaagct ctataaagat
     3001 atgcttaat
//
LOCUS       DACCVZ010000168         2796 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.172, whole genome shotgun sequence.
ACCESSION   DACCVZ010000168 DACCVZ010000000
VERSION     DACCVZ010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.172"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..433)
                     /locus_tag="IVW63_002880"
     CDS             complement(<1..433)
                     /locus_tag="IVW63_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861096.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNM"
     gene            complement(992..1309)
                     /locus_tag="IVW63_002881"
     CDS             complement(992..1309)
                     /locus_tag="IVW63_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP7861097.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            complement(1310..1564)
                     /locus_tag="IVW63_002882"
     CDS             complement(1310..1564)
                     /locus_tag="IVW63_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP7861098.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            complement(1824..2042)
                     /locus_tag="IVW63_002883"
                     /pseudo
     CDS             complement(1824..2042)
                     /locus_tag="IVW63_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
BASE COUNT          918 a          502 c          402 g          974 t
ORIGIN      
        1 tcatatttcc ttgattacct gaggcaatga aagacttatc tacttgaatt agggtgaaat
       61 tctcattcaa atatggtagt aaaattaata tatgtgaaaa tcgaatcttg agatagctat
      121 tccccttgag atattcactg atacttctac tcaaatcatt taaattttta taattatttg
      181 tacggaacgt atatatatca acatcagttt tctttacatg agaacttatt ctaaaatgaa
      241 aaagcctact ctcagaaaga attgaaaaat agatactttc agtagatact gaagattgaa
      301 caaaattaaa cttgtatcct tcaggcatag cacttttaac agtctgctgc attaactcgg
      361 ataatctttt gaaagtagta atatattttt taccagcaaa ccatacatat cttttttcat
      421 taagtatgtt cactatctct cctccattaa ttatatttag catcaaatag ttattgtacc
      481 tatattttat cccattcctt ttaaaacaag aatacgtaca aagtaaaatg ttgtaaatag
      541 tctagcaggg atgtatattt tcatgtacca acataatatt taagaagttt cccatagata
      601 tattggactt cctcttttaa aacacaaaaa taaatactac cttatttagg tagtatttat
      661 taaaagttac gtcaattttg attaaaaata tactacttga acctctcatg agtaaagtca
      721 cgaaattttt gggaatagag cgtacttgat atcttatttt ttcactaata gcagtgtctc
      781 ttattcacca agcgatcccc gtagttccta cggttcttaa tttttctcta gactaatgat
      841 tgtatcttta gaccttcggc cataacatgg agcaaaataa aaaggtacta agtcttatat
      901 atcaatcttc gagtaaccga cggttaacaa ccatatcgag cggcattaat cacccacctg
      961 tagaggatga gcgacttttg cctaattatt gttaaaagcc tagtttcatt tgtttagatt
     1021 ggaaaatacg tcctacaagt atctcttttt tttcatggtc gatccgataa aataaggcat
     1081 agcttttgcc gatcacgatc cgatatgttg ggatatccat tccatagatt tcggaaactt
     1141 cctcatgcat agttggaaaa tttttggtta gttctaaagc cttctggatc gcacctacaa
     1201 atctttttat gctggctgga gaaagagcaa gctcattttc ccattcttct attatcgttt
     1261 caaggctggt ctggaaactt ttagaataaa ctagcgtgta ctctttcatc tattcactcc
     1321 agccgtattt tccgaaagct tttaccattt caatttctga aactgttaaa cctttctcaa
     1381 agtcttggaa actttcttca atcaatttgc gatcgtgttc ttttgctatt tgagtagtat
     1441 ctaatatgaa taagttgcct tcttgtttgg cttggatagt gtctccgctt tttaatccaa
     1501 gagagcttgg aaggatcact cccacgctat tgccgatctt tctaaccttt agttcttttc
     1561 ccatgttatc acacttcttt tagtttttga taaataaatt ataacatgtt ataacgacaa
     1621 ttgccaacgg tgtttcttaa gggattccac tccatattat tattggacaa aataagccac
     1681 ttagaacgct gaaaacatat acaaacgata tcaaaatacg agtgaactac tcaccataca
     1741 cttccgttaa catccattta agtaggtatt tttattatat atagatttaa catatgtcgg
     1801 tcggttgatt gatatagcta aagttataac tcaaccgaag ccgattcatc tacacgaata
     1861 aagttgcgag tgttctcggc taattcataa aaattgttat gtgttccata tagcaatact
     1921 ggaataactt tattttcttg aatctcataa gcaactctat acacggtgac cgcatactta
     1981 aatccattag accaattacc tgataaacct ccagtttttt gctcttactt aaatggatca
     2041 atagcaattt catcacaaac ctatagagga tgagtgactt ctgcctaatt acgttaaaaa
     2101 atattgaaag taactctatg tagcaaaaaa tatctagaat ttcatttcct caaaactgat
     2161 cgatattgta tctaaaaata tatactacct aaaataggta gtatatatta aaatatgtgc
     2221 ttttgttaga aaaatcaata cataaattat catatctgta tatgtcattt aggtatttca
     2281 gttatgttat aatagttttg ctgtctgcta ccccggccta atctggcaag gggaggagga
     2341 gatataatga aatacctttt tgattttgtt tttgcaatca agccatttgc agaggtaact
     2401 gcacactaca tctgcaagtg gcttgattgc aaaattgcca aaaaagacag taagcctacc
     2461 agttaattct ataatataga aacgtaaaaa aaaccccatc agcctacacg ctgatggggt
     2521 ttgatgatat aatgaaatac ctctttgtta ctcataatta taccataatt agtcacgaat
     2581 gcaaccaata gaaaaaacta cttagaacgg tagatcatcg ctaataacaa tgcattgtcc
     2641 accaaatgga ttttgtgaag cattaaatac attgttatta attgtcgctg tttttaacta
     2701 ggcctctccc cttctattat aaaagaagat atatattatt tcttaattac ctactacctt
     2761 aaaccaaaat ttaagtacta cctaatttaa gtagta
//
LOCUS       DACCVZ010000169         2656 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.173, whole genome shotgun sequence.
ACCESSION   DACCVZ010000169 DACCVZ010000000
VERSION     DACCVZ010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.173"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            23..229
                     /locus_tag="IVW63_002884"
     CDS             23..229
                     /locus_tag="IVW63_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861099.1"
                     /translation="MSSKKNWVYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISI
                     IGIIIAAIITQLFLVFGEKKRSKK"
     gene            complement(320..685)
                     /locus_tag="IVW63_002885"
     CDS             complement(320..685)
                     /locus_tag="IVW63_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861100.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            893..1375
                     /locus_tag="IVW63_002886"
     CDS             893..1375
                     /locus_tag="IVW63_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861101.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1572..2462
                     /gene="pstS"
                     /locus_tag="IVW63_002887"
     CDS             1572..2462
                     /gene="pstS"
                     /locus_tag="IVW63_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HAP7861102.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT          917 a          424 c          516 g          799 t
ORIGIN      
        1 aggttttaga actaaacgaa gtttgtcttc taaaaaaaat tgggtatact cacaaactat
       61 tttttatgga ggaattgttt taattagttt actttcttca acactttatt ctttgaatat
      121 tatagatgtt tccacctcaa attcaatatc tattattgga atcattattg ctgcaattat
      181 tacacaactg tttttagtgt ttggagagaa gaaaagaagt aaaaaataga aaaactagtg
      241 atagttttgg tgatataaga aaaacatata tgtataaaaa gaagaaagta gcttctcttt
      301 gtacatatat ggtttgtttt tatggatgcc gagctttttt ataagataag gctaccgccc
      361 ataacgaccc aaggatttgt ggaactaagt aaatacctgc aagaagcaag atcagctggg
      421 tcggttttaa aggatgatag aagtaacgcc attcagtaaa attggcgcaa aataaatagg
      481 aagtgacagt agatataata ttggcaatga ataaagatat aatacgcctg ttcctttgaa
      541 aataatatcc agcaaaaaga gataaaaata tcaatgtgat gaacccgctt acggaatgat
      601 aacgaaaatc aagcagtaag gcgaaatgca cataaggaac aaaagataaa agcaacggaa
      661 ggtttttcca gcaagttttt atcatctttc atcaccacct aacaagtgtt attattttgt
      721 tagttttatt gtaaattgaa tcctgcaata atcaattact ttttcattat ttctagatta
      781 aatgaataaa ctctcatgcc attatctcta aaaaaaaagt ttttccccct aattttttta
      841 gatagaaaat tgtatagtat gatgagagaa aaagtagttt gggggaacgt taatgagaag
      901 aaaagcagta atcgatcggc tttatttatt tttttggttt tttcctatcg ttttgctacc
      961 ttttacatgg gtaaatgctg ttgtacaagg tgcggagata ttaggcctga tccaaggaag
     1021 cggatttgtg gtttctagga attttccagc tttgattgtt ttctatttag tgataagtgt
     1081 aggtctctta ttaccaaaat ctctgatcaa tcactacaat tggcagctgc tttacttttc
     1141 ttgcttatta gtatttacat ctatgttttc tttgctgcct cgcttgatta tcggccctaa
     1201 tggtttgagc gagagtggat tgaaggattt agcttattcc tccatgtatt tcttgacgat
     1261 caaaccatgg ttctatttag taattgcctc atttattctt gcaacatttt tttacttctg
     1321 gacagaaatc aggataaaaa gtgaacgatc tgtatctata aaaaataact attgatggtg
     1381 gatcatcagt aaaaaaacat atgagctgcg taaaatgcat gtttctcata tgcttttttt
     1441 attattatgt aaagaatgcg aaaaacgttt acatgatttt tacataactt aactatattt
     1501 ttacagcaac catacgaggg atttacagtc gactgataaa ctttagttgt aaataagaaa
     1561 ggagcaataa aatgaaaaaa gtattgttta ctctaggtat gatgggaatt cttttagccg
     1621 gatgcggctc aggatcagga aatacagatg gctctgccac acaaaataat tcaagtgact
     1681 caaatgaaca agtaaaaatc gttgcggtag gttcgacagc attacagccg ttagtcgatg
     1741 cagcacaaga aagctttgta caagaaaatc caaattatca aatctctgta caaggaggag
     1801 gaagcggaac tggtttgagc caagtcgaag ctggagcagt tactatcgga aactctgatg
     1861 tatttgcaga agaaagagac ggagttgatg cttcaaaatt agtggatcat aaagtagcag
     1921 tggtcgggat ggcaccaatc gtcaataaag atacagatgt caaagatatc accaaacagg
     1981 aattgattga tatctttaca ggaaaaatca ctaactggaa ggaagttggc gggaaagatc
     2041 aaaaaatcaa cgtcgtgaac cgtgcaaacg gcagcggtac ccgcgcgaca ttcgaaaaat
     2101 ggggactgga tggtgctacc cctgtgcagt cccaagaaca agattcatca ggaacagttc
     2161 ggcagctggt aagtcaaaca ccaggagcaa tcagctattt agctttctca tatctcgatg
     2221 attccacaca agcactaagt atcgacggtg tagaaccaaa agaagagaat gtagcagata
     2281 acagctgggg aatctggtca tatgaacata tgtacacgaa cggaaaacct tcccctgaag
     2341 tccaaaaatt cttagactac atgatgacag aagaaatcca agaaggacct gtcaaagaat
     2401 tgggctattt accaatcaca atgatggaag tagaacgtga tcacgaagga aatatcaaat
     2461 aactagcaga taaacatgcc acggtagtcg ttactattaa ggaaaaatca actatgtttc
     2521 cccacatata catttttcct ttaattgtga aaaatagttc ctcatatttt gccgtttttt
     2581 gagctaatac cgagggtcag ctgattgaac accgtttatt cgaaaaaaag agctacgaca
     2641 tagaactgtc gtaact
//
LOCUS       DACCVZ010000170         2471 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.174, whole genome shotgun sequence.
ACCESSION   DACCVZ010000170 DACCVZ010000000
VERSION     DACCVZ010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.174"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(217..765)
                     /gene="aac(6')"
                     /locus_tag="IVW63_002888"
     CDS             complement(217..765)
                     /gene="aac(6')"
                     /locus_tag="IVW63_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAP7861103.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            1317..2420
                     /locus_tag="IVW63_002889"
     CDS             1317..2420
                     /locus_tag="IVW63_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP7861104.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
BASE COUNT          776 a          483 c          431 g          781 t
ORIGIN      
        1 attaagccaa atttatgcaa aaatgtagaa agccattttc acaaaatttt tcttactact
       61 cgaaactaag cgactttttc acaacctctg gtacacggtg ttccaaaagt agcttcttcg
      121 gaaataagtt ggaatttcac aaaaattcaa gaagtaattt tcgtaaattc cttcttattt
      181 cttgaagctg attacttctg tcacaacctc tttttattat tgagaatttg gtcgaggaat
      241 aatcgttttt gccatccaaa tatccggttt gtcccagcca tttgcatttg gtaagacacc
      301 tacgatttta taacctaatt tttcatagaa ttcatacgga tgttcacgaa ggttctggat
      361 ggaagccact ttatcaaatg tatgctcata caggtccgtt tgacttaacg ttgttccatg
      421 gtctaaatca tccgtaccta aataaatcgt gattcctcct ctggaagcta cttctttttc
      481 taagtaattg actaatcgag tacctatttg gttctttcgt cgggagcttt ctacaactaa
      541 tggatgcaat tcccaacctg tgataccgta ttgagggatt gcaccaataa atcctactaa
      601 ctcatcttgg tctaccgctg ctaccgcgat tcgttctgga ttcatcattt cttctacttc
      661 ttctgccgag ctgtctccat attcttccgg ccaagtcagt ctcagtaaat cagaaagctg
      721 atctttcaat actggattat tacggtcaaa ttcactgatt atcatacgtc ttcccccttg
      781 ttcttgctta ttctaacagt ccttttgaaa aaacgaaatg ttctcgctca aaaatcttta
      841 gctaccaatc agtatctcta ttctttcatt atttatctta cttataaaat aaaaaattat
      901 acagaaacac tttattcaaa ataggaaaga tcaggaaagc catcaattgg aggaaaaaac
      961 tctgtttgtt catcatgata tagattatct tttgctttaa aaaaaaccaa ttatgaattg
     1021 acaaataaaa cctgttttca tataataatc ttaattttta gaatttttag ataattacaa
     1081 aaaagcaaag ggaatcggta gaaatactaa gaggaacaaa aattcattat tgtcgttttc
     1141 aatgtttttg tacttgttcg tttttaggat acttattgat gatttcaagg tgttcatgcc
     1201 accttattca tcacttatcc tgtcttaggt tcacctctac tccatctaca gccgcagtca
     1261 gatcgatcac tctttaaaat tttaacccgt ttcaacgaag aaagaaggaa atgaatatga
     1321 gtcaaagtgt tttcttacca aattatacca ttggaacaga tgcgtatgaa aaagcaaatg
     1381 gaatcgtcaa agaatatggg acaaaagtag tgctgattgg agggaagact gcactttcaa
     1441 aggcagaaaa caaaataaaa gtagctttga cacaggaaat agaggttgtc gccagtctct
     1501 ggtacggggg taattcaact tatggaaata ttgaacagtt gatccagcat gaaagtgtcc
     1561 aaaaagcaga cgtcctgttt gcagtcggtg gtggccgtgc ttgcgatact gtaaaagtca
     1621 ttggtgaaaa actagctaaa ccagtcttca cctttcccac tattggttcg aactgttcgc
     1681 ccgtcactgc ggtatgtgtc atctataacg aagaaggcgt aatggacgga ctcttctttc
     1741 cttcaaaacc acctgtacac accttcattg atacagcaat tattgccgaa gcacctgata
     1801 aatacttatg ggcaggtatt ggcgatgctt tatccaaaga agtcgaatct actttttctg
     1861 ctcgtggcga tgatctaggc tacacggata gattaggaat ccaaatcgga aaaatgtgca
     1921 ttgatcgtct cttgacttat ggtacgcaag cattgaaaga tagtgccgac gatcgtccct
     1981 catatgcaat tgaacaagtc gtttcggata tcattgttac taccggattg gtttctgttt
     2041 tagttaacaa taactataat tctgctatgg cacactcatt ctattacggt acgactgttc
     2101 tagaaaaaat ggagggatac cttcacggag catctgtcag ttatggtgta ctgaccttat
     2161 tgatgatgga tcagcagttc gatttgtttg ataaaatcta tgtgtttatg aaaaagaacc
     2221 aacttccagt atcgttaacc gacatgaatc tcaatgtcac gaccgattta gaagcaatct
     2281 tagataaagc catggcaaca aatgatatta aacatgtgcc ttatgaaatc acccgagaaa
     2341 aatttaaaca ggccattctt gacgtagaaa cttatcatgc tacacaagaa agccagcaag
     2401 gatataagaa aatcagttaa ataattgcta aaacccccat caagcaggct gtcatcaaat
     2461 tgaggacatt t
//
LOCUS       DACCVZ010000171         2451 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.175, whole genome shotgun sequence.
ACCESSION   DACCVZ010000171 DACCVZ010000000
VERSION     DACCVZ010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.175"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            293..>2451
                     /gene="acm"
                     /locus_tag="IVW63_002890"
     CDS             293..>2451
                     /gene="acm"
                     /locus_tag="IVW63_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HAP7861105.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYK"
BASE COUNT          973 a          359 c          469 g          650 t
ORIGIN      
        1 tatcgttatt tattaatgtt gcatttttgt aagttaaaaa ttggaaatat agattgaaaa
       61 aatgaaagca ataagtaaaa taaaatgaat atatgcgaaa aaataattta cattaggaaa
      121 aaccttgtaa aaacagtttt ttggcatatt tattttttat aaatatttgt aaaataacta
      181 tcaatttttt agttaaaaga ttggaaatga gtgggggagg aattgaagaa aggatttttg
      241 agagatgata tagtaggttt tatttttagt taaaataggg gagatagaaa aaatgaaaaa
      301 gtgtagaaat attattttat caatgttatt tattattact aatataacat cactgattcc
      361 tgttcatgtc tatgcggatg caggcagaga tatcagcagt aatgtcactt cgttgaccgt
      421 ggacccaacg aatattacag atggaggaaa cataaaagta aaattctcgt ttgacgaaaa
      481 aaaacaaaat atccaaccag gtgattatct ttggatcaat tggccaagtg aaggaaatat
      541 tcgcggtgaa ggattccaaa aagaaatccc attaatgatt gaaaataaaa atgttggaac
      601 tttaacggtc agaaaagatt ctgcgcaggt tgtgtttaat gaaaatatta aaaacctaga
      661 ctcagtagaa ggttgggggc aatttgagat acaggccaga aacgtaaccg ataccggtga
      721 agaaaatacg ggaccattca ccgtgacgag cggtgataaa acagctactg taaatgtgac
      781 aaagccagct tctggttctt cttctagcgt tttttattat aaaacaggag acatgctacc
      841 tgaagatact aagcacattc gatggttttt gaatattaac aataacggca cttatgttga
      901 acaaccagtt aaaatcagtg atgaaatcca aagtggacaa agattagatc caagtacgtt
      961 tgaaattaat caaatacact taggtgaaca gaaggtttat agaggagaag agggaatcca
     1021 acaattttta caagatttcc ccagcgctac atttaatttt tcagtaactg ataattacat
     1081 tgaaataact ataccaaaaa actttgtcaa tcttaggaaa ataatggtga gttataagac
     1141 gatcatagaa aacccagaac aaataaattt tgagaatcat tcggaagctt ggtttaaaga
     1201 atttaataaa cctgctgttg atggagaaag tttcaatcat acagttaaaa atatttcagc
     1261 ttctggtgga gtcaacggta cagttagagg cgaattgaag attttcaaat atatcaatga
     1321 cacagagatt ggtatcccaa atgtgacttt cgaattaaga cgagcagatg aacagcctat
     1381 tcaaggacag tctagtatcc tgttgacttc gaatgaacag ggagaagcta gtatcaaagg
     1441 cctgcaagta ggagactatg ttgtaaaaga aaaagaagca cccaattgga ttgattttga
     1501 tccactaagt tcaaatgaac tcaaattctc cataaacgaa aatgatacag agggagtcag
     1561 tttacctatt tataacaaga aaaaggttac gaacatcaca gcaactaaaa tttggaacgg
     1621 tggaaccact ccaagaccga gtatttattt taaattattc agagcaagta caaacaattg
     1681 ggaaccagtt cctgatgcag aaacaaaacg attagacaat ggaataactt cagtgacttg
     1741 ggaagatatc caacagtatg atgatagtgg aaacgaatat acgtttaaag tgcaagaagt
     1801 agatcaaaac ggaaatgatt atgtcccttc aggttatcaa aaaattgaaa acgggctagt
     1861 cgttacaaat gagaataaag aagtcatttc agtctcagga caaaaaacat gggaagacaa
     1921 tgagaaccaa gacggcaaac gaccgacgac gatcacagta aatctattag ccgacggtca
     1981 accgatccaa cacaaagaag taagtgaaaa agatgattgg cgctatcgtt tcacaaatct
     2041 gccaaaatac agagacgggc aagaaatcat ctatactgta acggaagaca acgtgcccga
     2101 atacagtacg acgattgacg ggtataacat caaaaacagt tatacaccgg aaaaaacaaa
     2161 tatatctata ccaggtagcc atataacacc gtggaaaaat tttccagaga agacagagag
     2221 agagaaaatt agaaatctat tctctcaaaa attgcaaata tttgctcata caggagaatc
     2281 cagcgaacaa agaagcaatt atattagtaa gagagctgta cctaaacaga taacaaataa
     2341 atcaaaaagc attcttccta aaacaagtag taaaaaatct agttttgctg taatcattgg
     2401 tttattgata gtaactatct gtgctgggat attcttacaa aaatataaaa a
//
LOCUS       DACCVZ010000172         2438 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.176, whole genome shotgun sequence.
ACCESSION   DACCVZ010000172 DACCVZ010000000
VERSION     DACCVZ010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.176"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            387..1325
                     /locus_tag="IVW63_002891"
     CDS             387..1325
                     /locus_tag="IVW63_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAP7861106.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            1338..2390
                     /locus_tag="IVW63_002892"
     CDS             1338..2390
                     /locus_tag="IVW63_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP7861107.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
BASE COUNT          736 a          377 c          527 g          798 t
ORIGIN      
        1 tttttaaata agtgtattgt tcgattttaa taaataataa gcaataccat ccgtctgtgt
       61 tgcgcaacat cgtactacaa tgaatatttt ttcacaaaaa gaaaatcatc catcgaatga
      121 atggaaggtt ttagtataca cgaggttaat gccccctctt ttataatcag aggagtgagg
      181 ttttttctat gaatgtttct attttcttat tgctagtcta gtttctctta cgatgaaatt
      241 gggattctat tccagttttt attgatttgc tgataaaata acttgaatgg tggatataaa
      301 catgataaat aagagaagaa taacaaaaca aggttgtgaa atgattctca aatgaatata
      361 atagaaagaa aaaggaggaa gaatcaatga aaatagcaat tgcaggcgct ggcgcaatgg
      421 gaagtcgctt tgggttaatg cttcaccaaa gtgggaacga agtattatta atcgatggct
      481 gggcagaaca tgtccaacaa atcaaagagc atggattaca agcaaatttt aatggtaaag
      541 aggtagaagc aaaactacca atcgttcttc aatccgaagt agaaaaagaa gatcaagttg
      601 atctgattat tctatttacc aaagcgatgc agctggaaaa aatgctgcag gatatccaat
      661 cattaatcaa aaaagataca gaggtcttat gtctattaaa tggtatcggg catgaagata
      721 ttattgagaa atttgtacca atggaaaata tctatattgg aaataccatg tggacggcag
      781 gtcttgaagg tcctggtcag gtcaaattat ttggaagtgg ttcagtagaa ttacaaaatt
      841 taggtgatgg aaaagaagca gctgcaaaaa aattagcaga caaattgtct gaatcaggat
      901 taaatgctca tttttctgac aatattcact attctattta tcgcaaagca tgtgtgaacg
      961 gaacaatgaa cggactatgc acaatcttag acgttaatat ggctgagcta ggaaaaacat
     1021 cgactgctca taaaatggtg gcgacgattg tcaatgagtt tgccaaagta gcagcagtag
     1081 agaagattga actagatgtc ccagaagtca ttgcacattg tgaatcttgt tttgacccgg
     1141 aaacaattgg gttacattat ccttcaatgt atcaagactt gattaagaac catcgattaa
     1201 cagaaatcga ttatatcaat ggcgcaattt ctagaaaagg gaagaaatat ggtgttgcga
     1261 cgccttattg tgatttcttg actgagcttg tccatgcaaa agaagatagt ttgaacgtaa
     1321 aataaaggag agattgaatg gaaacttcac aaaaaatatc accgaaaatt tttctgaata
     1381 aagtcctcgc tggtacagca acaggaatca ttattggatt gattcctaat gcagtattag
     1441 gtgccatttt aaaatatttt agtgcgtatc cctttgcggt aacgatcgca cagttagcag
     1501 ttatttttca actagcaaca cctttgatca ttggtggttt gattgcctta caatttggat
     1561 ttgatccgat gagaatgatg gttgtagccg gagcttcttt tgttggttct ggtgtagtca
     1621 aattcacacc tgatttgggt gaaacgggtg tttacgttgg tgctggtaca ggcgatatta
     1681 ttaatacgat gctgacagca tcgattgctg tcgggctgat tttactgatt ggaaatagtt
     1741 ttgggtcagt gtcgattgtg ttaacaccga ttgttgtagg tgtaggtgca ggtttacttg
     1801 gtttttattt attccctttt gtaacagcaa ttacttctgc aattggatca ttgattaata
     1861 acttcactac cttacaaccg ctgttaatgt ctatcttgat tggttgttcc tttgcctttt
     1921 tgattatctc tcctatttca acagtagcaa tcggaatggc aatccaacta gatggtgttt
     1981 ctgctggtgc ggctgcgatg ggcgtagctg caaccacttt tgttttagta gtgaactctt
     2041 ggaaggttaa taagtcaggt gtgacaattg cgattgcttt aggcgctatg aagatgatga
     2101 tgcctaatct atttagaaaa cctgtgattc ttattccttg tttagttagt gcagtgatta
     2161 cagctattcc tgtcgctcta ttttctattt caggtacgcc tgcttctgct ggtttcggcg
     2221 tggtcggact tgttggtccg ttggcttctt tagatgcagg gctaaatggc tttcttgttg
     2281 ttctttgttg gttagtcatc cctgtttttg cggcactaat tactcaattt ttatgcgaga
     2341 aagtatttaa actgtatgat cgagaagaag tcttcaaatt tttaggctag tagattttac
     2401 ggctcttcgt caaattgtgt tggcgaagac aaatttga
//
LOCUS       DACCVZ010000173         2398 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.177, whole genome shotgun sequence.
ACCESSION   DACCVZ010000173 DACCVZ010000000
VERSION     DACCVZ010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.177"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            207..2069
                     /locus_tag="IVW63_002893"
     CDS             207..2069
                     /locus_tag="IVW63_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7861108.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="IVW63_002894"
     CDS             2069..>2398
                     /locus_tag="IVW63_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7861109.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DACCVZ010000174         2386 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.178, whole genome shotgun sequence.
ACCESSION   DACCVZ010000174 DACCVZ010000000
VERSION     DACCVZ010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2386
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.178"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            83..2236
                     /locus_tag="IVW63_002895"
     CDS             83..2236
                     /locus_tag="IVW63_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAP7861110.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          813 a          423 c          530 g          620 t
ORIGIN      
        1 ttgctccgcc cattttttct tttttattaa gaagtttttg ggtacaatga agcatgaatg
       61 taaataggcg gaaggatagg aaatgatgaa agattttatg aaaaaaatat taaatacttc
      121 ttggttagaa aaaataagaa aaggtgcaca agaacctaag aacaaaacgt ttcgccggtc
      181 ccatgttcct tttcgcttaa attttctttt tttcattata tttacgttat ttgttgcgtt
      241 gattgctaga ttgggttatt tgcagatcgt gaacggcgaa gagatggagg cgcgagtgaa
      301 gtctacttct acgattacgg tccaagaaag tactcctcgc ggaatgatct acgactccac
      361 aggaaaagct ttagttacga ataaagcgaa tcaggccatc acatatacga gaggaacaca
      421 agttacggct aaagatttgc ttgaaatcgc aacgaagctg aactcgctga tcgatgttcc
      481 ggtagatgaa aatctgacag atagagataa aaaagatttt tggctggctg atcccaaaca
      541 tttgaaagaa gccacaaaaa gactttcggc aaaagaaaag caattaggga acagcgaaca
      601 atatagtgcg atggtcaata aagtcacagc tgatgagatt aatttaaacg aggagcaatt
      661 aaaaattgct accatcttta aacggatgaa tagtgcatat gaattaaaca ctgtctatat
      721 caaaaactct ggtgttactg atcaagagtt agctgttgtg gcagaacgcg cttctgaact
      781 tccaggagtt tcgactggca cagactggac acgagaatat aatgcagcaa gttcactgaa
      841 aagtattctt ggcagtgtga cgactgaaaa gcaaggactt ccagcagatg aagcagagaa
      901 atacctagca aaaggttatt ctcggaatga ccgtgtagga caaagttatt tggaaaaaca
      961 atatgaagat gtcctgcaag gaaccaaaac ccaatatgaa gtttcccttg ataatgaagg
     1021 aaatgtttcg aatcaaaaag aaatcttctc tggggaaaaa ggttctaatt taatgttatc
     1081 tatgaatgca gaattccaat caaaagtaga agaaattttg aaaaggaatt atcaaacatt
     1141 gatcaacaac ggcaaagcac agtattcgcc tggtgcttat gcagtggcta tgaatcctca
     1201 gacaggagaa gtgctagcaa tgactggttt cagtcatgaa caaggttcca aagaaatcac
     1261 cgagaatgct ttaggcacga ttactagcgc ctttgatcca gggtctgtag tcaaggctgg
     1321 tactttgaca gcaggctggg caagtaacgc gatcagcgga aatcaagttt tgattgatga
     1381 gccgattcgt ctgcaaggtg cttcagaaaa aagctctgtc tttaatcgaa gcggacaagt
     1441 tgctcttgat gcagtcaaag catcggaatt gtcttctaat acgtatatga tcaaagtggc
     1501 gttaaagatg ttaggactag actatacacc tggaatggga ctacctagtt tagatgaaga
     1561 agctaaagct tatcagcaat tgagagactc tttcaaagag tttggtcttg gtacaacgac
     1621 tgggatcgat ttgccgaatg aatctcctgg gatctcacgt tctgttgatt atatgaagaa
     1681 gttcaatgcg gataatggca aagaatggta tgctccaggt aactttaccg atttggcatt
     1741 tggacagttt gacacatata caccaatcca attagctcaa tatgcttcaa cagtcgctaa
     1801 tggcgggaaa cgagtacagc cgcacctagt caaagcgatc tatggcaatg acgaaaatgg
     1861 aaacttgggt gaagtgaaga aagaaattgg cacaacagta gaaaatacgg tcaatatttc
     1921 tgcagaaaat atggcgatcc tccgtgaagg attccaccaa gttgtccatg gtaccgatcc
     1981 ttacacaaca gccaaaccat tagccagtgc gaaaatggac ctttccgcaa aaacagggac
     2041 tgcagaaacg gttgcggaag gtcatccaga tattgcgaca gtcaatagta atatcgtggc
     2101 atacggacca acagacaatc cggaaattgc catcagtgtt gtcttgccga acttattaga
     2161 cgaacaagac cacataaact tgacgattgc taaagaaata atggacgcgt attatgatat
     2221 gttcatggca aaataaaaaa gaggtcgtga aaaagccgct tagtttcgag tatgaagaaa
     2281 aattttgtga aaatagcttc tcacattttt gcttaaattt gacttcatac cgagaaactg
     2341 gcttttgaac accgtttact cggcaaaaaa ggttgtgaca aaaatt
//
LOCUS       DACCVZ010000175         2258 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.179, whole genome shotgun sequence.
ACCESSION   DACCVZ010000175 DACCVZ010000000
VERSION     DACCVZ010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.179"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(493..1785)
                     /locus_tag="IVW63_002896"
     CDS             complement(493..1785)
                     /locus_tag="IVW63_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP7861111.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(2059..>2258)
                     /locus_tag="IVW63_002897"
     CDS             complement(2059..>2258)
                     /locus_tag="IVW63_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861112.1"
                     /translation="IFTDWLGVLFSNLIPILIIGICGIILSILELFESRNTMNRIFAC
                     IILIVNLLPMVYFTFLYFALG"
BASE COUNT          739 a          427 c          357 g          735 t
ORIGIN      
        1 ttatattata aattcacatg attatcgaat tttattaagt tagtttttct tgtaaatctc
       61 tgttcccaat gaaactcgag acacttattt taaagaggaa acaatgtggt atttaaatag
      121 ccctcttgta tgggctactc tgtgatactt attagccatt aaactatttt acccacatag
      181 catatatttt gaaatcgttc attccgtaaa ttcaactaaa tatgcctaaa aaaataaaaa
      241 atctaagata gaataagatt tattcagtct tagatggatt tatagcaact ttttcgtaac
      301 aactttaaaa aatacgaaaa gaaagagctg ttttactctg actacgttgc taaattgtcg
      361 tttaatcatt catttaaacc aaatcttttt ttatagaatt cgttttaatc ctcctgaatc
      421 caaaaactat gaaaaccgta attaaatagt taagagtttt taaccaccat aattctctcg
      481 gctattttga aatcagataa attttgatcg gacacatagt tgaataaacc taccgttgtt
      541 acggaaggta aatcgcatac ttttcattct agaggagaag gtctcgttga tcattaactg
      601 attaagcacc atagcccagt tttgaattcg accacctgac cacttcgcgt gtaattcttt
      661 cgtgcgtaaa taaagtagtt ttaggagtgc attctcatta gagaacgctc ctttttttgt
      721 gacttttctg aagctggagt ggacactttc aaccgcattg gtagtgtaca taatttttcg
      781 aatggcacta ccataatcaa atagttgttc aacatgtgca aagttccgtt tccagacatc
      841 tacagcacca gaataatgag accaccgatt ttgaaaactg tcaaaagcag catgtgcagc
      901 gtttagagaa gaagcaccgt agaacttttt catatctcgg cagacttcct tatagtcctt
      961 acttggaata tagcgcaatg catttcgaac aagatgaaca atacagcgct gaacaattac
     1021 cgatggaaag atcgcttttg cgccttcttc gaggccagaa acaccgtcca tcgaaatgaa
     1081 aaagacatct tcgacaccac gtgctttcag ttcatcaaat acttgcatcc agcgattttt
     1141 agattctgtt tgatttaacc ataatcctaa aatctcctta tttcctttga gatcatagcc
     1201 aagaatggtg tatacagcat attctttggc ttcataattt tctcgtaaag taacatacat
     1261 acaatcaacg aatagaaagg cataacactt tgctaggggg cgggcttgcc attcttccaa
     1321 ttcaggaagg acagcgtcag tgatatctga aatcatttca tgggaaatat caaagccata
     1381 aatagcttcg acggttgcgg caatatctcg ttgactcatt cctcgtgcat acatggaaag
     1441 aaccttccct tcgatgtcgg agacatctcg ttttctctta ggaattaact ctggttcaaa
     1501 ggaagcttcc cggtctctag gaacatcaat agctacttca ccaaaactgg ttttaagcgt
     1561 tttagttcca tagccatttc gacggttatc gtgttcctta ggctctttag aatgggcatc
     1621 ataacctaaa tgattattca attctccttg aagcattttt tcaaaaaggg gcccaaacac
     1681 atctttcaaa gcatcttgca tgtcatcgac agattcaggt tgataggcat tcagaatgga
     1741 ttcagctaac ttttcggcat caggatttct tttctttcta gccatcgtgt aatcacctct
     1801 tgatcttatt gtagaaaaag aaaaaccgcg aagcaaccac ctgcctagga ttaatggtta
     1861 cttacacggt ttatattaca ctctcatcat taaaaaagta tctttcgata ttactaaaca
     1921 atgaaattat ctatttgaaa tttaaatctg ataatatatt gagtgttcca atgagggctt
     1981 tgatcctatt atccatatct ttttcagttt taatattgat acacattata agaaaaagaa
     2041 acttttggtt aatttatttc atcccagtgc aaaatataaa aaagtaaaat agaccatagg
     2101 caatagatta acaattaata taatacaagc aaatattcta ttcattgtat ttctgctttc
     2161 aaaaagttct aatattgaaa gtataattcc acaaatgcct ataataagta tgggaataag
     2221 attagaaaat aacaccccga gccaatctgt gaaaatta
//
LOCUS       DACCVZ010000176         2199 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.180, whole genome shotgun sequence.
ACCESSION   DACCVZ010000176 DACCVZ010000000
VERSION     DACCVZ010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.180"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..233
                     /locus_tag="IVW63_002898"
     CDS             <1..233
                     /locus_tag="IVW63_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP7861113.1"
                     /translation="YTKTEHRTVKYMNNLIEQDHRPIKRRNKFYRSLRTASSTIKGME
                     TIRGIYKKNRRNGTLFGFSVSTEIKVLMGIPA"
     gene            316..933
                     /locus_tag="IVW63_002899"
     CDS             316..933
                     /locus_tag="IVW63_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861114.1"
                     /translation="MWIFKQEIFAKLFSLDGLGWGILFFIFLFLGSMWIWFVDKKNSY
                     EKVIVKKMNRNEFDDFSKEHRVELYDSHEINSTSPSYYWVFGCEEKPLEIKLLKMLEN
                     PPVIEDFSAKNVEKQMFEQVQIRGQNKISLEPDEYAAFFLETNSGTSMPVFKVKLKMN
                     GRLCTYDLVANMRYGSTGDRRTILKFEQTFRSFLKNRVSQIFNLD"
     gene            1097..1429
                     /locus_tag="IVW63_002900"
     CDS             1097..1429
                     /locus_tag="IVW63_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861115.1"
                     /translation="MNNREILAKEMADLKAKEAKIRAKRKQIRQKEMISLAKLYCKKE
                     GFKTPAEALDFLESNKRNHSVNDEVLVSLRKFADGLVWQENGAYWRTNDVKGLTQFMA
                     QFRSENVN"
     gene            1753..1914
                     /locus_tag="IVW63_002901"
     CDS             1753..1914
                     /locus_tag="IVW63_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861116.1"
                     /translation="MAYMVARTQKHKVGSLNGLQNHVDRKTKNHTNKDIDITKSGSVA
                     KFSKKSILV"
     gene            1946..2199
                     /locus_tag="IVW63_002902"
                     /pseudo
     CDS             1946..2199
                     /locus_tag="IVW63_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
BASE COUNT          790 a          285 c          441 g          683 t
ORIGIN      
        1 tatatactaa gacagagcac cgaactgtga agtatatgaa caatttaata gaacaagacc
       61 atcgacctat taagcgacgg aataaatttt atcgaagtct ccggactgcc tcatccacga
      121 ttaaggggat ggagaccatt cgaggaatat ataaaaagaa ccgaagaaat ggaacgctct
      181 tcggcttttc ggtgtctact gagatcaagg tattaatggg aataccagcc taagatattt
      241 ggagttcaga gagggcgcgt ttgattttca aacttcgcaa cagaaccatt attttaaagt
      301 gggaggaaaa ttgttttgtg gatatttaaa caagaaatct ttgctaaatt atttagttta
      361 gatggattag gttggggaat cttatttttt atttttttat ttttaggatc tatgtggatc
      421 tggtttgttg ataaaaaaaa ttcttatgag aaagtaatag tgaaaaaaat gaatcgaaat
      481 gaattcgatg atttttcaaa ggaacataga gttgaattgt acgatagtca tgaaattaac
      541 agtacttctc catcttatta ttgggtattt ggttgcgaag aaaaaccatt ggagattaaa
      601 ttgttgaaaa tgcttgaaaa tcctccagtc attgaagatt tttctgcaaa aaacgttgaa
      661 aaacagatgt ttgaacaggt acaaataaga ggtcaaaaca aaatttcatt agaaccagat
      721 gaatatgcag cctttttttt agaaacaaat tcaggtactt caatgcctgt tttcaaagtt
      781 aaattaaaaa tgaatggtcg tttatgcact tatgatcttg ttgcaaatat gcgctatggt
      841 tctactggtg atagacgtac tattttaaaa tttgagcaaa cctttagaag ttttttgaaa
      901 aatagagtat cccaaatttt taatttggat tgaaaaaatt aaaaatttgg ccaaaaatac
      961 tacagttttt tagagcaatc atcttatgat gattgctctt tttttgttgt ttttgtgtca
     1021 ttcgttgttc aaatcctcta ttcgtaaaat aaatatttta aactagaaat atgccttatt
     1081 tttaggagga atcaaaatga acaatagaga aatattggca aaagaaatgg cggatttgaa
     1141 agcaaaagaa gcgaagatta gagcgaaacg aaaacagatt agacagaaag aaatgatttc
     1201 tttagcgaaa ttatattgta aaaaggaagg ctttaagaca cctgctgaag cattagattt
     1261 tttggaatca aataaaagaa atcattcagt aaatgatgag gttttagtat cgctaagaaa
     1321 atttgcagat ggattagttt ggcaagaaaa tggtgcatat tggcgtacga atgatgttaa
     1381 gggtttgact caatttatgg cacaatttcg ttcagaaaat gtgaactaaa ttgaggaggg
     1441 gttgaagtga aaagcaatac ttttcacttt tggttttttg cggaataaaa attgtgaaaa
     1501 caatgacgca aaaagccaat ggttttgaac gaaaaaagga cgtaaaaaag gaatgcgaag
     1561 gcagtcgttt ttcgttcgct ttttcgtttg agagaaacgg agtttctcat cggctgttaa
     1621 gccgatatag ccctcggcag agcttacaga ctttacgcag tataagtcta gtaagttata
     1681 ccttacatgg aggtttttcc gaatttagct tgtgattctc gcaataattt taacgaaagg
     1741 aagtacacag ttatggccta tatggtggca cgaacacaaa agcataaagt tgggtcgtta
     1801 aatggacttc aaaatcatgt agatcgtaaa acgaaaaatc atacgaataa agacattgat
     1861 attacgaaaa gtggttctgt tgcaaagttt tccaaaaaat ctattttagt gtaaaattga
     1921 gaaaaaagac agagaggata gagtaatgaa tcattttaaa ggcaaacaat tcaaaaaatg
     1981 acgtcattat tgtcgctgtt agttactacc tgcgttacaa tctaagctat cgtgaagttc
     2041 aggaattgtt atatgatcgt ggaataaatg tttgtcatac tacgatttat cgttgggtgc
     2101 aagagtacag caaagtcctc gattatcttt ggaagaagaa aaatagacaa tccttctatt
     2161 catggaaaat ggacgaaacc tatatcaaaa ttaagggac
//
LOCUS       DACCVZ010000177         2170 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.181, whole genome shotgun sequence.
ACCESSION   DACCVZ010000177 DACCVZ010000000
VERSION     DACCVZ010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.181"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            278..787
                     /locus_tag="IVW63_002903"
     CDS             278..787
                     /locus_tag="IVW63_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7861117.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="IVW63_002904"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="IVW63_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP7861118.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
BASE COUNT          756 a          378 c          418 g          618 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca
//
LOCUS       DACCVZ010000178         2134 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.182, whole genome shotgun sequence.
ACCESSION   DACCVZ010000178 DACCVZ010000000
VERSION     DACCVZ010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2134
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.182"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            24..248
                     /locus_tag="IVW63_002905"
     CDS             24..248
                     /locus_tag="IVW63_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAP7861119.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            245..1270
                     /locus_tag="IVW63_002906"
     CDS             245..1270
                     /locus_tag="IVW63_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP7861120.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            1460..1533
                     /locus_tag="IVW63_002907"
     tRNA            1460..1533
                     /locus_tag="IVW63_002907"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1494..1496,aa:Ile,seq:cat)
BASE COUNT          698 a          362 c          417 g          657 t
ORIGIN      
        1 actttattta gggagagaag aaaatgaata ataaaacgtt cgaagtacta aaatggttcg
       61 cactggtaat tattcccgca ctagctactt tcgtggggtt agttggtaaa gcgctcaatt
      121 ggcagtacac agatatctgt gttgtcatca ttactggttt tggcgcgttt ttagggagtg
      181 tgttgggtgt atcaaatcga acctacaaaa tgttctcggc tgaaagcgaa gaaggaggaa
      241 acaaatgaaa aagaaaatta ctattactgc gatgagcctg ttaacggctc tttttttatt
      301 acccattaat acgtttgctt atactattaa tgacgagtat aatttagcgc cgaatcaagg
      361 agactccaga ttagcaattc ctaacaaaat tattttgcac gaaactggaa tagatgcacc
      421 agcaagaaac gtagccgcca acatgaaaaa taattataac ggaagcaatt cttatactac
      481 agatgttatt ggtgacggtg ggattgttta ccgtgtgggt gagcaaggat atgtttcgtg
      541 gggagctggt aacgctaatc cttatgcgcc tgtacagatt gaattacagc gcacatatga
      601 taaagcattg tttgaaaaaa actatcgagc ttatattgaa tatacaagag atagtgcaaa
      661 aaaatatgga attccattga ctcttgatca aggaacttct ttatttacaa aaggaatcat
      721 ttctcatttg tgggtgacaa attatgtttg ggggaaccac acagatccat atggttactt
      781 atcgcaaatg ggagttagca aagaaaagct tgcttatgat ttagctcatg gatttaccga
      841 tgaaaatcca acaacttctg aaaacaagcc tgtcattgat ccaacacgag ctggtgcagc
      901 taatcctacg ctgacagatg gaacaaatca cgcccacatt gatcagtttg gggaaatcga
      961 aaacgcaaac ttgcatgtgg ctggatggca cattgctaac tataaatacg agtatatttt
     1021 cattatggac tacaatactg ggaaagaatt agctcgagta agagctgatg gaatttatag
     1081 accagatgta aaccaagctt ataatacttc tggaaatgtt ggttatcatg tatctttcaa
     1141 tatgcgtaat tttcctagta agaaagtcta tgtaatgatg cgggcaacga atgatccaga
     1201 gggaaacact aaaggcggtg cgcaagattt ccatgacaaa cgttggtatt taaatattcc
     1261 taaacgataa aaatagctcc tcgttgagga gcagtacata actatattga caactataaa
     1321 aattattcga taaaatagtg atgttatcgc atatcttcac tatcacccat aaatagtcac
     1381 actccaagct atgcgataac aggtttgttg ccacacattc tactggttga ttgtttatgg
     1441 ctttatgtgg caacaaccag tacccttagc tcagttggtc agagcagacg gctcataacc
     1501 gtccggtcgt aggttcgagt cctacagggt acattaacgt agccatttga atcgttctgt
     1561 gttagaattt ttttgaagag tattatacaa gctaaagctt ttcttcattg ccactcaaat
     1621 gagtggcttt tttatgtatc cttttatgga ttaatgaaag gatgtttcac atagttatac
     1681 ttctgtatat ttgaaaagtt ttactttgat ttttaaatag aaagacattt gggttaaatt
     1741 gtgagataat aataaagaag agtttaaagc gcaccccaaa ccacttcccc ataagtgtgt
     1801 tacgctttaa actcttttat atttgaagcc attaaaaagc ataccatatt tttgaaaaaa
     1861 agtgagaaaa aaggcttaca attggagtgg tagttaatta gtgacttatt tttgatttta
     1921 tagcactgat actataaaat atagatatca tcatattaca caatcttaat actaacttaa
     1981 aaaatatctc ctttcacaag tatggtgata aaattcgttc cgggctacct ttttaggtag
     2041 cctactttaa tctttatacc tttctggatc aacgaaagta tactttatat agtcataacg
     2101 ccgatgatcg ctacgtgcgt ccggcacgtc agtc
//
LOCUS       DACCVZ010000179         2108 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.183, whole genome shotgun sequence.
ACCESSION   DACCVZ010000179 DACCVZ010000000
VERSION     DACCVZ010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2108
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.183"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(525..890)
                     /locus_tag="IVW63_002908"
     CDS             complement(525..890)
                     /locus_tag="IVW63_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861121.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(966..1211)
                     /locus_tag="IVW63_002909"
     CDS             complement(966..1211)
                     /locus_tag="IVW63_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7861122.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1281..1535)
                     /locus_tag="IVW63_002910"
     CDS             complement(1281..1535)
                     /locus_tag="IVW63_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861123.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(1699..2022)
                     /locus_tag="IVW63_002911"
     CDS             complement(1699..2022)
                     /locus_tag="IVW63_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861124.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
BASE COUNT          792 a          360 c          370 g          586 t
ORIGIN      
        1 ttttagtcta ttttcagggg gggaacctta tgataaaaaa actattttta ctatcaatat
       61 taacgctagc aatggcaggt tgttctgact ctggcttagc aactgaactg atcacaaaat
      121 caactgaagc cacgacagag gagttaaaat gtggaaacga tcacagtgac tacagaggct
      181 taaatcgacg atgcatggga atattaggca gaagcaattg taagcatcga tgtagtaatc
      241 gaagaaggtg tagaagaagc aacagaaaaa tcaaaagaaa gatcaaaaga agcaatctgt
      301 gctgtgcatc gtatacagac gtcgaagatg cggtactttt aaaccacgtc aggagatgtt
      361 catttatgtc tagggaagtt ggcgatgaac caaaactaga gtacgctttt agttttgcac
      421 gtgaggatga agataaccct aaaacttacg acattttagc ttgatctaag atggttaaag
      481 ctttttaatg aagtaagagg agatagaagg cttttctagt tatattaggt aagataaatt
      541 cctttttgct ccaaatttgc taaacattct gctagataaa cttcatcgtg ttccggataa
      601 atcggcacgt tgcgctctac agtaggtaaa tcaaaaaatg cttcgcatga tttgccacga
      661 tacataggat ttttccactc tggtgctggg ctgtaaccac gtttttccat ttcatccatg
      721 acaagctgat gatattggaa taatctataa ggagaatagt gaaaaacata atccacagta
      781 gcatgtttct ttccccagcc atttcctctt aatgcacagc attcccgatg ttgtcctaaa
      841 agctgttgac gaggaagctt tgaaatcaat ttttcatgcc ataatcgcat agaaatgtct
      901 cctttatata tagattgtta accttagacg ttaaatgaaa aaaccagcac caaggctgga
      961 aaaaatcact tcagtttgct tgctgtttct gagcgaccaa ttaggtaatc aacggaaata
     1021 tcgtaaaagt cagcgatata gattaattca atgatgcttg gaatttcttc tccttcttcg
     1081 tacttacgat atttgaataa aggaatactt aacgcgctag aaacagctac ttgagataaa
     1141 gatcggccag ttcttaagaa attcagacga caacgtaaag tatccagtaa aatagcttct
     1201 tcgatactca tttaatcacc tttcattata gtagaatagt tataatgact atagaaagct
     1261 acacatgcaa tcaatagtac tcaatgtttt ttatttaaac gtatcaaata aagaatgacg
     1321 atcaataaag acaaaaccag tcctgataat tcttctataa aaacactatc gggttcaaag
     1381 tagttgtaat taaaaacttt ccacataaag tagatagccg gaagagtcaa aatagctaaa
     1441 taaaaccgtt ctttgttcca attcataaga taaacaatac ttgcgaccag tgcgaccgca
     1501 ggcacccaaa acaaaactct caccaacgta atcatgtaac ggactcctca acgattcata
     1561 taataaaaga taacatgtta ttgcatacat cacaaatgaa atgctaggaa aataaaagaa
     1621 gaatagatca atgaaaaatg aaaaagcaga acagttttct gctgataagc aggaactgtt
     1681 ccgctgaatg tgtcttatct atcgagaaaa aatcaatgga ttgatatcta agtaattcaa
     1741 tacatataaa aagaggacga tcgcattcac taaaaaggaa agaatgatga tcccatagcg
     1801 aatggaaaca tatttaacaa atacttttgt ttgaatacgg gcatatcttt ttcctttata
     1861 gctgagcatc atgacaagaa gcaaaagggt aatcacacct tgaaaaatca ttccaataaa
     1921 cagaattcct gaggtttgat aatttaattg gagaaaataa gctgctgccg caactaaatc
     1981 gaataaaatc gcaataaatg gcaaaataat cactcctaac attgagaata aataaaagaa
     2041 taacattttt tctaaaataa gcaaataaaa attaaagtaa caaaatagtt atgacacaag
     2101 taaaagaa
//
LOCUS       DACCVZ010000180         2056 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.184, whole genome shotgun sequence.
ACCESSION   DACCVZ010000180 DACCVZ010000000
VERSION     DACCVZ010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.184"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            493..714
                     /locus_tag="IVW63_002912"
     CDS             493..714
                     /locus_tag="IVW63_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861125.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="IVW63_002913"
     CDS             715..972
                     /locus_tag="IVW63_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861126.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKVAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="IVW63_002914"
     CDS             complement(1108..1710)
                     /locus_tag="IVW63_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAP7861127.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKLRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="IVW63_002915"
     CDS             complement(1777..1932)
                     /locus_tag="IVW63_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010001600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7861128.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          462 c          314 g          602 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggtggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaag cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatta ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DACCVZ010000181         2055 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.185, whole genome shotgun sequence.
ACCESSION   DACCVZ010000181 DACCVZ010000000
VERSION     DACCVZ010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2055
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.185"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..263
                     /locus_tag="IVW63_002916"
     CDS             <1..263
                     /locus_tag="IVW63_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAP7861129.1"
                     /translation="IEIHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEM
                     PESANDMYEKELKYFFENVVTGKENWNDLYHANEVLKIAEEK"
     gene            264..1016
                     /locus_tag="IVW63_002917"
     CDS             264..1016
                     /locus_tag="IVW63_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAP7861130.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            1021..1968
                     /locus_tag="IVW63_002918"
     CDS             1021..1968
                     /locus_tag="IVW63_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAP7861131.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYNKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT          721 a          271 c          402 g          661 t
ORIGIN      
        1 ttatagaaat tcatttagat tattttggaa gagttcctac aagaaaattt caattgttta
       61 ctttagatga atgtatcaat gttgacttat taaataataa aataagtttt gaagaaaaca
      121 ttgttaaaga aatgcctgaa tctgctaatg atatgtatga gaaggagttg aaatatttct
      181 ttgaaaacgt agtaacaggc aaagaaaact ggaatgattt atatcatgca aacgaagtat
      241 tgaaaatagc tgaggagaaa taaatggaaa ttttatttac tatttgtggt agagctgggt
      301 ctaaggggtt taaaaataaa aatttgaaat atttggcagg aaagccccta gtccatttcg
      361 ctttagcaat gatagatatc tatcaacaaa aacatcctga acataattgc acgacttgtt
      421 tgaatacgga cagtaatgag ttagtagaat tgacgactaa gttaaatccg tctgtgaaaa
      481 ttgtagaacg taaacctgaa ttagctacag atactgtagg gaaaattgaa gtgatacgtg
      541 attcattctt acaactagaa agagaagata atatatttga tttaattata gatttagatt
      601 tgacttcacc tttacgtgaa gtttctaatc ttgaagaatt aatagatgaa catctaaaaa
      661 atttagataa agacgtctac ttttcagttg tttctgcaag acgtaatccc tattttaata
      721 tggtaaaaag aattgaaaat gaagttacta tagttaataa atcaagatac acatctaggc
      781 aacagacacc tgaagttttt gaaatgaatg cctcaatgta ttcttttaaa cctgaatttc
      841 taaaaaaaag taattatatt tttgatgggc aatgtgggat aataaaaatg agagattatc
      901 taattttaga tattgatagt gaagaagatt ttaaatggtt agaatttttg tttcctaaat
      961 ttttagaaga ttcttcggag cttcaagata tctataatta tttatatcgg aggtaaaagg
     1021 atgagctgtt atcttatcac cggtggggct ggcttcattg gttctacctt agccaatcat
     1081 ttaggagaag aacatgtggt aatcgtcgtc gatgacttat caatgggaaa agtagaaaat
     1141 cttgatatga cgaaaaatat cacttttatt gagggagatg tcgctgagaa atccttgatg
     1201 gaagagatca tgaaagctaa taaatttgat tatatctttc atttagcagc agttgctagt
     1261 gtggcagatt cagttgcccg accagtagaa acacatcgtg tgaattttga aagtgtatta
     1321 atgattttag aattgatccg caagtatcaa cctgatttaa aacggatcgt gtttagttct
     1381 tcagcggctg tttatgggga tgaaccgact ttaccaaaaa aagaagagtc cgtgattcgc
     1441 ccattgacgc cttatgcggt tgataaattc gctgcagaac aatatgtgct agattattgt
     1501 catttatatg atgtacccgg tagcgcagtt cgttttttca atgtctatgg tccaaatcaa
     1561 aatccgaatt ctccatacag tggtgtgatt tctattctcg tagatcgcta taataaacaa
     1621 atcgtaggag aagcaacttc atttacatta tttggtgatg gaagccagtc tagagacttt
     1681 gtttatatag atgatgtaat ccaagcatta cttttagttg cgaatgagga agctgcactg
     1741 gggaaacaat tcaatgttgg aacgggtaaa gcaaccacac ttttggaatt gattcatgca
     1801 atcaatgaaa ttctcggtgt agaattgaca cttgaataca aagaagagcg ttcgggtgat
     1861 atccatgact ctctagcaga tattactaag atccagtcaa ttggctatca accgaaatat
     1921 ggtattttaa gtggaatgac taattatttg aaaactgaaa tcaattaaaa catactaaga
     1981 taagattaga gggtaaattc aggctctttg tcaataagga ctgatgagtt ttgtaaaatc
     2041 aaatctggga tagaa
//
LOCUS       DACCVZ010000182         2004 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.186, whole genome shotgun sequence.
ACCESSION   DACCVZ010000182 DACCVZ010000000
VERSION     DACCVZ010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2004
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.186"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..378
                     /locus_tag="IVW63_002919"
     CDS             <1..378
                     /locus_tag="IVW63_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAP7861132.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /gene="yfcC"
                     /locus_tag="IVW63_002920"
     CDS             426..1826
                     /gene="yfcC"
                     /locus_tag="IVW63_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAP7861133.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..>2004
                     /locus_tag="IVW63_002921"
     CDS             1859..>2004
                     /locus_tag="IVW63_002921"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP7861134.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAFT"
BASE COUNT          555 a          340 c          432 g          677 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt ttac
//
LOCUS       DACCVZ010000183         1979 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.187, whole genome shotgun sequence.
ACCESSION   DACCVZ010000183 DACCVZ010000000
VERSION     DACCVZ010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.187"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(325..528)
                     /locus_tag="IVW63_002922"
     CDS             complement(325..528)
                     /locus_tag="IVW63_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861135.1"
                     /translation="MSQLGKCYSLSKSNRKVYTLFISDSVKEGFTLGFSISFKKGTKN
                     TSISHNNRELTDSQKINGLSGRK"
     gene            complement(728..1744)
                     /locus_tag="IVW63_002923"
     CDS             complement(728..1744)
                     /locus_tag="IVW63_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAP7861136.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          559 a          459 c          308 g          653 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaca ttttcctaat tgtgacatgg ctgtcacaat
      541 tccaaatgct ctccgagggt attcgctgtc acaagtgaca acgaaaaaag gagccgaaag
      601 cgtgtcacgc tctcaactcc ttttacgctt tattttgctt cacgcaaaat aatcgcttat
      661 cgtaaatcca cgtcactaaa cattgacgta aatttactct cactcatctg acttttctta
      721 ttcggtatca cttctctgtc acatccaacc ccaaaagcca cgtatccaat tcttttttta
      781 attcgtctgc agattcctta aaagtctctc gtaaatgatt cgttaactca tcattttgac
      841 tttcttgctt cagcaaattc cgatatttat attttgtatg tctagcaatt atcgaccaat
      901 tagaaggctc agctatcaaa ccatcaataa ctattttatc aataggtttt atatcaatcg
      961 gcaaaaaatg cgggcttgca aaactatcta agctttcctg aaccatcgca tgccaatccg
     1021 ttgctttgcc acgtcttagc tgcatttcta accgccacca cgtatcgatt tcttttggca
     1081 cgattacttt ttttcgttcc tgctctagct ttttgttgta cagtcgcact tggcgctcac
     1141 tggcacgact gccccagtac gctgtttcta gcttgccaga acggccgtag attggcttaa
     1201 aagaaatcgg gtctacaata cgatactgag taataaagtc atccggcaca tctacaatat
     1261 cgcaggcaat atccgcccgg gaaaaatgcg gatctaaaaa taggtcatga atgaatcctt
     1321 tcatggaact agctaaaaac tggcctatct tattcggatt aaaatcaata cgaccttttc
     1381 cttcatgaaa tttaagtatt tcgatatacg caatatcttc tccatattga tcgaataatt
     1441 gccagccgtt tatcccaact gatttcaaat atccctgatt ttcgttcaaa cgcattaatt
     1501 gctcgaaatc gacaaaaaca actccatttt tcgtccaata agctatggta tcattcagtt
     1561 ttccgacaat tgtaattcga tcaatcgacc aatttaattt taggggggtg gtcgtacctt
     1621 gcacacttaa ccgcctgtta gaaatacggt taagtttttc gagctgattt atcgttgttc
     1681 ttttttctgc ccctcgacct tcaatttttg attgaatttc actcaactga ttttcatttg
     1741 ccattttcgt cctccaaacg aaaaaagaga cttttggaaa gaatttccag agttcacgta
     1801 accctaaaaa ttcatatcca aaaatctcta gcttgaagaa acctaaaaat attcgtataa
     1861 tgaacctgag ttacggagct aggtgaagta gtttccgtaa atagtcgaga gtgttagcgc
     1921 actgctcggc ttttattttg ctcttttttc tcgttttctt tgattatagc actcctcct
//
LOCUS       DACCVZ010000184         1820 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.188, whole genome shotgun sequence.
ACCESSION   DACCVZ010000184 DACCVZ010000000
VERSION     DACCVZ010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.188"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            275..1753
                     /locus_tag="IVW63_002924"
     CDS             275..1753
                     /locus_tag="IVW63_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP7861137.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
BASE COUNT          661 a          253 c          325 g          581 t
ORIGIN      
        1 taaaagagca ggacggtggc cgtcctgctc ttttttgtgg ttgtttacgc aaatggcgca
       61 aatcttgtac attttaacac aataaaacaa aaaatataga atatttcctc ataaattttt
      121 ccattttttg caatattctc aaaaaaaaga taaaaaatga gaataactga tgaaaaaaca
      181 agcataatcc atcataaaat cagtataggt gaaaagatga actttcatct gcatatcaag
      241 taattggtat gaggcatttt ttgaggtgta ggatatgaag ttggattacc ttatagaaga
      301 ggaagataga gaaaaactgc tgctagctag atatttagaa tttgagaaaa agaattatgt
      361 agtgctgcct aagttatatg aaacattagg tttgtctaaa tttaaaacaa gaaattatat
      421 catagaatta aataaagaat ttactgaatt caaaacaaag ccagagatcc aaatttcaga
      481 agaagcagag atccatgtcg aacgtctgaa tttgacggat atcaaaaatt taagaagaat
      541 ctactttcaa cgatcaaaaa ttgctcgact gttaacggag atcgtggatt caaaagtaac
      601 gatcgaaaaa tttgcagaga atcatttttt aagcatatca agagcctatg taaaaagaag
      661 agaattagtc tcttttcttg aacagcatca aataaagtta aagaaaaaca tattagttgg
      721 ggaagaaata aacatacgga acgtattatt tggggtatat ttcggggtct ttaatggttt
      781 ttctatgcca tttagagaaa gcgtcatgaa tgaagcaaag agtatcgtgc aatattttga
      841 atatctgttc aatttaaaac tgtctgcaac aaaacgaatc aaattcaatt tgctaaccac
      901 tattagtttg ttgagggcct atgggaatca accaatcgga aaacgtttct tttcagatga
      961 atactttaag agctcagaag gaatgaagat catcaaggat ttatcacata tttcttttct
     1021 tcatatccct aaagagcaga tcattgatga gatttcttat atcatgttgt ttttgatcac
     1081 ggaagaagaa tttgaattag atggcgcatt tggacttgcg gaagctcatt ttcatgatat
     1141 ccacatgatt agtcaaaaaa tgtcagtgga attgattgat caattaccat tttcgattga
     1201 aatctctgaa gaagaaagac tatatatacg aaaagaactt cgtatgggta tgatgcatgt
     1261 caatcgaaaa aattggatat tcgactttga gatgactagc tttacgtcta aaaagcagct
     1321 acagtttttc ttcgagacgt atccaatatt cagtacagca atccaaaagg tcatacaaga
     1381 gaataaacgc tatttcttgg gaaaagatga acgtttcatg attcgcttat tttatgatta
     1441 tctcttttta ttggtcggta tttgtccggt atcatatttt gaagcaccga ttcatgtctg
     1501 tattgatttt tcgcaaggat ctgcttatac cgattacatt atttctcaag tgaaaggatt
     1561 taaaaattac aatattgtga ttgagagtcg aatcacttct cgtacgaata tttatttatc
     1621 tgattgttta cttgaaaaat ttaataaaga acagataatt tggaaaaatc caccgactcc
     1681 agatgactgg gaatattttg gaaataccat catcagagaa aaaaatagac atttaactga
     1741 aaaaatcagc tagtatttat ggatggcagc tttgtctcac atatttatta gctgatttat
     1801 gtttttttca aagaaaaggt
//
LOCUS       DACCVZ010000185         1773 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.189, whole genome shotgun sequence.
ACCESSION   DACCVZ010000185 DACCVZ010000000
VERSION     DACCVZ010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1773
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.189"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            133..507
                     /locus_tag="IVW63_002925"
     CDS             133..507
                     /locus_tag="IVW63_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP7861138.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(621..1250)
                     /locus_tag="IVW63_002926"
     CDS             complement(621..1250)
                     /locus_tag="IVW63_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP7861139.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1384..1456)
                     /locus_tag="IVW63_002927"
     tRNA            complement(1384..1456)
                     /locus_tag="IVW63_002927"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1421..1423),aa:Thr,seq:ggt)
     gene            1670..1743
                     /locus_tag="IVW63_002928"
     tRNA            1670..1743
                     /locus_tag="IVW63_002928"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1704..1706,aa:Asn,seq:gtt)
BASE COUNT          618 a          258 c          311 g          586 t
ORIGIN      
        1 gtctacactc tgagatgtaa gaaatatcat aagatatttc ttacatcttt ttgttttgag
       61 caggacttta gataatttta ttaatatatg ctagcatgct tttgtaagaa aaagaaagag
      121 ggcgtattag ttatgtatct taaaattacg gaacaagcac aagaaagatt acaaaaatat
      181 attgatgaag gcgcaacagt tatattggat ttagatgatg gcgttgggga atattctaaa
      241 atgggtgttt gctctttaga tactagtttt cgtttacttc ttcttgataa agaacagaga
      301 aaaaatgatt ataaactcca attagatagt gatattgggg atgtttatat aaaagattat
      361 tcaaaaatgt acatggatga acatatgacc ctttctttag atccacgtct aggtgtattt
      421 actcttgaaa gcccaagtgg ttctttagac agtcatgttc aattagtaga tctacgacca
      481 gaaaaattct ctggaataaa acaataactt tctctctatt gtccataaaa ctagtctcaa
      541 tcaagctgta ttgaaaaaac aagacaacat tcttaccatg gtaaataaaa agacgacaca
      601 ttttgtcgtc tttttttaaa ttaactattt tcgataaaag atcgcatagc ttgtgccatt
      661 atttctggct tttctctatt caattcatgt tttccgtttt taataaagag tagccggcca
      721 ttcgttgaaa gtttatataa acgttttgct gctggtttat tcgcatgatc tttggtaccg
      781 cataaaatca atttaggaag tcgtgatgta cgaagctgtt ttttgcagtc taatgtttca
      841 agtgaacgaa gtagggtaag ggtttgtttt ttagatagac ctaatttttc aaatatctta
      901 gaaggtacgc agtaaaaata aatattctgg aaagtaagca ataagcgatt aggagactca
      961 aattgtggag cgactaaaac aacctttttt aaatatggag aaggagttgc aagatagttt
     1021 aaagcaataa cagcgcctaa agataatcca cataaaataa aaggttcctt tatctgattc
     1081 aattgtactt cgatgtattt ggttaagtcg tctaaagtag cagtgtctgt gctgtttaaa
     1141 tgattgaaca atgaaagact tttgcaagaa taactattgg gtagataaga gattacatct
     1201 ttccatgatt gttcgtcttg gcctagacca tgcaaaaaaa caattttcat attgctctcc
     1261 tttttatagt tatcatatag actttctttg tactattaaa atataaacat tcatttctta
     1321 cgtcataaaa taaaaaaaca gcgcagacac attgttaaac caacatgttg cactgtttaa
     1381 ggaagccact tgccgggctt gaaccggcga cctcttcctt accatggaag cgctctacca
     1441 gctgagctaa agcggcatta tcattaatac aaataatagg ataacgaata ttaatgtatt
     1501 tgtcaacaga attttttcga aaaaatgtgt ttctctaata ggaaaacaga ttttagaaaa
     1561 aataaaaata acaaaaaatg cgaacggttt ctttgataat ataataaaaa aattcaaaaa
     1621 aagtattgcg ttatttagaa gaaattgata ttatattcat gtacttgatt ccggcatagc
     1681 tcagttggta gtagcgcatg actgttaatc atgatgtcgt aggttcgagt cctactgccg
     1741 gagtaaataa agcttatgca aagaaaaaga aat
//
LOCUS       DACCVZ010000186         1751 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.190, whole genome shotgun sequence.
ACCESSION   DACCVZ010000186 DACCVZ010000000
VERSION     DACCVZ010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1751
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.190"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            949..1422
                     /locus_tag="IVW63_002929"
     CDS             949..1422
                     /locus_tag="IVW63_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAP7861140.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="IVW63_002930"
     CDS             1431..1658
                     /locus_tag="IVW63_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7861141.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          588 a          272 c          260 g          631 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaaaa atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt t
//
LOCUS       DACCVZ010000187         1738 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.191, whole genome shotgun sequence.
ACCESSION   DACCVZ010000187 DACCVZ010000000
VERSION     DACCVZ010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.191"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            40..1533
                     /gene="guaA"
                     /locus_tag="IVW63_002931"
     CDS             40..1533
                     /gene="guaA"
                     /locus_tag="IVW63_002931"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAP7861142.1"
                     /translation="MITRRIREFGVFSELMSHRITAEEVKAMNPKGIILSGGPNSVYD
                     EKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGKVKPAKNREYGKAELEITSAEAALF
                     QNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCPIASIQNAERKMYGIQFHAEVRHSE
                     YGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIREQVGDKKVLLGLSGGVDSSVVGVL
                     LQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGKFGLNIIKVDAKERFLSKLAGVSDP
                     EEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQGTLYTDVIESGTETAQTIKSHHNVG
                     GLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFPGPGLGIRVLGELTEEK
                     LEIVRESDAILREEIANAGLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSI
                     DGMTADFARIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE"
BASE COUNT          529 a          357 c          369 g          483 t
ORIGIN      
        1 aaaattatcg tacttgatta cggtagtcag tataaccaac tgatcactcg ccgtattcgt
       61 gagttcggtg ttttctcaga gttgatgagc caccgcatta ccgcagaaga agtaaaggca
      121 atgaacccta aaggaatcat cctttctggc ggaccaaaca gtgtttatga tgagaaggcc
      181 tttggtattg atgaaaagat ttttgatttg gggatcccag ttttaggaat ctgttacggt
      241 atgcagttga ttacttataa attaggcgga aaagttaaac cagccaaaaa ccgtgaatac
      301 ggaaaagcag aattggaaat cacttctgca gaagcggccc ttttccaaaa cactcctgaa
      361 aaacaaaccg tttggatgag tcatggtgac ctagttaccc aagcaccgac tgatttcgat
      421 gtcgttgcta ccagcaaaga ttgccccatc gcatcgatcc aaaatgcaga acgcaaaatg
      481 tacggaatcc aattccatgc agaagttcgc cattccgaat atggaaatga cttgttgcgc
      541 cattttacac tagatgtctg ccaatgtact ggtgactgga caatggataa cttcatcgac
      601 atggagatcg caaaaattcg tgaacaagtc ggtgacaaaa aagttttatt aggcctttca
      661 ggcggagtag attcctctgt tgttggtgtt cttttacaaa aagcgatcgg cgatcaatta
      721 acatgtatct tcgttgatca cgtattgttg cgtaaaggtg aagcagaaca agttatggaa
      781 agtcttggcg gaaaatttgg cttgaacatt ataaaagtcg atgccaaaga acgtttctta
      841 tcaaaacttg ctggcgtgtc tgatccagaa gaaaaacgta aaatcattgg aaatgaattt
      901 gtatatgtct tcgatgatga agcaaccaaa cttgccggtg aagaaggcgt ttctttcctt
      961 gcacaaggaa ccctttatac cgatgtgatc gaatcaggaa ctgaaactgc ccaaaccatc
     1021 aaatcacatc acaatgtagg tggattacct gaagacatgc aattcaagct gatcgagcca
     1081 ttgaacacat tgttcaaaga cgaagtacgt gaattaggta cccaattagg catgcctgac
     1141 agcatcgttt ggcgccaacc attccctgga ccaggcttag gtattcgtgt ccttggtgaa
     1201 ttgacagaag aaaaattaga aatcgtccgt gaatcagacg ctatcttgcg cgaagaaatc
     1261 gccaatgccg gtttagatcg cgacatctgg caatacttca ccgtcctacc aggcattcgc
     1321 tctgttgggg ttatgggaga tggccgtacg tatgactaca ctgtaggtat ccgtgctgtc
     1381 acttctattg acggcatgac cgctgacttt gcccgtatcc cttgggaagt cttgcaaaaa
     1441 atcagtgtcc gtatcgtaaa tgaagtcgca cacgttaacc gtatcgtgta tgatattacc
     1501 agcaaaccac ctgcaacagt ggagtgggaa taaagagcca acataatatg gatgaggaat
     1561 acctataaat caacattatt caattactaa agttcctgat tttcgtaaaa aataagatgg
     1621 tttcctacca ttttccctac caaagccctt gttagattaa ctactaacaa gggctttgct
     1681 tttattcact acctttattt tcctattgaa ttagcttttt atctaatcag atttttag
//
LOCUS       DACCVZ010000188         1711 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.193, whole genome shotgun sequence.
ACCESSION   DACCVZ010000188 DACCVZ010000000
VERSION     DACCVZ010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1711
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.193"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            54..476
                     /locus_tag="IVW63_002932"
     CDS             54..476
                     /locus_tag="IVW63_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861143.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            486..689
                     /locus_tag="IVW63_002933"
     CDS             486..689
                     /locus_tag="IVW63_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861144.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            900..1484
                     /locus_tag="IVW63_002934"
     CDS             900..1484
                     /locus_tag="IVW63_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7861145.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          603 a          242 c          311 g          555 t
ORIGIN      
        1 ttaagattta ttaagaaaac gttttcttat ttttgatttc gaggtgatag acaatgaaaa
       61 ataagtttat tttatcttta ggtattttaa ctattggaat tagtgtaact ggaactacaa
      121 ttcctacatt tgctgatagt acaaatgaac caactactgt agtagataat aaccaagaat
      181 taactccttt agataggaac ggaatagcca ttggtaaccc aactaacgac ttaactgtta
      241 ctgaaaatta tttaatagtt tctccattac ttgctcgagc agcttctaaa acgatacgag
      301 tgacaggaac gatgattttt gataaagttg gttggccttc tagacctcct caatcacgga
      361 attggaaaga aaaaagaaat ggttattggt actatggaaa attgtattta caaagttata
      421 aatcagctgg aaacaattgg attgcgactt attcaggaac cttaactaga aagtagggat
      481 tttttatgcc agaatttgtg aacacaccaa atttttatca agatagcgat attctaagta
      541 aaattaattt accgaaagaa gaatcagctt tacaagttca gcgaacttta caggagacac
      601 aaaaaattca aaaatcaatt tctaatctag aagattctga agaaaaaaga aaaaaaagag
      661 accaaaaaac atatcaaaaa gaaaaataat gattttaaaa aaagagtgtc tagtcgacat
      721 tctttttttc taattgaaag tgttcataaa atcacccatt tctggacact ttcttttttt
      781 gctttatttt tcaaaaaaac aattcatttc atgttcataa acccataaca atatctatgt
      841 tcagttaaac tatatggata aagttatgtt acaataaaat taatgaagga gtgatttttt
      901 tgaaaatagg atacgcccgg gtatctactg gtttacaaaa tttggattta caagaagaca
      961 gcctaaataa atttggttgt gaaaaaattt ttactgatca tatgagtggg gcaaaaagta
     1021 atcgaccagg attagaaatg gccattgatt ttgttcgctc tggcgataca cttgtcgttt
     1081 ggcgcttaga tcgtttaggt agaaatatgg aagatttgat ttcaatcgtc aatcgactga
     1141 atgagcgtgg tgtgagtttt catagtattc aagaaaatat tacgatggac aaatcaagtt
     1201 ctacaggaca gctcatgttt catttgtttg cggcatttgc agaatttgag cgtaatttga
     1261 tcctggaacg atccgcagca ggacgagcag ctgctcgtgc aagaggacgg tttggtggtc
     1321 gtcctgaaaa attgtctgaa caagatttgg aattactgaa gactttagtg gatagcggta
     1381 cacctattaa gactattgcg gaacggtgga acgtctcaag aaccaccatt tatcgttatt
     1441 tggcaaaaat ggaggagaaa aatggaaaga caaattctca ttagtttttg tcatttaatg
     1501 ctgaaaattt ttgccattta tctagaaaag tgacaatagt atgagaattt tttgtaagtg
     1561 tctactgata acttattctc aaatgttgta aggattttat tcatttgtta atattaaaga
     1621 acggaactcc aaaaaagtcc gtactctaat ttgcagtctc tcactctttt agagtgagag
     1681 tttttattag attttcaaat taattagtaa a
//
LOCUS       DACCVZ010000189         1708 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.194, whole genome shotgun sequence.
ACCESSION   DACCVZ010000189 DACCVZ010000000
VERSION     DACCVZ010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1708
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.194"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..250
                     /locus_tag="IVW63_002935"
     CDS             <1..250
                     /locus_tag="IVW63_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP7861146.1"
                     /translation="NDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDEFF
                     IQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            complement(370..1233)
                     /locus_tag="IVW63_002936"
     CDS             complement(370..1233)
                     /locus_tag="IVW63_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP7861147.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
BASE COUNT          492 a          355 c          302 g          559 t
ORIGIN      
        1 caatgatatt gccatttatt tcgctgatcc aggaacgccg tctcaaagag gcctaaacga
       61 gaattctaac ggattgttac gtagagatgg tttattgaaa tctatggatt tcaattcagt
      121 agatgaattt tttattcaat ctgtcgcatc taaacgaaat aatattccta gaaaatcact
      181 ggattatcga acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa
      241 cttaatttga caattaagaa aataaaaaaa cagcgacctc taagagatag gatgctcatc
      301 tatcttttaa gagtcgctgt ttttgttaca atcaatttct gggctttttt acagaatgag
      361 ttactgcttt tatcgactga ttcccatcga aaaaatcgcg atacagccat agcctgtgtg
      421 actggcgatc gttggtccta agggataaag cttcacatct ttcatcttta tctgctcttc
      481 caaaagccgt tttgccttct ccgcgctctc tagatcccca gcgtaagcca cataaacgat
      541 ttgatcaagt ggtgcaacga ttgtttttac cgtctcattg acgattgtct ggatcgactt
      601 gtttcttcct cgaactttgt caacattcgt cagccttcct tctttatcca ccgtaataat
      661 aggctttaca ctcaatagac tgccaagagt agcacttgct ttggaaatcc taccgcctcg
      721 ttctagatat ttcagatcgt ctactgttac ccatgaatgg actttcaaat aattactttc
      781 cagccactct agggtttctt cgatgctttt accttctttt ttcaatctta cagcttccaa
      841 tactaaaagc ccttccccaa tacttgcagc ttttgtatca aaaacataga tctcagggtc
      901 ttcatattct tccttcagca attcaaccgc ttgaagcgca ctactgtaag agccgcttaa
      961 tccactggaa aaagccacat ataaaacagg aatctgtttt tccgcataag aacggaaaaa
     1021 ttctaaatat cggccaacat tgatttgtga tgtcgtaggc atcgcaccat ttttcagctg
     1081 attcatgtag cggtcataat tgaatgtctt tccgaggtca tctactaact cttgatcatt
     1141 caattggaga ttcattgata aaaaatcaac tttttctttt gctaatacat ggtatggcag
     1201 atcacaacaa gaatctgtta caatttgata cacatttttc aaccccttct cgttacattt
     1261 tacccttatc gtctattata gcaaatctct tgcgctagac acactttaac cggtttattt
     1321 tcgcaagttc taatcaaaat aagaggttgt gacagaagtg gtcagcttca agaaataaga
     1381 aggaatttac gaaaattgct tctcaaattt ttgtgaaatt tcggcttatt tccgtagaag
     1441 ctacttctgg aacaccgtga atcagaggtt gtgaaatcag cgttttgacc tgagtattag
     1501 agaaaaaaac ggaaaaaata gttcctcata ttttgccgtt ttttgagcta ataccgaggg
     1561 tcagctgatt gaacaccgtt taccaagagg ttgtgagcct gccgtttagc tccgagtcac
     1621 aaggaacaat ttcaaaaaac agcttctcat gtttgttgaa tattgtgact tgtgaccgag
     1681 gagttggcag gagaacaccg tttagtgg
//
LOCUS       DACCVZ010000190         1667 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.195, whole genome shotgun sequence.
ACCESSION   DACCVZ010000190 DACCVZ010000000
VERSION     DACCVZ010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.195"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..156
                     /locus_tag="IVW63_002937"
     CDS             <1..156
                     /locus_tag="IVW63_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HAP7861148.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
     gene            175..1452
                     /locus_tag="IVW63_002938"
     CDS             175..1452
                     /locus_tag="IVW63_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP7861149.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1462..>1667
                     /locus_tag="IVW63_002939"
     CDS             1462..>1667
                     /locus_tag="IVW63_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7861150.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNED"
BASE COUNT          692 a          146 c          284 g          545 t
ORIGIN      
        1 gataaggata agtgtattaa ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat
       61 tcagttgaga attgcaatca tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt
      121 ccagtggatg caattagtta tggagtaaga aaatagagag gagtagttag gaaagtgata
      181 aaaaatgcta tagcatatat tacaagaaag aaaaatagaa ctttaataat ttttatcata
      241 ttaactatag ttctttcttg cttgtattct tgtttaacaa taatgaaatc aagcaatgaa
      301 atagaaaagg ctttatatga aagttctaat tcttcaatat caataacaaa aaaagatggt
      361 aaatatttta atgttaatca atttaaagat attgaaaaat taaaagaaat tgaagaaaaa
      421 ataattcaat atgatggatt agcaaaacta aaagatgcta aagtagttag cggagaacaa
      481 agaataaata gagaagattt atctgacgaa tttaagaatg ttgtttcact cgaagctaca
      541 aataatacta aaagaaatat tttatttagt agtggagtat ttacaattaa agaaggtaaa
      601 aatatagaag aaaatgataa gaattcaatt attgttcatg aagaatttgc taaacaaaac
      661 aatctaaaat taggtgatga agttgatctt gaattactag atattgaaaa aagtggaaaa
      721 ataaaaagtc ataaatttaa aattataggg atcttttctg gtaaaaaaca ggaaacatat
      781 acaggattat cttctgattt tagtgaaaat atggtgtttg tagattattc aacaagccaa
      841 gagatattaa ataattcaga aaataatgaa attgcaaata aaattttaat gtattctggt
      901 agtgcagaat ctacagactt agccttaaac aaattgaaag agcttaaaat tgatgagtca
      961 aagtattttg ttgaaaaaga ttctaatgcg tttgaagagt ctttagagtc agtgagtgga
     1021 ataaaatata taataaaagt aatgacttat tctattatgt taggtgggat ggttgttctt
     1081 tcattaatct tgattctatg gttaagggaa agaatttatg aaataggtat attcttatct
     1141 attggaacat ctaagataca aattataatg caatttatat tcgagttaat attcatatcg
     1201 ataccaagta taatatcttc cttattttta ggaaatgtat tactaaaagt aattgtagat
     1261 ggattcatta actcagagga ttcaatgatt tccggtggaa gtttaataaa taatagtagt
     1321 tttatgtcaa atataacaac acttggacaa agttatttaa tattaataag tattattgtt
     1381 ttatcagttg tatttgcttc ttcattaatg ttaatcaaga agcctaaaga aatcttatca
     1441 aaaataagtt aggagaaaat aatggatata ttagaaataa agaatgtagc atatagttat
     1501 gcaaattcta aagaaaaagt tttgtcagga gtaaatcaaa aatttgaact tgggaagttt
     1561 tatgcgatag taggaaagtc aggaacagga aaatctacac ttctttcctt acttgctgga
     1621 cttgataaac ctcaaacagg aaaaatattg tttaagaatg aagatat
//
LOCUS       DACCVZ010000191         1656 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.196, whole genome shotgun sequence.
ACCESSION   DACCVZ010000191 DACCVZ010000000
VERSION     DACCVZ010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.196"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(101..586)
                     /gene="vanZ"
                     /locus_tag="IVW63_002940"
     CDS             complement(101..586)
                     /gene="vanZ"
                     /locus_tag="IVW63_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAP7861151.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(739..1650)
                     /locus_tag="IVW63_002941"
     CDS             complement(739..1650)
                     /locus_tag="IVW63_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HAP7861152.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT          532 a          317 c          224 g          583 t
ORIGIN      
        1 acacctacgg gcgagtttcc ccacatcccg ttttccatct aatccaattc attcaatatc
       61 tttatgtgta tgaaagatca gattgcttga tttagacatc ttacacgtaa tttattctta
      121 aatgggtacg gtaaacgagc aataatacga gcaaaagtat acctacaaaa ataataactc
      181 tgtctaattt tttttgattc atatgcttat tgcttaaacc atataatttc agtccaagaa
      241 agcctccaac agtatttgta attacatctg ttatgtctgt cgctccaata gcgaagataa
      301 attgaattat ttcaaaagta agacttaaaa ccagtacaaa agcaaactta ggtaaaaatc
      361 cgatttcttt aaaattgaca ttcaaaagca agccaaatgg aataaagatt ataacattat
      421 ctatcatctc tctgaaattc ccagtagcag taaatggagt caagttaaga cttctttgat
      481 gataattaaa tactgataaa atattgtatt gtaatttgaa taacactaac cagattagtg
      541 tcactaaata taaagctagc aatcctctag ataatatttt tcccaatata atttcctcta
      601 attcttttgt ttaagttgta tcattagtat agcaatgtcc tagttaacgt gggttttaaa
      661 ttaaaaagct aacgttaccc caaaagtgct agtacaataa tgctgttcat taatttcgtt
      721 ggtttcattc cgccatcctt acctccttga attagtatgt gttgatccgg gaaacactgt
      781 cacaattaca ccgtctatat tgtttcctga tatctcataa cgaagattag tcggcacatg
      841 aatggtggta tttttagtaa caggataata aaagatctca tatttttccc catttacact
      901 aacagaaatg gttttttctt cttttaggta atccatatat tcctcgagaa cgaaattctt
      961 ttctttcata atcgcactat gtggtaaacc aacatagcga atatgccatg gttcatattg
     1021 aattcctgtt aactctgttt tgtcctctgg ataacgtaaa atgaacccgt atttccaagc
     1081 attttcttct atccactttc cttcaggggc tcgttccatt ttcgtcaagc ttgatcctac
     1141 atctagtgat aaacctgaat tatgctcact ataacctgct ggtaaggcat actcagcccc
     1201 catttcttgg taaagcacac tttgctcatc aaagtctcga tagccactat taataataaa
     1261 atgactaacg ccacccttta cagcatcatt gaccatctct gaaaattttt gtgctatttc
     1321 ttttgacata taaatattac tatcaagcaa cccgtatcca tttattaatt cgtcatgttt
     1381 agataaattc acgatatctg acttcacact ttcttggcga acaggatatt tactattgat
     1441 taatagcaga tttccttgat aaacctgttc ttctgtaatt gttttctctt gggtattttc
     1501 agaagtccca ctattttcta aatgttcttt gggattttga tcataatttt gaaattcgac
     1561 tttttcctga gaaaacagtg cttcattaac gtagtcataa cctaagtata ttaagaataa
     1621 caataacaat aaaaaaaaca acttcttcat tttcag
//
LOCUS       DACCVZ010000192         1529 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.197, whole genome shotgun sequence.
ACCESSION   DACCVZ010000192 DACCVZ010000000
VERSION     DACCVZ010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.197"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(52..1505)
                     /locus_tag="IVW63_002942"
                     /pseudo
     CDS             complement(52..1505)
                     /locus_tag="IVW63_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724155.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
BASE COUNT          500 a          324 c          285 g          420 t
ORIGIN      
        1 aaaaaacagg aactgctgca aataagcaat tcctgttttt atgttcattg attaatgaat
       61 agagcccatt agttttttga ttggttcttt cacagtaaat agcaagatac caccgacgat
      121 tgctactgca ccgataatac cgaagtaagc agattctgtt cccggtgtgt agaagcgtgc
      181 aatttgtgca ttgattgctt gtgaagaagc atcagctaag aaccaaatag cgattgtttg
      241 tgattcaaat gctcgtggtg ctaattttgt tgtcacagac aaaccaactg gtgaaagaca
      301 caattcagca ataaccacga tgaagaaact tcccaacaac cacaatggac ttacttttcc
      361 acttgtacca taaagcatac ccggcaacat caatagcaag tacgataatc ctgcaaataa
      421 aagtccaaga gagaatttca ctactgtaga tggttgacgt tcaccaagtt tcgtccacat
      481 cgttacgaat actggtgtca gaataaagat gaaaattgga ttcaatgatt gataccagct
      541 tgcttggatc gttacaccaa atagcgtaga ttgtgtacgt tcactagcaa ataaagctaa
      601 gatagatgaa ccttgttctt gtaatgacca gaaaatgatt gctgcaagga ataatgggat
      661 ataagcccat actcttggtt tttcttcagc agttacatct tttgaagtca gcattttgat
      721 aaagtaatac aacggtaaga taatccccaa tacactgatt gtattgacaa aaaagtcaat
      781 tgtcagatga ccagttagtt gtgccccgcc gaatactgca gcgataacaa caagtgcgat
      841 gatcaagtta cggatgaatc ctttacgttc ttcagttgtc aaaggattcg gcggtgttgt
      901 acccactccg tctaatgtct tgcgtccttg gatgatgtat tgtaataatc caaagaacat
      961 cccaatagca gctaaagaga accctaaatg atagttatat tcttgaccga ttgtactgct
     1021 aataatgccc ctaagttgac acccatgtaa aaaatcgaaa atcctgcatc tcttcgcaag
     1081 tcagtctttg aataaagatg tccgaccatg ccagaaacat ttggtttcaa aaaggcggtt
     1141 ccgataataa tcaatgccat cgaaacaaac aatgtactta caccaaatgg taaagccaag
     1201 acgatgtggc caagcataat gaaaactcca ccgaagaata cagtgcgttt tgctcctaac
     1261 actcggtcag atacccatcc gccgacgata ctagacatgt agatcaaaga tccgtagatc
     1321 gacatgatag ctaatgctgt tgctcgtggt aatccaagtc ccccgttggc aactgtatcg
     1381 tacatataat agataagtaa tgcacgcata ccgtaataac taaatcgttc ccacatctca
     1441 gtgaagaaca aagttgacaa tcccttcggc tgcccgaaga agcccttgtc ttgctgtttt
     1501 tccataatct ataccccaat tctttaaat
//
LOCUS       DACCVZ010000193         1520 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.198, whole genome shotgun sequence.
ACCESSION   DACCVZ010000193 DACCVZ010000000
VERSION     DACCVZ010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.198"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            905..1117
                     /locus_tag="IVW63_002943"
     CDS             905..1117
                     /locus_tag="IVW63_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005814946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7861153.1"
                     /translation="MKNRLEELRKQRGIKQEDLASALEVSRQTIGSLENGRYNPSIIL
                     AFKIARYFQMSIEEIFIYEEESEDEK"
     gene            1107..1502
                     /locus_tag="IVW63_002944"
     CDS             1107..1502
                     /locus_tag="IVW63_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008688205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861154.1"
                     /translation="MKNKGQIWYIGYIVSLFLIVTILVTDFPKMVDIGLAILFSAVFG
                     VSHVQILHDKMIKNDADYKINVMDERNIIIKEKAGNITNMFNTILLGVATVIFICLDY
                     IIPAIIVGSIIAIQPIILIIISSVLEKKM"
BASE COUNT          531 a          225 c          253 g          511 t
ORIGIN      
        1 cgtattaatt tatctagatc tattaataat actgatccct aataggtgta aaacagttat
       61 aagaaatgag tactctagta tttgtgttac ccgaataatt acttgattat attggtttcc
      121 catataattg aaggctgtcc taatttttac ctactatatg atcataattg attaactctt
      181 atatatttcc gaaaattatc ttgaagattt ctattggtat ggagaatatc catttcattg
      241 ccaataagga tataaattct caaaataaca atcgatgtct gtattaaaca agcctagaat
      301 ggtaaatctg attcgccaaa accattggat tgtatcgatt tgctttacgc gaacgccacc
      361 tacccatttt ataaaaataa aatgggcaaa agatctttct ttttgtcata caaaaagaag
      421 aaaaaaaaga gacgattttc ttcttccaaa atcgtccctc ttttttctaa aaccatggat
      481 gaacgaacaa aaaatctctc gtattttgtt tgttcatcca ctaaaaatat gcgaacagta
      541 tggtttcatt caatcctgtt cttacaagtc aaaagcatcg aatcgtcctt ggacgattca
      601 acaaaaaaag tagtcgtttt tggatgacta ctaagttcta aacattcatt acccaaaatc
      661 aatttggtct aacatcgttt ctcgactggc ttgatctaat cggctcttga cagggctttt
      721 tcttttctgt tgatagcaga taagaggaaa taagaataag tgtgttcatg tgtcataaaa
      781 acagtaacta aaacattaaa atcaaaattt atacggaaag cttccttgac attttgtgct
      841 cgcaggagta ttataaaagc acgaaaggaa agtaaacttt ccatttttta gaaaggagca
      901 tgttgtgaaa aatcgtttgg aagaattacg aaaacaaaga ggaattaaac aagaagattt
      961 agcttctgct cttgaagtat ctcgtcaaac aataggttct ttagaaaatg gacgttataa
     1021 tccctctatt atattggcat ttaaaattgc aaggtacttt caaatgagca ttgaagaaat
     1081 ttttatctat gaggaggaaa gtgaagatga aaaataaggg tcagatttgg tatatcggtt
     1141 atattgtttc gttgtttttg attgtgacaa ttttggttac agattttcct aaaatggtag
     1201 atattggact tgctatttta ttcagtgccg tttttggcgt ttctcatgtt caaattttgc
     1261 atgataaaat gattaaaaat gatgcagact acaaaatcaa tgttatggac gaacggaata
     1321 tcataatcaa agaaaaagcg ggaaatataa caaatatgtt taacacaata ctgttagggg
     1381 tggcaacagt tatatttatt tgtttagact acatcattcc agctattatt gtcggaagta
     1441 tcattgcaat ccagccgatt attttaatca ttatcagtag tgtgcttgag aaaaaaatgt
     1501 agaaataaag gttcatacaa
//
LOCUS       DACCVZ010000194         1495 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.199, whole genome shotgun sequence.
ACCESSION   DACCVZ010000194 DACCVZ010000000
VERSION     DACCVZ010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.199"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..613)
                     /locus_tag="IVW63_002945"
     CDS             complement(<1..613)
                     /locus_tag="IVW63_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP7861155.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFL"
     gene            901..>1495
                     /locus_tag="IVW63_002946"
     CDS             901..>1495
                     /locus_tag="IVW63_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP7861156.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKK"
BASE COUNT          525 a          215 c          283 g          472 t
ORIGIN      
        1 gcaggaagta ttgagttagt ttgtaaagtc tgcgatcttc aaggatcgta aatagctgat
       61 gggttgtccc atcaacacaa ataaaactca tggaaccaga aacagacttc attgatttga
      121 actcatccat acacaacacc gtcggaagga agttcatacg tggctggtaa tgcttcgttg
      181 cttcacgcaa gatccgtgtc accgtcccat ccgagacgaa gtacttctta gcgattagtt
      241 tacgtgattg attttcgtac agttctatga gaatcgcctg cttcagttcc tttgttagtt
      301 gatgatgttc atcaactaag tccgttttcg cagaaaaggt ctgcccacaa tcatagcata
      361 gaaaacgggt acgttttaat tctaaaatag tcaacttttc tttgactttc aatatctgag
      421 tacgtgtcgt ataggaaccg ttgcggataa tacgaatcga tccacagtgt tcacaatggg
      481 aaggtgagtc atccaatctc cctttaataa actgcgcttg aacgccttta tattcttttt
      541 caatcagcca ttcttcatca aaaaataaat gtttatctgt taatccgagt aattttctag
      601 tatgattatc catagagcga ctcctttggt agggtgatgt tttggtcgac taaattttac
      661 caaaagtgag tctctttttg agttgaaacg aagaaaaagt gttagtagaa aatcgccttc
      721 gattttccaa caacacaaaa tattatagaa ccctttattc taaaggattt caaggtgtct
      781 gtttgcattt attagaaaaa agaaaaagta ttggcaacag aaggtgtcac caacactaga
      841 tattatagag ccataatatg ctgtataata tctagtgtat aggcttaagt ggaggtatat
      901 atgaaaatat taactgttga agatgataat atgataagag agggaataag tgaatatctt
      961 tcagaatttg gatatactgt tattcaagct aaagatggaa gagaagcctt gtcaaaattt
     1021 aatagcgata taaatttggt tatcttagac attcagatac cttttataaa tggtttagaa
     1081 gtgttgaaag aaattagaaa gaaaagcaat ttaccaattc taatcttgac tgcatttagt
     1141 gatgaagaat ataaaattga tgcatttact aatttagtag acggatatgt agaaaagcca
     1201 ttttcattgc cggtcttaaa agctagaata gattctttaa ttaagaagaa ttatggacat
     1261 ttagagaagt ttgaatataa ggatctatcg gttaatttta atagctatac agctaaaata
     1321 aatggtgaag aaatagatgt aaatgcaaaa gaactagaag tattaaaatg tttattggat
     1381 aataatggac aagtgttaac aagaatgcaa attattgatt atgtatggaa agatagcgaa
     1441 gaaactcctt atgatcgagt aatagatgta tatataaaag aacttagaaa aaaat
//
LOCUS       DACCVZ010000195         1467 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.200, whole genome shotgun sequence.
ACCESSION   DACCVZ010000195 DACCVZ010000000
VERSION     DACCVZ010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.200"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(315..398)
                     /locus_tag="IVW63_002947"
     tRNA            complement(315..398)
                     /locus_tag="IVW63_002947"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(362..364),aa:Leu,seq:cag)
     gene            926..1426
                     /locus_tag="IVW63_002948"
     CDS             926..1426
                     /locus_tag="IVW63_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7861157.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
BASE COUNT          466 a          252 c          236 g          513 t
ORIGIN      
        1 tttgaacgtt taaacacatt caaaatatag taagaggtca tgcgatttat tctttcgcat
       61 gacctctttt tgagtttaag tttagtcttt attccttaac tatcgtttgc cagtatttct
      121 tgtatcagaa tctataaatc tactatttga atcaatctat taggttttaa actgtcccac
      181 cttcacacaa attttttttg atttatttga atctggttcc gttgtttaaa atttttccta
      241 tattctttta gataatatgt tattttcttt ctcatcgctc caggtgtacc ttctctttat
      301 aaaaaaacaa attatgcggc taagaagact cgaacttcca cgaggtcacc ctcactagcg
      361 cctgaagcta gcgcgtctgc caattccgcc atagccgcat cacatctttt agtttaggat
      421 tacatgtgtt ttttgtcaag aacatatttt tgttcttttt catttctgta cgccctccct
      481 tatgccatct acacaaataa ttcatccgag caactccatc atctattgag ggttggtgaa
      541 aaaatctgtt ttatccatat gatcgatttc aatgttaaac gaacgactct gggattagta
      601 actattttat ttttttcttc atttcttttt tcctcttttt ctcgattcag ctatcttctt
      661 tcatttggat attgattatt tcttctgttg attactatcc ttctggaatt ctagacgctg
      721 aagtaattca cgttttcttt cttctagaga tcataagtaa cgaatgaacg aacttcaaat
      781 aattttttta ttgtaattca tatttgtatt gttcgatgat tcttaatacg atatgacaca
      841 ataaataaaa ataggcatgg ctatttacaa caatagtgct atagtagaaa acaaatgaat
      901 aaggttactt aaagaggtga atacgatgaa actgatcaaa ctatgggaag cagatttaaa
      961 gaaagcttat cagctacaaa ctagctttgg accaaatgag agtggattta tcaacaatgc
     1021 ttatggctat acatttgctg aatttttaga ttatgtaaaa aaatgcgaaa aaacgtcttt
     1081 aggaatcgat cttcctgaga gttacgttcc cgcaaccgtc tttattttag aaagtgatga
     1141 acatgagtat gtaggaattt ttaatttgcg ccataaactg aacgaaacat taagaaacgg
     1201 cgctggccat attggttacg gcatctcccc taattatcgt aaaaaaggat atgccacaca
     1261 aggattagca ttagtactac aagaggcaaa aaaaatcggc attgatgagg cacttttgtc
     1321 tgtaaataaa aaaaatcttg gcagtcttaa agcacaacaa aaaaatgggg ctgcgattta
     1381 tcgtgaagat gagaaagaat actatacgaa aatcaaactg atgtaaaaaa gaaggattcc
     1441 aaaaggaaag ggatttgaat gtccttt
//
LOCUS       DACCVZ010000196         1407 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.201, whole genome shotgun sequence.
ACCESSION   DACCVZ010000196 DACCVZ010000000
VERSION     DACCVZ010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.201"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(48..419)
                     /locus_tag="IVW63_002949"
     CDS             complement(48..419)
                     /locus_tag="IVW63_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861158.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(421..822)
                     /locus_tag="IVW63_002950"
     CDS             complement(421..822)
                     /locus_tag="IVW63_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861159.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            complement(836..1243)
                     /locus_tag="IVW63_002951"
     CDS             complement(836..1243)
                     /locus_tag="IVW63_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861160.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
BASE COUNT          453 a          241 c          176 g          537 t
ORIGIN      
        1 tacaaagatt aaataaaaaa ataacaaaca aactcgcttg aaattcatta ggtgagtttg
       61 tttattattt tttctgcttc tcgattcatc agcgccatat ctgttttcgt aatggtttca
      121 ttaggaatat agtcagcaca ttttcttttc tctaacattc tatacccact attatgtatt
      181 cctaaggtat tcaattcctt aactgttgaa aacaaattcc aaacggtttg gtggcttcct
      241 tttccgctac ttccattata aataatatca taattttctt tcaaatactc atcagatttt
      301 ttaaaagcac tgtagtatgc tcttgaaaca gcagttcttc tataagattc tttagaatta
      361 tatttatcat ctgattcaat ttgtttggaa atagataaat attcattaaa gtcaaacatt
      421 ttattccccc aaagttgcta ctacagattt ccccatatat ttatagtcag ataatacatt
      481 atcgagagta tccaaaacat cgtaatctga ggaaaacaat tcagatgttg ttttgataac
      541 aaagaaatac aagtttaaat cttcatcata ttttatattg atttcagctt ttctttttaa
      601 aaccgtattt atcacatcaa aaattttgcc atcattactt gaaattgtgt taatctcatt
      661 ttttgtagta attacaagtt gattatcatt tttagttttc ggagtagaac ttgcatccac
      721 aacaactgga gatgctagaa ttaccgatgc gcaagcaaaa atcgcagcaa aatttattaa
      781 gctaccactc cgatgtgtat ttgatggtac tatatcaagc atccgtatcg tctccttaat
      841 ttttttccac tggtttgttg accttgatat caaagatttg ccttccaatc tcagttccat
      901 taaatttaac aacagcataa tgctctcctg cttcttcaac caagacattt ctggcgttta
      961 tattaaagtt tatatcgtta acttgaggag gcaagcttac cgatacttca cccgtagaaa
     1021 aaatttgttt ttcattcttg tttaaaactt caatttctac tatttttatc ttttctgtat
     1081 cctctatctc agacaccaca gctgttacag aaaatgataa agcagtagga attaaaggcg
     1141 cattaataga aagagctgga ttaattactt tattaataac attagtgcca aattgctgac
     1201 tttctacatc ttctgaaatt attaattgta ctctataaga cattgatttc tcctaatttt
     1261 tacatttatt taataaattt atgtttcact tttgctagtc aatttagttt aacaatagta
     1321 acaaagcttt gtcaacggaa atattagcta attttgtaag catatttata agtatatttg
     1381 taagcatatc tgacatttaa tcagtag
//
LOCUS       DACCVZ010000197         1374 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.202, whole genome shotgun sequence.
ACCESSION   DACCVZ010000197 DACCVZ010000000
VERSION     DACCVZ010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.202"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            63..806
                     /locus_tag="IVW63_002952"
     CDS             63..806
                     /locus_tag="IVW63_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861161.1"
                     /translation="MVVSKLPRNEDYLTNYDGYVVTTEHFDLANPVTKVDDIPDYEMY
                     SQTIDSLNKRFGNRVLKGIKIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDD
                     EVKDMDPAIVIPQYFAQLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPIL
                     DQVIKNKLAFELNAKSAYLYDNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFD
                     DLFALLKANGVTELAIYQKGKRIMVPLPV"
     gene            complement(843..1340)
                     /locus_tag="IVW63_002953"
     CDS             complement(843..1340)
                     /locus_tag="IVW63_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP7861162.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT          433 a          239 c          231 g          471 t
ORIGIN      
        1 tagttaattt tttcctagag gaaaatgtct aaacatgttg gtaaatcaac aaaaaaacgc
       61 atatagtagt ctcaaaactc ccaagaaatg aggactattt aacaaactac gatggttacg
      121 tcgtgacaac tgaacatttt gacttagcca atcctgttac taaagtcgat gatatccccg
      181 attatgaaat gtacagtcaa acaatcgata gcttaaataa gcgttttggc aatcgtgttt
      241 taaaaggcat caaaatcggt tacatcgctt ctgaaaagga tcggatcatc gactatttag
      301 ccgataaaga ttacgattta aaattactca gtgtgcatca taatgggcaa tttgattatt
      361 tagatgacga agtcaaagat atggatcctg ctattgtgat tcctcagtat tttgcacaac
      421 tttcagaagc actagttgtt atagaagcag atgtctttgc tcattttgac tatggttttc
      481 gggtatttgg tctatccgtt gctgaattta aacaatatga agcgcagttt ttaccgattc
      541 tagatcaagt aatcaaaaat aaattggcat tcgaattaaa tgctaagagc gcttacttgt
      601 atgacaattt agcgttatat gaatatgtca tcgatttata tctttcacgt ggtggtacct
      661 tgtttagtgt tggatcagat gggcattacc ttgaacattt ccgtttccat ttcgatgatc
      721 tttttgctct gttaaaagca aatggtgtga cggaattagc gatttatcaa aaaggaaagc
      781 gaattatggt tccattacca gtctaaaaaa acgtcctcag catcaaaagt gaggacgttt
      841 ttttagattt ctttttctaa aatcggacaa atacgatctt gttttcctaa aggaaaatgt
      901 ttgatcccga tttttttaaa tccatgacgt tcataaaaac gaatacctgc atgatttttt
      961 tcataaacag tcaaacgtaa ataacgtttt tgtttcgttt tagcataacg attcgcttca
     1021 tcgagtaacc gttgccctaa ccctttgttt tgataatctt tgagcagata gagccgttga
     1081 atctctatag catctttttc atcattgact ttcatataac caatgagtat ttgatgatcc
     1141 ttaataccaa taaatttact ggttgactgt gccaattcta ctgccaatat ttcagttgtc
     1201 aattgtgtct gtaaatatcc ttgcatatca agtggatctg cgccatcgat aaacgattca
     1261 taaaaactga caacacttac aacttgtaaa gcatctagat catcataatc taaatacgct
     1321 agtgtgattt gattgttcat ctaactcctc cttttgacat agtatactat aaat
//
LOCUS       DACCVZ010000198         1352 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.203, whole genome shotgun sequence.
ACCESSION   DACCVZ010000198 DACCVZ010000000
VERSION     DACCVZ010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.203"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            11..1350
                     /locus_tag="IVW63_002954"
     CDS             join(11..452,452..1350)
                     /locus_tag="IVW63_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HAP7861163.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          565 a          175 c          235 g          377 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag agaacgcata tttaaaaaag ttagaaacct tgattcaaga
      481 acaagatttg agcaagaaga aatcaaggtt aaaacaatcc ttcagctcaa aaaagaattt
      541 aaattgaatc tattactttc aattgcacaa ttagcgaagt caacttatta ttactgggta
      601 aaaaaattag ataagccaga taaatatagc aagataaagc aagaaattac agcgattgta
      661 aaagaatcaa gaaactctta tggttatcgt agagtcactt tagcgttaaa gatgaaagga
      721 tatacaatca atcataaaac agttagaaaa ttaatgtccc aaatgggact tacctgtcaa
      781 atccgaataa agcgatataa atcttataaa ggaacagtag gaaaaattgc caagaatgtg
      841 ttaaaacgaa atttttcagt agatacaccc aataaaaaat gggtgacaga cgtcactgaa
      901 ttcaagataa aaggaagaaa aatctatcta tctcctatac ttgatttatt taacggagaa
      961 ataattagtt atagtatatc aactagtcca acatataaac tgattgaaga aatgcttcaa
     1021 caagcaatta aaaaaaaggg aactgagggt tcactgattc tacattcaga tcaaggatgg
     1081 cagtatcaga tgccacaata tcaaaaaaaa ttaaaagaga ataacattat tcaaagcatg
     1141 tctagaaaag gaaattgctt agataattct gtaatagaaa atttttttgg tgtgcttaaa
     1201 tcagagtttt tttatcgaga aaaattccga tcaattgaga tatttcaaag taaattaaat
     1261 gagtatatta ggtggtataa taacaaaagg ataaaactaa agttaaatgg actatctcca
     1321 gtagaatatc ggaaacagtc cattaaatag tt
//
LOCUS       DACCVZ010000199         1343 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.204, whole genome shotgun sequence.
ACCESSION   DACCVZ010000199 DACCVZ010000000
VERSION     DACCVZ010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.204"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            48..1343
                     /locus_tag="IVW63_002955"
     CDS             48..1343
                     /locus_tag="IVW63_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP7861164.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          421 a          266 c          256 g          400 t
ORIGIN      
        1 aaatccttta gaattaattt ggctaccaat tcataggagg attcaagatg tctcatactc
       61 agcttatcaa agatacccta aatattctag acctaaatat ctatttcgag gaaaattgtt
      121 taactaaaga aaaatacaaa gggcaaattt gcttgattta caaaggaact cttctgtaca
      181 agccagaaga gtgttcccat tgtctttgtg tcgtcccctc taggatcatt cgttggggga
      241 cgacaaccgt tcggttgtta ctgaatgatg tgtctgagta tcgcacttat ctggagctga
      301 agaaacaacg atttaaatgt aagtcttgcc aaagaacatt cgtagcggat acctctgttg
      361 ctgaaaaaca ctgtttcatt agtcaaaaag ttcgttggtc tgtcattgct cgcttaaaag
      421 agaatacttc catgacggaa atcgctcgtc agaaaaatat ttccacttct tcggtctatc
      481 gtgtcatgaa gcgattctac cgcccattga atcctttcaa acagactttg ccaaaggtct
      541 tatgctttga tgaattcaaa tcggttcgaa gtgttgccag tgcaatgagt tttatcatga
      601 tggacggaca aagccatgca ttattggata ttgtcgaaaa tcgacgcttg ccttatttag
      661 aacgctattt ttctcggttt tcattagcga ctcgtgaagc cgttcaattg attgttattg
      721 atatgtatgc gccttatgtt tcgttggtga aaaagctttt cccgaatgct cagttgatca
      781 tcgatcgttt ccacatcgtc caacatattg gcagaacttt cttgaatcat cgagtgaaag
      841 aaaccacggt acgacttaaa ggaaattccc actctcaacg agggttaggg aaaaaattga
      901 agcgctattg gaaactccta caaaaagaag aagcaaagtt aaactatgaa aaacgggttt
      961 ggcgtgccag ttttaaagat tatttgactg aaagtgagat tgccgatcga ctgttagctg
     1021 cttgtcccaa cttacgccaa ggctatcagt tataccaaga cattctttat gcggtaaaga
     1081 aaagagatca gtcactattt gaggattgtt taactagaga cattagcggt ctgccagaaa
     1141 cctatacaac cactttacga acgtttaaaa agtttctgcc acagatccaa aatgcgcttc
     1201 actacagcta ttcaaacgga ccattggaat gcttaaacaa ccacatcaaa gtattaaaac
     1261 gcaatgcgta cggctttcgc aacttttaca atttcaaact acgaattatg attcgtcatg
     1321 gcaaaacatt tttaaccaaa taa
//
LOCUS       DACCVZ010000200         1334 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.205, whole genome shotgun sequence.
ACCESSION   DACCVZ010000200 DACCVZ010000000
VERSION     DACCVZ010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.205"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            86..1165
                     /locus_tag="IVW63_002956"
     CDS             86..1165
                     /locus_tag="IVW63_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006908283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP7861165.1"
                     /translation="MTQNHDNTVSRKGKHLTYSERCQIAILKKENYSNRQVADVLGCV
                     PQTINNEIKRGTVTQLNRQNQNGKVYDYYHDVYDADAGQAAYEKNRLNCGRRPLWADT
                     DAFIEWADDMMLLEKWSPDVVVGFARKHELFDPAIIPGTTTLYQWIDRGIMKTKNMDL
                     LEKLSRKPKSSRHGNRPNKRVLGKSIEERPEAVGTRKTFGHWEVDTVVGNKTKSDAVL
                     LTLVERQTRFEVILKLAGKDAESVNQAVRQLRERAGAYFGQLFKTVTSDNGSEFAGLH
                     DALQDVANIYFSHPYASWERGTSENQHKLIRRFIPKGSPIGNVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFRQERLTA"
BASE COUNT          359 a          357 c          369 g          249 t
ORIGIN      
        1 agccatttgg aaataaaaaa acgccacgtg aattccatgt tatattgaag ttaccacaac
       61 tctcaataga caaggatgaa ttcacatgac gcaaaaccat gataacacag tttcacgcaa
      121 gggaaaacac ctaacctact cagaacgttg ccaaatcgcc atcctgaaaa aggaaaacta
      181 ttccaaccgt caggttgcgg atgtcctggg ctgcgtgccg cagaccataa acaacgaaat
      241 caaacgcggg accgttactc agcttaaccg ccagaatcag aacgggaagg tctacgacta
      301 ttatcatgac gtctacgacg ccgatgccgg gcaggcggcc tacgagaaga accgcttgaa
      361 ctgcggcaga cggcccttat gggccgacac ggacgccttc attgaatggg cggacgacat
      421 gatgctgttg gaaaaatggt ccccggacgt ggtggtgggc tttgccagaa aacacgaatt
      481 gttcgacccg gccattatcc ctgggaccac caccctctat cagtggatcg accgtggcat
      541 catgaaaacg aagaatatgg acctgctaga aaaactgtcc cgcaaaccga aatcgtcccg
      601 tcatggcaac cgcccgaata aacgggtgct agggaaatcc attgaagagc gcccggaggc
      661 ggttggtacc cggaaaacct tcggccattg ggaagtcgac acggtcgtag gaaacaagac
      721 caagtcggat gccgtgctgc tgacgttggt ggaacggcag acacgcttcg aggtcattct
      781 gaagctggcc gggaaggatg ccgaatcggt caaccaagcg gtccgacagc tgagagaacg
      841 ggctggtgcg tacttcggcc agctgttcaa gacggttacc tcggacaacg gctcggagtt
      901 cgcgggactg cacgatgcct tgcaggatgt ggcaaacatc tacttcagcc acccctatgc
      961 ttcctgggag cgcgggacga gcgaaaacca acacaagctg attcgccgtt tcatccccaa
     1021 gggcagccca atcggcaacg tgagcgaaaa ccaaatcttg cggattcagc gttggatgaa
     1081 cgattacccg cgaaagattt tgggctatgc aacgccgcat gacacgttcg tccaggcatt
     1141 taggcaggaa cggttgacgg cttgacacgt gggcccttga caacgagcct ccctcggcat
     1201 ggcttgtgtc tggaaagctg gccggggcca gccagtcggg agactaccat gcctcagctc
     1261 attgtcaagg gcccactcga ttagaaaaat tagacggttg gtggtaacga gcaaccgggt
     1321 caccatgggt ggct
//
LOCUS       DACCVZ010000201         1313 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.206, whole genome shotgun sequence.
ACCESSION   DACCVZ010000201 DACCVZ010000000
VERSION     DACCVZ010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.206"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            200..742
                     /locus_tag="IVW63_002957"
     CDS             200..742
                     /locus_tag="IVW63_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861166.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..1272
                     /locus_tag="IVW63_002958"
     CDS             898..1272
                     /locus_tag="IVW63_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HAP7861167.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDVEWQHFF"
BASE COUNT          532 a          148 c          256 g          377 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccagatgt ggaatggcaa
     1261 cacttttttt gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gct
//
LOCUS       DACCVZ010000202         1294 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.207, whole genome shotgun sequence.
ACCESSION   DACCVZ010000202 DACCVZ010000000
VERSION     DACCVZ010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.207"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..1244
                     /locus_tag="IVW63_002959"
     CDS             <1..1244
                     /locus_tag="IVW63_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAP7861168.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT          423 a          233 c          277 g          361 t
ORIGIN      
        1 ctataacaga gaaagaacat ctccttcctt tggaagaaca attttgtgaa cattgcggtt
       61 cacagatgaa agatatcgga cggacaaaag tacgagaaga aattcgtttc catcaggcta
      121 tgttggattg tctcacccat tatcaacata cctattgttg taaaagctgc gaaaaagaag
      181 gactttcttc ttttaaaaaa gcgatcgttc ctaaaccttt gatttctaat agcttaggtt
      241 ccaatagttt agtggcggaa acgatccgga tgaaatttgg tcagaaagtt cctgcctatc
      301 ggcaagagaa ctattggaaa caaacacatg ggttggatat ttcgagagat aatatcacca
      361 attggcatat taaagcagtg caaaacgcgt tagacccttt aggagaacga ttaagagtct
      421 atcttaatca agaagagatt ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg
      481 ccaaaacaga tacctattac tggcagtttt gtacaggaaa agacagtcag catcccatcg
      541 tttattatca ccacgacgaa agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt
      601 ttacagggta tttacactgt gacggctata gcgggtataa tgccgtggaa agtgtacgac
      661 ttgtctattg tttcgcgcat gttcggcgga aatttttcga agcaattcca aaaggaaaga
      721 aaaacacgga tattcccgca gctcaagcag tcaaacaatt ggataaatgg tttgtcctag
      781 aaaagaaatg gaaagacttt tctcctgaga agcgattaag ctgtcggcaa caagaactgc
      841 gtccattatt tattgctttt tatgagtgga tggcaacgat agatcctgtt gcaaaatcca
      901 agttggatgc agccgttcaa tatgcgtgta aactacgaag tggttttgaa cctatttttg
      961 aagatggtcg tttagaactc acaaataatc gtgcggagcg aaatatcaaa gagctggtga
     1021 taggacggaa aaattggttg cattccacaa gtcttgaagg agcacgaact tcaggaatca
     1081 ttctgagtgt atataaaaca gcagaactta acggattgaa tcctgtaaag tatctagagt
     1141 ttctatttga taagatacca aatcttcccg tactttcagc agaaacttta gatcaactgt
     1201 tgccttggaa caaggatgta caacaacatt tttctcgtaa ctaaaaacgc caaacattcc
     1261 cgattctatt ctataggtcg ggttatttga cgta
//
LOCUS       DACCVZ010000203         1279 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.208, whole genome shotgun sequence.
ACCESSION   DACCVZ010000203 DACCVZ010000000
VERSION     DACCVZ010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.208"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            62..1150
                     /locus_tag="IVW63_002960"
     CDS             62..1150
                     /locus_tag="IVW63_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861169.1"
                     /translation="MYSKNWKKKLVMGVMVGSIFVFAGCSASTDKSKTATSETKTAEV
                     VKSKMKQIEKNVEKILAEKDKDTKLSEYKKFVTESSAYSKSDKTEKKITNTYTESIKK
                     IKTNFKEQDDKDLKENTLDNLEEATENDLSQKVNTLDELKKWVQKESTDVYSQAEVDS
                     LIKKIDDTITTYKNQLEKIKIDNQEATSTETTTESSEVATLQENVSEEPQVVHTNLLN
                     SIEEAAQYLGQKLPQSGGSDAFENGQQNSDGSFTFHYQLHGGPEGITWNIITVNNNGE
                     IIQDDYFKTVPNEATNNNVSTLSQAAISELEAAQLAIAKHNELGRPNATDAGSETTAD
                     GYYFYYMADGTDQMYKYFVSNSGQVQAE"
BASE COUNT          534 a          177 c          224 g          344 t
ORIGIN      
        1 aatataacca cttttatgaa aagatgttat aattaactaa aaaataatag ggagaaaaca
       61 catgtactca aagaattgga aaaaaaagtt agtgatgggt gttatggtag ggtctatttt
      121 tgtttttgca ggttgttcag cttcgacaga caaaagtaaa acggctactt cagaaacaaa
      181 aactgctgaa gtagtaaaaa gtaaaatgaa acaaatagaa aaaaatgtag agaaaatttt
      241 agccgaaaaa gataaagata caaaactgtc ggagtacaaa aaatttgtta ctgaatccag
      301 tgcttactct aagtcagata aaacggagaa aaaaattact aatacctata cagaatctat
      361 taagaagatc aaaacaaatt ttaaagaaca agacgataaa gacttaaaag agaatacact
      421 agataatctt gaagaagcaa ctgaaaatga tctttctcaa aaagtaaata cattagatga
      481 actcaaaaaa tgggtacaaa aagagagtac tgatgtatat agccaagcgg aagtagattc
      541 attaatcaaa aaaattgacg atacaattac cacatataaa aaccaactag agaaaataaa
      601 aattgataat caggaggcta catcaacaga gactacaaca gaaagtagtg aggtagctac
      661 tttacaagaa aatgtttccg aagaaccaca agtggtccac acgaatttat taaattctat
      721 tgaagaagca gctcaatatc tgggacaaaa acttccacaa tcgggcggtt cagatgcatt
      781 tgaaaatggg caacaaaatt ctgatggctc gtttactttt cattatcaac tacatggagg
      841 tccagaaggt atcacttgga atatcattac agtgaataat aatggtgaga ttatccaaga
      901 tgattatttc aaaactgtac ccaatgaagc aacaaacaat aatgtctcta cacttagtca
      961 agcagctatt tcagagttag aagctgctca acttgcaata gctaaacaca atgagttagg
     1021 tagacctaat gcaactgatg ccggaagcga aactacagca gacggatatt atttttatta
     1081 tatggccgat ggaactgatc agatgtataa atattttgta agtaattctg gtcaagttca
     1141 agcagaataa cattgagtta taatgatatt atcagatgaa ctgtatcata aatttttaac
     1201 gtgaaatgtt tgtaatatca attggagaat ggtatatgga tttactaaaa gataataact
     1261 gttatttttt agtaaattc
//
LOCUS       DACCVZ010000204         1253 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.209, whole genome shotgun sequence.
ACCESSION   DACCVZ010000204 DACCVZ010000000
VERSION     DACCVZ010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.209"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            34..906
                     /locus_tag="IVW63_002961"
     CDS             34..906
                     /locus_tag="IVW63_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP7861170.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT          376 a          230 c          302 g          345 t
ORIGIN      
        1 tgatttcatt ctaaaataaa gggagaaatg tctatgctat acggtgcaat tgaagcaggc
       61 ggcacaaaat ttgtgtgtgc cattggcgat gaagaaatga cgatcaagga aagagtgagc
      121 tttccgacaa cgacacctga ggaaacaatg cctttagtca ttgacttctt caaacaatac
      181 caagcagatt tagcagggat tgggattggc tcatttgggc ctatcgatat ccatcgcgat
      241 tccgccactt atgggtacat tacctcgacc ccgaaattgg catggcaaaa ttttgatttc
      301 atcggtacca tgaaaaaaga atttccgatc ccgatttctt ggacaacaga tgtcaatgcg
      361 gctgcctatg gtgagtatgt cttcggcagt ggcaaaggat tgagcagtgt cgtttactat
      421 acgatcggta cgggtgttgg cggcggtgcc ttacaagaag ggcgctttat cgaagggttt
      481 agtcatccag aaatggggca tatgctcgtc gtccctcatc caaaagatga ctttgctggc
      541 agctgtccat ttcatggcaa ctgtttagaa gggatggccg ctggacccgc catcgaaaac
      601 cgcttaggga aaaaaggaca agaggttgca gaagatgatc cttattggga aatcgaagcc
      661 tcctatattg ctcaatgtgc ctacaataca accttgatgt tttctccaga tgtgatcatt
      721 tttggcggtg gtgtgatgaa acaacgccat atgctgcaaa acgtccacga cgcatttgca
      781 aaattggtca atgggtatgt cgaaacacct gagttaagca aatatatcgt gaccccagca
      841 ttagaagaca acgctggaac gctcggttgt ttggcattgg ctcgagaagc ggtcttacat
      901 tcataaacga aaaaaggctc ttcgacattt agtgttggta gagaaagata caactgaaaa
      961 tttagtcata accagttagg cagagtgctt aactggtttt tgttttactt ggaagatcaa
     1021 gccttgaatg agataaattc ttgctcgaaa gttatggaaa tttcgatagc cgtaggccac
     1081 ttgtattgtg caatagtttt ttacaaaaaa aagggggtgc ggatattttt ttggaccttt
     1141 ttaacaaata ggttctgttg caaagtttta aatctactat cagataaggt agaataatag
     1201 aaaaagatag caggaggaat gacgatgagt cattttaaag gaaagcaatt tca
//
LOCUS       DACCVZ010000205         1244 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.210, whole genome shotgun sequence.
ACCESSION   DACCVZ010000205 DACCVZ010000000
VERSION     DACCVZ010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.210"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            25..381
                     /locus_tag="IVW63_002962"
     CDS             25..381
                     /locus_tag="IVW63_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP7861171.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVDNGRYVITHGFTKKTEKTPITE
                     LKHAKELREEWFTNDD"
     gene            371..637
                     /locus_tag="IVW63_002963"
     CDS             371..637
                     /locus_tag="IVW63_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP7861172.1"
                     /translation="MMIKKLIEEKKKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            796..1074
                     /locus_tag="IVW63_002964"
     CDS             796..1074
                     /locus_tag="IVW63_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861173.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYVNNSSGQSVINKQIVENRVLLQSFKNKISFCIISSF"
     gene            complement(1071..>1244)
                     /locus_tag="IVW63_002965"
     CDS             complement(1071..>1244)
                     /locus_tag="IVW63_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP7861174.1"
                     /translation="HRSIKRRHKLYQSLRTASTTIKGMETIRGIYKKSRKEGTLFGFS
                     VCTEIRILLGIPA"
BASE COUNT          479 a          169 c          247 g          349 t
ORIGIN      
        1 aatcaatata tgatataatt gggtatggaa aaaatatctt ttgaaacatt taaaagaccc
       61 aatggtcatg atgaattttt agaatggttg gaaacattac caaaaaaaga tagtgcgaag
      121 cttttacgta caatagaaga aacagaaaag aatgggatgc tagtagctca acggttgaaa
      181 tgggtgaaaa aattagacac taatttgtac gaattaagaa gtaaggtagg atcaaacatc
      241 caaagagcca tctatttcca tgtggacaat ggaaggtatg tcattactca cggatttact
      301 aaaaaaacgg agaaaacacc aataactgaa ctcaagcatg caaaagaact tagagaggag
      361 tggttcacaa atgatgatta aaaaattgat tgaagaaaag aaaaaagata aagattttgc
      421 agaagcatat gaccgtgaag gaagaaaact cgaaactgcg gttgctcttt atcatgctcg
      481 ggaggaagca gggctaactc aagcggagct tgcacaaaaa gcacatacaa ctcaatctac
      541 tattgctcga attgagagag gggataacgt atctttcgat aaacttgatg atatcgccag
      601 ggcattaggt aaaaagctgg tagtagaatt tgcttaaaag cgagttgaaa atatatctat
      661 aataggctcc taactaatca attagtttag tgggcctttt tttactagat agataaaggt
      721 tgtactatag tgtaaaagac aataaatttt atactaaaat tactttaaag agaactagag
      781 agaaaggtac aataaatgaa aaccataaat cttataaaag tatttatagc atcaccaggt
      841 gatatagcag caaaaaggaa tgaagtagaa gaaaccatat atagatggaa tatagaaaat
      901 acagataata caaaagtgat tttgatgcct atacgatggg aaactaatgc gattcctact
      961 tatgtaaata atagctctgg gcaaagtgtt attaataaac aaattgtaga aaatagggtt
     1021 ctgctgcaaa gttttaaaaa taaaatcagt ttttgtatta tttcttcatt ttaagctgga
     1081 attcccaata atatcctgat ttcagtgcag actgaaaagc cgaagagagt gccttctttt
     1141 cggcttttct tgtagattcc tcgaatggtt tccatccctt taattgtggt ggaagctgta
     1201 cgtagacttt gatacaattt atgtcgacgt tttatcgatc gatg
//
LOCUS       DACCVZ010000206         1231 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.211, whole genome shotgun sequence.
ACCESSION   DACCVZ010000206 DACCVZ010000000
VERSION     DACCVZ010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.211"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>1231
                     /locus_tag="IVW63_002966"
     rRNA            <1..>1231
                     /locus_tag="IVW63_002966"
                     /product="23S ribosomal RNA"
BASE COUNT          323 a          280 c          375 g          253 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc c
//
LOCUS       DACCVZ010000207         1202 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.212, whole genome shotgun sequence.
ACCESSION   DACCVZ010000207 DACCVZ010000000
VERSION     DACCVZ010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.212"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..763
                     /locus_tag="IVW63_002967"
     CDS             <1..763
                     /locus_tag="IVW63_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAP7861175.1"
                     /translation="EKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKIT
                     EEKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKE
                     LYANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLE
                     PMDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSL
                     DEIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            835..>1202
                     /locus_tag="IVW63_002968"
     CDS             835..>1202
                     /locus_tag="IVW63_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP7861176.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYF"
BASE COUNT          528 a          137 c          197 g          340 t
ORIGIN      
        1 ggaaaaaatc ataaaaatat ttgataaaat taataattta ttcaagaatg acaatgctga
       61 attaaggaag ggtcttttag agtttaaact tcaagaacta gaacttcatt actcttattt
      121 agtgaaaatt accgaagaaa aagaacaaca aaaagcaata aaagaacaga tgatagaaga
      181 ggaaaaagtt cgtagagaaa ttgatcgtga aaagaaacgt attgataaag aacaacgtca
      241 attcaattct gaaatttcca aattaatcgc atatatgcaa aaagctaatg cagatgtgga
      301 aaaagaatta tatgcaaata aaattcaaga actggaagaa aaattaaaag aattagaagt
      361 tatacgtgaa aatgtattac aaagagaatt aaatactaga gccggttatg tgtatgtaat
      421 tagtaatatt gggtcttttg gtgaagacat atataaaatt ggtatgacta gaagattaga
      481 acctatggat agaataaaag aattgagtag tgcatcggtt ccatttgaat ttgacgttca
      541 tgcgatgatt ttttcagagg acgctccgtc tttggaaact aaattgcata atcattttag
      601 aaaacaagaa gttaataaaa ttaatcaaag aaaagaattt ttcaaagttt cactagacga
      661 aatagagaaa gttgttttag aaaattataa tggaacagta acatttacaa aattagctaa
      721 agctgaacaa tatagacgat ctttagaatt gtcaaaagat taaatatata aaaagccttc
      781 gggctttttc ttttaacaat taataggaac gtatattcga aaggaataga aataatgtgg
      841 ttagaaaaaa taaatgacaa aaaatttaag tacaccgaac gttatacgga tcccttaact
      901 gaaaaaaaga gaaaagtgtc cgttacttta tctagcaatt cacgccaagc ttggaatcaa
      961 gctaacttac ttttgaatga aaaaatcgca gaaaaaataa aacgaaatga agaattacca
     1021 ctaacttttg gagaattaaa aactaaatgg gatgaaaaat acaagccaac tgtaaaagaa
     1081 agttcctatc gaacaactca ggtttatcta tcattaattt caaaatatat aaaagatgat
     1141 gtacttgtaa aaaacgttaa tagtaatctt atacaagata tgctagatta ctactatttt
     1201 ga
//
LOCUS       DACCVZ010000208         1170 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.213, whole genome shotgun sequence.
ACCESSION   DACCVZ010000208 DACCVZ010000000
VERSION     DACCVZ010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.213"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..195
                     /locus_tag="IVW63_002969"
     CDS             <1..195
                     /locus_tag="IVW63_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP7861177.1"
                     /translation="ELTLKQMIVLFKEYPSLLRRPILIDEKRILIGFNEDEIRSFVPR
                     EIRCVARNLIYLQNNNILNS"
     gene            209..565
                     /locus_tag="IVW63_002970"
     CDS             209..565
                     /locus_tag="IVW63_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HAP7861178.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          428 a          174 c          210 g          358 t
ORIGIN      
        1 gaattaactt taaagcaaat gatcgtctta ttcaaagaat atccttcatt attgagacga
       61 cctattttga ttgatgaaaa aagaatacta atcggattta atgaagatga gatccggtca
      121 tttgtccctc gtgaaattcg atgtgttgcc agaaatctga tctatttaca aaacaataac
      181 atcttaaatt catagggagg gagccttcgt ggaagtgaaa gtctatggat cagcgcactg
      241 tgtaacaagt ctgaaggcga aacaatggtt agaacaccat caattgcctt atcaatttgt
      301 tgacttagaa gaacgcgatt taagtacaga agaagcagaa gaattatgca gttttgaaga
      361 agtgcaagca gaacagctat ttgcgacttg gtctgaggct tttcacaaca ttgcgattga
      421 cctttcctgt gtaggaaaaa aacaactgat ttttttatgc acacaacata ccaatctcct
      481 cagacgtcct ttgattatta tcgatgaagt tctatttatt ggatacaatg agcagttgat
      541 ggaacagctt atcttaaata aatagacttt aactgtttta atcaagtcac tgagcatttc
      601 atacagttgt aacagtcgaa cacttagcat caagcgtgtt atgtgttctt tttttgactt
      661 tatttttcta ctatagagac atgctcaatt tatgtggtca aaattcaaat ctaggtgggg
      721 atatagagtt aaaaatatat tgacatgtgt aaatttacat gatatattca tttctgttgt
      781 tttaagtagc aaagcaataa aatagtattt taaaaaacat ataaaatagt tgttgacatg
      841 ttagaaatga catgataaga taactgagtt gttaaaaaag aaccacttgt gaagcttgat
      901 tctatcgaaa aaaacttcaa aaaagttctt gacaaataac aaatgataag ttatgataaa
      961 tgagttgctg taagatttcg aaaaacgaaa tcaaaaaaac ttttaaaaaa gagttgacaa
     1021 ttacttgtct ctctgatatg atataaaagt tgctacggca gccaaaaacg aatcggggaa
     1081 cactcctgat gaagtagacc tttgaaaact gaacaaagta agacaaacca aatgtgtagg
     1141 gcgtcttgat tcaattcaag acaacaaaca
//
LOCUS       DACCVZ010000209         1165 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.214, whole genome shotgun sequence.
ACCESSION   DACCVZ010000209 DACCVZ010000000
VERSION     DACCVZ010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1165
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.214"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(21..1061)
                     /locus_tag="IVW63_002971"
     CDS             complement(21..1061)
                     /locus_tag="IVW63_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAP7861179.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFIPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAETESGISIIFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SFPKTITKDWLE"
BASE COUNT          326 a          190 c          171 g          478 t
ORIGIN      
        1 atcaatttgt cagtgaaatt tcactctaac cagtctttcg taatagtttt tgggaagctt
       61 tcagaattca aacgtttttc acttgatact ttagcagcta ttggtttttc gataaaccaa
      121 ttttttacat agacaaaaat caggttctgg atattttcaa ctttttcggt ttttaatttt
      181 tgataggctt ttaacagtgt cgtgtataat tcttgttctg cattgacata ataactatcg
      241 agttcttcaa aaattattga aataccactt tctgtttcgg cttttttctt tgcattatga
      301 atagtctgga cagttttttg agcttcactg taacttgaag aaaatgtttt tattaaattt
      361 aatactcgtt cagggataaa cgtagcaatg ctgtcgtttg tcataattgt ctcaaaattg
      421 tctaacaaca attgatcttg taggcggtct ttttcagtgt ctatattgtg tctattagtg
      481 tctaatatat tattattaag ttctggtatg attttcatac cctctgattt atcaacgttt
      541 tggcacggta tgattttcat accctcttga gccccaaggg attcagcgtc tgatttttcg
      601 tcgagggtgg gtatgatttt cataccctct gatttatcaa cgttttccct attctctcta
      661 tcaaattttt cgagtaagta gatatcattt tctgagactt ttaattctgc tagatatagt
      721 ctattaggat tatttttccc taactgtttg ttaaatccca tctgcttttg taataataaa
      781 ccaaaggatt ccaactcttt tttgattgct atcgcttttt gtttttggca gtttaatacg
      841 ctacatagtt catttgtcgt ataagtaaaa taaacattac cttcttcatc gatttgccgt
      901 ttgctgattg cgatctctaa tcttgctttt aaaagcatat aggcaatctt agttgaatct
      961 ttcatttttt tgtattcgtc agaaacaata aagacttttg gaaattgata aaataattcg
     1021 ttgtaaactc tatccgcctt aaaaaaatta aaatcagtca ttgtagatcc tctactttca
     1081 cgttgtttta tttatgtaaa attacctact cttttcgaaa atagcaaaga taaataaaaa
     1141 atgcaaacgc attaaaactg ttttt
//
LOCUS       DACCVZ010000210         1091 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.215, whole genome shotgun sequence.
ACCESSION   DACCVZ010000210 DACCVZ010000000
VERSION     DACCVZ010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.215"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            6..980
                     /locus_tag="IVW63_002972"
     CDS             6..980
                     /locus_tag="IVW63_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAP7861180.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          384 a          135 c          187 g          385 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaaact aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta a
//
LOCUS       DACCVZ010000211         1078 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.216, whole genome shotgun sequence.
ACCESSION   DACCVZ010000211 DACCVZ010000000
VERSION     DACCVZ010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1078
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.216"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..357)
                     /locus_tag="IVW63_002973"
     CDS             complement(<1..357)
                     /locus_tag="IVW63_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP7861181.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQEIKNYQIKNKLICHCSGAISS
                     DIFSNIQDYGAYGYSVH"
     gene            595..>1078
                     /locus_tag="IVW63_002974"
     CDS             595..>1078
                     /locus_tag="IVW63_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP7861182.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     F"
BASE COUNT          397 a          179 c          157 g          345 t
ORIGIN      
        1 atggacagaa tagccataag caccatagtc ctgtatattt gaaaagatat ctgaagatat
       61 tgcaccactg caatggcaga ttaatttgtt tttgatttga taatttttaa tttcttgcca
      121 tacctcctga atttgaccat caggagtcgt aatgaaaata gtatcatttt catctactaa
      181 ttctcttaag tttaaatatt gtttactaga tgtaaaattc gaagctgcta atgacgagtc
      241 ttcgctttta ctataaaatc ctgttacttg tattttatgt tcctggaaat acttcccgaa
      301 tgaacaacct accttgccgg ctccaataaa accaacgttc ataattatca cctccataaa
      361 gaagtgagac tacaagtccc attcttacga tatgagctta aaaataaaaa ttaaatcaaa
      421 tatacagtat gtttttttca aatatcatcc atagttaatt tatcataata tcccatattt
      481 taaaataaaa gatagcgtaa aatattttgt gtaaatagaa atttagggta gaaaaaaaag
      541 tccattctgt aaaattaaag ttaccacaca gaaattttat aggaggactt tctcatgact
      601 aaatttacta tagaaattat gcaaacacta ctcaataaag gggatttaga tgaattattt
      661 caggatcatt tagagcgagc gattaattca cttctacaag cagagctaac tgctttttta
      721 gattacgaaa aatatgatcg aaatggattc aattcaggaa attcccgtaa cgggaattat
      781 tcacgtacat ttaaaacaga atatggcgag ttgaatttaa ctattcctag agatcggaat
      841 ggcgaatttt ctcaacaaac actaccagca tataagcgaa ccaatgattc attagaaacg
      901 accattatcc aattatttca aaaaggcatt actatggctg aaatctccaa attaattgaa
      961 aaaatgtatg gtcaccacta tacgccacaa acaatctcca acatgagtaa attggtggct
     1021 gaagatgttt tagcttttaa agaaagaacg ttagaagcca attattccgt tatattta
//
LOCUS       DACCVZ010000212         1063 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.217, whole genome shotgun sequence.
ACCESSION   DACCVZ010000212 DACCVZ010000000
VERSION     DACCVZ010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.217"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(38..994)
                     /locus_tag="IVW63_002975"
     CDS             complement(38..994)
                     /locus_tag="IVW63_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861183.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          380 t
ORIGIN      
        1 tttagaaaaa gcagtcggac tttctaaaag aagttcacta ttcgatcctg tcgatgattt
       61 cttcaggaaa atcgtctatt tgcttgtcaa ttttgctgtc tttgtatttc tcttcttgga
      121 tagtcaacaa aatctttgta agattccccc agtctactgc tcttggcgga tcgagccaaa
      181 ccactacttg agatgcactt tcttcatata gattattcct attcgtgatt ataacatccg
      241 ggaactcagg ctttcctgcc tctatcactt ccgtgttcag attaatgtac aagcttaaat
      301 ttttcttgat aaattgatta taggcagcac cataagaaaa atcgatgatg atctttactg
      361 gttcagaaat cagttgaatg ggtatgtgat tgatcaataa taataaataa ctgaaaaaaa
      421 gaaaaaattt atcttgaagc aactctttgc gttttgacgt tagatcattt atatactcta
      481 tcaaatagca ataaaatgct ggatagtttt ctctaaaaaa agaaacatca agtggaaatt
      541 catcagcttt attaatagtg taatgcaaaa gtttaaaatg tattttggtt aactctcttc
      601 ggatcaattg gctcgtctct tctcgcaaca gattaaactg attttcaaaa ctttcaatga
      661 atcgttcatt caaccattcg attgtttcat cttcattttt tctcaagtat ttttgatcca
      721 atttatcatg aagataaagc caagagagtg tcttattgat aaaaataacg gatttttctc
      781 ctaatactcc ttttaagtgg taaaatccta tatccgaaaa aaatagcgac tgattgctag
      841 caatatctaa agaatcagct tgttcagcca acaggttgat tgctaaaaag tggaataatt
      901 tctttttttc ataagcagac agaggataat actgttttaa atcttttaac attttttctg
      961 tttttataat tataggtagc gtatacaatt ccacaaaact tatctctgtt gagttaaaaa
     1021 gattatataa aaaaagccga atgtttttag gattccctgt caa
//
LOCUS       DACCVZ010000213         1035 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.218, whole genome shotgun sequence.
ACCESSION   DACCVZ010000213 DACCVZ010000000
VERSION     DACCVZ010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.218"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..>1035)
                     /locus_tag="IVW63_002976"
     rRNA            complement(<1..>1035)
                     /locus_tag="IVW63_002976"
                     /product="16S ribosomal RNA"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DACCVZ010000214         1005 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.219, whole genome shotgun sequence.
ACCESSION   DACCVZ010000214 DACCVZ010000000
VERSION     DACCVZ010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.219"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>1005
                     /locus_tag="IVW63_002977"
     CDS             <1..>1005
                     /locus_tag="IVW63_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP7861184.1"
                     /translation="GKKISMILLNRSGNKRTYLRLKKQRYLCRACKKYFTARTYLVTP
                     FCFISKQIHYKILEELTERQSIKAIGKHCDVSVTTVQRTLSALSSDIRQNLEYLPRCL
                     LFDEFRSLSTWHGKFSFSCMDGETGKLFEILPSRRKKDLVAFFMRFSLKARLGVHYIV
                     TDMNAPYFSLVKECFPNAQVIVDRFHIVQHLNRFFDAVRKRVMKTLDQKDPIQAKQYR
                     QLKSLFKLLLKSEDRLDYNTLTKRRNFNWRLLTETEVVDRLLKISPELKTAYRYYQDL
                     LTAYQEKDPDTFFQLLRAMPGEVPLELHHIKKAFFKYEKGIRLALLKKYSNARLENLH
                     "
BASE COUNT          302 a          209 c          191 g          303 t
ORIGIN      
        1 atggcaagaa gatctctatg attctcctga atcgtagcgg taataaacgg acctatcttc
       61 ggttgaagaa acagcgatac ctctgccgag catgtaaaaa atattttacc gctcggacgt
      121 atctcgttac cccattctgc tttatttcta agcagattca ttacaagatc ttagaagaat
      181 tgacagagcg tcaatctata aaagcaattg gtaaacattg cgatgtttct gtgacaactg
      241 ttcagcggac attgtccgcc ttgtcatcag atatccgtca gaatcttgag tatttacctc
      301 ggtgtctatt attcgatgag tttcgttctc tttctacatg gcacggtaaa ttttcttttt
      361 cttgtatgga cggtgagacc gggaaactgt ttgagatctt acctagccgc cgtaaaaaag
      421 atctcgttgc ttttttcatg cgtttttctc tcaaagcgag gttgggtgta cattacatcg
      481 taacggatat gaacgctcct tatttctcac tagttaaaga gtgttttcca aatgcacaag
      541 tgatcgtcga tcggtttcac attgttcaac atctgaaccg cttcttcgat gcggttcgaa
      601 aacgtgtgat gaaaacactt gatcaaaaag acccaataca agctaaacag tatcgccaat
      661 tgaaatcctt attcaaatta cttttaaaat cagaggatcg tttagattac aatacactaa
      721 cgaaaagacg caatttcaat tggagactat tgactgaaac agaagtagtt gaccgccttc
      781 taaagatttc tcctgaactt aaaacagctt atcgttacta ccaagacctg cttactgcgt
      841 atcaggaaaa agatccagat acttttttcc agctgcttcg agcaatgcct ggagaagttc
      901 cattggaact gcaccatatc aaaaaagcct ttttcaaata cgagaaaggg attcggctgg
      961 cattactgaa gaagtattcg aatgcacgac tggaaaatct ccata
//
LOCUS       DACCVZ010000215         1000 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.220, whole genome shotgun sequence.
ACCESSION   DACCVZ010000215 DACCVZ010000000
VERSION     DACCVZ010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.220"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(82..636)
                     /locus_tag="IVW63_002978"
     CDS             complement(82..636)
                     /locus_tag="IVW63_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP7861185.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADVAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
BASE COUNT          324 a          186 c          107 g          383 t
ORIGIN      
        1 acttccgaaa attcagttat cttcattaat ctcaccttct aagttttcat tatacacaaa
       61 aaatatatcc taatatctca attagcctcc caatttaaaa ccacgtaacg atgcccctat
      121 ttcatcttca gttataccaa tgtacctttt tgtaattgct tgcgagctat gattaaaaat
      181 aaacattaag gtagcaatgt ctctagtttt cttgtagtag tgatacccaa aagtttttct
      241 taatgtatgt gttcctatat catctcttcc taatttttct gctacatctg catatatctg
      301 atagacacga tcccttgtta tatgtcgacc ttgttgccga cttggaaata accaatcatt
      361 ttcttcttta ccttcagtat ataataaaat ctcttctctc aaattatcta taaaaatcgg
      421 ttttcgctta cctgttttat gttcaacaat aataggctta cttttacctc gtatgtctcc
      481 aacttttaat cctataatat ctgacatacg taacccatta ttgattccaa acaaaaataa
      541 aaaactatct ctttctggat tacttgttct tcttagccaa aactgaaaat cttgtatctc
      601 ttcatttgtc cttaacggtt gtacattata gctcactatt gtttcccttc ttaaaaatat
      661 tctgagttca tgattatata tatattttac cataatcatg aacttatata tatactctgt
      721 taaaagtgaa gaaaatcaag gggtttagtt tatgatttta tatcatttca gtaactcaga
      781 atattccgac ttttttgtac aaaaaaatta accttactta tatgaagatt ctaagctctt
      841 atttaaattt tagacgggca gttatccgta gaagttctta gaatagctaa tttacataat
      901 taaattatat gaaatttaag tttgaacaat atactaagaa ctccccttac tataaagtga
      961 aataaattag catatgaata accgtgctac caaacttttc
//
LOCUS       DACCVZ010000216         1000 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.221, whole genome shotgun sequence.
ACCESSION   DACCVZ010000216 DACCVZ010000000
VERSION     DACCVZ010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.221"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            369..1000
                     /locus_tag="IVW63_002979"
                     /pseudo
     CDS             369..1000
                     /locus_tag="IVW63_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DACCVZ010000217          983 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.222, whole genome shotgun sequence.
ACCESSION   DACCVZ010000217 DACCVZ010000000
VERSION     DACCVZ010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.222"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(34..107)
                     /locus_tag="IVW63_002980"
     tRNA            complement(34..107)
                     /locus_tag="IVW63_002980"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(71..73),aa:Ile,seq:cat)
     gene            complement(662..976)
                     /locus_tag="IVW63_002981"
     CDS             complement(662..976)
                     /locus_tag="IVW63_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861186.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          363 a          154 c          154 g          312 t
ORIGIN      
        1 tctaacacag aacgattcaa ttggctacat taatgtaccc tgtaggactc gaacctacga
       61 ccggacggtt atgagccgtc tgctctgacc aactgagcta agggtagtgg ttgttgccac
      121 ataaagccat aaacaatcaa ccagtagaat gcgtggcaac aaacctgtta tcgcatatct
      181 tggagtgtga ctatttatga gtgatagtga agatatgcgt ctccatatat gtatggttga
      241 gacagataaa catgtatgaa aaacgttgtt aaatcaacgt ttttttattt tggtcaagga
      301 gagaaaagta gagaaataca aaattttttg cattgatttt gcattcaaaa aaacattcaa
      361 acatttagaa atccccaata cgtattcagg aaaatctatt ttaaggttta caaaaagaac
      421 ttttgttcgt acactctttt tgaggtgaac ttttatgctg atggaaggaa aaacacaatt
      481 atggtttaag catgttcctt caaataagtt ttttaattat aaactctaga gaaattaatt
      541 catcctaaca taaaataatt gttcactcaa aagtttttct agaacaatta aaacagcagg
      601 cttcacattc gctatacatt tgtaagaagt aataattcct gtactaaaag gcataattgc
      661 tttaattatt ttttgacttc tcttcaaaca caagaagtag ttgtgtaata attgcagaaa
      721 taaggattcc aataatagat ataaaatttg acatggaaac gtctataaca ttaaaagaat
      781 aaagtgttga agaaagtaaa ctgattgaaa taacccctcc gtaaaaaata gtctgtgaat
      841 atacccactt tttttcagaa gacgtacttc gtttggttct aaaacctatc cctgcatttc
      901 tactcttatc aaaaaaccaa atatttagaa gtaataatat tgctattatt aagataaaat
      961 tactgtaaaa atccaaaagc tat
//
LOCUS       DACCVZ010000218          978 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.223, whole genome shotgun sequence.
ACCESSION   DACCVZ010000218 DACCVZ010000000
VERSION     DACCVZ010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..978
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.223"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            82..>978
                     /locus_tag="IVW63_002982"
     CDS             82..>978
                     /locus_tag="IVW63_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HAP7861187.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYE"
BASE COUNT          333 a          182 c          192 g          271 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaa
//
LOCUS       DACCVZ010000219          947 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.225, whole genome shotgun sequence.
ACCESSION   DACCVZ010000219 DACCVZ010000000
VERSION     DACCVZ010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.225"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(1..222)
                     /locus_tag="IVW63_002983"
                     /pseudo
     CDS             complement(1..222)
                     /locus_tag="IVW63_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322179.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(471..671)
                     /locus_tag="IVW63_002984"
     CDS             complement(471..671)
                     /locus_tag="IVW63_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP7861188.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          341 a          150 c          153 g          303 t
ORIGIN      
        1 tcagtcacga tatcaaacaa aaagtataca cccttcttca ttctagtttt cgcagcagga
       61 attttgaaat agttccttat tagaatagta gagattgatt aataagctat cttcgattgc
      121 taaaaagaaa acttctgaat tccatacttt ataaaaatct ttgataaatc tattcgaagg
      181 gtcaaattta aaccataatt gtgtttttcc ttccatcagc ataaaagttc acctcaaaaa
      241 gagtatacga acgaatgttc tttttgtgaa ggcggaattt aatatactga ataatagaaa
      301 acaagtactt gtgccaaatt atgtgccaaa aaaattcgaa ttcaacaaaa tgtaaacaaa
      361 tagaaaacct tctatattaa gatttcctgc aataacaaac acaacagaag acgtgtaata
      421 gttagtcagg aacgtacaaa taacccctgt atcctttgcg gtacaggggg ttattttgta
      481 taagtagaca ttgtagtttc taaactgcta tgtcctaaac gtttcgatac gctaagtata
      541 tttactcctt gataaagtaa aatagatgca tgcgtatgtc ttagtccatc aataaacagt
      601 cgaagagaaa atagggaaaa attgattact aaagaaaaac ttactaggtc gacggtgtag
      661 ttgattttca tacttcaata gattcgaatt aaacgatttc gattggctta taccagtcct
      721 atccaacgaa agatatatcg ttcttaactc tagcggtata acttgaagct ttacgtaaag
      781 ccaatgggaa tgaactggag atgacttttt attattttta gtaatagctg atgggttaat
      841 acttacaact ttccttttca aagtaccata taaaaaaacg gtggggttgt ttagcgaaat
      901 aaaggatcta agccaatagc ttagatcctt tattctatgc tttatat
//
LOCUS       DACCVZ010000220          865 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.226, whole genome shotgun sequence.
ACCESSION   DACCVZ010000220 DACCVZ010000000
VERSION     DACCVZ010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.226"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(46..118)
                     /locus_tag="IVW63_002985"
     tRNA            complement(46..118)
                     /locus_tag="IVW63_002985"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(83..85),aa:His,seq:gtg)
     gene            complement(121..194)
                     /locus_tag="IVW63_002986"
     tRNA            complement(121..194)
                     /locus_tag="IVW63_002986"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(160..162),aa:Trp,seq:cca)
     gene            complement(201..281)
                     /locus_tag="IVW63_002987"
     tRNA            complement(201..281)
                     /locus_tag="IVW63_002987"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(245..247),aa:Tyr,seq:gta)
     gene            complement(283..358)
                     /locus_tag="IVW63_002988"
     tRNA            complement(283..358)
                     /locus_tag="IVW63_002988"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(323..325),aa:Phe,seq:gaa)
     gene            complement(394..466)
                     /locus_tag="IVW63_002989"
     tRNA            complement(394..466)
                     /locus_tag="IVW63_002989"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(431..433),aa:Asp,seq:gtc)
     gene            complement(476..548)
                     /locus_tag="IVW63_002990"
     tRNA            complement(476..548)
                     /locus_tag="IVW63_002990"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(513..515),aa:Val,seq:tac)
     gene            complement(564..635)
                     /locus_tag="IVW63_002991"
     tRNA            complement(564..635)
                     /locus_tag="IVW63_002991"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(600..602),aa:Glu,seq:ttc)
     gene            complement(650..739)
                     /locus_tag="IVW63_002992"
     tRNA            complement(650..739)
                     /locus_tag="IVW63_002992"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(703..705),aa:Ser,seq:gga)
     gene            complement(779..852)
                     /locus_tag="IVW63_002993"
     tRNA            complement(779..852)
                     /locus_tag="IVW63_002993"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(816..818),aa:Asn,seq:gtt)
BASE COUNT          241 a          239 c          196 g          189 t
ORIGIN      
        1 aaagtccctt gccttaccgc ttggctatac cccaagaata aaaagggcga atgatgggaa
       61 tcgaacccac gaatgccgga gccacaatcc ggtgcgttaa ccacttcgcc acattcgcca
      121 tggcaggggc agcaggaatt gaacccacac taacggtttt ggagaccgct gttctacctt
      181 taaactatgc ccctataaaa tggaggagag tggattcgaa ccactgaacc ctaaggaacg
      241 gatttacagt ccgtcgcgtt tagccacttc gctactcctc catggtggcg cgggacagaa
      301 tcgaactgcc gacacacgga gcttcaatcc gttgctctac caactgagct accgcgccat
      361 attttaaaat tattaattga ataacaagaa cgacggttcc gacgggaatc gaacccgcga
      421 tctcctgcgt gacaggcagg catgttaacc cctacaccac ggaaccagtt cattatggag
      481 gttaacggga tcgaaccgct gaccctctgc ttgtaaggca gatgctctcc cagctgagct
      541 aaacctccaa cattcaatta aaatgacccg tacgggattc gaacccgtgt taccgccgtg
      601 aaagggcggt gtcttaaccg cttgaccaac gggccaggta aatttgctac ggagagtaag
      661 ggattcgaac ccttgagaca gtttggcacc atctacatga tttccaatca tgctccttcg
      721 gcctctcgga caactctcca gagtgaaaga agctcaatac tctttctcaa aatgagaact
      781 ccggcagtag gactcgaacc tacgacatca tgattaacag tcatgcgcta ctaccaactg
      841 agctatgccg gaataacatc agcgt
//
LOCUS       DACCVZ010000221          862 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.227, whole genome shotgun sequence.
ACCESSION   DACCVZ010000221 DACCVZ010000000
VERSION     DACCVZ010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.227"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            124..321
                     /locus_tag="IVW63_002994"
     CDS             124..321
                     /locus_tag="IVW63_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAP7861189.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            323..634
                     /locus_tag="IVW63_002995"
     CDS             323..634
                     /locus_tag="IVW63_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP7861190.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            738..>862
                     /locus_tag="IVW63_002996"
     CDS             738..>862
                     /locus_tag="IVW63_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HAP7861191.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
BASE COUNT          342 a           82 c          157 g          281 t
ORIGIN      
        1 ttaaaagtga ttaaattctt attcaggaat tattttgcta cgtttcaaga aggaattgtt
       61 ttttgaaatt taatgaatgt tagaataata gtctaaaaac attaatttag gggtgattag
      121 attatgaaac atttaaaaat tttgtctatt aaagagacac aacttatcta tgggggtacc
      181 actcatagtg gaaaatatta tggaaatgga gtgtattgca ctaaaaataa atgtacggtc
      241 gattgggcca aggcaactac ttgtattgca ggaatgtcta taggtggttt tttaggtgga
      301 gcaattccag ggaagtgcta aaatgaaaaa aaatgctaag caaattgttc atgaattata
      361 taatgatata tctataagta aagatcctaa atattctgat attcttgagg ttttacaaaa
      421 ggtatattta aaattagaaa aacaaaaata tgaattagat cccagtcctt taataaatag
      481 attggtgaat tatctatatt ttactgctta tactaataaa ataagattca ctgaatatca
      541 agaggaatta ataagaaatt tgagtgaaat tggaagaact gctggaataa atggtttata
      601 tcgagcagat tatggagata aatctcaatt ttaatgatac ttataatatt aaatatgtct
      661 caaaattttt tgattagaaa aataggtata ttgaatcagt gacataaaag tatttatagt
      721 ttgtaggggg aatcgtaatg gaagaaaaaa atagactaaa tgctaaacaa tgttcagatc
      781 aagagcttaa aaaaattaaa ggaggtgctg gaacaaaacc tcaaggaaaa ccggcatcaa
      841 atttagtgga atgtgttttt tc
//
LOCUS       DACCVZ010000222          832 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.228, whole genome shotgun sequence.
ACCESSION   DACCVZ010000222 DACCVZ010000000
VERSION     DACCVZ010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..832
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.228"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..693
                     /gene="tnpB"
                     /locus_tag="IVW63_002997"
     CDS             <1..693
                     /gene="tnpB"
                     /locus_tag="IVW63_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAP7861192.1"
                     /translation="ATISRHSSGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILS
                     DGQKIDNNKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEK
                     VMNQRTDFLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYK
                     ADWYGRKIIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINIL
                     TEGLRLHSMGLA"
BASE COUNT          304 a          132 c          154 g          242 t
ORIGIN      
        1 gctacaatat cacgtcattc tagcggtaaa tactatattt ctttgttgtg taaagaagaa
       61 attatcgaat tacctaaaac taattccaca attggtattg acttaggtat tatggacttt
      121 gcgattcttt ctgatggaca aaaaattgat aataataaat tcacgtccaa aatggaaaag
      181 aaactaaagc gtgaacaacg caaattgtct aggcgtgctt tattggctaa aaataaaggt
      241 accaatctat ttgaagctaa aaattatcaa aaacaaaaac gcaaagtagc tagattgcat
      301 gaaaaagtaa tgaatcaacg tactgatttt ctgaataagt tgagtacaga aatgatcaaa
      361 aatcacgata ttatctgtat tgaagactta aacacaaaag gtatgttgcg aaatcataaa
      421 ttagctaaaa gtatttctga tgtttcttgg tcaaagtttg tgactaaatt acaatacaag
      481 gctgactggt atggacgaaa aatcatcaaa gtagataaat ggtttccgtc tagtcagatt
      541 tgttcagagt gcggacataa agatggcaag aaatctcttg aaattcgaga atggacttgt
      601 cctgtttgtc atactcatca tgatcgtgat atcaatgcta gtatcaatat tctgaccgaa
      661 ggtctaagac tacattctat gggattggct tagatccaat catcaagaac cgtaggaact
      721 acggggatag cttggtaaat aagagacacc gctgttagta aagaaatacg ctatcaagta
      781 tgctctattc ccaagaagct cccacttcaa gcgttaagaa ccgtcaggtt ta
//
LOCUS       DACCVZ010000223          829 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.229, whole genome shotgun sequence.
ACCESSION   DACCVZ010000223 DACCVZ010000000
VERSION     DACCVZ010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.229"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(20..625)
                     /locus_tag="IVW63_002998"
     CDS             complement(20..625)
                     /locus_tag="IVW63_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7861193.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT          257 a          146 c          122 g          304 t
ORIGIN      
        1 gaatgaatgt agtatatttc tacaaatcat tcgctttctt tattttataa atagttggtc
       61 gagagatccc gttttctttt gcaatctctg caactggaat gccttgcttt aacatgtcca
      121 ccacggtttt aaaaactaag cgtttttgcg gatctgttga gttaatagaa tactcgattg
      181 gtcgtccctt atatcggccg gctttttgag ccaataatac tccttgccgc tgacgttcac
      241 gaattttctc acgctcgttt tgtgcaatat aacttagcag tgataaaaac atatcgaaca
      301 tagcggtatc caggagttca tttccagtat taaaatctaa aaactgtgca tctaatattt
      361 ttaacgctac ttttttctgt ttcataaaag caactgtatt ttttatatct tcataatctc
      421 ttcctaaacg atctagtgat gtaacgatga cgcaatcacc ttcacggata taatttagta
      481 atttttgaaa ctcaggacgc tcagtatctt taccactggc tttttcttgg aataatttat
      541 caatgttaag tccttccatc attgccaatt gtcgatccaa attttgatct tgtgaagata
      601 ctcgaatata gccaattttt cccataaaaa actccttttt aaaagtgata taatttacat
      661 gtaaaattta cttgtagttt tactgctatc atagcatttt taaaaataaa ttttatgtag
      721 acttaaaatt tacttcatgg agggtttaaa tggatgaaat caaaagtaac aaaaaagcat
      781 ttggcattta tttaggagaa cctagtacag aacaattaaa ccaattttt
//
LOCUS       DACCVZ010000224          783 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.230, whole genome shotgun sequence.
ACCESSION   DACCVZ010000224 DACCVZ010000000
VERSION     DACCVZ010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.230"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            24..716
                     /locus_tag="IVW63_002999"
     CDS             24..716
                     /locus_tag="IVW63_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAP7861194.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT          281 a          151 c          159 g          192 t
ORIGIN      
        1 tgaaaaaaag gattttagta acaattggtc tagctttttt gttagctggt tgtaccaacg
       61 ggaatgaatc gaaaaaagaa tcaacaaaag aaacagcgaa agcaacagtt gcaactacta
      121 caacaactag cacagagagc aagtcaactg cagcaagtac agaaacagca gatacctcta
      181 cttcgtcaga gtcttccaaa acgactgaaa caactcaaac atctacttca agttcttctg
      241 tagaggcttc atcttcctct tcagaaagca gcgaacaagt tgaacaaaca ctgtggaatg
      301 cagacaaatc cgcacaatta gaggcattta tgaccaaatg gggccaaaca atgggacaac
      361 aatacaaaag ttatacgaat caaatgagtg tggacttata tggtcttaaa gtccctcaag
      421 ctattttgaa cggggagtgg aagatggcta ttggtggagt gcctgtttct gcagaatggt
      481 cagaaagtgg gacaggtcaa gcagactatc aaatcacagc cgtctattcc gatgcagaga
      541 cagaaccata tctgaaaaag cacgtctatc tattcgggtt tcagcaaaat cagccaaaag
      601 tattggtgac acaacaaaat caggggaatc ccgataatta tctttacttc aacgagacag
      661 cgaataatga attgaaaaat ggctttaatc aaatcgttta tggacaagca aattaatgag
      721 ataaacaagg ggttgtgaca tgtcttttat cacaacccct tgctcagttt atttgttagt
      781 ctt
//
LOCUS       DACCVZ010000225          706 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.231, whole genome shotgun sequence.
ACCESSION   DACCVZ010000225 DACCVZ010000000
VERSION     DACCVZ010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.231"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>706
                     /locus_tag="IVW63_003000"
     rRNA            <1..>706
                     /locus_tag="IVW63_003000"
                     /product="23S ribosomal RNA"
BASE COUNT          218 a          140 c          206 g          142 t
ORIGIN      
        1 cggtggatgc cttggcacta ggagccgatg aaggacggga ctaacaccga tatgctttgg
       61 ggagctgtac gtaagctatg atccagagat ttccgaatgg gggaacccaa catctttaat
      121 aggatgttac gattgtgtga atacatagca cattcgaggt agacgcagag aactgaaaca
      181 tctaagtacc tgcaggaaga gaaagaaaat tcgattccct gagtagcggc gagcgaaacg
      241 ggaaaagccc aaaccagcaa gcttgcttgt tggggttgta ggactccaat atggtagttc
      301 tttcagatag tcgaatgact tggaaaagtc agtcaaagag ggtaaaaacc ccgtagacga
      361 aatgtggaag acacctagga ggatcctgag tacggcggaa cacgagaaat tccgtcggaa
      421 tccgggagga ccatctccca aggctaaata ctccctagtg accgatagtg aaccagtacc
      481 gtgagggaaa ggtgaaaagc accccggaag gggagtgaaa tagaacctga aaccgtgtgc
      541 ctacaacaag tcaaagcccg ttaatgggtg atggcgtgcc ttttgtagaa tgaaccggcg
      601 agttacgatt gcatgcgagg ttaagttgaa gagacggagc cgcagcgaaa gcgagtctga
      661 atagggcgtt tgagtatgta gtcgtagacc cgaaaccatg tgatct
//
LOCUS       DACCVZ010000226          679 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.232, whole genome shotgun sequence.
ACCESSION   DACCVZ010000226 DACCVZ010000000
VERSION     DACCVZ010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.232"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(86..439)
                     /gene="tnpB"
                     /locus_tag="IVW63_003001"
     CDS             complement(86..439)
                     /gene="tnpB"
                     /locus_tag="IVW63_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAP7861195.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(429..623)
                     /locus_tag="IVW63_003002"
     CDS             complement(429..623)
                     /locus_tag="IVW63_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861196.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          204 a          144 c          115 g          216 t
ORIGIN      
        1 gaatcgaact gattttgtta cagaatacca caagaaacgc acaagaaata ggggttcaac
       61 acattttttg tgttaacccc ccagcttaaa aaactccttt ttttcctggc aaaatagctc
      121 gaggttgatc gatacttaat ccttctaaca accatcgaac ctgttggttc gttaaggttc
      181 gaacttcgtc tttcgtccga ggccatttta acttgccgtt ttctatccgc ttataacaga
      241 gaagaaaacc atcaccgtcc caatagagaa gtttgaaacg gtcttgacgg ttcccgcaaa
      301 ataaaaaaac ggcatcttcg taaagctcga gttgatactc ttgttgaata agactggcaa
      361 gaccatcaat tccttttcgc aaatctgttt ttccgcacac aatataaata tgtttggttt
      421 gaagtaaatc ataaagcatt ggacaacagt tctttcaaaa tagcttgaag aatataattg
      481 ttaataccgt tatagatcaa aacttcagaa ccattctctc ttttgatgcg catcgctaac
      541 ttggcagccg cgggtttacc tttttctggt gcactctttt cgtttcctaa ttggacagga
      601 acaatctcat ttaatttata catagaaaac ctccagactt cttgatagct caagtatatc
      661 ttgaggtgca tttgttagt
//
LOCUS       DACCVZ010000227          652 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.233, whole genome shotgun sequence.
ACCESSION   DACCVZ010000227 DACCVZ010000000
VERSION     DACCVZ010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.233"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            145..576
                     /locus_tag="IVW63_003003"
     CDS             145..576
                     /locus_tag="IVW63_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861197.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            578..>652
                     /locus_tag="IVW63_003004"
     CDS             578..>652
                     /locus_tag="IVW63_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAP7861198.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFV"
BASE COUNT          252 a           95 c          132 g          173 t
ORIGIN      
        1 tggttgggtc aatagaccgt tctactttga acagtgctca actatctatt ggcgcagacg
       61 gagccattaa atggagaaga aattcaagtt atggatcagc ttattcattt gttatcactt
      121 attcaattta agggaggaaa tctaatgaaa gtagtttaca aatcaatcaa gccttacgga
      181 ttcgagcaaa tcattttgaa caatcaagaa aatatccctg aaaactgtac agagattaaa
      241 ccaccagttc ctaactggag accaagattt gattttgata aaaaacagtg ggttgagtta
      301 gctactgaag aagagaaaaa agggaatgct gttgatagcg tagatgaatt ggctaatatt
      361 aaggcattat acgaaacgct gaaggcagaa aatgatgaat tgaaacagct aaattctaaa
      421 gcaatgctaa acaatgtagc aatcaagcaa gaaaatgtct tattgaaaga aaagtcagaa
      481 agtttagcgc agttgaattc aaaaacgatg cttgcttctg tacaaaatac caaggaaatc
      541 gaagaaatca aaaaacaatt acaaggtggg aagtaacatg tattcatatg aagatatcaa
      601 actaatgtat gactggggct gtttcactaa cgaacaagta atggttttcg tt
//
LOCUS       DACCVZ010000228          631 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.234, whole genome shotgun sequence.
ACCESSION   DACCVZ010000228 DACCVZ010000000
VERSION     DACCVZ010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.234"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
BASE COUNT          241 a           80 c           81 g          229 t
ORIGIN      
        1 attagcaata tataaaagaa ggtatcaaga gtcacagtga atttattccg aaaagtgaaa
       61 agagcaaata taaaatttaa taaaaataag aactaaatag gaaaacgtag acgtaatttt
      121 ctacgttttc cttttcatat atattaaata ttacggaaaa ttatataaac taatttagtg
      181 ttttgtttgt aattcctaat tttgctccac ttttagataa tttttaggtc tatttaactc
      241 attagacatt ctatgctcat ttttctccaa atttgtttca actctttcgt acttaatttt
      301 gcgtatttga aaattcttct tttagagtac ttttattacg atactagtat gatatatatc
      361 tacagcaaac agttaaaatc ttcctaaaat aagcgaatag cattcctaaa acctataaaa
      421 tttttagatg aagcgacaag tggacaatta ataaactact tgaacatgaa attatggatc
      481 acctttcaaa tttagaaaat ggaattctta tacttattgc gcaacattta ttgattgcaa
      541 aattatgtga caaaaagaac tagtagaaga aggaataatg gcttgataat aaagtactac
      601 ctattaaagg tagtacttta tttaatttag t
//
LOCUS       DACCVZ010000229          615 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.235, whole genome shotgun sequence.
ACCESSION   DACCVZ010000229 DACCVZ010000000
VERSION     DACCVZ010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.235"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            46..381
                     /locus_tag="IVW63_003005"
     CDS             46..381
                     /locus_tag="IVW63_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861199.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
BASE COUNT          242 a           69 c          108 g          196 t
ORIGIN      
        1 acaatttcct aggaaaaata gttaacataa aaggaatgaa ttgttatgaa acaatattta
       61 aatgaatgga aagcgataga ggggtcatta gtaacgcaaa gaataaagga attacctgat
      121 tgcttagaga aggatcattt gtttcaaata cgagaaatgt tgaaaaaaga acagtttgat
      181 ccagaccaat ttttagtagt cgagtatcca actattggag tgtactgttg taaccatatc
      241 aatgatggaa aatattttat tattcaggag tatggaggac agttaactcc tttctatact
      301 acatgggaaa tgagtgaaga aggaatcaat aattttccat gtgaaagcat cgaagattca
      361 atttcacaca ccgaatgtta attgattata actataaaaa aggattgaac attatgttca
      421 atcctttttt caatgaaatg ttttccgcca tttcattgtt tggtgcgatt tctattttat
      481 tatatcaaaa taaagagaga ttctaaagaa agaagaggga aatatataaa tcaagcgaca
      541 gtatatttat tattaaatgc tattgtgaga atataactaa ttagtttaat ttgaaagtaa
      601 atatacgcta taaaa
//
LOCUS       DACCVZ010000230          583 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.236, whole genome shotgun sequence.
ACCESSION   DACCVZ010000230 DACCVZ010000000
VERSION     DACCVZ010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.236"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            87..>583
                     /locus_tag="IVW63_003006"
     CDS             87..>583
                     /locus_tag="IVW63_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HAP7861200.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          221 a          106 c           94 g          162 t
ORIGIN      
        1 taaatgaaaa aatccataca aaaaaggaag tcccttctgt agaataaagt taacgacaac
       61 caattcacag aaaagaggac ttccctatga atgattttac tacagaaatt gtgcaaactc
      121 tagtcactaa aggcgattta aatgaattat tccgttcgca cttagaaaaa gcgataaaca
      181 cactcctacg gactgaatta acggcttttt tagattacga aaaatatgat cgcactggtt
      241 ttaattcagg taattcgaga aacggttctt actttcgatc aatcaaaacc gaatatggtg
      301 aattaacatt ggaaatacct agagatcgta atggtgagtt taaacaacaa actttaccag
      361 cctacaaaag aacaaacgat acattggaaa ccactattat ccatttattc gaaaaaggtg
      421 ttacgatgtc tgaaattgct gatttgatcg aaaaaatgta cggtcatcac tatactccac
      481 aaaccatgtc caacatgact aaagttctga ctgaagaagt aaatgccttt aaatccagag
      541 ccttaaatga taagtatgtc gctattttta tggacgctac tta
//
LOCUS       DACCVZ010000231          528 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.239, whole genome shotgun sequence.
ACCESSION   DACCVZ010000231 DACCVZ010000000
VERSION     DACCVZ010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.239"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(5..90)
                     /locus_tag="IVW63_003007"
     tRNA            complement(5..90)
                     /locus_tag="IVW63_003007"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="IVW63_003008"
     tRNA            complement(107..178)
                     /locus_tag="IVW63_003008"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="IVW63_003009"
     tRNA            complement(190..262)
                     /locus_tag="IVW63_003009"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="IVW63_003010"
     tRNA            complement(280..361)
                     /locus_tag="IVW63_003010"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="IVW63_003011"
     tRNA            complement(369..441)
                     /locus_tag="IVW63_003011"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="IVW63_003012"
     tRNA            complement(445..517)
                     /locus_tag="IVW63_003012"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DACCVZ010000232          523 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.240, whole genome shotgun sequence.
ACCESSION   DACCVZ010000232 DACCVZ010000000
VERSION     DACCVZ010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..523
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.240"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>523
                     /locus_tag="IVW63_003013"
     CDS             <1..>523
                     /locus_tag="IVW63_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HAP7861201.1"
                     /translation="WVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAI
                     DADGLTLDIWLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFY
                     QGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTL
                     FGFSVCTEIKVLLG"
BASE COUNT          188 a           91 c          106 g          138 t
ORIGIN      
        1 gttgggtgca agaatatggc aaactactct atcaaatttg gaaaaagaaa aataaaaaat
       61 ccttttattc atggaaaatg gatgaaacgt acatcaaaat taaaggaaaa tggcattatt
      121 tgtatcgagc catcgatgca gatggtttaa ccttggatat ttggttacgt aaaaaacggg
      181 acacacaagc agcctatgct tttcttaagc ggttagtgaa gcagtttgat gaaccgaagg
      241 ttgtagtcac agataaagcc ccctctatta caagtgcctt taagaaacta aaagaatacg
      301 gcttttatca agggacagaa catcgtacca ttaaatacct gaataatttg attgaacaag
      361 accatcgtcc agtaaagaga cgcaataaat tctatcgaag tttacgcact gcctctacca
      421 cgattaaagg catggaagcc attcgaggat tatataagaa aacccgaaaa gaaggcactc
      481 tcttcgggtt ttcggtctgt actgaaatca aggtattatt ggg
//
LOCUS       DACCVZ010000233          513 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.241, whole genome shotgun sequence.
ACCESSION   DACCVZ010000233 DACCVZ010000000
VERSION     DACCVZ010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.241"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(107..>513)
                     /locus_tag="IVW63_003014"
     CDS             complement(107..>513)
                     /locus_tag="IVW63_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_465591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAP7861202.1"
                     /translation="TPENHFSNQISLNVYSRGMGGLGLPGDLSSVSRFVKATFTKMNA
                     ASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSCCNVDKGIYYYRTYEDS
                     QITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT          162 a          102 c           78 g          171 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttc
//
LOCUS       DACCVZ010000234          506 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.242, whole genome shotgun sequence.
ACCESSION   DACCVZ010000234 DACCVZ010000000
VERSION     DACCVZ010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..506
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.242"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>506
                     /locus_tag="IVW63_003015"
     CDS             <1..>506
                     /locus_tag="IVW63_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP7861203.1"
                     /translation="KSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSA
                     RTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSIT
                     FDCGKEFS"
BASE COUNT          167 a           89 c          103 g          147 t
ORIGIN      
        1 caaatcaaac tgtggtagac gtccgcttgt tttacccgag gaacaatcag aatatattca
       61 aagaaaggtt gttcaaggat ggacacccga tgtgattgtt ggtcgtgcag cgtttcctat
      121 tagttgttct gctcgtacca tttatcgtat gttcaaaaag gggctatttg attcttctga
      181 cttaccgatg aaaggcaagc gtaaaccgaa tggacatcaa gaaagacgtg gaaaacaaac
      241 tttccgccgc tctattcatg aacgtgaaaa ggattatagc caattctcaa atgagtttgg
      301 tcaccttgaa ggtgacacta tcgtaggtct gaaacataaa agtgctgtaa ttaccttagt
      361 tgaacgatta tcaaaagtta tcatcacatt gaaaccgtgt ggtagacaag cgattgatat
      421 tgaaaaaaaa ttaaatcaat ggtttgaatc tgtaccgaaa aacctattca aatccatcac
      481 ttttgattgt ggaaaggaat tttcaa
//
LOCUS       DACCVZ010000235          498 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.243, whole genome shotgun sequence.
ACCESSION   DACCVZ010000235 DACCVZ010000000
VERSION     DACCVZ010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.243"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
BASE COUNT          169 a           91 c           69 g          169 t
ORIGIN      
        1 ttttacactc tctattattc ttttcataaa tattgtaaat agaagtatta aaaatatata
       61 caaaaagtat tatttcgaga aagataaata ttttcaaaaa ccttttcata atcctcaccc
      121 tttcttacac tgataaatca tgcgtctaat attcaaatta tactcgatat gctttagcta
      181 atcagccaac tctgtttgtc tactatcatt atatcaatag acaatatctg ctcccgtctt
      241 tatgatcgtg ccaaagcaat caaaagaaaa ttgcgaatca cttagatcga aagtttactc
      301 aaacaaaagc attgtcagcg gttgtcacgg atttaactta tgttcgggtc gggacaaatt
      361 gggcttatat ttgtttgatg attgatttat tcaatcgtga aattattggc cattcttgcg
      421 gaaataaaaa agatgcgcag cttgtaaaaa gggccattca aagcattcct tactcacttc
      481 aagaaatcga actcttcc
//
LOCUS       DACCVZ010000236          496 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.244, whole genome shotgun sequence.
ACCESSION   DACCVZ010000236 DACCVZ010000000
VERSION     DACCVZ010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.244"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
BASE COUNT          164 a           96 c           58 g          178 t
ORIGIN      
        1 agaatgctaa atcactctac aataacggcg aaagcacaaa aaataaaaaa attattacgt
       61 tattaaaaaa acagatgaaa gatcaggttt tattagatct cattctttca tcacttgaag
      121 ggatttaatg aactactttt tcctctttgt cgtttttata tattcgtatt ccttcaaaca
      181 gtaggatagc ctctttcaat gcttgatatt tgaactgtcc gttacttaaa aatttagatg
      241 tgccgccctc ttcctagaac atattctttt ttactttttc attaattgac agaccaatcg
      301 aacgaaactg taaatttcga taggataatg attggtcaaa ctcattcatt ttcaagacat
      361 ctcgattcat attcaagata ggaatctttt tatcaacatc actttattcg tattttcctc
      421 taccataaaa gcttcacgct ccacaaaatt gttttataca ctactattca gcccattcaa
      481 cgaccaatga attttt
//
LOCUS       DACCVZ010000237          491 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.245, whole genome shotgun sequence.
ACCESSION   DACCVZ010000237 DACCVZ010000000
VERSION     DACCVZ010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.245"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>491
                     /locus_tag="IVW63_003016"
     CDS             <1..>491
                     /locus_tag="IVW63_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP7861204.1"
                     /translation="FPSRSRFTRLSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSP
                     LCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVK
                     VLETLSEEANLPNILGDKGYISHKIHEKLALKGITISVPPRKNMDKSEKLDHSLLGKQ
                     RKT"
BASE COUNT          179 a           96 c           80 g          136 t
ORIGIN      
        1 ctttcctagt aggagtcgat tcactcgctt aagttcaaac ttagcttaca ctatcaagat
       61 tattcgatac tttttcatca agaagctcac caaaggtgaa ctagtcggaa ttatagatag
      121 ttttcctagt ccattatgta aaccagttag aaatagacaa gcaaaactat tgaatcaaat
      181 agccaaagtt ggctataact caacaaaaaa atcttatttt tatggtctta aaattcatat
      241 gatcgttact aagactggct ttccgattac ttactcaatc acgaatccag gtgtccatga
      301 cgtgaaagtg ttagagactt tatcggaaga agcgaatctt cccaatatcc taggggacaa
      361 aggatatatt agccataaaa tccatgaaaa gcttgccctt aagggcatta ctatatccgt
      421 tccgccacgt aaaaacatgg ataaatcaga aaaactagac cacagcttac ttggaaaaca
      481 aagaaaaaca g
//
LOCUS       DACCVZ010000238          470 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.246, whole genome shotgun sequence.
ACCESSION   DACCVZ010000238 DACCVZ010000000
VERSION     DACCVZ010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.246"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>470
                     /locus_tag="IVW63_003017"
     CDS             <1..>470
                     /locus_tag="IVW63_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
                     /protein_id="HAP7861205.1"
                     /translation="ALSKRGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKT
                     TNVLNRKFLRDNPLEAIVTDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLV
                     KKAFSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAV"
BASE COUNT          167 a           78 c           88 g          137 t
ORIGIN      
        1 aagccttatc aaaacgaggc attcagatca gccgacgaaa aattagtaga atcatgaaaa
       61 atagaggatt aaaatcgagc tatactgttg cttattttaa agtacatcat tctacttgca
      121 atgaagccaa aacgacaaac gtattgaatc gtaaattctt aagagacaac ccattagaag
      181 cgatcgtaac agacttgact tatgtacgag tcgggaaaaa atggaattat gtctgtttca
      241 ttttggatct gttcaatcga gaaattctcg gctattcttg tggagaacat aaagatgccg
      301 ttctagtaaa aaaagcattt agccgtatca aacaacctct gacagaggtt gagatttttc
      361 atactgatcg tggaaaagag tttgataacc aagctattga tgaattatta acaacttttg
      421 acatcaatcg atcattgagt cataaaggct gtccttttga taatgccgta
//
LOCUS       DACCVZ010000239          449 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.247, whole genome shotgun sequence.
ACCESSION   DACCVZ010000239 DACCVZ010000000
VERSION     DACCVZ010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.247"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>449
                     /locus_tag="IVW63_003018"
     CDS             <1..>449
                     /locus_tag="IVW63_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861206.1"
                     /translation="IFTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKW
                     PEEATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDASEGIKNKEDL
                     PKDTKYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRS"
BASE COUNT          180 a           68 c          105 g           96 t
ORIGIN      
        1 atcttcaccg caggggaagg aacaagtatt gaaagtggaa caacggtctt tgcagtgaaa
       61 gacggcgtaa gcttaccaga agataaactt ccagtgttga aagcaaaaga tggttataca
      121 gatgcgaaat ggccagaaga agcaactcaa ccaattacag cagatgatac agaatttgta
      181 tcaagtgcaa caaaactgga tgataaatct gacgctgaca aatataatcc tgaaggtcaa
      241 aaagtgacta cagaattgaa taaggaacca gacgcatctg agggaattaa gaacaaagaa
      301 gatttaccaa aagatactaa gtatacttgg aaagaaaaag tagatgttag cgcagctgga
      361 aataaaaaag ggactgttgt agtgacatat ccagatggat catctgatga agttgaagta
      421 gatgttacag tgacagacaa tcgttctga
//
LOCUS       DACCVZ010000240          443 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.248, whole genome shotgun sequence.
ACCESSION   DACCVZ010000240 DACCVZ010000000
VERSION     DACCVZ010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.248"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
BASE COUNT          186 a           61 c           73 g          123 t
ORIGIN      
        1 aataatcatt attatcaaaa taatgttaaa aataaaaaag aattgtccat cactgttatt
       61 caaatcattt tatcaaaact acatagtaaa tgttaaaaag caacatgaca taatatatag
      121 aaggctttac agtatatatg ggagcttact aaaaaagaat ggagtaagag ttaacacaat
      181 gggccattag ctgaagtttt aagcacttca aggtatgaaa cagaatggcc tgtaatacta
      241 catgattatt tagactgctc aaactgctat cagtctggtg gaatgaataa agtattatac
      301 taaaagcaga tccaactaca acgtaacagg aaaccagttg tatcaggaaa agtgatagta
      361 catggagaag aaaaggcccc ctttgtatga gtcagtacat atcttattta tagataaaac
      421 ggtattcaat cgaaataaaa aat
//
LOCUS       DACCVZ010000241          421 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.249, whole genome shotgun sequence.
ACCESSION   DACCVZ010000241 DACCVZ010000000
VERSION     DACCVZ010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.249"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..390
                     /locus_tag="IVW63_003019"
     CDS             <1..390
                     /locus_tag="IVW63_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP7861207.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          163 a           74 c           65 g          119 t
ORIGIN      
        1 aaagaccgaa aagaaatctg tgatgacttt aaggctgttt atcaagctaa ctcaaaagaa
       61 gaagcgaata ccttcttatc cggcatgatt gagaaatgga agaaaaacta tcctaaagtg
      121 acgcagtcac tcatagaaaa ccaagactta ttaacttttt atgattttcc acctagcatt
      181 cgtagaacca tttactcaac caatctaatc gagtctttca ataagcaaat taaaagatac
      241 agccgtagaa aagagcagtt tcaaaatgaa gaatcactag aacgctttct agtcagcatt
      301 tttgatacat acaatcaaaa atttctaaac agaagccata aaggttttca acaggtaacc
      361 gatacattag tttcaatgtt tactgagtaa ctaattattt tgcaggagga caatttattt
      421 a
//
LOCUS       DACCVZ010000242          415 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.250, whole genome shotgun sequence.
ACCESSION   DACCVZ010000242 DACCVZ010000000
VERSION     DACCVZ010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.250"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..339)
                     /locus_tag="IVW63_003020"
     CDS             complement(<1..339)
                     /locus_tag="IVW63_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP7861208.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DACCVZ010000243          375 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.251, whole genome shotgun sequence.
ACCESSION   DACCVZ010000243 DACCVZ010000000
VERSION     DACCVZ010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.251"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..132)
                     /locus_tag="IVW63_003021"
     CDS             complement(<1..132)
                     /locus_tag="IVW63_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP7861209.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          132 a           69 c           76 g           98 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaat
//
LOCUS       DACCVZ010000244          332 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.253, whole genome shotgun sequence.
ACCESSION   DACCVZ010000244 DACCVZ010000000
VERSION     DACCVZ010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.253"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(60..>332)
                     /locus_tag="IVW63_003022"
     CDS             complement(60..>332)
                     /locus_tag="IVW63_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP7861210.1"
                     /translation="FKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLYYSNKNYFKI
                     PATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
BASE COUNT          107 a           64 c           49 g          112 t
ORIGIN      
        1 cccttttata agtatggtga taaaatccgt tccgggctac cttttttagg tagcctactt
       61 taatctttat acctttctgg atcaacgaaa gtatacttca aatagtcata acgccgatga
      121 tcgctccgtg cgtctggcac atcagtcacg atatcaaaca aaaaatacac atctttcttc
      181 attctggttt ttgttgccgg aattttaaag tagttcttat tagagtaata gagattgatt
      241 aataagctat cttcgattgc taaaaagaaa acttctgaat cccacacctt ataaaaatct
      301 ttgacaaatc tattcgaagg atcaaattta aa
//
LOCUS       DACCVZ010000245          325 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.254, whole genome shotgun sequence.
ACCESSION   DACCVZ010000245 DACCVZ010000000
VERSION     DACCVZ010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.254"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..>325
                     /locus_tag="IVW63_003023"
     rRNA            <1..>325
                     /locus_tag="IVW63_003023"
                     /product="23S ribosomal RNA"
BASE COUNT           98 a           63 c           94 g           70 t
ORIGIN      
        1 cgaacccacg tacgttgaaa agtgcgggga tgaggtgtgg gtagcggaga aattccaaac
       61 gaacttggag atagctggtt ctctccgaaa tagctttagg gctagcctcg gaattgagaa
      121 tgatggaggt agagcactgt ttggactagg ggcccatctc gggttaccga attcagataa
      181 actccgaatg ccattcattc atatccggga gtcagactgt gagtgataag atccatagtc
      241 gaaagggaaa cagcccagac caccagctaa ggtcccaaaa tatatgttaa gtggaaaagg
      301 atgtggggtt gcacagacaa ctagg
//
LOCUS       DACCVZ010000246          323 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.255, whole genome shotgun sequence.
ACCESSION   DACCVZ010000246 DACCVZ010000000
VERSION     DACCVZ010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.255"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..302)
                     /locus_tag="IVW63_003024"
     CDS             complement(<1..302)
                     /locus_tag="IVW63_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HAP7861211.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT          100 a           49 c           51 g          123 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgttatatc aactcatttc ttg
//
LOCUS       DACCVZ010000247          298 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.denovo.256, whole genome shotgun sequence.
ACCESSION   DACCVZ010000247 DACCVZ010000000
VERSION     DACCVZ010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.denovo.256"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
BASE COUNT          105 a           53 c           43 g           97 t
ORIGIN      
        1 ctctataatt tctaggactg atggaaattt tctatctgtc ctagtttttt tgtaaaaaaa
       61 caaaaagaca tacaaaattt ccggtagaat agagtctcct acaacatcat tctgggggaa
      121 ttcttgtatg tccatgaatc attttatcaa acaactcttt actattaaag actcaaatat
      181 ccaaattcaa tcctttgaag aaacttttta taaaagcaga aaaagtatcg ttattgaggg
      241 aactctgatc cgtacctaca gacgttgtcc gtgttgtaaa gattctacaa agcaaatc
//
LOCUS       DACCVZ010000248        16214 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.guided.063, whole genome shotgun sequence.
ACCESSION   DACCVZ010000248 DACCVZ010000000
VERSION     DACCVZ010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16214
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.guided.063"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(134..577)
                     /locus_tag="IVW63_003025"
     CDS             complement(134..577)
                     /locus_tag="IVW63_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAP7861212.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="IVW63_003026"
     CDS             complement(795..2135)
                     /locus_tag="IVW63_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7861213.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="IVW63_003027"
     CDS             2404..3300
                     /locus_tag="IVW63_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAP7861214.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="IVW63_003028"
     CDS             complement(3450..4391)
                     /locus_tag="IVW63_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAP7861215.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="IVW63_003029"
     CDS             4517..5638
                     /locus_tag="IVW63_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP7861216.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /locus_tag="IVW63_003030"
     CDS             5896..7398
                     /locus_tag="IVW63_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAP7861217.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7465..7992
                     /locus_tag="IVW63_003031"
     CDS             7465..7992
                     /locus_tag="IVW63_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP7861218.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="IVW63_003032"
     CDS             8203..9264
                     /locus_tag="IVW63_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP7861219.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="IVW63_003033"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="IVW63_003033"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAP7861220.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="IVW63_003034"
     CDS             10177..12159
                     /locus_tag="IVW63_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7861221.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="IVW63_003035"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="IVW63_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAP7861222.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12881..14305
                     /locus_tag="IVW63_003036"
     CDS             12881..14305
                     /locus_tag="IVW63_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP7861223.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14486..15259)
                     /locus_tag="IVW63_003037"
     CDS             complement(14486..15259)
                     /locus_tag="IVW63_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP7861224.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15256..16161)
                     /locus_tag="IVW63_003038"
     CDS             complement(15256..16161)
                     /locus_tag="IVW63_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP7861225.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
BASE COUNT         5207 a         2949 c         3372 g         4686 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcat tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt tttaagtttt
    12721 ttggtggtgt aatttggaaa gggactaggc gctttgcttg tataatgaga aaaaagccgg
    12781 tagaattata tttctattaa agtttttatt aattaagtaa aaataaaaaa ggtttgttat
    12841 actttttgat aaaagcggtt ttattttgga ggatgcttac atggatacag agcaacagaa
    12901 aaaaggaatt ggtttaattc cacttgctgc cttagtaatt ggttcagcga ttggaggtgg
    12961 cgtatttggt attatgacgg acatctccgg atcggctggc ggcccagcta ttttcagttg
    13021 ggtactcgta ggaacagcaa tgttgatgct ctccttgtcg atcaataata tcaataaaaa
    13081 acgtccagat ttaaaaggcg ggatctttag ttacgcagaa gaaggttttg gccgtttcgc
    13141 tggttttatc agcggttggg gttactggct cacatgctgg ttaggcaacg tagcttttgc
    13201 aacattgttg atgagcgcat taggatattt cttcccagta tttgaaggtg ggcaaaatct
    13261 ggcatcgatc gtgatgagta cagtcttttt atggggatat gcatggctag tgaatcgggg
    13321 agtcgaaaat gctagtttcg tcaatgctat cgtcacattc tgtaaattag tgccattatt
    13381 tttatttatt gtagtagcta tcagcacgtt ttcgatccaa caattcattg ataacttttc
    13441 tagcgacatt atattgaatg cgaatggaca gccgatcccg ttttccagtc aagtattgag
    13501 ttgcatcatg gtgatgcttt gggtatttgt tggtattgaa ggagcctctg tcgtaggttc
    13561 acgagcaaaa aaacaatcag atgttgggaa agcaacgatt ctagggatat tcggcttgat
    13621 tattatttac gtcttggttt ccatgcttcc atatgggaca atgacgatga atcagctgca
    13681 aacgatcaag gcgcagcctg ctatgggcta tgtgtttgaa atgatggttg gtaaatgggg
    13741 agcagtcgtg atcaacggcg gtttgatcat ttctttagtt ggtgtttggc tctcatggac
    13801 gatcttaccg attgaaacaa tgggaaacat ggctgaagac ggacttttgc ctaaagcatg
    13861 gggaaaactc aacaaaaatg gggcaccaac ttatgctatc gtattgacga cgttatgtac
    13921 gaatgtcttt ttactttcat tattattcac tgacagtgct tataactttg cttacacact
    13981 tggtacagca gctattttct tcacgtggct tttcttagga ttgtaccaaa tgaaactttc
    14041 ttatcagcgg aaagaatggg tccaattttt agtagggctt ttagcaagtg cctttcaagt
    14101 atgggctatg ctagtcgtag cctttaatga agtaatgctt gttcttgttc ttttcttgcc
    14161 aggcatttat ttttacctca aagcacgtaa ggagcaaaac gagcctgtac aacatatcca
    14221 cttagataag attttactta taggtgtgac gatggtcgga gtgattgcaa tggttttatt
    14281 tgccactggg atgcttcacg tatagaagta taaaagaagt ataaagagag gttgtgagcc
    14341 tgtcgtttat tcaaaaacat actaggaaag gagctgtgac acaaatgttg tcacagctcc
    14401 tttttcagaa taaacggtgt ttaagagaca gccaatcggc aataaggctg aacgtctctt
    14461 tcacagcctc ttttttgatg agtcatcata cattttttcg cttaaatacg agatatccta
    14521 atgctaagaa caaaacgatg taagctaaat taccgaatag catttgatta gtagaaagat
    14581 gagtcaattg cttcatgatc tcttcgtttc caatttggtt ttgcagattc aacatactga
    14641 tcggattcca tttgatccac tcccattttt ggatgagtgc aataaggata ccagatatga
    14701 ttgacgaagc aaaataaaag acgattcctg ctgagatgga tgcgccggaa ctattgataa
    14761 agcaagcaat catcaacact aaacttaaaa tcagccataa accgatataa ctacccaaag
    14821 tataagtgaa caagctttgg atcagtgttt gaccagtaga aaccttctcc gtgaaggaaa
    14881 tcgaagggaa aagaatcagt ttcatcaaca cagtgacaat aatagctaaa aggtataaat
    14941 aaacagaata aataactaat gtgatccatt tgcttactaa tatttctcct cgagaatact
    15001 ttcgataaag gagatttttc aatgtaccat attgtgcttc catcgaaatg atcgtgcttg
    15061 cagctgcaat catgataaag acaatccaag atgtggcact aaaaagctga gcagtcattt
    15121 caactggatc aatgatcgtc gtgtattttt tggctagaag tgctgttcct atgagcaaaa
    15181 caactaatag aacagataaa acagcagttg actttttctt gatcaattta aataattctt
    15241 gttttacaag caatgtcatt tttcttcttc cccctttact gaatccagaa tttccaatag
    15301 agaagattcc aaatcattcg tcagatgctg gacgtctgtc acatggatat tttgtgcaga
    15361 caatagctgg atcacggttc ctaataattc ttcgttttct tttaaaagct tgattttatc
    15421 aggatcttcc aaagtatatc cagcttctgt caagatcgtt cgagcagcta gatcatttgt
    15481 tgtagagata acgatgaaat cttgcgctgt ttggttcaat tcagccattg tacattgttt
    15541 gatgatcttt ccttgattga tcaggatcag ctcatcgacc attttttcaa gctcgctgag
    15601 taagtgactg gagatcaaga aagaggtgcc ctgagtagcc aagtcggtaa tgatttttcg
    15661 cacatctctt gttgcttgtg gatccaaacc gttcatcggc tcatctaaaa taacgataga
    15721 cggatggttc agtaaggcaa gagcaattcc caatttttgt ttcattccca acgagtagga
    15781 tttcgctttt ttgtgaatgt acttttccat cttgagctga ttcacgatag tgtcgatagc
    15841 agatacatcg ttggtttcag agaataactt cagatgatca tagcctgtta agaatggata
    15901 gatacccggg tattcgatca atgctcctac ttgttccaac cctttatgac tagagggaga
    15961 aatctcattt tcaccaatac agattgttcc atctgagtaa tggatcagtc ctaaaatagc
    16021 tttcatgatc gttgtttttc cagcgccatt aggacctact aatccaacga ttttgccagg
    16081 ggataagcta aaactgacat cgctgagggc ttgtttgtga ccaaagttct tggataattc
    16141 ttggaccgaa agacttttca aaaatattca ctccttttct atagatagta caagcataca
    16201 cctgatgagt ggag
//
LOCUS       DACCVZ010000249        15555 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.guided.064, whole genome shotgun sequence.
ACCESSION   DACCVZ010000249 DACCVZ010000000
VERSION     DACCVZ010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15555
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.guided.064"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            109..591
                     /locus_tag="IVW63_003039"
     CDS             109..591
                     /locus_tag="IVW63_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP7861226.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(854..1321)
                     /locus_tag="IVW63_003040"
     CDS             complement(854..1321)
                     /locus_tag="IVW63_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAP7861227.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            1444..2295
                     /locus_tag="IVW63_003041"
     CDS             1444..2295
                     /locus_tag="IVW63_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7861228.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(2546..4504)
                     /locus_tag="IVW63_003042"
     CDS             complement(2546..4504)
                     /locus_tag="IVW63_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP7861229.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(4501..5373)
                     /locus_tag="IVW63_003043"
     CDS             complement(4501..5373)
                     /locus_tag="IVW63_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP7861230.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(5715..6587)
                     /locus_tag="IVW63_003044"
     CDS             complement(5715..6587)
                     /locus_tag="IVW63_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP7861231.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            6715..7284
                     /locus_tag="IVW63_003045"
     CDS             6715..7284
                     /locus_tag="IVW63_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAP7861232.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            7351..8088
                     /locus_tag="IVW63_003046"
     CDS             7351..8088
                     /locus_tag="IVW63_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP7861233.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            8319..9587
                     /locus_tag="IVW63_003047"
     CDS             8319..9587
                     /locus_tag="IVW63_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAP7861234.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            10074..10538
                     /locus_tag="IVW63_003048"
     CDS             10074..10538
                     /locus_tag="IVW63_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP7861235.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            10522..11151
                     /locus_tag="IVW63_003049"
     CDS             10522..11151
                     /locus_tag="IVW63_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP7861236.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            11505..12983
                     /gene="msr"
                     /locus_tag="IVW63_003050"
     CDS             11505..12983
                     /gene="msr"
                     /locus_tag="IVW63_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAP7861237.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            13030..13476
                     /locus_tag="IVW63_003051"
     CDS             13030..13476
                     /locus_tag="IVW63_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAP7861238.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(13675..14190)
                     /locus_tag="IVW63_003052"
     CDS             complement(13675..14190)
                     /locus_tag="IVW63_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP7861239.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            14307..15509
                     /locus_tag="IVW63_003053"
     CDS             14307..15509
                     /locus_tag="IVW63_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP7861240.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4886 a         2794 c         3227 g         4648 t
ORIGIN      
        1 aaaaaatagt taaaaaataa aaatatccct agaaaaaaga gcgtaatcgt gtcatttccc
       61 tttaatttta tgtaagatga acttaatata atagaaaggg tgggagaaat ggcaaagtat
      121 aggatcgaag aaaaaccaga ttttacggtg acgggtattg gtgtggaatt gaagagtagc
      181 aatacggatt ttgtcggttt ggctgcagag aaacaagcat ttgagcaaaa agttatcggt
      241 aatggaacaa tagatgcatt gaaacaagct gctgaaaatc attatttctt tacagtcaac
      301 gaaccctata acgggaaaat gatgtactat gtcggtgttc aaacgagtca ggatgttcca
      361 aacactacgc gaatcatccc attcccaaaa ggaacgtatc ttgttgtaag cgctttagca
      421 gaatcgcctg aagaattaag aaatgatttg acgaatacgg cctttgggca tgttttaaga
      481 gaagtagaag attacgccta tgttgggggt ccaaatgctg tagtcgaaat gggagttacc
      541 aacgggaaat atatgggaga aatctggata ccggtagtca ataaaccatg ataatataga
      601 ggtcgtgaaa gtagcgcttt gacctgagca ttagagagga aaaatgggaa atagctttcc
      661 atattttgca tttttcagaa ctaatgccga gggtcagcta cttgaacacc gtttatcaag
      721 acgtcatgac ttcagcgctt tgacctgagc attagagagg aaaaaggggc atgacaaggc
      781 ttttgtcccc cggagaataa aagaatttat gtagacgatt ccgatcagaa aaatgcaggc
      841 acagtagaga gaattataaa aatctctcta cgaggcctgt gttttctggt cttttttctt
      901 tttccaaaac ggctatttta tgtatcagac tatcaagtgt gatcttagcc atttcttctt
      961 ctgccttttt ctgcagccga gcgtagcttt cttctaaagc ttcttggata ttcgcaccaa
     1021 cgacgcaatt tggatttgtt tttggatcga cttggataag ctgtgtatta ccttcgatgc
     1081 tgcgatagac atctagtaaa gaaatctgat ctggactttt ggcaagggaa ggctgcggtt
     1141 ttccggtttt tgtaaagatc aaaccggatt ttttgagctg actcatgatt ttacgtacat
     1201 ttgctgcatt tgtttcgata ctactggcaa tcatctcact agaaagtgat cgggtatctt
     1261 gaaacatttc aatataggca agtacatgga ttgcatcact aaattgcaga gaatacttca
     1321 tcagttgtca tcctttcatt ttttttgctt gacttatctt accacactct ttatgataaa
     1381 ggtgtaattt ataaatgtac agctgtaaat cttaacaaat aaaaagaata gggagtggca
     1441 aatatgcatt atttagtaac aggagcaact ggaggttttg gtggttatgc gctggaattc
     1501 ttaaaaaaga tggttccaca aaatgaaatc tatgtactag tacgtagtga agaaaaagga
     1561 gaagcactga aagaagctgg atttaatata cgtattggtg attatgatga tttagactca
     1621 atgaaagaag cgttgaaagg aatagatcga ttgctttttg tctctggcgt tccaggaaat
     1681 cgtcaagccg aacataagaa tgtagtgaag gcagcacaag cagctggggt atcttatatc
     1741 gcttatacaa gttttgcaga tgccgatcac tcgatcagtg tattagcgcc agatcaccaa
     1801 ttcactgaaa aaatgattaa ggattcaggt atttcccata catttttacg gaataattgg
     1861 tatgtagaga atgaattacc tatcattggg caggctttaa aaactggtca attcgtttat
     1921 gctgcaggaa atggaaaaac aggttgggca ttgaaacgtg aatatgcaga agctgcagca
     1981 aaagtactag tagaaagtga ctctccagaa atcttagaat tatccggcaa tctaactgac
     2041 tatgaagaat tagccaaggc attagagcgt gcgacaggta aagagttaga aattattgaa
     2101 gcaagtgatg cagcgtttgt cgaaaatcta aaagaagccg gattccctca agaagcagct
     2161 gacatgtttt tagcgatcca acatgatatt aaaaaggatc agttagctat ttcctctgat
     2221 gatttagaaa aagtattggg aaaaccatta acttctcttg aagcagcatt aaaagaaata
     2281 ttggatcagg aataatgtat aaagaggttg tgaaaaagcc gattagtttt gagtatgaag
     2341 aaaaattttg tgaaaaagct gttctgcatc aagtaataag aagagtcaaa taaaaaatag
     2401 ctcttcatat gtttcgttta gctggactta ttaccgcgga gttggcagga gaacgccgtt
     2461 tttattcgga aaaaggagct gagacaagat ttttgtctca gctcctgttt gtttatcgat
     2521 aaaaaagtct ggggaagacg atggctcagg ctttgttgga aacagagccg attttatcat
     2581 ttgcttttac atcacgtgcg ggttcgattt ctaagctttg gactttgtcg ccatttgtga
     2641 atacaacgac catatccgtg tttttgcctg cagattgaat agcggcaaga tcaactaaag
     2701 caatcaattg acctcttgcg actttttgac cttcttctac atataaagtg aatggttcgc
     2761 cttttaagtc aacagtgttg atgcccatat gaagcaagac ttcgatacca gcatctgttt
     2821 ggattccgac agcatgtttc gttgggaaaa tgtttgtgat cgtaccagcg attggagaga
     2881 agatttctcc attttctggt aatacagcat agccgtcacc catcattttt tccgcgaata
     2941 catcatctga aacttcagtg attggaatca gtttcccatt tgcgatagcg taaatatctt
     3001 gttcgatcgt ttcaccggca aatgtttctg ttttaaccac ggtgtttgtt tgtgcaggtc
     3061 gtgctgcagc accaccatgt agttttgcca tctcatctgc aacgaattgt acttctgtac
     3121 ctacgatgac ttgcgcattt tttccgtcga tgatcttcat accaggtacg ccagtggctt
     3181 tgattttatt ttgatcgatc aggcctgtat ctttgacttg caaacgaagg cgtgtagtac
     3241 agttatcgat cgaagttaca ttgtcggctc cgcctaatgc agcgtagatt ttgcttgctt
     3301 gtgccgcata tttattgtct gaattagtcg ttgcagtatc gtcatctgaa agatctgctt
     3361 cctcgcggcc aggagtcatc agatggaatt ttttgatagc aaagttaaag ccaaagtagt
     3421 aaatcactgc tgttactaat ccttggacga tcaacatcaa tggctgattc gcaatcggat
     3481 ttttcaaaga taggaagtaa tcgacaaatc cggcactaaa ggcaaatcct gctgtccaat
     3541 ggaagaatgc actcactgct aaagaaatcc cagtgaaaat tgcatgcaag acatataatg
     3601 gccaagcaac gaacataaat gaaaattcaa gtggttctgt cacaccagta aagaatgaag
     3661 caaaagctgc tgctagcatc aaggaagctg tttttgcttt gttttctgga cgtgcatttc
     3721 tgtaaatagc atatgctcct gctggaagcc cgaacatcat gattgggaaa aatccagctt
     3781 gatacattcc tgttacgcct tttgttcctt cagaagccaa aaatttacca atatcattga
     3841 ttcctgctac gtcaaaccag aacacggagt tcattgcttg atgcaatcct gtagggatca
     3901 gtaaacggtt gaagaagcca taaagacctg caccacccca gcctaaactc aaaatgaatt
     3961 tagcaaaaga aactaaagca gagtaaaccg gaggccatac gagcagtagc actgcactga
     4021 tcagcaacat gacaaaggca gccaagattg gcactagacg cttgccgcta aagaaagata
     4081 aagccatcgg taattttgct tcgtggaaac gattataaag agctgccgca atcaatccgg
     4141 caataatacc aataaatacg ttactgatct gagcaaaaga tggatcaact gattctggtt
     4201 tgatattcaa taaagtagct actgaatcag tttttaaaac atttactgga acttcaaatg
     4261 cgaccaaacc tgccaaggca gcagcacctg atttgtccac tgacatccct agtgctaacc
     4321 caacggcaaa cagcaaaggt aattgaccta aaactgcgtt accgccagct tgtaaaaaat
     4381 gagcgacaat gtcgttacta taagatgccc accagtttcc gatccctact agtaaagcag
     4441 cagcaggtaa gaccgcaact ggaagttgaa gggaacgtcc cattcgttgt agatatgctt
     4501 tcaatttttt tcctcctcat gattgttaac atttgtttgt acgattgcgc ttcttaaacg
     4561 ctcgatatgg atggccaagt aacccagttc ttctttcgtg atcgcgagct ggtattcttt
     4621 ggtcagcaac acacggattt ttttagaaat cttatagctt tctgggtatt ttcgtttgac
     4681 catttctacg atttccgtgt ctaaaacagc atattgttgc gcatgggttc gttgtagaag
     4741 cagtcgtaaa tgattcacca gtcttgaata attcagtgaa aatggttctg aatggatatc
     4801 tgtttccaat tctgattcca ctaaatggat gatgtcagat acaatcgtca cttcacggat
     4861 actgcgatgg ttattgttcc gaccgcttcg tccgctgtga atatggattg cgatatatcc
     4921 tgcttcgtca taagtatatg gaatcccaag ctcttttgtc agatactcta ctgcccattg
     4981 agcaatactg aattcatcac tgtaaagcac ttcgatttct cttaaaagtt tgttgcggat
     5041 gacgataccg ttattaatgt tctccgcaga aaaagcaatg tggtcggtca aagcgatcaa
     5101 tacatgttca ttcaactttt ccatcaaaac agtttccgca tgatcaatga tcgtttctgc
     5161 tgcaaataaa aagcgttcat caatctgatt aagtaaattt tgcaacttga tttgaccttc
     5221 tggttccatg acaaatatcc gttcgacatc acgatcaaaa atcaaatcat ttctttttct
     5281 gtcaaatcca atcccttttc caatagctac tttttcctgt ccaccgtcat ctaccaatac
     5341 tgcattttga ttaaagatct ttttgatttt catgcgcgca ccctttttga agatttggtt
     5401 ttcacgtttg ctagaccagt tgattgcggc caaacaaaaa tagacacgaa aaacctccta
     5461 gggaaaccat gttcctcaga gatttttcat gcctagtatg atccagtcac atgaaacgaa
     5521 ttattgttaa cgtaatcaat tttatataga cagttatgtt ttgtcaattc tttttttata
     5581 attatagtaa tttactggaa ttatcagaaa taaaaggaag aaataaatta agaaacttat
     5641 gttatttaat cgttggatct tttgcttatc ttattcgttg ttaaaaagct gaaagcgaag
     5701 gaaaaaaact ctacttaact gtatttctcc gttaggacat ctaaaaattt acgagcagca
     5761 ggagaaagag gctggtcttt tttccaaatg agattcagtg aagcttgtaa tggcggatcg
     5821 agtgggatga atattttttc cgtcccataa gtattgatga tcccatctag agctaatgca
     5881 ccaaaagtcc cgttatcgac catcaaagaa gcattgtaca ataagttata tgttccgacg
     5941 atcgataact gatctatgct gaaacctagc cattcagcta gttgactgtc cactgacgtt
     6001 tgccgggaaa tgatcaaagg aacagttttc agttcctgcg gatggatgac ggtttgcttt
     6061 gctaaaggat gatttcgatg tatcaaaagt ccccaacgat cttgggctgg cagtcgaaat
     6121 gactggtatt tttgtttgtt tgtcggttcg attacgagtc caaaatcaag taatccgcta
     6181 tccagtttgt ctatgatatc atctgcattc ccgctatata aatgaaactg gatatcagga
     6241 tgcgccttga tcaacgaatg aaggctatca gaaatgaaag agattgcttt agtttcgcct
     6301 ccgccaatgt agatttctcc agagatgatt gcgtcatttg ttaaattgtt cgccgttttt
     6361 tctaccaacg acaagatttc ttttcctttt gaataaagat atcgaccaga atccgtcaac
     6421 tgtatctctc gggagccccg agtgaaaagt gtcacaccaa gttcttcttc taaatctttc
     6481 agttgttttg agagagtagg ttgcgtgata tgcagagatt ttgctgctcg gctgatattt
     6541 ttttctctag ctactgctaa aaaatacgtc agtatacgaa tatccatttt ttccctcctg
     6601 tttttaaaaa agcataccac taagtatagt taaaaggaat agttaagtat gttttataag
     6661 tattagacat gataagccgt ccgttataaa gtaaggataa aaggagggag caaaatgaca
     6721 agcctcatcg aaaaacaaat cgtcaataaa gagattcgag taacggatcc gctctttgaa
     6781 gtgatccatc agatccaagc tgaaaacgaa gagcctttag cagcgctgaa tactgggtac
     6841 catgaaccag cagatatccg caaacggcta gaaaatatca ttagtgacaa agtagatgat
     6901 acggtgactg ttctgctgcc tttttataca gatttcggca aacatattag tatagggaaa
     6961 aatgtcttta tcaatcgtca agtgatgttc gttgacttag gtggcatctg tttagaagat
     7021 tcagtattga ttggtcctcg tgtcaacctc atcacggtga accatctaac cgatccaaaa
     7081 gaacgaagag gcttgttagt aaagccaatc cacatcaaga aaaatgcttg gatcggagca
     7141 ggagcaacta ttctgccagg cgtaacgatt ggcgagaatg ccattgttgc agcgaatgca
     7201 actgttacga aagatgtccc agacaatacc atcgttgcag gaatccctgc caaaatcgtc
     7261 aaacctgtcg aacggattat ttgaacagta agatgaaata agagatagtg agtataagca
     7321 agagattttt caaaacagga ggagaataga atgaatgatt tatcagaaaa agtgattgtc
     7381 atcatgggcg cttcaagcgg aatcggtgaa gcaacaacga agctattagc agaaaaaggg
     7441 gctaaactag ttatagctgc acgccgagaa gatcgcctaa aagcaataaa agaatcttta
     7501 ccagaagctg agctatatat tcaaacagca gatgtaagag attttgcaca agtccaagca
     7561 gttatcgatt tagcgatgga aaagttcggt cgaatcgatg tattgtacaa taatgcagga
     7621 atcatgccaa ccgctccatt agttgaaggt caccgtgatg aatggcaaaa tatgcttgat
     7681 atcaacatca tgggtgtgtt aaatggaatt tccgccgtac ttccaatcat ggaaaaacaa
     7741 aaatctgggc atatcatttc aactgattct gtggcgggac atgttgttta tcctgattcc
     7801 gccgtttatt gcggaacaaa atttgctgtc cgtgcaatca tggaaggatt acgtcaagag
     7861 caacggcaaa ataacatcaa atctacgatc atctctccag gagctgttca aactgaatta
     7921 tatcaaacca tcagcgacaa aaaggctgct cttgaacttc atgaagcgca aaaagaatgg
     7981 ggattgacct ccgaagatat agcttctgct gtagcatttg cgatagaaac gccagaccgg
     8041 atgtctgtca gtaacatgat tatccgtccg acgacacagg aagtataatc cataacggat
     8101 aatatccaaa gagaattact tgttaaatag ttattcaaac gaccatcaat ttaaggcgtg
     8161 aatggagaag aatattcttc atttacgtct ttttatgtag aaaaagcaaa tttatcaaaa
     8221 agaaacaaat gttatttaaa tatggacatt gacttgcttt tactttttta gttacactgt
     8281 tatttaggaa aagtttcata attcaaagga gaaaaaagat gaaagcaaag aatttattat
     8341 ttagcgttat tcttttagga aatctagcag ttgccaacac aacagtgcta gctgaagaat
     8401 cgacagaaac tgtcgcaact cagacatcga gttcttcaga aacaggaatt gaaaacgata
     8461 cagagagtac tttgcagtca gctactgtct cagaaaatac aatttcaacc gaagaaccaa
     8521 caactgaaac aacagaacaa acacaaaccg aagacagtac atcagcagaa gctcagaaca
     8581 atccagagaa tgcagaagaa atcacgaacc aattgacaga tgggcaaaca ttgacacata
     8641 cccatcaagc agatttgtct gaattcgaaa actatactgg ctatgctttt tatgctcgct
     8701 catctgctaa ttctcaacaa gcgttcattg atagtattgc ctcaactgca caaagtttgg
     8761 caagtgccaa tgacttatat gcatcagtca tgattgctca agccatcgtt gaaagtggct
     8821 gggggaacag tactttggct tctgccccta attacaatct atttgggatt aaaggaagct
     8881 ataatggcca atctgttacg atgcctactt cggaatatgt gaatgggcaa tggattacgg
     8941 tgaatgccgc ttttagaaaa tatccttcgt acaaagaatc attgcaagat aacgtaacgg
     9001 tattgaagac gacttctttt cagccaggcg tttactacta ttccggtgca tggaaaagca
     9061 atacgaactc ttacaaagat gctacggctt ggctaacagg tcgttatgcc actgcgccta
     9121 attatggttc tacattgaac aatgtaatcg aaacctataa tctgacacag tatgatacag
     9181 caccaacttc aacttctccg atgtatcgtc tgtataaccg tcatacagga gaacatttat
     9241 atacattgaa tgccggagaa aaaaattatc tgccaactgt aggctgggaa tatgaaggga
     9301 ttgcttggca agcaccaaac agcggacaac ctgtctaccg tttatacaat ccttacagtg
     9361 gagaccatca ttacacaatg gcacaatctg agatcaactc tttaacaaaa atcggttggc
     9421 gttatgaagg tctaagtttt tattctggtg gttccaagcc aatttatcga ctatttaatc
     9481 caaatgaaaa aactggtacc catcactata ccttgagtgc taaggaaaga gattggctaa
     9541 caccgatggg ctggagatat gaaggaatag gattttatgg ttattaaaaa gaggtagtga
     9601 aaaagctgcc ctgcatcaag tagtaagaac agccaaacaa aaacagattt tcatgttttt
     9661 tgtttggttg aacttattac cgcagatgca agtttttgaa caccgtttac tcaaaaaagg
     9721 ttgtgacaac atcttgtcat aactttttta ttactgttta agcatactga tccaatttct
     9781 aatattcgac gggattcttg caaaaggcga tttcggaaat ttttggcggt gtaaaatttt
     9841 ctactgcaga agagctatct tctatagttt gataagaatc aataatcttg gttttagcgt
     9901 tgtgctttct ttatcatttt ttccgttcat tctacaaaaa atttcttttc tctatacttt
     9961 tctattgaga gcgttttttt tattacacag ctgattcttt gacttttttc tttttttatt
    10021 ctattattga caagtcaatc gttgacgagt caattattag aaaggaggaa attatgtctt
    10081 tagaagagat tagtcacctt ttatatcaaa tcaaattagc cgatcaaaaa atcgtccaga
    10141 tctttgaaga aaatatcggt ataagtctta ctagatacga gatcatgatg agactgaaag
    10201 aagaaaatcc attgctacaa agcagtttgc aagaaaagtt gcagattgat caaggagcag
    10261 ttactcgtca tctgaaggta ttggaagcaa atggctatgt ttcgcgtcag agaaatcctc
    10321 agaacaaccg ggaagtgtat gtagcgctaa cagaaaaagc ccagaagaaa atcgagcatt
    10381 gtgaaatgga ccataaagat acaggttccg tgctatcccc ggctttcagc gatgtagaaa
    10441 tgaaacaatt tctaacactt ttagataaat tgaataccca actttgcaat ataacaacag
    10501 aaacgaaaga ggttaataat aatggaacaa aaaaatgatt tttcaacaat tatgactggt
    10561 agaagatccg ttcgcgtata tgatgaaaca tacaaaatcc cacacgaaga aatgctggaa
    10621 atgatcaaag aagcgacgac tgcaccttct tctgtcaata tgcaaccatg gcgctttgtg
    10681 gtcgctgaaa gcgaggaagc aaaagaaatc ttgcgtcctt tgatccgttt caatacgaga
    10741 caaaatgata cttcttctgc aatggtcatg atttttggcg atatgcaatg ttacgaatat
    10801 ggcgaagaaa tctataacca agcttacgaa tcagggaaga tgccaaaaga agtcagagat
    10861 caacaattag ctgcgatcat tccttattac aagagttttt caagagaaga aatgaacgat
    10921 gtagtcaaag tcgattctag cttagcggct atgcaattca tgttagttgc gcgtgatcat
    10981 ggctatgaaa caaatccaat tggtggagtc gaagcagatc agttggcaga ggcatttggt
    11041 ttggataaag accgttatgt tccagttatt attttatcaa taggaaaagc ggtagaagaa
    11101 ggttacgagt ctgttcgttt agcaccagaa aagatcacta cgttcgaata aaaggttttc
    11161 agttactatt cagtagctat tgcttttttt gaatcgtgtg tggtaaccta ataaaaaagg
    11221 aggtcggaaa aatgactgca tcgatgaaat tacgtttcga acttttgaat aacaactaaa
    11281 taaattcaaa agacatgtat aaacaacaat ttcatggatg gagtatgtcc attttttcga
    11341 acgacagtag aataggtgaa agctatgaca gatttggtga tttagtcata gttatttcgt
    11401 tcagagtagg aaaagatgtg atgcagtttt tttgcaaaca gatttttctg ctctttttta
    11461 gtatcgataa ttgttgtttt acatgaaata ggagtgtaaa acatatggaa aatttagcag
    11521 taaatataac aaatctacaa gtcagctttg gcaaccagct agaactatct attgattctc
    11581 ttcgtgtcta tcagcaagat cgtataggga tcataggaga aaatggtgtc ggtaaatcga
    11641 ctttgctcaa actaatagcc ggtgaacttt ttcccgatca tgggaaaatc caaacagaga
    11701 tcaccttcaa ctacctgcct caattaacct atctcgctga agcaaaggac ctaaatttgg
    11761 aattagccag tcatttccag ttaagactgg aagaaacttc agagcggaaa tggagcggag
    11821 gggaagaacg aaagatcgag ttgatacgtc ttctttcttc ttatgaacaa gggatgcttc
    11881 tagacgagcc aacaacccat ctagatagaa aaagtattga tcgactgatt gaagagcttc
    11941 gttattatta tggtacgctg gtttttgtta gtcatgatcg ctattttcta gatgagctag
    12001 catcgaaaat ctgggaagta aaagacggag aaatccgaga gttttcgggg aattatagtg
    12061 cctatctcac tcaaaaggaa ttggagaaaa agactcagct acgagaagca gagtcgatca
    12121 tgaaagagaa aaaacgattg gaaaaatcga tccaagaaaa gaaaaaacaa gcggaaaagt
    12181 tggaaaaagt gtccagtaaa aagaaaaagc aacaaatcag accggatcgg ttgtcttcct
    12241 ctaaacaaaa agacagtgta caaaaagcca tccaaaagaa tgcgaaaaca ttagagagaa
    12301 gactccaaaa aataggagaa acaaccaagc cgcagcagat gaaacaaatc cgttttccag
    12361 taccaaaatc tcttgaactc cacagccgct atcccatcat gggacaaaat gtccaattgg
    12421 aaagaagtgg gagaacatta ctggtaaatg gtgattttca gttttcttta ggtaaaaaaa
    12481 tcgcgattgt cggtgaaaat ggttcaggta agacaacctt attagaacat atccgcaaac
    12541 aaggagaagg aatccttctc tctccgaaag taagctttca agtatatcag caaaagggtt
    12601 atcaaatgac atctgaagaa tccatcattc gttttgtcat gagacaaaca gagttttcag
    12661 aatcgcttgt ccgtagtttg ctgaatcact tagggtttgc tcaggaaact ttgacgaaac
    12721 cgttatgtac attaagtggg ggagaagcga cccgtctgac gattgctttg ctttttacta
    12781 agccaagtaa tgtgttgctg ttagatgaac cgactaattt tattgatatg gcaacgatcg
    12841 aagctttaga gaagctaatg caaatatatc cgggaacgat tttgtttact tctcatgatt
    12901 cttactttgt cgagcgtacg gctgatgaag tttatgaaat aaaagggcag aaaataaaaa
    12961 aagtacttac gagaaatttt taaatgtgct acgatgattt tcgtgacaaa tttaaaggag
    13021 tggtacagat tgcctacaaa taaaaaagaa ggaataattt ttacaacaat gatgtgtttt
    13081 ttgatggtct tggggatgag cgcgtataat ttatggctgc atcaagatct tcatttatca
    13141 agtttgttga ttggtctagt gcctggattc gtggtggctt tcattttgga tgtcttcatc
    13201 atcggtgtgc tggcgaaaaa aattgccttt aaactaccag taaatccaga aagcaaggtc
    13261 caaatgatct taactatttc atgcttgatg gttttaggaa tggtgacatg tatgtcttta
    13321 ttcggtgtga tcatggaaca aggaatacct gatcaattat tctctgctta tatgaatgct
    13381 tggaaaatga atgtgattgc cgctttaccg ttgcagttga tcatcgttgg cccgctttca
    13441 agaagtgtgc taaaagcaat tcaaagtaat gaatgatgga acactgttat ttgaaaaaag
    13501 gccttggcat gctttttgtc atagtctctt gaatgcagtt ctagaaaaat agtgatccga
    13561 acgataggtt ttggcctgtc gttcggatcg ctttttcttt tccaactgta ttgctctttt
    13621 attgaagata atttgctctt caatagatat ttctagaaag gttctgttta tcccttactc
    13681 aaaaaactgc tgcatttgtt ctcttacttg ctgacaccat tggagttcct gctgacaaag
    13741 cataattctg cgctggatca caacataacg tccaaattct tgtttcttgt ctagcgagag
    13801 gtcattcaat tttttttgat ttttttgcat gattttgttc agctgttgtt ctctagtgaa
    13861 tagcagtcca gtagctgttg ttttatcgag cgtcgaaaaa gcatagattt ttgctagaaa
    13921 ttcatctttt tgcgtaggag cgggagtttc ctctttgatc cattcctcta caagagcacg
    13981 tccttcatca gtcaagtggt agatcttttt ttgagagtgc tcgtctttgt ccaaaacggt
    14041 cacataaccc tgctggtcta acttggcaag cgttgtatag atctgactgt gatgggcttc
    14101 ccaaaaaatt gtgatcagct gcttcaattc atacccagaa cgtggtttgg ataaaagcac
    14161 gcataataat atataggcta aagtattcat aaaaatccta cctctcgtct tattttcttt
    14221 attatatcac agtaaagttt ccacgtttta catgtgcata tttacatgta aaataaatca
    14281 tgtatgatgc taatagagag aaagggatgg aaatattgga gaatcaaata gatatacaag
    14341 aacaaacaaa tgaagaaaca aaggggaaaa gttcagcgct agttgtagca gctacctgta
    14401 tgatcgcttt tatgggagtg ggtctagtag acccaatctt aaaaacgatt gctgcacagt
    14461 taaacgctac gccagctgaa acgaccctgt tatttactag ttacatgtta gtcactggtg
    14521 tggtgatgct atttacaggt ttcttatcta gtcggatcgg tttgaaaaaa acattgatga
    14581 caggattgtt tatcatcgtt gtattcgctg gtcttggcgg attatctggg aatatcggaa
    14641 tgctgattgg gttacgtgcc ggctggggtg tcgggaatgc tttatttgtc tctactgctt
    14701 tagcaacgat cgtcagtatt ttagttggta acacagaaaa agcaatcatg atgtatgaag
    14761 cagcacttgg ctgcggaatg gctgttggcc ctctagtcgg tggggtcttg ggcagtggtt
    14821 catggcgtta tccatttttt ggggtagcat ttttgatgtt ttgcggtttt atagccctag
    14881 cggtactttt acctgaaact gagaaaccaa agagaaaagt aggcctttgg gaaggtgtca
    14941 aagcgttaag caatcataaa cttcgttcag ttggactaat cgcattgtta tataatttcg
    15001 gattctttac tttacttgcg tatgcgccat ttttattgat tggctattct gaattagaag
    15061 tcggttttgt attttttggc tggggtgtgc ttctggctat tgcttcgatt ttcgttgcac
    15121 cggctcttga gcggaagttt acgacttatc ggacaatttt agcagcattt gtcttattca
    15181 ttatttgttt gctgttatta ggagctggaa cttctatgcc agtccttgta ccgatcagca
    15241 ttgtgttagc aggatttttc caaggaatta tcaatacact gttgacgacg attgctatgg
    15301 aaataccagg tctgcaacga aacgttgctt cgtccagcta tagttttgtc cgctttttcg
    15361 gtggagcttt agcaccattt attgcaggtg tgattggtga acatattggt gaaagctatg
    15421 cgttttattt tgcaggtgcc attgttctta tcagtgtatg ttgtatcatt tatcaccgta
    15481 attattttgc tacaaatgaa gaagaataag aaatcagagg ttgtgaaaaa gctgtcctgc
    15541 atcaagtcat aagaa
//
LOCUS       DACCVZ010000250        14453 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.guided.068, whole genome shotgun sequence.
ACCESSION   DACCVZ010000250 DACCVZ010000000
VERSION     DACCVZ010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.guided.068"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            complement(75..1367)
                     /locus_tag="IVW63_003054"
     CDS             complement(75..1367)
                     /locus_tag="IVW63_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP7861241.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSECRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
     gene            1434..1745
                     /locus_tag="IVW63_003055"
     CDS             1434..1745
                     /locus_tag="IVW63_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7861242.1"
                     /translation="MFWKIKKMLVSSTNIKKYRAKKIKERQAQGIEIAKKKGKFKGRQ
                     HKFKENDPRLKHAFDLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRD
                     S"
     gene            1745..3889
                     /gene="topB"
                     /locus_tag="IVW63_003056"
     CDS             1745..3889
                     /gene="topB"
                     /locus_tag="IVW63_003056"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP7861243.1"
                     /translation="MSTVILAEKPSQALAYASALKQSTKKDGYFEIKDPLFTDETFIT
                     FGFGHLVELAEPGHYDEKWQNWKLESLPIFPDRYDFEVAKDKGKQFKIVAELLKKANT
                     IIVATDSDREGENIAWSIIHKANAFSKDKTFKRLWINSLEKDVIRSGFQNLQPGMNYY
                     PFYQEAQTRQIADWLIGMNASPLYTLNLQQKGVQGTFSLGRVQTPTLYLIFQRQEAIE
                     NFKKEPFFEVEASIKVNQGSFKGVLSPTQRFKTQEELLAFVSSKQAKIGNQEGIIADV
                     QTKEKKTNSPSLFSLSSLQSKVNQLYKATASQTLKAMQGLYEAKLLSYPRTDTPFITE
                     NEFAYLKANFGKYSGFLGLDLEMVQTEPRKRYVDGSKVQEHHAIIPTKQVPTESALAK
                     MDDLQRKIYALVVKTTVAMFLPDYLYEETKIQTKVADLLFQSIGKTPKQEGWKILFKQ
                     QTKEEKEDVQTLPLVIIGERAEVGVKSVEKETQPPKAFTEGTLLTAMKTANKTVDDEE
                     AIKILQEVEGIGTEATRASIIEALKQKEYIQVIKNKLVVTEKGKLLCQAVESQHLLTS
                     AEMTAKWETYLKKIGKREGNQENFITNIKKFIVHLLEAVPNDIEKLNFSDYQEQKEKE
                     AEKSIVGKCPKCGNNIVLKKSFYGCSNYPECKFTLAEHFRKKKLTKTNVKELLEGKET
                     LVKGIKNKEKKPYNAVVKIGEKGYIDFISFSK"
     gene            4009..4248
                     /locus_tag="IVW63_003057"
     CDS             4009..4248
                     /locus_tag="IVW63_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013646120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAP7861244.1"
                     /translation="MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMEIRLRSKLKSVLIVHYLKILYNRN"
     gene            4297..4381
                     /locus_tag="IVW63_003058"
                     /pseudo
     CDS             4297..4381
                     /locus_tag="IVW63_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
     gene            4506..5243
                     /gene="erm(B)"
                     /locus_tag="IVW63_003059"
     CDS             4506..5243
                     /gene="erm(B)"
                     /locus_tag="IVW63_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAP7861245.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(5440..8406)
                     /locus_tag="IVW63_003060"
     CDS             complement(5440..8406)
                     /locus_tag="IVW63_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HAP7861246.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            8552..9127
                     /locus_tag="IVW63_003061"
     CDS             8552..9127
                     /locus_tag="IVW63_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016204422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP7861247.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            9341..10036
                     /gene="vanR"
                     /locus_tag="IVW63_003062"
     CDS             9341..10036
                     /gene="vanR"
                     /locus_tag="IVW63_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAP7861248.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            10014..11168
                     /locus_tag="IVW63_003063"
     CDS             10014..11168
                     /locus_tag="IVW63_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAP7861249.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            11383..12351
                     /locus_tag="IVW63_003064"
     CDS             11383..12351
                     /locus_tag="IVW63_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAP7861250.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            12344..13375
                     /gene="vanA"
                     /locus_tag="IVW63_003065"
     CDS             12344..13375
                     /gene="vanA"
                     /locus_tag="IVW63_003065"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAP7861251.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAFITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            13381..13989
                     /locus_tag="IVW63_003066"
     CDS             13381..13989
                     /locus_tag="IVW63_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAP7861252.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         4720 a         2582 c         2928 g         4223 t
ORIGIN      
        1 ttgtcaaatg atgttggtaa agagaaatct tagaataatt ggagatcaag tggatcagtt
       61 cctcttgatc ttttttagtt gaaaatcaat gcgttgccat gacgaatcat gatgcgcaat
      121 ttgaaattat aaaagctacg aaagccatat gcatttcgtt ttaacacttt gatatggttg
      181 ttcagacatt caagtgggcc atttgaataa ctttgttgta aagcattttt gatttgtggc
      241 agaaatttct ggaacgttct caaggtcgtc tgatagcctt cgggaagcat gatattattg
      301 gtaagtagtt cttcaaacga tacgtagtct cgttccttta cagcgtaaag aaagtcttga
      361 tataactgat agcctacacg caaagcaggg ctccctttca gtaagcgatc cacaatatcg
      421 gtctctgtta aatgagcttt gaagccaggt cgccaaaggc gtcgagtata atcaagcttg
      481 cgttcatctt tttgaagaag tttccagtat ctttttaatt gcttacctaa ttgatagtgt
      541 ttttgttctt tgctttttaa tagttggttc gtttctttga ttcgatgatt gcgaaaggta
      601 cgaccaatat gttggacgat gtgaaaccgg tcaataatca gctgtgcttt tggaaacagc
      661 tttttaacga gcgatacata aggagcgtac atatcaatca cgatccattc gaccgcttca
      721 cgaatttctc gtgaaaaatg actaaaataa cgttttaaaa aaggcagttg tcggttctcg
      781 acaatgtcca acaagcgctg tgtttgtcca tccatcatga tgaaactcat agcacctgaa
      841 acaccccgaa ctgatttgaa ttcatcaaaa caaagtacct taggtaacgg tgtccgaaaa
      901 ggattcaacg gacgataaaa tcgcttcata atacggtaaa cagaagagac cgatagattt
      961 ttctgagcgg cgatctctgt cattgaggta ttttttttca gacgagtcac gacagaccag
     1021 cggactttct cactgatgaa acagtgtttt ttcgcaacag aagtatctgc gacaaaggtc
     1081 cgctgacaag ctttgcattt gaagcgttgc tttttcaatt cgaggtaggt acggcattca
     1141 gaaacatcgt tcattaacaa ccggacggtt gttgtacccc aacgcacaat atctgaagca
     1201 atctggtgtt tacagtggat gcattcttgg gctgtataaa tcaagtttcc acgataaata
     1261 tgacagattt gccctttgta tttttctttt gtgagacaat tttcgttaaa agtaactgat
     1321 aagtctagaa tatctaatgt ttctttgata aggtgagtgt aagacatctt gattcctcct
     1381 tttgggttgg ttcgccaaat taattctaaa ggatttcaag gtgtcttttc tatatgtttt
     1441 ggaaaataaa aaagatgctg gtgtcatcca ccaacatcaa aaagtataga gctaaaaaaa
     1501 ttaaggaacg tcaggcacaa ggaatcgaaa ttgctaagaa aaaaggcaaa ttcaaaggtc
     1561 gtcagcataa atttaaagaa aatgatccac gtttaaagca tgctttcgat ttgtttttga
     1621 atggtttatc cgataaagaa gttgaagaac aaactggaat caatcgccga acgtttagaa
     1681 ggtatcgagc aagatataac gtgacagtcg atcaaagaaa aaacaatgaa aagagggata
     1741 gttaatgagt acggttattt tagctgaaaa accaagccag gcattagcct acgcaagtgc
     1801 tttaaaacaa agcaccaaaa aagacggtta ttttgagatc aaagacccac tatttacaga
     1861 tgaaacgttt atcacctttg gttttgggca tttagtggaa ttagcagaac caggtcatta
     1921 tgacgaaaag tggcaaaatt ggaaacttga atctttgccg atttttcctg atcgatacga
     1981 ttttgaagtt gcaaaagata agggaaagca gtttaaaatt gttgcagaac ttctcaaaaa
     2041 ggcaaataca attattgttg caacagatag cgacagagaa ggtgaaaata tcgcctggtc
     2101 gattatccat aaagcaaatg ccttttcaaa agataaaaca tttaaaagac tatggatcaa
     2161 tagcttagaa aaagatgtaa tccgaagcgg ttttcaaaat ttgcaacctg gaatgaatta
     2221 ctatcccttt tatcaagaag cgcaaacacg ccaaattgcc gattggttga tcggcatgaa
     2281 cgcaagccct ttgtatacgt taaatttaca acagaagggc gtacaaggta cattttcact
     2341 aggacgtgtt caaacgccca ccttatacct tatttttcag cgccaggaag ccatagagaa
     2401 ttttaaaaaa gaaccttttt tcgaggtgga agctagtata aaagtaaacc aagggtcgtt
     2461 taagggcgtt ctaagcccca cacagcgttt taaaacccaa gaggagcttt tagcttttgt
     2521 ttcttctaaa caagctaaaa taggcaatca agaggggata attgctgatg ttcaaaccaa
     2581 agagaagaaa acgaatagtc cgagtttgtt ttctttaagt agtttgcaat caaaagtcaa
     2641 tcagctttat aaagcgacag cgagccaaac tttaaaagct atgcaaggac tgtatgaagc
     2701 aaaattattg agttatccaa gaacagatac accatttatt acagagaacg aatttgctta
     2761 tttaaaagcg aattttggca aatatagcgg ttttttagga cttgatcttg aaatggttca
     2821 aacagagcct agaaagcgtt atgtggacgg tagtaaggta caggaacacc acgccattat
     2881 cccaacaaaa caagtaccta ccgaatctgc attagcgaaa atggacgatt tacaacgaaa
     2941 aatttatgct ttagtcgtta aaacgaccgt tgccatgttt ttacctgatt acttgtatga
     3001 agaaaccaag atacaaacga aagtagctga tttgctgttt caatcgatcg gaaagacacc
     3061 aaagcaagaa gggtggaaaa ttcttttcaa acaacaaacc aaagaagaaa aagaggacgt
     3121 tcaaacgtta ccactcgtta tcattggcga acgtgccgaa gttggtgtta agagtgttga
     3181 aaaagaaacg caaccgccaa aagcttttac agagggtaca ttattaactg ctatgaaaac
     3241 ggcgaataaa acggttgatg atgaagaagc aatcaagatt ttacaagaag ttgaggggat
     3301 tggaacagaa gcgacaagag caagtattat tgaagcgtta aaacaaaaag aatatatcca
     3361 agtgattaag aataagcttg ttgtaactga aaaaggaaaa ttattgtgcc aggcagttga
     3421 aagtcagcac cttttaacga gtgctgaaat gacggctaaa tgggaaacgt atttaaaaaa
     3481 aatcggtaaa agagaaggca atcaagagaa ctttattacg aatatcaaaa aattcattgt
     3541 tcatttactg gaagctgtac ctaacgatat agaaaaacta aatttttctg attaccagga
     3601 acagaaagaa aaagaagcag aaaaaagtat tgtaggaaaa tgtcctaagt gtggcaacaa
     3661 tattgtatta aaaaaatcgt tttatggttg ttcaaattat cctgaatgta agtttacttt
     3721 agctgaacat tttagaaaga aaaaactaac caaaacgaat gtaaaagaat tactggaggg
     3781 aaaagaaacc ctggtaaaag gaatcaaaaa caaagagaaa aagccctaca atgccgttgt
     3841 aaaaattggg gaaaagggat atattgattt tatatctttc tcaaaataaa cataaaagcc
     3901 ctttaaagag ggcttttata tattaatcac aaatcactta tcacaaatca caagtgattt
     3961 gtgattgttg atgataaaat aagaataaga agaaatagaa agaagtgagt gattgtggga
     4021 aatttaggcg cacaaaaaga aaaacgaaat gatacaccaa tcagtgcaaa aaaagatata
     4081 atgggagata agacggttcg tgttcgtgct gacttgcacc atatcataaa aatcgaaaca
     4141 gcaaagaatg gcggaaacgt aaaagaagtt atggaaataa gacttagaag caaacttaag
     4201 agtgtgttga tagtgcatta tcttaaaatt ttgtataata ggaattgaag ttaaattaga
     4261 tgctaaaaat ttgtaattaa gaaggaggga ttcgtcatgt tggtattcca aatgcgtaat
     4321 gtagataaaa catctactgt tttgaaacag actaaaaaac agtgattaca cagataaata
     4381 aatacgttag attaattcct accagtgact aatcttatga ctttttaaac agataactaa
     4441 aattacaaac aaatcgttta acttctgtat ttatttatag atgtaatcac ttcaggagtg
     4501 attacatgaa caaaaatata aaatattctc aaaacttttt aacgagtgaa aaagtactca
     4561 accaaataat aaaacaattg aatttaaaag aaaccgatac cgtttacgaa attggaacag
     4621 gtaaagggca tttaacgacg aaactggcta aaataagtaa acaggtaacg tctattgaat
     4681 tagacagtca tctattcaac ttatcgtcag aaaaattaaa actgaacatt cgtgtcactt
     4741 taattcacca agatattcta cagtttcaat tccctaacaa acagaggtat aaaattgttg
     4801 ggaatattcc ttaccattta agcacacaaa ttattaaaaa agtggttttt gaaagccatg
     4861 cgtctgacat ctatctgatt gttgaagaag gattctacaa gcgtaccttg gatattcacc
     4921 gaacactagg gttgctcttg cacactcaag tctcgattca gcaattgctt aagctgccag
     4981 cggaatgctt tcatcctaaa ccaaaagtaa acagtgtctt aataaaactt acccgccata
     5041 ccacagatgt tccagataaa tattggaagc tatatacgta ctttgtttca aaatgggtca
     5101 atcgagaata tcgtcaactg tttactaaaa atcagtttca tcaagcaatg aaacacgcca
     5161 aagtaaacaa tttaagtacc gttacttatg agcaagtatt gtctattttt aatagttatc
     5221 tattatttaa cgggaggaaa taattctatg agtcgctttt gtaaattata aaagaattgt
     5281 tttaatgcag gtataaaaga tgaacccgca ccaacaccgc caccaatttt agatagcttt
     5341 gattggtaca tttttagcgc tattcggggt agcgtcagga aaatgcggat ttacaacgct
     5401 aagcctattt tcctgacgaa tccctcgttt ttaacaacgt taagaaagtt ttagtggtct
     5461 taaagaattt aatgagacta ctttctctga gttaaaatgg tattctccta gtaaattaat
     5521 atgttcccaa cctaagggcg acatatggtg taacaaatct tcattaaagc tacctgtccg
     5581 ttttttatat tcaactgctg ttgttaggtg gagagtattc caaatactta tagcattgat
     5641 aattatgttt aaagcactgg ctctttgcaa ttgatgctgt atggtgcgtt ctctaagctc
     5701 accttgtttt ccgaagaaaa tagctcttgc caatccattc atggcttctc ctttattcaa
     5761 tcctctttgt atttttcttc ttaatgattc atccgatata taattcaaaa taaagatcgt
     5821 tttttctatt cggcccatct cacgtaaggc tgtagctaag ctgttttgtc ttgaatagga
     5881 acctagcttc cccataataa gggatgctga aactgttccc tcccttatag aatgagctaa
     5941 tcgcaaaaca tcctcataat tttctttaat gacctttgta tttatttgtc cacgtaaaat
     6001 ggcttctagt tttggatact cacttgcttt atctatcgta aataattttg agtccgataa
     6061 atcccttatt cttggggcaa atttaaatcc taataaatga gtcagtccga atatttggtc
     6121 agtgtaaccg gcagtgtctg tataatgttc ctctatgttt agatccgtct catgatgtaa
     6181 caaaccatcc aaaacatgaa tcgcatctct tgaattagta tgaataatct ttgtgtagta
     6241 agaagagaat tgatcacttg taaatcggta gatggtggct ccttttccag ttccataatg
     6301 tggatttgca tctgcatgta gtgatgaaac acctagctgc attctcatac catctgacga
     6361 agatgttgta ccgtcgcccc aatagaaagg caattgtaat ttatgatgaa agtttactaa
     6421 tatggcttgg gctttattca tggcatcttc atacatgcgc cattgagata cattggctag
     6481 ttgcttatat gtaagtccgg gtgtggcttc ggccatcttg ctcaagccaa tattcattcc
     6541 cattcctaaa agggcagcca tgataatgat tgtttcttcc ttatctggtt ttcgattatt
     6601 ggaagcatga gtgaattgct catgaaatcc tgttatatgg gccacatcca tgagtaaatc
     6661 agttaatttt attcttggta gcatctgata aaggcttgca ctaaattttt ttgcttcttc
     6721 tggaacatct ttttctaagc gtgcaagtga tagctttcct ttttcaagag aaaccccatc
     6781 taacttattg gaattggcag ctaaccactt taacctttca ttaaagctgc tggttctctc
     6841 cgttatataa tcttcgaatg ataaactaac tgataatctc gtattcccct tcgattgatt
     6901 ccatgtatct tccgaaaaca aatattcctc aaaatcccta tattgtctgc tgccaacaat
     6961 ggaaacatct cctgcccgaa catgctcccg aagttctgtt aaaacagcca tttcatagta
     7021 atgacgatta attgttgtac catcatcctc gtataaatgt cttttccatc gttttgaaat
     7081 aaaatccaca ggtgagtcat caggcacttt tcgctttcca gattcgttca ttcctcggat
     7141 aatctcaaca gcttgtaaaa gtggctcatt tgcctttgta gaatgaaatt ccaatactct
     7201 taatagcgtt ggcgtatatt ttcttagtga ataaaaccgt ttttgcagta agtctaaata
     7261 atcatagtcg gcaggacgtg caagttcctg agcctcttct actgaagaga caaaggtatt
     7321 ccattcaata accgattcta aaaccttaaa aacgtctaat ttttcctctc ttgctttaat
     7381 taatgcttgt ccgatgttcg taaagtgtat aactttctca tttagctttt taccgttttg
     7441 tttctggatt tcctcttgag ccttacgacc ttttgataac aaactaagta tttgcctatc
     7501 atgaatttca aacgctttat ccgttagctc ctgagtaagt tgtaataaat agatggttaa
     7561 tatcgaataa cgtttatttt cttgaaagtc acggaatgca tacggctcgt atcttgagcc
     7621 taagcgagac agctgcaaca ggcggttacg gtgcaaatga ctaatttgca ctgtttctaa
     7681 atccattcct cgtatgtatt cgagtcgttc tattattttt agaaaagttt cgggtgaagg
     7741 atgacccggt ggctctttta accaacccaa tatcgtttta ttggattcgg atggatgctg
     7801 cgaggtaata atcccttcaa gcttttcttt ttgctcattt gttagagatt tactaaccgt
     7861 attaaatagc ttcttttcag ccattgccct tgcttcccac accattcttt caagtgtagt
     7921 gatagcaggc agtataattt tgttttttct tagaaaatct atgcattcat gcagtagatg
     7981 aatggcatca ccattttcca aagctaattg atgaaggtac ttaaatgtca ttcgatattc
     8041 actcagggta aaagttacaa agtcgtattc acttcgaatt tctttcaaat gatcccaaag
     8101 tgtattttcc ctttgaggat aatgatcaag cgaggatgga ctaacaccaa tctgtttcga
     8161 tatatattgt atgaccgaat ctgggatgct tttgatatga gtgtatggcc aaccgggata
     8221 ccgaagaaca gctaattgaa cagcaaatcc taaacggttt tcttccctcc ttcgcttatt
     8281 aactatttct aaatcccgtt tggaaaaagt gaagtaggtc cccagtatcc attcatcttc
     8341 agggatttgc ataaaagcct gtctctgttc cggtgtaagc aattctctac ctctcgcaat
     8401 tttcattcag tatcattcca tttctgtatt ttcaatttat tagttcaatt atatatcaat
     8461 agagtgtact ctattgatac aaatgtagta gactgataaa atcatagtta agagcgtctc
     8521 ataagacttg tctcaaaaat gaggtgatat tttgcggaaa atcggttata ttcgtgtcag
     8581 ttcgactaac cagaatcctt caagacaatt tcagcagttg aacgagatcg gaatggatat
     8641 tatatatgaa gagaaagttt caggagcaac aaaggatcgc gagcaacttc aaaaagtgtt
     8701 agacgattta caggaagatg acatcattta tgttacagac ttaactcgaa tcactcgtag
     8761 tacacaagat ctatttgaat taatcgataa catacgagat aaaaaggcaa gtttaaaatc
     8821 actaaaagat acatggcttg atttatcaga agataatcca tacagccaat tcttaattac
     8881 tgtaatggct ggtgttaacc aattagagcg agatcttatt cggatgagac aacgtgaagg
     8941 gattgaattg gctaagaaag aaggaaagtt taaaggtcga ttaaagaagt atcataaaaa
     9001 tcacgcagga atgaattatg cggtaaagct atataaagaa ggaaatatga ctgtaaatca
     9061 aatttgtgaa attactaatg tatctagggc ttcattatac aggaaattat cagaagtgaa
     9121 taattagcca ttctgtattc cgctaatggg caatattttt aaagaagaaa aggaaactat
     9181 aaaatattaa cagcctccta gcgatgccga aaagcccttt gataaaaaaa gaatcatcat
     9241 cttaagaaat tcttagtcat ttattatgta aatgcttata aattcggccc tataatctga
     9301 taaattatta agggcaaact tatgtgaaag ggtgataact atgagcgata aaatacttat
     9361 tgtggatgat gaacatgaaa ttgccgattt ggttgaatta tacttaaaaa acgagaatta
     9421 tacggttttc aaatactata ccgccaaaga agcattggaa tgtatagaca agtctgagat
     9481 tgaccttgcc atattggaca tcatgcttcc cggcacaagc ggccttacta tctgtcaaaa
     9541 aataagggac aagcacacct atccgattat catgctgacc gggaaagata cagaggtaga
     9601 taaaattaca gggttaacaa tcggcgcgga tgattatata acgaagccct ttcgcccact
     9661 ggagttaatt gctcgggtaa aggcccagtt gcgccgatac aaaaaattca gtggagtaaa
     9721 ggagcagaac gaaaatgtta tcgtccactc cggccttgtc attaatgtta acacccatga
     9781 gtgttatctg aacgagaagc agttatccct tactcccacc gagttttcaa tactgcgaat
     9841 cctctgtgaa aacaagggga atgtggttag ctccgagctg ctatttcatg agatatgggg
     9901 cgacgaatat ttcagcaaga gcaacaacac catcaccgtg catatccggc atttgcgcga
     9961 aaaaatgaac gacaccattg ataatccgaa atatataaaa acggtatggg gggttggtta
    10021 taaaattgaa aaataaaaaa aacgactatt ccaaactaga acgaaaactt tacatgtata
    10081 tcgttgcaat tgttgtggta gcaattgtat tcgtgttgta tattcgttca atgatccgag
    10141 ggaaacttgg ggattggatc ttaagtattt tggaaaacaa atatgactta aatcacctgg
    10201 acgcgatgaa attatatcaa tattccatac ggaacaatat agatatcttt atttatgtgg
    10261 cgattgtcat tagtattctt attctatgtc gcgtcatgct ttcaaaattc gcaaaatact
    10321 ttgacgagat aaataccggc attgatgtac ttattcagaa cgaagataaa caaattgagc
    10381 tttctgcgga aatggatgtt atggaacaaa agctcaacac attaaaacgg actctggaaa
    10441 agcgagagca ggatgcaaag ctggccgaac aaagaaaaaa tgacgttgtt atgtacttgg
    10501 cgcacgatat taaaacgccc cttacatcca ttatcggtta tttgagcctg cttgacgagg
    10561 ctccagacat gccggtagat caaaaggcaa agtatgtgca tatcacgttg gacaaagcgt
    10621 atcgactcga acagctaatc gacgagtttt ttgagattac acggtataac ctacaaacga
    10681 taacgctaac aaaaacgcac atagacctat actatatgct ggtgcagatg accgatgaat
    10741 tttatcctca gctttccgca catggaaaac aggcggttat tcacgccccc gaggatctga
    10801 ccgtgtccgg cgaccctgat aaactcgcga gagtctttaa caacattttg aaaaacgccg
    10861 ctgcatacag tgaggataac agcatcattg acattaccgc gggcctctcc ggggatgtgg
    10921 tgtcaatcga attcaagaac actggaagca tcccaaaaga taagctagct gccatatttg
    10981 aaaagttcta taggctggac aatgctcgtt cttccgatac gggtggcgcg ggacttggat
    11041 tggcgattgc aaaagaaatt attgttcagc atggagggca gatttacgcg gaaagcaatg
    11101 ataactatac gacgtttagg gtagagcttc cagcgatgcc agacttggtt gataaaagga
    11161 ggtcctaaga gatgtatata attttttagg aaaatctcaa ggttatcttt actttttctt
    11221 aggaaattaa caatttaata ttaagaaacg gctcgttctt acacggtaga cttaataccg
    11281 taagaacgag ccgttttcgt tcttcagaga aagatttgac aagattacca ttggcatccc
    11341 cgttttattt ggtgcctttc acagaaaggg ttggtcttaa ttatgaataa catcggcatt
    11401 actgtttatg gatgtgagca ggatgaggca gatgcattcc atgctctttc gcctcgcttt
    11461 ggcgttatgg caacgataat taacgccaac gtgtcggaat ccaacgccaa atccgcgcct
    11521 ttcaatcaat gtatcagtgt gggacataaa tcagagattt ccgcctctat tcttcttgcg
    11581 ctgaagagag ccggtgtgaa atatatttct acccgaagca tcggctgcaa tcatatagat
    11641 acaactgctg ctaagagaat gggcatcact gtcgacaatg tggcgtactc gccggatagc
    11701 gttgccgatt atactatgat gctaattctt atggcagtac gcaacgtaaa atcgattgtg
    11761 cgctctgtgg aaaaacatga tttcaggttg gacagcgacc gtggcaaggt actcagcgac
    11821 atgacagttg gtgtggtggg aacgggccag ataggcaaag cggttattga gcggctgcga
    11881 ggatttggat gtaaagtgtt ggcttatagt cgcagccgaa gtatagaggt aaactatgta
    11941 ccgtttgatg agttgctgca aaatagcgat atcgttacgc ttcatgtgcc gctcaatacg
    12001 gatacgcact atattatcag ccacgaacaa atacagagaa tgaagcaagg agcatttctt
    12061 atcaatactg ggcgcggtcc acttgtagat acctatgagt tggttaaagc attagaaaac
    12121 gggaaactgg gcggtgccgc attggatgta ttggaaggag aggaagagtt tttctactct
    12181 gattgcaccc aaaaaccaat tgataatcaa tttttactta aacttcaaag aatgcctaac
    12241 gtgataatca caccgcatac ggcctattat accgagcaag cgttgcgtga taccgttgaa
    12301 aaaaccatta aaaactgttt ggattttgaa aggagacagg agcatgaata gaataaaagt
    12361 tgcaatactg tttgggggtt gctcagagga gcatgacgta tcggtaaaat ctgcaataga
    12421 gatagccgct aacattaata aagaaaaata cgagccgtta tacattggaa ttacgaaatc
    12481 tggtgtatgg aaaatgtgcg aaaaaccttg cgcggaatgg gaaaacgaca attgctattc
    12541 agctgtactc tcgccggata aaaaaatgca cggattactt gttaaaaaga accatgaata
    12601 tgaaatcaac catgttgatg tagcattttc agctttgcat ggcaagtcag gtgaagatgg
    12661 atccatacaa ggtctgtttg aattgtccgg tatccctttt gtaggctgcg atattcaaag
    12721 ctcagcaatt tgtatggaca aatcgttgac atacatcgtt gcgaaaaatg ctgggatagc
    12781 tactcccgcc ttttgggtta ttaataaaga tgataggccg gtggcagcta cgtttaccta
    12841 tcctgttttt gttaagccgg cgcgttcagg ctcatccttc ggtgtgaaaa aagtcaatag
    12901 cgcggacgaa ttggactacg caattgaatc ggcaagacaa tatgacagca aaatcttaat
    12961 tgagcaggct gtttcgggct gtgaggtcgg ttgtgcggta ttgggaaaca gtgccgcgtt
    13021 agttgttggc gaggtggacc aaatcaggct gcagtacgga atctttcgta ttcatcagga
    13081 agtcgagccg gaaaaaggct ctgaaaacgc atttataacc gttcccgcag acctttcagc
    13141 agaggagcga ggacggatac aggaaacggc aaaaaaaata tataaagcgc tcggctgtag
    13201 aggtctagcc cgtgtggata tgtttttaca agataacggc cgcattgtac tgaacgaagt
    13261 caatactctg cccggtttca cgtcatacag tcgttatccc cgtatgatgg ccgctgcagg
    13321 tattgcactt cccgaactga ttgaccgctt gatcgtatta gcgttaaagg ggtgataagc
    13381 atggaaatag gatttacttt tttagatgaa atagtacacg gtgttcgttg ggacgctaaa
    13441 tatgccactt gggataattt caccggaaaa ccggttgacg gttatgaagt aaatcgcatt
    13501 gtagggacat acgagttggc tgaatcgctt ttgaaggcaa aagaactggc tgctacccaa
    13561 gggtacggat tgcttctatg ggacggttac cgtcctaagc gtgctgtaaa ctgttttatg
    13621 caatgggctg cacagccgga aaataacctg acaaaggaaa gttattatcc caatattgac
    13681 cgaactgaga tgatttcaaa aggatacgtg gcttcaaaat caagccatag ccgcggcagt
    13741 gccattgatc ttacgcttta tcgattagac acgggtgagc ttgtaccaat ggggagccga
    13801 tttgatttta tggatgaacg ctctcatcat gcggcaaatg gaatatcatg caatgaagcg
    13861 caaaatcgca gacgtttgcg ctccatcatg gaaaacagtg ggtttgaagc atatagcctc
    13921 gaatggtggc actatgtatt aagagacgaa ccatacccca atagctattt tgatttcccc
    13981 gttaaataaa cttttaaccg ttgcacggac aaactatata agctaactct ttcggcagga
    14041 aacccgacgt atgtaactgg ttcttaggga atttatatat agtagatagt attgaagatg
    14101 taaggcagag cgatattgcg gtcattatct gcgtgcgctg cggcaagata gcctgataat
    14161 aagactgatc gcatagaggg gtggtatttc acaccgccca ttgtcaacag gcagttcagc
    14221 ctcgttaaat tcagcatggg tatcacttat gaaaattcat ctacattggt gataatagta
    14281 aatccagtag ggcgaaataa ttgactgtaa tttacggggc aaaacggcac aatctcaaac
    14341 gagattgtgc cgtttaaggg gaagattcta gaaatatttc atacttccaa ctatatagtt
    14401 aaggaggaga ctgaaagaga gtataaaata ttttgtgtaa atgaaaaaat cca
//
LOCUS       DACCVZ010000251         5589 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.guided.136, whole genome shotgun sequence.
ACCESSION   DACCVZ010000251 DACCVZ010000000
VERSION     DACCVZ010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5589
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.guided.136"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            <1..401
                     /locus_tag="IVW63_003067"
     CDS             <1..401
                     /locus_tag="IVW63_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAP7861253.1"
                     /translation="EDIQEIRETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEG
                     IKMNSGNLISSWMIQQDSLFTKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINL
                     LESYTMNKPSDNFSFRFAFRAKSKKTSPIK"
     gene            561..2447
                     /locus_tag="IVW63_003068"
     CDS             561..2447
                     /locus_tag="IVW63_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP7861254.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            2459..3406
                     /locus_tag="IVW63_003069"
     CDS             2459..3406
                     /locus_tag="IVW63_003069"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAP7861255.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            3426..3953
                     /locus_tag="IVW63_003070"
     CDS             3426..3953
                     /locus_tag="IVW63_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP7861256.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(4016..4669)
                     /locus_tag="IVW63_003071"
     CDS             complement(4016..4669)
                     /locus_tag="IVW63_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAP7861257.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            4801..>5589
                     /locus_tag="IVW63_003072"
     CDS             4801..>5589
                     /locus_tag="IVW63_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP7861258.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPV"
BASE COUNT         2025 a          959 c         1165 g         1440 t
ORIGIN      
        1 atgaagatat ccaagaaatc agagagacat atcaaaaaaa tactcagttg attattgaaa
       61 gtttagataa cttgactgat atttatgatg aaacgatggt tcaatttttt atccagcaac
      121 gcaaacttga aggaataaaa atgaactcgg ggaatttgat ttcttcgtgg atgatccagc
      181 aagatagtct gtttacgaaa aaaatgctaa gaggttatta tcttgaaaga aaaatcattg
      241 atgaatacga agttgctgaa aaaatcacga cgttttctgc gaacagctat cgcaggaata
      301 tcaatttgtt agaatcttat acgatgaaca aaccatctga taacttttct ttccgatttg
      361 cgtttcgagc aaagtcaaaa aaaacgagtc caataaaata aaaaggtaaa aattttcaag
      421 ttttataaaa aacaaaacat atcagaacag gatcgaatcg gtcctgttct ttttttgaga
      481 acacaaaaag aacaaatacc aaaaaaattt tcctgaagtt cactattttt atgatacaat
      541 atccaagata aggagggaac atgttgaaag aattaaaagt aactgacctc aaaaaaactt
      601 atggtgaaaa agatttgttt gaccagattt cttttttggt ccacgaaaaa gaccgtatcg
      661 ggttgattgg gacgaacggg acgggtaaaa caagtctctt aaatattatt gccggtatcg
      721 atagcagcga cggtgatcgg caaacagtgt tttatccaac tgattaccgt attggttatc
      781 tttctcaagc agctgaattt tccgatgaat taactgttct ccaagcagtc tttcaaggaa
      841 acagcccctt gatccaaact gttcgagcat atgaggaagc attgatcgaa ctaggggaaa
      901 acggagaaga ccctgatgtg caaaaacgtt atgctaaagc agaagaacaa atgaataaag
      961 aagatgcttg gactacagat accaacgcaa agattatttt gcaaaaatta ggaatcagtg
     1021 aattagataa aaaaatcagt actttatcag gtggtcagaa aaaacgagtt agtctggcgc
     1081 aagtgttgat tgatgaaccc gatttactat tactagacga accaacaaac catttagatt
     1141 atgaagcgat cgagtggttg gaaaactatt tgaaacaata ccgtggcgca ctattgatgg
     1201 ttacccacga tcgttatttt ctagatagag tagcaaaccg aatcttcgaa ctttcatttg
     1261 gaaaattata cgagtataaa ggaaattatg aagcttacgt cttagaaaaa gcagaacgtg
     1321 atcgtgtaga agtagaacaa gaagaaaagc gcaagcggct ttataaacag gaattagctt
     1381 ggatgagggc tggcgtacag gcacgtggca ccaagcagca agcacggatc aaccgtttcg
     1441 aagatctaaa ggagaacttg taccaagtaa accaagaaga tgatttagag ctgaacctag
     1501 cgacacaacg tttagggaaa aaagtactgg aaatcaaaga tggcagttac cgtataaatg
     1561 accaaacact gctagaacat ttagatttat tgattcaatc tcgggaaaga ctaggtatta
     1621 ctggtaaaaa tggtgcggga aaatcgacat tgcttaatat tctagctggc agaattcccc
     1681 tggatagcgg tacaatgtct atcggtgaaa cggttcatct tgcgtattat acacaagaaa
     1741 atgaagaaat ggcaccagat aaacggatga ttgcttactt acaagaagct gctgaagaag
     1801 caaaaacagc agatggcagt caaatcggag tagcagaatt acttgaacga tttttatttc
     1861 caagatttat gcatgggaca ctgataggca aactttcagg cggagaaaaa cgccggttat
     1921 ttttgttgaa actgctgatt cagcaaccta atgttttatt attggatgaa ccgaccaatg
     1981 atttggacat agcaacattg acgattttgg aagattattt tagaagtttt ccaggtgctg
     2041 tgatcactgt ttcccatgac cgttatttct tggacaaggt agcagataag ttattagtat
     2101 tccaaggaaa cggaaaacaa gaactttatt acggaaacat gtccagttat ttactgaagc
     2161 aaaaagagac ccagcagcct gctgaaaaag cgaaaccaaa aatacagagc aaggaacctg
     2221 ctgaaaagaa gaaattatct tacatggaac aaaaagaatg ggaaacgatt gaagatgaga
     2281 ttgcagaact tgaagaaaaa atctcattgc tccaagaaga gatgaatcat caaggagata
     2341 atttcactcg attacaagaa ttgcaaaacg acgtatctga aacagaagca caacttgaag
     2401 aaaaaatggc acggtgggaa tacttgagtg aatgggtaga agattaggag gaaaaaggat
     2461 ggaacaagcg tatcttgact taggaagaaa attgttggaa gaagggcatc gtaaagaaga
     2521 cagaacaggc acaggcacat taagcttatt cggataccaa atgcggtttg atctgcaaaa
     2581 agggtttcct ttgttaacaa cgaaacgagt accttttgga ttgatcaaaa gcgaattgct
     2641 ttggttttta aaaggagata cgaatatccg ctatctatta caaaataaaa accatatttg
     2701 ggatgaatgg gcatttgaac gctacatcaa aagtccagac tataatggac cagatatgac
     2761 tgattttggc catagatgtt tgacagatcc tgaattcaat gaagaatata aaaagcagag
     2821 caagcttttt tgcgagaaga tcctaaccga tgattccttt gctgaaacat acggcgatct
     2881 tggacacatc tacggctatc aatggcgtca ctgggaaaca aaagacggtg gctttatcga
     2941 tcaaatcaaa caagtgatcg aagcaatcaa aaagactcct gattctagaa gattgatcgt
     3001 ttctgcatgg aatccggaag atgttcctag catggctttg cctccttgtc atacgatgtt
     3061 tcaattttat gttcaagagg gacggctaag ctgccaattg tatcaacgca gtggggatgt
     3121 gtttctaggc gttccgttca acattgcaag ttatgcgttg ctgactcacc taattgcaca
     3181 tgaaacaggt ttagcggttg gcgaatttgt tcacacatta ggagatgctc atctttatat
     3241 caatcatatc gaacaaatga aagaacaatt gagccgagaa atacgcgcat ttccgacttt
     3301 agttttgaat caggaaaagc agtcagtatt tgattttgag atggaagata tccaattaga
     3361 aggatatgac ccacatccgg cgatcaaagc tcctatcgct gtttagaatc agaaaggatg
     3421 agaaaatgtt agctgcaatt tgggcacagg atgaaaacgg attgattgga aaagaagacc
     3481 gtcttccttg gcgtttgcca aatgatctga aattcttcaa acaaatgaca gaagcaaata
     3541 cactagtgat gggacgaaaa acattcgaag ggatgggtag ccgtccgttg ccgaatcgtc
     3601 agacgattgt tttgacgaga gattcttcct ataaagcaga aggcgtgcat gtcatgcata
     3661 gtgtggaaga cgtgcttgct ctggaaaaag aaacagacgg tatctttttc atcgctggag
     3721 ggtcagctgt ttatcaagaa tttctgccat tttgtacgat attataccgt acagtcatcc
     3781 atcatgtatt cgatggagat gcttattttc cacctgttga ctggtctgat tggtcactga
     3841 tcaatactag tcaaggagaa atggatgaaa aaaatcgtta tccgcatcaa tttgaaacgt
     3901 atcagcgtaa tgagaatcct gtaaaaagcg ggacaggcga attgacgata taaaaaagct
     3961 atggatagac tagctgttat ttagagctgt cccatccata gctttatttt ttttattaag
     4021 taaagaataa aacagagaag tacataaaac ctgcacctaa cataacaaac aaatgccaaa
     4081 caacatgcat atagcggata gaattcaagc tataaaagaa tgcgcctatc gtgtaagaaa
     4141 gcccgcctgc taccatcaaa ataacaccag tcattccaag agagtgataa agaggaacag
     4201 cagccacgac acagagccac cccataaaaa tatagatgat cgtagatact tttgatactc
     4261 tctcccgttt atgcaacgtc aacgctttat atataatgcc aagaatcgca aacaaccaga
     4321 ttaatacaaa taaagtccaa cctagccatc ctcggatact cagcaaacaa aaaggagtat
     4381 aacttcctgc aatcaaaaga aaaatcgaac tatgatcgaa tacttggaac accttttttg
     4441 cttttgtaaa aatcaatgaa tgaaacaaag tagacgttaa aaataaaaga atcatcatcg
     4501 atccatagat agcataagag acaatatgga gggaggaatg caagtgggca ccttttacta
     4561 aaagaaccac tagtcccgcg atactcaatc cagtcccaat tccatgggtg actgcattaa
     4621 acacttcatt taatatttca tacgttcgat taaatttcgt tttttccatg aaaacggctc
     4681 ctttactagg tgtaattaat gaaaaatcat tatttgtctg ttatactaaa aatagaaatt
     4741 gtcttacatg tagtttaaca tgaataaggc atcttgttaa agaaagagag agagaaaata
     4801 atgacaaatg taaaaatcgt aacagattct tcatgtacga tggaaaaaaa tgtacgcgat
     4861 gctttaggca ttcgtgtcat gccgctatcc atcatgatcg acggaacagt atatcccgat
     4921 gatgaccaac tagacggcga aagatttatg gaaatgatgg cgaaagcaaa aaatctgccc
     4981 aaaacaagcc aaccaccaat tggagaattc atctcgatgt atgatgagct aggagaagac
     5041 ggcagtgaag tgatttcgat ccatatgaca aaaggcttga gtggaacagt agaagcagca
     5101 agacaagcca gtaatctaac aaaaacgaaa gtaacggtta tcgacagtga taccactgac
     5161 caaggattat cttttcaggt aattcgagca gctgaattag caaaagaagg taaaacagta
     5221 gagaaaatcc ttgaagaagt caaaaaagta caagacaata caaaattata catcggaata
     5281 tccacactag ataacttggt aaaaggtgga agaatcagcc gaacaactgg tttgctgtct
     5341 agtgttttga acatacgcgt ggtgatgaat ttcgcccatt ctgaattaat ccctgtaact
     5401 aaggggcgag gaaagaaaac gttcgataaa tggtttaata atttgaaaaa tgaactgaaa
     5461 gaattgccaa atgtgcgaca aatcggtatt tcacatgcgg atgcaaaaga attggcgcaa
     5521 gaattcaaag agggtttgca agaattattc ccggacatgc atatccctgt actgcatacg
     5581 aatccggtt
//
LOCUS       DACCVZ010000252         1738 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.guided.192, whole genome shotgun sequence.
ACCESSION   DACCVZ010000252 DACCVZ010000000
VERSION     DACCVZ010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.guided.192"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            48..959
                     /locus_tag="IVW63_003073"
     CDS             48..959
                     /locus_tag="IVW63_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HAP7861259.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1112..1597
                     /gene="vanZ"
                     /locus_tag="IVW63_003074"
     CDS             1112..1597
                     /gene="vanZ"
                     /locus_tag="IVW63_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAP7861260.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
BASE COUNT          613 a          237 c          331 g          557 t
ORIGIN      
        1 aggaggacaa tttatttaca caaaattatt gacgctcccg actgaaaatg aagaagttgt
       61 tttttttatt gttattgtta ttcttaatat acttaggtta tgactacgtt aatgaagcac
      121 tgttttctca ggaaaaagtc gaatttcaaa attatgatca aaatcccaaa gaacatttag
      181 aaaatagtgg gacttctgaa aatacccaag agaaaacaat tacagaagaa caggtttatc
      241 aaggaaatct gctattaatc aatagtaaat atcctgttcg ccaagaaagt gtgaagtcag
      301 atatcgtgaa tttatctaaa catgacgaat taataaatgg atacgggttg cttgatagta
      361 atatttatat gtcaaaagaa atagcacaaa aattttcaga gatggtcaat gatgctgtaa
      421 agggtggcgt tagtcatttt attattaata gtggctatcg agactttgat gagcaaagtg
      481 tgctttacca agaaatgggg gctgagtatg ccttaccagc aggttatagt gagcataatt
      541 caggtttatc actagatgta ggatcaagct tgacgaaaat ggaacgagcc cctgaaggaa
      601 agtggataga agaaaatgct tggaaatacg ggttcatttt acgttatcca gaggacaaaa
      661 cagagttaac aggaattcaa tatgaaccat ggcatattcg ctatgttggt ttaccacata
      721 gtgcgattat gaaagaaaag aatttcgttc tcgaggaata tatggattac ctaaaagaag
      781 aaaaaaccat ttctgttagt gtaaatgggg aaaaatatga gatcttttat tatcctgtta
      841 ctaaaaatac caccattcat gtgccgacta atcttcgtta tgagatatca ggaaacaata
      901 tagacggtgt aattgtgaca gtgtttcccg gatcaacaca tactaattca aggaggtaag
      961 gatggcggaa tgaaaccaac gaaattaatg aacagcatta ttgtactagc acttttgggg
     1021 taacgttagc tttttaattt aaaacccacg ttaactagga cattgctata ctaatgatac
     1081 aacttaaaca aaagaattag aggaaattat attgggaaaa atattatcta gaggattgct
     1141 agctttatat ttagtgacac taatctggtt agtgttattc aaattacaat acaatatttt
     1201 atcagtattt aattatcatc aaagaagtct taacttgact ccatttactg ctactgggaa
     1261 tttcagagag atgatagata atgttataat ctttattcca tttggcttgc ttttgaatgt
     1321 caattttaaa gaaatcggat ttttacctaa gtttgctttt gtactggttt taagtcttac
     1381 ttttgaaata attcaattta tcttcgctat tggagcgaca gacataacag atgtaattac
     1441 aaatactgtt ggaggctttc ttggactgaa attatatggt ttaagcaata agcatatgaa
     1501 tcaaaaaaaa ttagacagag ttattatttt tgtaggtata cttttgctcg tattattgct
     1561 cgtttaccgt acccatttaa gaataaatta cgtgtaagat gtctaaatca agcaatctga
     1621 tctttcatac acataaagat attgaatgaa ttggattaga tggaaaacgg gatgtgggga
     1681 aactcgcccg taggtgtgaa gggttctgtt gcaaagtttt aaatctacta tcaaataa
//
LOCUS       DACCVZ010000253          952 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.guided.224, whole genome shotgun sequence.
ACCESSION   DACCVZ010000253 DACCVZ010000000
VERSION     DACCVZ010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.guided.224"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            339..887
                     /gene="aac(6')"
                     /locus_tag="IVW63_003075"
     CDS             339..887
                     /gene="aac(6')"
                     /locus_tag="IVW63_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAP7861261.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          338 a          138 c          190 g          286 t
ORIGIN      
        1 ttctaccgat tccctttgct tttttgtaat tatctaaaaa ttctaaaaat taagattatt
       61 atatgaaaac aggttttatt tgtcaattca taattggttt tttttaaagc aaaagataat
      121 ctatatcatg atgaacaaac agagtttttt cctccaattg atggctttcc tgatctttcc
      181 tattttgaat aaagtgtttc tgtataattt tttattttat aagtaagata aataatgaaa
      241 gaatagagat actgattggt agctaaagat ttttgagcga gaacatttcg ttttttcaaa
      301 aggactgtta gaataagcaa gaacaagggg gaagacgtat gataatcagt gaatttgacc
      361 gtaataatcc agtattgaaa gatcagcttt ctgatttact gagactgact tggccggaag
      421 aatatggaga cagctcggca gaagaagtag aagaaatgat gaatccagaa cgaatcgcgg
      481 tagcagcggt agaccaagat gagttagtag gatttattgg tgcaatccct caatacggta
      541 tcacaggttg ggaattgcat ccattagttg tagaaagctc ccgacgaaag aaccaaatag
      601 gtactcgatt agtcaattac ttagaaaaag aagtagcttc cagaggagga atcacgattt
      661 atttaggtac ggatgattta gaccatggaa caacgttaag tcaaacggac ctgtatgagc
      721 atacatttga taaagtggct tccatccaga accttcgtga acatccgtat gaattctatg
      781 aaaaattagg ttataaaatc gtaggtgtct taccaaatgc aaatggctgg gacaaaccgg
      841 atatttggat ggcaaaaacg attattcctc gaccaaattc tcaataataa aaagaggttg
      901 tgacagaagt aatcagcttc aagaaataag aaggaattta cgaaaattac tt
//
LOCUS       DACCVZ010000254          545 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW16408
            SAMN14604054-rid9903023.guided.237, whole genome shotgun sequence.
ACCESSION   DACCVZ010000254 DACCVZ010000000
VERSION     DACCVZ010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN14604054
            Sequence Read Archive: SRR11551421
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000744157.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000744157.1
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/23/2020 23:49:55
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,076
            CDSs (total)                      :: 3,012
            Genes (coding)                    :: 2,953
            CDSs (with protein)               :: 2,953
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 3 (16S, 23S)
            partial rRNAs                     :: 1, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 35 of 59
            Pseudo Genes (incomplete)         :: 22 of 59
            Pseudo Genes (internal stop)      :: 11 of 59
            Pseudo Genes (multiple problems)  :: 8 of 59
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..545
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN14604054-rid9903023.guided.237"
                     /isolate="UW16408"
                     /isolation_source="blood culture"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Berlin"
                     /collection_date="2017"
                     /collected_by="Robert Koch Institut"
     gene            41..538
                     /gene="dfrG"
                     /locus_tag="IVW63_003076"
     CDS             41..538
                     /gene="dfrG"
                     /locus_tag="IVW63_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAP7861262.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
BASE COUNT          204 a           58 c          118 g          165 t
ORIGIN      
        1 gaaattagat ggtaaattag ttaaaaaggc tgtgttataa atgaaagttt ctttgattgc
       61 tgcgatggat aagaatagag tgattggcaa agagaatgac attccttgga ggattcccaa
      121 ggactgggaa tatgttaaaa atactacaaa gggacatccg ataatattag gtaggaagaa
      181 ccttgaatca atcggaagag ccttacctga cagaagaaat attattctga cgagagataa
      241 ggggtttacc tttaatggtt gtgaaattgt tcattcaata gaagatgttt ttgagttatg
      301 taaaaacgaa gaagaaattt ttattttcgg aggagaacag atttataatt tgtttttccc
      361 ttatgttgag aaaatgtaca tcacaaaaat acatcatgaa ttcgaaggag atactttttt
      421 tccagaagtg aattatgagg aatggaatga ggtatttgcc caaaaaggga taaagaatga
      481 taaaaatccg tataactact attttcatgt atatgaaaga aaaaacttat tgagttaacg
      541 ggtgc
//
